# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3716 PF12511.3 EMD58042.1 - 3.2e-10 39.4 5.8 4.1e-10 39.1 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) pKID PF02173.12 EMD58042.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 pKID domain zf-CCHC PF00098.18 EMD58043.1 - 3.7e-08 32.8 7.7 8.5e-06 25.4 1.4 3.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMD58043.1 - 0.0076 15.8 8.7 0.49 10.0 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EMD58043.1 - 2.9 7.4 13.5 0.55 9.7 0.1 3.3 3 1 0 3 3 3 0 Zinc knuckle DDE_1 PF03184.14 EMD58048.1 - 6.5e-34 116.9 0.0 7.2e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD58048.1 - 1.1e-07 31.6 0.0 1.3e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2894 PF11445.3 EMD58049.1 - 6.5 6.9 11.2 16 5.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Rabaptin PF03528.10 EMD58051.1 - 0.025 14.4 1.9 0.036 13.9 1.3 1.2 1 0 0 1 1 1 0 Rabaptin DUF1357 PF07094.6 EMD58051.1 - 0.16 11.3 2.1 0.22 10.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Zn_clus PF00172.13 EMD58051.1 - 0.19 11.6 7.5 0.94 9.4 5.2 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF899 PF05988.7 EMD58051.1 - 0.74 9.2 3.2 1.2 8.4 2.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) RVT_1 PF00078.22 EMD58052.1 - 0.00062 19.1 0.0 0.00062 19.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GvpG PF05120.7 EMD58054.1 - 0.088 12.6 3.3 0.1 12.3 2.3 1.0 1 0 0 1 1 1 0 Gas vesicle protein G Tropomyosin PF00261.15 EMD58054.1 - 0.16 11.0 4.7 0.18 10.8 3.3 1.0 1 0 0 1 1 1 0 Tropomyosin FlxA PF14282.1 EMD58054.1 - 0.28 11.1 1.7 0.31 10.9 1.1 1.3 1 1 0 1 1 1 0 FlxA-like protein Sugarporin_N PF11471.3 EMD58054.1 - 0.64 9.7 7.6 0.35 10.5 2.9 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Vpu PF00558.14 EMD58056.1 - 0.74 9.4 4.3 1.5 8.4 3.0 1.4 1 0 0 1 1 1 0 Vpu protein Disaggr_assoc PF08480.5 EMD58058.1 - 0.039 13.4 0.1 0.04 13.3 0.0 1.0 1 0 0 1 1 1 0 Disaggregatase related RVP_2 PF08284.6 EMD58059.1 - 0.00068 19.5 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EMD58059.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease ImpE PF07024.8 EMD58060.1 - 0.035 14.0 0.0 0.036 14.0 0.0 1.0 1 0 0 1 1 1 0 ImpE protein Apolipo_F PF15148.1 EMD58061.1 - 0.0084 15.4 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein F MukE PF04288.8 EMD58061.1 - 0.07 11.9 0.4 0.1 11.3 0.2 1.3 1 1 0 1 1 1 0 MukE-like family zf-CCHC PF00098.18 EMD58062.1 - 2.1e-06 27.3 2.0 3e-06 26.8 1.4 1.2 1 0 0 1 1 1 1 Zinc knuckle OrfB_Zn_ribbon PF07282.6 EMD58062.1 - 0.082 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_2 PF13696.1 EMD58062.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EMD58062.1 - 0.14 11.8 0.8 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DSHCT PF08148.7 EMD58067.1 - 0.009 15.2 0.8 0.014 14.6 0.5 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain DUF4174 PF13778.1 EMD58067.1 - 0.46 10.5 3.4 0.22 11.6 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) Zn_clus PF00172.13 EMD58067.1 - 0.57 10.1 7.4 1.4 8.8 1.8 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP-S26 PF14943.1 EMD58067.1 - 2.8 7.4 15.4 0.18 11.3 5.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 G0-G1_switch_2 PF15103.1 EMD58067.1 - 5.8 7.2 5.6 1.5 9.0 1.3 2.0 1 1 1 2 2 2 0 G0/G1 switch protein 2 RVP PF00077.15 EMD58070.1 - 0.01 15.7 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.6 EMD58070.1 - 0.075 12.9 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_1 PF03184.14 EMD58071.1 - 1.3e-08 34.2 0.0 1.4e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMD58072.1 - 1.5e-11 43.9 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD58072.1 - 4.1e-06 26.2 0.2 7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD58072.1 - 0.0031 17.6 1.0 0.0042 17.2 0.4 1.5 1 1 1 2 2 2 1 Winged helix-turn helix Drf_GBD PF06371.8 EMD58072.1 - 0.025 13.9 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_28 PF13518.1 EMD58072.1 - 0.047 13.6 0.1 0.29 11.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD58072.1 - 0.066 12.8 0.3 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DDE_1 PF03184.14 EMD58073.1 - 1.7e-13 50.2 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD58074.1 - 4.5e-09 36.2 0.1 6.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2789 PF10982.3 EMD58074.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2789) DUF3658 PF12395.3 EMD58076.1 - 0.086 12.4 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function zf-CCHC PF00098.18 EMD58078.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Thioesterase PF00975.15 EMD58079.1 - 0.003 17.8 0.0 0.0034 17.6 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Thioesterase PF00975.15 EMD58080.1 - 0.078 13.1 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain RVT_1 PF00078.22 EMD58082.1 - 0.00081 18.7 0.1 0.00082 18.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EMD58083.1 - 1.6e-08 34.2 0.1 1.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IL22 PF14565.1 EMD58083.1 - 0.11 12.5 0.1 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Exo_endo_phos_2 PF14529.1 EMD58085.1 - 4.7e-17 61.7 0.4 5e-17 61.6 0.3 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3130 PF11328.3 EMD58085.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 GTP_cyclohydroI PF01227.17 EMD58087.1 - 0.089 12.0 0.0 0.099 11.9 0.0 1.0 1 0 0 1 1 1 0 GTP cyclohydrolase I HTH_psq PF05225.11 EMD58089.1 - 1.5e-05 24.4 0.2 2.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain zf-CCHC PF00098.18 EMD58091.1 - 0.016 15.1 2.8 0.024 14.5 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle SF-assemblin PF06705.6 EMD58091.1 - 0.035 13.2 1.4 0.041 13.0 1.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DOR PF14839.1 EMD58091.1 - 4 7.1 10.7 9.9 5.8 7.4 1.6 1 1 0 1 1 1 0 DOR family HTH_29 PF13551.1 EMD58095.1 - 3.1e-08 33.7 0.2 3.9e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EMD58095.1 - 1.2e-06 28.0 0.1 2.1e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EMD58095.1 - 4.6e-05 22.7 0.3 0.027 13.8 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_1 PF11427.3 EMD58095.1 - 7.3e-05 22.3 0.2 0.00017 21.1 0.0 1.7 2 0 0 2 2 2 1 Tc3 transposase Sigma70_r4_2 PF08281.7 EMD58095.1 - 7.3e-05 22.1 0.0 7.3e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.1 EMD58095.1 - 9.7e-05 21.8 1.0 0.00012 21.5 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EMD58095.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 EMD58095.1 - 0.00017 21.1 0.0 0.00047 19.7 0.0 1.8 1 1 1 2 2 2 1 HTH domain HTH_Mga PF08280.6 EMD58095.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain PAX PF00292.13 EMD58095.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 'Paired box' domain HTH_7 PF02796.10 EMD58095.1 - 0.019 14.8 0.6 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.17 EMD58095.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_32 PF13565.1 EMD58095.1 - 0.027 15.2 0.5 0.25 12.1 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 EMD58095.1 - 0.029 13.9 1.6 5.5 6.6 0.0 2.6 2 1 1 3 3 3 0 AsnC-type helix-turn-helix domain SgrR_N PF12793.2 EMD58095.1 - 0.036 14.0 0.3 0.073 13.0 0.1 1.5 1 1 1 2 2 2 0 Sugar transport-related sRNA regulator N-term FeoC PF09012.5 EMD58095.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sigma70_r4 PF04545.11 EMD58095.1 - 0.042 13.1 0.2 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Crp_2 PF13545.1 EMD58095.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.4 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.2 EMD58095.1 - 0.046 13.3 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 MarR family Helicase_C PF00271.26 EMD58098.1 - 1.7e-07 30.9 0.0 4.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AvrE PF11725.3 EMD58098.1 - 0.56 7.1 8.7 0.73 6.7 6.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor DUF775 PF05603.7 EMD58098.1 - 9.7 5.6 6.3 31 4.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DEAD PF00270.24 EMD58099.1 - 2.2e-06 27.2 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMD58099.1 - 0.00018 21.3 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EMD58099.1 - 0.058 12.6 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein ImpE PF07024.8 EMD58100.1 - 0.034 14.0 0.0 0.036 14.0 0.0 1.0 1 0 0 1 1 1 0 ImpE protein RVP_2 PF08284.6 EMD58101.1 - 0.0044 16.9 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EMD58101.1 - 0.094 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease WCCH PF03716.9 EMD58102.1 - 1.1e-05 24.6 0.1 1.1e-05 24.6 0.0 3.2 4 0 0 4 4 4 2 WCCH motif zf-C4pol PF14260.1 EMD58102.1 - 1.1 9.3 6.7 1.6 8.7 1.7 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Steroid_dh PF02544.11 EMD58103.1 - 0.05 13.3 0.6 0.057 13.1 0.4 1.1 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Fun_ATP-synt_8 PF05933.8 EMD58103.1 - 0.059 13.4 0.3 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Condensation PF00668.15 EMD58104.1 - 4.8e-61 206.2 0.4 3.6e-36 124.5 0.0 3.2 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EMD58104.1 - 3.9e-06 27.0 0.2 4.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site RVT_1 PF00078.22 EMD58106.1 - 0.0042 16.4 0.1 0.0042 16.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SERTA PF06031.8 EMD58107.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 SERTA motif DUF1612 PF07756.7 EMD58107.1 - 0.062 13.4 0.1 0.075 13.1 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1612) Exo_endo_phos_2 PF14529.1 EMD58108.1 - 2.2e-15 56.3 0.3 2.4e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3130 PF11328.3 EMD58108.1 - 0.14 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 Condensation PF00668.15 EMD58109.1 - 5.1e-50 170.0 0.3 8.5e-50 169.2 0.2 1.4 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.23 EMD58109.1 - 1e-44 152.6 0.0 8.8e-31 106.7 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EMD58109.1 - 2.1e-16 59.9 0.0 2.3e-15 56.6 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD58109.1 - 2.3e-06 28.4 0.1 6.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Exo_endo_phos_2 PF14529.1 EMD58110.1 - 4.9e-12 45.5 0.0 1.7e-11 43.7 0.0 1.9 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMD58110.1 - 0.0055 16.6 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ComGG PF14173.1 EMD58111.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ComG operon protein 7 EnY2 PF10163.4 EMD58117.1 - 0.044 13.7 0.7 0.55 10.1 0.1 2.0 1 1 1 2 2 2 0 Transcription factor e(y)2 DDRGK PF09756.4 EMD58119.1 - 1.4 8.3 13.5 2.5 7.4 9.4 1.4 1 0 0 1 1 1 0 DDRGK domain DivIVA PF05103.8 EMD58119.1 - 2.8 8.0 16.1 4.4 7.3 8.5 2.2 2 0 0 2 2 2 0 DivIVA protein DSHCT PF08148.7 EMD58121.1 - 0.0092 15.2 0.8 0.014 14.6 0.5 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain DUF4174 PF13778.1 EMD58121.1 - 0.19 11.8 2.3 0.22 11.6 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) Phlebovirus_G2 PF07245.6 EMD58121.1 - 0.21 9.8 2.1 0.23 9.6 1.4 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Zn_clus PF00172.13 EMD58121.1 - 0.31 10.9 6.9 1.4 8.8 1.3 2.0 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP-S26 PF14943.1 EMD58121.1 - 3.1 7.3 15.5 0.18 11.3 5.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 G0-G1_switch_2 PF15103.1 EMD58121.1 - 3.2 8.0 4.9 1.1 9.5 1.1 1.9 1 1 0 2 2 2 0 G0/G1 switch protein 2 HET PF06985.6 EMD58122.1 - 1.7e-21 76.8 12.5 3.3e-19 69.4 8.2 3.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 EMD58122.1 - 5.9e-19 67.3 0.2 5.6e-09 35.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EMD58122.1 - 1.1e-14 54.0 0.0 1.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EMD58122.1 - 8e-12 44.9 0.1 2.7e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_22 PF13401.1 EMD58122.1 - 1.6e-08 34.7 0.3 8.2e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD58122.1 - 2e-08 34.4 2.5 2.5e-08 34.1 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EMD58122.1 - 4e-06 26.7 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase TPR_7 PF13176.1 EMD58122.1 - 9.4e-06 25.0 0.6 0.004 16.8 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD58122.1 - 2.6e-05 23.8 0.1 0.6 10.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.7 EMD58122.1 - 9.4e-05 22.1 0.0 0.00035 20.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EMD58122.1 - 0.00017 21.8 0.0 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_11 PF13414.1 EMD58122.1 - 0.00035 20.1 0.0 0.001 18.6 0.0 1.8 1 0 0 1 1 1 1 TPR repeat IstB_IS21 PF01695.12 EMD58122.1 - 0.0015 18.0 0.0 0.0045 16.4 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein PPR PF01535.15 EMD58122.1 - 0.0018 18.1 0.2 3.4 7.8 0.1 2.8 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 EMD58122.1 - 0.0045 17.1 1.8 0.45 10.9 0.1 3.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain AAA_25 PF13481.1 EMD58122.1 - 0.0049 16.2 0.0 0.015 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TPR_19 PF14559.1 EMD58122.1 - 0.0057 16.9 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD58122.1 - 0.006 17.2 0.0 0.03 15.0 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMD58122.1 - 0.013 15.8 0.3 6.7 7.4 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58122.1 - 0.016 14.7 0.5 2.1 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_33 PF13671.1 EMD58122.1 - 0.027 14.3 1.9 6.4 6.6 0.0 3.9 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.17 EMD58122.1 - 0.068 12.6 0.1 0.65 9.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EMD58122.1 - 0.069 13.9 0.0 0.23 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain PPR_1 PF12854.2 EMD58122.1 - 0.23 10.9 0.9 7.6 6.0 0.3 2.4 2 0 0 2 2 2 0 PPR repeat HemY_N PF07219.8 EMD58123.1 - 0.56 9.7 4.2 0.7 9.4 2.9 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Condensation PF00668.15 EMD58124.1 - 1.1e-34 119.6 0.0 2.2e-34 118.6 0.0 1.5 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EMD58124.1 - 8.4e-17 61.2 0.0 2.7e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site zf-CCHC PF00098.18 EMD58125.1 - 0.012 15.5 2.8 0.017 15.0 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EMD58125.1 - 0.058 13.3 2.4 0.079 12.8 1.7 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RNase_H PF00075.19 EMD58126.1 - 2e-05 24.9 0.1 3.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 RNase H DUF3716 PF12511.3 EMD58127.1 - 8.7e-09 34.8 5.5 8.7e-09 34.8 3.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) DUF4183 PF13799.1 EMD58129.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) DUF3417 PF11897.3 EMD58131.1 - 1.9 8.4 5.5 4.2 7.3 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3417) ExoD PF06055.7 EMD58132.1 - 0.056 12.5 0.3 0.058 12.5 0.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Exo_endo_phos_2 PF14529.1 EMD58133.1 - 1.9e-14 53.2 0.4 2e-14 53.1 0.3 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Robl_LC7 PF03259.12 EMD58134.1 - 0.38 10.3 2.0 1.7 8.2 0.2 2.4 1 1 1 2 2 2 0 Roadblock/LC7 domain DUF2894 PF11445.3 EMD58134.1 - 2.1 8.5 14.2 9.3 6.4 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) MHYT PF03707.11 EMD58137.1 - 0.087 12.9 1.3 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF2360 PF10152.4 EMD58138.1 - 0.94 9.7 6.3 1.9 8.7 0.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SDH_alpha PF03313.10 EMD58138.1 - 5.6 5.9 12.6 1.3 8.0 6.5 1.6 2 0 0 2 2 2 0 Serine dehydratase alpha chain Asp_protease_2 PF13650.1 EMD58140.1 - 2e-06 28.1 0.0 3.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EMD58140.1 - 0.00011 22.0 0.2 0.0015 18.3 0.1 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EMD58140.1 - 0.0041 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EMD58140.1 - 0.005 16.3 0.1 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EMD58141.1 - 0.016 15.1 2.8 0.024 14.5 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DOR PF14839.1 EMD58141.1 - 1.6 8.4 5.0 2.4 7.8 3.5 1.3 1 1 0 1 1 1 0 DOR family zf-CCHC PF00098.18 EMD58146.1 - 0.0097 15.7 1.4 0.015 15.2 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle HrpJ PF07201.6 EMD58146.1 - 0.03 14.3 0.6 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 HrpJ-like domain Ank_2 PF12796.2 EMD58147.1 - 5.2e-31 106.8 1.2 1.1e-18 67.3 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD58147.1 - 8.6e-27 91.5 4.5 2.1e-05 24.0 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EMD58147.1 - 1.7e-26 92.0 0.7 6.2e-11 42.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD58147.1 - 2e-24 83.2 0.5 0.00045 20.1 0.0 5.1 4 1 1 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMD58147.1 - 1.9e-21 75.6 3.4 7.1e-12 45.1 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) MDMPI_C PF07398.6 EMD58147.1 - 0.063 13.8 1.7 75 3.9 0.0 3.3 3 0 0 3 3 3 0 MDMPI C-terminal domain DUF4427 PF14468.1 EMD58147.1 - 0.065 12.9 2.4 31 4.3 0.0 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF4427) Ank_2 PF12796.2 EMD58148.1 - 9.7e-21 73.9 0.2 1.2e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD58148.1 - 1.5e-19 68.7 0.4 3.2e-09 36.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD58148.1 - 5e-16 57.2 0.2 4.9e-07 29.3 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMD58148.1 - 1.2e-12 47.9 0.4 1.7e-11 44.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD58148.1 - 3.2e-10 39.8 0.3 1.4e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HET PF06985.6 EMD58149.1 - 1.8e-22 79.9 10.5 3.3e-19 69.4 0.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Chromo PF00385.19 EMD58152.1 - 3.4e-08 33.0 1.8 4.8e-08 32.5 1.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LBR_tudor PF09465.5 EMD58152.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Herpes_DNAp_acc PF04929.7 EMD58154.1 - 0.054 12.4 0.0 0.054 12.4 0.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2231 PF09990.4 EMD58155.1 - 0.17 12.2 0.2 0.17 12.2 0.1 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) RVP_2 PF08284.6 EMD58157.1 - 0.00022 21.1 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EMD58157.1 - 0.022 14.3 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EMD58158.1 - 2.3e-06 27.2 12.4 2.7e-05 23.8 1.6 3.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMD58158.1 - 0.00036 20.1 3.4 0.16 11.6 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle Gon7 PF08738.5 EMD58159.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Gon7 family TPR_10 PF13374.1 EMD58161.1 - 1.4e-15 56.5 3.1 4.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD58161.1 - 5.3e-11 42.3 0.1 5.7e-11 42.1 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD58161.1 - 0.013 15.2 0.5 3.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58161.1 - 0.026 14.1 0.1 0.042 13.4 0.1 1.4 1 1 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 EMD58161.1 - 0.051 13.5 0.6 12 6.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3784 PF12650.2 EMD58162.1 - 9.4 6.2 8.5 1.9 8.4 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3658 PF12395.3 EMD58165.1 - 0.086 12.4 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function RNase_H PF00075.19 EMD58169.1 - 7.2e-11 42.5 0.1 8.4e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 RNase H DUF3203 PF11462.3 EMD58169.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) DDE_1 PF03184.14 EMD58170.1 - 4.2e-05 22.8 0.0 4.6e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_6 PF14259.1 EMD58171.1 - 0.0021 17.9 0.0 0.06 13.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD58171.1 - 0.081 12.5 0.1 0.25 10.9 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EpsG PF14897.1 EMD58172.1 - 0.036 13.0 0.5 0.048 12.5 0.4 1.1 1 0 0 1 1 1 0 EpsG family PilX_N PF14341.1 EMD58172.1 - 0.54 9.9 3.7 0.28 10.8 0.3 2.3 2 0 0 2 2 2 0 PilX N-terminal Methyltransf_2 PF00891.13 EMD58174.1 - 1.3e-33 116.2 0.0 2.1e-33 115.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Thioesterase PF00975.15 EMD58175.1 - 9e-22 78.4 0.0 9.5e-21 75.0 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMD58175.1 - 9e-09 35.5 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD58175.1 - 2.5e-07 30.5 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EMD58175.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EMD58175.1 - 0.005 16.4 0.1 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMD58175.1 - 0.006 16.0 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EMD58175.1 - 0.018 14.6 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Drf_FH1 PF06346.7 EMD58176.1 - 0.047 13.2 0.7 0.053 13.0 0.5 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 CD4-extracel PF09191.5 EMD58176.1 - 0.083 12.9 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 CD4, extracellular HTH_29 PF13551.1 EMD58178.1 - 3.6e-08 33.5 0.2 4.6e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EMD58178.1 - 1.3e-06 27.8 0.1 2.4e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EMD58178.1 - 5.5e-05 22.4 0.3 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EMD58178.1 - 6.7e-05 22.3 1.2 0.00014 21.3 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.3 EMD58178.1 - 7.6e-05 22.2 0.2 0.0002 20.9 0.0 1.7 2 0 0 2 2 2 1 Tc3 transposase Sigma70_r4_2 PF08281.7 EMD58178.1 - 7.7e-05 22.0 1.0 8.3e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.1 EMD58178.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 EMD58178.1 - 0.00019 21.0 0.0 0.00053 19.5 0.0 1.7 1 1 1 2 2 2 1 HTH domain HTH_Mga PF08280.6 EMD58178.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain PAX PF00292.13 EMD58178.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.0 1 0 0 1 1 1 0 'Paired box' domain HTH_7 PF02796.10 EMD58178.1 - 0.023 14.5 0.6 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.17 EMD58178.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_32 PF13565.1 EMD58178.1 - 0.029 15.1 0.5 0.29 11.9 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 EMD58178.1 - 0.032 13.7 1.5 6 6.4 0.0 2.6 2 1 1 3 3 3 0 AsnC-type helix-turn-helix domain FeoC PF09012.5 EMD58178.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator SgrR_N PF12793.2 EMD58178.1 - 0.042 13.8 0.3 0.081 12.9 0.1 1.5 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term HTH_Crp_2 PF13545.1 EMD58178.1 - 0.05 13.4 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EMD58178.1 - 0.05 12.9 0.2 0.093 12.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.2 EMD58178.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 MarR family Utp14 PF04615.8 EMD58179.1 - 0.033 12.3 0.1 0.039 12.1 0.1 1.1 1 0 0 1 1 1 0 Utp14 protein HrpJ PF07201.6 EMD58179.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 HrpJ-like domain DUF3716 PF12511.3 EMD58181.1 - 4e-08 32.7 4.4 8.4e-08 31.7 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Methyltransf_25 PF13649.1 EMD58182.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos_2 PF14529.1 EMD58183.1 - 1.5e-16 60.0 0.4 1.6e-16 59.9 0.3 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CAP PF00188.21 EMD58184.1 - 0.063 13.7 1.4 0.63 10.5 0.3 2.4 2 0 0 2 2 2 0 Cysteine-rich secretory protein family DUF2229 PF09989.4 EMD58184.1 - 0.2 11.1 1.9 0.4 10.1 1.3 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2894 PF11445.3 EMD58184.1 - 0.64 10.2 14.2 2.6 8.2 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) zf-CCHC PF00098.18 EMD58185.1 - 0.0075 16.1 2.9 0.011 15.5 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle NDUFB10 PF10249.4 EMD58185.1 - 0.042 14.0 0.2 0.044 13.9 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 zf-CCHC_5 PF14787.1 EMD58185.1 - 0.31 10.5 3.2 0.57 9.7 2.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HemY_N PF07219.8 EMD58185.1 - 0.42 10.1 3.5 0.51 9.9 2.4 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DOR PF14839.1 EMD58185.1 - 5.9 6.5 6.1 8.4 6.0 4.2 1.3 1 1 0 1 1 1 0 DOR family zf-CCHC PF00098.18 EMD58188.1 - 6.8e-09 35.2 7.0 1.3e-05 24.8 1.4 3.2 2 0 0 2 2 2 2 Zinc knuckle WCCH PF03716.9 EMD58188.1 - 0.02 14.3 0.1 0.02 14.3 0.1 4.0 4 0 0 4 4 4 0 WCCH motif Zn_clus PF00172.13 EMD58191.1 - 7.5e-05 22.5 4.1 0.00012 21.9 2.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2072 PF09845.4 EMD58191.1 - 0.0074 16.2 2.5 0.0083 16.0 1.7 1.1 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) APG6 PF04111.7 EMD58191.1 - 0.048 12.7 1.2 0.045 12.7 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3997 PF13162.1 EMD58193.1 - 0.11 12.3 0.2 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) HemY_N PF07219.8 EMD58195.1 - 0.34 10.4 2.6 0.34 10.4 1.8 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Arginase PF00491.16 EMD58196.1 - 0.031 13.5 0.0 0.035 13.3 0.0 1.0 1 0 0 1 1 1 0 Arginase family DUF58 PF01882.13 EMD58196.1 - 0.17 12.0 0.3 0.44 10.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF58 Amastin PF07344.6 EMD58197.1 - 0.0068 16.0 1.8 0.0079 15.8 0.2 1.9 1 1 1 2 2 2 1 Amastin surface glycoprotein HTH_Tnp_Tc3_2 PF01498.13 EMD58198.1 - 1.6e-08 34.5 0.1 2.2e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Transposase Zn_clus PF00172.13 EMD58201.1 - 5.8e-10 38.9 13.4 1.6e-09 37.5 9.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 EMD58202.1 - 4.8e-24 84.7 0.0 5.6e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Cupin_5 PF06172.6 EMD58202.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily (DUF985) DDE_3 PF13358.1 EMD58202.1 - 0.047 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_1 PF03184.14 EMD58203.1 - 1.4e-49 168.1 0.0 2e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD58203.1 - 2.9e-09 36.8 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF3g PF12353.3 EMD58204.1 - 0.84 9.5 8.5 2.8 7.8 1.6 2.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Condensation PF00668.15 EMD58205.1 - 6.7e-22 77.7 0.0 8.8e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EMD58206.1 - 3.2e-10 40.1 0.1 6.1e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EMD58206.1 - 3.4e-08 32.3 0.0 5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD58206.1 - 4.8e-07 30.6 0.0 8.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF979 PF06166.7 EMD58208.1 - 0.061 12.2 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Dimer_Tnp_hAT PF05699.9 EMD58212.1 - 1.2e-17 63.2 0.1 1.3e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Condensation PF00668.15 EMD58213.1 - 1.5e-201 667.5 0.0 3.6e-46 157.3 0.0 6.3 6 0 0 6 6 6 5 Condensation domain AMP-binding PF00501.23 EMD58213.1 - 4.8e-176 585.2 0.0 5.3e-79 265.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.20 EMD58213.1 - 2.5e-33 114.1 0.0 3.6e-08 33.5 0.0 6.1 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD58213.1 - 5.5e-14 52.8 0.1 0.0029 18.5 0.0 4.3 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 EMD58213.1 - 5.1e-06 25.3 1.8 0.0021 16.6 0.0 3.8 4 0 0 4 4 4 2 Alcohol acetyltransferase AMP-binding PF00501.23 EMD58214.1 - 2.8e-07 29.2 0.1 3.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD58214.1 - 0.00045 21.1 0.0 0.0007 20.5 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain MCR_beta_N PF02783.10 EMD58214.1 - 0.012 15.1 0.1 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain PP-binding PF00550.20 EMD58215.1 - 2.6e-05 24.3 0.1 4.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PNP_UDP_1 PF01048.15 EMD58218.1 - 9.3e-15 54.2 0.3 1.5e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 EMD58218.1 - 5.7e-13 49.0 0.0 5.8e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.7 EMD58218.1 - 3.1e-10 39.9 0.0 1.3e-09 37.9 0.0 2.0 2 1 0 2 2 2 1 NACHT domain Ank PF00023.25 EMD58218.1 - 2.3e-09 36.6 0.4 9e-05 22.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMD58218.1 - 6.7e-09 35.7 0.8 0.0014 18.7 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD58218.1 - 8e-09 35.7 0.1 4.6e-05 23.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EMD58218.1 - 7.1e-08 32.6 0.0 4.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 EMD58218.1 - 1.3e-07 31.1 0.0 0.14 12.4 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Arch_ATPase PF01637.13 EMD58218.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EMD58218.1 - 0.004 16.1 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMD58218.1 - 0.011 15.9 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EMD58218.1 - 0.014 14.3 0.2 0.69 8.8 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain DUF4129 PF13559.1 EMD58218.1 - 0.15 12.0 3.3 4.4 7.3 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4129) Ank_2 PF12796.2 EMD58219.1 - 5.1e-30 103.6 0.9 6.8e-13 48.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD58219.1 - 1.2e-26 92.5 3.0 4.7e-11 42.9 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD58219.1 - 7.3e-25 85.5 2.8 1.9e-08 33.6 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EMD58219.1 - 4.6e-19 66.5 0.1 1.7e-05 24.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMD58219.1 - 2.4e-18 65.7 0.3 3.7e-09 36.5 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Trp_DMAT PF11991.3 EMD58220.1 - 6e-118 394.1 0.0 7.2e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Pyr_redox_3 PF13738.1 EMD58221.1 - 5.8e-19 68.9 0.0 5.6e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD58221.1 - 2.7e-05 23.2 0.0 0.0056 15.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EMD58221.1 - 2.7e-05 22.5 0.0 0.00023 19.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EMD58221.1 - 0.0018 18.3 0.0 0.007 16.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EMD58221.1 - 0.0037 17.2 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMD58221.1 - 0.0096 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EMD58221.1 - 0.032 14.1 0.0 13 5.5 0.0 2.5 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMD58221.1 - 0.17 12.1 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding WD40 PF00400.27 EMD58222.1 - 2.9e-176 565.8 44.9 4.4e-14 51.7 0.0 15.2 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 EMD58222.1 - 4.3e-24 84.5 26.8 0.0037 15.4 0.2 11.7 1 1 11 12 12 12 9 Nucleoporin Nup120/160 eIF2A PF08662.6 EMD58222.1 - 6.5e-17 61.8 0.0 0.049 13.3 0.0 5.8 1 1 4 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EMD58222.1 - 1.3e-16 59.8 1.4 0.89 9.2 0.0 12.2 15 0 0 15 15 14 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EMD58222.1 - 9.9e-15 53.5 0.0 1.8 7.9 0.0 11.0 11 0 0 11 11 11 2 Proteasome subunit A N-terminal signature DUF1513 PF07433.6 EMD58222.1 - 9.9e-11 41.0 16.1 0.023 13.6 0.1 7.0 1 1 7 8 8 8 3 Protein of unknown function (DUF1513) NACHT PF05729.7 EMD58222.1 - 2.7e-07 30.4 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TruB_C PF09142.6 EMD58222.1 - 1.1e-06 28.1 6.8 96 2.7 0.0 10.1 11 0 0 11 11 10 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.7 EMD58222.1 - 1.5e-06 26.3 6.5 0.66 7.7 0.1 5.4 1 1 1 3 3 3 3 IKI3 family AAA_16 PF13191.1 EMD58222.1 - 1.8e-06 28.0 0.1 1.8e-06 28.0 0.1 3.3 3 1 0 3 3 2 1 AAA ATPase domain DUF1652 PF07865.6 EMD58222.1 - 0.00013 21.4 1.8 12 5.6 0.0 6.7 8 1 1 9 9 5 0 Protein of unknown function (DUF1652) DUF1258 PF06869.7 EMD58222.1 - 0.00028 20.0 9.2 24 3.8 0.0 8.9 1 1 11 12 12 12 0 Protein of unknown function (DUF1258) NB-ARC PF00931.17 EMD58222.1 - 0.0005 19.0 0.0 0.00093 18.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EMD58222.1 - 0.002 18.3 0.1 0.0063 16.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD58222.1 - 0.0021 18.2 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 EMD58222.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase PhoH PF02562.11 EMD58222.1 - 0.01 15.1 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein APS_kinase PF01583.15 EMD58222.1 - 0.023 14.3 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EMD58222.1 - 0.023 14.4 0.0 0.09 12.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EMD58222.1 - 0.045 14.5 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMD58222.1 - 0.055 13.0 0.2 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 EMD58222.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Syntaxin RNA_helicase PF00910.17 EMD58222.1 - 0.13 12.4 0.1 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DDE_3 PF13358.1 EMD58223.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CCDC-167 PF15188.1 EMD58223.1 - 0.11 12.4 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_10 PF13374.1 EMD58224.1 - 5.1e-63 207.3 2.5 3.7e-13 48.9 0.0 6.4 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMD58224.1 - 3.4e-49 164.6 1.9 1.4e-14 53.7 0.0 5.3 1 1 4 5 5 5 5 Tetratricopeptide repeat HET PF06985.6 EMD58224.1 - 2.6e-20 73.0 12.7 2.9e-18 66.3 7.9 3.4 2 1 0 2 2 1 1 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.1 EMD58224.1 - 9.5e-15 53.1 0.6 0.038 13.8 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 EMD58224.1 - 1.5e-14 53.5 0.0 2.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EMD58224.1 - 5.1e-10 38.5 1.8 1.2 9.2 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMD58224.1 - 2.1e-09 36.8 0.1 0.44 11.1 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58224.1 - 1.1e-08 34.6 0.0 0.0094 15.5 0.0 4.0 3 1 0 3 3 3 2 TPR repeat AAA_16 PF13191.1 EMD58224.1 - 3.1e-08 33.8 2.4 5e-08 33.1 0.3 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD58224.1 - 5.9e-08 32.9 0.1 2.8e-07 30.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain TPR_16 PF13432.1 EMD58224.1 - 6.8e-07 29.8 0.0 0.0096 16.5 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD58224.1 - 7.1e-07 28.9 1.5 8.2 6.9 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMD58224.1 - 3.6e-05 24.0 0.1 0.15 12.4 0.0 4.2 3 1 2 5 5 4 1 Tetratricopeptide repeat NACHT PF05729.7 EMD58224.1 - 7.9e-05 22.3 0.1 0.0002 21.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EMD58224.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EMD58224.1 - 0.00011 22.3 0.0 0.0005 20.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_8 PF13181.1 EMD58224.1 - 0.00025 20.5 0.1 14 5.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58224.1 - 0.00027 20.4 0.5 14 5.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 EMD58224.1 - 0.0013 18.1 0.0 0.0047 16.3 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TPR_6 PF13174.1 EMD58224.1 - 0.0017 18.6 3.9 34 5.1 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD58224.1 - 0.0022 18.0 0.4 4.1 7.5 0.0 4.8 2 1 3 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMD58224.1 - 0.0036 17.8 2.6 90 4.1 0.0 5.6 7 0 0 7 7 4 0 Tetratricopeptide repeat AAA_25 PF13481.1 EMD58224.1 - 0.0079 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EMD58224.1 - 0.074 12.4 0.1 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EMD58224.1 - 0.08 13.7 0.0 0.29 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain DDE_1 PF03184.14 EMD58226.1 - 1.9e-14 53.3 0.0 2.1e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease ATE_N PF04376.8 EMD58226.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus DDE_3 PF13358.1 EMD58226.1 - 0.12 12.0 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease ATP_transf PF09830.4 EMD58227.1 - 2.9e-11 42.9 0.0 6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase WD40 PF00400.27 EMD58228.1 - 3.4e-151 486.4 82.4 5.6e-15 54.5 1.1 13.2 12 1 1 13 13 13 12 WD domain, G-beta repeat NACHT PF05729.7 EMD58228.1 - 2.9e-18 66.0 0.2 5.9e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD58228.1 - 1.3e-16 59.8 40.9 0.1 10.6 0.1 11.2 2 1 10 12 12 12 11 Nucleoporin Nup120/160 Nbas_N PF15492.1 EMD58228.1 - 1.7e-11 43.7 26.2 0.35 9.9 0.1 9.9 2 2 9 11 11 11 7 Neuroblastoma-amplified sequence, N terminal CDtoxinA PF03498.9 EMD58228.1 - 1.3e-10 40.8 0.1 2.3 7.5 0.0 7.4 2 2 4 6 6 6 4 Cytolethal distending toxin A/C family Asp_decarbox PF02261.11 EMD58228.1 - 2.1e-09 36.9 0.0 15 5.2 0.0 8.7 3 2 6 9 9 9 2 Aspartate decarboxylase AAA_19 PF13245.1 EMD58228.1 - 0.09 12.5 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TPR_12 PF13424.1 EMD58229.1 - 4.9e-15 55.2 0.9 4.1e-11 42.6 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD58229.1 - 3.3e-14 52.2 1.0 2e-07 30.7 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD58229.1 - 0.00065 19.3 0.2 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Rab5-bind PF09311.6 EMD58229.1 - 0.0036 17.2 0.2 0.004 17.0 0.1 1.1 1 0 0 1 1 1 1 Rabaptin-like protein TPR_2 PF07719.12 EMD58229.1 - 0.035 14.0 0.8 0.91 9.5 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58229.1 - 0.037 13.6 0.4 10 5.9 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58229.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.9 1 1 0 1 1 1 0 TPR repeat zf-C2H2_jaz PF12171.3 EMD58230.1 - 3.6e-13 49.2 11.7 0.013 15.5 0.1 4.5 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD58230.1 - 3.3e-10 39.9 13.6 0.014 15.4 0.2 4.3 1 1 3 4 4 4 4 C2H2 type zinc-finger (2 copies) RRN7 PF11781.3 EMD58230.1 - 5.6e-06 25.7 0.3 8 6.0 0.0 4.1 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 EMD58230.1 - 5.2e-05 23.3 14.7 1.8 8.8 0.2 4.7 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMD58230.1 - 0.0002 21.4 7.7 11 6.5 0.0 4.6 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD58230.1 - 0.00023 21.3 19.2 1.1 9.7 0.2 4.8 6 0 0 6 6 4 4 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EMD58230.1 - 0.00033 20.2 5.7 5.9 6.6 0.1 4.2 4 0 0 4 4 4 1 zinc-finger of a C2HC-type Prok-RING_1 PF14446.1 EMD58230.1 - 0.00034 20.2 7.7 7.5 6.3 0.0 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF4428 PF14471.1 EMD58230.1 - 0.00072 19.2 11.2 3.8 7.3 0.1 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4428) TF_Zn_Ribbon PF08271.7 EMD58230.1 - 0.0094 15.2 2.5 42 3.5 0.0 4.0 4 0 0 4 4 4 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 EMD58230.1 - 0.02 15.1 20.0 5.9 7.3 0.8 4.3 4 0 0 4 4 4 0 Zinc-finger double domain C1_1 PF00130.17 EMD58230.1 - 0.035 13.8 4.9 4 7.2 0.2 3.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lipoprotein_15 PF03640.10 EMD58230.1 - 0.081 12.3 1.6 37 3.8 0.0 3.7 4 0 0 4 4 4 0 Secreted repeat of unknown function HypA PF01155.14 EMD58230.1 - 0.2 11.3 6.2 1.5 8.4 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-DNA_Pol PF08996.5 EMD58230.1 - 0.2 10.9 6.3 1.3 8.3 0.6 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Laminin_EGF PF00053.19 EMD58230.1 - 0.21 11.5 7.8 32 4.5 0.1 4.1 4 0 0 4 4 4 0 Laminin EGF-like (Domains III and V) zf-AN1 PF01428.11 EMD58230.1 - 0.29 11.0 10.4 42 4.1 0.1 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger C1_4 PF07975.7 EMD58230.1 - 0.64 10.0 11.5 6 6.9 1.4 2.8 1 1 3 4 4 4 0 TFIIH C1-like domain zf-C3HC4_2 PF13923.1 EMD58230.1 - 0.64 10.0 11.4 32 4.6 0.1 4.2 1 1 3 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF629 PF04780.7 EMD58230.1 - 1.3 7.4 9.0 14 4.0 0.9 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF629) GFA PF04828.9 EMD58230.1 - 1.4 8.8 10.3 19 5.2 0.1 3.6 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Evr1_Alr PF04777.8 EMD58230.1 - 2.4 8.1 15.7 13 5.7 0.2 4.1 1 1 3 4 4 4 0 Erv1 / Alr family E6 PF00518.12 EMD58230.1 - 4.1 7.8 5.8 2 8.7 0.0 3.0 1 1 3 4 4 4 0 Early Protein (E6) zf-trcl PF13451.1 EMD58230.1 - 8.2 6.1 10.4 97 2.7 0.1 3.9 4 0 0 4 4 4 0 Probable zinc-binding domain Cytochrome_C7 PF14522.1 EMD58230.1 - 8.8 6.0 16.5 35 4.1 6.2 2.7 1 1 1 2 2 2 0 Cytochrome c7 Abhydrolase_6 PF12697.2 EMD58231.1 - 4.9e-07 29.8 0.0 6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD58231.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMD58231.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EMD58231.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_10 PF13374.1 EMD58233.1 - 2.9e-88 287.6 33.0 2.5e-11 43.1 0.1 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 EMD58233.1 - 2.7e-77 254.7 51.3 1.9e-18 66.1 1.4 7.7 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58233.1 - 5.4e-42 139.7 43.2 3.9e-05 23.0 0.1 11.4 11 1 0 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMD58233.1 - 3.7e-31 104.4 41.7 0.00082 18.9 0.1 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58233.1 - 5.9e-30 102.7 36.0 2.2e-08 33.6 1.0 7.1 4 2 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 EMD58233.1 - 2.9e-27 92.3 40.5 0.0083 15.9 0.3 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 EMD58233.1 - 4.4e-23 79.2 28.9 0.016 14.9 0.2 9.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMD58233.1 - 6e-20 69.9 34.2 0.087 13.5 0.0 11.3 7 2 3 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMD58233.1 - 2.6e-15 56.5 50.3 0.00024 21.6 2.9 7.4 4 3 5 9 9 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EMD58233.1 - 4.2e-14 51.5 23.5 1.1 9.6 0.0 9.9 8 1 1 9 9 8 7 Tetratricopeptide repeat TPR_4 PF07721.9 EMD58233.1 - 4.1e-12 45.3 5.2 1.6 9.3 0.0 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD58233.1 - 2.5e-10 39.6 0.0 7.1e-09 34.9 0.0 2.2 1 1 1 2 2 2 1 NB-ARC domain DUF2225 PF09986.4 EMD58233.1 - 3.2e-10 39.8 17.2 0.021 14.2 0.2 6.2 1 1 6 7 7 7 5 Uncharacterized protein conserved in bacteria (DUF2225) AAA_16 PF13191.1 EMD58233.1 - 6.3e-10 39.3 0.3 4.5e-09 36.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RPN7 PF10602.4 EMD58233.1 - 2.7e-06 26.8 9.9 6.9 6.0 0.0 7.1 2 2 4 7 7 7 0 26S proteasome subunit RPN7 14-3-3 PF00244.15 EMD58233.1 - 6.9e-06 25.3 4.3 4.6 6.2 0.0 5.3 2 1 3 6 6 6 1 14-3-3 protein TPR_3 PF07720.7 EMD58233.1 - 9.5e-06 25.3 30.8 1.2 9.0 0.2 9.5 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMD58233.1 - 0.00058 20.1 45.2 3.6 8.2 0.1 10.0 9 0 0 9 9 9 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EMD58233.1 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EMD58233.1 - 0.0051 16.9 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.1 EMD58233.1 - 0.013 15.8 37.4 1.2 9.5 1.0 7.6 5 2 4 9 9 8 0 Tetratricopeptide repeat NACHT PF05729.7 EMD58233.1 - 0.055 13.1 0.1 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 NACHT domain rve_3 PF13683.1 EMD58233.1 - 0.068 12.6 0.1 9.3 5.8 0.1 3.0 2 0 0 2 2 2 0 Integrase core domain AA_kinase PF00696.23 EMD58233.1 - 0.13 11.7 0.0 2.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Amino acid kinase family DUF3366 PF11846.3 EMD58233.1 - 0.82 9.5 23.6 17 5.2 0.2 7.0 1 1 6 7 7 7 0 Domain of unknown function (DUF3366) Prefoldin_3 PF13758.1 EMD58236.1 - 0.076 12.7 0.2 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF1889 PF08986.5 EMD58237.1 - 0.017 15.3 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) DUF3632 PF12311.3 EMD58238.1 - 1.9e-26 93.0 0.1 2.5e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF2222 PF09984.4 EMD58238.1 - 0.13 11.6 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) HTH_psq PF05225.11 EMD58239.1 - 1.2e-06 27.9 0.7 1.4e-06 27.6 0.2 1.4 1 1 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 EMD58239.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain BrkDBD PF09607.5 EMD58239.1 - 0.066 12.7 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Brinker DNA-binding domain Cyc-maltodext_C PF10438.4 EMD58239.1 - 0.086 12.9 0.1 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Condensation PF00668.15 EMD58240.1 - 1.8e-82 276.5 0.0 1.7e-44 151.9 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.23 EMD58240.1 - 1.9e-82 276.9 3.4 1.4e-59 201.5 2.3 3.0 3 0 0 3 3 3 2 AMP-binding enzyme PP-binding PF00550.20 EMD58240.1 - 3.6e-13 49.5 0.0 1e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD58240.1 - 0.00026 21.8 0.8 0.0013 19.5 0.6 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EMD58241.1 - 1.4e-38 132.3 0.7 1.6e-38 132.2 0.5 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EMD58242.1 - 3.9e-36 124.4 0.4 9.9e-36 123.1 0.2 1.7 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.23 EMD58243.1 - 1.5e-127 425.4 0.9 1.2e-84 284.1 0.1 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EMD58243.1 - 8.2e-58 195.6 0.4 1.2e-57 195.0 0.3 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EMD58243.1 - 1.5e-30 105.2 0.0 1.4e-13 50.9 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EMD58243.1 - 2.8e-24 85.2 0.2 1.2e-23 83.2 0.1 2.2 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EMD58243.1 - 1.5e-16 61.0 3.2 0.00075 20.4 0.0 4.5 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 EMD58243.1 - 5.6e-05 22.9 0.0 0.0027 17.4 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD58243.1 - 6.3e-05 23.2 0.0 0.00037 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD58243.1 - 0.00016 22.2 0.0 0.003 18.0 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD58243.1 - 0.0034 16.9 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD58243.1 - 0.0048 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD58243.1 - 0.0057 16.6 0.1 0.04 13.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Condensation PF00668.15 EMD58244.1 - 2.6e-43 148.0 0.0 3.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Trp_DMAT PF11991.3 EMD58245.1 - 6.5e-91 305.2 0.0 8e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Ank_5 PF13857.1 EMD58246.1 - 2.2e-12 46.7 0.0 3.7e-07 30.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD58246.1 - 8.3e-09 35.6 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD58246.1 - 1.2e-07 31.1 0.0 0.023 14.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMD58246.1 - 1.1e-06 28.9 0.0 8.7e-05 22.9 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 EMD58246.1 - 0.00061 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 EMD58246.1 - 0.0028 17.7 0.0 3.1 8.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat DDE_1 PF03184.14 EMD58248.1 - 7.6e-27 93.8 0.0 1.5e-20 73.2 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EMD58248.1 - 0.052 13.2 0.0 0.098 12.4 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease WD40 PF00400.27 EMD58249.1 - 3.9e-76 248.4 28.3 8.2e-14 50.8 0.4 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 EMD58249.1 - 9.9e-30 103.3 0.1 4.7e-29 101.1 0.1 2.0 2 0 0 2 2 2 1 NACHT domain HET PF06985.6 EMD58249.1 - 3.5e-21 75.8 5.1 1.4e-19 70.6 3.5 3.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD58249.1 - 2.1e-07 29.4 21.3 0.11 10.6 0.3 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EMD58249.1 - 0.00027 20.3 0.0 0.015 14.7 0.0 2.7 2 0 0 2 2 2 1 Cytolethal distending toxin A/C family Asp_decarbox PF02261.11 EMD58249.1 - 0.0027 17.2 0.0 23 4.6 0.0 4.4 2 1 2 4 4 4 0 Aspartate decarboxylase AAA_19 PF13245.1 EMD58249.1 - 0.029 14.1 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Cytochrom_D1 PF02239.11 EMD58249.1 - 0.044 12.0 0.8 3.8 5.6 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.27 EMD58250.1 - 2.7e-164 527.9 85.1 7.3e-14 51.0 1.0 14.3 15 0 0 15 15 15 13 WD domain, G-beta repeat NACHT PF05729.7 EMD58250.1 - 3.2e-24 85.4 0.1 1.2e-23 83.6 0.1 1.9 2 0 0 2 2 2 1 NACHT domain HET PF06985.6 EMD58250.1 - 2.6e-21 76.2 7.9 5.2e-21 75.2 3.2 3.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD58250.1 - 9.3e-21 73.5 49.7 0.004 15.3 0.1 12.4 1 1 10 11 11 11 10 Nucleoporin Nup120/160 Asp_decarbox PF02261.11 EMD58250.1 - 5e-08 32.5 0.0 2.4 7.7 0.0 8.4 2 2 5 10 10 10 1 Aspartate decarboxylase SRP9-21 PF05486.7 EMD58250.1 - 2.4e-05 23.9 0.1 38 4.1 0.0 8.1 9 1 0 9 9 9 0 Signal recognition particle 9 kDa protein (SRP9) AAA_19 PF13245.1 EMD58250.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain IF2_assoc PF08364.6 EMD58250.1 - 0.05 13.6 5.7 57 3.8 0.0 4.8 4 0 0 4 4 4 0 Bacterial translation initiation factor IF-2 associated region Cytochrom_D1 PF02239.11 EMD58250.1 - 0.38 8.9 9.0 5 5.3 0.1 3.9 2 1 4 6 6 6 0 Cytochrome D1 heme domain DDE_1 PF03184.14 EMD58251.1 - 0.019 14.0 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease p450 PF00067.17 EMD58252.1 - 5.2e-74 249.4 0.0 6.4e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wax2_C PF12076.3 EMD58252.1 - 0.047 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain NLPC_P60 PF00877.14 EMD58253.1 - 2e-10 40.4 0.5 3.2e-10 39.7 0.4 1.3 1 0 0 1 1 1 1 NlpC/P60 family AA_permease PF00324.16 EMD58255.1 - 3.4e-16 58.6 19.2 6.5e-16 57.7 13.3 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD58255.1 - 3.2e-11 42.4 14.8 4.9e-11 41.8 10.3 1.3 1 0 0 1 1 1 1 Amino acid permease CorA PF01544.13 EMD58257.1 - 9.7e-05 21.5 5.8 0.00021 20.4 4.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.17 EMD58259.1 - 1.6e-15 57.0 0.1 2.9e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EMD58259.1 - 8.5e-07 29.2 5.5 1.8e-05 24.9 0.9 3.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD58259.1 - 7.1e-05 23.2 0.2 0.19 12.3 0.0 4.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 EMD58259.1 - 0.00012 21.7 0.4 0.05 13.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMD58259.1 - 0.0082 16.3 0.2 1.7 9.0 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD58262.1 - 2.8e-52 174.9 5.1 8.6e-17 61.2 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMD58262.1 - 1.9e-41 137.8 10.3 6.6e-08 31.9 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EMD58262.1 - 5.7e-37 125.4 4.1 8.6e-11 42.0 0.0 6.2 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD58262.1 - 4.1e-36 119.4 1.5 2.7e-06 27.0 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EMD58262.1 - 7.5e-36 121.3 13.3 2e-07 30.9 0.0 7.8 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EMD58262.1 - 0.0049 16.4 0.3 0.64 9.4 0.0 2.9 3 0 0 3 3 3 1 Shigella flexneri OspC protein PPR_3 PF13812.1 EMD58262.1 - 0.095 13.0 0.4 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain p450 PF00067.17 EMD58263.1 - 2.1e-31 108.9 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EMD58264.1 - 8.6e-15 54.1 0.0 2.6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 Transferase family p450 PF00067.17 EMD58265.1 - 2.4e-58 197.7 0.0 3e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 EMD58266.1 - 7.5e-13 48.8 1.0 8.4e-05 22.9 0.1 3.9 3 0 0 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMD58266.1 - 7.8e-07 29.0 0.3 0.02 14.9 0.0 3.7 3 0 0 3 3 3 2 Prenyltransferase-like Terpene_synth_C PF03936.11 EMD58266.1 - 0.00012 21.4 1.5 0.0087 15.3 0.0 3.4 2 2 1 3 3 3 1 Terpene synthase family, metal binding domain Prenyltrans PF00432.16 EMD58266.1 - 0.0014 18.0 2.6 0.03 13.8 0.0 3.9 4 0 0 4 4 4 1 Prenyltransferase and squalene oxidase repeat Aldedh PF00171.17 EMD58267.1 - 2.4e-133 444.8 0.0 2.7e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD58267.1 - 0.015 14.0 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cupin_2 PF07883.6 EMD58268.1 - 1.4e-13 50.1 1.1 1.9e-13 49.6 0.8 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMD58268.1 - 3.3e-07 30.0 0.1 4.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 EMD58268.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EMD58268.1 - 0.0057 16.3 0.5 0.0077 15.9 0.3 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EMD58268.1 - 0.0073 15.6 0.2 0.027 13.8 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF861) p450 PF00067.17 EMD58269.1 - 2e-43 148.6 0.0 2.6e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APT PF03440.9 EMD58269.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Methyltransf_16 PF10294.4 EMD58270.1 - 3.3e-15 55.9 0.0 5.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMD58270.1 - 7.3e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD58270.1 - 0.0031 16.9 0.1 0.0071 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMD58270.1 - 0.021 15.3 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMD58270.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMD58270.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_43 PF04616.9 EMD58271.1 - 2.3e-13 49.8 2.0 3.9e-13 49.1 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pectate_lyase PF03211.8 EMD58272.1 - 1.1e-55 188.4 4.8 1.5e-55 187.9 3.3 1.1 1 0 0 1 1 1 1 Pectate lyase Utp11 PF03998.8 EMD58273.1 - 1.1e-67 228.3 33.9 1.3e-67 228.1 23.5 1.0 1 0 0 1 1 1 1 Utp11 protein DUF2250 PF10007.4 EMD58273.1 - 8.9 6.3 9.9 3.7 7.5 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) adh_short PF00106.20 EMD58274.1 - 5.6e-24 84.9 1.6 7.5e-24 84.5 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD58274.1 - 3.8e-12 46.2 1.7 8.4e-12 45.1 1.1 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD58274.1 - 1.9e-09 37.6 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cmc1 PF08583.5 EMD58275.1 - 8.9e-16 57.4 4.1 1.7e-15 56.5 2.9 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EMD58275.1 - 0.032 14.2 0.5 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2773 PF10971.3 EMD58275.1 - 0.05 13.5 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Selenoprotein_S PF06936.6 EMD58275.1 - 0.33 10.4 4.9 0.41 10.1 3.4 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) TFIID-31kDa PF02291.10 EMD58276.1 - 3.4e-35 120.6 0.0 8.3e-35 119.3 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit fn3 PF00041.16 EMD58277.1 - 6.3e-06 26.2 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.8 EMD58278.1 - 4.8e-70 234.1 0.0 8e-70 233.4 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EMD58278.1 - 1.4e-38 130.9 0.0 3.1e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EMD58278.1 - 0.0066 15.8 0.3 0.061 12.6 0.0 2.5 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) FPN1 PF06963.7 EMD58279.1 - 4.3e-138 460.3 10.8 5.1e-138 460.0 7.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) AflR PF08493.5 EMD58280.1 - 1.3e-11 44.1 0.8 1.3e-11 44.1 0.5 2.1 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EMD58280.1 - 7.1e-09 35.4 13.0 7.1e-09 35.4 9.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 EMD58284.1 - 3.3e-61 207.6 0.7 4.1e-61 207.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD58284.1 - 0.00017 21.5 34.7 0.0015 18.4 10.6 3.4 3 0 0 3 3 3 2 Chitin recognition protein Reprolysin_4 PF13583.1 EMD58284.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Polyketide_cyc PF03364.15 EMD58285.1 - 0.049 13.6 0.5 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport PAN_4 PF14295.1 EMD58286.1 - 0.036 13.7 4.2 0.072 12.8 0.3 2.7 2 0 0 2 2 2 0 PAN domain AAA_16 PF13191.1 EMD58287.1 - 0.00022 21.2 0.6 0.014 15.4 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EMD58287.1 - 0.0021 17.8 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EMD58287.1 - 0.13 11.1 0.0 0.32 9.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) F-box-like PF12937.2 EMD58288.1 - 4.7e-14 51.8 1.0 8.7e-14 50.9 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD58288.1 - 3.1e-09 36.2 0.8 7.8e-09 34.9 0.6 1.7 1 0 0 1 1 1 1 F-box domain Reg_prop PF07494.6 EMD58288.1 - 0.15 12.1 1.2 5.4 7.3 0.2 3.1 2 0 0 2 2 2 0 Two component regulator propeller SKG6 PF08693.5 EMD58289.1 - 5e-05 22.5 0.1 9.9e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EMD58289.1 - 0.00086 18.7 0.1 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 EMD58289.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain KAR9 PF08580.5 EMD58289.1 - 8.5 4.5 6.1 11 4.1 4.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF3431 PF11913.3 EMD58290.1 - 1.1e-85 286.6 0.3 1.4e-85 286.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Asp PF00026.18 EMD58291.1 - 4.3e-05 22.9 7.0 0.094 11.9 3.6 2.5 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Profilin PF00235.14 EMD58296.1 - 1.1e-37 128.8 0.3 1.2e-37 128.7 0.2 1.0 1 0 0 1 1 1 1 Profilin PBP-Tp47_a PF14889.1 EMD58296.1 - 0.038 13.3 0.1 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Cag12 PF13117.1 EMD58296.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.3 1 1 0 1 1 1 0 Cag pathogenicity island protein Cag12 RRM_6 PF14259.1 EMD58297.1 - 5e-11 42.4 0.0 7.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD58297.1 - 1e-10 41.0 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD58297.1 - 6.1e-08 32.3 0.0 9.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD58297.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Pkinase PF00069.20 EMD58298.1 - 1.3e-67 227.6 0.0 3.1e-67 226.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58298.1 - 8.7e-30 103.6 0.5 1.4e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMD58298.1 - 0.00029 20.6 2.8 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD58298.1 - 0.00048 19.2 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMD58298.1 - 0.0027 17.0 0.1 0.0027 17.0 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EMD58298.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1679 PF07914.6 EMD58298.1 - 0.053 12.1 0.1 0.42 9.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) YrbL-PhoP_reg PF10707.4 EMD58298.1 - 0.12 11.7 0.8 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Methyltransf_28 PF02636.12 EMD58299.1 - 1.9e-72 243.7 0.0 2.2e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Anoctamin PF04547.7 EMD58300.1 - 1.1e-115 386.8 2.9 1.4e-115 386.5 2.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_membrane PF00664.18 EMD58300.1 - 0.044 13.1 0.0 0.044 13.1 0.0 2.5 3 0 0 3 3 3 0 ABC transporter transmembrane region PAP_assoc PF03828.14 EMD58301.1 - 1.8e-09 37.3 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMD58301.1 - 1.1e-05 25.5 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pam16 PF03656.8 EMD58302.1 - 7.7e-31 106.5 0.4 9e-31 106.3 0.3 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 EMD58303.1 - 1.1e-97 327.0 0.8 1.4e-97 326.7 0.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Amidase PF01425.16 EMD58304.1 - 2.1e-112 376.1 0.0 2.6e-112 375.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Bud13 PF09736.4 EMD58305.1 - 4.3e-46 156.7 12.1 4.3e-46 156.7 8.4 2.9 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.15 EMD58306.1 - 2.3e-20 72.1 0.3 8.3e-20 70.3 0.2 1.7 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_3 PF07859.8 EMD58308.1 - 4.9e-45 153.7 0.3 1.9e-30 106.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EMD58308.1 - 2.6e-08 33.0 0.0 3.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMD58308.1 - 0.0019 17.9 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD58308.1 - 0.013 14.7 0.0 0.49 9.5 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 EMD58308.1 - 0.094 12.1 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative esterase HET PF06985.6 EMD58309.1 - 3.4e-20 72.6 0.0 4.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EMD58313.1 - 8.3e-58 194.2 0.0 5e-43 146.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD58313.1 - 1.5e-11 44.6 1.3 0.0015 18.5 0.0 4.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 EMD58313.1 - 1.6e-11 44.1 0.0 7.2e-07 29.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD58313.1 - 4.5e-09 36.5 0.8 0.00038 20.6 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMD58313.1 - 2.4e-07 30.7 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EMD58313.1 - 7.1e-06 26.0 0.0 0.00076 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMD58313.1 - 1.8e-05 24.6 0.0 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMD58313.1 - 3.2e-05 23.9 0.1 0.059 13.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EMD58313.1 - 5.5e-05 23.9 0.5 0.4 11.5 0.0 3.6 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD58313.1 - 9.5e-05 21.5 0.1 0.0021 17.1 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMD58313.1 - 0.00011 21.8 0.1 0.072 12.8 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain NACHT PF05729.7 EMD58313.1 - 0.00012 21.7 0.2 0.37 10.4 0.0 3.9 3 1 1 4 4 4 1 NACHT domain Mg_chelatase PF01078.16 EMD58313.1 - 0.00021 20.4 0.1 0.54 9.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMD58313.1 - 0.00031 20.8 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EMD58313.1 - 0.00036 19.9 3.3 4.3 6.6 0.0 4.1 2 2 1 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EMD58313.1 - 0.00041 20.4 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EMD58313.1 - 0.00069 18.7 0.0 0.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EMD58313.1 - 0.00082 18.1 0.0 0.0082 14.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus KaiC PF06745.8 EMD58313.1 - 0.0015 17.7 0.0 0.075 12.1 0.0 2.7 2 1 0 2 2 2 1 KaiC CDC48_N PF02359.13 EMD58313.1 - 0.0021 17.9 0.0 0.0058 16.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Vps4_C PF09336.5 EMD58313.1 - 0.0023 17.7 0.1 1.2 9.0 0.0 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 EMD58313.1 - 0.0026 17.1 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 EMD58313.1 - 0.0092 15.7 0.0 5.7 6.5 0.0 3.0 2 1 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EMD58313.1 - 0.016 14.7 0.0 3.4 7.1 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EMD58313.1 - 0.038 13.6 0.0 2.3 7.8 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EMD58313.1 - 0.056 12.6 0.0 15 4.7 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein ATP-synt_ab PF00006.20 EMD58313.1 - 0.057 12.9 0.0 0.71 9.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AreA_N PF07573.6 EMD58314.1 - 0.42 11.1 4.5 6.7 7.3 1.2 2.4 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus EAP30 PF04157.11 EMD58315.1 - 1.1e-52 178.4 0.0 3.2e-52 176.8 0.0 1.6 1 1 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.6 EMD58316.1 - 3.8e-87 292.5 0.0 4.9e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein zf-LITAF-like PF10601.4 EMD58317.1 - 3.6e-24 84.4 7.8 4.6e-24 84.0 5.4 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 EMD58317.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 EMD58317.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.5 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 EMD58317.1 - 7.5 6.4 11.0 9.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PAP2 PF01569.16 EMD58318.1 - 1.1e-20 73.5 2.1 1.1e-20 73.5 1.4 1.9 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.1 EMD58318.1 - 0.067 13.4 0.7 0.067 13.4 0.5 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal AMP-binding PF00501.23 EMD58319.1 - 0 1096.1 0.0 1.4e-88 297.1 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EMD58319.1 - 3.4e-188 623.7 7.7 2.7e-40 138.0 0.0 6.3 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EMD58319.1 - 4e-54 180.7 8.8 1.2e-09 38.2 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD58319.1 - 1.8e-22 80.0 0.1 4.4e-06 27.5 0.0 5.5 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 EMD58320.1 - 4.6e-73 245.9 29.3 4.7e-37 127.8 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD58320.1 - 4.2e-68 227.9 0.0 1.5e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMD58320.1 - 6.1e-14 52.6 0.2 0.012 15.5 0.2 4.3 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EMD58320.1 - 2e-13 50.1 1.2 0.00058 19.1 0.0 4.5 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMD58320.1 - 3.2e-08 32.9 0.1 0.004 16.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EMD58320.1 - 6.9e-07 28.2 0.1 0.0053 15.3 0.0 2.8 3 1 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EMD58320.1 - 4.5e-06 25.9 0.0 0.084 12.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD58320.1 - 1.4e-05 25.1 5.4 0.065 13.2 0.7 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EMD58320.1 - 1.9e-05 24.1 0.1 0.028 13.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EMD58320.1 - 2.1e-05 25.3 0.0 0.0092 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMD58320.1 - 2.9e-05 23.2 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 EMD58320.1 - 0.00026 21.1 3.8 0.087 12.9 0.0 4.4 3 2 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EMD58320.1 - 0.00046 20.0 3.8 0.13 12.1 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EMD58320.1 - 0.00057 20.1 0.0 1.6 8.9 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMD58320.1 - 0.00095 19.0 0.0 0.22 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EMD58320.1 - 0.0016 18.1 0.0 0.85 9.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 EMD58320.1 - 0.0037 16.9 0.1 4 7.1 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EMD58320.1 - 0.0039 17.5 0.1 0.32 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMD58320.1 - 0.0054 16.4 0.0 0.41 10.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMD58320.1 - 0.0064 16.7 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMD58320.1 - 0.0069 15.8 0.1 4 6.7 0.1 2.9 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 EMD58320.1 - 0.0073 16.2 0.7 2.3 8.1 0.0 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EMD58320.1 - 0.011 15.4 0.1 0.47 10.2 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain DUF87 PF01935.12 EMD58320.1 - 0.078 12.7 0.2 6.1 6.6 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 K_oxygenase PF13434.1 EMD58321.1 - 1.1e-97 327.0 0.0 1.6e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD58321.1 - 1.9e-08 34.2 0.0 2.5e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD58321.1 - 7.4e-07 29.2 0.0 7.9e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD58321.1 - 1.5e-06 28.4 0.0 8.3e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 EMD58322.1 - 4e-52 176.9 0.0 8.4e-52 175.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58322.1 - 9.7e-24 83.8 0.7 1.8e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMD58322.1 - 0.0067 16.1 3.8 0.0075 16.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMD58322.1 - 0.018 14.4 0.3 0.018 14.4 0.2 2.1 2 1 0 2 2 2 0 RIO1 family DUF4430 PF14478.1 EMD58322.1 - 0.041 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) eIF-3c_N PF05470.7 EMD58323.1 - 1.4e-171 571.6 28.8 1.2e-138 462.8 3.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EMD58323.1 - 2e-13 50.5 0.0 2e-13 50.5 0.0 2.8 4 0 0 4 4 4 1 PCI domain DDHD PF02862.12 EMD58323.1 - 10 5.8 11.0 24 4.6 0.1 2.5 2 0 0 2 2 2 0 DDHD domain Per1 PF04080.8 EMD58324.1 - 4.3e-107 357.5 6.3 5.9e-107 357.0 4.3 1.2 1 0 0 1 1 1 1 Per1-like Med7 PF05983.6 EMD58325.1 - 8.7 6.1 7.7 16 5.2 5.4 1.4 1 0 0 1 1 1 0 MED7 protein Nop14 PF04147.7 EMD58326.1 - 0.015 13.2 10.0 0.91 7.3 0.0 2.0 2 0 0 2 2 2 0 Nop14-like family Hydantoinase_B PF02538.9 EMD58327.1 - 4.3e-11 41.7 0.0 7.2e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Glyco_tranf_2_3 PF13641.1 EMD58329.1 - 6.2e-35 121.0 0.0 1.1e-34 120.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD58329.1 - 6e-19 68.5 3.5 6e-19 68.5 2.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMD58329.1 - 1.1e-14 54.1 0.0 1.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD58329.1 - 4.5e-13 49.2 0.0 6.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 EMD58329.1 - 3.1e-05 22.4 0.2 0.013 13.8 0.0 2.5 1 1 2 3 3 3 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EMD58329.1 - 0.0048 16.0 0.0 0.0067 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Borrelia_orfX PF04160.7 EMD58331.1 - 0.15 11.8 1.5 0.15 11.8 1.0 1.0 1 0 0 1 1 1 0 Orf-X protein Actin PF00022.14 EMD58332.1 - 4.1e-92 308.6 0.0 4.9e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Actin Ribosomal_L50 PF10501.4 EMD58333.1 - 4.4e-15 55.6 0.2 1.9e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal subunit 39S MliC PF09864.4 EMD58333.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Transp_cyt_pur PF02133.10 EMD58334.1 - 9.5e-20 70.5 41.8 1.9e-19 69.5 29.0 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sec63 PF02889.11 EMD58336.1 - 7.3e-146 485.3 0.0 7.9e-95 317.6 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMD58336.1 - 1.6e-54 183.9 0.1 1.3e-28 99.6 0.2 4.0 6 0 0 6 6 6 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD58336.1 - 4.4e-16 58.5 0.0 6.1e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMD58336.1 - 1.1e-15 57.8 0.0 8.9e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMD58336.1 - 3.8e-07 30.3 0.1 0.058 13.5 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMD58336.1 - 7.6e-06 25.6 0.1 0.0041 16.7 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMD58336.1 - 9.4e-06 25.2 0.1 0.015 15.0 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 EMD58336.1 - 8.3e-05 21.5 0.1 0.32 9.7 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 EMD58336.1 - 0.022 14.1 0.4 15 4.9 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.11 EMD58336.1 - 0.034 13.3 0.0 2.3 7.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EMD58336.1 - 0.037 13.4 0.0 6.2 6.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMD58336.1 - 0.067 12.6 0.0 11 5.2 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain Synaptobrevin PF00957.16 EMD58337.1 - 3e-13 49.1 0.3 6.3e-13 48.1 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMD58337.1 - 1.6e-10 40.3 0.0 2.9e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 EMD58337.1 - 0.061 13.1 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 MFS_1 PF07690.11 EMD58340.1 - 6.7e-21 74.3 74.6 5.6e-19 68.0 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Polyketide_cyc2 PF10604.4 EMD58341.1 - 6.5e-09 36.0 0.0 7.5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Hemopexin PF00045.14 EMD58341.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Hemopexin Zn_clus PF00172.13 EMD58342.1 - 1.7e-07 31.0 12.3 3e-07 30.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD58342.1 - 8.4e-06 24.6 1.8 2.1e-05 23.2 1.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain EAP30 PF04157.11 EMD58342.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family GldM_N PF12081.3 EMD58342.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain VHP PF02209.14 EMD58342.1 - 0.67 9.6 0.0 0.67 9.6 0.0 2.3 3 0 0 3 3 3 0 Villin headpiece domain IU_nuc_hydro PF01156.14 EMD58344.1 - 5.3e-26 91.5 0.0 6.2e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CFEM PF05730.6 EMD58346.1 - 3.8e-10 39.4 11.8 6.4e-10 38.7 8.2 1.4 1 0 0 1 1 1 1 CFEM domain Methyltransf_12 PF08242.7 EMD58347.1 - 3.6e-05 24.1 0.2 0.00048 20.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CD45 PF12567.3 EMD58347.1 - 0.12 12.1 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Leukocyte receptor CD45 Peptidase_S28 PF05577.7 EMD58349.1 - 8.5e-55 186.0 0.8 8.2e-54 182.8 0.7 2.2 2 1 0 2 2 2 1 Serine carboxypeptidase S28 Caps_synth PF05704.7 EMD58350.1 - 2.6e-11 43.1 0.0 4.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMD58350.1 - 4.8e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMD58350.1 - 0.046 12.2 0.0 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain COesterase PF00135.23 EMD58353.1 - 2e-26 92.7 2.6 1.2e-20 73.7 1.6 3.3 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD58353.1 - 0.0058 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SnoaL_3 PF13474.1 EMD58353.1 - 0.025 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Glyco_hydro_43 PF04616.9 EMD58354.1 - 6.1e-55 186.3 5.9 7.6e-55 186.0 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EMD58354.1 - 1.5e-38 131.7 3.7 3.5e-38 130.5 2.6 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EMD58354.1 - 0.006 15.9 2.9 0.01 15.2 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Kelch_3 PF13415.1 EMD58354.1 - 0.32 11.2 5.3 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain DivIC PF04977.10 EMD58355.1 - 0.00091 18.6 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 EMD58355.1 - 0.0031 17.7 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF904) TSC22 PF01166.13 EMD58355.1 - 0.0069 16.3 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family HALZ PF02183.13 EMD58355.1 - 0.0097 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EMD58355.1 - 0.024 14.3 0.3 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Herpes_BLRF2 PF05812.7 EMD58355.1 - 0.032 14.0 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein FlxA PF14282.1 EMD58355.1 - 0.088 12.7 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 FlxA-like protein NYD-SP28_assoc PF14775.1 EMD58355.1 - 0.1 12.3 0.4 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF972 PF06156.8 EMD58355.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC92 PF14916.1 EMD58355.1 - 0.13 11.8 0.1 0.41 10.2 0.1 1.8 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Amidohydro_1 PF01979.15 EMD58357.1 - 1.6e-17 64.2 0.0 3.7e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMD58357.1 - 5e-13 48.6 0.0 9.4e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD58357.1 - 1.8e-08 34.0 0.2 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMD58357.1 - 3.2e-07 30.6 0.0 0.0009 19.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Zn_clus PF00172.13 EMD58358.1 - 4.3e-08 32.9 13.7 1e-07 31.7 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD58358.1 - 1.5e-07 30.6 1.4 2.6e-07 29.7 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCHC PF00098.18 EMD58359.1 - 0.0063 16.3 2.9 0.0093 15.8 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EMD58359.1 - 0.26 10.7 3.2 0.47 9.9 2.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 EMD58359.1 - 0.3 11.0 2.6 0.43 10.4 1.8 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G bZIP_1 PF00170.16 EMD58359.1 - 7.6 6.5 8.5 18 5.3 5.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor GMC_oxred_N PF00732.14 EMD58360.1 - 8.6e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD58360.1 - 2e-26 93.0 0.0 3.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD58360.1 - 4.7e-05 22.4 0.0 8.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD58360.1 - 0.016 15.1 0.1 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD58360.1 - 0.017 15.1 0.5 0.11 12.5 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD58360.1 - 0.038 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMD58360.1 - 0.038 13.8 0.1 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD58360.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 EMD58360.1 - 0.059 12.2 0.0 0.099 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EMD58360.1 - 0.092 12.8 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase YwhD PF08741.5 EMD58360.1 - 0.15 11.4 0.3 0.33 10.3 0.2 1.5 1 0 0 1 1 1 0 YwhD family Thi4 PF01946.12 EMD58360.1 - 0.18 10.8 0.1 0.38 9.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family CBM_14 PF01607.19 EMD58362.1 - 0.5 10.3 4.6 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain PhyH PF05721.8 EMD58363.1 - 1.6e-07 31.5 0.2 3.8e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EMD58363.1 - 0.00017 20.1 0.1 0.38 9.1 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.13 EMD58364.1 - 2.2e-39 135.5 0.0 4.6e-38 131.2 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMD58364.1 - 5.4e-27 95.0 0.0 7.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMD58364.1 - 4.6e-08 33.2 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD58364.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EMD58365.1 - 1.2e-16 60.3 17.9 1.2e-16 60.3 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD58365.1 - 2.2e-08 33.1 7.5 2.2e-08 33.1 5.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMD58365.1 - 3.8e-05 22.0 0.9 6.2e-05 21.3 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PhyH PF05721.8 EMD58366.1 - 1.7e-12 47.8 0.1 6.8e-12 45.8 0.0 2.1 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EMD58366.1 - 5.4e-06 25.1 0.2 0.62 8.4 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EMD58366.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.13 EMD58367.1 - 2.5e-05 24.0 9.0 3.3e-05 23.6 6.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BmKX PF09132.5 EMD58369.1 - 0.08 12.8 0.1 0.08 12.8 0.1 2.3 3 0 0 3 3 3 0 BmKX GMC_oxred_N PF00732.14 EMD58370.1 - 4e-60 203.4 0.0 5.2e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD58370.1 - 3.1e-37 128.0 0.0 6e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD58370.1 - 8.5e-07 28.1 1.1 1.3e-05 24.2 0.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD58370.1 - 2.3e-06 26.7 0.2 0.0063 15.4 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD58370.1 - 1.5e-05 24.9 0.1 3.5e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD58370.1 - 3.6e-05 22.9 0.1 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMD58370.1 - 0.0013 18.6 0.2 0.013 15.3 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD58370.1 - 0.0016 17.4 0.1 0.003 16.5 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD58370.1 - 0.0018 18.3 0.3 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD58370.1 - 0.0029 16.1 1.1 0.013 14.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EMD58370.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EMD58370.1 - 0.085 12.8 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EMD58370.1 - 0.12 12.8 0.6 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 EMD58371.1 - 6.3e-24 84.0 0.5 1.2e-23 83.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain DUF2435 PF10363.4 EMD58373.1 - 4.1e-12 45.8 0.1 3.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EMD58373.1 - 2.1e-07 30.2 0.9 5.7e-07 28.8 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) LSM PF01423.17 EMD58374.1 - 3.5e-18 64.9 0.4 4.1e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain PPR_2 PF13041.1 EMD58375.1 - 0.00093 19.1 0.0 2.3 8.2 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EMD58375.1 - 0.091 13.0 0.0 17 5.9 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 EMD58375.1 - 0.18 11.8 0.0 6.2 7.0 0.0 3.3 3 0 0 3 3 3 0 PPR repeat Polysacc_deac_1 PF01522.16 EMD58377.1 - 8.8e-30 102.8 0.0 1.4e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMD58377.1 - 1.4e-08 34.5 12.0 1.4e-08 34.5 8.3 1.8 2 0 0 2 2 2 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 EMD58377.1 - 0.017 14.0 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_hydro_16 PF00722.16 EMD58378.1 - 1e-08 34.6 1.1 1.5e-08 34.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Metallophos PF00149.23 EMD58379.1 - 1.1e-38 132.7 0.0 2.3e-33 115.2 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Smg4_UPF3 PF03467.10 EMD58380.1 - 8.6e-20 71.4 0.4 6.3e-19 68.6 0.0 2.7 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 EMD58380.1 - 1.4e-05 25.0 0.0 7.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD58380.1 - 7.8e-05 22.2 0.0 0.00034 20.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD58380.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) peroxidase PF00141.18 EMD58381.1 - 6.4e-24 84.7 0.1 9.1e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EMD58381.1 - 4.5e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) WD40 PF00400.27 EMD58382.1 - 0.15 11.9 2.0 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat MT-A70 PF05063.9 EMD58385.1 - 3.1e-30 105.0 0.0 4.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EMD58385.1 - 0.1 12.6 0.2 0.37 10.8 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EMD58385.1 - 0.15 11.4 0.1 0.51 9.7 0.0 1.9 2 1 1 3 3 3 0 Conserved hypothetical protein 95 Mito_carr PF00153.22 EMD58386.1 - 1.5e-60 200.9 0.8 4.1e-21 74.4 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EMD58387.1 - 7.6e-73 238.0 12.9 5.8e-14 51.3 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 EMD58387.1 - 6.9e-10 38.8 0.0 2.2e-09 37.1 0.0 1.8 2 0 0 2 2 1 1 NACHT domain Nup160 PF11715.3 EMD58387.1 - 1.4e-09 36.6 14.6 0.05 11.7 1.9 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 B_lectin PF01453.19 EMD58387.1 - 2.7e-08 33.6 6.6 0.0025 17.6 0.4 3.4 1 1 2 3 3 3 3 D-mannose binding lectin AAA_16 PF13191.1 EMD58387.1 - 5.4e-08 33.0 0.4 2.4e-06 27.6 0.4 3.0 2 1 0 2 2 2 1 AAA ATPase domain eIF2A PF08662.6 EMD58387.1 - 5.5e-08 32.7 0.0 0.013 15.2 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EMD58387.1 - 2.5e-06 26.6 0.1 7.6 5.9 0.0 5.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Robl_LC7 PF03259.12 EMD58387.1 - 2e-05 24.0 3.5 26 4.4 0.0 5.7 3 2 2 5 5 5 0 Roadblock/LC7 domain IKI3 PF04762.7 EMD58387.1 - 0.00054 17.9 0.8 0.41 8.4 0.1 2.6 1 1 1 2 2 2 2 IKI3 family KAP_NTPase PF07693.9 EMD58387.1 - 0.0013 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 EMD58387.1 - 0.0025 18.0 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD58387.1 - 0.0032 17.5 0.0 0.015 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Stimulus_sens_1 PF13756.1 EMD58387.1 - 0.0037 17.6 1.6 20 5.5 0.0 4.8 2 1 2 5 5 4 0 Stimulus-sensing domain APS_kinase PF01583.15 EMD58387.1 - 0.0039 16.8 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EMD58387.1 - 0.0049 17.6 1.2 0.054 14.3 0.1 2.9 2 2 0 2 2 2 1 AAA domain Coatomer_WDAD PF04053.9 EMD58387.1 - 0.013 14.2 0.1 7.5 5.2 0.0 3.6 1 1 1 3 3 3 0 Coatomer WD associated region AAA_19 PF13245.1 EMD58387.1 - 0.021 14.5 0.0 0.12 12.1 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EMD58387.1 - 0.03 13.1 0.1 0.091 11.5 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EMD58387.1 - 0.045 13.6 0.1 0.73 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Bd3614-deam PF14439.1 EMD58387.1 - 0.06 13.2 3.4 4.7 7.0 0.0 4.3 5 0 0 5 5 5 0 Bd3614-like deaminase AAA_5 PF07728.9 EMD58387.1 - 0.14 11.8 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMD58387.1 - 0.17 12.1 0.1 0.86 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF4333 PF14230.1 EMD58387.1 - 0.24 11.4 3.2 47 4.0 0.0 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF4333) TMF_DNA_bd PF12329.3 EMD58388.1 - 6.6e-23 80.3 15.7 6.6e-23 80.3 10.9 4.7 3 1 1 4 4 4 1 TATA element modulatory factor 1 DNA binding ApoO PF09769.4 EMD58388.1 - 0.34 10.6 5.9 1.3 8.7 1.9 2.9 2 1 0 2 2 2 0 Apolipoprotein O Reo_sigmaC PF04582.7 EMD58388.1 - 0.65 9.1 9.4 0.46 9.6 4.2 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein LOH1CR12 PF10158.4 EMD58388.1 - 0.94 9.2 11.1 0.77 9.5 4.3 2.8 2 1 1 3 3 3 0 Tumour suppressor protein Fib_alpha PF08702.5 EMD58388.1 - 0.98 9.5 26.0 0.21 11.7 7.9 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 EMD58388.1 - 1.8 5.8 43.1 2.3 5.4 29.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CN_hydrolase PF00795.17 EMD58390.1 - 6.7e-25 87.5 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pyridox_oxidase PF01243.15 EMD58391.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF866 PF05907.8 EMD58392.1 - 1.1e-46 158.2 0.1 1.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) T4_baseplate PF12322.3 EMD58392.1 - 0.033 13.4 0.6 0.45 9.7 0.0 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Terminase_GpA PF05876.7 EMD58392.1 - 0.13 10.5 0.9 0.17 10.2 0.6 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF3716 PF12511.3 EMD58392.1 - 0.17 11.5 2.7 0.33 10.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cas_CXXC_CXXC PF09706.5 EMD58392.1 - 0.39 10.9 2.8 3.2 7.9 2.2 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF4379 PF14311.1 EMD58392.1 - 0.47 10.2 4.5 0.19 11.5 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4379) zinc_ribbon_4 PF13717.1 EMD58392.1 - 0.82 9.4 3.6 3.9 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EMD58392.1 - 1.7 8.5 4.7 6.1 6.7 3.3 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TPR_11 PF13414.1 EMD58393.1 - 1.4e-09 37.4 2.1 8.8e-07 28.4 0.0 2.6 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 EMD58393.1 - 1.6e-09 38.2 0.0 1.2e-08 35.4 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 EMD58393.1 - 2.7e-05 23.7 4.9 0.0017 18.0 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD58393.1 - 0.00018 21.7 1.0 0.0015 18.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD58393.1 - 0.0042 16.9 3.0 0.016 15.1 0.2 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EMD58393.1 - 0.035 14.2 1.0 0.1 12.7 0.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1832 PF08870.6 EMD58393.1 - 0.063 12.9 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) HSDR_N_2 PF13588.1 EMD58394.1 - 0.00033 20.4 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) T2SG PF08334.6 EMD58395.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G PhaP_Bmeg PF09602.5 EMD58395.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HET PF06985.6 EMD58396.1 - 2.1e-16 60.3 0.2 2.2e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-CCHC PF00098.18 EMD58397.1 - 0.016 15.1 2.8 0.024 14.5 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle SF-assemblin PF06705.6 EMD58397.1 - 0.026 13.6 0.8 0.03 13.4 0.6 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin zf-MYND PF01753.13 EMD58397.1 - 0.07 13.0 0.7 0.11 12.3 0.5 1.3 1 0 0 1 1 1 0 MYND finger Peptidase_M19 PF01244.16 EMD58398.1 - 3.1e-99 331.9 0.0 3.7e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.17 EMD58399.1 - 1.5e-34 119.3 0.1 2e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 EMD58400.1 - 1.5e-20 73.0 4.3 3.7e-20 71.8 3.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 EMD58402.1 - 7.2e-35 120.3 0.0 7.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C PF00043.20 EMD58403.1 - 5e-05 23.2 0.0 9.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD58403.1 - 0.00032 20.6 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD58403.1 - 0.00098 18.9 0.1 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD58403.1 - 0.00099 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EMD58404.1 - 2.9e-12 45.9 40.5 8.7e-12 44.4 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EMD58405.1 - 1.7e-79 267.1 0.0 4.6e-79 265.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EMD58405.1 - 8.9e-55 185.6 0.0 2.1e-28 99.0 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EMD58405.1 - 5.4e-08 32.9 0.2 1.4e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.10 EMD58405.1 - 0.00027 19.5 0.0 0.24 9.8 0.0 2.8 3 0 0 3 3 3 2 Transferase family HxxPF_rpt PF13745.1 EMD58405.1 - 0.0011 19.2 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EMD58405.1 - 0.0054 17.6 0.3 0.015 16.2 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EMD58406.1 - 2.3e-36 125.1 0.0 2.6e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.16 EMD58407.1 - 1e-42 146.4 0.0 1.3e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMD58407.1 - 0.00013 21.2 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AIG2_2 PF13772.1 EMD58408.1 - 8.9e-06 25.7 0.0 2.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family Pyr_redox_2 PF07992.9 EMD58409.1 - 3.6e-22 79.2 0.0 4.9e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD58409.1 - 5.5e-07 28.7 0.1 6.6e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMD58409.1 - 1.2e-06 28.4 2.3 0.0026 17.5 0.1 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EMD58409.1 - 1.9e-06 27.0 2.4 0.011 14.6 0.1 2.9 2 1 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 EMD58409.1 - 7e-06 24.7 3.3 0.0021 16.5 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 EMD58409.1 - 1.3e-05 25.3 0.4 0.066 13.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD58409.1 - 6.9e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD58409.1 - 0.00031 19.7 1.8 0.009 14.9 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD58409.1 - 0.0015 17.5 0.5 0.1 11.5 0.3 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD58409.1 - 0.0028 17.6 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD58409.1 - 0.026 13.6 0.1 0.043 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DUF3492 PF11997.3 EMD58409.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) Pyr_redox PF00070.22 EMD58409.1 - 0.04 14.3 1.1 0.45 10.9 0.2 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD58409.1 - 0.043 12.4 0.1 0.083 11.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EMD58409.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 EMD58409.1 - 0.056 12.3 0.2 5 5.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EMD58409.1 - 0.062 12.3 0.1 0.062 12.3 0.1 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase MBOAT_2 PF13813.1 EMD58410.1 - 3.4e-06 27.0 0.0 8.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Acetyltransf_1 PF00583.19 EMD58410.1 - 0.00027 20.8 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD58410.1 - 0.0022 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD58410.1 - 0.051 13.7 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD58410.1 - 0.06 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.9 EMD58411.1 - 2.8e-18 66.5 0.0 3.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD58411.1 - 6.9e-06 25.2 1.0 2.6e-05 23.3 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD58411.1 - 8.1e-05 21.6 0.2 0.00063 18.6 0.0 2.3 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EMD58411.1 - 0.00084 19.3 0.3 0.0024 17.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMD58411.1 - 0.0051 15.9 0.1 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD58411.1 - 0.0068 16.4 0.0 1.3 9.0 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD58411.1 - 0.015 13.8 0.0 0.29 9.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EMD58411.1 - 0.016 14.9 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMD58411.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EMD58411.1 - 0.11 11.3 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A MORN_2 PF07661.8 EMD58412.1 - 0.71 10.0 3.1 0.82 9.8 0.1 2.6 3 0 0 3 3 3 0 MORN repeat variant Zn_clus PF00172.13 EMD58414.1 - 1.4e-09 37.6 9.9 4.9e-09 35.9 6.9 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EMD58415.1 - 1.6e-82 277.1 0.2 2e-82 276.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD58415.1 - 0.00051 20.9 0.5 0.0021 18.9 0.3 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.13 EMD58416.1 - 7.7e-41 139.8 0.0 1.2e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Transp_cyt_pur PF02133.10 EMD58417.1 - 2.2e-94 316.4 35.4 2.6e-94 316.2 24.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltransf_2 PF00891.13 EMD58418.1 - 1.2e-28 99.9 0.0 1.8e-28 99.3 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase DREV PF05219.7 EMD58418.1 - 0.024 13.5 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.2 EMD58418.1 - 0.11 13.1 0.2 0.36 11.4 0.1 1.9 1 1 1 2 2 2 0 Methyltransferase domain p450 PF00067.17 EMD58419.1 - 1.3e-28 99.7 0.0 1.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EMD58420.1 - 2.8e-26 91.9 0.0 3e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD58420.1 - 0.054 13.2 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Ank_2 PF12796.2 EMD58421.1 - 1.9e-49 165.9 38.0 1.1e-16 60.9 1.9 4.8 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) HET PF06985.6 EMD58421.1 - 3.9e-36 124.2 1.1 1.4e-35 122.4 0.8 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 EMD58421.1 - 1.7e-31 106.4 47.0 5.1e-05 22.8 0.3 9.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EMD58421.1 - 2.3e-27 94.8 16.8 3.3e-07 30.6 0.1 6.8 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD58421.1 - 1.1e-19 68.4 22.9 0.069 13.4 0.2 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 EMD58421.1 - 1.5e-13 50.4 24.1 5.6e-05 23.2 0.2 7.0 2 1 6 8 8 8 8 Ankyrin repeats (many copies) DUF3396 PF11876.3 EMD58421.1 - 9.1 5.3 7.6 16 4.5 0.1 3.9 1 1 3 5 5 5 0 Protein of unknown function (DUF3396) MFS_1 PF07690.11 EMD58422.1 - 3.8e-39 134.3 38.9 1.2e-33 116.3 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EMD58423.1 - 7.2e-34 117.0 0.0 1.7e-33 115.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMD58423.1 - 2.6e-16 59.8 13.8 2.6e-16 59.8 9.6 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EMD58423.1 - 1e-08 34.7 0.8 6.9e-07 28.7 0.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD58423.1 - 9e-07 29.1 0.2 0.00079 19.4 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EMD58423.1 - 0.00016 21.0 0.4 0.0005 19.5 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMD58423.1 - 0.00022 21.2 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EMD58423.1 - 0.00048 19.3 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD58423.1 - 0.0012 19.0 0.0 0.0037 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMD58423.1 - 0.0015 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMD58423.1 - 0.0025 17.2 0.8 0.019 14.4 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EMD58423.1 - 0.0033 16.8 0.0 0.0094 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EMD58423.1 - 0.011 16.1 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMD58423.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EMD58423.1 - 0.033 13.7 0.1 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMD58423.1 - 0.034 14.0 0.2 0.24 11.3 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EMD58423.1 - 0.036 13.5 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EMD58423.1 - 0.049 14.4 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMD58423.1 - 0.064 12.9 0.1 0.33 10.6 0.1 2.0 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.1 EMD58423.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMD58423.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 GST_N_2 PF13409.1 EMD58424.1 - 1.3e-09 37.9 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMD58424.1 - 7.8e-09 35.6 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD58424.1 - 1.2e-08 34.8 0.6 2e-08 34.1 0.4 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD58424.1 - 6e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD58424.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EMD58425.1 - 1.3e-42 145.9 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UBA PF00627.26 EMD58427.1 - 1.5e-06 27.8 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain XAP5 PF04921.9 EMD58428.1 - 1e-79 267.4 0.5 6e-79 264.9 0.0 1.9 2 0 0 2 2 2 1 XAP5, circadian clock regulator GDPD PF03009.12 EMD58429.1 - 7.2e-73 245.2 0.0 1.2e-72 244.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EMD58429.1 - 2.2e-31 108.0 0.9 3e-14 53.1 0.1 4.5 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD58429.1 - 5.2e-29 100.0 1.8 6e-09 36.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 EMD58429.1 - 3.6e-28 99.1 8.2 6.2e-18 65.5 0.7 3.8 2 1 1 3 3 3 2 SPX domain Ank PF00023.25 EMD58429.1 - 8.3e-24 82.1 6.9 9.2e-06 25.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EMD58429.1 - 9.8e-23 79.6 3.2 2.8e-08 33.7 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD58429.1 - 2.4e-14 52.0 6.7 0.01 15.9 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat UQ_con PF00179.21 EMD58430.1 - 8.6e-32 109.4 0.0 1.5e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD58430.1 - 0.034 13.8 0.0 0.086 12.5 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Nup160 PF11715.3 EMD58431.1 - 3.6e-118 395.0 1.0 4.8e-118 394.6 0.7 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EMD58431.1 - 0.0028 17.4 0.0 0.0087 15.9 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat Aldo_ket_red PF00248.16 EMD58432.1 - 7.2e-55 185.7 0.0 8.5e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.4 EMD58433.1 - 1.2e-25 89.5 13.1 1.2e-25 89.5 9.1 2.4 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4551 PF15087.1 EMD58433.1 - 4.8 5.4 10.2 5.9 5.1 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MFS_1 PF07690.11 EMD58434.1 - 6.3e-29 100.7 48.0 5.5e-17 61.5 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EMD58435.1 - 1.8e-20 72.8 0.9 2.9e-20 72.1 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain SLAC1 PF03595.12 EMD58436.1 - 1.6e-63 214.3 47.3 1.8e-63 214.2 32.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PalH PF08733.5 EMD58436.1 - 0.99 8.1 11.0 0.024 13.4 0.3 2.2 2 0 0 2 2 2 0 PalH/RIM21 MIP PF00230.15 EMD58437.1 - 9.9e-35 120.0 7.7 1.4e-34 119.5 5.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein Vps26 PF03643.10 EMD58438.1 - 3e-128 426.3 0.5 3.5e-128 426.1 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EMD58438.1 - 0.00023 20.9 0.2 0.59 9.9 0.0 3.3 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Atrophin-1 PF03154.10 EMD58439.1 - 0.018 13.2 2.8 0.02 13.0 2.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF2040 PF09745.4 EMD58439.1 - 0.11 12.3 1.0 0.13 12.0 0.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) SKI PF01202.17 EMD58440.1 - 1.2e-13 51.2 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EMD58440.1 - 2.7e-12 47.5 0.0 3.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD58440.1 - 3.6e-10 40.2 0.0 5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD58440.1 - 4.3e-10 39.6 0.0 6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMD58440.1 - 1.3e-06 27.4 0.0 1.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMD58440.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EMD58440.1 - 9.2e-05 22.4 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.1 EMD58440.1 - 0.00019 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD58440.1 - 0.00042 20.0 0.1 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EMD58440.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD58440.1 - 0.0011 19.0 0.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EMD58440.1 - 0.0025 18.1 0.0 0.0036 17.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.16 EMD58440.1 - 0.0028 16.8 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMD58440.1 - 0.0049 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EMD58440.1 - 0.006 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMD58440.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EMD58440.1 - 0.0071 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase tRNA_lig_kinase PF08303.6 EMD58440.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain CoaE PF01121.15 EMD58440.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Zeta_toxin PF06414.7 EMD58440.1 - 0.014 14.5 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EMD58440.1 - 0.028 13.3 0.5 0.096 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EMD58440.1 - 0.029 14.1 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EMD58440.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EMD58440.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 EMD58440.1 - 0.038 13.1 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 EMD58440.1 - 0.048 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Viral_helicase1 PF01443.13 EMD58440.1 - 0.053 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EMD58440.1 - 0.063 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein VirE PF05272.6 EMD58440.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E PRK PF00485.13 EMD58440.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EMD58440.1 - 0.072 12.0 0.0 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EMD58440.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EMD58440.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMD58440.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Glyoxalase_2 PF12681.2 EMD58440.1 - 0.13 12.8 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain gpUL132 PF11359.3 EMD58441.1 - 0.0019 17.5 0.9 0.002 17.5 0.6 1.0 1 0 0 1 1 1 1 Glycoprotein UL132 DUF1180 PF06679.7 EMD58441.1 - 0.013 15.3 0.7 0.017 15.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.1 EMD58441.1 - 0.014 15.0 0.3 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.7 EMD58441.1 - 0.014 14.8 0.4 0.015 14.6 0.3 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor YebO PF13974.1 EMD58441.1 - 0.16 11.8 1.1 0.25 11.1 0.8 1.3 1 0 0 1 1 1 0 YebO-like protein EphA2_TM PF14575.1 EMD58441.1 - 0.27 11.6 1.8 0.38 11.1 1.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.6 EMD58441.1 - 0.73 9.6 8.4 1.2 8.9 5.8 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PsbJ PF01788.12 EMD58441.1 - 6.4 6.3 6.4 17 5.0 4.4 1.8 1 1 0 1 1 1 0 PsbJ Sulfate_transp PF00916.15 EMD58442.1 - 1.2e-43 149.0 5.0 2.5e-43 148.0 3.5 1.5 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EMD58442.1 - 2.1e-16 59.5 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EMD58442.1 - 1.3e-07 31.0 0.1 2.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain DAGK_cat PF00781.19 EMD58443.1 - 8.1e-24 83.5 0.1 1.3e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 EMD58444.1 - 1.1e-89 301.2 1.6 2.3e-89 300.0 1.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EMD58444.1 - 6.4e-63 210.2 0.0 1.7e-62 208.8 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EMD58444.1 - 5.5e-61 204.3 2.1 1.1e-60 203.3 1.5 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EMD58444.1 - 3.1e-10 40.1 2.9 2.6e-06 27.5 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EMD58444.1 - 0.00016 21.5 6.4 0.019 14.7 0.0 4.6 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMD58444.1 - 0.00028 20.7 1.3 0.1 12.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EMD58444.1 - 0.00053 20.3 1.9 0.092 13.2 0.0 4.6 4 1 1 5 5 5 2 HEAT-like repeat DUF3730 PF12530.3 EMD58444.1 - 0.004 17.1 0.5 3.3 7.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3730) AP4E_app_platf PF14807.1 EMD58444.1 - 0.029 14.5 0.1 0.1 12.7 0.1 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Mago_nashi PF02792.9 EMD58445.1 - 4.9e-75 250.0 0.2 5.7e-75 249.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EMD58446.1 - 1.8e-69 232.7 0.6 2.3e-69 232.4 0.4 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF4106 PF13388.1 EMD58446.1 - 2.6 6.8 10.3 3.8 6.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Methyltransf_4 PF02390.12 EMD58447.1 - 1.7e-54 183.8 0.0 2.3e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EMD58447.1 - 1.9e-05 25.0 0.0 5.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD58447.1 - 2.6e-05 23.8 0.0 5.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD58447.1 - 6.5e-05 23.2 0.0 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD58447.1 - 7.6e-05 23.2 0.0 0.00013 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD58447.1 - 0.00027 20.9 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD58447.1 - 0.0003 20.2 0.0 0.00093 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EMD58447.1 - 0.0011 18.0 0.0 0.0049 15.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 EMD58447.1 - 0.0017 18.8 0.1 0.021 15.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMD58447.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EMD58447.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Oxidored_FMN PF00724.15 EMD58448.1 - 4.7e-68 229.6 0.0 4e-65 220.0 0.0 2.6 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF1905 PF08922.6 EMD58448.1 - 0.047 13.2 0.4 0.3 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) CsbD PF05532.7 EMD58449.1 - 4e-06 26.3 7.1 0.00032 20.3 0.1 2.2 2 0 0 2 2 2 2 CsbD-like NrfD_2 PF14589.1 EMD58450.1 - 0.048 13.3 0.5 0.071 12.7 0.4 1.2 1 0 0 1 1 1 0 Polysulfide reductase zf-CCHC_3 PF13917.1 EMD58452.1 - 0.057 13.1 0.3 0.099 12.3 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EMD58452.1 - 0.089 12.7 0.4 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle CtIP_N PF10482.4 EMD58452.1 - 0.12 12.1 3.2 0.5 10.1 0.1 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain WD40 PF00400.27 EMD58455.1 - 1.6e-29 100.6 6.4 2.1e-07 30.5 0.5 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat adh_short PF00106.20 EMD58455.1 - 1.3e-18 67.4 2.7 7.2e-17 61.7 0.2 2.6 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD58455.1 - 6e-13 49.1 1.4 1.3e-11 44.7 1.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD58455.1 - 5.3e-10 39.2 0.3 1.5e-09 37.8 0.1 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMD58455.1 - 0.0037 16.2 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Cytochrom_D1 PF02239.11 EMD58455.1 - 0.0058 14.9 0.1 0.18 10.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Shikimate_DH PF01488.15 EMD58455.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyoxal_oxid_N PF07250.6 EMD58455.1 - 0.098 11.7 0.0 15 4.5 0.0 2.5 3 0 0 3 3 3 0 Glyoxal oxidase N-terminus RNA_lig_T4_1 PF09511.5 EMD58456.1 - 7.1e-76 254.5 0.0 1.7e-75 253.2 0.0 1.7 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EMD58456.1 - 4.1e-74 249.0 0.0 5.9e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EMD58456.1 - 3.4e-51 173.4 0.2 1.4e-50 171.4 0.0 2.1 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EMD58456.1 - 0.0066 17.2 1.0 0.23 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain HgmA PF04209.8 EMD58457.1 - 1.9e-151 504.2 0.0 2.1e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Got1 PF04178.7 EMD58458.1 - 5.4e-32 110.3 16.4 7e-32 110.0 11.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Claudin_2 PF13903.1 EMD58458.1 - 3 7.5 14.4 0.94 9.1 3.0 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction HLH PF00010.21 EMD58460.1 - 2.6e-12 46.2 0.0 7.5e-12 44.7 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3646 PF12362.3 EMD58460.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal NPR3 PF03666.8 EMD58463.1 - 4.2e-147 490.3 0.0 6.8e-147 489.6 0.0 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CHCH PF06747.8 EMD58463.1 - 0.00017 21.3 0.6 0.00029 20.6 0.4 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EMD58463.1 - 0.1 12.6 0.3 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 p450 PF00067.17 EMD58464.1 - 3e-83 279.8 0.0 4e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMD58464.1 - 3.7e-38 131.1 0.0 7.4e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD58464.1 - 1.3e-27 96.5 0.0 3e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMD58464.1 - 8.1e-15 55.3 0.0 4.2e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EMD58464.1 - 8.9e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 EMD58464.1 - 0.00041 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain RDD PF06271.7 EMD58465.1 - 3.1 7.7 15.6 38 4.1 0.0 3.8 3 1 0 3 3 3 0 RDD family ECH PF00378.15 EMD58466.1 - 9.9e-11 41.2 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF898 PF05987.8 EMD58467.1 - 0.58 8.9 18.5 0.025 13.4 6.9 1.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) HET PF06985.6 EMD58468.1 - 1.2e-31 109.7 0.1 2.5e-31 108.6 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2263 PF10021.4 EMD58469.1 - 7.1e-16 58.5 0.0 2.8e-15 56.6 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EMD58469.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Macro domain Pec_lyase_C PF00544.14 EMD58470.1 - 2e-20 73.1 4.3 3.5e-20 72.3 3.0 1.4 1 0 0 1 1 1 1 Pectate lyase Peptidase_M49 PF03571.10 EMD58471.1 - 2.4e-234 778.5 0.0 2.9e-234 778.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Oxidored_FMN PF00724.15 EMD58472.1 - 2.7e-90 302.8 0.0 3.1e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EMD58473.1 - 1.1e-44 152.5 56.5 2.3e-44 151.5 37.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD58473.1 - 4.1e-15 55.3 13.1 4.1e-15 55.3 9.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMD58473.1 - 5.2e-15 54.6 15.6 9.8e-15 53.7 10.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Polysacc_deac_1 PF01522.16 EMD58474.1 - 8.6e-16 57.6 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 EMD58475.1 - 1.4e-28 99.4 0.6 2.8e-28 98.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD58476.1 - 5.2e-09 35.8 11.7 7e-09 35.4 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer4_4 PF12800.2 EMD58476.1 - 6.8 7.3 7.9 11 6.7 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Transp_cyt_pur PF02133.10 EMD58477.1 - 2.9e-95 319.4 44.3 3.4e-95 319.2 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3040 PF11239.3 EMD58477.1 - 1.7 8.7 0.0 1.7 8.7 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) Amidase PF01425.16 EMD58478.1 - 6.3e-72 242.8 0.1 7.6e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 Amidase Nop14 PF04147.7 EMD58479.1 - 6.4 4.5 10.9 7.4 4.3 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.17 EMD58480.1 - 5.3e-55 186.7 0.0 6.6e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CWC25 PF12542.3 EMD58482.1 - 1.1e-20 73.8 0.1 1.1e-20 73.8 0.0 3.8 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EMD58482.1 - 4.4e-13 48.9 10.2 4.4e-13 48.9 7.1 4.5 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR MIP-T3 PF10243.4 EMD58482.1 - 3.4 6.0 54.7 0.036 12.5 32.0 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 EMD58483.1 - 1.7e-05 24.3 0.0 1.2 8.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD58483.1 - 0.00026 20.8 0.0 0.0062 16.5 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.5 EMD58483.1 - 0.0098 16.1 10.3 0.0098 16.1 7.2 2.5 2 1 1 3 3 3 1 Centromere protein B dimerisation domain RRM_5 PF13893.1 EMD58483.1 - 0.046 13.5 0.0 0.49 10.2 0.0 2.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.3 EMD58483.1 - 2.2 6.7 10.3 0.23 10.0 2.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SYF2 PF08231.7 EMD58484.1 - 4.7e-44 150.1 14.4 1e-43 149.1 10.0 1.6 1 0 0 1 1 1 1 SYF2 splicing factor DUF4286 PF14114.1 EMD58484.1 - 0.51 10.6 4.8 13 6.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) AMP-binding PF00501.23 EMD58485.1 - 7.8e-81 271.5 0.0 1.3e-80 270.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMD58485.1 - 4.8e-63 212.4 0.0 1.8e-62 210.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMD58485.1 - 3.3e-33 114.9 3.9 4.2e-30 104.8 1.4 3.2 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 EMD58485.1 - 2.1e-16 60.0 0.0 2.4e-08 33.6 0.0 3.6 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.5 EMD58485.1 - 2.2e-16 60.0 2.3 2.6e-13 50.0 1.2 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.20 EMD58485.1 - 3.1e-13 49.7 0.0 8.6e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.1 EMD58485.1 - 3.1e-13 50.0 0.1 1.1e-12 48.2 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EMD58485.1 - 1.6e-09 36.8 0.3 4.1e-06 25.7 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EMD58485.1 - 2.5e-07 31.5 0.0 2e-06 28.6 0.0 2.7 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 EMD58485.1 - 3.8e-05 22.7 0.1 0.0058 15.5 0.0 3.1 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMD58485.1 - 0.00011 22.3 1.5 0.0089 16.0 0.4 3.5 3 2 1 4 4 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD58485.1 - 0.00018 20.4 0.8 0.54 9.0 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMD58485.1 - 0.0026 17.5 0.7 0.0092 15.7 0.5 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMD58485.1 - 0.064 12.3 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HNOB PF07700.10 EMD58485.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding HHH_5 PF14520.1 EMD58485.1 - 0.14 12.3 1.2 0.59 10.3 0.8 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain RVT_1 PF00078.22 EMD58486.1 - 0.00011 21.5 0.0 0.00027 20.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AKNA PF12443.3 EMD58486.1 - 0.034 14.1 1.3 0.074 13.0 0.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1206 PF06724.6 EMD58487.1 - 2.5 7.9 6.6 0.26 11.0 0.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF3816 PF12822.2 EMD58487.1 - 8.6 6.2 17.9 3.5 7.4 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Pkinase PF00069.20 EMD58489.1 - 5.2e-37 127.4 0.8 8.9e-37 126.6 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58489.1 - 6.6e-23 81.1 0.7 1.1e-22 80.3 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EMD58489.1 - 3.5e-20 71.5 3.6 6.6e-20 70.6 2.5 1.5 1 0 0 1 1 1 1 Hr1 repeat C1_1 PF00130.17 EMD58489.1 - 6.9e-20 70.5 33.3 1.2e-11 44.1 7.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Uds1 PF15456.1 EMD58489.1 - 0.02 14.8 1.1 0.044 13.7 0.8 1.4 1 0 0 1 1 1 0 Up-regulated During Septation AMP-binding PF00501.23 EMD58490.1 - 1.2e-68 231.4 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD58490.1 - 7e-10 39.7 0.1 2.4e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DNA_pol3_theta PF06440.6 EMD58490.1 - 0.11 12.1 0.1 14 5.3 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase III, theta subunit Kin17_mid PF10357.4 EMD58491.1 - 2.8e-45 153.0 1.3 2.8e-45 153.0 0.9 1.8 1 1 1 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EMD58491.1 - 0.00081 19.5 3.9 0.0018 18.4 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type TFIID_90kDa PF04494.10 EMD58491.1 - 0.0081 16.2 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit zf-C2H2_jaz PF12171.3 EMD58491.1 - 0.0092 16.0 2.2 0.021 14.9 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD58491.1 - 0.12 12.5 0.2 0.12 12.5 0.1 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GvpL_GvpF PF06386.6 EMD58491.1 - 0.46 10.0 7.3 0.68 9.4 5.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Band_7 PF01145.20 EMD58492.1 - 7e-32 110.7 0.4 7e-32 110.7 0.3 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMD58492.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 0 SPFH domain-Band 7 family DegQ PF08181.6 EMD58492.1 - 0.2 11.4 0.6 0.46 10.2 0.4 1.6 1 0 0 1 1 1 0 DegQ (SacQ) family Abhydrolase_6 PF12697.2 EMD58493.1 - 7.3e-07 29.2 2.9 1.2e-06 28.5 2.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMD58493.1 - 0.00011 21.8 0.1 0.034 13.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD58493.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD58493.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 EMD58493.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2424 PF10340.4 EMD58493.1 - 0.16 10.5 0.0 0.37 9.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DUF4345 PF14248.1 EMD58494.1 - 0.066 12.6 1.4 4.4 6.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Gp5_C PF06715.7 EMD58494.1 - 2.7 8.1 7.2 5.1 7.2 4.7 1.7 1 1 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) CBF PF03914.12 EMD58495.1 - 2.1e-50 170.3 0.5 6e-50 168.8 0.3 1.8 1 0 0 1 1 1 1 CBF/Mak21 family Glycos_transf_3 PF00591.16 EMD58496.1 - 2.4e-62 210.6 0.0 3.5e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EMD58496.1 - 1.8e-10 40.2 0.0 9e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain zf-C2H2 PF00096.21 EMD58499.1 - 4.1e-07 29.9 8.1 4.1e-05 23.6 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD58499.1 - 2.9e-06 27.1 7.4 0.00066 19.8 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD58499.1 - 8.5e-05 22.6 2.1 8.5e-05 22.6 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD58499.1 - 0.014 15.5 0.8 0.039 14.1 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMD58499.1 - 0.016 15.0 0.5 0.045 13.6 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EMD58499.1 - 2.7 8.3 5.9 0.27 11.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ATP_bind_1 PF03029.12 EMD58500.1 - 6.6e-69 232.0 0.0 6.2e-68 228.8 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EMD58500.1 - 1.8e-05 24.2 0.0 0.0078 15.6 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD58500.1 - 6.3e-05 23.1 0.0 0.00021 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EMD58500.1 - 0.00012 22.5 0.0 0.32 11.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EMD58500.1 - 0.00015 21.0 0.0 0.16 11.1 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD58500.1 - 0.00019 21.3 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EMD58500.1 - 0.00089 18.7 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 EMD58500.1 - 0.00098 18.4 0.0 0.048 12.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B ArgK PF03308.11 EMD58500.1 - 0.001 17.9 0.0 0.063 12.0 0.0 2.3 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 EMD58500.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 EMD58500.1 - 0.0026 17.6 1.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMD58500.1 - 0.0068 17.2 1.3 0.033 15.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD58500.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EMD58500.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain SRPRB PF09439.5 EMD58500.1 - 0.0092 15.2 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMD58500.1 - 0.01 15.2 0.0 2.5 7.4 0.0 2.6 3 0 0 3 3 3 0 Ras family PRK PF00485.13 EMD58500.1 - 0.013 15.1 0.1 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EMD58500.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EMD58500.1 - 0.022 14.1 0.1 0.83 9.0 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EMD58500.1 - 0.029 14.5 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Asn_synthase PF00733.16 EMD58500.1 - 0.032 13.7 0.2 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Asparagine synthase SRP54 PF00448.17 EMD58500.1 - 0.043 13.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.7 EMD58500.1 - 0.049 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EMD58500.1 - 0.057 12.0 1.2 1.5 7.4 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.12 EMD58500.1 - 0.062 13.1 0.8 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EMD58500.1 - 0.077 13.3 1.0 0.26 11.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EMD58500.1 - 0.079 12.4 0.2 2.2 7.7 0.0 2.9 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EMD58500.1 - 0.084 12.0 0.0 0.27 10.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EMD58500.1 - 0.09 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EMD58500.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EMD58500.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 EMD58500.1 - 0.28 10.6 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family CwfJ_C_1 PF04677.10 EMD58501.1 - 3.9e-27 94.3 0.0 3.8e-26 91.1 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EMD58501.1 - 1.2e-21 76.9 0.0 1.2e-21 76.9 0.0 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CorA PF01544.13 EMD58502.1 - 8.5e-09 34.8 3.3 2.1e-08 33.5 0.4 2.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Rad60-SLD_2 PF13881.1 EMD58504.1 - 2.9e-13 49.6 0.1 5.5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD58504.1 - 0.00014 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMD58504.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF92 PF01940.11 EMD58505.1 - 1.4e-60 204.2 9.9 2.1e-60 203.7 6.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 UMP1 PF05348.6 EMD58505.1 - 1.3e-24 86.6 0.0 2.6e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 adh_short PF00106.20 EMD58506.1 - 7.3e-18 65.0 0.0 9.4e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD58506.1 - 3.7e-11 43.0 0.0 4.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD58506.1 - 3e-08 33.7 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMD58506.1 - 0.001 19.0 0.1 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD58506.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMD58506.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 EMD58507.1 - 4.8e-35 120.9 0.0 3e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 RGS PF00615.14 EMD58507.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain HET PF06985.6 EMD58510.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EMD58511.1 - 5.7e-10 38.3 0.1 6.1e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.9 EMD58512.1 - 4e-07 29.8 0.0 4.3e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_4 PF01565.18 EMD58513.1 - 5.8e-21 74.4 5.5 1.1e-20 73.5 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain MMR_HSR1 PF01926.18 EMD58514.1 - 2.3e-05 24.3 0.0 7.5e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMD58514.1 - 0.00033 19.8 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EMD58514.1 - 0.034 13.9 3.3 3.5 7.4 0.0 3.2 2 2 1 3 3 3 0 Dynamin family DUF2663 PF10864.3 EMD58514.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) MMR_HSR1 PF01926.18 EMD58515.1 - 6.1e-16 58.4 0.2 9.3e-08 32.0 0.0 3.6 2 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD58515.1 - 3.9e-08 32.7 0.1 0.00058 19.1 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.11 EMD58515.1 - 8.6e-08 31.5 0.2 0.00027 20.1 0.0 3.6 4 0 0 4 4 3 2 AIG1 family DUF258 PF03193.11 EMD58515.1 - 1.4e-07 30.8 0.6 0.0027 16.9 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMD58515.1 - 1e-06 29.2 0.6 0.011 16.2 0.0 3.6 3 0 0 3 3 3 2 Miro-like protein AAA_22 PF13401.1 EMD58515.1 - 2e-05 24.7 0.6 0.47 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EMD58515.1 - 0.00056 20.2 13.2 0.53 10.5 0.0 4.9 4 0 0 4 4 4 2 ABC transporter AAA_14 PF13173.1 EMD58515.1 - 0.00063 19.6 0.0 0.35 10.7 0.0 3.4 2 0 0 2 2 2 1 AAA domain IIGP PF05049.8 EMD58515.1 - 0.0011 17.8 2.6 0.19 10.5 0.0 3.3 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.13 EMD58515.1 - 0.0012 18.3 0.2 2.1 7.8 0.1 2.9 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EMD58515.1 - 0.0012 17.7 5.5 0.04 12.8 0.1 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein ArgK PF03308.11 EMD58515.1 - 0.002 16.9 0.0 0.46 9.2 0.0 3.0 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 EMD58515.1 - 0.0027 17.2 11.6 2.2 7.6 0.8 3.9 3 1 0 3 3 3 2 AAA-like domain MobB PF03205.9 EMD58515.1 - 0.0051 16.5 1.3 8.1 6.1 0.1 3.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EMD58515.1 - 0.0051 15.9 0.0 1.4 7.9 0.0 3.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMD58515.1 - 0.0052 16.3 7.2 2.5 7.5 0.1 4.8 2 2 2 4 4 4 2 Conserved hypothetical ATP binding protein Arf PF00025.16 EMD58515.1 - 0.0058 15.8 0.0 0.15 11.3 0.0 2.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.1 EMD58515.1 - 0.012 15.1 0.7 0.31 10.6 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMD58515.1 - 0.018 14.8 27.4 0.82 9.4 0.0 7.2 5 3 2 7 7 7 0 Dynamin family SRP54 PF00448.17 EMD58515.1 - 0.021 14.2 2.8 2.5 7.4 0.0 3.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EMD58515.1 - 0.033 15.0 17.0 0.076 13.8 0.0 4.7 4 1 0 4 4 3 0 AAA domain AAA_16 PF13191.1 EMD58515.1 - 0.045 13.7 15.1 0.56 10.1 0.0 4.6 4 1 1 5 5 5 0 AAA ATPase domain Rep_fac_C PF08542.6 EMD58515.1 - 0.073 13.0 0.3 8.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Replication factor C C-terminal domain RNA_helicase PF00910.17 EMD58515.1 - 0.083 13.0 4.6 8.6 6.5 0.0 3.7 3 0 0 3 3 3 0 RNA helicase GTP_EFTU PF00009.22 EMD58515.1 - 0.18 11.1 10.9 2.2 7.6 0.5 4.7 3 3 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMD58515.1 - 0.19 11.6 0.0 0.19 11.6 0.0 4.7 6 0 0 6 6 4 0 AAA domain cobW PF02492.14 EMD58515.1 - 0.2 11.0 3.1 7 6.0 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EMD58515.1 - 0.68 10.2 23.8 2 8.7 0.0 5.5 4 1 0 4 4 3 0 AAA domain EMP24_GP25L PF01105.19 EMD58515.1 - 2.2 7.9 18.5 2.6 7.7 0.3 3.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD GFO_IDH_MocA PF01408.17 EMD58516.1 - 2.2e-19 70.1 0.0 4.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 EMD58517.1 - 8e-28 97.1 37.5 8e-28 97.1 26.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Galactosyl_T PF01762.16 EMD58517.1 - 0.22 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase ATG27 PF09451.5 EMD58518.1 - 2.2e-59 200.9 0.6 5.1e-59 199.6 0.4 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EMD58518.1 - 7e-05 22.6 0.2 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat KAR9 PF08580.5 EMD58520.1 - 1.2 7.3 20.8 1.4 7.1 14.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ADH_zinc_N PF00107.21 EMD58521.1 - 1.4e-11 44.0 0.0 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD58521.1 - 9.9e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMD58521.1 - 0.0011 18.5 0.3 0.0086 15.6 0.2 2.2 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 EMD58521.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EMD58521.1 - 0.004 18.0 0.9 0.026 15.4 0.0 2.6 2 2 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EMD58521.1 - 0.0049 17.1 0.1 0.067 13.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EMD58521.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 EMD58521.1 - 0.021 14.7 0.7 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.14 EMD58521.1 - 0.083 13.4 0.1 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Con-6 PF10346.4 EMD58522.1 - 3.7e-34 115.8 7.1 1.9e-17 62.3 0.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EMD58522.1 - 0.0033 16.9 3.7 0.19 11.1 0.2 2.2 1 1 1 2 2 2 2 SpoIIIAH-like protein Toxin_52 PF15605.1 EMD58522.1 - 0.029 14.2 1.3 0.44 10.4 0.1 2.1 1 1 1 2 2 2 0 Putative toxin 52 DUF756 PF05506.7 EMD58523.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF756) N2227 PF07942.7 EMD58524.1 - 3.4e-86 288.5 0.0 4.6e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EMD58524.1 - 3.8e-06 26.7 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD58524.1 - 0.042 14.3 0.0 0.2 12.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMD58524.1 - 0.056 13.9 0.0 0.24 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMD58524.1 - 0.092 13.3 0.0 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain LSM PF01423.17 EMD58526.1 - 1.1e-17 63.2 0.2 1.4e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EMD58526.1 - 0.019 15.3 7.8 0.036 14.4 5.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 GRP PF07172.6 EMD58526.1 - 5.3 7.5 20.9 8.9 6.8 14.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family Zn_clus PF00172.13 EMD58527.1 - 0.021 14.7 9.0 0.046 13.6 6.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.6 EMD58528.1 - 1.9e-16 59.3 0.5 2.7e-16 58.8 0.3 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMD58528.1 - 0.0065 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Peptidase_C12 PF01088.16 EMD58529.1 - 9.8e-54 181.7 0.0 1.2e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Enolase_N PF03952.11 EMD58529.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Enolase, N-terminal domain p450 PF00067.17 EMD58530.1 - 5.6e-41 140.5 0.0 6.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.4 EMD58531.1 - 5.8e-20 71.4 0.1 7.8e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMD58531.1 - 1.2e-08 34.4 0.4 3e-08 33.1 0.3 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD58531.1 - 0.00023 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD58531.1 - 0.00045 19.8 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMD58531.1 - 0.0062 16.1 0.1 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EMD58531.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COesterase PF00135.23 EMD58531.1 - 0.034 12.8 0.1 0.071 11.8 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family Eno-Rase_NADH_b PF12242.3 EMD58531.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BAAT_C PF08840.6 EMD58531.1 - 0.062 12.9 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 EMD58531.1 - 0.084 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EMD58531.1 - 0.094 12.1 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EMD58531.1 - 0.11 11.9 0.0 0.48 9.8 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PFK PF00365.15 EMD58531.1 - 0.12 11.3 0.7 0.32 9.9 0.4 1.7 2 0 0 2 2 2 0 Phosphofructokinase p450 PF00067.17 EMD58532.1 - 1.9e-44 151.9 0.0 2.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SdpI PF13630.1 EMD58536.1 - 2.1 8.0 6.8 11 5.8 0.9 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family HET PF06985.6 EMD58537.1 - 1.6e-24 86.6 0.8 2e-24 86.3 0.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HeLo PF14479.1 EMD58538.1 - 5.7e-05 22.9 0.4 7.5e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HeLo PF14479.1 EMD58539.1 - 4e-09 36.5 0.1 5.7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET PF06985.6 EMD58540.1 - 1.3e-28 99.8 0.2 2.6e-28 98.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EMD58541.1 - 6.7e-34 117.0 0.1 1.4e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SF-assemblin PF06705.6 EMD58542.1 - 0.01 14.9 1.6 0.011 14.8 1.1 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin PNP_UDP_1 PF01048.15 EMD58543.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.4 1 1 0 1 1 1 0 Phosphorylase superfamily Metal_CEHH PF14455.1 EMD58543.1 - 0.12 11.7 0.0 0.54 9.6 0.0 1.9 2 1 0 2 2 2 0 Predicted metal binding domain FAD_binding_9 PF08021.6 EMD58544.1 - 0.04 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain HET PF06985.6 EMD58544.1 - 0.13 12.4 0.2 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 EMD58545.1 - 5.5e-82 275.1 0.0 7.7e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD58545.1 - 4.2e-44 150.7 0.0 7.8e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD58545.1 - 2.4e-20 72.2 0.0 4.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain HEAT_2 PF13646.1 EMD58546.1 - 1.4e-09 38.0 0.7 0.003 17.8 0.1 2.6 1 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EMD58546.1 - 0.00014 21.6 0.1 0.64 10.2 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EMD58546.1 - 0.0013 19.1 2.5 0.14 12.6 0.0 3.7 3 1 1 4 4 4 1 HEAT-like repeat DNA_alkylation PF08713.6 EMD58546.1 - 0.0013 18.2 0.8 4.8 6.6 0.0 3.4 2 2 1 3 3 3 2 DNA alkylation repair enzyme DUF2435 PF10363.4 EMD58546.1 - 0.0034 17.2 0.4 1.8 8.4 0.1 3.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EMD58546.1 - 0.054 13.3 0.0 7.1 6.4 0.0 3.0 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EMD58546.1 - 0.083 11.1 0.1 5.9 5.0 0.0 2.0 1 1 0 2 2 2 0 Adaptin N terminal region Asp PF00026.18 EMD58549.1 - 1.1e-33 116.9 0.2 1.5e-33 116.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Sugar_tr PF00083.19 EMD58550.1 - 1.1e-83 281.3 23.2 1.3e-83 281.1 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD58550.1 - 1.5e-17 63.3 23.4 1.5e-17 63.3 16.2 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily PP2C PF00481.16 EMD58556.1 - 5.4e-37 127.5 0.1 3.9e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMD58556.1 - 4e-05 23.1 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C HEAT_EZ PF13513.1 EMD58558.1 - 1.4e-14 54.0 13.9 7.4e-07 29.4 0.0 9.2 9 2 1 10 10 10 1 HEAT-like repeat IBN_N PF03810.14 EMD58558.1 - 2.7e-14 52.8 2.6 1.6e-12 47.1 0.4 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EMD58558.1 - 2.9e-14 53.1 11.0 8.4e-06 25.9 0.0 7.2 4 3 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EMD58558.1 - 2.4e-13 48.9 8.0 0.00032 20.5 0.0 8.3 10 0 0 10 10 10 2 HEAT repeat CLASP_N PF12348.3 EMD58558.1 - 1.5e-08 34.2 0.0 0.0036 16.6 0.0 4.5 3 1 2 5 5 5 2 CLASP N terminal RIX1 PF08167.7 EMD58558.1 - 3.7e-05 23.4 0.0 0.017 14.7 0.0 4.3 2 1 1 4 4 4 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.3 EMD58558.1 - 0.0026 17.7 0.1 0.75 9.7 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Arm PF00514.18 EMD58558.1 - 0.047 13.5 9.3 0.62 9.9 0.0 5.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EMD58558.1 - 2.3 8.9 8.0 21 5.9 0.0 5.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Cation_efflux PF01545.16 EMD58559.1 - 9.6e-33 113.4 5.0 1.2e-32 113.1 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4212 PF13937.1 EMD58559.1 - 0.74 9.8 3.7 0.24 11.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Fungal_trans PF04082.13 EMD58560.1 - 1.1e-29 103.0 0.1 2.8e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD58560.1 - 1.3e-07 31.4 7.7 2.6e-07 30.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2 PF00703.16 EMD58561.1 - 2.2e-10 40.9 0.0 6.3e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EMD58561.1 - 4e-09 36.2 0.9 4.2e-08 32.9 0.1 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMD58561.1 - 0.0053 15.6 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Thaumatin PF00314.12 EMD58562.1 - 7.8e-79 264.0 2.5 9.5e-79 263.7 1.7 1.1 1 0 0 1 1 1 1 Thaumatin family Cyt-b5 PF00173.23 EMD58563.1 - 1.1e-19 69.9 0.2 1.5e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EMD58563.1 - 1.2e-08 35.3 22.8 1.7e-08 34.8 15.0 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EMD58563.1 - 0.03 14.3 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 EMD58563.1 - 0.046 13.3 0.9 0.15 11.6 0.3 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.17 EMD58564.1 - 3e-47 158.1 1.2 7.8e-21 73.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD58564.1 - 8.2e-36 121.8 0.4 4.1e-17 61.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD58564.1 - 6.2e-24 83.6 0.0 8.8e-09 35.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EMD58564.1 - 3.3e-15 56.1 0.0 6.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 EMD58564.1 - 0.011 15.4 0.0 0.38 10.5 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EMD58564.1 - 0.75 8.1 22.7 1.2 7.5 15.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TruD PF01142.13 EMD58565.1 - 4.5e-50 170.4 3.2 6.3e-48 163.3 0.1 3.9 4 1 0 4 4 4 3 tRNA pseudouridine synthase D (TruD) DUF3881 PF12997.2 EMD58565.1 - 0.042 12.8 0.8 0.071 12.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) PHD PF00628.24 EMD58567.1 - 7e-09 35.2 4.7 1.1e-08 34.5 3.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMD58567.1 - 0.005 16.1 2.7 0.0079 15.4 1.9 1.3 1 0 0 1 1 1 1 PHD-finger Herpes_gE PF02480.11 EMD58568.1 - 0.0028 16.0 0.2 0.034 12.4 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 EMD58568.1 - 0.0052 16.2 0.3 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EMD58568.1 - 0.02 15.2 0.1 0.069 13.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DEC-1_N PF04625.8 EMD58568.1 - 0.23 10.1 4.3 0.34 9.5 3.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TMEM154 PF15102.1 EMD58568.1 - 0.39 10.4 5.2 0.31 10.7 0.2 2.4 2 1 0 2 2 2 0 TMEM154 protein family ELO PF01151.13 EMD58570.1 - 2.5e-87 292.3 7.2 3.1e-87 292.0 5.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family APC10 PF03256.11 EMD58571.1 - 3.3e-44 150.8 0.0 3.6e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF3287 PF11690.3 EMD58571.1 - 0.12 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) VIT1 PF01988.14 EMD58572.1 - 1.7 8.1 12.4 2.9 7.3 1.8 2.3 2 1 0 2 2 2 0 VIT family MFS_1 PF07690.11 EMD58574.1 - 1e-38 132.9 26.7 1.5e-38 132.4 18.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD58574.1 - 3.9e-11 42.2 19.1 5.4e-11 41.7 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter CN_hydrolase PF00795.17 EMD58576.1 - 1.5e-23 83.1 0.0 2.2e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gene66 PF02053.10 EMD58576.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein FBPase PF00316.15 EMD58577.1 - 1.5e-53 181.7 0.0 1.8e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EMD58577.1 - 0.082 12.1 1.3 0.095 11.9 0.1 1.6 2 0 0 2 2 2 0 Inositol monophosphatase family DUF3947 PF13135.1 EMD58579.1 - 1.6 8.9 7.3 3.4 7.9 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Peptidase_M24 PF00557.19 EMD58580.1 - 1.4e-57 194.6 0.0 2e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMD58580.1 - 1.6e-27 95.5 0.0 3.1e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain F-box PF00646.28 EMD58581.1 - 0.00096 18.7 0.1 0.004 16.7 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD58581.1 - 0.001 18.7 0.3 0.0035 17.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 EMD58581.1 - 4.1 6.8 16.8 6.9 6.1 11.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EMD58581.1 - 5 6.2 13.2 6.8 5.8 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein PARP PF00644.15 EMD58582.1 - 9.9e-64 214.5 0.0 1.8e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EMD58582.1 - 3.2e-41 140.1 0.2 4.9e-41 139.5 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EMD58582.1 - 2.5e-22 78.6 0.4 5.5e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EMD58582.1 - 1.7e-12 47.3 0.0 4.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD58582.1 - 8.9e-07 28.6 0.1 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Strabismus PF06638.6 EMD58583.1 - 0.046 12.0 0.2 0.063 11.5 0.1 1.1 1 0 0 1 1 1 0 Strabismus protein Shadoo PF14999.1 EMD58583.1 - 5 6.9 12.5 0.33 10.7 4.6 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Hexapep PF00132.19 EMD58584.1 - 5.3e-07 28.8 0.5 0.02 14.3 0.1 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMD58584.1 - 3.7e-05 23.8 0.0 6.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EMD58584.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase DUF4203 PF13886.1 EMD58587.1 - 0.0041 16.6 0.2 0.0065 15.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) zf-C2H2_6 PF13912.1 EMD58587.1 - 0.16 11.9 0.6 0.34 10.8 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger SnoaL PF07366.7 EMD58588.1 - 0.007 15.9 0.4 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase MBD_C PF14048.1 EMD58589.1 - 0.0061 17.1 3.7 0.011 16.3 0.5 3.1 2 1 1 3 3 3 1 C-terminal domain of methyl-CpG binding protein 2 and 3 Glyco_hydro_88 PF07470.8 EMD58590.1 - 6.4e-50 170.0 0.9 7.9e-50 169.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 EBP PF05241.7 EMD58591.1 - 5.8e-61 204.9 10.5 7.2e-61 204.5 7.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein Amidase PF01425.16 EMD58592.1 - 3.1e-96 322.9 0.0 3.6e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 EMD58593.1 - 9e-19 67.9 0.0 3.2e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD58593.1 - 3.5e-07 30.0 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD58593.1 - 2.5e-06 27.4 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD58593.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMD58593.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ATP-grasp_5 PF13549.1 EMD58593.1 - 0.059 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Syja_N PF02383.13 EMD58594.1 - 7e-93 310.8 0.0 1e-92 310.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EMD58594.1 - 2.8e-32 110.5 0.0 5.3e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Aldolase_II PF00596.16 EMD58596.1 - 3.3e-48 163.7 0.0 4.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peroxidase_2 PF01328.12 EMD58597.1 - 9.4e-13 47.5 0.1 2.9e-12 45.8 0.1 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 DUF3005 PF11448.3 EMD58598.1 - 0.26 10.9 2.0 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) DUF4153 PF13687.1 EMD58598.1 - 1.3 8.5 11.9 0.079 12.4 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) Pyridoxal_deC PF00282.14 EMD58599.1 - 4.1e-72 242.6 0.0 4.9e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans PF04082.13 EMD58600.1 - 2.8e-20 72.3 1.8 4.7e-20 71.5 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD58600.1 - 3.4e-07 30.0 14.2 7.2e-07 29.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med11 PF10280.4 EMD58600.1 - 0.047 13.7 0.4 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 Mediator complex protein Gemini_AC4_5 PF04807.7 EMD58602.1 - 0.16 11.4 0.4 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region adh_short PF00106.20 EMD58603.1 - 4.8e-23 81.8 4.7 4.8e-23 81.8 2.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD58603.1 - 2.2e-19 70.1 0.3 5.7e-19 68.8 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD58603.1 - 7.1e-10 38.8 0.8 1.5e-09 37.8 0.6 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD58603.1 - 1.7 8.5 10.7 9.1 6.1 0.5 3.5 2 2 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1989 PF09347.5 EMD58604.1 - 9e-50 168.3 0.0 1.4e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HMGL-like PF00682.14 EMD58605.1 - 9.4e-64 215.2 0.0 1.5e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EMD58605.1 - 1.1e-23 83.4 0.1 3.1e-23 82.0 0.1 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF2347 PF09804.4 EMD58606.1 - 2.9e-88 295.7 0.0 8.8e-88 294.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EMD58606.1 - 2.5e-29 102.6 3.6 2.5e-29 102.6 2.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.5 EMD58606.1 - 0.0002 21.0 0.0 0.00053 19.6 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EMD58606.1 - 0.0013 17.2 0.0 0.91 7.9 0.0 2.6 3 0 0 3 3 3 2 Transport protein Avl9 Sugar_tr PF00083.19 EMD58607.1 - 2.1e-106 356.2 16.9 2.6e-106 355.9 11.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD58607.1 - 3.4e-28 98.3 27.3 3.7e-27 94.9 11.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD58607.1 - 1.4e-08 33.6 10.7 2.9e-06 25.9 0.1 3.6 4 0 0 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 EMD58607.1 - 2e-05 22.9 0.6 2e-05 22.9 0.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EMD58607.1 - 6.3e-05 21.8 0.3 0.00012 20.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) LysM PF01476.15 EMD58608.1 - 2.2e-22 78.6 0.1 0.00012 21.8 0.0 5.7 6 0 0 6 6 6 4 LysM domain HTH_Tnp_1 PF01527.15 EMD58608.1 - 0.14 12.1 0.0 8.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Transposase Reprolysin_5 PF13688.1 EMD58609.1 - 0.00056 19.8 0.3 0.00094 19.1 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMD58609.1 - 0.0014 18.1 0.2 0.0022 17.5 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMD58609.1 - 0.0044 17.1 0.3 0.007 16.4 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF955 PF06114.8 EMD58609.1 - 0.011 15.3 0.3 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF955) Astacin PF01400.19 EMD58609.1 - 0.024 14.0 0.4 0.13 11.6 0.3 2.1 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 EMD58609.1 - 0.04 13.6 0.1 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EMD58609.1 - 0.13 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EMD58609.1 - 0.14 12.7 1.3 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMD58609.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Glyco_hydro_18 PF00704.23 EMD58610.1 - 1e-72 245.4 0.1 1.2e-72 245.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD58610.1 - 1.4e-08 34.5 4.9 1.4e-08 34.5 3.4 2.8 2 1 0 2 2 2 1 Chitin recognition protein Lipase_GDSL_2 PF13472.1 EMD58611.1 - 6.7e-13 49.1 0.2 6.9e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD58611.1 - 6.8e-06 26.0 0.0 3.8e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Arf PF00025.16 EMD58612.1 - 4.2e-41 140.0 0.0 5.5e-26 90.8 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EMD58612.1 - 5e-13 48.5 0.0 3.5e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMD58612.1 - 5.8e-12 45.3 0.0 8.6e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EMD58612.1 - 2.9e-07 29.8 0.0 3.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD58612.1 - 4.4e-07 30.4 0.0 6e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Miro-like protein SRPRB PF09439.5 EMD58612.1 - 5.6e-07 28.9 0.0 1.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMD58612.1 - 1.6e-05 24.4 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMD58612.1 - 2.6e-05 24.1 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD58612.1 - 0.028 13.7 0.1 0.062 12.5 0.1 1.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Sugar_tr PF00083.19 EMD58615.1 - 1.9e-18 66.3 8.8 2.1e-18 66.1 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD58615.1 - 0.0012 17.6 2.9 0.0014 17.4 2.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily YlaC PF10777.4 EMD58615.1 - 0.11 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC Glyco_hydro_cc PF11790.3 EMD58617.1 - 5.8e-65 219.0 0.0 7.1e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ribosomal_L22 PF00237.14 EMD58618.1 - 1.9e-34 117.7 0.9 5.6e-34 116.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 EMD58619.1 - 8.5e-107 355.2 0.0 1e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EMD58619.1 - 7e-05 22.4 0.0 9.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EMD58619.1 - 0.051 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Lactamase_B_2 PF12706.2 EMD58620.1 - 2.3e-29 102.3 0.9 1.1e-28 100.0 0.1 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EMD58620.1 - 8.8e-22 76.3 0.3 4.6e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease adh_short PF00106.20 EMD58620.1 - 4.5e-14 52.7 0.0 1.1e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD58620.1 - 7.4e-13 48.8 0.0 2.9e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.22 EMD58620.1 - 9.9e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 EMD58621.1 - 6.8e-06 25.8 9.2 1.4e-05 24.8 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2306 PF10067.4 EMD58622.1 - 7.4e-10 38.8 6.7 7.4e-10 38.8 4.7 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF997 PF06196.7 EMD58622.1 - 0.15 11.6 1.5 0.22 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) BTB_2 PF02214.17 EMD58623.1 - 9.6e-05 22.5 0.1 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GST_N PF02798.15 EMD58624.1 - 3.2e-10 40.0 0.0 1.1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMD58624.1 - 1.7e-08 34.5 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD58624.1 - 6.1e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD58624.1 - 2.1e-07 30.8 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD58624.1 - 0.00023 21.6 0.0 0.00048 20.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD58624.1 - 0.00089 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 EMD58625.1 - 0.033 13.9 0.1 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2839 PF10999.3 EMD58625.1 - 0.055 13.5 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Cupin_1 PF00190.17 EMD58626.1 - 3.5e-15 55.6 0.0 9.9e-15 54.2 0.0 1.8 2 1 0 2 2 2 1 Cupin Cupin_2 PF07883.6 EMD58626.1 - 0.00052 19.4 0.0 0.089 12.3 0.0 2.4 2 0 0 2 2 2 2 Cupin domain OGFr_N PF04664.8 EMD58627.1 - 7.2e-28 97.3 0.0 6.5e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region HSF_DNA-bind PF00447.12 EMD58627.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 HSF-type DNA-binding Alpha-amylase PF00128.19 EMD58628.1 - 1.4e-30 106.8 0.5 2.6e-30 105.9 0.3 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.11 EMD58629.1 - 2.2e-15 56.2 13.9 2.5e-15 56.0 8.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD58629.1 - 1e-08 34.2 2.2 1e-08 34.2 1.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Tropomyosin_1 PF12718.2 EMD58630.1 - 0.01 15.6 9.5 0.01 15.6 6.6 3.7 1 1 2 3 3 3 0 Tropomyosin like Ribosomal_S7 PF00177.16 EMD58631.1 - 1.1e-39 135.3 1.1 1.4e-39 135.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAM60A PF15396.1 EMD58632.1 - 1.2 8.8 4.1 2.6 7.7 2.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A RPE65 PF03055.10 EMD58633.1 - 1e-113 380.5 0.0 1.2e-113 380.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Med13_N PF11597.3 EMD58636.1 - 0.11 11.1 3.8 0.11 11.1 2.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Rep_fac-A_3 PF08661.6 EMD58636.1 - 0.11 12.4 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Replication factor A protein 3 Pex14_N PF04695.8 EMD58636.1 - 0.56 10.2 9.5 0.21 11.6 4.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EMD58636.1 - 1.5 7.0 5.4 1.8 6.7 3.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EMD58636.1 - 1.8 7.1 11.3 2.2 6.8 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF515 PF04415.7 EMD58636.1 - 1.9 6.6 6.9 2.9 6.0 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-RING_2 PF13639.1 EMD58638.1 - 3.1e-13 49.3 5.7 6.3e-13 48.3 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EMD58638.1 - 1.7e-08 34.0 3.8 4.1e-08 32.8 2.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMD58638.1 - 5.6e-08 32.6 6.1 1.1e-07 31.7 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD58638.1 - 9.1e-08 31.7 6.6 1.7e-07 30.8 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD58638.1 - 2e-07 30.5 6.5 3.5e-07 29.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD58638.1 - 2e-07 31.0 4.8 4.5e-07 29.8 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMD58638.1 - 1.1e-05 25.0 3.8 2.1e-05 24.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD58638.1 - 3.4e-05 23.6 5.0 6.6e-05 22.7 3.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMD58638.1 - 0.00066 19.4 4.0 0.0016 18.2 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EMD58638.1 - 0.12 11.9 3.8 0.22 11.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EMD58638.1 - 0.24 11.0 2.9 0.56 9.8 2.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EMD58638.1 - 0.26 11.3 5.4 0.14 12.2 1.8 2.1 2 1 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.1 EMD58638.1 - 0.88 9.3 7.4 0.048 13.4 1.1 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Isochorismatase PF00857.15 EMD58639.1 - 5.1e-40 137.2 0.1 5.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family 5_3_exonuc_N PF02739.11 EMD58639.1 - 0.052 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Myb_CC_LHEQLE PF14379.1 EMD58640.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif L_biotic_typeA PF04604.8 EMD58641.1 - 0.036 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic Glyco_hydro_11 PF00457.12 EMD58642.1 - 1.1e-76 256.2 24.2 1.3e-76 255.9 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ALO PF04030.9 EMD58643.1 - 1.8e-84 283.4 1.4 2.5e-84 282.8 0.9 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EMD58643.1 - 5.1e-32 110.2 0.1 7.6e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SSPI PF14098.1 EMD58644.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore protein I NRDE-2 PF08424.5 EMD58645.1 - 3.4e-80 269.3 0.0 3.5e-78 262.7 0.0 2.5 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EMD58645.1 - 0.0028 18.1 7.5 21 6.0 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat Nucleoplasmin PF03066.10 EMD58645.1 - 0.038 13.4 0.9 0.074 12.5 0.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin BP28CT PF08146.7 EMD58646.1 - 5.5e-39 133.3 2.3 4e-38 130.5 1.6 2.7 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EMD58646.1 - 3.9e-23 81.6 2.8 3.9e-23 81.6 2.0 5.2 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EMD58646.1 - 6e-06 25.9 15.9 0.0096 15.9 0.1 9.0 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 EMD58646.1 - 0.0033 17.8 11.0 1.7 9.2 0.3 7.5 6 1 1 7 7 7 1 HEAT-like repeat Arm PF00514.18 EMD58646.1 - 8 6.4 11.8 9.9 6.1 0.3 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Fungal_trans PF04082.13 EMD58647.1 - 2.6e-30 105.1 0.0 1.3e-28 99.5 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD58647.1 - 1.8e-07 30.9 9.0 3e-07 30.2 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EMD58647.1 - 7.1 6.8 11.2 17 5.6 7.8 1.6 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ATP12 PF07542.6 EMD58648.1 - 5e-35 120.1 0.5 8.9e-35 119.2 0.3 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EMD58649.1 - 3.6e-131 436.8 0.0 3.6e-131 436.8 0.0 2.3 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_2 PF12796.2 EMD58649.1 - 8e-21 74.1 0.1 5.5e-09 36.2 0.0 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD58649.1 - 1.5e-20 72.7 0.4 2.2e-12 46.7 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMD58649.1 - 2.2e-15 55.5 1.1 8.3e-07 28.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMD58649.1 - 5.9e-15 55.3 0.1 7e-07 29.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EMD58649.1 - 1.5e-12 47.6 0.4 3.4e-12 46.4 0.3 1.7 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 EMD58649.1 - 8e-12 44.1 0.0 0.00026 20.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.1 EMD58649.1 - 2.9e-10 40.3 1.2 2.9e-10 40.3 0.8 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EMD58649.1 - 2.6e-07 30.5 1.1 8.6e-07 28.9 0.7 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Amidase PF01425.16 EMD58650.1 - 1.7e-68 231.4 0.2 6.3e-63 213.1 0.0 2.4 2 1 1 3 3 3 2 Amidase CAP59_mtransfer PF11735.3 EMD58651.1 - 4.7e-90 301.0 0.0 1e-89 299.9 0.0 1.5 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Glyco_transf_90 PF05686.7 EMD58653.1 - 1.2e-12 47.2 1.0 2.5e-10 39.6 0.5 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Cytochrom_B_N PF00033.14 EMD58655.1 - 0.042 13.1 0.6 0.33 10.2 0.7 1.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DOR PF14839.1 EMD58656.1 - 6.8 6.3 9.7 16 5.1 6.7 1.6 1 1 0 1 1 1 0 DOR family FUSC PF04632.7 EMD58657.1 - 1.7 6.9 5.2 2.2 6.6 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF445 PF04286.7 EMD58657.1 - 2.9 7.3 8.3 4.5 6.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TMF_DNA_bd PF12329.3 EMD58657.1 - 3.3 7.5 13.1 0.93 9.3 0.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EF-hand_1 PF00036.27 EMD58658.1 - 2.9e-26 88.7 12.3 8.8e-07 27.7 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMD58658.1 - 1.2e-23 82.9 3.5 1.2e-12 47.7 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMD58658.1 - 3.5e-20 70.0 5.8 3.9e-05 23.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMD58658.1 - 1.1e-18 65.6 12.8 2.4e-06 26.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMD58658.1 - 1.7e-15 56.3 12.9 1.9e-05 24.1 0.7 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMD58658.1 - 1.8e-06 27.9 0.0 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMD58658.1 - 5.2e-06 26.1 6.7 0.0027 17.4 0.3 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMD58658.1 - 0.026 14.4 0.1 1.6 8.6 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain PMBR PF09373.5 EMD58658.1 - 0.14 12.2 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF1770 PF08589.5 EMD58659.1 - 9.4e-27 93.5 0.2 1.6e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SNF2_N PF00176.18 EMD58660.1 - 1.1e-65 221.3 0.0 1.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD58660.1 - 1.2e-11 44.2 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD58660.1 - 1.1e-06 28.2 0.0 3.4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EMD58660.1 - 5.9e-06 25.3 0.2 1.6e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMD58660.1 - 0.00039 20.3 0.0 0.00099 18.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNR_inhib PF08591.5 EMD58662.1 - 1.4e-15 58.0 0.0 4.8e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor MARVEL PF01284.18 EMD58663.1 - 0.0021 17.8 2.7 0.0033 17.2 1.6 1.5 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_A24 PF01478.13 EMD58663.1 - 0.0022 18.1 0.7 0.0068 16.5 0.5 1.9 1 1 0 1 1 1 1 Type IV leader peptidase family PMP1_2 PF08114.6 EMD58663.1 - 0.028 13.8 0.3 0.028 13.8 0.2 1.9 2 0 0 2 2 2 0 ATPase proteolipid family DUF2976 PF11190.3 EMD58663.1 - 0.58 9.7 0.0 0.58 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) BPD_transp_1 PF00528.17 EMD58663.1 - 0.67 9.4 11.6 4.4 6.7 4.2 2.8 1 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component DUF996 PF06195.8 EMD58663.1 - 5.5 6.9 7.5 31 4.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF996) UBA_4 PF14555.1 EMD58664.1 - 0.00043 19.7 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 EMD58664.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 LysM domain Baculo_IE-1 PF05290.6 EMD58664.1 - 0.12 12.1 1.4 0.21 11.3 1.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ribosomal_S8 PF00410.14 EMD58665.1 - 1e-26 93.2 0.1 1.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 AAA_2 PF07724.9 EMD58666.1 - 4.3e-47 160.1 0.0 2.5e-45 154.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMD58666.1 - 4.9e-27 94.7 0.0 1.8e-14 54.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMD58666.1 - 1.9e-23 82.1 0.2 7.3e-23 80.2 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EMD58666.1 - 1.1e-16 61.4 3.2 1.3e-05 25.2 0.0 5.4 3 2 3 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EMD58666.1 - 1.7e-15 57.0 0.4 1.2e-09 38.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD58666.1 - 1.1e-13 51.4 0.1 6.4e-05 23.0 0.0 4.0 2 2 1 3 3 3 2 AAA domain Clp_N PF02861.15 EMD58666.1 - 2.1e-10 40.3 0.3 0.00033 20.5 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 EMD58666.1 - 1.9e-08 33.9 0.0 3e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EMD58666.1 - 1.3e-07 32.4 7.2 0.012 16.4 0.0 4.2 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EMD58666.1 - 5.4e-07 29.2 0.0 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMD58666.1 - 1.9e-06 27.4 4.7 0.015 15.0 0.2 3.6 4 0 0 4 4 3 2 Part of AAA domain AAA_18 PF13238.1 EMD58666.1 - 3.2e-06 27.4 6.0 0.011 16.0 0.0 4.3 3 2 0 4 4 3 2 AAA domain AAA_28 PF13521.1 EMD58666.1 - 1.6e-05 24.9 1.6 0.33 10.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EMD58666.1 - 1.7e-05 24.0 0.0 0.13 11.4 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMD58666.1 - 4.2e-05 23.4 0.2 0.2 11.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EMD58666.1 - 5.7e-05 23.2 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.6 EMD58666.1 - 0.0001 21.9 0.0 0.52 9.9 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMD58666.1 - 0.00013 21.7 5.8 0.8 9.3 0.0 4.9 5 1 1 6 6 4 2 Archaeal ATPase MobB PF03205.9 EMD58666.1 - 0.00013 21.6 0.0 0.79 9.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EMD58666.1 - 0.0004 19.5 0.1 0.037 13.1 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin T2SE PF00437.15 EMD58666.1 - 0.00051 19.0 0.0 0.032 13.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EMD58666.1 - 0.0006 19.2 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD58666.1 - 0.00073 18.9 1.2 1.8 7.9 0.0 3.6 3 1 1 4 4 3 2 AAA domain Torsin PF06309.6 EMD58666.1 - 0.0008 19.2 0.0 0.0087 15.9 0.0 2.4 3 0 0 3 3 2 1 Torsin ABC_tran PF00005.22 EMD58666.1 - 0.0008 19.7 1.6 0.76 10.0 0.0 3.5 4 0 0 4 4 3 1 ABC transporter DUF258 PF03193.11 EMD58666.1 - 0.0011 18.2 0.0 0.68 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 EMD58666.1 - 0.0016 18.3 0.8 0.2 11.5 0.0 3.9 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EMD58666.1 - 0.002 17.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EMD58666.1 - 0.0049 16.5 0.0 0.22 11.1 0.0 3.0 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 EMD58666.1 - 0.0049 16.5 0.0 0.5 10.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EMD58666.1 - 0.01 15.3 0.0 2.1 7.7 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1192 PF06698.6 EMD58666.1 - 0.012 15.3 8.4 0.02 14.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) AAA_21 PF13304.1 EMD58666.1 - 0.029 14.3 0.0 2.2 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EMD58666.1 - 0.044 13.4 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EMD58666.1 - 0.11 11.8 9.9 0.5 9.7 0.0 4.6 4 2 2 6 6 5 0 AAA-like domain Occludin_ELL PF07303.8 EMD58666.1 - 0.14 12.9 7.4 0.24 12.1 3.5 2.6 2 0 0 2 2 1 0 Occludin homology domain AAA_23 PF13476.1 EMD58666.1 - 1.6 8.9 0.0 1.6 8.9 0.0 4.4 3 2 0 4 4 3 0 AAA domain Sec63 PF02889.11 EMD58668.1 - 2.7e-46 158.2 0.0 7.6e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 EMD58668.1 - 4e-16 58.5 0.2 9.1e-16 57.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 EMD58669.1 - 1.1e-47 162.3 0.0 8.6e-45 152.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58669.1 - 1.4e-30 106.2 0.0 3.2e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EMD58669.1 - 0.0026 16.6 0.1 0.004 16.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 EMD58669.1 - 0.0038 16.2 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMD58669.1 - 0.19 10.4 0.1 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EMD58670.1 - 6.8e-63 212.0 0.1 2.2e-62 210.3 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Mem_trans PF03547.13 EMD58670.1 - 5.3e-46 156.6 0.2 5.3e-46 156.6 0.2 1.8 2 1 0 2 2 2 1 Membrane transport protein Choline_kin_N PF04428.9 EMD58670.1 - 1.6e-17 62.6 0.2 5.7e-17 60.9 0.1 2.1 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 EMD58670.1 - 9.1e-06 25.5 0.1 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mis12 PF05859.7 EMD58671.1 - 2.7e-34 118.0 0.0 4.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Pol_alpha_B_N PF08418.5 EMD58671.1 - 1.2 8.6 9.8 1.8 8.0 6.8 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 EMD58672.1 - 1e-58 198.5 0.6 1.7e-58 197.8 0.1 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58672.1 - 2.3e-20 72.7 0.0 5.9e-19 68.1 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.16 EMD58673.1 - 3.7e-77 259.4 0.1 4.4e-77 259.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Romo1 PF10247.4 EMD58673.1 - 0.66 10.2 3.1 25 5.1 0.0 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 SRP19 PF01922.12 EMD58674.1 - 2.5e-29 101.6 0.0 4.2e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Asp PF00026.18 EMD58675.1 - 5.2e-69 232.9 10.9 6.2e-69 232.6 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMD58675.1 - 1.3e-06 28.7 0.3 0.00052 20.4 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EMD58675.1 - 0.00011 22.1 2.1 0.00028 20.8 0.5 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DUF1849 PF08904.6 EMD58675.1 - 0.084 12.1 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DEAD PF00270.24 EMD58676.1 - 7.5e-33 113.3 0.2 3.1e-16 59.3 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD58676.1 - 3.6e-21 74.8 0.0 1e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD58676.1 - 9.3e-06 25.5 4.3 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMD58676.1 - 0.018 13.4 0.0 3.6 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 EMD58676.1 - 0.039 13.2 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain PIGA PF08288.7 EMD58677.1 - 6.8e-48 160.9 0.9 6.8e-48 160.9 0.6 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EMD58677.1 - 3.9e-27 94.7 0.0 6.2e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMD58677.1 - 6.9e-18 64.9 0.8 1.2e-17 64.2 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EMD58677.1 - 6.7e-16 58.6 0.1 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMD58677.1 - 6.7e-15 55.5 0.0 1.6e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EMD58677.1 - 8.3e-05 22.7 0.0 0.00027 21.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EMD58677.1 - 0.00083 19.2 0.2 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 EMD58677.1 - 0.013 14.9 0.1 0.031 13.7 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain DUF3455 PF11937.3 EMD58678.1 - 3.8e-41 140.9 0.9 4.6e-41 140.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CASP_C PF08172.7 EMD58679.1 - 5.4e-84 281.0 0.0 5.4e-84 281.0 0.0 3.7 2 1 2 4 4 4 1 CASP C terminal CtIP_N PF10482.4 EMD58679.1 - 0.0025 17.5 0.1 0.0025 17.5 0.0 4.9 4 2 0 4 4 4 1 Tumour-suppressor protein CtIP N-terminal domain DUF904 PF06005.7 EMD58679.1 - 0.061 13.6 0.1 0.061 13.6 0.1 6.5 4 3 0 4 4 4 0 Protein of unknown function (DUF904) IncA PF04156.9 EMD58679.1 - 1.4 8.5 59.1 2.7 7.5 0.0 5.5 3 1 0 4 4 4 0 IncA protein Mago_nashi PF02792.9 EMD58679.1 - 3.2 7.4 8.2 0.64 9.7 1.2 2.7 2 1 0 2 2 2 0 Mago nashi protein Vps39_2 PF10367.4 EMD58680.1 - 6.7e-09 35.9 0.0 6.4e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EMD58680.1 - 5.6e-08 32.5 0.1 8.7e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_1 PF10366.4 EMD58680.1 - 0.0057 16.6 0.2 0.94 9.5 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Reg_prop PF07494.6 EMD58680.1 - 0.12 12.4 0.3 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller Prefoldin_2 PF01920.15 EMD58681.1 - 2.2e-22 78.8 3.7 3e-22 78.3 2.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit AATF-Che1 PF13339.1 EMD58681.1 - 0.054 13.6 1.8 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2353 PF09789.4 EMD58681.1 - 0.077 12.2 7.0 4.4 6.4 4.2 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) AAA_23 PF13476.1 EMD58681.1 - 0.22 11.8 6.0 0.29 11.4 4.1 1.2 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 EMD58681.1 - 0.31 10.9 5.1 0.42 10.5 0.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3782 PF12644.2 EMD58681.1 - 6.9 6.5 10.0 3.7e+02 1.0 6.9 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) MFS_1 PF07690.11 EMD58682.1 - 1.5e-41 142.3 37.4 1.5e-41 142.3 25.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD58682.1 - 1.2e-08 34.0 30.2 4.2e-08 32.2 20.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter NAD_binding_5 PF07994.7 EMD58682.1 - 0.08 12.4 0.6 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase OATP PF03137.15 EMD58682.1 - 0.59 8.1 9.7 0.023 12.7 0.9 2.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family PhyH PF05721.8 EMD58683.1 - 1.6e-06 28.3 0.5 4.8e-06 26.7 0.1 2.0 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_S25 PF03297.10 EMD58684.1 - 1.4e-38 131.1 4.8 1.5e-38 131.0 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.15 EMD58684.1 - 0.036 14.1 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.7 EMD58684.1 - 0.042 13.3 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.7 EMD58684.1 - 0.057 13.0 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 EMD58684.1 - 0.058 13.0 0.1 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 MarR family NAD4L PF06235.6 EMD58687.1 - 0.58 9.9 4.1 0.7 9.7 2.9 1.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Herpes_UL45 PF05473.7 EMD58688.1 - 0.034 13.5 0.1 0.093 12.1 0.0 1.7 1 0 0 1 1 1 0 UL45 protein Cyt-b5 PF00173.23 EMD58689.1 - 1.7e-09 37.3 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EMD58690.1 - 2.2e-72 242.9 0.0 3.1e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EMD58690.1 - 2.8e-05 23.4 0.0 4.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD58690.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EMD58690.1 - 0.0046 17.4 0.0 0.0092 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD58690.1 - 0.0093 15.9 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMD58690.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EMD58690.1 - 0.018 14.9 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMD58690.1 - 0.13 12.2 1.0 1 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF2834 PF11196.3 EMD58691.1 - 0.25 11.5 0.1 0.25 11.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2834) AT_hook PF02178.14 EMD58691.1 - 0.57 10.0 4.2 1.3 8.9 2.9 1.6 1 0 0 1 1 1 0 AT hook motif DUF2721 PF11026.3 EMD58691.1 - 5.1 6.7 8.2 4.2 7.0 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) BCNT PF07572.7 EMD58692.1 - 1.7e-24 85.5 0.4 3.7e-24 84.4 0.3 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development RdRP PF05183.7 EMD58693.1 - 3.6e-125 418.8 0.1 5.1e-125 418.4 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase TCTP PF00838.12 EMD58694.1 - 4.3e-63 212.1 2.0 4.9e-63 212.0 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.8 EMD58695.1 - 1.4e-16 60.9 11.9 1.4e-16 60.9 8.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily VWA PF00092.23 EMD58697.1 - 5e-10 39.3 0.0 4.8e-09 36.1 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EMD58697.1 - 3.1e-08 33.9 0.0 6.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EMD58697.1 - 6.2e-05 22.9 0.0 8.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF98 PF01947.11 EMD58699.1 - 0.056 13.1 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF98) Iso_dh PF00180.15 EMD58700.1 - 2.4e-124 414.8 0.0 2.7e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HET PF06985.6 EMD58703.1 - 1.6e-21 76.9 0.0 4.1e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S10 PF00450.17 EMD58704.1 - 3.1e-131 438.3 1.9 3.8e-131 438.0 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EMD58704.1 - 8.7e-11 41.9 0.2 1.5e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EMD58704.1 - 0.0061 16.4 0.0 0.025 14.4 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family SBDS_C PF09377.5 EMD58705.1 - 9.2e-49 164.3 0.5 2.1e-48 163.1 0.4 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EMD58705.1 - 2.8e-29 100.7 1.2 5.1e-29 99.9 0.8 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Tim54 PF11711.3 EMD58706.1 - 0.068 11.7 2.1 0.084 11.4 1.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 IFT57 PF10498.4 EMD58706.1 - 0.1 11.3 4.1 0.14 10.9 2.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GET2 PF08690.5 EMD58706.1 - 7.6 5.6 7.7 11 5.1 5.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Ribosomal_S13 PF00416.17 EMD58707.1 - 7.2e-40 135.7 1.2 8.9e-40 135.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EMD58707.1 - 0.0068 15.0 0.0 0.0073 14.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EMD58707.1 - 0.044 13.7 0.8 0.096 12.7 0.5 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SnoaL PF07366.7 EMD58710.1 - 8.8e-05 22.0 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD58710.1 - 0.017 15.5 0.0 0.06 13.7 0.0 2.0 2 2 0 2 2 2 0 SnoaL-like domain PAP_central PF04928.12 EMD58712.1 - 1.5e-98 328.6 0.0 1.9e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EMD58712.1 - 2.9e-37 127.5 0.0 5.9e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EMD58712.1 - 1.5e-08 34.8 0.0 4.7e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain YlbD_coat PF14071.1 EMD58712.1 - 0.05 13.6 0.2 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein 2_5_RNA_ligase2 PF13563.1 EMD58713.1 - 4.9e-12 45.8 0.1 5.5e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Abhydrolase_1 PF00561.15 EMD58714.1 - 1.3e-13 51.0 0.2 3.9e-13 49.4 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD58714.1 - 5e-10 39.6 0.0 8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD58714.1 - 0.023 14.4 0.1 0.087 12.5 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family MatE PF01554.13 EMD58715.1 - 2.7e-52 176.6 31.8 3.4e-29 101.5 7.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMD58715.1 - 0.00091 19.0 17.1 0.00091 19.0 11.8 4.0 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4512 PF14975.1 EMD58715.1 - 0.025 15.4 0.0 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) E1-E2_ATPase PF00122.15 EMD58716.1 - 2.2e-44 151.1 3.2 5.5e-44 149.9 2.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD58716.1 - 1.1e-36 126.1 5.3 1.1e-36 126.1 3.7 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD58716.1 - 5.6e-29 102.0 0.0 2.3e-28 100.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD58716.1 - 1e-19 70.2 0.0 2.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD58716.1 - 6.5e-14 52.5 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD58716.1 - 0.11 12.0 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HALZ PF02183.13 EMD58719.1 - 0.0038 16.9 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.10 EMD58719.1 - 0.0063 15.9 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 EMD58719.1 - 0.013 15.7 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Herpes_BLRF2 PF05812.7 EMD58719.1 - 0.014 15.1 0.1 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Filament PF00038.16 EMD58719.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein TSC22 PF01166.13 EMD58719.1 - 0.053 13.4 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 EMD58719.1 - 0.079 13.3 0.0 0.079 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 EMD58719.1 - 0.16 11.6 0.3 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain ERGIC_N PF13850.1 EMD58721.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3624 PF12292.3 EMD58721.1 - 0.15 12.5 0.6 0.18 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Zn_clus PF00172.13 EMD58721.1 - 0.16 11.8 6.5 0.48 10.3 4.5 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 EMD58721.1 - 1 9.4 5.6 0.96 9.5 3.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) CENP-F_C_Rb_bdg PF10490.4 EMD58722.1 - 0.19 11.0 0.6 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF3157 PF11355.3 EMD58723.1 - 0.099 11.9 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) RGS PF00615.14 EMD58723.1 - 0.13 12.3 0.1 0.15 12.1 0.1 1.0 1 0 0 1 1 1 0 Regulator of G protein signaling domain F5_F8_type_C PF00754.20 EMD58727.1 - 2e-08 34.1 1.5 2.6e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain GAT PF03127.9 EMD58729.1 - 9.9e-12 44.7 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EMD58729.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 VHS domain DUF2183 PF09949.4 EMD58730.1 - 2.2e-28 98.1 0.0 4.3e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Cytochrom_B561 PF03188.11 EMD58732.1 - 4.8e-07 29.6 11.7 2.3e-06 27.4 8.3 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EMD58732.1 - 3.7e-05 23.2 4.5 0.00018 21.0 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) PDEase_II PF02112.10 EMD58733.1 - 6e-51 173.3 0.0 9.3e-23 80.6 0.0 3.7 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II EF1G PF00647.14 EMD58733.1 - 1.6e-44 150.0 0.1 2.7e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EMD58733.1 - 1e-11 44.6 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD58733.1 - 1.1e-11 44.6 0.0 5.1e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMD58733.1 - 6.5e-10 39.1 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD58733.1 - 8.6e-10 38.3 0.6 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD58733.1 - 1.5e-07 31.8 0.1 1.3e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD58733.1 - 0.0019 18.1 0.0 0.0053 16.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lactamase_B_2 PF12706.2 EMD58733.1 - 0.019 14.4 0.2 0.1 12.1 0.1 2.3 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Ribosomal_S9 PF00380.14 EMD58734.1 - 1.3e-36 125.5 0.1 2.1e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HEAT_EZ PF13513.1 EMD58734.1 - 0.038 14.4 0.1 15 6.2 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat COX6C PF02937.10 EMD58737.1 - 0.16 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc EHN PF06441.7 EMD58739.1 - 6.8e-33 112.9 0.2 1.2e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EMD58739.1 - 9.8e-08 31.8 0.0 2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD58739.1 - 1.5e-06 28.2 0.1 7.1e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_76 PF03663.9 EMD58740.1 - 1.1e-138 462.6 10.5 1.4e-138 462.3 7.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Bim_N PF06773.6 EMD58741.1 - 0.52 10.1 3.2 4.3 7.1 2.2 2.2 1 1 0 1 1 1 0 Bim protein N-terminus zf-C2H2 PF00096.21 EMD58743.1 - 0.018 15.3 3.9 0.018 15.3 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.4 EMD58744.1 - 2.1e-62 210.8 0.0 3.4e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EMD58744.1 - 5.8e-21 74.8 2.4 1.1e-20 74.0 1.7 1.4 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EMD58744.1 - 0.04 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 TPR repeat Pkinase PF00069.20 EMD58745.1 - 9.6e-07 28.2 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.19 EMD58745.1 - 0.0012 18.4 0.7 0.0022 17.6 0.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PfkB PF00294.19 EMD58746.1 - 4.2e-72 242.8 0.4 5e-72 242.5 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMD58746.1 - 5.8e-06 25.6 0.0 2.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase UBX PF00789.15 EMD58747.1 - 3.4e-12 46.2 0.0 8.3e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMD58747.1 - 2.5e-10 39.6 0.2 5.8e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain CAF-1_p150 PF11600.3 EMD58747.1 - 0.0051 16.2 13.7 0.0093 15.3 9.5 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med19 PF10278.4 EMD58747.1 - 0.086 12.5 2.9 0.15 11.7 2.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Tom37_C PF11801.3 EMD58747.1 - 3.3 7.5 9.8 6.3 6.6 6.8 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DDRGK PF09756.4 EMD58747.1 - 5 6.4 17.4 9.3 5.6 12.1 1.3 1 0 0 1 1 1 0 DDRGK domain MFS_1 PF07690.11 EMD58748.1 - 1.1e-28 100.0 42.2 1.8e-28 99.3 29.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 EMD58748.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SPRY PF00622.23 EMD58749.1 - 3.1e-19 69.2 0.1 5.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain HEAT PF02985.17 EMD58750.1 - 1.3e-26 90.2 6.5 0.0011 18.8 0.0 10.4 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EMD58750.1 - 1.5e-26 92.1 17.3 1.4e-11 44.5 0.0 10.9 12 2 2 14 14 13 5 HEAT-like repeat HEAT_2 PF13646.1 EMD58750.1 - 9.9e-23 80.2 1.5 3.9e-08 33.4 0.0 7.6 3 3 5 8 8 8 4 HEAT repeats Cnd1 PF12717.2 EMD58750.1 - 8.6e-13 48.5 0.0 0.00047 20.0 0.0 5.9 6 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMD58750.1 - 9.8e-12 45.1 0.0 0.05 13.9 0.0 6.7 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EMD58750.1 - 2e-08 33.3 0.1 0.081 11.6 0.0 4.1 4 0 0 4 4 4 3 RNAPII transcription regulator C-terminal Arm PF00514.18 EMD58750.1 - 6.1e-08 32.2 1.5 1.1 9.1 0.0 6.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EMD58750.1 - 4.2e-06 26.2 0.2 30 3.8 0.0 6.8 6 2 1 8 8 8 0 CLASP N terminal IBN_N PF03810.14 EMD58750.1 - 1.6e-05 24.6 0.3 0.0013 18.5 0.0 3.8 2 1 1 3 3 3 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 EMD58750.1 - 0.013 15.4 0.0 0.92 9.5 0.0 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 EMD58750.1 - 0.015 15.2 0.0 1.9 8.3 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein Cohesin_HEAT PF12765.2 EMD58750.1 - 0.046 13.7 0.0 1.6 8.7 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF1546 PF07571.8 EMD58750.1 - 0.049 13.7 0.1 22 5.2 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 EMD58750.1 - 0.093 13.2 3.7 64 4.4 0.0 5.0 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat PBP1_TM PF14812.1 EMD58751.1 - 0.00047 20.4 4.3 0.00085 19.5 3.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Serglycin PF04360.7 EMD58751.1 - 0.012 15.3 0.5 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Serglycin DUF4604 PF15377.1 EMD58751.1 - 0.26 11.4 4.0 0.4 10.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF543 PF04418.7 EMD58751.1 - 6.2 6.8 9.5 12 5.9 1.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Zn_clus PF00172.13 EMD58752.1 - 1.8e-08 34.1 11.8 2.9e-08 33.4 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD58752.1 - 1.7e-07 30.1 1.6 3e-07 29.4 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAGE_N PF12440.3 EMD58752.1 - 0.84 9.9 9.4 7.4 6.9 0.1 2.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Peptidase_C12 PF01088.16 EMD58754.1 - 6e-69 231.4 0.0 8.4e-69 230.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 EMP24_GP25L PF01105.19 EMD58755.1 - 0.53 9.9 3.1 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Z1 PF10593.4 EMD58755.1 - 2.4 7.3 5.8 4.4 6.4 4.0 1.5 1 0 0 1 1 1 0 Z1 domain Nop53 PF07767.6 EMD58755.1 - 4.7 6.1 34.9 9.7 5.0 24.2 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HSP70 PF00012.15 EMD58756.1 - 5.3e-63 212.8 11.4 6e-60 202.7 0.2 3.7 3 1 0 3 3 3 2 Hsp70 protein MutS_III PF05192.13 EMD58756.1 - 0.063 13.0 9.1 0.12 12.1 5.4 2.2 2 1 0 2 2 2 0 MutS domain III FGGY_C PF02782.11 EMD58756.1 - 0.072 12.6 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Clp_N PF02861.15 EMD58756.1 - 6 6.8 8.3 22 5.0 0.0 4.1 4 0 0 4 4 4 0 Clp amino terminal domain Mtc PF03820.12 EMD58757.1 - 4.2e-107 357.3 0.1 1.1e-106 356.0 0.0 1.6 1 1 0 1 1 1 1 Tricarboxylate carrier Aminotran_1_2 PF00155.16 EMD58759.1 - 1.7e-17 63.4 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMD58759.1 - 0.033 12.7 0.0 0.67 8.4 0.0 2.3 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.2 EMD58761.1 - 5e-82 275.3 15.6 6.2e-67 226.0 6.7 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMD58761.1 - 7.7e-07 28.4 2.5 0.0043 16.4 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase WD40 PF00400.27 EMD58762.1 - 1.3e-139 449.7 78.3 1e-14 53.7 0.6 11.9 12 0 0 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 EMD58762.1 - 3.1e-28 98.5 0.1 5.8e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD58762.1 - 5.9e-21 75.0 9.9 6.6e-21 74.9 2.9 3.4 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD58762.1 - 2.7e-19 68.7 48.7 0.0036 15.5 0.2 10.6 1 1 10 11 11 11 10 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EMD58762.1 - 1.5e-13 50.4 0.1 0.2 10.9 0.1 7.1 1 1 7 8 8 8 6 Cytolethal distending toxin A/C family Asp_decarbox PF02261.11 EMD58762.1 - 0.00016 21.1 0.0 95 2.6 0.0 7.3 2 2 6 8 8 8 0 Aspartate decarboxylase AAA_16 PF13191.1 EMD58762.1 - 0.0024 17.9 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Me-amine-dh_H PF06433.6 EMD58762.1 - 0.0039 15.8 1.2 3.8 6.0 0.0 4.0 1 1 3 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) AAA_19 PF13245.1 EMD58762.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Nol1_Nop2_Fmu PF01189.12 EMD58763.1 - 1.7e-17 63.7 0.1 5.2e-13 49.0 0.0 2.7 3 0 0 3 3 3 2 NOL1/NOP2/sun family SAD_SRA PF02182.12 EMD58764.1 - 0.00079 18.7 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain AA_permease_2 PF13520.1 EMD58765.1 - 1e-43 149.4 49.6 1.4e-43 149.0 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD58765.1 - 1.5e-24 86.2 46.5 1.9e-24 85.8 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 EMD58765.1 - 0.15 11.7 0.2 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) CTV_P6 PF06706.6 EMD58765.1 - 1 8.8 7.4 0.34 10.4 0.3 3.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein NACHT PF05729.7 EMD58768.1 - 2.8e-06 27.0 0.3 9.8e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EMD58768.1 - 1.1e-05 25.5 0.1 0.00073 19.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMD58768.1 - 0.00015 20.8 2.7 0.0038 16.2 0.1 2.4 1 1 1 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.1 EMD58768.1 - 0.00082 19.4 0.1 0.044 13.7 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EMD58768.1 - 0.0019 17.9 0.0 0.0069 16.1 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EMD58768.1 - 0.0023 16.8 0.2 0.0061 15.4 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 EMD58768.1 - 0.0034 17.5 0.2 0.11 12.7 0.0 2.7 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.1 EMD58768.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMD58768.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 1 0 1 1 1 0 KaiC AAA_29 PF13555.1 EMD58768.1 - 0.069 12.6 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EMD58768.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EMD58768.1 - 0.17 12.1 1.6 0.95 9.7 0.1 2.6 2 1 1 3 3 3 0 ABC transporter CDO_I PF05995.7 EMD58769.1 - 6.7e-40 136.1 0.0 8.5e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EMD58769.1 - 0.00017 21.0 0.6 0.00027 20.3 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 EMD58770.1 - 9.7e-23 79.7 0.1 2.6e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMD58770.1 - 6.3e-19 68.0 0.2 1.8e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD58770.1 - 5e-10 38.8 0.1 2.7e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMD58770.1 - 0.0001 22.1 0.3 0.019 14.7 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EMD58770.1 - 0.00027 20.4 2.2 1.1 8.6 0.0 4.1 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EMD58770.1 - 0.0037 17.7 0.0 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EMD58770.1 - 0.0043 15.8 0.1 0.012 14.4 0.1 1.7 1 0 0 1 1 1 1 ArgK protein AIG1 PF04548.11 EMD58770.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF211 PF02680.9 EMD58770.1 - 0.087 12.6 0.1 0.39 10.5 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Arf PF00025.16 EMD58770.1 - 0.1 11.8 0.2 2 7.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 EMD58771.1 - 4.6e-15 55.1 0.2 8e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EMD58771.1 - 2e-07 30.3 0.0 5.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EMD58771.1 - 0.025 14.2 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.1 EMD58771.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EMD58771.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EMD58771.1 - 0.063 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EMD58771.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EMD58771.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain MarR_2 PF12802.2 EMD58771.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF2650 PF10853.3 EMD58772.1 - 0.21 11.0 3.5 0.43 10.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) DUF2207 PF09972.4 EMD58772.1 - 1.2 7.6 5.4 1.3 7.5 3.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PXA PF02194.10 EMD58775.1 - 9.6e-42 142.6 0.0 1.7e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 PXA domain DUF3538 PF12057.3 EMD58775.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Nexin_C PF08628.7 EMD58775.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal Med10 PF09748.4 EMD58776.1 - 2e-32 111.7 2.6 2.3e-32 111.4 1.8 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Flagellin_N PF00669.15 EMD58776.1 - 0.00043 20.0 0.9 0.001 18.8 0.2 1.8 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region DUF3877 PF12993.2 EMD58776.1 - 0.00048 19.7 0.0 0.00069 19.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF86 PF01934.12 EMD58776.1 - 0.003 17.2 0.2 0.0038 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF86 GP41 PF00517.12 EMD58776.1 - 0.011 15.3 1.8 2.2 7.8 0.1 2.1 2 0 0 2 2 2 0 Retroviral envelope protein ApoLp-III PF07464.6 EMD58776.1 - 0.041 13.9 1.3 6.4 6.7 0.2 2.5 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) D123 PF07065.9 EMD58776.1 - 0.054 12.5 0.1 0.14 11.2 0.0 1.6 1 1 1 2 2 2 0 D123 ROS_MUCR PF05443.6 EMD58776.1 - 0.073 12.8 0.2 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein MinE PF03776.9 EMD58776.1 - 0.077 12.5 0.4 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE Nup54 PF13874.1 EMD58776.1 - 0.23 11.1 2.3 0.3 10.7 0.3 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Glyco_transf_90 PF05686.7 EMD58777.1 - 5e-11 41.9 3.5 2.9e-06 26.2 2.0 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 90 zf-C2H2 PF00096.21 EMD58778.1 - 0.01 16.1 3.4 0.034 14.4 2.4 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.10 EMD58778.1 - 0.021 14.5 1.8 0.049 13.3 1.2 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 EMD58778.1 - 0.027 14.7 2.8 0.07 13.5 1.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD58778.1 - 0.11 12.8 1.4 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Ras PF00071.17 EMD58781.1 - 5.3e-57 191.7 0.0 6.5e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD58781.1 - 1.3e-20 74.0 0.0 2.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD58781.1 - 2.3e-14 53.0 0.0 4.1e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD58781.1 - 1.5e-07 30.7 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD58781.1 - 3.6e-06 26.5 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMD58781.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMD58781.1 - 0.003 17.5 0.1 0.0059 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD58781.1 - 0.015 15.3 0.0 0.057 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain PTS_2-RNA PF01885.11 EMD58782.1 - 3.5e-66 222.0 0.0 4.3e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Glyco_tranf_2_3 PF13641.1 EMD58783.1 - 3e-21 76.2 0.0 4.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD58783.1 - 5e-10 39.4 0.9 5e-10 39.4 0.6 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMD58783.1 - 5.4e-06 26.1 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD58783.1 - 0.00011 21.5 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Peptidase_U49 PF10463.4 EMD58783.1 - 0.21 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase U49 Herpes_LMP2 PF07415.6 EMD58784.1 - 0.13 10.7 0.3 0.17 10.4 0.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein SnoaL_2 PF12680.2 EMD58785.1 - 0.009 16.4 0.1 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EMD58785.1 - 0.049 13.5 0.2 0.093 12.6 0.2 1.6 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 EMD58785.1 - 0.05 13.8 0.1 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) EII-GUT PF03608.8 EMD58785.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Pro_CA PF00484.14 EMD58786.1 - 1.3e-48 164.8 0.0 1.8e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase OHA PF14418.1 EMD58786.1 - 0.059 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 OST-HTH Associated domain DUF3253 PF11625.3 EMD58787.1 - 3.8e-22 77.9 0.3 4.4e-22 77.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) DUF883 PF05957.8 EMD58789.1 - 0.0048 17.2 14.4 0.19 12.1 4.0 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) NAD_binding_4 PF07993.7 EMD58789.1 - 0.026 13.4 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Phasin PF05597.6 EMD58789.1 - 0.081 12.6 7.9 0.27 10.9 0.8 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2884 PF11101.3 EMD58789.1 - 0.14 11.4 2.2 0.21 10.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Jnk-SapK_ap_N PF09744.4 EMD58789.1 - 0.41 10.6 3.4 0.49 10.3 2.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 OmpH PF03938.9 EMD58789.1 - 2 8.3 13.9 2.6 7.9 9.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.14 EMD58789.1 - 3.1 7.2 7.2 8.2 5.8 1.3 2.1 1 1 1 2 2 2 0 Ribosome recycling factor DUF4449 PF14613.1 EMD58789.1 - 6.2 6.7 8.2 9.2 6.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) AT_hook PF02178.14 EMD58790.1 - 0.019 14.5 2.7 0.061 13.0 1.9 1.9 1 0 0 1 1 1 0 AT hook motif Helicase_Sgs1 PF11408.3 EMD58790.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase DUF4267 PF14087.1 EMD58791.1 - 0.041 13.4 0.3 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) TPP_enzyme_N PF02776.13 EMD58792.1 - 1.8e-31 108.9 0.0 3.7e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD58792.1 - 3.9e-21 75.2 0.0 9.4e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD58792.1 - 2.1e-12 46.8 1.2 4e-11 42.7 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Dioxygenase_C PF00775.16 EMD58793.1 - 1.2e-53 181.1 0.0 1.6e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMD58793.1 - 3.1e-14 52.7 0.1 4.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMD58793.1 - 3.1e-06 27.1 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain MG1 PF11974.3 EMD58793.1 - 0.025 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain YtkA PF13115.1 EMD58793.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 YtkA-like SKIP_SNW PF02731.10 EMD58794.1 - 9.3e-67 223.4 3.1 9.3e-67 223.4 2.2 2.5 2 0 0 2 2 2 1 SKIP/SNW domain FliD_N PF02465.13 EMD58795.1 - 0.23 11.8 3.4 0.16 12.3 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Peptidase_C48 PF02902.14 EMD58796.1 - 1.5e-07 31.2 0.3 2.5e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TAFII28 PF04719.9 EMD58798.1 - 6e-20 70.8 0.0 2.3e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 hTAFII28-like protein conserved region PGA2 PF07543.7 EMD58798.1 - 0.3 10.8 3.0 0.6 9.9 2.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Trypan_PARP PF05887.6 EMD58798.1 - 1.1 9.0 6.2 1.9 8.2 4.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L4 PF00573.17 EMD58799.1 - 8e-44 149.3 0.6 1.1e-43 148.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EMD58799.1 - 1.1e-26 92.4 0.4 1.1e-26 92.4 0.3 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.15 EMD58800.1 - 3e-27 94.7 0.0 5.9e-25 87.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD58800.1 - 0.0058 16.0 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMD58800.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DnaJ PF00226.26 EMD58801.1 - 1.3e-20 72.8 2.4 2.6e-20 71.9 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EMD58802.1 - 1.7e-10 40.6 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD58802.1 - 3.6e-06 26.8 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3535 PF12054.3 EMD58804.1 - 3.4e-138 460.9 1.7 1e-137 459.4 0.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EMD58804.1 - 1.6e-73 247.1 0.0 2.4e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EMD58804.1 - 5.8e-15 53.9 17.0 0.02 14.9 0.2 9.9 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.26 EMD58804.1 - 2e-14 53.1 0.0 5.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 EMD58804.1 - 2e-09 37.6 25.6 0.61 10.6 0.1 10.5 11 0 0 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 EMD58804.1 - 2.5e-08 34.0 18.9 0.0013 18.9 0.3 8.1 7 2 1 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EMD58804.1 - 1.4e-06 28.6 0.1 0.16 12.3 0.0 4.2 3 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMD58804.1 - 9.8e-06 25.0 0.1 0.0012 18.2 0.0 3.5 3 1 1 4 4 4 1 CLASP N terminal UME PF08064.8 EMD58804.1 - 0.15 12.0 1.3 13 5.8 0.1 3.9 3 1 1 4 4 4 0 UME (NUC010) domain Peptidase_A4 PF01828.12 EMD58805.1 - 4.2e-39 133.7 4.2 5.3e-39 133.4 2.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family But2 PF09792.4 EMD58808.1 - 2.6e-14 53.1 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain tRNA-synt_1 PF00133.17 EMD58809.1 - 2.6e-220 732.5 0.1 1.7e-219 729.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMD58809.1 - 4e-26 91.5 0.0 9e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMD58809.1 - 1.1e-17 63.8 0.1 1.8e-06 26.8 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) CHCH PF06747.8 EMD58810.1 - 0.019 14.8 3.4 0.51 10.3 2.4 2.1 1 1 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 EMD58810.1 - 0.025 14.3 3.4 0.037 13.7 1.8 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_1 PF00024.21 EMD58810.1 - 0.029 14.1 0.7 0.032 13.9 0.5 1.1 1 0 0 1 1 1 0 PAN domain NDUF_B7 PF05676.8 EMD58810.1 - 0.07 12.5 1.1 1.8 8.0 0.0 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sfi1 PF08457.5 EMD58811.1 - 4.4e-152 507.4 99.2 1.9e-151 505.3 60.3 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Tannase PF07519.6 EMD58812.1 - 3.9e-104 348.9 0.4 4.8e-104 348.7 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EMD58812.1 - 0.0001 21.5 0.3 0.33 10.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD58812.1 - 0.00019 21.1 0.0 0.001 18.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD58812.1 - 0.00076 19.4 0.0 0.0036 17.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD58812.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1201 PF06716.6 EMD58814.1 - 1.4 8.7 7.4 7.7 6.4 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Amidase PF01425.16 EMD58815.1 - 1.1e-92 311.1 0.8 1.4e-92 310.8 0.5 1.1 1 0 0 1 1 1 1 Amidase DUF3129 PF11327.3 EMD58816.1 - 2.5e-61 206.6 16.0 4.3e-61 205.9 11.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3716 PF12511.3 EMD58816.1 - 0.13 11.9 1.1 0.32 10.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) ADH_N PF08240.7 EMD58817.1 - 3e-28 97.7 1.9 7.8e-28 96.4 1.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD58817.1 - 8.8e-19 67.3 0.3 1.6e-18 66.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EMD58817.1 - 0.015 14.3 0.2 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD58817.1 - 0.067 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EMD58817.1 - 0.093 12.5 2.4 3 7.6 1.0 2.3 1 1 1 2 2 2 0 ThiF family TrkA_N PF02254.13 EMD58817.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AhpC-TSA_2 PF13911.1 EMD58818.1 - 7.4e-23 80.6 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMD58818.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family SET PF00856.23 EMD58819.1 - 5e-12 46.4 0.1 1.1e-11 45.3 0.0 1.6 1 1 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.2 EMD58820.1 - 2.1e-29 103.0 1.6 3.3e-29 102.3 1.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD58820.1 - 2.1e-06 27.5 0.4 5.2e-06 26.2 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 EMD58821.1 - 6.3e-19 68.4 1.0 1e-18 67.8 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD58821.1 - 3e-15 56.6 0.1 6.7e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD58821.1 - 1.3e-06 28.2 0.8 3.3e-06 26.9 0.5 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD58821.1 - 0.02 14.9 0.2 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 EMD58821.1 - 0.04 14.3 1.0 0.12 12.8 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD58821.1 - 0.065 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EMD58821.1 - 0.083 12.5 0.7 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GST_N_2 PF13409.1 EMD58825.1 - 7.4e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMD58825.1 - 2.5e-06 27.6 0.1 6.5e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD58825.1 - 0.00014 21.7 0.1 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD58825.1 - 0.052 14.0 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ldh_1_N PF00056.18 EMD58826.1 - 1.1e-33 116.0 0.1 1.7e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMD58826.1 - 4.6e-30 104.6 0.0 6.2e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 EMD58826.1 - 0.00038 20.8 0.2 0.0012 19.1 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EMD58826.1 - 0.00064 19.1 0.1 0.0049 16.3 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EMD58826.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4154 PF13689.1 EMD58826.1 - 0.051 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Sar8_2 PF03058.9 EMD58826.1 - 0.072 13.4 0.3 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Sar8.2 family TrkA_N PF02254.13 EMD58826.1 - 0.13 12.2 1.4 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 EMD58826.1 - 0.19 11.5 1.3 0.35 10.6 0.2 1.9 2 1 0 2 2 2 0 ThiF family zf-C3HC4_3 PF13920.1 EMD58827.1 - 6.8e-11 41.6 6.4 1e-10 41.1 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD58827.1 - 1.4e-09 37.6 7.4 2.2e-09 37.0 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD58827.1 - 2.2e-09 37.1 6.9 3.7e-09 36.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD58827.1 - 2.5e-08 33.5 7.4 3.9e-08 32.8 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD58827.1 - 5e-07 29.2 7.5 9.3e-07 28.4 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD58827.1 - 0.0068 16.2 5.8 0.039 13.8 4.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMD58827.1 - 0.018 14.5 8.3 0.098 12.2 2.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EMD58827.1 - 0.034 13.8 6.7 0.06 13.0 0.9 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EMD58827.1 - 0.072 12.6 4.4 0.19 11.3 3.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-4CXXC_R1 PF10497.4 EMD58827.1 - 0.2 11.8 2.8 0.32 11.1 1.9 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-rbx1 PF12678.2 EMD58827.1 - 1.6 8.8 6.2 4 7.6 4.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DNA_pol_A PF00476.15 EMD58828.1 - 1.8e-99 332.9 0.0 2.3e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_B_2 PF03175.8 EMD58828.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.15 EMD58828.1 - 0.019 14.4 0.1 0.19 11.1 0.0 2.3 1 1 0 1 1 1 0 3'-5' exonuclease TRAM_LAG1_CLN8 PF03798.11 EMD58830.1 - 5.9e-35 120.6 20.6 5.9e-35 120.6 14.3 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMD58830.1 - 1.1e-20 72.8 0.0 2.4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein ATP-synt_E PF05680.7 EMD58830.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase E chain Atg14 PF10186.4 EMD58831.1 - 5.3e-27 94.5 0.2 7.7e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 EMD58831.1 - 0.043 13.6 6.9 0.074 12.8 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mhr1 PF12829.2 EMD58832.1 - 9.8e-29 99.0 0.0 2.9e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination GFA PF04828.9 EMD58833.1 - 7e-15 54.7 0.1 1.3e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4246 PF14033.1 EMD58834.1 - 9.5e-176 585.2 0.0 1.1e-175 585.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Aldolase_II PF00596.16 EMD58836.1 - 2.3e-46 157.7 0.8 3.2e-46 157.2 0.5 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 EMD58837.1 - 6.3e-38 130.3 57.1 3.5e-36 124.6 39.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EMD58838.1 - 1.8e-34 119.0 0.0 3.7e-34 117.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1993 PF09351.5 EMD58840.1 - 2.8e-45 154.1 0.0 3.2e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MatC_N PF07158.6 EMD58840.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus HATPase_c PF02518.21 EMD58841.1 - 4.3e-23 81.1 0.0 7.3e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD58841.1 - 3.6e-22 78.4 0.2 7.2e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMD58841.1 - 9.7e-09 35.5 0.0 2.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EMD58841.1 - 1.2e-08 34.9 0.0 4.9e-07 29.7 0.0 2.8 2 1 1 3 3 3 1 PAS fold HisKA PF00512.20 EMD58841.1 - 2.9e-07 30.3 3.2 2e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 EMD58841.1 - 1.3e-05 24.8 0.0 4.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EMD58841.1 - 0.00022 20.9 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.2 EMD58841.1 - 0.0055 16.6 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EMD58841.1 - 0.029 14.4 0.0 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 GAF domain Hemerythrin PF01814.18 EMD58842.1 - 1.7e-12 47.6 3.1 2.5e-12 47.0 2.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Occludin_ELL PF07303.8 EMD58842.1 - 0.3 11.8 2.4 1.6 9.4 0.8 2.2 1 1 1 2 2 2 0 Occludin homology domain Piwi PF02171.12 EMD58843.1 - 3e-68 230.0 0.1 4.1e-68 229.5 0.1 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMD58844.1 - 4.3e-05 22.7 0.1 8.5e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Spb1_C PF07780.7 EMD58845.1 - 1.3e-75 253.6 25.5 1.3e-75 253.6 17.7 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EMD58845.1 - 1.2e-53 180.8 13.0 1.2e-53 180.8 9.0 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EMD58845.1 - 2.5e-53 180.7 0.1 5.9e-53 179.5 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rep_fac-A_3 PF08661.6 EMD58847.1 - 9.7e-24 83.3 0.0 1.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 BRCT PF00533.21 EMD58848.1 - 1.4e-06 28.3 0.2 0.00036 20.6 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain STE2 PF02116.10 EMD58849.1 - 9.5e-75 251.2 13.1 1.1e-74 251.0 9.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF4260 PF14079.1 EMD58849.1 - 0.0098 15.7 2.3 0.0098 15.7 1.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4260) DUF4064 PF13273.1 EMD58849.1 - 2.7 8.1 0.0 2.7 8.1 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) HET PF06985.6 EMD58850.1 - 6.4e-20 71.7 9.3 8.2e-17 61.6 6.4 3.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hemerythrin PF01814.18 EMD58851.1 - 3e-09 37.1 0.0 4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LRR_4 PF12799.2 EMD58852.1 - 0.61 9.7 2.6 2.9 7.6 0.1 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_L18p PF00861.17 EMD58853.1 - 3.5e-41 140.1 0.1 3.5e-41 140.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EMD58853.1 - 2.9e-35 120.6 6.3 2.9e-35 120.6 4.4 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Actin PF00022.14 EMD58854.1 - 1e-117 392.9 0.0 1.3e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMD58854.1 - 0.031 12.8 0.0 0.19 10.3 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DUF605 PF04652.11 EMD58855.1 - 1.9 7.8 12.4 1.9 7.7 8.6 1.1 1 0 0 1 1 1 0 Vta1 like Deltaretro_Tax PF05599.6 EMD58857.1 - 0.098 12.9 0.2 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 Deltaretrovirus Tax protein DUF3129 PF11327.3 EMD58859.1 - 3.6e-68 229.0 17.8 5.2e-68 228.5 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Pmp3 PF01679.12 EMD58860.1 - 5.9e-19 67.5 2.3 1.2e-18 66.5 1.6 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2363 PF10155.4 EMD58860.1 - 0.082 12.8 0.1 0.36 10.7 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) CsbD PF05532.7 EMD58861.1 - 9.8e-17 60.3 26.6 2.8e-09 36.5 5.6 3.2 2 1 1 3 3 3 3 CsbD-like IDO PF01231.13 EMD58862.1 - 8e-170 564.8 0.0 9.2e-170 564.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MMR_HSR1_C PF08438.5 EMD58863.1 - 6.7e-33 113.1 0.0 1.5e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EMD58863.1 - 8.8e-18 64.3 0.0 2.1e-17 63.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD58863.1 - 1.2e-08 34.3 0.1 2.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMD58863.1 - 0.00093 18.6 0.1 0.35 10.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain VirB8 PF04335.8 EMD58863.1 - 0.0046 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 VirB8 protein ABC_tran PF00005.22 EMD58863.1 - 0.019 15.2 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 EMD58863.1 - 0.048 13.1 0.1 9 5.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EMD58863.1 - 0.053 13.3 1.3 0.16 11.7 0.2 2.2 3 0 0 3 3 3 0 Dynamin family ArgK PF03308.11 EMD58863.1 - 0.072 11.8 0.6 0.22 10.2 0.0 2.1 3 0 0 3 3 3 0 ArgK protein KTI12 PF08433.5 EMD58863.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EMD58863.1 - 0.15 11.5 0.1 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AIG1 PF04548.11 EMD58863.1 - 0.18 10.8 0.4 0.87 8.6 0.1 2.0 2 0 0 2 2 2 0 AIG1 family Pkinase PF00069.20 EMD58864.1 - 5.9e-56 189.5 0.0 8.3e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD58864.1 - 2e-18 66.4 0.2 4.3e-18 65.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase SPT16 PF08644.6 EMD58864.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) APH PF01636.18 EMD58864.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD58864.1 - 0.15 11.6 0.3 0.31 10.5 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 EMD58865.1 - 6.4e-92 308.1 0.2 7.8e-92 307.8 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 EMD58865.1 - 0.12 11.8 2.9 0.17 11.3 0.2 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Tubulin PF00091.20 EMD58866.1 - 1.1e-72 244.3 0.0 1.6e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD58866.1 - 4.2e-46 156.0 1.2 6.7e-46 155.4 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain GDPD PF03009.12 EMD58866.1 - 3.2e-33 115.2 0.0 8.8e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.4 EMD58866.1 - 8.1e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.1 EMD58866.1 - 0.0013 18.9 0.2 0.0047 17.0 0.1 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Tubulin_3 PF14881.1 EMD58866.1 - 0.03 13.8 0.0 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Coatomer_E PF04733.9 EMD58867.1 - 6.1e-58 196.3 7.6 7.5e-58 196.0 5.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 EMD58867.1 - 5.6e-06 25.8 5.2 0.021 14.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD58867.1 - 9.9e-06 25.7 10.5 0.026 15.1 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58867.1 - 5.7e-05 22.6 5.9 0.0006 19.4 0.0 4.0 2 2 3 5 5 5 1 TPR repeat TPR_12 PF13424.1 EMD58867.1 - 6.1e-05 22.8 7.4 0.21 11.5 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD58867.1 - 0.00047 20.7 10.3 0.22 12.2 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD58867.1 - 0.00085 19.6 14.6 0.0082 16.4 1.4 3.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58867.1 - 0.0013 18.2 0.2 0.13 11.8 0.0 3.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD58867.1 - 0.0031 17.1 0.0 0.34 10.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD58867.1 - 0.0075 16.3 1.8 1.7 8.8 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMD58867.1 - 0.014 15.7 8.5 0.043 14.2 0.5 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1110 PF06533.7 EMD58867.1 - 0.11 12.3 9.4 0.036 13.8 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) DUF3366 PF11846.3 EMD58867.1 - 0.39 10.5 4.0 0.12 12.2 0.2 2.0 2 2 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_6 PF13174.1 EMD58867.1 - 0.42 11.1 2.3 55 4.5 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Methyltransf_25 PF13649.1 EMD58868.1 - 4.8e-10 39.6 0.1 8.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD58868.1 - 6.4e-05 23.3 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD58868.1 - 9.7e-05 22.0 0.4 0.0002 20.9 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD58868.1 - 0.044 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.12 EMD58869.1 - 1.6e-95 318.7 0.0 2.2e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EMD58869.1 - 0.00077 20.0 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD58869.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD58869.1 - 0.012 16.1 0.2 0.083 13.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMD58869.1 - 0.11 12.2 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NAD_kinase PF01513.16 EMD58870.1 - 1.3e-68 230.8 0.0 1.7e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase PEP_mutase PF13714.1 EMD58871.1 - 6.9e-49 166.2 0.5 7.9e-49 166.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMD58871.1 - 4.7e-22 77.8 0.0 6.8e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EMD58871.1 - 0.006 15.7 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Zn_clus PF00172.13 EMD58872.1 - 0.00015 21.6 8.3 0.00032 20.5 0.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EMD58872.1 - 0.00015 20.1 41.3 0.00015 20.1 28.6 1.5 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 EMD58872.1 - 0.052 11.2 15.1 0.074 10.7 10.5 1.1 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 EMD58872.1 - 0.12 12.7 23.6 0.18 12.0 16.4 1.2 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.1 EMD58872.1 - 0.14 11.2 19.1 0.3 10.1 13.2 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.10 EMD58872.1 - 0.17 10.4 14.2 0.27 9.8 9.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 EMD58872.1 - 0.39 9.6 6.4 0.69 8.8 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 EMD58872.1 - 1 8.1 17.1 1.6 7.5 11.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 EMD58872.1 - 1.4 6.5 20.2 2 5.9 14.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.3 EMD58872.1 - 2.1 6.8 15.4 3.1 6.3 10.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pal1 PF08316.6 EMD58872.1 - 3.3 8.1 11.4 7.4 7.0 7.9 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein PIH1 PF08190.7 EMD58872.1 - 7.7 5.8 27.4 14 4.9 19.0 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 eIF-3_zeta PF05091.7 EMD58872.1 - 8 4.9 26.9 12 4.3 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YscO PF07321.7 EMD58873.1 - 0.00016 21.4 15.3 0.00016 21.4 10.6 3.9 3 1 1 4 4 4 2 Type III secretion protein YscO IncA PF04156.9 EMD58873.1 - 0.0011 18.6 6.7 0.0011 18.6 4.7 3.7 1 1 2 3 3 3 2 IncA protein BLOC1_2 PF10046.4 EMD58873.1 - 0.0011 19.0 1.8 0.0011 19.0 1.3 5.0 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CesA PF11439.3 EMD58873.1 - 0.0023 17.7 1.3 0.0023 17.7 0.9 2.7 2 1 0 2 2 2 1 Type III secretion system filament chaperone CesA DUF869 PF05911.6 EMD58873.1 - 0.0083 14.4 47.7 0.025 12.8 17.5 2.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) bZIP_2 PF07716.10 EMD58873.1 - 0.24 11.2 19.4 0.57 10.0 0.6 5.3 3 1 2 5 5 5 0 Basic region leucine zipper bZIP_1 PF00170.16 EMD58873.1 - 4.1 7.4 21.7 1.3 9.0 0.7 5.3 3 1 2 5 5 5 0 bZIP transcription factor HALZ PF02183.13 EMD58873.1 - 9.3 6.0 24.9 6.1 6.6 0.6 5.9 5 1 1 6 6 6 0 Homeobox associated leucine zipper HTH_Tnp_Tc3_2 PF01498.13 EMD58874.1 - 1.9e-17 63.1 0.2 3.3e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EMD58874.1 - 5.9e-08 32.8 0.0 8.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EMD58874.1 - 5.8e-07 28.9 0.0 4.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EMD58874.1 - 7e-05 23.5 1.4 7.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EMD58874.1 - 8.9e-05 21.5 1.3 0.13 11.4 0.0 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EMD58874.1 - 0.00034 20.5 0.1 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 HTH-like domain HTH_33 PF13592.1 EMD58874.1 - 0.0048 16.4 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EMD58874.1 - 0.054 12.2 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Sigma70_r4_2 PF08281.7 EMD58874.1 - 0.069 12.6 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 G-alpha PF00503.15 EMD58876.1 - 5e-116 387.5 0.5 5.8e-116 387.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMD58876.1 - 8.3e-14 51.2 0.7 5.6e-09 35.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD58876.1 - 5.5e-05 22.4 2.8 0.0018 17.4 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF2985 PF11204.3 EMD58876.1 - 0.027 14.1 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) AAA_15 PF13175.1 EMD58876.1 - 0.035 13.1 0.7 0.099 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EMD58876.1 - 0.041 13.8 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EMD58876.1 - 0.052 13.0 0.2 0.18 11.3 0.1 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EMD58876.1 - 0.055 13.9 0.0 8.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EMD58876.1 - 0.072 12.5 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1713 PF08213.6 EMD58877.1 - 3.3e-13 48.9 21.2 7.3e-13 47.8 14.7 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Med15 PF09606.5 EMD58878.1 - 8.6 4.4 25.9 12 3.9 18.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hexapep PF00132.19 EMD58880.1 - 2e-14 52.3 15.1 0.00045 19.5 0.7 5.2 4 1 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD58880.1 - 6.8e-08 31.9 9.7 2.2e-07 30.3 0.9 4.0 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fungal_trans PF04082.13 EMD58881.1 - 1e-22 80.3 0.0 2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMD58881.1 - 1.7e-08 34.2 15.1 0.00033 20.8 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD58881.1 - 6.4e-06 26.2 7.3 6.4e-06 26.2 5.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD58881.1 - 0.00018 21.6 15.9 0.068 13.5 2.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DLIC PF05783.6 EMD58881.1 - 0.17 10.5 1.9 0.45 9.1 1.3 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Maf1 PF09174.5 EMD58883.1 - 3.1e-49 167.2 0.0 4.2e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 EMD58884.1 - 5.4e-53 178.5 1.8 6.4e-53 178.2 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 EMD58885.1 - 8.3e-16 57.6 0.0 1.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3484 PF11983.3 EMD58886.1 - 0.095 13.5 0.5 0.095 13.5 0.3 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3484) Glyco_hydro_72 PF03198.9 EMD58889.1 - 6.3e-130 432.7 3.8 7.6e-130 432.4 2.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMD58889.1 - 7.1e-05 22.1 0.2 0.14 11.3 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EMD58889.1 - 0.00032 19.7 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Syntaxin PF00804.20 EMD58890.1 - 1.4e-09 38.0 5.4 1.4e-09 38.0 3.7 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EMD58890.1 - 1.6e-07 30.8 6.4 1.6e-07 30.8 4.5 2.4 2 0 0 2 2 2 1 SNARE domain DUF2721 PF11026.3 EMD58890.1 - 0.0076 15.8 1.6 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) DUF912 PF06024.7 EMD58890.1 - 0.012 15.6 0.2 0.012 15.6 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 EMD58890.1 - 0.014 15.2 0.5 0.09 12.6 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TMEM156 PF15106.1 EMD58890.1 - 0.048 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DUF2077 PF09850.4 EMD58890.1 - 0.079 12.3 2.1 0.26 10.6 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4094 PF13334.1 EMD58890.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) Syntaxin_2 PF14523.1 EMD58890.1 - 0.29 11.1 12.2 0.038 14.0 3.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Synaptobrevin PF00957.16 EMD58890.1 - 0.72 9.5 5.0 0.21 11.2 1.2 1.8 2 0 0 2 2 2 0 Synaptobrevin SlyX PF04102.7 EMD58890.1 - 9.5 6.6 14.1 0.74 10.2 4.4 2.8 2 1 2 4 4 4 0 SlyX Nup188 PF10487.4 EMD58891.1 - 5.9e-44 150.2 0.1 4e-41 140.9 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EMD58892.1 - 1.7e-97 325.4 0.1 1.7e-95 318.9 0.0 2.2 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase GATase PF00117.23 EMD58892.1 - 5.5e-52 176.0 0.1 1.4e-51 174.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 EMD58892.1 - 9.9e-51 172.1 1.2 1.5e-47 161.7 0.5 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EMD58892.1 - 2.3e-07 30.4 0.0 5.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 NanE PF04131.9 EMD58892.1 - 4.6e-05 22.4 0.3 0.013 14.5 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.14 EMD58892.1 - 0.0028 17.1 0.9 0.033 13.6 0.1 2.8 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain BRCT PF00533.21 EMD58893.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD58893.1 - 3.2e-06 26.8 0.4 8.3e-06 25.5 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain HhH-GPD PF00730.20 EMD58895.1 - 3.6e-19 69.0 0.0 8.4e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMD58895.1 - 3.5e-07 29.5 0.0 9.5e-07 28.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF221 PF02714.10 EMD58896.1 - 2.4e-107 358.5 23.2 4.3e-107 357.7 16.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD58896.1 - 1.8e-19 69.8 2.1 1.8e-19 69.8 1.5 4.2 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMD58896.1 - 1.5e-14 53.5 2.3 2e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EMD58896.1 - 1.6e-11 44.5 1.6 3.5e-05 24.2 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) TFIIA PF03153.8 EMD58897.1 - 0.015 15.1 13.1 0.025 14.5 9.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 EMD58897.1 - 0.14 12.5 21.0 0.22 11.8 14.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3987 PF13148.1 EMD58897.1 - 0.17 10.4 9.6 0.013 14.0 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Hamartin PF04388.7 EMD58897.1 - 4.4 5.8 11.7 6 5.4 8.1 1.1 1 0 0 1 1 1 0 Hamartin protein FTA4 PF13093.1 EMD58899.1 - 6.5e-58 195.6 6.1 8.3e-58 195.3 4.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PCEMA1 PF07418.6 EMD58899.1 - 0.015 14.6 3.2 0.021 14.1 2.2 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 p450 PF00067.17 EMD58900.1 - 1.7e-07 30.1 0.2 5.5e-07 28.4 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.17 EMD58901.1 - 7.6e-40 136.5 0.0 9.2e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 EMD58901.1 - 0.0094 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EMD58901.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) PE-PPE PF08237.6 EMD58901.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.3 EMD58901.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Inhibitor_I53 PF11714.3 EMD58901.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Thrombin inhibitor Madanin VirJ PF06057.6 EMD58901.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.17 EMD58902.1 - 1.1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EMD58902.1 - 6.9e-05 22.5 0.0 8.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD58902.1 - 0.00025 20.8 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EMD58902.1 - 0.00043 19.7 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EMD58902.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EMD58902.1 - 0.0067 16.0 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EMD58902.1 - 0.036 13.9 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EMD58902.1 - 0.055 13.6 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 EMD58902.1 - 0.074 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 EMD58903.1 - 2.7e-54 183.7 0.0 4.4e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EMD58903.1 - 3.8e-06 26.7 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD58903.1 - 8.8e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EMD58903.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EMD58903.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNase_T PF00929.19 EMD58904.1 - 3.4e-14 53.4 0.0 9e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Pcc1 PF09341.5 EMD58905.1 - 1.5e-23 82.5 0.2 2e-23 82.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 TPR_12 PF13424.1 EMD58907.1 - 5.7e-15 55.0 0.0 1.1e-08 34.9 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMD58907.1 - 1.1e-14 53.8 0.5 1.9e-05 24.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD58907.1 - 7.9e-08 32.2 0.0 0.0074 16.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD58907.1 - 3.8e-07 29.4 0.0 0.0065 16.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD58907.1 - 2.1e-06 27.2 0.0 0.08 12.6 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EMD58907.1 - 1.1e-05 24.9 0.0 0.052 13.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD58907.1 - 0.00013 22.2 0.0 0.34 11.2 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Paf67 PF10255.4 EMD58907.1 - 0.00017 20.6 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.9 EMD58907.1 - 0.00063 19.9 0.0 0.21 12.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD58907.1 - 0.018 15.1 0.0 0.54 10.4 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMD58907.1 - 0.034 14.8 0.0 0.38 11.4 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD58907.1 - 0.041 13.4 0.0 2 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ODAM PF15424.1 EMD58907.1 - 0.077 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family F-box PF00646.28 EMD58908.1 - 0.041 13.5 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.1 EMD58908.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.3 3 0 0 3 3 3 0 F-box-like domain WSC PF01822.14 EMD58910.1 - 2.4e-10 40.2 5.9 2.4e-10 40.2 4.1 2.9 3 0 0 3 3 3 1 WSC domain DUF342 PF03961.8 EMD58910.1 - 0.098 11.0 4.6 0.16 10.3 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 EMD58910.1 - 1.7 9.4 8.8 1.5 9.6 4.4 1.9 1 1 1 2 2 2 0 Occludin homology domain IncA PF04156.9 EMD58910.1 - 8.1 5.9 15.0 12 5.4 10.4 1.1 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 EMD58910.1 - 9.7 6.0 17.7 17 5.2 7.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding WSC PF01822.14 EMD58911.1 - 4e-15 55.5 12.5 4.5e-15 55.3 8.7 1.0 1 0 0 1 1 1 1 WSC domain zf-DHHC PF01529.15 EMD58913.1 - 2.8e-44 150.5 4.1 6.1e-44 149.4 2.8 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3955 PF13127.1 EMD58913.1 - 0.0089 15.5 3.1 0.02 14.4 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) ABC2_membrane_2 PF12679.2 EMD58913.1 - 0.038 12.8 0.2 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DZR PF12773.2 EMD58913.1 - 0.069 12.9 7.1 0.14 11.9 4.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Yip1 PF04893.12 EMD58913.1 - 2.2 7.7 14.7 0.054 12.9 1.3 2.1 2 0 0 2 2 2 0 Yip1 domain DUF3553 PF12073.3 EMD58914.1 - 0.13 11.5 0.1 0.31 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) HAD_2 PF13419.1 EMD58916.1 - 8.2e-11 42.4 0.0 1.8e-06 28.3 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD58916.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like FliM PF02154.10 EMD58917.1 - 0.033 13.8 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Methyltransf_16 PF10294.4 EMD58918.1 - 5.6e-17 61.7 0.0 7.4e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMD58918.1 - 0.00047 20.7 0.0 0.00081 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EMD58918.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NodS PF05401.6 EMD58918.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Copper-fist PF00649.13 EMD58919.1 - 4.6e-15 54.5 2.7 4.6e-15 54.5 1.9 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain SUN PF03856.8 EMD58920.1 - 4e-75 252.3 14.1 5.4e-75 251.8 9.8 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 EMD58920.1 - 1 8.7 6.4 1.5 8.1 4.5 1.2 1 0 0 1 1 1 0 Vta1 like FCH PF00611.18 EMD58921.1 - 2.3e-24 85.3 0.1 2.3e-24 85.3 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMD58921.1 - 4.5e-17 61.3 0.5 9e-11 41.1 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain C1_1 PF00130.17 EMD58921.1 - 5.6e-14 51.5 5.4 8.8e-14 50.9 3.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EMD58921.1 - 7.3e-14 50.8 0.2 2.4e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 EMD58921.1 - 0.015 15.4 0.5 0.12 12.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 EMD58921.1 - 0.31 11.2 8.1 0.57 10.3 5.6 1.4 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 EMD58922.1 - 3.6e-32 111.1 0.0 1.8e-31 108.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD58922.1 - 4.7e-24 84.0 0.1 1.1e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMD58922.1 - 0.13 12.4 0.7 0.61 10.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain Anp1 PF03452.9 EMD58924.1 - 4e-110 367.2 0.0 5.1e-110 366.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Myelin_MBP PF01669.12 EMD58924.1 - 0.024 14.8 0.5 0.048 13.9 0.4 1.6 1 1 0 1 1 1 0 Myelin basic protein Glycos_transf_2 PF00535.21 EMD58924.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 YEATS PF03366.11 EMD58927.1 - 2e-22 78.7 0.1 3.6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EMD58928.1 - 6.6e-50 168.2 1.5 1e-49 167.5 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EMD58928.1 - 5.3e-05 22.9 0.3 0.00041 20.0 0.2 2.0 1 1 0 1 1 1 1 WH1 domain Glyco_transf_15 PF01793.11 EMD58930.1 - 4e-132 440.1 2.1 5.2e-132 439.8 1.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.1 EMD58931.1 - 4.3e-25 88.7 22.1 5.1e-25 88.5 15.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF1639 PF07797.9 EMD58931.1 - 0.044 13.1 2.6 0.11 11.9 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Herpes_DNAp_acc PF04929.7 EMD58931.1 - 0.89 8.4 8.7 1 8.2 6.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Cut8_N PF14482.1 EMD58931.1 - 1.8 8.6 12.9 0.47 10.4 2.8 3.1 1 1 1 2 2 2 0 Cut8 proteasome-binding domain Cauli_AT PF03233.8 EMD58932.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Aphid transmission protein CAF-1_p60_C PF15512.1 EMD58932.1 - 1.3 9.4 11.4 0.31 11.4 2.7 2.1 1 1 1 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal APC_CDC26 PF10471.4 EMD58932.1 - 1.3 9.8 8.7 6.1 7.6 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pol_alpha_B_N PF08418.5 EMD58932.1 - 6.1 6.2 10.9 32 3.9 7.5 1.9 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF912 PF06024.7 EMD58935.1 - 1.9 8.5 5.9 2.5 8.2 3.4 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NB PF04159.8 EMD58936.1 - 0.019 14.7 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 NB glycoprotein IncA PF04156.9 EMD58936.1 - 1.8 8.1 6.5 1.7 8.2 0.1 3.0 3 0 0 3 3 3 0 IncA protein WD40 PF00400.27 EMD58937.1 - 4.5e-93 302.1 15.7 3.6e-14 51.9 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMD58937.1 - 7.2e-14 50.8 10.6 0.094 10.8 0.0 6.3 1 1 5 6 6 6 6 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 EMD58937.1 - 6.2e-10 38.2 0.0 11 5.4 0.0 7.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature eIF2A PF08662.6 EMD58937.1 - 6.2e-09 35.8 0.0 0.007 16.1 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 EMD58937.1 - 7.5e-08 32.2 0.2 2.6e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EMD58937.1 - 6.3e-06 26.3 0.1 6.3e-06 26.3 0.1 3.3 3 1 0 3 3 2 1 AAA ATPase domain TruB_C PF09142.6 EMD58937.1 - 1.8e-05 24.2 6.1 31 4.3 0.0 6.4 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal DUF1513 PF07433.6 EMD58937.1 - 0.00011 21.2 4.9 0.21 10.4 0.2 4.1 1 1 3 4 4 4 2 Protein of unknown function (DUF1513) AAA PF00004.24 EMD58937.1 - 0.00016 21.8 0.0 0.00057 20.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IKI3 PF04762.7 EMD58937.1 - 0.00016 19.6 0.1 2.7 5.6 0.0 3.6 1 1 1 3 3 3 2 IKI3 family NB-ARC PF00931.17 EMD58937.1 - 0.00021 20.2 0.0 0.00045 19.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EMD58937.1 - 0.00086 19.4 0.1 0.0048 17.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain DUF1258 PF06869.7 EMD58937.1 - 0.0066 15.5 1.2 18 4.2 0.0 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) APS_kinase PF01583.15 EMD58937.1 - 0.014 15.0 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EMD58937.1 - 0.02 14.6 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PIF1 PF05970.9 EMD58937.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_17 PF13207.1 EMD58937.1 - 0.054 14.3 0.1 0.27 12.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD58937.1 - 0.098 12.8 0.1 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.11 EMD58937.1 - 0.15 11.3 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EMD58937.1 - 0.18 11.3 2.0 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain SurE PF01975.12 EMD58937.1 - 1.1 8.5 5.9 8.2 5.6 0.1 4.1 1 1 4 5 5 5 0 Survival protein SurE AAA_11 PF13086.1 EMD58941.1 - 3.3e-60 203.6 0.5 1e-59 201.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMD58941.1 - 4.5e-57 192.6 0.0 7.3e-56 188.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD58941.1 - 5.2e-13 48.5 0.1 6.6e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMD58941.1 - 1.5e-11 44.2 0.1 8.1e-10 38.5 0.1 3.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMD58941.1 - 5.6e-08 32.8 0.0 2e-07 31.0 0.0 1.9 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EMD58941.1 - 1.4e-07 31.1 0.1 3.2e-05 23.4 0.1 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EMD58941.1 - 7e-07 28.5 1.2 4.9e-06 25.7 0.9 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EMD58941.1 - 2.4e-05 23.9 0.0 0.9 9.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.1 EMD58941.1 - 4.3e-05 23.1 0.1 2 7.7 0.1 3.3 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EMD58941.1 - 0.00016 21.8 0.2 0.0026 17.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EMD58941.1 - 0.00019 21.5 0.1 1 9.5 0.0 3.4 2 1 0 3 3 3 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 EMD58941.1 - 0.00038 19.9 0.2 0.0022 17.5 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EMD58941.1 - 0.00057 19.4 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family PhoH PF02562.11 EMD58941.1 - 0.00075 18.7 0.0 0.036 13.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 EMD58941.1 - 0.00092 18.8 0.0 0.052 13.1 0.0 2.8 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 EMD58941.1 - 0.0015 18.5 0.2 0.0053 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EMD58941.1 - 0.0026 16.7 0.0 0.0077 15.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EMD58941.1 - 0.0045 16.4 0.0 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EMD58941.1 - 0.0068 16.1 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 1 1 Flavivirus DEAD domain 4HB_MCP_1 PF12729.2 EMD58941.1 - 0.0072 15.6 0.9 0.02 14.2 0.6 1.7 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction AAA_5 PF07728.9 EMD58941.1 - 0.018 14.7 0.0 0.094 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EMD58941.1 - 0.02 15.0 0.1 0.058 13.6 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMD58941.1 - 0.033 13.6 0.0 0.093 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.7 EMD58941.1 - 0.04 13.3 0.0 0.12 11.8 0.0 1.8 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EMD58941.1 - 0.08 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMD58941.1 - 0.46 11.3 2.4 0.77 10.5 0.5 2.4 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EMD58941.1 - 1.7 8.9 7.7 3.4 7.9 0.0 2.8 2 1 0 3 3 3 0 AAA domain COesterase PF00135.23 EMD58943.1 - 2.5e-95 320.2 0.0 3.3e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD58943.1 - 0.0001 21.9 0.0 0.00072 19.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 EMD58945.1 - 3.7e-132 441.1 62.3 7.8e-130 433.4 21.8 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EMD58945.1 - 2.9e-33 115.0 74.5 5.3e-23 81.2 17.6 4.2 2 2 2 4 4 4 4 Major Facilitator Superfamily adh_short PF00106.20 EMD58946.1 - 2.6e-32 112.0 8.0 3.5e-32 111.6 5.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD58946.1 - 7.2e-26 91.4 1.2 8.7e-26 91.1 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD58946.1 - 6.6e-16 58.4 5.0 9.7e-16 57.9 3.4 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EMD58946.1 - 0.025 13.6 0.9 0.083 11.9 0.0 2.1 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EMD58946.1 - 0.07 12.7 1.5 0.14 11.8 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nop16 PF09420.5 EMD58947.1 - 1.3e-49 168.4 8.8 1.5e-49 168.2 6.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 EMD58948.1 - 3.1e-58 197.2 5.5 7.6e-58 195.9 3.8 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.20 EMD58950.1 - 6e-16 58.3 0.0 7.4e-12 44.9 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain IBR PF01485.16 EMD58950.1 - 7.7e-09 35.3 6.0 1.6e-08 34.2 4.1 1.5 1 0 0 1 1 1 1 IBR domain Pkinase_Tyr PF07714.12 EMD58950.1 - 1.3e-06 27.6 0.0 3.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD58950.1 - 0.011 14.7 0.0 0.044 12.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Ribosomal_L39 PF00832.15 EMD58950.1 - 0.11 11.9 1.8 0.23 10.9 1.3 1.6 1 0 0 1 1 1 0 Ribosomal L39 protein zf-RING_4 PF14570.1 EMD58950.1 - 0.21 11.1 6.3 0.42 10.2 4.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.20 EMD58951.1 - 1.6e-14 54.1 2.7 1.7e-14 54.0 0.1 2.3 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EMD58951.1 - 1e-07 31.8 0.2 2.3e-07 30.6 0.1 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMD58951.1 - 1.1e-05 25.3 0.0 8.2e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMD58951.1 - 0.00017 20.5 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DEK_C PF08766.6 EMD58951.1 - 0.022 14.5 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 DEK C terminal domain QRPTase_C PF01729.14 EMD58951.1 - 0.11 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain FAD_binding_3 PF01494.14 EMD58952.1 - 4.2e-13 49.0 2.7 1.5e-09 37.4 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD58952.1 - 1.6e-05 24.0 0.2 0.0019 17.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD58952.1 - 0.00032 19.6 0.0 0.00061 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD58952.1 - 0.0014 18.5 0.6 0.0036 17.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD58952.1 - 0.0017 18.3 0.1 0.0048 16.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD58952.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD58952.1 - 0.016 15.6 0.6 3.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD58952.1 - 0.074 11.5 0.1 0.84 8.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EMD58952.1 - 0.14 10.9 0.1 0.27 10.0 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Sugar_tr PF00083.19 EMD58953.1 - 2.4e-79 267.0 23.5 2.8e-79 266.8 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD58953.1 - 6.7e-20 71.1 30.7 2.1e-19 69.4 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EMD58955.1 - 7.6e-63 212.6 0.0 9.6e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 EMD58956.1 - 9.9e-101 337.5 0.0 1.3e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 EMD58957.1 - 5.6e-92 308.2 0.0 7.2e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD58957.1 - 6.8e-15 55.7 0.1 2.1e-14 54.2 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PqiA PF04403.8 EMD58957.1 - 0.31 10.6 1.8 0.63 9.6 1.3 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A NDUF_B7 PF05676.8 EMD58958.1 - 4.5e-33 112.4 4.2 5.4e-33 112.2 2.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EMD58958.1 - 0.0097 15.6 1.6 0.014 15.1 1.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.2 EMD58959.1 - 2.1e-13 50.4 0.0 2.5e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD58959.1 - 4e-12 45.2 0.5 0.00038 20.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMD58959.1 - 3.9e-11 42.8 1.5 3e-05 24.1 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD58959.1 - 8.7e-11 42.0 0.2 2.8e-06 27.6 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD58959.1 - 1.8e-06 27.6 0.4 0.77 10.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EMD58959.1 - 3.5e-05 23.3 0.7 0.00022 20.8 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain MbeD_MobD PF04899.7 EMD58959.1 - 0.003 17.4 1.9 0.01 15.7 0.7 2.4 2 0 0 2 2 2 1 MbeD/MobD like Cupin_4 PF08007.7 EMD58959.1 - 0.021 14.1 1.4 0.062 12.5 0.9 1.8 1 0 0 1 1 1 0 Cupin superfamily protein DUF4286 PF14114.1 EMD58959.1 - 0.19 12.0 1.2 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) TFIIA PF03153.8 EMD58959.1 - 3.4 7.4 8.9 5.2 6.8 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EamA PF00892.15 EMD58960.1 - 2.3e-08 34.1 25.5 3.7e-07 30.2 1.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMD58960.1 - 1.4e-06 28.4 1.2 1.4e-06 28.4 0.8 3.7 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EMD58960.1 - 0.017 13.9 0.2 0.056 12.2 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EMD58960.1 - 0.063 12.9 13.7 0.17 11.5 1.5 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family PTPA PF03095.10 EMD58961.1 - 7.3e-108 360.2 0.0 8.5e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GSHPx PF00255.14 EMD58962.1 - 1.1e-37 127.7 0.1 1.4e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMD58962.1 - 0.0013 18.4 0.1 0.0021 17.7 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 EMD58962.1 - 0.0059 16.7 0.1 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 EMD58962.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.6 1 1 0 1 1 1 0 Redoxin zf-C2H2 PF00096.21 EMD58964.1 - 4.7 7.7 10.7 1.8 9.0 1.9 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Planc_extracel PF07595.7 EMD58966.1 - 7.7 6.3 7.6 0.41 10.3 1.0 2.2 3 0 0 3 3 3 0 Planctomycete extracellular DUF1771 PF08590.5 EMD58967.1 - 6e-23 80.6 10.3 6e-23 80.6 7.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMD58967.1 - 9.8e-17 60.9 0.4 2.6e-16 59.5 0.3 1.8 1 0 0 1 1 1 1 Smr domain Use1 PF09753.4 EMD58967.1 - 1.4e-11 44.2 0.6 1.4e-11 44.2 0.4 2.1 2 0 0 2 2 2 1 Membrane fusion protein Use1 Chordopox_A30L PF06015.7 EMD58967.1 - 0.022 14.3 0.8 0.058 13.0 0.1 2.0 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Synaptobrevin PF00957.16 EMD58967.1 - 0.049 13.2 0.0 0.049 13.2 0.0 3.4 4 0 0 4 4 4 0 Synaptobrevin DUF2730 PF10805.3 EMD58967.1 - 0.054 13.2 0.7 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PI-PLC-X PF00388.14 EMD58969.1 - 1.2e-61 206.3 0.0 2.2e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMD58969.1 - 1.4e-38 131.4 0.0 2.7e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMD58969.1 - 0.00033 20.5 0.0 0.00098 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 EMD58969.1 - 0.0006 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Hydrolase_6 PF13344.1 EMD58972.1 - 5.9e-23 80.6 0.0 1.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD58972.1 - 2.2e-11 43.3 0.0 1.5e-10 40.5 0.0 2.5 3 1 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EMD58972.1 - 0.015 15.5 0.0 4.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD58972.1 - 0.024 15.0 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.9 EMD58974.1 - 5e-23 81.1 4.7 6.8e-22 77.4 0.9 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMD58974.1 - 1e-21 76.8 0.5 3.5e-20 71.8 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EMD58974.1 - 0.00086 19.2 0.0 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Pro_isomerase PF00160.16 EMD58975.1 - 2.2e-43 148.1 0.0 5.3e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EMD58975.1 - 3.9e-07 29.5 2.2 7.1e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EMD58975.1 - 2.9e-05 23.9 0.1 0.00016 21.6 0.0 2.1 1 1 1 2 2 2 1 U-box domain ADH_N PF08240.7 EMD58976.1 - 1.4e-27 95.6 4.0 1.4e-27 95.6 2.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD58976.1 - 1.1e-15 57.3 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD58976.1 - 0.0021 18.9 0.0 0.0046 17.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EMD58976.1 - 0.0066 16.0 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EMD58976.1 - 0.044 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF605 PF04652.11 EMD58977.1 - 0.099 12.0 11.7 0.11 11.8 8.1 1.1 1 0 0 1 1 1 0 Vta1 like DHHW PF14286.1 EMD58977.1 - 0.13 11.5 2.5 0.18 11.1 1.7 1.1 1 0 0 1 1 1 0 DHHW protein DUF2217 PF10265.4 EMD58977.1 - 3.8 6.1 11.0 4.8 5.8 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PAP1 PF08601.5 EMD58977.1 - 3.8 7.1 22.0 5.2 6.6 15.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4614 PF15391.1 EMD58977.1 - 5.1 6.8 21.0 7.3 6.3 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 EMD58977.1 - 5.3 6.4 18.9 6.8 6.0 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 EMD58977.1 - 5.8 5.0 19.1 7.5 4.6 13.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 EMD58977.1 - 5.9 6.0 9.1 7.5 5.6 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Musclin PF11037.3 EMD58977.1 - 6.9 6.2 7.4 0.46 10.1 0.1 2.5 3 1 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle ORC6 PF05460.8 EMD58977.1 - 9.3 5.2 15.1 12 4.8 10.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_5 PF12695.2 EMD58978.1 - 9.6e-05 22.1 0.3 0.00055 19.7 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD58978.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EMD58978.1 - 0.00026 20.9 0.3 0.00048 20.0 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMD58978.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EMD58978.1 - 0.041 12.8 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EMD58978.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) 6PF2K PF01591.13 EMD58981.1 - 2.2e-61 206.7 0.0 3.2e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMD58981.1 - 4.1e-24 85.4 0.9 7.4e-24 84.6 0.6 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EMD58981.1 - 0.00022 22.0 0.2 0.0019 18.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD58981.1 - 0.00031 20.6 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMD58981.1 - 0.0027 16.9 0.0 0.0085 15.3 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Porin_3 PF01459.17 EMD58982.1 - 3e-75 253.0 0.0 3.5e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tom22 PF04281.8 EMD58983.1 - 1.4e-46 157.4 2.0 1.6e-46 157.2 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Amidohydro_2 PF04909.9 EMD58984.1 - 1.4e-41 142.9 0.5 1.6e-41 142.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase NACHT PF05729.7 EMD58985.1 - 1.2e-08 34.7 0.1 3.7e-08 33.2 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMD58985.1 - 0.0035 17.4 0.0 0.0092 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD58985.1 - 0.0041 17.1 1.1 0.045 13.7 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMD58985.1 - 0.0046 17.7 0.4 0.12 13.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EMD58985.1 - 0.0073 16.6 0.0 0.047 13.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMD58985.1 - 0.014 15.6 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EMD58985.1 - 0.018 14.9 0.1 0.098 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMD58985.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EMD58985.1 - 0.042 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EMD58985.1 - 0.073 12.7 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EMD58985.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD58985.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMD58985.1 - 0.1 12.5 0.0 1 9.3 0.0 2.5 2 1 1 3 3 3 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EMD58985.1 - 0.13 11.6 0.2 0.51 9.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.4 EMD58985.1 - 0.14 11.0 0.0 6 5.7 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 EMD58985.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 EMD58985.1 - 0.16 11.9 1.8 14 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain GCS PF03074.11 EMD58986.1 - 2.5e-155 517.0 0.0 3.3e-155 516.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 EMD58987.1 - 1e-14 53.5 5.2 1.8e-14 52.7 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EMD58987.1 - 0.26 11.3 1.9 0.56 10.2 1.3 1.5 1 0 0 1 1 1 0 zinc-finger DUF2014 PF09427.5 EMD58991.1 - 1.8e-105 351.7 4.0 1.8e-105 351.7 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2014) HLH PF00010.21 EMD58991.1 - 9.6e-18 63.6 0.1 2.5e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Kdo PF06293.9 EMD58993.1 - 2.3e-08 33.3 0.1 1.2e-06 27.7 0.0 2.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD58993.1 - 6.9e-07 29.2 0.7 0.12 12.1 0.3 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EMD58993.1 - 7.9e-06 25.2 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EMD58993.1 - 4e-05 23.0 0.0 8.2e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EMD58993.1 - 0.0025 16.9 0.0 0.0043 16.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EMD58993.1 - 0.011 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SCHIP-1 PF10148.4 EMD58993.1 - 0.021 14.2 0.5 0.035 13.5 0.3 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Brevenin PF03032.10 EMD58993.1 - 2.3 8.1 14.3 4.9 7.0 5.9 2.8 3 0 0 3 3 3 0 Brevenin/esculentin/gaegurin/rugosin family Cupredoxin_1 PF13473.1 EMD58996.1 - 0.006 16.4 0.2 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain DUF11 PF01345.13 EMD58996.1 - 0.018 15.0 1.5 0.018 15.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 Cu_bind_like PF02298.12 EMD58996.1 - 0.018 14.8 0.4 0.2 11.4 0.3 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.15 EMD58996.1 - 0.099 12.8 2.0 0.33 11.2 1.4 1.9 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family FAD_binding_4 PF01565.18 EMD58997.1 - 3.9e-28 97.6 0.5 3.9e-28 97.6 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMD58997.1 - 0.00026 20.8 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DNA_pol_B PF00136.16 EMD58998.1 - 1.5e-145 485.5 1.0 2.7e-145 484.7 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMD58998.1 - 1.2e-82 277.4 0.2 2.4e-82 276.4 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMD58998.1 - 2e-22 78.9 7.3 2e-22 78.9 5.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EMD58998.1 - 3.1e-06 26.8 0.1 7.9e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMD58998.1 - 0.0022 17.7 0.4 0.0077 16.0 0.3 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EMD58998.1 - 0.0069 15.0 3.3 0.046 12.3 0.0 2.5 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EMD58998.1 - 0.17 11.6 10.1 0.19 11.4 0.7 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_1 PF00583.19 EMD58999.1 - 1.4e-06 28.2 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMD58999.1 - 1.8e-05 24.5 0.2 0.0015 18.3 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD58999.1 - 4.8e-05 23.4 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD58999.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD58999.1 - 0.00039 20.2 0.0 0.0011 18.8 0.0 1.7 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Amidohydro_2 PF04909.9 EMD59000.1 - 2e-39 135.8 0.0 2.3e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EMD59000.1 - 0.011 14.9 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 TatD related DNase UxaC PF02614.9 EMD59000.1 - 0.21 10.1 0.1 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Glucuronate isomerase Pyridoxal_deC PF00282.14 EMD59001.1 - 1.4e-124 415.3 0.0 1.7e-124 415.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EMD59001.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPRY PF00622.23 EMD59002.1 - 0.021 14.8 0.0 0.48 10.5 0.0 3.0 3 1 0 3 3 3 0 SPRY domain Bystin PF05291.6 EMD59003.1 - 3.4e-124 413.7 0.0 7.4e-124 412.5 0.0 1.5 2 0 0 2 2 2 1 Bystin Pyr_redox_2 PF07992.9 EMD59004.1 - 1.8e-28 99.7 0.0 2e-17 63.7 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD59004.1 - 6.6e-13 48.8 0.0 1.8e-11 44.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD59004.1 - 0.00084 19.4 0.2 0.79 9.7 0.1 3.3 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase PQ-loop PF04193.9 EMD59005.1 - 7.5e-15 54.2 0.5 1.5e-14 53.2 0.4 1.5 1 0 0 1 1 1 1 PQ loop repeat YrhC PF14143.1 EMD59005.1 - 0.11 12.4 0.4 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 YrhC-like protein Antifungal_pept PF11410.3 EMD59006.1 - 0.79 9.8 9.6 0.26 11.4 4.1 2.2 2 1 0 2 2 2 0 Antifungal peptide DIOX_N PF14226.1 EMD59009.1 - 2.6e-23 82.7 0.0 4.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD59009.1 - 1.6e-17 63.5 0.0 3.6e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_20 PF00728.17 EMD59010.1 - 9.7e-36 123.6 2.9 4.9e-35 121.3 2.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EMD59010.1 - 1.2e-07 32.3 0.0 3.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 FAD_binding_4 PF01565.18 EMD59011.1 - 5.3e-14 51.8 0.0 8.7e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amidohydro_3 PF07969.6 EMD59011.1 - 0.015 14.5 0.1 0.067 12.4 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase family IPPT PF01715.12 EMD59013.1 - 5.7e-58 195.9 0.0 9e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 EMD59013.1 - 4.5e-05 23.7 1.0 0.0087 16.3 0.7 2.7 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EMD59013.1 - 6.3e-05 22.2 0.0 0.0005 19.3 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EMD59013.1 - 7.8e-05 23.4 0.1 0.00023 21.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD59013.1 - 0.00023 21.0 1.5 0.016 15.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.3 EMD59013.1 - 0.0064 16.6 0.1 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.1 EMD59013.1 - 0.044 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMD59013.1 - 0.2 11.4 1.9 0.82 9.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF3328 PF11807.3 EMD59014.1 - 1.7e-28 99.8 0.0 2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Mei4 PF13971.1 EMD59015.1 - 0.00046 19.2 0.3 0.0013 17.8 0.0 1.7 2 0 0 2 2 2 1 Meiosis-specific protein Mei4 PBP PF01161.15 EMD59016.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Milton PF12448.3 EMD59016.1 - 4.2 7.5 8.2 2.3 8.3 0.4 2.5 1 1 1 2 2 2 0 Kinesin associated protein Ribosomal_L4 PF00573.17 EMD59017.1 - 2.9e-47 160.5 0.0 7.1e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TPR_14 PF13428.1 EMD59017.1 - 3.4 8.5 6.1 0.8 10.5 1.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat IF3_C PF00707.17 EMD59018.1 - 5.6e-08 32.4 0.0 1.4e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EMD59018.1 - 0.0009 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EMD59018.1 - 0.0098 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor ATG16 PF08614.6 EMD59019.1 - 3.9e-38 131.2 17.3 4.5e-38 131.0 12.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EMD59019.1 - 0.0062 16.3 2.9 0.0062 16.3 2.0 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 EMD59019.1 - 0.015 15.0 0.5 0.015 15.0 0.3 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 EMD59019.1 - 0.025 14.0 16.8 0.052 12.9 11.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DivIC PF04977.10 EMD59019.1 - 0.026 14.0 16.0 0.12 11.8 2.0 3.0 2 1 1 3 3 3 0 Septum formation initiator IncA PF04156.9 EMD59019.1 - 0.028 14.0 15.1 0.028 14.0 3.0 2.1 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EMD59019.1 - 0.21 10.7 17.5 0.08 12.1 1.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding GOLGA2L5 PF15070.1 EMD59019.1 - 0.23 9.9 14.0 0.45 8.9 9.5 1.6 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 APG6 PF04111.7 EMD59019.1 - 0.6 9.1 16.3 0.49 9.4 10.0 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 EMD59019.1 - 0.94 9.2 6.1 2.2 8.0 1.2 3.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF972 PF06156.8 EMD59019.1 - 0.99 9.7 15.4 4.4 7.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fez1 PF06818.10 EMD59019.1 - 2 8.3 18.7 3.5 7.6 9.8 2.1 1 1 1 2 2 2 0 Fez1 Lectin_N PF03954.9 EMD59019.1 - 2.2 7.7 5.6 6.3 6.2 3.9 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2984 PF11203.3 EMD59019.1 - 2.5 8.2 14.2 3.8 7.6 6.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) FlaC_arch PF05377.6 EMD59019.1 - 2.6 8.0 6.5 7.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 EMD59019.1 - 3.3 5.4 6.1 4.1 5.1 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 EMD59019.1 - 3.7 7.7 22.6 2.1 8.5 4.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) SlyX PF04102.7 EMD59019.1 - 4.8 7.6 13.1 0.38 11.1 1.5 3.0 1 1 1 2 2 2 0 SlyX ERM PF00769.14 EMD59019.1 - 5.3 6.5 25.7 7.3 6.0 5.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4140 PF13600.1 EMD59019.1 - 5.6 7.4 15.4 0.26 11.7 1.3 3.0 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) JAB PF01398.16 EMD59020.1 - 4.4e-29 100.5 0.1 9e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMD59020.1 - 7.3e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EMD59020.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) tRNA-synt_1c PF00749.16 EMD59021.1 - 8e-97 323.6 0.0 1.1e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 EMD59022.1 - 6.9e-22 77.1 0.2 6.9e-20 70.7 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 EMD59022.1 - 2e-21 75.4 4.8 3.7e-21 74.6 3.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMD59022.1 - 6.9e-14 51.6 19.0 1.5e-13 50.5 13.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 EMD59022.1 - 0.33 11.3 4.0 0.85 9.9 2.8 1.7 1 0 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 EMD59022.1 - 0.48 10.1 6.4 0.44 10.2 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EMD59022.1 - 4.8 7.4 6.7 8.6 6.6 0.3 2.4 2 0 0 2 2 2 0 CHY zinc finger NYD-SP28_assoc PF14775.1 EMD59024.1 - 0.029 14.0 0.0 0.14 11.9 0.0 2.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF3784 PF12650.2 EMD59024.1 - 0.034 14.0 1.9 0.062 13.2 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF3623 PF12291.3 EMD59024.1 - 0.049 12.5 4.3 0.069 12.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) TcpE PF12648.2 EMD59024.1 - 1.2 9.3 5.5 2.4 8.3 3.8 1.5 1 0 0 1 1 1 0 TcpE family FA_desaturase PF00487.19 EMD59024.1 - 1.9 7.8 4.3 2.7 7.3 3.0 1.5 1 1 0 1 1 1 0 Fatty acid desaturase DUF4131 PF13567.1 EMD59024.1 - 2.1 7.7 5.6 2.9 7.2 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MARVEL PF01284.18 EMD59024.1 - 6 6.6 12.1 18 5.1 8.6 1.5 1 1 0 1 1 1 0 Membrane-associating domain CorA PF01544.13 EMD59025.1 - 1.2e-06 27.7 0.1 1.8e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HhH-GPD PF00730.20 EMD59026.1 - 0.00013 22.1 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ATG22 PF11700.3 EMD59027.1 - 8.6e-171 568.5 14.3 9.8e-171 568.4 9.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EMD59027.1 - 3.1e-05 22.8 45.4 0.00019 20.2 9.4 3.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2946 PF11162.3 EMD59027.1 - 0.28 11.3 6.1 0.75 10.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2946) B12D PF06522.6 EMD59027.1 - 1.8 8.3 8.0 0.84 9.3 1.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Prp19_bind PF06991.6 EMD59028.1 - 2.4e-51 174.6 22.3 2.4e-51 174.6 15.4 2.2 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain Serglycin PF04360.7 EMD59028.1 - 0.00069 19.3 3.3 0.0012 18.5 2.3 1.3 1 0 0 1 1 1 1 Serglycin Y2_Tnp PF04986.8 EMD59028.1 - 1.8 8.2 8.1 24 4.6 5.6 2.2 1 1 0 1 1 1 0 Putative transposase Cyclin PF08613.6 EMD59030.1 - 1.6e-16 61.0 0.0 3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMD59030.1 - 0.00058 19.4 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 EMD59033.1 - 1.2e-14 54.8 0.1 2.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GDPD PF03009.12 EMD59035.1 - 5.9e-20 71.8 0.0 1e-19 71.0 0.0 1.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DNA_gyraseA_C PF03989.8 EMD59035.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Zn_clus PF00172.13 EMD59038.1 - 2.2e-08 33.8 7.0 4.1e-08 33.0 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD59038.1 - 3e-06 26.3 0.1 4.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HOOK PF05622.7 EMD59038.1 - 0.0057 14.5 0.3 0.008 14.0 0.2 1.1 1 0 0 1 1 1 1 HOOK protein Cytochrome_C7 PF14522.1 EMD59038.1 - 0.52 9.9 6.0 0.87 9.2 3.2 2.0 2 0 0 2 2 2 0 Cytochrome c7 AAA_10 PF12846.2 EMD59039.1 - 4.3e-08 32.9 0.0 5.1e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.12 EMD59039.1 - 0.00017 21.5 0.1 0.057 13.2 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMD59039.1 - 0.0059 16.1 0.0 0.075 12.5 0.0 2.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EMD59039.1 - 0.0065 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EMD59039.1 - 0.0094 16.0 0.0 0.68 10.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMD59039.1 - 0.023 14.7 0.0 0.076 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF853 PF05872.7 EMD59039.1 - 0.067 11.5 0.0 0.22 9.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.4 EMD59039.1 - 0.074 11.6 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 EMD59039.1 - 0.093 12.1 0.0 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Ribonucleas_3_3 PF14622.1 EMD59040.1 - 3.1e-06 27.1 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD59040.1 - 0.013 15.9 0.1 0.058 13.8 0.1 1.9 1 1 0 1 1 1 0 Ribonuclease III domain YopJ PF03421.11 EMD59040.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Lactonase PF10282.4 EMD59041.1 - 8.4e-26 90.8 0.2 1.4e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MmgE_PrpD PF03972.9 EMD59042.1 - 4.9e-72 242.5 0.2 5.9e-72 242.2 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Fungal_trans PF04082.13 EMD59043.1 - 1.5e-27 96.1 0.6 2.7e-27 95.3 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD59043.1 - 1.7e-07 31.0 6.9 3e-07 30.2 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 EMD59044.1 - 2.7e-23 82.9 0.0 3.7e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DLH PF01738.13 EMD59044.1 - 2e-20 73.0 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short PF00106.20 EMD59044.1 - 2.8e-20 72.9 0.4 4e-20 72.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 EMD59044.1 - 7.3e-07 29.0 0.1 8.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family KR PF08659.5 EMD59044.1 - 0.00089 18.9 0.2 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Peptidase_S9 PF00326.16 EMD59044.1 - 0.0073 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family 3HCDH_N PF02737.13 EMD59044.1 - 0.14 11.8 0.2 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HS1_rep PF02218.10 EMD59044.1 - 0.37 10.7 2.0 0.5 10.2 0.1 2.2 2 0 0 2 2 2 0 Repeat in HS1/Cortactin MFS_1 PF07690.11 EMD59045.1 - 2.8e-31 108.5 28.1 3.7e-31 108.1 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fasciclin PF02469.17 EMD59046.1 - 6e-31 107.1 0.0 2.4e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain IDO PF01231.13 EMD59047.1 - 2.2e-51 174.6 0.0 3.6e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GTP_EFTU PF00009.22 EMD59047.1 - 4.4e-21 75.1 0.0 8.1e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMD59047.1 - 4.5e-14 52.4 0.1 1e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD59047.1 - 2.4e-10 40.3 2.3 1.7e-09 37.6 1.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EMD59047.1 - 0.007 15.8 0.9 0.62 9.5 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMD59047.1 - 0.027 14.9 0.1 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU_D4 PF14578.1 EMD59047.1 - 0.043 13.4 0.1 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMD59047.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Fmp27 PF10344.4 EMD59048.1 - 3.1e-206 686.9 0.0 4.9e-206 686.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EMD59048.1 - 1.3e-156 522.0 1.2 1.3e-156 522.0 0.8 2.4 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EMD59048.1 - 1.6e-147 491.7 4.9 1.6e-147 491.7 3.4 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EMD59048.1 - 2e-56 190.2 0.0 4.8e-56 189.0 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EMD59048.1 - 7.1e-53 178.5 0.2 1.5e-52 177.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EMD59048.1 - 1e-31 109.4 0.0 3.5e-31 107.6 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Polysacc_deac_1 PF01522.16 EMD59050.1 - 3.4e-15 55.7 0.0 8.8e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF427 PF04248.7 EMD59052.1 - 2.5e-35 120.0 0.7 1.9e-30 104.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Fringe PF02434.11 EMD59053.1 - 5.5e-09 35.5 0.0 3.5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EMD59053.1 - 0.0025 17.5 2.7 0.0053 16.4 1.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EMD59053.1 - 0.094 12.3 0.5 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 PAN-like domain Galactosyl_T PF01762.16 EMD59053.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Galactosyltransferase ABC_tran PF00005.22 EMD59055.1 - 6.1e-16 58.9 0.0 5.9e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMD59055.1 - 4.7e-11 43.1 1.2 0.00024 21.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EMD59055.1 - 4.3e-06 26.0 0.0 0.031 13.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EMD59055.1 - 0.00012 21.3 0.0 0.046 12.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EMD59055.1 - 0.00028 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EMD59055.1 - 0.00039 19.8 0.6 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EMD59055.1 - 0.0013 16.1 0.1 0.0017 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 EMD59055.1 - 0.0018 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EMD59055.1 - 0.0029 17.9 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD59055.1 - 0.0079 15.6 0.1 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EMD59055.1 - 0.019 14.4 0.1 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 EMD59055.1 - 0.024 14.8 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD59055.1 - 0.024 15.4 0.1 0.05 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMD59055.1 - 0.03 14.3 0.2 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD59055.1 - 0.034 14.1 0.7 0.072 13.0 0.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EMD59055.1 - 0.05 13.5 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMD59055.1 - 0.059 12.4 0.1 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Phage_lambd_GpG PF06894.6 EMD59055.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) DUF258 PF03193.11 EMD59055.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMD59055.1 - 0.084 13.0 0.5 0.65 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 EMD59055.1 - 0.1 11.8 0.3 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_13 PF13166.1 EMD59055.1 - 0.2 10.0 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain F-box PF00646.28 EMD59056.1 - 0.0048 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain gag-asp_proteas PF13975.1 EMD59056.1 - 0.0069 16.1 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease F-box-like PF12937.2 EMD59056.1 - 0.077 12.7 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 F-box-like ADH_zinc_N PF00107.21 EMD59057.1 - 5.3e-28 97.1 0.3 7.8e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD59057.1 - 1.4e-26 92.3 5.2 6.5e-26 90.2 2.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD59057.1 - 1.5e-05 25.8 0.0 3.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EMD59057.1 - 0.073 13.0 0.7 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding PUA PF01472.15 EMD59057.1 - 0.075 12.7 0.9 0.37 10.5 0.1 2.4 2 0 0 2 2 2 0 PUA domain DUF4472 PF14739.1 EMD59059.1 - 6.9 7.1 38.2 0.36 11.3 2.9 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4472) ATG22 PF11700.3 EMD59060.1 - 1.4e-133 445.8 28.4 1.6e-133 445.6 19.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EMD59060.1 - 4.5e-14 51.9 27.0 5e-08 32.0 2.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily p450 PF00067.17 EMD59061.1 - 3.6e-29 101.5 1.0 2.5e-27 95.5 0.7 2.3 1 1 1 2 2 2 2 Cytochrome P450 DUF4274 PF14096.1 EMD59061.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) APH PF01636.18 EMD59062.1 - 0.00011 21.9 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMD59062.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EMD59062.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tyr-DNA_phospho PF06087.7 EMD59064.1 - 9.4e-75 251.9 0.0 1.2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EMD59064.1 - 2.1e-05 24.2 0.0 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EMD59064.1 - 0.00038 19.7 0.2 0.00038 19.7 0.2 2.6 3 0 0 3 3 3 1 Ubiquitin interaction motif Urm1 PF09138.6 EMD59065.1 - 9.7e-34 115.3 0.0 1.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EMD59065.1 - 0.0056 17.0 0.0 0.0068 16.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family WD40 PF00400.27 EMD59066.1 - 8.7e-63 206.1 28.3 6e-10 38.6 0.1 13.4 14 0 0 14 14 14 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD59066.1 - 2.6e-09 36.8 0.0 0.00096 18.9 0.0 5.8 7 0 0 7 7 7 2 Ciliary BBSome complex subunit 2, middle region DUF3302 PF11742.3 EMD59067.1 - 0.083 12.7 0.0 0.083 12.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3302) PLDc_N PF13396.1 EMD59067.1 - 2.1 8.0 0.0 2.1 8.0 0.0 3.6 3 1 1 4 4 4 0 Phospholipase_D-nuclease N-terminal Ndc1_Nup PF09531.5 EMD59067.1 - 3 6.1 6.5 4.6 5.5 4.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2975 PF11188.3 EMD59067.1 - 9.9 5.8 9.0 1.3e+02 2.2 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) UEV PF05743.8 EMD59068.1 - 1.1e-36 125.1 0.0 1.8e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EMD59068.1 - 7.1e-24 83.1 0.0 1.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain Aminotran_5 PF00266.14 EMD59069.1 - 2.2e-96 322.8 0.0 2.7e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMD59069.1 - 9.7e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD59069.1 - 0.00048 19.2 0.1 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EMD59069.1 - 0.11 10.8 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 EMD59070.1 - 3.9e-62 209.7 9.3 4.9e-62 209.4 6.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMD59070.1 - 3e-14 52.1 0.1 5.2e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD59070.1 - 9.5e-13 47.5 0.1 1.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMD59070.1 - 1.1e-10 40.8 0.0 1.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EMD59070.1 - 0.02 14.1 5.6 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Vps5 C terminal like NolV PF06635.7 EMD59070.1 - 0.039 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV TMPIT PF07851.8 EMD59070.1 - 3 6.8 6.5 0.28 10.2 0.2 1.9 1 1 0 2 2 2 0 TMPIT-like protein DSBA PF01323.15 EMD59071.1 - 8.3e-20 71.1 0.0 9.4e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GTP_cyclohydro2 PF00925.15 EMD59073.1 - 3.8e-57 192.2 0.0 1.1e-50 171.1 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II WD40 PF00400.27 EMD59074.1 - 3.4e-104 337.3 63.4 1.8e-13 49.7 0.3 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat HET PF06985.6 EMD59074.1 - 7.9e-24 84.4 2.7 3.5e-22 79.0 1.9 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMD59074.1 - 1.1e-20 73.9 0.1 2.1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD59074.1 - 3.2e-19 68.4 36.0 0.0049 15.0 0.2 8.2 1 1 7 8 8 8 8 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD59074.1 - 0.0053 15.5 21.1 0.37 9.5 2.3 3.7 1 1 2 3 3 3 2 Nup133 N terminal like AAA_22 PF13401.1 EMD59074.1 - 0.017 15.2 0.1 0.52 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD59074.1 - 0.097 12.4 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Cytochrom_D1 PF02239.11 EMD59074.1 - 0.16 10.2 4.9 1.8 6.8 0.1 3.0 1 1 2 3 3 3 0 Cytochrome D1 heme domain CitT PF12431.3 EMD59075.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Sugar_tr PF00083.19 EMD59076.1 - 5.9e-85 285.5 10.1 9.4e-85 284.8 7.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59076.1 - 4e-29 101.4 36.0 3.6e-22 78.5 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD59076.1 - 0.00037 18.8 2.3 0.00037 18.8 1.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EMD59077.1 - 8.2e-65 218.5 0.0 1e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD59077.1 - 6.9e-32 110.5 0.0 4e-31 108.0 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMD59077.1 - 0.012 15.3 0.0 0.45 10.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD59077.1 - 0.053 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CAP PF00188.21 EMD59078.1 - 1.8e-19 70.4 1.2 2.4e-19 70.0 0.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Heme_oxygenase PF01126.15 EMD59079.1 - 4.3e-11 42.7 0.0 4.5e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase DUF1657 PF07870.6 EMD59079.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) PNP_UDP_1 PF01048.15 EMD59080.1 - 2.6e-08 33.1 2.3 2.8e-07 29.7 1.6 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily UBA_3 PF09288.5 EMD59080.1 - 0.034 13.7 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CorA PF01544.13 EMD59081.1 - 2.8e-07 29.8 0.8 3.4e-07 29.5 0.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4027 PF13219.1 EMD59082.1 - 0.2 11.1 0.7 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) NACHT PF05729.7 EMD59083.1 - 1.1e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD59083.1 - 1.4e-06 28.3 0.9 5.2e-06 26.5 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD59083.1 - 0.0018 18.3 0.0 0.0085 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EMD59083.1 - 0.0031 17.2 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_19 PF13245.1 EMD59083.1 - 0.0047 16.6 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMD59083.1 - 0.015 16.1 0.0 0.1 13.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMD59083.1 - 0.023 14.8 0.1 0.12 12.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMD59083.1 - 0.065 12.0 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EMD59083.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD59083.1 - 0.14 12.4 0.1 0.93 9.7 0.0 2.5 4 0 0 4 4 4 0 AAA domain KAP_NTPase PF07693.9 EMD59083.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain WD40 PF00400.27 EMD59084.1 - 1.3e-63 208.7 8.1 2.5e-14 52.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EMD59084.1 - 1.9e-12 46.2 0.1 1.7 8.0 0.0 6.2 6 0 0 6 6 6 4 Proteasome subunit A N-terminal signature Nup160 PF11715.3 EMD59084.1 - 4.6e-10 38.2 10.4 0.002 16.3 0.1 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Stimulus_sens_1 PF13756.1 EMD59084.1 - 9.6e-10 38.8 0.3 2 8.8 0.0 4.5 3 1 0 4 4 4 4 Stimulus-sensing domain eIF2A PF08662.6 EMD59084.1 - 9.1e-08 32.0 0.0 0.067 12.8 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Robl_LC7 PF03259.12 EMD59084.1 - 1.3e-07 31.0 1.2 3.6 7.2 0.0 4.2 2 2 2 4 4 4 3 Roadblock/LC7 domain IKI3 PF04762.7 EMD59084.1 - 5.4e-07 27.8 0.3 0.02 12.7 0.0 2.8 1 1 2 3 3 3 3 IKI3 family TruB_C PF09142.6 EMD59084.1 - 5.6e-07 29.1 1.4 4.7 6.9 0.0 5.0 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.7 EMD59084.1 - 6.3e-07 28.9 0.0 3.5 7.3 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat 4HBT_3 PF13622.1 EMD59084.1 - 1.6e-05 24.8 4.6 3.7 7.2 0.0 4.1 2 1 1 4 4 4 1 Thioesterase-like superfamily NodS PF05401.6 EMD59084.1 - 0.00036 19.9 1.4 3.5 6.9 0.0 4.0 1 1 3 4 4 4 1 Nodulation protein S (NodS) Nucleoporin_N PF08801.6 EMD59084.1 - 0.00037 19.3 0.2 0.61 8.7 0.0 3.3 1 1 2 3 3 3 1 Nup133 N terminal like MannoseP_isomer PF01050.13 EMD59084.1 - 0.00066 19.3 0.1 5.4 6.6 0.0 3.8 1 1 3 4 4 4 1 Mannose-6-phosphate isomerase Coatomer_WDAD PF04053.9 EMD59084.1 - 0.0016 17.3 0.0 2.7 6.6 0.0 3.3 1 1 2 3 3 3 2 Coatomer WD associated region PRTase_2 PF15609.1 EMD59084.1 - 0.0068 15.7 0.2 4.5 6.5 0.0 3.0 1 1 2 3 3 3 1 Phosphoribosyl transferase Cytochrom_D1 PF02239.11 EMD59084.1 - 0.0099 14.2 0.2 1.6 6.9 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF2415 PF10313.4 EMD59084.1 - 0.011 15.3 0.2 87 2.9 0.0 4.3 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) SMP_2 PF10144.4 EMD59084.1 - 0.033 13.2 0.0 26 3.8 0.0 3.7 1 1 3 4 4 4 0 Bacterial virulence factor haemolysin DUF1258 PF06869.7 EMD59084.1 - 0.05 12.6 0.7 20 4.1 0.0 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) PSD5 PF07637.6 EMD59084.1 - 0.059 13.4 0.0 73 3.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) DUF2411 PF10304.4 EMD59084.1 - 0.11 12.0 0.0 2.1e+02 1.5 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF2411) DUF982 PF06169.7 EMD59084.1 - 0.59 9.9 6.7 28 4.5 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF982) zf-C2H2_4 PF13894.1 EMD59085.1 - 8.8e-09 35.0 15.9 0.0021 18.2 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD59085.1 - 0.00044 20.4 26.0 0.044 14.1 0.1 4.4 4 1 0 4 4 4 3 Zinc finger, C2H2 type IBR PF01485.16 EMD59085.1 - 0.0011 18.8 3.5 1.1 9.1 0.0 3.0 2 1 1 3 3 3 2 IBR domain zf-Di19 PF05605.7 EMD59085.1 - 0.019 15.0 3.2 3.2 7.9 1.4 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EMD59085.1 - 3.1 8.2 0.0 3.1 8.2 0.0 3.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain UQ_con PF00179.21 EMD59086.1 - 7.7e-22 77.2 0.0 1.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COesterase PF00135.23 EMD59087.1 - 3.7e-96 322.9 0.0 4.7e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMD59087.1 - 8.1e-05 21.9 0.2 0.00012 21.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMD59087.1 - 8.1e-05 22.2 0.1 0.00075 19.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FA_desaturase PF00487.19 EMD59090.1 - 1.4e-25 90.2 21.7 2.3e-25 89.5 15.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMD59090.1 - 1.1e-06 28.7 0.1 2.3e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RPE65 PF03055.10 EMD59091.1 - 4.7e-121 404.7 0.0 5.3e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1254 PF06863.7 EMD59092.1 - 1.4e-28 99.3 0.4 1.5e-27 95.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.6 EMD59092.1 - 3e-19 69.3 0.2 2.2e-18 66.6 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1214) Zn_clus PF00172.13 EMD59095.1 - 1.3e-06 28.1 14.3 1.3e-06 28.1 9.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EMD59095.1 - 0.24 10.3 0.3 0.44 9.4 0.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short PF00106.20 EMD59096.1 - 5e-16 59.0 0.1 1.3e-15 57.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD59096.1 - 0.00046 20.0 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMD59096.1 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMD59096.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACT_7 PF13840.1 EMD59096.1 - 0.029 13.8 0.1 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 ACT domain NAD_binding_10 PF13460.1 EMD59096.1 - 0.035 14.0 0.0 0.093 12.7 0.0 1.7 2 1 0 2 2 2 0 NADH(P)-binding Terpene_synth_C PF03936.11 EMD59097.1 - 7.5e-17 61.4 0.0 1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EMD59098.1 - 2.4e-64 217.5 0.0 2.9e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 EMD59099.1 - 5.8e-80 268.6 38.1 2.7e-46 158.2 13.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD59099.1 - 1.3e-68 229.5 0.0 9.2e-34 116.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD59099.1 - 1.8e-13 50.2 0.0 0.00066 18.9 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD59099.1 - 5.9e-12 46.1 2.3 0.022 14.7 0.8 4.3 2 2 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EMD59099.1 - 1e-08 34.5 0.5 0.0039 16.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EMD59099.1 - 7e-08 31.4 3.1 0.0085 14.7 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMD59099.1 - 3.4e-07 30.4 1.1 0.011 15.7 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMD59099.1 - 1.1e-06 27.9 0.5 0.025 13.7 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EMD59099.1 - 4.5e-06 26.3 0.1 0.23 11.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 EMD59099.1 - 6e-06 27.0 0.0 0.13 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD59099.1 - 1.8e-05 24.2 0.5 0.34 10.3 0.0 4.0 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.1 EMD59099.1 - 5.4e-05 22.4 0.0 0.21 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 EMD59099.1 - 5.5e-05 23.0 1.4 0.61 10.0 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMD59099.1 - 9.6e-05 22.7 0.0 0.12 12.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EMD59099.1 - 0.0004 20.1 0.1 1.1 8.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) PRK PF00485.13 EMD59099.1 - 0.00059 19.4 0.5 2.9 7.4 0.0 3.5 4 0 0 4 4 4 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EMD59099.1 - 0.00069 19.9 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EMD59099.1 - 0.0013 18.5 0.2 0.7 9.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EMD59099.1 - 0.0013 18.8 3.8 1.7 8.8 0.3 4.0 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMD59099.1 - 0.0031 17.5 0.0 3.7 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EMD59099.1 - 0.013 15.6 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EMD59099.1 - 0.016 14.3 0.0 0.69 8.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EMD59099.1 - 0.02 14.8 0.0 3 7.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD59099.1 - 0.021 14.3 0.0 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMD59099.1 - 0.023 14.1 2.6 9.8 5.5 0.0 4.0 4 0 0 4 4 4 0 AAA-like domain AAA_33 PF13671.1 EMD59099.1 - 0.032 14.1 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EMD59099.1 - 0.044 14.2 0.1 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 EMD59099.1 - 0.086 11.7 0.0 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EMD59099.1 - 0.11 12.4 0.5 8.4 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EMD59099.1 - 0.11 12.1 0.2 8 6.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EMD59099.1 - 0.14 10.8 0.0 6.7 5.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 EMD59099.1 - 0.21 10.4 0.1 19 3.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EMD59099.1 - 0.21 11.1 0.4 8.4 5.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AMP-binding PF00501.23 EMD59100.1 - 4.3e-77 259.2 0.1 8.7e-77 258.2 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 EMD59100.1 - 3.2e-26 91.8 0.2 5.7e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EMD59100.1 - 2e-08 34.3 0.1 4.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD59100.1 - 5.4e-06 27.2 0.0 2.3e-05 25.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EMD59101.1 - 4.4e-55 187.0 0.0 2.1e-54 184.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.15 EMD59102.1 - 1.2e-11 44.7 0.0 2.5e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TRI12 PF06609.8 EMD59103.1 - 4.9e-62 209.9 25.5 6.5e-62 209.5 17.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMD59103.1 - 2.2e-18 66.1 49.8 2.4e-18 66.0 31.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59103.1 - 6.8e-10 38.0 16.6 1.3e-09 37.2 3.2 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter Pox_A14 PF05767.7 EMD59103.1 - 0.0045 16.9 0.2 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Hexapep_2 PF14602.1 EMD59103.1 - 0.37 10.3 3.6 11 5.6 0.6 2.9 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase PIRT PF15099.1 EMD59103.1 - 6.5 5.9 8.2 1.1 8.4 0.2 3.2 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family COesterase PF00135.23 EMD59104.1 - 5e-76 256.5 0.1 6.6e-76 256.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD59104.1 - 9.1e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMD59104.1 - 0.0041 15.8 0.1 0.012 14.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) p450 PF00067.17 EMD59105.1 - 2.6e-66 224.0 0.0 3.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EMD59106.1 - 1.2e-31 109.6 0.0 6.2e-10 38.1 0.0 3.2 3 0 0 3 3 3 3 Transferase family NYN_YacP PF05991.6 EMD59106.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 YacP-like NYN domain p450 PF00067.17 EMD59107.1 - 3.1e-40 138.0 0.0 3.8e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.15 EMD59108.1 - 1.9e-123 411.5 0.0 6.4e-123 409.8 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD59108.1 - 8.9e-13 47.9 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMD59108.1 - 4e-10 38.9 0.1 7.3e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMD59108.1 - 1.7e-06 27.3 0.2 2.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMD59108.1 - 2.5e-05 23.5 0.1 0.0001 21.6 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 EMD59108.1 - 0.0097 14.6 0.0 0.028 13.1 0.0 1.7 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase GDC-P PF02347.11 EMD59108.1 - 0.049 12.3 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein COesterase PF00135.23 EMD59109.1 - 1.6e-25 89.8 0.2 4e-11 42.3 0.0 3.6 1 1 1 2 2 2 2 Carboxylesterase family DUF438 PF04282.8 EMD59110.1 - 0.036 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) Bac_rhamnosid PF05592.6 EMD59112.1 - 9.7e-143 476.0 0.0 2.2e-142 474.8 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EMD59112.1 - 1.3e-32 112.6 0.0 2.7e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain HET PF06985.6 EMD59113.1 - 8.8e-19 68.0 1.6 5e-14 52.6 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 EMD59114.1 - 2.6e-25 87.3 2.2 1e-11 44.2 0.3 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 EMD59114.1 - 7.3e-06 24.3 3.9 0.0089 14.2 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 EMD59114.1 - 0.0033 16.8 0.7 0.021 14.2 0.1 2.0 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EMD59114.1 - 0.024 13.4 0.7 0.051 12.3 0.5 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Nbas_N PF15492.1 EMD59114.1 - 0.052 12.6 2.2 2.1 7.3 0.1 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_B562 PF07361.6 EMD59115.1 - 0.067 13.5 0.1 0.079 13.3 0.1 1.0 1 0 0 1 1 1 0 Cytochrome b562 DUF1412 PF07203.6 EMD59117.1 - 0.043 13.7 0.1 9.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) DUF1517 PF07466.6 EMD59118.1 - 0.019 13.9 1.7 0.026 13.5 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TrbC PF04956.8 EMD59118.1 - 0.042 13.8 1.3 0.08 12.9 0.9 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family AHS2 PF02626.10 EMD59119.1 - 2.6e-51 174.5 0.0 3.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 AHS1 PF02682.11 EMD59119.1 - 8.7e-14 51.4 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_lipoyl PF00364.17 EMD59119.1 - 7.3e-08 31.9 0.3 7.3e-07 28.7 0.1 2.5 2 1 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMD59119.1 - 0.00014 21.4 0.5 0.00074 19.1 0.1 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_carb_C PF02785.14 EMD59119.1 - 0.00027 20.8 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HlyD PF00529.15 EMD59119.1 - 0.02 14.2 0.1 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 EMD59119.1 - 0.034 13.3 0.1 0.065 12.3 0.0 1.4 1 1 0 1 1 1 0 HlyD family secretion protein RnfC_N PF13375.1 EMD59119.1 - 0.15 11.7 0.1 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PHD PF00628.24 EMD59120.1 - 8.2e-11 41.4 7.1 1.4e-10 40.7 4.9 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EMD59120.1 - 7.4e-05 22.9 0.5 0.00051 20.2 0.0 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EMD59120.1 - 0.027 14.5 1.3 0.056 13.5 0.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain RAG2_PHD PF13341.1 EMD59120.1 - 0.051 13.5 0.4 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 RAG2 PHD domain HCO3_cotransp PF00955.16 EMD59122.1 - 2.4e-68 231.0 13.9 8.8e-41 140.1 3.2 2.2 1 1 1 2 2 2 2 HCO3- transporter family Phage_TAC PF06222.6 EMD59123.1 - 0.014 14.9 0.4 0.044 13.3 0.3 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF4611 PF15387.1 EMD59124.1 - 0.084 13.0 4.2 0.2 11.8 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-Di19 PF05605.7 EMD59125.1 - 0.059 13.4 0.6 0.059 13.4 0.4 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_22 PF13401.1 EMD59125.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEADboxA PF12343.3 EMD59125.1 - 0.5 10.6 5.9 1.5 9.1 4.1 1.8 1 0 0 1 1 1 0 Cold shock protein DEAD box A Phosphodiest PF01663.17 EMD59127.1 - 7.3e-13 48.5 0.1 1.4e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMD59127.1 - 4.7e-05 22.8 1.0 8.5e-05 22.0 0.7 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EMD59127.1 - 0.00049 19.3 0.2 0.0028 16.8 0.1 2.3 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.12 EMD59127.1 - 0.46 8.8 0.0 0.67 8.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PilX_N PF14341.1 EMD59128.1 - 0.018 14.7 1.0 0.032 13.9 0.7 1.3 1 0 0 1 1 1 0 PilX N-terminal PUF PF00806.14 EMD59130.1 - 2.8e-61 199.6 5.9 1.5e-08 33.6 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF4372 PF14294.1 EMD59130.1 - 0.015 15.1 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Thioredox_DsbH PF03190.10 EMD59132.1 - 2.3e-73 245.2 0.0 3.7e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EMD59132.1 - 5.6e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD59132.1 - 0.0024 18.0 0.0 0.0072 16.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_9 PF00759.14 EMD59132.1 - 0.011 14.6 0.3 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 HTH_10 PF04967.7 EMD59132.1 - 0.039 13.5 0.5 0.3 10.7 0.0 2.7 4 0 0 4 4 4 0 HTH DNA binding domain Glyco_hydro_76 PF03663.9 EMD59132.1 - 0.055 12.8 2.2 0.19 11.0 0.3 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 76 Rnk_N PF14760.1 EMD59132.1 - 0.059 13.4 0.3 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Rnk N-terminus Glyco_hydro_88 PF07470.8 EMD59132.1 - 0.073 12.0 0.5 10 5.0 0.1 2.8 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 EMD59133.1 - 3.7e-43 147.6 28.3 3.7e-43 147.6 19.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC119_bdg PF15435.1 EMD59134.1 - 0.031 13.6 1.1 0.2 10.9 0.0 2.1 1 1 1 2 2 2 0 UNC119-binding protein C5orf30 homologue F-box-like PF12937.2 EMD59135.1 - 4.5e-05 23.0 1.5 8.2e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD59135.1 - 0.011 15.3 0.1 0.029 14.0 0.1 1.8 1 0 0 1 1 1 0 F-box domain Transket_pyr PF02779.19 EMD59137.1 - 0.07 12.6 0.1 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain zf-Apc11 PF12861.2 EMD59137.1 - 0.14 12.0 0.8 0.24 11.2 0.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger vWA-TerF-like PF10138.4 EMD59138.1 - 0.037 13.8 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus YrhK PF14145.1 EMD59138.1 - 0.089 12.4 0.7 1.9 8.2 1.1 2.3 2 0 0 2 2 2 0 YrhK-like protein CorA PF01544.13 EMD59139.1 - 3.3e-08 32.9 0.2 5.8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short PF00106.20 EMD59140.1 - 2.6e-12 46.9 0.3 6.1e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD59140.1 - 1e-10 41.8 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Elong_Iki1 PF10483.4 EMD59141.1 - 1.7e-69 234.2 0.0 2.3e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1840 PF08895.6 EMD59141.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF1777 PF08648.7 EMD59143.1 - 1.9e-19 70.1 49.0 1.6e-18 67.0 33.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Glyco_hydro_63 PF03200.11 EMD59144.1 - 3.6e-247 822.2 0.0 2.8e-246 819.2 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMD59144.1 - 2.8e-08 32.8 0.7 2.8e-08 32.8 0.5 1.5 2 0 0 2 2 2 1 Trehalase GDE_C PF06202.9 EMD59144.1 - 0.00072 18.3 0.1 0.0014 17.4 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Surface_Ag_2 PF01617.12 EMD59144.1 - 0.062 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Surface antigen E1-E2_ATPase PF00122.15 EMD59147.1 - 9.1e-71 237.5 6.7 2.9e-70 235.9 0.1 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMD59147.1 - 2.4e-23 83.6 0.0 1e-22 81.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD59147.1 - 5.7e-13 48.1 0.0 1.4e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMD59147.1 - 8.7e-13 48.8 0.0 2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD59147.1 - 0.0014 18.2 0.7 0.011 15.3 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EMD59148.1 - 2.2e-29 102.2 34.2 2.2e-29 102.2 23.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59148.1 - 1.3e-16 60.2 21.1 4.7e-15 55.1 4.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Folate_carrier PF01770.13 EMD59148.1 - 0.0044 15.5 1.1 0.012 14.0 0.8 1.7 1 0 0 1 1 1 1 Reduced folate carrier PgpA PF04608.8 EMD59148.1 - 3.8 7.3 8.2 0.36 10.6 0.1 2.9 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A Actin PF00022.14 EMD59149.1 - 5.6e-159 528.7 0.0 6.3e-159 528.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMD59149.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EMD59150.1 - 7.4e-27 93.6 1.7 1.8e-26 92.4 1.2 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EMD59150.1 - 9e-07 29.0 0.6 3.2e-06 27.3 0.1 2.1 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EMD59150.1 - 3.1e-06 27.5 0.0 1e-05 25.8 0.0 2.0 1 0 0 1 1 1 1 HEAT-like repeat HEAT PF02985.17 EMD59150.1 - 5.4e-05 22.9 0.0 0.26 11.4 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.18 EMD59150.1 - 0.00028 20.5 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat SpoIIIAH PF12685.2 EMD59150.1 - 0.094 12.2 2.4 0.17 11.3 1.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2372 PF10178.4 EMD59151.1 - 0.00011 22.2 0.0 0.00061 19.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) HA2 PF04408.18 EMD59152.1 - 1.3e-17 63.6 0.2 1.3e-17 63.6 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMD59152.1 - 3e-15 55.8 0.0 2.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMD59152.1 - 1.8e-10 40.6 0.2 5.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EMD59152.1 - 3.1e-08 33.2 0.2 7.3e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMD59152.1 - 0.00013 22.0 0.3 0.00064 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EMD59152.1 - 0.21 11.3 0.0 0.21 11.3 0.0 4.0 5 1 1 6 6 6 0 Type III restriction enzyme, res subunit Sugar_tr PF00083.19 EMD59153.1 - 6.9e-75 252.3 25.4 8e-75 252.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59153.1 - 7.3e-17 61.1 27.4 7.3e-17 61.1 19.0 2.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_26 PF13659.1 EMD59154.1 - 9.7e-11 41.7 0.0 2.7e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD59154.1 - 7.3e-07 29.7 0.0 1e-05 26.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD59154.1 - 4.7e-05 23.0 0.0 9.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EMD59154.1 - 0.0099 15.0 0.0 0.029 13.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF890) Methyltransf_25 PF13649.1 EMD59154.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EMD59154.1 - 0.073 12.6 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 ATP_bind_4 PF01902.12 EMD59154.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP-binding region PAP2 PF01569.16 EMD59155.1 - 4.4e-16 58.7 4.5 4.4e-16 58.7 3.1 1.9 1 1 1 2 2 2 1 PAP2 superfamily Virul_fac_BrkB PF03631.10 EMD59155.1 - 0.0012 18.2 8.2 0.0017 17.7 5.7 1.4 1 1 0 1 1 1 1 Virulence factor BrkB DUF212 PF02681.9 EMD59155.1 - 0.0037 17.0 0.0 0.099 12.3 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family TauE PF01925.14 EMD59155.1 - 0.027 13.9 10.6 0.048 13.1 7.3 1.6 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Tim17 PF02466.14 EMD59155.1 - 0.36 10.8 2.1 0.72 9.9 1.5 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family IBR PF01485.16 EMD59156.1 - 2.4e-19 68.9 36.7 3.4e-13 49.2 0.5 4.1 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 EMD59156.1 - 1.7e-18 66.5 0.4 4.4e-18 65.2 0.2 1.7 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.1 EMD59156.1 - 0.004 16.9 11.5 0.004 16.9 8.0 3.7 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EMD59156.1 - 0.015 15.0 12.5 0.015 15.0 8.6 4.2 2 2 1 3 3 3 0 zinc-RING finger domain C1_4 PF07975.7 EMD59156.1 - 4 7.5 31.5 2.4 8.2 0.4 4.2 3 1 0 3 3 3 0 TFIIH C1-like domain FTA4 PF13093.1 EMD59157.1 - 0.016 14.6 1.5 0.031 13.7 1.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Pyr_excise PF03013.9 EMD59157.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Glyco_hydro_43 PF04616.9 EMD59159.1 - 8.9e-23 80.7 8.9 8.8e-22 77.5 6.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Gal_Lectin PF02140.13 EMD59160.1 - 0.19 12.0 8.2 1.2 9.4 5.7 2.0 1 1 0 1 1 1 0 Galactose binding lectin domain zf-C4 PF00105.13 EMD59160.1 - 0.6 10.3 5.2 0.48 10.6 2.5 1.7 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) C-term_anchor PF13461.1 EMD59162.1 - 0.19 12.1 0.9 1.1e+02 3.3 0.3 3.6 2 1 1 3 3 3 0 Cell-wall surface anchor repeat DUF3659 PF12396.3 EMD59162.1 - 1.4 8.6 5.4 1.9 8.2 2.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) RVT_2 PF07727.9 EMD59163.1 - 0.055 12.4 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 4HBT_2 PF13279.1 EMD59164.1 - 3.9e-07 30.5 0.0 5.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily SUI1 PF01253.17 EMD59165.1 - 4.2e-16 58.5 0.0 1.6e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 EMD59165.1 - 0.041 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain Kin17_mid PF10357.4 EMD59165.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Chromo PF00385.19 EMD59168.1 - 0.06 13.0 0.6 0.15 11.7 0.4 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 EMD59169.1 - 1.5e-63 212.9 0.2 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD59169.1 - 5.4e-22 78.5 0.1 8.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD59169.1 - 2.5e-13 49.6 0.1 3.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD59169.1 - 3.3e-08 33.4 0.1 5.3e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD59169.1 - 3.6e-05 23.2 0.1 0.00013 21.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD59169.1 - 6.6e-05 22.1 0.1 0.00011 21.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMD59169.1 - 0.0001 22.4 0.1 0.0003 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMD59169.1 - 0.0011 18.8 0.1 0.0028 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EMD59169.1 - 0.0018 17.4 0.1 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMD59169.1 - 0.0027 16.9 0.1 0.0058 15.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EMD59169.1 - 0.006 16.4 0.4 0.083 12.8 0.0 2.4 3 0 0 3 3 2 1 Stage III sporulation protein D SRPRB PF09439.5 EMD59169.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EMD59169.1 - 0.022 15.0 0.1 0.031 14.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMD59169.1 - 0.022 14.7 0.3 0.043 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EMD59169.1 - 0.025 14.1 0.1 0.056 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMD59169.1 - 0.081 12.1 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMD59169.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMD59169.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPT PF03151.11 EMD59170.1 - 8.5e-40 135.8 1.6 8.5e-40 135.8 1.1 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMD59170.1 - 2.9e-10 39.5 11.8 4.2e-09 35.7 8.2 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMD59170.1 - 2.4e-06 27.5 31.1 0.00046 20.2 8.5 3.4 2 2 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMD59170.1 - 0.011 14.8 1.3 0.041 12.9 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF914 PF06027.7 EMD59170.1 - 0.011 14.5 1.9 0.034 12.9 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Peptidase_S9 PF00326.16 EMD59171.1 - 3.2e-06 26.5 0.1 5.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD59171.1 - 7.9e-05 22.4 0.2 0.00015 21.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 EMD59171.1 - 0.052 12.0 0.0 0.096 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PUF PF00806.14 EMD59172.1 - 7.5e-34 113.3 4.9 8.1e-05 21.8 0.0 9.1 8 1 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EMD59172.1 - 0.079 13.6 0.1 0.64 10.7 0.0 2.2 2 0 0 2 2 2 0 Regulator of ribonuclease activity B HIG_1_N PF04588.8 EMD59173.1 - 2.4e-09 36.7 0.3 2.4e-09 36.7 0.2 2.3 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Gly-zipper_OmpA PF13436.1 EMD59173.1 - 6.8 6.3 7.8 0.55 9.8 0.6 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Picorna_P3A PF06363.6 EMD59174.1 - 0.088 12.8 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein RHD3 PF05879.7 EMD59175.1 - 0 1042.0 0.0 0 1041.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EMD59175.1 - 4.6e-08 32.4 0.1 8.3e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EMD59175.1 - 3e-06 27.1 0.0 8.2e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMD59175.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD59175.1 - 0.0028 18.1 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EMD59175.1 - 0.0036 17.2 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EMD59175.1 - 0.038 13.0 0.1 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Septin DAO PF01266.19 EMD59176.1 - 2.8e-43 148.2 0.0 3.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD59176.1 - 0.063 13.1 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WW PF00397.21 EMD59177.1 - 1.4e-07 31.1 6.9 1.4e-07 31.1 4.8 2.0 2 0 0 2 2 2 1 WW domain E1-E2_ATPase PF00122.15 EMD59179.1 - 1.1e-63 214.3 7.3 2.9e-63 213.0 5.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD59179.1 - 7.5e-22 78.8 0.0 2.3e-21 77.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD59179.1 - 1.6e-12 48.0 0.0 4.3e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD59179.1 - 1.4e-11 43.6 0.0 4e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD59179.1 - 0.0057 16.2 0.1 0.0057 16.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD59179.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Aldo_ket_red PF00248.16 EMD59180.1 - 1.8e-54 184.5 0.1 2.1e-54 184.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arylsulfotran_2 PF14269.1 EMD59180.1 - 0.088 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) DUF382 PF04037.8 EMD59181.1 - 1.8e-60 202.4 0.3 1.8e-60 202.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EMD59181.1 - 6.4e-24 83.0 6.6 1.5e-23 81.9 4.6 1.7 1 0 0 1 1 1 1 PSP CENP-B_dimeris PF09026.5 EMD59181.1 - 7 6.9 24.4 0.077 13.2 7.3 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpb2_6 PF00562.23 EMD59183.1 - 1.8e-116 389.0 0.0 3.1e-116 388.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMD59183.1 - 5e-52 175.7 0.9 1.8e-51 173.9 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMD59183.1 - 7.3e-31 107.0 0.5 1.6e-30 105.9 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMD59183.1 - 2.6e-29 101.2 2.1 3.1e-29 101.0 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EMD59183.1 - 3.3e-20 71.6 0.1 7.5e-20 70.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EMD59183.1 - 1.4e-18 66.4 0.0 4.1e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMD59183.1 - 4e-11 42.7 0.5 4e-11 42.7 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Mpt_N PF09176.6 EMD59183.1 - 0.017 14.9 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal F-box PF00646.28 EMD59184.1 - 0.00029 20.3 1.4 0.089 12.4 0.0 2.6 3 1 0 3 3 3 2 F-box domain F-box-like PF12937.2 EMD59184.1 - 0.0007 19.2 0.2 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.1 EMD59184.1 - 0.01 15.5 0.1 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 F-box-like domain FPN1 PF06963.7 EMD59185.1 - 0.17 10.2 0.6 0.26 9.6 0.4 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Tubulin PF00091.20 EMD59186.1 - 9.1e-70 234.8 0.0 1.3e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD59186.1 - 4.5e-50 168.9 0.1 8e-50 168.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMD59186.1 - 0.0017 17.8 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EMD59186.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Misat_Tub_SegII PF10644.4 EMD59186.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain WD40 PF00400.27 EMD59187.1 - 1.6e-22 78.4 7.3 1.1e-05 25.1 0.2 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat DUF3639 PF12341.3 EMD59187.1 - 7.3e-12 45.0 3.2 7.3e-12 45.0 2.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EMD59187.1 - 5.8e-05 22.0 0.1 0.00017 20.4 0.1 1.7 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 EMD59187.1 - 0.0036 17.0 0.7 0.88 9.2 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EMD59187.1 - 0.033 14.4 1.2 7.2 7.0 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain DUF3312 PF11768.3 EMD59187.1 - 0.075 11.2 0.0 0.18 10.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) MFS_1 PF07690.11 EMD59188.1 - 3.7e-33 114.7 31.5 3.7e-33 114.7 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59188.1 - 8.8e-08 31.1 13.9 8.8e-08 31.1 9.6 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMD59188.1 - 6.5e-07 27.9 1.4 1.1e-06 27.1 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMD59188.1 - 0.0031 15.9 5.3 0.0031 15.9 3.7 3.7 1 1 3 4 4 4 3 MFS/sugar transport protein DUF2012 PF09430.5 EMD59189.1 - 1.9e-26 92.3 0.0 2.5e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Tannase PF07519.6 EMD59189.1 - 0.066 11.9 0.2 0.33 9.6 0.1 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase LtrA PF06772.6 EMD59190.1 - 4.1e-17 62.1 18.1 7.2e-17 61.3 12.5 1.5 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) ATG16 PF08614.6 EMD59190.1 - 0.014 15.2 1.2 0.023 14.5 0.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 EMD59190.1 - 0.064 12.4 0.6 0.098 11.8 0.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Na_H_Exchanger PF00999.16 EMD59191.1 - 1.7e-43 148.5 22.9 2.2e-43 148.2 15.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Oxidored_q1_N PF00662.15 EMD59191.1 - 0.76 9.3 0.0 0.76 9.3 0.0 2.8 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Molybdopterin PF00384.17 EMD59192.1 - 2.8e-74 250.3 0.0 6.5e-72 242.6 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EMD59192.1 - 3.9e-19 68.2 0.1 1e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EMD59192.1 - 4.4e-19 67.4 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EMD59192.1 - 1.2e-13 50.9 0.0 3.5e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EMD59192.1 - 4.7e-08 32.6 0.7 4.7e-08 32.6 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EMD59192.1 - 0.00045 19.9 0.1 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EMD59192.1 - 0.11 12.1 1.0 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FA_desaturase PF00487.19 EMD59193.1 - 1.4e-26 93.4 16.9 2.3e-26 92.7 11.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMD59193.1 - 2e-06 27.8 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Mid1 PF12929.2 EMD59194.1 - 1.3e-145 485.4 6.1 1.5e-145 485.2 4.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EMD59194.1 - 0.47 10.8 4.5 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Fz domain Glyco_hydro_6 PF01341.12 EMD59195.1 - 1.5e-111 372.5 0.7 1.8e-111 372.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 RNA_pol_Rpc82 PF05645.8 EMD59197.1 - 1.1e-49 169.2 0.0 2.7e-46 158.1 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EMD59197.1 - 5.2e-22 77.4 2.1 1.2e-15 57.1 0.1 4.9 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EMD59197.1 - 0.00067 19.1 1.9 0.15 11.5 0.7 3.0 2 1 1 3 3 3 2 TFIIE alpha subunit TrmB PF01978.14 EMD59197.1 - 0.0008 19.0 0.2 16 5.2 0.0 4.3 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 EMD59197.1 - 0.024 14.9 0.1 19 5.6 0.0 3.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 EMD59197.1 - 0.099 12.5 0.5 1.5 8.7 0.0 3.1 4 0 0 4 4 4 0 B-block binding subunit of TFIIIC Peptidase_M16_C PF05193.16 EMD59198.1 - 1.2e-14 54.4 0.0 4.1e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMD59198.1 - 7.1e-12 45.3 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CBFD_NFYB_HMF PF00808.18 EMD59199.1 - 3.7e-05 23.6 0.0 5.7e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EMD59199.1 - 0.044 13.7 0.1 0.08 12.9 0.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component W Mak10 PF04112.8 EMD59200.1 - 6.2e-47 158.9 0.0 1.5e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EMD59201.1 - 5.2e-23 80.3 1.8 5.2e-23 80.3 1.2 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Proteasome PF00227.21 EMD59202.1 - 1.2e-48 164.9 0.0 1.6e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMD59202.1 - 6.5e-12 44.5 0.3 1.3e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EMD59202.1 - 0.0077 15.8 0.7 2.4 7.8 0.0 3.1 2 1 1 3 3 3 1 Flagellar hook-length control protein FliK DUF1403 PF07183.6 EMD59202.1 - 0.04 13.2 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Vps55 PF04133.9 EMD59203.1 - 1.4e-42 144.2 5.8 1.6e-42 144.0 4.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF3329 PF11808.3 EMD59203.1 - 0.34 11.0 1.7 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) EpsG PF14897.1 EMD59203.1 - 0.5 9.2 5.8 1.1 8.1 4.0 1.5 1 1 0 1 1 1 0 EpsG family Nramp PF01566.13 EMD59203.1 - 0.8 8.4 10.3 2.1 7.0 2.3 2.1 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein UPF0220 PF05255.6 EMD59204.1 - 7.8e-68 226.9 1.9 8.7e-68 226.7 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4376 PF14301.1 EMD59205.1 - 0.42 10.7 5.9 6 7.0 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) DUF3840 PF12944.2 EMD59205.1 - 0.76 9.6 5.3 0.93 9.3 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3840) Abhydrolase_6 PF12697.2 EMD59206.1 - 2.8e-11 43.7 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD59206.1 - 1.9e-08 34.1 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD59206.1 - 0.0035 17.1 0.0 0.0066 16.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cohesin_load PF10345.4 EMD59207.1 - 4.3e-108 362.1 0.0 5.8e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Cohesin loading factor zf-CCHC PF00098.18 EMD59208.1 - 0.012 15.5 2.9 0.02 14.7 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle ADIP PF11559.3 EMD59208.1 - 0.094 12.6 3.3 0.12 12.2 2.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DOR PF14839.1 EMD59208.1 - 0.35 10.6 7.4 0.55 9.9 5.0 1.4 1 1 0 1 1 1 0 DOR family HemY_N PF07219.8 EMD59208.1 - 0.43 10.1 4.6 0.59 9.6 3.2 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Trypan_PARP PF05887.6 EMD59209.1 - 2.6e-11 43.5 179.7 0.00014 21.6 7.8 4.2 2 1 2 4 4 4 4 Procyclic acidic repetitive protein (PARP) PAN_2 PF08276.6 EMD59209.1 - 0.0017 18.1 3.7 0.053 13.3 0.1 2.5 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.1 EMD59209.1 - 0.0051 16.4 0.8 0.0051 16.4 0.5 3.2 3 1 0 3 3 3 2 PAN domain PAN_3 PF08277.7 EMD59209.1 - 0.0063 16.1 6.3 0.056 13.0 0.2 2.4 2 0 0 2 2 2 2 PAN-like domain LCM PF04072.9 EMD59209.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase JmjC PF02373.17 EMD59211.1 - 4.8e-37 126.6 0.5 1.1e-36 125.5 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EMD59211.1 - 4.9e-19 68.3 2.3 9.1e-19 67.4 1.6 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMD59211.1 - 2.3e-18 66.0 3.2 4.3e-18 65.2 2.2 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EMD59211.1 - 1.7e-14 52.9 1.1 4.5e-14 51.6 0.7 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EMD59211.1 - 1.4 8.6 8.3 0.23 11.1 2.0 2.2 2 0 0 2 2 2 0 PHD-finger Atg14 PF10186.4 EMD59212.1 - 0.13 11.1 10.6 0.19 10.6 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2220 PF09983.4 EMD59212.1 - 0.31 10.1 2.9 0.58 9.3 2.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) F-box PF00646.28 EMD59213.1 - 2.3e-07 30.2 2.8 2.3e-07 30.2 1.9 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMD59213.1 - 4.6e-07 29.4 1.3 8.9e-07 28.5 0.9 1.5 1 0 0 1 1 1 1 F-box-like SAE2 PF08573.5 EMD59214.1 - 4.6e-28 97.7 0.1 4.6e-28 97.7 0.1 4.8 3 2 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-RING_2 PF13639.1 EMD59215.1 - 2.4e-12 46.4 9.3 4.3e-12 45.6 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD59215.1 - 3.7e-08 33.3 6.0 7.1e-08 32.4 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD59215.1 - 1.7e-07 30.7 8.2 4.2e-07 29.5 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD59215.1 - 1.8e-06 27.8 10.1 5.2e-06 26.3 7.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD59215.1 - 3.8e-06 26.6 3.6 7.2e-06 25.7 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMD59215.1 - 9.5e-06 25.2 10.2 2.2e-05 24.0 7.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD59215.1 - 1.1e-05 24.9 9.4 2.3e-05 23.9 6.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 EMD59215.1 - 0.0015 18.3 1.0 0.0035 17.1 0.7 1.6 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EMD59215.1 - 0.0047 16.6 5.5 0.022 14.4 1.2 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMD59215.1 - 0.005 16.6 5.1 0.005 16.6 3.5 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMD59215.1 - 0.011 15.2 5.0 0.011 15.2 3.5 1.9 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMD59215.1 - 0.027 14.2 0.5 0.027 14.2 0.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 EMD59215.1 - 0.034 14.1 9.0 0.18 11.7 6.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain TLP-20 PF06088.6 EMD59215.1 - 0.065 12.8 1.5 0.1 12.2 1.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Radial_spoke PF04712.7 EMD59215.1 - 0.07 11.8 9.6 0.095 11.4 6.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RNase_H2_suC PF08615.6 EMD59215.1 - 0.1 12.4 1.3 0.31 10.8 0.9 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.1 EMD59215.1 - 0.24 11.7 20.0 1.5 9.1 8.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EMD59215.1 - 0.26 9.1 17.9 0.35 8.7 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 EMD59215.1 - 0.29 9.9 9.8 0.42 9.4 6.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 EMD59215.1 - 0.31 10.0 12.6 0.42 9.6 8.8 1.1 1 0 0 1 1 1 0 BUD22 RINGv PF12906.2 EMD59215.1 - 0.5 10.4 9.7 0.33 11.0 5.2 1.9 2 1 0 2 2 1 0 RING-variant domain zf-RING_4 PF14570.1 EMD59215.1 - 0.55 9.8 8.9 2.3 7.8 6.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EMD59215.1 - 0.7 9.4 5.5 0.34 10.4 1.8 1.9 2 0 0 2 2 2 0 P-11 zinc finger Sporozoite_P67 PF05642.6 EMD59215.1 - 0.75 7.5 4.2 1 7.1 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prok-RING_4 PF14447.1 EMD59215.1 - 1.7 8.2 8.8 0.48 9.9 2.9 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 BSP_II PF05432.6 EMD59215.1 - 3.5 6.8 17.7 0.2 10.9 5.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EMD59215.1 - 4.4 5.2 15.1 5.6 4.8 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EMD59215.1 - 5.1 6.6 26.5 11 5.4 0.2 2.2 2 0 0 2 2 2 0 Nucleoplasmin MARVEL PF01284.18 EMD59217.1 - 1.5e-14 54.0 13.1 2e-14 53.6 9.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3624 PF12292.3 EMD59217.1 - 0.31 11.4 7.1 5 7.6 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Polysacc_deac_1 PF01522.16 EMD59219.1 - 1.6e-27 95.6 0.1 3.4e-27 94.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMD59219.1 - 5.3e-11 42.3 58.7 5.2e-08 32.7 12.2 3.8 3 1 0 3 3 3 2 Chitin recognition protein Mif2_N PF15624.1 EMD59222.1 - 5.4e-34 117.7 2.5 5.4e-34 117.7 1.7 3.8 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EMD59222.1 - 1.3e-25 89.1 0.3 2.2e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EMD59222.1 - 0.0093 15.4 0.2 0.02 14.4 0.1 1.4 1 0 0 1 1 1 1 Cupin domain O-antigen_lig PF13425.1 EMD59224.1 - 0.0035 17.3 3.0 0.0035 17.3 2.1 2.3 3 0 0 3 3 3 1 O-antigen ligase like membrane protein DUF4239 PF14023.1 EMD59224.1 - 8.7 5.6 9.1 13 5.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Myb_DNA-binding PF00249.26 EMD59225.1 - 2.3e-11 43.5 2.3 2.9e-08 33.6 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD59225.1 - 1.2e-07 31.7 4.3 4.9e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EMD59227.1 - 2e-24 85.0 0.1 2.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EMD59227.1 - 9.1e-21 73.9 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EMD59227.1 - 0.00028 20.2 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Amidohydro_4 PF13147.1 EMD59228.1 - 1.2e-24 87.8 0.0 1.5e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMD59228.1 - 1.8e-15 56.4 0.3 5.4e-15 54.9 0.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD59228.1 - 8e-10 38.8 0.2 9.3e-06 25.5 0.1 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EMD59228.1 - 1.5e-06 27.6 0.2 0.032 13.4 0.1 2.6 2 1 1 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EMD59228.1 - 0.033 14.3 0.6 0.062 13.4 0.4 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Peptidase_M20 PF01546.23 EMD59229.1 - 4e-28 98.2 0.1 5.4e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD59229.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMD59229.1 - 0.0006 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Glyco_hydro_61 PF03443.9 EMD59230.1 - 7e-52 176.3 0.0 8.5e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_85 PF03644.8 EMD59232.1 - 4.7e-79 265.7 0.0 6.7e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DHH PF01368.15 EMD59232.1 - 4.4e-05 23.1 0.0 9.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 DHH family ER_lumen_recept PF00810.13 EMD59233.1 - 1.1e-54 184.9 9.9 1.7e-54 184.3 6.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EMD59233.1 - 0.95 9.0 16.9 1 8.9 0.2 4.5 3 1 2 5 5 5 0 PQ loop repeat BC10 PF06726.7 EMD59234.1 - 3.1e-12 46.3 9.7 4.5e-12 45.8 6.7 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Peptidase_M1 PF01433.15 EMD59235.1 - 2.8e-130 434.9 0.4 4.3e-130 434.2 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EMD59235.1 - 1.3e-75 254.6 0.0 2.1e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMD59235.1 - 4.3e-22 78.5 3.4 5.5e-22 78.1 0.5 2.3 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EMD59235.1 - 0.15 11.7 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 FAD_binding_3 PF01494.14 EMD59236.1 - 3.1e-57 194.2 0.0 1.3e-55 188.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD59236.1 - 9e-06 24.8 0.0 1.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD59236.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMD59236.1 - 1.1e-05 24.2 0.0 1.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 EMD59236.1 - 4e-05 22.8 0.0 7.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMD59236.1 - 0.00028 20.8 0.2 0.00099 19.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD59236.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD59236.1 - 0.0016 16.9 0.0 0.012 14.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMD59236.1 - 0.0032 16.6 0.2 0.068 12.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD59236.1 - 0.0057 16.7 0.0 0.014 15.4 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD59236.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMD59236.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EMD59236.1 - 0.12 12.3 0.0 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DUF3818 PF12825.2 EMD59237.1 - 8.1e-44 149.6 1.8 6.4e-31 107.2 0.1 3.5 3 1 1 4 4 4 3 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMD59237.1 - 5.7e-35 119.9 0.0 1.6e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 PX-associated Fungal_trans_2 PF11951.3 EMD59239.1 - 6.4e-07 28.3 1.2 1.8e-06 26.8 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 EMD59241.1 - 3e-37 128.0 0.2 4e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD59241.1 - 1.3e-14 53.4 0.2 2.4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD59241.1 - 4.6e-14 52.7 0.0 7.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD59241.1 - 3.5e-09 37.2 0.1 2.1e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DEAD_2 PF06733.10 EMD59241.1 - 0.079 12.3 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 HpaB_N PF11794.3 EMD59241.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PAM2 PF07145.10 EMD59242.1 - 0.2 11.2 1.2 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Glyco_hydro_10 PF00331.15 EMD59243.1 - 2.1e-97 326.0 0.1 2.4e-97 325.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.13 EMD59243.1 - 0.002 16.3 0.2 0.015 13.5 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 1 AP_endonuc_2 PF01261.19 EMD59243.1 - 0.0029 16.9 0.0 0.048 12.9 0.0 2.1 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel SSI PF00720.12 EMD59244.1 - 0.033 14.0 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Subtilisin inhibitor-like GMC_oxred_N PF00732.14 EMD59246.1 - 2.1e-53 181.4 0.0 2.8e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD59246.1 - 2.9e-34 118.4 0.0 5.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMD59246.1 - 0.0001 22.2 0.1 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD59246.1 - 0.00014 20.8 0.1 0.0023 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMD59246.1 - 0.00043 19.2 0.1 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD59246.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD59246.1 - 0.019 15.0 0.1 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD59246.1 - 0.099 11.7 0.1 0.27 10.2 0.0 1.7 1 1 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD59246.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EMD59246.1 - 0.19 10.7 0.4 0.4 9.6 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain TPR_11 PF13414.1 EMD59248.1 - 0.058 13.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EMD59248.1 - 0.12 13.0 0.8 0.4 11.4 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EMD59249.1 - 1.5e-29 102.9 0.0 1e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD59249.1 - 2.6e-12 46.3 0.0 4.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.27 EMD59250.1 - 3.3e-25 86.9 13.3 6.9e-05 22.5 0.8 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMD59250.1 - 0.00015 20.6 1.0 0.63 8.7 0.0 3.7 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EMD59250.1 - 0.00022 19.5 0.4 0.052 11.6 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DUF771 PF05595.6 EMD59250.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF771) XRCC4 PF06632.7 EMD59252.1 - 0.0067 15.3 13.8 0.018 13.9 9.5 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SPX PF03105.14 EMD59252.1 - 0.34 10.6 6.3 0.45 10.2 4.4 1.3 1 0 0 1 1 1 0 SPX domain DUF913 PF06025.7 EMD59252.1 - 0.67 8.6 5.5 1 8.0 3.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.9 EMD59252.1 - 2.2 7.7 16.3 1.9 7.9 9.1 2.3 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Hid1 PF12722.2 EMD59252.1 - 4.9 4.7 5.8 5.6 4.5 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pur_DNA_glyco PF02245.11 EMD59254.1 - 0.13 11.4 0.2 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) BTB PF00651.26 EMD59256.1 - 0.091 12.7 0.1 0.25 11.3 0.0 1.9 2 1 0 2 2 2 0 BTB/POZ domain 2-Hacid_dh_C PF02826.14 EMD59258.1 - 5.5e-51 172.2 0.0 9.1e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD59258.1 - 1.1e-15 57.2 0.0 1.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD59258.1 - 0.00095 19.0 0.0 0.0026 17.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sarcoglycan_2 PF05510.8 EMD59259.1 - 0.086 11.1 0.1 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon FH2 PF02181.18 EMD59260.1 - 6.4e-80 268.7 5.2 6.4e-80 268.7 3.6 1.9 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EMD59260.1 - 6.3e-67 224.5 2.2 7.1e-67 224.4 0.0 2.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EMD59260.1 - 2.3e-51 174.0 2.3 2.3e-51 174.0 1.6 3.0 2 1 1 3 3 3 1 Diaphanous FH3 Domain peroxidase PF00141.18 EMD59262.1 - 1.1e-27 97.0 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EMD59262.1 - 0.00015 21.5 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Amidohydro_2 PF04909.9 EMD59263.1 - 6.2e-15 55.4 0.2 7.5e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase HATPase_c PF02518.21 EMD59264.1 - 1.4e-22 79.4 0.0 3.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD59264.1 - 7.2e-19 67.8 0.0 2.3e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMD59264.1 - 2.7e-13 49.6 0.0 1.2e-12 47.5 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EMD59264.1 - 1.4e-06 28.5 0.0 7.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 EMD59264.1 - 0.0023 18.0 0.0 0.088 12.9 0.0 3.1 3 1 0 3 3 3 1 GAF domain HATPase_c_5 PF14501.1 EMD59264.1 - 0.037 13.7 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 GHKL domain DUF2011 PF09428.5 EMD59265.1 - 5.7e-27 94.1 12.2 1.1e-26 93.2 8.5 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF3340 PF11818.3 EMD59265.1 - 0.00088 19.2 6.6 0.0014 18.5 4.6 1.3 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) IpaD PF06511.6 EMD59265.1 - 2.1 7.2 6.9 3.8 6.4 4.8 1.3 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD NPR3 PF03666.8 EMD59265.1 - 9.7 4.5 10.0 17 3.7 6.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HET PF06985.6 EMD59266.1 - 2.3e-07 31.0 0.1 0.0014 18.8 0.0 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DNA_III_psi PF03603.8 EMD59267.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III psi subunit Mso1_Sec1_bdg PF14475.1 EMD59268.1 - 1.9e-17 62.3 0.1 3.4e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.13 EMD59269.1 - 4.9e-39 134.0 1.9 9.5e-39 133.0 1.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EMD59269.1 - 6.1e-11 42.0 0.0 0.00037 19.8 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function (DUF3548) MerB PF03243.10 EMD59270.1 - 0.14 11.9 0.0 24 4.7 0.0 2.5 2 0 0 2 2 2 0 Alkylmercury lyase TPR_12 PF13424.1 EMD59271.1 - 2.9e-41 139.2 27.1 6.3e-16 58.0 2.3 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMD59271.1 - 1.4e-27 94.7 3.0 1.1e-07 31.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD59271.1 - 2.7e-10 39.2 8.1 0.00076 19.0 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD59271.1 - 2.7e-09 36.2 8.6 0.01 15.6 0.3 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD59271.1 - 1.7e-08 33.7 10.5 0.0026 17.2 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD59271.1 - 1.5e-06 28.2 0.8 2.5 8.9 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD59271.1 - 3.3e-06 26.1 0.1 7.3e-05 21.7 0.0 2.4 1 1 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EMD59271.1 - 1.1e-05 25.9 1.3 0.085 13.5 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD59271.1 - 2.5e-05 23.8 11.2 0.00095 18.7 2.4 4.0 1 1 4 5 5 5 3 TPR repeat Apc3 PF12895.2 EMD59271.1 - 0.00021 21.3 7.3 0.033 14.3 1.9 3.2 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMD59271.1 - 0.00045 20.4 5.7 0.11 12.8 1.3 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMD59271.1 - 0.039 14.4 3.1 13 6.4 0.2 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EMD59271.1 - 0.13 12.3 0.2 12 6.1 0.0 3.5 2 0 0 2 2 2 0 PPR repeat Rab5-bind PF09311.6 EMD59271.1 - 0.53 10.1 8.4 0.053 13.4 2.3 1.9 2 1 0 2 2 1 0 Rabaptin-like protein TPR_3 PF07720.7 EMD59271.1 - 2 8.2 7.6 0.28 11.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD59271.1 - 4.8 7.1 6.8 3.5 7.6 0.6 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat HET PF06985.6 EMD59272.1 - 3.5e-12 46.6 12.0 5.4e-09 36.3 5.1 3.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EMD59274.1 - 5.1e-16 59.0 1.0 5.1e-16 59.0 0.7 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) W2 PF02020.13 EMD59274.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon UCH PF00443.24 EMD59275.1 - 3.5e-28 98.4 0.0 4.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD59275.1 - 5.7e-13 48.9 0.0 9.9e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase COX4 PF02936.9 EMD59276.1 - 4.5e-43 146.3 0.1 5.8e-43 146.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV MgtE_N PF03448.12 EMD59276.1 - 0.066 13.5 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain DUF3106 PF11304.3 EMD59276.1 - 0.44 10.9 6.0 0.12 12.8 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Gp_dh_C PF02800.15 EMD59277.1 - 6.5e-75 249.8 0.1 9.7e-75 249.2 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EMD59277.1 - 2.2e-60 203.0 0.1 3.7e-60 202.2 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EMD59277.1 - 0.005 16.7 0.1 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Hist_deacetyl PF00850.14 EMD59279.1 - 5.9e-99 331.2 0.7 1.1e-98 330.3 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EMD59279.1 - 1e-46 158.5 0.4 3.3e-46 156.9 0.2 1.8 2 0 0 2 2 2 1 Arb2 domain Cyclin PF08613.6 EMD59281.1 - 3.4e-27 95.6 0.0 7.3e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMD59281.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EMD59283.1 - 1.5e-14 53.1 7.4 0.0021 17.8 0.0 8.4 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EMD59283.1 - 0.017 14.2 0.4 9.1 5.2 0.0 4.1 5 0 0 5 5 5 0 V-ATPase subunit H HEAT_EZ PF13513.1 EMD59283.1 - 0.025 15.0 11.0 0.087 13.3 0.1 6.1 7 0 0 7 7 7 0 HEAT-like repeat MethyTransf_Reg PF10119.4 EMD59283.1 - 0.026 14.9 0.1 0.07 13.6 0.1 1.7 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain NusB PF01029.13 EMD59283.1 - 0.093 12.7 0.2 7.1 6.6 0.0 2.8 2 0 0 2 2 2 0 NusB family HEAT PF02985.17 EMD59283.1 - 0.48 10.6 15.9 2.9 8.1 0.0 6.7 8 1 0 8 8 8 0 HEAT repeat Coprogen_oxidas PF01218.13 EMD59284.1 - 6e-134 445.2 0.1 7.1e-134 444.9 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EMD59285.1 - 2.2e-51 172.1 0.3 2.6e-51 171.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMD59285.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 EMD59286.1 - 8.2e-05 22.0 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DNA_pol3_gamma3 PF12169.3 EMD59286.1 - 0.053 13.2 0.0 0.053 13.2 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Shadoo PF14999.1 EMD59288.1 - 0.54 10.1 7.8 0.62 9.9 5.4 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF3628 PF12300.3 EMD59288.1 - 1.7 8.6 11.6 2.4 8.1 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Mucin PF01456.12 EMD59289.1 - 0.049 13.4 18.9 0.064 13.0 13.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Adeno_PIX PF03955.9 EMD59289.1 - 0.24 11.9 3.2 0.37 11.3 2.2 1.4 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) ATP-synt_ab PF00006.20 EMD59290.1 - 4.7e-60 202.7 0.0 7.3e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMD59290.1 - 7.4e-26 90.8 0.5 1.7e-25 89.6 0.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMD59290.1 - 2.2e-23 82.2 1.6 5.1e-23 81.0 0.7 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EMD59290.1 - 0.0036 16.7 0.4 0.037 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EMD59290.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EMD59290.1 - 0.013 15.2 0.2 1.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EMD59290.1 - 0.013 14.7 0.2 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EMD59290.1 - 0.02 14.5 0.3 0.051 13.2 0.1 1.8 2 1 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EMD59290.1 - 0.023 14.7 0.6 0.31 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EMD59290.1 - 0.027 14.6 0.4 1.6 8.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMD59290.1 - 0.031 13.4 0.2 0.064 12.3 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EMD59290.1 - 0.033 14.3 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMD59290.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF463 PF04317.7 EMD59290.1 - 0.09 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 NB-ARC PF00931.17 EMD59290.1 - 0.13 11.0 0.7 0.51 9.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Omega_Repress PF07764.6 EMD59291.1 - 0.083 13.2 0.4 0.23 11.8 0.3 1.7 2 0 0 2 2 2 0 Omega Transcriptional Repressor VHS PF00790.14 EMD59292.1 - 0.00087 18.9 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-RING_2 PF13639.1 EMD59292.1 - 0.014 15.2 0.7 0.03 14.1 0.1 1.8 2 0 0 2 2 2 0 Ring finger domain CTD_bind PF04818.8 EMD59292.1 - 0.093 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. zf-C2HC_2 PF13913.1 EMD59292.1 - 0.16 11.6 4.1 3.8 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 EMD59292.1 - 0.35 10.4 1.0 0.98 8.9 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 CFIA_Pcf11 PF11526.3 EMD59292.1 - 0.35 11.0 2.3 3.4 7.8 1.6 2.3 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-C2H2 PF00096.21 EMD59292.1 - 0.95 9.9 2.4 22 5.6 0.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Med26 PF08711.6 EMD59293.1 - 1.5e-12 46.7 0.0 3.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Iron_permease PF04120.7 EMD59293.1 - 0.013 15.1 2.2 0.013 15.1 1.5 1.7 2 0 0 2 2 2 0 Low affinity iron permease Pectate_lyase_3 PF12708.2 EMD59294.1 - 9e-78 261.4 22.8 1e-61 208.9 8.4 3.4 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMD59294.1 - 1.7e-05 24.1 1.4 0.12 11.8 0.1 3.1 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Tom5 PF10642.4 EMD59295.1 - 6.7e-11 41.6 1.1 8.3e-11 41.3 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EMD59296.1 - 3.6e-41 140.1 1.4 3.6e-41 140.1 0.9 2.8 3 1 1 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EMD59296.1 - 1.7e-16 60.4 44.2 3.5e-16 59.4 30.6 1.5 1 0 0 1 1 1 1 Nucleoporin FG repeat region Fmp27_WPPW PF10359.4 EMD59296.1 - 0.072 11.4 8.2 0.016 13.6 2.3 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3829 PF12889.2 EMD59296.1 - 1.2 8.2 7.9 1.8 7.6 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF342 PF03961.8 EMD59296.1 - 3.6 5.9 7.3 9.4 4.5 4.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CHCH PF06747.8 EMD59297.1 - 1.7e-06 27.7 5.8 1.7e-06 27.7 4.0 2.7 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EMD59297.1 - 0.18 11.6 14.3 0.86 9.4 3.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMD59297.1 - 0.25 11.3 10.6 0.29 11.2 4.0 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Apc15p PF05841.6 EMD59298.1 - 2.2e-17 63.9 0.9 2.2e-17 63.9 0.6 3.1 2 1 1 3 3 3 1 Apc15p protein AAA_2 PF07724.9 EMD59303.1 - 6.6e-39 133.5 0.0 1.7e-38 132.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMD59303.1 - 1.6e-15 57.4 0.0 6.5e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMD59303.1 - 3.8e-09 36.3 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EMD59303.1 - 1.4e-05 24.8 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD59303.1 - 3.6e-05 23.8 0.3 0.00064 19.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD59303.1 - 4.2e-05 24.3 0.1 0.00011 22.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMD59303.1 - 0.00033 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMD59303.1 - 0.00039 20.3 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMD59303.1 - 0.00096 18.6 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EMD59303.1 - 0.0049 16.3 0.2 0.034 13.6 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EMD59303.1 - 0.011 15.1 0.1 0.044 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EMD59303.1 - 0.017 15.4 1.1 0.042 14.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMD59303.1 - 0.018 14.5 0.1 0.49 9.8 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 EMD59303.1 - 0.028 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EMD59303.1 - 0.03 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EMD59303.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.0 3 1 1 4 4 4 0 AAA ATPase domain RuvB_N PF05496.7 EMD59303.1 - 0.053 12.5 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IPT PF01745.11 EMD59303.1 - 0.068 12.3 0.1 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase KaiC PF06745.8 EMD59303.1 - 0.075 12.1 0.0 0.23 10.5 0.0 1.8 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 EMD59303.1 - 0.21 10.7 2.2 0.37 9.9 0.1 2.2 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Alpha-amylase_C PF02806.13 EMD59304.1 - 3.1e-26 91.3 0.1 7.2e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EMD59304.1 - 6.9e-16 58.5 0.2 1.9e-12 47.1 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EMD59304.1 - 7.9e-15 54.6 0.4 2e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) tRNA-synt_1 PF00133.17 EMD59305.1 - 2.3e-51 174.5 0.0 7.4e-22 77.0 0.2 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) Suc_Fer-like PF06999.7 EMD59305.1 - 2.3e-48 165.2 0.0 4.1e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1_2 PF13603.1 EMD59305.1 - 3.6e-40 137.2 0.0 6e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EMD59305.1 - 1.1e-27 96.6 2.7 8.9e-22 77.2 0.0 4.6 5 1 0 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMD59305.1 - 8.9e-11 41.7 0.1 1.8e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EMD59305.1 - 0.0025 16.6 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EMD59305.1 - 0.038 13.1 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain AA_permease_2 PF13520.1 EMD59306.1 - 3.4e-65 220.2 37.3 6.4e-65 219.3 26.0 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD59306.1 - 1.2e-32 112.9 24.2 1.2e-32 112.9 16.8 2.2 2 1 0 2 2 2 1 Amino acid permease Cyt_c_ox_IV PF12270.3 EMD59307.1 - 0.015 15.0 1.7 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF308 PF03729.8 EMD59307.1 - 0.025 14.5 0.8 0.025 14.5 0.5 2.6 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF1980 PF09323.5 EMD59307.1 - 0.067 12.9 0.4 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) BioY PF02632.9 EMD59307.1 - 0.59 9.7 7.1 0.51 9.9 3.5 1.8 1 1 1 2 2 2 0 BioY family DUF2231 PF09990.4 EMD59307.1 - 4.2 7.7 9.4 16 5.9 2.8 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Aminotran_5 PF00266.14 EMD59309.1 - 5.5e-28 97.7 0.0 2.1e-16 59.6 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EMD59310.1 - 1.4e-70 238.0 0.6 6.1e-42 143.6 0.2 3.1 1 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMD59310.1 - 1.7e-25 89.5 0.0 3.4e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Mito_carr PF00153.22 EMD59312.1 - 1.9e-30 104.4 1.4 2.9e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EMD59313.1 - 2.1e-65 219.0 0.6 2.4e-65 218.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD59313.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD59313.1 - 2e-16 59.7 0.1 2.3e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD59313.1 - 2.2e-05 23.9 0.2 4.5e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD59313.1 - 2.4e-05 23.5 0.1 3.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD59313.1 - 9.4e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EMD59313.1 - 0.00025 21.2 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EMD59313.1 - 0.00062 19.0 0.0 0.00089 18.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMD59313.1 - 0.00093 18.5 0.0 0.0059 15.9 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EMD59313.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD59313.1 - 0.011 15.7 0.1 0.033 14.1 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EMD59313.1 - 0.015 14.5 0.0 0.032 13.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMD59313.1 - 0.033 14.0 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD59313.1 - 0.036 13.5 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMD59313.1 - 0.047 13.4 0.1 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.11 EMD59314.1 - 3.5e-31 108.2 33.1 6.6e-24 84.2 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD59314.1 - 2.9e-08 33.3 2.1 2.9e-05 23.7 0.2 2.9 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.8 EMD59314.1 - 0.00014 20.2 1.0 0.00014 20.2 0.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMD59314.1 - 0.00035 19.0 15.1 0.0027 16.1 3.4 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EMD59314.1 - 0.00068 18.3 16.2 0.0037 15.9 2.1 3.2 2 1 1 4 4 4 2 Sugar (and other) transporter OATP PF03137.15 EMD59314.1 - 0.081 10.9 2.0 4.6 5.1 0.1 3.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EMD59315.1 - 4.9e-74 249.5 23.5 5.6e-74 249.3 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59315.1 - 2.3e-14 52.9 44.5 9.8e-09 34.3 5.3 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily EF-hand_4 PF12763.2 EMD59316.1 - 6.7e-35 118.9 0.0 1e-13 50.9 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EMD59316.1 - 5.4e-10 39.2 0.0 0.0011 19.0 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain pair UBA PF00627.26 EMD59316.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.4 EMD59316.1 - 4.5e-06 25.2 10.6 4.5e-06 25.2 7.3 2.4 2 0 0 2 2 2 1 Transmembrane protein EF-hand_1 PF00036.27 EMD59316.1 - 2.1e-05 23.4 0.0 0.4 10.0 0.0 4.7 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 EMD59316.1 - 0.0006 19.3 0.0 1.9 8.2 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair Atg14 PF10186.4 EMD59316.1 - 0.013 14.5 32.2 0.033 13.1 9.2 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EMD59316.1 - 0.021 14.6 29.2 0.01 15.7 6.8 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.7 EMD59316.1 - 0.03 12.5 21.6 0.038 12.1 14.1 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA BicD PF09730.4 EMD59316.1 - 0.032 12.5 27.9 0.3 9.4 19.0 2.1 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.7 EMD59316.1 - 0.039 13.7 28.7 0.054 13.2 10.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EMD59316.1 - 0.087 12.7 34.1 0.058 13.2 10.4 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 EMD59316.1 - 0.1 11.0 20.9 0.15 10.4 14.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 EMD59316.1 - 0.21 11.1 30.1 0.61 9.6 12.4 2.3 1 1 1 2 2 2 0 IncA protein MAD PF05557.8 EMD59316.1 - 0.63 8.0 26.8 1.1 7.2 18.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein ATG16 PF08614.6 EMD59316.1 - 0.77 9.5 29.9 0.26 11.0 8.1 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMD59316.1 - 0.81 8.8 12.0 0.28 10.3 1.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EMD59316.1 - 1 8.7 28.3 0.68 9.3 10.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein Myosin_tail_1 PF01576.14 EMD59316.1 - 1.3 6.7 28.9 0.36 8.5 15.8 1.9 1 1 1 2 2 2 0 Myosin tail CALCOCO1 PF07888.6 EMD59316.1 - 1.5 6.9 21.8 4.7 5.3 15.1 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.5 EMD59316.1 - 1.8 8.6 24.7 0.28 11.3 8.7 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1192 PF06698.6 EMD59316.1 - 2.6 7.9 6.6 0.21 11.4 0.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) CENP-Q PF13094.1 EMD59316.1 - 2.8 7.9 30.4 0.088 12.8 10.4 3.1 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.15 EMD59316.1 - 3.4 7.4 24.3 1.7 8.4 0.7 4.2 2 2 0 2 2 2 0 Prefoldin subunit DUF2968 PF11180.3 EMD59316.1 - 3.6 6.9 28.3 4.4 6.6 10.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3450 PF11932.3 EMD59316.1 - 4 6.6 28.1 6.4 5.9 6.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 EMD59316.1 - 4.7 6.3 29.8 3.6 6.7 10.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EMD59316.1 - 5.9 6.6 18.7 4.9 6.8 5.4 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF869 PF05911.6 EMD59316.1 - 6 4.9 26.0 1.1 7.4 8.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 EMD59316.1 - 8.2 4.7 22.1 15 3.9 15.3 1.3 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.16 EMD59318.1 - 4.4e-24 85.2 0.0 6.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD59318.1 - 2.2e-09 36.6 0.0 3.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMD59318.1 - 1.3e-07 30.6 0.0 5.2e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD59318.1 - 1.4e-07 30.6 0.0 7.1e-07 28.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMD59318.1 - 6.2e-07 28.5 0.1 0.00091 18.2 0.2 2.7 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD59318.1 - 7.7e-07 29.2 0.0 2.7e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD59318.1 - 0.14 11.4 0.0 0.8 8.9 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Vps51 PF08700.6 EMD59319.1 - 1.7e-14 53.3 0.0 9.5e-14 51.0 0.0 2.4 1 0 0 1 1 1 1 Vps51/Vps67 Mer2 PF09074.5 EMD59319.1 - 0.0031 17.4 2.5 0.0049 16.8 0.1 2.5 3 0 0 3 3 3 1 Mer2 GCIP PF13324.1 EMD59319.1 - 0.026 13.7 0.4 0.026 13.7 0.3 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Chorismate_bind PF00425.13 EMD59320.1 - 5.5e-63 212.6 0.3 9.3e-36 123.4 0.1 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 EMD59320.1 - 5.7e-28 97.6 0.0 1.9e-27 95.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EMD59320.1 - 1.1e-15 57.8 0.0 2.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EMD59320.1 - 3.1e-06 26.7 0.6 2.8e-05 23.6 0.4 2.1 1 1 0 1 1 1 1 Peptidase C26 FAD_binding_6 PF00970.19 EMD59321.1 - 4e-09 36.4 0.0 1.4e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD59321.1 - 1.8e-07 31.7 0.1 5.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 EMD59322.1 - 1.2e-38 132.7 44.0 2.4e-37 128.5 30.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59322.1 - 1.4 7.3 32.4 0.35 9.3 10.9 3.2 1 1 1 3 3 3 0 Sugar (and other) transporter HLH PF00010.21 EMD59323.1 - 6.3e-06 25.7 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 EMD59323.1 - 1.2 7.3 15.9 1.4 7.0 11.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_YtfJ PF09579.5 EMD59323.1 - 3.9 7.3 6.5 51 3.8 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) MCPVI PF02993.9 EMD59323.1 - 4.8 7.2 14.0 0.12 12.5 5.2 1.6 2 0 0 2 2 2 0 Minor capsid protein VI MFS_1 PF07690.11 EMD59324.1 - 1e-07 31.0 24.2 4.6e-07 28.8 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2273 PF10031.4 EMD59324.1 - 4.2 7.0 7.6 0.28 10.8 0.4 2.9 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) cwf21 PF08312.7 EMD59325.1 - 4.1e-16 58.5 12.4 4.1e-16 58.5 8.6 2.7 2 1 0 2 2 2 1 cwf21 domain Trans_reg_C PF00486.23 EMD59325.1 - 0.0094 15.8 1.2 0.19 11.6 0.0 2.7 1 1 1 2 2 2 2 Transcriptional regulatory protein, C terminal D123 PF07065.9 EMD59326.1 - 1.3e-100 336.3 0.0 2.3e-97 325.7 0.0 2.2 1 1 1 2 2 2 2 D123 Zn_clus PF00172.13 EMD59328.1 - 3.8e-07 29.8 10.2 7.8e-07 28.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD59328.1 - 4.2e-05 22.3 0.9 5.8e-05 21.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_F17 PF04767.7 EMD59328.1 - 0.26 11.5 2.8 0.6 10.4 1.9 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein AA_permease PF00324.16 EMD59329.1 - 1.8e-123 412.3 45.3 2.3e-123 412.0 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD59329.1 - 4.8e-34 117.6 51.4 5.8e-34 117.3 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3129 PF11327.3 EMD59330.1 - 8.3e-73 244.1 8.4 1.2e-72 243.5 5.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) HET PF06985.6 EMD59332.1 - 1.1e-08 35.2 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 EMD59333.1 - 7.1e-29 100.4 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD59333.1 - 1.7e-09 37.4 10.9 2.6e-09 36.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 EMD59335.1 - 2.4e-51 174.5 2.2 3e-51 174.1 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) VHL PF01847.11 EMD59335.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein GPAT_N PF14829.1 EMD59335.1 - 0.16 11.6 0.4 15 5.3 0.0 2.7 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal Sen15 PF09631.5 EMD59336.1 - 2.6e-25 88.5 0.0 4.2e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 EMD59338.1 - 1.8e-39 133.3 4.1 3.6e-39 132.3 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Gly-zipper_OmpA PF13436.1 EMD59339.1 - 0.046 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Neur_chan_memb PF02932.11 EMD59339.1 - 0.13 12.1 2.3 0.21 11.4 1.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 EMD59339.1 - 0.66 9.8 5.8 0.86 9.4 4.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rick_17kDa_Anti PF05433.10 EMD59339.1 - 3 7.5 10.3 0.36 10.5 4.2 1.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EMD59339.1 - 6.4 6.5 13.6 0.84 9.3 6.4 1.7 2 0 0 2 2 2 0 Glycine zipper ERG4_ERG24 PF01222.12 EMD59340.1 - 9.2e-163 541.7 6.6 1.1e-162 541.5 4.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EMD59340.1 - 0.00028 20.2 0.2 0.00073 18.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 EMD59341.1 - 4.5e-14 52.1 0.0 6.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EMD59341.1 - 6.4e-06 26.0 0.0 0.004 16.9 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat NrfD_2 PF14589.1 EMD59341.1 - 0.0095 15.6 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 1 Polysulfide reductase ATG27 PF09451.5 EMD59341.1 - 0.13 11.4 8.8 1.7 7.8 6.2 2.4 1 1 1 2 2 2 0 Autophagy-related protein 27 Dynamin_N PF00350.18 EMD59342.1 - 2.3e-16 60.0 4.4 3e-16 59.6 0.0 3.2 2 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMD59342.1 - 6.8e-06 26.0 0.4 0.00012 22.0 0.3 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EMD59342.1 - 0.00027 21.2 0.0 0.00027 21.2 0.0 2.8 3 1 0 3 3 3 1 ABC transporter DUF4201 PF13870.1 EMD59342.1 - 0.00027 20.4 2.2 0.00027 20.4 1.6 3.2 4 0 0 4 4 3 1 Domain of unknown function (DUF4201) DUF258 PF03193.11 EMD59342.1 - 0.00063 18.9 0.0 0.0062 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMD59342.1 - 0.001 18.2 0.2 0.0075 15.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin IIGP PF05049.8 EMD59342.1 - 0.002 17.0 0.3 0.0092 14.8 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EMD59342.1 - 0.0083 16.6 0.0 0.03 14.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein PRK PF00485.13 EMD59342.1 - 0.011 15.3 0.1 0.089 12.3 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 EMD59342.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PEP-utilisers_N PF05524.8 EMD59342.1 - 0.052 13.3 10.9 0.29 10.9 0.0 3.6 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF904 PF06005.7 EMD59342.1 - 1 9.7 12.0 1.4 9.2 1.2 3.7 3 0 0 3 3 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EMD59342.1 - 1.3 9.3 20.0 0.22 11.8 1.5 4.4 5 0 0 5 5 4 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 EMD59342.1 - 4.3 6.6 12.1 3.3 7.0 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Peptidase_M66 PF10462.4 EMD59343.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 zf-RING_UBOX PF13445.1 EMD59344.1 - 2.8e-09 36.5 2.0 5e-09 35.7 1.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMD59344.1 - 3.2e-09 36.4 2.1 6.1e-09 35.5 1.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD59344.1 - 3.4e-07 30.1 3.1 6.6e-07 29.2 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD59344.1 - 1e-05 25.5 2.2 1.8e-05 24.7 1.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD59344.1 - 1.1e-05 24.9 2.9 2e-05 24.1 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD59344.1 - 0.00019 21.0 2.5 0.00035 20.2 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD59344.1 - 0.0014 18.2 1.1 0.0031 17.1 0.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD59344.1 - 0.0014 18.4 1.7 0.0021 17.8 1.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMD59344.1 - 0.028 14.3 3.2 0.062 13.1 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 EMD59344.1 - 0.071 12.3 0.2 0.098 11.8 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 EMD59344.1 - 0.1 12.1 0.6 0.16 11.4 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EMD59344.1 - 0.11 12.5 1.4 0.27 11.2 1.0 1.7 1 1 0 1 1 1 0 RING-variant domain TLV_coat PF00429.14 EMD59346.1 - 0.12 10.8 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Pkinase PF00069.20 EMD59349.1 - 0.026 13.6 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Peptidase_U40 PF10464.4 EMD59349.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase U40 Fungal_trans_2 PF11951.3 EMD59350.1 - 9.4e-11 40.9 1.2 4.2e-10 38.7 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Auts2 PF15336.1 EMD59350.1 - 0.3 11.1 4.0 0.81 9.6 1.2 2.1 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein PhyH PF05721.8 EMD59351.1 - 6.1e-11 42.7 0.0 1.2e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) WD40 PF00400.27 EMD59352.1 - 9.4e-18 63.3 15.8 0.00022 20.9 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat TF_Zn_Ribbon PF08271.7 EMD59352.1 - 0.0095 15.2 0.4 0.0095 15.2 0.3 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding eIF2A PF08662.6 EMD59352.1 - 0.089 12.4 0.1 3.2 7.4 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A zf-RING_3 PF14369.1 EMD59352.1 - 3.5 7.6 8.2 9 6.3 0.2 2.7 1 1 1 2 2 2 0 zinc-finger AA_permease_2 PF13520.1 EMD59353.1 - 2.6e-62 210.7 50.3 3.1e-62 210.5 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD59353.1 - 3.3e-34 118.0 45.3 4.3e-34 117.6 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sec16_C PF12931.2 EMD59354.1 - 3.1e-101 338.8 0.0 4.1e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EMD59354.1 - 4.6e-32 110.4 0.0 1.4e-31 108.8 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EMD59355.1 - 8.9e-20 70.7 0.0 4e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD59355.1 - 3.9e-15 56.8 0.0 2.6e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD59355.1 - 1.8e-09 38.0 0.2 5.3e-09 36.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD59355.1 - 8.8e-06 25.5 0.0 2.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMD59355.1 - 0.0023 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3431 PF11913.3 EMD59357.1 - 9.4e-19 67.7 0.1 1.5e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Gly-zipper_OmpA PF13436.1 EMD59357.1 - 0.0044 16.6 1.7 0.009 15.6 1.2 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Methyltransf_11 PF08241.7 EMD59358.1 - 6.8e-11 42.5 0.3 1.3e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD59358.1 - 8.2e-06 26.2 0.3 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD59358.1 - 5.2e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD59358.1 - 5.7e-05 22.8 0.0 8.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD59358.1 - 0.00026 20.6 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD59358.1 - 0.032 14.8 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Abi PF02517.11 EMD59359.1 - 7.8e-13 48.3 13.8 7.8e-13 48.3 9.5 2.6 2 1 1 3 3 3 1 CAAX protease self-immunity eIF-6 PF01912.13 EMD59361.1 - 1.3e-82 275.6 1.9 1.8e-82 275.2 1.4 1.2 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EMD59361.1 - 0.11 12.2 0.6 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Phage holin family 6 Es2 PF09751.4 EMD59362.1 - 4.1e-91 306.4 2.4 5.2e-91 306.1 1.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Sds3 PF08598.6 EMD59363.1 - 0.00039 20.0 11.5 0.00039 20.0 8.0 3.9 2 2 1 3 3 3 1 Sds3-like XPC-binding PF09280.6 EMD59365.1 - 5.3e-24 83.4 13.7 9.9e-24 82.5 9.5 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EMD59365.1 - 8e-20 70.0 0.1 1.2e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMD59365.1 - 4.7e-15 54.9 4.2 1.1e-08 34.6 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EMD59365.1 - 5.4e-08 32.4 0.1 9e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EMD59365.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EMD59365.1 - 0.012 15.1 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EMD59365.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD59365.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EMD59365.1 - 0.12 12.2 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubiquitin_2 PF14560.1 EMD59365.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Kri1_C PF12936.2 EMD59366.1 - 2.8e-27 94.4 1.1 2.8e-27 94.4 0.8 4.6 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EMD59366.1 - 7.9e-27 93.4 18.3 7.9e-27 93.4 12.7 6.0 5 2 2 7 7 7 1 KRI1-like family PH PF00169.24 EMD59367.1 - 1.1e-09 38.3 0.1 9.1e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EMD59367.1 - 4.9e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EMD59367.1 - 2.1 8.6 4.4 3.3 8.0 0.9 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain ubiquitin PF00240.18 EMD59368.1 - 4.1e-12 45.3 0.0 8.5e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMD59368.1 - 6.4e-05 22.5 0.0 0.00015 21.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMD59368.1 - 0.022 15.0 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S14 PF00253.16 EMD59369.1 - 5.4e-16 57.7 0.6 6e-16 57.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e CAP PF00188.21 EMD59371.1 - 3.2e-05 24.3 0.0 4.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1214 PF06742.6 EMD59372.1 - 0.1 13.0 0.1 0.18 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1214) Bys1 PF04681.7 EMD59373.1 - 0.044 13.4 1.1 0.046 13.4 0.2 1.4 2 0 0 2 2 2 0 Blastomyces yeast-phase-specific protein DUF336 PF03928.9 EMD59374.1 - 6.5e-30 103.6 1.9 9.2e-30 103.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Death PF00531.17 EMD59374.1 - 0.025 14.3 0.5 0.044 13.5 0.3 1.3 1 0 0 1 1 1 0 Death domain adh_short PF00106.20 EMD59376.1 - 3.3e-15 56.3 0.1 1.4e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD59376.1 - 4.4e-08 33.1 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD59376.1 - 1.2e-05 25.0 0.1 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EMD59376.1 - 0.0016 18.5 0.3 0.0033 17.5 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMD59376.1 - 0.01 16.2 0.2 0.025 14.9 0.2 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EMD59376.1 - 0.017 14.8 1.5 0.15 11.8 1.3 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Phage_capsid PF05065.8 EMD59376.1 - 0.058 12.5 0.1 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage capsid family 2-Hacid_dh_C PF02826.14 EMD59376.1 - 0.1 11.7 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIR2 PF02146.12 EMD59377.1 - 1.1e-36 126.1 0.0 1.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF983 PF06170.7 EMD59377.1 - 0.21 11.7 0.8 1.8 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF983) MFS_1 PF07690.11 EMD59378.1 - 5.3e-41 140.5 23.2 5.3e-41 140.5 16.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59378.1 - 7.3e-12 44.6 8.2 7.3e-12 44.6 5.7 3.2 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMD59378.1 - 0.00014 20.1 1.3 0.00021 19.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_kinase PF02595.10 EMD59379.1 - 6.6e-54 183.0 1.0 8.1e-54 182.7 0.7 1.0 1 0 0 1 1 1 1 Glycerate kinase family FAD_binding_3 PF01494.14 EMD59380.1 - 3.7e-25 88.7 0.0 3.5e-24 85.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EMD59380.1 - 6.5e-05 21.7 0.2 0.0013 17.4 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EMD59380.1 - 0.00025 20.9 0.3 0.00065 19.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD59380.1 - 0.019 13.8 0.1 0.096 11.5 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD59380.1 - 0.039 12.7 0.6 0.085 11.6 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain zf-CCCH PF00642.19 EMD59381.1 - 6.3e-07 28.9 14.9 0.003 17.1 1.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF349 PF03993.7 EMD59381.1 - 5.6 7.2 7.8 0.4 10.8 0.3 2.7 2 2 1 3 3 3 0 Domain of Unknown Function (DUF349) GST_C_3 PF14497.1 EMD59382.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD59382.1 - 1.8e-06 27.8 0.1 3.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD59382.1 - 8.3e-05 22.4 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD59382.1 - 0.047 13.8 0.0 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribosomal_S7e PF01251.13 EMD59383.1 - 1.6e-79 265.8 0.2 1.8e-79 265.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e MARVEL PF01284.18 EMD59384.1 - 1.2e-18 67.2 0.2 1.6e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Amastin PF07344.6 EMD59384.1 - 0.00072 19.1 0.2 0.012 15.2 0.2 2.3 2 1 0 2 2 2 1 Amastin surface glycoprotein Mit_proteolip PF08039.6 EMD59384.1 - 0.14 12.1 0.2 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial proteolipid DUF2069 PF09842.4 EMD59384.1 - 0.37 10.7 3.3 0.3 11.0 0.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2069) SNARE PF05739.14 EMD59385.1 - 2.5e-07 30.3 0.9 3.4e-07 29.8 0.6 1.2 1 0 0 1 1 1 1 SNARE domain ADK PF00406.17 EMD59386.1 - 1.9e-58 196.6 0.0 2.6e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMD59386.1 - 5e-14 51.6 0.0 1.4e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EMD59386.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD59386.1 - 0.0017 19.1 0.0 0.0034 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD59386.1 - 0.0034 16.5 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EMD59386.1 - 0.064 13.5 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EMD59386.1 - 0.12 12.5 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNA12 PF10443.4 EMD59387.1 - 6.8e-168 558.6 0.1 1.5e-167 557.4 0.0 1.6 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 EMD59387.1 - 0.0001 21.8 0.0 0.00051 19.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EMD59387.1 - 0.00024 20.8 0.1 0.0016 18.1 0.0 2.3 3 0 0 3 3 3 1 Archaeal ATPase RRM_6 PF14259.1 EMD59387.1 - 0.0029 17.5 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EMD59387.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_16 PF13191.1 EMD59387.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NUDIX PF00293.23 EMD59388.1 - 2.1e-15 56.5 0.0 3.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AICARFT_IMPCHas PF01808.13 EMD59389.1 - 2.3e-111 371.8 0.0 3e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EMD59389.1 - 1.2e-23 82.8 0.0 2.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain CHZ PF09649.5 EMD59390.1 - 2e-15 55.6 1.7 2e-15 55.6 1.1 1.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ Adaptin_binding PF10199.4 EMD59390.1 - 4.9 7.4 13.3 5.3 7.3 9.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Glu_synthase PF01645.12 EMD59391.1 - 1.6e-158 527.4 0.0 7e-158 525.3 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EMD59391.1 - 2.7e-139 463.9 0.0 3.8e-139 463.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EMD59391.1 - 1.2e-119 398.9 0.0 2.1e-119 398.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EMD59391.1 - 6.7e-68 227.6 0.7 1.2e-67 226.8 0.5 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EMD59391.1 - 6.4e-22 77.2 0.1 1.5e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EMD59391.1 - 3.3e-18 66.2 0.0 1e-17 64.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD59391.1 - 4.7e-11 43.1 0.1 7.2e-05 22.9 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD59391.1 - 3.6e-09 36.4 0.0 1.3e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD59391.1 - 1.3e-07 31.9 0.3 0.00013 22.3 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD59391.1 - 1.9e-06 27.2 0.1 3.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EMD59391.1 - 1.3e-05 23.8 0.2 1.3e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EMD59391.1 - 5.8e-05 22.1 1.1 0.00019 20.4 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMD59391.1 - 0.00011 21.2 0.3 0.00011 21.2 0.2 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMD59391.1 - 0.00019 21.6 0.1 1 9.6 0.0 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FMO-like PF00743.14 EMD59391.1 - 0.00063 18.0 0.4 0.31 9.1 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Thi4 PF01946.12 EMD59391.1 - 0.00067 18.8 0.1 0.0021 17.2 0.1 1.8 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EMD59391.1 - 0.0022 17.1 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMD59391.1 - 0.0028 17.2 0.4 0.081 12.4 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EMD59391.1 - 0.0035 16.4 0.2 0.0035 16.4 0.1 1.6 2 0 0 2 2 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD59391.1 - 0.0069 15.3 0.1 0.98 8.2 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EMD59391.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 EMD59391.1 - 0.017 14.9 0.4 1.8 8.4 0.1 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.1 EMD59391.1 - 0.032 14.0 0.1 0.18 11.5 0.0 2.4 3 0 0 3 3 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EMD59391.1 - 0.04 14.0 0.1 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 EMD59391.1 - 0.059 12.8 0.2 0.24 10.8 0.1 2.0 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_binding_10 PF13460.1 EMD59391.1 - 0.064 13.2 0.4 0.82 9.6 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding FMN_dh PF01070.13 EMD59391.1 - 0.12 11.1 0.4 0.48 9.2 0.4 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase MADF_DNA_bdg PF10545.4 EMD59391.1 - 0.14 12.3 1.0 0.33 11.1 0.7 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GIDA PF01134.17 EMD59391.1 - 0.46 9.2 2.6 0.4 9.4 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Ank_4 PF13637.1 EMD59392.1 - 1.1e-25 89.4 4.3 2.2e-10 40.7 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD59392.1 - 1.2e-25 89.6 0.8 2e-15 56.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD59392.1 - 2.2e-24 83.9 4.3 3.6e-07 29.6 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EMD59392.1 - 1.1e-12 46.9 1.0 0.0022 18.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMD59392.1 - 1e-09 38.2 2.1 6.1e-05 23.1 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Toxin_56 PF15534.1 EMD59392.1 - 0.044 14.2 0.0 9.6 6.7 0.0 2.8 1 1 2 3 3 3 0 Putative toxin 56 DUF3521 PF12035.3 EMD59392.1 - 0.37 10.6 1.8 19 5.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3521) DUF1311 PF07007.7 EMD59393.1 - 0.049 13.7 0.1 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) DUF2274 PF10038.4 EMD59393.1 - 0.14 12.2 0.6 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) AAA_22 PF13401.1 EMD59394.1 - 1.5e-05 25.1 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD59394.1 - 2.2e-05 24.1 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MutS_III PF05192.13 EMD59394.1 - 0.054 13.2 3.1 3.6 7.3 0.3 2.5 2 0 0 2 2 2 0 MutS domain III AAA PF00004.24 EMD59394.1 - 0.096 12.8 0.1 0.94 9.6 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1664 PF07889.7 EMD59394.1 - 0.65 9.8 6.7 4.2 7.1 0.7 4.0 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) DDE_1 PF03184.14 EMD59396.1 - 5.9e-10 38.6 0.0 6.8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldedh PF00171.17 EMD59397.1 - 1.2e-155 518.4 0.5 1.4e-155 518.1 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 EMD59397.1 - 3e-17 62.3 0.2 1.7e-16 59.9 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain LuxC PF05893.9 EMD59397.1 - 1.3e-05 24.0 0.0 3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMD59397.1 - 0.0063 15.7 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) SnoaL_4 PF13577.1 EMD59398.1 - 1.9e-23 82.7 0.1 2.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain PAH PF02671.16 EMD59398.1 - 0.047 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF4200 PF13863.1 EMD59398.1 - 0.1 12.5 0.5 0.14 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RPE65 PF03055.10 EMD59399.1 - 3.7e-126 421.5 0.0 4.3e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NmrA PF05368.8 EMD59400.1 - 1.8e-25 89.5 0.0 3.8e-25 88.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD59400.1 - 3e-07 30.6 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD59400.1 - 0.0025 16.5 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD59400.1 - 0.0047 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMD59400.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HEAT PF02985.17 EMD59401.1 - 1.5e-11 43.3 5.6 2.4 8.4 0.0 10.2 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EMD59401.1 - 0.95 10.0 20.9 26 5.4 0.1 10.2 12 0 0 12 12 12 0 HEAT-like repeat Transcrip_reg PF01709.15 EMD59402.1 - 5.8e-67 225.2 0.5 6.8e-67 225.0 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator ECH PF00378.15 EMD59404.1 - 1.3e-23 83.4 0.0 1.5e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1640 PF07798.6 EMD59405.1 - 6.7e-13 49.0 1.3 9.3e-13 48.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) IncA PF04156.9 EMD59405.1 - 0.00089 18.9 2.6 0.0015 18.1 1.6 1.5 1 1 0 1 1 1 1 IncA protein DUF2353 PF09789.4 EMD59405.1 - 0.0052 16.0 1.5 0.008 15.4 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TFX_C PF14601.1 EMD59407.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term DUF3384 PF11864.3 EMD59408.1 - 2.1e-73 247.4 0.0 3.5e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EMD59408.1 - 6e-54 182.2 0.0 9.8e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EMD59408.1 - 3.9e-33 115.0 1.6 5.5e-29 101.3 0.6 3.2 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.10 EMD59409.1 - 3.4e-177 589.1 1.4 5.3e-177 588.4 0.2 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EMD59409.1 - 7.7e-152 505.1 0.4 1.6e-151 504.1 0.2 1.6 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EMD59409.1 - 1.5e-15 56.8 0.0 8.8e-15 54.3 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMD59409.1 - 0.024 14.5 0.1 0.26 11.1 0.0 2.9 2 0 0 2 2 2 0 Exportin 1-like protein Mannitol_dh_C PF08125.8 EMD59410.1 - 2e-76 256.4 0.0 2.9e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EMD59410.1 - 3.6e-45 153.6 0.0 6.2e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Ras PF00071.17 EMD59411.1 - 7.1e-48 162.0 0.0 4.7e-46 156.1 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMD59411.1 - 2e-15 57.3 0.0 5e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD59411.1 - 2.8e-11 42.9 0.0 2.6e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD59411.1 - 5.5e-08 32.4 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD59411.1 - 9.4e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD59411.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMD59411.1 - 0.0036 16.8 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Choline_transpo PF04515.7 EMD59412.1 - 2e-14 53.0 13.0 2e-14 53.0 9.0 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter Spc97_Spc98 PF04130.8 EMD59413.1 - 1.1e-130 436.5 1.4 1.4e-130 436.2 1.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family adh_short PF00106.20 EMD59414.1 - 6e-15 55.5 0.7 9.8e-15 54.8 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD59414.1 - 1.2e-07 31.5 0.2 9.3e-07 28.6 0.0 2.2 2 1 1 3 3 3 1 KR domain Epimerase PF01370.16 EMD59414.1 - 0.00021 20.8 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1843 PF08898.5 EMD59416.1 - 0.041 13.9 0.3 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF3567 PF12091.3 EMD59416.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Metallophos PF00149.23 EMD59417.1 - 3e-39 134.4 0.0 4.3e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EMD59417.1 - 5.1e-30 103.3 0.9 1.4e-29 101.9 0.7 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EMD59417.1 - 1.9e-08 33.7 0.5 4.2e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EMD59417.1 - 2.4e-07 30.0 1.5 0.00032 20.1 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD59417.1 - 4e-05 23.2 1.3 0.019 14.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD59417.1 - 0.0018 18.2 0.1 0.0018 18.2 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD59417.1 - 0.033 14.8 0.7 8 7.2 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMD59417.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMD59417.1 - 0.1 12.6 0.3 0.25 11.5 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-TFIIB PF13453.1 EMD59417.1 - 0.17 11.1 0.0 0.44 9.7 0.0 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Spt4 PF06093.8 EMD59418.1 - 1.1e-31 108.5 0.3 1.3e-31 108.2 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EMD59418.1 - 0.074 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein Mito_carr PF00153.22 EMD59419.1 - 8.5e-44 147.2 9.7 1.1e-18 66.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.1 EMD59420.1 - 2e-16 60.6 0.1 2.9e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD59420.1 - 1.9e-13 50.7 0.1 2.7e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4094 PF13334.1 EMD59421.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) AMP-binding PF00501.23 EMD59422.1 - 1.1e-82 277.6 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.15 EMD59423.1 - 1e-150 501.3 0.0 1.2e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMD59423.1 - 1.2e-11 44.2 0.2 1.9e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMD59423.1 - 2e-09 36.9 0.0 3.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMD59423.1 - 4.3e-09 35.7 0.0 7.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMD59423.1 - 4e-08 32.4 0.3 8.4e-08 31.3 0.2 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EMD59423.1 - 0.00027 19.3 0.1 0.00035 18.9 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EMD59423.1 - 0.0082 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SelA PF03841.8 EMD59423.1 - 0.064 11.9 0.1 0.24 10.1 0.1 1.9 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase CPSase_L_D2 PF02786.12 EMD59423.1 - 0.096 11.9 0.6 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Velvet PF11754.3 EMD59425.1 - 3.5e-63 212.8 0.0 7.3e-63 211.8 0.0 1.5 1 0 0 1 1 1 1 Velvet factor RTA1 PF04479.8 EMD59426.1 - 1.5e-21 76.9 0.7 2.3e-21 76.3 0.5 1.2 1 0 0 1 1 1 1 RTA1 like protein TRAPPC10 PF12584.3 EMD59427.1 - 1.5e-27 95.9 0.0 2.9e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EMD59427.1 - 0.00069 19.1 0.4 0.0013 18.2 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Peptidase_S10 PF00450.17 EMD59428.1 - 8.9e-97 324.8 1.9 1.1e-96 324.5 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Rep_fac_C PF08542.6 EMD59429.1 - 1.4e-19 69.8 0.1 3.4e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMD59429.1 - 7e-12 45.2 0.0 6.8e-10 38.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EMD59429.1 - 1.5e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMD59429.1 - 6e-07 29.4 0.0 1.7e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD59429.1 - 1.1e-05 25.5 0.0 0.00026 21.0 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMD59429.1 - 1.9e-05 24.8 0.1 0.02 15.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMD59429.1 - 2.5e-05 23.9 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 EMD59429.1 - 3.4e-05 23.0 0.1 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EMD59429.1 - 4.7e-05 22.2 0.0 0.013 14.2 0.0 2.4 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EMD59429.1 - 0.00025 20.6 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMD59429.1 - 0.00029 20.3 0.0 0.032 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EMD59429.1 - 0.00082 18.9 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EMD59429.1 - 0.001 18.5 0.0 0.066 12.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD59429.1 - 0.0018 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EMD59429.1 - 0.002 17.3 0.0 0.013 14.6 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EMD59429.1 - 0.0056 16.2 0.0 0.0085 15.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EMD59429.1 - 0.0082 15.6 0.1 0.23 10.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EMD59429.1 - 0.013 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EMD59429.1 - 0.017 15.0 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMD59429.1 - 0.018 14.7 0.4 0.074 12.7 0.0 2.2 2 1 0 3 3 3 0 NTPase ArgK PF03308.11 EMD59429.1 - 0.019 13.7 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 EMD59429.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMD59429.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Asp PF00026.18 EMD59430.1 - 3.2e-75 253.3 0.3 3.8e-75 253.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMD59430.1 - 1e-10 41.8 0.0 1.9e-09 37.7 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMD59430.1 - 6.2e-07 29.8 0.7 0.088 13.3 0.1 3.7 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EMD59430.1 - 9.6e-05 21.9 0.0 0.0014 18.1 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMD59430.1 - 0.049 13.4 0.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2284 PF10050.4 EMD59431.1 - 0.14 11.7 1.3 3.9 7.0 0.0 2.1 1 1 1 2 2 2 0 Predicted metal-binding protein (DUF2284) CDK2AP PF09806.4 EMD59431.1 - 4.7 7.3 9.3 12 6.1 6.4 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein FA_desaturase PF00487.19 EMD59432.1 - 2e-37 129.0 24.2 2e-37 129.0 16.7 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMD59432.1 - 5.6e-13 48.5 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4337 PF14235.1 EMD59432.1 - 0.18 11.6 0.4 0.29 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cupin_1 PF00190.17 EMD59433.1 - 3e-31 107.7 0.0 5.3e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EMD59433.1 - 1.7e-25 88.3 0.9 6e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMD59433.1 - 3.1e-11 42.4 0.0 6.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMD59433.1 - 2.3e-06 27.3 0.2 0.00077 19.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EMD59433.1 - 5.4e-05 22.8 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 Cupin FdtA PF05523.6 EMD59433.1 - 0.001 18.5 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 WxcM-like, C-terminal ARD PF03079.9 EMD59433.1 - 0.065 13.1 3.2 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 ARD/ARD' family DUF1275 PF06912.6 EMD59434.1 - 1.3e-35 122.4 14.6 1.8e-35 122.0 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Mito_carr PF00153.22 EMD59435.1 - 2.3e-29 100.9 4.2 3.5e-12 45.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CRT10 PF08728.5 EMD59435.1 - 6.8e-13 47.5 0.0 9.3e-09 33.8 0.0 2.1 2 0 0 2 2 2 2 CRT10 Citrate_synt PF00285.16 EMD59436.1 - 3.7e-102 341.7 0.0 4.3e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EMD59436.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone RRM_1 PF00076.17 EMD59437.1 - 1.9e-06 27.4 0.0 4.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD59437.1 - 9.8e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD59437.1 - 2.7e-05 24.0 0.0 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EMD59437.1 - 0.00045 20.4 0.0 0.0021 18.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase II-binding domain. CLPTM1 PF05602.7 EMD59438.1 - 2.6e-163 543.7 0.4 3.3e-163 543.4 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Tachylectin PF14517.1 EMD59438.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Tachylectin DUF788 PF05620.6 EMD59438.1 - 0.48 10.2 4.7 0.66 9.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Lysine_decarbox PF03641.9 EMD59439.1 - 4.4e-30 104.2 0.0 6.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase MAPEG PF01124.13 EMD59440.1 - 3.6e-10 39.5 5.2 6.1e-10 38.7 3.6 1.3 1 0 0 1 1 1 1 MAPEG family Aminotran_3 PF00202.16 EMD59441.1 - 4.6e-98 328.2 0.0 5.8e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SET PF00856.23 EMD59442.1 - 2.1e-22 80.1 1.8 7.2e-22 78.4 0.1 2.8 2 1 0 2 2 2 1 SET domain SRI PF08236.6 EMD59442.1 - 2.7e-21 75.2 9.3 6.4e-21 74.1 6.5 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EMD59442.1 - 3.3e-06 26.4 1.0 3.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.21 EMD59442.1 - 5.7e-06 26.0 0.7 1.2e-05 25.0 0.5 1.6 1 0 0 1 1 1 1 WW domain DUF2956 PF11169.3 EMD59442.1 - 2.3 8.2 7.6 2.2 8.2 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) VEFS-Box PF09733.4 EMD59444.1 - 6.3e-05 22.6 0.2 0.00011 21.9 0.2 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Tox-SHH PF15652.1 EMD59444.1 - 0.035 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature F-box-like PF12937.2 EMD59445.1 - 0.0027 17.3 3.0 0.0058 16.3 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EMD59445.1 - 0.3 10.7 6.4 1.6 8.4 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) RNase_P_Rpp14 PF01900.14 EMD59447.1 - 0.037 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF3209 PF11483.3 EMD59448.1 - 0.001 19.3 1.3 0.001 19.3 0.9 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF3209) FlaC_arch PF05377.6 EMD59448.1 - 0.5 10.2 20.1 17 5.3 0.0 8.3 7 2 1 8 8 8 0 Flagella accessory protein C (FlaC) Toxin_52 PF15605.1 EMD59448.1 - 4.8 7.1 8.5 9.9 6.1 0.1 4.9 4 0 0 4 4 4 0 Putative toxin 52 TIP49 PF06068.8 EMD59449.1 - 7.3e-173 574.8 3.9 8.6e-173 574.6 2.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EMD59449.1 - 3.1e-09 36.2 1.9 2.4e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EMD59449.1 - 3.4e-08 33.7 0.5 4.6e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EMD59449.1 - 2.6e-06 26.4 0.3 4.2e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EMD59449.1 - 9.8e-05 22.4 0.0 0.0015 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EMD59449.1 - 0.00042 19.5 0.8 0.0085 15.2 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMD59449.1 - 0.00046 20.0 0.0 0.96 9.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD59449.1 - 0.0006 19.9 0.0 0.35 11.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 EMD59449.1 - 0.00062 19.5 1.0 0.46 10.2 0.0 3.5 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD59449.1 - 0.022 14.1 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD59449.1 - 0.027 14.2 0.0 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EMD59449.1 - 0.05 12.4 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Tox-REase-2 PF15646.1 EMD59449.1 - 0.07 13.0 0.2 5.1 6.9 0.1 2.5 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 AAA_11 PF13086.1 EMD59449.1 - 0.072 12.6 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain LicD PF04991.8 EMD59450.1 - 7.1e-34 117.7 9.0 8.3e-33 114.2 6.2 2.2 1 1 0 1 1 1 1 LicD family DDE_1 PF03184.14 EMD59451.1 - 8.3e-31 106.8 0.0 1.1e-16 60.6 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Y1_Tnp PF01797.11 EMD59451.1 - 0.0071 16.1 0.8 0.015 15.1 0.5 1.5 1 0 0 1 1 1 1 Transposase IS200 like HTH_Tnp_Tc5 PF03221.11 EMD59451.1 - 0.13 12.0 2.3 13 5.7 0.2 2.5 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain NACHT PF05729.7 EMD59452.1 - 2.1e-26 92.5 0.1 3.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD59452.1 - 4.2e-25 88.5 0.8 1.1e-24 87.1 0.5 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 EMD59452.1 - 0.0092 15.9 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD59452.1 - 0.0094 16.0 0.0 0.025 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD59452.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain WLM PF08325.5 EMD59453.1 - 4.1e-46 157.1 0.0 6.5e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.4 EMD59453.1 - 4.5e-05 23.1 0.1 6.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 EMD59453.1 - 0.0024 17.7 0.1 0.0047 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 ubiquitin PF00240.18 EMD59453.1 - 0.004 16.5 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_MA_2 PF13485.1 EMD59453.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily Oxidored_FMN PF00724.15 EMD59455.1 - 2.4e-50 171.4 0.0 3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pericardin_rpt PF07054.6 EMD59456.1 - 1.8 8.5 4.6 0.68 9.8 1.4 1.7 2 0 0 2 2 2 0 Pericardin like repeat Sugar_tr PF00083.19 EMD59457.1 - 1.8e-107 359.7 25.8 2.2e-107 359.4 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59457.1 - 3.3e-14 52.3 46.4 6.5e-11 41.5 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Coagulin PF02035.10 EMD59457.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Coagulin Ribosomal_L28e PF01778.12 EMD59458.1 - 1.9e-27 96.0 0.1 3.4e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EMD59458.1 - 8.3e-19 67.5 20.1 8.3e-19 67.5 13.9 3.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EMD59458.1 - 0.00044 19.4 8.1 0.00055 19.1 5.6 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EMD59458.1 - 0.041 11.8 17.3 0.066 11.1 12.0 1.3 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 EMD59458.1 - 0.17 10.2 7.1 0.2 9.9 4.9 1.1 1 0 0 1 1 1 0 SGT1 protein Cwf_Cwc_15 PF04889.7 EMD59458.1 - 7.3 6.2 21.9 24 4.5 15.2 1.9 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TrmE_N PF10396.4 EMD59459.1 - 1.2e-34 118.7 0.0 3.2e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EMD59459.1 - 9.8e-21 73.9 0.1 2.8e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EMD59459.1 - 7.2e-17 61.4 0.1 1.4e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD59459.1 - 6.8e-09 35.1 0.1 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMD59459.1 - 7.9e-07 28.6 0.2 0.00022 20.7 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMD59459.1 - 1.1e-06 28.5 0.4 4e-05 23.4 0.0 2.3 1 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EMD59459.1 - 0.003 18.0 0.1 0.01 16.2 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EMD59459.1 - 0.027 13.6 0.0 0.094 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMD59459.1 - 0.037 14.3 0.3 0.11 12.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter CDC37_C PF08564.5 EMD59459.1 - 0.13 12.1 0.4 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain Hus1 PF04005.7 EMD59461.1 - 3e-99 331.6 0.0 3.4e-99 331.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Peptidase_A4 PF01828.12 EMD59462.1 - 8.6e-24 83.7 2.3 1e-23 83.5 1.6 1.0 1 0 0 1 1 1 1 Peptidase A4 family Lipocalin_6 PF13944.1 EMD59462.1 - 0.0032 17.5 0.5 0.0089 16.1 0.1 1.9 2 0 0 2 2 2 1 Lipocalin-like domain DUF3491 PF11996.3 EMD59462.1 - 0.083 10.3 0.4 0.3 8.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3491) DUF824 PF05688.6 EMD59462.1 - 0.13 11.9 0.5 0.27 10.8 0.4 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF1996 PF09362.5 EMD59463.1 - 1.3e-89 299.9 1.6 1.6e-89 299.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_HII PF01351.13 EMD59466.1 - 3.2e-46 157.4 0.0 1.1e-45 155.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease HII adh_short PF00106.20 EMD59467.1 - 4.2e-32 111.3 0.2 4.2e-32 111.3 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD59467.1 - 2.3e-13 50.2 0.2 5.3e-13 49.0 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD59467.1 - 2.5e-09 37.2 0.1 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMD59467.1 - 5.2e-06 26.5 0.0 1.1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD59467.1 - 8.6e-05 21.3 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD59467.1 - 0.0066 15.9 0.0 0.0097 15.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD59467.1 - 0.013 14.6 0.3 0.023 13.8 0.2 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) eIF-6 PF01912.13 EMD59467.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 eIF-6 family PUF PF00806.14 EMD59469.1 - 1.8e-63 206.6 13.4 5.9e-09 34.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Inhibitor_I9 PF05922.11 EMD59470.1 - 0.00011 22.6 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M28 PF04389.12 EMD59473.1 - 3.1e-28 98.7 0.2 1.3e-27 96.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD59473.1 - 0.0009 18.7 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Carn_acyltransf PF00755.15 EMD59474.1 - 4.9e-165 549.9 0.0 1.1e-150 502.5 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase RecA PF00154.16 EMD59475.1 - 0.037 13.0 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PMT PF02366.13 EMD59476.1 - 1.9e-84 282.8 15.5 1.9e-84 282.8 10.8 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMD59476.1 - 5.7e-39 133.6 0.9 7.8e-39 133.1 0.6 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 EMD59477.1 - 2.1e-103 346.3 16.9 2.5e-103 346.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59477.1 - 2.7e-30 105.2 49.5 4.2e-28 98.0 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD59477.1 - 0.0027 17.4 0.5 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family Tmemb_18A PF09771.4 EMD59477.1 - 1.2 9.0 3.0 11 6.0 0.1 3.0 2 1 1 3 3 3 0 Transmembrane protein 188 Chs3p PF12271.3 EMD59478.1 - 6.2e-97 324.1 7.2 7.3e-97 323.8 5.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit YajC PF02699.10 EMD59478.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit Cytochrom_B_C PF00032.12 EMD59478.1 - 4.6 7.5 11.2 0.92 9.7 0.2 2.9 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD MerC PF03203.9 EMD59478.1 - 7.9 6.8 16.3 0.94 9.8 0.7 3.7 2 2 2 4 4 4 0 MerC mercury resistance protein DUF973 PF06157.6 EMD59478.1 - 8.8 5.2 17.1 4.3 6.2 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF973) Ssl1 PF04056.9 EMD59479.1 - 7.3e-63 211.6 0.1 1e-60 204.6 0.0 2.1 1 1 1 2 2 2 2 Ssl1-like C1_4 PF07975.7 EMD59479.1 - 3.6e-14 52.4 11.2 3.6e-14 52.4 7.7 3.6 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EMD59479.1 - 4e-11 43.3 0.0 5.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMD59479.1 - 0.00029 20.6 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EMD59479.1 - 0.28 10.4 4.5 0.73 9.0 3.1 1.7 1 0 0 1 1 1 0 Transcription factor Tfb4 zf-HIT PF04438.11 EMD59479.1 - 5.7 6.6 27.5 0.029 14.0 3.3 3.9 5 0 0 5 5 5 0 HIT zinc finger FAA_hydrolase PF01557.13 EMD59480.1 - 4.2e-61 206.1 0.0 5.3e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 EMD59480.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) HLH PF00010.21 EMD59483.1 - 7.3e-13 48.0 0.4 1.4e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EMD59483.1 - 0.027 13.9 0.1 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein F-112 PF09645.5 EMD59483.1 - 6.4 6.7 8.4 0.87 9.4 2.2 2.2 2 1 0 2 2 2 0 F-112 protein DUF3402 PF11882.3 EMD59484.1 - 4.8e-152 506.7 0.0 6.2e-152 506.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EMD59484.1 - 3.9e-87 291.8 0.0 6.1e-87 291.1 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein FMN_dh PF01070.13 EMD59485.1 - 5e-107 357.8 0.0 6e-107 357.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMD59485.1 - 2.4e-21 75.3 0.0 5.1e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMD59485.1 - 8e-07 28.2 0.1 1.3e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMD59485.1 - 4e-06 25.9 1.1 0.0011 17.9 0.2 2.5 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMD59485.1 - 0.016 14.3 0.1 0.036 13.2 0.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 EMD59485.1 - 0.024 13.8 0.0 0.078 12.2 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein ATP11 PF06644.6 EMD59485.1 - 0.036 13.5 2.8 0.061 12.8 0.0 2.4 3 0 0 3 3 3 0 ATP11 protein DUF3043 PF11241.3 EMD59486.1 - 0.031 13.8 6.0 0.093 12.3 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Dishevelled PF02377.10 EMD59486.1 - 0.12 12.6 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Dishevelled specific domain CopD PF05425.8 EMD59486.1 - 0.19 11.9 1.5 0.18 12.0 0.3 1.7 2 1 0 2 2 2 0 Copper resistance protein D TMEM171 PF15471.1 EMD59486.1 - 1.5 7.5 7.3 0.44 9.2 1.5 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 DUF4519 PF15012.1 EMD59486.1 - 1.7 8.5 6.7 3.7 7.5 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4400 PF14348.1 EMD59486.1 - 2.2 7.6 5.8 0.72 9.1 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Glyco_hydro_43 PF04616.9 EMD59488.1 - 3e-68 229.9 1.1 3.9e-68 229.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1996 PF09362.5 EMD59489.1 - 1.8e-84 283.0 0.8 2.3e-84 282.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.11 EMD59490.1 - 9.7e-35 119.9 21.0 9.7e-35 119.9 14.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59490.1 - 3.5e-10 39.0 5.1 3.5e-10 39.0 3.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter adh_short PF00106.20 EMD59491.1 - 1.3e-27 96.7 0.4 1.8e-27 96.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD59491.1 - 2.1e-17 63.6 0.1 3e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD59491.1 - 1.9e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMD59491.1 - 3.8e-06 26.6 1.6 2.1e-05 24.2 1.1 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD59491.1 - 0.001 18.7 1.4 0.005 16.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMD59491.1 - 0.0047 16.9 0.0 0.0075 16.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding LysM PF01476.15 EMD59493.1 - 0.00053 19.8 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain OMPdecase PF00215.19 EMD59494.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Alpha_L_fucos PF01120.12 EMD59495.1 - 5.6e-85 285.2 3.0 7.5e-85 284.8 2.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase PAN_4 PF14295.1 EMD59497.1 - 7.8e-14 51.1 16.1 1.2e-08 34.5 0.4 3.2 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.6 EMD59497.1 - 2.8e-05 23.8 6.5 0.0087 15.8 0.3 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.7 EMD59497.1 - 0.00031 20.3 5.0 0.16 11.6 0.3 2.9 2 0 0 2 2 2 2 PAN-like domain CVNH PF08881.5 EMD59498.1 - 6.7e-08 32.6 1.1 1e-06 28.9 0.7 2.0 1 1 0 1 1 1 1 CVNH domain HIPIP PF01355.12 EMD59498.1 - 0.0047 17.0 0.6 0.0087 16.1 0.4 1.4 1 0 0 1 1 1 1 High potential iron-sulfur protein 7kD_coat PF02495.12 EMD59498.1 - 0.031 13.7 0.2 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 7kD viral coat protein SNF2_N PF00176.18 EMD59499.1 - 5.4e-70 235.5 0.1 8.7e-70 234.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD59499.1 - 7.1e-15 54.6 0.0 2.2e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EMD59499.1 - 2.3e-06 27.3 3.8 8.6e-06 25.4 2.6 2.0 1 0 0 1 1 1 1 HSA DEAD PF00270.24 EMD59499.1 - 3.8e-06 26.4 0.0 8.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EMD59499.1 - 0.0082 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 vMSA PF00695.14 EMD59499.1 - 8.9 5.4 5.1 23 4.0 3.6 1.6 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus NDUF_B8 PF05821.6 EMD59500.1 - 8.4e-05 22.2 0.3 0.00012 21.8 0.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EMD59501.1 - 4.4e-25 88.0 1.7 1e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EMD59501.1 - 2.5e-16 59.2 0.0 6.1e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain HLH PF00010.21 EMD59502.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 EMD59502.1 - 0.074 13.5 0.2 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 NUC194 PF08163.7 EMD59502.1 - 0.15 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 NUC194 domain Methyltransf_16 PF10294.4 EMD59503.1 - 0.15 11.4 0.0 1.8 8.0 0.0 2.2 2 1 0 2 2 2 0 Putative methyltransferase tRNA-synt_2b PF00587.20 EMD59505.1 - 1.4e-46 158.2 0.0 2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD59505.1 - 3.4e-07 30.0 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain ADH_N PF08240.7 EMD59506.1 - 3.1e-26 91.2 0.6 3.1e-26 91.2 0.4 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD59506.1 - 9.8e-16 57.4 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMD59506.1 - 0.052 13.5 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_8 PF08022.7 EMD59507.1 - 8.3e-25 86.6 0.0 1.7e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD59507.1 - 3.5e-22 78.9 0.0 5.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMD59507.1 - 2.9e-17 62.9 11.3 2.9e-17 62.9 7.8 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMD59507.1 - 0.00011 22.3 0.0 0.0003 20.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD59507.1 - 0.1 13.1 0.0 2.8 8.5 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain ADH_N PF08240.7 EMD59509.1 - 5.7e-33 112.9 1.6 7.4e-33 112.5 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD59509.1 - 3.2e-24 84.9 0.3 8.8e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD59509.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 EMD59509.1 - 0.0087 15.6 0.0 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD59509.1 - 0.013 16.0 0.1 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EMD59509.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EMD59509.1 - 0.049 13.4 0.2 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Met_10 PF02475.11 EMD59509.1 - 0.088 12.3 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EMD59509.1 - 0.091 12.1 0.1 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HI0933_like PF03486.9 EMD59509.1 - 0.1 11.0 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein VPS28 PF03997.7 EMD59510.1 - 2.8e-55 186.8 0.2 4.2e-55 186.3 0.2 1.2 1 0 0 1 1 1 1 VPS28 protein Methyltransf_16 PF10294.4 EMD59510.1 - 2.4e-23 82.4 0.0 2.9e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMD59510.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD59510.1 - 0.013 16.0 0.1 0.057 14.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain C-C_Bond_Lyase PF15617.1 EMD59510.1 - 0.062 12.0 0.4 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Noc2 PF03715.8 EMD59511.1 - 5e-126 419.5 0.0 9.1e-126 418.7 0.0 1.4 1 0 0 1 1 1 1 Noc2p family SAD_SRA PF02182.12 EMD59512.1 - 1.1e-25 89.7 0.0 1.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain PAF-AH_p_II PF03403.8 EMD59513.1 - 3.3e-45 153.9 0.0 5.3e-44 150.0 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMD59513.1 - 2.8e-09 36.8 0.0 1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD59513.1 - 4.2e-06 25.8 0.0 1.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMD59513.1 - 0.0003 19.6 0.0 0.00062 18.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EMD59513.1 - 0.00065 19.6 0.0 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD59513.1 - 0.00084 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMD59513.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.15 EMD59513.1 - 0.088 13.0 0.4 4.2 7.5 0.1 2.9 3 1 1 4 4 4 0 Thioesterase domain Ras PF00071.17 EMD59514.1 - 5.1e-42 143.0 0.0 7.1e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD59514.1 - 8.4e-15 55.3 0.0 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD59514.1 - 1.1e-10 41.0 0.0 5e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD59514.1 - 0.00028 20.1 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD59514.1 - 0.00047 19.6 0.0 0.0032 16.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMD59514.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMD59514.1 - 0.00077 18.9 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMD59514.1 - 0.0065 16.6 0.0 0.022 14.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD59514.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMD59514.1 - 0.014 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EMD59514.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD59514.1 - 0.028 14.3 0.1 0.11 12.4 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EMD59514.1 - 0.039 13.4 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 EMD59514.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.5 EMD59514.1 - 0.068 12.3 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit E1-E2_ATPase PF00122.15 EMD59515.1 - 3e-54 183.4 0.7 7.8e-54 182.1 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EMD59515.1 - 7.8e-47 157.2 1.8 6.4e-12 45.4 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EMD59515.1 - 6.2e-41 141.1 2.4 1.4e-40 140.0 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD59515.1 - 3.1e-09 37.2 0.6 1.8e-08 34.7 0.0 2.6 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD59515.1 - 0.0032 17.0 0.2 0.012 15.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 EMD59515.1 - 0.029 13.9 2.7 16 5.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) PCI PF01399.22 EMD59516.1 - 1.6e-08 34.7 0.0 3.3e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 PCI domain Rop-like PF05082.8 EMD59516.1 - 0.052 13.0 1.3 5.9 6.4 0.0 2.4 1 1 1 2 2 2 0 Rop-like Cutinase PF01083.17 EMD59519.1 - 3.1e-46 157.3 3.4 4e-46 157.0 2.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD59519.1 - 8.2e-05 22.1 0.2 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EMD59519.1 - 0.00058 19.4 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) VirJ PF06057.6 EMD59519.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EMD59519.1 - 0.011 15.5 0.3 0.015 15.0 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EMD59519.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EMD59519.1 - 0.015 14.8 0.2 0.043 13.3 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 EMD59519.1 - 0.036 12.7 0.1 0.047 12.3 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Thioesterase PF00975.15 EMD59519.1 - 0.062 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 EMD59519.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_M28 PF04389.12 EMD59520.1 - 6.1e-27 94.5 0.0 1.2e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD59520.1 - 8e-06 25.4 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.16 EMD59520.1 - 1.3e-05 25.2 0.3 4e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_M42 PF05343.9 EMD59520.1 - 0.0027 16.5 0.0 0.0049 15.6 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Tissue_fac PF01108.12 EMD59520.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Tissue factor MFS_1 PF07690.11 EMD59521.1 - 2.1e-13 49.7 41.7 2.1e-13 49.7 28.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD59521.1 - 6.3e-07 29.0 4.8 6.3e-07 29.0 3.3 2.7 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 EVC2_like PF12297.3 EMD59521.1 - 0.21 10.1 0.5 0.31 9.6 0.3 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CN_hydrolase PF00795.17 EMD59522.1 - 1.6e-34 118.8 0.0 2.2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.17 EMD59522.1 - 0.11 12.1 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 PA domain HMG_box PF00505.14 EMD59523.1 - 3.4e-07 30.4 5.8 1.7e-06 28.1 4.0 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD59523.1 - 0.00078 19.7 1.0 0.00078 19.7 0.7 2.2 2 0 0 2 2 2 1 HMG-box domain dsrm PF00035.20 EMD59524.1 - 6.4e-07 29.8 0.0 0.011 16.2 0.0 3.6 3 0 0 3 3 3 2 Double-stranded RNA binding motif PPR_3 PF13812.1 EMD59524.1 - 0.028 14.7 0.2 2.6 8.5 0.1 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain NACHT PF05729.7 EMD59525.1 - 0.00079 19.1 0.4 0.0019 17.8 0.3 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD59525.1 - 0.0015 18.5 0.6 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ssl1 PF04056.9 EMD59525.1 - 0.033 13.8 0.2 0.3 10.6 0.0 2.4 1 1 1 2 2 2 0 Ssl1-like RRM_1 PF00076.17 EMD59526.1 - 5.9e-74 243.6 4.3 2.1e-16 59.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD59526.1 - 5.4e-68 224.9 1.4 9.1e-16 57.5 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD59526.1 - 6.2e-38 128.4 1.0 5.4e-07 29.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD59526.1 - 3.9e-07 29.7 0.4 0.0081 15.8 0.0 4.4 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EMD59526.1 - 3.8e-06 26.5 0.0 0.012 15.3 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Dynein_light PF01221.13 EMD59527.1 - 2.3e-41 139.6 3.1 2.7e-41 139.4 2.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Viral_DNA_bp PF00747.12 EMD59527.1 - 0.066 10.4 0.3 0.07 10.3 0.2 1.0 1 0 0 1 1 1 0 ssDNA binding protein Peptidase_M24 PF00557.19 EMD59527.1 - 0.072 12.6 0.1 0.084 12.4 0.0 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 DUF950 PF06106.6 EMD59527.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Octopine_DH PF02317.12 EMD59527.1 - 0.14 11.8 0.2 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain zinc_ribbon_4 PF13717.1 EMD59528.1 - 0.035 13.7 0.6 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EMD59528.1 - 0.036 13.5 0.6 8.4 5.9 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EMD59528.1 - 0.042 13.4 0.6 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain HET PF06985.6 EMD59529.1 - 1.2e-23 83.8 0.1 4.7e-23 81.8 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Scytalone_dh PF02982.9 EMD59530.1 - 2e-84 280.9 0.9 2.4e-84 280.7 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMD59530.1 - 1.7e-08 34.4 0.6 2.3e-08 33.9 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain RRM_1 PF00076.17 EMD59531.1 - 3.5e-48 161.1 0.0 8e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD59531.1 - 2.1e-27 94.8 0.0 2e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD59531.1 - 1.7e-24 85.4 0.0 2.6e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD59531.1 - 5.8e-07 29.3 0.0 0.0001 22.1 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMD59531.1 - 4.9e-06 26.2 0.1 0.0087 15.8 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Amidohydro_1 PF01979.15 EMD59533.1 - 3e-63 214.5 2.4 6e-63 213.5 1.6 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EMD59533.1 - 1.8e-55 186.2 2.3 3.7e-55 185.2 1.6 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EMD59533.1 - 3e-40 136.0 1.1 4.2e-40 135.6 0.1 1.7 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EMD59533.1 - 6.8e-37 125.4 0.1 1.4e-36 124.4 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EMD59533.1 - 5.9e-07 29.2 5.4 1.9e-06 27.5 3.8 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD59533.1 - 2e-06 27.2 0.2 0.00041 19.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family ADH_zinc_N PF00107.21 EMD59536.1 - 1.4e-19 69.9 0.0 2.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD59536.1 - 3.5e-06 27.9 0.0 5.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Maf PF02545.9 EMD59537.1 - 3.3e-47 160.1 0.0 4.1e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein UAA PF08449.6 EMD59538.1 - 6.5e-11 41.6 20.0 7.9e-11 41.4 13.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMD59538.1 - 1.8e-08 34.1 6.1 1.8e-08 34.1 4.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMD59538.1 - 0.0014 18.6 31.7 0.007 16.3 5.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family Imm27 PF15573.1 EMD59538.1 - 0.048 12.8 0.1 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 27 PPP4R2 PF09184.6 EMD59539.1 - 3.1e-11 43.3 4.1 6.7e-10 38.9 0.0 3.0 2 1 0 2 2 2 1 PPP4R2 RCR PF12273.3 EMD59541.1 - 0.49 10.9 0.0 0.49 10.9 0.0 2.5 2 1 1 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF1129 PF06570.6 EMD59541.1 - 1.1 8.4 14.1 0.024 13.9 3.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Phtf-FEM1B_bdg PF12129.3 EMD59541.1 - 4.7 6.5 8.5 0.26 10.6 1.7 2.0 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Mpv17_PMP22 PF04117.7 EMD59542.1 - 4.7e-24 83.7 1.9 8.4e-24 82.9 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Protocadherin PF08374.6 EMD59544.1 - 2.8 7.5 13.2 0.15 11.6 2.1 2.2 2 0 0 2 2 2 0 Protocadherin Pkinase PF00069.20 EMD59545.1 - 2.3e-65 220.3 0.0 9e-65 218.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD59545.1 - 4.2e-36 124.3 0.0 1.3e-30 106.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMD59545.1 - 0.00013 21.0 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EMD59545.1 - 0.0068 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMD59545.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.9 EMD59546.1 - 5.8e-27 94.8 1.3 8.5e-27 94.3 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD59546.1 - 1.3e-13 51.1 0.8 1.3e-13 51.1 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EMD59546.1 - 6.8e-13 48.0 0.0 1.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EMD59546.1 - 2.2e-07 31.1 0.0 4.2e-05 23.7 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EMD59546.1 - 5.5e-06 26.5 0.0 2.1e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_7 PF13241.1 EMD59546.1 - 0.0084 16.3 0.4 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EMD59546.1 - 0.033 13.5 0.3 0.28 10.5 0.1 2.4 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EMD59546.1 - 0.041 13.6 0.2 1.6 8.4 0.0 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding Glyco_hydro_31 PF01055.21 EMD59549.1 - 1.7e-167 557.7 5.7 2.2e-167 557.4 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD59549.1 - 0.0024 17.6 3.0 0.0037 17.0 0.1 2.9 4 0 0 4 4 4 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.6 EMD59549.1 - 0.13 11.3 0.1 0.57 9.2 0.0 1.9 2 0 0 2 2 2 0 Rotavirus major outer capsid protein VP7 TraT PF05818.7 EMD59550.1 - 0.037 13.4 3.8 0.064 12.6 2.6 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Sporozoite_P67 PF05642.6 EMD59550.1 - 0.058 11.2 9.3 0.071 10.9 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gly-zipper_Omp PF13488.1 EMD59550.1 - 0.86 9.2 30.1 45 3.7 20.8 2.4 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EMD59550.1 - 1.1 8.8 29.0 2 7.9 19.1 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper DUF4066 PF13278.1 EMD59552.1 - 7.1e-29 100.2 0.0 9.2e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD59552.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Tannase PF07519.6 EMD59553.1 - 1.3e-89 301.1 0.5 1.6e-89 300.8 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EMD59553.1 - 7e-06 25.4 0.0 0.071 12.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMD59553.1 - 0.00033 20.5 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD59553.1 - 0.00068 19.4 1.7 0.033 13.9 1.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD59553.1 - 0.0073 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMD59553.1 - 0.0091 15.4 0.1 0.021 14.2 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Isochorismatase PF00857.15 EMD59554.1 - 3.8e-27 95.3 0.3 1.8e-26 93.0 0.2 1.8 1 1 0 1 1 1 1 Isochorismatase family Flexi_CP_N PF08358.5 EMD59554.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Carlavirus coat Zn_clus PF00172.13 EMD59555.1 - 1.5e-07 31.1 11.4 3.6e-07 29.9 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD59555.1 - 8.7e-07 28.0 0.6 1.4e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD59556.1 - 3.2e-53 180.6 33.5 4.6e-52 176.8 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59556.1 - 1.9e-16 59.7 22.2 5.5e-11 41.6 8.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EMD59556.1 - 2.1e-11 42.7 4.4 3.4e-11 42.0 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EMD59556.1 - 0.00079 18.2 2.4 0.0019 16.9 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 EMD59556.1 - 0.0014 16.8 4.8 0.0014 16.8 3.3 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector FSH1 PF03959.8 EMD59558.1 - 3.1e-26 92.1 0.0 3.6e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMD59558.1 - 0.011 15.6 0.1 0.55 10.0 0.0 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD59558.1 - 0.014 15.1 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family GFO_IDH_MocA_C PF02894.12 EMD59559.1 - 3.1e-18 65.6 0.3 7.5e-18 64.4 0.2 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EMD59559.1 - 4.8e-16 59.3 0.0 1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMD59559.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_10 PF00331.15 EMD59560.1 - 8.8e-96 320.6 0.0 1.1e-95 320.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EMD59560.1 - 9.1e-11 41.2 5.2 2.6e-10 39.7 3.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain CENP-B_dimeris PF09026.5 EMD59560.1 - 0.49 10.6 5.1 2.9 8.1 4.0 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldedh PF00171.17 EMD59561.1 - 3.3e-151 503.7 0.0 4e-151 503.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD59561.1 - 3.4e-06 26.0 0.0 5.4e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1768 PF08719.6 EMD59562.1 - 2.3e-51 173.6 0.2 2.3e-51 173.6 0.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF4360 PF14273.1 EMD59563.1 - 4.3e-43 147.1 0.2 4.9e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Ada3 PF10198.4 EMD59564.1 - 2.1e-40 137.5 0.0 3.8e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Complex1_LYR_2 PF13233.1 EMD59564.1 - 0.069 13.6 0.1 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Complex1_LYR-like zf-RING_2 PF13639.1 EMD59565.1 - 6e-13 48.3 8.3 1.1e-12 47.5 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD59565.1 - 5.3e-06 26.0 5.6 9.5e-06 25.2 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD59565.1 - 1.8e-05 24.6 7.5 3.4e-05 23.7 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD59565.1 - 3.6e-05 23.7 3.4 7.6e-05 22.7 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD59565.1 - 9.5e-05 21.9 7.1 0.00019 21.0 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD59565.1 - 0.00018 21.0 4.3 0.00032 20.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4481 PF14800.1 EMD59565.1 - 0.0011 17.9 0.3 0.0016 17.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) zf-Apc11 PF12861.2 EMD59565.1 - 0.011 15.5 3.5 0.03 14.1 2.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PepSY_TM_2 PF13703.1 EMD59565.1 - 0.092 12.9 0.1 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix zf-RING_4 PF14570.1 EMD59565.1 - 0.1 12.2 4.7 0.2 11.2 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMD59565.1 - 0.25 11.1 6.8 0.71 9.6 4.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EMD59565.1 - 0.93 9.2 4.5 2.3 7.9 3.1 1.7 1 0 0 1 1 1 0 PHD-finger DUF3927 PF13064.1 EMD59565.1 - 2.5 7.6 5.6 4.3 6.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) zf-C3HC4_4 PF15227.1 EMD59565.1 - 7.1 6.5 8.7 17 5.4 6.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RVT_1 PF00078.22 EMD59566.1 - 0.0031 16.8 0.2 0.0031 16.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1186 PF06685.6 EMD59566.1 - 0.061 12.4 2.1 0.059 12.5 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) SpoIIID PF12116.3 EMD59568.1 - 0.0012 18.7 0.5 0.0015 18.4 0.4 1.3 1 1 0 1 1 1 1 Stage III sporulation protein D DNA_topoisoIV PF00521.15 EMD59568.1 - 0.047 12.5 1.0 0.049 12.4 0.7 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Erg28 PF03694.8 EMD59568.1 - 0.09 12.7 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Erg28 like protein HeLo PF14479.1 EMD59571.1 - 7.7e-17 61.7 0.0 1.9e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation RVT_1 PF00078.22 EMD59575.1 - 8e-08 31.8 2.3 8.3e-08 31.8 1.6 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) POT1 PF02765.12 EMD59575.1 - 0.0081 16.0 0.7 0.0086 16.0 0.5 1.1 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 But2 PF09792.4 EMD59578.1 - 2.6e-14 53.1 0.2 3.7e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ABC_membrane_2 PF06472.10 EMD59579.1 - 5.2e-98 327.6 1.0 5.5e-98 327.5 0.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMD59579.1 - 2.5e-15 56.9 0.0 4.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EMD59579.1 - 0.0048 16.8 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EMD59579.1 - 0.022 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.1 EMD59579.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMD59579.1 - 0.025 15.3 0.9 0.38 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EMD59579.1 - 0.031 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EMD59579.1 - 0.037 14.3 1.3 1 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMD59579.1 - 0.038 13.5 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 EMD59579.1 - 0.044 13.9 0.1 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD59579.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EMD59579.1 - 0.065 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMD59579.1 - 0.074 12.8 0.1 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMD59579.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3313 PF11769.3 EMD59580.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DUF1049 PF06305.6 EMD59580.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) HLH PF00010.21 EMD59581.1 - 6.2e-12 45.0 0.1 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NPR2 PF06218.6 EMD59582.1 - 2.5e-146 487.7 0.0 3.5e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EMD59582.1 - 0.0024 16.4 0.2 7.2 5.0 0.0 3.5 3 1 0 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 tRNA-synt_2 PF00152.15 EMD59585.1 - 4.6e-68 229.4 0.0 6e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMD59585.1 - 4.8e-08 32.7 0.0 8.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMD59585.1 - 8.8e-08 31.6 0.1 1.9e-05 23.9 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EMD59585.1 - 0.024 14.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) ADH_N PF08240.7 EMD59587.1 - 1.7e-27 95.2 2.6 4.7e-27 93.8 1.8 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD59587.1 - 2.5e-06 27.0 0.0 0.00074 19.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase FANCL_C PF11793.3 EMD59587.1 - 0.04 13.8 1.1 0.077 12.9 0.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain ADH_N_assoc PF13823.1 EMD59587.1 - 0.06 13.0 0.1 0.06 13.0 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated MBOAT_2 PF13813.1 EMD59588.1 - 7e-14 51.6 9.7 7e-14 51.6 6.8 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Acyl_transf_3 PF01757.17 EMD59590.1 - 9e-20 70.7 25.1 1.1e-19 70.4 17.2 1.3 1 1 0 1 1 1 1 Acyltransferase family 2OG-FeII_Oxy PF03171.15 EMD59591.1 - 0.036 14.3 0.0 0.078 13.2 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 EMD59592.1 - 9.3e-57 191.5 0.6 1.6e-56 190.8 0.4 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EMD59592.1 - 0.00087 19.3 0.1 0.011 15.8 0.0 2.7 1 1 3 4 4 4 1 Fascin domain NAD_binding_1 PF00175.16 EMD59593.1 - 1.9e-31 108.8 0.0 3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMD59593.1 - 1e-21 76.8 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMD59593.1 - 4.7e-07 29.8 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMD59593.1 - 8.1e-05 22.5 0.0 0.00024 21.0 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Sel1 PF08238.7 EMD59594.1 - 1.1e-43 146.6 44.7 3e-07 30.8 0.1 13.3 13 0 0 13 13 13 9 Sel1 repeat TPR_11 PF13414.1 EMD59594.1 - 0.0018 17.9 20.1 0.14 11.8 0.1 6.8 7 2 1 8 8 8 3 TPR repeat OPA3 PF07047.7 EMD59594.1 - 0.037 13.7 0.4 0.08 12.7 0.3 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TPR_8 PF13181.1 EMD59594.1 - 0.086 12.6 2.0 8.2 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMD59594.1 - 0.11 12.4 0.2 0.11 12.4 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD59594.1 - 0.12 12.0 0.0 0.12 12.0 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PulG PF11773.3 EMD59594.1 - 0.17 11.6 1.2 0.39 10.4 0.8 1.6 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin TPR_7 PF13176.1 EMD59594.1 - 0.63 9.9 12.2 0.62 10.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD59594.1 - 0.65 10.0 0.0 0.65 10.0 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat MFS_1 PF07690.11 EMD59595.1 - 1.5e-38 132.4 47.0 2.2e-38 131.8 32.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59595.1 - 9.1e-11 40.9 13.3 9.1e-11 40.9 9.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMD59595.1 - 2.6e-07 29.2 21.2 3.9e-07 28.6 14.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 2TM PF13239.1 EMD59595.1 - 0.0064 16.5 1.3 0.066 13.2 0.9 2.7 2 0 0 2 2 2 1 2TM domain Histidinol_dh PF00815.15 EMD59596.1 - 1.5e-175 583.7 5.8 1.5e-175 583.7 4.1 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EMD59596.1 - 9.4e-26 89.2 0.1 1.8e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EMD59596.1 - 2.2e-11 43.8 0.2 9.3e-11 41.8 0.1 2.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase EHN PF06441.7 EMD59597.1 - 1.4e-38 131.2 0.4 2.6e-38 130.4 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMD59597.1 - 3.5e-07 30.3 0.1 1.1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD59597.1 - 1.6e-06 27.8 0.0 6.1e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Tannase PF07519.6 EMD59598.1 - 3.7e-111 372.1 0.8 4.7e-111 371.8 0.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EMD59598.1 - 0.0072 15.9 1.1 0.061 12.8 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipocalin_5 PF13924.1 EMD59599.1 - 1e-26 93.3 0.0 1.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Sulfate_transp PF00916.15 EMD59600.1 - 7.7e-75 251.4 13.3 1.2e-74 250.8 9.2 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMD59600.1 - 4.3e-30 103.2 2.9 4.3e-30 103.2 2.0 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMD59600.1 - 4.7e-08 32.4 0.0 9.6e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Glyco_hydro_45 PF02015.11 EMD59601.1 - 1.7e-93 312.2 17.3 2e-93 312.0 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Fringe PF02434.11 EMD59602.1 - 4.1e-09 36.0 0.1 4.5e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EMD59602.1 - 0.002 17.8 1.6 0.0041 16.8 1.1 1.4 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 EMD59602.1 - 0.015 14.8 0.0 0.12 11.9 0.0 2.1 1 1 1 2 2 2 0 Galactosyltransferase DUF604 PF04646.7 EMD59602.1 - 0.031 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 SH3_9 PF14604.1 EMD59603.1 - 9.3e-14 50.7 0.1 1.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMD59603.1 - 5e-12 45.0 0.0 1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EMD59603.1 - 1.2e-10 41.0 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EMD59603.1 - 6.5e-08 32.7 0.0 1.8e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMD59603.1 - 1.3e-07 31.8 0.0 3.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EMD59603.1 - 1.7e-07 30.5 0.0 3.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EMD59603.1 - 0.0061 16.7 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EMD59603.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Gastrin PF00918.12 EMD59603.1 - 1.5 9.6 5.6 0.76 10.6 1.0 2.7 2 0 0 2 2 2 0 Gastrin/cholecystokinin family zf-MIZ PF02891.15 EMD59604.1 - 1.4e-10 40.4 0.8 3.1e-10 39.3 0.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Cut12 PF11500.3 EMD59604.1 - 0.68 9.6 3.3 1.3 8.6 2.3 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein zf-RanBP PF00641.13 EMD59604.1 - 3.5 6.8 5.6 3.6 6.7 0.4 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AT_hook PF02178.14 EMD59604.1 - 4.7 7.2 10.4 0.38 10.5 1.6 2.7 2 0 0 2 2 2 0 AT hook motif SprT-like PF10263.4 EMD59605.1 - 4.5e-05 23.1 0.2 0.00015 21.4 0.1 1.8 1 1 0 1 1 1 1 SprT-like family Peptidase_M50B PF13398.1 EMD59605.1 - 0.11 11.9 0.3 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like MRI PF15325.1 EMD59607.1 - 0.023 15.6 1.0 0.068 14.1 0.5 1.9 1 1 0 1 1 1 0 Modulator of retrovirus infection RRM_1 PF00076.17 EMD59607.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_16 PF00722.16 EMD59608.1 - 1.6e-41 141.6 3.3 2.7e-41 140.8 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl-CoA_dh_1 PF00441.19 EMD59609.1 - 4.3e-39 134.0 6.4 6.5e-39 133.4 4.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD59609.1 - 6.4e-30 104.0 0.4 1.7e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMD59609.1 - 2.5e-17 62.1 0.0 4.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD59609.1 - 2e-14 53.9 3.5 3.1e-14 53.3 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EMD59609.1 - 0.0023 17.3 0.5 0.012 14.9 0.1 2.2 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TPR_MLP1_2 PF07926.7 EMD59610.1 - 2.5e-05 24.0 98.9 0.017 14.8 15.3 6.1 2 1 4 6 6 6 5 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EMD59610.1 - 0.00011 20.1 90.2 0.00011 20.1 62.5 3.3 2 1 0 2 2 2 1 Myosin tail Filament PF00038.16 EMD59610.1 - 0.00012 21.7 84.3 0.33 10.3 34.7 5.3 2 1 2 4 4 4 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 EMD59610.1 - 0.00023 21.0 105.1 0.00024 20.9 13.8 6.3 2 1 3 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EMD59610.1 - 0.00035 19.8 90.1 0.044 12.9 9.6 7.2 2 1 4 7 7 7 4 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EMD59610.1 - 0.00037 20.4 10.1 0.00037 20.4 7.0 7.6 3 1 4 8 8 8 3 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 EMD59610.1 - 0.00039 19.8 15.7 0.00039 19.8 10.9 6.6 2 1 5 7 7 7 1 Domain of unknown function (DUF4201) DUF4200 PF13863.1 EMD59610.1 - 0.0009 19.1 12.9 0.0009 19.1 8.9 7.1 2 1 4 6 6 6 2 Domain of unknown function (DUF4200) IncA PF04156.9 EMD59610.1 - 0.0015 18.1 107.5 0.093 12.3 15.4 7.2 2 1 5 7 7 7 5 IncA protein APG6 PF04111.7 EMD59610.1 - 0.0079 15.2 98.6 0.052 12.5 11.7 6.6 2 1 5 7 7 7 4 Autophagy protein Apg6 BLOC1_2 PF10046.4 EMD59610.1 - 0.0094 16.0 2.4 0.0094 16.0 1.7 6.7 2 1 6 8 8 7 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EMD59610.1 - 0.016 14.4 48.4 0.13 11.4 4.3 4.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DMPK_coil PF08826.5 EMD59610.1 - 0.017 15.0 1.2 0.017 15.0 0.9 9.3 6 4 2 9 9 7 0 DMPK coiled coil domain like ATG16 PF08614.6 EMD59610.1 - 0.028 14.2 95.2 0.12 12.1 7.1 6.6 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EMD59610.1 - 0.17 10.2 66.6 0.063 11.7 16.4 3.9 2 1 2 4 4 4 0 AAA domain DUF3450 PF11932.3 EMD59610.1 - 1.3 8.2 72.0 0.089 12.0 3.8 6.8 2 1 4 6 6 6 0 Protein of unknown function (DUF3450) LRR_8 PF13855.1 EMD59611.1 - 1.2e-12 47.3 7.0 0.0033 17.1 0.0 4.2 1 1 5 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMD59611.1 - 1.3e-11 43.8 7.2 0.016 14.8 0.0 5.2 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMD59611.1 - 4e-11 41.3 10.0 0.7 10.1 0.0 8.2 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.1 EMD59611.1 - 1.2e-06 27.9 0.1 0.51 10.5 0.0 5.9 5 1 1 6 6 6 1 Leucine Rich repeat SAM_PNT PF02198.11 EMD59611.1 - 0.001 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain LRR_7 PF13504.1 EMD59611.1 - 0.0011 18.8 0.7 25 5.6 0.0 5.9 5 1 2 7 7 7 0 Leucine rich repeat LRRNT_2 PF08263.7 EMD59611.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Pkinase PF00069.20 EMD59612.1 - 2.5e-10 39.9 0.1 2.8e-08 33.2 0.0 2.0 1 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 EMD59612.1 - 0.029 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_2 PF00891.13 EMD59613.1 - 1e-29 103.4 0.0 4.1e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 EMD59613.1 - 0.011 16.3 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMD59613.1 - 0.039 13.6 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pro_isomerase PF00160.16 EMD59615.1 - 8.1e-30 104.0 0.0 1.3e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EMD59615.1 - 1.6e-15 56.4 0.0 3.8e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD59615.1 - 9.3e-11 41.5 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD59615.1 - 5.6e-09 35.7 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD59615.1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Kelch_4 PF13418.1 EMD59616.1 - 1e-26 92.4 11.6 1.9e-08 33.8 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD59616.1 - 3e-26 90.8 3.2 3.1e-07 30.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EMD59616.1 - 6.9e-26 89.3 4.8 8.5e-07 28.8 0.2 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EMD59616.1 - 9.1e-23 79.5 1.8 8.6e-06 25.2 0.2 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EMD59616.1 - 2.1e-20 72.2 17.9 2.8e-08 33.7 0.0 6.0 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EMD59616.1 - 8.2e-17 60.2 2.9 5.3e-05 22.8 0.1 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EMD59616.1 - 8.8e-09 35.3 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EMD59616.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 EMD59617.1 - 8.2e-24 82.5 10.5 1.7e-05 24.5 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD59617.1 - 5.9e-06 26.1 1.8 0.0031 17.2 0.0 2.9 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleos_tra2_C PF07662.8 EMD59618.1 - 2.9e-67 226.1 0.0 2.9e-67 226.1 0.0 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EMD59618.1 - 3.8e-23 81.6 3.8 3.8e-23 81.6 2.7 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Bromodomain PF00439.20 EMD59619.1 - 1.1e-23 82.9 1.3 1.9e-23 82.1 0.9 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EMD59619.1 - 9.1e-10 38.5 0.1 2e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD59619.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 EMD59620.1 - 4.2e-90 301.2 0.1 4.9e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TFIIA PF03153.8 EMD59621.1 - 8.9e-67 226.5 26.3 1.1e-66 226.3 18.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.16 EMD59622.1 - 0.0027 17.6 2.6 0.0059 16.5 1.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EMD59622.1 - 0.022 14.3 0.2 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CheR_N PF03705.10 EMD59622.1 - 0.028 13.7 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain Viral_NABP PF05515.6 EMD59622.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral nucleic acid binding PAF-AH_p_II PF03403.8 EMD59623.1 - 7.5e-50 169.3 0.0 4.7e-26 90.9 0.0 3.1 2 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMD59623.1 - 5.5e-10 39.1 0.6 4.2e-09 36.3 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD59623.1 - 1.3e-05 25.2 0.0 5.7e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD59623.1 - 1.4e-05 24.1 0.0 0.00063 18.7 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMD59623.1 - 0.00096 18.0 0.0 0.0025 16.6 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EMD59623.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Metallophos PF00149.23 EMD59624.1 - 4.3e-08 32.7 0.0 5.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD59624.1 - 3e-05 23.9 0.0 9.3e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hamartin PF04388.7 EMD59625.1 - 1.7 7.2 14.5 2.3 6.7 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein Zip PF02535.17 EMD59625.1 - 4.9 6.0 7.0 7.8 5.3 4.8 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Thg1C PF14413.1 EMD59626.1 - 2e-52 176.0 0.0 2.3e-44 149.9 0.0 3.0 3 0 0 3 3 3 2 Thg1 C terminal domain Thg1 PF04446.7 EMD59626.1 - 4.8e-45 152.5 0.0 7.4e-45 151.8 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Sugar_tr PF00083.19 EMD59630.1 - 3.3e-106 355.5 24.2 3.8e-106 355.3 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59630.1 - 7.7e-27 93.9 28.8 3.5e-19 68.7 2.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.26 EMD59631.1 - 1.3e-08 34.4 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain AA_permease_2 PF13520.1 EMD59633.1 - 7.5e-51 172.9 49.6 9.4e-51 172.6 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD59633.1 - 1.7e-23 82.7 40.6 2.2e-23 82.3 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease Dpy19 PF10034.4 EMD59633.1 - 0.027 12.6 2.7 0.041 12.0 1.9 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF3593 PF12159.3 EMD59633.1 - 0.088 12.5 2.6 0.34 10.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) GFA PF04828.9 EMD59634.1 - 0.0032 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FMO-like PF00743.14 EMD59635.1 - 5.7e-62 209.6 0.0 8.9e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMD59635.1 - 4.5e-28 98.7 0.1 8.5e-26 91.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD59635.1 - 2.6e-12 47.0 0.0 5.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD59635.1 - 1e-08 34.5 0.4 1.2e-06 27.7 0.3 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD59635.1 - 1.7e-08 34.3 0.7 2.7e-06 27.2 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EMD59635.1 - 3.9e-05 22.7 0.0 0.66 8.8 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD59635.1 - 0.00023 19.7 0.1 0.29 9.5 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EMD59635.1 - 0.00029 20.7 0.0 0.00091 19.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.7 EMD59635.1 - 0.017 14.4 0.0 0.23 10.8 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 EMD59637.1 - 3.3e-37 128.0 28.0 3.3e-37 128.0 19.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0542 PF15086.1 EMD59637.1 - 0.22 11.2 0.9 0.74 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PepSY_TM_1 PF13172.1 EMD59637.1 - 1.8 8.4 7.9 0.18 11.5 0.2 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix Cellulase PF00150.13 EMD59638.1 - 2.5e-17 63.0 3.2 7.3e-17 61.4 2.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EMD59639.1 - 1.2e-56 191.9 55.1 2.5e-44 151.4 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD59639.1 - 0.00025 20.7 4.2 0.053 13.3 0.0 3.7 4 0 0 4 4 4 2 MFS_1 like family DUF1500 PF07389.7 EMD59639.1 - 0.046 13.7 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) Chal_sti_synt_N PF00195.14 EMD59640.1 - 9e-29 100.3 0.0 1.6e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EMD59640.1 - 2.1e-18 66.6 0.0 4.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 EMD59640.1 - 3.9e-09 36.3 0.1 3.1e-07 30.3 0.0 2.9 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.7 EMD59640.1 - 3.8e-07 29.4 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 EMD59640.1 - 7.7e-05 22.2 1.6 0.00022 20.8 1.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TPR_12 PF13424.1 EMD59642.1 - 3.9e-21 74.7 9.9 2.4e-07 30.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMD59642.1 - 6.4e-20 70.3 17.6 3.6e-06 26.7 0.0 6.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD59642.1 - 8.6e-11 42.2 4.6 3.8e-05 24.2 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMD59642.1 - 9.6e-10 38.4 11.0 0.022 14.8 0.1 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD59642.1 - 2.4e-09 37.3 9.3 0.11 12.8 0.1 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD59642.1 - 1.7e-08 34.3 10.5 0.42 11.3 0.0 5.3 3 1 2 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD59642.1 - 5.6e-08 32.8 2.1 0.0081 16.2 0.1 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EMD59642.1 - 2.4e-07 30.9 0.0 7.9e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMD59642.1 - 2.7e-07 29.7 0.1 4.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EMD59642.1 - 0.00011 22.1 0.1 9.6 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD59642.1 - 0.00022 20.8 6.3 5.7 7.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD59642.1 - 0.0012 18.4 8.0 1 9.3 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat NACHT PF05729.7 EMD59642.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TPR_6 PF13174.1 EMD59642.1 - 0.017 15.5 4.2 46 4.7 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 EMD59642.1 - 0.029 13.6 0.3 6 6.2 0.0 3.6 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat Foie-gras_1 PF11817.3 EMD59642.1 - 0.041 13.3 1.9 9.8 5.5 0.0 3.5 2 1 2 4 4 4 0 Foie gras liver health family 1 TPR_8 PF13181.1 EMD59642.1 - 0.058 13.2 0.0 29 4.7 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMD59642.1 - 1.6 9.3 0.0 1.6 9.3 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF1446 PF07287.6 EMD59643.1 - 6.2e-130 432.8 1.2 8.2e-130 432.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) zf-CCHC_6 PF15288.1 EMD59644.1 - 0.037 13.6 0.3 0.08 12.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DctQ PF04290.7 EMD59644.1 - 0.18 11.5 9.4 0.18 11.5 4.4 2.2 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component RE_XamI PF09572.5 EMD59645.1 - 0.012 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease LELP1 PF15042.1 EMD59645.1 - 0.66 10.1 14.5 0.11 12.6 7.5 1.6 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Methyltransf_23 PF13489.1 EMD59647.1 - 1.9e-19 69.9 0.0 2.6e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD59647.1 - 1.1e-06 28.9 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD59647.1 - 2.9e-06 27.6 0.0 1.8e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD59647.1 - 3.1e-06 27.7 0.1 2.3e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD59647.1 - 3.3e-05 23.5 0.0 0.00022 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD59647.1 - 0.0017 18.6 0.0 0.012 15.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMD59647.1 - 0.0083 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMD59647.1 - 0.0089 16.0 0.0 0.021 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMD59647.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EMD59647.1 - 0.046 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EMD59647.1 - 0.057 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SBF PF01758.11 EMD59648.1 - 5.8e-48 162.7 8.6 5.8e-48 162.7 6.0 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family HLH PF00010.21 EMD59650.1 - 1.8e-12 46.7 0.1 1.8e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.10 EMD59650.1 - 0.045 13.5 1.3 0.045 13.5 0.9 2.2 2 0 0 2 2 2 0 Basic region leucine zipper KLRAQ PF10205.4 EMD59650.1 - 0.71 9.9 5.3 1.7 8.6 0.3 2.9 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein zf-RING_2 PF13639.1 EMD59651.1 - 3.7e-13 49.0 5.7 3.7e-13 49.0 4.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMD59651.1 - 2.5e-09 36.6 3.2 2.5e-09 36.6 2.3 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD59651.1 - 3.3e-08 33.5 6.7 7.2e-08 32.4 4.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD59651.1 - 5e-07 29.6 3.2 5e-07 29.6 2.2 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD59651.1 - 6.3e-06 25.8 3.5 1.1e-05 25.0 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD59651.1 - 8.8e-06 25.2 1.1 1.5e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD59651.1 - 0.0001 22.0 4.1 0.00019 21.1 2.8 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMD59651.1 - 0.0026 17.7 5.7 0.005 16.8 2.0 2.2 1 1 1 2 2 2 1 RING-variant domain TMEM154 PF15102.1 EMD59651.1 - 0.0063 16.2 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family FANCL_C PF11793.3 EMD59651.1 - 0.0081 16.0 10.4 0.089 12.7 5.1 2.9 1 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EMD59651.1 - 0.037 13.9 1.8 0.037 13.9 1.2 1.8 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Cytochrome_CBB3 PF13442.1 EMD59651.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III SKG6 PF08693.5 EMD59651.1 - 0.1 11.9 2.9 0.18 11.1 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PHD PF00628.24 EMD59651.1 - 0.13 11.9 4.9 0.24 11.1 3.4 1.5 1 0 0 1 1 1 0 PHD-finger DUF3377 PF11857.3 EMD59651.1 - 0.16 11.6 0.7 0.44 10.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Prok-RING_4 PF14447.1 EMD59651.1 - 0.24 10.9 4.2 0.54 9.8 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EMD59651.1 - 0.28 10.8 5.2 0.52 9.9 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain COX6B PF02297.12 EMD59651.1 - 0.72 9.9 4.2 2.1 8.3 0.3 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb zf-RING-like PF08746.6 EMD59651.1 - 1 9.4 5.3 2 8.5 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-MIZ PF02891.15 EMD59651.1 - 2.7 7.5 5.9 7 6.2 4.1 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Bul1_N PF04425.7 EMD59654.1 - 1.6e-08 33.5 1.1 1e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 EMD59654.1 - 5.7e-06 25.7 0.1 1.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EMD59654.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Tmemb_14 PF03647.8 EMD59655.1 - 1.5e-26 92.5 2.4 1.7e-26 92.4 1.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.16 EMD59655.1 - 0.12 12.2 0.1 0.12 12.2 0.0 2.7 4 0 0 4 4 4 0 Gram positive anchor p450 PF00067.17 EMD59656.1 - 1.3e-33 116.2 0.0 1.7e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phageshock_PspD PF09584.5 EMD59656.1 - 0.015 14.9 0.7 0.035 13.8 0.0 2.0 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) p450 PF00067.17 EMD59657.1 - 6.7e-26 90.8 0.1 5.9e-16 58.0 0.1 2.3 1 1 1 2 2 2 2 Cytochrome P450 HATPase_c PF02518.21 EMD59658.1 - 4.7e-23 81.0 0.0 8.9e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD59658.1 - 2.5e-19 69.3 0.1 9.1e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EMD59658.1 - 2.3e-13 50.4 0.0 7.1e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EMD59658.1 - 1.6e-09 37.7 0.0 1e-07 31.9 0.0 3.0 3 0 0 3 3 3 1 PAS fold HisKA PF00512.20 EMD59658.1 - 1.1e-07 31.7 2.0 1.8e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EMD59658.1 - 1.7e-05 24.5 0.0 0.0006 19.5 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EMD59658.1 - 6.2e-05 22.7 0.0 0.0002 21.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EMD59658.1 - 0.00031 20.7 0.2 0.00091 19.2 0.1 1.9 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 EMD59658.1 - 0.076 13.4 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 GAF domain Glyco_hydro_52 PF03512.8 EMD59658.1 - 0.38 9.3 0.0 9.8 4.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 WW PF00397.21 EMD59659.1 - 1.4e-08 34.4 4.8 3e-08 33.3 3.3 1.6 1 0 0 1 1 1 1 WW domain UDG PF03167.14 EMD59660.1 - 3.6e-19 68.7 0.0 5.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DIT1_PvcA PF05141.7 EMD59663.1 - 9.5e-77 258.0 0.0 1.2e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein HATPase_c PF02518.21 EMD59664.1 - 7.6e-23 80.3 0.0 1.8e-21 75.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD59664.1 - 1.6e-22 79.6 1.2 5e-22 78.0 0.8 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMD59664.1 - 3.5e-09 36.5 0.1 1.1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EMD59664.1 - 7.8e-09 35.5 0.0 7.7e-07 29.1 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EMD59664.1 - 1.1e-06 28.9 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EMD59664.1 - 2.9e-06 27.0 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 EMD59664.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.1 EMD59664.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain AJAP1_PANP_C PF15298.1 EMD59664.1 - 0.017 14.9 0.2 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF1788 PF08747.6 EMD59664.1 - 0.14 11.9 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) F-box PF00646.28 EMD59665.1 - 3.1e-12 45.8 0.2 1.2e-11 43.8 0.2 2.1 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 EMD59665.1 - 1.4e-10 40.6 0.2 1.3e-08 34.3 0.2 2.3 1 1 1 2 2 2 2 TPR repeat F-box-like PF12937.2 EMD59665.1 - 1.5e-07 30.9 0.3 3.2e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMD59665.1 - 5.6e-07 29.0 7.0 0.017 14.7 0.0 5.2 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 EMD59665.1 - 1.5e-06 27.7 2.4 0.00052 19.7 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD59665.1 - 1.6e-05 24.3 0.9 0.0034 16.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD59665.1 - 0.00094 19.0 0.5 0.0097 15.8 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat LRR_8 PF13855.1 EMD59665.1 - 0.0025 17.5 2.3 1.3 8.7 0.0 4.6 5 0 0 5 5 5 1 Leucine rich repeat DUF4477 PF14780.1 EMD59665.1 - 0.0029 17.0 0.2 0.4 10.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) LRR_6 PF13516.1 EMD59665.1 - 0.0085 16.0 3.6 0.39 10.9 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich repeat TPR_6 PF13174.1 EMD59665.1 - 0.034 14.5 0.6 1.3 9.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD59665.1 - 0.038 14.6 0.0 1.8 9.4 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat PRANC PF09372.5 EMD59665.1 - 0.13 12.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 PRANC domain TPR_8 PF13181.1 EMD59665.1 - 0.16 11.8 1.8 0.29 11.0 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.28 EMD59665.1 - 1.2 9.4 6.3 28 5.2 0.0 5.2 6 0 0 6 6 5 0 Leucine Rich Repeat RNA_pol_Rpb2_6 PF00562.23 EMD59666.1 - 9.3e-124 413.0 0.1 1.7e-123 412.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMD59666.1 - 1e-60 204.1 0.0 1.7e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMD59666.1 - 1.3e-41 142.1 0.8 2.4e-41 141.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMD59666.1 - 3e-29 101.0 0.0 6.3e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EMD59666.1 - 4.3e-23 80.8 0.0 9.5e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EMD59666.1 - 2.3e-22 78.5 0.4 5.4e-22 77.3 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EMD59666.1 - 6.1e-20 70.9 0.1 1.5e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.6 EMD59666.1 - 0.19 11.4 0.2 0.44 10.2 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ubiquitin PF00240.18 EMD59667.1 - 5.9e-18 64.0 0.0 9.9e-18 63.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMD59667.1 - 7e-09 35.2 0.0 7e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EMD59667.1 - 1.9e-06 27.4 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD59667.1 - 4.2e-05 23.6 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMD59667.1 - 0.00023 21.0 0.1 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EMD59667.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ADH_zinc_N PF00107.21 EMD59668.1 - 3.4e-34 117.1 0.2 6.8e-34 116.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD59668.1 - 3.5e-08 34.3 0.0 7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD59668.1 - 1.8e-06 27.6 0.0 5.5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMD59668.1 - 0.0054 16.3 1.2 0.022 14.3 0.6 2.0 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMD59668.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EMD59669.1 - 9.5e-15 54.9 0.0 5.6e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EMD59669.1 - 9.7e-09 35.0 0.1 1.8e-08 34.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMD59669.1 - 3.2e-05 22.9 0.0 4.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 EMD59669.1 - 0.0055 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyoxalase_2 PF12681.2 EMD59670.1 - 5.1e-09 36.7 0.3 5.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EMD59670.1 - 6e-09 35.9 0.7 3.7e-07 30.1 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily S1-P1_nuclease PF02265.11 EMD59671.1 - 9.5e-62 208.8 0.1 1.1e-61 208.6 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Integrase_DNA PF02920.10 EMD59671.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase A_deaminase PF00962.17 EMD59672.1 - 4.4e-45 154.0 0.0 6.7e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.1 EMD59673.1 - 4.2e-43 146.6 0.0 8.9e-43 145.5 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EMD59673.1 - 6.4e-25 87.1 0.0 1.5e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain MFS_1 PF07690.11 EMD59674.1 - 1.8e-38 132.1 30.6 2.7e-38 131.6 21.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UQ_con PF00179.21 EMD59677.1 - 7.2e-49 164.8 0.1 8.2e-49 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EMD59677.1 - 0.0081 15.8 0.1 0.012 15.2 0.1 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EMD59677.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EMD59677.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain IL3 PF02059.10 EMD59679.1 - 0.033 14.1 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Interleukin-3 DUF2237 PF09996.4 EMD59680.1 - 8.7e-30 102.6 0.0 1.4e-29 101.9 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF155 PF02582.9 EMD59681.1 - 7.2e-62 208.3 0.0 1.1e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RGS PF00615.14 EMD59682.1 - 1.8e-13 50.6 0.0 2.5e-10 40.4 0.0 2.3 2 1 0 2 2 2 2 Regulator of G protein signaling domain 2OG-FeII_Oxy_3 PF13640.1 EMD59683.1 - 7.4e-10 39.2 0.1 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMD59683.1 - 0.00022 20.7 0.1 0.00039 20.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_Rpb1_1 PF04997.7 EMD59684.1 - 6.4e-107 357.7 0.0 1.2e-106 356.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EMD59684.1 - 9.4e-104 346.5 0.1 1.9e-103 345.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMD59684.1 - 3.4e-70 235.3 0.0 6.6e-70 234.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EMD59684.1 - 8.7e-54 182.1 0.3 1.8e-53 181.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EMD59684.1 - 1.5e-49 167.7 0.0 3.3e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EMD59684.1 - 4.5e-42 142.9 7.2 9.7e-42 141.8 5.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EMD59684.1 - 4.6e-33 113.1 0.0 1.2e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EMD59684.1 - 2e-14 52.3 188.7 0.005 16.8 6.1 13.4 10 3 4 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat NosL PF05573.7 EMD59684.1 - 0.055 13.1 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NosL WD40 PF00400.27 EMD59685.1 - 2.7e-13 49.2 8.7 5.8e-07 29.1 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMD59685.1 - 0.0032 15.8 0.2 0.18 10.0 0.0 2.6 1 1 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EMD59685.1 - 0.0041 16.8 0.1 4.7 6.8 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EMD59685.1 - 0.0045 16.4 0.1 0.6 9.5 0.0 2.6 1 1 2 3 3 3 1 PQQ-like domain INO80_Ies4 PF08193.6 EMD59686.1 - 4.1e-37 128.3 15.4 4.9e-37 128.0 10.7 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 EMD59687.1 - 8.3e-37 126.0 0.1 1.9e-36 124.9 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EMD59687.1 - 3.5e-25 88.4 0.1 5.7e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EMD59687.1 - 0.018 14.7 0.3 0.057 13.2 0.0 2.0 2 0 0 2 2 2 0 LisH Hydrolase PF00702.21 EMD59687.1 - 0.035 14.5 0.6 0.097 13.0 0.2 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PP2C PF00481.16 EMD59688.1 - 8.2e-32 110.5 0.0 2.4e-31 109.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMD59688.1 - 0.0075 15.9 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Esterase_phd PF10503.4 EMD59690.1 - 1.4e-16 60.4 0.7 1.8e-16 60.0 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EMD59690.1 - 8.7e-06 25.5 0.3 1.1e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD59690.1 - 9.1e-06 25.7 0.2 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD59690.1 - 5.1e-05 22.5 0.6 0.00011 21.4 0.2 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMD59690.1 - 0.00077 19.0 0.1 0.00098 18.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EMD59690.1 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.3 EMD59690.1 - 0.003 17.3 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BAAT_C PF08840.6 EMD59690.1 - 0.0046 16.6 0.3 0.0074 16.0 0.2 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EMD59690.1 - 0.029 13.8 0.3 0.041 13.2 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EMD59690.1 - 0.072 12.5 0.1 1.3 8.3 0.0 2.2 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Zip PF02535.17 EMD59691.1 - 0.041 12.8 0.1 0.041 12.8 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1049 PF06305.6 EMD59691.1 - 0.057 12.9 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ArsB PF02040.10 EMD59692.1 - 1.7e-15 56.9 17.2 1.9e-11 43.5 3.4 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Metaviral_G PF09595.5 EMD59693.1 - 0.39 10.3 11.0 0.44 10.1 7.6 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF4228 PF14009.1 EMD59693.1 - 1.7 8.7 17.7 1.9 8.5 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF1510 PF07423.6 EMD59693.1 - 1.9 7.8 17.7 2 7.7 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Otopetrin PF03189.8 EMD59693.1 - 8.2 5.2 8.6 10 5.0 6.0 1.0 1 0 0 1 1 1 0 Otopetrin Response_reg PF00072.19 EMD59694.1 - 1.6e-25 89.2 0.1 2.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMD59694.1 - 1.7e-24 85.6 0.0 4.3e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD59694.1 - 1.1e-13 50.9 0.0 3.7e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EMD59694.1 - 5.7e-05 23.2 2.8 0.19 11.9 0.0 3.7 4 0 0 4 4 4 2 HAMP domain SNF2_N PF00176.18 EMD59695.1 - 1.3e-72 244.1 0.5 1.8e-72 243.6 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMD59695.1 - 2.8e-10 40.3 0.0 7.6e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EMD59695.1 - 2.5e-09 36.6 3.8 6.1e-09 35.4 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD59695.1 - 5.5e-09 35.9 5.3 5.5e-09 35.9 3.7 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EMD59695.1 - 8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EMD59695.1 - 7.4e-07 28.7 4.5 5.1e-06 26.1 2.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMD59695.1 - 8e-07 28.7 5.7 1.8e-06 27.6 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD59695.1 - 1.1e-06 28.2 6.7 2.8e-06 26.8 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD59695.1 - 6.2e-05 22.6 4.4 0.00017 21.2 3.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain SPT6_acidic PF14632.1 EMD59695.1 - 0.00038 20.5 13.0 0.0017 18.5 9.0 2.2 1 0 0 1 1 1 1 Acidic N-terminal SPT6 zf-C3HC4_4 PF15227.1 EMD59695.1 - 0.0014 18.4 7.2 0.0044 16.8 5.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD_2 PF06733.10 EMD59695.1 - 0.008 15.5 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 DEAD_2 AAA_22 PF13401.1 EMD59695.1 - 0.022 14.9 0.1 8.7 6.4 0.0 2.9 1 1 1 2 2 2 0 AAA domain Baculo_IE-1 PF05290.6 EMD59695.1 - 0.075 12.7 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Transposase_1 PF01359.13 EMD59695.1 - 0.09 12.5 1.7 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Transposase (partial DDE domain) CDC45 PF02724.9 EMD59695.1 - 0.27 9.2 7.6 0.47 8.4 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Zn_Tnp_IS1595 PF12760.2 EMD59695.1 - 0.45 10.3 3.3 1.4 8.8 1.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FYVE PF01363.16 EMD59695.1 - 3.3 7.6 6.4 2.3 8.2 1.0 2.6 1 1 1 2 2 2 0 FYVE zinc finger HAMP PF00672.20 EMD59696.1 - 1.1e-43 147.2 23.0 6.9e-10 38.9 0.2 7.0 6 0 0 6 6 6 6 HAMP domain Response_reg PF00072.19 EMD59696.1 - 8.1e-29 99.8 0.5 6.4e-27 93.7 0.1 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EMD59696.1 - 1e-28 99.2 0.3 4.2e-28 97.2 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD59696.1 - 1.8e-17 63.0 0.7 1.8e-17 63.0 0.5 3.7 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EMD59696.1 - 0.0043 15.5 16.7 0.035 12.5 0.5 4.0 2 1 1 4 4 4 3 AAA domain DUF4279 PF14106.1 EMD59696.1 - 0.0058 16.5 1.6 12 5.8 0.0 5.3 6 0 0 6 6 6 1 Domain of unknown function (DUF4279) DUF883 PF05957.8 EMD59696.1 - 0.022 15.1 14.6 4.7 7.6 0.3 6.3 4 1 0 6 6 6 0 Bacterial protein of unknown function (DUF883) Pox_A_type_inc PF04508.7 EMD59696.1 - 0.069 12.9 4.6 0.085 12.6 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NAAA-beta PF15508.1 EMD59696.1 - 0.12 12.6 6.1 7.3 7.0 0.1 5.7 4 2 2 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 EMD59696.1 - 0.21 11.4 17.1 9.8 6.0 0.1 6.3 5 2 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) PilJ PF13675.1 EMD59696.1 - 1.5 9.1 11.1 22 5.4 0.1 5.8 3 2 3 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4543 PF15076.1 EMD59697.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) DUF2452 PF10504.4 EMD59697.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) MSP1_C PF07462.6 EMD59697.1 - 6.2 5.0 5.4 10 4.3 3.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nsp1_C PF05064.8 EMD59698.1 - 8.6e-33 112.4 6.5 8.6e-33 112.4 4.5 2.6 2 1 0 2 2 2 1 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 EMD59698.1 - 0.0038 17.0 16.8 0.024 14.4 10.6 2.4 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 EMD59698.1 - 0.0059 16.3 12.1 0.16 11.7 1.9 3.0 1 1 2 3 3 3 2 Laminin Domain II WXG100 PF06013.7 EMD59698.1 - 0.006 16.5 14.1 0.13 12.3 0.2 4.0 3 1 1 4 4 4 2 Proteins of 100 residues with WXG DUF2813 PF11398.3 EMD59698.1 - 0.0062 15.6 5.1 0.0075 15.3 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) Syntaxin PF00804.20 EMD59698.1 - 0.0066 16.5 13.3 0.38 10.9 6.9 2.9 1 1 0 1 1 1 1 Syntaxin Sin3_corepress PF08295.7 EMD59698.1 - 0.02 14.6 0.9 0.02 14.6 0.6 2.3 2 0 0 2 2 2 0 Sin3 family co-repressor V_ATPase_I PF01496.14 EMD59698.1 - 0.042 11.7 7.7 0.055 11.3 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3829 PF12889.2 EMD59698.1 - 0.048 12.8 8.0 0.067 12.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) EzrA PF06160.7 EMD59698.1 - 0.051 11.7 16.3 0.31 9.1 1.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EMD59698.1 - 0.059 12.5 3.9 0.81 8.8 0.6 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CagA PF03507.8 EMD59698.1 - 0.066 13.0 0.8 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 CagA exotoxin Myosin_tail_1 PF01576.14 EMD59698.1 - 0.071 10.8 17.2 0.14 9.8 11.9 1.4 1 1 0 1 1 1 0 Myosin tail AAA_13 PF13166.1 EMD59698.1 - 0.081 11.3 12.9 0.011 14.2 3.5 1.9 1 1 1 2 2 2 0 AAA domain Peptidase_S64 PF08192.6 EMD59698.1 - 0.09 11.0 4.8 0.11 10.8 3.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 ATG16 PF08614.6 EMD59698.1 - 0.1 12.4 16.0 0.44 10.3 2.3 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MIS13 PF08202.6 EMD59698.1 - 0.1 11.6 11.3 0.13 11.2 7.8 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family ParB PF08775.5 EMD59698.1 - 0.21 11.8 8.2 0.059 13.6 0.8 2.6 2 1 1 3 3 3 0 ParB family Syntaxin-6_N PF09177.6 EMD59698.1 - 0.27 11.6 11.8 1 9.7 1.4 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Laminin_I PF06008.9 EMD59698.1 - 0.31 10.2 17.7 0.33 10.2 3.4 2.7 1 1 2 3 3 3 0 Laminin Domain I Vac_Fusion PF02346.11 EMD59698.1 - 0.32 10.4 2.3 9 5.7 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF3166 PF11365.3 EMD59698.1 - 0.33 11.4 7.0 10 6.6 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) FH2 PF02181.18 EMD59698.1 - 0.36 9.6 7.7 2.6 6.8 1.2 2.5 2 1 1 3 3 3 0 Formin Homology 2 Domain DUF1664 PF07889.7 EMD59698.1 - 0.39 10.5 7.5 2.3 8.0 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 EMD59698.1 - 0.48 9.4 16.8 2.5 7.1 1.7 2.2 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.3 EMD59698.1 - 0.56 7.4 14.9 0.85 6.8 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EMD59698.1 - 0.65 10.0 19.5 0.23 11.4 1.1 3.4 2 1 0 3 3 3 0 Flagellar FliJ protein Fib_alpha PF08702.5 EMD59698.1 - 0.71 9.9 11.2 1.7 8.7 1.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.6 EMD59698.1 - 0.77 9.5 11.9 1.5 8.7 5.5 2.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2408 PF10303.4 EMD59698.1 - 0.84 9.7 8.5 1 9.4 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.7 EMD59698.1 - 0.87 9.4 9.5 11 5.8 6.6 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 EMD59698.1 - 1 9.2 20.9 0.86 9.5 4.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EMD59698.1 - 1.1 9.6 13.5 0.64 10.3 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) End3 PF12761.2 EMD59698.1 - 1.1 8.8 10.9 0.46 10.1 1.5 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 EMD59698.1 - 1.3 7.9 19.5 3.4 6.6 2.4 2.1 1 1 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EMD59698.1 - 1.6 8.9 12.8 0.54 10.4 1.5 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ING PF12998.2 EMD59698.1 - 1.6 9.0 13.4 1.8 8.8 2.8 3.0 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Dynamin_N PF00350.18 EMD59698.1 - 1.8 8.3 6.0 15 5.3 4.2 2.2 1 1 0 1 1 1 0 Dynamin family TPD52 PF04201.10 EMD59698.1 - 2 8.0 8.4 0.91 9.2 0.6 2.4 1 1 1 2 2 2 0 Tumour protein D52 family Taxilin PF09728.4 EMD59698.1 - 2.1 7.3 16.8 50 2.8 11.6 2.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein LOH1CR12 PF10158.4 EMD59698.1 - 2.1 8.1 7.8 27 4.5 3.8 2.9 1 1 1 2 2 2 0 Tumour suppressor protein Streptin-Immun PF11083.3 EMD59698.1 - 2.2 8.3 10.2 1 9.3 1.5 3.1 2 2 0 2 2 2 0 Lantibiotic streptin immunity protein Spc7 PF08317.6 EMD59698.1 - 2.2 6.8 16.1 0.58 8.7 3.1 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.6 EMD59698.1 - 2.4 8.0 7.5 2.9 7.8 0.3 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 EMD59698.1 - 2.4 7.6 6.8 1.9 8.0 0.3 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tho2 PF11262.3 EMD59698.1 - 3.2 6.7 8.5 0.87 8.5 3.1 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Spc24 PF08286.6 EMD59698.1 - 3.4 7.3 18.7 2.4 7.9 2.3 3.5 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF3450 PF11932.3 EMD59698.1 - 3.5 6.8 18.8 1 8.6 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 EMD59698.1 - 4 6.5 19.1 1.9 7.6 4.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EMD59698.1 - 4.7 7.2 20.8 78 3.2 14.6 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.1 EMD59698.1 - 4.8 7.1 14.6 0.81 9.6 1.3 2.9 1 1 2 3 3 3 0 Up-regulated During Septation DUF342 PF03961.8 EMD59698.1 - 5.3 5.3 13.7 1.1 7.5 2.3 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF342) RasGAP_C PF03836.10 EMD59698.1 - 5.5 6.6 12.2 7.5 6.2 1.8 2.5 1 1 1 2 2 2 0 RasGAP C-terminus Mnd1 PF03962.10 EMD59698.1 - 5.6 6.5 17.7 2.1 7.9 3.5 2.9 1 1 1 2 2 2 0 Mnd1 family BRE1 PF08647.6 EMD59698.1 - 6.8 6.7 15.2 4 7.4 2.0 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.10 EMD59698.1 - 7.7 5.6 12.8 18 4.3 8.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit 4HB_MCP_1 PF12729.2 EMD59698.1 - 8 5.7 11.1 2.6 7.3 1.3 2.5 2 2 0 2 2 2 0 Four helix bundle sensory module for signal transduction Cep57_MT_bd PF06657.8 EMD59698.1 - 8.8 6.3 15.1 3.4 7.6 0.2 3.9 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.11 EMD59699.1 - 5e-34 117.5 16.0 5e-34 117.5 11.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Chordopox_G3 PF06129.7 EMD59699.1 - 0.062 13.4 3.2 0.13 12.4 0.5 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Amidase PF01425.16 EMD59700.1 - 2.7e-104 349.4 0.0 3.2e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EMD59701.1 - 5.8e-06 25.2 34.6 9e-06 24.6 16.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MSC PF09402.5 EMD59701.1 - 0.92 8.1 1.2 2.3 6.8 0.8 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ATP-synt_G PF04718.10 EMD59702.1 - 1.9e-27 95.8 1.7 4.2e-27 94.8 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.8 EMD59702.1 - 0.0013 19.0 4.5 0.076 13.4 2.0 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Suf PF05843.9 EMD59702.1 - 0.0038 16.9 2.1 0.43 10.2 0.1 2.0 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) EMP70 PF02990.11 EMD59702.1 - 0.14 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF3359 PF11839.3 EMD59702.1 - 0.73 10.1 13.0 0.23 11.7 7.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Tape_meas_lam_C PF09718.5 EMD59702.1 - 1.1 9.2 9.6 0.64 9.9 2.6 2.8 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ribosomal_60s PF00428.14 EMD59702.1 - 5.8 7.3 9.1 2.6 8.4 4.4 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DEAD PF00270.24 EMD59703.1 - 2.6e-26 92.1 0.0 2.2e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD59703.1 - 1.4e-22 79.3 0.1 3.9e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD59703.1 - 2.1e-05 24.4 4.2 3.8e-05 23.6 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMD59703.1 - 0.00056 18.4 2.7 0.0043 15.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) Glyco_tranf_2_3 PF13641.1 EMD59705.1 - 2e-22 80.1 0.0 3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD59705.1 - 9.7e-10 38.3 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EMD59705.1 - 1.9e-08 34.2 4.1 1.9e-08 34.2 2.9 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMD59705.1 - 8.5e-08 31.6 0.0 1.4e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Amidohydro_2 PF04909.9 EMD59707.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Clr5 PF14420.1 EMD59708.1 - 3.1e-16 58.9 1.4 9.6e-16 57.4 0.5 2.2 2 0 0 2 2 2 1 Clr5 domain DUF3490 PF11995.3 EMD59708.1 - 0.0051 16.3 0.2 0.016 14.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3490) Arg_repressor PF01316.16 EMD59708.1 - 0.032 13.7 0.1 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain adh_short_C2 PF13561.1 EMD59709.1 - 2.8e-26 92.7 0.0 3.3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD59709.1 - 3.5e-25 88.8 0.1 4.7e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD59709.1 - 7e-11 42.1 0.1 1.1e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMD59709.1 - 0.0019 17.1 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein GATA PF00320.22 EMD59710.1 - 3.5e-16 58.2 5.5 7.1e-16 57.2 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EMD59710.1 - 7.8e-12 45.1 0.0 2.2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EMD59710.1 - 3.4e-09 36.4 0.0 8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EMD59710.1 - 7.6e-08 32.6 0.0 2.9e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EMD59710.1 - 8.7e-08 32.1 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMD59710.1 - 1.5e-05 24.8 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain DUF4428 PF14471.1 EMD59710.1 - 0.027 14.2 0.8 0.027 14.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DHQ_synthase PF01761.15 EMD59711.1 - 0.14 11.0 0.0 11 4.8 0.0 2.0 1 1 1 2 2 2 0 3-dehydroquinate synthase Beta-lactamase PF00144.19 EMD59713.1 - 8e-36 123.7 0.2 1.1e-35 123.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EMD59713.1 - 0.00064 19.2 0.0 0.0039 16.6 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase enzyme family Adenylsucc_synt PF00709.16 EMD59713.1 - 0.24 9.9 0.1 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase ThiF PF00899.16 EMD59714.1 - 2.8e-41 140.5 0.0 5.2e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EMD59714.1 - 1.3e-26 92.0 0.1 2.6e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EMD59714.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain TPR_MLP1_2 PF07926.7 EMD59714.1 - 0.0087 15.8 0.5 0.017 14.8 0.4 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein NAD_binding_7 PF13241.1 EMD59714.1 - 0.019 15.1 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMD59714.1 - 0.088 12.9 0.1 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TelA PF05816.6 EMD59714.1 - 0.13 10.9 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) HET PF06985.6 EMD59715.1 - 1.5e-16 60.8 0.0 3.2e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLX9 PF15341.1 EMD59716.1 - 2.2e-29 102.3 11.8 3.4e-29 101.7 8.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 AATF-Che1 PF13339.1 EMD59716.1 - 0.0078 16.3 2.8 0.011 15.8 1.8 1.4 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor DDE_Tnp_4 PF13359.1 EMD59716.1 - 0.042 13.4 2.3 0.079 12.5 1.6 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease CarD_CdnL_TRCF PF02559.11 EMD59716.1 - 2.4 8.2 4.4 0.69 9.9 0.3 2.0 2 1 0 2 2 2 0 CarD-like/TRCF domain MMgT PF10270.4 EMD59717.1 - 0.58 10.6 0.0 0.58 10.6 0.0 2.5 3 1 0 3 3 3 0 Membrane magnesium transporter Zip PF02535.17 EMD59718.1 - 1e-50 172.6 1.1 1.2e-50 172.3 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2404 PF10296.4 EMD59720.1 - 0.00066 19.7 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) HemY_N PF07219.8 EMD59723.1 - 0.055 13.0 0.3 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 HemY protein N-terminus Catalase PF00199.14 EMD59725.1 - 8.8e-162 538.1 0.3 1.5e-161 537.4 0.2 1.4 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMD59725.1 - 2.2e-18 65.8 0.1 4.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EMD59725.1 - 8.2e-11 41.5 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.20 EMD59726.1 - 7.4e-38 130.1 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD59726.1 - 5.9e-23 81.2 0.0 9.4e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 EMD59726.1 - 1.3e-19 70.7 0.1 4.1e-19 69.1 0.1 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 EMD59726.1 - 1.9 9.0 19.4 0.37 11.2 1.1 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger RRP7 PF12923.2 EMD59727.1 - 9e-28 96.9 4.1 9e-28 96.9 2.8 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EMD59727.1 - 0.005 16.4 0.2 0.052 13.1 0.0 2.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF500 PF04366.7 EMD59728.1 - 1.1e-43 147.6 0.0 1.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) PBP1_TM PF14812.1 EMD59728.1 - 1.1 9.6 7.3 0.63 10.3 3.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleopor_Nup85 PF07575.8 EMD59729.1 - 2.1e-28 98.8 4.7 2.9e-26 91.8 3.3 3.0 1 1 0 1 1 1 1 Nup85 Nucleoporin Prothymosin PF03247.9 EMD59729.1 - 0.011 15.9 10.4 0.02 15.0 7.2 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Sigma70_ner PF04546.8 EMD59729.1 - 1.2 8.7 7.5 0.87 9.1 3.9 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EMD59729.1 - 4.3 6.8 12.3 7.7 6.0 8.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EMD59729.1 - 7.6 6.9 11.5 3.8 7.8 6.2 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTB PF00651.26 EMD59731.1 - 3.9e-08 33.2 0.0 9.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.22 EMD59733.1 - 9.4e-13 48.3 0.0 2.1e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EMD59733.1 - 0.0069 16.2 1.6 0.15 12.0 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HemY_N PF07219.8 EMD59733.1 - 0.0082 15.6 0.0 3.1 7.3 0.1 2.4 2 0 0 2 2 2 2 HemY protein N-terminus TPR_12 PF13424.1 EMD59733.1 - 0.028 14.3 0.1 0.89 9.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1376 PF07120.6 EMD59733.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) DUF3836 PF12930.2 EMD59733.1 - 0.11 11.9 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Ribosomal_L18ae PF01775.12 EMD59734.1 - 8e-58 193.7 2.3 1e-57 193.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain ECH PF00378.15 EMD59735.1 - 2.4e-38 131.6 0.0 2.8e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HET PF06985.6 EMD59736.1 - 4.5e-32 111.0 0.1 1.2e-31 109.6 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS2 PF15003.1 EMD59736.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 HHH_5 PF14520.1 EMD59739.1 - 7.4e-08 32.4 0.1 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EMD59739.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain UDPGP PF01704.13 EMD59741.1 - 2.1e-56 191.2 0.0 3.1e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MR_MLE_C PF13378.1 EMD59741.1 - 6.3e-20 71.2 0.0 1.3e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMD59741.1 - 8.1e-10 39.0 0.0 1.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EMD59741.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 EMD59742.1 - 7.3e-29 100.4 0.5 1.2e-28 99.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD59742.1 - 1e-08 34.8 10.5 1.9e-08 34.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EMD59743.1 - 1.5e-19 70.1 0.0 4.1e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lipocalin PF00061.18 EMD59744.1 - 0.022 14.7 0.6 0.036 14.0 0.4 1.3 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family GWT1 PF06423.7 EMD59745.1 - 6.2e-43 146.1 1.3 1.4e-42 144.9 0.9 1.7 1 0 0 1 1 1 1 GWT1 zf-Tim10_DDP PF02953.10 EMD59747.1 - 1.8e-23 81.5 2.3 2.2e-23 81.3 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EMD59747.1 - 0.07 12.7 0.7 0.13 11.9 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF842 PF05811.8 EMD59747.1 - 0.15 11.5 2.3 0.22 10.9 1.6 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) WD40 PF00400.27 EMD59749.1 - 3.1e-99 321.6 66.9 4.2e-13 48.6 1.3 9.8 8 1 1 9 9 9 9 WD domain, G-beta repeat NACHT PF05729.7 EMD59749.1 - 9.1e-28 96.9 0.1 1.8e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD59749.1 - 7.8e-22 77.9 7.7 6.8e-20 71.6 2.4 3.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD59749.1 - 3e-13 48.7 30.5 0.06 11.4 0.1 7.2 2 1 5 7 7 7 7 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EMD59749.1 - 0.0028 17.0 0.0 2.2 7.6 0.0 4.5 2 1 3 5 5 5 1 Cytolethal distending toxin A/C family AAA_19 PF13245.1 EMD59749.1 - 0.015 15.0 0.0 0.091 12.5 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain tRNA_anti-codon PF01336.20 EMD59749.1 - 0.11 12.3 0.0 51 3.8 0.0 3.4 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain AAA_22 PF13401.1 EMD59749.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain FAD-oxidase_C PF02913.14 EMD59750.1 - 1.6e-59 201.2 0.1 2.5e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMD59750.1 - 2.4e-39 134.0 0.0 8.5e-39 132.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain IATP PF04568.7 EMD59751.1 - 0.05 13.6 7.9 0.07 13.1 4.7 1.7 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP U79_P34 PF03064.11 EMD59751.1 - 0.11 12.0 7.7 0.18 11.2 5.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NUP50 PF08911.6 EMD59753.1 - 6.9e-06 26.3 1.4 6.9e-06 26.3 1.0 10.2 11 3 0 11 11 11 1 NUP50 (Nucleoporin 50 kDa) Lactamase_B_3 PF13483.1 EMD59754.1 - 4.6e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CoA_transf_3 PF02515.12 EMD59755.1 - 2.5e-31 108.4 0.0 5.8e-29 100.6 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III HET PF06985.6 EMD59756.1 - 2.3e-17 63.4 0.3 6.9e-17 61.9 0.2 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPRY PF00622.23 EMD59757.1 - 0.00073 19.6 0.0 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.4 EMD59758.1 - 4.2e-27 94.6 0.0 1.8e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMD59758.1 - 1.1e-18 66.6 0.9 2.3e-18 65.6 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EMD59758.1 - 0.00016 21.0 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EMD59758.1 - 0.00016 21.3 0.3 0.00033 20.4 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD59758.1 - 0.00056 19.5 0.3 0.001 18.7 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD59758.1 - 0.0036 17.2 0.7 0.0069 16.3 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD59758.1 - 0.0079 15.8 0.4 0.014 15.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD59758.1 - 0.023 14.5 0.2 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMD59758.1 - 0.079 12.6 0.7 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.13 EMD59759.1 - 0.00031 20.6 0.0 0.094 12.6 0.0 3.4 3 0 0 3 3 3 1 Putative peptidoglycan binding domain Spc7 PF08317.6 EMD59759.1 - 0.031 12.9 0.7 0.067 11.8 0.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EMD59759.1 - 0.24 11.8 3.7 0.17 12.3 0.3 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spt5_N PF11942.3 EMD59759.1 - 0.6 10.7 8.2 0.043 14.4 1.8 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal IncA PF04156.9 EMD59759.1 - 5 6.6 6.3 14 5.1 4.4 1.8 1 1 0 1 1 1 0 IncA protein Glyco_transf_28 PF03033.15 EMD59760.1 - 4.3e-21 75.1 0.0 3.5e-20 72.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMD59760.1 - 2.3e-05 23.1 0.1 4.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMD59760.1 - 0.016 14.8 0.0 0.016 14.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain DUF1929 PF09118.6 EMD59761.1 - 2e-23 82.3 0.0 3.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EMD59761.1 - 1.2e-12 47.3 4.9 0.013 15.2 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMD59761.1 - 1e-10 41.3 3.5 0.00067 19.7 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 EMD59761.1 - 1.1e-06 27.9 0.0 0.00065 18.8 0.0 2.5 1 1 1 2 2 2 2 Glyoxal oxidase N-terminus Kelch_1 PF01344.20 EMD59761.1 - 1.5e-05 24.4 0.0 0.81 9.2 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 EMD59761.1 - 0.00095 18.8 4.6 5.5 6.9 0.0 4.9 4 2 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 EMD59761.1 - 0.0019 18.3 0.4 0.86 9.8 0.0 4.2 5 2 0 5 5 5 1 Galactose oxidase, central domain PapD_C PF02753.12 EMD59761.1 - 0.031 14.1 0.0 28 4.6 0.0 3.4 3 0 0 3 3 3 0 Pili assembly chaperone PapD, C-terminal domain HPP PF04982.8 EMD59762.1 - 2.6e-38 130.5 6.2 3.8e-38 130.0 4.3 1.2 1 0 0 1 1 1 1 HPP family Tmemb_14 PF03647.8 EMD59762.1 - 0.018 15.4 3.7 0.018 15.3 0.8 2.3 2 1 0 2 2 2 0 Transmembrane proteins 14C Polysacc_synt_C PF14667.1 EMD59762.1 - 0.47 10.2 8.8 0.31 10.8 1.6 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 EMD59762.1 - 2.2 8.5 8.1 17 5.7 2.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Amidohydro_3 PF07969.6 EMD59764.1 - 7.1e-44 150.6 0.2 9.1e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD59764.1 - 5.2e-09 35.7 0.0 1.9e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD59764.1 - 7.4e-08 32.4 0.4 0.00042 20.0 0.0 3.2 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMD59764.1 - 1.4e-06 28.6 4.3 0.0083 16.1 1.5 2.9 3 0 0 3 3 3 2 Amidohydrolase zinc_ribbon_5 PF13719.1 EMD59765.1 - 0.0019 17.7 2.6 0.035 13.6 1.8 2.1 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMD59765.1 - 0.0064 16.1 2.7 0.11 12.2 1.9 2.1 1 1 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EMD59765.1 - 0.0071 16.1 0.5 0.0095 15.7 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbons zf-ribbon_3 PF13248.1 EMD59765.1 - 0.14 11.3 3.6 0.27 10.4 2.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain IBR PF01485.16 EMD59765.1 - 0.17 11.7 1.2 0.27 11.1 0.8 1.3 1 0 0 1 1 1 0 IBR domain Rubredoxin PF00301.15 EMD59765.1 - 0.23 11.3 1.8 14 5.6 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin RRN7 PF11781.3 EMD59765.1 - 0.28 10.7 2.4 0.24 10.9 0.3 1.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EMD59765.1 - 0.32 10.9 1.9 8.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EMD59765.1 - 0.34 10.7 2.3 0.66 9.8 1.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.8 EMD59765.1 - 0.56 9.7 0.1 0.56 9.7 0.1 2.4 1 1 1 2 2 2 0 InsA N-terminal domain zf-LSD1 PF06943.7 EMD59765.1 - 0.62 9.7 3.9 4.1 7.0 0.8 2.2 2 0 0 2 2 2 0 LSD1 zinc finger UPF0547 PF10571.4 EMD59765.1 - 2.3 7.9 5.8 6.6 6.5 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADH_N PF08240.7 EMD59766.1 - 3.8e-20 71.6 2.0 5e-20 71.2 0.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD59766.1 - 1.3e-17 63.5 0.3 2.3e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD59766.1 - 0.00015 22.6 0.0 0.00029 21.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EMD59766.1 - 0.0082 16.5 2.2 0.45 10.9 2.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Gcd10p PF04189.8 EMD59766.1 - 0.022 13.9 0.1 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Gcd10p family 3HCDH_N PF02737.13 EMD59766.1 - 0.034 13.8 0.5 0.054 13.1 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EMD59766.1 - 0.037 12.8 1.8 0.047 12.5 1.3 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EMD59766.1 - 0.075 12.4 1.2 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EMD59766.1 - 0.11 10.9 1.7 0.16 10.4 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EMD59766.1 - 0.18 11.3 2.3 0.26 10.8 1.4 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SCP2 PF02036.12 EMD59767.1 - 2e-24 85.8 0.5 2.3e-24 85.6 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMD59767.1 - 2e-10 40.7 0.1 2.5e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EMD59767.1 - 0.052 12.9 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain F-box PF00646.28 EMD59768.1 - 0.016 14.8 0.4 0.05 13.2 0.3 1.9 1 0 0 1 1 1 0 F-box domain MmgE_PrpD PF03972.9 EMD59768.1 - 0.084 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Arrestin_N PF00339.24 EMD59769.1 - 6.9e-13 48.6 0.1 1.1e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EMD59769.1 - 0.044 12.9 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus DUF2370 PF10176.4 EMD59769.1 - 0.35 10.1 2.6 0.71 9.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) V-ATPase_G PF03179.10 EMD59771.1 - 3.7e-33 113.9 16.6 4.1e-33 113.8 11.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EMD59771.1 - 0.019 14.7 9.1 0.019 14.7 6.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EMD59771.1 - 0.068 12.3 19.1 0.25 10.5 13.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DAG_kinase_N PF14513.1 EMD59771.1 - 0.095 12.9 3.3 0.18 12.0 2.3 1.7 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus DDRGK PF09756.4 EMD59771.1 - 0.33 10.3 14.9 0.4 10.0 10.3 1.0 1 0 0 1 1 1 0 DDRGK domain DXP_reductoisom PF02670.11 EMD59771.1 - 0.36 11.3 1.7 0.47 10.9 1.1 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RGS-like PF09128.6 EMD59771.1 - 0.59 9.6 4.5 0.66 9.4 3.1 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF2422 PF10337.4 EMD59771.1 - 0.65 8.7 3.0 0.68 8.6 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RRF PF01765.14 EMD59771.1 - 0.69 9.3 13.0 0.88 9.0 9.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor OmpH PF03938.9 EMD59771.1 - 0.72 9.7 13.9 0.86 9.5 9.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 EMD59771.1 - 0.74 10.0 5.4 1 9.5 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CDC45 PF02724.9 EMD59771.1 - 1.4 6.8 10.0 1.5 6.7 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein HAUS6_N PF14661.1 EMD59771.1 - 1.6 8.0 7.5 1.9 7.7 5.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Vfa1 PF08432.5 EMD59771.1 - 2 8.4 14.2 2.2 8.2 9.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sds3 PF08598.6 EMD59771.1 - 2.6 7.5 12.0 3.2 7.2 8.3 1.1 1 0 0 1 1 1 0 Sds3-like HrpE PF06188.7 EMD59771.1 - 2.9 7.5 8.3 1.5 8.5 2.6 1.8 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3987 PF13148.1 EMD59771.1 - 4.2 5.8 8.8 4.6 5.6 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribosomal_L6e PF01159.14 EMD59771.1 - 6.6 7.0 13.4 4.5 7.5 2.7 2.0 1 1 1 2 2 2 0 Ribosomal protein L6e SAPS PF04499.10 EMD59771.1 - 7.1 5.1 8.7 7.3 5.0 6.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF883 PF05957.8 EMD59771.1 - 8.9 6.7 9.6 73 3.8 6.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.1 EMD59771.1 - 9.6 5.0 11.8 12 4.7 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GRP PF07172.6 EMD59773.1 - 0.00012 22.5 8.3 0.00031 21.1 5.8 1.7 1 0 0 1 1 1 1 Glycine rich protein family DUF1517 PF07466.6 EMD59773.1 - 2.1 7.2 14.3 2.9 6.7 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ADIP PF11559.3 EMD59777.1 - 1.4e-40 138.6 10.5 1.4e-40 138.6 7.3 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Peptidase_M32 PF02074.10 EMD59777.1 - 0.12 10.9 2.5 0.11 11.1 0.3 1.9 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase DUF641 PF04859.7 EMD59777.1 - 0.19 11.5 10.1 0.18 11.5 3.8 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EMD59777.1 - 1.5 8.8 10.1 1.3 9.0 5.1 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FAD_binding_4 PF01565.18 EMD59778.1 - 9.5e-19 67.2 0.5 1.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.15 EMD59779.1 - 1.6e-27 96.5 0.0 4.1e-27 95.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD59779.1 - 3.5e-24 85.9 0.1 6.9e-24 84.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD59779.1 - 6.3e-11 42.2 0.0 2e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMD59779.1 - 7e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EMD59779.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EMD59779.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EMD59779.1 - 0.016 14.6 0.1 0.054 12.9 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Peptidase_S28 PF05577.7 EMD59779.1 - 0.06 11.9 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HsbA PF12296.3 EMD59780.1 - 0.0022 17.8 1.2 0.0071 16.1 0.7 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A HCV_core PF01542.13 EMD59780.1 - 0.041 14.2 0.6 0.19 12.0 0.3 2.2 1 1 1 2 2 2 0 Hepatitis C virus core protein Fungal_trans_2 PF11951.3 EMD59782.1 - 9.7e-06 24.4 0.7 1.2e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_10 PF12846.2 EMD59782.1 - 0.068 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RTA1 PF04479.8 EMD59783.1 - 2.5e-43 148.1 0.5 2.5e-43 148.1 0.3 1.4 2 0 0 2 2 2 1 RTA1 like protein BIV_Env PF05858.7 EMD59783.1 - 0.0062 14.5 0.2 0.0081 14.1 0.1 1.1 1 0 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) Meth_synt_2 PF01717.13 EMD59784.1 - 2.5e-19 69.4 0.0 3.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMD59784.1 - 2.2e-08 33.7 0.0 0.0039 16.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Kelch_3 PF13415.1 EMD59786.1 - 5.5e-27 93.2 11.3 1.1e-05 25.4 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EMD59786.1 - 7.2e-26 89.7 16.4 8.3e-13 47.8 0.1 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EMD59786.1 - 1e-16 60.2 5.9 0.00078 19.5 0.0 6.5 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EMD59786.1 - 2.3e-12 46.2 4.0 0.15 11.5 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EMD59786.1 - 1.5e-11 43.9 0.4 0.34 10.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMD59786.1 - 3.9e-10 39.0 9.1 0.0011 18.6 0.2 6.5 6 1 0 6 6 6 4 Kelch motif p450 PF00067.17 EMD59787.1 - 2.2e-70 237.4 0.0 2.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EMD59789.1 - 2.1e-19 69.5 1.5 4.6e-19 68.4 1.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EMD59790.1 - 4.4e-49 166.8 1.1 4.4e-49 166.8 0.8 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD59790.1 - 1.3e-05 25.1 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD59790.1 - 0.006 16.2 0.0 0.11 12.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD59790.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 HET PF06985.6 EMD59792.1 - 8.8e-21 74.5 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Het-C PF07217.6 EMD59793.1 - 7.8e-264 876.4 0.0 7.8e-264 876.4 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Gly-zipper_Omp PF13488.1 EMD59793.1 - 0.016 14.7 12.5 0.039 13.5 8.7 1.6 1 0 0 1 1 1 0 Glycine zipper CTNNBL PF08216.6 EMD59794.1 - 1.3e-30 105.1 0.1 3.2e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EMD59794.1 - 0.0039 17.4 0.2 0.038 14.2 0.1 2.6 2 0 0 2 2 2 1 HEAT repeats Dus PF01207.12 EMD59795.1 - 2e-36 125.3 0.0 8e-27 93.8 0.0 2.7 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EMD59795.1 - 0.0011 18.6 7.7 0.037 13.7 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SIS_2 PF13580.1 EMD59795.1 - 0.063 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 SIS domain Bap31 PF05529.7 EMD59796.1 - 1.1e-64 217.4 0.1 1.3e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EMD59796.1 - 0.023 14.1 0.9 0.3 10.6 0.0 2.8 3 0 0 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EMD59796.1 - 0.052 13.5 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Amidase PF01425.16 EMD59797.1 - 1.2e-72 245.1 0.0 1.8e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Amidase His_Phos_2 PF00328.17 EMD59798.1 - 2.6e-35 122.3 0.0 3.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2205 PF10224.4 EMD59801.1 - 3.7e-32 109.7 0.8 3.7e-32 109.7 0.6 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Cecropin PF00272.14 EMD59801.1 - 0.03 13.8 0.3 0.03 13.8 0.2 1.6 2 0 0 2 2 2 0 Cecropin family BUD22 PF09073.5 EMD59801.1 - 0.18 10.8 6.2 0.28 10.1 3.9 1.5 1 1 0 1 1 1 0 BUD22 Peptidase_M16 PF00675.15 EMD59802.1 - 2.2e-58 196.2 1.3 5.9e-58 194.8 0.1 2.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMD59802.1 - 6.2e-40 136.8 0.1 3.1e-39 134.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 EMD59803.1 - 1e-49 167.5 0.0 1.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 CybS 14-3-3 PF00244.15 EMD59804.1 - 3.6e-116 386.2 4.9 4.1e-116 386.0 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 EMD59804.1 - 0.039 13.6 0.5 0.15 11.8 0.0 2.0 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain TerB PF05099.8 EMD59804.1 - 0.045 13.4 1.1 0.098 12.3 0.1 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF837 PF05769.6 EMD59804.1 - 0.12 11.8 3.1 2.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF3461 PF11944.3 EMD59804.1 - 0.16 11.8 1.5 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) IATP PF04568.7 EMD59805.1 - 4.3e-21 74.8 0.3 5.2e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NinG PF05766.7 EMD59805.1 - 0.035 13.8 0.2 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF1864 PF08933.6 EMD59805.1 - 0.086 11.3 0.2 0.11 10.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) MIP PF00230.15 EMD59806.1 - 1.1e-48 165.6 15.8 1.1e-48 165.6 10.9 1.6 2 0 0 2 2 2 1 Major intrinsic protein DUF2721 PF11026.3 EMD59807.1 - 0.026 14.1 0.8 0.049 13.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) WD40 PF00400.27 EMD59808.1 - 5.3e-55 181.4 4.9 6e-09 35.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD59808.1 - 0.045 13.5 0.1 2.3 8.0 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CRT10 PF08728.5 EMD59808.1 - 0.22 9.4 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 CRT10 TRAPP PF04051.11 EMD59809.1 - 2.3e-37 127.8 0.0 2.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF1479 PF07350.7 EMD59811.1 - 5.5e-162 538.9 0.0 6.4e-162 538.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EMD59811.1 - 0.018 15.1 0.3 6.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.13 EMD59812.1 - 1.9e-157 524.1 0.0 2.4e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SGT1 PF07093.6 EMD59813.1 - 0.19 10.0 0.1 0.21 9.9 0.1 1.0 1 0 0 1 1 1 0 SGT1 protein Metallothio_11 PF02066.10 EMD59814.1 - 0.23 11.3 0.3 0.23 11.3 0.2 2.4 4 0 0 4 4 4 0 Metallothionein family 11 bZIP_1 PF00170.16 EMD59815.1 - 3.9e-05 23.5 9.7 0.00043 20.1 3.0 2.2 1 1 1 2 2 2 2 bZIP transcription factor DUF972 PF06156.8 EMD59815.1 - 0.0016 18.7 0.1 0.0046 17.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF972) EAP30 PF04157.11 EMD59815.1 - 0.0059 15.7 1.8 0.0099 15.0 1.2 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family TSC22 PF01166.13 EMD59815.1 - 0.032 14.1 1.6 0.21 11.5 0.2 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EMD59815.1 - 0.67 9.8 12.6 2 8.3 3.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper PIRT PF15099.1 EMD59816.1 - 0.067 12.4 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DIOX_N PF14226.1 EMD59817.1 - 2.2e-25 89.4 0.0 1e-23 84.0 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD59817.1 - 2.6e-13 50.0 0.0 4.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Senescence PF06911.7 EMD59820.1 - 1.1e-45 155.5 9.3 1.6e-45 155.0 6.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein VirionAssem_T7 PF11653.3 EMD59820.1 - 0.25 12.1 6.1 1 10.1 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein AAA PF00004.24 EMD59821.1 - 3.3e-44 150.2 0.3 3.9e-14 52.9 0.0 6.5 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EMD59821.1 - 1.3e-37 129.1 0.0 4.4e-36 124.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EMD59821.1 - 6.2e-30 104.5 23.3 3.9e-25 88.7 0.0 6.5 5 1 0 5 5 5 1 AAA domain AAA_19 PF13245.1 EMD59821.1 - 3.1e-20 71.7 0.6 8e-08 31.9 0.0 5.3 5 0 0 5 5 5 4 Part of AAA domain AAA_5 PF07728.9 EMD59821.1 - 2.8e-15 56.2 1.3 0.0014 18.3 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD59821.1 - 8.3e-15 55.0 9.0 0.002 18.2 0.0 8.4 5 3 0 5 5 5 2 AAA domain AAA_17 PF13207.1 EMD59821.1 - 7.1e-13 49.4 7.4 0.13 13.1 0.0 6.1 5 0 0 5 5 4 4 AAA domain Mg_chelatase PF01078.16 EMD59821.1 - 4e-10 39.2 0.5 0.3 10.1 0.0 5.1 5 1 0 5 5 5 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EMD59821.1 - 5.2e-10 39.2 0.0 0.96 8.9 0.0 6.3 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EMD59821.1 - 3.5e-08 33.5 0.2 1.1 9.4 0.0 4.7 4 0 0 4 4 4 2 RNA helicase RuvB_N PF05496.7 EMD59821.1 - 7.2e-08 31.7 7.1 0.11 11.5 0.0 5.5 5 0 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMD59821.1 - 5.3e-07 29.2 0.3 4 6.8 0.0 4.8 4 0 0 4 4 4 3 IstB-like ATP binding protein AAA_30 PF13604.1 EMD59821.1 - 6.3e-06 25.9 29.1 4.8e-05 23.0 0.1 7.4 7 1 0 7 7 5 1 AAA domain AAA_16 PF13191.1 EMD59821.1 - 7.5e-06 26.0 13.5 2.1 8.2 0.0 5.9 5 0 0 5 5 4 4 AAA ATPase domain AAA_24 PF13479.1 EMD59821.1 - 9.3e-06 25.3 7.3 0.48 9.9 0.2 5.0 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EMD59821.1 - 1.6e-05 24.4 2.0 0.42 10.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EMD59821.1 - 2.1e-05 24.8 20.1 0.73 10.1 0.0 6.6 6 1 0 6 6 4 3 AAA domain Torsin PF06309.6 EMD59821.1 - 6.4e-05 22.8 0.0 11 5.9 0.0 4.4 4 0 0 4 4 4 0 Torsin DUF2075 PF09848.4 EMD59821.1 - 9.2e-05 21.5 12.3 0.0007 18.6 0.0 5.9 5 1 0 5 5 5 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EMD59821.1 - 0.00031 20.0 1.0 0.69 9.1 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein ResIII PF04851.10 EMD59821.1 - 0.0039 17.0 0.0 0.0039 17.0 0.0 4.8 6 0 0 6 6 3 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 EMD59821.1 - 0.014 14.8 5.6 0.15 11.4 0.1 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Guanylate_cyc_2 PF09778.4 EMD59821.1 - 0.018 14.2 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Guanylylate cyclase AAA_33 PF13671.1 EMD59821.1 - 0.02 14.7 15.8 3.1 7.6 0.1 5.6 6 0 0 6 6 4 0 AAA domain KaiC PF06745.8 EMD59821.1 - 0.08 12.0 8.2 2 7.4 0.0 5.0 6 0 0 6 6 6 0 KaiC MobB PF03205.9 EMD59821.1 - 0.084 12.5 0.9 16 5.1 0.0 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B BRE PF06113.7 EMD59821.1 - 0.16 11.0 0.0 0.38 9.7 0.0 1.5 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) OmpH PF03938.9 EMD59821.1 - 1.8 8.5 33.9 2.3 8.1 5.0 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) SBDS PF01172.13 EMD59823.1 - 7.1e-18 64.1 0.2 8.4e-18 63.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MbtH PF03621.8 EMD59823.1 - 0.086 12.2 0.1 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 MbtH-like protein RhoGEF PF00621.15 EMD59824.1 - 1.8e-29 102.8 0.1 3.1e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMD59824.1 - 0.00023 21.3 0.0 0.017 15.3 0.0 2.8 2 1 0 2 2 2 1 PH domain PDZ PF00595.19 EMD59825.1 - 2.4e-06 27.6 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EMD59825.1 - 7.2e-06 25.8 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EMD59825.1 - 0.00054 19.9 0.1 0.0032 17.4 0.0 2.4 2 1 0 2 2 2 1 GRASP55/65 PDZ-like domain Ras PF00071.17 EMD59826.1 - 1.6e-48 164.1 0.0 2e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD59826.1 - 4.8e-14 52.8 0.0 9.4e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMD59826.1 - 4.7e-10 38.9 0.0 6.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EMD59826.1 - 0.0008 19.5 0.1 0.005 17.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EMD59826.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMD59826.1 - 0.02 13.6 1.0 0.61 8.7 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EMD59826.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EMD59826.1 - 0.074 13.1 0.2 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMD59826.1 - 0.075 12.9 0.4 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMD59826.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zn_clus PF00172.13 EMD59827.1 - 4.7e-09 35.9 9.5 7.6e-09 35.3 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD59827.1 - 2.6e-08 33.0 0.2 5e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDZ_assoc PF10600.4 EMD59827.1 - 0.15 12.4 1.9 0.49 10.7 1.3 1.9 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors Epimerase PF01370.16 EMD59828.1 - 1.6e-32 112.8 0.0 3.8e-26 91.9 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMD59828.1 - 5.1e-15 55.1 0.1 1.3e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EMD59828.1 - 4.6e-05 22.4 0.0 0.00027 19.9 0.0 2.1 2 1 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMD59828.1 - 5.3e-05 22.2 0.0 0.0085 15.0 0.0 2.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMD59828.1 - 0.00017 20.4 0.0 0.19 10.3 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD59828.1 - 0.0054 16.7 0.0 0.71 9.8 0.0 3.1 3 0 0 3 3 3 1 NADH(P)-binding DAO PF01266.19 EMD59828.1 - 0.03 13.2 0.1 0.094 11.6 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 EMD59828.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD59828.1 - 0.058 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 EMD59828.1 - 0.11 12.0 0.2 0.75 9.4 0.1 2.3 1 1 0 1 1 1 0 KR domain Glyco_hydro_114 PF03537.8 EMD59829.1 - 1.1e-25 89.2 0.1 1.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Herpes_US9 PF06072.6 EMD59829.1 - 0.16 11.8 0.3 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Polysacc_deac_1 PF01522.16 EMD59830.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase Glycos_transf_1 PF00534.15 EMD59831.1 - 9.1e-09 34.9 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EMD59831.1 - 1.2e-06 28.3 0.0 6.8e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 EMD59831.1 - 0.00022 21.4 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-H2C2_2 PF13465.1 EMD59832.1 - 0.00016 21.7 4.7 0.017 15.4 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD59832.1 - 0.001 19.2 11.1 0.1 12.9 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD59832.1 - 0.018 15.3 15.2 0.056 13.8 1.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type ADC PF06314.6 EMD59832.1 - 0.025 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) zf-C2H2_jaz PF12171.3 EMD59832.1 - 0.028 14.5 5.3 0.15 12.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.11 EMD59834.1 - 9.9e-32 110.0 58.8 7e-31 107.2 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59834.1 - 2e-06 26.6 42.5 0.0022 16.6 12.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Ank_2 PF12796.2 EMD59836.1 - 1.1e-86 285.2 12.4 4.7e-18 65.3 0.0 11.6 4 4 9 13 13 13 11 Ankyrin repeats (3 copies) Ank PF00023.25 EMD59836.1 - 5.5e-73 237.3 21.6 5.8e-07 29.0 0.1 19.5 20 1 0 20 20 20 15 Ankyrin repeat Ank_4 PF13637.1 EMD59836.1 - 2.3e-67 222.2 12.7 2.4e-08 34.2 0.0 15.5 10 4 5 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD59836.1 - 6.9e-62 204.0 14.6 1.6e-07 31.3 0.0 15.5 7 5 8 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD59836.1 - 2.3e-52 169.7 10.0 1.4e-05 24.8 0.0 17.7 20 0 0 20 20 20 9 Ankyrin repeat RicinB_lectin_2 PF14200.1 EMD59839.1 - 0.074 13.4 0.0 0.084 13.2 0.0 1.0 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like IL28A PF15177.1 EMD59840.1 - 0.062 12.8 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin-28A zf-CCHC PF00098.18 EMD59840.1 - 0.097 12.6 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EMD59841.1 - 5.8e-13 48.4 0.0 6.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Clr2 PF10383.4 EMD59845.1 - 4.9e-13 49.2 0.0 1.3e-10 41.4 0.0 2.6 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Tropomyosin PF00261.15 EMD59846.1 - 0.00074 18.6 12.5 0.00074 18.6 8.7 2.7 2 1 1 3 3 3 1 Tropomyosin Med9 PF07544.8 EMD59846.1 - 0.0038 16.9 0.5 0.0038 16.9 0.4 3.0 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 EMD59846.1 - 1.5 7.8 7.6 0.69 9.0 2.7 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 EMD59846.1 - 2.4 7.2 24.0 0.13 11.3 7.8 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EMD59846.1 - 6.1 5.6 24.4 5.3 5.8 9.0 2.5 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EMD59846.1 - 9.3 6.3 13.9 0.59 10.2 1.6 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Pil1 PF13805.1 EMD59848.1 - 0.17 11.0 0.5 0.19 10.8 0.4 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 Ank_2 PF12796.2 EMD59849.1 - 2.5e-41 139.9 1.4 4.9e-13 49.2 0.2 5.8 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMD59849.1 - 3.1e-37 124.5 4.9 4e-10 38.9 0.0 9.8 9 3 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 EMD59849.1 - 5.5e-35 119.1 1.6 2.9e-10 40.3 0.1 7.0 1 1 6 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD59849.1 - 1.4e-28 98.2 8.3 4.3e-09 36.3 0.3 5.9 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD59849.1 - 2.2e-27 92.3 8.4 7.4e-08 31.9 0.0 9.1 9 3 0 9 9 9 4 Ankyrin repeat Peptidase_M16 PF00675.15 EMD59849.1 - 0.041 13.6 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DSHCT PF08148.7 EMD59850.1 - 0.037 13.2 0.9 0.058 12.6 0.6 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain DUF4174 PF13778.1 EMD59850.1 - 0.33 11.0 3.1 0.22 11.6 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) MRP-S26 PF14943.1 EMD59850.1 - 3.9 7.0 15.9 0.18 11.3 5.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Chromo PF00385.19 EMD59852.1 - 2.1e-06 27.3 0.2 2.7e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LBR_tudor PF09465.5 EMD59852.1 - 0.04 13.5 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1957 PF09210.6 EMD59853.1 - 0.012 15.6 1.8 0.012 15.6 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Snf7 PF03357.16 EMD59853.1 - 2.9 7.2 8.2 3.2 7.1 5.7 1.1 1 0 0 1 1 1 0 Snf7 Amidase PF01425.16 EMD59855.1 - 1.3e-78 264.8 0.0 1.8e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Amidase MMtag PF10159.4 EMD59856.1 - 1e-31 108.7 5.9 1e-31 108.7 4.1 3.7 2 1 0 2 2 2 1 Kinase phosphorylation protein Tegument_dsDNA PF12818.2 EMD59856.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Med6 PF04934.9 EMD59857.1 - 1.8e-12 46.9 0.0 2.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Pkinase PF00069.20 EMD59858.1 - 1.3e-59 201.4 0.0 1.8e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD59858.1 - 5.3e-33 114.1 0.0 8.1e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD59858.1 - 1e-12 47.6 0.0 3.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMD59858.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD59858.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.1 EMD59859.1 - 2.3e-17 63.7 0.0 2.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD59859.1 - 0.00016 22.1 0.0 0.0002 21.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD59859.1 - 0.0041 16.7 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Abhydrolase_6 PF12697.2 EMD59860.1 - 3.7e-19 69.5 0.0 5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD59860.1 - 0.0064 16.2 0.0 0.0097 15.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Longin PF13774.1 EMD59861.1 - 5e-28 96.4 0.8 8.6e-28 95.7 0.2 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMD59861.1 - 2.2e-15 56.0 0.1 6.3e-15 54.5 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Seadorna_VP6 PF07407.6 EMD59861.1 - 0.11 11.1 0.5 0.17 10.6 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF1664 PF07889.7 EMD59861.1 - 0.16 11.7 1.7 0.18 11.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 EMD59861.1 - 0.17 10.8 0.5 5.5 5.9 0.1 2.2 1 1 1 2 2 2 0 E1-E2 ATPase ASXH PF13919.1 EMD59862.1 - 1.1e-24 86.7 0.4 2.5e-24 85.6 0.3 1.6 1 0 0 1 1 1 1 Asx homology domain DUF4471 PF14740.1 EMD59862.1 - 0.02 14.1 0.4 0.03 13.5 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) Ndc1_Nup PF09531.5 EMD59862.1 - 1.4 7.2 8.2 1.6 7.0 5.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PDE6_gamma PF04868.7 EMD59862.1 - 1.9 8.3 6.9 6.7 6.6 4.7 2.0 1 1 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Macoilin PF09726.4 EMD59862.1 - 2.7 6.1 14.5 3.1 5.9 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Pec_lyase_C PF00544.14 EMD59863.1 - 5.6e-41 140.2 15.8 1.1e-40 139.3 10.9 1.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMD59863.1 - 0.00073 19.3 20.0 0.002 17.8 13.9 1.8 1 1 0 1 1 1 1 Right handed beta helix region Mito_carr PF00153.22 EMD59865.1 - 5.4e-66 218.3 6.7 8.5e-24 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S41 PF03572.13 EMD59866.1 - 5.2e-07 29.2 0.0 1.5e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 DUF1446 PF07287.6 EMD59866.1 - 0.024 13.1 0.0 0.12 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1446) VTC PF09359.5 EMD59868.1 - 2.6e-96 321.9 1.0 4.2e-96 321.2 0.7 1.4 1 0 0 1 1 1 1 VTC domain CENP-I PF07778.6 EMD59868.1 - 3.8e-89 299.2 0.0 8.3e-89 298.0 0.0 1.5 2 0 0 2 2 2 1 Mis6 SPX PF03105.14 EMD59868.1 - 8e-18 65.1 15.8 1.5e-16 61.0 7.3 3.7 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EMD59868.1 - 8.3e-09 35.5 1.5 8.3e-09 35.5 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3317 PF11779.3 EMD59870.1 - 1.4e-22 78.8 3.7 2.5e-22 78.0 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) WzyE PF06899.6 EMD59870.1 - 0.0066 15.1 1.5 0.0072 15.0 1.0 1.0 1 0 0 1 1 1 1 WzyE protein HXXEE PF13787.1 EMD59870.1 - 0.09 13.1 1.6 0.1 12.9 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DUF3099 PF11298.3 EMD59870.1 - 0.42 10.3 2.0 0.53 10.0 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) DUF4131 PF13567.1 EMD59870.1 - 1 8.7 3.5 1.5 8.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RF-1 PF00472.15 EMD59871.1 - 2.1e-27 95.1 1.6 3e-27 94.6 1.1 1.1 1 0 0 1 1 1 1 RF-1 domain DUF3987 PF13148.1 EMD59871.1 - 0.57 8.6 7.5 0.77 8.2 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Paf1 PF03985.8 EMD59871.1 - 0.79 8.3 8.4 1 8.0 5.8 1.1 1 0 0 1 1 1 0 Paf1 DUF2992 PF11208.3 EMD59871.1 - 9.2 6.1 11.9 13 5.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF816 PF05674.7 EMD59872.1 - 0.1 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) FAD_binding_4 PF01565.18 EMD59875.1 - 2.1e-24 85.6 5.6 2.1e-24 85.6 3.9 1.6 2 0 0 2 2 2 1 FAD binding domain Chitin_bind_1 PF00187.14 EMD59875.1 - 0.0042 17.0 24.9 0.0099 15.8 17.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein HD PF01966.17 EMD59877.1 - 9.4e-05 22.4 0.3 0.0006 19.8 0.0 2.3 2 1 0 2 2 2 1 HD domain Pex16 PF08610.5 EMD59878.1 - 4.5e-117 390.7 0.4 5.1e-117 390.6 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) MitMem_reg PF13012.1 EMD59879.1 - 8.6e-39 132.1 0.0 1.9e-38 131.0 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMD59879.1 - 1.1e-26 92.8 0.0 2.2e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.3 EMD59879.1 - 4.3 5.9 9.1 5.9 5.5 6.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SWIM PF04434.12 EMD59880.1 - 0.013 15.0 5.7 0.019 14.4 0.2 2.3 2 0 0 2 2 2 0 SWIM zinc finger TBX PF12598.3 EMD59880.1 - 0.042 14.2 10.1 1.6 9.1 2.0 2.5 2 0 0 2 2 2 0 T-box transcription factor SWIRM PF04433.12 EMD59882.1 - 3.9e-16 58.9 0.0 6.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.10 EMD59883.1 - 7.8e-101 336.8 0.0 9.8e-101 336.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Glyco_hydro_17 PF00332.13 EMD59884.1 - 4.1e-07 29.3 0.8 9.5e-07 28.1 0.1 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EMD59884.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 ParG PF09274.5 EMD59884.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 ParG Proteasome PF00227.21 EMD59885.1 - 2.5e-54 183.4 0.1 3.1e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMD59885.1 - 1.2e-13 50.0 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EMD59885.1 - 0.066 12.8 0.2 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) QCR10 PF09796.4 EMD59886.1 - 1.9e-27 94.6 0.8 2.5e-27 94.3 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Mfp-3 PF04202.8 EMD59886.1 - 0.17 12.0 0.6 0.22 11.7 0.4 1.1 1 0 0 1 1 1 0 Foot protein 3 Ank_2 PF12796.2 EMD59887.1 - 1.9e-25 89.0 2.4 1e-17 64.2 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD59887.1 - 5.9e-24 83.9 2.0 3.7e-09 36.8 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMD59887.1 - 1.8e-22 77.9 10.6 4.8e-07 29.2 0.2 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EMD59887.1 - 1.4e-11 43.4 0.5 0.015 15.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMD59887.1 - 8.6e-09 35.3 4.9 3.8e-05 23.7 1.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF892 PF05974.7 EMD59887.1 - 0.052 13.3 1.3 33 4.2 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF892) DUF1966 PF09260.6 EMD59887.1 - 0.1 12.7 0.1 1.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) CUE PF02845.11 EMD59887.1 - 0.13 11.7 1.0 6.1 6.4 0.0 2.8 3 0 0 3 3 3 0 CUE domain DUF1843 PF08898.5 EMD59887.1 - 0.25 11.4 8.1 2.6 8.1 0.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1843) Clp_N PF02861.15 EMD59887.1 - 9.9 6.1 10.5 37 4.3 0.2 4.6 4 2 1 5 5 5 0 Clp amino terminal domain Ank PF00023.25 EMD59888.1 - 5.1e-14 51.2 1.8 3.2e-05 23.4 0.2 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMD59888.1 - 1.4e-12 47.7 0.2 1.6e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD59888.1 - 6.9e-12 45.5 0.4 2e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD59888.1 - 1.3e-06 28.0 0.1 0.025 14.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMD59888.1 - 4.7e-06 26.6 0.8 2.6e-05 24.3 0.6 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) YajC PF02699.10 EMD59888.1 - 0.21 11.2 0.6 1.6 8.4 0.1 2.0 1 1 1 2 2 2 0 Preprotein translocase subunit DUF937 PF06078.6 EMD59888.1 - 0.33 11.1 4.9 0.36 11.0 3.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Ank_2 PF12796.2 EMD59889.1 - 1.2e-16 60.8 0.0 7.9e-12 45.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD59889.1 - 3.5e-15 54.9 0.8 0.00043 19.9 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMD59889.1 - 9.4e-14 51.4 0.3 4.9e-08 33.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD59889.1 - 3.8e-13 48.3 0.1 0.00098 19.1 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMD59889.1 - 7.1e-12 45.1 0.6 0.00037 20.6 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HEAT_2 PF13646.1 EMD59889.1 - 0.044 14.0 1.5 4.6 7.5 0.3 3.3 4 0 0 4 4 4 0 HEAT repeats Cation_efflux PF01545.16 EMD59890.1 - 1.4e-36 126.0 7.7 1.7e-36 125.8 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3043 PF11241.3 EMD59890.1 - 0.029 13.9 0.2 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) gpUL132 PF11359.3 EMD59891.1 - 0.16 11.3 0.3 0.2 10.9 0.2 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 Zip PF02535.17 EMD59892.1 - 1.6e-49 168.6 0.4 2e-49 168.3 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TPR_11 PF13414.1 EMD59893.1 - 0.0055 16.3 0.8 0.11 12.1 0.0 2.5 2 1 0 2 2 2 1 TPR repeat ATP-synt_Eps PF04627.8 EMD59893.1 - 0.0088 15.5 0.1 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Glyoxalase PF00903.20 EMD59894.1 - 1.4e-22 80.0 0.2 1.7e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMD59894.1 - 4.2e-14 52.4 0.2 5.1e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMD59894.1 - 4.8e-13 49.6 0.1 2.5e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EMD59894.1 - 4.2e-06 26.7 0.3 0.0004 20.3 0.3 2.9 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EMD59894.1 - 2.5e-05 24.2 0.4 0.39 10.6 0.0 3.2 3 1 0 3 3 3 2 Glyoxalase-like domain Zn_clus PF00172.13 EMD59895.1 - 2.5e-05 24.1 8.3 6.4e-05 22.7 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD59895.1 - 0.0036 16.2 1.4 1.4 7.7 0.1 2.5 2 1 0 2 2 2 2 Fungal specific transcription factor domain NIF PF03031.13 EMD59896.1 - 4.7e-19 68.5 0.0 6.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Baculo_helicase PF04735.7 EMD59896.1 - 0.31 8.3 0.1 0.39 8.0 0.0 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase DUF947 PF06102.7 EMD59897.1 - 2.3e-54 183.7 32.3 2.3e-54 183.7 22.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Stig1 PF04885.8 EMD59898.1 - 8.3e-06 26.0 8.3 8.3e-06 26.0 5.8 3.8 3 1 0 3 3 3 1 Stigma-specific protein, Stig1 Peptidase_M28 PF04389.12 EMD59899.1 - 9.3e-18 64.5 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EMD59899.1 - 1.8e-15 56.6 0.0 3.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EMD59899.1 - 2.1e-06 27.3 0.2 4.7e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 PA domain BTB PF00651.26 EMD59900.1 - 6.3e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SOBP PF15279.1 EMD59901.1 - 8.7 6.6 22.1 1.5 9.0 12.8 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein Abp2 PF09441.5 EMD59905.1 - 7.6e-90 299.5 0.0 1.2e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 LSM14 PF12701.2 EMD59907.1 - 2.1e-35 120.4 0.1 4.5e-35 119.3 0.1 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EMD59907.1 - 9e-19 67.9 2.1 9e-19 67.9 1.5 1.9 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EMD59907.1 - 0.0001 22.1 0.1 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1067 PF06362.6 EMD59907.1 - 0.0052 17.3 1.0 0.015 15.8 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1067) HET PF06985.6 EMD59908.1 - 9e-21 74.4 10.5 7.2e-19 68.3 0.6 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMD59908.1 - 2.4e-09 37.0 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EMD59908.1 - 4.1e-05 22.5 0.0 0.00053 18.9 0.0 2.4 2 1 1 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 EMD59908.1 - 0.00015 21.6 0.0 0.0035 17.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD59908.1 - 0.0021 18.0 0.0 0.0061 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMD59908.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EMD59908.1 - 0.0089 16.2 0.0 0.051 13.7 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMD59908.1 - 0.019 15.0 0.0 0.08 13.1 0.0 2.2 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EMD59908.1 - 0.024 14.7 0.0 0.096 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EMD59908.1 - 0.052 12.4 0.1 0.2 10.4 0.0 1.9 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 EMD59908.1 - 0.072 13.9 0.7 2.5 8.9 0.0 3.2 3 2 0 3 3 3 0 AAA domain Mito_carr PF00153.22 EMD59909.1 - 7.5e-50 166.6 4.7 1.7e-15 56.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EMD59909.1 - 0.0011 18.6 0.2 0.0038 17.0 0.1 1.9 2 0 0 2 2 2 1 UcrQ family Transp_cyt_pur PF02133.10 EMD59910.1 - 1.1e-29 103.2 37.2 1.6e-29 102.7 25.4 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 EMD59911.1 - 4.5e-42 144.0 28.3 4.5e-42 144.0 19.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59911.1 - 1.1e-08 34.1 12.0 1.1e-08 34.1 8.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD59911.1 - 0.0011 17.4 0.7 0.0011 17.4 0.5 4.3 3 2 2 5 5 5 2 MFS/sugar transport protein MFS_1_like PF12832.2 EMD59911.1 - 0.058 13.1 2.2 0.12 12.1 0.0 2.7 3 0 0 3 3 3 0 MFS_1 like family DUF4245 PF14030.1 EMD59911.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Anoctamin PF04547.7 EMD59911.1 - 0.49 8.9 3.9 0.073 11.7 0.1 1.5 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF3684 PF12449.3 EMD59912.1 - 0 1319.5 0.0 0 1319.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EMD59912.1 - 8e-05 22.3 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TINF2_N PF14973.1 EMD59912.1 - 0.074 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus SYCE1 PF15233.1 EMD59912.1 - 0.18 11.7 6.4 0.36 10.7 2.3 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 RuvA_N PF01330.16 EMD59912.1 - 0.18 11.5 0.0 0.67 9.7 0.0 2.0 1 0 0 1 1 1 0 RuvA N terminal domain WLM PF08325.5 EMD59912.1 - 0.19 11.6 3.0 0.09 12.6 0.3 1.8 2 0 0 2 2 2 0 WLM domain TRAPPC9-Trs120 PF08626.6 EMD59913.1 - 1.9e-137 459.4 0.0 1.1e-136 457.0 0.0 2.2 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 6PF2K PF01591.13 EMD59914.1 - 1.4e-73 246.6 0.2 6.8e-52 175.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMD59914.1 - 2.4e-25 89.4 0.0 8.4e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMD59914.1 - 0.00013 21.8 0.1 0.089 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMD59914.1 - 0.0017 17.4 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EMD59914.1 - 0.0077 17.0 0.0 0.04 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMD59914.1 - 0.027 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.10 EMD59915.1 - 0.056 13.6 6.6 0.35 11.1 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) RseC_MucC PF04246.7 EMD59915.1 - 0.13 11.8 0.8 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2892 PF11127.3 EMD59915.1 - 5 7.0 7.5 0.47 10.3 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Cauli_VI PF01693.11 EMD59916.1 - 3.4e-30 103.7 6.1 2.5e-15 56.2 0.6 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EMD59916.1 - 4e-24 85.4 0.0 7.5e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 RNase H TcpE PF12648.2 EMD59917.1 - 0.53 10.4 3.4 7 6.8 1.2 2.4 2 0 0 2 2 2 0 TcpE family EcKinase PF02958.15 EMD59918.1 - 3.5e-19 69.0 0.0 1.2e-18 67.3 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EMD59918.1 - 4.2e-09 36.4 0.8 2.6e-08 33.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD59918.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.11 EMD59919.1 - 4.1e-29 101.3 22.4 4.1e-29 101.3 15.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD59919.1 - 5.4e-11 41.7 18.6 9.9e-11 40.8 12.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD59919.1 - 7.8e-09 34.4 2.0 7.8e-09 34.4 1.4 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein Cyclase PF04199.8 EMD59920.1 - 1.7e-13 50.6 0.1 3.5e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Putative cyclase AA_permease_2 PF13520.1 EMD59922.1 - 1.7e-50 171.8 49.2 2.1e-50 171.5 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD59922.1 - 2.5e-27 95.3 43.8 3.2e-27 95.0 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2182 PF09948.4 EMD59923.1 - 0.0096 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Predicted metal-binding integral membrane protein (DUF2182) BcrAD_BadFG PF01869.15 EMD59924.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Acetyltransf_1 PF00583.19 EMD59925.1 - 2.4e-11 43.4 0.1 4.5e-11 42.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD59925.1 - 4.2e-08 33.2 0.0 2.9e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD59925.1 - 8.7e-07 28.8 0.0 5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD59925.1 - 0.00012 22.1 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD59925.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EMD59925.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein dCMP_cyt_deam_1 PF00383.17 EMD59926.1 - 7.4e-07 28.7 0.1 1.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Staph_haemo PF05480.6 EMD59926.1 - 0.039 13.6 0.3 0.081 12.6 0.2 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein MFS_1 PF07690.11 EMD59927.1 - 2.4e-24 85.7 44.9 2.4e-24 85.7 31.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD59927.1 - 5e-17 61.3 28.0 8.1e-17 60.6 19.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD59927.1 - 2.8e-05 22.9 11.1 2.8e-05 22.9 7.7 3.4 2 2 1 4 4 4 2 Sugar (and other) transporter NACHT PF05729.7 EMD59928.1 - 3.2e-08 33.3 0.4 3.2e-08 33.3 0.3 1.7 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 EMD59928.1 - 5.5e-05 23.4 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_22 PF13401.1 EMD59928.1 - 0.0019 18.3 0.4 0.0068 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 EMD59928.1 - 0.005 16.9 0.7 31 5.1 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat NB-ARC PF00931.17 EMD59928.1 - 0.0069 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Ank_4 PF13637.1 EMD59928.1 - 0.046 14.2 0.6 0.4 11.2 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 EMD59928.1 - 0.074 12.8 2.1 8.1 6.4 0.1 3.3 2 1 0 2 2 2 0 Ankyrin repeat ORC5_C PF14630.1 EMD59929.1 - 9.5e-81 271.2 0.0 1.3e-80 270.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EMD59929.1 - 2.5e-10 40.6 0.1 6.9e-10 39.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD59929.1 - 0.022 14.9 0.1 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0061 PF02696.9 EMD59930.1 - 2.4e-118 395.5 0.0 3e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3216 PF11505.3 EMD59930.1 - 0.0094 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3216) DUF1127 PF06568.6 EMD59930.1 - 0.023 14.0 1.0 0.25 10.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) WD40 PF00400.27 EMD59931.1 - 0.0013 18.5 0.7 0.057 13.3 0.0 3.1 2 1 0 2 2 2 1 WD domain, G-beta repeat ACBP PF00887.14 EMD59932.1 - 1.6e-28 98.2 0.0 3.4e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein HdeA PF06411.6 EMD59933.1 - 0.06 13.3 0.2 0.06 13.3 0.2 1.9 2 1 0 2 2 2 0 HdeA/HdeB family Sugar_tr PF00083.19 EMD59935.1 - 1.1e-75 254.9 19.8 1.4e-75 254.6 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD59935.1 - 2.5e-23 82.3 39.1 1.9e-16 59.7 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD59935.1 - 0.002 16.4 2.8 0.0039 15.4 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_Omp PF13488.1 EMD59935.1 - 0.0071 15.9 3.0 0.023 14.3 2.1 1.8 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 EMD59935.1 - 0.011 15.1 2.5 0.034 13.6 1.7 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1228 PF06779.9 EMD59935.1 - 0.082 12.9 7.0 1.5 8.9 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 EMD59935.1 - 0.18 11.5 6.1 0.64 9.7 4.3 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMD59935.1 - 0.19 11.3 1.2 0.38 10.4 0.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Polyketide_cyc2 PF10604.4 EMD59936.1 - 0.0022 18.1 0.5 0.013 15.6 0.1 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Pyr_redox_2 PF07992.9 EMD59938.1 - 2e-07 31.0 0.0 1e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD59938.1 - 0.00025 20.8 0.0 0.056 13.2 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Malic_M PF03949.10 EMD59938.1 - 0.0066 16.0 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain DAO PF01266.19 EMD59938.1 - 0.041 12.7 0.0 0.36 9.6 0.1 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD59938.1 - 0.057 13.4 0.1 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.22 EMD59939.1 - 4.9e-13 49.1 0.1 7.3e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD59939.1 - 0.0024 17.4 0.2 0.004 16.7 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.13 EMD59940.1 - 5.7e-10 38.9 9.1 5.7e-10 38.9 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD59940.1 - 3e-07 29.5 0.1 6.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD59942.1 - 3.9e-08 32.4 41.5 7.5e-08 31.4 17.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_M28 PF04389.12 EMD59945.1 - 5.3e-30 104.4 0.0 1e-29 103.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD59945.1 - 0.00024 20.6 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_6 PF12697.2 EMD59948.1 - 7.6e-16 58.6 4.7 1.6e-15 57.5 3.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMD59948.1 - 0.013 14.0 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family SBP_bac_6 PF13343.1 EMD59949.1 - 1.7e-12 47.1 1.2 3.3e-12 46.2 0.8 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EMD59949.1 - 1.2e-07 31.5 0.2 1.8e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EMD59949.1 - 0.00083 19.1 9.4 0.0028 17.4 6.3 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Cuticle_3 PF11018.3 EMD59952.1 - 0.014 15.5 2.7 0.042 13.9 1.9 1.7 1 1 0 1 1 1 0 Pupal cuticle protein C1 DUF3172 PF11371.3 EMD59952.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) HET PF06985.6 EMD59953.1 - 0.00025 21.2 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.23 EMD59954.1 - 4.3e-82 276.5 0.4 2.5e-74 250.9 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD59954.1 - 1.6e-11 44.1 0.1 3.9e-11 42.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD59954.1 - 0.0022 17.2 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD59954.1 - 0.01 15.6 0.2 0.029 14.1 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-nanos PF05741.8 EMD59955.1 - 0.049 13.6 0.7 0.079 12.9 0.5 1.3 1 0 0 1 1 1 0 Nanos RNA binding domain FAD_binding_4 PF01565.18 EMD59956.1 - 3.6e-18 65.3 0.1 5.7e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Molydop_binding PF01568.16 EMD59956.1 - 0.041 13.7 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RbsD_FucU PF05025.8 EMD59956.1 - 0.081 13.2 0.2 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 RbsD / FucU transport protein family Lge1 PF11488.3 EMD59957.1 - 0.0054 16.8 0.0 0.0064 16.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 Mst1_SARAH PF11629.3 EMD59957.1 - 0.014 15.1 0.4 0.025 14.3 0.3 1.4 1 1 0 1 1 1 0 C terminal SARAH domain of Mst1 HTH_23 PF13384.1 EMD59960.1 - 7.3e-06 25.4 0.0 8.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EMD59960.1 - 2.1e-05 24.4 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 EMD59960.1 - 0.00024 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EMD59960.1 - 0.00049 20.2 0.1 0.00052 20.1 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix AATase PF07247.7 EMD59962.1 - 6.9e-25 87.5 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMD59962.1 - 5.4e-06 25.4 0.2 0.0002 20.3 0.1 2.2 2 0 0 2 2 2 1 Condensation domain His_binding PF02098.11 EMD59962.1 - 0.0087 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Tick histamine binding protein DUF1702 PF08012.6 EMD59962.1 - 0.016 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) WES_acyltransf PF03007.11 EMD59962.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain SAP30_Sin3_bdg PF13867.1 EMD59964.1 - 0.22 11.4 1.4 0.69 9.8 1.0 1.9 1 1 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 RVT_1 PF00078.22 EMD59965.1 - 9.3e-06 25.1 2.2 1e-05 25.0 1.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1e PF01406.14 EMD59965.1 - 0.12 11.5 0.3 0.12 11.4 0.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CHIPS PF11434.3 EMD59965.1 - 0.22 11.1 1.4 0.24 11.0 0.9 1.0 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Epimerase PF01370.16 EMD59967.1 - 1.7e-16 60.4 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD59967.1 - 5.4e-12 44.9 0.0 7.7e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD59967.1 - 5.3e-11 42.8 1.0 1.1e-09 38.6 0.7 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD59967.1 - 2.2e-07 30.0 0.1 4.3e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMD59967.1 - 2.3e-05 23.4 0.1 3.4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMD59967.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMD59967.1 - 0.00067 18.9 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EMD59967.1 - 0.0019 17.8 0.1 0.0054 16.4 0.1 1.8 1 1 0 1 1 1 1 KR domain PhyH PF05721.8 EMD59968.1 - 4.4e-11 43.2 0.0 7.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMD59968.1 - 0.045 14.0 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase AMP-binding PF00501.23 EMD59969.1 - 1.9e-09 36.4 0.0 2.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD59969.1 - 1.3e-06 29.2 0.0 2.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 EMD59970.1 - 3.3e-14 53.3 0.0 3.8e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 EMD59970.1 - 0.062 13.8 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein zf-CCHC PF00098.18 EMD59971.1 - 0.019 14.8 2.8 0.029 14.3 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle SF-assemblin PF06705.6 EMD59971.1 - 0.022 13.8 0.9 0.025 13.7 0.6 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DOR PF14839.1 EMD59971.1 - 1.6 8.4 9.0 3 7.5 6.2 1.4 1 1 0 1 1 1 0 DOR family ABC_membrane PF00664.18 EMD59972.1 - 3.5e-75 252.9 38.7 7.7e-41 140.3 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD59972.1 - 6.3e-62 207.9 0.0 9.3e-30 103.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD59972.1 - 1.8e-12 46.9 2.9 0.00021 20.6 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD59972.1 - 7.6e-12 45.7 0.0 0.068 13.1 0.0 4.6 4 0 0 4 4 4 4 AAA domain ABC_ATPase PF09818.4 EMD59972.1 - 5.3e-09 35.1 1.2 0.0066 15.0 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMD59972.1 - 7.2e-09 35.8 3.7 0.00041 20.4 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD59972.1 - 1.2e-08 34.3 0.2 0.00077 18.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMD59972.1 - 5.4e-07 30.4 0.0 0.049 14.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD59972.1 - 1.4e-06 28.5 1.0 0.19 11.8 0.0 4.0 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD59972.1 - 2.2e-06 26.9 0.0 0.024 13.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EMD59972.1 - 9.1e-06 25.5 1.9 0.046 13.6 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EMD59972.1 - 1.2e-05 24.8 0.1 0.13 11.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EMD59972.1 - 0.00021 21.3 0.0 0.094 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMD59972.1 - 0.00022 20.8 0.5 2.6 7.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EMD59972.1 - 0.0003 20.6 0.0 1.4 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMD59972.1 - 0.00085 19.0 0.1 0.89 9.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMD59972.1 - 0.0012 19.1 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMD59972.1 - 0.0022 17.9 0.0 16 5.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 EMD59972.1 - 0.0073 16.1 0.3 1.1 9.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EMD59972.1 - 0.014 15.1 0.0 7.2 6.3 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EMD59972.1 - 0.017 14.7 0.6 5.7 6.4 0.0 3.5 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EMD59972.1 - 0.036 14.4 0.3 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMD59972.1 - 0.037 13.4 0.0 9.9 5.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EMD59972.1 - 0.061 13.4 0.0 5.4 7.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 EMD59972.1 - 0.11 12.4 0.1 11 6.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EMD59972.1 - 0.12 11.7 6.2 7 5.9 0.1 4.1 5 0 0 5 5 5 0 AAA-like domain G-alpha PF00503.15 EMD59972.1 - 0.16 10.6 0.0 12 4.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DDE_1 PF03184.14 EMD59973.1 - 3.2e-09 36.2 0.1 3.3e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EMD59974.1 - 0.00039 20.2 2.7 0.00053 19.7 1.9 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EMD59974.1 - 0.0058 16.0 1.3 0.0079 15.6 0.9 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Toxin_17 PF08086.6 EMD59974.1 - 0.15 12.1 1.9 0.31 11.1 1.1 1.6 2 0 0 2 2 2 0 Ergtoxin family PhyH PF05721.8 EMD59975.1 - 1.8e-31 109.8 0.0 2.5e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMD59975.1 - 0.0047 17.2 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.7 EMD59975.1 - 0.12 10.8 0.0 2.5 6.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) adh_short PF00106.20 EMD59976.1 - 2.9e-10 40.2 4.1 1.8e-08 34.4 0.8 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD59976.1 - 2.1e-06 27.6 1.0 2.6e-06 27.3 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMD59976.1 - 0.00033 20.7 0.1 0.00057 19.9 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding GMC_oxred_N PF00732.14 EMD59977.1 - 8.9e-58 195.7 0.0 1.3e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD59977.1 - 1.9e-32 112.5 0.1 3.6e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD59977.1 - 1.9e-07 30.3 0.0 0.00029 19.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD59977.1 - 3.5e-05 22.9 0.0 6.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMD59977.1 - 0.0001 22.2 0.0 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD59977.1 - 0.00011 22.1 0.2 0.00035 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD59977.1 - 0.00068 18.5 0.8 0.0037 16.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD59977.1 - 0.00093 17.7 0.1 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMD59977.1 - 0.0023 18.0 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD59977.1 - 0.015 15.6 0.2 0.32 11.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD59977.1 - 0.033 13.9 0.1 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMD59977.1 - 0.068 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Rpr2 PF04032.11 EMD59978.1 - 0.011 15.5 0.6 0.013 15.3 0.4 1.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-MYND PF01753.13 EMD59978.1 - 0.016 15.0 1.8 0.027 14.3 1.3 1.3 1 0 0 1 1 1 0 MYND finger DUF1660 PF07874.6 EMD59978.1 - 0.12 12.6 1.1 0.15 12.3 0.6 1.4 1 1 0 1 1 1 0 Prophage protein (DUF1660) DUF3133 PF11331.3 EMD59978.1 - 0.28 10.8 6.3 1.7 8.2 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) p450 PF00067.17 EMD59979.1 - 3.1e-51 174.3 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1768 PF08719.6 EMD59980.1 - 1e-43 148.7 0.0 1.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF3081 PF11280.3 EMD59981.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) adh_short_C2 PF13561.1 EMD59982.1 - 1.9e-16 60.5 0.0 2.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_deac_1 PF01522.16 EMD59982.1 - 4.4e-14 52.1 0.0 8.9e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase adh_short PF00106.20 EMD59982.1 - 7.8e-13 48.6 0.0 3.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD59982.1 - 0.00014 21.5 0.0 0.0013 18.3 0.0 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD59982.1 - 0.00032 20.7 0.0 0.00079 19.4 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD59982.1 - 0.0019 17.6 0.0 0.0056 16.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD59982.1 - 0.033 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_57 PF03065.10 EMD59982.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 IF-2B PF01008.12 EMD59983.1 - 4e-59 199.9 0.4 9.2e-35 119.9 0.0 2.6 2 1 0 2 2 2 2 Initiation factor 2 subunit family Tox-HNH-EHHH PF15657.1 EMD59983.1 - 0.12 12.5 0.7 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins NIF PF03031.13 EMD59984.1 - 1.7e-51 174.0 0.0 2.5e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF919 PF06034.6 EMD59984.1 - 0.18 11.4 0.2 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) NACHT PF05729.7 EMD59985.1 - 0.0091 15.6 0.6 0.037 13.6 0.1 2.2 2 1 0 2 2 2 1 NACHT domain Alg14 PF08660.6 EMD59986.1 - 1.4e-29 103.2 0.0 1.5e-14 54.3 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like EspB PF05802.6 EMD59986.1 - 0.07 12.0 0.8 0.098 11.5 0.5 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein KOW PF00467.24 EMD59987.1 - 0.00058 19.4 3.7 0.0023 17.5 2.4 2.2 2 0 0 2 2 2 1 KOW motif Ima1_N PF09779.4 EMD59988.1 - 1.4e-35 122.6 4.7 2.4e-35 121.8 3.2 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 EMD59988.1 - 0.014 15.2 4.8 0.97 9.3 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1284 PF06935.6 EMD59988.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) Rubredoxin PF00301.15 EMD59988.1 - 0.14 12.0 1.8 0.6 10.0 1.3 2.2 1 1 0 1 1 1 0 Rubredoxin zf-CHY PF05495.7 EMD59988.1 - 0.49 10.5 4.0 6 7.1 0.7 2.7 3 0 0 3 3 3 0 CHY zinc finger DUF2296 PF10058.4 EMD59988.1 - 3.5 7.4 7.4 9.1 6.1 1.1 2.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) C1_3 PF07649.7 EMD59988.1 - 5.2 7.2 6.4 9.4 6.3 1.6 2.6 2 1 0 2 2 2 0 C1-like domain Ribosom_S12_S23 PF00164.20 EMD59989.1 - 5.3e-41 138.8 0.4 6.1e-41 138.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Cluap1 PF10234.4 EMD59990.1 - 0.00065 18.9 1.5 0.0011 18.2 1.0 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 TATR PF03430.8 EMD59990.1 - 0.12 11.0 3.4 0.14 10.7 2.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator MFS_1 PF07690.11 EMD59991.1 - 6.4e-38 130.3 22.9 6.4e-38 130.3 15.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_A8 PF01252.13 EMD59991.1 - 0.22 11.1 7.1 4.5 6.8 0.3 3.2 3 0 0 3 3 3 0 Signal peptidase (SPase) II Acyl_transf_3 PF01757.17 EMD59991.1 - 0.35 9.6 36.9 0.045 12.5 9.9 2.7 2 1 0 2 2 2 0 Acyltransferase family peroxidase PF00141.18 EMD59993.1 - 2.3e-48 164.6 0.0 3.6e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Dicty_REP PF05086.7 EMD59994.1 - 0.04 11.6 2.0 0.05 11.3 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EMD59994.1 - 2.2 8.0 7.1 4.6 7.0 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glutaredoxin PF00462.19 EMD59995.1 - 3.3e-16 58.9 0.0 6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Synthase_beta PF11421.3 EMD59995.1 - 0.21 12.2 4.7 4.8 7.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase F1 beta subunit DHquinase_I PF01487.10 EMD59996.1 - 1.6e-61 207.8 0.0 2.7e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 EMD59997.1 - 6.5e-23 80.9 0.0 1.8e-22 79.4 0.0 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD59997.1 - 2e-06 27.6 16.6 3.3e-06 26.8 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 EMD59998.1 - 3.9e-40 137.8 10.3 2.1e-37 128.9 7.1 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMD59998.1 - 8.7e-34 115.8 0.5 1.9e-33 114.7 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMD59998.1 - 4.8e-16 58.9 2.3 5.9e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD59998.1 - 2.5e-10 40.7 0.6 4.7e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD59998.1 - 1e-08 34.5 0.5 0.0022 17.0 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EMD59998.1 - 3e-05 23.0 5.7 0.11 11.2 1.5 3.3 3 1 0 3 3 3 3 FAD binding domain FAD_oxidored PF12831.2 EMD59998.1 - 4.7e-05 22.6 0.6 0.0033 16.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD59998.1 - 0.0018 16.7 1.9 2.5 6.4 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 EMD59998.1 - 0.0041 16.0 5.4 0.15 10.9 0.6 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EMD59998.1 - 0.026 13.6 0.9 6.9 5.7 0.1 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EMD59998.1 - 0.04 13.0 0.5 0.11 11.6 0.3 1.7 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EMD59998.1 - 0.087 11.6 2.1 0.45 9.3 1.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Flavi_NS2B PF01002.14 EMD59999.1 - 0.063 12.8 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Mito_carr PF00153.22 EMD60000.1 - 3.2e-47 158.1 3.6 1.2e-17 63.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.10 EMD60000.1 - 0.056 12.9 0.3 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Ribosomal_60s PF00428.14 EMD60001.1 - 1.2e-24 86.4 12.1 1.7e-24 85.9 8.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EMD60002.1 - 7.1e-39 132.9 8.9 5.2e-17 62.2 0.9 6.2 3 3 1 4 4 4 4 Protein of unknown function (DUF2408) FAD_binding_7 PF03441.9 EMD60002.1 - 0.18 10.9 0.3 0.27 10.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase SET PF00856.23 EMD60003.1 - 3.4e-16 59.9 0.3 1.5e-14 54.6 0.2 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EMD60003.1 - 0.012 16.0 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 SAF domain DUF974 PF06159.8 EMD60004.1 - 1.3e-68 231.1 0.0 1.6e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) HTH_Tnp_Tc5 PF03221.11 EMD60005.1 - 1.9e-11 43.6 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD60005.1 - 5.2e-06 25.9 0.2 8.9e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD60005.1 - 0.0041 17.2 1.1 0.0065 16.6 0.4 1.6 1 1 1 2 2 2 1 Winged helix-turn helix Drf_GBD PF06371.8 EMD60005.1 - 0.033 13.5 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF2500 PF10694.4 EMD60005.1 - 0.055 13.4 1.0 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) HTH_28 PF13518.1 EMD60005.1 - 0.057 13.4 0.1 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD60005.1 - 0.073 12.7 0.3 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain DENN PF02141.16 EMD60006.1 - 4.4e-56 189.5 0.1 9e-56 188.5 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMD60006.1 - 1e-20 73.4 0.0 2.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EMD60006.1 - 9.7e-18 64.0 0.8 1.9e-17 63.0 0.5 1.5 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.11 EMD60006.1 - 0.00034 20.6 6.4 0.00076 19.5 4.4 1.6 1 0 0 1 1 1 1 C1 domain PHD PF00628.24 EMD60006.1 - 0.2 11.3 6.1 0.39 10.4 4.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 EMD60006.1 - 0.71 9.9 4.3 1.4 9.0 3.0 1.5 1 0 0 1 1 1 0 C1-like domain C1_1 PF00130.17 EMD60006.1 - 0.96 9.2 8.0 1.7 8.4 5.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF566 PF04484.7 EMD60008.1 - 9.6 5.6 20.0 11 5.3 13.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PgpA PF04608.8 EMD60009.1 - 0.025 14.3 0.1 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A DUF2109 PF09882.4 EMD60009.1 - 0.12 12.3 0.6 0.22 11.5 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) RGS PF00615.14 EMD60010.1 - 5.5e-30 103.8 1.3 1.1e-29 102.9 0.1 2.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EMD60010.1 - 4.9e-22 77.4 0.1 3.5e-15 55.4 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) p450 PF00067.17 EMD60011.1 - 2.9e-39 134.8 0.0 1.4e-37 129.3 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EMD60012.1 - 6.8e-77 258.0 0.0 7.8e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavoprotein PF02441.14 EMD60013.1 - 5.2e-38 129.6 0.0 6.7e-38 129.2 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein CK_II_beta PF01214.13 EMD60014.1 - 0.076 12.5 0.0 0.077 12.4 0.0 1.0 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Peptidase_S41 PF03572.13 EMD60015.1 - 5.7e-07 29.0 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 Pkinase PF00069.20 EMD60016.1 - 2.3e-59 200.6 0.0 3.1e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60016.1 - 1.1e-28 100.0 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60016.1 - 6.2e-10 38.4 0.0 8.6e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD60016.1 - 0.0057 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CRCB PF02537.10 EMD60017.1 - 0.085 12.7 1.2 0.11 12.3 0.8 1.2 1 0 0 1 1 1 0 CrcB-like protein adh_short PF00106.20 EMD60019.1 - 2.6e-28 99.0 0.1 3.3e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD60019.1 - 1.9e-25 90.0 0.0 2.4e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD60019.1 - 1.9e-07 30.9 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD60019.1 - 0.0088 15.4 0.1 0.061 12.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 EMD60019.1 - 0.15 11.8 0.0 0.88 9.3 0.0 2.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0146) Eno-Rase_NADH_b PF12242.3 EMD60019.1 - 0.45 10.3 2.4 0.67 9.7 1.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldedh PF00171.17 EMD60020.1 - 2.7e-154 513.9 0.1 3.1e-154 513.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2414 PF10309.4 EMD60021.1 - 1.3e-07 31.1 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) zf-CCHC_3 PF13917.1 EMD60022.1 - 5.4e-19 67.6 2.6 5.4e-19 67.6 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EMD60022.1 - 0.0056 16.5 0.9 0.0092 15.8 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle SUZ PF12752.2 EMD60023.1 - 4.5e-16 59.1 5.2 4.5e-16 59.1 3.6 3.3 5 0 0 5 5 5 1 SUZ domain R3H PF01424.17 EMD60023.1 - 2.6e-08 33.4 0.0 5.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain BTB PF00651.26 EMD60024.1 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain SKG6 PF08693.5 EMD60026.1 - 5.3e-07 28.8 0.9 1.1e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EMD60026.1 - 0.00047 19.8 0.0 0.00094 18.9 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EMD60026.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4366 PF14283.1 EMD60026.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3377 PF11857.3 EMD60026.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CcmH PF03918.9 EMD60026.1 - 0.21 10.5 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Steroid_dh PF02544.11 EMD60027.1 - 2.7e-20 72.6 4.4 4.4e-20 71.9 0.4 2.5 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EMD60027.1 - 0.00072 18.9 1.6 0.0013 18.0 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NLPC_P60 PF00877.14 EMD60027.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Sugar_tr PF00083.19 EMD60028.1 - 1.3e-141 472.3 28.9 1.5e-141 472.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60028.1 - 1e-23 83.6 52.5 6.1e-19 67.9 19.2 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EMD60028.1 - 0.02 14.8 0.0 0.02 14.8 0.0 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PPR_2 PF13041.1 EMD60030.1 - 1.9e-32 110.9 2.4 3.6e-15 55.6 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EMD60030.1 - 5.5e-16 57.4 0.3 2.7e-06 27.1 0.0 6.3 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 EMD60030.1 - 7.1e-15 53.8 3.8 1.7e-05 24.4 0.0 6.2 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 EMD60030.1 - 2.2e-14 52.6 0.8 9.8e-06 24.9 0.0 5.1 5 0 0 5 5 5 3 PPR repeat cwf18 PF08315.7 EMD60031.1 - 1e-37 129.4 13.7 1e-37 129.4 9.5 2.3 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF1178 PF06676.6 EMD60031.1 - 7.3 6.7 13.0 9.5 6.4 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Thiolase_C PF02803.13 EMD60032.1 - 7.6e-11 41.5 1.4 2.2e-10 40.0 0.2 2.3 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMD60032.1 - 1.6e-05 24.4 0.0 0.00032 20.2 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EMD60032.1 - 2.7e-05 23.7 0.3 5.3e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EMD60032.1 - 0.00017 20.6 0.1 0.00086 18.3 0.0 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain S4 PF01479.20 EMD60032.1 - 0.0013 18.0 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ketoacyl-synt_C PF02801.17 EMD60032.1 - 0.025 14.4 1.8 0.37 10.6 0.4 3.0 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Kelch_5 PF13854.1 EMD60034.1 - 2.3e-11 43.3 1.0 2.3e-11 43.3 0.7 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 EMD60034.1 - 1.1e-06 28.3 19.9 0.23 11.2 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMD60034.1 - 2.8e-05 24.1 13.5 0.0039 17.3 0.4 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain EphA2_TM PF14575.1 EMD60034.1 - 0.017 15.5 0.0 0.06 13.7 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1360 PF07098.6 EMD60035.1 - 0.014 15.0 0.9 0.039 13.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) DUF3611 PF12263.3 EMD60035.1 - 0.054 12.8 0.3 0.09 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Aminotran_4 PF01063.14 EMD60036.1 - 3.5e-20 72.4 0.0 5.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV CFEM PF05730.6 EMD60037.1 - 2.2e-11 43.4 12.4 4.4e-11 42.4 8.6 1.5 1 0 0 1 1 1 1 CFEM domain CRM1_C PF08767.6 EMD60038.1 - 1.3e-131 438.3 3.5 1.3e-131 438.3 2.4 3.4 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EMD60038.1 - 2.4e-39 134.6 6.7 2.8e-39 134.3 1.8 3.4 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EMD60038.1 - 5.3e-13 48.6 0.6 2.8e-12 46.3 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain YbjQ_1 PF01906.12 EMD60038.1 - 0.15 12.4 0.5 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal-binding HD_assoc PF13286.1 EMD60038.1 - 0.3 11.3 2.4 17 5.7 0.1 4.2 5 0 0 5 5 5 0 Phosphohydrolase-associated domain GDPD PF03009.12 EMD60039.1 - 1.8e-06 27.6 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC1 PF03109.11 EMD60040.1 - 1.7e-32 111.9 0.0 2.9e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EMD60040.1 - 0.0084 15.4 0.0 0.02 14.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family HECT PF00632.20 EMD60041.1 - 3.2e-95 318.9 0.0 4.3e-95 318.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMD60041.1 - 4.5e-32 109.5 19.2 7e-11 41.7 2.6 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EMD60041.1 - 8.5e-17 60.7 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1857 PF08982.6 EMD60042.1 - 1.2e-42 145.0 0.0 1.3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) GF_recep_IV PF14843.1 EMD60043.1 - 0.12 11.9 6.7 0.21 11.2 4.6 1.5 1 1 0 1 1 1 0 Growth factor receptor domain IV MSP1_C PF07462.6 EMD60043.1 - 2.3 6.4 9.1 3.2 6.0 6.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MGC-24 PF05283.6 EMD60043.1 - 8 6.2 18.8 13 5.5 13.0 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Period_C PF12114.3 EMD60043.1 - 9.4 5.7 10.2 14 5.2 7.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ribosomal_L31e PF01198.14 EMD60044.1 - 6.9e-38 128.1 1.5 8.8e-38 127.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zinc_ribbon_6 PF14599.1 EMD60045.1 - 1.2e-22 79.4 3.2 1.2e-22 79.4 2.2 3.8 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EMD60045.1 - 4.5e-15 55.5 22.8 4.5e-15 55.5 15.8 4.1 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EMD60045.1 - 8.8e-11 41.4 4.4 8.8e-11 41.4 3.0 4.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD60045.1 - 1.5e-07 30.9 3.3 1.5e-07 30.9 2.3 5.3 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD60045.1 - 3.4e-06 26.9 6.0 3.4e-06 26.9 4.1 5.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD60045.1 - 5.6e-06 25.9 6.1 5.6e-06 25.9 4.2 6.0 2 1 2 4 4 4 1 zinc-RING finger domain zf-P11 PF03854.9 EMD60045.1 - 0.015 14.8 1.7 0.015 14.8 1.2 4.8 3 2 0 3 3 3 0 P-11 zinc finger Nop14 PF04147.7 EMD60045.1 - 3.2 5.5 13.9 5 4.9 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_31 PF13847.1 EMD60046.1 - 4.5e-13 49.0 0.0 8.9e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD60046.1 - 1.6e-12 47.1 0.0 2.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EMD60046.1 - 1.2e-11 45.2 0.1 1.1e-10 42.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD60046.1 - 1.1e-07 31.8 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD60046.1 - 3.2e-07 30.1 0.0 6.7e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD60046.1 - 5.4e-07 29.1 0.1 9.5e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EMD60046.1 - 7.9e-06 26.2 0.0 2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EMD60046.1 - 9.3e-05 21.5 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 EMD60046.1 - 0.00011 22.5 0.0 0.00035 20.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD60046.1 - 0.00029 20.0 0.0 0.00074 18.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMD60046.1 - 0.00058 20.2 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMD60046.1 - 0.0013 17.9 0.1 0.0028 16.8 0.1 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_3 PF01596.12 EMD60046.1 - 0.002 17.2 0.1 0.0036 16.3 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMD60046.1 - 0.0021 18.8 0.0 0.0046 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD60046.1 - 0.0072 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 EMD60046.1 - 0.01 15.2 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 EMD60046.1 - 0.015 14.0 0.1 0.027 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) FtsJ PF01728.14 EMD60046.1 - 0.035 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EMD60046.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EMD60046.1 - 0.054 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Rav1p_C PF12234.3 EMD60047.1 - 3.4e-261 867.9 0.0 4.5e-261 867.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EMD60047.1 - 1.5e-05 24.7 0.0 1.4 8.8 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat NmrA PF05368.8 EMD60048.1 - 2.2e-09 36.9 0.0 2.9e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD60048.1 - 2.2e-08 34.3 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD60048.1 - 0.00021 20.7 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD60048.1 - 0.0038 17.1 0.3 0.016 15.1 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase Methyltransf_2 PF00891.13 EMD60049.1 - 8.6e-06 25.1 0.0 9.2e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase DUF3926 PF13080.1 EMD60049.1 - 0.034 13.6 0.2 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Methyltransf_2 PF00891.13 EMD60050.1 - 9.5e-31 106.8 1.1 3.7e-30 104.8 0.4 2.1 2 1 0 2 2 2 1 O-methyltransferase TrmB PF01978.14 EMD60050.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EMD60050.1 - 0.00021 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 EMD60050.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 EMD60050.1 - 0.0021 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain FeoC PF09012.5 EMD60050.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_24 PF13412.1 EMD60050.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EMD60050.1 - 0.0088 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.1 EMD60050.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.14 EMD60050.1 - 0.042 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.1 EMD60050.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Tctex-1 PF03645.8 EMD60050.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Tctex-1 family CENP-B_N PF04218.8 EMD60050.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_27 PF13463.1 EMD60050.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.17 EMD60050.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 MarR family zf-met2 PF12907.2 EMD60052.1 - 0.021 14.7 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding DUF1643 PF07799.7 EMD60052.1 - 0.029 14.0 0.1 0.033 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Gin PF10764.4 EMD60052.1 - 0.11 12.1 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin p450 PF00067.17 EMD60053.1 - 6.2e-19 67.8 0.0 6.8e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 EMD60054.1 - 3.9e-29 100.8 0.0 5.8e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Acyl_transf_3 PF01757.17 EMD60055.1 - 1.2e-25 90.0 26.0 3.7e-25 88.4 18.0 1.7 1 1 0 1 1 1 1 Acyltransferase family Chitin_synth_2 PF03142.10 EMD60056.1 - 2.2e-14 52.7 3.7 8e-09 34.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EMD60056.1 - 2.2e-14 53.7 0.0 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD60056.1 - 3.3e-11 43.2 2.8 1.6e-10 40.9 1.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMD60056.1 - 2.5e-10 39.9 0.0 5.6e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD60056.1 - 0.04 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 XPG_I PF00867.13 EMD60056.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 XPG I-region Lipoprotein_3 PF00938.12 EMD60056.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein Acyl_transf_3 PF01757.17 EMD60057.1 - 1.3e-07 30.7 0.3 1.3e-07 30.7 0.2 1.0 1 0 0 1 1 1 1 Acyltransferase family Glyco_transf_54 PF04666.8 EMD60058.1 - 1.3e-06 27.4 0.2 0.015 14.0 0.2 2.1 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.12 EMD60058.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Stig1 PF04885.8 EMD60059.1 - 0.017 15.3 0.9 0.022 14.9 0.7 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Sec23_trunk PF04811.10 EMD60060.1 - 2.8e-76 256.0 0.0 4.6e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMD60060.1 - 2.8e-34 116.6 1.4 6.2e-34 115.5 0.1 2.3 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMD60060.1 - 5.1e-31 107.0 0.0 1.1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMD60060.1 - 3.5e-16 58.4 7.6 7.2e-16 57.4 5.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMD60060.1 - 2e-13 49.8 0.0 1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Cupin_2 PF07883.6 EMD60061.1 - 2.3e-06 26.9 0.1 4.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMD60061.1 - 0.0078 15.8 0.5 0.011 15.3 0.1 1.4 2 0 0 2 2 2 1 Cupin RRM_1 PF00076.17 EMD60062.1 - 1.8e-15 56.2 0.1 5e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60062.1 - 7.2e-12 45.1 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD60062.1 - 1.6e-10 40.6 0.2 3.4e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.7 EMD60063.1 - 1.8e-05 24.0 7.6 4.7e-05 22.6 0.5 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) XH PF03469.9 EMD60063.1 - 0.062 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 XH domain Cu_bind_like PF02298.12 EMD60065.1 - 0.012 15.3 0.4 0.025 14.3 0.3 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain 4F5 PF04419.9 EMD60066.1 - 9.8e-13 48.6 9.0 9.8e-13 48.6 6.2 2.1 2 0 0 2 2 2 1 4F5 protein family Glyco_hydro_61 PF03443.9 EMD60067.1 - 6.1e-44 150.4 0.0 1e-43 149.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2 PF00096.21 EMD60069.1 - 1.4e-10 40.8 10.9 0.011 16.0 0.1 4.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD60069.1 - 9.3e-07 28.7 12.9 0.018 15.3 0.2 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMD60069.1 - 0.047 13.8 5.2 0.51 10.4 0.6 3.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding EMP24_GP25L PF01105.19 EMD60070.1 - 9e-51 172.1 0.0 1e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.20 EMD60071.1 - 2.2e-22 79.7 1.0 3.8e-22 78.9 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD60071.1 - 6.8e-10 38.9 0.8 1.9e-08 34.2 0.5 2.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD60071.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Myb_DNA-bind_6 PF13921.1 EMD60072.1 - 0.059 13.4 0.0 0.34 11.0 0.0 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain zf-C4H2 PF10146.4 EMD60072.1 - 7.2 6.5 8.6 4.7 7.1 4.2 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein Pkinase PF00069.20 EMD60073.1 - 2.2e-36 125.3 0.0 3.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60073.1 - 1.1e-14 54.2 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD60073.1 - 0.015 15.0 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CYSTM PF12734.2 EMD60073.1 - 6.6 6.8 6.0 28 4.8 4.2 2.2 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Nucleoporin_C PF03177.9 EMD60075.1 - 1e-116 390.8 7.7 1.4e-116 390.3 5.3 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMD60075.1 - 4.1e-38 131.2 0.0 5.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like FliD_C PF07195.7 EMD60075.1 - 0.051 12.8 0.4 8.7 5.5 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus HABP4_PAI-RBP1 PF04774.10 EMD60076.1 - 0.00021 21.7 6.7 0.00073 20.0 4.7 1.8 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Mitofilin PF09731.4 EMD60076.1 - 0.012 14.3 0.3 0.012 14.3 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CIAPIN1 PF05093.8 EMD60077.1 - 1.1e-35 121.6 3.0 2.1e-35 120.8 2.1 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Helicase_C PF00271.26 EMD60079.1 - 4.2e-19 68.1 0.0 9.1e-15 54.2 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EMD60079.1 - 1.5e-17 63.6 0.0 3.1e-17 62.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMD60079.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain UBX PF00789.15 EMD60080.1 - 4.4e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EMD60080.1 - 7.9e-06 25.5 0.2 2.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_jaz PF12171.3 EMD60080.1 - 0.037 14.1 0.3 0.063 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Herpes_DNAp_acc PF04929.7 EMD60080.1 - 0.048 12.6 0.0 0.048 12.6 0.0 2.1 1 1 1 2 2 1 0 Herpes DNA replication accessory factor zf-C2H2_2 PF12756.2 EMD60080.1 - 0.1 12.7 0.3 0.1 12.7 0.2 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Exonuc_VII_L PF02601.10 EMD60080.1 - 0.12 11.4 11.4 0.18 10.9 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L11_N PF03946.9 EMD60080.1 - 0.54 9.7 3.2 0.68 9.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Hydantoinase_B PF02538.9 EMD60080.1 - 0.58 8.3 3.3 0.8 7.8 2.3 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PLRV_ORF5 PF01690.12 EMD60080.1 - 1 8.4 17.5 1.4 7.9 12.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CAF-1_p150 PF11600.3 EMD60080.1 - 1.4 8.2 43.5 2 7.7 30.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 EMD60080.1 - 1.5 9.1 9.2 2.2 8.6 6.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein FYDLN_acid PF09538.5 EMD60080.1 - 1.7 9.2 24.8 0.063 13.8 5.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) LMBR1 PF04791.11 EMD60080.1 - 3.3 6.1 8.5 3.8 5.9 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Barttin PF15462.1 EMD60080.1 - 4.4 6.9 12.1 1.1 8.8 5.4 1.9 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Motile_Sperm PF00635.21 EMD60081.1 - 2.1e-26 91.6 0.0 3.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DASH_Dad1 PF08649.5 EMD60081.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 Bcr-Abl_Oligo PF09036.5 EMD60081.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Asn_synthase PF00733.16 EMD60082.1 - 5.2e-67 226.0 0.0 7.2e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMD60082.1 - 5.4e-35 119.8 0.0 9.5e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMD60082.1 - 4.5e-28 97.8 0.0 8.5e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMD60082.1 - 9.2e-08 31.5 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EMD60082.1 - 0.0015 17.4 0.0 0.0037 16.1 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EMD60082.1 - 0.002 16.8 0.0 0.032 12.9 0.0 2.5 1 1 2 3 3 3 1 Glutamine amidotransferases class-II PQ-loop PF04193.9 EMD60083.1 - 7.7e-40 134.2 6.0 3.3e-21 74.5 0.1 3.0 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EMD60083.1 - 0.11 12.3 0.9 1.8 8.5 0.0 2.8 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Mid2 PF04478.7 EMD60084.1 - 1.1e-06 28.1 0.0 2.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1191 PF06697.7 EMD60084.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4366 PF14283.1 EMD60084.1 - 0.86 8.9 0.0 0.86 8.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Ydc2-catalyt PF09159.5 EMD60086.1 - 2.7e-72 243.5 1.0 3.2e-72 243.3 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EMD60086.1 - 5.7e-06 26.2 0.0 0.6 9.9 0.0 3.4 3 0 0 3 3 3 3 Poxvirus A22 protein SAP PF02037.22 EMD60086.1 - 0.084 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 SAP domain Aconitase PF00330.15 EMD60087.1 - 1.3e-156 521.7 0.0 5.7e-156 519.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMD60087.1 - 6.9e-40 136.1 0.0 1.3e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain KH_1 PF00013.24 EMD60087.1 - 1.4e-11 43.8 0.1 1.3e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EMD60087.1 - 2.3e-06 27.1 4.8 1.4e-05 24.5 0.2 3.0 3 0 0 3 3 3 1 KH domain ALS_ss_C PF10369.4 EMD60088.1 - 5.3e-17 61.3 0.0 9.5e-16 57.2 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EMD60088.1 - 2.6e-11 42.7 0.1 4.7e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EMD60088.1 - 7.9e-10 38.3 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF2156 PF09924.4 EMD60089.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) SPX PF03105.14 EMD60091.1 - 1.3e-19 71.0 3.0 1.5e-13 51.1 0.1 3.6 2 1 1 3 3 3 2 SPX domain VTC PF09359.5 EMD60091.1 - 2.1e-10 40.0 0.0 5.6e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 VTC domain DAO PF01266.19 EMD60092.1 - 9.3e-51 172.7 0.0 1.5e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD60092.1 - 1.2e-07 30.9 0.1 3.3e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMD60092.1 - 1.6e-06 27.5 0.0 7.2e-05 22.0 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD60092.1 - 0.00042 20.2 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD60092.1 - 0.0042 17.0 0.2 0.027 14.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EMD60092.1 - 0.018 14.7 0.2 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMD60092.1 - 0.054 11.9 0.1 0.086 11.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMD60092.1 - 0.088 13.2 0.3 0.22 11.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD60092.1 - 0.094 11.5 0.1 0.91 8.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HHH_4 PF14490.1 EMD60092.1 - 0.14 11.9 0.0 20 5.0 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Lycopene_cycl PF05834.7 EMD60092.1 - 0.15 10.9 0.1 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Peroxidase_2 PF01328.12 EMD60093.1 - 3.5e-23 81.7 0.1 6.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 BLIP PF07467.6 EMD60095.1 - 0.022 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) PNK3P PF08645.6 EMD60097.1 - 1e-54 184.3 0.0 2e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EMD60097.1 - 9.3e-28 96.9 0.0 6.6e-27 94.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD60097.1 - 0.0026 16.8 0.0 0.074 12.1 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin KTI12 PF08433.5 EMD60097.1 - 0.038 13.2 0.2 4.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 HAD_2 PF13419.1 EMD60097.1 - 0.11 12.6 0.1 6.4 6.9 0.0 2.8 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 EMD60097.1 - 0.16 12.1 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 EMD60098.1 - 2.6e-46 158.0 0.0 3.7e-32 111.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Terpene_synth_C PF03936.11 EMD60099.1 - 4.1e-07 29.5 0.1 6.4e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain NB-ARC PF00931.17 EMD60100.1 - 5.3e-06 25.5 0.0 1.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain COG5 PF10392.4 EMD60100.1 - 0.0013 18.7 2.7 0.0021 17.9 0.4 2.5 2 1 0 2 2 2 1 Golgi transport complex subunit 5 AAA_22 PF13401.1 EMD60100.1 - 0.0032 17.5 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF948 PF06103.6 EMD60100.1 - 0.072 12.9 0.5 7.2 6.5 0.0 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA_17 PF13207.1 EMD60100.1 - 0.12 13.1 2.9 6.8 7.5 0.0 4.1 3 2 0 3 3 3 0 AAA domain DivIC PF04977.10 EMD60100.1 - 0.17 11.3 1.6 2 7.9 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator PilJ PF13675.1 EMD60100.1 - 0.52 10.6 6.0 0.18 12.1 0.4 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4017 PF13209.1 EMD60101.1 - 0.032 14.0 1.6 0.046 13.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) p450 PF00067.17 EMD60102.1 - 1.3e-71 241.4 0.0 1.7e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med18 PF09637.5 EMD60103.1 - 3e-46 157.9 0.0 3.4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EMD60104.1 - 7.7e-36 123.5 0.1 8.7e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Phage_GPA PF05840.8 EMD60104.1 - 0.15 10.7 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DPBB_1 PF03330.13 EMD60105.1 - 2.4e-05 24.2 0.0 7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ank_2 PF12796.2 EMD60106.1 - 6.6e-12 45.6 0.0 3.1e-10 40.2 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD60106.1 - 6.3e-09 35.2 0.1 0.0014 18.6 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMD60106.1 - 8e-08 32.5 0.3 0.013 15.9 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD60106.1 - 1.3e-07 31.0 0.0 0.004 16.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMD60106.1 - 3.4e-06 27.1 0.1 0.00014 21.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tcp11 PF05794.8 EMD60108.1 - 3.9e-86 289.4 0.0 6.3e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 DSPc PF00782.15 EMD60109.1 - 4.4e-29 100.7 0.0 6.1e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD60109.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMD60109.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Yippee-Mis18 PF03226.9 EMD60109.1 - 0.036 14.1 0.5 0.14 12.1 0.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 EMD60109.1 - 0.13 11.9 2.0 12 5.6 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Init_tRNA_PT PF04179.7 EMD60109.1 - 0.18 10.5 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase zinc_ribbon_5 PF13719.1 EMD60109.1 - 0.19 11.3 1.8 12 5.5 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EMD60110.1 - 1.1e-07 31.6 20.7 0.0094 16.2 1.1 5.0 3 1 1 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD60110.1 - 1.1e-05 25.4 17.0 0.016 15.5 0.6 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMD60110.1 - 0.018 15.1 1.2 0.018 15.1 0.8 4.0 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 EMD60110.1 - 0.052 13.3 2.4 5.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_2 PF12756.2 EMD60110.1 - 9.1 6.4 12.0 4.1 7.5 1.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Vfa1 PF08432.5 EMD60111.1 - 1.3e-60 204.5 21.4 1.4e-60 204.4 14.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2347 PF09804.4 EMD60111.1 - 0.03 13.6 2.8 0.037 13.3 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) BTV_NS2 PF04514.7 EMD60111.1 - 0.087 11.6 15.7 0.1 11.4 10.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tim54 PF11711.3 EMD60111.1 - 0.22 10.1 10.8 0.26 9.8 7.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.1 EMD60111.1 - 0.25 10.8 7.8 0.29 10.6 5.4 1.2 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 EMD60111.1 - 0.3 8.7 16.6 0.34 8.5 11.5 1.0 1 0 0 1 1 1 0 Ycf1 SET PF00856.23 EMD60111.1 - 0.34 11.2 2.8 0.39 11.0 1.9 1.3 1 0 0 1 1 1 0 SET domain Spore_coat_CotO PF14153.1 EMD60111.1 - 0.44 9.9 21.8 0.8 9.1 15.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO GAGA_bind PF06217.7 EMD60111.1 - 0.46 10.3 12.1 0.57 10.0 8.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF262 PF03235.9 EMD60111.1 - 0.67 9.8 10.6 0.79 9.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 RR_TM4-6 PF06459.7 EMD60111.1 - 0.74 9.6 18.4 1.2 9.0 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EMD60111.1 - 0.93 9.2 8.9 1.2 8.9 6.2 1.3 1 0 0 1 1 1 0 DDHD domain U79_P34 PF03064.11 EMD60111.1 - 1 8.8 22.6 1.3 8.4 15.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4094 PF13334.1 EMD60111.1 - 1.1 9.6 13.9 2.3 8.6 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Ctr PF04145.10 EMD60111.1 - 1.2 9.1 3.1 1.8 8.6 2.1 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF4554 PF15091.1 EMD60111.1 - 1.3 7.6 7.6 1.5 7.4 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Atg14 PF10186.4 EMD60111.1 - 1.5 7.7 15.8 1.9 7.3 11.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC45 PF02724.9 EMD60111.1 - 2.3 6.1 23.1 2.8 5.8 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EMD60111.1 - 4 6.7 27.5 5.7 6.2 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Afi1 PF07792.7 EMD60111.1 - 4.3 7.3 12.0 6.1 6.8 8.3 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LMBR1 PF04791.11 EMD60111.1 - 5.4 5.4 7.8 6.4 5.2 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MIP-T3 PF10243.4 EMD60111.1 - 5.6 5.3 31.9 6.5 5.0 22.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TatD_DNase PF01026.16 EMD60112.1 - 3.7e-53 180.3 0.0 4.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Oxidored_q6 PF01058.17 EMD60113.1 - 1.5e-22 79.6 0.0 2.3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.8 EMD60114.1 - 6.7e-28 97.1 0.0 7.9e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EMD60114.1 - 0.056 13.1 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family AFG1_ATPase PF03969.11 EMD60115.1 - 9.7e-60 202.2 0.9 1.4e-28 99.7 0.0 5.0 3 2 2 5 5 5 3 AFG1-like ATPase AAA_16 PF13191.1 EMD60115.1 - 1.9e-05 24.7 0.4 0.0055 16.6 0.0 3.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMD60115.1 - 0.00011 21.8 0.0 0.00039 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD60115.1 - 0.00067 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMD60115.1 - 0.036 14.2 0.0 0.13 12.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMD60115.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EMD60115.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 EMD60115.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain OTCace_N PF02729.16 EMD60116.1 - 3.5e-41 140.1 0.1 5.4e-41 139.5 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EMD60116.1 - 1.5e-40 138.6 0.0 2.6e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LEA_2 PF03168.8 EMD60117.1 - 2.7e-05 24.4 3.4 0.95 9.8 0.2 5.1 5 0 0 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.3 EMD60117.1 - 0.00091 19.2 1.7 0.015 15.2 0.0 3.5 5 1 0 5 5 5 1 Protein of unknown function (DUF3712) HLH PF00010.21 EMD60118.1 - 3.9e-13 48.8 0.0 6.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IBR PF01485.16 EMD60119.1 - 1.6e-07 31.0 16.0 5.7e-05 22.9 7.5 2.1 1 1 1 2 2 2 2 IBR domain UPF0547 PF10571.4 EMD60119.1 - 0.28 10.9 0.2 0.28 10.9 0.1 3.0 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-CXXC PF02008.15 EMD60119.1 - 2.6 7.9 13.2 3 7.7 4.5 3.0 3 0 0 3 3 3 0 CXXC zinc finger domain DUF647 PF04884.9 EMD60120.1 - 7e-105 349.7 2.9 9.6e-105 349.2 2.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EMD60122.1 - 1.7e-11 44.2 0.0 5.4e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain SOG2 PF10428.4 EMD60124.1 - 7.2e-72 242.4 7.7 7.2e-72 242.4 5.3 2.4 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EMD60124.1 - 9.5e-17 60.2 10.2 4.7e-07 29.2 0.2 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD60124.1 - 2e-14 53.0 2.2 6.8e-09 35.3 0.2 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMD60124.1 - 7.2e-08 31.4 0.3 1.6 9.0 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EMD60124.1 - 3.1e-06 26.4 0.1 16 6.2 0.0 5.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EMD60124.1 - 0.0097 15.8 0.2 22 5.5 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat DUF1075 PF06388.6 EMD60124.1 - 0.03 13.9 0.0 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) 60KD_IMP PF02096.15 EMD60125.1 - 4e-16 59.2 0.1 4.7e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EMD60126.1 - 5.6e-21 74.7 0.0 9e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMD60126.1 - 2.3e-06 27.8 0.0 8.1e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMD60126.1 - 0.023 14.3 0.0 0.084 12.5 0.0 2.1 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Mur_ligase_M PF08245.7 EMD60128.1 - 1.7e-06 28.2 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EMD60128.1 - 0.0037 17.2 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF2976 PF11190.3 EMD60130.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) FAD_binding_4 PF01565.18 EMD60131.1 - 4.4e-19 68.3 6.1 8.2e-19 67.4 4.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD60131.1 - 5.4e-05 23.0 0.1 0.00012 21.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Dioxygenase_N PF04444.9 EMD60131.1 - 0.079 12.9 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Catechol dioxygenase N terminus NPCC PF08058.6 EMD60131.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore complex component ACOX PF01756.14 EMD60134.1 - 1.5e-33 115.7 0.4 5.4e-33 113.9 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMD60134.1 - 2.2e-27 95.8 0.8 6e-27 94.4 0.6 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMD60134.1 - 2.5e-12 46.1 0.9 6.8e-12 44.7 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMD60134.1 - 5.2e-07 29.8 0.0 0.0025 17.9 0.0 2.7 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain PP2C PF00481.16 EMD60135.1 - 8.2e-82 274.4 0.0 1.4e-81 273.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMD60135.1 - 0.0013 18.1 0.0 0.0047 16.3 0.0 2.0 2 1 0 2 2 2 1 Protein phosphatase 2C FMN_dh PF01070.13 EMD60136.1 - 6e-108 360.8 0.1 6.9e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMD60136.1 - 3.6e-05 22.8 0.6 6.2e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EMD60136.1 - 0.0011 18.3 0.2 0.02 14.1 0.1 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EMD60136.1 - 0.0022 17.0 0.1 0.0031 16.5 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EMD60136.1 - 0.0046 16.0 0.3 1.2 8.1 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EMD60136.1 - 0.018 14.2 0.7 0.028 13.5 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.16 EMD60136.1 - 0.1 11.6 0.1 0.9 8.5 0.1 2.0 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase WD40 PF00400.27 EMD60137.1 - 1.5e-45 151.4 26.5 8.7e-12 44.4 0.5 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EMD60137.1 - 5.1e-08 31.5 7.6 0.067 11.3 0.1 5.1 2 1 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD60137.1 - 0.00037 19.3 0.2 1.9 7.1 0.1 3.2 1 1 2 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 EMD60137.1 - 0.0021 16.3 0.0 0.0046 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Hira PF07569.6 EMD60137.1 - 0.012 14.7 0.5 3.1 6.9 0.0 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split RicinB_lectin_2 PF14200.1 EMD60137.1 - 0.098 13.0 0.7 0.29 11.5 0.0 2.3 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like AIP3 PF03915.8 EMD60138.1 - 3.5e-159 530.2 15.6 5.6e-159 529.5 10.8 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EMD60138.1 - 0.17 11.2 5.7 0.056 12.8 0.2 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF552 PF04472.7 EMD60138.1 - 0.54 10.2 3.0 0.44 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF552) LsmAD PF06741.8 EMD60139.1 - 8.7e-26 89.8 4.0 2.6e-25 88.3 2.8 1.9 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EMD60139.1 - 1.4e-16 60.1 0.0 5.1e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain Sugar_tr PF00083.19 EMD60140.1 - 5.6e-99 331.7 20.0 1.1e-98 330.7 13.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60140.1 - 1.8e-27 96.0 28.9 2.6e-27 95.4 20.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD60140.1 - 1.3e-05 23.6 3.0 1.3e-05 23.6 2.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMD60140.1 - 0.0024 16.0 9.3 0.0089 14.1 1.1 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.14 EMD60140.1 - 0.0045 15.5 11.2 0.021 13.4 1.5 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.2 EMD60140.1 - 0.0055 16.4 1.4 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family DUF805 PF05656.9 EMD60140.1 - 0.015 15.1 1.8 0.015 15.1 1.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF805) DUF2976 PF11190.3 EMD60140.1 - 0.59 9.6 4.6 2.4 7.7 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Abhydrolase_6 PF12697.2 EMD60141.1 - 3.6e-21 76.1 0.0 4.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60141.1 - 1.2e-13 51.1 0.3 6.6e-12 45.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60141.1 - 5.2e-08 32.7 0.1 4.8e-07 29.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMD60141.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 EMD60141.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EMD60141.1 - 0.021 14.3 0.0 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.16 EMD60141.1 - 0.022 13.9 0.7 0.84 8.8 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family CitF PF04223.7 EMD60141.1 - 0.064 11.9 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) BAAT_C PF08840.6 EMD60141.1 - 0.092 12.4 0.1 0.76 9.4 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 EMD60141.1 - 0.095 11.7 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) HET PF06985.6 EMD60142.1 - 1.8e-30 105.9 0.0 2.9e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PPTA PF01239.17 EMD60144.1 - 8.2e-09 34.4 4.1 0.0015 17.8 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.9 EMD60145.1 - 5.5e-56 188.6 0.3 5.5e-56 188.6 0.2 1.4 2 0 0 2 2 2 1 CHD5-like protein NADH_dh_m_C1 PF15088.1 EMD60145.1 - 0.067 12.6 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial MFS_1 PF07690.11 EMD60146.1 - 1.9e-13 49.8 26.7 1.9e-13 49.8 18.5 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF1689 PF07954.6 EMD60148.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) PP2C PF00481.16 EMD60149.1 - 1.5e-39 135.9 0.0 2.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMD60149.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMD60149.1 - 0.012 15.3 0.2 0.34 10.5 0.0 2.8 4 0 0 4 4 4 0 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 EMD60150.1 - 3.2e-85 286.2 0.1 4.7e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Wbp11 PF09429.5 EMD60150.1 - 0.014 15.3 5.2 0.045 13.7 3.6 1.9 1 0 0 1 1 1 0 WW domain binding protein 11 Nop53 PF07767.6 EMD60150.1 - 0.069 12.1 11.7 0.16 10.9 8.1 1.6 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TPR_6 PF13174.1 EMD60150.1 - 0.085 13.3 1.3 0.36 11.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.21 EMD60150.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 NST1 PF13945.1 EMD60150.1 - 0.32 11.0 6.0 0.71 9.9 4.2 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator eIF3_subunit PF08597.5 EMD60150.1 - 1.3 8.5 15.1 2.4 7.6 10.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TSGP1 PF07771.6 EMD60150.1 - 4.9 7.0 9.3 12 5.7 6.4 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 CRAL_TRIO_2 PF13716.1 EMD60151.1 - 2.6e-37 128.0 0.0 4e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EMD60151.1 - 7.1e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EMD60151.1 - 4.6e-06 26.2 0.0 8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Fungal_trans PF04082.13 EMD60152.1 - 2.8e-29 101.8 0.8 6.8e-29 100.5 0.6 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60152.1 - 9.2e-08 31.8 9.0 1.8e-07 30.9 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.13 EMD60152.1 - 0.34 10.4 5.1 0.8 9.2 3.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Chorismate_synt PF01264.16 EMD60153.1 - 1.7e-127 424.6 0.0 2.3e-127 424.2 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 EMD60153.1 - 6.7 6.6 7.8 0.3 10.8 1.0 2.2 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Porin_3 PF01459.17 EMD60154.1 - 7.5e-59 199.2 5.7 8.5e-59 199.0 4.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 EMD60155.1 - 1.6e-19 69.3 0.6 2.5e-19 68.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 EMD60156.1 - 2e-46 158.2 0.1 2.5e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 EMD60156.1 - 0.00028 19.5 0.1 0.00045 18.8 0.1 1.2 1 0 0 1 1 1 1 Pectinesterase Med3 PF11593.3 EMD60156.1 - 0.075 12.2 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PGA2 PF07543.7 EMD60156.1 - 0.87 9.3 5.7 1.7 8.4 4.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 RR_TM4-6 PF06459.7 EMD60156.1 - 6.3 6.6 7.2 12 5.7 5.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EMD60156.1 - 9.2 4.1 5.8 12 3.7 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_16 PF10294.4 EMD60157.1 - 3e-50 170.0 0.0 3.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase DUF43 PF01861.11 EMD60157.1 - 0.00031 19.7 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 EMD60157.1 - 0.062 13.8 0.0 0.13 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ammonium_transp PF00909.16 EMD60158.1 - 8.9e-67 225.2 21.9 1e-66 225.0 15.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Rhodanese PF00581.15 EMD60159.1 - 3.7e-10 40.1 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain UBA PF00627.26 EMD60159.1 - 0.018 14.9 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain RasGEF PF00617.14 EMD60161.1 - 6.5e-57 192.3 0.1 1.4e-56 191.2 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMD60161.1 - 1.5e-17 63.5 0.0 5.9e-17 61.6 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EMD60161.1 - 9.7e-05 21.8 0.1 0.00036 20.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMD60161.1 - 0.0004 19.7 0.1 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMD60161.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain CAP PF00188.21 EMD60161.1 - 0.059 13.8 0.2 0.24 11.9 0.1 2.0 1 0 0 1 1 1 0 Cysteine-rich secretory protein family SapA PF02199.10 EMD60162.1 - 0.12 12.1 1.3 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Saposin A-type domain Sld5 PF05916.6 EMD60163.1 - 1.3e-26 93.0 0.0 1.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 EMD60164.1 - 4.1e-85 286.0 4.3 1.1e-84 284.7 2.9 1.7 1 1 0 1 1 1 1 DIE2/ALG10 family DUF202 PF02656.10 EMD60165.1 - 6.4e-13 48.7 3.9 6.4e-13 48.7 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EMD60165.1 - 0.62 8.5 2.2 0.66 8.4 1.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tctex-1 PF03645.8 EMD60166.1 - 1.1e-30 105.4 0.2 1.3e-30 105.2 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family TcdA_TcdB PF12919.2 EMD60166.1 - 0.0031 16.0 0.1 0.0036 15.8 0.1 1.0 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain bZIP_2 PF07716.10 EMD60167.1 - 3.6e-10 39.5 14.6 8.4e-10 38.3 10.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMD60167.1 - 0.00078 19.3 12.6 0.0022 17.9 8.7 1.7 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EMD60167.1 - 0.048 13.6 0.7 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Spore_III_AF PF09581.5 EMD60167.1 - 0.22 11.3 5.4 0.32 10.8 3.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) XhlA PF10779.4 EMD60167.1 - 0.25 11.2 6.9 0.47 10.3 4.6 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.10 EMD60167.1 - 0.27 10.7 4.9 0.71 9.3 3.3 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 EMD60167.1 - 0.32 11.3 10.8 0.16 12.2 5.6 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor NapB PF03892.9 EMD60167.1 - 0.39 10.3 2.2 0.5 10.0 0.1 2.1 1 1 1 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) IncA PF04156.9 EMD60167.1 - 0.59 9.6 7.0 0.83 9.2 4.8 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EMD60167.1 - 1.2 7.5 6.8 1.6 7.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EMD60167.1 - 1.2 6.8 4.2 1.5 6.6 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EMD60167.1 - 2.4 7.7 9.1 3.6 7.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2514 PF10721.4 EMD60167.1 - 3.7 7.2 13.7 5.3 6.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) LMBR1 PF04791.11 EMD60167.1 - 4.2 5.8 4.6 5.3 5.5 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF972 PF06156.8 EMD60167.1 - 8.4 6.7 8.7 39 4.6 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-N PF05238.8 EMD60168.1 - 1.9e-125 419.0 0.0 2.1e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like SUR7 PF06687.7 EMD60170.1 - 7.3e-45 153.1 21.0 8.6e-45 152.8 14.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family SKG6 PF08693.5 EMD60171.1 - 6.4e-06 25.3 1.4 1.2e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EMD60171.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Epiglycanin_C PF14654.1 EMD60171.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region PPI_Ypi1 PF07491.6 EMD60172.1 - 3.2e-26 90.7 7.8 2e-25 88.1 5.4 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor Nucleoplasmin PF03066.10 EMD60172.1 - 0.089 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EMD60172.1 - 1 7.3 7.2 1.2 7.0 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DASH_Dad2 PF08654.5 EMD60173.1 - 5.1e-35 119.5 0.7 6.5e-35 119.2 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 EMD60173.1 - 0.35 10.9 2.2 0.45 10.5 0.2 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.6 EMD60174.1 - 6.2e-16 57.8 5.7 2e-15 56.1 3.6 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EMD60174.1 - 2.2e-12 46.2 4.2 2.2e-12 46.2 2.9 3.0 2 0 0 2 2 2 1 Shugoshin C terminus HALZ PF02183.13 EMD60174.1 - 0.27 10.9 2.1 0.56 9.9 0.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4131 PF13567.1 EMD60175.1 - 0.86 8.9 4.9 0.28 10.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3682 PF12446.3 EMD60176.1 - 3.6 7.9 7.9 4.2 7.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) zf-H2C2_2 PF13465.1 EMD60177.1 - 9.8e-14 50.8 9.5 3.6e-08 33.3 0.1 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMD60177.1 - 4.8e-12 45.4 12.2 7.9e-06 25.9 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD60177.1 - 6.6e-11 41.7 12.4 3.8e-05 23.7 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD60177.1 - 1.7e-05 24.8 7.0 0.029 14.4 0.1 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD60177.1 - 2.4e-05 24.3 1.3 0.014 15.6 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EMD60177.1 - 0.01 16.0 0.8 0.023 14.9 0.6 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.7 EMD60177.1 - 0.05 13.7 1.6 0.095 12.8 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMD60177.1 - 0.26 11.2 7.8 9.3 6.3 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 EMD60177.1 - 0.7 9.9 3.0 4.9 7.2 2.0 2.1 1 1 1 2 2 2 0 LIM domain BRO1 PF03097.13 EMD60178.1 - 2.7e-119 398.3 5.2 1e-118 396.3 0.0 2.5 2 1 1 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMD60178.1 - 1.6e-80 270.2 9.2 1.6e-80 270.2 6.4 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV HMA PF00403.21 EMD60179.1 - 9.8e-16 57.6 0.5 1.3e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.9 EMD60179.1 - 0.037 13.8 0.1 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF3568 PF12092.3 EMD60179.1 - 0.09 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF4066 PF13278.1 EMD60180.1 - 1.9e-16 59.7 0.0 1.5e-15 56.9 0.0 1.9 1 1 1 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD60180.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DBC1 PF14443.1 EMD60182.1 - 0.027 13.9 0.2 0.078 12.5 0.1 1.8 1 1 1 2 2 2 0 DBC1 Glyoxalase_3 PF13468.1 EMD60183.1 - 4.9e-25 88.4 0.0 8.5e-25 87.6 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase-like domain BT1 PF03092.11 EMD60183.1 - 0.11 11.2 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 BT1 family Fungal_trans PF04082.13 EMD60184.1 - 2.3e-16 59.4 4.7 4.2e-16 58.5 3.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60184.1 - 1e-07 31.7 11.3 1.7e-07 30.9 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIR2 PF02146.12 EMD60185.1 - 3.9e-38 130.9 0.0 8e-38 129.9 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Peptidase_M24 PF00557.19 EMD60186.1 - 5.8e-53 179.5 0.0 8.8e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMD60186.1 - 2.1e-33 114.5 0.0 3.5e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PNP_UDP_1 PF01048.15 EMD60187.1 - 1.7e-10 40.2 1.6 2.4e-09 36.5 1.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Tyrosinase PF00264.15 EMD60188.1 - 4.4e-44 151.2 0.4 5.7e-44 150.9 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD-oxidase_C PF02913.14 EMD60190.1 - 1.3e-47 162.2 0.0 1.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMD60190.1 - 5.6e-31 106.8 0.0 1.3e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Gln-synt_C PF00120.19 EMD60192.1 - 4.7e-58 196.3 0.0 5.6e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EMD60192.1 - 3.3e-21 74.6 0.0 6.6e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Med1 PF10744.4 EMD60193.1 - 7.6e-29 100.6 0.1 1.5e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF3296 PF11726.3 EMD60194.1 - 0.0059 16.1 0.5 0.0079 15.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Hex_IIIa PF02455.11 EMD60194.1 - 0.029 13.0 0.6 0.031 12.9 0.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Trypan_glycop PF00913.14 EMD60194.1 - 0.042 12.7 2.3 0.05 12.5 1.6 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) ZF-HD_dimer PF04770.7 EMD60194.1 - 0.11 12.6 4.6 0.42 10.6 3.0 1.9 1 1 1 2 2 2 0 ZF-HD protein dimerisation region DUF3020 PF11223.3 EMD60194.1 - 5.8 7.4 10.8 0.12 12.8 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) GFA PF04828.9 EMD60195.1 - 1.9e-17 62.9 0.8 4.2e-17 61.8 0.4 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EMD60195.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.4 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Tbf5 PF06331.7 EMD60196.1 - 1.5e-24 85.5 1.3 1.6e-24 85.4 0.9 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF3783 PF12646.2 EMD60196.1 - 0.0035 17.0 0.5 0.0093 15.6 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3783) SPATA24 PF15175.1 EMD60196.1 - 0.0064 16.2 0.8 0.0064 16.2 0.5 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Med4 PF10018.4 EMD60196.1 - 0.0081 15.5 1.8 0.0083 15.5 1.2 1.0 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2659 PF10858.3 EMD60196.1 - 0.0082 15.5 0.4 0.0082 15.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2659) PaaSYMP PF14738.1 EMD60196.1 - 0.026 14.2 1.5 0.026 14.2 1.0 1.0 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 YokU PF14122.1 EMD60196.1 - 0.14 11.8 0.7 0.17 11.6 0.5 1.2 1 0 0 1 1 1 0 YokU-like protein WBP-1 PF11669.3 EMD60197.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 zf-LITAF-like PF10601.4 EMD60197.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF4381 PF14316.1 EMD60197.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pro_CA PF00484.14 EMD60198.1 - 7.8e-07 29.2 0.2 0.0056 16.6 0.1 2.1 1 1 1 2 2 2 2 Carbonic anhydrase MFS_1 PF07690.11 EMD60199.1 - 4.2e-34 117.8 47.9 4.2e-34 117.8 33.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Isochorismatase PF00857.15 EMD60200.1 - 6.6e-30 104.3 0.1 1.6e-22 80.3 0.1 3.0 2 1 0 3 3 3 2 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 EMD60200.1 - 6.3e-23 81.6 0.1 1.4e-22 80.4 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.1 EMD60200.1 - 6.1e-06 26.0 0.2 1.3e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD60200.1 - 1.2e-05 25.6 0.0 4.5e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD60200.1 - 0.0017 18.2 0.1 0.0078 16.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF159 PF02586.9 EMD60201.1 - 7.1e-60 202.0 0.0 1e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 EMD60202.1 - 9.7e-14 51.0 1.6 4.5e-05 23.2 1.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD60202.1 - 3.4e-06 26.5 0.2 0.54 9.9 0.2 3.7 3 1 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 EMD60202.1 - 0.00047 19.7 0.8 2.8 7.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD60202.1 - 0.0039 16.9 12.7 0.056 13.3 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 EMD60202.1 - 0.0044 16.4 0.1 1.4 8.2 0.2 3.2 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_16 PF13432.1 EMD60202.1 - 0.0099 16.5 0.9 0.76 10.5 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD60202.1 - 0.033 14.1 0.5 0.45 10.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD60202.1 - 0.047 13.4 1.8 32 4.6 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD60202.1 - 0.048 14.3 5.1 7.8 7.4 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD60202.1 - 0.051 13.7 0.1 0.72 10.0 0.0 2.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RabGAP-TBC PF00566.13 EMD60203.1 - 8.4e-51 172.4 0.0 8.4e-51 172.4 0.0 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Aa_trans PF01490.13 EMD60206.1 - 1.1e-50 172.3 37.3 1.2e-50 172.1 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein His_Phos_1 PF00300.17 EMD60207.1 - 2.5e-19 69.9 0.0 4.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) G6PD_bact PF10786.4 EMD60207.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DAO PF01266.19 EMD60208.1 - 5.7e-38 130.7 0.1 7.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD60208.1 - 3.2e-06 27.1 0.0 0.011 15.6 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD60208.1 - 3.5e-06 25.9 0.1 0.15 10.6 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EMD60208.1 - 8e-06 25.7 0.4 0.0035 17.1 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD60208.1 - 0.00019 21.5 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD60208.1 - 0.00079 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMD60208.1 - 0.00097 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMD60208.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Saccharop_dh PF03435.13 EMD60208.1 - 0.019 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EMD60208.1 - 0.036 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EMD60208.1 - 0.038 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EMD60208.1 - 0.086 13.2 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD60208.1 - 0.091 11.6 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N PF00107.21 EMD60209.1 - 7.9e-27 93.3 0.1 5e-26 90.7 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD60209.1 - 3.1e-19 70.1 0.0 6.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD60209.1 - 8.5e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMD60209.1 - 0.00022 20.8 0.1 0.00037 20.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EMD60209.1 - 0.049 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Cpn10 PF00166.16 EMD60209.1 - 0.093 12.6 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit DUF664 PF04978.7 EMD60213.1 - 0.019 15.2 0.4 0.041 14.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF664) Uteroglobin PF01099.12 EMD60213.1 - 0.031 14.0 0.3 0.13 12.0 0.2 1.9 1 1 0 1 1 1 0 Uteroglobin family DUF4381 PF14316.1 EMD60213.1 - 0.15 12.1 0.4 0.27 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ATP-grasp_5 PF13549.1 EMD60214.1 - 0.018 14.2 0.5 0.028 13.6 0.3 1.2 1 0 0 1 1 1 0 ATP-grasp domain DUF1501 PF07394.7 EMD60214.1 - 0.061 12.1 0.5 0.064 12.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) F-box PF00646.28 EMD60215.1 - 0.094 12.3 1.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 F-box domain GIY-YIG PF01541.19 EMD60215.1 - 0.2 12.0 3.4 1 9.7 0.0 3.1 3 0 0 3 3 3 0 GIY-YIG catalytic domain Pox_F11 PF04943.7 EMD60215.1 - 0.26 10.0 1.7 0.4 9.4 1.2 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Phage_GP20 PF06810.6 EMD60217.1 - 0.084 12.3 8.6 0.048 13.0 1.1 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 TBPIP PF07106.8 EMD60217.1 - 1.8 8.0 12.1 0.6 9.6 2.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MFS_1 PF07690.11 EMD60218.1 - 1e-15 57.3 54.5 2.2e-07 29.9 12.7 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD60218.1 - 3.2e-08 32.2 12.5 4.9e-08 31.6 8.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_23 PF13489.1 EMD60220.1 - 4.5e-20 71.9 0.0 6.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD60220.1 - 2.1e-14 53.7 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD60220.1 - 2.6e-12 46.5 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD60220.1 - 1e-11 45.1 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD60220.1 - 5.3e-11 43.0 0.0 7.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD60220.1 - 5.2e-07 29.7 0.0 3.2e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD60220.1 - 2.9e-06 27.5 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMD60220.1 - 3.1e-06 26.1 0.0 4.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 EMD60220.1 - 3.9e-05 22.9 0.0 6.9e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMD60220.1 - 0.0046 16.3 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMD60220.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMD60220.1 - 0.04 12.9 0.0 0.093 11.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MRP-L27 PF09809.4 EMD60221.1 - 1.6e-10 40.6 0.1 2e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 EMD60222.1 - 1.5e-200 668.1 71.1 1.5e-200 668.1 49.3 2.1 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro_81 PF03639.8 EMD60223.1 - 1.4e-143 479.4 0.0 1.8e-143 479.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF4453 PF14627.1 EMD60223.1 - 0.091 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Na_Ca_ex PF01699.19 EMD60224.1 - 4e-47 159.3 35.5 4.6e-25 87.8 8.5 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein 7tm_3 PF00003.17 EMD60224.1 - 4.9 6.4 22.5 0.018 14.4 4.8 3.8 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF1889 PF08986.5 EMD60227.1 - 0.014 15.5 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) TRAP_alpha PF03896.11 EMD60227.1 - 0.069 12.1 1.1 0.08 11.9 0.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 EMD60227.1 - 8.8 4.0 7.1 10 3.8 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EMD60227.1 - 9 4.9 8.3 11 4.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 EMD60228.1 - 5.2 6.3 14.0 6.5 6.0 9.7 1.2 1 0 0 1 1 1 0 Vta1 like Med13_N PF11597.3 EMD60229.1 - 0.06 12.0 2.2 0.092 11.4 1.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal BLOC1_2 PF10046.4 EMD60230.1 - 0.018 15.2 1.8 0.026 14.6 1.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGEF PF00617.14 EMD60230.1 - 0.048 13.3 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 RasGEF domain DUF848 PF05852.6 EMD60230.1 - 0.14 12.0 2.1 0.19 11.5 1.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Acyl_transf_1 PF00698.16 EMD60231.1 - 6.4e-68 229.4 0.0 1.2e-67 228.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMD60231.1 - 1.4e-61 208.1 0.1 3.3e-61 206.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMD60231.1 - 4e-56 189.5 0.6 8.8e-56 188.4 0.4 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EMD60231.1 - 4.4e-55 186.9 0.0 6.7e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMD60231.1 - 2.4e-44 151.1 0.7 1.9e-43 148.3 0.3 2.6 2 1 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD60231.1 - 2.2e-33 114.6 0.1 6.6e-33 113.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMD60231.1 - 9.3e-18 64.5 0.0 3.4e-17 62.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMD60231.1 - 1.3e-12 47.4 0.1 4.1e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMD60231.1 - 2.1e-11 43.8 0.0 6.1e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD60231.1 - 4.8e-11 42.4 0.0 1.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD60231.1 - 8.6e-11 42.8 0.0 3.7e-10 40.7 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EMD60231.1 - 1.1e-07 32.4 0.0 3.4e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMD60231.1 - 7.8e-07 29.2 0.2 2.4e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EMD60231.1 - 1.6e-06 28.5 0.0 4.4e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMD60231.1 - 8e-06 25.5 0.2 2.7e-05 23.8 0.1 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EMD60231.1 - 2.2e-05 24.7 0.0 0.00016 21.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD60231.1 - 0.00092 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EMD60231.1 - 0.004 16.1 0.3 0.0086 15.0 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain CoA_trans PF01144.18 EMD60231.1 - 0.045 12.9 0.3 3 6.9 0.0 3.1 3 0 0 3 3 3 0 Coenzyme A transferase Methyltransf_PK PF05891.7 EMD60231.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EMD60231.1 - 0.081 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EMD60231.1 - 0.16 11.4 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF915 PF06028.6 EMD60231.1 - 0.48 9.4 0.0 0.97 8.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 EMD60232.1 - 3.1e-34 118.2 45.8 1.6e-32 112.6 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EMD60233.1 - 1e-22 81.2 0.0 1.1e-20 74.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD60233.1 - 2.2e-09 36.0 0.0 6.7e-09 34.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD60233.1 - 1.8e-08 34.2 0.0 3.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD60233.1 - 1.2e-05 25.2 0.0 0.0032 17.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD60233.1 - 1.4e-05 24.1 0.0 0.00013 21.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD60233.1 - 0.01 15.5 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EMD60233.1 - 0.014 14.2 0.0 0.33 9.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.19 EMD60233.1 - 0.023 13.6 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.17 EMD60234.1 - 2.6e-42 144.9 0.0 3.2e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EMD60235.1 - 5.3e-14 52.9 0.0 9.8e-14 52.1 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMD60235.1 - 1.5e-05 24.9 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD60235.1 - 0.028 14.1 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 EMD60236.1 - 4.9e-74 249.5 0.0 5.8e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 EMD60237.1 - 1.6e-49 168.6 0.0 2e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SKG6 PF08693.5 EMD60239.1 - 0.0015 17.8 0.3 0.0029 16.8 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AMP-binding PF00501.23 EMD60240.1 - 1.8e-98 329.6 0.1 3e-98 328.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EMD60240.1 - 8.1e-87 290.8 0.5 1.8e-86 289.7 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMD60240.1 - 1.2e-66 223.8 8.1 1.9e-64 216.6 2.4 3.5 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.16 EMD60240.1 - 4.7e-62 210.1 2.5 8.3e-62 209.3 1.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMD60240.1 - 5.1e-61 205.4 8.6 1.2e-57 194.4 4.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EMD60240.1 - 1.3e-53 181.4 0.0 3.8e-53 179.9 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EMD60240.1 - 4.4e-44 149.1 0.9 1.2e-43 147.7 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMD60240.1 - 2.1e-22 79.1 0.0 6.1e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 EMD60240.1 - 4.5e-16 58.9 0.0 1.2e-11 44.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EMD60240.1 - 5.6e-09 36.8 0.0 1.7e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EMD60240.1 - 5.7e-05 23.2 1.7 0.012 15.5 0.0 2.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD60240.1 - 5.9e-05 21.9 0.1 0.2 10.3 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMD60240.1 - 0.00011 21.5 0.6 0.082 12.1 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family Thiolase_N PF00108.18 EMD60240.1 - 0.00018 20.6 0.2 0.00035 19.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EMD60240.1 - 0.0004 19.3 0.0 0.74 8.6 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMD60240.1 - 0.057 12.2 0.3 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Beta_elim_lyase PF01212.16 EMD60241.1 - 4.7e-60 203.1 0.0 5.4e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMD60241.1 - 0.024 12.9 0.0 0.037 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMD60241.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy PF03171.15 EMD60242.1 - 1.5e-16 60.4 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD60242.1 - 3e-16 59.9 0.0 5.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 EMD60243.1 - 2.5e-17 62.6 47.1 3.7e-17 62.0 31.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EMD60244.1 - 4.3e-05 23.3 8.4 8.2e-05 22.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EMD60247.1 - 6.5e-18 64.9 0.2 2.7e-10 39.8 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD60247.1 - 0.00019 21.4 0.1 0.00049 20.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD60247.1 - 0.00023 20.1 0.0 0.00048 19.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD60247.1 - 0.00087 19.2 0.1 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD60247.1 - 0.0033 16.3 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMD60247.1 - 0.011 14.7 0.1 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD60247.1 - 0.014 13.8 0.1 0.023 13.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EMD60247.1 - 0.015 14.1 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMD60247.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMD60247.1 - 0.14 11.9 0.3 0.32 10.7 0.1 1.7 2 0 0 2 2 2 0 ThiF family Aldolase_II PF00596.16 EMD60249.1 - 9.1e-30 103.6 0.2 1.3e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lipase_3 PF01764.20 EMD60250.1 - 6.1e-29 100.4 0.0 9.4e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EMD60250.1 - 2.4e-08 33.6 0.2 4.6e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 EMD60250.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EMD60250.1 - 0.023 14.0 0.5 0.1 11.9 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 EMD60250.1 - 0.046 13.4 0.6 0.098 12.3 0.1 1.8 1 1 1 2 2 2 0 Cutinase Abhydrolase_6 PF12697.2 EMD60250.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ArsA_ATPase PF02374.10 EMD60251.1 - 2.3e-117 391.4 0.1 2.7e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EMD60251.1 - 1.6e-18 66.8 0.1 5.1e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMD60251.1 - 3.3e-09 36.8 0.0 3.3e-08 33.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMD60251.1 - 1.6e-06 27.7 0.2 0.00041 19.8 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EMD60251.1 - 4e-06 26.2 0.1 1.2e-05 24.6 0.0 1.8 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EMD60251.1 - 0.0019 17.6 0.1 0.011 15.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD60251.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMD60251.1 - 0.0051 16.2 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein MipZ PF09140.6 EMD60251.1 - 0.0099 14.9 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 EMD60251.1 - 0.01 15.2 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_10 PF12846.2 EMD60251.1 - 0.017 14.5 0.1 0.05 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EMD60251.1 - 0.029 14.6 0.3 0.087 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EMD60251.1 - 0.039 12.8 0.1 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein VirC1 PF07015.6 EMD60251.1 - 0.05 12.6 0.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein NB-ARC PF00931.17 EMD60251.1 - 0.051 12.4 0.0 0.099 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EMD60251.1 - 0.066 12.4 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ParA PF10609.4 EMD60251.1 - 0.14 12.0 0.7 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 ParA/MinD ATPase like Zeta_toxin PF06414.7 EMD60251.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SNF2_N PF00176.18 EMD60252.1 - 9.6e-81 270.8 0.0 1.6e-80 270.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMD60252.1 - 8.6e-40 135.1 1.3 2.9e-39 133.4 0.3 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EMD60252.1 - 5e-33 113.8 2.0 5e-33 113.8 1.4 4.4 4 1 1 5 5 5 1 HAND Helicase_C PF00271.26 EMD60252.1 - 1.1e-14 53.9 0.0 3.4e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD60252.1 - 1.6e-07 31.3 0.1 1.4e-06 28.2 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD60252.1 - 0.0002 20.9 0.0 0.00063 19.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EMD60252.1 - 0.0049 16.8 0.0 4.3 7.4 0.0 3.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD_2 PF06733.10 EMD60252.1 - 0.083 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 HTH_psq PF05225.11 EMD60255.1 - 8.3e-08 31.6 0.2 1e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 EMD60255.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.7 EMD60255.1 - 0.067 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_Tc3_2 PF01498.13 EMD60255.1 - 0.081 13.0 0.2 0.088 12.8 0.1 1.1 1 0 0 1 1 1 0 Transposase UCH_1 PF13423.1 EMD60256.1 - 3.3e-62 210.6 0.6 5.4e-62 209.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EMD60256.1 - 9.9e-24 84.4 0.0 2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EMD60256.1 - 3.1e-09 36.3 0.0 3.2e-08 33.0 0.0 2.5 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EMD60256.1 - 0.032 14.1 0.0 0.24 11.3 0.1 2.5 4 0 0 4 4 4 0 WD domain, G-beta repeat TUDOR PF00567.19 EMD60257.1 - 0.00012 21.8 0.1 0.00041 20.1 0.0 1.8 2 0 0 2 2 2 1 Tudor domain Tudor-knot PF11717.3 EMD60257.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Agenet PF05641.7 EMD60257.1 - 0.039 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Agenet domain DUF3584 PF12128.3 EMD60257.1 - 0.047 11.0 4.8 0.056 10.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EMD60257.1 - 0.14 11.0 2.0 0.26 10.1 1.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EMD60257.1 - 0.25 11.2 8.6 1.9 8.4 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FadA PF09403.5 EMD60257.1 - 0.56 10.2 6.2 0.46 10.5 3.2 1.6 2 0 0 2 2 2 0 Adhesion protein FadA SlyX PF04102.7 EMD60257.1 - 0.59 10.5 4.4 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 SlyX DivIC PF04977.10 EMD60257.1 - 5.4 6.5 7.2 12 5.4 2.8 2.2 1 1 1 2 2 2 0 Septum formation initiator PAP1 PF08601.5 EMD60258.1 - 1.1e-95 321.3 23.9 1.1e-95 321.3 16.5 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EMD60258.1 - 1e-09 38.2 9.2 2.6e-09 36.8 6.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD60258.1 - 0.015 15.1 17.7 0.025 14.4 9.3 3.0 2 1 1 3 3 3 0 Basic region leucine zipper bZIP_Maf PF03131.12 EMD60258.1 - 0.045 14.0 10.4 0.092 13.0 7.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EMD60258.1 - 0.3 10.6 3.5 0.52 9.8 2.4 1.3 1 0 0 1 1 1 0 IncA protein COesterase PF00135.23 EMD60259.1 - 1.8e-64 218.4 0.0 2.4e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD60259.1 - 0.01 15.4 0.0 0.14 11.7 0.0 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold GMC_oxred_N PF00732.14 EMD60260.1 - 2.5e-59 200.8 0.0 3.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD60260.1 - 4e-31 108.2 0.0 8.8e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD60260.1 - 9.9e-08 31.2 0.2 0.00019 20.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD60260.1 - 4.9e-06 26.7 0.1 0.077 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD60260.1 - 6.5e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD60260.1 - 0.00041 19.3 0.1 0.011 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD60260.1 - 0.0027 17.6 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD60260.1 - 0.028 13.3 0.1 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EMD60260.1 - 0.11 11.5 0.1 0.24 10.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EMD60260.1 - 0.11 11.4 0.2 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EMD60260.1 - 0.17 11.8 0.1 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EMD60260.1 - 0.23 11.8 2.7 0.15 12.4 0.4 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FhuF_C PF11575.3 EMD60261.1 - 0.0053 16.3 2.4 2.1 8.0 0.1 3.1 2 0 0 2 2 2 2 FhuF 2Fe-2S C-terminal domain HET PF06985.6 EMD60262.1 - 2.1e-26 92.7 0.1 4.8e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2231 PF09990.4 EMD60263.1 - 1e-07 32.1 0.2 1.5e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) HET PF06985.6 EMD60266.1 - 6.8e-19 68.4 6.0 3.8e-17 62.7 4.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EMD60267.1 - 2.5e-20 73.0 2.8 9.7e-17 61.4 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EMD60269.1 - 1.8e-78 264.1 26.8 2.2e-78 263.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60269.1 - 1.7e-15 56.5 42.7 2.3e-14 52.8 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD60269.1 - 9.8e-07 27.5 3.0 9.8e-07 27.5 2.1 3.2 3 1 1 4 4 4 1 MFS/sugar transport protein DUF3188 PF11384.3 EMD60269.1 - 2.5 7.7 6.8 0.63 9.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) zf-CCHC PF00098.18 EMD60270.1 - 0.0037 17.1 3.2 0.0058 16.5 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle NDUFB10 PF10249.4 EMD60270.1 - 0.068 13.3 0.4 0.084 13.0 0.3 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 zf-CCHC_5 PF14787.1 EMD60270.1 - 0.11 11.9 3.1 0.2 11.1 2.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 EMD60270.1 - 0.67 9.8 6.9 1.2 9.0 4.8 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G HemY_N PF07219.8 EMD60270.1 - 2.9 7.4 5.4 3.4 7.2 3.7 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DOR PF14839.1 EMD60270.1 - 3.9 7.1 11.4 9.9 5.8 7.9 1.6 1 1 0 1 1 1 0 DOR family DUF3328 PF11807.3 EMD60272.1 - 0.013 15.1 1.2 0.017 14.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DIT1_PvcA PF05141.7 EMD60272.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein HET PF06985.6 EMD60274.1 - 1.2e-29 103.2 0.0 2.3e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) G3P_antiterm PF04309.7 EMD60274.1 - 0.22 10.5 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Aldedh PF00171.17 EMD60276.1 - 2.7e-67 227.1 0.8 3.8e-31 107.9 0.2 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family nsp8 PF08717.5 EMD60276.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 nsp8 replicase TonB_2 PF13103.1 EMD60278.1 - 0.033 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 TonB C terminal Amidohydro_3 PF07969.6 EMD60279.1 - 6.4e-44 150.7 0.0 7.7e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EMD60279.1 - 1.9e-09 37.6 6.5 8.4e-07 28.9 0.0 3.1 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMD60279.1 - 3.2e-09 36.4 0.3 1.6e-08 34.2 0.2 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EMD60279.1 - 4.9e-08 33.3 4.9 2.5e-05 24.4 0.1 2.6 3 1 0 3 3 3 2 Amidohydrolase WD40 PF00400.27 EMD60280.1 - 3e-107 347.0 49.8 1.3e-13 50.2 0.1 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat NACHT PF05729.7 EMD60280.1 - 7.5e-27 94.0 0.1 1.4e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD60280.1 - 4.4e-22 78.7 5.9 3.2e-20 72.7 2.1 3.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD60280.1 - 4.5e-16 58.0 24.9 0.046 11.8 0.2 8.2 1 1 7 8 8 8 8 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EMD60280.1 - 6.2e-10 38.6 0.0 0.043 13.1 0.0 4.7 1 1 3 4 4 4 4 Cytolethal distending toxin A/C family Asp_decarbox PF02261.11 EMD60280.1 - 0.0082 15.7 0.0 38 3.8 0.0 5.6 1 1 7 8 8 8 0 Aspartate decarboxylase AAA_22 PF13401.1 EMD60280.1 - 0.015 15.4 0.3 0.073 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD60280.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_18 PF00704.23 EMD60281.1 - 6.2e-25 88.3 1.4 1.1e-23 84.2 0.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EMD60282.1 - 0.00097 18.9 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 3 LysM domain LysM PF01476.15 EMD60283.1 - 3.2e-12 46.1 0.3 6.7e-07 29.0 0.1 3.3 3 0 0 3 3 3 2 LysM domain Cu2_monooxygen PF01082.15 EMD60283.1 - 0.036 14.0 0.1 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain LysM PF01476.15 EMD60284.1 - 7.7e-28 96.1 3.2 1.4e-05 24.8 0.1 4.5 4 0 0 4 4 4 4 LysM domain Glyco_hydro_18 PF00704.23 EMD60286.1 - 2.3e-77 260.7 3.5 3.5e-77 260.1 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD60286.1 - 5.3e-09 35.9 19.0 5.3e-09 35.9 13.1 4.6 4 0 0 4 4 4 2 Chitin recognition protein Peroxidase_2 PF01328.12 EMD60288.1 - 3.9e-16 58.6 0.0 1e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 HET PF06985.6 EMD60290.1 - 4.7e-17 62.4 0.1 6.3e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRI12 PF06609.8 EMD60291.1 - 2.4e-34 118.4 31.6 4.2e-34 117.7 21.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMD60291.1 - 2.5e-18 65.9 53.7 2.5e-18 65.9 37.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD60291.1 - 2e-08 33.2 15.2 2e-08 33.2 10.5 3.3 3 1 0 4 4 4 2 Sugar (and other) transporter Oxidored_molyb PF00174.14 EMD60292.1 - 2e-47 160.7 0.0 4.7e-47 159.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMD60292.1 - 6.6e-24 84.0 3.3 1.1e-23 83.3 2.3 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF1680 PF07944.7 EMD60292.1 - 0.086 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) DAGK_cat PF00781.19 EMD60293.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Albumin_I PF08027.6 EMD60293.1 - 0.13 12.0 2.1 0.18 11.5 1.5 1.3 1 1 0 1 1 1 0 Albumin I PAF-AH_p_II PF03403.8 EMD60294.1 - 2.7e-16 58.8 0.0 5.1e-08 31.6 0.0 2.2 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMD60294.1 - 3e-08 33.5 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD60294.1 - 8.5e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD60294.1 - 1.5e-05 24.0 0.1 3.3e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EMD60294.1 - 0.0044 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EMD60294.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EMD60294.1 - 0.25 10.1 2.1 2.4 6.8 1.4 2.1 1 1 0 1 1 1 0 Chlorophyllase Fungal_trans_2 PF11951.3 EMD60295.1 - 3.7e-14 52.1 12.0 5.8e-14 51.4 8.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.23 EMD60295.1 - 0.067 12.6 0.4 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 adh_short PF00106.20 EMD60296.1 - 1.3e-19 70.6 0.0 2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD60296.1 - 2.8e-08 33.6 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD60296.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMD60296.1 - 0.00079 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EMD60296.1 - 0.0034 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMD60296.1 - 0.0041 16.0 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMD60296.1 - 0.021 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAM178 PF14816.1 EMD60296.1 - 0.038 12.6 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 NAD_binding_10 PF13460.1 EMD60296.1 - 0.082 12.8 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding AA_permease_2 PF13520.1 EMD60297.1 - 1.2e-50 172.3 54.1 1.4e-50 172.0 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD60297.1 - 5.1e-22 77.8 46.7 6.8e-22 77.4 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EMD60297.1 - 4.6 6.7 12.8 0.2 11.2 3.8 2.3 2 1 0 2 2 2 0 Mediator of CRAC channel activity SIR2 PF02146.12 EMD60298.1 - 1.2e-55 187.9 0.0 1.9e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF218 PF02698.12 EMD60298.1 - 0.077 12.4 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain Cofilin_ADF PF00241.15 EMD60299.1 - 1.1e-14 54.4 0.4 1.2e-14 54.2 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4128 PF13554.1 EMD60299.1 - 0.13 11.9 0.1 0.86 9.2 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function Homeobox_KN PF05920.6 EMD60301.1 - 7.2e-12 44.8 1.2 2e-11 43.4 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMD60301.1 - 2e-06 27.3 0.3 7.3e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 EMD60301.1 - 2e-05 24.3 0.1 0.29 10.9 0.0 3.9 3 1 0 3 3 3 2 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 EMD60301.1 - 0.00014 21.9 21.3 0.0025 18.0 1.5 4.7 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD60301.1 - 0.002 18.3 1.7 0.002 18.3 1.2 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD60301.1 - 2 8.8 6.1 7.6 7.0 0.1 3.6 3 1 0 3 3 3 0 Zinc-finger double domain Sugar_tr PF00083.19 EMD60302.1 - 1.8e-134 448.7 24.2 2.1e-134 448.5 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60302.1 - 4.6e-25 88.0 54.0 2.8e-22 78.8 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EPV_E5 PF08135.6 EMD60302.1 - 0.056 13.4 5.1 0.15 12.1 3.5 1.7 1 0 0 1 1 1 0 Major transforming protein E5 family DUF2237 PF09996.4 EMD60303.1 - 1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PUL PF08324.6 EMD60304.1 - 2.6e-46 157.5 0.2 3.6e-46 157.1 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EMD60304.1 - 1.5e-44 150.7 0.4 2.8e-44 149.8 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EMD60304.1 - 7.2e-42 139.8 9.6 6.4e-08 32.1 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD60304.1 - 0.0062 16.2 0.0 15 5.4 0.0 4.5 2 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region BTB PF00651.26 EMD60305.1 - 1.2e-13 51.0 0.1 7.7e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Sugar_tr PF00083.19 EMD60308.1 - 2.3e-77 260.5 20.1 2.7e-77 260.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60308.1 - 2.2e-25 89.1 19.4 2.2e-25 89.1 13.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EMD60309.1 - 1.2e-84 284.4 0.0 1.4e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_12 PF13087.1 EMD60312.1 - 9.2e-40 136.1 0.0 1.6e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMD60312.1 - 3.8e-25 88.8 2.0 7.3e-25 87.9 0.8 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMD60312.1 - 1.4e-09 37.8 0.0 7.3e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD60312.1 - 3.4e-09 36.3 0.0 1.3e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EMD60312.1 - 6.4e-06 25.8 0.0 0.0073 15.8 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EMD60312.1 - 0.00074 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 EMD60312.1 - 0.0011 18.8 1.3 0.0015 18.3 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMD60312.1 - 0.0043 16.0 0.0 0.035 13.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMD60312.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD60312.1 - 0.036 14.0 0.5 0.28 11.1 0.0 2.7 3 1 1 4 4 4 0 AAA ATPase domain DEAD PF00270.24 EMD60312.1 - 0.039 13.4 0.1 0.069 12.6 0.1 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase RuvB_N PF05496.7 EMD60312.1 - 0.074 12.0 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DOMON PF03351.12 EMD60316.1 - 0.00038 20.3 0.1 0.00071 19.5 0.1 1.5 1 1 0 1 1 1 1 DOMON domain EpsG PF14897.1 EMD60316.1 - 0.0058 15.6 9.6 0.011 14.6 6.7 1.4 1 0 0 1 1 1 1 EpsG family COX15-CtaA PF02628.10 EMD60316.1 - 0.28 9.9 12.4 0.5 9.1 8.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF2427 PF10348.4 EMD60316.1 - 2.2 7.8 11.6 0.15 11.6 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) VIT1 PF01988.14 EMD60316.1 - 3.6 7.0 8.3 3.7 6.9 0.1 2.4 2 0 0 2 2 2 0 VIT family TraL PF07178.6 EMD60317.1 - 0.041 13.8 0.2 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 TraL protein DUF897 PF05982.7 EMD60317.1 - 5 5.8 6.0 1.1 8.0 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF897) Isochorismatase PF00857.15 EMD60318.1 - 4.4e-41 140.7 0.0 5.8e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AA_permease_2 PF13520.1 EMD60319.1 - 2.1e-56 191.2 48.2 2.6e-56 190.9 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD60319.1 - 3.5e-21 75.0 42.2 4.8e-21 74.6 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease Herpes_U30 PF04523.8 EMD60320.1 - 0.0053 14.2 2.2 0.0077 13.7 1.5 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 AAA_13 PF13166.1 EMD60320.1 - 0.011 14.2 18.8 0.016 13.7 13.0 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 EMD60320.1 - 0.055 13.5 15.1 0.15 12.2 3.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MAD PF05557.8 EMD60320.1 - 0.13 10.3 25.3 0.2 9.7 17.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CENP-Q PF13094.1 EMD60320.1 - 0.36 10.8 26.9 0.47 10.4 7.8 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF869 PF05911.6 EMD60320.1 - 0.64 8.1 21.5 9.9 4.2 14.9 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2536 PF10750.4 EMD60320.1 - 1.3 8.6 5.2 6.5 6.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF4200 PF13863.1 EMD60320.1 - 2 8.3 28.2 0.095 12.6 5.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) AF0941-like PF14591.1 EMD60320.1 - 2.4 8.2 15.4 1.8 8.6 6.4 2.4 1 1 1 2 2 2 0 AF0941-like Striatin PF08232.7 EMD60320.1 - 3.4 7.9 20.4 1.6 9.0 4.6 3.3 1 1 2 3 3 3 0 Striatin family IncA PF04156.9 EMD60320.1 - 7.1 6.1 30.8 6 6.4 10.4 2.3 1 1 1 2 2 2 0 IncA protein IMS PF00817.15 EMD60324.1 - 1.1e-40 138.8 0.0 1.6e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMD60324.1 - 3.5e-12 46.3 0.0 1.3e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMD60324.1 - 0.025 14.6 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Caleosin PF05042.8 EMD60325.1 - 5.8e-59 198.5 0.0 7.3e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 EMD60325.1 - 0.064 13.1 3.1 1 9.4 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain CFEM PF05730.6 EMD60326.1 - 7.2e-14 51.3 11.4 1.6e-13 50.2 7.9 1.6 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.18 EMD60327.1 - 1.8e-18 66.3 1.9 3.5e-18 65.3 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD60327.1 - 7.8e-13 48.1 0.5 7.8e-13 48.1 0.4 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD60327.1 - 0.013 14.6 0.1 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fungal_trans PF04082.13 EMD60329.1 - 4.6e-18 65.0 0.1 7.2e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60329.1 - 5.5e-07 29.3 15.4 1.2e-06 28.3 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EMD60330.1 - 1.9e-06 27.3 0.0 2.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD60330.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD60330.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EMD60331.1 - 1.4e-59 200.1 0.0 2e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD60331.1 - 1.6e-20 72.8 0.0 1.9e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD60331.1 - 0.0016 18.3 0.1 0.0037 17.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMD60331.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EMD60331.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sugar_tr PF00083.19 EMD60332.1 - 8.3e-119 397.0 25.3 9.5e-119 396.9 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60332.1 - 1.3e-23 83.2 32.0 2e-23 82.7 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EMD60335.1 - 6.4e-27 94.0 0.4 1.3e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60335.1 - 2.4e-06 27.3 9.4 2.4e-06 27.3 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydrat_N PF13452.1 EMD60336.1 - 0.0025 17.5 0.0 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Zip PF02535.17 EMD60337.1 - 5.9e-44 150.3 17.7 5.9e-44 150.3 12.3 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter HRXXH PF13933.1 EMD60338.1 - 6.4e-102 340.1 0.0 9e-102 339.7 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Sporozoite_P67 PF05642.6 EMD60338.1 - 0.054 11.3 0.1 0.066 11.0 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GST_C PF00043.20 EMD60339.1 - 5.8e-12 45.4 0.1 9e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD60339.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD60339.1 - 8.1e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD60339.1 - 5.6e-06 26.4 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD60339.1 - 8e-05 23.0 0.2 0.00011 22.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD60339.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AhpC-TSA_2 PF13911.1 EMD60340.1 - 4.1e-10 39.6 0.0 6.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMD60340.1 - 3.8e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMD60340.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 2 1 0 2 2 2 0 Redoxin Y_phosphatase3 PF13350.1 EMD60341.1 - 6e-38 130.6 0.0 1.3e-37 129.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMD60341.1 - 1.7e-12 47.2 0.1 5.4e-12 45.6 0.1 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EMD60341.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TRAM_LAG1_CLN8 PF03798.11 EMD60342.1 - 2.8e-44 151.0 21.2 2.8e-44 151.0 14.7 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.6 EMD60342.1 - 4.7e-19 67.6 0.0 4.7e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Bax1-I PF01027.15 EMD60343.1 - 9.4e-50 169.0 30.9 1.1e-49 168.8 21.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 EMD60343.1 - 0.064 12.7 0.1 0.2 11.1 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Orbi_NS3 PF01616.11 EMD60343.1 - 0.13 11.2 1.9 0.64 8.9 0.3 2.2 2 0 0 2 2 2 0 Orbivirus NS3 7TMR-DISM_7TM PF07695.6 EMD60343.1 - 0.94 9.1 30.2 1.3 8.6 10.6 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DLIC PF05783.6 EMD60344.1 - 0.24 10.0 0.9 0.33 9.5 0.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Cys_knot PF00007.17 EMD60345.1 - 0.045 13.8 1.1 0.045 13.8 0.7 2.1 2 0 0 2 2 2 0 Cystine-knot domain Septin PF00735.13 EMD60347.1 - 2.1e-107 358.3 0.1 4.7e-107 357.2 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMD60347.1 - 5.7e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMD60347.1 - 5.9e-05 22.9 4.0 0.059 13.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EMD60347.1 - 0.00082 18.5 0.3 0.0023 17.1 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EMD60347.1 - 0.01 14.6 0.1 0.018 13.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EMD60347.1 - 0.019 15.4 0.4 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EMD60347.1 - 0.024 14.0 0.0 0.32 10.3 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD60347.1 - 0.045 13.8 0.4 0.13 12.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 EMD60347.1 - 0.063 12.3 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 AIG1 family GLE1 PF07817.8 EMD60347.1 - 0.13 11.1 0.7 0.21 10.5 0.5 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF3653 PF12375.3 EMD60347.1 - 0.19 11.9 1.9 3.2 8.0 0.4 2.7 3 0 0 3 3 2 0 Phage protein AAA_17 PF13207.1 EMD60347.1 - 0.27 12.0 4.3 0.67 10.7 0.1 2.8 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD60347.1 - 2.8 7.3 5.8 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 EMD60348.1 - 2.3e-08 33.5 2.9 0.0036 17.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EMD60348.1 - 0.03 13.4 0.0 4.2 6.3 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region PD40 PF07676.7 EMD60348.1 - 0.032 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EMD60348.1 - 0.12 11.4 0.0 0.44 9.5 0.0 1.8 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Carboxyl_trans PF01039.17 EMD60349.1 - 7.6e-143 476.4 0.3 1.1e-142 475.8 0.2 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Glyco_hydro_76 PF03663.9 EMD60349.1 - 5.3e-127 424.2 6.4 7.4e-127 423.7 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMD60349.1 - 0.061 12.3 6.1 0.17 10.8 4.3 1.6 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 YjeF_N PF03853.10 EMD60350.1 - 5.7e-35 120.4 0.0 6.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HeLo PF14479.1 EMD60352.1 - 7.1e-20 71.6 0.1 8.5e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EMD60353.1 - 3.9e-16 58.9 0.0 8.4e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EMD60353.1 - 1.8e-10 40.9 0.0 5.4e-06 26.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 EMD60353.1 - 9.5e-10 37.9 0.1 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.1 EMD60353.1 - 8.4e-06 26.1 0.0 1.1 9.8 0.0 5.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD60353.1 - 9.8e-05 22.4 0.0 0.0063 16.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 EMD60353.1 - 0.0002 21.0 0.1 1.6 8.6 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 EMD60353.1 - 0.0025 17.9 0.0 1.3 9.5 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ribosomal_S16 PF00886.14 EMD60354.1 - 7e-25 86.5 0.2 1.2e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 EMD60355.1 - 9.7e-92 307.5 18.6 1.5e-91 306.8 12.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RIC1 PF07064.8 EMD60355.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 RIC1 YfhO PF09586.5 EMD60355.1 - 1.3 6.9 7.9 0.49 8.3 3.7 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Dynactin_p22 PF07426.6 EMD60356.1 - 0.017 14.3 0.3 0.024 13.9 0.2 1.5 1 1 0 1 1 1 0 Dynactin subunit p22 Fib_alpha PF08702.5 EMD60356.1 - 0.069 13.2 0.7 0.12 12.4 0.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4611 PF15387.1 EMD60356.1 - 0.47 10.6 8.6 7.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.3 EMD60356.1 - 0.47 10.3 7.9 0.74 9.7 0.8 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SH3_1 PF00018.23 EMD60357.1 - 8e-10 37.9 0.1 1.4e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD60357.1 - 1.4e-07 30.8 0.0 2.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMD60357.1 - 1.7e-07 30.6 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.4 EMD60357.1 - 0.0018 18.1 0.7 0.029 14.3 0.4 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2069) DUF3311 PF11755.3 EMD60357.1 - 0.13 11.7 9.0 0.089 12.3 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) OsmC PF02566.14 EMD60358.1 - 1.7e-13 50.5 0.0 3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Neisseria_TspB PF05616.8 EMD60359.1 - 0.072 11.4 1.6 0.073 11.4 1.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Homeobox_KN PF05920.6 EMD60360.1 - 3.3e-17 61.8 0.5 8.3e-17 60.6 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMD60360.1 - 6.5e-09 35.2 0.8 1.4e-08 34.2 0.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EMD60360.1 - 0.00029 19.8 1.8 0.0043 16.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez zf-DHHC PF01529.15 EMD60362.1 - 8.9e-28 96.8 0.6 8.9e-28 96.8 0.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF1772 PF08592.6 EMD60362.1 - 0.16 11.7 3.8 0.1 12.3 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-RING_5 PF14634.1 EMD60365.1 - 0.23 11.1 6.5 0.42 10.3 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Arrestin_N PF00339.24 EMD60367.1 - 4.4e-06 26.5 0.2 2.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Annexin PF00191.15 EMD60368.1 - 3.6e-59 196.5 3.5 1.5e-16 60.0 0.1 4.3 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.3 EMD60368.1 - 0.056 13.0 2.5 2.2 7.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) TSLP PF15216.1 EMD60368.1 - 0.098 12.3 0.1 3.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Thymic stromal lymphopoietin PAT1 PF09770.4 EMD60370.1 - 0.83 7.8 29.1 0.99 7.5 20.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EMD60370.1 - 9.1 5.5 34.2 11 5.2 23.7 1.2 1 0 0 1 1 1 0 Vta1 like Gly_transf_sug PF04488.10 EMD60371.1 - 3.6e-13 49.8 0.0 1.2e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TPX2 PF06886.6 EMD60373.1 - 0.067 13.2 0.2 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DDE_Tnp_Tn3 PF01526.12 EMD60373.1 - 0.075 11.6 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain Glyco_transf_54 PF04666.8 EMD60374.1 - 5.1e-12 45.1 0.0 5.6e-08 31.8 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3716 PF12511.3 EMD60379.1 - 1.7e-09 37.1 3.1 3.3e-09 36.2 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HCO3_cotransp PF00955.16 EMD60380.1 - 8.3e-54 183.0 15.1 1.7e-32 112.7 5.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 EMD60381.1 - 4e-40 137.0 0.0 1.3e-39 135.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD60381.1 - 2.5e-26 91.3 0.3 1.1e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SET PF00856.23 EMD60381.1 - 1.1e-10 42.0 0.0 6.9e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 SET domain SNF2_N PF00176.18 EMD60381.1 - 3.8e-05 22.6 0.0 6.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pyridox_ox_2 PF12900.2 EMD60382.1 - 6.7e-37 126.4 0.0 9.4e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Vac_ImportDeg PF09783.4 EMD60383.1 - 4.4e-36 124.0 3.9 4.8e-24 84.8 0.8 2.9 2 1 0 2 2 2 2 Vacuolar import and degradation protein CAF-1_p150 PF11600.3 EMD60383.1 - 0.039 13.3 1.1 0.083 12.2 0.0 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Allene_ox_cyc PF06351.6 EMD60383.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Allene oxide cyclase DUF2524 PF10732.4 EMD60383.1 - 1.6 8.9 6.0 35 4.6 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF1786 PF08735.5 EMD60384.1 - 0.05 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) zf-LYAR PF08790.6 EMD60384.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger SelP_N PF04592.9 EMD60385.1 - 0.57 9.5 7.8 0.78 9.0 5.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region p450 PF00067.17 EMD60387.1 - 8.5e-66 222.3 0.0 1.1e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMP PF04927.7 EMD60388.1 - 1.2e-08 34.8 4.7 0.24 11.3 0.0 4.2 3 1 1 4 4 4 4 Seed maturation protein Arrestin_C PF02752.17 EMD60389.1 - 2.3e-11 43.9 0.1 6.7e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF4131 PF13567.1 EMD60390.1 - 0.31 10.4 2.2 0.54 9.6 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) bZIP_1 PF00170.16 EMD60391.1 - 1.7e-05 24.7 7.3 1.7e-05 24.7 5.1 2.0 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EMD60391.1 - 0.0041 16.8 7.4 0.016 15.0 5.1 2.0 1 0 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.1 EMD60391.1 - 0.84 8.5 8.2 0.13 11.1 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EMD60392.1 - 9.9e-15 54.9 3.7 9.9e-15 54.9 2.6 4.5 3 2 0 3 3 3 1 Stm1 IBR PF01485.16 EMD60393.1 - 3.6e-11 42.7 39.9 2.5e-06 27.2 1.6 4.7 4 0 0 4 4 4 3 IBR domain C1_4 PF07975.7 EMD60393.1 - 0.072 13.1 0.2 0.072 13.1 0.2 5.3 5 1 0 5 5 5 0 TFIIH C1-like domain Glyco_hydro_3 PF00933.16 EMD60394.1 - 1.7e-83 280.0 0.0 2.5e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD60394.1 - 1e-57 195.3 0.2 5.2e-57 192.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD60394.1 - 1.3e-14 53.8 0.0 3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Fork_head PF00250.13 EMD60396.1 - 2.6e-35 120.3 0.2 4.9e-35 119.4 0.2 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMD60396.1 - 2.3e-08 34.0 0.1 5.6e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain Ndufs5 PF10200.4 EMD60397.1 - 0.0044 16.9 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EMD60397.1 - 0.015 15.4 0.3 0.026 14.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.12 EMD60397.1 - 0.33 10.9 2.5 0.28 11.2 0.3 1.8 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb NT5C PF06941.7 EMD60398.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) LMBR1 PF04791.11 EMD60399.1 - 1.2e-32 113.1 2.4 2.4e-32 112.1 1.6 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein BMF PF15185.1 EMD60399.1 - 0.12 11.6 0.2 0.21 10.8 0.2 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis IncA PF04156.9 EMD60399.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 IncA protein Glutaredoxin PF00462.19 EMD60400.1 - 9.9e-19 67.0 0.0 1.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EMD60400.1 - 0.0099 16.1 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EMD60400.1 - 0.15 12.2 0.1 0.28 11.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain HEAT PF02985.17 EMD60401.1 - 4.8e-47 153.8 15.6 0.0058 16.6 0.1 13.1 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EMD60401.1 - 1.3e-33 115.1 4.5 2.8e-08 33.9 0.0 7.6 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EMD60401.1 - 2.1e-12 47.2 3.0 0.00022 21.5 0.1 7.2 5 3 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMD60401.1 - 7.5e-12 45.3 12.6 0.021 15.3 0.0 9.5 6 4 5 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EMD60401.1 - 5.2e-08 31.6 3.7 2.7e-07 29.3 0.6 3.2 2 1 1 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 EMD60401.1 - 0.00025 20.4 1.2 0.65 9.3 0.0 5.0 4 2 1 5 5 5 1 CLASP N terminal DUF2435 PF10363.4 EMD60401.1 - 0.00099 18.9 4.0 0.86 9.5 0.1 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 EMD60401.1 - 0.0019 17.9 1.7 2 8.3 0.0 5.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EMD60401.1 - 0.047 12.9 0.9 15 4.7 0.0 3.7 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 EMD60401.1 - 1.4 8.7 10.4 32 4.3 0.0 5.4 5 1 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 AA_permease_2 PF13520.1 EMD60402.1 - 5.8e-56 189.8 23.0 7.2e-56 189.5 15.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD60402.1 - 1.3e-25 89.7 20.0 1.8e-25 89.2 13.9 1.3 1 0 0 1 1 1 1 Amino acid permease Hydrophobin_2 PF06766.6 EMD60403.1 - 1.2e-25 88.9 13.1 1.5e-25 88.6 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Pkinase PF00069.20 EMD60407.1 - 6.6e-62 209.0 0.0 8e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60407.1 - 1.7e-36 125.6 0.0 2.2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60407.1 - 4.8e-09 35.5 0.0 7e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMD60407.1 - 0.15 10.8 0.1 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 B3_4 PF03483.12 EMD60408.1 - 1.3e-24 86.5 0.0 2.3e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EMD60408.1 - 6.6e-21 73.9 0.0 3.4e-18 65.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetase B5 domain Glyco_hydro_1 PF00232.13 EMD60409.1 - 7.1e-68 228.8 0.9 1.3e-34 119.2 0.1 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 GFO_IDH_MocA PF01408.17 EMD60411.1 - 1.1e-23 84.0 0.0 1.8e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMD60411.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 EMD60411.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMD60411.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EMD60411.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sdh5 PF03937.11 EMD60412.1 - 2.2e-23 81.7 0.1 4.6e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Glyco_hydro_53 PF07745.8 EMD60413.1 - 5e-108 360.8 0.0 5.7e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Ribosomal_S3_C PF00189.15 EMD60414.1 - 1.2e-16 60.6 0.1 2.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EMD60414.1 - 2.6e-12 46.1 0.1 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EMD60414.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Nuc_sug_transp PF04142.10 EMD60415.1 - 3.3e-09 36.1 2.0 5.5e-09 35.4 1.4 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EMD60415.1 - 7.1e-09 35.0 12.2 1.2e-08 34.2 8.4 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMD60415.1 - 9.6e-08 32.1 22.6 0.0004 20.4 2.0 2.7 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EMD60415.1 - 0.0005 19.7 23.4 0.0027 17.3 7.0 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family Cation_efflux PF01545.16 EMD60415.1 - 0.0068 15.5 21.2 0.21 10.6 14.7 2.3 1 1 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 EMD60416.1 - 8e-41 139.9 15.9 8e-41 139.9 11.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.11 EMD60416.1 - 0.28 9.8 6.5 0.18 10.4 0.2 2.2 2 0 0 2 2 2 0 BT1 family CbiQ PF02361.11 EMD60416.1 - 2 7.9 9.7 0.28 10.7 0.9 2.6 2 1 0 2 2 2 0 Cobalt transport protein DUF3376 PF11856.3 EMD60417.1 - 0.0058 16.0 0.5 0.0094 15.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) DUF16 PF01519.11 EMD60417.1 - 2 8.6 5.4 3.7 7.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Zn_clus PF00172.13 EMD60418.1 - 4.5e-07 29.6 12.6 4.5e-07 29.6 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3263 PF11662.3 EMD60418.1 - 0.073 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Flo11 PF10182.4 EMD60418.1 - 0.18 11.3 0.6 9.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Flo11 domain Nucleotid_trans PF03407.11 EMD60420.1 - 6e-09 35.9 0.2 1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EMD60420.1 - 2.7e-07 30.3 2.1 8.8e-07 28.6 1.5 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glycos_transf_2 PF00535.21 EMD60420.1 - 0.094 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Fungal_trans PF04082.13 EMD60421.1 - 2.6e-10 39.5 0.9 4.2e-10 38.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60421.1 - 2.9e-10 39.8 9.1 5.2e-10 39.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EMD60422.1 - 9.3e-05 22.0 0.0 0.00037 20.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD60422.1 - 0.12 12.0 0.7 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 F-box domain PALP PF00291.20 EMD60423.1 - 6.5e-69 232.4 1.0 8.1e-69 232.1 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S10 PF00450.17 EMD60424.1 - 1.2e-89 301.4 0.2 1.6e-89 300.9 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pro-kuma_activ PF09286.6 EMD60425.1 - 5.9e-38 130.1 0.0 1.8e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMD60425.1 - 9.5e-09 34.7 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family HAD_2 PF13419.1 EMD60426.1 - 1.2e-14 54.9 0.1 1.8e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD60426.1 - 1.3e-08 35.5 0.0 5.2e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD60426.1 - 1.4e-08 34.2 0.2 4.7e-08 32.6 0.2 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EMD60426.1 - 4.3e-06 27.0 0.0 6.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EMD60426.1 - 0.0029 16.9 0.0 0.69 9.2 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.9 EMD60426.1 - 0.073 12.4 0.1 8.1 5.7 0.0 2.6 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Glyco_hydro_18 PF00704.23 EMD60427.1 - 8.6e-78 262.1 12.2 1e-77 261.9 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DBC1 PF14443.1 EMD60427.1 - 0.029 13.8 0.5 0.094 12.2 0.3 1.8 1 1 1 2 2 2 0 DBC1 Glyco_hydro_28 PF00295.12 EMD60429.1 - 1.8e-118 395.2 25.3 2e-118 395.0 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EMD60429.1 - 1.5e-06 28.0 29.6 1.5e-06 28.0 20.5 2.6 2 2 1 3 3 3 1 Right handed beta helix region RnfC_N PF13375.1 EMD60429.1 - 0.077 12.7 1.2 0.2 11.3 0.9 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Melibiase PF02065.13 EMD60430.1 - 7.3e-154 512.2 0.0 9e-154 511.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase Scs3p PF10261.4 EMD60430.1 - 6.9e-67 224.9 3.6 9.7e-67 224.4 2.5 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF187 PF02638.10 EMD60430.1 - 3.1e-05 23.0 0.1 5.2e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 LVIVD PF08309.6 EMD60431.1 - 0.00031 19.6 3.6 0.47 9.4 0.9 4.3 5 0 0 5 5 5 2 LVIVD repeat Fungal_trans PF04082.13 EMD60432.1 - 1.7e-27 95.9 0.0 3.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60432.1 - 1.4e-08 34.4 7.4 2.4e-08 33.7 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L13 PF00572.13 EMD60433.1 - 4.2e-27 94.7 0.0 7.1e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 EMD60434.1 - 9.5e-72 241.6 0.0 1.2e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD60434.1 - 1.4e-15 57.9 0.0 2.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UAA PF08449.6 EMD60435.1 - 3.4e-67 226.4 13.1 6.3e-67 225.6 9.0 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMD60435.1 - 2.3e-06 27.6 26.4 0.00032 20.7 5.2 3.2 2 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMD60435.1 - 0.0005 19.2 4.6 0.0064 15.6 0.4 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter UPF0060 PF02694.10 EMD60435.1 - 0.033 14.1 0.5 0.033 14.1 0.3 2.5 3 1 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family TPT PF03151.11 EMD60435.1 - 1.1 8.9 21.3 0.04 13.5 7.0 2.7 2 2 0 2 2 2 0 Triose-phosphate Transporter family KH_1 PF00013.24 EMD60437.1 - 5.2e-39 131.6 8.6 5.3e-16 58.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMD60437.1 - 1.8e-30 104.0 11.2 1.7e-12 46.6 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMD60437.1 - 2.4e-10 39.8 9.7 0.0015 18.0 0.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 EMD60437.1 - 3.2e-08 33.0 5.8 0.062 12.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMD60437.1 - 0.00021 20.9 4.7 0.37 10.6 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EMD60437.1 - 0.025 14.0 0.1 3.9 6.9 0.0 3.0 3 0 0 3 3 3 0 dUTPase ADH_N PF08240.7 EMD60438.1 - 4.4e-29 100.4 1.6 4.4e-29 100.4 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD60438.1 - 2.7e-17 62.5 0.0 3.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMD60438.1 - 0.00068 19.2 0.4 0.00068 19.2 0.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.9 EMD60439.1 - 1.3e-23 82.8 0.7 1.6e-23 82.5 0.5 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EMD60439.1 - 0.0072 16.1 1.5 0.017 15.0 1.1 1.5 1 1 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.4 EMD60439.1 - 0.014 15.4 0.6 0.078 13.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 EMD60439.1 - 0.059 13.2 1.2 1.9 8.4 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family TPR_11 PF13414.1 EMD60440.1 - 1.9e-48 161.9 21.5 3.1e-18 65.1 0.4 5.9 3 2 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EMD60440.1 - 1e-40 135.6 19.8 2.4e-07 30.0 0.0 8.2 8 1 1 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMD60440.1 - 8.9e-36 118.9 20.8 1e-06 28.1 0.1 8.3 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMD60440.1 - 3.8e-31 107.0 10.5 3.2e-09 37.2 0.0 6.1 5 2 2 7 7 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMD60440.1 - 4.6e-28 97.3 16.1 3.6e-06 27.2 0.0 5.8 4 2 2 6 6 5 5 Tetratricopeptide repeat DnaJ PF00226.26 EMD60440.1 - 4.3e-27 93.6 4.4 1.6e-26 91.7 3.0 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 EMD60440.1 - 4e-23 79.7 13.1 0.00049 20.4 0.1 8.6 5 3 4 9 9 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMD60440.1 - 1.9e-20 72.5 12.6 0.00035 20.4 0.1 6.0 4 2 2 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EMD60440.1 - 5.1e-20 71.3 6.3 7.6e-08 32.3 0.3 3.5 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMD60440.1 - 6.2e-18 63.4 17.3 0.001 19.0 0.5 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMD60440.1 - 6.6e-17 61.1 4.8 3.7e-05 23.4 0.0 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD60440.1 - 6.2e-15 53.7 16.6 0.009 15.7 0.0 7.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD60440.1 - 6.6e-15 53.6 6.0 0.03 14.1 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMD60440.1 - 1.8e-12 46.7 9.4 0.049 14.1 0.1 7.9 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMD60440.1 - 1.3e-07 30.9 6.3 0.033 13.2 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMD60440.1 - 4.3e-07 29.7 1.1 0.17 12.4 0.0 4.6 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMD60440.1 - 1.5e-06 28.2 10.0 0.58 10.3 0.1 5.1 3 3 2 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD60440.1 - 2.3e-05 24.1 8.2 0.48 10.3 0.0 5.5 3 3 2 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EMD60440.1 - 9.9e-05 22.1 15.4 0.44 10.5 0.2 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat BTAD PF03704.12 EMD60440.1 - 0.00017 21.8 5.8 2.3 8.5 0.5 4.6 3 2 1 4 4 4 1 Bacterial transcriptional activator domain DUF3808 PF10300.4 EMD60440.1 - 0.00052 18.6 0.3 0.015 13.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.1 EMD60440.1 - 0.00085 19.5 3.6 0.069 13.3 0.5 3.7 2 2 0 2 2 2 1 Alkyl sulfatase dimerisation DUF3597 PF12200.3 EMD60440.1 - 0.0026 18.1 0.1 0.0026 18.1 0.1 2.8 3 1 1 4 4 2 1 Domain of unknown function (DUF3597) TPR_21 PF09976.4 EMD60440.1 - 0.0034 17.3 7.3 1.3 8.9 0.0 4.7 4 2 1 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 EMD60440.1 - 0.0052 16.6 1.9 8.4 6.6 0.0 4.6 5 0 0 5 5 3 0 PPR repeat FAT PF02259.18 EMD60440.1 - 0.063 12.2 3.2 0.14 11.1 1.1 2.4 2 1 0 2 2 2 0 FAT domain TPR_3 PF07720.7 EMD60440.1 - 0.076 12.8 1.4 1.4 8.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF928 PF06051.7 EMD60440.1 - 0.08 12.5 0.7 0.36 10.3 0.0 2.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF928) TOM20_plant PF06552.7 EMD60440.1 - 0.087 12.4 1.2 2 7.9 0.2 3.3 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EMD60440.1 - 0.11 12.4 9.8 0.99 9.3 0.4 4.8 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EMD60440.1 - 0.18 10.5 1.0 2.7 6.6 0.0 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2196 PF09962.4 EMD60441.1 - 2.9e-22 78.2 0.1 5.3e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) IncA PF04156.9 EMD60442.1 - 2.5e-07 30.4 8.7 2.5e-07 30.4 6.1 2.2 1 1 1 2 2 2 1 IncA protein PARG_cat PF05028.9 EMD60442.1 - 0.0041 16.4 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) BLOC1_2 PF10046.4 EMD60442.1 - 0.0049 16.9 16.7 0.012 15.7 0.7 3.4 2 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.1 EMD60442.1 - 0.0066 16.3 2.9 0.0066 16.3 2.0 4.1 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.2 EMD60442.1 - 0.037 13.8 26.0 0.029 14.2 4.9 2.9 2 1 0 2 2 2 0 Tropomyosin like dTDP_sugar_isom PF00908.12 EMD60442.1 - 0.039 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Hydrolase PF00702.21 EMD60442.1 - 0.069 13.5 0.5 10 6.4 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase KLRAQ PF10205.4 EMD60442.1 - 0.087 12.8 13.4 0.3 11.1 3.4 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF2422 PF10337.4 EMD60442.1 - 0.16 10.7 9.4 0.24 10.1 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) GAS PF13851.1 EMD60442.1 - 0.82 8.8 23.0 3 6.9 6.7 2.9 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EMD60442.1 - 1 9.1 13.9 0.52 10.1 2.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EMD60442.1 - 1.1 9.1 12.6 0.29 11.0 1.8 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 EMD60442.1 - 1.1 9.0 6.7 2.9 7.7 0.6 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 P4Ha_N PF08336.6 EMD60442.1 - 1.3 8.8 7.9 0.22 11.3 0.7 2.8 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF904 PF06005.7 EMD60442.1 - 2.7 8.3 23.7 2.5 8.4 0.3 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF904) DUF641 PF04859.7 EMD60442.1 - 3.3 7.4 16.9 0.72 9.6 1.9 3.7 3 1 0 3 3 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 EMD60442.1 - 3.7 7.4 26.6 0.24 11.2 1.8 3.7 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EMD60442.1 - 4.2 6.3 23.0 2.2 7.2 6.0 2.4 1 1 0 2 2 2 0 Autophagy protein Apg6 Gp-FAR-1 PF05823.7 EMD60442.1 - 7.8 6.4 12.5 9.3 6.1 1.3 3.3 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NPV_P10 PF05531.7 EMD60442.1 - 8.9 6.6 10.9 21 5.4 1.1 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ZZ PF00569.12 EMD60446.1 - 5.3e-17 61.0 58.6 2.7e-05 23.6 4.7 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type RRM_1 PF00076.17 EMD60447.1 - 8.2e-23 79.8 0.0 9.6e-13 47.5 0.0 3.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60447.1 - 5.7e-22 77.4 0.0 2.9e-11 43.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD60447.1 - 3.8e-09 36.2 0.1 0.0043 16.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon2 PF12745.2 EMD60447.1 - 0.33 10.0 10.4 0.57 9.2 7.2 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4551 PF15087.1 EMD60447.1 - 1.2 7.4 6.2 1.7 6.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AIM24 PF01987.12 EMD60448.1 - 7e-56 189.0 0.1 8.2e-56 188.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 EMD60449.1 - 7.2e-44 148.4 0.3 1.1e-43 147.7 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SPOC PF07744.8 EMD60449.1 - 0.049 14.1 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 SPOC domain Rotamase_3 PF13616.1 EMD60451.1 - 2.2e-16 60.1 0.1 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EMD60451.1 - 1.1e-15 58.1 1.0 1.2e-15 57.9 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EMD60451.1 - 0.0063 17.1 0.0 0.0096 16.5 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ank_2 PF12796.2 EMD60452.1 - 2.6e-22 78.9 0.0 5.8e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD60452.1 - 1.8e-14 52.7 0.0 0.0013 18.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMD60452.1 - 2.3e-14 53.1 0.0 3.4e-05 23.9 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD60452.1 - 4.4e-12 46.1 0.0 0.021 15.3 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD60452.1 - 2.8e-08 33.2 0.0 0.18 12.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Steroid_dh PF02544.11 EMD60453.1 - 4.1e-11 42.8 0.1 7.5e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ku PF02735.11 EMD60454.1 - 1.2e-27 96.6 0.0 2.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMD60454.1 - 1.5e-14 53.9 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EMD60454.1 - 5.1e-14 52.1 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like AAA_assoc PF14363.1 EMD60454.1 - 0.022 14.8 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA VWA PF00092.23 EMD60454.1 - 0.029 14.0 0.0 0.091 12.4 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain adh_short_C2 PF13561.1 EMD60456.1 - 1.9e-26 93.2 0.0 2.6e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD60456.1 - 6.3e-24 84.7 0.2 8.1e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD60456.1 - 5.7e-07 29.3 0.0 8.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3723 PF12520.3 EMD60456.1 - 0.2 10.0 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Formyl_trans_N PF00551.14 EMD60457.1 - 6e-39 133.4 0.6 8.1e-39 133.0 0.4 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EMD60457.1 - 9.4e-09 34.5 0.0 2.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EMD60457.1 - 4.8e-05 22.9 0.0 0.00029 20.4 0.0 2.2 2 0 0 2 2 2 1 ACT domain MGS PF02142.17 EMD60457.1 - 0.015 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain DUF837 PF05769.6 EMD60458.1 - 7.8e-05 22.2 0.9 0.00032 20.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF837) DivIC PF04977.10 EMD60458.1 - 0.27 10.7 14.4 0.49 9.9 0.1 3.8 4 0 0 4 4 4 0 Septum formation initiator ADIP PF11559.3 EMD60458.1 - 1.4 8.8 8.2 1.2 9.0 1.7 3.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1325 PF07039.6 EMD60459.1 - 1.3e-26 92.6 0.0 2.4e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Cortex-I_coil PF09304.5 EMD60459.1 - 0.0026 17.7 2.8 0.006 16.6 2.0 1.6 1 0 0 1 1 1 1 Cortexillin I, coiled coil Herpes_UL25 PF01499.11 EMD60459.1 - 0.047 11.9 2.3 0.073 11.3 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family PMI_typeI PF01238.16 EMD60460.1 - 2.8e-145 483.9 0.0 3.3e-145 483.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I P2 PF07194.6 EMD60460.1 - 0.02 14.7 0.5 5.4 6.9 0.1 2.5 2 0 0 2 2 2 0 P2 response regulator binding domain Glyco_transf_8 PF01501.15 EMD60461.1 - 2.5e-28 99.0 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EMD60461.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mito_carr PF00153.22 EMD60462.1 - 5.9e-59 195.7 0.2 1.7e-20 72.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DGOK PF05035.7 EMD60462.1 - 0.046 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Arf PF00025.16 EMD60463.1 - 1.4e-73 245.8 0.2 1.6e-73 245.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMD60463.1 - 1.4e-12 47.2 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMD60463.1 - 2e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMD60463.1 - 3.6e-12 45.6 2.0 9.7e-09 34.3 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMD60463.1 - 4.2e-11 42.4 0.0 5.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD60463.1 - 6.7e-08 33.0 0.0 9.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD60463.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMD60463.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Homeobox PF00046.24 EMD60464.1 - 4.1e-13 48.7 3.4 8.6e-13 47.7 2.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD60464.1 - 0.0013 18.3 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain NmrA PF05368.8 EMD60465.1 - 1.8e-06 27.3 0.0 6.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EMD60465.1 - 0.0012 18.8 1.0 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD60465.1 - 0.0083 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DDE_Tnp_ISAZ013 PF07592.6 EMD60465.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain COPIIcoated_ERV PF07970.7 EMD60469.1 - 4.2e-31 108.2 0.2 2e-29 102.8 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMD60469.1 - 6.4e-19 67.7 0.1 1.2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_S26 PF10502.4 EMD60470.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EMD60470.1 - 0.006 16.1 0.1 0.05 13.2 0.1 2.3 1 1 0 1 1 1 1 Peptidase S24-like Cupin_8 PF13621.1 EMD60471.1 - 5.5e-62 209.5 0.1 6.3e-62 209.3 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMD60471.1 - 0.0003 20.1 0.0 0.033 13.4 0.0 2.6 3 0 0 3 3 3 2 Cupin superfamily protein DNA_ligase_A_M PF01068.16 EMD60473.1 - 9.4e-46 155.7 0.4 3.1e-45 154.0 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD60473.1 - 6.1e-39 133.6 0.0 1.2e-38 132.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMD60473.1 - 4.9e-17 62.1 0.0 1.9e-16 60.2 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EMD60473.1 - 6.6e-08 32.5 0.0 8.2e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Complex1_49kDa PF00346.14 EMD60473.1 - 0.016 14.2 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit nec1 PF10379.4 EMD60474.1 - 0.099 11.9 0.2 0.33 10.2 0.1 1.8 1 1 1 2 2 2 0 Virulence protein nec1 4HBT_3 PF13622.1 EMD60475.1 - 0.01 15.6 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MG1 PF11974.3 EMD60475.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Snf7 PF03357.16 EMD60476.1 - 2e-37 128.2 18.7 2e-37 128.2 13.0 1.8 1 1 1 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EMD60476.1 - 0.021 12.7 2.8 0.027 12.3 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EMD60476.1 - 0.087 12.2 3.6 0.13 11.6 2.5 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Peptidase_S46 PF10459.4 EMD60476.1 - 0.14 10.5 5.5 0.17 10.2 3.8 1.1 1 0 0 1 1 1 0 Peptidase S46 YlqD PF11068.3 EMD60476.1 - 2.6 8.0 17.8 4.4 7.3 7.1 2.1 1 1 1 2 2 2 0 YlqD protein DSBA PF01323.15 EMD60476.1 - 3.6 7.0 6.3 12 5.4 4.4 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Dynamin_N PF00350.18 EMD60477.1 - 3.6e-14 52.9 0.5 1.2e-13 51.2 0.0 2.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EMD60477.1 - 1.9e-08 34.2 0.0 6.4e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_2 PF13639.1 EMD60477.1 - 3.7e-07 29.8 6.7 1.3e-06 28.1 4.7 1.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD60477.1 - 6e-07 29.4 0.4 1.2e-06 28.4 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger GTP_EFTU PF00009.22 EMD60477.1 - 4.2e-06 26.3 0.3 2.4e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-RING_5 PF14634.1 EMD60477.1 - 9.2e-05 22.0 1.1 0.00025 20.7 0.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD60477.1 - 0.00011 21.7 1.2 0.00021 20.8 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD60477.1 - 0.003 17.1 3.5 0.007 16.0 2.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD60477.1 - 0.0035 17.3 1.8 0.0035 17.3 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EMD60477.1 - 0.01 13.5 6.3 0.03 12.0 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2921) DUF2205 PF10224.4 EMD60477.1 - 0.014 14.9 0.5 0.048 13.2 0.4 1.8 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Wzy_C PF04932.10 EMD60477.1 - 0.018 14.8 0.0 1.1 8.9 0.0 2.8 2 1 1 3 3 2 0 O-Antigen ligase AAA_18 PF13238.1 EMD60477.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EMD60477.1 - 0.052 12.3 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EMD60477.1 - 0.083 12.4 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EMD60477.1 - 0.12 12.8 0.0 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein zf-Apc11 PF12861.2 EMD60477.1 - 0.23 11.3 1.0 0.5 10.2 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rhomboid PF01694.17 EMD60478.1 - 5.6e-40 136.7 7.5 5.6e-40 136.7 5.2 1.8 2 0 0 2 2 2 1 Rhomboid family zf-C2H2_4 PF13894.1 EMD60479.1 - 8e-10 38.3 26.3 0.11 12.8 0.2 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD60479.1 - 1.6e-08 34.3 34.2 0.073 13.4 0.9 6.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD60479.1 - 0.025 14.4 23.3 1 9.3 0.2 5.7 6 1 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 EMD60479.1 - 0.033 14.3 15.3 0.59 10.4 0.2 4.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMD60479.1 - 0.066 13.5 35.3 0.14 12.5 0.3 6.4 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 EMD60479.1 - 0.076 13.1 29.9 1.4 9.0 0.3 5.3 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_2 PF12674.2 EMD60479.1 - 0.16 12.3 4.0 0.21 11.9 2.1 1.8 1 1 0 1 1 1 0 Putative zinc ribbon domain zf-BED PF02892.10 EMD60479.1 - 0.26 11.0 0.1 0.26 11.0 0.1 4.2 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.3 EMD60479.1 - 1.2 9.3 21.5 2.1 8.5 1.2 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Cyanate_lyase PF02560.9 EMD60480.1 - 8.1e-34 114.9 0.0 1.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EMD60480.1 - 0.00042 20.0 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EMD60480.1 - 0.0045 17.0 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EMD60480.1 - 0.018 15.2 0.0 0.061 13.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain PLDc_2 PF13091.1 EMD60481.1 - 3e-15 56.1 0.0 3.5e-06 26.7 0.0 3.9 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EMD60481.1 - 5.6e-11 41.8 1.3 5.7e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF3431 PF11913.3 EMD60482.1 - 1.7e-89 299.1 0.0 1.7e-89 299.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Patatin PF01734.17 EMD60483.1 - 5.7e-13 49.2 0.2 1.2e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 EMD60483.1 - 9.8e-06 25.9 0.0 3.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMD60483.1 - 0.00015 21.0 0.0 0.00077 18.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMD60483.1 - 0.0035 17.2 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EMD60483.1 - 0.0077 15.3 0.4 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EMD60483.1 - 0.0088 16.1 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EMD60483.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EMD60483.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rsa3 PF14615.1 EMD60483.1 - 0.063 12.5 1.0 5.3 6.4 0.0 2.8 3 0 0 3 3 3 0 Ribosome-assembly protein 3 UPF0449 PF15136.1 EMD60483.1 - 0.31 11.2 1.6 1.6 8.9 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3665 PF12427.3 EMD60483.1 - 0.35 10.2 1.5 0.97 8.8 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase F-box PF00646.28 EMD60485.1 - 0.002 17.7 0.4 0.0045 16.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD60485.1 - 0.057 13.1 0.4 0.15 11.7 0.3 1.8 1 0 0 1 1 1 0 F-box-like Ino80_Iec3 PF14612.1 EMD60486.1 - 0.055 13.5 0.7 0.07 13.1 0.5 1.1 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Amino_oxidase PF01593.19 EMD60487.1 - 5.1e-44 151.0 2.1 3.4e-26 92.3 0.9 2.8 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD60487.1 - 2.4e-12 46.6 0.1 5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD60487.1 - 5e-06 26.8 0.5 4.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD60487.1 - 7.3e-06 25.1 0.5 0.00079 18.4 0.9 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD60487.1 - 4.3e-05 23.6 0.4 0.00031 20.8 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD60487.1 - 6.9e-05 21.8 0.2 0.00013 20.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD60487.1 - 0.0001 20.9 0.7 0.0021 16.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMD60487.1 - 0.00025 20.2 0.3 0.00043 19.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMD60487.1 - 0.00037 20.4 0.5 0.0088 15.9 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD60487.1 - 0.0011 18.1 1.2 0.0011 18.1 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMD60487.1 - 0.0086 15.8 5.4 0.84 9.3 0.0 3.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EMD60487.1 - 0.045 13.3 0.4 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMD60487.1 - 0.092 11.8 0.1 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EMD60487.1 - 0.14 11.0 2.0 0.21 10.4 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A PP2C PF00481.16 EMD60488.1 - 1e-64 218.4 0.1 5.3e-52 176.7 0.1 3.3 2 1 0 2 2 2 2 Protein phosphatase 2C GAF_2 PF13185.1 EMD60489.1 - 9.1e-11 42.4 0.0 1.9e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EMD60489.1 - 1.4e-05 25.2 0.0 2.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EMD60489.1 - 0.0095 16.0 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 GAF domain Abhydrolase_6 PF12697.2 EMD60490.1 - 7.2e-05 22.7 0.0 9.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60490.1 - 0.0043 16.6 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60490.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DSPn PF14671.1 EMD60491.1 - 3e-42 143.9 0.0 8.9e-39 132.6 0.0 3.2 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EMD60491.1 - 5.5e-15 55.1 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD60491.1 - 4.3e-06 26.2 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMD60491.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EMD60491.1 - 0.17 11.3 0.1 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SET PF00856.23 EMD60492.1 - 0.0017 18.6 0.0 0.0047 17.2 0.0 1.7 2 0 0 2 2 2 1 SET domain Fungal_trans PF04082.13 EMD60493.1 - 4.1e-34 117.6 0.4 9.1e-34 116.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60493.1 - 2.5e-09 36.8 11.5 5e-09 35.9 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RcsC PF09456.5 EMD60493.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) KTI12 PF08433.5 EMD60494.1 - 8e-88 294.1 0.0 9e-88 293.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EMD60494.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD60494.1 - 0.0013 19.5 0.0 0.0021 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EMD60494.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 EMD60494.1 - 0.067 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pex16 PF08610.5 EMD60495.1 - 0.043 12.8 2.1 0.049 12.6 1.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Period_C PF12114.3 EMD60495.1 - 0.14 11.6 10.5 0.17 11.5 7.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PAT1 PF09770.4 EMD60495.1 - 0.26 9.4 15.9 0.29 9.3 11.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 EMD60495.1 - 0.45 9.4 3.1 0.55 9.1 2.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FliJ PF02050.11 EMD60495.1 - 2.7 8.0 11.1 8.2 6.5 7.9 1.6 1 1 1 2 2 2 0 Flagellar FliJ protein DUF605 PF04652.11 EMD60495.1 - 2.9 7.1 18.7 3.3 7.0 13.0 1.0 1 0 0 1 1 1 0 Vta1 like DUF1754 PF08555.5 EMD60496.1 - 8.4e-15 55.1 11.3 8.4e-15 55.1 7.8 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Ribosomal_S8e PF01201.17 EMD60496.1 - 2.2 8.4 8.4 0.49 10.5 2.4 1.9 2 0 0 2 2 2 0 Ribosomal protein S8e Herpes_DNAp_acc PF04929.7 EMD60496.1 - 2.6 6.9 9.9 3.4 6.5 6.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AA_permease PF00324.16 EMD60497.1 - 2.4e-120 402.1 32.8 2.9e-120 401.8 22.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD60497.1 - 4.5e-37 127.6 39.4 7.7e-37 126.8 27.3 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3154 PF11351.3 EMD60497.1 - 0.17 11.6 1.3 0.33 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Zn_clus PF00172.13 EMD60498.1 - 0.00011 22.0 10.2 0.0002 21.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAGA-Tad1 PF12767.2 EMD60498.1 - 9 5.8 19.1 0.61 9.7 5.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Kinetochor_Ybp2 PF08568.5 EMD60499.1 - 2.7e-139 465.3 0.2 3.3e-139 465.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin LSM PF01423.17 EMD60500.1 - 4e-18 64.7 0.0 5.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Cyclin_N PF00134.18 EMD60501.1 - 1.1e-44 150.9 0.4 2.5e-44 149.8 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMD60501.1 - 1.4e-31 108.8 0.1 3.6e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EMD60502.1 - 0.00034 20.4 12.1 0.00062 19.6 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EMD60502.1 - 0.0021 17.2 0.2 0.0021 17.2 0.1 3.0 3 0 0 3 3 3 1 Histone chaperone domain CHZ Transglut_core PF01841.14 EMD60503.1 - 3.6e-12 46.4 0.0 7.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EMD60503.1 - 0.01 15.1 0.0 0.058 12.6 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like domain YjeF_N PF03853.10 EMD60504.1 - 2.3e-36 124.9 0.0 3.8e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EMD60504.1 - 8.3e-09 35.9 1.1 8.3e-09 35.9 0.8 2.5 2 1 0 2 2 2 1 FDF domain DUF3209 PF11483.3 EMD60504.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF1749 PF08538.5 EMD60505.1 - 1.7e-88 296.4 0.0 1.9e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EMD60505.1 - 3.2e-09 36.9 0.0 9.9e-09 35.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD60505.1 - 6.6e-07 29.1 0.0 1.3e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EMD60505.1 - 0.005 15.8 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EMD60505.1 - 0.0077 15.8 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EMD60505.1 - 0.0099 15.2 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EMD60505.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase F-box PF00646.28 EMD60506.1 - 0.011 15.3 0.1 1.8 8.3 0.2 2.6 2 0 0 2 2 2 0 F-box domain PRANC PF09372.5 EMD60506.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Dak1 PF02733.12 EMD60507.1 - 1.4e-117 391.9 5.0 2.1e-117 391.3 3.5 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMD60507.1 - 1.7e-44 151.5 0.3 4e-44 150.3 0.2 1.7 1 0 0 1 1 1 1 DAK2 domain DUF1442 PF07279.6 EMD60507.1 - 0.34 9.9 3.1 1.2 8.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) LSM PF01423.17 EMD60508.1 - 1.2e-17 63.1 0.1 1.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain GATA PF00320.22 EMD60509.1 - 7.1e-05 22.0 2.2 0.017 14.4 0.2 2.8 2 0 0 2 2 2 2 GATA zinc finger Zn_clus PF00172.13 EMD60509.1 - 0.54 10.2 19.3 0.24 11.3 10.3 2.6 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMD60510.1 - 2.3e-25 89.4 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD60510.1 - 3.5e-24 85.9 0.0 4.1e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD60510.1 - 5e-13 49.1 0.0 6.7e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EMD60510.1 - 0.031 14.1 0.4 0.063 13.1 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2507 PF10702.4 EMD60510.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) PFU PF09070.6 EMD60510.1 - 0.092 12.7 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) SurE PF01975.12 EMD60511.1 - 2.8e-45 154.0 0.0 3.9e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Med2 PF11214.3 EMD60512.1 - 0.044 13.8 5.3 0.055 13.5 2.8 1.9 1 1 0 1 1 1 0 Mediator complex subunit 2 MCPVI PF02993.9 EMD60512.1 - 2.6 8.1 16.5 2.9 7.9 5.0 2.4 2 0 0 2 2 2 0 Minor capsid protein VI RRM_1 PF00076.17 EMD60514.1 - 5.9e-57 189.2 0.0 9.1e-22 76.4 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60514.1 - 9.9e-43 143.9 0.0 1.8e-14 53.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD60514.1 - 4e-32 109.8 0.0 3.7e-10 39.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD60514.1 - 4.8e-05 23.0 0.0 2.7 7.8 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EMD60514.1 - 0.029 14.2 0.0 7 6.6 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) YodA PF09223.6 EMD60514.1 - 0.11 12.1 0.2 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 YodA lipocalin-like domain PIF1 PF05970.9 EMD60515.1 - 2.8e-17 62.7 0.0 3.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EMD60515.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD60515.1 - 9.7e-05 22.0 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EMD60515.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EMD60515.1 - 0.0029 17.7 0.7 0.014 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EMD60515.1 - 0.0085 15.7 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EMD60515.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EMD60515.1 - 0.013 14.1 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 EMD60515.1 - 0.018 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EMD60515.1 - 0.03 13.2 1.2 0.048 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EMD60515.1 - 0.058 12.9 3.7 0.16 11.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMD60515.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EMD60515.1 - 0.079 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EMD60515.1 - 0.097 11.8 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 EMD60515.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.0 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain ATP-synt_C PF00137.16 EMD60516.1 - 4.5e-33 112.9 28.4 1.8e-19 69.3 5.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EMD60516.1 - 0.12 11.4 1.5 1.7 7.7 0.6 2.1 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 EMD60516.1 - 0.34 10.4 4.9 0.096 12.2 1.0 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Myotub-related PF06602.9 EMD60518.1 - 3e-122 407.8 0.0 3.8e-122 407.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EMD60518.1 - 0.091 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family HD_assoc PF13286.1 EMD60518.1 - 0.13 12.6 0.1 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Ribosomal_L7Ae PF01248.21 EMD60519.1 - 6.9e-27 92.7 0.0 8.1e-27 92.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMD60519.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EMD60519.1 - 0.0037 17.0 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain NUDIX PF00293.23 EMD60520.1 - 8.4e-06 25.4 0.0 8.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain GFO_IDH_MocA PF01408.17 EMD60521.1 - 9.1e-11 42.3 0.4 7.2e-10 39.4 0.3 2.5 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Pterin_bind PF00809.17 EMD60521.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme Exonuc_VII_S PF02609.11 EMD60521.1 - 0.057 13.1 0.5 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit DHDPS PF00701.17 EMD60522.1 - 2.6e-34 118.1 0.0 3e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 EMD60523.1 - 2e-26 92.4 0.0 3.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60523.1 - 2.7e-09 36.7 11.2 5.3e-09 35.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 EMD60523.1 - 0.014 13.8 2.4 0.021 13.2 1.7 1.1 1 0 0 1 1 1 0 Per os infectivity Fungal_trans_2 PF11951.3 EMD60523.1 - 0.019 13.6 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain GST_N_3 PF13417.1 EMD60525.1 - 5.5e-14 52.1 0.0 9.4e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD60525.1 - 1.5e-11 44.0 0.0 3.1e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD60525.1 - 1.6e-11 44.0 0.0 3.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD60525.1 - 1.3e-10 41.2 0.0 5.3e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD60525.1 - 9.1e-10 38.2 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD60525.1 - 8.6e-08 32.5 0.0 1.6e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BAG PF02179.11 EMD60527.1 - 5.4e-21 74.4 0.1 9.4e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 BAG domain DUF3602 PF12223.3 EMD60529.1 - 6.3e-14 52.1 9.1 2.6e-06 27.7 0.2 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EMD60529.1 - 0.069 12.8 3.9 0.81 9.3 0.0 2.7 1 1 1 3 3 3 0 GTP1/OBG zf-C2H2 PF00096.21 EMD60530.1 - 4.3e-06 26.7 15.0 2.4e-05 24.3 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD60530.1 - 1.5e-05 24.9 8.5 1.6e-05 24.9 2.3 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD60530.1 - 0.0011 18.9 0.7 0.0028 17.7 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMD60530.1 - 0.0013 18.9 0.7 0.0013 18.9 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger Imm1 PF14430.1 EMD60530.1 - 0.096 12.8 0.1 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm1 zf-TRAF PF02176.13 EMD60530.1 - 3.7 8.0 7.7 0.39 11.1 1.7 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger IU_nuc_hydro PF01156.14 EMD60531.1 - 2e-81 273.6 0.0 2.3e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ferric_reduct PF01794.14 EMD60532.1 - 4.5e-18 65.5 10.1 4.5e-18 65.5 7.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD60532.1 - 6e-13 48.9 0.0 2.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD60532.1 - 1.4e-08 34.5 0.0 4.4e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 EMD60532.1 - 0.087 12.9 0.0 0.65 10.1 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD60532.1 - 0.16 12.5 0.1 33 5.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ribosomal_L7Ae PF01248.21 EMD60533.1 - 2.8e-26 90.8 0.9 5.4e-26 89.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.20 EMD60534.1 - 1.9e-38 132.0 0.0 3.5e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60534.1 - 2.1e-31 108.9 0.0 3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60534.1 - 0.0044 16.0 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD60534.1 - 0.0065 16.2 0.6 1.9 8.1 0.0 3.0 3 1 1 4 4 4 2 Phosphotransferase enzyme family LRR_4 PF12799.2 EMD60535.1 - 1.7e-16 59.4 3.0 0.23 11.1 0.0 7.6 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMD60535.1 - 4.8e-10 38.4 12.1 8.6 6.7 0.0 10.3 11 0 0 11 11 11 1 Leucine Rich repeat F-box-like PF12937.2 EMD60535.1 - 3.5e-09 36.2 0.5 1.4e-08 34.3 0.0 2.4 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 EMD60535.1 - 4.3e-08 32.7 14.6 0.01 15.5 0.0 6.3 3 1 6 9 9 9 5 Leucine rich repeat LRR_1 PF00560.28 EMD60535.1 - 4.4e-08 32.0 19.3 14 6.1 0.0 10.8 10 2 1 11 11 11 1 Leucine Rich Repeat F-box PF00646.28 EMD60535.1 - 4.3e-05 23.0 1.4 0.0012 18.4 0.1 3.6 4 0 0 4 4 4 1 F-box domain LRR_7 PF13504.1 EMD60535.1 - 0.026 14.6 25.5 3.1 8.3 0.0 9.4 10 0 0 10 10 10 0 Leucine rich repeat PTE PF02126.13 EMD60535.1 - 0.047 12.6 0.2 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Phosphotriesterase family Ste50p-SAM PF09235.5 EMD60535.1 - 1.1 9.3 23.2 26 4.9 0.3 8.1 4 2 6 10 10 10 0 Ste50p, sterile alpha motif zf-rbx1 PF12678.2 EMD60536.1 - 0.021 14.9 3.3 0.081 13.0 2.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger DUF2361 PF10153.4 EMD60537.1 - 3.4e-29 101.3 11.4 3.4e-29 101.3 7.9 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Cytochrom_C552 PF02335.10 EMD60537.1 - 0.0022 16.7 3.3 0.0022 16.7 2.3 1.4 2 0 0 2 2 2 1 Cytochrome c552 DUF2680 PF10925.3 EMD60537.1 - 0.71 9.7 4.3 0.25 11.2 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) YfdX PF10938.3 EMD60537.1 - 1.7 8.2 8.6 2.1 8.0 0.5 2.5 2 1 0 2 2 2 0 YfdX protein Glyco_hydro_47 PF01532.15 EMD60538.1 - 2.3e-135 451.7 0.0 2.6e-135 451.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Adaptin_N PF01602.15 EMD60539.1 - 4.1e-143 477.4 1.7 4.9e-143 477.2 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EMD60539.1 - 1e-23 83.8 0.1 2.5e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EMD60539.1 - 8.9e-05 22.6 6.6 0.21 11.8 0.0 4.9 5 1 0 5 5 5 2 HEAT repeats TIP120 PF08623.5 EMD60539.1 - 0.002 17.7 1.7 0.079 12.5 0.0 3.0 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EMD60539.1 - 0.0027 17.6 1.6 28 5.1 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 EMD60539.1 - 0.015 15.0 1.1 82 3.2 0.1 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EMD60539.1 - 0.018 14.4 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal Cnd1 PF12717.2 EMD60539.1 - 0.047 13.5 5.0 0.13 12.0 0.4 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MBOAT PF03062.14 EMD60540.1 - 1.1e-35 123.3 18.0 1.1e-35 123.3 12.5 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMD60540.1 - 0.0033 17.4 1.5 0.0097 15.9 1.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3074 PF11274.3 EMD60541.1 - 5e-62 208.8 1.2 2.9e-60 203.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.14 EMD60541.1 - 1.4e-05 24.5 0.0 3.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 START domain CAF-1_p150 PF11600.3 EMD60541.1 - 0.0015 17.9 35.0 0.0015 17.9 24.3 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Exonuc_VII_L PF02601.10 EMD60541.1 - 0.019 14.1 22.0 0.031 13.4 15.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3373 PF11853.3 EMD60541.1 - 1.9 6.9 9.2 3.7 5.9 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4407 PF14362.1 EMD60541.1 - 2.7 6.8 15.8 4.2 6.2 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FSH1 PF03959.8 EMD60542.1 - 4.6e-19 68.7 0.0 5.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Tenui_NCP PF04876.7 EMD60542.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein CoA_transf_3 PF02515.12 EMD60544.1 - 1.6e-26 92.7 0.0 3.2e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III SOG2 PF10428.4 EMD60544.1 - 0.24 10.0 0.9 0.36 9.4 0.2 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Fungal_trans PF04082.13 EMD60545.1 - 3.5e-27 94.9 0.3 9.3e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60545.1 - 1.5e-06 27.9 13.5 2.7e-06 27.1 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIS_C PF01096.13 EMD60546.1 - 1.4e-19 69.3 5.3 1.4e-19 69.3 3.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMD60546.1 - 0.00027 20.5 8.4 0.043 13.5 0.2 3.4 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Acetone_carb_G PF08882.6 EMD60546.1 - 0.00049 20.0 2.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetone carboxylase gamma subunit Zn_Tnp_IS1595 PF12760.2 EMD60546.1 - 0.0092 15.7 5.1 0.73 9.6 1.0 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Terminase_GpA PF05876.7 EMD60546.1 - 0.036 12.4 1.9 0.044 12.1 1.3 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF4268 PF14088.1 EMD60546.1 - 0.078 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) PhnA_Zn_Ribbon PF08274.7 EMD60546.1 - 0.086 12.6 3.0 2.1 8.2 0.1 2.6 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.3 EMD60546.1 - 0.09 12.1 0.3 0.09 12.1 0.2 1.6 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain C1_4 PF07975.7 EMD60546.1 - 0.83 9.7 9.1 3 7.9 0.3 3.1 2 2 0 2 2 2 0 TFIIH C1-like domain DUF2387 PF09526.5 EMD60546.1 - 1.1 9.1 6.3 0.78 9.7 0.5 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-Mss51 PF13824.1 EMD60546.1 - 1.8 8.4 5.6 1.3 8.9 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 EMD60546.1 - 2 8.3 7.2 0.86 9.4 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 EMD60546.1 - 3.7 8.0 12.4 5.4 7.4 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double domain C1_3 PF07649.7 EMD60546.1 - 4.6 7.3 6.3 2.4 8.2 0.1 2.9 3 0 0 3 3 3 0 C1-like domain IBR PF01485.16 EMD60546.1 - 8.1 6.4 11.8 3.9e+03 -2.2 8.2 3.1 1 1 0 1 1 1 0 IBR domain Ank_2 PF12796.2 EMD60547.1 - 6.7e-13 48.7 0.1 3e-10 40.3 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD60547.1 - 1.4e-12 47.4 0.5 1.5e-06 28.2 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD60547.1 - 5.6e-12 44.8 0.0 0.00025 20.7 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD60547.1 - 6.1e-10 39.3 0.1 1.2e-05 25.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD60547.1 - 4.3e-08 32.6 0.1 0.033 14.4 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat TFIIS_M PF07500.9 EMD60547.1 - 0.13 12.3 0.1 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain SF3b10 PF07189.6 EMD60548.1 - 3.4e-36 122.9 0.0 3.8e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Vinculin PF01044.14 EMD60549.1 - 0.0026 15.8 0.0 0.0029 15.6 0.0 1.0 1 0 0 1 1 1 1 Vinculin family Co_AT_N PF12557.3 EMD60549.1 - 0.5 10.3 8.6 0.074 12.9 3.1 1.8 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Abhydrolase_6 PF12697.2 EMD60550.1 - 1.5e-19 70.8 1.8 8.6e-19 68.3 1.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD60550.1 - 3.2e-06 26.9 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60550.1 - 1.9e-05 24.3 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Homeobox PF00046.24 EMD60551.1 - 5.7e-11 41.8 0.1 1.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD60551.1 - 0.0003 20.4 0.2 0.0003 20.4 0.1 3.2 4 0 0 4 4 4 1 Homeobox KN domain zf-C2H2_4 PF13894.1 EMD60551.1 - 0.0038 17.4 1.2 0.0038 17.4 0.8 7.6 5 2 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD60551.1 - 0.036 14.4 0.8 0.036 14.4 0.5 7.1 6 2 1 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMD60551.1 - 0.081 13.0 0.2 0.081 13.0 0.2 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EMD60551.1 - 0.62 9.7 12.4 0.54 9.9 0.2 4.6 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif UTP15_C PF09384.5 EMD60552.1 - 2.7e-44 150.4 0.1 5.7e-44 149.3 0.1 1.6 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EMD60552.1 - 6.3e-26 89.2 0.9 5.2e-07 29.3 0.0 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_L22 PF00237.14 EMD60553.1 - 8e-17 61.0 0.1 8.6e-09 35.2 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e DUF643 PF04867.7 EMD60553.1 - 0.75 10.2 3.9 0.67 10.3 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF643) RRM_1 PF00076.17 EMD60554.1 - 5.3e-47 157.3 0.4 3.7e-16 58.5 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60554.1 - 4.5e-37 125.8 0.0 2.2e-10 40.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD60554.1 - 5.2e-27 93.4 0.2 2.1e-09 37.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD60554.1 - 2.3e-08 33.6 0.1 0.059 13.1 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMD60554.1 - 0.00038 20.1 0.0 3.4 7.4 0.0 4.1 4 0 0 4 4 4 2 Limkain b1 Lsm_interact PF05391.6 EMD60554.1 - 0.00048 19.4 0.2 0.0013 18.0 0.1 1.7 1 0 0 1 1 1 1 Lsm interaction motif F-box-like_2 PF13013.1 EMD60554.1 - 0.026 14.2 0.0 0.14 11.8 0.0 2.3 1 0 0 1 1 1 0 F-box-like domain Vps55 PF04133.9 EMD60555.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 55 PID_2 PF14719.1 EMD60556.1 - 0.064 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Ferric_reduct PF01794.14 EMD60557.1 - 1.1e-20 74.0 5.9 1.1e-20 74.0 4.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD60557.1 - 6.4e-18 65.1 0.0 5.4e-11 42.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD60557.1 - 2.2e-14 53.1 0.0 7.5e-13 48.2 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NUDIX PF00293.23 EMD60559.1 - 1e-05 25.1 0.1 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain 3HCDH_N PF02737.13 EMD60560.1 - 5.6e-49 166.2 0.0 1.1e-48 165.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMD60560.1 - 6.8e-13 48.8 0.0 2e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EMD60560.1 - 3.9e-08 32.9 0.0 1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMD60560.1 - 6.9e-07 29.1 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SGL PF08450.7 EMD60560.1 - 0.00074 18.9 0.0 0.45 9.8 0.0 2.9 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region ApbA PF02558.11 EMD60560.1 - 0.0014 18.0 0.0 0.01 15.3 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 EMD60560.1 - 0.0034 17.9 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_2 PF03446.10 EMD60560.1 - 0.0042 16.9 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMD60560.1 - 0.0059 15.7 0.0 0.018 14.1 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMD60560.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lactonase PF10282.4 EMD60560.1 - 0.014 14.5 0.0 2.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller AlaDh_PNT_C PF01262.16 EMD60560.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.18 EMD60560.1 - 0.038 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Ldl_recept_b PF00058.12 EMD60560.1 - 0.045 14.0 5.6 4 7.8 0.1 4.8 5 0 0 5 5 4 0 Low-density lipoprotein receptor repeat class B F420_oxidored PF03807.12 EMD60560.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EMD60560.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_transf_3 PF02515.12 EMD60561.1 - 8e-28 96.9 0.6 2.4e-27 95.4 0.1 1.8 2 0 0 2 2 2 1 CoA-transferase family III M16C_assoc PF08367.6 EMD60561.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16C associated Peptidase_M14 PF00246.19 EMD60563.1 - 1.1e-61 208.9 0.0 2.4e-61 207.7 0.0 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase GTP_EFTU PF00009.22 EMD60564.1 - 1.3e-57 194.3 0.0 2.1e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMD60564.1 - 5.6e-37 125.9 0.1 1.7e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD60564.1 - 5.1e-16 58.5 3.1 5.1e-16 58.5 2.2 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD60564.1 - 0.00044 20.2 0.4 0.0014 18.5 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMD60564.1 - 0.00056 19.4 1.0 0.00056 19.4 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PDZ PF00595.19 EMD60564.1 - 0.079 13.1 0.6 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Pkinase PF00069.20 EMD60566.1 - 9.4e-59 198.6 0.1 1.3e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60566.1 - 1.1e-21 77.0 0.0 1.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60566.1 - 7.6e-08 31.6 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD60566.1 - 0.00015 20.8 0.2 0.00033 19.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD60566.1 - 0.00034 20.4 0.2 0.066 12.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EMD60566.1 - 0.001 18.4 0.3 0.0023 17.2 0.2 1.6 1 1 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EMD60566.1 - 0.012 15.9 0.0 0.47 10.8 0.0 3.3 3 1 0 3 3 3 0 PAS domain Seadorna_VP7 PF07387.6 EMD60566.1 - 0.32 9.7 0.1 0.53 9.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pex14_N PF04695.8 EMD60566.1 - 6.6 6.7 11.2 15 5.6 1.8 3.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M41 PF01434.13 EMD60567.1 - 1.6e-75 253.2 0.2 4e-75 251.9 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EMD60567.1 - 8.9e-42 142.4 0.1 2.7e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMD60567.1 - 4.6e-11 42.8 0.1 1.4e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EMD60567.1 - 0.0051 16.5 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD60567.1 - 0.0074 16.4 1.3 1.4 9.0 0.2 3.0 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 EMD60567.1 - 0.013 14.2 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 EMD60567.1 - 0.057 14.2 0.0 0.2 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD60567.1 - 0.075 12.1 0.1 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EMD60567.1 - 0.077 12.9 0.6 1.3 8.9 0.3 2.4 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 EMD60567.1 - 0.092 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMD60567.1 - 0.13 12.0 2.4 0.15 11.8 0.5 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 EMD60567.1 - 0.18 11.1 1.5 0.73 9.2 0.4 2.3 1 1 1 2 2 2 0 AAA domain NYD-SP28 PF14772.1 EMD60567.1 - 0.45 10.6 3.3 8.7 6.4 0.2 2.5 2 0 0 2 2 2 0 Sperm tail APH PF01636.18 EMD60568.1 - 1.2e-11 44.8 0.1 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD60568.1 - 0.00063 18.9 0.0 0.0015 17.7 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EMD60568.1 - 0.00099 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EMD60568.1 - 0.0036 16.0 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) UcrQ PF02939.11 EMD60570.1 - 5.4e-27 93.4 0.0 7e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 UcrQ family DUF2074 PF09847.4 EMD60570.1 - 0.02 13.6 0.0 0.023 13.4 0.0 1.0 1 0 0 1 1 1 0 Predicted permease (DUF2074) CFEM PF05730.6 EMD60571.1 - 3.4e-11 42.7 1.7 6.1e-11 41.9 1.1 1.4 1 0 0 1 1 1 1 CFEM domain DUF1793 PF08760.6 EMD60574.1 - 1.3e-72 243.1 0.5 8.1e-72 240.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Methyltransf_23 PF13489.1 EMD60576.1 - 2.5e-10 40.2 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD60576.1 - 1.9e-08 34.6 0.0 4.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD60576.1 - 6.6e-07 29.7 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD60576.1 - 3.8e-06 26.5 0.0 1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD60576.1 - 0.029 13.4 0.0 0.062 12.4 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.8 EMD60577.1 - 1.1e-136 456.5 0.2 1.2e-136 456.2 0.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.4 EMD60577.1 - 0.011 14.7 6.1 0.57 9.2 0.7 3.0 2 0 0 2 2 2 0 Mu-like prophage protein Com FAD_binding_7 PF03441.9 EMD60578.1 - 1.1e-89 300.4 0.2 1.5e-89 299.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMD60578.1 - 3.4e-38 131.0 0.0 6.3e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Glyco_transf_8 PF01501.15 EMD60580.1 - 2e-39 135.4 0.0 3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMD60580.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EMD60580.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase VHP PF02209.14 EMD60580.1 - 0.11 12.1 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain Prok-E2_E PF14462.1 EMD60580.1 - 0.27 10.8 1.4 0.59 9.7 0.3 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family E Peptidase_M20 PF01546.23 EMD60581.1 - 5.4e-33 114.0 0.0 7.6e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD60581.1 - 3.5e-13 49.2 0.0 5.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MRP-L20 PF12824.2 EMD60582.1 - 4.4e-51 173.1 5.9 5.5e-51 172.7 4.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EMD60582.1 - 0.097 12.4 0.2 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Neugrin Mitochondr_Som1 PF11093.3 EMD60583.1 - 4.7e-20 71.1 0.0 5.4e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 EMD60584.1 - 9.7e-22 76.7 0.7 9.7e-22 76.7 0.5 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EMD60584.1 - 4e-07 29.6 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF3153 PF11353.3 EMD60588.1 - 0.27 10.6 0.8 0.42 10.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) WD40 PF00400.27 EMD60589.1 - 5.7e-36 121.1 8.7 4.5e-09 35.8 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.2 EMD60589.1 - 3.6e-10 39.3 0.2 7.1e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EMD60589.1 - 3.2e-08 32.1 0.4 0.0021 16.2 0.0 3.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 EMD60589.1 - 2.4e-06 27.0 0.0 4.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EMD60589.1 - 0.00011 21.7 1.0 0.00089 18.7 0.7 2.3 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EMD60589.1 - 0.059 13.6 3.3 0.67 10.3 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain DUF4064 PF13273.1 EMD60591.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Abhydrolase_5 PF12695.2 EMD60592.1 - 6.5e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD60592.1 - 1.1e-05 25.4 0.3 2.4e-05 24.3 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD60592.1 - 8.3e-05 22.2 0.7 0.00016 21.3 0.0 1.8 2 1 0 2 2 2 1 PGAP1-like protein UPF0227 PF05728.7 EMD60592.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EMD60592.1 - 0.0053 16.3 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMD60592.1 - 0.024 14.2 0.0 0.066 12.8 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EMD60592.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Macoilin PF09726.4 EMD60592.1 - 0.085 11.1 21.5 0.12 10.6 14.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Borrelia_P83 PF05262.6 EMD60592.1 - 0.72 8.0 24.4 1 7.5 16.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 EMD60592.1 - 2.9 7.6 24.8 5.1 6.8 17.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3584 PF12128.3 EMD60592.1 - 4.3 4.5 29.5 6.6 3.9 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SAPS PF04499.10 EMD60592.1 - 9.9 4.6 13.9 14 4.1 9.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BATS PF06968.8 EMD60594.1 - 1.5e-27 95.2 0.0 3.9e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EMD60594.1 - 2e-15 57.3 0.2 5.3e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.16 EMD60595.1 - 4.1e-40 137.8 0.0 4.7e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD60595.1 - 6.4e-06 24.6 0.0 1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMD60595.1 - 5.2e-05 22.1 0.0 0.02 13.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_3 PF00202.16 EMD60595.1 - 0.0024 16.7 0.0 0.0037 16.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMD60595.1 - 0.036 13.2 0.1 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase OKR_DC_1 PF01276.15 EMD60595.1 - 0.093 11.2 0.1 0.26 9.7 0.1 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.16 EMD60596.1 - 8.7e-40 136.6 0.0 8.8e-23 80.6 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EMD60596.1 - 1.6e-31 109.4 0.0 3.4e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD60596.1 - 0.058 13.5 0.3 1.2 9.3 0.0 3.0 4 0 0 4 4 4 0 RNA helicase CbiA PF01656.18 EMD60596.1 - 0.064 12.6 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cullin PF00888.17 EMD60596.1 - 0.16 10.4 0.0 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 Cullin family ADH_zinc_N PF00107.21 EMD60598.1 - 5.7e-14 51.7 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD60598.1 - 4e-12 45.8 0.0 7.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ALIX_LYPXL_bnd PF13949.1 EMD60600.1 - 0.26 10.1 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF2235 PF09994.4 EMD60601.1 - 2.9e-76 256.4 3.5 1.1e-74 251.2 2.4 2.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PLDc_2 PF13091.1 EMD60602.1 - 6.9e-21 74.3 0.0 2.8e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMD60602.1 - 0.0032 17.2 0.2 0.2 11.4 0.0 2.8 3 0 0 3 3 3 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EMD60602.1 - 0.046 12.6 0.2 1.2 8.0 0.0 2.9 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB Herpes_pp38 PF04846.8 EMD60603.1 - 1.5 8.1 4.2 3.8 6.8 2.9 1.7 1 1 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Stb3 PF10330.4 EMD60604.1 - 2.6e-33 113.5 0.0 6.3e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein Nop14 PF04147.7 EMD60604.1 - 0.3 8.9 3.3 0.38 8.6 2.3 1.1 1 0 0 1 1 1 0 Nop14-like family BNIP2 PF12496.3 EMD60604.1 - 0.6 10.2 6.0 0.38 10.9 2.4 1.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Topoisom_bac PF01131.15 EMD60606.1 - 5.4e-89 298.8 0.0 6.3e-83 278.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EMD60606.1 - 1.5e-18 66.6 0.0 3.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.7 EMD60607.1 - 7.5e-32 110.5 9.6 9.1e-32 110.2 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EMD60607.1 - 0.06 13.5 0.7 0.31 11.2 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ECR1_N PF14382.1 EMD60608.1 - 4.3e-10 38.7 0.1 9.8e-10 37.5 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EMD60608.1 - 0.0023 17.8 0.0 0.039 13.8 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 UPF0546 PF10639.4 EMD60610.1 - 1.1e-41 141.2 1.0 1.3e-41 140.9 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EMD60610.1 - 0.00029 20.8 5.5 0.0037 17.3 1.5 2.8 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EMD60610.1 - 0.14 12.3 7.5 0.041 14.0 2.7 2.0 2 1 0 2 2 2 0 Multidrug resistance efflux transporter PhyH PF05721.8 EMD60611.1 - 5.8e-55 186.5 0.0 7.5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ketoacyl-synt PF00109.21 EMD60612.1 - 3e-74 249.6 0.0 6e-74 248.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMD60612.1 - 4.3e-62 209.0 0.2 6.5e-59 198.6 0.1 3.8 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 EMD60612.1 - 1.2e-53 182.5 0.1 2.1e-53 181.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMD60612.1 - 2.8e-48 164.5 0.0 5.2e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMD60612.1 - 6.7e-46 156.2 0.0 5.5e-44 150.0 0.0 3.4 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD60612.1 - 6.7e-36 122.7 0.0 1.6e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EMD60612.1 - 1.3e-06 29.3 0.0 5.6e-06 27.2 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD60612.1 - 5.6e-06 26.0 0.0 1.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMD60612.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EMD60612.1 - 0.0002 20.9 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EMD60612.1 - 0.003 16.5 0.3 0.0071 15.3 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF3180 PF11377.3 EMD60612.1 - 0.015 15.1 1.5 0.049 13.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) ACP_syn_III PF08545.5 EMD60612.1 - 0.029 14.0 1.5 0.076 12.6 1.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 EMD60612.1 - 0.17 10.7 0.0 0.35 9.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EMD60613.1 - 1.1e-36 126.2 18.3 1.1e-36 126.2 12.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Mito_carr PF00153.22 EMD60614.1 - 1.7e-55 184.7 12.6 6.8e-19 67.3 0.1 3.5 3 1 1 4 4 4 3 Mitochondrial carrier protein Bd3614_N PF14442.1 EMD60614.1 - 0.092 12.7 0.8 0.66 9.9 0.0 2.4 2 1 1 3 3 3 0 Bd3614-like deaminase N-terminal Ank PF00023.25 EMD60615.1 - 1.1e-27 94.4 5.1 3.4e-09 36.0 0.0 4.5 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMD60615.1 - 2.8e-24 85.2 1.3 2.3e-12 47.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD60615.1 - 3.1e-21 73.3 0.9 7.9e-07 28.7 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMD60615.1 - 1.2e-17 63.8 4.5 9.7e-11 41.8 0.2 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD60615.1 - 1.1e-13 50.8 7.1 8.2e-05 22.7 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) peroxidase PF00141.18 EMD60616.1 - 4.4e-18 65.6 0.2 7.2e-18 64.9 0.2 1.2 1 0 0 1 1 1 1 Peroxidase tRNA-synt_1f PF01921.13 EMD60617.1 - 0.022 13.4 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_L24e PF01246.15 EMD60620.1 - 1.2e-29 101.9 2.9 1.2e-29 101.9 2.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.4 EMD60620.1 - 3.4 7.7 7.5 8.6 6.4 0.5 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DnaJ PF00226.26 EMD60621.1 - 1.1e-07 31.4 0.1 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EMD60621.1 - 5.7e-06 26.1 0.0 6.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 Glyco_hydro_61 PF03443.9 EMD60622.1 - 2.4e-59 200.8 0.2 2.8e-59 200.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF718 PF05336.8 EMD60624.1 - 3.9e-37 126.2 0.3 4.4e-37 126.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) CLU PF13236.1 EMD60625.1 - 6.4e-80 267.7 0.0 1.1e-79 266.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EMD60625.1 - 1.7e-48 164.7 1.0 9.9e-48 162.2 0.0 2.6 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EMD60625.1 - 1e-32 111.8 17.8 8.7e-13 48.0 0.7 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 EMD60625.1 - 1.3e-26 92.4 0.7 3.5e-26 91.1 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EMD60625.1 - 5.8e-22 76.8 1.6 7.1e-06 25.7 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD60625.1 - 6.5e-08 32.1 2.0 4.8e-05 22.9 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMD60625.1 - 2.5e-05 23.8 2.8 3.4 7.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 EMD60625.1 - 0.00055 19.6 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.23 EMD60625.1 - 0.015 14.8 1.9 0.46 10.1 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD60625.1 - 0.016 14.9 0.3 2.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD60625.1 - 0.017 14.8 2.7 0.23 11.3 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD60625.1 - 0.027 14.6 0.9 34 4.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.9 EMD60625.1 - 1.5 6.7 19.2 2.5 6.0 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 EMD60625.1 - 3.2 6.3 10.1 5.9 5.4 7.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EMD60625.1 - 3.6 5.1 10.5 5.3 4.6 7.3 1.2 1 0 0 1 1 1 0 Ycf1 TATR PF03430.8 EMD60625.1 - 4 5.9 11.8 9.9 4.6 8.2 1.6 1 0 0 1 1 1 0 Trans-activating transcriptional regulator NOA36 PF06524.7 EMD60625.1 - 5.9 6.0 10.1 11 5.1 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 EMD60625.1 - 5.9 6.1 25.8 19 4.5 17.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 EMD60625.1 - 7.4 4.9 13.9 15 3.9 9.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_16 PF13191.1 EMD60626.1 - 5.8e-06 26.4 1.2 8.4e-05 22.6 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMD60626.1 - 0.00043 20.0 0.1 0.00087 19.0 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EMD60626.1 - 0.026 14.0 0.1 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD60626.1 - 0.057 12.8 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EMD60626.1 - 0.11 12.1 0.2 0.4 10.3 0.0 1.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD60626.1 - 0.19 11.9 2.3 1.8 8.7 0.9 2.8 2 1 0 2 2 2 0 AAA domain P16-Arc PF04699.9 EMD60629.1 - 8e-58 194.7 0.0 9.1e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UBA_4 PF14555.1 EMD60631.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain TatC PF00902.13 EMD60631.1 - 1.2 8.5 7.5 2.7 7.3 5.1 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) MARVEL PF01284.18 EMD60631.1 - 1.6 8.5 13.5 6.8 6.5 9.2 1.9 1 1 0 1 1 1 0 Membrane-associating domain Yip1 PF04893.12 EMD60631.1 - 2.8 7.4 11.6 6.4 6.2 8.1 1.6 1 1 0 1 1 1 0 Yip1 domain Chalcone PF02431.10 EMD60632.1 - 1.1e-53 181.6 0.0 1.5e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase MAGE PF01454.14 EMD60633.1 - 5.5e-37 127.0 0.0 6.7e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 MAGE family DUF4149 PF13664.1 EMD60634.1 - 2e-22 79.1 12.4 2.2e-22 79.0 3.6 3.2 2 2 1 3 3 3 1 Domain of unknown function (DUF4149) Methyltransf_31 PF13847.1 EMD60635.1 - 8.8e-20 70.8 0.0 1.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD60635.1 - 2.7e-18 66.5 0.0 4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD60635.1 - 5.6e-08 33.1 0.0 9.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD60635.1 - 2.4e-06 27.5 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD60635.1 - 1.1e-05 25.2 0.1 7.9e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMD60635.1 - 7e-05 22.5 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD60635.1 - 0.00045 19.3 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EMD60635.1 - 0.00055 20.3 0.0 0.0012 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD60635.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMD60635.1 - 0.0021 18.4 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD60635.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 EMD60635.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EMD60635.1 - 0.059 13.4 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 EMD60635.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF4267 PF14087.1 EMD60636.1 - 1.2e-23 82.8 0.1 1.5e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Kei1 PF08552.6 EMD60636.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMCO5 PF14992.1 EMD60637.1 - 0.031 13.4 12.1 0.065 12.3 8.4 1.6 1 0 0 1 1 1 0 TMCO5 family HIRAN PF08797.6 EMD60637.1 - 0.12 12.3 0.2 8.9 6.2 0.0 2.6 2 0 0 2 2 2 0 HIRAN domain SlyX PF04102.7 EMD60637.1 - 0.71 10.2 10.7 0.35 11.2 1.3 2.8 1 1 1 2 2 2 0 SlyX CENP-Q PF13094.1 EMD60637.1 - 1 9.3 17.3 0.15 12.0 7.9 2.4 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1843 PF08898.5 EMD60637.1 - 1.2 9.2 4.0 1.3 9.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF465 PF04325.8 EMD60637.1 - 6.6 6.5 10.7 4.3 7.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Adap_comp_sub PF00928.16 EMD60638.1 - 6.6e-51 172.9 0.0 8.8e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMD60638.1 - 4.9e-05 23.0 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.1 EMD60639.1 - 0.00012 22.0 0.4 0.00012 22.0 0.2 1.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4536) DUF4588 PF15251.1 EMD60640.1 - 0.0016 18.4 4.1 0.0039 17.1 2.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) peroxidase PF00141.18 EMD60642.1 - 1.3e-30 106.6 0.0 1.9e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EMD60642.1 - 1.6e-05 24.6 0.0 4.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Glyco_hydro_61 PF03443.9 EMD60643.1 - 1.5e-53 181.8 0.1 2.4e-53 181.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMD60643.1 - 1.5e-10 40.5 7.9 3.5e-10 39.3 5.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Med13_N PF11597.3 EMD60643.1 - 1.4 7.4 7.3 0.22 10.1 1.0 2.2 2 1 0 2 2 2 0 Mediator complex subunit 13 N-terminal Cu-oxidase_3 PF07732.10 EMD60644.1 - 7.7e-34 115.9 1.1 7.7e-34 115.9 0.8 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EMD60644.1 - 2.5e-33 115.2 0.2 2.5e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD60644.1 - 9.5e-31 106.1 11.2 8.9e-29 99.7 3.4 3.4 3 0 0 3 3 3 2 Multicopper oxidase adh_short PF00106.20 EMD60645.1 - 6.4e-24 84.7 0.1 1.3e-23 83.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD60645.1 - 1.1e-19 71.2 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD60645.1 - 2.8e-08 33.6 0.1 6.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD60645.1 - 0.00056 19.9 0.2 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMD60645.1 - 0.00092 18.7 0.8 0.0027 17.1 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMD60645.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Duffy_binding PF05424.6 EMD60645.1 - 0.013 15.3 0.1 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Duffy binding domain 3Beta_HSD PF01073.14 EMD60645.1 - 0.025 13.2 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EMD60645.1 - 0.026 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 EMD60645.1 - 0.03 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EMD60645.1 - 0.03 13.9 0.1 0.077 12.6 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNase_H PF00075.19 EMD60646.1 - 1.8e-05 25.0 0.1 3.6e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 RNase H DUF3018 PF11455.3 EMD60646.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) DUF364 PF04016.7 EMD60647.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) PVL_ORF50 PF07768.6 EMD60647.1 - 0.14 12.1 6.7 0.27 11.2 4.6 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family EBP PF05241.7 EMD60648.1 - 3.9e-08 32.5 7.2 6.7e-08 31.7 5.0 1.6 1 1 0 1 1 1 1 Emopamil binding protein Cellulase PF00150.13 EMD60651.1 - 9.3e-11 41.4 0.3 1.5e-10 40.7 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMD60651.1 - 0.021 15.2 0.0 0.12 12.8 0.0 2.2 3 0 0 3 3 3 0 Sugar-binding cellulase-like Whi5 PF08528.6 EMD60652.1 - 2.2e-05 23.8 2.2 4.3e-05 23.0 1.5 1.5 1 0 0 1 1 1 1 Whi5 like PRP4 PF08799.6 EMD60652.1 - 0.16 11.2 0.6 0.31 10.3 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pal1 PF08316.6 EMD60653.1 - 1.9e-46 158.0 6.2 5.1e-46 156.6 0.7 3.0 2 1 0 2 2 2 1 Pal1 cell morphology protein Med31 PF05669.7 EMD60654.1 - 2.4e-34 117.1 0.1 2.7e-34 116.9 0.1 1.0 1 0 0 1 1 1 1 SOH1 RabGAP-TBC PF00566.13 EMD60655.1 - 5.2e-31 107.7 0.2 8.8e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Shadoo PF14999.1 EMD60655.1 - 0.24 11.2 3.3 1.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Rad51 PF08423.6 EMD60656.1 - 6e-07 28.6 0.1 9.7e-07 27.9 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EMD60656.1 - 3.5e-05 23.0 0.0 0.00027 20.1 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein A_deamin PF02137.13 EMD60657.1 - 5.4e-62 210.1 0.0 6.5e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NT-C2 PF10358.4 EMD60658.1 - 1.5e-32 112.0 0.0 2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 EMD60659.1 - 3e-36 124.8 0.6 4.5e-36 124.2 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NMT1 PF09084.6 EMD60660.1 - 4.4e-75 251.9 0.0 2.4e-74 249.5 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EMD60660.1 - 1.7e-08 34.1 0.2 0.011 15.0 0.1 3.0 2 1 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.2 EMD60660.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HET PF06985.6 EMD60661.1 - 1e-22 80.8 0.0 2.9e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Homeobox_KN PF05920.6 EMD60662.1 - 2.7e-12 46.1 0.3 6.2e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMD60662.1 - 2.9e-11 42.8 0.3 5.8e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Ribosomal_L37ae PF01780.14 EMD60662.1 - 1.8 8.4 4.3 6.1 6.7 1.3 2.8 2 1 0 2 2 2 0 Ribosomal L37ae protein family zf-Sec23_Sec24 PF04810.10 EMD60662.1 - 4.6 6.8 12.2 6.7 6.3 0.2 4.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger LysM PF01476.15 EMD60663.1 - 7.5e-11 41.7 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain RelB_N PF12910.2 EMD60663.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Hydrophobin PF01185.13 EMD60664.1 - 1.1e-12 48.1 8.6 1.5e-12 47.7 6.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin RRM_6 PF14259.1 EMD60664.1 - 0.04 13.8 0.0 8.9 6.3 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyoxalase PF00903.20 EMD60665.1 - 5.8e-08 32.7 0.4 6e-07 29.4 0.3 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMD60665.1 - 0.00051 20.6 0.0 0.0015 19.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain PhaP_Bmeg PF09602.5 EMD60666.1 - 0.05 13.4 1.0 0.25 11.1 0.5 2.1 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RVT_1 PF00078.22 EMD60671.1 - 2.9e-06 26.8 2.6 3.2e-06 26.6 1.8 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2469 PF10611.4 EMD60671.1 - 0.0062 16.8 0.2 0.01 16.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) POT1 PF02765.12 EMD60671.1 - 0.11 12.3 0.5 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Plasmid_parti PF01672.11 EMD60671.1 - 0.18 12.2 6.4 0.54 10.7 4.4 1.8 1 1 0 1 1 1 0 Putative plasmid partition protein DDE_1 PF03184.14 EMD60672.1 - 8e-24 83.9 0.0 8e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD60672.1 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SelB-wing_2 PF09106.6 EMD60674.1 - 0.041 13.8 0.1 0.092 12.6 0.0 1.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix SF3a60_bindingd PF12108.3 EMD60674.1 - 0.46 10.0 4.5 0.31 10.6 0.6 2.4 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Na_Ca_ex PF01699.19 EMD60677.1 - 1.6e-39 134.6 35.9 2.9e-21 75.5 10.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Polysacc_deac_1 PF01522.16 EMD60678.1 - 5.1e-27 93.9 0.0 6.8e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EMD60678.1 - 7e-06 25.1 0.0 9e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Pmp3 PF01679.12 EMD60679.1 - 1.9e-18 65.8 6.1 2.3e-18 65.6 4.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sec39 PF08314.6 EMD60684.1 - 6.8e-171 569.7 0.2 7.9e-171 569.5 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF1469 PF07332.6 EMD60686.1 - 0.056 13.1 1.0 0.096 12.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4098 PF13345.1 EMD60686.1 - 0.12 12.3 15.8 0.15 12.0 1.5 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4098) DUF4451 PF14616.1 EMD60687.1 - 8e-33 112.8 0.2 1.6e-32 111.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) NmrA PF05368.8 EMD60688.1 - 8.3e-12 44.8 0.2 2.9e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family Fun_ATP-synt_8 PF05933.8 EMD60689.1 - 5.7e-18 64.6 7.8 8e-18 64.2 5.4 1.2 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) MFS_1 PF07690.11 EMD60690.1 - 8.7e-38 129.9 20.4 2.8e-35 121.6 2.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CCSMST1 PF15013.1 EMD60690.1 - 0.15 11.9 0.5 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 CCSMST1 family DUF1772 PF08592.6 EMD60691.1 - 1e-27 96.5 3.7 1.5e-27 96.0 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 EMD60691.1 - 0.057 12.5 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 ETC_C1_NDUFA5 PF04716.9 EMD60692.1 - 0.018 14.5 0.1 0.042 13.3 0.1 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region F-box-like PF12937.2 EMD60693.1 - 1.1e-13 50.5 0.6 2.2e-13 49.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EMD60693.1 - 9.2e-12 43.7 19.5 0.64 10.2 0.0 8.9 9 0 0 9 9 9 6 Leucine Rich repeat F-box PF00646.28 EMD60693.1 - 4e-10 39.0 0.1 1.3e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EMD60693.1 - 5e-07 29.1 9.1 1 9.0 0.0 6.0 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD60693.1 - 2.8e-05 23.7 13.0 0.068 12.9 0.1 5.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EMD60693.1 - 0.00013 21.5 17.5 5.2 7.4 0.4 8.1 7 2 0 7 7 7 2 Leucine Rich Repeat PRANC PF09372.5 EMD60693.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 PRANC domain 2OG-FeII_Oxy_2 PF13532.1 EMD60694.1 - 3.1e-14 53.2 0.0 1e-12 48.2 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMD60694.1 - 0.00054 20.2 0.0 0.0021 18.3 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DOMON PF03351.12 EMD60695.1 - 1.7e-07 31.2 0.7 2.8e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EMD60695.1 - 0.013 15.3 15.0 0.031 14.0 10.4 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 EB1 PF03271.12 EMD60697.1 - 6.8e-17 61.2 0.7 6.8e-17 61.2 0.5 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 EMD60697.1 - 7.9e-08 32.3 0.9 1.3e-07 31.6 0.6 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Phi-29_GP3 PF05435.6 EMD60697.1 - 0.049 12.8 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Syja_N PF02383.13 EMD60697.1 - 0.05 12.3 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain ASFV_J13L PF05568.6 EMD60698.1 - 0.061 12.8 1.3 0.068 12.7 0.9 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Abhydrolase_6 PF12697.2 EMD60699.1 - 1.3e-26 93.8 0.0 2.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60699.1 - 1.5e-14 54.1 0.2 1.8e-12 47.3 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60699.1 - 6.8e-13 48.5 0.0 2.5e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD60699.1 - 0.00091 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PX PF00787.19 EMD60700.1 - 7.4e-14 51.4 0.0 3e-13 49.5 0.0 2.1 1 1 1 2 2 2 1 PX domain SNARE PF05739.14 EMD60700.1 - 2.1e-08 33.7 4.7 4.9e-08 32.5 3.3 1.7 1 0 0 1 1 1 1 SNARE domain Helicase_IV_N PF12462.3 EMD60700.1 - 0.016 14.8 1.7 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal IncA PF04156.9 EMD60700.1 - 2.1 7.8 6.6 7.9 6.0 0.8 2.6 2 1 1 3 3 3 0 IncA protein Aldolase_II PF00596.16 EMD60701.1 - 7.9e-25 87.5 0.0 9.7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 EMD60702.1 - 4e-32 111.1 0.0 7.5e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD60702.1 - 2.6e-09 36.8 13.0 4.7e-09 36.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EMD60703.1 - 1.6e-21 77.2 0.0 2.1e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60703.1 - 3e-12 46.6 0.0 3.8e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60703.1 - 2.2e-07 30.7 0.0 3.7e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD60703.1 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMD60703.1 - 0.0074 15.5 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EMD60703.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 EMD60703.1 - 0.012 14.4 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Lipase_2 PF01674.13 EMD60703.1 - 0.035 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.8 EMD60703.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.11 EMD60704.1 - 2.6e-36 125.0 47.2 1.1e-35 122.9 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EMD60705.1 - 5.5e-33 114.1 0.0 7.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.15 EMD60705.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin central region Mitochondr_Som1 PF11093.3 EMD60706.1 - 0.081 12.7 0.4 0.098 12.4 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Glyco_hydro_61 PF03443.9 EMD60707.1 - 4.9e-50 170.3 0.0 6.5e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMD60707.1 - 8.1e-09 34.9 11.4 2.2e-08 33.5 7.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain HAD PF12710.2 EMD60708.1 - 3.8e-15 56.5 0.0 5.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD60708.1 - 1.4e-09 37.9 0.1 5.7e-08 32.6 0.0 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD60708.1 - 2.8e-09 37.7 0.2 1.6e-07 31.9 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMD60708.1 - 0.0002 21.6 0.0 0.00053 20.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMD60708.1 - 0.00059 19.0 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.7 EMD60708.1 - 0.035 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) UMPH-1 PF05822.7 EMD60708.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) adh_short PF00106.20 EMD60709.1 - 1.7e-18 67.0 0.3 3.3e-17 62.8 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD60709.1 - 8.9e-09 35.2 0.0 6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EMD60709.1 - 5.3e-05 23.0 0.0 0.00063 19.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD60709.1 - 0.00054 19.4 0.1 0.0067 15.8 0.1 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.15 EMD60710.1 - 1.5e-19 70.1 0.0 3.3e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMD60710.1 - 1.5e-07 30.3 0.0 2.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMD60710.1 - 6.4e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PHD PF00628.24 EMD60711.1 - 5.8e-11 41.9 8.6 1.4e-10 40.7 6.0 1.7 1 0 0 1 1 1 1 PHD-finger DUF465 PF04325.8 EMD60711.1 - 0.057 13.1 2.1 0.21 11.3 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Ribosomal_60s PF00428.14 EMD60711.1 - 0.17 12.2 8.7 8 6.9 0.1 3.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein COesterase PF00135.23 EMD60712.1 - 1.3e-59 202.3 0.0 1.7e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD60712.1 - 2.7e-06 27.1 0.1 0.055 13.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 EMD60712.1 - 0.0089 15.4 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 EMD60712.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 EMD60712.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.19 EMD60713.1 - 4.7e-70 236.3 24.3 5.7e-70 236.1 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60713.1 - 8.7e-18 64.1 35.7 1.3e-17 63.5 20.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Arteri_Gl PF00951.13 EMD60713.1 - 0.66 9.5 6.0 0.36 10.3 2.1 2.0 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Fungal_trans PF04082.13 EMD60714.1 - 0.0005 19.0 0.3 0.00077 18.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 EMD60715.1 - 1.1e-45 156.3 0.0 2.5e-45 155.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD60715.1 - 1.5e-08 34.9 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EMD60715.1 - 0.73 9.9 5.8 1.7 8.7 0.6 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_10 PF00331.15 EMD60717.1 - 3.5e-101 338.4 1.4 4.1e-101 338.2 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EMD60717.1 - 5.9e-12 45.0 9.3 5.9e-12 45.0 6.4 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain LysM PF01476.15 EMD60719.1 - 4.7e-28 96.8 4.2 0.00089 19.0 0.0 8.2 8 0 0 8 8 8 6 LysM domain HTH_Tnp_1 PF01527.15 EMD60719.1 - 0.00021 21.1 0.1 16 5.5 0.0 4.2 4 0 0 4 4 4 2 Transposase DUF4348 PF14254.1 EMD60719.1 - 0.00037 19.6 0.0 4.1 6.4 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4348) LRV_FeS PF05484.6 EMD60719.1 - 0.0071 15.8 0.1 10 5.8 0.0 3.6 3 0 0 3 3 3 2 LRV protein FeS4 cluster Glyco_hydro_18 PF00704.23 EMD60720.1 - 9.6e-76 255.4 4.1 1.5e-75 254.7 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD60720.1 - 5.9e-07 29.3 14.8 5.9e-07 29.3 10.3 4.2 3 0 0 3 3 3 1 Chitin recognition protein DUF1056 PF06341.6 EMD60722.1 - 3.2 7.8 6.5 0.66 10.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Abhydrolase_6 PF12697.2 EMD60723.1 - 4.8e-07 29.8 0.0 2.9e-05 24.0 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD60723.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EMD60723.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 EMD60723.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TPP_enzyme_N PF02776.13 EMD60724.1 - 4.6e-05 22.9 0.0 4.9e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_M10 PF00413.19 EMD60725.1 - 0.06 13.0 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.2 EMD60725.1 - 0.091 11.6 0.2 0.17 10.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) PCI PF01399.22 EMD60728.1 - 0.19 12.0 1.6 0.42 10.9 1.1 1.7 1 1 0 1 1 1 0 PCI domain Ank PF00023.25 EMD60731.1 - 7.9e-24 82.2 0.8 4.3e-08 32.5 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMD60731.1 - 2.3e-20 72.7 0.2 3.4e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD60731.1 - 2.3e-19 69.3 0.5 2.3e-11 43.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD60731.1 - 2.4e-14 52.0 0.3 0.0019 18.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMD60731.1 - 4.6e-09 36.2 0.5 4e-07 30.0 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) UBA PF00627.26 EMD60731.1 - 0.0046 16.7 0.0 27 4.7 0.0 3.5 4 0 0 4 4 4 0 UBA/TS-N domain DUF4142 PF13628.1 EMD60731.1 - 0.035 14.1 0.0 6.7 6.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4142) Ank_2 PF12796.2 EMD60732.1 - 3.2e-18 65.8 0.5 1.3e-17 63.8 0.2 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD60732.1 - 9.3e-18 63.0 0.6 3.6e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD60732.1 - 4.8e-11 41.7 0.4 3.7e-05 23.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD60732.1 - 5.5e-11 42.6 1.4 1.4e-05 25.4 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD60732.1 - 1.5e-09 37.8 0.2 1.1e-06 28.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) ABC2_membrane_3 PF12698.2 EMD60734.1 - 0.0012 17.9 5.4 0.0016 17.5 3.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Virul_fac_BrkB PF03631.10 EMD60734.1 - 0.0035 16.7 12.0 0.0044 16.4 8.3 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF2976 PF11190.3 EMD60734.1 - 0.23 11.0 5.5 0.45 10.0 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2976) DUF2516 PF10724.4 EMD60734.1 - 0.27 11.2 9.4 1.4 8.9 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) UPF0182 PF03699.8 EMD60734.1 - 2.8 5.7 4.6 3.3 5.5 3.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FA_desaturase PF00487.19 EMD60734.1 - 5.3 6.3 12.6 25 4.1 0.2 2.0 1 1 1 2 2 2 0 Fatty acid desaturase DUF2975 PF11188.3 EMD60734.1 - 6.5 6.4 16.1 0.72 9.5 3.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) CBM_4_9 PF02018.12 EMD60735.1 - 0.02 14.9 0.2 0.028 14.4 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain PilS PF08805.6 EMD60735.1 - 0.063 12.7 0.4 0.12 11.9 0.2 1.5 1 1 0 1 1 1 0 PilS N terminal EHN PF06441.7 EMD60736.1 - 1.1e-26 92.9 0.1 1.9e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMD60736.1 - 2.2e-15 57.1 0.2 5.9e-15 55.7 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60736.1 - 5.4e-05 22.8 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60736.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Glyco_hydro_43 PF04616.9 EMD60737.1 - 4.8e-65 219.4 5.7 6e-65 219.1 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Reg_prop PF07494.6 EMD60737.1 - 0.055 13.5 0.4 3.6 7.9 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller FAD_binding_4 PF01565.18 EMD60740.1 - 0.00034 20.1 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 EMD60740.1 - 0.00047 19.8 3.3 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase His_Phos_1 PF00300.17 EMD60741.1 - 9.6e-07 29.0 0.0 9.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DnaJ PF00226.26 EMD60742.1 - 1.4e-21 75.9 0.9 4.7e-21 74.2 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain Cauli_DNA-bind PF03310.8 EMD60742.1 - 0.0035 17.1 1.4 0.0035 17.1 1.0 2.4 2 0 0 2 2 2 1 Caulimovirus DNA-binding protein zinc-ribbons_6 PF07191.7 EMD60742.1 - 0.35 10.7 6.4 1.4 8.7 1.1 2.6 1 1 1 2 2 2 0 zinc-ribbons MRFAP1 PF15155.1 EMD60744.1 - 0.0059 16.9 3.2 0.0094 16.2 2.2 1.3 1 0 0 1 1 1 1 MORF4 family-associated protein1 ApoL PF05461.6 EMD60744.1 - 0.018 14.2 4.3 0.024 13.9 3.0 1.1 1 0 0 1 1 1 0 Apolipoprotein L V_ATPase_I PF01496.14 EMD60744.1 - 0.061 11.1 0.2 0.068 11.0 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HisKA_3 PF07730.8 EMD60744.1 - 2.4 8.5 6.0 17 5.8 0.3 3.2 3 1 1 4 4 4 0 Histidine kinase TMEM238 PF15125.1 EMD60746.1 - 0.098 12.5 1.0 0.14 12.1 0.7 1.3 1 0 0 1 1 1 0 TMEM238 protein family Exo_endo_phos_2 PF14529.1 EMD60747.1 - 3.3e-07 29.9 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMD60747.1 - 0.031 14.1 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1132 PF06575.7 EMD60747.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Katanin_con80 PF13925.1 EMD60748.1 - 0.045 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 con80 domain of Katanin eIF3g PF12353.3 EMD60748.1 - 0.093 12.6 14.0 0.1 12.5 0.5 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HisKA_3 PF07730.8 EMD60748.1 - 1.7 9.0 5.7 2.1 8.7 0.6 3.0 1 1 1 2 2 2 0 Histidine kinase DDE_1 PF03184.14 EMD60749.1 - 1.7e-34 118.8 0.0 2.4e-32 111.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD60749.1 - 3e-06 27.0 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EMD60751.1 - 6.2e-17 61.4 0.0 8.1e-11 41.4 0.1 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease FPN1 PF06963.7 EMD60751.1 - 0.062 11.6 0.0 0.11 10.8 0.0 1.4 1 1 0 1 1 1 0 Ferroportin1 (FPN1) DDE_1 PF03184.14 EMD60752.1 - 0.076 12.1 0.0 0.078 12.1 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3641 PF12345.3 EMD60752.1 - 0.15 11.8 0.2 0.18 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) PDH PF02153.12 EMD60754.1 - 1.3e-13 50.4 0.0 1.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Ribosomal_S11 PF00411.14 EMD60755.1 - 5.1e-41 139.2 0.5 6.2e-41 139.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EMD60755.1 - 0.037 12.9 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Metallophos PF00149.23 EMD60756.1 - 4.3e-12 45.8 1.3 9.7e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD60756.1 - 1.9e-07 31.0 0.1 4.2e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 EMD60757.1 - 2.1e-37 128.5 0.0 3.2e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD60757.1 - 3.5e-11 43.0 0.0 7.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMD60757.1 - 8.5e-05 22.2 1.4 0.017 14.7 0.6 2.9 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Cyclin PF08613.6 EMD60759.1 - 1.4e-11 44.9 1.0 4.3e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EMD60759.1 - 0.046 13.2 0.1 0.073 12.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L30_N PF08079.7 EMD60761.1 - 5.3e-24 84.0 19.2 1.3e-23 82.7 13.3 1.7 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMD60761.1 - 9.7e-21 73.1 2.0 2.3e-20 71.9 1.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Endonuc_BglI PF14562.1 EMD60761.1 - 0.059 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglI adh_short PF00106.20 EMD60764.1 - 2e-16 60.3 0.1 5e-16 59.0 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD60764.1 - 1.6e-06 27.9 0.1 1.6e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMD60764.1 - 0.0072 16.1 0.0 0.01 15.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GYD PF08734.6 EMD60764.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 GYD domain Epimerase PF01370.16 EMD60764.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Actin PF00022.14 EMD60765.1 - 2.1e-53 181.1 0.0 2.1e-28 98.8 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3040 PF11239.3 EMD60765.1 - 0.026 14.5 0.2 0.067 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DASH_Dad4 PF08650.5 EMD60766.1 - 1.4e-28 98.5 5.4 1.6e-28 98.4 3.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Biotin_carb_C PF02785.14 EMD60766.1 - 0.013 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DASH_Dad1 PF08649.5 EMD60766.1 - 0.016 14.9 3.2 0.02 14.6 2.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 Pecanex_C PF05041.10 EMD60766.1 - 0.019 14.0 0.6 0.021 13.8 0.4 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) GM_CSF PF01109.12 EMD60766.1 - 0.036 14.0 0.4 0.041 13.8 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor HOK_GEF PF01848.11 EMD60766.1 - 0.079 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Hok/gef family CD34_antigen PF06365.7 EMD60766.1 - 0.1 12.2 0.8 0.11 12.1 0.5 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family YL1_C PF08265.6 EMD60767.1 - 3.3e-17 61.7 0.2 5.2e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 EMD60768.1 - 1.5e-17 63.7 16.1 1.8e-17 63.5 11.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Dicistro_VP4 PF11492.3 EMD60768.1 - 0.019 14.9 0.1 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 YrhK PF14145.1 EMD60768.1 - 0.036 13.7 2.8 0.036 13.7 1.9 2.2 1 1 1 2 2 2 0 YrhK-like protein SMC_Nse1 PF07574.8 EMD60769.1 - 4.4e-33 114.5 0.0 5.7e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EMD60769.1 - 1.5e-11 44.0 9.7 2.6e-11 43.3 6.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.1 EMD60769.1 - 0.0067 16.4 1.4 0.013 15.4 1.0 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMD60769.1 - 0.1 12.7 6.1 0.3 11.2 4.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Bacteriocin_II PF01721.13 EMD60769.1 - 0.21 11.1 2.1 0.42 10.1 1.5 1.5 1 0 0 1 1 1 0 Class II bacteriocin FANCL_C PF11793.3 EMD60769.1 - 0.24 11.3 4.0 0.6 10.1 2.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 EMD60769.1 - 1 9.2 6.1 1.8 8.4 4.2 1.4 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.17 EMD60769.1 - 1.1 9.0 8.4 0.09 12.5 1.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAHP_synth_1 PF00793.15 EMD60770.1 - 2.8e-99 331.2 0.0 3.4e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Herpes_LMP2 PF07415.6 EMD60771.1 - 0.42 9.1 1.5 0.71 8.4 1.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Y_phosphatase PF00102.22 EMD60772.1 - 6e-62 209.0 1.4 2.4e-32 112.1 0.1 2.7 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 EMD60772.1 - 2.7e-11 43.8 0.0 3.1e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.15 EMD60772.1 - 0.01 15.3 0.1 0.025 14.1 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMD60772.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipase_3 PF01764.20 EMD60773.1 - 9.7e-05 21.9 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) VPS9 PF02204.13 EMD60774.1 - 8.2e-24 83.6 0.0 2.1e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Kinetocho_Slk19 PF12709.2 EMD60775.1 - 4.9e-11 42.5 5.9 4.9e-11 42.5 4.1 4.4 4 0 0 4 4 4 2 Central kinetochore-associated Tropomyosin_1 PF12718.2 EMD60775.1 - 1.5e-05 24.8 17.7 1.5e-05 24.8 12.3 3.3 2 1 0 2 2 2 1 Tropomyosin like Myosin_tail_1 PF01576.14 EMD60775.1 - 0.041 11.6 50.6 1.5 6.4 35.1 3.0 1 1 0 1 1 1 0 Myosin tail Baculo_PEP_C PF04513.7 EMD60775.1 - 0.097 12.4 2.7 3.1 7.6 0.0 3.4 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EMD60775.1 - 0.2 11.7 14.0 5.5 7.1 2.0 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EMD60775.1 - 0.46 9.6 9.2 1.5 7.9 2.6 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EMD60775.1 - 4.7 7.1 9.9 8.9 6.3 0.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.1 EMD60775.1 - 5.5 5.8 44.6 0.085 11.8 7.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 EMD60775.1 - 9.3 6.1 43.2 0.28 11.0 1.0 5.1 4 2 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4558 PF15104.1 EMD60778.1 - 0.28 11.1 4.0 0.11 12.4 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) CFEM PF05730.6 EMD60779.1 - 2e-13 49.9 11.6 3e-13 49.3 8.0 1.3 1 0 0 1 1 1 1 CFEM domain GCIP PF13324.1 EMD60780.1 - 3.6e-10 39.5 4.0 7.3e-10 38.5 2.8 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EMD60780.1 - 0.04 13.5 2.0 0.064 12.8 1.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PRKCSH-like PF12999.2 EMD60781.1 - 5.5e-43 146.5 2.4 1.1e-23 83.7 0.3 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EMD60781.1 - 2.2e-33 114.9 0.8 4.5e-32 110.6 0.1 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EMD60781.1 - 3.7e-11 43.6 0.3 1.1e-10 42.1 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein GOLGA2L5 PF15070.1 EMD60781.1 - 0.042 12.3 0.1 0.042 12.3 0.1 2.3 3 0 0 3 3 3 0 Putative golgin subfamily A member 2-like protein 5 ESAG1 PF03238.8 EMD60781.1 - 0.044 13.0 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 ESAG protein Isy1 PF06246.7 EMD60781.1 - 0.083 12.2 5.1 0.055 12.8 2.1 1.9 1 1 1 2 2 2 0 Isy1-like splicing family Lectin_N PF03954.9 EMD60781.1 - 0.089 12.1 1.3 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DivIC PF04977.10 EMD60781.1 - 0.1 12.1 0.2 0.1 12.1 0.1 4.0 3 1 0 3 3 3 0 Septum formation initiator Herpes_UL6 PF01763.11 EMD60781.1 - 0.13 10.3 0.5 0.25 9.4 0.3 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.5 EMD60781.1 - 0.17 11.9 1.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HR1 PF02185.11 EMD60781.1 - 0.27 11.0 7.6 1.2 8.8 0.7 3.0 3 0 0 3 3 3 0 Hr1 repeat TPR_MLP1_2 PF07926.7 EMD60781.1 - 0.32 10.7 10.3 0.12 12.1 1.1 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 EMD60781.1 - 0.38 10.6 5.1 1.4 8.7 0.6 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF2031 PF09592.5 EMD60781.1 - 0.46 9.6 2.3 0.33 10.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Filament PF00038.16 EMD60781.1 - 0.79 9.1 11.0 2.1 7.7 0.3 2.9 2 1 0 3 3 3 0 Intermediate filament protein DUF4407 PF14362.1 EMD60781.1 - 0.83 8.5 11.5 7.1 5.4 5.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.6 EMD60781.1 - 1.4 8.2 4.1 6.2 6.1 0.1 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin_2 PF01920.15 EMD60781.1 - 3.3 7.5 9.8 23 4.8 1.6 3.2 2 1 1 3 3 3 0 Prefoldin subunit IncA PF04156.9 EMD60781.1 - 6 6.4 14.3 37 3.8 0.2 3.2 2 1 0 2 2 2 0 IncA protein Phytase-like PF13449.1 EMD60782.1 - 1.1e-28 100.5 0.3 2.3e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 Esterase-like activity of phytase DUF3328 PF11807.3 EMD60784.1 - 1.7e-27 96.5 0.1 2.3e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.17 EMD60785.1 - 3.6e-65 220.3 0.0 4.6e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3114 PF11311.3 EMD60785.1 - 0.013 14.8 0.1 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Brr6_like_C_C PF10104.4 EMD60786.1 - 3.3e-41 139.9 0.7 5.4e-41 139.2 0.5 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Shisa PF13908.1 EMD60786.1 - 1.1 9.4 9.5 0.051 13.7 2.2 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Acyl_transf_1 PF00698.16 EMD60787.1 - 1.9e-79 267.3 0.0 6.9e-78 262.1 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMD60787.1 - 2.6e-37 126.9 0.0 5.3e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMD60787.1 - 4.6e-32 109.5 0.6 3.1e-31 106.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMD60787.1 - 2.2e-23 82.5 0.0 1.1e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EMD60787.1 - 0.002 17.3 0.5 0.14 11.3 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase adh_short_C2 PF13561.1 EMD60788.1 - 1e-19 71.2 0.0 1.8e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EMD60788.1 - 1.2e-19 70.8 0.0 2.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EMD60788.1 - 5.8e-18 64.7 0.0 1.3e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EMD60788.1 - 2.1e-10 40.4 0.0 5.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMD60788.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD60788.1 - 0.032 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 KR domain Astacin PF01400.19 EMD60789.1 - 7.9e-12 44.9 0.3 1.1e-08 34.6 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 EMD60789.1 - 0.037 13.7 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.1 EMD60789.1 - 0.069 13.0 0.7 0.099 12.5 0.5 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.6 EMD60789.1 - 0.087 12.5 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 Git3 PF11710.3 EMD60791.1 - 1.3e-20 73.8 10.2 2.5e-20 72.9 7.1 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EMD60791.1 - 1.4e-12 47.2 0.8 2.2e-12 46.6 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EMD60791.1 - 3e-09 36.2 11.6 2.3e-06 26.7 7.1 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor DUF4234 PF14018.1 EMD60791.1 - 0.0022 17.7 0.1 0.0091 15.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) Epimerase PF01370.16 EMD60791.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Git3_C PF11970.3 EMD60791.1 - 0.045 13.5 4.5 0.055 13.2 0.0 3.0 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1003 PF06210.6 EMD60792.1 - 0.031 14.1 0.7 0.053 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Methyltransf_2 PF00891.13 EMD60793.1 - 5.1e-12 45.5 0.7 7e-08 31.9 0.1 2.9 2 1 0 2 2 2 2 O-methyltransferase Methyltransf_20 PF12147.3 EMD60793.1 - 0.11 11.3 0.4 0.55 9.0 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase zf-RING_2 PF13639.1 EMD60794.1 - 2.8e-14 52.6 4.5 4.4e-14 52.0 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD60794.1 - 8.4e-08 32.2 0.7 1.5e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD60794.1 - 2.8e-07 30.0 3.7 4.6e-07 29.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD60794.1 - 1.9e-06 27.7 4.8 3.1e-06 27.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD60794.1 - 3.8e-06 26.5 2.6 6e-06 25.8 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD60794.1 - 3.5e-05 23.3 1.4 5.7e-05 22.7 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD60794.1 - 0.0027 17.4 0.4 0.0057 16.4 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMD60794.1 - 0.0034 16.9 2.7 0.0063 16.0 1.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMD60794.1 - 0.086 12.8 2.6 0.14 12.1 1.8 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EMD60794.1 - 0.22 11.2 3.1 0.4 10.4 2.1 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EMD60794.1 - 2.7 8.0 4.4 16 5.5 3.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Na_Ca_ex PF01699.19 EMD60795.1 - 1.2e-31 109.1 21.4 1.2e-17 63.7 5.8 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EMD60795.1 - 8.9e-14 51.6 7.2 8.9e-14 51.6 5.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF307) DUF4094 PF13334.1 EMD60795.1 - 0.34 11.3 4.1 0.85 10.0 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) AAA PF00004.24 EMD60796.1 - 6.7e-44 149.2 0.0 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EMD60796.1 - 8.5e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMD60796.1 - 1.7e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD60796.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD60796.1 - 3.4e-06 27.2 0.1 0.00017 21.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD60796.1 - 4.6e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMD60796.1 - 8.7e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMD60796.1 - 8.9e-05 23.3 0.0 0.00019 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMD60796.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMD60796.1 - 0.001 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EMD60796.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMD60796.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD60796.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EMD60796.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMD60796.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EMD60796.1 - 0.0067 15.6 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EMD60796.1 - 0.0072 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EMD60796.1 - 0.013 15.7 0.0 0.046 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EMD60796.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EMD60796.1 - 0.016 14.5 0.1 0.078 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMD60796.1 - 0.017 14.6 0.0 0.082 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EMD60796.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMD60796.1 - 0.023 14.3 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD60796.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EMD60796.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EMD60796.1 - 0.07 12.7 0.0 0.35 10.5 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EMD60796.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Histone PF00125.19 EMD60796.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NB-ARC PF00931.17 EMD60796.1 - 0.093 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EMD60796.1 - 0.098 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DivIC PF04977.10 EMD60796.1 - 0.66 9.4 3.0 0.5 9.8 0.8 1.7 2 0 0 2 2 1 0 Septum formation initiator MFS_1 PF07690.11 EMD60797.1 - 5.1e-22 78.0 29.6 1.3e-14 53.7 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD60797.1 - 5.9e-13 48.2 24.4 8.1e-12 44.4 16.9 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 EMD60797.1 - 0.02 15.0 0.1 0.089 12.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) adh_short PF00106.20 EMD60798.1 - 1.2e-30 106.5 0.8 1.7e-30 106.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD60798.1 - 2.3e-14 53.7 0.0 2.7e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD60798.1 - 6.4e-14 52.0 0.3 9.7e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD60798.1 - 1.1e-07 31.9 0.1 1.9e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD60798.1 - 0.0051 15.7 0.0 0.0086 15.0 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMD60798.1 - 0.0089 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMD60798.1 - 0.021 14.8 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 EMD60798.1 - 0.042 13.9 0.1 0.09 12.8 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMD60798.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EMD60798.1 - 0.15 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family PFK PF00365.15 EMD60799.1 - 1.2e-161 536.2 6.6 1.9e-122 407.6 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase Nic96 PF04097.9 EMD60800.1 - 1.2e-197 657.8 0.0 1.7e-197 657.3 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Med27 PF11571.3 EMD60802.1 - 5.1e-17 61.7 0.5 9.8e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 FMN_dh PF01070.13 EMD60803.1 - 1.1e-120 402.7 0.2 1.4e-120 402.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMD60803.1 - 4.1e-23 80.9 0.0 8e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMD60803.1 - 5.6e-08 32.0 0.2 1.2e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMD60803.1 - 0.00065 18.6 0.8 0.0011 17.8 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMD60803.1 - 0.0044 16.2 0.4 0.0068 15.5 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EMD60803.1 - 0.0096 15.2 1.3 0.4 9.8 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EMD60803.1 - 0.032 13.3 0.2 6.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.17 EMD60804.1 - 6.5e-41 139.4 0.0 4.2e-38 130.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMD60804.1 - 2.2e-18 66.8 0.0 3.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD60804.1 - 2e-12 46.6 0.0 3.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD60804.1 - 0.00029 20.0 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD60804.1 - 0.00048 20.0 0.0 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMD60804.1 - 0.0016 18.4 0.0 0.027 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EMD60804.1 - 0.0069 15.8 0.2 0.43 10.0 0.0 2.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EMD60804.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMD60804.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMD60804.1 - 0.05 12.8 0.1 0.092 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EMD60804.1 - 0.061 12.8 0.2 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMD60804.1 - 0.11 12.4 0.8 0.79 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMD60804.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EMD60804.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidohydro_4 PF13147.1 EMD60805.1 - 6.1e-14 52.7 0.1 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EMD60805.1 - 1.2e-10 41.5 0.0 1.6e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMD60805.1 - 7.3e-09 35.3 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD60805.1 - 5.1e-05 23.0 0.0 0.00016 21.3 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_3 PF00933.16 EMD60806.1 - 4.1e-55 186.8 0.0 5.6e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD60806.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EMD60806.1 - 3.1e-05 23.9 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD60806.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MSA-2c PF12238.3 EMD60806.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c NDT80_PhoG PF05224.7 EMD60807.1 - 1.8e-35 122.5 0.0 3.7e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.11 EMD60808.1 - 1.7e-40 138.7 0.0 2.6e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMD60808.1 - 1.7e-35 122.2 0.0 2.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 EMD60809.1 - 6.8e-13 48.0 33.3 1.1e-12 47.3 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD60809.1 - 6.7e-08 32.1 9.4 6.7e-08 32.1 6.5 3.2 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 Glucosamine_iso PF01182.15 EMD60810.1 - 3.8e-24 85.5 0.0 6.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NCA2 PF08637.5 EMD60811.1 - 9.4e-85 284.0 0.7 1.5e-84 283.2 0.5 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EMD60811.1 - 0.076 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Ras PF00071.17 EMD60812.1 - 1.6e-64 216.1 0.0 2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD60812.1 - 6.2e-19 68.6 0.0 8.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD60812.1 - 5.1e-13 48.6 0.0 6.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD60812.1 - 2.5e-06 27.0 0.0 5.2e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD60812.1 - 8.4e-06 25.0 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD60812.1 - 0.0055 16.6 0.0 0.009 15.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMD60812.1 - 0.014 14.6 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMD60812.1 - 0.043 13.1 0.0 0.19 10.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EMD60812.1 - 0.053 13.7 0.0 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMD60812.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EMD60812.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMD60812.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.22 EMD60813.1 - 9e-52 175.8 0.0 2.2e-51 174.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EMD60813.1 - 1.7e-39 135.8 1.9 3.4e-39 134.8 1.3 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EMD60813.1 - 2.6e-23 82.0 0.0 2.4e-22 78.9 0.0 2.8 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EMD60813.1 - 9.5e-14 50.5 0.0 3e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 EMD60813.1 - 0.00037 20.7 0.1 0.0045 17.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD60813.1 - 0.021 14.4 4.0 0.046 13.3 0.2 3.3 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.1 EMD60813.1 - 0.049 14.3 2.8 0.26 12.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD60813.1 - 0.14 12.9 8.4 1.2 9.9 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat COX16 PF14138.1 EMD60814.1 - 1e-31 108.9 0.3 1.3e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 7tm_7 PF08395.7 EMD60814.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Synaptobrevin PF00957.16 EMD60815.1 - 0.02 14.4 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin HMG_CoA_synt_C PF08540.5 EMD60816.1 - 7.9e-102 340.5 0.3 1e-101 340.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EMD60816.1 - 2.9e-95 316.7 0.1 4.2e-95 316.2 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal MaoC_dehydratas PF01575.14 EMD60817.1 - 2.5e-22 78.5 0.0 5.1e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EMD60817.1 - 3.5e-11 43.0 0.0 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Pkinase PF00069.20 EMD60818.1 - 4.7e-70 235.7 0.0 6.5e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60818.1 - 1.8e-30 105.8 0.0 2.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMD60818.1 - 2.5e-12 47.1 1.1 1.1e-11 45.0 0.1 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMD60818.1 - 8.4e-09 34.7 0.1 1.6e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD60818.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMD60818.1 - 0.068 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EMD60818.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CBFD_NFYB_HMF PF00808.18 EMD60819.1 - 1.1e-17 63.8 0.8 2e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD60819.1 - 0.00059 19.9 0.0 0.00097 19.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Snf7 PF03357.16 EMD60820.1 - 1.3e-13 50.6 11.9 1.7e-13 50.3 8.2 1.2 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 EMD60820.1 - 0.41 10.4 3.1 0.7 9.7 1.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.6 EMD60820.1 - 1.3 9.4 8.1 0.43 11.0 2.0 2.3 2 0 0 2 2 2 0 Cytochrome b562 DUF3669 PF12417.3 EMD60821.1 - 4.6e-22 77.5 0.1 1e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Ribosomal_S21e PF01249.13 EMD60822.1 - 3.1e-36 123.1 0.0 3.4e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Sugar_tr PF00083.19 EMD60824.1 - 2.1e-68 230.9 24.1 2.4e-68 230.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60824.1 - 1.2e-13 50.5 32.0 2.2e-13 49.6 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD60824.1 - 4.1e-05 22.1 4.0 4.1e-05 22.1 2.8 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Peptidase_M28 PF04389.12 EMD60826.1 - 9.8e-32 110.1 0.3 2.2e-31 108.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EMD60826.1 - 2.9e-17 62.1 0.1 5.8e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 PA domain TFIIB PF00382.14 EMD60827.1 - 6.4e-31 105.9 1.2 6.4e-18 64.3 0.1 3.0 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EMD60827.1 - 2.6e-21 75.6 1.5 2.6e-21 75.6 1.0 2.9 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Rtf2 PF04641.7 EMD60827.1 - 0.015 14.5 0.3 0.015 14.5 0.2 2.3 3 0 0 3 3 3 0 Rtf2 RING-finger Cyclin_N PF00134.18 EMD60827.1 - 0.031 13.8 0.1 0.56 9.7 0.0 2.4 1 1 1 2 2 2 0 Cyclin, N-terminal domain Methyltransf_31 PF13847.1 EMD60828.1 - 4.2e-12 45.9 0.1 6.2e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD60828.1 - 4.3e-11 42.4 0.0 9.2e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EMD60828.1 - 6.1e-09 36.4 0.0 1.6e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD60828.1 - 2.5e-08 33.9 0.0 7.1e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EMD60828.1 - 1.2e-07 31.0 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EMD60828.1 - 1.8e-07 31.5 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMD60828.1 - 3.5e-06 25.9 0.1 5.3e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EMD60828.1 - 2.7e-05 23.5 0.1 5.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMD60828.1 - 5.3e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD60828.1 - 9.7e-05 22.6 0.0 0.0003 21.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD60828.1 - 0.00015 20.9 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EMD60828.1 - 0.0015 18.9 0.1 0.0038 17.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMD60828.1 - 0.016 16.0 0.0 0.03 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMD60828.1 - 0.028 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EMD60828.1 - 0.074 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EMD60828.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Allexi_40kDa PF05549.6 EMD60829.1 - 0.15 11.3 0.7 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein Lum_binding PF00677.12 EMD60830.1 - 7.8e-40 134.6 0.3 1.2e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain HlyD_3 PF13437.1 EMD60830.1 - 0.079 13.3 0.1 0.71 10.2 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Kinesin PF00225.18 EMD60831.1 - 6.9e-60 202.5 0.2 1.2e-59 201.7 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain CoA_transf_3 PF02515.12 EMD60831.1 - 5.8e-54 182.2 0.7 1.5e-53 180.8 0.0 2.0 2 0 0 2 2 2 1 CoA-transferase family III bZIP_1 PF00170.16 EMD60831.1 - 0.27 11.2 7.0 0.048 13.6 1.0 2.6 3 0 0 3 3 3 0 bZIP transcription factor AAA_33 PF13671.1 EMD60831.1 - 5.6 6.8 9.1 0.53 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain PHD PF00628.24 EMD60832.1 - 2.1e-09 36.9 7.2 3.4e-09 36.2 5.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EMD60832.1 - 0.00012 21.4 2.2 0.00012 21.4 1.5 1.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EMD60832.1 - 0.00065 19.3 5.0 0.0012 18.5 3.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EMD60832.1 - 0.001 18.7 2.0 0.0019 17.8 1.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EMD60832.1 - 0.0043 16.3 4.8 0.016 14.5 3.3 2.0 1 1 0 1 1 1 1 PHD-finger PSCyt3 PF07627.6 EMD60832.1 - 0.0061 16.4 3.8 0.51 10.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1588) FYVE_2 PF02318.11 EMD60832.1 - 0.12 12.2 3.1 0.2 11.5 2.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FCP1_C PF09309.5 EMD60832.1 - 0.22 10.8 11.9 2.1 7.5 4.1 2.3 2 0 0 2 2 2 0 FCP1, C-terminal zf-CHY PF05495.7 EMD60832.1 - 1 9.5 7.8 0.63 10.2 1.2 2.3 1 1 1 2 2 2 0 CHY zinc finger PAT1 PF09770.4 EMD60832.1 - 7.2 4.7 18.4 0.77 7.9 9.7 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RTA1 PF04479.8 EMD60833.1 - 6.3e-45 153.4 2.7 8.8e-45 152.9 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein COesterase PF00135.23 EMD60834.1 - 4.8e-105 352.2 0.0 6.1e-105 351.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD60834.1 - 2.9e-06 27.0 0.2 4e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMD60834.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMD60834.1 - 0.0012 18.0 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aa_trans PF01490.13 EMD60835.1 - 1.8e-34 118.9 42.5 2.1e-34 118.7 29.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMD60835.1 - 0.3 9.5 57.6 98 1.2 39.9 2.2 1 1 0 1 1 1 0 Amino acid permease MFS_1 PF07690.11 EMD60836.1 - 8.8e-34 116.7 26.7 1.1e-28 99.9 4.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD60836.1 - 4.6e-07 28.7 3.8 4.6e-07 28.7 2.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMD60836.1 - 0.0021 16.3 0.4 0.0031 15.7 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CFEM PF05730.6 EMD60837.1 - 1.1e-09 37.9 4.6 4.4e-09 36.0 3.2 2.1 1 0 0 1 1 1 1 CFEM domain CRAL_TRIO PF00650.15 EMD60839.1 - 7.7e-11 41.7 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD60839.1 - 2.2e-05 24.4 0.2 2.2e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain SAPS PF04499.10 EMD60839.1 - 0.023 13.3 1.5 0.026 13.2 1.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3824 PF12868.2 EMD60839.1 - 0.26 12.2 11.1 0.45 11.4 7.7 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3439 PF11921.3 EMD60839.1 - 0.35 10.6 4.0 0.71 9.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EMD60839.1 - 1.4 6.6 6.5 1.8 6.2 4.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4045 PF13254.1 EMD60839.1 - 2.3 7.3 21.1 4.2 6.5 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 EMD60839.1 - 2.9 5.5 10.3 3.6 5.1 7.1 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 EMD60839.1 - 3.4 5.8 15.7 5.1 5.2 10.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TP53IP5 PF15331.1 EMD60839.1 - 6.5 6.5 14.1 12 5.6 8.4 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 SDA1 PF05285.7 EMD60839.1 - 9.2 5.4 21.9 14 4.8 15.2 1.2 1 0 0 1 1 1 0 SDA1 RRM_5 PF13893.1 EMD60840.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD60840.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EMD60840.1 - 0.015 15.3 0.2 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding FGGY_C PF02782.11 EMD60841.1 - 5.2e-50 169.8 0.2 8.6e-50 169.1 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMD60841.1 - 3.2e-26 92.1 0.5 1.8e-24 86.4 0.3 2.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EMD60841.1 - 0.00051 19.4 0.1 0.0026 17.0 0.0 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF918 PF06033.6 EMD60841.1 - 0.12 11.9 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) dCMP_cyt_deam_1 PF00383.17 EMD60843.1 - 1.2e-23 82.7 0.1 1.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMD60843.1 - 0.0016 18.2 0.4 0.027 14.3 0.1 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase Cg6151-P PF10233.4 EMD60844.1 - 1.3e-42 144.3 15.9 1.6e-42 144.0 11.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P YhfT PF10797.4 EMD60844.1 - 0.0015 17.4 4.5 0.0018 17.1 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function T_cell_tran_alt PF15128.1 EMD60844.1 - 0.093 12.1 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Cytochrom_B558a PF05038.8 EMD60844.1 - 0.17 11.5 0.2 0.17 11.5 0.1 2.3 2 1 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF3784 PF12650.2 EMD60844.1 - 6 6.8 13.6 1.9 8.4 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4149 PF13664.1 EMD60844.1 - 9.1 6.4 11.4 0.65 10.0 2.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3210 PF11489.3 EMD60845.1 - 4e-205 683.6 61.6 4e-205 683.6 42.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) TPR_12 PF13424.1 EMD60846.1 - 5.9e-31 106.2 9.2 6.9e-11 41.9 0.1 4.8 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 EMD60846.1 - 4.5e-30 102.6 1.6 7e-07 28.9 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat NB-ARC PF00931.17 EMD60846.1 - 1.9e-12 46.6 0.1 3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 EMD60846.1 - 3.4e-11 43.1 0.1 5e-07 29.7 0.0 3.3 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMD60846.1 - 2e-08 34.4 6.7 0.014 15.7 0.2 5.1 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD60846.1 - 1.7e-07 30.6 1.8 0.14 12.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD60846.1 - 3.7e-07 29.6 3.4 0.0013 18.3 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_6 PF13174.1 EMD60846.1 - 6e-07 29.4 0.8 0.061 13.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD60846.1 - 1.2e-06 29.0 0.7 0.004 17.7 0.1 4.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD60846.1 - 3.5e-05 24.0 3.9 0.28 11.9 0.1 5.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD60846.1 - 0.00029 20.3 1.8 24 5.0 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 EMD60846.1 - 0.00038 20.5 0.2 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD60846.1 - 0.00041 20.3 0.2 0.00041 20.3 0.1 2.9 3 1 0 3 3 2 1 AAA ATPase domain SPO22 PF08631.5 EMD60846.1 - 0.00094 18.3 0.4 0.013 14.5 0.0 2.6 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.1 EMD60846.1 - 0.0015 18.5 0.1 0.9 9.9 0.0 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMD60846.1 - 0.0031 17.7 9.3 0.2 12.2 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EMD60846.1 - 0.0043 17.1 9.1 1.9 8.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD60846.1 - 0.0068 16.1 0.4 3.6 7.5 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD60846.1 - 0.017 14.6 5.8 6.5 6.5 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_25 PF13481.1 EMD60846.1 - 0.032 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD60846.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase FAD_binding_4 PF01565.18 EMD60847.1 - 1.9e-23 82.4 0.6 4.1e-23 81.3 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD60847.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Polysacc_deac_1 PF01522.16 EMD60849.1 - 2.4e-28 98.2 0.0 4.2e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMD60849.1 - 1.2e-14 53.9 82.2 1.1e-05 25.3 12.9 4.0 3 1 1 4 4 4 3 Chitin recognition protein Pkinase PF00069.20 EMD60850.1 - 1.1e-64 218.1 0.0 1.5e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60850.1 - 1.9e-29 102.5 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60850.1 - 0.038 12.9 0.0 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_C PF00433.19 EMD60850.1 - 0.22 12.0 2.8 0.7 10.4 2.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain RRM_1 PF00076.17 EMD60851.1 - 6e-10 38.6 0.0 1.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60851.1 - 4.7e-08 32.8 0.0 9.6e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD60851.1 - 0.027 14.2 0.3 0.027 14.2 0.2 2.3 2 2 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 EMD60851.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADH_zinc_N PF00107.21 EMD60852.1 - 1.3e-12 47.3 0.0 2.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD60852.1 - 0.0025 17.5 0.0 0.0099 15.6 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MRJP PF03022.11 EMD60853.1 - 3.4e-33 115.1 0.0 6.5e-33 114.1 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EMD60853.1 - 0.011 15.1 0.0 0.055 12.8 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Med17 PF10156.4 EMD60854.1 - 4.7e-88 295.5 1.5 6.3e-88 295.0 1.1 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EMD60855.1 - 9.9e-187 620.6 0.0 1.1e-186 620.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase NADH-u_ox-rdase PF10785.4 EMD60856.1 - 0.051 13.8 1.2 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit KAR9 PF08580.5 EMD60857.1 - 5.9 5.0 14.1 6.9 4.7 9.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WD40 PF00400.27 EMD60859.1 - 1.7e-08 34.0 0.6 0.0014 18.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat RNA_pol_N PF01194.12 EMD60860.1 - 2.6e-29 101.0 0.5 3e-29 100.8 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EMD60860.1 - 0.058 13.4 0.2 0.073 13.1 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF1693 PF07984.7 EMD60860.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) Metallophos PF00149.23 EMD60861.1 - 1.7e-10 40.6 2.3 2.9e-10 39.8 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RCC1 PF00415.13 EMD60862.1 - 1.5e-58 194.7 0.2 1.1e-07 31.8 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMD60862.1 - 8.3e-36 120.8 25.9 2.8e-08 33.1 0.8 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat MIP-T3 PF10243.4 EMD60862.1 - 1.4 7.2 31.8 1.8 6.9 22.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_L13 PF00572.13 EMD60863.1 - 2.4e-38 131.0 0.0 3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sod_Cu PF00080.15 EMD60864.1 - 2.9e-14 53.4 0.0 4.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EMD60864.1 - 5.3e-14 52.1 0.0 8.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_11 PF13414.1 EMD60865.1 - 2.8e-16 58.9 3.8 1.8e-10 40.3 0.1 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMD60865.1 - 3.7e-14 51.6 5.5 4.8e-07 29.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD60865.1 - 1.4e-13 49.6 6.0 1.7e-05 24.3 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMD60865.1 - 2e-11 43.6 0.0 1.7e-06 27.8 0.0 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD60865.1 - 9.8e-09 34.3 1.6 0.0012 18.4 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD60865.1 - 1e-07 31.1 0.1 5.7e-06 25.7 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.19 EMD60865.1 - 1.1e-07 31.3 0.3 2e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 EMD60865.1 - 1.3e-06 28.4 0.1 1.3 9.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD60865.1 - 1.1e-05 25.9 0.5 0.0014 19.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMD60865.1 - 4e-05 23.3 0.0 0.27 11.1 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD60865.1 - 0.00078 19.4 0.1 0.04 14.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD60865.1 - 0.00086 19.7 0.4 0.12 13.0 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD60865.1 - 0.15 12.1 2.9 0.43 10.7 0.0 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Uricase PF01014.13 EMD60867.1 - 6.3e-82 272.4 1.5 5.3e-46 156.1 0.5 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EMD60868.1 - 2.7e-135 450.7 2.0 2.2e-134 447.7 1.2 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EMD60868.1 - 1.5e-86 289.0 0.1 4.1e-85 284.3 0.3 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EMD60868.1 - 2.4e-45 153.1 0.1 7e-42 142.0 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EMD60868.1 - 1.8e-28 98.2 1.2 1.6e-27 95.1 0.1 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EMD60868.1 - 1.3e-09 37.6 11.9 3e-09 36.4 8.2 1.7 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EMD60868.1 - 0.13 12.1 1.7 15 5.5 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat LON PF02190.11 EMD60869.1 - 1.1e-25 90.5 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 EMD60869.1 - 2.2e-13 49.8 18.7 5e-07 29.4 4.0 3.0 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMD60869.1 - 1.7e-12 46.9 21.7 4.1e-08 32.9 7.2 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EMD60869.1 - 2.1e-12 46.8 21.7 1e-07 31.8 7.0 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD60869.1 - 1.7e-11 43.6 18.6 1.4e-06 27.8 5.9 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD60869.1 - 2.8e-10 39.6 18.0 2.1e-05 24.0 6.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD60869.1 - 2.4e-09 36.6 18.4 4.7e-06 26.1 5.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD60869.1 - 5.9e-06 25.8 20.6 0.0063 16.2 4.4 2.7 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.1 EMD60869.1 - 8.4e-05 22.0 14.6 0.014 14.9 1.2 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EMD60869.1 - 0.00039 20.1 14.3 0.011 15.4 2.0 2.8 3 0 0 3 3 3 2 zf-RING of BARD1-type protein U-box PF04564.10 EMD60869.1 - 0.0035 17.2 0.2 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 EMD60869.1 - 0.0042 16.6 13.8 0.0068 15.9 4.2 3.7 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain Slp PF03843.8 EMD60869.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family DZR PF12773.2 EMD60869.1 - 6.7 6.6 12.8 14 5.6 2.9 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 EMD60869.1 - 8.4 6.5 13.5 1.1 9.4 5.2 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger CorA PF01544.13 EMD60870.1 - 0.001 18.2 0.1 0.079 11.9 0.4 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein COG2 PF06148.6 EMD60870.1 - 0.008 16.0 0.5 0.013 15.3 0.3 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 RPW8 PF05659.6 EMD60870.1 - 0.019 14.4 1.6 0.073 12.6 0.8 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Allexi_40kDa PF05549.6 EMD60870.1 - 0.051 12.8 0.2 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein CK2S PF15011.1 EMD60870.1 - 0.054 13.2 0.1 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate AAA_27 PF13514.1 EMD60870.1 - 0.06 11.0 0.3 0.068 10.8 0.2 1.0 1 0 0 1 1 1 0 AAA domain Nsp1_C PF05064.8 EMD60870.1 - 0.078 12.6 0.7 0.22 11.1 0.4 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4298 PF14131.1 EMD60870.1 - 0.098 12.5 0.2 0.8 9.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF948 PF06103.6 EMD60870.1 - 0.1 12.4 0.5 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1825 PF08855.5 EMD60870.1 - 0.12 12.3 0.3 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) DAO PF01266.19 EMD60872.1 - 1.7e-42 145.6 1.7 2.6e-42 144.9 1.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD60872.1 - 5.6e-06 26.3 0.0 0.0006 19.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD60872.1 - 9.4e-05 22.7 0.0 0.62 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD60872.1 - 0.00014 21.0 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD60872.1 - 0.0011 18.9 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMD60872.1 - 0.029 13.0 0.0 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 EMD60872.1 - 0.033 13.6 0.0 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EMD60872.1 - 0.046 13.7 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD60872.1 - 0.06 13.1 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding CRC_subunit PF08624.5 EMD60874.1 - 7.9e-58 194.3 0.1 1.1e-57 193.8 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Daxx PF03344.10 EMD60874.1 - 0.88 7.9 5.2 1.4 7.2 3.6 1.2 1 0 0 1 1 1 0 Daxx Family bZIP_1 PF00170.16 EMD60876.1 - 6.6e-06 26.0 15.4 9.9e-06 25.4 10.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD60876.1 - 0.00031 20.5 20.6 0.00054 19.7 14.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD60876.1 - 0.0012 19.1 10.5 0.0021 18.3 7.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6 PF04111.7 EMD60876.1 - 0.049 12.6 5.3 0.077 12.0 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EMD60876.1 - 0.071 11.7 2.8 0.052 12.2 0.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.7 EMD60876.1 - 1 9.5 8.5 1.8 8.8 5.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF342 PF03961.8 EMD60876.1 - 1.2 7.4 2.9 1.6 7.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RR_TM4-6 PF06459.7 EMD60876.1 - 4.6 7.0 10.8 6.8 6.5 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HET PF06985.6 EMD60878.1 - 1.1e-21 77.4 0.0 3.5e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Utp21 PF04192.7 EMD60879.1 - 5.8e-76 254.7 0.0 8.6e-76 254.1 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EMD60879.1 - 7.8e-19 66.7 38.3 0.00023 20.9 0.0 10.0 11 0 0 11 11 11 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMD60879.1 - 7.8e-05 21.1 0.0 0.00023 19.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EMD60879.1 - 0.0019 17.0 0.8 1.2 7.7 0.0 3.5 3 1 0 4 4 4 2 Nup133 N terminal like Lgl_C PF08596.5 EMD60879.1 - 0.12 10.8 0.0 7.9 4.8 0.0 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal His_Phos_2 PF00328.17 EMD60880.1 - 3e-116 388.5 0.3 4e-116 388.1 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EMD60880.1 - 1.8e-06 27.5 0.0 3.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Glyco_hydro_3 PF00933.16 EMD60881.1 - 4.2e-81 272.2 0.0 5.8e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD60881.1 - 2.4e-46 158.1 0.0 9.3e-46 156.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD60881.1 - 5.7e-22 77.4 0.1 1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Ebola_NP PF05505.7 EMD60883.1 - 0.24 9.4 10.2 0.25 9.3 7.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 EMD60883.1 - 0.53 9.5 14.5 0.73 9.0 10.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EMD60883.1 - 2.5 7.1 11.8 3.4 6.6 8.2 1.2 1 0 0 1 1 1 0 BUD22 FAM177 PF14774.1 EMD60883.1 - 3.3 7.6 11.8 0.35 10.7 1.4 3.0 2 1 1 3 3 3 0 FAM177 family Ndc80_HEC PF03801.8 EMD60885.1 - 3.2e-56 189.1 0.9 7.4e-56 188.0 0.7 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family TraF_2 PF13729.1 EMD60885.1 - 0.086 11.6 2.8 0.47 9.1 0.1 2.6 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Reo_sigmaC PF04582.7 EMD60885.1 - 0.1 11.7 3.9 0.67 9.0 0.3 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EMD60885.1 - 0.28 11.4 12.6 1.4 9.2 0.5 4.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMD60885.1 - 1 8.9 46.3 0.32 10.5 8.1 3.5 3 0 0 3 3 3 0 IncA protein Tweety PF04906.8 EMD60885.1 - 1.8 6.8 4.8 1.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Tweety V_ATPase_I PF01496.14 EMD60885.1 - 3.4 5.3 31.3 0.062 11.1 8.0 2.7 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family FAR1 PF03101.10 EMD60886.1 - 1e-07 32.3 0.9 2e-07 31.4 0.6 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain p450 PF00067.17 EMD60887.1 - 3.1e-49 167.7 0.0 4e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EMD60888.1 - 8.2e-19 67.8 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD60888.1 - 8e-11 41.7 0.0 2.5e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD60888.1 - 8e-08 32.8 0.0 6.7e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD60888.1 - 2.7e-06 27.7 0.0 5.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD60888.1 - 5.1e-05 23.6 0.0 0.00023 21.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMD60888.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EMD60888.1 - 0.00091 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMD60888.1 - 0.00093 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EMD60888.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EMD60888.1 - 0.005 15.9 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EMD60888.1 - 0.014 14.0 0.0 0.031 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.8 EMD60888.1 - 0.02 15.0 0.1 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 EMD60888.1 - 0.023 14.7 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain InvH PF04741.7 EMD60888.1 - 0.086 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Ubie_methyltran PF01209.13 EMD60888.1 - 0.12 11.5 0.0 0.93 8.5 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EMD60888.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Baculo_PEP_C PF04513.7 EMD60889.1 - 0.031 14.0 1.0 0.18 11.6 0.4 2.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3292 PF11696.3 EMD60890.1 - 1.8e-232 772.8 0.0 2.1e-232 772.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Varsurf_PPLC PF03490.8 EMD60891.1 - 0.11 12.1 1.4 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Kelch_3 PF13415.1 EMD60892.1 - 1.2e-25 88.9 10.3 2.9e-07 30.4 0.2 7.3 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EMD60892.1 - 6.3e-24 83.2 5.7 6.3e-09 35.2 0.5 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EMD60892.1 - 8e-22 76.7 6.2 0.00053 19.8 0.0 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMD60892.1 - 9e-22 76.2 3.0 2.2e-08 33.8 0.1 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EMD60892.1 - 9.1e-22 76.5 14.3 9.1e-06 25.3 0.6 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMD60892.1 - 9.6e-11 41.0 10.1 0.0012 18.4 0.1 6.0 7 0 0 7 7 7 3 Kelch motif ABC1 PF03109.11 EMD60893.1 - 1.2e-24 86.5 0.0 3.1e-14 52.9 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 EMD60893.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMD60893.1 - 0.12 11.7 0.0 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pyr_redox_3 PF13738.1 EMD60894.1 - 7.7e-26 91.4 0.0 1.3e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD60894.1 - 6.1e-16 57.7 0.1 7.2e-14 50.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMD60894.1 - 8.1e-14 51.9 0.0 2e-08 34.3 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD60894.1 - 9.5e-10 37.9 0.1 9.8e-09 34.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD60894.1 - 8e-09 35.4 0.0 5.3e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD60894.1 - 1.2e-05 25.1 0.3 2.5 7.8 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMD60894.1 - 1.8e-05 25.0 0.2 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD60894.1 - 2.3e-05 23.6 0.2 0.00026 20.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EMD60894.1 - 0.00016 20.7 0.0 0.0053 15.7 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMD60894.1 - 0.00044 19.2 2.9 0.24 10.2 0.1 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD60894.1 - 0.0014 17.5 0.0 0.003 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMD60894.1 - 0.0026 16.8 0.1 0.025 13.6 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EMD60894.1 - 0.026 13.6 0.0 0.075 12.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMD60894.1 - 0.037 12.4 0.6 2.9 6.2 0.2 3.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 EMD60894.1 - 0.046 13.9 0.0 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pribosyltran PF00156.22 EMD60894.1 - 0.12 12.1 0.0 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Phosphoribosyl transferase domain NAD_binding_10 PF13460.1 EMD60894.1 - 0.13 12.2 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 EMD60894.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EMD60894.1 - 0.16 12.0 0.1 4.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMD60894.1 - 0.5 10.3 1.4 12 5.9 0.0 3.3 4 0 0 4 4 4 0 TrkA-N domain CAP59_mtransfer PF11735.3 EMD60895.1 - 5.6e-63 212.4 0.0 7.3e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SKG6 PF08693.5 EMD60896.1 - 0.0015 17.8 3.7 0.0034 16.6 2.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EMD60896.1 - 0.0021 16.4 0.0 0.0035 15.6 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E HOK_GEF PF01848.11 EMD60896.1 - 0.0025 17.0 1.5 0.005 16.1 1.0 1.5 1 0 0 1 1 1 1 Hok/gef family Protocadherin PF08374.6 EMD60896.1 - 0.0082 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.1 EMD60896.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family RAP1 PF07218.6 EMD60896.1 - 0.024 12.7 9.7 0.03 12.4 6.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EphA2_TM PF14575.1 EMD60896.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 EMD60896.1 - 0.046 13.2 2.6 0.17 11.4 1.8 1.8 1 1 0 1 1 1 0 Podoplanin Syndecan PF01034.15 EMD60896.1 - 0.075 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 EMD60896.1 - 0.096 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family MGC-24 PF05283.6 EMD60896.1 - 0.097 12.4 15.0 0.15 11.8 10.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TrbL PF04610.9 EMD60896.1 - 0.1 12.2 0.4 0.15 11.7 0.3 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Golgin_A5 PF09787.4 EMD60896.1 - 0.12 10.8 3.8 0.17 10.4 2.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FxsA PF04186.8 EMD60896.1 - 0.13 11.8 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Plasmodium_Vir PF05795.6 EMD60896.1 - 0.18 11.0 0.1 0.22 10.6 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 EMD60896.1 - 0.58 8.3 3.5 0.67 8.1 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 EMD60896.1 - 1.8 7.4 8.2 0.38 9.6 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF515 PF04415.7 EMD60896.1 - 6.6 4.8 8.7 10 4.2 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2458 PF10454.4 EMD60897.1 - 6.1e-30 104.0 0.0 7.9e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Lin-8 PF03353.10 EMD60897.1 - 0.17 11.1 2.7 0.28 10.4 1.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist COX14 PF14880.1 EMD60898.1 - 7.1e-17 60.7 1.3 7.1e-17 60.7 0.9 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly RRM_5 PF13893.1 EMD60900.1 - 0.034 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDV3 PF15359.1 EMD60901.1 - 0.078 13.0 0.5 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF3972 PF13118.1 EMD60902.1 - 0.012 15.6 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DivIC PF04977.10 EMD60902.1 - 0.015 14.7 2.2 0.031 13.7 0.5 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF2046 PF09755.4 EMD60902.1 - 0.12 11.2 1.2 0.22 10.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) SlyX PF04102.7 EMD60902.1 - 0.15 12.4 0.6 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 SlyX Paf67 PF10255.4 EMD60904.1 - 5.4e-156 519.5 0.3 6.6e-156 519.2 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EMD60904.1 - 0.056 13.3 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat EthD PF07110.6 EMD60905.1 - 2.4e-16 60.4 0.0 3.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 EthD domain CN_hydrolase PF00795.17 EMD60906.1 - 4.5e-30 104.3 0.0 6.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_6 PF14259.1 EMD60907.1 - 0.00017 21.5 0.0 0.86 9.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BCS1_N PF08740.6 EMD60908.1 - 1.1e-48 165.3 0.0 1.6e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMD60908.1 - 1.4e-18 67.3 0.0 3.3e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMD60908.1 - 4.3e-06 26.2 0.0 1.5e-05 24.4 0.0 2.0 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 EMD60908.1 - 3.5e-05 22.8 0.0 6.2e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMD60908.1 - 0.00012 22.8 0.0 0.00033 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD60908.1 - 0.0014 18.6 0.0 0.0063 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EMD60908.1 - 0.0068 16.1 0.0 0.016 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD60908.1 - 0.0072 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD60908.1 - 0.0088 15.9 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMD60908.1 - 0.018 15.2 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EMD60908.1 - 0.028 14.1 0.0 0.099 12.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EMD60908.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD60908.1 - 0.035 13.6 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EMD60908.1 - 0.041 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.12 EMD60908.1 - 0.055 12.0 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 EMD60908.1 - 0.059 12.3 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EMD60908.1 - 0.07 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMD60908.1 - 0.12 11.8 0.1 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain OPT PF03169.10 EMD60909.1 - 1.1e-196 655.1 30.1 1.3e-196 654.7 20.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lactonase PF10282.4 EMD60911.1 - 9.4e-81 271.5 0.2 1.3e-80 271.1 0.2 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 EMD60911.1 - 0.0037 17.2 7.1 0.1 12.6 0.9 2.9 2 1 0 2 2 2 2 Putative Ig domain FAD_binding_4 PF01565.18 EMD60912.1 - 3.6e-22 78.3 3.5 7.2e-22 77.3 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD60912.1 - 1.5e-14 53.6 0.3 3.6e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD60912.1 - 0.022 13.9 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Bac_surface_Ag PF01103.18 EMD60913.1 - 7.5e-44 150.4 1.5 1.2e-43 149.8 1.0 1.3 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 EMD60914.1 - 4.5e-27 94.2 0.0 6.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3678 PF12435.3 EMD60915.1 - 0.074 12.6 1.3 0.2 11.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3678) Sugar_tr PF00083.19 EMD60916.1 - 4.5e-106 355.1 16.7 5.2e-106 354.9 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD60916.1 - 3e-26 91.9 39.0 7.2e-23 80.8 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMD60916.1 - 0.011 13.8 5.9 0.019 13.0 4.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector BTB PF00651.26 EMD60917.1 - 0.0093 15.9 0.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain SRP-alpha_N PF04086.8 EMD60917.1 - 0.65 9.3 7.9 0.071 12.4 2.4 1.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF676 PF05057.9 EMD60919.1 - 1.3e-41 142.3 0.1 3.9e-28 98.2 0.0 3.3 2 1 1 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMD60919.1 - 0.027 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMD60919.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M20 PF01546.23 EMD60921.1 - 7.2e-20 71.2 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD60921.1 - 3.4e-16 58.9 0.0 5.9e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMD60921.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 FBA PF04300.8 EMD60921.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 F-box associated region Melibiase PF02065.13 EMD60921.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Melibiase TB2_DP1_HVA22 PF03134.14 EMD60922.1 - 2.8e-25 87.8 3.8 4.8e-25 87.1 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nsp1_C PF05064.8 EMD60922.1 - 0.0054 16.3 0.6 0.038 13.6 0.1 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region EMP24_GP25L PF01105.19 EMD60922.1 - 0.23 11.1 0.6 0.35 10.5 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mgm101p PF06420.7 EMD60923.1 - 6.6e-90 298.9 0.0 9.1e-90 298.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 p450 PF00067.17 EMD60924.1 - 3.6e-61 207.0 0.0 4.4e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EMD60925.1 - 0.045 12.2 17.4 0.0086 14.6 9.4 1.6 2 0 0 2 2 2 0 Daxx Family DUF2890 PF11081.3 EMD60925.1 - 0.18 11.8 11.4 0.11 12.5 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) WD40 PF00400.27 EMD60925.1 - 0.19 11.6 3.2 7.3 6.6 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Nop14 PF04147.7 EMD60925.1 - 0.37 8.6 18.4 0.59 7.9 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMD60925.1 - 1.2 7.1 9.3 1.7 6.5 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EMD60925.1 - 3 7.3 16.4 0.34 10.4 8.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein TPR_11 PF13414.1 EMD60926.1 - 0.00019 20.9 5.7 0.57 9.8 0.0 4.2 3 0 0 3 3 3 3 TPR repeat TPR_17 PF13431.1 EMD60926.1 - 0.0056 16.7 0.2 0.078 13.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 EMD60927.1 - 2.2e-156 520.6 0.0 2.8e-156 520.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EMD60927.1 - 7.3e-07 29.2 0.1 2.3 9.0 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD60927.1 - 7.2e-06 25.5 0.0 0.11 12.1 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 EMD60927.1 - 1.3e-05 24.6 0.1 0.085 12.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD60927.1 - 2.5e-05 24.5 0.0 0.012 15.9 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD60927.1 - 0.00012 21.6 1.6 0.041 13.7 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD60927.1 - 0.0023 17.4 0.2 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD60927.1 - 0.0084 16.0 2.5 17 5.4 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD60927.1 - 0.0086 16.7 0.0 49 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD60927.1 - 0.01 15.5 0.5 10 6.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMD60927.1 - 0.025 13.6 0.6 0.7 8.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD60927.1 - 0.041 14.3 0.0 42 4.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.14 EMD60928.1 - 1.2e-39 135.2 0.3 1.4e-39 135.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EMD60928.1 - 0.14 9.6 0.0 0.15 9.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Glyco_hydro_65m PF03632.10 EMD60929.1 - 1.8e-70 237.5 0.1 7.5e-70 235.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EMD60929.1 - 2.4e-34 118.7 0.0 5.5e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 EMD60929.1 - 1.4e-05 24.8 0.2 6.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hydro_65C PF03633.10 EMD60929.1 - 0.00024 21.1 0.1 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HET PF06985.6 EMD60930.1 - 4.1e-32 111.2 0.8 2.9e-31 108.4 0.6 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EMD60931.1 - 3.5e-26 92.0 3.0 4.2e-26 91.7 2.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_1 PF01979.15 EMD60932.1 - 5.5e-44 151.1 0.0 6.7e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMD60932.1 - 4e-06 26.3 0.1 0.00048 19.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMD60932.1 - 1.4e-05 25.3 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EMD60932.1 - 0.00012 21.7 0.0 0.00034 20.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Actin PF00022.14 EMD60933.1 - 4.2e-19 68.2 0.1 7.2e-18 64.1 0.0 2.5 2 1 0 2 2 2 1 Actin DUF966 PF06136.8 EMD60933.1 - 0.032 13.6 0.4 0.058 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) cNMP_binding PF00027.24 EMD60934.1 - 8.7e-38 128.0 0.1 5.8e-19 67.6 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EMD60934.1 - 3.3e-17 63.1 12.0 2.4e-16 60.2 5.1 3.5 2 1 0 2 2 2 1 Patatin-like phospholipase GDC-P PF02347.11 EMD60935.1 - 1.5e-177 590.6 0.0 1.4e-164 547.8 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EMD60935.1 - 7.5e-05 22.0 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD60935.1 - 0.044 12.8 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cyto_heme_lyase PF01265.12 EMD60936.1 - 4e-73 246.2 0.0 4.7e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Yip1 PF04893.12 EMD60937.1 - 1.9e-07 30.7 15.4 9.3e-07 28.5 10.7 2.0 1 1 0 1 1 1 1 Yip1 domain DUF3432 PF11914.3 EMD60937.1 - 0.022 14.7 1.3 0.022 14.7 0.9 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3432) DnaB PF00772.16 EMD60938.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain CCT PF06203.9 EMD60938.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 CCT motif FlhC PF05280.6 EMD60938.1 - 0.4 10.1 3.5 0.73 9.2 2.5 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Pribosyltran PF00156.22 EMD60939.1 - 2.9e-11 43.1 0.2 9.7e-11 41.4 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain F-box-like PF12937.2 EMD60940.1 - 0.00052 19.6 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD60940.1 - 0.00091 18.8 0.0 0.0024 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain HSF_DNA-bind PF00447.12 EMD60941.1 - 1.3e-35 121.7 0.7 2e-35 121.0 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Pectate_lyase_3 PF12708.2 EMD60942.1 - 9.7e-82 274.4 23.4 5e-61 206.6 3.3 2.5 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMD60942.1 - 4e-07 29.3 0.5 0.0086 15.5 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EMD60942.1 - 0.003 17.3 9.5 0.003 17.3 6.6 2.6 2 0 0 2 2 2 1 Right handed beta helix region 4HBT PF03061.17 EMD60943.1 - 7.8e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily DUF566 PF04484.7 EMD60944.1 - 1.5 8.2 11.1 2.1 7.7 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CtnDOT_TraJ PF07863.6 EMD60944.1 - 4.2 7.9 6.9 8.2 6.9 4.8 1.4 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon FAP PF07174.6 EMD60944.1 - 7.7 5.7 18.9 10 5.3 12.8 1.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) RabGAP-TBC PF00566.13 EMD60945.1 - 1.4e-34 119.4 0.0 2.7e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.21 EMD60946.1 - 4e-42 142.9 0.1 4.5e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD60946.1 - 2.4e-05 24.1 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD60946.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMD60946.1 - 0.04 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain BTB PF00651.26 EMD60947.1 - 6.3e-09 35.8 0.1 2.4e-08 33.9 0.0 1.9 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 EMD60947.1 - 0.0073 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Inositol_P PF00459.20 EMD60948.1 - 1e-68 231.6 0.0 1.1e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 EMD60949.1 - 1.6e-09 36.9 29.2 1.6e-09 36.9 20.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD60949.1 - 2e-06 27.4 2.8 2e-06 27.4 1.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EMD60949.1 - 2.1e-05 23.2 12.5 2.1e-05 23.2 8.7 2.7 2 1 2 4 4 4 1 Sugar (and other) transporter DAO PF01266.19 EMD60950.1 - 2.4e-56 191.2 0.0 2.7e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD60950.1 - 0.00061 19.7 0.0 0.63 9.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD60950.1 - 0.0047 16.7 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Epimerase PF01370.16 EMD60950.1 - 0.021 14.2 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GIDA PF01134.17 EMD60950.1 - 0.051 12.4 0.1 0.91 8.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EMD60950.1 - 0.069 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ThiF PF00899.16 EMD60950.1 - 0.1 12.4 0.6 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 ThiF family adh_short PF00106.20 EMD60951.1 - 4.9e-34 117.6 1.4 7e-34 117.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD60951.1 - 2.6e-24 86.3 1.9 6.1e-24 85.1 1.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD60951.1 - 1.4e-15 57.4 0.6 2.2e-15 56.8 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMD60951.1 - 0.0029 17.2 1.1 0.0057 16.3 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMD60951.1 - 0.013 15.6 0.2 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 EMD60951.1 - 0.013 15.3 0.9 0.021 14.6 0.6 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMD60951.1 - 0.018 14.1 0.3 0.03 13.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMD60951.1 - 0.031 13.2 0.3 0.045 12.7 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_25 PF13649.1 EMD60951.1 - 0.058 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TFR_dimer PF04253.10 EMD60952.1 - 3.6e-20 71.7 0.0 1.2e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMD60952.1 - 9.3e-13 48.2 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMD60952.1 - 1.2e-06 28.1 0.0 3.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF4078 PF13300.1 EMD60953.1 - 1.4e-27 95.6 14.5 1.4e-27 95.6 10.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) V_ATPase_I PF01496.14 EMD60953.1 - 0.69 7.6 3.3 1.3 6.7 2.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Homoserine_dh PF00742.14 EMD60954.1 - 2.3e-51 173.9 0.0 3.1e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EMD60954.1 - 3.1e-14 53.3 0.0 6.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_17 PF13207.1 EMD60954.1 - 0.097 13.4 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_trans_4_4 PF13579.1 EMD60955.1 - 5.5 7.1 10.4 1.7 8.7 1.4 2.3 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain ATG11 PF10377.4 EMD60957.1 - 2.3e-41 140.7 0.0 2.3e-41 140.7 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein 11 PUB PF09409.5 EMD60957.1 - 0.024 14.3 0.2 0.77 9.5 0.0 3.4 4 0 0 4 4 4 0 PUB domain Tape_meas_lam_C PF09718.5 EMD60957.1 - 0.077 12.9 4.6 0.15 11.9 0.1 3.3 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CENP-H PF05837.7 EMD60958.1 - 2.5e-22 79.0 9.1 5.1e-22 78.0 1.8 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) BLOC1_2 PF10046.4 EMD60958.1 - 0.023 14.8 1.8 0.023 14.8 1.3 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1028 PF06267.7 EMD60958.1 - 0.034 13.5 0.5 0.034 13.5 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF1028) HR1 PF02185.11 EMD60958.1 - 8 6.2 12.0 1.5 8.5 3.6 2.9 2 1 0 2 2 2 0 Hr1 repeat DUF2605 PF10792.4 EMD60958.1 - 8.9 6.0 9.3 0.92 9.2 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) HMG_box PF00505.14 EMD60960.1 - 3.3e-24 84.9 2.5 3.3e-24 84.9 1.7 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD60960.1 - 9.2e-21 73.9 2.5 9.2e-21 73.9 1.7 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EMD60960.1 - 0.0033 17.1 2.1 0.0033 17.1 1.4 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box 5 Peptidase_S24 PF00717.18 EMD60961.1 - 2.2e-08 33.6 0.0 3.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Sarcolipin PF05366.6 EMD60961.1 - 0.13 11.6 0.2 0.36 10.2 0.2 1.7 1 0 0 1 1 1 0 Sarcolipin Nucleoplasmin PF03066.10 EMD60962.1 - 2 7.9 10.9 3.3 7.2 7.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Dicty_REP PF05086.7 EMD60962.1 - 4 5.0 5.9 5.4 4.6 4.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_4 PF12799.2 EMD60963.1 - 0.00018 21.0 7.6 0.15 11.7 0.1 5.1 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) Rad9 PF04139.8 EMD60964.1 - 1.3e-57 194.7 0.0 1.6e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 DUF605 PF04652.11 EMD60964.1 - 5.7 6.2 11.1 9.1 5.5 7.7 1.3 1 0 0 1 1 1 0 Vta1 like Phos_pyr_kin PF08543.7 EMD60965.1 - 5e-85 284.6 1.5 8.9e-85 283.7 1.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EMD60965.1 - 1.9e-49 168.2 0.7 4.1e-49 167.1 0.1 1.7 2 0 0 2 2 2 1 TENA/THI-4/PQQC family DEAD PF00270.24 EMD60965.1 - 4.2e-45 153.2 0.0 5.4e-44 149.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD60965.1 - 3.9e-27 93.9 0.0 7.9e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PfkB PF00294.19 EMD60965.1 - 1.3e-07 31.0 0.1 2.2e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ResIII PF04851.10 EMD60965.1 - 0.00048 20.0 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EMD60965.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EMD60965.1 - 0.045 12.1 0.0 1.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Virul_fac_BrkB PF03631.10 EMD60966.1 - 0.26 10.6 3.7 2.7 7.2 0.0 2.3 3 0 0 3 3 3 0 Virulence factor BrkB DUF929 PF06053.6 EMD60966.1 - 0.26 10.3 4.8 0.31 10.0 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) MFS_1 PF07690.11 EMD60966.1 - 0.61 8.7 4.7 0.51 8.9 2.9 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Sigma_reg_N PF13800.1 EMD60966.1 - 4.7 7.3 11.0 11 6.1 7.7 1.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2633 PF11119.3 EMD60971.1 - 0.027 14.1 1.5 0.058 13.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Tweety PF04906.8 EMD60972.1 - 0.059 11.7 5.3 0.082 11.3 3.7 1.1 1 0 0 1 1 1 0 Tweety PRT_C PF08372.5 EMD60972.1 - 0.15 11.5 0.3 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal PPR_2 PF13041.1 EMD60974.1 - 4.9e-20 71.2 0.0 4.1e-16 58.6 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 EMD60974.1 - 6.5e-06 25.7 0.3 0.003 17.4 0.0 4.1 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 EMD60974.1 - 4.3e-05 23.4 2.1 0.43 10.9 0.0 5.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EMD60974.1 - 0.00038 19.8 1.1 1.9 8.0 0.0 3.7 3 0 0 3 3 3 2 PPR repeat Rtf2 PF04641.7 EMD60975.1 - 7.7e-54 182.6 15.1 6.4e-53 179.5 10.5 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EMD60975.1 - 4.2e-05 22.9 0.0 0.00059 19.3 0.0 2.5 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EMD60975.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD60975.1 - 0.094 12.5 0.1 0.31 10.8 0.0 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EMD60975.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD60975.1 - 0.11 12.1 0.1 0.3 10.8 0.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Dicty_REP PF05086.7 EMD60975.1 - 2.3 5.8 13.8 3.6 5.2 9.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GET2 PF08690.5 EMD60975.1 - 3.5 6.7 8.5 5.4 6.1 5.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Mucin PF01456.12 EMD60975.1 - 5.3 6.8 18.0 0.38 10.5 9.2 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein MRP-S31 PF15433.1 EMD60975.1 - 6 6.1 13.2 11 5.3 9.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAP_assoc PF03828.14 EMD60976.1 - 1.2e-19 69.9 0.0 2.6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMD60976.1 - 0.00014 22.1 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EMD60976.1 - 0.0024 16.7 0.0 0.76 8.5 0.1 2.5 2 0 0 2 2 2 2 Poly(A) polymerase central domain DUF383 PF04063.9 EMD60978.1 - 3.3e-69 232.2 0.1 1.8e-68 229.8 0.0 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EMD60978.1 - 5.2e-23 80.3 3.3 1.4e-22 79.0 2.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 EMD60978.1 - 0.0075 16.5 2.0 0.96 9.7 0.5 3.2 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EMD60978.1 - 0.13 12.3 0.3 27 5.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat PEP-utilisers_N PF05524.8 EMD60978.1 - 0.17 11.7 1.8 0.48 10.2 1.3 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Abhydrolase_6 PF12697.2 EMD60980.1 - 3.2e-19 69.7 0.1 3.9e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD60980.1 - 6.6e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD60980.1 - 4.9e-06 26.3 0.0 8.1e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMD60980.1 - 0.0052 16.2 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF1057 PF06342.7 EMD60980.1 - 0.078 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PLRV_ORF5 PF01690.12 EMD60981.1 - 9.1 5.2 6.2 13 4.7 4.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ETF_QO PF05187.8 EMD60986.1 - 1.5e-48 163.3 0.1 3.2e-48 162.2 0.0 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EMD60986.1 - 7.4e-08 31.6 0.6 0.00036 19.5 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD60986.1 - 6.5e-07 28.5 1.0 0.00029 19.8 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD60986.1 - 3.9e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMD60986.1 - 0.00018 20.7 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD60986.1 - 0.00025 19.6 0.4 0.00038 19.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMD60986.1 - 0.00033 19.8 0.2 0.0011 18.1 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMD60986.1 - 0.00043 20.2 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD60986.1 - 0.00046 19.3 0.0 0.00072 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD60986.1 - 0.0011 19.3 0.3 1.6 9.1 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD60986.1 - 0.0039 17.2 0.0 0.0098 15.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD60986.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMD60986.1 - 0.016 14.1 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.2 EMD60986.1 - 0.02 15.2 0.9 0.043 14.1 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.9 EMD60986.1 - 0.047 12.3 0.1 0.18 10.3 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EMD60986.1 - 0.12 11.1 0.5 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.17 EMD60987.1 - 1.1e-22 79.4 0.0 1.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD60987.1 - 2.4e-15 56.2 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD60987.1 - 4.8e-12 45.5 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L44 PF00935.14 EMD60988.1 - 0.0091 15.9 2.8 0.0091 15.9 2.0 2.4 2 1 1 3 3 3 1 Ribosomal protein L44 zf-C2HC_2 PF13913.1 EMD60988.1 - 0.22 11.2 3.8 8 6.2 0.8 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.1 EMD60988.1 - 2.8 8.2 7.7 7.5 6.8 0.2 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF1014 PF06244.7 EMD60991.1 - 0.0065 16.6 5.4 0.012 15.8 3.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Dioxygenase_C PF00775.16 EMD60992.1 - 9.1e-53 178.2 0.0 1.3e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMD60992.1 - 3.5e-17 62.1 0.0 6.9e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMD60992.1 - 0.0049 16.8 0.1 0.016 15.2 0.1 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cyt-b5 PF00173.23 EMD60994.1 - 5.7e-14 51.6 0.0 6.8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3445 PF11927.3 EMD60995.1 - 6.2e-69 232.1 0.0 7.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pkinase PF00069.20 EMD60996.1 - 2.9e-49 167.5 0.0 1.3e-48 165.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD60996.1 - 1.2e-27 96.6 0.0 1.9e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD60996.1 - 4.9e-05 22.4 0.0 9.7e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD60996.1 - 0.0058 16.4 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMD60996.1 - 0.064 12.0 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EMD60996.1 - 0.069 12.4 0.4 0.32 10.3 0.2 2.1 1 1 0 1 1 1 0 RIO1 family Zn_ribbon_recom PF13408.1 EMD60997.1 - 0.037 14.2 0.7 0.063 13.5 0.5 1.4 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF3425 PF11905.3 EMD60999.1 - 4.1e-14 52.6 1.8 8.5e-14 51.6 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.13 EMD60999.1 - 2.7e-09 36.7 10.9 2.7e-09 36.7 7.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAPL PF07814.8 EMD61001.1 - 0.09 11.4 1.7 0.087 11.5 1.2 1.0 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin DUF2547 PF10818.3 EMD61001.1 - 0.37 11.4 2.9 0.51 10.9 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) p450 PF00067.17 EMD61003.1 - 5.8e-72 242.6 0.0 7.2e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fasciclin PF02469.17 EMD61004.1 - 8.4e-52 174.5 4.1 3.4e-28 98.2 0.3 2.1 2 0 0 2 2 2 2 Fasciclin domain Pol_alpha_B_N PF08418.5 EMD61005.1 - 0.14 11.7 11.8 0.19 11.2 8.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EMD61005.1 - 2.2 7.5 16.8 2.8 7.2 11.6 1.0 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EMD61005.1 - 5.2 5.4 25.6 6 5.2 17.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DHquinase_I PF01487.10 EMD61007.1 - 7.5e-41 140.2 0.0 1.4e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EMD61007.1 - 6.1e-19 67.8 0.0 1.5e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMD61007.1 - 5.4e-14 52.4 0.0 5.2e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.17 EMD61007.1 - 9.1e-14 51.6 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase F420_oxidored PF03807.12 EMD61007.1 - 0.00019 21.7 0.0 0.00079 19.8 0.0 2.0 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EMD61007.1 - 0.0015 17.6 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase AAA_17 PF13207.1 EMD61007.1 - 0.012 16.4 0.0 0.057 14.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD61007.1 - 0.022 14.5 0.0 0.079 12.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMD61007.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD61007.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EMD61007.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 EMD61007.1 - 0.12 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ThiF PF00899.16 EMD61007.1 - 0.13 12.0 2.3 0.19 11.5 0.5 2.0 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 EMD61008.1 - 2.5e-12 46.2 0.1 9.8e-12 44.2 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Desmo_N PF06771.6 EMD61008.1 - 0.14 12.0 0.4 0.35 10.8 0.3 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus MerR_2 PF13591.1 EMD61009.1 - 0.18 11.4 0.0 0.46 10.1 0.1 1.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF3112 PF11309.3 EMD61010.1 - 4.5e-37 127.2 19.8 7.1e-36 123.4 6.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) YqgF PF14639.1 EMD61010.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DUF3087 PF11286.3 EMD61010.1 - 3.2 6.9 8.7 3.4 6.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) Vps35 PF03635.12 EMD61011.1 - 0 1041.3 5.1 0 1041.1 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Dicty_REP PF05086.7 EMD61011.1 - 0.062 11.0 1.9 0.095 10.4 1.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Daxx PF03344.10 EMD61011.1 - 0.14 10.6 11.3 0.21 10.0 7.8 1.1 1 0 0 1 1 1 0 Daxx Family RuvA_N PF01330.16 EMD61012.1 - 0.049 13.4 0.0 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 RuvA N terminal domain Herpes_UL32 PF06070.6 EMD61012.1 - 0.48 8.8 7.4 0.47 8.8 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 MSP1_C PF07462.6 EMD61012.1 - 9.1 4.5 7.8 12 4.1 5.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HET PF06985.6 EMD61013.1 - 3.6e-17 62.8 0.0 3.9e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FtsK_SpoIIIE PF01580.13 EMD61013.1 - 7.2e-05 22.3 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family KR PF08659.5 EMD61015.1 - 8.5e-61 204.7 0.3 8.5e-61 204.7 0.2 1.9 2 0 0 2 2 1 1 KR domain ketoacyl-synt PF00109.21 EMD61015.1 - 7.5e-51 173.0 0.8 3.1e-50 171.0 0.1 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD61015.1 - 2.7e-49 168.2 0.0 4.7e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMD61015.1 - 1.2e-45 155.3 4.2 3.5e-45 153.9 0.2 2.8 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EMD61015.1 - 3.5e-41 141.2 0.1 5.8e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMD61015.1 - 2.1e-37 127.5 0.1 5.5e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD61015.1 - 5.6e-21 74.4 0.1 1.8e-20 72.8 0.1 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMD61015.1 - 1.1e-14 54.7 0.0 2.7e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD61015.1 - 9.9e-09 35.1 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMD61015.1 - 6.4e-08 32.3 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EMD61015.1 - 1.7e-07 31.6 0.0 6.3e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD61015.1 - 4.4e-06 27.6 0.0 3.2e-05 24.8 0.0 2.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EMD61015.1 - 6e-06 26.8 0.0 2.6e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61015.1 - 3.4e-05 23.4 0.0 7.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EMD61015.1 - 0.00037 19.5 0.0 0.00076 18.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EMD61015.1 - 0.0012 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EMD61015.1 - 0.0023 17.1 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 EMD61015.1 - 0.0048 16.5 0.2 0.018 14.6 0.1 2.0 2 0 0 2 2 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.7 EMD61015.1 - 0.78 8.5 0.0 1.9 7.2 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase RDV-p3 PF09231.5 EMD61015.1 - 4.8 4.4 0.0 7.2 3.8 0.0 1.1 1 0 0 1 1 1 0 Rice dwarf virus p3 p450 PF00067.17 EMD61016.1 - 5.9e-50 170.1 0.0 7.1e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMD61017.1 - 7.6e-77 258.7 0.0 9.7e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMD61018.1 - 1.5e-15 57.5 0.1 3.8e-15 56.1 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD61018.1 - 6.6e-06 25.9 0.0 9.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMD61018.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EMD61019.1 - 2.5e-23 82.8 0.1 3.8e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61019.1 - 5.7e-09 36.0 0.1 8.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61019.1 - 8.1e-08 32.1 0.1 2.5e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD61019.1 - 3e-05 24.1 0.0 0.00018 21.6 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD61019.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD61019.1 - 0.023 13.8 0.2 0.037 13.1 0.2 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 EMD61019.1 - 0.036 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Choline_kin_N PF04428.9 EMD61019.1 - 0.12 11.8 0.0 0.42 10.1 0.0 2.0 1 0 0 1 1 1 0 Choline kinase N terminus Methyltransf_2 PF00891.13 EMD61020.1 - 1.1e-26 93.4 0.0 1.7e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMD61020.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain HpcH_HpaI PF03328.9 EMD61021.1 - 2.2e-45 154.2 0.0 2.7e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Gemini_AC4_5 PF04807.7 EMD61021.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region G10 PF01125.12 EMD61021.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 G10 protein TMEM154 PF15102.1 EMD61022.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Fe-S_biosyn PF01521.15 EMD61024.1 - 6.1e-12 45.4 0.0 8.2e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.14 EMD61025.1 - 1.6e-13 50.1 0.0 5e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMD61025.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DNA_pol_B PF00136.16 EMD61026.1 - 3.4e-110 369.0 2.6 8.6e-110 367.6 1.8 1.7 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EMD61026.1 - 2.2e-59 199.9 0.0 5.4e-59 198.7 0.0 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EMD61026.1 - 9e-43 146.3 0.0 2.1e-42 145.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EMD61026.1 - 1.6e-24 85.5 9.3 5.6e-24 83.7 6.5 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal RNase_T PF00929.19 EMD61027.1 - 7.4e-18 65.3 0.5 8.6e-18 65.1 0.3 1.0 1 0 0 1 1 1 1 Exonuclease Lipase_GDSL PF00657.17 EMD61028.1 - 2.3e-09 37.4 2.2 6.7e-09 35.9 1.5 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMD61028.1 - 4.9e-09 36.5 0.3 6.2e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Inhibitor_I78 PF11720.3 EMD61028.1 - 0.042 13.5 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I78 family bZIP_1 PF00170.16 EMD61029.1 - 1.9e-09 37.3 10.0 8.2e-09 35.2 6.9 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF3158 PF11358.3 EMD61029.1 - 0.022 14.2 0.2 0.043 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) bZIP_2 PF07716.10 EMD61029.1 - 0.036 13.8 10.7 0.84 9.5 7.4 2.4 1 1 0 1 1 1 0 Basic region leucine zipper DUF501 PF04417.7 EMD61029.1 - 0.23 11.3 2.5 0.25 11.1 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF501) DUF1043 PF06295.7 EMD61029.1 - 3.8 7.1 6.4 9.4 5.8 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Pterin_4a PF01329.14 EMD61030.1 - 4.7e-27 93.5 0.2 6.7e-27 93.0 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Actin PF00022.14 EMD61031.1 - 5.6e-25 87.5 0.0 4.2e-12 45.1 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EMD61031.1 - 0.002 16.8 0.0 0.042 12.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF1765 PF08578.5 EMD61033.1 - 4.5e-39 133.3 3.5 8.4e-39 132.5 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 EMD61034.1 - 8.1e-28 95.9 0.8 1.1e-27 95.4 0.6 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EMD61034.1 - 0.012 15.4 0.3 0.017 14.9 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 EMD61035.1 - 1e-32 111.7 0.5 1.1e-16 60.3 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMD61035.1 - 1.2e-13 50.0 0.9 2.2e-13 49.2 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.15 EMD61035.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF2296 PF10058.4 EMD61035.1 - 0.035 13.8 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) CUE PF02845.11 EMD61037.1 - 1.6e-09 37.0 0.0 2.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Metal_resist PF13801.1 EMD61037.1 - 0.069 13.1 0.3 0.069 13.1 0.2 3.2 3 0 0 3 3 3 0 Heavy-metal resistance MULE PF10551.4 EMD61038.1 - 0.046 13.8 0.0 0.55 10.4 0.0 2.3 1 1 1 2 2 2 0 MULE transposase domain Aldo_ket_red PF00248.16 EMD61039.1 - 2.4e-55 187.3 0.0 2.8e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EMD61040.1 - 2.4e-22 78.7 0.0 5.2e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD61040.1 - 7.7e-19 67.1 0.0 3.1e-18 65.2 0.0 2.1 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EMD61040.1 - 0.00093 19.4 0.0 0.26 11.5 0.0 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD61040.1 - 0.0089 16.4 0.0 0.2 12.0 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Ribosomal_S28e PF01200.13 EMD61042.1 - 1.4e-32 111.2 1.7 1.5e-32 111.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Pectate_lyase PF03211.8 EMD61043.1 - 3.5e-52 176.9 0.7 4.9e-52 176.4 0.5 1.1 1 0 0 1 1 1 1 Pectate lyase Epimerase PF01370.16 EMD61044.1 - 8.1e-15 54.8 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD61044.1 - 4.7e-10 38.6 0.0 6.6e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD61044.1 - 9.1e-10 37.8 0.0 2.9e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMD61044.1 - 7.3e-09 35.8 0.0 1.7e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD61044.1 - 0.0027 16.6 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMD61044.1 - 0.006 16.5 0.1 0.029 14.3 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMD61044.1 - 0.012 14.8 0.1 0.022 14.0 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family DAO PF01266.19 EMD61045.1 - 1.1e-46 159.3 0.0 1.3e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD61045.1 - 1.9e-05 24.6 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD61045.1 - 7.4e-05 22.5 0.0 0.0014 18.4 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EMD61045.1 - 0.00054 18.9 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMD61045.1 - 0.0016 18.3 0.0 1.3 8.8 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD61045.1 - 0.024 14.6 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EMD61045.1 - 0.042 12.9 0.0 0.77 8.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.1 EMD61045.1 - 0.073 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMD61045.1 - 0.087 11.9 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Glucodextran_N PF09137.6 EMD61045.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Glucodextranase, domain N Methyltransf_23 PF13489.1 EMD61046.1 - 5.6e-20 71.6 0.0 9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD61046.1 - 1.2e-06 28.8 0.0 3.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61046.1 - 1.4e-05 25.4 0.0 2.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61046.1 - 0.0002 21.9 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61046.1 - 0.00039 20.0 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD61046.1 - 0.045 14.1 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF1286 PF06939.6 EMD61049.1 - 0.054 13.6 0.1 0.097 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1286) DUF2235 PF09994.4 EMD61050.1 - 5.1e-72 242.5 0.0 7.6e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) p450 PF00067.17 EMD61051.1 - 3.7e-23 81.7 0.1 5.7e-23 81.1 0.1 1.2 1 1 0 1 1 1 1 Cytochrome P450 Rubredoxin PF00301.15 EMD61053.1 - 0.0069 16.2 0.2 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Rubredoxin SAGA-Tad1 PF12767.2 EMD61053.1 - 0.033 13.8 3.6 0.051 13.2 2.5 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SAPS PF04499.10 EMD61053.1 - 0.064 11.8 3.4 0.083 11.5 2.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 EMD61053.1 - 0.089 12.6 3.2 0.17 11.7 2.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 EMD61053.1 - 0.26 10.6 15.2 0.36 10.1 10.5 1.1 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 EMD61053.1 - 0.27 8.8 10.1 0.37 8.4 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 EMD61053.1 - 0.29 10.4 12.6 0.43 9.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EMD61053.1 - 5.1 4.8 14.5 6.6 4.5 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMD61053.1 - 7.2 4.5 8.8 11 3.8 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EMD61053.1 - 7.9 4.6 11.4 10 4.2 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 EMD61054.1 - 3.2e-70 236.2 0.0 5.1e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD61054.1 - 9.5e-15 54.2 0.0 2.8e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD61054.1 - 1.9e-06 27.8 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD61054.1 - 0.0062 16.0 0.0 0.17 11.3 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase TBPIP PF07106.8 EMD61054.1 - 0.035 13.6 4.2 0.12 11.9 2.9 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EMD61054.1 - 0.16 11.7 8.9 5.2 6.9 2.7 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 EMD61054.1 - 0.91 9.3 8.0 0.85 9.4 0.1 3.0 2 1 1 3 3 3 0 Prefoldin subunit Asp-B-Hydro_N PF05279.6 EMD61055.1 - 0.014 15.2 1.3 0.022 14.5 0.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FA_hydroxylase PF04116.8 EMD61056.1 - 1.2e-17 64.3 19.1 1.2e-17 64.3 13.2 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Bystin PF05291.6 EMD61056.1 - 0.052 12.4 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Bystin Paf1 PF03985.8 EMD61057.1 - 8.3e-44 150.0 0.0 1.3e-35 122.9 0.0 3.1 2 1 0 2 2 2 2 Paf1 Dapper PF15268.1 EMD61059.1 - 0.079 11.7 0.6 0.09 11.5 0.4 1.0 1 0 0 1 1 1 0 Dapper HlyIII PF03006.15 EMD61060.1 - 5.1e-54 183.0 18.4 6.1e-54 182.7 12.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4293 PF14126.1 EMD61060.1 - 0.1 12.5 0.9 0.25 11.2 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) UPF0122 PF04297.9 EMD61061.1 - 0.031 14.2 0.5 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like RNA_pol_3_Rpc31 PF11705.3 EMD61062.1 - 2.5e-34 119.2 19.3 8.3e-34 117.5 13.4 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 EMD61062.1 - 0.0076 15.3 12.7 0.0096 15.0 8.8 1.1 1 0 0 1 1 1 1 BUD22 FCH PF00611.18 EMD61063.1 - 5.1e-18 65.0 0.0 1.5e-17 63.5 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EMD61063.1 - 1.8e-12 46.4 0.0 3.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD61063.1 - 2.6e-11 42.8 0.0 8.6e-11 41.1 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMD61063.1 - 1.2e-10 40.8 0.0 2.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PKK PF12474.3 EMD61063.1 - 0.2 11.3 15.6 0.9 9.2 2.5 3.2 2 1 0 2 2 2 0 Polo kinase kinase Not1 PF04054.10 EMD61064.1 - 4.9e-119 397.5 0.2 1.4e-118 396.1 0.2 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EMD61064.1 - 8.5e-48 161.7 2.8 2.6e-47 160.2 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Macoilin PF09726.4 EMD61064.1 - 3.4 5.8 7.8 5.6 5.1 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Occludin_ELL PF07303.8 EMD61068.1 - 0.23 12.2 2.6 0.22 12.2 0.6 1.9 2 1 0 2 2 2 0 Occludin homology domain PP28 PF10252.4 EMD61068.1 - 0.33 11.0 0.2 0.33 11.0 0.1 2.4 2 1 1 3 3 3 0 Casein kinase substrate phosphoprotein PP28 DUF2217 PF10265.4 EMD61068.1 - 1.1 7.9 12.4 1.2 7.8 8.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ebola_NP PF05505.7 EMD61068.1 - 1.4 6.8 6.4 1.7 6.6 4.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Macoilin PF09726.4 EMD61068.1 - 6.3 4.9 14.0 7.1 4.7 9.7 1.1 1 0 0 1 1 1 0 Transmembrane protein YrhK PF14145.1 EMD61069.1 - 0.00053 19.5 18.9 2.1 8.0 1.8 4.8 3 2 0 3 3 3 3 YrhK-like protein Pkinase PF00069.20 EMD61071.1 - 3.3e-60 203.4 0.0 4.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61071.1 - 9.6e-33 113.3 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD61071.1 - 0.00022 20.2 0.0 0.001 18.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EMD61071.1 - 0.0004 20.2 0.0 0.0013 18.5 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD61071.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.13 EMD61074.1 - 4.6e-18 65.0 0.2 7.4e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliS PF02561.9 EMD61074.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FliS SOG2 PF10428.4 EMD61074.1 - 4.2 5.9 12.5 0.64 8.6 1.0 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Adaptin_N PF01602.15 EMD61075.1 - 7.9e-119 397.3 8.1 9.7e-119 397.0 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EMD61075.1 - 1.2e-46 157.3 0.0 4.5e-46 155.4 0.0 2.1 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EMD61075.1 - 2.3e-23 82.6 0.1 5.5e-23 81.4 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EMD61075.1 - 0.021 15.0 3.3 0.65 10.3 0.1 3.9 3 1 1 4 4 4 0 HEAT repeats Cnd1 PF12717.2 EMD61075.1 - 0.031 14.1 0.3 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1096 PF06493.6 EMD61076.1 - 6.3 6.8 28.3 9.9 6.2 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Arm PF00514.18 EMD61077.1 - 0.0022 17.7 2.9 1.9 8.4 0.1 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DPM3 PF08285.6 EMD61078.1 - 6.7e-36 122.0 0.2 7.4e-36 121.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.4 EMD61079.1 - 3.4e-27 93.6 4.0 9.4e-27 92.2 2.8 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal CCDC-167 PF15188.1 EMD61080.1 - 0.021 14.7 2.6 0.039 13.8 1.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4238 PF14022.1 EMD61080.1 - 0.054 12.7 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) IncA PF04156.9 EMD61080.1 - 0.091 12.3 0.6 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EMD61080.1 - 0.32 10.6 5.3 0.14 11.8 1.7 1.7 2 0 0 2 2 2 0 Mnd1 family Ala_racemase_N PF01168.15 EMD61081.1 - 1.9e-45 155.0 0.1 2.3e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Aldose_epim PF01263.15 EMD61082.1 - 8.7e-45 153.0 0.4 9.7e-45 152.9 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4131 PF13567.1 EMD61084.1 - 9.7 5.5 9.5 14 5.0 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MS_channel PF00924.13 EMD61086.1 - 8.5e-16 57.8 1.0 1.6e-15 56.9 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMD61086.1 - 0.0006 18.9 0.2 0.0015 17.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMD61086.1 - 0.021 14.6 0.1 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EMD61086.1 - 0.039 14.0 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EMD61086.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 EF hand ELH PF02323.10 EMD61087.1 - 0.052 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor FA_desaturase PF00487.19 EMD61088.1 - 0.055 12.8 0.6 0.08 12.3 0.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF1218 PF06749.7 EMD61088.1 - 4.2 7.9 5.7 20 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) PIG-Y PF15159.1 EMD61088.1 - 6.6 7.0 7.0 28 5.0 4.8 2.0 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Cation_efflux PF01545.16 EMD61089.1 - 6.7e-26 91.0 5.0 9.2e-26 90.5 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family IBR PF01485.16 EMD61090.1 - 3.5e-15 55.6 40.5 8.6e-09 35.1 6.1 3.3 3 0 0 3 3 3 3 IBR domain zf-C3HC4_2 PF13923.1 EMD61090.1 - 0.015 15.3 2.7 0.015 15.3 1.8 4.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SEEK1 PF15357.1 EMD61090.1 - 0.12 12.2 1.8 0.24 11.3 1.3 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Cyclin_N PF00134.18 EMD61091.1 - 0.005 16.3 0.0 0.12 11.9 0.0 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EMD61091.1 - 0.072 12.9 0.4 8.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Rab_eff_C PF04698.7 EMD61093.1 - 0.13 10.3 0.5 0.16 10.0 0.3 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus PAT1 PF09770.4 EMD61094.1 - 10 4.2 18.4 12 3.9 12.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ish1 PF10281.4 EMD61095.1 - 4.9e-45 151.2 18.0 1.3e-14 53.9 0.0 5.5 5 0 0 5 5 5 4 Putative stress-responsive nuclear envelope protein Slx4 PF09494.5 EMD61095.1 - 0.00042 20.0 2.0 2 8.2 0.0 4.2 4 0 0 4 4 4 1 Slx4 endonuclease SAP PF02037.22 EMD61095.1 - 0.0017 17.8 0.0 1.2 8.6 0.0 3.8 4 0 0 4 4 4 1 SAP domain HeH PF12949.2 EMD61095.1 - 0.0074 15.8 0.0 4.3 6.9 0.0 3.4 4 0 0 4 4 4 2 HeH/LEM domain SR-25 PF10500.4 EMD61096.1 - 3.3 7.1 12.9 0.3 10.5 4.9 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ogr_Delta PF04606.7 EMD61099.1 - 0.041 13.5 0.4 2 8.1 0.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger p450 PF00067.17 EMD61101.1 - 8.5e-56 189.3 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3433 PF11915.3 EMD61102.1 - 1e-50 169.8 16.7 5.7e-28 96.9 1.6 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF4231 PF14015.1 EMD61102.1 - 0.073 13.0 4.9 0.42 10.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Arf PF00025.16 EMD61103.1 - 1.9e-74 248.6 0.0 2.1e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD61103.1 - 1.6e-12 47.0 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMD61103.1 - 3.8e-11 42.3 0.6 2.6e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMD61103.1 - 7.9e-11 41.6 0.0 9.3e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMD61103.1 - 3e-09 36.3 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD61103.1 - 1.7e-08 34.9 0.0 2.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD61103.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD61103.1 - 3.2e-05 23.4 0.0 0.0053 16.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMD61103.1 - 0.0074 15.5 0.7 0.034 13.4 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EMD61103.1 - 0.079 13.4 0.2 0.24 11.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) p450 PF00067.17 EMD61105.1 - 2.7e-36 125.0 0.0 3.6e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EMD61106.1 - 2.4e-122 408.7 23.6 2.7e-122 408.5 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61106.1 - 6.5e-21 74.4 39.6 5e-18 64.9 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EMD61106.1 - 2.6 7.4 10.0 4.4 6.6 0.3 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EMD61107.1 - 2.2e-41 141.7 71.7 1.3e-33 116.2 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM237 PF15383.1 EMD61107.1 - 0.58 9.2 4.3 3.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 237 DUF1736 PF08409.6 EMD61108.1 - 0.053 13.1 0.7 0.088 12.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) HlyIII PF03006.15 EMD61110.1 - 1.3e-62 211.1 12.4 1.5e-62 210.9 8.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EMD61110.1 - 0.019 14.8 0.6 0.019 14.8 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4405 PF14358.1 EMD61110.1 - 0.41 10.8 9.5 2.2 8.4 0.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) SAC3_GANP PF03399.11 EMD61111.1 - 9.4e-05 22.0 0.0 0.00023 20.7 0.0 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMD61111.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Brix PF04427.13 EMD61112.1 - 4.2e-59 199.4 0.0 5.4e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain RNA_pol_3_Rpc31 PF11705.3 EMD61112.1 - 6.5 6.6 28.0 12 5.7 19.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DEAD PF00270.24 EMD61113.1 - 5.9e-47 159.2 0.0 1e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61113.1 - 1.7e-26 91.9 0.0 5.1e-26 90.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMD61113.1 - 0.049 12.4 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EMD61113.1 - 0.085 12.6 0.0 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF336 PF03928.9 EMD61114.1 - 8.8e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF2493 PF10686.4 EMD61114.1 - 0.099 12.2 0.2 0.73 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Ferritin_2 PF13668.1 EMD61115.1 - 8.7e-16 58.1 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain TRM PF02005.11 EMD61116.1 - 1.8e-115 385.8 0.0 4.3e-100 335.2 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EMD61116.1 - 4.3e-05 23.1 0.0 0.0003 20.4 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EMD61116.1 - 0.00072 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61116.1 - 0.0031 18.0 0.0 0.0065 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD61116.1 - 0.009 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EMD61116.1 - 0.057 12.4 0.1 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Cons_hypoth95 PF03602.10 EMD61116.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EMD61116.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2156 PF09924.4 EMD61118.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) SLAC1 PF03595.12 EMD61119.1 - 3.3e-78 262.6 43.9 3.9e-78 262.3 30.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel p450 PF00067.17 EMD61120.1 - 7.3e-70 235.7 0.0 9.3e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BioW PF03744.8 EMD61120.1 - 0.16 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase BTB PF00651.26 EMD61121.1 - 4.4e-07 29.8 0.0 6.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TIMELESS PF04821.9 EMD61122.1 - 6e-88 294.5 0.0 1.3e-87 293.4 0.0 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EMD61122.1 - 1.3e-27 97.0 0.8 1.3e-27 97.0 0.6 4.6 3 1 1 4 4 4 1 Timeless protein C terminal region 3HCDH_N PF02737.13 EMD61123.1 - 2.3e-52 177.2 0.2 3e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMD61123.1 - 1.1e-33 115.5 0.0 2.2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EMD61123.1 - 0.00063 19.5 0.2 0.0012 18.5 0.2 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EMD61123.1 - 0.00064 19.5 0.1 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMD61123.1 - 0.0019 17.3 0.3 0.0071 15.5 0.1 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMD61123.1 - 0.051 14.0 0.1 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EMD61123.1 - 0.056 12.4 0.1 0.068 12.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD61123.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FeoC PF09012.5 EMD61123.1 - 0.067 12.9 0.0 3 7.6 0.0 2.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Dmrt1 PF12374.3 EMD61124.1 - 0.3 11.4 2.2 0.51 10.7 1.5 1.4 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Pex14_N PF04695.8 EMD61126.1 - 9.6e-40 135.7 8.6 6.3e-39 133.1 0.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EMD61126.1 - 0.032 14.0 0.6 5.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEP-utilisers_N PF05524.8 EMD61126.1 - 0.054 13.3 0.1 3 7.6 0.2 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF3584 PF12128.3 EMD61126.1 - 0.062 10.6 4.6 0.085 10.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 EMD61126.1 - 0.1 11.8 5.2 0.22 10.7 3.6 1.5 1 1 0 1 1 1 0 Laminin Domain I EamA PF00892.15 EMD61126.1 - 0.22 11.5 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family CHZ PF09649.5 EMD61127.1 - 0.00071 18.7 4.3 0.0013 17.8 3.0 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ DUF465 PF04325.8 EMD61128.1 - 0.0037 16.9 1.5 0.008 15.8 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF465) Cgr1 PF03879.9 EMD61128.1 - 0.0044 17.1 0.4 0.0088 16.2 0.3 1.4 1 0 0 1 1 1 1 Cgr1 family zf-PARP PF00645.13 EMD61129.1 - 3.5e-20 72.0 0.2 7.1e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Seipin PF06775.9 EMD61132.1 - 5.5e-53 179.4 0.0 7.1e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Abhydrolase_3 PF07859.8 EMD61133.1 - 1.8e-37 128.9 0.0 4.2e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD61133.1 - 0.00025 20.8 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SPR1 PF15356.1 EMD61133.1 - 0.21 11.9 6.1 1.9 8.8 1.4 2.7 1 1 1 2 2 2 0 Psoriasis susceptibility locus 2 DUF2424 PF10340.4 EMD61133.1 - 0.21 10.1 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Cyclin_N PF00134.18 EMD61134.1 - 3.6e-14 52.4 0.2 1.3e-13 50.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMD61134.1 - 3.3e-06 27.0 1.4 0.00022 21.1 0.0 2.8 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EMD61134.1 - 0.0002 21.1 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat UPF0016 PF01169.14 EMD61135.1 - 1.6e-40 137.1 24.2 1.7e-20 72.9 4.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-binding PF00249.26 EMD61136.1 - 0.12 12.4 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2256 PF10013.4 EMD61137.1 - 9e-05 22.1 3.2 0.0003 20.4 2.2 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 EMD61137.1 - 0.0067 15.6 0.3 0.016 14.5 0.2 1.6 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EMD61137.1 - 0.5 10.2 4.2 1.4 8.8 2.9 1.7 1 0 0 1 1 1 0 MYND finger Fumble PF03630.9 EMD61138.1 - 8.8e-130 432.5 0.0 1e-128 428.9 0.0 2.0 1 1 0 1 1 1 1 Fumble Ank_2 PF12796.2 EMD61140.1 - 2.7e-16 59.6 1.1 1.2e-14 54.3 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD61140.1 - 1e-14 53.4 2.9 3.9e-05 23.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMD61140.1 - 1.7e-10 41.1 0.1 9.4e-08 32.3 0.0 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD61140.1 - 2e-08 34.2 0.6 0.0024 18.0 0.0 4.0 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD61140.1 - 1e-07 31.4 2.3 0.064 13.5 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat HET PF06985.6 EMD61141.1 - 1.2e-22 80.6 0.6 2e-22 79.8 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EMD61142.1 - 1.8e-07 31.1 0.0 8.6e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family F_bP_aldolase PF01116.15 EMD61143.1 - 7.1e-102 340.3 0.0 8e-102 340.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ribosomal_L9_N PF01281.14 EMD61144.1 - 1.9e-05 23.8 0.0 4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EMD61144.1 - 0.00098 19.1 0.1 0.035 14.1 0.0 2.6 1 1 1 2 2 2 1 Ribosomal protein L9, C-terminal domain UCH PF00443.24 EMD61145.1 - 1.5e-42 145.6 0.0 2.9e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD61145.1 - 1.9e-13 50.4 0.0 2.9e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GFO_IDH_MocA PF01408.17 EMD61146.1 - 1.3e-12 48.2 0.0 3.9e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMD61146.1 - 0.016 14.9 0.0 0.016 14.9 0.0 2.3 3 0 0 3 3 3 0 Oxidoreductase family, C-terminal alpha/beta domain SFTA2 PF15210.1 EMD61148.1 - 0.058 12.9 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 Surfactant-associated protein 2 IBN_N PF03810.14 EMD61149.1 - 1.4e-14 53.7 0.5 1.6e-11 43.9 0.0 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 EMD61149.1 - 6.2e-07 28.3 0.7 1.9e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 EMD61149.1 - 0.00062 19.7 3.8 0.28 11.1 0.0 4.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF2435 PF10363.4 EMD61149.1 - 0.003 17.4 0.3 0.013 15.4 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) SDA1 PF05285.7 EMD61149.1 - 8.9 5.4 14.8 14 4.8 10.2 1.2 1 0 0 1 1 1 0 SDA1 FAT PF02259.18 EMD61151.1 - 1.1e-111 373.2 5.4 1.1e-111 373.2 3.7 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EMD61151.1 - 1.8e-61 207.6 0.5 3.6e-61 206.6 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EMD61151.1 - 8.9e-55 184.9 4.1 2.5e-52 177.0 0.1 5.9 7 0 0 7 7 7 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EMD61151.1 - 2e-41 140.0 0.0 2e-41 140.0 0.0 3.6 4 1 1 5 5 3 1 Rapamycin binding domain FATC PF02260.15 EMD61151.1 - 5e-17 61.0 0.0 1.3e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EMD61151.1 - 4.6e-14 52.4 17.9 0.0054 16.9 0.0 10.2 7 3 4 11 11 10 4 HEAT repeats HEAT PF02985.17 EMD61151.1 - 2.4e-11 42.7 22.4 0.1 12.7 0.0 11.3 12 0 0 12 12 10 3 HEAT repeat HEAT_EZ PF13513.1 EMD61151.1 - 2.7e-08 34.0 18.5 0.019 15.4 0.0 10.4 11 0 0 11 11 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMD61151.1 - 3e-07 30.7 0.0 1.5 9.2 0.0 6.7 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 EMD61151.1 - 5.4e-06 25.6 0.4 0.46 9.4 0.1 4.7 4 1 1 5 5 5 2 Protein of unknown function (DUF2454) TPR_16 PF13432.1 EMD61151.1 - 0.0013 19.3 2.3 0.62 10.8 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61151.1 - 0.0013 18.5 0.0 2.9 7.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1546 PF07571.8 EMD61151.1 - 0.037 14.1 0.1 7.2 6.7 0.0 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) TPR_7 PF13176.1 EMD61151.1 - 0.074 12.8 1.5 14 5.7 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2115 PF09888.4 EMD61151.1 - 0.075 13.1 0.2 0.28 11.2 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) TPR_1 PF00515.23 EMD61151.1 - 0.27 10.8 3.1 16 5.2 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61151.1 - 2.6 7.7 8.4 1.8 8.2 0.0 4.1 3 1 0 3 3 3 0 TPR repeat Apc3 PF12895.2 EMD61151.1 - 3.7 7.7 11.6 3 8.0 0.0 3.5 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EMD61151.1 - 5.4 7.1 10.3 3.6 7.7 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TauD PF02668.11 EMD61152.1 - 2.2e-37 129.1 0.0 3.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EMD61152.1 - 1.4e-05 25.4 0.2 0.0089 16.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.5 EMD61152.1 - 0.15 10.8 0.0 0.75 8.6 0.0 1.9 2 0 0 2 2 2 0 CsiD NADH_u_ox_C PF12853.2 EMD61153.1 - 1.8e-32 110.8 0.1 2.8e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EMD61153.1 - 1.3e-30 105.5 0.7 2.1e-30 104.7 0.5 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AAA_12 PF13087.1 EMD61154.1 - 7.4e-29 100.5 0.0 1.2e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMD61154.1 - 8e-24 84.5 0.0 1.5e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD61154.1 - 1.4e-10 40.7 0.1 8.4e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMD61154.1 - 5.1e-05 22.9 0.0 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EMD61154.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD61154.1 - 0.0046 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EMD61154.1 - 0.0047 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMD61154.1 - 0.005 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD61154.1 - 0.0059 16.7 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMD61154.1 - 0.016 14.1 0.3 0.037 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DNA_topoisoIV PF00521.15 EMD61154.1 - 0.018 13.8 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A AAA_16 PF13191.1 EMD61154.1 - 0.02 14.8 0.0 0.092 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EMD61154.1 - 0.071 12.8 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 EMD61154.1 - 0.072 12.3 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DnaB_C PF03796.10 EMD61154.1 - 0.087 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.13 EMD61154.1 - 0.26 10.7 0.1 14 5.1 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EMD61154.1 - 0.31 9.8 0.0 0.51 9.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Tfb2 PF03849.9 EMD61155.1 - 3.9e-129 430.4 0.0 5.1e-129 430.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EMD61155.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 EMD61156.1 - 5.2e-13 48.9 0.0 7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EMD61156.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) NB-ARC PF00931.17 EMD61158.1 - 5.7e-09 35.2 0.0 7.4e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EMD61158.1 - 1.3e-06 28.5 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD61158.1 - 8.8e-05 22.2 0.1 0.00082 19.0 0.1 2.2 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EMD61158.1 - 0.00052 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EMD61158.1 - 0.0068 16.4 2.1 0.11 12.4 1.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 EMD61158.1 - 0.065 12.3 0.0 0.19 10.8 0.0 1.9 1 1 0 1 1 1 0 KaiC AAA_25 PF13481.1 EMD61158.1 - 0.072 12.4 0.2 0.19 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD61158.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Patatin PF01734.17 EMD61159.1 - 4.2e-19 69.2 0.0 5.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Toxin-deaminase PF14424.1 EMD61159.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Pkinase PF00069.20 EMD61160.1 - 1.3e-09 37.5 0.0 5.4e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61160.1 - 2.6e-05 23.4 0.0 0.00016 20.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.24 EMD61161.1 - 2e-40 138.0 0.0 3.9e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD61161.1 - 9.8e-05 22.1 0.1 0.00057 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMD61161.1 - 0.00014 21.0 0.0 0.0005 19.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD61161.1 - 0.00039 20.5 0.1 0.018 15.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD61161.1 - 0.00044 20.2 1.6 0.012 15.5 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EMD61161.1 - 0.00098 19.0 0.1 0.0094 15.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EMD61161.1 - 0.0042 16.3 0.8 0.044 12.9 0.1 2.4 3 0 0 3 3 3 1 PhoH-like protein Mg_chelatase PF01078.16 EMD61161.1 - 0.0056 15.8 0.1 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMD61161.1 - 0.0074 16.1 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMD61161.1 - 0.0094 14.9 0.7 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMD61161.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EMD61161.1 - 0.023 14.1 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMD61161.1 - 0.036 13.4 1.2 0.3 10.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EMD61161.1 - 0.045 13.3 0.1 0.14 11.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD61161.1 - 0.069 12.2 0.5 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EMD61161.1 - 0.077 12.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMD61161.1 - 0.11 13.3 0.1 0.11 13.3 0.1 3.0 2 2 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EMD61161.1 - 0.34 10.4 3.3 0.51 9.8 0.0 2.5 2 2 0 3 3 3 0 AAA domain Vfa1 PF08432.5 EMD61161.1 - 6.2 6.8 8.1 12 5.8 5.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3419 PF11899.3 EMD61162.1 - 7.3e-150 498.9 0.0 1e-149 498.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EMD61162.1 - 9.6e-11 41.6 0.0 1e-09 38.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61162.1 - 2.9e-07 30.8 0.0 2e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61162.1 - 2.9e-07 30.1 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD61162.1 - 2.4e-06 27.5 0.1 0.0014 18.6 0.0 3.3 3 2 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61162.1 - 2.5e-06 28.0 0.0 3.3e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD61162.1 - 0.00032 21.1 0.0 0.039 14.4 0.0 3.8 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 EMD61162.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EMD61162.1 - 0.0082 15.2 0.0 0.039 13.0 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMD61162.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rer1 PF03248.8 EMD61163.1 - 3e-78 261.4 0.8 3.4e-78 261.2 0.6 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 EMD61164.1 - 6.3e-69 231.7 0.6 8.3e-69 231.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1258 PF06869.7 EMD61164.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Ferric_reduct PF01794.14 EMD61165.1 - 3.3e-15 56.2 11.9 3.3e-15 56.2 8.2 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMD61165.1 - 1.7e-09 37.5 0.0 4.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD61165.1 - 9.6e-08 32.0 0.0 0.019 14.9 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF1331 PF07048.6 EMD61166.1 - 0.099 12.1 0.5 0.16 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DSHCT PF08148.7 EMD61167.1 - 1.9e-60 203.1 0.6 3.8e-60 202.2 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EMD61167.1 - 1e-20 73.9 0.1 3.5e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61167.1 - 5e-07 29.4 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD61167.1 - 0.0048 16.7 0.3 0.28 11.0 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Syntaxin PF00804.20 EMD61167.1 - 0.027 14.6 0.6 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Syntaxin Swi3 PF07962.7 EMD61168.1 - 4.5e-30 103.1 0.1 7.3e-30 102.4 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TMEM247 PF15444.1 EMD61168.1 - 0.25 11.1 0.9 0.45 10.3 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 efThoc1 PF11957.3 EMD61169.1 - 1.8e-134 448.9 0.3 2.2e-134 448.6 0.2 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeobox PF00046.24 EMD61170.1 - 3.1e-17 61.9 3.2 5.2e-17 61.2 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD61170.1 - 0.013 15.2 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.8 EMD61170.1 - 0.015 14.9 1.6 0.024 14.2 1.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.8 EMD61170.1 - 0.16 11.5 4.3 0.25 10.9 3.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein MIF4G PF02854.14 EMD61173.1 - 2e-50 171.1 0.0 2e-50 171.1 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EMD61173.1 - 1.4e-16 60.1 0.3 1.4e-16 60.1 0.2 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4G1 DUF2823 PF11034.3 EMD61174.1 - 0.048 13.7 1.3 0.45 10.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2823) Chlorosome_CsmC PF11098.3 EMD61174.1 - 0.062 13.0 7.1 0.078 12.6 5.0 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C Amidase02_C PF12123.3 EMD61174.1 - 0.16 11.6 1.1 0.27 10.8 0.7 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Tape_meas_lam_C PF09718.5 EMD61174.1 - 0.31 10.9 2.5 13 5.8 0.2 2.1 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) adh_short PF00106.20 EMD61175.1 - 3.7e-27 95.2 0.1 4.9e-27 94.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD61175.1 - 2.1e-11 43.7 0.1 3.1e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD61175.1 - 5.4e-10 39.4 0.1 2.4e-09 37.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD61175.1 - 0.021 14.2 0.4 0.1 12.0 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMD61175.1 - 0.066 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ATP-grasp_2 PF08442.5 EMD61176.1 - 3.9e-77 258.1 0.4 6.6e-77 257.4 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EMD61176.1 - 1.7e-25 89.4 0.6 3.1e-25 88.5 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EMD61176.1 - 1.1e-09 37.9 0.2 2.7e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 EMD61176.1 - 0.0045 16.1 0.2 0.0083 15.2 0.2 1.4 1 0 0 1 1 1 1 Periplasmic binding protein GARS_A PF01071.14 EMD61176.1 - 0.0078 15.7 1.4 0.11 11.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EMD61176.1 - 0.097 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF3245 PF11595.3 EMD61177.1 - 4.8e-10 39.8 6.8 4.8e-10 39.8 4.7 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Thiolase_N PF00108.18 EMD61178.1 - 2.1e-80 269.4 0.7 2.7e-80 269.1 0.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD61178.1 - 8.4e-42 141.4 0.4 2.2e-41 140.1 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMD61178.1 - 0.0082 15.6 1.3 0.019 14.4 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NTF2 PF02136.15 EMD61179.1 - 3e-33 114.6 0.3 3.4e-33 114.5 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EMD61179.1 - 0.0074 16.4 0.0 0.0088 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EMD61179.1 - 0.073 13.4 0.0 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Epimerase PF01370.16 EMD61180.1 - 8.6e-20 71.1 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD61180.1 - 1.1e-13 50.4 0.0 1.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD61180.1 - 2.8e-10 39.5 0.0 7.9e-10 38.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMD61180.1 - 2.2e-06 27.6 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMD61180.1 - 3.5e-06 26.4 0.5 0.048 12.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EMD61180.1 - 3.5e-06 27.1 1.4 1.2e-05 25.3 1.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMD61180.1 - 0.00032 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMD61180.1 - 0.024 13.6 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMD61180.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Meth_synt_2 PF01717.13 EMD61181.1 - 9.8e-17 60.9 0.0 3.6e-11 42.6 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMD61181.1 - 8.1e-07 28.5 0.0 0.0004 19.7 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain CKS PF01111.14 EMD61181.1 - 0.017 14.9 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit GMC_oxred_C PF05199.8 EMD61182.1 - 3.5e-32 111.6 0.1 5.4e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMD61182.1 - 2.3e-30 105.8 0.0 1.2e-27 96.8 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EMD61182.1 - 0.0011 18.9 0.1 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD61182.1 - 0.0021 17.9 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD61182.1 - 0.0036 16.2 0.2 0.015 14.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD61182.1 - 0.019 15.0 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD61182.1 - 0.044 12.6 0.7 0.35 9.7 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 EMD61182.1 - 0.059 12.8 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TauD PF02668.11 EMD61183.1 - 3.8e-47 161.1 0.0 4.9e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EMD61184.1 - 1.3e-20 73.4 18.3 1.7e-20 73.0 12.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Varsurf_PPLC PF03490.8 EMD61184.1 - 0.055 13.1 0.4 0.28 10.8 0.2 2.0 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Aldo_ket_red PF00248.16 EMD61185.1 - 2.4e-69 233.2 0.0 2.8e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 EMD61186.1 - 9.6e-16 57.9 0.1 5.6e-07 29.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD61186.1 - 5.2e-09 36.3 0.2 0.0025 18.2 0.0 4.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD61186.1 - 2e-08 33.6 0.1 0.22 11.3 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EMD61186.1 - 2.5e-08 33.3 0.2 0.19 12.0 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EMD61186.1 - 3.8e-08 33.3 0.5 0.012 15.8 0.0 5.2 2 1 4 6 6 6 4 Ankyrin repeats (many copies) CorA PF01544.13 EMD61186.1 - 1.7e-05 24.0 0.0 3.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CASP_C PF08172.7 EMD61186.1 - 0.0046 16.0 0.4 0.0074 15.3 0.3 1.2 1 0 0 1 1 1 1 CASP C terminal AATase PF07247.7 EMD61187.1 - 1.7e-28 99.4 0.0 2.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMD61187.1 - 2.2e-07 30.0 0.5 1.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 EMD61187.1 - 0.048 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1996 PF09362.5 EMD61188.1 - 5.9e-91 304.3 0.7 7.3e-91 303.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Stk19 PF10494.4 EMD61189.1 - 0.089 12.1 0.3 0.16 11.3 0.1 1.5 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 zf-C2H2_jaz PF12171.3 EMD61190.1 - 8.1e-05 22.6 0.7 0.00013 22.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD61190.1 - 0.00076 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMD61190.1 - 0.0053 17.0 0.4 0.0053 17.0 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD61190.1 - 0.19 12.1 0.3 0.19 12.1 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1691 PF07950.6 EMD61191.1 - 4.1e-38 129.6 6.3 5.8e-23 80.9 1.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) TTL PF03133.10 EMD61192.1 - 1.1e-45 155.8 0.0 1.1e-28 99.9 0.0 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family zf-primase PF09329.6 EMD61192.1 - 3.7e-17 61.6 1.2 6.2e-17 60.9 0.8 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EMD61192.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 EMD61193.1 - 3.3e-91 305.6 3.7 4.1e-91 305.3 2.6 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Selenoprotein_S PF06936.6 EMD61193.1 - 0.005 16.4 0.7 0.0096 15.4 0.5 1.4 1 0 0 1 1 1 1 Selenoprotein S (SelS) DASH_Duo1 PF08651.5 EMD61195.1 - 5.5e-30 102.7 3.6 8.3e-30 102.1 2.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EMD61195.1 - 0.0034 16.9 14.5 0.0034 16.9 10.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF745) Dna2 PF08696.6 EMD61195.1 - 0.065 12.5 0.8 0.089 12.0 0.6 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3407 PF11887.3 EMD61195.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) BRF1 PF07741.8 EMD61195.1 - 0.68 10.1 8.3 5.1 7.3 1.8 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Macoilin PF09726.4 EMD61195.1 - 1.8 6.7 12.3 2.3 6.3 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 3HCDH_N PF02737.13 EMD61195.1 - 6.9 6.2 11.1 0.17 11.4 1.2 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GalKase_gal_bdg PF10509.4 EMD61196.1 - 3.1e-20 71.1 0.0 6e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EMD61196.1 - 4.1e-15 55.5 1.7 2.4e-14 53.1 1.5 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMD61196.1 - 3.1e-13 49.7 0.0 7.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Zn_clus PF00172.13 EMD61198.1 - 4.7e-08 32.8 9.3 1.1e-07 31.6 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L13e PF01294.13 EMD61199.1 - 1.3e-67 226.7 4.8 1.9e-67 226.2 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e LRR_4 PF12799.2 EMD61200.1 - 1.6e-39 132.8 31.9 1.4e-06 27.8 0.5 9.4 6 2 4 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD61200.1 - 2.1e-31 107.4 33.1 1.4e-06 27.9 0.6 8.6 6 3 4 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 EMD61200.1 - 8.7e-17 58.5 29.1 0.5 10.5 0.0 15.7 15 2 2 17 17 17 5 Leucine Rich Repeat LRR_7 PF13504.1 EMD61200.1 - 2.6e-10 38.7 39.4 1.4 9.4 0.1 14.2 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 EMD61200.1 - 1e-06 28.1 34.1 0.33 11.1 0.0 12.6 12 3 2 14 14 14 2 Leucine Rich repeat LRR_9 PF14580.1 EMD61200.1 - 0.00027 20.5 8.8 0.094 12.2 0.1 4.7 2 2 3 5 5 5 2 Leucine-rich repeat bZIP_1 PF00170.16 EMD61201.1 - 0.0091 15.9 7.7 0.55 10.2 0.6 3.3 2 1 1 3 3 3 2 bZIP transcription factor HALZ PF02183.13 EMD61201.1 - 0.082 12.6 7.9 0.65 9.7 1.1 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EMD61201.1 - 2.9 7.6 6.3 2.1 8.1 1.4 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 EMD61201.1 - 4.7 7.5 14.9 42 4.5 10.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FliD_N PF02465.13 EMD61202.1 - 0.003 17.9 0.7 0.007 16.7 0.5 1.6 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus DUF2296 PF10058.4 EMD61204.1 - 8.5e-20 70.2 0.1 1.6e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) AA_permease PF00324.16 EMD61204.1 - 0.11 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease DUF4463 PF14703.1 EMD61204.1 - 0.16 12.5 1.7 0.18 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF605 PF04652.11 EMD61204.1 - 1.6 8.0 18.0 2.3 7.5 12.5 1.2 1 0 0 1 1 1 0 Vta1 like Complex1_LYR PF05347.10 EMD61205.1 - 3.4e-07 29.9 0.3 5.4e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD61205.1 - 6.4e-05 23.0 0.5 0.00011 22.3 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF2353 PF09789.4 EMD61205.1 - 0.057 12.6 0.5 0.062 12.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF924 PF06041.6 EMD61205.1 - 0.093 12.4 0.2 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) RRM_5 PF13893.1 EMD61206.1 - 3.8e-09 36.2 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD61206.1 - 2.9e-08 33.2 0.0 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD61206.1 - 0.00036 20.4 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD61206.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMD61206.1 - 0.038 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Sterol_MT_C PF08498.5 EMD61207.1 - 3.7e-30 103.6 0.2 6.2e-30 102.9 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EMD61207.1 - 9.1e-21 74.1 0.0 1.7e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61207.1 - 1.1e-16 60.8 0.0 1.5e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD61207.1 - 2.2e-14 53.5 0.0 3.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD61207.1 - 5e-14 52.4 0.0 9.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD61207.1 - 3.6e-13 49.2 0.1 5.2e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMD61207.1 - 6.4e-10 38.5 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMD61207.1 - 7.9e-10 39.1 0.0 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61207.1 - 8.3e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD61207.1 - 4.1e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMD61207.1 - 8.4e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMD61207.1 - 8.9e-05 21.9 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EMD61207.1 - 0.00016 20.2 0.0 0.00023 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EMD61207.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EMD61207.1 - 0.00058 19.4 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 EMD61207.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EMD61207.1 - 0.0026 16.9 0.2 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EMD61207.1 - 0.0072 15.5 0.2 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EMD61207.1 - 0.0074 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMD61207.1 - 0.016 14.4 0.2 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 EMD61207.1 - 0.047 14.5 0.0 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EMD61207.1 - 0.055 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF972 PF06156.8 EMD61207.1 - 0.11 12.8 0.3 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Transket_pyr PF02779.19 EMD61208.1 - 7.3e-49 165.6 0.0 9.6e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMD61208.1 - 8.5e-34 116.1 0.0 2.2e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldo_ket_red PF00248.16 EMD61211.1 - 1.6e-58 197.7 0.0 2e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldedh PF00171.17 EMD61212.1 - 1.1e-158 528.4 0.1 1.2e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 EMD61213.1 - 1.7e-49 168.6 0.0 2.3e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD61213.1 - 5.5e-38 130.5 0.0 8.5e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD61213.1 - 3.4e-06 26.2 0.0 0.00019 20.4 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD61213.1 - 2.5e-05 23.3 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD61213.1 - 4.3e-05 23.4 0.0 0.00017 21.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD61213.1 - 0.00014 20.8 0.0 0.085 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EMD61213.1 - 0.0023 18.2 0.1 0.18 12.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD61213.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMD61213.1 - 0.03 14.1 0.0 0.079 12.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD61213.1 - 0.081 11.9 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EMD61213.1 - 0.14 11.2 0.0 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EMD61213.1 - 0.18 10.2 0.0 0.33 9.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein WD40 PF00400.27 EMD61216.1 - 4.1e-86 280.0 27.4 1.1e-14 53.6 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 EMD61216.1 - 5.5e-14 52.1 1.4 2.8e-12 46.6 1.0 2.5 1 1 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD61216.1 - 9.9e-11 40.4 16.0 0.23 9.5 0.1 6.1 1 1 5 6 6 6 6 Nucleoporin Nup120/160 BLUF PF04940.7 EMD61216.1 - 1.8e-06 27.5 0.0 27 4.5 0.0 5.8 5 0 0 5 5 5 0 Sensors of blue-light using FAD SRP9-21 PF05486.7 EMD61216.1 - 2.7e-05 23.8 0.1 82 3.0 0.0 6.7 6 1 0 6 6 6 0 Signal recognition particle 9 kDa protein (SRP9) CDtoxinA PF03498.9 EMD61216.1 - 0.00046 19.5 0.0 0.93 8.8 0.0 3.4 1 1 3 4 4 4 2 Cytolethal distending toxin A/C family DUF3312 PF11768.3 EMD61216.1 - 0.00049 18.4 1.0 0.61 8.2 0.0 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF3312) UPF0079 PF02367.12 EMD61216.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EMD61216.1 - 0.0086 16.2 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EMD61216.1 - 0.047 13.6 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain YtxH PF12732.2 EMD61217.1 - 0.039 14.3 4.5 1.2 9.5 0.5 2.8 2 1 1 3 3 3 0 YtxH-like protein Baculo_PEP_C PF04513.7 EMD61217.1 - 0.043 13.6 2.0 1.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mistic PF11458.3 EMD61217.1 - 0.078 13.3 1.1 0.37 11.2 0.5 2.2 1 1 1 2 2 2 0 Membrane-integrating protein Mistic DUF948 PF06103.6 EMD61217.1 - 0.089 12.6 3.0 3.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EMD61217.1 - 0.14 11.9 1.1 1.4 8.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PMEI PF04043.10 EMD61217.1 - 0.17 11.8 5.0 0.038 13.8 0.7 2.0 2 1 1 3 3 3 0 Plant invertase/pectin methylesterase inhibitor PilJ PF13675.1 EMD61217.1 - 0.2 11.9 2.4 6.3 7.1 0.0 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Muted PF14942.1 EMD61217.1 - 0.52 10.1 5.5 0.46 10.3 1.4 2.2 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Syntaxin_2 PF14523.1 EMD61217.1 - 1.4 9.0 5.0 6.5 6.8 0.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein Reo_sigmaC PF04582.7 EMD61217.1 - 1.5 7.9 5.6 0.51 9.4 0.2 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein HET PF06985.6 EMD61219.1 - 5.2e-30 104.4 0.0 3.9e-29 101.5 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dabb PF07876.7 EMD61221.1 - 3.6e-11 43.3 0.0 1.6e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3349 PF11829.3 EMD61223.1 - 0.058 13.8 0.2 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) XPG_I_2 PF12813.2 EMD61224.1 - 4.9e-43 147.4 4.0 5.3e-43 147.2 0.3 2.2 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.13 EMD61224.1 - 0.00035 20.5 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMD61224.1 - 0.0017 18.5 0.0 0.0068 16.6 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain PGM_PMM_I PF02878.11 EMD61225.1 - 2e-33 114.8 0.0 2.9e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMD61225.1 - 1.5e-25 89.4 0.0 2.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMD61225.1 - 9.7e-15 54.7 0.1 2.2e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMD61225.1 - 2.6e-11 43.3 0.8 5.4e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Oxysterol_BP PF01237.13 EMD61226.1 - 4e-93 311.7 4.3 4.9e-93 311.4 3.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein BOP1NT PF08145.7 EMD61226.1 - 0.012 15.4 1.4 0.022 14.4 1.0 1.5 1 0 0 1 1 1 0 BOP1NT (NUC169) domain BPL_N PF09825.4 EMD61227.1 - 9.7e-141 468.8 0.0 1.3e-140 468.3 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EMD61227.1 - 5.3e-17 61.9 0.0 1.4e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EMD61227.1 - 0.00018 21.1 0.0 0.00044 19.8 0.0 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain MRP-L28 PF09812.4 EMD61228.1 - 1.6e-06 28.0 0.2 2.8e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EMD61229.1 - 6.4e-48 162.2 0.0 7.4e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD61229.1 - 5.8e-17 62.2 0.0 1.5e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMD61229.1 - 8.4e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD61229.1 - 0.0083 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMD61229.1 - 0.011 14.8 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EMD61229.1 - 0.034 13.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EMD61229.1 - 0.089 12.7 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EMD61229.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1517 PF07466.6 EMD61230.1 - 0.015 14.3 1.1 0.018 14.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Baculo_11_kDa PF06143.6 EMD61230.1 - 0.036 13.4 3.9 0.05 12.9 2.7 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Zn_peptidase PF04228.8 EMD61230.1 - 0.087 12.0 1.8 0.088 12.0 1.3 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Herpes_gE PF02480.11 EMD61230.1 - 0.28 9.4 0.9 0.27 9.4 0.6 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NST1 PF13945.1 EMD61231.1 - 1.6e-61 207.6 1.3 1.6e-61 207.6 0.9 5.3 4 1 1 5 5 5 1 Salt tolerance down-regulator DUF2973 PF11189.3 EMD61231.1 - 6.9 6.5 5.0 5.5 6.8 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) PGM_PMM_I PF02878.11 EMD61232.1 - 3.1e-20 72.0 0.0 2.5e-09 36.7 0.0 3.0 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMD61232.1 - 2.7e-16 59.7 1.2 1.7e-14 53.9 0.0 3.6 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMD61232.1 - 4.4e-10 39.4 2.1 6.3e-09 35.7 0.3 3.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EMD61232.1 - 0.00027 20.9 0.1 0.00062 19.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Flavodoxin_3 PF12641.2 EMD61232.1 - 0.13 11.6 0.0 0.51 9.7 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain DUF221 PF02714.10 EMD61233.1 - 7.3e-92 307.6 20.9 1.2e-91 306.9 14.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD61233.1 - 1.7e-38 131.6 2.6 1.7e-38 131.6 1.8 2.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMD61233.1 - 9.2e-15 54.9 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Prefoldin PF02996.12 EMD61233.1 - 0.34 10.5 0.4 0.9 9.1 0.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit DAGK_cat PF00781.19 EMD61235.1 - 8.5e-07 28.4 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ETF_alpha PF00766.14 EMD61235.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Asp PF00026.18 EMD61236.1 - 2e-37 129.1 0.2 2.4e-37 128.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMD61236.1 - 7.7e-05 22.7 0.1 0.00018 21.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.18 EMD61237.1 - 7.1e-48 163.4 0.5 8.2e-48 163.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF3443 PF11925.3 EMD61237.1 - 0.0076 14.9 0.9 0.12 11.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3443) Asp_protease_2 PF13650.1 EMD61237.1 - 0.06 13.8 0.1 1.4 9.4 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Peptidase_S49_N PF08496.5 EMD61239.1 - 0.42 10.3 2.4 0.66 9.7 1.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Asp PF00026.18 EMD61240.1 - 4.1e-08 32.8 0.1 6.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ifi-6-16 PF06140.8 EMD61241.1 - 0.43 10.4 15.1 1.2 8.9 10.5 1.8 1 0 0 1 1 1 0 Interferon-induced 6-16 family Piwi PF02171.12 EMD61242.1 - 6.2e-71 238.8 0.0 1.5e-70 237.5 0.0 1.6 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMD61242.1 - 3.3e-16 58.8 0.0 8.7e-16 57.4 0.0 1.7 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 EMD61242.1 - 6.5e-16 57.4 0.2 1.5e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Acetyltransf_3 PF13302.1 EMD61243.1 - 2.5e-19 69.8 0.0 3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD61243.1 - 2.3e-08 33.9 0.3 4.3e-08 33.0 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMD61243.1 - 5.7e-05 22.7 0.1 0.00015 21.4 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 EMD61243.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD61243.1 - 0.00049 20.2 0.3 0.00098 19.2 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMD61243.1 - 0.0056 16.6 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.10 EMD61244.1 - 2.6e-47 161.4 25.7 2.7e-19 69.0 2.5 3.9 1 1 2 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin E1-E2_ATPase PF00122.15 EMD61245.1 - 9.6e-48 162.2 7.7 9.6e-48 162.2 5.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMD61245.1 - 4.4e-23 82.8 0.1 9.3e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD61245.1 - 1.2e-13 51.6 0.0 2.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD61245.1 - 2.2e-06 27.4 0.2 0.00011 21.8 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMD61245.1 - 9.7e-06 25.6 0.7 2.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF3168 PF11367.3 EMD61245.1 - 0.027 14.6 0.1 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) ECH PF00378.15 EMD61247.1 - 1.4e-64 217.5 0.3 1.7e-64 217.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EMD61247.1 - 0.11 12.5 0.3 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 EMD61248.1 - 3.4e-90 302.4 0.0 6.3e-90 301.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD61248.1 - 8.8e-05 23.3 0.0 0.00034 21.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ferric_reduct PF01794.14 EMD61248.1 - 1.1 9.3 12.5 4 7.5 8.7 2.0 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Glycos_transf_2 PF00535.21 EMD61249.1 - 1.6e-33 115.7 0.0 1.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMD61249.1 - 5.1e-13 49.3 0.0 7.1e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMD61249.1 - 1.7e-08 33.8 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMD61249.1 - 4e-05 22.9 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EMD61249.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EMD61249.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hydrolase_like PF13242.1 EMD61250.1 - 8.6e-07 28.5 0.0 2.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EMD61250.1 - 3.4e-06 27.4 0.0 0.077 13.2 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Nop14 PF04147.7 EMD61251.1 - 0.64 7.8 17.0 0.45 8.3 4.1 2.0 2 0 0 2 2 2 0 Nop14-like family Surp PF01805.15 EMD61252.1 - 3.6e-14 52.1 0.0 6.9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Surp module TPR_19 PF14559.1 EMD61254.1 - 6.2e-13 48.8 4.5 3e-08 33.8 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61254.1 - 4.8e-09 36.6 9.3 1.8e-05 25.2 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61254.1 - 1.4e-08 34.6 7.8 0.054 14.1 0.6 5.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMD61254.1 - 7.4e-06 26.0 0.1 0.17 12.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EMD61254.1 - 6.6e-05 22.2 0.3 9.5e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 EMD61254.1 - 0.0003 20.6 1.6 0.0099 15.8 0.2 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD61254.1 - 0.00072 19.2 1.9 18 5.5 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMD61254.1 - 0.0011 18.8 3.5 1.5 8.7 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EMD61254.1 - 0.003 17.5 4.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61254.1 - 0.0032 17.5 0.2 0.032 14.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61254.1 - 0.015 14.9 0.1 0.015 14.9 0.1 3.5 4 1 0 4 4 4 0 TPR repeat YfiO PF13525.1 EMD61254.1 - 0.057 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_10 PF13374.1 EMD61254.1 - 0.071 13.0 2.4 1.1 9.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMD61254.1 - 0.079 13.0 4.9 0.75 9.9 0.1 3.6 3 1 2 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EMD61254.1 - 0.19 10.4 0.3 0.76 8.4 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.12 EMD61254.1 - 2.6 8.3 9.6 1.5 9.1 1.7 3.1 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPP_enzyme_N PF02776.13 EMD61255.1 - 1.9e-57 193.5 0.1 3.9e-57 192.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMD61255.1 - 3e-47 160.0 0.0 3.6e-46 156.5 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD61255.1 - 1.5e-39 134.9 0.8 8e-39 132.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EMD61255.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Glyco_hydro_16 PF00722.16 EMD61256.1 - 9.7e-39 132.5 5.0 9.7e-39 132.5 3.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Mucin PF01456.12 EMD61256.1 - 0.062 13.0 13.9 0.13 12.0 9.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2201_N PF13203.1 EMD61256.1 - 1.1 8.3 5.2 1.9 7.5 3.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pkinase PF00069.20 EMD61257.1 - 6.9e-39 133.5 0.2 4.1e-24 85.1 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61257.1 - 2e-14 53.3 0.3 3.8e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SP_C-Propep PF08999.5 EMD61258.1 - 0.24 10.9 4.4 0.25 10.8 2.7 1.5 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tropomyosin PF00261.15 EMD61259.1 - 0.0003 19.9 33.2 0.0003 19.9 23.0 4.5 3 1 1 5 5 5 2 Tropomyosin DivIVA PF05103.8 EMD61259.1 - 0.00039 20.4 12.8 0.00039 20.4 8.9 6.8 4 1 3 7 7 7 1 DivIVA protein Phage_GP20 PF06810.6 EMD61259.1 - 0.001 18.5 9.1 0.001 18.5 6.3 5.6 2 1 3 5 5 5 2 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EMD61259.1 - 0.0052 16.0 31.5 0.25 10.4 3.4 4.1 2 1 2 4 4 4 3 Reovirus sigma C capsid protein Sipho_Gp157 PF05565.6 EMD61259.1 - 0.0065 16.0 9.0 0.0065 16.0 6.2 5.0 2 1 3 5 5 5 1 Siphovirus Gp157 FlxA PF14282.1 EMD61259.1 - 0.0096 15.8 13.1 0.0096 15.8 9.1 6.5 3 1 3 6 6 6 1 FlxA-like protein Fib_alpha PF08702.5 EMD61259.1 - 0.012 15.7 48.2 2.6 8.1 7.7 4.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EMD61259.1 - 0.059 12.5 71.7 0.5 9.5 12.2 4.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding EzrA PF06160.7 EMD61259.1 - 0.088 10.9 63.8 0.08 11.1 2.1 4.2 2 1 2 4 4 4 0 Septation ring formation regulator, EzrA IncA PF04156.9 EMD61259.1 - 0.15 11.6 83.6 0.84 9.1 16.4 5.3 2 1 2 4 4 4 0 IncA protein HOOK PF05622.7 EMD61259.1 - 0.63 7.7 67.8 0.092 10.5 28.0 3.3 2 1 1 3 3 3 0 HOOK protein APG6 PF04111.7 EMD61259.1 - 1.2 8.0 83.0 0.61 9.0 7.0 4.8 2 1 3 5 5 5 0 Autophagy protein Apg6 WEMBL PF05701.6 EMD61259.1 - 1.3 7.4 88.5 0.13 10.6 45.2 3.9 3 1 0 3 3 3 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EMD61259.1 - 2.3 6.8 70.7 0.015 14.0 4.0 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.1 EMD61259.1 - 2.7 6.3 64.0 0.25 9.7 16.5 3.6 2 1 1 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.7 EMD61259.1 - 4 7.1 78.2 0.43 10.3 16.3 6.1 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EMD61259.1 - 6.2 6.6 78.5 0.37 10.6 3.5 5.8 5 1 1 6 6 5 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EMD61259.1 - 7.3 6.4 93.9 2.2 8.0 15.9 5.2 3 2 1 4 4 4 0 Tropomyosin like DUF4201 PF13870.1 EMD61259.1 - 7.6 5.9 66.7 1.7 8.0 17.3 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) DnaJ PF00226.26 EMD61260.1 - 2.2e-21 75.3 0.3 2.2e-21 75.3 0.2 2.5 3 0 0 3 3 3 1 DnaJ domain Trm56 PF01994.11 EMD61260.1 - 0.073 12.8 0.1 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Usp PF00582.21 EMD61261.1 - 3.6e-18 66.1 0.0 1.1e-17 64.5 0.0 1.9 1 0 0 1 1 1 1 Universal stress protein family ABA_GPCR PF12430.3 EMD61262.1 - 3.3e-55 186.2 5.3 3.9e-55 186.0 0.4 2.3 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EMD61262.1 - 2.2e-18 66.0 0.4 5.9e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) RINGv PF12906.2 EMD61264.1 - 9e-07 28.8 6.9 1.8e-06 27.8 4.8 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EMD61264.1 - 4.7e-06 26.4 3.6 1.1e-05 25.3 2.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMD61264.1 - 0.00065 19.4 4.0 0.0011 18.7 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain COPI_C PF06957.6 EMD61264.1 - 0.13 10.8 4.6 0.19 10.2 3.2 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zf-C3HC4_3 PF13920.1 EMD61264.1 - 0.61 9.8 2.9 1.1 9.0 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NRDE PF05742.7 EMD61266.1 - 2.4e-48 164.8 0.0 4.1e-48 164.0 0.0 1.3 1 1 0 1 1 1 1 NRDE protein Tic20 PF09685.5 EMD61267.1 - 1.1e-06 28.5 1.6 1.4e-06 28.2 1.1 1.2 1 0 0 1 1 1 1 Tic20-like protein Cytochrom_C550 PF14495.1 EMD61269.1 - 0.0026 17.2 1.3 0.0031 16.9 0.9 1.3 1 1 0 1 1 1 1 Cytochrome c-550 domain zf-CCHC_4 PF14392.1 EMD61269.1 - 0.04 13.5 0.6 0.04 13.5 0.4 1.5 2 0 0 2 2 2 0 Zinc knuckle Cytochrome_C554 PF13435.1 EMD61269.1 - 0.041 13.9 3.8 0.052 13.6 2.7 1.3 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_C_2 PF01322.15 EMD61269.1 - 0.056 13.9 1.6 0.068 13.7 1.1 1.1 1 0 0 1 1 1 0 Cytochrome C' DUF972 PF06156.8 EMD61269.1 - 0.066 13.5 1.5 0.073 13.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pep_M12B_propep PF01562.14 EMD61269.1 - 0.092 12.5 0.1 0.1 12.3 0.1 1.0 1 0 0 1 1 1 0 Reprolysin family propeptide DUF773 PF05600.7 EMD61269.1 - 0.6 8.8 5.8 0.7 8.5 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Siah-Interact_N PF09032.6 EMD61269.1 - 0.76 9.8 11.9 2.3 8.3 8.3 1.8 1 1 0 1 1 1 0 Siah interacting protein, N terminal Phage_prot_Gp6 PF05133.9 EMD61269.1 - 0.85 8.1 3.3 0.9 8.0 2.3 1.0 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Hepcidin PF06446.7 EMD61269.1 - 1.5 9.2 9.2 0.18 12.2 2.6 1.9 1 1 1 2 2 2 0 Hepcidin zf-C4pol PF14260.1 EMD61269.1 - 2.1 8.4 7.8 4.7 7.2 5.4 1.7 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta MAGE_N PF12440.3 EMD61269.1 - 4 7.8 13.6 7.7 6.8 9.4 1.5 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal Aminotran_5 PF00266.14 EMD61271.1 - 1.7e-12 46.7 0.0 2.1e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMD61271.1 - 1.8e-05 23.8 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF59 PF01883.14 EMD61271.1 - 0.056 13.4 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF59 SLA_LP_auto_ag PF05889.8 EMD61271.1 - 0.066 11.6 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ank_2 PF12796.2 EMD61272.1 - 3.5e-27 94.5 4.8 8.8e-11 41.9 0.5 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMD61272.1 - 6.3e-23 79.3 4.1 8.5e-06 25.3 0.2 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EMD61272.1 - 6.3e-18 64.4 2.1 2e-06 27.8 0.3 5.3 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD61272.1 - 1.1e-17 63.9 4.8 0.0001 22.6 0.0 6.1 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD61272.1 - 1.9e-15 55.4 0.9 0.00014 21.7 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat DUF1828 PF08861.5 EMD61272.1 - 0.074 12.7 0.2 3.9 7.1 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function DUF1828 Sugar_tr PF00083.19 EMD61273.1 - 1.5e-81 274.2 27.8 1.8e-81 274.0 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61273.1 - 7.4e-16 57.7 33.9 7.4e-16 57.7 23.5 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EMD61274.1 - 1.1e-11 44.1 0.1 1.8e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.21 EMD61275.1 - 1.9e-132 442.2 4.7 2.3e-132 441.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD61275.1 - 1.6e-05 24.7 0.7 0.00012 21.8 0.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_39 PF01229.12 EMD61276.1 - 0.0039 15.6 0.1 0.0057 15.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 PADR1 PF08063.7 EMD61277.1 - 0.16 11.4 0.5 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 PADR1 (NUC008) domain DUF4163 PF13739.1 EMD61278.1 - 0.059 14.1 1.0 0.09 13.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) DUF3390 PF11870.3 EMD61279.1 - 0.061 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF2375 PF09558.5 EMD61279.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) bZIP_1 PF00170.16 EMD61281.1 - 0.0012 18.7 10.7 0.0012 18.7 7.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor GCN5L1 PF06320.8 EMD61281.1 - 0.094 12.5 4.0 0.16 11.7 2.8 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) bZIP_Maf PF03131.12 EMD61281.1 - 0.23 11.7 8.0 0.55 10.5 5.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor SMN PF06003.7 EMD61281.1 - 9.4 5.2 10.4 9.8 5.1 0.6 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) HET PF06985.6 EMD61282.1 - 9.9e-15 54.9 0.6 1.1e-14 54.8 0.4 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tannase PF07519.6 EMD61284.1 - 1e-105 354.1 0.5 1.2e-104 350.7 0.4 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EMD61284.1 - 7.1e-06 25.8 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD61284.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD61284.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 EMD61285.1 - 3.1e-20 72.7 0.0 4.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD61285.1 - 6.6e-10 38.9 0.0 9.4e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD61285.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 EMD61287.1 - 2.8e-07 30.8 0.0 4.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 EMD61288.1 - 4.5e-127 409.9 52.6 1.8e-14 52.9 0.2 9.7 9 0 0 9 9 9 9 WD domain, G-beta repeat NACHT PF05729.7 EMD61288.1 - 5.6e-26 91.1 0.1 9.8e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD61288.1 - 9.8e-22 77.6 10.9 1.6e-20 73.7 4.8 3.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD61288.1 - 2.5e-15 55.6 28.7 0.00097 17.3 4.1 7.6 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD61288.1 - 4.8e-08 32.1 21.7 0.0022 16.7 0.3 6.0 1 1 4 5 5 5 5 Nup133 N terminal like AAA_16 PF13191.1 EMD61288.1 - 1.4e-05 25.1 0.3 6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain CDtoxinA PF03498.9 EMD61288.1 - 6.8e-05 22.2 0.1 13 5.1 0.0 4.9 2 1 1 4 4 4 1 Cytolethal distending toxin A/C family AAA_22 PF13401.1 EMD61288.1 - 0.0028 17.7 0.0 0.018 15.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD61288.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EMD61288.1 - 0.056 13.6 0.0 0.26 11.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NYD-SP28_assoc PF14775.1 EMD61288.1 - 2.3 8.0 7.7 69 3.2 0.0 5.6 7 0 0 7 7 7 0 Sperm tail C-terminal domain Peptidase_M28 PF04389.12 EMD61289.1 - 2e-35 122.1 0.1 2.7e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMD61289.1 - 3.2e-11 42.8 0.0 6.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMD61289.1 - 4.4e-07 29.5 0.1 8.5e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3605 PF12239.3 EMD61290.1 - 1.3e-51 174.6 0.6 1.5e-51 174.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CPL PF08144.6 EMD61291.1 - 3.9e-07 30.0 0.0 3.9e-07 30.0 0.0 2.8 4 0 0 4 4 4 1 CPL (NUC119) domain DNA_RNApol_7kD PF03604.8 EMD61292.1 - 3.3e-17 61.6 5.3 4.2e-17 61.2 3.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EMD61292.1 - 0.0099 15.5 0.2 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMD61292.1 - 0.012 15.4 0.6 0.015 15.0 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EMD61292.1 - 0.018 14.8 1.0 0.66 9.8 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF951 PF06107.6 EMD61292.1 - 0.023 14.2 0.6 0.92 9.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF2318 PF10080.4 EMD61292.1 - 0.084 12.6 0.3 0.092 12.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-ISL3 PF14690.1 EMD61292.1 - 0.1 12.6 0.6 0.1 12.6 0.4 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.5 EMD61292.1 - 0.1 12.5 2.7 0.19 11.6 1.9 1.5 1 1 0 1 1 1 0 Zinc ribbon domain DUF2082 PF09855.4 EMD61292.1 - 0.11 12.3 0.3 0.18 11.6 0.2 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TFIIS_C PF01096.13 EMD61292.1 - 0.11 12.1 4.1 3.3 7.4 0.1 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 EMD61292.1 - 0.16 11.9 1.1 9.9 6.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 EMD61292.1 - 0.19 11.2 2.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_ribbon_recom PF13408.1 EMD61292.1 - 0.2 11.9 2.6 1.4 9.2 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain LRV_FeS PF05484.6 EMD61292.1 - 0.31 10.6 2.1 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 LRV protein FeS4 cluster zinc_ribbon_4 PF13717.1 EMD61292.1 - 1.3 8.7 5.1 0.59 9.8 0.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.1 EMD61292.1 - 1.7 8.3 4.1 2 8.1 0.3 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain zinc_ribbon_5 PF13719.1 EMD61292.1 - 1.9 8.1 5.5 0.69 9.5 0.5 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 EMD61293.1 - 1.8e-57 194.4 0.1 1.1e-39 136.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61293.1 - 6.4e-26 90.9 0.3 6.2e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMD61293.1 - 0.00027 20.7 0.1 0.018 14.7 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD61293.1 - 0.00048 19.2 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD61293.1 - 0.00087 18.3 0.5 0.0019 17.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EMD61293.1 - 0.0099 16.3 0.1 0.024 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.17 EMD61293.1 - 0.045 13.0 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EMD61293.1 - 0.055 12.2 0.1 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NPR3 PF03666.8 EMD61294.1 - 0.16 10.4 0.1 0.17 10.4 0.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Filament PF00038.16 EMD61295.1 - 0.0045 16.4 38.0 0.0045 16.4 26.4 4.7 3 2 0 3 3 3 2 Intermediate filament protein KNOX2 PF03791.8 EMD61295.1 - 1.6 8.0 6.6 0.61 9.3 0.1 3.3 3 0 0 3 3 3 0 KNOX2 domain Mod_r PF07200.8 EMD61297.1 - 2.3e-11 43.8 2.4 1e-10 41.6 1.6 1.9 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3263 PF11662.3 EMD61297.1 - 0.001 18.4 1.5 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3263) DUF641 PF04859.7 EMD61297.1 - 0.017 14.9 0.3 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) WD40 PF00400.27 EMD61298.1 - 2.3e-46 154.0 20.2 1.2e-10 40.8 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMD61298.1 - 3.8e-07 29.9 18.4 0.021 14.5 0.5 5.2 2 2 4 6 6 6 3 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 EMD61298.1 - 0.013 15.6 0.7 1.3 9.3 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 EMD61298.1 - 0.026 14.6 1.2 0.64 10.2 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain IKI3 PF04762.7 EMD61298.1 - 0.53 8.0 7.2 0.32 8.7 0.5 2.0 2 0 0 2 2 2 0 IKI3 family CBP PF12192.3 EMD61299.1 - 1.8e-05 24.5 4.6 3.8e-05 23.5 3.2 1.6 1 0 0 1 1 1 1 Fungal calcium binding protein GIY-YIG PF01541.19 EMD61300.1 - 0.0018 18.6 1.8 0.0029 17.9 0.1 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain CBM_19 PF03427.8 EMD61301.1 - 1.5e-06 27.8 5.3 1.5e-06 27.8 3.7 2.8 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) Chitin_bind_3 PF03067.10 EMD61301.1 - 8.1e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Chitin binding domain SNF5 PF04855.7 EMD61302.1 - 5.4e-80 268.3 0.0 7.3e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EMD61302.1 - 0.00019 20.6 3.2 0.00043 19.5 2.2 1.6 1 0 0 1 1 1 1 GATA zinc finger Med3 PF11593.3 EMD61304.1 - 1 8.5 24.5 1.4 8.0 17.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ycf1 PF05758.7 EMD61304.1 - 1.3 6.6 6.2 1.3 6.6 4.3 1.2 1 0 0 1 1 1 0 Ycf1 SURF4 PF02077.10 EMD61305.1 - 3.1e-95 318.5 5.5 3.5e-95 318.3 3.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF2628 PF10947.3 EMD61305.1 - 0.18 11.5 5.6 0.49 10.2 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Peptidase_A24 PF01478.13 EMD61305.1 - 0.7 10.0 13.7 1.2 9.3 0.5 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Halogen_Hydrol PF10112.4 EMD61305.1 - 1.2 8.5 3.7 0.69 9.2 0.3 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Herpes_LMP1 PF05297.6 EMD61305.1 - 7.9 5.2 7.7 17 4.2 5.3 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) IU_nuc_hydro PF01156.14 EMD61306.1 - 4.5e-55 187.0 0.0 7.3e-53 179.8 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Zn_clus PF00172.13 EMD61307.1 - 6.7e-08 32.3 10.1 1.1e-07 31.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prp31_C PF09785.4 EMD61309.1 - 2.2e-45 154.0 2.2 2.2e-45 154.0 1.6 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EMD61309.1 - 3.4e-34 117.3 0.1 6.8e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD61309.1 - 5.8e-14 51.6 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain SGT1 PF07093.6 EMD61309.1 - 0.0044 15.4 0.6 0.0094 14.3 0.1 1.6 2 0 0 2 2 2 1 SGT1 protein HAT PF02184.11 EMD61310.1 - 3.2e-28 97.1 71.5 3.5e-14 52.2 1.7 15.0 15 1 0 15 15 15 8 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EMD61310.1 - 1.5e-19 68.6 24.8 0.024 15.2 0.2 11.5 8 3 6 14 14 12 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61310.1 - 6.8e-19 68.0 12.6 0.053 14.2 0.0 8.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61310.1 - 1.6e-14 53.9 4.4 0.0011 19.2 0.0 8.3 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61310.1 - 1.8e-09 37.0 0.6 0.43 10.9 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMD61310.1 - 1.3e-06 27.6 16.1 0.049 12.6 2.1 5.8 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61310.1 - 4.9e-05 23.1 23.6 1.7 8.6 0.0 9.3 8 2 4 12 12 12 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EMD61310.1 - 0.00031 20.4 18.8 0.038 13.7 1.3 6.5 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EMD61310.1 - 0.0056 15.6 29.5 0.0059 15.5 3.6 6.6 3 3 2 5 5 5 3 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 EMD61310.1 - 0.0076 15.9 13.2 25 4.9 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61310.1 - 0.047 13.4 5.6 9 6.3 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD61310.1 - 0.08 12.8 20.0 2.7 8.1 0.0 9.5 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD61310.1 - 1.6 9.3 22.2 42 4.8 0.1 9.1 11 0 0 11 11 10 0 Tetratricopeptide repeat adh_short PF00106.20 EMD61311.1 - 1.5e-27 96.5 0.6 2.5e-27 95.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61311.1 - 2.4e-26 93.0 0.1 2.9e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61311.1 - 1.9e-11 43.9 0.6 5e-11 42.6 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD61311.1 - 2.5e-06 27.1 0.1 3.1e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3664 PF12406.3 EMD61312.1 - 0.62 10.6 6.4 0.063 13.8 1.3 1.7 2 0 0 2 2 2 0 Surface protein BioT2 PF15368.1 EMD61313.1 - 0.017 14.8 1.5 0.023 14.4 0.1 1.7 1 1 1 2 2 2 0 Spermatogenesis family BioT2 14-3-3 PF00244.15 EMD61314.1 - 2.1e-08 33.5 0.0 6.4e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 14-3-3 protein TNFR_c6 PF00020.13 EMD61316.1 - 4.3 7.4 9.1 1.9 8.6 2.7 2.6 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region MFS_1 PF07690.11 EMD61317.1 - 7.3e-40 136.7 49.7 7.3e-40 136.7 34.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD61317.1 - 1e-09 37.5 34.5 3.3e-08 32.5 4.2 3.5 3 0 0 3 3 3 3 Sugar (and other) transporter DUF2360 PF10152.4 EMD61317.1 - 0.24 11.6 2.0 0.4 10.9 1.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SET PF00856.23 EMD61318.1 - 3.1e-09 37.3 0.0 2.1e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 SET domain RNase_H2-Ydr279 PF09468.5 EMD61319.1 - 0.037 13.2 7.5 0.046 12.9 5.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) KH_1 PF00013.24 EMD61319.1 - 0.04 13.5 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 EMD61319.1 - 0.15 11.7 0.9 0.74 9.5 0.0 2.6 4 0 0 4 4 4 0 KH domain CN_hydrolase PF00795.17 EMD61320.1 - 3.7e-37 127.4 0.0 4.6e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_int_end_N2 PF12928.2 EMD61321.1 - 5.3e-27 93.0 0.1 8.8e-27 92.3 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EMD61321.1 - 0.058 12.9 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain GCV_T PF01571.16 EMD61322.1 - 3e-64 216.2 0.0 4.1e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMD61322.1 - 1.1e-24 86.2 1.0 2e-24 85.4 0.7 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 EMD61322.1 - 0.0018 18.2 0.0 0.45 10.4 0.0 2.7 3 0 0 3 3 3 2 GTP-binding protein TrmE N-terminus V-ATPase_C PF03223.10 EMD61323.1 - 1.7e-122 408.9 0.2 1.9e-122 408.7 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C HET PF06985.6 EMD61324.1 - 1.1e-27 96.8 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 EMD61326.1 - 5.9e-16 58.1 0.0 1.4e-09 37.7 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD61326.1 - 6.7e-08 32.2 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61326.1 - 8.5e-08 31.7 0.0 0.00013 21.5 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.1 EMD61326.1 - 2.6e-07 30.6 0.0 0.021 15.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61326.1 - 7.4e-07 29.4 0.1 0.00021 21.5 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61326.1 - 3.2e-06 27.6 0.0 4.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61326.1 - 6.2e-06 25.6 0.0 0.058 13.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD61326.1 - 4.1e-05 23.1 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD61326.1 - 0.00014 21.3 0.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD61326.1 - 0.00018 21.0 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD61326.1 - 0.00033 20.7 0.0 0.00088 19.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EMD61326.1 - 0.00081 19.2 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 1 PPR repeat TPR_6 PF13174.1 EMD61326.1 - 0.0013 19.0 0.0 0.32 11.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Vps39_1 PF10366.4 EMD61326.1 - 0.0017 18.3 0.0 0.28 11.2 0.0 2.0 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_20 PF14561.1 EMD61326.1 - 0.0029 17.7 0.0 2.5 8.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61326.1 - 0.0035 17.4 0.2 2.2 8.6 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMD61326.1 - 0.0074 16.6 0.1 0.77 10.3 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EMD61326.1 - 0.04 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ATP13 PF12921.2 EMD61326.1 - 0.046 13.0 0.0 2.7 7.3 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase expression Clathrin PF00637.15 EMD61326.1 - 0.053 13.1 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS Syntaxin-18_N PF10496.4 EMD61326.1 - 0.062 13.1 0.0 12 5.7 0.0 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_9 PF13371.1 EMD61326.1 - 0.1 12.4 0.0 0.74 9.7 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat MORN_2 PF07661.8 EMD61326.1 - 0.14 12.3 0.0 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 MORN repeat variant MFS_1 PF07690.11 EMD61328.1 - 1.7e-35 122.3 36.8 1.7e-35 122.3 25.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4328 PF14219.1 EMD61328.1 - 0.02 14.2 0.7 0.02 14.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) ESSS PF10183.4 EMD61328.1 - 0.76 10.1 4.0 17 5.8 0.3 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.20 EMD61329.1 - 2e-69 233.6 0.0 3.7e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61329.1 - 5e-38 130.6 0.0 8.9e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD61329.1 - 1.2e-08 34.3 0.0 2.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD61329.1 - 0.00057 19.6 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMD61329.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Mito_carr PF00153.22 EMD61330.1 - 4.5e-71 234.6 1.3 6.8e-25 86.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EMD61330.1 - 0.061 13.3 1.2 0.17 11.8 0.0 2.5 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Dna2 PF08696.6 EMD61331.1 - 1.2e-72 243.6 0.1 2.1e-72 242.8 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.2 EMD61331.1 - 1.8e-09 37.3 0.5 5.2e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EMD61331.1 - 6.5e-08 32.6 0.1 5.4e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 DUF911 PF06023.7 EMD61331.1 - 0.0046 16.2 0.8 0.014 14.6 0.0 2.1 2 1 0 2 2 2 1 Archaeal protein of unknown function (DUF911) AAA_12 PF13087.1 EMD61332.1 - 4e-40 137.3 0.0 5.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Lectin_N PF03954.9 EMD61332.1 - 0.009 15.4 0.2 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain UvrD_C_2 PF13538.1 EMD61332.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EMD61332.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NAD_binding_8 PF13450.1 EMD61333.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD61333.1 - 3.5e-09 36.0 1.0 5.3e-09 35.4 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EMD61333.1 - 8e-07 28.4 0.0 1.3e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMD61333.1 - 1.2e-06 27.7 1.0 4.5e-06 25.7 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD61333.1 - 2.1e-06 26.4 0.5 3.2e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMD61333.1 - 2.2e-05 24.4 0.0 8.2e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD61333.1 - 2.3e-05 23.6 0.2 3.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMD61333.1 - 3.5e-05 23.0 0.5 6e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD61333.1 - 0.00022 21.5 0.1 0.00072 19.9 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD61333.1 - 0.00023 20.3 0.1 0.00048 19.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMD61333.1 - 0.00025 21.1 0.1 0.00091 19.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD61333.1 - 0.0006 18.7 0.2 0.00091 18.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMD61333.1 - 0.0017 17.3 0.1 0.0047 15.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 EMD61333.1 - 0.021 14.2 0.2 0.036 13.5 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.27 EMD61334.1 - 1.2e-07 31.3 8.1 1.4 8.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Lactonase PF10282.4 EMD61334.1 - 3.1e-05 23.2 0.1 0.2 10.7 0.0 2.8 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller Mito_carr PF00153.22 EMD61335.1 - 9.1e-50 166.3 5.9 3.2e-18 65.2 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 EMD61335.1 - 0.2 11.7 0.8 0.53 10.4 0.1 2.0 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF3337 PF11816.3 EMD61336.1 - 1.7e-86 290.6 0.0 9e-83 278.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EMD61336.1 - 1.6e-30 103.8 13.5 1.2e-08 34.5 0.0 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 EMD61336.1 - 4.4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD61336.1 - 0.00042 20.4 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD61336.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD61336.1 - 0.00093 19.0 0.0 0.018 14.8 0.0 2.9 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EMD61337.1 - 1.4e-43 149.0 49.2 1.7e-43 148.7 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD61337.1 - 3.7e-26 91.5 38.9 5.1e-26 91.0 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease YrhK PF14145.1 EMD61338.1 - 0.011 15.4 3.6 0.013 15.1 0.4 2.5 2 0 0 2 2 2 0 YrhK-like protein Cu-oxidase_3 PF07732.10 EMD61339.1 - 2.6e-42 143.2 12.8 2.8e-41 139.9 1.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD61339.1 - 6.9e-40 135.7 14.7 1.6e-37 128.1 2.0 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EMD61339.1 - 1.8e-34 118.9 0.6 4e-34 117.8 0.4 1.6 1 0 0 1 1 1 1 Multicopper oxidase DUF1687 PF07955.6 EMD61339.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Ribonuc_P_40 PF08584.6 EMD61342.1 - 1.5e-78 263.6 0.0 2.2e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit SIR2 PF02146.12 EMD61344.1 - 3.2e-55 186.5 0.0 5.3e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EMD61344.1 - 0.0082 15.9 0.2 2.6 7.7 0.1 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.8 EMD61344.1 - 0.038 13.5 0.1 0.097 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF592) Pectate_lyase PF03211.8 EMD61346.1 - 6e-65 218.6 5.0 7.8e-65 218.2 3.5 1.0 1 0 0 1 1 1 1 Pectate lyase ABC2_membrane PF01061.19 EMD61347.1 - 4.6e-80 267.7 57.8 2.5e-43 147.7 12.0 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EMD61347.1 - 1.7e-34 119.0 0.0 1.1e-16 61.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EMD61347.1 - 4.5e-34 116.2 0.9 2.7e-30 104.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMD61347.1 - 2e-17 63.0 0.0 4.9e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EMD61347.1 - 6.2e-07 28.7 48.4 6.7e-06 25.3 12.1 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EMD61347.1 - 6.1e-06 25.7 0.1 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD61347.1 - 1e-05 24.7 0.0 0.0006 19.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD61347.1 - 1.9e-05 24.6 0.8 0.0067 16.4 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EMD61347.1 - 4.4e-05 23.3 0.0 0.02 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD61347.1 - 0.00015 22.0 0.0 0.073 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EMD61347.1 - 0.00015 21.2 0.4 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD61347.1 - 0.00024 20.5 0.5 0.03 13.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EMD61347.1 - 0.0004 20.3 0.3 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMD61347.1 - 0.00064 20.5 0.3 0.3 11.9 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.1 EMD61347.1 - 0.0034 17.0 0.2 2.5 7.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 EMD61347.1 - 0.0075 15.5 0.0 1.3 8.1 0.0 3.5 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EMD61347.1 - 0.01 15.5 0.7 3.5 7.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EMD61347.1 - 0.013 15.4 0.0 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EMD61347.1 - 0.017 15.2 0.3 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMD61347.1 - 0.022 14.9 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMD61347.1 - 0.21 12.0 0.0 37 4.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EMD61347.1 - 0.26 10.7 1.3 5.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Zn_clus PF00172.13 EMD61348.1 - 4.4e-08 32.8 11.4 1.2e-07 31.5 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD61348.1 - 0.049 12.4 0.1 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ctr PF04145.10 EMD61349.1 - 0.011 15.8 0.1 0.028 14.4 0.1 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DUF4083 PF13314.1 EMD61349.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3638 PF12340.3 EMD61351.1 - 4e-89 297.5 0.7 8.5e-89 296.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EMD61351.1 - 3.2e-17 61.3 0.9 7.5e-17 60.1 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) rve_2 PF13333.1 EMD61351.1 - 0.043 13.8 0.7 17 5.5 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain WH2 PF02205.15 EMD61352.1 - 8.4e-11 41.1 0.4 2.3e-10 39.7 0.3 1.8 1 0 0 1 1 1 1 WH2 motif YlqD PF11068.3 EMD61354.1 - 0.0033 17.4 1.0 0.0042 17.1 0.7 1.1 1 0 0 1 1 1 1 YlqD protein tRNA_synt_2f PF02092.12 EMD61354.1 - 0.013 14.0 0.1 0.015 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit Thioesterase PF00975.15 EMD61354.1 - 0.059 13.5 0.2 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF4446 PF14584.1 EMD61354.1 - 0.13 12.1 1.0 0.18 11.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FlbT PF07378.6 EMD61354.1 - 0.16 11.8 0.6 0.21 11.4 0.4 1.1 1 0 0 1 1 1 0 Flagellar protein FlbT Glyco_hydro_62 PF03664.8 EMD61355.1 - 1.6e-153 509.5 13.0 1.8e-153 509.3 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Haem_oxygenas_2 PF14518.1 EMD61356.1 - 2.9e-13 49.8 0.1 8.6e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF3050 PF11251.3 EMD61356.1 - 0.012 14.8 0.1 0.4 9.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3050) Methyltransf_26 PF13659.1 EMD61357.1 - 2.1e-13 50.3 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD61357.1 - 4.6e-13 48.8 0.0 7.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMD61357.1 - 2.4e-12 46.7 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61357.1 - 2.7e-08 34.3 0.0 5.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMD61357.1 - 1.4e-06 27.9 0.0 3.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EMD61357.1 - 3.6e-06 27.2 0.0 7.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD61357.1 - 6.6e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EMD61357.1 - 8.9e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.11 EMD61357.1 - 9.7e-05 21.5 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_4 PF02390.12 EMD61357.1 - 0.0013 17.8 0.0 0.0049 15.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EMD61357.1 - 0.0017 17.5 0.0 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EMD61357.1 - 0.0048 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61357.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EMD61357.1 - 0.021 14.2 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.11 EMD61357.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.13 EMD61357.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Phosphoesterase PF04185.9 EMD61358.1 - 1.1e-37 130.1 1.5 3.2e-37 128.6 1.0 1.6 1 1 1 2 2 2 1 Phosphoesterase family Sulfatase PF00884.18 EMD61358.1 - 0.0023 17.1 0.1 0.0048 16.1 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Cu-oxidase_3 PF07732.10 EMD61359.1 - 1.9e-45 153.3 0.9 1.9e-45 153.3 0.6 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD61359.1 - 7.6e-39 132.3 6.9 7.3e-33 112.9 0.2 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EMD61359.1 - 3.4e-32 111.5 0.0 2.8e-31 108.5 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Methyltransf_31 PF13847.1 EMD61361.1 - 0.00053 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61361.1 - 0.00072 20.1 0.0 0.0056 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD61361.1 - 0.001 18.2 0.0 0.0073 15.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMD61361.1 - 0.0013 19.2 0.0 0.0026 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD61361.1 - 0.0066 16.9 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMD61361.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD61361.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GST_N_3 PF13417.1 EMD61362.1 - 5.3e-07 29.7 0.2 1.5e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD61362.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD61362.1 - 0.00022 21.1 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD61362.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD61362.1 - 0.052 14.0 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3680 PF12441.3 EMD61362.1 - 0.15 11.9 1.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) Rad60-SLD PF11976.3 EMD61364.1 - 0.005 16.5 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMD61364.1 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family IFT57 PF10498.4 EMD61364.1 - 0.13 10.9 1.3 0.19 10.4 0.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Duffy_binding PF05424.6 EMD61364.1 - 0.16 11.7 0.4 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Duffy binding domain PH_6 PF15406.1 EMD61365.1 - 2e-32 111.5 2.0 2e-32 111.5 1.4 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain ATP_bind_3 PF01171.15 EMD61367.1 - 9.6e-44 149.0 0.0 1.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EMD61367.1 - 8e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Cpn10 PF00166.16 EMD61368.1 - 9e-26 89.6 0.0 1e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Het-C PF07217.6 EMD61369.1 - 6e-278 923.0 0.0 7.4e-278 922.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Ank_2 PF12796.2 EMD61370.1 - 3.9e-24 84.8 0.2 4.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD61370.1 - 1.3e-23 81.4 0.6 3.2e-09 36.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD61370.1 - 4e-21 72.9 0.2 9.9e-08 31.5 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMD61370.1 - 6.9e-19 67.4 0.9 9.5e-09 35.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD61370.1 - 9.4e-18 64.2 0.4 4.9e-12 46.0 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Strabismus PF06638.6 EMD61370.1 - 0.15 10.3 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 Strabismus protein Eno-Rase_FAD_bd PF07055.7 EMD61371.1 - 0.063 13.2 0.3 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Pilt PF15453.1 EMD61371.1 - 0.38 10.4 6.8 0.4 10.3 4.7 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Hom_end_hint PF05203.11 EMD61371.1 - 0.83 9.3 5.9 0.95 9.1 4.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint V_ATPase_I PF01496.14 EMD61371.1 - 1 7.1 4.5 1.1 6.9 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 EMD61371.1 - 1.9 6.6 11.6 1.9 6.6 8.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.5 EMD61371.1 - 4.1 7.3 12.8 5.1 7.0 8.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 EMD61371.1 - 4.3 4.9 7.5 4.8 4.7 5.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4452 PF14618.1 EMD61373.1 - 3.8e-66 221.9 12.9 5.2e-66 221.5 9.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.18 EMD61374.1 - 9.5e-16 57.5 1.5 6.6e-12 45.1 0.1 2.6 2 1 0 3 3 3 2 Cyclin, N-terminal domain TFIIB PF00382.14 EMD61374.1 - 0.033 14.0 0.4 0.07 12.9 0.3 1.7 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Mito_carr PF00153.22 EMD61375.1 - 2.8e-63 209.6 7.5 1.4e-21 75.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMD61375.1 - 4.3e-26 90.8 2.8 3.2e-14 52.8 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMD61375.1 - 5.2e-25 84.7 1.0 1.9e-06 26.7 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 EMD61375.1 - 1.2e-21 74.9 3.0 3.4e-06 26.1 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMD61375.1 - 2.9e-21 74.8 0.7 1.6e-10 40.4 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EMD61375.1 - 2.2e-18 64.4 4.0 2.8e-06 26.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.4 EMD61375.1 - 3.6e-11 43.0 0.0 1.5e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMD61375.1 - 0.029 14.1 1.0 2.8 7.7 0.0 2.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMD61375.1 - 0.23 11.1 0.4 6.2 6.5 0.1 2.8 1 1 2 3 3 3 0 EF hand SNARE PF05739.14 EMD61376.1 - 4.7e-11 42.2 3.1 4.7e-11 42.2 2.1 2.2 2 0 0 2 2 2 1 SNARE domain Phage_GP20 PF06810.6 EMD61376.1 - 0.0042 16.5 1.3 0.74 9.2 0.1 2.3 2 0 0 2 2 2 2 Phage minor structural protein GP20 Use1 PF09753.4 EMD61376.1 - 0.013 14.9 0.6 0.02 14.3 0.4 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.16 EMD61376.1 - 0.054 13.0 0.4 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Synaptobrevin ALIX_LYPXL_bnd PF13949.1 EMD61376.1 - 0.064 12.2 8.5 0.88 8.4 0.9 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Allexi_40kDa PF05549.6 EMD61376.1 - 0.091 12.0 1.5 0.16 11.2 1.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein CorA PF01544.13 EMD61376.1 - 0.096 11.7 0.0 0.096 11.7 0.0 2.9 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF2077 PF09850.4 EMD61376.1 - 0.14 11.5 1.1 2.1 7.6 0.0 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) WXG100 PF06013.7 EMD61376.1 - 0.15 12.1 2.3 0.83 9.7 0.3 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Laminin_II PF06009.7 EMD61376.1 - 0.67 9.7 4.0 1.9 8.2 0.8 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF883 PF05957.8 EMD61376.1 - 1.4 9.4 3.9 6.6 7.2 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Mito_carr PF00153.22 EMD61377.1 - 7.4e-44 147.3 3.4 1.7e-17 62.9 0.1 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein RIC1 PF07064.8 EMD61378.1 - 1.2e-92 309.9 0.1 1.7e-92 309.4 0.1 1.2 1 0 0 1 1 1 1 RIC1 Inhibitor_I78 PF11720.3 EMD61380.1 - 1.6e-11 43.7 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EMD61380.1 - 0.00074 19.6 0.0 0.00087 19.3 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family CBFD_NFYB_HMF PF00808.18 EMD61381.1 - 2.6e-10 40.1 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD61381.1 - 5.6e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Daxx PF03344.10 EMD61381.1 - 0.26 9.7 24.2 0.34 9.3 16.8 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EMD61381.1 - 1.3 7.9 17.5 1.5 7.7 12.1 1.1 1 0 0 1 1 1 0 BUD22 B3_4 PF03483.12 EMD61382.1 - 0.099 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 B3/4 domain Herpes_LMP1 PF05297.6 EMD61382.1 - 5.1 5.9 5.2 6.6 5.5 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SUZ PF12752.2 EMD61383.1 - 0.00021 21.7 13.3 0.00021 21.7 9.2 3.4 4 1 0 4 4 4 1 SUZ domain Ycf1 PF05758.7 EMD61383.1 - 0.05 11.3 0.6 0.068 10.8 0.4 1.2 1 0 0 1 1 1 0 Ycf1 TFIIA PF03153.8 EMD61383.1 - 3.1 7.6 12.9 3.8 7.3 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 EMD61383.1 - 5.9 5.7 6.3 0.81 8.5 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HATPase_c_2 PF13581.1 EMD61384.1 - 0.085 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain bZIP_1 PF00170.16 EMD61385.1 - 1.4e-08 34.5 1.8 1.4e-08 34.5 1.2 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMD61385.1 - 7.3e-05 22.5 4.0 0.00016 21.4 2.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD61385.1 - 0.0049 17.1 1.3 0.0084 16.3 0.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 EMD61385.1 - 0.061 12.8 0.4 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Rbsn PF11464.3 EMD61385.1 - 0.091 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Zn_clus PF00172.13 EMD61386.1 - 9e-10 38.3 7.7 2.4e-09 36.9 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK_II_beta PF01214.13 EMD61387.1 - 1e-71 240.2 0.2 1.4e-71 239.7 0.2 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Kri1 PF05178.7 EMD61387.1 - 0.74 10.1 9.6 0.11 12.7 3.9 1.6 2 0 0 2 2 2 0 KRI1-like family SLD3 PF08639.5 EMD61391.1 - 9.8e-106 354.3 5.8 1.3e-105 353.9 4.0 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 MRJP PF03022.11 EMD61391.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein 2-oxoacid_dh PF00198.18 EMD61392.1 - 3.2e-72 242.5 0.0 5.5e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMD61392.1 - 2.4e-19 68.7 0.1 6.1e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EMD61392.1 - 3.6e-12 45.7 0.2 1.2e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMD61392.1 - 0.00039 20.0 0.0 0.22 11.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Prefoldin_2 PF01920.15 EMD61393.1 - 1.1e-16 60.4 5.9 1.2e-16 60.3 3.5 1.5 1 1 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.10 EMD61393.1 - 0.0026 17.4 7.5 0.075 12.7 0.6 2.4 2 1 1 3 3 3 2 RasGAP C-terminus Vac_Fusion PF02346.11 EMD61393.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF3552 PF12072.3 EMD61393.1 - 0.018 14.2 0.4 0.018 14.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4200 PF13863.1 EMD61393.1 - 0.85 9.5 7.8 2.7 7.9 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YlqD PF11068.3 EMD61393.1 - 3.2 7.8 9.3 0.66 10.0 1.7 2.0 1 1 1 2 2 2 0 YlqD protein DivIC PF04977.10 EMD61393.1 - 7.3 6.1 11.5 1.3 8.5 1.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Ceramidase PF05875.7 EMD61394.1 - 5.9e-106 353.4 10.4 7.1e-106 353.1 7.2 1.1 1 0 0 1 1 1 1 Ceramidase DUF788 PF05620.6 EMD61394.1 - 0.34 10.7 4.8 0.59 9.9 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Tubulin PF00091.20 EMD61395.1 - 6.9e-70 235.2 0.0 1.2e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD61395.1 - 6.3e-49 165.2 0.1 1.1e-48 164.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMD61395.1 - 2.1e-05 24.5 0.2 5.1e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMD61395.1 - 0.0042 16.5 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HMG_box_2 PF09011.5 EMD61396.1 - 2.6e-07 30.8 11.7 9.3e-06 25.9 0.1 3.6 2 1 2 4 4 4 2 HMG-box domain HMG_box PF00505.14 EMD61396.1 - 2.3e-05 24.5 0.3 2.3e-05 24.5 0.2 4.0 4 2 1 5 5 5 2 HMG (high mobility group) box SOBP PF15279.1 EMD61396.1 - 2.3 8.4 13.1 3.4 7.9 9.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein YABBY PF04690.8 EMD61396.1 - 2.8 8.1 10.5 1.9 8.7 5.6 1.9 1 1 1 2 2 2 0 YABBY protein Med3 PF11593.3 EMD61396.1 - 7.3 5.7 15.5 10 5.2 10.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aminotran_4 PF01063.14 EMD61397.1 - 7.1e-29 100.9 0.0 9.3e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EMD61398.1 - 1.2e-17 63.9 0.0 3.2e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61398.1 - 3e-09 36.3 0.0 1.4e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.4 EMD61398.1 - 0.21 11.4 0.3 0.88 9.4 0.0 2.0 2 0 0 2 2 2 0 Parkin co-regulated protein Aa_trans PF01490.13 EMD61399.1 - 7.8e-27 93.7 34.4 9.5e-27 93.4 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NACHT PF05729.7 EMD61400.1 - 2e-06 27.5 0.0 4.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMD61400.1 - 2.9e-05 24.2 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD61400.1 - 0.00014 21.9 0.0 0.00086 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EMD61400.1 - 0.0052 15.7 0.0 0.012 14.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EMD61400.1 - 0.0099 16.0 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMD61400.1 - 0.011 15.8 0.0 0.04 14.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMD61400.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD61400.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain GntP_permease PF02447.11 EMD61400.1 - 0.57 8.6 0.0 0.91 7.9 0.0 1.2 1 0 0 1 1 1 0 GntP family permease PEMT PF04191.8 EMD61401.1 - 1.9e-31 108.3 1.2 4.4e-31 107.1 0.8 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF2374 PF09574.5 EMD61401.1 - 0.98 9.0 5.8 10 5.8 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (Duf2374) DUF1282 PF06930.7 EMD61401.1 - 2.3 7.8 8.3 20 4.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) PAP2 PF01569.16 EMD61402.1 - 1.5e-22 79.6 1.5 1.5e-22 79.6 1.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily Ank_5 PF13857.1 EMD61403.1 - 2.1e-11 43.6 0.2 6.6e-08 32.5 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD61403.1 - 1.2e-07 32.0 0.0 4e-06 27.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EMD61403.1 - 1.3e-07 31.0 0.5 0.00018 21.1 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMD61403.1 - 1.2e-05 25.6 0.1 2.4e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD61403.1 - 5.1e-05 23.1 0.1 0.0081 16.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF3808 PF10300.4 EMD61404.1 - 3.2e-133 444.7 0.2 3.9e-133 444.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EMD61404.1 - 0.00027 20.5 8.6 0.013 15.1 1.4 4.0 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 EMD61404.1 - 0.004 16.9 11.6 0.33 10.9 0.2 5.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_5 PF12688.2 EMD61404.1 - 0.0082 16.1 0.0 0.11 12.5 0.0 2.7 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_1 PF00515.23 EMD61404.1 - 0.069 12.7 1.5 26 4.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61404.1 - 0.081 12.7 7.4 3.8 7.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61404.1 - 0.11 12.4 8.9 6.5 6.7 0.3 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61404.1 - 0.18 12.5 0.9 2.1 9.2 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.8 EMD61405.1 - 1.2e-22 79.4 12.0 1.6e-22 79.0 8.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Prothymosin PF03247.9 EMD61405.1 - 1.9 8.7 8.7 2.7 8.2 6.0 1.3 1 1 0 1 1 1 0 Prothymosin/parathymosin family PGK PF00162.14 EMD61406.1 - 2.6e-152 506.8 1.3 2.9e-152 506.6 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 EMD61406.1 - 0.065 13.4 0.7 2.1 8.6 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain Mpv17_PMP22 PF04117.7 EMD61407.1 - 8.2e-24 83.0 0.2 3e-23 81.2 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Trs65 PF12735.2 EMD61408.1 - 5.6e-71 239.3 0.3 7.2e-71 239.0 0.2 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 EMD61409.1 - 1.3e-42 143.5 14.2 1.1e-11 44.4 1.2 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.21 EMD61409.1 - 3e-14 52.5 16.7 3.2e-07 30.0 6.1 2.8 2 0 0 2 2 2 2 WW domain Acyl-CoA_dh_1 PF00441.19 EMD61410.1 - 2.8e-30 105.4 1.3 4e-30 104.9 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD61410.1 - 3.1e-20 71.4 1.4 5.2e-20 70.7 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD61410.1 - 1.6e-13 51.1 1.3 8.8e-13 48.8 0.2 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD61410.1 - 8.4e-06 26.0 0.3 1.7e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1447 PF07288.6 EMD61411.1 - 0.075 12.8 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Fungal_trans PF04082.13 EMD61412.1 - 3.3e-39 134.3 0.2 9.4e-39 132.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61412.1 - 0.00021 21.1 15.5 0.00035 20.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.15 EMD61413.1 - 4e-52 176.8 0.0 1.2e-49 168.7 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 EMD61413.1 - 4.2e-10 39.7 0.1 3.2e-09 36.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Sterol-sensing PF12349.3 EMD61414.1 - 5.9e-31 106.9 4.7 1.4e-30 105.8 3.2 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMD61414.1 - 1.4e-10 39.7 2.6 2.2e-10 39.1 1.8 1.2 1 0 0 1 1 1 1 Patched family TPR_12 PF13424.1 EMD61414.1 - 8.8e-09 35.1 0.9 0.0023 17.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61414.1 - 1.9e-08 33.7 4.6 6.6e-05 22.4 0.0 4.0 3 1 2 5 5 4 3 TPR repeat TPR_2 PF07719.12 EMD61414.1 - 1e-07 31.2 0.0 0.0035 17.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61414.1 - 4.1e-06 27.3 10.4 0.011 16.4 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61414.1 - 5.6e-05 23.4 5.2 1.3 9.8 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD61414.1 - 0.00023 20.6 0.8 0.021 14.3 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61414.1 - 0.00082 18.9 0.0 0.047 13.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD61414.1 - 0.0082 16.5 0.8 20 5.9 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMD61414.1 - 0.013 15.3 6.4 3.2 7.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61414.1 - 0.018 15.3 6.9 1.3 9.3 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD61414.1 - 0.045 13.5 0.0 6.9 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61414.1 - 0.082 13.1 0.1 15 6.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Complex1_LYR PF05347.10 EMD61415.1 - 1.1e-11 44.3 1.7 1.5e-11 43.9 0.3 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD61415.1 - 1.7e-09 37.7 1.8 4.5e-09 36.3 0.2 2.2 2 0 0 2 2 2 1 Complex1_LYR-like gpW PF02831.10 EMD61415.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 gpW UQ_con PF00179.21 EMD61416.1 - 1.1e-17 63.7 0.0 1.2e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMD61416.1 - 0.0099 15.7 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 EMD61417.1 - 4.5e-40 136.8 6.6 3.1e-39 134.1 0.6 4.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMD61417.1 - 6.9e-06 25.5 3.6 0.096 12.2 0.0 6.1 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) HEAT PF02985.17 EMD61417.1 - 0.043 13.9 4.8 0.79 9.9 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Fungal_trans PF04082.13 EMD61418.1 - 7.5e-15 54.5 0.7 2e-14 53.0 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61418.1 - 2.7e-08 33.5 14.0 4.7e-08 32.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aft1_HRR PF11787.3 EMD61418.1 - 5.2 8.1 7.6 0.35 11.9 0.3 2.4 2 0 0 2 2 2 0 Aft1 HRR domain CK_II_beta PF01214.13 EMD61419.1 - 1.9e-76 255.6 0.0 4.6e-76 254.4 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EMD61419.1 - 0.0013 19.3 6.9 0.0013 19.3 4.8 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 EMD61419.1 - 0.41 9.7 6.8 2.7 7.0 3.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Ammonium_transp PF00909.16 EMD61420.1 - 1.1e-114 383.0 25.4 1.3e-114 382.8 17.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tfb4 PF03850.9 EMD61421.1 - 5.2e-105 350.6 0.0 6.2e-105 350.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EMD61421.1 - 0.0086 16.1 0.1 0.02 15.0 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-C2HC5 PF06221.8 EMD61421.1 - 0.17 11.6 3.4 0.27 11.0 2.4 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Pyr_redox_3 PF13738.1 EMD61422.1 - 3.5e-23 82.7 0.0 1.2e-22 80.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD61422.1 - 6.2e-11 41.1 0.4 1.8e-10 39.6 0.3 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD61422.1 - 3.1e-09 36.7 1.7 4.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMD61422.1 - 3.6e-07 29.4 0.0 2.9e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD61422.1 - 0.00085 19.2 0.0 0.0035 17.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD61422.1 - 0.001 18.2 0.4 0.0089 15.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EMD61422.1 - 0.011 15.4 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EMD61422.1 - 0.036 12.9 2.7 0.61 8.9 1.7 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD61422.1 - 0.054 11.9 0.2 0.1 11.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EMD61422.1 - 0.15 10.9 0.1 0.31 9.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Skp1_POZ PF03931.10 EMD61423.1 - 2.5e-11 43.4 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short PF00106.20 EMD61424.1 - 5.2e-23 81.7 0.2 1.7e-14 54.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61424.1 - 8.5e-14 51.8 0.0 1.7e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61424.1 - 9.2e-07 28.6 0.2 1.8e-05 24.5 0.1 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD61424.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMD61424.1 - 0.016 14.6 0.4 0.079 12.3 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMD61424.1 - 0.023 14.4 0.4 0.067 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Med12-LCEWAV PF12145.3 EMD61424.1 - 0.071 11.5 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain 3HCDH_N PF02737.13 EMD61424.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EMD61425.1 - 1.9e-41 141.0 0.1 4.5e-41 139.8 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EMD61425.1 - 9.7e-28 95.5 0.1 7e-27 92.8 0.2 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMD61425.1 - 1.8e-21 75.2 2.0 3.3e-21 74.3 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EMD61425.1 - 2e-16 59.8 3.7 4.2e-16 58.8 2.6 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EMD61425.1 - 2e-05 24.7 0.1 0.00041 20.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EMD61425.1 - 0.00055 20.1 0.9 0.0047 17.1 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding DUF2419 PF10343.4 EMD61426.1 - 3.6e-134 446.5 0.3 4.4e-134 446.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) FAD_binding_4 PF01565.18 EMD61427.1 - 2.1e-31 108.2 2.3 3.7e-31 107.4 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD61427.1 - 2.2e-12 46.6 0.1 6.1e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Ribonucleas_3_3 PF14622.1 EMD61429.1 - 2.5e-06 27.4 0.0 6.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD61429.1 - 2.1e-05 24.9 1.5 0.00029 21.2 0.0 3.0 2 1 0 2 2 2 1 Ribonuclease III domain tRNA-synt_2b PF00587.20 EMD61430.1 - 3.1e-33 114.7 0.0 4.6e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD61430.1 - 5.9e-10 38.9 0.1 1.7e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMD61430.1 - 0.031 13.0 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Rubredoxin PF00301.15 EMD61430.1 - 0.3 11.0 2.5 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin Ribosomal_L10 PF00466.15 EMD61431.1 - 7e-05 22.6 0.5 0.0074 16.2 0.3 2.8 1 1 0 1 1 1 1 Ribosomal protein L10 DUF3436 PF11918.3 EMD61431.1 - 0.089 13.0 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) Rox3 PF08633.5 EMD61432.1 - 5.4e-29 101.8 0.7 1.5e-28 100.4 0.0 2.0 2 1 0 2 2 2 1 Rox3 mediator complex subunit Rad10 PF03834.9 EMD61433.1 - 3.5e-32 109.9 0.0 5.1e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EMD61433.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sugar_tr PF00083.19 EMD61434.1 - 2e-92 310.1 27.6 2.3e-92 309.9 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61434.1 - 2.4e-31 108.7 28.6 3e-24 85.3 3.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD61434.1 - 2.3e-08 32.8 28.4 6.2e-05 21.5 5.0 3.1 2 1 0 3 3 3 2 MFS/sugar transport protein TMA7 PF09072.5 EMD61435.1 - 4e-14 52.8 10.2 4.2e-14 52.7 7.1 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 DBR1 PF05011.8 EMD61437.1 - 5.8e-52 175.4 1.9 7.4e-52 175.1 0.4 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EMD61437.1 - 1.3e-06 27.9 0.2 3.3e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.11 EMD61438.1 - 7.4e-12 44.9 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 EMD61438.1 - 0.0017 17.9 0.3 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Nudix N-terminal Cytochrome_C554 PF13435.1 EMD61438.1 - 0.37 10.8 3.4 0.77 9.8 2.4 1.8 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zf-ZPR1 PF03367.8 EMD61439.1 - 5.8e-109 360.4 1.1 1e-54 184.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EMD61439.1 - 0.033 13.8 2.8 3.3 7.4 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family IL34 PF15036.1 EMD61439.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 Baculo_PEP_C PF04513.7 EMD61439.1 - 0.1 12.3 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSBA PF01323.15 EMD61439.1 - 0.19 11.2 0.8 5.2 6.5 0.1 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Ribosomal_L32p PF01783.18 EMD61439.1 - 4.2 7.6 6.1 0.92 9.7 0.6 2.5 3 0 0 3 3 3 0 Ribosomal L32p protein family Arrestin_C PF02752.17 EMD61440.1 - 4e-15 56.1 0.0 1.7e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Fe_hyd_lg_C PF02906.9 EMD61441.1 - 6.6e-62 209.3 0.0 1.2e-61 208.4 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.20 EMD61442.1 - 5.5e-59 199.4 0.0 8.2e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61442.1 - 4.3e-30 104.6 0.0 2.2e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMD61442.1 - 0.034 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EMD61442.1 - 0.79 9.2 0.0 0.79 9.2 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1387) Kinesin PF00225.18 EMD61446.1 - 1.7e-90 303.1 1.2 4.3e-90 301.8 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain DUF904 PF06005.7 EMD61446.1 - 0.88 9.9 0.0 0.88 9.9 0.0 13.8 6 2 4 11 11 11 0 Protein of unknown function (DUF904) TPR_10 PF13374.1 EMD61447.1 - 2.6e-49 163.8 2.2 4.4e-13 48.6 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61447.1 - 2.1e-48 162.1 8.3 6.8e-16 57.9 0.0 4.3 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD61447.1 - 9.3e-13 46.9 3.6 0.0084 15.8 0.1 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EMD61447.1 - 1.8e-12 46.7 0.3 8e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_11 PF13414.1 EMD61447.1 - 4.4e-11 42.2 0.4 8.6e-05 22.1 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMD61447.1 - 4.4e-09 35.5 0.6 0.28 10.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 EMD61447.1 - 4.4e-09 36.5 0.2 2.4e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 EMD61447.1 - 1e-08 35.6 2.9 0.0022 18.6 0.0 5.1 3 1 3 6 6 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 EMD61447.1 - 1.5e-07 31.5 0.5 1.5e-07 31.5 0.3 2.7 3 1 0 3 3 2 1 AAA ATPase domain TPR_2 PF07719.12 EMD61447.1 - 2.1e-07 30.3 6.9 1 9.4 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD61447.1 - 6.9e-06 26.1 1.9 0.0084 16.2 0.1 3.7 2 1 2 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 EMD61447.1 - 1.1e-05 25.1 0.1 3.4e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 NACHT domain TPR_4 PF07721.9 EMD61447.1 - 1.6e-05 24.8 2.2 0.14 12.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61447.1 - 3.3e-05 24.1 6.5 0.11 12.9 0.0 5.2 2 1 2 5 5 5 1 Tetratricopeptide repeat AAA PF00004.24 EMD61447.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_3 PF07720.7 EMD61447.1 - 0.00057 19.6 0.0 0.011 15.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat IstB_IS21 PF01695.12 EMD61447.1 - 0.00077 18.9 0.0 0.0023 17.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EMD61447.1 - 0.00083 18.8 0.0 0.0026 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD61447.1 - 0.0015 19.3 0.1 0.0069 17.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain TPR_6 PF13174.1 EMD61447.1 - 0.0045 17.3 5.9 2.2 8.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61447.1 - 0.0056 16.7 1.6 11 6.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_18 PF13238.1 EMD61447.1 - 0.009 16.3 0.1 0.037 14.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMD61447.1 - 0.01 15.5 0.0 0.037 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EMD61447.1 - 0.011 16.0 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter CaATP_NAI PF12515.3 EMD61447.1 - 0.016 14.7 0.5 0.5 9.9 0.0 3.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain TPR_8 PF13181.1 EMD61447.1 - 0.02 14.6 0.0 51 3.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61447.1 - 0.046 14.3 10.6 19 6.2 0.0 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EMD61447.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EMD61447.1 - 0.05 13.4 0.7 0.49 10.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain RTC_insert PF05189.8 EMD61447.1 - 0.13 12.2 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain AAA_10 PF12846.2 EMD61447.1 - 0.16 11.3 1.1 1.1 8.5 0.1 2.6 1 1 1 2 2 2 0 AAA-like domain CSTF2_hinge PF14327.1 EMD61447.1 - 0.19 11.8 2.9 0.19 11.8 0.4 2.2 2 0 0 2 2 1 0 Hinge domain of cleavage stimulation factor subunit 2 DENN PF02141.16 EMD61448.1 - 1e-41 142.7 0.1 1.8e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EMD61448.1 - 0.00017 21.4 0.0 0.00047 20.0 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EMD61448.1 - 0.0026 18.1 6.9 0.0026 18.1 4.8 2.4 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A LPP PF04728.8 EMD61448.1 - 0.36 10.6 3.4 0.38 10.5 0.7 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF2570 PF10828.3 EMD61448.1 - 2.6 7.6 10.5 2.5 7.7 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) zf-HIT PF04438.11 EMD61449.1 - 6.4e-10 38.4 11.2 1e-09 37.8 7.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Sdh5 PF03937.11 EMD61449.1 - 0.033 13.8 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase APS_kinase PF01583.15 EMD61450.1 - 1.5e-71 239.1 0.0 1.8e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EMD61450.1 - 2.7e-08 34.6 0.0 3.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD61450.1 - 3.1e-07 30.3 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD61450.1 - 1.6e-05 25.1 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMD61450.1 - 0.00071 18.8 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EMD61450.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 EMD61450.1 - 0.067 12.2 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_23 PF13476.1 EMD61450.1 - 0.14 12.4 0.2 0.32 11.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF3336 PF11815.3 EMD61451.1 - 1.2e-34 118.9 4.2 1.9e-34 118.2 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMD61451.1 - 4.5e-21 75.7 0.5 9.9e-21 74.5 0.2 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase CPDase PF07823.6 EMD61452.1 - 5.3e-34 117.4 0.0 6e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EMD61452.1 - 8.1e-05 22.3 0.0 0.019 14.7 0.0 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF2738 PF10927.3 EMD61452.1 - 0.035 13.1 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) EF-hand_1 PF00036.27 EMD61453.1 - 4.9e-05 22.3 4.2 0.96 8.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMD61453.1 - 5.2e-05 23.3 5.1 0.19 11.8 1.5 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMD61453.1 - 5.7e-05 22.2 6.0 0.43 10.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMD61453.1 - 0.00011 21.8 4.7 2 8.5 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EMD61453.1 - 3.3 7.3 4.4 96 2.7 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair Dockerin_1 PF00404.13 EMD61453.1 - 6.3 6.6 14.7 2.4 8.0 0.4 3.3 3 0 0 3 3 3 0 Dockerin type I repeat AA_permease PF00324.16 EMD61455.1 - 4.6e-113 378.1 33.8 5.5e-113 377.8 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD61455.1 - 4.2e-20 71.6 37.1 5.7e-20 71.2 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EMD61457.1 - 1e-33 116.5 0.0 1.2e-21 77.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61457.1 - 6.3e-17 61.5 0.0 2.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EMD61457.1 - 0.054 12.5 0.0 0.16 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD61457.1 - 0.057 12.3 0.0 2.9 6.7 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Sigma70_r4_2 PF08281.7 EMD61457.1 - 0.088 12.2 0.0 10 5.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EMD61457.1 - 0.095 11.8 0.0 0.77 8.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 F-box PF00646.28 EMD61458.1 - 1.7e-11 43.4 0.0 5.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD61458.1 - 1e-10 41.1 0.3 1.8e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EMD61458.1 - 0.023 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain RNase_PH PF01138.16 EMD61459.1 - 2.7e-20 73.0 0.0 4.6e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MFS_1 PF07690.11 EMD61460.1 - 4e-12 45.5 26.6 4e-12 45.5 18.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EMD61460.1 - 1.8e-08 33.9 2.7 1.8e-08 33.9 1.9 2.3 2 0 0 2 2 2 1 Nodulin-like 7tm_7 PF08395.7 EMD61460.1 - 0.0042 16.1 2.7 0.37 9.7 0.2 2.8 3 0 0 3 3 3 2 7tm Chemosensory receptor ATP-grasp_2 PF08442.5 EMD61461.1 - 3.1e-08 33.2 0.0 4.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EMD61462.1 - 4.5e-18 65.0 0.0 4.4e-15 55.2 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EMD61462.1 - 6.7e-17 61.7 0.0 1.7e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EMD61462.1 - 2.1e-14 53.3 0.3 3.8e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMD61462.1 - 3.6e-06 26.6 0.0 5.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EMD61462.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain His_Phos_2 PF00328.17 EMD61463.1 - 1.9e-16 60.3 0.1 4.6e-16 59.0 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1628 PF07790.6 EMD61463.1 - 0.00023 21.8 0.2 0.00098 19.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1628) Granulin PF00396.13 EMD61464.1 - 1.5 8.9 19.7 4.4 7.4 7.9 3.1 2 1 0 2 2 2 0 Granulin amfpi-1 PF12190.3 EMD61464.1 - 7.5 7.1 14.2 0.54 10.7 5.3 2.2 2 0 0 2 2 2 0 Fungal protease inhibitor Sod_Cu PF00080.15 EMD61465.1 - 2.2e-14 53.8 0.0 3.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EMD61465.1 - 0.042 14.4 0.1 0.082 13.5 0.1 1.6 1 0 0 1 1 1 0 CHRD domain RRM_1 PF00076.17 EMD61466.1 - 1.7e-15 56.3 0.6 1.8e-08 33.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD61466.1 - 2.6e-11 43.3 0.1 9.4e-07 28.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD61466.1 - 4e-05 23.3 0.0 0.16 11.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4246 PF14033.1 EMD61466.1 - 0.016 13.8 1.1 0.017 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) NFRKB_winged PF14465.1 EMD61466.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NFRKB Winged Helix-like TRAM_LAG1_CLN8 PF03798.11 EMD61467.1 - 6e-46 156.5 11.7 6e-46 156.5 8.1 1.6 2 0 0 2 2 2 1 TLC domain PsbJ PF01788.12 EMD61467.1 - 0.041 13.4 2.2 0.87 9.1 0.0 2.7 2 0 0 2 2 2 0 PsbJ HIT PF01230.18 EMD61468.1 - 5.4e-18 65.3 0.1 9.3e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMD61468.1 - 2.2e-05 24.6 0.1 6.2e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Cyclin_N PF00134.18 EMD61470.1 - 2.3e-45 153.2 0.2 9e-44 148.0 0.2 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMD61470.1 - 6.5e-33 113.1 0.0 1.2e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ycf1 PF05758.7 EMD61470.1 - 0.53 7.9 3.4 0.62 7.7 2.4 1.2 1 0 0 1 1 1 0 Ycf1 Ribosomal_L2_C PF03947.13 EMD61471.1 - 3.2e-44 149.8 2.3 3.2e-44 149.8 1.6 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMD61471.1 - 2.1e-27 94.9 1.0 2.1e-27 94.9 0.7 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.13 EMD61472.1 - 2.5e-22 79.0 0.1 5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61472.1 - 1.4e-08 34.4 11.3 1.4e-08 34.4 7.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIM PF00412.17 EMD61473.1 - 1.1e-26 92.6 28.8 2.4e-10 40.3 1.4 3.8 4 0 0 4 4 4 3 LIM domain PHD PF00628.24 EMD61474.1 - 1.2e-08 34.5 10.4 3.1e-08 33.1 7.2 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMD61474.1 - 4.7e-05 22.6 3.1 4.7e-05 22.6 2.1 2.2 2 0 0 2 2 2 1 PHD-finger Ion_trans PF00520.26 EMD61475.1 - 6.4e-111 368.3 77.3 1.8e-38 131.8 2.2 5.3 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 EMD61475.1 - 0.0019 17.3 0.0 0.0049 16.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMD61475.1 - 0.081 12.8 0.0 0.36 10.8 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain Baculo_VP91_N PF08475.5 EMD61475.1 - 2.9 7.2 4.5 3.9 6.8 0.1 2.8 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal THRAP3_BCLAF1 PF15440.1 EMD61477.1 - 1.1 7.8 6.8 1.4 7.4 4.7 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Myb_Cef PF11831.3 EMD61478.1 - 4.6e-57 192.9 8.3 4.6e-57 192.9 5.7 3.8 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EMD61478.1 - 9.7e-19 67.1 2.0 2.2e-10 40.4 0.3 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD61478.1 - 3.9e-14 52.4 5.7 2.2e-09 37.2 2.9 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EMD61478.1 - 0.026 14.0 2.4 0.29 10.7 0.0 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1053 PF06327.9 EMD61479.1 - 0.06 13.7 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF515 PF04415.7 EMD61479.1 - 0.12 10.5 0.4 0.13 10.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) OB_NTP_bind PF07717.11 EMD61481.1 - 7.6e-27 93.4 0.0 1.7e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMD61481.1 - 1.4e-22 79.6 0.1 3.4e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMD61481.1 - 8.4e-11 41.5 0.0 2.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD61481.1 - 1e-06 28.3 0.3 3.1e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMD61481.1 - 3.1e-06 27.3 0.1 1.5e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMD61481.1 - 0.00032 20.1 0.1 0.00094 18.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EMD61481.1 - 0.0035 17.2 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EMD61481.1 - 0.0063 15.4 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EMD61481.1 - 0.011 15.4 0.6 0.023 14.4 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_23 PF13476.1 EMD61481.1 - 0.049 13.9 0.3 0.39 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMD61481.1 - 0.097 12.6 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain PRMT5 PF05185.11 EMD61482.1 - 8.9e-172 572.0 0.0 1.1e-171 571.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Brix PF04427.13 EMD61483.1 - 2.2e-47 161.2 0.1 2.6e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF3446 PF11928.3 EMD61486.1 - 2.8 8.2 7.3 16 5.8 5.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) ORC6 PF05460.8 EMD61487.1 - 1.9e-40 139.0 10.9 3.6e-39 134.8 7.6 2.1 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Med3 PF11593.3 EMD61487.1 - 0.46 9.6 4.1 0.75 8.9 2.9 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal p450 PF00067.17 EMD61489.1 - 2.6e-57 194.3 0.0 3.2e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UNC45-central PF11701.3 EMD61490.1 - 4.2e-35 120.7 6.6 5.2e-35 120.4 1.0 3.4 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EMD61490.1 - 2.1e-05 24.7 7.9 0.016 15.4 0.3 6.0 3 1 3 6 6 6 3 HEAT repeats Arm PF00514.18 EMD61490.1 - 0.0071 16.1 0.9 0.0071 16.1 0.6 6.7 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 EMD61491.1 - 1e-25 88.8 34.8 9.2e-07 28.3 0.2 8.2 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD61491.1 - 5.7e-17 61.2 39.3 4.9e-05 22.9 1.5 6.2 3 2 3 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 EMD61491.1 - 6.4e-07 29.0 17.2 0.0023 17.5 0.2 5.0 2 1 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.1 EMD61491.1 - 2.1e-05 24.1 32.4 0.28 11.3 0.0 10.1 10 1 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 EMD61491.1 - 3.2e-05 23.3 34.7 1.9 8.8 0.1 10.8 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 EMD61491.1 - 0.0037 17.1 31.7 15 6.3 0.0 11.2 13 1 1 14 14 14 2 Leucine rich repeat IPK PF03770.11 EMD61493.1 - 6.7e-58 195.5 0.0 1.5e-57 194.4 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase DHO_dh PF01180.16 EMD61494.1 - 1.3e-16 60.4 0.1 6.9e-08 31.7 0.9 2.1 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase EHN PF06441.7 EMD61496.1 - 3.2e-37 126.8 2.3 7.4e-37 125.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMD61496.1 - 1.2e-09 38.3 3.3 3.7e-09 36.8 2.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD61496.1 - 0.00073 19.1 0.3 0.0023 17.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DICT PF10069.4 EMD61496.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems Aminotran_3 PF00202.16 EMD61497.1 - 5.2e-35 120.8 0.1 1.3e-34 119.6 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.14 EMD61497.1 - 0.025 13.3 0.0 0.16 10.6 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class-V DUF3015 PF11220.3 EMD61497.1 - 0.032 13.8 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) MMgT PF10270.4 EMD61499.1 - 4.3e-30 104.2 0.0 5.1e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Toxin_45 PF15524.1 EMD61499.1 - 0.097 12.8 0.5 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 Putative toxin 45 FAD_binding_3 PF01494.14 EMD61500.1 - 1.5e-09 37.4 0.0 2.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_35 PF01301.14 EMD61501.1 - 1.9e-88 296.8 0.0 3.2e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EMD61501.1 - 2.9e-53 179.9 4.4 6.4e-53 178.8 3.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EMD61501.1 - 1.9e-48 163.3 8.3 1.4e-26 92.9 2.9 3.1 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EMD61501.1 - 3.5e-23 80.7 0.2 1e-21 76.1 0.0 2.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Fungal_trans PF04082.13 EMD61503.1 - 4.6e-17 61.7 0.1 7.8e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61503.1 - 0.033 14.1 11.7 0.064 13.1 8.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMD61505.1 - 5.9e-14 52.3 0.2 8.4e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61505.1 - 6.2e-11 42.5 0.0 7.9e-11 42.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61505.1 - 0.0003 20.5 0.0 0.00049 19.8 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF460 PF04312.8 EMD61505.1 - 0.002 17.6 0.1 0.0033 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) NmrA PF05368.8 EMD61505.1 - 0.042 13.0 0.1 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.12 EMD61505.1 - 0.06 13.7 0.1 0.5 10.8 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CHORD PF04968.7 EMD61506.1 - 2.5e-53 178.1 19.6 1.8e-27 95.3 3.2 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 EMD61506.1 - 1.1e-15 57.9 0.1 1.7e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EMD61507.1 - 8.1e-13 48.4 0.0 9.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EMD61507.1 - 0.0081 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin RicinB_lectin_2 PF14200.1 EMD61508.1 - 1.2e-10 41.6 0.0 6.6e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EMD61508.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain HpcH_HpaI PF03328.9 EMD61509.1 - 2.5e-29 101.7 0.0 3.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DSPc PF00782.15 EMD61509.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2156 PF09924.4 EMD61509.1 - 0.018 13.8 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) IGPS PF00218.16 EMD61509.1 - 0.078 12.0 0.1 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Asparaginase_2 PF01112.13 EMD61510.1 - 2.4e-38 131.6 3.4 3.9e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase MBT PF02820.13 EMD61510.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 mbt repeat Actin PF00022.14 EMD61511.1 - 8.4e-90 301.0 0.0 1.8e-89 299.9 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMD61511.1 - 6.3e-05 21.7 0.0 0.0074 14.9 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein DUF829 PF05705.9 EMD61511.1 - 0.2 11.3 0.0 0.45 10.1 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) tRNA_U5-meth_tr PF05958.6 EMD61512.1 - 6.7e-14 51.3 0.0 6e-13 48.2 0.0 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EMD61512.1 - 5.9e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EMD61512.1 - 1.3e-05 24.8 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD61512.1 - 0.00041 20.3 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMD61512.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRM PF02005.11 EMD61512.1 - 0.0055 15.6 0.2 0.059 12.2 0.0 2.0 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EMD61512.1 - 0.0066 17.0 0.0 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 EMD61512.1 - 0.0083 15.8 0.1 0.025 14.3 0.1 1.8 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 EMD61512.1 - 0.0089 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMD61512.1 - 0.056 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EMD61512.1 - 0.076 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S5_C PF03719.10 EMD61513.1 - 8.7e-18 63.3 0.0 1.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EMD61513.1 - 4.4e-08 32.7 0.1 1.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 EMD61514.1 - 7e-27 92.9 0.3 7.9e-27 92.7 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 EMD61515.1 - 1.3e-69 234.2 0.0 2.3e-69 233.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61515.1 - 9.8e-31 106.7 0.0 2.1e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMD61515.1 - 3.8e-06 26.0 0.2 0.039 12.9 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EMD61515.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mre11_DNA_bind PF04152.9 EMD61518.1 - 4.1e-55 186.3 2.9 4.1e-55 186.3 2.0 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EMD61518.1 - 3.9e-28 98.2 2.6 6e-28 97.6 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD61518.1 - 2.5e-06 27.4 0.6 7e-06 25.9 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RhoGAP PF00620.22 EMD61518.1 - 0.071 12.7 2.5 1.4 8.4 0.5 2.4 2 0 0 2 2 2 0 RhoGAP domain Ribosomal_S19 PF00203.16 EMD61519.1 - 2.2e-23 81.6 0.0 2.8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EMD61520.1 - 1.1e-23 82.8 0.2 1.8e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Cohesin_load PF10345.4 EMD61521.1 - 0.054 11.7 0.2 0.085 11.0 0.1 1.2 1 0 0 1 1 1 0 Cohesin loading factor F-box-like_2 PF13013.1 EMD61521.1 - 0.75 9.5 4.8 2.8 7.7 3.3 2.0 1 1 0 1 1 1 0 F-box-like domain La PF05383.12 EMD61522.1 - 1.3e-19 69.6 0.1 2.4e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 La domain MFS_1 PF07690.11 EMD61524.1 - 7.3e-26 90.7 45.2 2.4e-15 56.0 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD61524.1 - 4.5e-07 28.6 23.2 2e-06 26.5 6.6 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein PAM2 PF07145.10 EMD61525.1 - 1.4 8.6 19.8 0.061 12.8 0.4 5.0 4 1 1 5 5 5 0 Ataxin-2 C-terminal region SET PF00856.23 EMD61526.1 - 4.2e-27 95.4 0.2 8.6e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 EMD61526.1 - 1.6e-17 63.6 3.7 1.6e-17 63.6 2.5 2.2 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 EMD61526.1 - 0.0076 15.9 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nop52 PF05997.7 EMD61527.1 - 2.5e-67 226.4 2.4 2.9e-67 226.2 1.7 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3554 PF12074.3 EMD61527.1 - 0.022 14.2 0.5 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) TAN PF11640.3 EMD61527.1 - 0.03 14.0 0.2 0.082 12.6 0.1 1.8 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair HEAT PF02985.17 EMD61527.1 - 0.076 13.1 0.3 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 HEAT repeat zf-BED PF02892.10 EMD61529.1 - 0.0022 17.6 0.2 0.0022 17.6 0.1 2.2 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 EMD61529.1 - 0.0069 16.2 7.8 0.018 14.9 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.16 EMD61530.1 - 2.3e-25 88.9 17.4 2.3e-25 88.9 12.1 1.6 1 1 1 2 2 2 1 Snf7 7TMR-HDED PF07697.6 EMD61530.1 - 0.0011 18.7 10.5 0.0049 16.6 7.3 1.9 1 1 0 1 1 1 1 7TM-HD extracellular DUF1704 PF08014.6 EMD61530.1 - 0.012 14.6 1.6 0.019 13.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Terminase_4 PF05119.7 EMD61530.1 - 0.016 15.3 0.7 7.5 6.7 0.0 2.4 2 1 0 2 2 2 0 Phage terminase, small subunit TMPIT PF07851.8 EMD61530.1 - 0.12 11.4 3.3 0.18 10.8 2.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 EMD61530.1 - 0.16 10.9 15.0 0.012 14.5 6.9 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 EMD61530.1 - 0.19 11.7 21.8 0.11 12.4 9.6 2.4 2 1 0 2 2 2 0 YlqD protein AKNA PF12443.3 EMD61530.1 - 0.48 10.4 8.3 0.12 12.4 2.9 2.1 2 2 0 2 2 2 0 AT-hook-containing transcription factor DUF3573 PF12097.3 EMD61530.1 - 0.84 8.1 3.3 1.3 7.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF342 PF03961.8 EMD61530.1 - 1.3 7.3 11.4 1.3 7.4 5.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) GAS PF13851.1 EMD61530.1 - 1.5 7.9 17.9 0.037 13.2 6.7 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding MerR-DNA-bind PF09278.6 EMD61530.1 - 3.4 8.1 14.6 0.24 11.7 0.3 3.6 4 0 0 4 4 3 0 MerR, DNA binding L31 PF09784.4 EMD61530.1 - 3.5 7.7 9.3 0.8 9.8 3.7 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Allexi_40kDa PF05549.6 EMD61530.1 - 3.8 6.7 9.0 1.9 7.6 3.6 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein CS PF04969.11 EMD61531.1 - 8.4e-10 39.0 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 EMD61531.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Fork_head_N PF08430.7 EMD61531.1 - 0.094 13.1 6.9 0.14 12.5 4.8 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.6 EMD61531.1 - 5.7 4.6 7.1 8.3 4.1 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HAD_2 PF13419.1 EMD61532.1 - 1e-18 68.1 0.0 3.1e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD61532.1 - 5.4e-09 36.7 0.0 2e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD61532.1 - 1.7e-05 24.3 0.0 5.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMD61532.1 - 0.00048 19.9 0.0 0.0063 16.3 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EMD61532.1 - 0.018 14.5 0.0 0.056 12.9 0.0 1.8 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_11 PF13414.1 EMD61533.1 - 3.3e-13 49.0 3.9 4.5e-13 48.6 1.5 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMD61533.1 - 1.3e-08 34.0 1.7 0.0038 16.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61533.1 - 7.6e-07 28.9 2.8 7.6e-07 28.9 1.9 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD61533.1 - 7.1e-06 25.5 3.9 0.072 13.0 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD61533.1 - 0.00015 21.2 0.0 0.038 13.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD61533.1 - 0.0012 18.9 0.6 0.0027 17.8 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 YlbE PF14003.1 EMD61533.1 - 0.007 16.4 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 YlbE-like protein TPR_19 PF14559.1 EMD61533.1 - 0.0078 16.5 2.9 0.018 15.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61533.1 - 0.023 15.2 4.6 0.42 11.3 0.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61533.1 - 0.048 13.4 0.4 7.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB7 PF09486.5 EMD61533.1 - 0.3 10.9 3.8 4.6 7.1 0.1 2.7 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) MIT PF04212.13 EMD61533.1 - 0.61 10.0 4.2 0.76 9.6 1.1 2.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain p450 PF00067.17 EMD61535.1 - 4.7e-23 81.4 0.0 5.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.14 EMD61535.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain UPF0020 PF01170.13 EMD61536.1 - 1.4e-12 47.5 0.0 3.2e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMD61536.1 - 2.6e-08 33.9 0.0 6.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Lipase_GDSL_2 PF13472.1 EMD61537.1 - 4.3e-17 62.8 3.7 5.7e-17 62.4 2.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Rhomboid PF01694.17 EMD61538.1 - 1.2e-18 67.5 5.6 2.8e-18 66.3 3.9 1.5 1 0 0 1 1 1 1 Rhomboid family DUF2322 PF10084.4 EMD61538.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Abi PF02517.11 EMD61538.1 - 0.041 14.0 1.8 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 CAAX protease self-immunity PRA1 PF03208.14 EMD61538.1 - 0.28 10.4 2.6 0.34 10.2 0.3 2.1 2 0 0 2 2 2 0 PRA1 family protein MAP7 PF05672.6 EMD61538.1 - 5 6.4 29.3 17 4.7 20.3 1.8 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family PI-PLC-X PF00388.14 EMD61539.1 - 1e-11 44.4 0.0 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SIR2 PF02146.12 EMD61540.1 - 4.8e-26 91.5 0.0 1.5e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 EMD61541.1 - 3.4e-158 527.9 0.2 4.1e-158 527.6 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 YchF-GTPase_C PF06071.8 EMD61542.1 - 1.1e-32 111.6 0.4 2.3e-32 110.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EMD61542.1 - 2.8e-12 46.6 0.0 6.3e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD61542.1 - 0.00049 19.4 0.0 0.0017 17.6 0.0 1.9 2 1 1 3 3 3 1 Ferrous iron transport protein B TGS PF02824.16 EMD61542.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.18 EMD61542.1 - 0.012 15.4 0.0 0.32 10.7 0.0 2.7 2 1 0 3 3 3 0 Dynamin family AAA_14 PF13173.1 EMD61542.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD61542.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMD61542.1 - 0.092 13.0 3.5 0.77 10.0 2.5 2.3 1 1 0 1 1 1 0 AAA domain SecA_PP_bind PF01043.15 EMD61542.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.9 1 1 0 1 1 1 0 SecA preprotein cross-linking domain MobB PF03205.9 EMD61542.1 - 0.16 11.6 1.4 3 7.5 0.1 2.6 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_C97 PF05903.9 EMD61543.1 - 7.7e-30 103.6 0.0 9.9e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EMD61543.1 - 9.1e-05 22.4 0.1 0.00021 21.2 0.0 1.6 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF778 PF05608.7 EMD61543.1 - 0.034 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.14 EMD61544.1 - 3.3e-08 33.6 0.0 6.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 EMD61545.1 - 1.7e-33 115.6 0.0 3.3e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain Sec62 PF03839.11 EMD61545.1 - 8 5.8 6.7 15 4.9 4.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 4HBT PF03061.17 EMD61546.1 - 5e-11 42.5 0.0 8.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily FAD_binding_3 PF01494.14 EMD61547.1 - 8.2e-76 255.3 0.0 1e-75 255.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMD61547.1 - 4.7e-39 133.7 0.0 7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EMD61547.1 - 2.5e-05 23.3 0.1 0.0026 16.7 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD61547.1 - 0.00053 20.3 0.0 0.0027 18.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD61547.1 - 0.00091 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD61547.1 - 0.0058 15.7 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMD61547.1 - 0.014 15.2 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD61547.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.1 EMD61547.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.11 EMD61547.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EMD61547.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDI PF00996.13 EMD61547.1 - 0.047 11.9 0.0 0.072 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor zf-CCCH PF00642.19 EMD61549.1 - 2.7e-06 26.9 1.9 2.7e-06 26.9 1.3 2.6 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ost4 PF10215.4 EMD61550.1 - 6.2e-19 67.1 2.0 7.2e-19 66.9 1.4 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase KOW PF00467.24 EMD61552.1 - 1.4e-05 24.6 0.8 2.9e-05 23.6 0.5 1.6 1 0 0 1 1 1 1 KOW motif Kelch_5 PF13854.1 EMD61553.1 - 0.0027 17.5 0.2 2.4 8.2 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Rifin_STEVOR PF02009.11 EMD61553.1 - 0.0071 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family DcuC PF03606.10 EMD61553.1 - 0.053 11.7 0.2 0.079 11.1 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Kelch_3 PF13415.1 EMD61553.1 - 0.59 10.3 6.9 0.96 9.6 0.2 4.7 6 1 0 6 6 6 0 Galactose oxidase, central domain G-patch PF01585.18 EMD61555.1 - 0.0012 18.6 0.3 0.0026 17.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.20 EMD61556.1 - 2.7e-14 53.4 0.0 1.6e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD61556.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD61556.1 - 0.0015 18.5 0.1 0.0029 17.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD61556.1 - 0.0025 17.0 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMD61556.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neisseria_TspB PF05616.8 EMD61557.1 - 7.9 4.7 6.9 9.9 4.3 4.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Pyr_redox_2 PF07992.9 EMD61558.1 - 1.7e-17 64.0 0.1 2.3e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD61558.1 - 0.00026 19.5 0.0 0.00068 18.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EMD61558.1 - 0.00046 19.1 3.1 0.0005 19.0 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EMD61558.1 - 0.0017 17.2 1.2 0.073 11.9 0.1 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMD61558.1 - 0.0033 17.5 0.0 0.096 12.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD61558.1 - 0.02 14.8 0.0 0.071 13.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD61558.1 - 0.027 13.3 1.1 0.15 10.9 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase ApbA_C PF08546.6 EMD61558.1 - 0.052 13.5 1.5 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal K_oxygenase PF13434.1 EMD61558.1 - 0.13 11.1 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 EMD61559.1 - 1.9e-24 86.0 45.7 3e-19 68.9 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferritin_2 PF13668.1 EMD61560.1 - 6.4e-41 139.5 2.1 9.5e-41 138.9 1.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain RNB PF00773.14 EMD61561.1 - 1e-85 287.8 0.0 3.7e-85 286.0 0.0 2.0 2 0 0 2 2 2 1 RNB domain Methyltransf_26 PF13659.1 EMD61562.1 - 1.4 8.9 4.4 11 6.0 3.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain DUF572 PF04502.8 EMD61562.1 - 1.7 7.7 28.5 2.4 7.2 19.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1675 PF07897.6 EMD61562.1 - 2.9 7.6 15.3 4.4 7.1 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SPX PF03105.14 EMD61562.1 - 4.2 7.0 18.2 8.4 6.0 12.6 1.4 1 0 0 1 1 1 0 SPX domain SAPS PF04499.10 EMD61562.1 - 7 5.1 10.8 9.5 4.7 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.4 EMD61562.1 - 8.1 4.5 26.9 11 4.1 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_gE PF02480.11 EMD61563.1 - 0.048 11.9 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTCB-BRCT PF12738.2 EMD61564.1 - 1.4e-28 98.4 0.2 1.7e-20 72.6 0.2 4.1 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.21 EMD61564.1 - 2.2e-27 94.9 0.1 8.9e-09 35.3 0.0 5.7 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain Abhydrolase_6 PF12697.2 EMD61565.1 - 2.4e-26 93.0 0.0 4.1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD61565.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD61565.1 - 4.3e-05 23.2 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EMD61565.1 - 0.049 12.7 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase PGAP1 PF07819.8 EMD61565.1 - 0.064 12.8 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.15 EMD61565.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Tocopherol_cycl PF14249.1 EMD61566.1 - 2.7e-05 23.0 1.1 0.00012 20.9 0.8 2.0 1 1 0 1 1 1 1 Tocopherol cyclase Gly_transf_sug PF04488.10 EMD61567.1 - 4.8e-08 33.3 0.0 1.2e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMD61567.1 - 0.0005 19.3 0.0 0.00093 18.4 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein DIT1_PvcA PF05141.7 EMD61568.1 - 3.3e-77 259.5 0.0 4.6e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Amidase PF01425.16 EMD61569.1 - 7e-36 124.0 1.2 3.3e-35 121.7 0.3 2.0 2 0 0 2 2 2 1 Amidase MFS_1 PF07690.11 EMD61570.1 - 3.8e-25 88.3 49.6 8.1e-24 83.9 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DIT1_PvcA PF05141.7 EMD61571.1 - 1.9e-61 207.8 0.0 2.3e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein EspA PF03433.8 EMD61572.1 - 0.15 11.4 0.3 0.28 10.6 0.2 1.3 1 0 0 1 1 1 0 EspA-like secreted protein Glyco_hydro_18 PF00704.23 EMD61573.1 - 5.3e-55 187.2 2.1 8.5e-55 186.5 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD61573.1 - 0.00013 21.8 8.7 0.00013 21.8 6.1 3.4 3 0 0 3 3 3 2 Chitin recognition protein Myc_N PF01056.13 EMD61573.1 - 0.033 13.3 0.1 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 EMD61573.1 - 1.9 6.2 12.1 4.8 4.9 8.2 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Chitin_bind_1 PF00187.14 EMD61575.1 - 0.0086 16.0 181.3 0.024 14.6 14.9 10.5 6 2 5 11 11 11 5 Chitin recognition protein LysM PF01476.15 EMD61575.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain Plug PF07715.10 EMD61576.1 - 1.4 9.3 6.1 9.9 6.5 0.0 2.5 2 1 0 3 3 3 0 TonB-dependent Receptor Plug Domain ApbA PF02558.11 EMD61579.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CorA PF01544.13 EMD61580.1 - 2.9e-16 59.3 0.4 3.8e-16 58.9 0.3 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 EMD61580.1 - 0.011 14.3 0.1 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stathmin PF00836.14 EMD61580.1 - 0.026 14.1 0.2 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Stathmin family RXT2_N PF08595.6 EMD61580.1 - 0.032 14.0 0.8 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Picorna_P3A PF06363.6 EMD61580.1 - 0.088 12.8 0.7 0.42 10.6 0.3 2.1 1 1 1 2 2 2 0 Picornaviridae P3A protein P3A PF08727.6 EMD61580.1 - 0.15 11.4 0.7 0.63 9.4 0.4 2.2 2 1 0 2 2 2 0 Poliovirus 3A protein like DUF2306 PF10067.4 EMD61581.1 - 3.2e-09 36.8 9.0 3.2e-09 36.8 6.2 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Transp_cyt_pur PF02133.10 EMD61582.1 - 2.7e-24 85.5 40.2 4.9e-24 84.6 27.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.13 EMD61582.1 - 7e-05 21.7 18.8 7e-05 21.7 13.0 2.4 1 1 0 2 2 2 2 Natural resistance-associated macrophage protein Beta_elim_lyase PF01212.16 EMD61583.1 - 7.6e-55 186.1 0.0 1e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD61583.1 - 0.00037 19.6 0.2 0.001 18.2 0.1 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMD61583.1 - 0.002 17.1 0.1 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD61583.1 - 0.016 13.5 0.0 0.023 13.0 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BTB PF00651.26 EMD61587.1 - 2.3e-05 24.3 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M9_N PF08453.5 EMD61588.1 - 0.028 13.7 0.5 0.075 12.3 0.4 1.7 1 0 0 1 1 1 0 Peptidase family M9 N-terminal AAA_23 PF13476.1 EMD61588.1 - 5.4 7.2 11.2 1.3 9.2 0.3 2.5 2 0 0 2 2 2 0 AAA domain Band_7 PF01145.20 EMD61588.1 - 7.8 6.3 9.7 6.6 6.6 4.5 2.3 2 0 0 2 2 2 0 SPFH domain / Band 7 family FadA PF09403.5 EMD61589.1 - 0.0031 17.5 0.5 0.0031 17.5 0.4 2.3 3 0 0 3 3 3 1 Adhesion protein FadA Glyco_hydro_67N PF03648.9 EMD61589.1 - 0.0076 16.2 0.2 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DUF1980 PF09323.5 EMD61589.1 - 0.013 15.2 0.6 0.021 14.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) IncA PF04156.9 EMD61589.1 - 0.014 15.0 2.6 0.014 15.0 1.8 3.2 2 1 1 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 EMD61589.1 - 0.03 14.1 13.0 0.076 12.8 0.1 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EMD61589.1 - 0.23 10.4 14.6 0.36 9.8 2.0 3.0 3 0 0 3 3 3 0 Autophagy protein Apg6 Tho2 PF11262.3 EMD61589.1 - 0.25 10.3 5.0 2.4 7.1 0.4 2.9 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.1 EMD61589.1 - 0.42 9.7 13.1 0.13 11.4 0.5 3.3 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.1 EMD61589.1 - 0.71 10.0 12.2 0.24 11.5 0.4 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 EMD61589.1 - 1.3 9.0 13.3 2.2 8.3 2.3 3.3 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 EMD61589.1 - 1.4 8.7 12.1 1.9 8.3 2.7 3.2 3 0 0 3 3 3 0 Tropomyosin like DUF3158 PF11358.3 EMD61589.1 - 2.5 7.5 6.5 0.63 9.5 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3158) YlqD PF11068.3 EMD61589.1 - 3 7.9 10.9 0.43 10.6 1.8 2.9 3 0 0 3 3 3 0 YlqD protein Cep57_MT_bd PF06657.8 EMD61589.1 - 4.9 7.1 13.7 22 5.0 0.0 4.7 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Pkinase PF00069.20 EMD61590.1 - 0.00029 20.0 0.0 0.00031 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EMD61591.1 - 8.2e-15 54.9 0.7 3.3e-05 24.1 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD61591.1 - 3.1e-13 49.8 3.4 2.1e-05 24.8 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD61591.1 - 4.5e-11 42.6 5.8 3.8e-06 26.9 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD61591.1 - 1e-09 37.6 2.5 0.0073 16.4 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 EMD61591.1 - 4.7e-08 32.4 6.8 0.0004 20.0 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeat DUF1193 PF06702.7 EMD61591.1 - 0.073 12.4 0.2 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) GFA PF04828.9 EMD61592.1 - 4.4e-19 68.2 0.1 6.3e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EMD61592.1 - 0.21 11.4 2.1 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SNF2_N PF00176.18 EMD61593.1 - 2.7e-24 85.5 0.0 9.7e-24 83.6 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD61593.1 - 3.8e-09 36.2 0.0 9.9e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2570 PF10828.3 EMD61594.1 - 0.052 13.1 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF3435 PF11917.3 EMD61597.1 - 0.00053 18.8 0.0 0.00087 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EMD61597.1 - 0.052 13.2 0.1 0.2 11.2 0.0 2.0 3 0 0 3 3 3 0 Phage integrase family zf-Di19 PF05605.7 EMD61597.1 - 0.095 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1768 PF08719.6 EMD61598.1 - 5.1e-37 127.0 0.0 5.9e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) AlaDh_PNT_N PF05222.10 EMD61598.1 - 0.072 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Arginase PF00491.16 EMD61599.1 - 2.6e-93 312.3 0.0 3.1e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMD61599.1 - 0.0059 16.8 0.5 0.021 15.0 0.1 2.0 2 0 0 2 2 2 1 UPF0489 domain Fapy_DNA_glyco PF01149.19 EMD61600.1 - 9.2e-27 93.7 0.0 2.2e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EMD61600.1 - 7e-21 73.7 0.0 1.6e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain NARP1 PF12569.3 EMD61601.1 - 5.5e-209 695.2 24.8 5.5e-209 695.2 17.2 2.5 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EMD61601.1 - 3.2e-21 75.4 22.9 4.9e-05 23.5 0.1 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61601.1 - 4.8e-18 65.3 15.8 2.9e-05 24.5 1.2 8.4 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61601.1 - 3.5e-17 61.8 24.3 0.00088 18.8 0.0 8.3 5 2 3 8 8 8 6 TPR repeat TPR_2 PF07719.12 EMD61601.1 - 7.5e-16 56.7 27.5 0.015 15.1 0.0 10.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61601.1 - 4e-14 51.8 15.0 2.1 9.2 0.0 10.7 7 3 4 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61601.1 - 3.3e-10 39.3 9.5 0.009 16.1 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61601.1 - 3.5e-09 35.7 7.4 3.6 7.5 0.0 7.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD61601.1 - 2e-08 33.5 26.1 0.0048 16.4 0.0 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD61601.1 - 2.9e-08 33.5 19.6 1.2 9.0 0.2 8.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMD61601.1 - 5.4e-08 32.5 14.4 0.055 13.3 0.0 6.2 5 1 2 7 7 6 3 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 EMD61601.1 - 1.2e-05 24.1 0.7 2.5e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fis1_TPR_C PF14853.1 EMD61601.1 - 0.00061 19.6 11.0 8 6.4 0.0 6.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Zn_clus PF00172.13 EMD61601.1 - 0.0013 18.5 2.0 0.0034 17.2 1.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_7 PF13176.1 EMD61601.1 - 0.0017 17.9 13.2 3.1 7.8 0.1 7.7 8 1 1 9 9 6 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMD61601.1 - 0.0018 18.5 4.6 0.55 10.4 0.2 3.5 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_4 PF07721.9 EMD61601.1 - 0.0033 17.7 0.9 1 10.0 0.0 3.8 2 0 0 2 2 2 1 Tetratricopeptide repeat PPTA PF01239.17 EMD61601.1 - 0.034 13.5 1.1 11 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.1 EMD61601.1 - 0.28 11.1 6.4 70 3.5 0.0 5.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Opy2 PF09463.5 EMD61601.1 - 0.31 11.1 1.9 0.68 10.0 1.3 1.5 1 0 0 1 1 1 0 Opy2 protein TPR_6 PF13174.1 EMD61601.1 - 0.42 11.1 20.8 25 5.6 0.4 8.6 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF716 PF04819.7 EMD61603.1 - 0.08 12.3 0.7 0.092 12.1 0.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF716) bZIP_1 PF00170.16 EMD61605.1 - 7.8e-06 25.7 7.0 1.2e-05 25.1 4.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD61605.1 - 0.0011 18.7 7.7 0.0016 18.2 5.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD61605.1 - 0.0073 16.5 2.3 0.012 15.9 1.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2477 PF10631.4 EMD61605.1 - 8 6.6 7.2 1.7 8.8 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) AAA PF00004.24 EMD61606.1 - 2.7e-14 53.5 0.0 4.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD61606.1 - 3.6e-12 46.6 0.2 3.6e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD61606.1 - 1.4e-08 34.9 0.0 1.4e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 EMD61606.1 - 3.5e-08 33.1 0.1 8.3e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 EMD61606.1 - 0.00022 20.9 0.1 0.00075 19.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMD61606.1 - 0.0012 19.6 0.0 0.0077 17.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain Bac_globin PF01152.16 EMD61606.1 - 0.0032 17.4 0.1 0.13 12.2 0.0 2.7 3 0 0 3 3 3 1 Bacterial-like globin NACHT PF05729.7 EMD61606.1 - 0.0036 16.9 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 EMD61606.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMD61606.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EMD61606.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD61606.1 - 0.016 14.9 0.0 0.2 11.3 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_32 PF13654.1 EMD61606.1 - 0.018 13.7 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD61606.1 - 0.041 14.2 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EMD61606.1 - 0.046 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 EMD61606.1 - 0.078 11.9 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EMD61606.1 - 0.11 12.6 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 1 0 RNA helicase UvrD-helicase PF00580.16 EMD61606.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DDHD PF02862.12 EMD61607.1 - 7.9e-45 153.4 2.4 1.5e-26 93.6 0.0 2.9 3 1 1 4 4 4 2 DDHD domain Abhydrolase_5 PF12695.2 EMD61607.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD61607.1 - 0.016 15.1 0.0 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Aldedh PF00171.17 EMD61608.1 - 3.8e-186 618.9 0.9 4.2e-186 618.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD61608.1 - 0.00055 19.2 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RRM_1 PF00076.17 EMD61609.1 - 2.5e-10 39.8 0.0 4.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD61609.1 - 3.8e-09 36.4 0.0 6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMD61609.1 - 5.5e-07 29.9 4.5 5.5e-07 29.9 3.1 2.8 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EMD61609.1 - 0.00088 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Clathrin PF00637.15 EMD61610.1 - 6.4e-22 77.6 3.6 3.9e-20 71.9 1.9 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EMD61610.1 - 1.9e-19 69.2 0.0 5.2e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EMD61610.1 - 2.3e-05 24.0 6.7 4.2e-05 23.1 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMD61610.1 - 0.0002 21.1 8.2 0.00038 20.2 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD61610.1 - 0.00047 20.1 7.2 0.00088 19.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps8 PF12816.2 EMD61610.1 - 0.0084 15.3 0.4 0.056 12.6 0.0 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-C3HC4_3 PF13920.1 EMD61610.1 - 0.011 15.3 5.9 0.02 14.5 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD61610.1 - 0.033 14.0 2.2 0.075 12.8 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMD61610.1 - 0.04 13.7 7.4 0.077 12.8 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMD61610.1 - 0.044 13.4 7.8 0.084 12.5 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD61610.1 - 0.052 13.6 3.0 0.11 12.6 2.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_14 PF13428.1 EMD61610.1 - 0.099 13.3 0.1 14 6.6 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61610.1 - 0.1 12.2 2.0 0.19 11.4 0.0 2.5 3 0 0 3 3 2 0 TPR repeat HypA PF01155.14 EMD61610.1 - 0.23 11.1 4.4 0.9 9.2 3.1 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-Nse PF11789.3 EMD61610.1 - 0.32 10.5 4.3 0.74 9.3 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.1 EMD61610.1 - 1.3 8.7 5.3 1.8 8.3 2.5 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-MIZ PF02891.15 EMD61610.1 - 1.8 8.1 6.0 3.8 7.1 4.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD PF00628.24 EMD61610.1 - 2.2 8.0 7.2 4.3 7.1 5.0 1.5 1 0 0 1 1 1 0 PHD-finger PXA PF02194.10 EMD61611.1 - 4.5e-49 166.5 1.3 4.8e-48 163.1 0.0 3.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EMD61611.1 - 3.9e-24 84.8 0.1 3.9e-24 84.8 0.1 2.4 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EMD61611.1 - 9.8e-21 73.6 0.2 2.3e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EMD61611.1 - 5.2e-12 45.9 0.1 1.5e-11 44.4 0.1 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain CFEM PF05730.6 EMD61613.1 - 3.1e-14 52.5 10.7 6e-14 51.6 7.4 1.5 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.6 EMD61613.1 - 2.2 6.3 9.9 3 5.8 6.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.27 EMD61615.1 - 6.4e-51 168.5 14.7 6.8e-10 38.4 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMD61615.1 - 0.00047 18.4 1.4 2.9 5.9 0.1 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMD61615.1 - 0.0044 16.5 0.2 0.25 10.7 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EMD61615.1 - 0.013 14.2 0.3 0.92 8.1 0.1 3.1 1 1 1 3 3 3 0 Nup133 N terminal like ABC_tran_2 PF12848.2 EMD61615.1 - 0.56 10.0 4.8 1.2 9.0 3.3 1.5 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EMD61616.1 - 1.4e-20 73.8 0.4 3.4e-20 72.6 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EMD61616.1 - 1.1e-19 70.5 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD61616.1 - 0.00057 19.5 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMD61616.1 - 0.00086 18.9 0.2 0.094 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EMD61616.1 - 0.0073 16.1 0.3 0.027 14.2 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMD61616.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 EMD61616.1 - 0.072 13.2 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain adh_short PF00106.20 EMD61617.1 - 3.5e-25 88.8 4.7 5e-25 88.3 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61617.1 - 1.8e-19 70.4 1.1 2.2e-19 70.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61617.1 - 6.2e-11 42.2 2.8 1.1e-10 41.4 1.9 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMD61617.1 - 0.054 12.1 0.2 0.2 10.3 0.1 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4332 PF14229.1 EMD61617.1 - 0.067 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) 3HCDH_N PF02737.13 EMD61617.1 - 0.093 12.3 0.2 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HCV_NS1 PF01560.12 EMD61617.1 - 0.095 11.1 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Methyltransf_PK PF05891.7 EMD61617.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Epimerase PF01370.16 EMD61617.1 - 0.11 11.9 1.8 0.44 9.9 1.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Xan_ur_permease PF00860.15 EMD61619.1 - 5.6e-26 90.9 27.6 1.2e-25 89.7 17.3 2.5 1 1 1 2 2 2 1 Permease family DUF2834 PF11196.3 EMD61619.1 - 0.0017 18.4 3.8 0.0061 16.6 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2834) AhpC-TSA_2 PF13911.1 EMD61621.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMD61621.1 - 0.0055 16.3 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NAD_binding_8 PF13450.1 EMD61622.1 - 3.9e-13 49.2 0.1 1.2e-12 47.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD61622.1 - 9.1e-10 38.9 0.1 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD61622.1 - 1.4e-06 27.6 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EMD61622.1 - 2.3e-06 26.9 0.0 4.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD61622.1 - 9.7e-06 24.2 0.5 1.6e-05 23.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMD61622.1 - 3.3e-05 23.8 0.1 9.4e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD61622.1 - 7.8e-05 21.6 0.0 0.00032 19.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMD61622.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMD61622.1 - 0.0038 16.3 0.2 0.0059 15.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMD61622.1 - 0.0038 16.1 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD61622.1 - 0.0074 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DJ-1_PfpI PF01965.19 EMD61622.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Shikimate_DH PF01488.15 EMD61622.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EMD61622.1 - 0.043 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EMD61622.1 - 0.05 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMD61622.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EMD61622.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EMD61622.1 - 0.057 12.2 0.2 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pax7 PF12360.3 EMD61624.1 - 0.1 12.8 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Paired box protein 7 GMC_oxred_N PF00732.14 EMD61625.1 - 1.4e-20 73.6 0.1 1.2e-13 50.8 0.0 3.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD61625.1 - 3.3e-14 53.3 0.0 6.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EMD61625.1 - 0.029 14.4 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DeoRC PF00455.17 EMD61625.1 - 0.075 12.6 0.2 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 DeoR C terminal sensor domain Pyr_redox_2 PF07992.9 EMD61625.1 - 0.12 12.2 0.0 2.1 8.1 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Na_Ca_ex PF01699.19 EMD61626.1 - 0.0033 17.0 4.8 0.0033 17.0 3.3 2.0 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Glyco_hydro_88 PF07470.8 EMD61627.1 - 4.2e-63 213.4 7.9 5.8e-63 212.9 5.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DEAD PF00270.24 EMD61629.1 - 2.3e-44 150.8 0.0 4.6e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMD61629.1 - 4.1e-23 80.6 0.2 1e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMD61629.1 - 8.7e-22 76.7 0.0 2.8e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMD61629.1 - 0.0065 16.4 1.1 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain PAS_11 PF14598.1 EMD61629.1 - 0.041 13.8 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 PAS domain Coat_X PF07552.6 EMD61629.1 - 0.086 12.6 1.2 0.21 11.3 0.8 1.6 1 0 0 1 1 1 0 Spore Coat Protein X and V domain DnaJ PF00226.26 EMD61630.1 - 1.1e-13 50.7 0.6 1.1e-13 50.7 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain Suf PF05843.9 EMD61630.1 - 0.23 11.1 6.7 0.32 10.6 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CT47 PF15623.1 EMD61630.1 - 0.34 10.6 12.7 0.44 10.2 8.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Zn_clus PF00172.13 EMD61631.1 - 0.00016 21.5 11.6 0.00023 20.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PcF PF09461.5 EMD61632.1 - 0.032 14.1 1.1 0.063 13.1 0.3 1.9 2 0 0 2 2 2 0 Phytotoxin PcF protein DEAD PF00270.24 EMD61633.1 - 3.6e-45 153.4 0.0 8.6e-45 152.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61633.1 - 6.4e-25 86.8 0.1 8.3e-24 83.2 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EMD61633.1 - 8.8e-23 79.9 5.0 4e-22 77.7 3.5 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.6 EMD61634.1 - 2.8e-17 62.9 0.1 7.4e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EMD61634.1 - 5.3e-08 32.6 0.0 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain MarR_2 PF12802.2 EMD61634.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF202 PF02656.10 EMD61635.1 - 8.8e-18 64.2 1.0 8.8e-18 64.2 0.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EMD61635.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.5 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF4131 PF13567.1 EMD61635.1 - 2.2 7.6 6.7 1.7 8.0 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CIA30 PF08547.7 EMD61636.1 - 2.1e-37 128.4 0.2 3.4e-37 127.7 0.1 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Homeobox PF00046.24 EMD61637.1 - 1.9e-13 49.7 0.6 5.1e-13 48.4 0.4 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD61637.1 - 0.0082 15.8 0.1 0.032 13.9 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 EMD61638.1 - 7e-17 62.2 0.0 1.3e-16 61.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD61638.1 - 2.5e-11 44.3 0.0 4.4e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD61638.1 - 3.4e-06 26.6 0.0 6.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMD61638.1 - 7.6e-06 26.2 0.0 9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMD61638.1 - 0.0035 17.1 0.0 0.05 13.4 0.0 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD61638.1 - 0.06 12.9 0.0 0.2 11.1 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EMD61639.1 - 4.4e-25 87.3 16.5 1.2e-24 85.9 11.5 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EMD61639.1 - 2.2e-20 72.7 0.2 1.6e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMD61639.1 - 6.6e-06 26.0 9.2 0.039 13.7 2.4 4.1 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EMD61639.1 - 1.3e-05 24.7 0.0 0.024 14.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMD61639.1 - 1.7e-05 24.1 0.4 5.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMD61639.1 - 0.00034 19.8 0.2 0.00062 18.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EMD61639.1 - 0.0039 16.4 0.1 0.54 9.4 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMD61639.1 - 0.0057 17.1 0.6 0.61 10.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EMD61639.1 - 0.026 14.8 0.0 0.026 14.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain BUD22 PF09073.5 EMD61639.1 - 0.041 12.9 20.0 0.073 12.1 13.9 1.3 1 0 0 1 1 1 0 BUD22 ArgK PF03308.11 EMD61639.1 - 0.071 11.8 0.1 0.071 11.8 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 EMD61639.1 - 0.13 13.1 0.1 0.13 13.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Ebola_NP PF05505.7 EMD61639.1 - 0.14 10.2 12.9 0.2 9.6 9.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein AAA_16 PF13191.1 EMD61639.1 - 1.6 8.6 6.5 0.91 9.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EMD61639.1 - 1.7 8.9 8.9 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PI3K_1B_p101 PF10486.4 EMD61639.1 - 2.2 5.7 5.9 2.8 5.3 4.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Aldedh PF00171.17 EMD61640.1 - 6.9e-107 357.6 0.0 8.2e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 EMD61641.1 - 2.7e-37 128.2 42.4 2.7e-37 128.2 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0182 PF03699.8 EMD61641.1 - 0.16 9.8 0.4 0.32 8.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Glyco_hydro_47 PF01532.15 EMD61642.1 - 1.7e-154 514.8 0.0 1.9e-154 514.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Arrestin_N PF00339.24 EMD61643.1 - 2.5e-11 43.5 0.0 1.2e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 EMD61643.1 - 0.15 10.8 0.0 0.36 9.5 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Mito_carr PF00153.22 EMD61644.1 - 1.1e-54 182.0 2.0 4.6e-19 67.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gryzun PF07919.7 EMD61647.1 - 4e-136 454.5 0.1 5.1e-136 454.2 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EMD61647.1 - 9.5e-85 284.0 1.9 1.3e-77 260.6 1.7 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EMD61647.1 - 0.21 11.3 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking RXT2_N PF08595.6 EMD61648.1 - 2.8e-30 105.0 0.2 2.8e-30 105.0 0.1 3.5 4 1 1 5 5 5 1 RXT2-like, N-terminal RapA_C PF12137.3 EMD61648.1 - 7.7e-05 21.6 1.1 0.00015 20.7 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal IncA PF04156.9 EMD61648.1 - 0.014 15.0 2.1 0.035 13.6 1.5 1.6 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 EMD61648.1 - 0.17 11.7 0.7 0.41 10.5 0.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1366 PF07104.6 EMD61648.1 - 0.98 9.0 6.5 0.26 10.9 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Syntaxin PF00804.20 EMD61648.1 - 2.1 8.5 9.3 0.16 12.1 2.2 2.3 2 0 0 2 2 2 0 Syntaxin OmpH PF03938.9 EMD61648.1 - 2.6 7.9 13.5 0.37 10.7 6.0 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AATF-Che1 PF13339.1 EMD61648.1 - 8.7 6.5 16.9 0.6 10.2 1.8 3.8 4 0 0 4 4 4 0 Apoptosis antagonizing transcription factor zf-C2H2_4 PF13894.1 EMD61649.1 - 0.0009 19.4 11.7 0.1 13.0 2.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EMD61649.1 - 0.0022 17.7 10.5 0.012 15.3 0.3 2.4 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.1 EMD61649.1 - 0.0074 16.5 2.5 0.0074 16.5 1.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-CHCC PF10276.4 EMD61649.1 - 0.02 14.7 6.8 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.10 EMD61649.1 - 0.026 13.9 1.9 0.68 9.4 0.2 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.2 EMD61649.1 - 0.046 13.5 1.5 0.093 12.5 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon HNH PF01844.18 EMD61649.1 - 0.062 13.1 2.6 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 HNH endonuclease zf-FCS PF06467.9 EMD61649.1 - 0.6 9.8 5.3 0.64 9.7 0.7 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 EMD61649.1 - 1.5 9.0 7.2 13 6.0 5.0 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMD61649.1 - 1.6 8.9 7.4 4.6 7.4 2.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EMD61649.1 - 5.4 7.5 18.2 1.1 9.7 3.5 3.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type Aminotran_5 PF00266.14 EMD61651.1 - 1.2e-25 90.1 0.0 2.6e-25 88.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V zf-C2H2_4 PF13894.1 EMD61653.1 - 0.0012 18.9 3.4 0.31 11.4 0.2 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD61653.1 - 1.3 9.4 5.1 0.33 11.3 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phage_antitermQ PF06530.7 EMD61654.1 - 0.05 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q zf-BED PF02892.10 EMD61655.1 - 0.00096 18.8 2.1 0.68 9.7 0.1 2.7 2 0 0 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.1 EMD61655.1 - 0.008 16.4 0.2 0.008 16.4 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMD61655.1 - 0.011 15.9 1.0 0.011 15.9 0.7 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EMD61655.1 - 0.14 12.5 0.3 0.14 12.5 0.2 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD61655.1 - 0.37 10.7 3.5 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_3 PF07649.7 EMD61655.1 - 2.3 8.3 8.1 2.5 8.2 0.1 3.2 3 0 0 3 3 3 0 C1-like domain zf-C2H2_4 PF13894.1 EMD61655.1 - 3.1 8.3 14.3 0.95 9.9 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.2 EMD61657.1 - 0.00041 20.0 0.1 0.00078 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like MLANA PF14991.1 EMD61657.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A F-box PF00646.28 EMD61657.1 - 0.035 13.7 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain SprT-like PF10263.4 EMD61658.1 - 8.5e-29 100.2 0.1 1.5e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 SprT-like family PRP21_like_P PF12230.3 EMD61658.1 - 0.4 10.1 3.5 0.59 9.5 2.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein RabGAP-TBC PF00566.13 EMD61659.1 - 2.8e-48 164.2 0.1 4.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1411 PF07199.6 EMD61659.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) SNF2_N PF00176.18 EMD61660.1 - 8.8e-63 211.8 0.1 1.4e-62 211.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EMD61660.1 - 4.5e-22 77.4 6.6 2.6e-13 49.4 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMD61660.1 - 3.6e-14 52.3 0.0 8.9e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EMD61660.1 - 8.9e-09 35.4 0.5 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) DEAD PF00270.24 EMD61660.1 - 0.00046 19.7 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMD61660.1 - 0.046 13.8 0.1 0.29 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain Metallophos PF00149.23 EMD61662.1 - 3.6e-06 26.5 0.6 1.3e-05 24.6 0.4 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CorA PF01544.13 EMD61663.1 - 7.7e-06 25.1 5.5 5.5e-05 22.3 0.3 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF1604 PF07713.8 EMD61664.1 - 1.3e-38 130.6 1.8 4.1e-38 129.0 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EMD61664.1 - 0.00061 19.5 0.2 0.0021 17.8 0.1 2.0 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.20 EMD61665.1 - 3.7e-77 258.9 0.0 5.5e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61665.1 - 4.5e-40 137.3 0.1 1.2e-39 135.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EMD61665.1 - 6e-16 57.6 0.0 9.7e-16 56.9 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EMD61665.1 - 2.7e-05 23.2 0.0 0.00011 21.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMD61665.1 - 9.7e-05 21.5 0.1 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMD61665.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EMD61665.1 - 0.012 15.3 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMD61665.1 - 0.036 13.4 0.1 0.083 12.2 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Rcd1 PF04078.8 EMD61666.1 - 5.5e-131 435.1 2.8 6.6e-131 434.8 1.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DOR PF14839.1 EMD61666.1 - 7.7 6.2 9.7 14 5.3 6.7 1.3 1 0 0 1 1 1 0 DOR family Ribosomal_L1 PF00687.16 EMD61667.1 - 8.9e-54 182.1 0.9 1.1e-53 181.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 EMD61667.1 - 0.051 12.0 0.0 0.071 11.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Cid2 PF09774.4 EMD61668.1 - 1.6e-50 171.1 0.0 1.9e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DNA_ligase_A_M PF01068.16 EMD61669.1 - 1.8e-57 194.0 6.1 9.8e-47 158.9 0.3 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD61669.1 - 1.8e-53 180.9 0.1 3.4e-53 180.0 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMD61669.1 - 6.5e-28 96.9 1.4 1.3e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Zn_clus PF00172.13 EMD61671.1 - 1.8e-09 37.3 11.3 2.8e-09 36.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.3 EMD61673.1 - 3.8e-139 463.5 0.2 4.3e-139 463.3 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Med3 PF11593.3 EMD61673.1 - 0.21 10.7 2.6 0.35 10.0 1.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PUA PF01472.15 EMD61674.1 - 3.9e-15 55.3 0.0 1.2e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 PUA domain GST_N_3 PF13417.1 EMD61675.1 - 3.3e-26 91.3 0.1 6.9e-26 90.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD61675.1 - 4.5e-15 55.4 0.1 9.8e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD61675.1 - 5.6e-07 29.3 0.1 1.4e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD61675.1 - 4.1e-06 26.8 0.4 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain JAB PF01398.16 EMD61676.1 - 0.00029 20.5 0.0 0.0021 17.7 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EMD61676.1 - 0.19 10.9 4.7 0.26 10.4 0.7 2.5 2 1 1 3 3 3 0 Glycogen debranching enzyme N terminal SHS2_Rpb7-N PF03876.12 EMD61678.1 - 1.3e-07 31.5 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF423 PF04241.10 EMD61679.1 - 8.2e-22 76.9 3.0 1.3e-21 76.2 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Trep_Strep PF09605.5 EMD61679.1 - 0.0075 15.9 1.3 0.013 15.2 0.9 1.3 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1517 PF07466.6 EMD61679.1 - 0.15 10.9 0.5 0.18 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) p450 PF00067.17 EMD61680.1 - 1.5e-53 181.9 0.0 2.2e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-H2C2_2 PF13465.1 EMD61682.1 - 5.9e-07 29.4 0.8 5.9e-07 29.4 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD61682.1 - 1e-05 25.5 4.1 0.00013 22.0 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD61682.1 - 2.7e-05 24.2 0.4 2.7e-05 24.2 0.3 3.2 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD61682.1 - 0.024 14.5 0.1 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD61682.1 - 0.22 11.7 2.9 0.92 9.7 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMD61682.1 - 2.7 8.1 6.1 1.2e+02 2.8 0.1 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Aldo_ket_red PF00248.16 EMD61683.1 - 9e-66 221.5 0.0 1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ceramidase PF05875.7 EMD61684.1 - 4.5e-77 258.7 5.2 5.2e-77 258.5 3.6 1.0 1 0 0 1 1 1 1 Ceramidase VIT1 PF01988.14 EMD61684.1 - 0.0056 16.1 2.5 0.013 15.0 0.4 2.1 2 0 0 2 2 2 1 VIT family Leader_Trp PF08255.6 EMD61684.1 - 0.022 14.3 2.4 0.074 12.7 1.7 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Sugar_tr PF00083.19 EMD61685.1 - 6.4e-94 315.0 33.6 8e-94 314.7 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61685.1 - 4.2e-26 91.5 39.3 7.7e-21 74.1 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_5 PF13857.1 EMD61686.1 - 4.5e-16 58.5 1.1 1.3e-10 41.1 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.13 EMD61686.1 - 2.3e-15 56.4 0.0 6.1e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EMD61686.1 - 1.4e-09 38.1 0.1 3.9e-05 23.8 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD61686.1 - 1.8e-08 33.8 0.0 0.1 12.8 0.0 6.0 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 EMD61686.1 - 2.8e-06 26.8 1.3 0.0021 17.7 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 EMD61686.1 - 2e-05 24.9 0.0 0.0056 17.1 0.0 4.9 2 2 4 6 6 6 2 Ankyrin repeats (many copies) PX PF00787.19 EMD61686.1 - 5.9e-05 22.8 0.1 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 PX domain FAD_binding_4 PF01565.18 EMD61687.1 - 6.2e-20 71.0 1.2 1e-19 70.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD61687.1 - 6.1e-14 51.6 0.1 1.6e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like LRR_4 PF12799.2 EMD61688.1 - 0.063 12.9 0.3 6.8 6.4 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 EMD61689.1 - 9.9e-19 67.8 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD61689.1 - 1.9e-07 30.9 0.1 3.5e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD61689.1 - 1.2e-06 28.4 0.1 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EMD61689.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EMD61689.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EMD61689.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WSC PF01822.14 EMD61690.1 - 1.9e-16 59.7 6.2 2.2e-16 59.5 4.3 1.1 1 0 0 1 1 1 1 WSC domain PAN_1 PF00024.21 EMD61690.1 - 0.098 12.4 3.2 2.6 7.8 0.2 2.2 1 1 1 2 2 2 0 PAN domain Sas10 PF09368.5 EMD61691.1 - 3.9e-29 100.6 8.7 2.6e-28 98.0 6.0 2.5 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EMD61691.1 - 2.5e-10 40.3 0.0 1.2e-09 38.1 0.0 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family BOP1NT PF08145.7 EMD61692.1 - 3.9e-105 351.2 7.8 5.3e-105 350.8 5.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EMD61692.1 - 2.2e-27 93.9 0.8 1e-08 34.7 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat BetaGal_dom3 PF13363.1 EMD61692.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DEAD PF00270.24 EMD61693.1 - 2.2e-42 144.4 0.0 1.4e-40 138.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61693.1 - 1.1e-21 76.4 0.0 3.1e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMD61693.1 - 0.0011 18.0 0.0 0.0038 16.3 0.0 1.9 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EMD61693.1 - 0.044 13.6 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sld5 PF05916.6 EMD61694.1 - 8.5e-15 54.9 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EMD61694.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) HMG_box PF00505.14 EMD61695.1 - 3.3e-09 36.8 0.2 7.1e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box AflR PF08493.5 EMD61697.1 - 4.8e-11 42.2 7.2 3.5e-10 39.3 5.1 2.2 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EMD61697.1 - 1.2e-07 31.5 12.0 3.2e-07 30.1 8.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.16 EMD61699.1 - 8.8e-58 195.4 0.0 5.2e-57 192.9 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD61699.1 - 5.6e-19 68.7 0.1 1.1e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EMD61699.1 - 0.0014 18.7 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV DUF1073 PF06381.6 EMD61699.1 - 0.067 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) DAP3 PF10236.4 EMD61699.1 - 0.22 10.4 0.0 0.41 9.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_2 PF07724.9 EMD61700.1 - 2.3e-47 161.1 0.0 2.3e-45 154.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMD61700.1 - 2.9e-26 91.1 0.1 1.2e-25 89.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMD61700.1 - 1.9e-20 73.4 1.3 2.1e-11 44.1 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD61700.1 - 2.2e-13 50.1 0.0 4.2e-08 33.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD61700.1 - 2.6e-09 37.2 0.3 0.0029 17.7 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EMD61700.1 - 9.3e-09 35.5 11.2 0.0014 18.6 0.0 5.1 4 2 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.21 EMD61700.1 - 4.4e-08 32.7 0.2 9.2e-05 21.9 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EMD61700.1 - 8.4e-07 29.3 7.0 0.028 14.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 EMD61700.1 - 1.6e-06 28.0 0.3 0.022 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EMD61700.1 - 5.9e-06 27.0 8.6 0.0015 19.3 0.2 4.2 3 2 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EMD61700.1 - 1.4e-05 24.9 9.1 0.0077 15.9 0.4 4.5 3 1 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EMD61700.1 - 2.1e-05 24.1 0.0 0.035 13.8 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EMD61700.1 - 5.4e-05 22.9 0.0 0.038 13.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 EMD61700.1 - 0.00035 19.2 0.1 0.78 8.2 0.0 2.9 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EMD61700.1 - 0.00037 20.1 2.5 0.3 10.6 0.0 4.0 5 0 0 5 5 3 1 AAA domain IstB_IS21 PF01695.12 EMD61700.1 - 0.00039 19.8 0.2 0.24 10.8 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein SRP54 PF00448.17 EMD61700.1 - 0.00047 19.6 0.0 0.041 13.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 EMD61700.1 - 0.00064 19.4 0.0 0.36 10.5 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMD61700.1 - 0.0008 19.5 0.1 0.78 9.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.16 EMD61700.1 - 0.0017 17.5 0.4 1 8.5 0.0 3.3 2 2 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMD61700.1 - 0.0054 16.6 0.0 1 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EMD61700.1 - 0.0079 16.0 4.1 0.75 9.5 0.0 3.6 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 EMD61700.1 - 0.0098 14.8 0.3 0.32 9.8 0.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EMD61700.1 - 0.018 15.0 6.8 1.4 8.8 0.0 4.3 3 2 1 5 5 4 0 AAA domain PduV-EutP PF10662.4 EMD61700.1 - 0.019 14.4 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EMD61700.1 - 0.027 14.0 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMD61700.1 - 0.037 13.1 0.0 6 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMD61700.1 - 0.046 14.0 2.9 16 5.8 0.0 3.3 3 0 0 3 3 3 0 ABC transporter UPF0079 PF02367.12 EMD61700.1 - 0.054 13.1 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EMD61700.1 - 0.054 13.0 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EMD61700.1 - 0.061 13.8 2.6 0.27 11.7 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein OEP PF02321.13 EMD61700.1 - 0.11 12.0 16.6 0.22 11.0 11.5 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein AAA_15 PF13175.1 EMD61700.1 - 0.14 11.1 2.1 0.25 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain GAS PF13851.1 EMD61700.1 - 0.15 11.2 15.6 0.12 11.4 9.4 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Zeta_toxin PF06414.7 EMD61700.1 - 0.19 10.8 5.0 0.43 9.6 0.0 3.1 3 1 0 3 3 3 0 Zeta toxin GBP_C PF02841.9 EMD61700.1 - 0.44 9.7 12.4 0.72 8.9 8.6 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF87 PF01935.12 EMD61700.1 - 1.1 9.0 6.9 23 4.7 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function DUF87 DivIC PF04977.10 EMD61700.1 - 1.6 8.2 17.5 0.91 9.0 6.2 2.5 1 1 1 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 EMD61700.1 - 1.9 8.0 13.5 3.9 7.1 9.4 1.4 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 EMD61700.1 - 2.2 6.0 8.9 3.2 5.4 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PTPlike_phytase PF14566.1 EMD61700.1 - 7 6.6 7.6 12 5.9 4.3 2.0 1 1 1 2 2 2 0 Inositol hexakisphosphate EF1_GNE PF00736.14 EMD61701.1 - 2.5e-31 107.2 4.3 4.5e-31 106.4 3.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMD61701.1 - 1.5e-14 53.8 9.3 4.6e-14 52.2 6.4 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EMD61701.1 - 0.00056 20.3 0.0 0.0022 18.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3902 PF13042.1 EMD61702.1 - 0.24 10.6 9.1 0.99 8.6 6.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3902) DUF202 PF02656.10 EMD61702.1 - 8.4 6.6 16.1 15 5.9 2.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PNP_UDP_1 PF01048.15 EMD61703.1 - 5.3e-19 68.1 1.1 1.3e-17 63.6 0.7 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily Hira PF07569.6 EMD61704.1 - 1.4e-79 266.3 0.0 2.6e-79 265.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EMD61704.1 - 3.3e-40 134.5 18.8 9.2e-08 31.6 0.0 8.7 7 1 1 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EMD61704.1 - 1.8e-11 43.2 0.7 5.1e-11 41.8 0.5 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EMD61704.1 - 0.0011 18.5 0.2 10 5.8 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EMD61704.1 - 0.0088 13.9 0.0 0.14 9.9 0.0 2.2 2 0 0 2 2 2 1 IKI3 family Mucin PF01456.12 EMD61704.1 - 0.03 14.0 13.0 0.079 12.7 9.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein YmzC PF14157.1 EMD61704.1 - 0.031 14.1 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 YmzC-like protein MMS1_N PF10433.4 EMD61704.1 - 0.032 12.3 0.0 0.08 11.0 0.0 1.6 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2360 PF10152.4 EMD61704.1 - 0.91 9.7 5.0 0.63 10.3 0.4 2.7 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Dicty_REP PF05086.7 EMD61704.1 - 6.8 4.3 4.6 11 3.6 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-U1 PF06220.7 EMD61705.1 - 1.4e-08 34.1 0.2 2.1e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger MFS_1 PF07690.11 EMD61706.1 - 1.7e-47 161.8 35.0 1.7e-47 161.8 24.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD61706.1 - 1.6e-09 36.8 27.2 3.7e-09 35.6 18.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EMD61706.1 - 3e-05 22.2 9.6 0.00023 19.3 5.2 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family HLH PF00010.21 EMD61707.1 - 2e-14 53.0 0.4 3.7e-14 52.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.4 EMD61707.1 - 0.13 10.8 6.6 0.19 10.3 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LIN37 PF15306.1 EMD61707.1 - 1.9 8.4 10.9 7.7 6.4 0.5 2.7 2 0 0 2 2 2 0 LIN37 Podoplanin PF05808.6 EMD61710.1 - 0.094 12.2 0.2 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Podoplanin UXS1_N PF11803.3 EMD61710.1 - 0.12 12.1 0.2 0.43 10.3 0.0 1.9 1 1 1 2 2 2 0 UDP-glucuronate decarboxylase N-terminal IBN_N PF03810.14 EMD61712.1 - 1.7e-09 37.4 0.2 3.4e-07 30.0 0.1 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMD61712.1 - 6.7e-06 26.0 0.2 0.001 19.0 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein HORMA PF02301.13 EMD61713.1 - 4.8e-22 78.4 0.0 6.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Acetyltransf_9 PF13527.1 EMD61714.1 - 0.0004 20.2 0.1 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD61714.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IBR PF01485.16 EMD61715.1 - 3.4e-05 23.6 7.1 3.4e-05 23.6 5.0 3.7 4 1 0 4 4 4 2 IBR domain Thr_synth_N PF14821.1 EMD61716.1 - 5e-30 103.3 0.0 1.2e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EMD61716.1 - 8.5e-20 71.1 0.0 3.6e-19 69.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pox_VLTF3 PF04947.9 EMD61716.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like NAD_binding_2 PF03446.10 EMD61717.1 - 4.3e-26 91.7 0.0 6.2e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD61717.1 - 3.4e-07 30.3 0.0 5.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMD61717.1 - 1.3e-05 25.5 0.0 4.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Leo1 PF04004.8 EMD61718.1 - 4.9e-33 114.2 0.2 9.8e-33 113.2 0.2 1.5 1 0 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.12 EMD61719.1 - 1.3e-35 122.6 0.3 1.9e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Arf PF00025.16 EMD61720.1 - 6.4e-80 266.4 0.2 7.3e-80 266.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD61720.1 - 2.9e-14 52.6 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMD61720.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMD61720.1 - 9.2e-13 47.6 1.6 1.1e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMD61720.1 - 4.8e-11 42.2 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD61720.1 - 2.3e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD61720.1 - 3.7e-06 26.8 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD61720.1 - 0.007 15.8 0.1 0.063 12.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EMD61720.1 - 0.0085 15.1 0.3 0.015 14.3 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EMD61720.1 - 0.043 13.6 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain MAPEG PF01124.13 EMD61721.1 - 0.047 13.3 12.9 0.18 11.4 8.9 1.9 1 1 0 1 1 1 0 MAPEG family p450 PF00067.17 EMD61722.1 - 3e-61 207.3 0.0 3.9e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 EMD61723.1 - 5.6e-46 156.7 0.0 1e-45 155.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMD61723.1 - 6.6e-27 93.6 0.0 1.6e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 EMD61724.1 - 1.4e-183 610.1 0.1 1.6e-183 609.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AdoHcyase PF05221.12 EMD61725.1 - 6.2e-137 454.8 0.1 7.2e-137 454.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMD61725.1 - 5.4e-84 279.9 1.8 8.3e-84 279.3 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMD61725.1 - 1.1e-07 31.2 0.6 1.8e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EMD61725.1 - 0.00026 20.6 0.1 0.00046 19.8 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EMD61725.1 - 0.0021 17.4 0.3 0.0036 16.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMD61725.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.1 EMD61725.1 - 0.0083 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 3HCDH_N PF02737.13 EMD61725.1 - 0.06 12.9 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HET PF06985.6 EMD61726.1 - 1.1e-40 138.9 1.6 1.6e-40 138.4 1.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 EMD61727.1 - 1.1e-31 107.0 1.0 3e-08 33.0 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMD61727.1 - 1.9e-29 101.8 0.6 1.5e-13 50.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD61727.1 - 2.5e-29 101.1 2.9 3.8e-11 43.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD61727.1 - 5.7e-23 80.4 10.7 7.1e-09 35.6 0.3 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD61727.1 - 5.9e-19 66.2 0.7 0.00082 19.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat SchA_CurD PF04486.7 EMD61727.1 - 0.076 12.8 0.1 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 SchA/CurD like domain ABC_tran PF00005.22 EMD61728.1 - 3.5e-46 156.8 0.6 1.4e-21 77.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EMD61728.1 - 5.7e-21 74.1 5.5 5.7e-21 74.1 3.8 3.6 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.1 EMD61728.1 - 4.7e-17 62.8 0.4 0.00029 20.9 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EMD61728.1 - 7e-10 38.5 0.5 0.019 14.2 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMD61728.1 - 3e-08 34.4 0.1 0.0079 17.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD61728.1 - 4.4e-06 26.8 0.1 0.15 12.2 0.0 3.0 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 EMD61728.1 - 6.7e-06 26.6 0.0 0.0063 17.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EMD61728.1 - 8.9e-06 25.0 0.1 0.3 10.0 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_16 PF13191.1 EMD61728.1 - 1.6e-05 24.9 1.8 0.0015 18.5 0.2 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.1 EMD61728.1 - 2.3e-05 23.8 0.1 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMD61728.1 - 3.4e-05 23.0 0.0 0.086 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMD61728.1 - 3.5e-05 24.1 0.0 0.29 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EMD61728.1 - 0.00019 21.8 12.5 0.046 14.0 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 EMD61728.1 - 0.00019 21.3 0.1 0.71 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMD61728.1 - 0.0003 20.7 0.0 0.068 13.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EMD61728.1 - 0.00034 20.3 0.1 0.47 10.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EMD61728.1 - 0.0005 20.0 2.0 0.062 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD61728.1 - 0.00065 19.3 0.2 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EMD61728.1 - 0.0013 18.9 0.1 2.7 8.1 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMD61728.1 - 0.002 17.5 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMD61728.1 - 0.002 17.6 0.1 2.7 7.3 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 EMD61728.1 - 0.0062 15.6 0.1 0.37 9.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EMD61728.1 - 0.0067 16.3 0.0 5.1 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMD61728.1 - 0.0098 16.0 0.0 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 EMD61728.1 - 0.01 14.6 0.3 3.5 6.3 0.0 2.6 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EMD61728.1 - 0.012 15.4 0.2 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 Dynamin family SbcCD_C PF13558.1 EMD61728.1 - 0.012 15.5 0.5 5.5 6.9 0.1 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EMD61728.1 - 0.025 14.3 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EMD61728.1 - 0.078 12.4 0.5 9.3 5.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EMD61728.1 - 0.08 12.6 0.2 8.4 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EMD61728.1 - 0.098 12.0 0.6 6.8 6.0 0.1 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EMD61728.1 - 0.14 11.7 0.2 16 5.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Nicastrin PF05450.10 EMD61729.1 - 0.0085 15.3 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Nicastrin HNOBA PF07701.9 EMD61729.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated SGL PF08450.7 EMD61731.1 - 0.00022 20.6 0.1 0.0053 16.1 0.0 2.5 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region GSDH PF07995.6 EMD61731.1 - 0.0018 17.4 0.9 0.81 8.7 0.7 3.3 3 1 0 3 3 3 2 Glucose / Sorbosone dehydrogenase alpha-hel2 PF14456.1 EMD61733.1 - 0.14 10.9 0.9 0.25 10.0 0.6 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Ribosomal_L23 PF00276.15 EMD61735.1 - 3.4e-13 49.3 0.0 6.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 PBP_sp32 PF07222.7 EMD61735.1 - 0.0015 17.7 0.8 0.0022 17.2 0.5 1.1 1 0 0 1 1 1 1 Proacrosin binding protein sp32 Fungal_trans PF04082.13 EMD61737.1 - 9.7e-11 41.0 0.4 2.8e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.14 EMD61738.1 - 6.1e-47 159.0 0.0 8.9e-47 158.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD61738.1 - 1.5e-17 63.3 0.0 2.4e-17 62.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD61738.1 - 8.7e-05 22.4 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EMD61738.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans PF04082.13 EMD61739.1 - 5.1e-13 48.4 0.4 8.2e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PsbN PF02468.10 EMD61739.1 - 0.045 13.3 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) HpcH_HpaI PF03328.9 EMD61740.1 - 5.6e-33 113.6 0.0 8.4e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3357 PF11837.3 EMD61740.1 - 0.0068 16.2 0.4 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) PEP-utilizers_C PF02896.13 EMD61740.1 - 0.016 14.1 0.2 0.19 10.5 0.2 2.5 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.11 EMD61741.1 - 1e-30 106.6 27.3 1e-30 106.6 18.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 EMD61741.1 - 0.001 17.8 3.0 0.002 16.8 2.1 1.4 1 0 0 1 1 1 1 PUCC protein DUF4231 PF14015.1 EMD61741.1 - 0.22 11.5 4.0 2.8 7.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Prefoldin PF02996.12 EMD61743.1 - 1.2e-23 83.0 0.0 1.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EMD61743.1 - 0.012 15.3 0.6 4.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Mating_N PF12731.2 EMD61743.1 - 0.051 13.4 0.7 0.089 12.6 0.5 1.3 1 0 0 1 1 1 0 Mating-type protein beta 1 Baculo_PEP_C PF04513.7 EMD61743.1 - 0.062 13.1 0.2 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRC_subunit PF08624.5 EMD61746.1 - 1.1e-54 184.0 0.0 1.5e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit zf-met PF12874.2 EMD61748.1 - 1.6e-05 24.9 1.9 3.7e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EMD61748.1 - 0.045 13.0 0.9 0.093 12.0 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.20 EMD61749.1 - 9.8e-20 70.0 0.0 1.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EMD61749.1 - 2e-12 46.4 10.1 8.3e-06 25.3 1.3 4.9 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD61749.1 - 3.8e-07 29.7 5.4 0.001 18.7 1.8 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMD61749.1 - 0.00066 19.3 4.1 33 5.0 0.0 5.7 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EMD61749.1 - 0.067 13.4 4.6 80 4.1 0.0 5.8 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EMD61749.1 - 0.12 12.4 9.0 1.7e+02 2.7 0.0 6.3 7 1 0 7 7 7 0 Leucine Rich repeat Cupin_8 PF13621.1 EMD61750.1 - 5.1e-30 104.7 0.0 7.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EMD61750.1 - 7.5e-08 32.6 0.0 2.9e-07 30.7 0.0 2.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EMD61750.1 - 0.00066 19.0 0.0 0.0015 17.8 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 EMD61750.1 - 0.001 18.5 0.0 0.0058 16.0 0.0 2.1 2 0 0 2 2 2 1 Cupin domain V-ATPase_H_N PF03224.9 EMD61751.1 - 6.6e-79 265.2 0.2 1.1e-78 264.5 0.1 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EMD61751.1 - 2.7e-39 133.7 0.2 8e-39 132.2 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H RNB PF00773.14 EMD61752.1 - 1.6e-95 320.1 1.0 2.5e-95 319.4 0.7 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EMD61752.1 - 1.4e-08 34.9 0.6 2.2e-07 31.0 0.1 2.8 2 0 0 2 2 2 1 PIN domain RCR PF12273.3 EMD61753.1 - 0.006 17.1 0.2 0.011 16.2 0.1 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF347 PF03988.7 EMD61753.1 - 0.099 12.5 1.1 0.15 11.9 0.8 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Apq12 PF12716.2 EMD61754.1 - 2.9e-20 71.6 9.6 5e-20 70.9 6.7 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis TraD_N PF12615.3 EMD61754.1 - 0.0035 17.6 0.1 0.048 14.0 0.0 2.2 2 0 0 2 2 2 1 F sex factor protein N terminal vMSA PF00695.14 EMD61754.1 - 0.12 11.5 0.7 0.15 11.1 0.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ESCRT-II PF05871.7 EMD61756.1 - 1.6e-49 167.4 0.0 1.9e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PPR_1 PF12854.2 EMD61756.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PPR repeat PPR PF01535.15 EMD61756.1 - 0.14 12.1 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat SH3_9 PF14604.1 EMD61757.1 - 1.9e-06 27.3 0.1 3.4e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMD61757.1 - 0.00065 19.0 0.4 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 SH3 domain DUF2668 PF10873.3 EMD61757.1 - 0.0089 16.2 0.1 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Podoplanin PF05808.6 EMD61757.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DAP10 PF07213.6 EMD61757.1 - 0.025 14.3 5.2 0.16 11.7 0.2 2.6 2 0 0 2 2 2 0 DAP10 membrane protein Mid2 PF04478.7 EMD61757.1 - 0.17 11.3 1.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 EMD61757.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EMD61757.1 - 0.36 10.3 1.2 0.62 9.6 0.8 1.3 1 0 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 EMD61758.1 - 7.7e-09 35.4 14.9 5.1e-06 26.5 0.6 7.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMD61758.1 - 0.00073 19.7 68.2 0.011 16.0 0.6 8.6 9 1 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD61758.1 - 0.004 17.3 0.9 0.004 17.3 0.6 9.5 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD61758.1 - 2.3 8.4 22.3 0.19 11.8 0.6 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD61758.1 - 3 8.1 16.8 8.5 6.7 0.3 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ASFV_J13L PF05568.6 EMD61759.1 - 2.8 7.4 7.1 3.3 7.1 4.9 1.0 1 0 0 1 1 1 0 African swine fever virus J13L protein PPR_2 PF13041.1 EMD61760.1 - 4.5e-48 161.0 4.8 2e-09 37.2 0.0 13.8 10 3 5 15 15 15 12 PPR repeat family PPR PF01535.15 EMD61760.1 - 4.2e-24 82.7 15.5 0.00023 20.9 0.0 13.3 17 0 0 17 17 17 5 PPR repeat PPR_1 PF12854.2 EMD61760.1 - 1.4e-22 78.8 2.1 6.5e-08 31.9 0.0 10.7 12 0 0 12 12 12 4 PPR repeat PPR_3 PF13812.1 EMD61760.1 - 5.8e-22 76.0 37.9 0.0001 22.2 0.0 16.6 19 1 1 20 20 20 6 Pentatricopeptide repeat domain RPM2 PF08579.6 EMD61760.1 - 1.5e-05 25.1 0.1 0.0009 19.3 0.0 3.2 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EMD61760.1 - 0.01 14.7 0.1 5 5.9 0.0 4.2 5 0 0 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway GHMP_kinases_N PF00288.21 EMD61761.1 - 5.4e-13 48.8 0.2 3.4e-12 46.2 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMD61761.1 - 6.8e-08 32.6 0.0 1.6e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal DUF4510 PF14971.1 EMD61761.1 - 0.044 13.9 0.1 0.089 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Ribosomal_L29 PF00831.18 EMD61762.1 - 5.5e-18 64.4 0.3 5.5e-18 64.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.3 EMD61763.1 - 1.5e-14 53.8 0.2 1.5e-14 53.8 0.1 3.7 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus BMP2K_C PF15282.1 EMD61763.1 - 0.056 13.6 0.2 0.074 13.2 0.1 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus AAA_13 PF13166.1 EMD61763.1 - 0.1 11.0 3.1 0.12 10.7 2.1 1.0 1 0 0 1 1 1 0 AAA domain STAT_alpha PF01017.15 EMD61763.1 - 0.3 10.7 5.6 4.5 6.9 0.6 2.7 1 1 0 2 2 2 0 STAT protein, all-alpha domain DUF4570 PF15134.1 EMD61763.1 - 0.6 9.9 7.7 0.97 9.3 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) Not3 PF04065.10 EMD61763.1 - 0.92 8.7 4.7 0.53 9.5 1.6 1.6 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component FliT PF05400.8 EMD61763.1 - 0.96 9.8 16.0 0.65 10.4 5.2 3.0 2 1 1 3 3 3 0 Flagellar protein FliT IncA PF04156.9 EMD61763.1 - 2.6 7.6 11.7 3.3 7.2 7.7 1.5 1 1 0 1 1 1 0 IncA protein FliJ PF02050.11 EMD61763.1 - 8.4 6.4 11.1 0.26 11.3 1.5 2.6 2 1 1 3 3 3 0 Flagellar FliJ protein ATP-synt_10 PF05176.9 EMD61764.1 - 1.4e-71 240.7 0.0 1.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Apc15p PF05841.6 EMD61764.1 - 0.054 14.2 0.0 0.09 13.5 0.0 1.4 1 0 0 1 1 1 0 Apc15p protein COesterase PF00135.23 EMD61765.1 - 9.1e-96 321.6 0.0 1.2e-95 321.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD61765.1 - 7e-10 38.8 0.0 2.2e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD61765.1 - 0.00047 19.4 0.1 0.00079 18.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD61765.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DNA_pol_B_palm PF14792.1 EMD61766.1 - 4.5e-31 107.2 0.0 1.2e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EMD61766.1 - 5.4e-22 77.2 0.0 1.1e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EMD61766.1 - 7.9e-19 66.9 0.0 6.9e-18 63.9 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EMD61766.1 - 3.7e-17 62.2 0.9 1.2e-16 60.6 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EMD61766.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain MFS_1 PF07690.11 EMD61767.1 - 3.5e-24 85.1 33.0 3.5e-24 85.1 22.9 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3554 PF12074.3 EMD61767.1 - 0.055 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) DUF1191 PF06697.7 EMD61767.1 - 0.4 9.4 5.2 0.4 9.4 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1191) DDE_1 PF03184.14 EMD61768.1 - 1.5e-15 56.8 0.0 1.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Nodulin_late PF07127.6 EMD61770.1 - 0.13 12.4 2.5 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Late nodulin protein DDE_3 PF13358.1 EMD61772.1 - 2.1e-33 115.1 0.0 3.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EMD61772.1 - 5.6e-09 36.1 0.0 4.2e-08 33.3 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain DDE_1 PF03184.14 EMD61772.1 - 7.4e-09 35.0 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EMD61772.1 - 6.3e-05 22.4 0.3 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EMD61772.1 - 0.00022 21.9 0.1 0.00066 20.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 EMD61772.1 - 0.094 11.4 0.0 0.29 9.8 0.0 1.7 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Prominin PF05478.6 EMD61774.1 - 0.065 10.7 0.1 0.11 10.0 0.0 1.3 1 1 0 1 1 1 0 Prominin Aldo_ket_red PF00248.16 EMD61775.1 - 1.8e-63 213.9 0.1 2.1e-63 213.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_2 PF00891.13 EMD61776.1 - 2.3e-30 105.5 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EMD61776.1 - 0.055 12.8 0.1 3.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain VanW PF04294.8 EMD61776.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 VanW like protein Pyridoxal_deC PF00282.14 EMD61777.1 - 6.5e-78 261.7 0.0 3.6e-77 259.3 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMD61777.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLS PF14611.1 EMD61777.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Aminotran_5 PF00266.14 EMD61777.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.23 EMD61778.1 - 9.5e-251 831.3 1.1 6.8e-87 291.5 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EMD61778.1 - 1.1e-138 461.1 1.3 5.8e-58 196.1 0.1 3.5 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EMD61778.1 - 6.7e-44 148.0 1.0 1.9e-14 53.6 0.0 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD61778.1 - 3e-24 85.7 5.9 2.8e-06 28.1 0.0 5.4 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EMD61778.1 - 2.5e-23 82.1 1.3 5.3e-22 77.9 0.2 3.4 3 0 0 3 3 3 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 EMD61778.1 - 1.8e-05 24.5 0.0 0.0039 16.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD61778.1 - 3.2e-05 24.2 0.0 0.0001 22.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61778.1 - 0.0001 21.8 0.0 0.00031 20.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61778.1 - 0.001 19.5 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61778.1 - 0.001 19.6 0.0 0.0037 17.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DUF2806 PF10987.3 EMD61778.1 - 0.011 15.2 3.7 11 5.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2806) NAD_binding_4 PF07993.7 EMD61779.1 - 1.5e-35 122.3 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMD61779.1 - 7.8e-10 38.5 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD61779.1 - 0.0001 21.1 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.23 EMD61780.1 - 2e-193 642.4 2.7 1.4e-92 310.3 0.0 3.7 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 EMD61780.1 - 2.9e-102 341.5 0.0 3.7e-57 193.4 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EMD61780.1 - 2.3e-40 136.6 0.8 1.4e-13 50.9 0.0 3.6 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EMD61780.1 - 4.3e-25 87.8 0.7 2.7e-23 82.0 0.2 3.0 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EMD61780.1 - 1.7e-23 83.3 7.1 2.8e-06 28.1 0.0 5.4 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 EMD61780.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD61780.1 - 0.00042 20.0 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMD61780.1 - 0.00046 19.6 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMD61780.1 - 0.009 16.5 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD61780.1 - 0.076 13.5 0.0 0.34 11.4 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMD61780.1 - 0.09 11.7 0.0 0.23 10.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Csm1 PF12539.3 EMD61780.1 - 0.24 11.9 0.6 63 4.1 0.3 3.6 4 0 0 4 4 3 0 Chromosome segregation protein Csm1/Pcs1 FAD_binding_3 PF01494.14 EMD61781.1 - 1.3e-27 96.7 0.0 3.7e-27 95.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD61781.1 - 7.5e-05 22.6 0.9 0.00024 21.0 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD61781.1 - 0.00017 20.6 5.1 0.012 14.5 1.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EMD61781.1 - 0.0004 19.3 0.0 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 EMD61781.1 - 0.0026 16.9 0.6 0.0046 16.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMD61781.1 - 0.0032 17.8 4.4 0.085 13.2 0.8 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD61781.1 - 0.01 14.8 0.4 5.4 5.8 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMD61781.1 - 0.014 15.2 2.4 0.14 11.9 1.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD61781.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD61781.1 - 0.17 10.6 1.2 0.26 10.0 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.21 EMD61782.1 - 1.2e-10 40.9 0.0 4.2e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EMD61782.1 - 0.00084 19.0 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMD61782.1 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMD61782.1 - 0.0028 17.4 0.0 0.13 12.0 0.0 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD61782.1 - 0.0038 16.6 0.1 0.0064 15.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_N PF08240.7 EMD61782.1 - 0.026 14.2 0.4 0.57 9.9 0.0 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 EMD61782.1 - 0.057 12.4 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EMD61782.1 - 0.083 12.9 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EMD61782.1 - 0.099 13.0 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF43 PF01861.11 EMD61782.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 AlaDh_PNT_C PF01262.16 EMD61782.1 - 0.13 11.8 0.1 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain A2M_comp PF07678.9 EMD61783.1 - 0.018 14.2 0.1 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 A-macroglobulin complement component zf-RNPHF PF08080.7 EMD61783.1 - 0.3 10.6 1.1 0.55 9.7 0.1 1.9 2 0 0 2 2 2 0 RNPHF zinc finger DUF3425 PF11905.3 EMD61784.1 - 4.1e-12 46.1 0.2 8.7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMD61784.1 - 0.0032 17.3 8.8 0.013 15.3 6.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD61784.1 - 0.21 11.4 4.3 0.35 10.7 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper E1-E2_ATPase PF00122.15 EMD61785.1 - 2.5e-32 111.7 0.1 6.9e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD61785.1 - 2.6e-26 93.3 0.3 4.1e-26 92.7 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD61785.1 - 5.4e-13 49.5 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMD61785.1 - 7.7e-07 29.1 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF59 PF01883.14 EMD61785.1 - 0.077 12.9 0.3 0.36 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF59 ketoacyl-synt PF00109.21 EMD61786.1 - 3.4e-52 177.4 0.0 1.1e-51 175.7 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMD61786.1 - 6.5e-34 116.3 1.9 1.6e-33 115.0 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMD61786.1 - 1.3e-05 24.2 0.1 3.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EMD61786.1 - 0.016 14.8 0.4 0.071 12.7 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NifW PF03206.9 EMD61786.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW zf-3CxxC PF13695.1 EMD61788.1 - 2.5e-23 82.1 5.3 2.5e-23 82.1 3.7 2.5 2 1 0 2 2 2 1 Zinc-binding domain zf-C2H2_jaz PF12171.3 EMD61788.1 - 3.4e-08 33.3 4.2 3.2e-05 23.9 0.1 3.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD61788.1 - 0.00018 21.6 7.6 0.0072 16.4 0.4 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD61788.1 - 0.0051 16.6 17.7 0.02 14.7 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger PsbQ PF05757.6 EMD61788.1 - 0.079 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Pribosyltran PF00156.22 EMD61789.1 - 1.1e-15 57.4 0.0 2.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 EMD61789.1 - 4.9e-13 48.7 3.7 6e-13 48.4 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 EMD61789.1 - 2.7e-08 33.5 0.0 5.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase Methyltransf_23 PF13489.1 EMD61789.1 - 0.00054 19.7 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPRTase PF14681.1 EMD61789.1 - 0.0019 17.4 0.0 0.0042 16.3 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.7 EMD61789.1 - 0.051 13.4 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like PRTase_2 PF15609.1 EMD61789.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF3238 PF11579.3 EMD61789.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) zf-C2H2_jaz PF12171.3 EMD61791.1 - 4.9e-23 80.6 34.7 6.1e-05 23.0 0.3 6.6 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD61791.1 - 1.7e-19 69.2 40.3 0.0013 18.8 0.4 7.6 6 1 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMD61791.1 - 2e-12 47.1 41.1 0.027 14.5 0.1 7.0 2 2 5 7 7 7 6 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMD61791.1 - 6.5e-11 41.7 38.6 0.0075 16.5 2.2 7.5 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD61791.1 - 3.8e-09 36.3 49.3 0.083 13.2 0.5 7.5 6 1 1 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD61791.1 - 1.7e-05 24.5 44.4 0.26 11.2 0.3 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD61791.1 - 0.00051 20.2 39.1 0.27 11.5 0.1 7.4 7 0 0 7 7 7 3 Zinc-finger double domain PI3K_p85B PF02192.11 EMD61791.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain ABM PF03992.11 EMD61791.1 - 0.022 14.7 0.1 0.63 10.1 0.0 2.8 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Rad50_zn_hook PF04423.9 EMD61791.1 - 0.18 11.2 7.2 2.5 7.6 0.0 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Dynamin_N PF00350.18 EMD61792.1 - 6.5e-07 29.3 1.3 0.0017 18.2 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 EMD61792.1 - 0.026 15.0 0.1 0.57 10.7 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein MobB PF03205.9 EMD61792.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B adh_short PF00106.20 EMD61793.1 - 2e-12 47.3 2.9 3.5e-12 46.5 2.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD61793.1 - 2.4e-05 24.1 2.4 0.00054 19.6 1.7 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD61793.1 - 0.078 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.19 EMD61794.1 - 9.4e-97 324.4 23.5 1.1e-96 324.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61794.1 - 6.6e-23 80.9 20.4 6.6e-23 80.9 14.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMD61794.1 - 0.00024 19.6 1.3 0.00024 19.6 0.9 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Velvet PF11754.3 EMD61795.1 - 3e-38 131.4 0.0 3.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Velvet factor zf-C3HC4_3 PF13920.1 EMD61796.1 - 0.00015 21.3 10.3 0.00015 21.3 7.1 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 EMD61796.1 - 0.09 12.5 1.2 0.17 11.5 0.3 1.8 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Mnd1 PF03962.10 EMD61797.1 - 1.5e-46 158.4 2.0 1.9e-46 158.1 1.4 1.0 1 0 0 1 1 1 1 Mnd1 family DUF4315 PF14193.1 EMD61797.1 - 0.0079 16.0 0.8 0.0079 16.0 0.6 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4315) TBPIP PF07106.8 EMD61797.1 - 0.017 14.6 4.8 0.029 13.9 3.3 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EMD61797.1 - 0.041 13.4 6.7 0.059 12.9 4.6 1.4 1 1 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EMD61797.1 - 0.21 10.5 3.2 0.24 10.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EMD61797.1 - 0.27 9.6 3.6 0.3 9.4 2.5 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 EMD61797.1 - 0.49 10.2 8.7 0.83 9.5 6.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RNA_pol_Rpc82 PF05645.8 EMD61797.1 - 0.79 9.2 3.7 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 CENP-F_leu_zip PF10473.4 EMD61797.1 - 1.2 8.9 11.9 3.7 7.4 8.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EMD61797.1 - 1.9 7.4 7.3 2.7 6.9 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EMD61797.1 - 2.3 8.2 8.3 82 3.2 5.7 2.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EMD61797.1 - 4.1 7.1 12.4 9.4 5.9 1.2 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein WD40 PF00400.27 EMD61799.1 - 8.5e-28 95.2 12.5 2.9e-08 33.2 0.5 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat TSNR_N PF04705.7 EMD61799.1 - 0.18 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus CENP-I PF07778.6 EMD61800.1 - 0.15 10.2 0.1 0.28 9.3 0.1 1.4 1 0 0 1 1 1 0 Mis6 Methyltransf_16 PF10294.4 EMD61801.1 - 2.8e-44 150.6 0.0 3.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EMD61801.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61801.1 - 0.0028 18.1 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD61801.1 - 0.0084 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMD61801.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMD61801.1 - 0.041 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMD61801.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SIT PF15330.1 EMD61802.1 - 0.0037 17.3 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4117 PF13491.1 EMD61802.1 - 0.031 13.7 2.1 0.042 13.2 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) DAP10 PF07213.6 EMD61802.1 - 0.072 12.8 0.9 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 DAP10 membrane protein MM_CoA_mutase PF01642.17 EMD61802.1 - 0.077 11.1 0.1 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Hce2 PF14856.1 EMD61803.1 - 0.0034 17.2 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TMC PF07810.8 EMD61804.1 - 0.37 11.2 3.9 0.39 11.1 0.6 2.3 2 0 0 2 2 2 0 TMC domain DEAD PF00270.24 EMD61805.1 - 2.6e-41 140.9 0.0 1.5e-40 138.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61805.1 - 5.5e-26 90.2 0.1 1.2e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EMD61805.1 - 0.0043 17.3 4.3 0.0043 17.3 3.0 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2986) CMS1 PF14617.1 EMD61805.1 - 0.27 10.2 0.0 0.27 10.2 0.0 2.4 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Hamartin PF04388.7 EMD61805.1 - 0.72 8.4 2.5 1.1 7.8 1.7 1.2 1 0 0 1 1 1 0 Hamartin protein Proteasome PF00227.21 EMD61806.1 - 3.2e-39 134.1 0.0 3.8e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 EMD61809.1 - 9.1e-46 155.5 0.0 3.2e-30 104.8 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EMD61809.1 - 8.5e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature His_Phos_1 PF00300.17 EMD61810.1 - 2.5e-20 73.1 0.0 3.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2215 PF10225.4 EMD61810.1 - 0.14 11.5 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) ADK PF00406.17 EMD61812.1 - 1.2e-44 151.8 0.0 1.6e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EMD61812.1 - 3.5e-08 33.8 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD61812.1 - 4.5e-06 27.4 0.0 7.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMD61812.1 - 0.0001 21.7 0.2 0.01 15.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EMD61812.1 - 0.00052 19.9 0.1 0.004 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EMD61812.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PCI PF01399.22 EMD61813.1 - 1.5e-12 47.7 0.0 5.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.1 EMD61813.1 - 0.071 13.7 1.6 0.33 11.6 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMD61817.1 - 7.6e-81 271.9 19.1 9.1e-81 271.7 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61817.1 - 7e-18 64.4 33.5 3.8e-10 39.0 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMD61817.1 - 0.034 12.6 17.3 0.0061 15.1 5.4 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Alpha-amylase PF00128.19 EMD61818.1 - 1.5e-99 333.3 1.2 2.4e-99 332.7 0.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EMD61818.1 - 0.00079 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 EMD61818.1 - 0.0098 14.8 0.1 0.024 13.5 0.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Zn_clus PF00172.13 EMD61819.1 - 1e-07 31.7 12.8 2e-07 30.7 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD61819.1 - 0.0015 17.4 0.3 0.0035 16.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain UPF0029 PF01205.14 EMD61821.1 - 5.8e-14 51.7 0.1 2.3e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RRM_3 PF08777.6 EMD61821.1 - 0.082 12.7 1.1 0.19 11.6 0.8 1.6 1 0 0 1 1 1 0 RNA binding motif Ribosomal_L34 PF00468.12 EMD61822.1 - 1.4e-17 63.1 7.2 1.4e-17 63.1 5.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L34 RNA_polI_A14 PF08203.6 EMD61823.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 Peptidase_M48 PF01435.13 EMD61824.1 - 5.7e-50 169.9 0.0 1.5e-49 168.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.6 EMD61824.1 - 0.00088 18.3 1.8 0.0047 15.9 0.8 2.3 2 1 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EMD61824.1 - 0.014 14.6 0.5 0.035 13.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF955 PF06114.8 EMD61824.1 - 0.03 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Peptidase_M57 PF12388.3 EMD61824.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Asp PF00026.18 EMD61825.1 - 5.1e-29 101.5 0.0 1.1e-28 100.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMD61825.1 - 2.7e-07 30.6 0.3 1.6e-06 28.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMD61825.1 - 0.13 12.7 0.0 3.2 8.3 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease TRAP_alpha PF03896.11 EMD61826.1 - 0.00074 18.5 0.1 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SKN1 PF03935.10 EMD61826.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) CDC45 PF02724.9 EMD61826.1 - 2.1 6.2 11.7 2.6 5.9 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.13 EMD61827.1 - 8e-17 60.9 3.0 8e-17 60.9 2.1 2.4 1 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61827.1 - 1.1e-08 34.7 9.8 1.8e-08 34.1 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 EMD61828.1 - 0.00026 20.4 1.8 0.00029 20.2 1.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2469 PF10611.4 EMD61828.1 - 0.062 13.6 0.2 0.092 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) CHIPS PF11434.3 EMD61828.1 - 0.32 10.6 3.5 0.35 10.5 2.5 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS HTH_psq PF05225.11 EMD61830.1 - 8.3e-08 31.6 0.2 1e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 EMD61830.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.7 EMD61830.1 - 0.067 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_Tc3_2 PF01498.13 EMD61830.1 - 0.081 13.0 0.2 0.088 12.8 0.1 1.1 1 0 0 1 1 1 0 Transposase RRS1 PF04939.7 EMD61831.1 - 5.1e-59 198.4 5.6 6.2e-59 198.1 3.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_L37 PF08561.5 EMD61831.1 - 6.8 6.3 9.9 0.83 9.2 3.1 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 DAP3 PF10236.4 EMD61832.1 - 1.7e-98 329.3 0.0 2.3e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EMD61832.1 - 0.037 13.9 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NOSIC PF08060.8 EMD61832.1 - 0.041 13.6 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 NOSIC (NUC001) domain Autophagy_act_C PF03987.10 EMD61833.1 - 5.4e-13 48.9 0.9 8.6e-13 48.2 0.6 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Pkinase PF00069.20 EMD61834.1 - 4.6e-75 252.1 0.0 6.3e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61834.1 - 9e-36 123.2 0.0 1.3e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMD61834.1 - 2.5e-16 59.5 0.1 7.1e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EMD61834.1 - 2.4e-11 43.1 0.0 1.7e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMD61834.1 - 0.0039 16.0 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EMD61834.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMD61834.1 - 0.054 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EMD61834.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EMD61834.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ThiS PF02597.15 EMD61834.1 - 0.086 13.2 0.1 0.43 11.0 0.1 2.2 1 1 0 1 1 1 0 ThiS family p450 PF00067.17 EMD61835.1 - 1.3e-76 258.0 0.0 1.6e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EMD61835.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 K-box region Pam17 PF08566.5 EMD61836.1 - 3e-59 199.5 0.0 4.2e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 AA_permease PF00324.16 EMD61838.1 - 1.7e-134 448.7 43.9 2.1e-134 448.4 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD61838.1 - 9.8e-35 119.8 46.7 1.2e-34 119.6 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease BLOC1_2 PF10046.4 EMD61842.1 - 0.0075 16.3 0.2 0.072 13.2 0.0 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 LysM PF01476.15 EMD61843.1 - 2e-09 37.1 0.1 3.6e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 LysM domain Toxin_32 PF08120.6 EMD61843.1 - 0.78 9.3 3.5 0.4 10.3 0.5 1.9 2 0 0 2 2 2 0 Tamulustoxin family Methyltransf_11 PF08241.7 EMD61844.1 - 2.3e-08 34.4 0.0 5.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD61844.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61844.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EMD61844.1 - 0.055 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Xan_ur_permease PF00860.15 EMD61845.1 - 1.5e-21 76.3 31.3 3.5e-21 75.1 18.6 2.5 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 EMD61845.1 - 0.007 15.4 4.5 0.007 15.4 3.1 2.5 2 1 1 3 3 3 1 Sulfate transporter family F-box PF00646.28 EMD61847.1 - 1.9e-07 30.5 0.9 3.7e-07 29.6 0.6 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD61847.1 - 0.00026 20.6 0.7 0.00068 19.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like Sugar_tr PF00083.19 EMD61852.1 - 9.4e-83 278.2 26.9 1.2e-82 277.9 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61852.1 - 7.6e-37 126.8 45.5 1.3e-31 109.6 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD61852.1 - 0.0013 17.0 3.5 0.0013 17.0 2.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMD61852.1 - 0.0067 16.1 0.5 5.9 6.7 0.1 2.9 2 0 0 2 2 2 2 MFS_1 like family Glyco_hydro_2_C PF02836.12 EMD61853.1 - 4.5e-98 327.8 0.2 6.9e-98 327.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EMD61853.1 - 5.1e-61 206.1 0.0 8.9e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EMD61853.1 - 2.3e-53 180.1 0.4 5e-53 179.0 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EMD61853.1 - 1.5e-13 51.1 0.1 4.7e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 FAD_binding_4 PF01565.18 EMD61855.1 - 6.9e-28 96.8 0.0 1e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EMD61855.1 - 5.7e-15 55.3 0.0 7.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sec_GG PF07549.9 EMD61856.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-H2C2_2 PF13465.1 EMD61858.1 - 2.9e-15 55.6 20.9 2.5e-07 30.6 2.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMD61858.1 - 5.6e-09 35.8 30.4 0.002 18.3 2.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD61858.1 - 1.3e-06 28.3 23.1 0.016 15.4 4.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMD61858.1 - 0.0029 17.6 6.1 0.0078 16.3 4.2 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding FlxA PF14282.1 EMD61858.1 - 0.0037 17.1 0.5 0.0037 17.1 0.3 2.2 2 0 0 2 2 2 1 FlxA-like protein zf-C2H2_jaz PF12171.3 EMD61858.1 - 0.0058 16.7 10.2 0.61 10.3 1.9 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EMD61858.1 - 0.009 15.5 7.9 0.013 15.0 0.9 2.7 1 1 1 2 2 2 1 GAGA factor Mito_fiss_reg PF05308.6 EMD61858.1 - 0.04 13.2 0.3 0.04 13.2 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial fission regulator zf-CHCC PF10276.4 EMD61858.1 - 0.1 12.4 7.3 0.75 9.6 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger domain Zn-ribbon_8 PF09723.5 EMD61858.1 - 0.21 11.5 7.8 2.1 8.3 2.2 3.1 1 1 1 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 EMD61858.1 - 0.21 11.5 8.3 0.21 11.5 1.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger Tmemb_cc2 PF10267.4 EMD61858.1 - 0.56 8.7 8.1 0.14 10.7 0.4 2.8 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein DZR PF12773.2 EMD61858.1 - 1.3 8.8 6.9 24 4.8 4.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EMD61858.1 - 2 8.5 5.9 21 5.1 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C1_4 PF07975.7 EMD61858.1 - 8.6 6.4 8.4 1.3e+02 2.7 0.2 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain Pkinase PF00069.20 EMD61860.1 - 3.5e-66 223.0 0.0 5e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61860.1 - 9.8e-49 165.7 0.0 1.5e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD61860.1 - 0.015 14.3 0.0 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like PI3_PI4_kinase PF00454.22 EMD61861.1 - 1.5e-36 126.0 0.0 9.1e-36 123.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMD61861.1 - 7.2e-24 83.9 0.2 1.8e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MFS_1 PF07690.11 EMD61862.1 - 4.8e-30 104.4 55.4 6.4e-30 104.0 35.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD61862.1 - 6.8e-10 37.7 12.9 6.8e-10 37.7 8.9 2.4 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD61862.1 - 4.7e-08 32.0 7.8 4.7e-08 32.0 5.4 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter SBP_bac_6 PF13343.1 EMD61863.1 - 3.7e-13 49.3 0.8 5.6e-13 48.7 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EMD61863.1 - 1.1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EMD61863.1 - 7.4e-05 22.6 5.5 0.0014 18.4 3.8 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein XYPPX PF02162.12 EMD61863.1 - 9 5.9 10.2 19 4.9 7.1 1.5 1 0 0 1 1 1 0 XYPPX repeat (two copies) SDH_alpha PF03313.10 EMD61864.1 - 0.43 9.5 3.0 0.57 9.1 2.1 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain DUF4601 PF15373.1 EMD61866.1 - 0.016 14.0 0.2 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) p450 PF00067.17 EMD61869.1 - 4.6e-60 203.4 0.0 5.6e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.10 EMD61870.1 - 8.2e-18 63.9 1.2 9.5e-18 63.7 0.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD61870.1 - 5.6e-15 55.2 0.4 6.5e-15 55.0 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMD61870.1 - 0.067 13.6 0.1 0.076 13.4 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like BMFP PF04380.8 EMD61870.1 - 0.093 12.8 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Membrane fusogenic activity HSP20 PF00011.16 EMD61871.1 - 2.3e-23 82.0 3.2 5.6e-15 55.0 0.2 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Fungal_trans_2 PF11951.3 EMD61872.1 - 2.9e-60 203.9 0.1 4.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61872.1 - 4.6e-09 36.0 7.7 8.8e-09 35.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDI PF02234.14 EMD61873.1 - 0.028 14.1 2.3 0.073 12.8 1.6 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Phage_GPO PF05929.6 EMD61873.1 - 0.43 9.7 2.6 0.55 9.4 1.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.8 EMD61873.1 - 0.54 10.7 5.4 0.82 10.1 3.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2681 PF10883.3 EMD61873.1 - 5 7.4 7.4 8.8 6.6 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) RAMP4 PF06624.7 EMD61874.1 - 0.00013 21.4 0.1 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.15 EMD61875.1 - 3.3e-76 256.7 0.0 9.5e-76 255.1 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EMD61875.1 - 0.0031 17.4 0.1 18 5.7 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.2 EMD61875.1 - 0.042 13.6 0.3 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EMD61875.1 - 4.7 7.8 8.8 20 5.8 0.0 5.6 6 1 1 7 7 7 0 HEAT-like repeat TPR_11 PF13414.1 EMD61876.1 - 1.7e-07 30.7 1.9 0.0019 17.7 0.5 4.0 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 EMD61876.1 - 1.7e-06 28.1 2.8 0.0035 17.8 0.2 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61876.1 - 8.4e-05 22.8 0.1 0.022 15.1 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMD61876.1 - 0.0017 18.1 0.2 0.0038 17.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.12 EMD61876.1 - 0.0065 16.7 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_2 PF07719.12 EMD61876.1 - 0.0084 15.9 1.3 3 7.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61876.1 - 0.012 15.7 1.5 4.4 7.7 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61876.1 - 0.018 15.7 4.8 0.17 12.6 0.0 3.5 2 1 1 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 EMD61878.1 - 4.4e-05 23.1 0.0 0.00031 20.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD61878.1 - 0.00019 21.0 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain DUF221 PF02714.10 EMD61879.1 - 2.5e-89 299.3 16.8 2.5e-89 299.3 11.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD61879.1 - 2.4e-43 147.4 1.6 2.4e-43 147.4 1.1 2.8 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMD61879.1 - 5.2e-23 81.3 1.1 9.4e-23 80.5 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Arrestin_N PF00339.24 EMD61880.1 - 7.7e-16 58.2 0.1 5.2e-15 55.5 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMD61880.1 - 3.4e-10 40.1 0.0 4.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Viral_env_E26 PF11050.3 EMD61881.1 - 0.00074 18.7 0.7 0.00096 18.4 0.5 1.2 1 0 0 1 1 1 1 Virus envelope protein E26 CHASE3 PF05227.8 EMD61881.1 - 0.0096 15.6 7.4 0.014 15.1 5.1 1.3 1 0 0 1 1 1 1 CHASE3 domain FCH PF00611.18 EMD61881.1 - 0.074 13.2 1.2 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Bap31 PF05529.7 EMD61881.1 - 0.15 11.4 6.4 0.23 10.9 4.4 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 EMD61881.1 - 0.3 10.0 9.6 0.6 9.0 6.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) G-patch PF01585.18 EMD61882.1 - 9e-07 28.5 0.1 9.9e-06 25.2 0.1 2.4 1 1 0 1 1 1 1 G-patch domain CRT10 PF08728.5 EMD61882.1 - 0.56 8.1 11.8 0.73 7.7 8.2 1.1 1 0 0 1 1 1 0 CRT10 Asp-B-Hydro_N PF05279.6 EMD61882.1 - 4.6 7.0 28.9 0.23 11.2 16.3 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region GHMP_kinases_N PF00288.21 EMD61883.1 - 1.2e-18 66.8 0.1 2.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMD61883.1 - 1.8e-08 34.4 0.0 4.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EMD61883.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature eIF3_subunit PF08597.5 EMD61884.1 - 1.3e-59 201.7 28.4 1.6e-59 201.4 19.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CodY PF06018.9 EMD61884.1 - 0.058 12.6 0.3 0.18 11.1 0.2 1.9 1 1 0 1 1 1 0 CodY GAF-like domain PRP4 PF08799.6 EMD61884.1 - 0.28 10.4 2.9 0.75 9.1 2.0 1.8 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like HisG PF01634.13 EMD61885.1 - 7e-51 172.0 0.1 1.1e-50 171.4 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EMD61885.1 - 1e-26 92.6 0.1 2.2e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EMD61885.1 - 0.043 13.3 0.1 0.14 11.7 0.1 1.8 1 1 0 1 1 1 0 NMT1/THI5 like MutS_V PF00488.16 EMD61886.1 - 4.6e-77 258.5 0.3 7.1e-77 257.9 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD61886.1 - 2.3e-32 112.4 0.8 7.4e-32 110.7 0.6 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EMD61886.1 - 4.7e-10 39.6 0.1 1.4e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMD61886.1 - 2.9e-08 33.7 0.1 7.1e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV WD40 PF00400.27 EMD61887.1 - 3.3e-85 277.2 21.6 2.2e-12 46.3 0.1 8.7 9 1 0 9 9 9 8 WD domain, G-beta repeat Nup160 PF11715.3 EMD61887.1 - 1.5e-06 26.6 5.3 0.18 9.9 0.0 4.9 4 2 1 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 EMD61887.1 - 0.00013 21.8 0.1 0.00024 21.0 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.1 EMD61887.1 - 0.00085 18.5 0.1 11 4.9 0.0 4.1 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EMD61887.1 - 0.065 12.9 1.1 26 4.5 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EMD61887.1 - 0.095 12.4 0.5 31 4.2 0.0 3.7 3 2 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DUF4164 PF13747.1 EMD61887.1 - 0.16 12.1 0.2 0.16 12.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Proteasome_A_N PF10584.4 EMD61887.1 - 1.5 8.2 4.0 25 4.3 0.2 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature C2 PF00168.25 EMD61888.1 - 2.4e-18 65.7 0.1 3.3e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 EMD61888.1 - 0.022 14.5 0.0 0.075 12.8 0.0 1.9 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Aminotran_3 PF00202.16 EMD61889.1 - 2e-105 352.4 0.0 2.4e-105 352.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMD61889.1 - 9.2e-06 25.0 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMD61889.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_membrane PF00664.18 EMD61890.1 - 1.8e-50 171.8 36.6 9.8e-31 107.1 13.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EMD61890.1 - 1.9e-49 167.5 1.1 3.8e-28 98.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EMD61890.1 - 1.4e-08 35.0 0.4 0.12 12.3 0.0 4.4 2 2 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EMD61890.1 - 2.3e-06 26.8 0.0 0.002 17.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 EMD61890.1 - 2.7e-06 26.8 0.7 0.036 13.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMD61890.1 - 4.1e-06 26.7 0.2 0.091 12.7 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EMD61890.1 - 7.7e-06 26.4 1.1 0.099 13.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 EMD61890.1 - 1.2e-05 24.7 6.3 0.088 12.0 0.8 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMD61890.1 - 2.4e-05 24.3 0.1 0.11 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMD61890.1 - 0.00076 18.7 0.8 0.39 9.8 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMD61890.1 - 0.0021 18.4 10.1 0.091 13.0 0.2 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EMD61890.1 - 0.0026 17.2 0.1 0.54 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD61890.1 - 0.0056 17.4 5.6 1.5 9.6 0.4 3.3 2 2 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 EMD61890.1 - 0.0061 15.2 0.2 0.87 8.1 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EMD61890.1 - 0.0067 15.8 2.7 0.53 9.6 0.2 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EMD61890.1 - 0.031 14.4 1.9 9 6.4 0.0 3.4 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EMD61890.1 - 0.032 13.7 6.7 1.1 8.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EMD61890.1 - 0.038 13.7 0.3 0.56 10.0 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EMD61890.1 - 0.041 14.1 0.0 13 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EMD61890.1 - 0.045 12.7 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 EMD61890.1 - 0.062 11.8 0.2 16 3.9 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ArgK PF03308.11 EMD61890.1 - 0.067 11.9 4.7 1.3 7.7 0.1 2.8 3 0 0 3 3 3 0 ArgK protein AAA_28 PF13521.1 EMD61890.1 - 0.07 13.0 4.1 0.076 12.9 0.0 3.0 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 EMD61890.1 - 0.093 12.4 0.4 15 5.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EMD61890.1 - 0.094 12.2 0.0 6 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EMD61890.1 - 0.2 11.4 11.2 0.63 9.8 0.2 3.3 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EMD61890.1 - 0.47 9.9 3.4 21 4.5 0.1 3.3 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EMD61890.1 - 2.4 7.9 12.6 0.14 11.9 0.2 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 FANCI_HD1 PF14679.1 EMD61892.1 - 0.16 11.7 0.2 0.37 10.5 0.1 1.7 1 1 0 1 1 1 0 FANCI helical domain 1 Gamma-thionin PF00304.15 EMD61893.1 - 0.026 14.5 18.0 0.61 10.1 4.1 2.3 2 0 0 2 2 2 0 Gamma-thionin family Prokineticin PF06607.6 EMD61893.1 - 0.079 13.0 0.5 0.079 13.0 0.4 2.7 2 1 1 3 3 3 0 Prokineticin LCE PF14672.1 EMD61893.1 - 0.12 12.8 19.2 0.19 12.2 4.4 2.5 2 1 0 2 2 2 0 Late cornified envelope Nodulin_late PF07127.6 EMD61893.1 - 0.36 10.9 5.3 9 6.5 0.1 2.2 2 0 0 2 2 2 0 Late nodulin protein Colipase-like PF15083.1 EMD61893.1 - 4.8 7.1 6.0 19 5.2 0.6 2.1 2 0 0 2 2 2 0 Colipase-like DND1_DSRM PF14709.1 EMD61894.1 - 0.023 14.9 1.0 0.07 13.4 0.7 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 YfhD PF14151.1 EMD61894.1 - 0.077 13.1 0.8 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 YfhD-like protein dsrm PF00035.20 EMD61894.1 - 0.079 13.5 0.1 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif Proteasome PF00227.21 EMD61894.1 - 0.088 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome subunit DNA_pol_E_B PF04042.11 EMD61897.1 - 3.4e-45 153.8 0.0 4.6e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Lipase_3 PF01764.20 EMD61899.1 - 2.8e-33 114.5 0.0 4.7e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EMD61899.1 - 0.0011 18.4 0.0 0.0055 16.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EMD61899.1 - 0.0011 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD61899.1 - 0.0037 17.1 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMD61899.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase PGAP1 PF07819.8 EMD61899.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 EMD61899.1 - 0.046 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 EMD61899.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DAHP_synth_1 PF00793.15 EMD61900.1 - 1.1e-97 325.9 0.1 1.3e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AP_endonuc_2 PF01261.19 EMD61901.1 - 1.7e-30 105.9 0.0 2.1e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short PF00106.20 EMD61902.1 - 3.9e-20 72.4 0.0 1.2e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD61902.1 - 1.4e-07 31.5 0.0 0.00041 20.2 0.0 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD61902.1 - 7.1e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD61902.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD61902.1 - 0.022 13.8 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Rad60-SLD PF11976.3 EMD61903.1 - 2.6e-23 81.4 0.0 3.3e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMD61903.1 - 8.3e-06 25.1 0.0 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Beta_helix PF13229.1 EMD61903.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Right handed beta helix region BSMAP PF12280.3 EMD61903.1 - 0.48 10.2 2.7 0.94 9.3 0.9 1.9 2 0 0 2 2 2 0 Brain specific membrane anchored protein BRF1 PF07741.8 EMD61903.1 - 4 7.7 8.0 2.6 8.3 2.9 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LSM PF01423.17 EMD61904.1 - 1.1e-17 63.3 0.0 1.2e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD61904.1 - 0.00072 19.4 0.0 0.00087 19.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Attractin PF08037.6 EMD61905.1 - 0.0005 19.7 0.6 0.0011 18.6 0.4 1.6 1 0 0 1 1 1 1 Attractin family p450 PF00067.17 EMD61906.1 - 2.4e-26 92.3 0.0 3e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMD61907.1 - 1e-33 116.5 0.0 1.4e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SR-25 PF10500.4 EMD61908.1 - 1.9 7.9 34.8 0.14 11.5 7.3 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 EMD61908.1 - 3.6 7.1 15.6 0.12 12.0 5.3 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit E1-E2_ATPase PF00122.15 EMD61909.1 - 1e-64 217.7 8.3 5.3e-64 215.4 4.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD61909.1 - 3.7e-45 153.7 6.2 3.7e-45 153.7 4.3 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD61909.1 - 1.6e-31 110.3 0.0 1.2e-30 107.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD61909.1 - 2.4e-23 81.8 0.0 5.8e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMD61909.1 - 1.1e-20 72.8 0.0 3.5e-20 71.2 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMD61909.1 - 9e-17 61.8 0.0 2.6e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD61909.1 - 3.7e-08 33.2 0.6 2.5e-06 27.2 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMD61909.1 - 0.0028 17.9 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Response_reg PF00072.19 EMD61910.1 - 4.8e-20 71.6 0.1 1.4e-19 70.1 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMD61910.1 - 4.4e-19 68.2 0.0 9.8e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD61910.1 - 4.2e-06 26.6 0.1 1.3e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peptidase_M32 PF02074.10 EMD61910.1 - 0.042 12.4 0.0 0.064 11.8 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Apolipoprotein PF01442.13 EMD61910.1 - 0.056 12.9 1.0 0.33 10.4 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FeoC PF09012.5 EMD61910.1 - 0.2 11.4 0.0 0.92 9.2 0.0 2.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator HATPase_c_3 PF13589.1 EMD61910.1 - 0.2 11.2 0.1 0.58 9.8 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stk19 PF10494.4 EMD61911.1 - 1.2e-52 178.8 0.0 2e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DAGAT PF03982.8 EMD61912.1 - 6.2e-99 330.4 0.0 8.2e-99 330.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EMD61912.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Rer1 family adh_short_C2 PF13561.1 EMD61914.1 - 3.4e-26 92.4 0.1 4.2e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD61914.1 - 1.4e-20 73.8 0.9 2.1e-20 73.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD61914.1 - 9.1e-07 28.7 0.3 1.5e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EMD61914.1 - 0.025 14.9 0.4 0.28 11.6 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMD61914.1 - 0.042 14.1 0.5 0.084 13.1 0.3 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EMD61914.1 - 0.049 13.2 0.3 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2884 PF11101.3 EMD61914.1 - 0.073 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Esterase PF00756.15 EMD61915.1 - 7.1e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMD61915.1 - 0.00024 20.4 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMD61915.1 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD61915.1 - 0.033 13.9 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD61915.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EMD61916.1 - 3.4e-92 309.8 0.2 2.1e-82 277.5 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD61916.1 - 1.7e-13 50.6 0.3 3.4e-13 49.6 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD61916.1 - 2.4e-05 24.1 0.2 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD61916.1 - 0.0049 16.1 0.1 0.0091 15.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Conotoxin PF02950.12 EMD61918.1 - 0.00047 20.8 1.5 0.00064 20.4 1.0 1.2 1 0 0 1 1 1 1 Conotoxin HeLo PF14479.1 EMD61919.1 - 5e-40 137.5 0.0 3.7e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 Prion-inhibition and propagation T6SS-SciN PF12790.2 EMD61919.1 - 0.0043 16.6 0.1 0.76 9.3 0.0 2.3 2 0 0 2 2 2 2 Type VI secretion lipoprotein DUF1556 PF07590.6 EMD61919.1 - 2.3 8.5 6.7 3.3 8.0 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1556) TPR_12 PF13424.1 EMD61920.1 - 7.4e-43 144.3 14.0 5.8e-11 42.1 0.2 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMD61920.1 - 2.9e-36 122.3 24.9 0.00018 21.3 0.1 8.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMD61920.1 - 5.2e-24 82.1 0.0 0.085 12.8 0.0 9.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMD61920.1 - 8.1e-23 80.5 0.2 0.00029 21.4 0.0 6.2 3 2 4 7 7 7 6 Tetratricopeptide repeat HET PF06985.6 EMD61920.1 - 5.6e-22 78.3 4.1 1.2e-19 70.8 2.8 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_20 PF14561.1 EMD61920.1 - 5.7e-20 71.2 18.0 0.062 13.4 0.1 8.7 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61920.1 - 4.3e-18 64.1 8.8 0.14 12.8 0.0 8.7 2 1 6 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMD61920.1 - 6.5e-18 63.3 4.8 0.2 11.9 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD61920.1 - 8.3e-18 63.8 1.5 0.00062 19.3 0.0 5.4 2 1 1 5 5 5 4 TPR repeat TPR_6 PF13174.1 EMD61920.1 - 3.2e-17 61.7 0.6 0.78 10.3 0.0 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61920.1 - 8e-17 61.3 11.4 0.0015 18.8 0.1 6.9 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61920.1 - 7.7e-14 50.3 0.0 0.83 9.5 0.0 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD61920.1 - 2.3e-12 46.8 7.1 0.0013 18.8 0.5 5.2 1 1 5 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMD61920.1 - 1.4e-09 37.1 0.0 4.9 6.9 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD61920.1 - 1.9e-09 36.7 0.0 3.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.9 EMD61920.1 - 4.6e-09 35.8 28.3 1.8 9.2 0.1 8.8 8 0 0 8 8 7 4 Tetratricopeptide repeat PPR PF01535.15 EMD61920.1 - 3.4e-08 32.9 0.0 15 5.8 0.0 8.0 8 0 0 8 8 8 0 PPR repeat PPR_3 PF13812.1 EMD61920.1 - 3.6e-08 33.0 0.0 19 5.8 0.0 7.6 7 0 0 7 7 7 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 EMD61920.1 - 6.9e-08 31.8 0.4 7.9 6.0 0.0 7.0 7 0 0 7 7 7 0 PPR repeat MORN_2 PF07661.8 EMD61920.1 - 1.1e-05 24.8 0.1 36 4.8 0.0 6.8 7 0 0 7 7 7 0 MORN repeat variant TPR_7 PF13176.1 EMD61920.1 - 4.3e-05 22.9 11.7 1.9 8.4 0.0 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat MurB_C PF02873.11 EMD61920.1 - 0.00024 20.8 4.4 3.1 7.6 0.1 4.4 1 1 3 4 4 4 2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain AAA_16 PF13191.1 EMD61920.1 - 0.0004 20.4 3.1 0.00067 19.6 0.2 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD61920.1 - 0.00073 19.6 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD61920.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WbqC PF08889.6 EMD61920.1 - 0.0027 17.1 2.8 7.3 5.9 0.0 4.0 1 1 2 5 5 5 0 WbqC-like protein family THOC7 PF05615.8 EMD61920.1 - 0.0091 16.2 0.2 0.029 14.6 0.1 1.9 1 0 0 1 1 1 1 Tho complex subunit 7 HTH_3 PF01381.17 EMD61920.1 - 0.014 15.1 0.1 0.085 12.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix NUMOD1 PF07453.8 EMD61920.1 - 0.11 12.3 0.2 0.31 10.9 0.1 1.9 2 0 0 2 2 1 0 NUMOD1 domain Peptidase_M50B PF13398.1 EMD61921.1 - 1.2e-55 187.9 17.6 1.6e-55 187.6 12.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EMD61921.1 - 0.017 14.1 1.6 0.069 12.1 1.1 2.2 1 1 0 1 1 1 0 Peptidase family M50 Patched PF02460.13 EMD61921.1 - 1 7.2 4.4 1.4 6.7 3.1 1.3 1 0 0 1 1 1 0 Patched family Wzy_C PF04932.10 EMD61921.1 - 4.9 6.9 13.0 22 4.7 5.7 2.5 2 1 0 2 2 2 0 O-Antigen ligase Sugar_tr PF00083.19 EMD61922.1 - 9.9e-126 419.9 20.4 1.1e-125 419.7 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD61922.1 - 1.8e-22 79.5 38.3 2.6e-16 59.3 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.1 EMD61922.1 - 0.0017 18.4 1.9 0.0017 18.4 1.3 3.4 4 1 1 5 5 5 1 Protein of unknown function (DUF4064) PIRT PF15099.1 EMD61922.1 - 0.22 10.7 2.9 0.14 11.3 0.4 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family YrhC PF14143.1 EMD61922.1 - 5.9 6.9 8.0 4.7 7.2 0.7 3.1 3 0 0 3 3 3 0 YrhC-like protein Zn_clus PF00172.13 EMD61923.1 - 7.1e-07 29.0 8.7 1.5e-06 27.9 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD61923.1 - 0.00011 21.2 0.1 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FimP PF09766.4 EMD61925.1 - 6e-18 65.0 21.6 1.3e-17 63.9 10.1 2.1 2 0 0 2 2 2 2 Fms-interacting protein HALZ PF02183.13 EMD61925.1 - 0.015 15.0 8.1 1.3 8.7 0.0 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper HNOBA PF07701.9 EMD61925.1 - 0.21 10.7 8.6 0.12 11.5 2.3 2.1 2 0 0 2 2 2 0 Heme NO binding associated U1snRNP70_N PF12220.3 EMD61925.1 - 0.63 10.3 10.0 0.66 10.3 1.9 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF349 PF03993.7 EMD61925.1 - 3.2 7.9 11.0 0.59 10.3 3.4 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) SNF2_N PF00176.18 EMD61926.1 - 3.4e-55 186.9 0.0 8.4e-55 185.6 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EMD61926.1 - 2.5e-09 36.8 9.1 6.7e-09 35.4 6.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD61926.1 - 1.4e-08 34.2 9.8 3.6e-08 32.9 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD61926.1 - 1.1e-07 31.4 7.1 2.5e-07 30.2 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD61926.1 - 6.1e-07 29.3 10.6 1.6e-06 28.0 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD61926.1 - 3.2e-06 26.7 8.8 7.1e-06 25.6 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMD61926.1 - 0.00017 21.6 10.7 0.00054 20.0 7.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMD61926.1 - 0.0023 17.7 7.8 0.0052 16.6 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMD61926.1 - 0.012 15.2 7.1 0.045 13.4 4.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EMD61926.1 - 0.026 14.0 3.6 0.072 12.6 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Fer4_11 PF13247.1 EMD61926.1 - 0.031 14.1 2.8 0.069 13.0 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Helicase_C PF00271.26 EMD61926.1 - 0.057 13.2 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 1 0 Helicase conserved C-terminal domain Baculo_IE-1 PF05290.6 EMD61926.1 - 0.079 12.6 3.7 0.18 11.5 2.6 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MAGE_N PF12440.3 EMD61926.1 - 0.68 10.2 16.0 2.4 8.4 11.1 1.9 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DZR PF12773.2 EMD61926.1 - 0.95 9.3 5.6 2.7 7.9 3.9 1.8 1 0 0 1 1 1 0 Double zinc ribbon Sod_Fe_C PF02777.13 EMD61928.1 - 8.4e-16 57.7 0.1 2e-06 27.5 0.0 3.1 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain RhoGAP PF00620.22 EMD61931.1 - 2.5e-41 140.8 0.1 4.9e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EMD61931.1 - 2.7e-12 46.8 0.1 5.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMD61931.1 - 2e-07 31.2 0.0 4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Dpoe2NT PF12213.3 EMD61931.1 - 0.0035 17.2 0.1 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal PH_8 PF15409.1 EMD61931.1 - 0.0073 16.3 0.1 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Host_attach PF10116.4 EMD61931.1 - 6.9 6.8 10.6 3.1 8.0 0.1 3.1 2 1 1 3 3 3 0 Protein required for attachment to host cells Ribosomal_S13 PF00416.17 EMD61932.1 - 6.8e-23 81.1 0.3 8e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EMD61933.1 - 3.9e-47 160.3 1.0 4.7e-47 160.0 0.7 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EMD61934.1 - 4.5e-45 153.1 0.0 2.4e-44 150.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD61934.1 - 5.6e-28 96.6 0.0 1e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD61934.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMD61934.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit An_peroxidase PF03098.10 EMD61935.1 - 1.5e-77 261.2 0.0 2.8e-75 253.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EMD61935.1 - 1.9e-09 36.5 0.1 8.6e-08 31.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EMD61936.1 - 6.7e-108 360.2 1.0 8.5e-108 359.9 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_61 PF03443.9 EMD61937.1 - 2.1e-61 207.4 0.1 3.4e-61 206.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMD61937.1 - 9.3e-11 41.2 13.6 1.8e-10 40.2 7.8 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain WSC PF01822.14 EMD61938.1 - 2.8e-09 36.7 0.3 2.8e-09 36.7 0.2 2.4 2 1 1 3 3 3 1 WSC domain GFO_IDH_MocA PF01408.17 EMD61939.1 - 1.4e-19 70.7 0.1 2.9e-19 69.7 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMD61939.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EMD61939.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EMD61940.1 - 3.1e-21 75.4 0.1 7e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD61940.1 - 0.0018 18.1 14.7 0.0035 17.2 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2800 PF10926.3 EMD61941.1 - 0.031 13.4 1.9 0.036 13.1 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) AAA_5 PF07728.9 EMD61941.1 - 0.037 13.7 0.6 0.066 12.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HutP PF09021.6 EMD61941.1 - 0.073 13.2 0.5 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 HutP DUF148 PF02520.12 EMD61941.1 - 0.18 11.5 4.3 11 5.8 1.8 2.5 1 1 2 3 3 3 0 Domain of unknown function DUF148 DUF826 PF05696.6 EMD61941.1 - 0.39 10.8 3.4 1.1 9.4 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF826) Phage_GP20 PF06810.6 EMD61941.1 - 0.4 10.0 7.9 1.3 8.4 5.4 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 ThiS PF02597.15 EMD61941.1 - 0.72 10.3 4.1 1.4 9.3 0.1 2.5 1 1 1 2 2 2 0 ThiS family Prothymosin PF03247.9 EMD61941.1 - 1.1 9.4 8.5 0.16 12.1 3.1 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family FliT PF05400.8 EMD61941.1 - 1.5 9.2 13.2 3.5 8.1 3.5 2.3 2 0 0 2 2 2 0 Flagellar protein FliT HCMV_UL139 PF12507.3 EMD61941.1 - 2 8.6 5.4 7.3 6.7 0.8 2.3 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF883 PF05957.8 EMD61941.1 - 5.1 7.5 8.7 4.5 7.7 1.4 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1180 PF06679.7 EMD61942.1 - 4.4 7.1 10.9 6.5 6.6 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Clathrin PF00637.15 EMD61943.1 - 3.8e-202 662.0 30.8 1e-35 122.4 1.2 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EMD61943.1 - 4e-28 97.0 0.1 2.9e-27 94.3 0.1 2.7 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EMD61943.1 - 1.5e-08 34.4 2.8 0.0062 16.7 0.1 5.4 5 0 0 5 5 5 2 Clathrin propeller repeat TPR_2 PF07719.12 EMD61943.1 - 0.00084 19.0 1.5 5 7.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD61943.1 - 0.0011 19.3 12.9 7.7 7.4 0.1 9.3 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD61943.1 - 0.0025 18.0 0.2 22 5.4 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD61943.1 - 0.0066 16.1 6.5 23 5.0 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD61943.1 - 0.04 13.6 7.0 22 5.1 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD61943.1 - 0.053 13.1 1.5 20 5.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3812 PF12757.2 EMD61944.1 - 7.5e-38 129.3 19.7 7.5e-38 129.3 13.7 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 EMD61945.1 - 3.1e-28 99.0 0.0 5e-27 95.1 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMD61945.1 - 1.7e-12 47.0 0.1 3.3e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMD61945.1 - 4.7e-05 23.4 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EMD61945.1 - 0.0019 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EMD61945.1 - 0.0081 14.9 0.3 0.014 14.1 0.1 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EMD61945.1 - 0.01 15.4 0.1 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMD61945.1 - 0.13 12.3 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate CMAS PF02353.15 EMD61946.1 - 1.6e-63 214.3 0.1 2e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMD61946.1 - 2.8e-12 46.6 0.0 4.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD61946.1 - 3.5e-09 37.0 0.0 7.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD61946.1 - 9e-05 22.7 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD61946.1 - 0.0001 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD61946.1 - 0.00047 20.5 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD61946.1 - 0.00066 20.2 0.0 0.0017 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMD61946.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EMD61946.1 - 0.0068 15.7 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EMD61946.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMD61946.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain INSIG PF07281.7 EMD61947.1 - 8.8e-45 152.4 0.1 1.3e-44 151.8 0.1 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GTP_EFTU PF00009.22 EMD61948.1 - 7.4e-39 133.1 0.0 1.2e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EMD61948.1 - 2.7e-36 123.4 0.2 5.8e-36 122.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EMD61948.1 - 3.3e-12 46.3 0.3 7e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD61948.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMD61948.1 - 0.074 12.8 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Connexin_CCC PF10582.4 EMD61948.1 - 0.25 11.2 0.4 0.57 10.0 0.3 1.6 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain RabGAP-TBC PF00566.13 EMD61949.1 - 1.8e-22 79.8 0.0 2.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RhoGEF PF00621.15 EMD61953.1 - 1e-29 103.7 2.7 2.1e-29 102.6 0.3 2.4 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EMD61953.1 - 2.2e-06 27.3 0.3 2.2e-06 27.3 0.2 2.6 3 0 0 3 3 3 2 BAR domain GrpE PF01025.14 EMD61953.1 - 0.065 12.7 0.9 0.16 11.5 0.6 1.6 1 0 0 1 1 1 0 GrpE Peptidase_M16_C PF05193.16 EMD61954.1 - 7.2e-25 87.7 0.0 2.4e-19 69.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMD61954.1 - 0.00011 21.9 0.0 0.00039 20.2 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DDE_Tnp_IS1 PF03400.8 EMD61954.1 - 0.024 14.7 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 IS1 transposase WD40 PF00400.27 EMD61955.1 - 9.7e-28 95.0 16.5 7.8e-07 28.7 0.2 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EMD61955.1 - 1.6e-11 44.0 0.3 4.5e-11 42.5 0.2 1.8 1 0 0 1 1 1 1 NLE (NUC135) domain Zw10 PF06248.8 EMD61955.1 - 8.6e-09 34.0 9.5 3.9e-07 28.6 6.6 2.8 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Nup160 PF11715.3 EMD61955.1 - 5.6e-08 31.3 7.2 0.0029 15.8 0.2 3.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Dsl1_C PF11989.3 EMD61955.1 - 1.5e-06 27.5 0.1 9.8e-05 21.6 0.0 2.6 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Nop14 PF04147.7 EMD61955.1 - 0.0048 14.8 12.0 0.0098 13.8 8.3 1.4 1 0 0 1 1 1 1 Nop14-like family DUF2808 PF10989.3 EMD61955.1 - 0.12 12.0 0.0 20 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Trm112p PF03966.11 EMD61956.1 - 2.3e-11 43.8 0.4 1.2e-10 41.6 0.3 1.9 1 1 0 1 1 1 1 Trm112p-like protein Ribosomal_60s PF00428.14 EMD61956.1 - 0.016 15.5 1.0 0.021 15.2 0.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein LRRNT PF01462.13 EMD61956.1 - 0.085 12.3 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain IL11 PF07400.6 EMD61956.1 - 0.14 11.6 0.2 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 Interleukin 11 GMC_oxred_N PF00732.14 EMD61957.1 - 7.5e-31 107.3 0.1 7.8e-20 71.2 0.0 3.1 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD61957.1 - 1.8e-23 83.3 0.0 2.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMD61957.1 - 0.0005 20.0 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD61957.1 - 0.00061 18.7 0.1 0.012 14.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD61957.1 - 0.0081 16.0 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD61957.1 - 0.017 14.0 0.4 0.038 12.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EMD61957.1 - 0.025 13.6 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMD61957.1 - 0.04 12.8 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EMD61957.1 - 0.048 13.0 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 EMD61957.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 EMD61957.1 - 0.2 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMD61957.1 - 0.27 9.6 0.1 0.59 8.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EMD61957.1 - 0.28 10.2 0.7 0.58 9.1 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase PMM PF03332.8 EMD61958.1 - 5.8e-104 346.4 0.2 6.8e-104 346.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EMD61958.1 - 0.00042 19.9 0.0 0.0018 17.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EMD61958.1 - 0.0031 16.8 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EMD61958.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2608 PF11019.3 EMD61958.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DNA_pol_A_exo1 PF01612.15 EMD61959.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 EMD61959.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LSM PF01423.17 EMD61960.1 - 8e-21 73.3 0.1 9.5e-21 73.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain RNA_bind_2 PF10133.4 EMD61960.1 - 0.058 13.4 0.2 0.19 11.8 0.1 1.9 1 1 1 2 2 2 0 Predicted RNA-binding protein HMG_box PF00505.14 EMD61961.1 - 6.8e-13 48.6 0.1 1.4e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.25 EMD61961.1 - 1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EMD61961.1 - 3.9e-09 36.7 0.2 8e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.12 EMD61961.1 - 1.7e-06 27.7 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3074 PF11274.3 EMD61962.1 - 3.2e-26 92.0 0.6 6.6e-26 91.0 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) ENT PF03735.9 EMD61962.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 ENT domain FKS1_dom1 PF14288.1 EMD61963.1 - 0.43 10.5 3.1 0.67 9.8 0.4 2.4 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DIOX_N PF14226.1 EMD61964.1 - 5.1e-28 97.9 0.1 8.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD61964.1 - 4.6e-16 58.9 0.1 1.3e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1685 PF07939.6 EMD61964.1 - 0.097 12.3 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) DUF3602 PF12223.3 EMD61966.1 - 7.6e-20 71.0 11.1 1.9e-17 63.4 0.9 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Sec10 PF07393.6 EMD61969.1 - 3.8e-161 537.7 0.1 5.9e-161 537.1 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EMD61969.1 - 4.4e-06 26.1 0.0 8.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD61969.1 - 3.9e-05 23.2 0.0 8.6e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like SWIB PF02201.13 EMD61970.1 - 5.6e-25 86.8 0.1 9.3e-25 86.1 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EMD61970.1 - 4.5e-13 48.7 0.9 9.2e-13 47.7 0.4 1.8 2 0 0 2 2 2 1 DEK C terminal domain ARGLU PF15346.1 EMD61970.1 - 0.22 11.2 4.7 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Ribosomal_60s PF00428.14 EMD61970.1 - 9.1 6.7 14.7 3.2 8.2 3.1 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein Tropomyosin_1 PF12718.2 EMD61972.1 - 9.8e-48 161.6 28.7 1.1e-47 161.4 19.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EMD61972.1 - 1.3e-10 40.7 28.3 3.8e-06 26.1 3.7 2.9 1 1 2 3 3 3 3 Tropomyosin TelA PF05816.6 EMD61972.1 - 0.00059 18.6 4.6 0.00059 18.6 3.2 2.0 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) Seryl_tRNA_N PF02403.17 EMD61972.1 - 0.00066 19.6 23.2 0.16 11.9 3.3 3.1 1 1 2 3 3 3 3 Seryl-tRNA synthetase N-terminal domain KLRAQ PF10205.4 EMD61972.1 - 0.00073 19.5 8.2 0.00073 19.5 5.7 2.4 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 EMD61972.1 - 0.00075 19.3 27.6 0.055 13.3 1.8 3.0 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EMD61972.1 - 0.0012 18.5 21.8 0.033 13.9 8.2 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Striatin PF08232.7 EMD61972.1 - 0.0014 18.9 23.0 0.048 13.9 7.7 2.1 1 1 1 2 2 2 2 Striatin family ADIP PF11559.3 EMD61972.1 - 0.0015 18.4 26.6 0.016 15.0 6.4 2.3 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EMD61972.1 - 0.0025 17.6 24.9 0.017 14.9 5.8 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) IFT46_B_C PF12317.3 EMD61972.1 - 0.0041 16.5 3.5 0.0041 16.5 2.4 1.8 1 1 1 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal DivIC PF04977.10 EMD61972.1 - 0.0051 16.2 2.6 0.0051 16.2 1.8 4.1 1 1 2 4 4 4 1 Septum formation initiator DUF3450 PF11932.3 EMD61972.1 - 0.0075 15.5 22.4 0.049 12.8 6.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF4200 PF13863.1 EMD61972.1 - 0.0075 16.2 31.6 0.21 11.5 6.8 3.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) ERM PF00769.14 EMD61972.1 - 0.0078 15.7 30.1 0.052 13.0 7.7 2.0 1 1 0 2 2 2 2 Ezrin/radixin/moesin family IncA PF04156.9 EMD61972.1 - 0.0087 15.6 24.3 0.1 12.2 16.9 2.0 1 1 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 EMD61972.1 - 0.0096 13.7 28.1 0.12 10.0 7.6 1.9 1 1 1 2 2 2 2 Myosin tail GAS PF13851.1 EMD61972.1 - 0.012 14.7 25.3 0.029 13.5 10.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EMD61972.1 - 0.012 15.6 16.2 0.27 11.3 2.6 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EMD61972.1 - 0.013 15.4 26.9 0.92 9.5 1.2 4.4 2 2 1 4 4 4 0 bZIP transcription factor SlyX PF04102.7 EMD61972.1 - 0.014 15.7 17.0 0.028 14.7 2.8 2.9 2 1 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 EMD61972.1 - 0.021 14.6 30.2 0.39 10.5 7.9 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EMD61972.1 - 0.029 13.5 3.8 0.17 11.0 2.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EMD61972.1 - 0.037 13.8 16.5 0.052 13.3 2.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Cast PF10174.4 EMD61972.1 - 0.041 11.9 23.9 0.049 11.6 16.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Laminin_I PF06008.9 EMD61972.1 - 0.047 13.0 18.8 0.13 11.5 12.6 2.0 1 1 0 1 1 1 0 Laminin Domain I Atg14 PF10186.4 EMD61972.1 - 0.053 12.4 24.1 0.033 13.1 5.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BRE1 PF08647.6 EMD61972.1 - 0.055 13.4 24.4 0.05 13.5 8.4 2.5 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Herpes_pp85 PF04637.7 EMD61972.1 - 0.056 11.7 3.4 0.024 12.9 0.6 1.6 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4618 PF15397.1 EMD61972.1 - 0.066 12.5 19.8 0.77 9.0 1.5 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) Spectrin PF00435.16 EMD61972.1 - 0.068 13.4 22.6 0.19 12.0 6.0 2.4 1 1 0 2 2 2 0 Spectrin repeat CENP-Q PF13094.1 EMD61972.1 - 0.07 13.1 30.7 0.68 9.9 8.0 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 EMD61972.1 - 0.078 12.7 28.5 0.21 11.3 5.9 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.1 EMD61972.1 - 0.083 12.0 22.9 0.27 10.3 8.3 2.0 1 1 1 2 2 2 0 TMCO5 family LPP PF04728.8 EMD61972.1 - 0.085 12.6 0.3 0.72 9.7 0.0 2.7 2 2 0 2 2 1 0 Lipoprotein leucine-zipper APG6 PF04111.7 EMD61972.1 - 0.089 11.8 29.5 0.18 10.8 7.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 PspA_IM30 PF04012.7 EMD61972.1 - 0.1 11.9 25.8 1.1 8.5 5.9 2.5 1 1 1 2 2 2 0 PspA/IM30 family V_ATPase_I PF01496.14 EMD61972.1 - 0.11 10.2 16.0 0.13 10.0 10.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family EzrA PF06160.7 EMD61972.1 - 0.13 10.4 20.7 0.13 10.3 2.6 2.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Mnd1 PF03962.10 EMD61972.1 - 0.18 11.4 28.7 1 8.9 7.6 2.1 1 1 1 2 2 2 0 Mnd1 family Jnk-SapK_ap_N PF09744.4 EMD61972.1 - 0.2 11.6 23.3 0.24 11.3 9.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Mod_r PF07200.8 EMD61972.1 - 0.21 11.4 21.9 0.21 11.5 5.9 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 EMD61972.1 - 0.21 9.9 21.6 0.44 8.9 5.2 2.0 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 EMD61972.1 - 0.23 11.0 24.6 0.99 8.9 5.4 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 EMD61972.1 - 0.25 8.6 22.7 0.37 8.0 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EMD61972.1 - 0.25 10.7 24.4 1.5 8.2 6.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein TMP_2 PF06791.8 EMD61972.1 - 0.26 10.8 4.4 0.1 12.2 0.7 1.8 1 1 0 2 2 2 0 Prophage tail length tape measure protein Uso1_p115_C PF04871.8 EMD61972.1 - 0.28 11.1 21.7 0.93 9.4 10.9 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.4 EMD61972.1 - 0.28 11.3 19.2 2.3 8.4 3.4 3.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Orbi_VP5 PF00901.12 EMD61972.1 - 0.32 9.1 15.2 0.3 9.2 10.1 1.3 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF4201 PF13870.1 EMD61972.1 - 0.36 10.2 21.0 2.4 7.5 5.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lebercilin PF15619.1 EMD61972.1 - 0.36 10.2 25.4 0.91 8.9 6.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NPIP PF06409.6 EMD61972.1 - 0.37 9.5 7.2 0.46 9.1 5.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) WXG100 PF06013.7 EMD61972.1 - 0.37 10.8 12.2 8.4 6.4 0.0 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG PilJ PF13675.1 EMD61972.1 - 0.4 11.0 10.3 0.18 12.1 2.2 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_27 PF13514.1 EMD61972.1 - 0.41 8.2 23.9 1.2 6.6 5.4 2.0 1 1 1 2 2 2 0 AAA domain DUF4140 PF13600.1 EMD61972.1 - 0.43 11.0 20.3 0.65 10.4 3.9 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 EMD61972.1 - 0.47 10.2 14.4 1.6 8.5 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF869 PF05911.6 EMD61972.1 - 0.48 8.5 22.7 0.69 8.0 6.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF342 PF03961.8 EMD61972.1 - 0.5 8.7 22.4 0.32 9.3 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EMD61972.1 - 0.52 10.6 20.3 1.5 9.2 4.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF812 PF05667.6 EMD61972.1 - 0.65 8.4 25.1 2.8 6.3 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CDC37_N PF03234.9 EMD61972.1 - 0.66 10.2 19.5 2.8 8.2 13.5 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF904 PF06005.7 EMD61972.1 - 0.67 10.2 30.5 6.9 7.0 3.4 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF904) Kinetocho_Slk19 PF12709.2 EMD61972.1 - 0.83 9.7 25.8 3.2 7.8 6.9 3.5 2 2 1 3 3 3 0 Central kinetochore-associated HalX PF08663.5 EMD61972.1 - 0.85 9.6 0.1 0.85 9.6 0.0 4.3 2 2 2 4 4 4 0 HalX domain MS_channel PF00924.13 EMD61972.1 - 0.87 8.8 3.2 0.5 9.6 0.5 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel Nup54 PF13874.1 EMD61972.1 - 0.9 9.2 18.4 0.26 10.9 6.1 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.15 EMD61972.1 - 1 9.1 31.1 2.6 7.8 5.2 4.0 1 1 2 3 3 3 0 Prefoldin subunit Sec20 PF03908.8 EMD61972.1 - 1.1 8.9 8.4 0.57 9.9 0.8 2.4 2 1 0 2 2 2 0 Sec20 Syntaxin-6_N PF09177.6 EMD61972.1 - 1.1 9.6 16.8 1.4 9.3 2.6 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.4 EMD61972.1 - 1.2 7.4 21.4 0.29 9.4 4.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.6 EMD61972.1 - 1.3 7.6 24.3 0.95 8.0 5.2 2.0 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3166 PF11365.3 EMD61972.1 - 1.3 9.5 14.4 0.7 10.3 5.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Phage_GP20 PF06810.6 EMD61972.1 - 1.4 8.3 25.0 0.62 9.4 5.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 CCDC155 PF14662.1 EMD61972.1 - 1.4 8.4 28.2 1.3 8.5 7.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 ABC_tran PF00005.22 EMD61972.1 - 2 8.7 6.1 0.6 10.4 1.7 1.8 1 1 1 2 2 2 0 ABC transporter MAD PF05557.8 EMD61972.1 - 2.1 6.3 26.5 7.4 4.5 18.3 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF641 PF04859.7 EMD61972.1 - 2.2 8.0 20.7 0.22 11.2 3.6 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CASP_C PF08172.7 EMD61972.1 - 3.3 6.6 14.6 37 3.2 2.8 2.4 1 1 1 2 2 2 0 CASP C terminal Rop-like PF05082.8 EMD61972.1 - 3.3 7.2 9.0 2.2 7.8 0.2 3.4 4 0 0 4 4 3 0 Rop-like Prefoldin PF02996.12 EMD61972.1 - 3.4 7.3 23.9 2.6 7.7 1.4 3.7 2 1 1 4 4 4 0 Prefoldin subunit MbeD_MobD PF04899.7 EMD61972.1 - 4.5 7.2 11.5 1.2 9.1 0.3 3.5 3 1 1 4 4 4 0 MbeD/MobD like DUF724 PF05266.9 EMD61972.1 - 4.8 6.7 23.9 1.9 8.1 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Swi5 PF07061.6 EMD61972.1 - 5.6 6.8 15.3 7.6 6.3 1.2 3.3 2 1 0 2 2 2 0 Swi5 EHN PF06441.7 EMD61972.1 - 6.2 6.7 11.1 2.4 8.0 2.6 2.4 1 1 1 2 2 2 0 Epoxide hydrolase N terminus STAT_alpha PF01017.15 EMD61972.1 - 6.3 6.4 15.1 5.5e+02 0.1 10.5 2.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain Med4 PF10018.4 EMD61972.1 - 6.5 6.1 19.8 2.8 7.3 1.7 3.2 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2203 PF09969.4 EMD61972.1 - 6.6 6.9 15.4 3.1 8.0 2.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cortex-I_coil PF09304.5 EMD61972.1 - 6.9 6.7 23.7 11 6.1 4.1 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil FdhE PF04216.7 EMD61972.1 - 7.1 6.2 7.5 12 5.5 5.0 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Hemerythrin PF01814.18 EMD61972.1 - 7.3 6.7 9.3 18 5.5 1.7 2.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF4407 PF14362.1 EMD61972.1 - 8.2 5.2 20.8 13 4.6 14.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3994 PF13159.1 EMD61972.1 - 9.3 6.5 12.8 5.6 7.2 1.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) Nop25 PF09805.4 EMD61973.1 - 8.4e-35 119.8 17.5 8.4e-35 119.8 12.1 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4349 PF14257.1 EMD61973.1 - 0.43 9.7 8.0 0.1 11.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Nop14 PF04147.7 EMD61973.1 - 2.5 5.9 33.7 3.1 5.5 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family Prenyltrans PF00432.16 EMD61974.1 - 3e-29 100.2 7.9 5.8e-07 28.9 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMD61974.1 - 6.7e-20 71.5 0.0 1.2e-10 41.7 0.0 3.8 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMD61974.1 - 9.7e-06 25.5 0.0 2.9 7.9 0.0 4.0 2 1 1 3 3 3 3 Prenyltransferase-like A2M_comp PF07678.9 EMD61974.1 - 0.021 14.0 0.0 0.41 9.8 0.0 2.7 3 0 0 3 3 3 0 A-macroglobulin complement component RhoGAP PF00620.22 EMD61975.1 - 2.4e-17 62.9 0.2 6.6e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EMD61975.1 - 2.1e-15 56.6 0.3 1.7e-14 53.7 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EMD61975.1 - 2.7e-12 46.2 0.0 5.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sipho_Gp157 PF05565.6 EMD61975.1 - 0.052 13.1 0.7 6.4 6.3 0.1 2.7 2 0 0 2 2 2 0 Siphovirus Gp157 Syja_N PF02383.13 EMD61977.1 - 8.8e-89 297.4 0.0 1.2e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EMD61977.1 - 1.8e-23 83.7 0.2 1.8e-23 83.7 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family WW PF00397.21 EMD61978.1 - 5.8e-09 35.6 0.6 1.4e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EMD61978.1 - 0.0025 16.4 0.2 0.0042 15.6 0.1 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 EMD61978.1 - 0.3 10.7 2.1 0.53 9.9 1.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF1640 PF07798.6 EMD61979.1 - 4.9e-65 218.8 10.5 6.1e-65 218.5 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) His_kinase PF06580.8 EMD61979.1 - 0.62 10.0 3.0 1.6 8.7 0.1 2.4 2 1 0 2 2 2 0 Histidine kinase GreA_GreB_N PF03449.10 EMD61979.1 - 4.1 7.5 9.7 19 5.3 6.7 2.2 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal Mst1_SARAH PF11629.3 EMD61979.1 - 4.7 7.1 6.7 20 5.0 0.2 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Exonuc_VII_L PF02601.10 EMD61979.1 - 5.7 6.0 10.7 7.6 5.6 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit 14-3-3 PF00244.15 EMD61980.1 - 3e-110 366.8 1.0 4.1e-110 366.4 0.7 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 EMD61980.1 - 0.041 13.2 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) zf-CSL PF05207.8 EMD61981.1 - 8.1e-15 54.0 1.6 1.5e-14 53.2 1.1 1.5 1 1 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EMD61981.1 - 3.3e-10 39.5 1.5 5.3e-10 38.8 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1810 PF08837.6 EMD61981.1 - 0.12 11.9 0.1 0.43 10.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1810) HNH_2 PF13391.1 EMD61982.1 - 1e-06 28.4 0.1 2.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease RRM_1 PF00076.17 EMD61983.1 - 1.4e-09 37.4 0.0 3.9e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD61983.1 - 4.9e-08 32.7 0.1 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD61983.1 - 1.7e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EMD61983.1 - 0.00045 19.8 0.3 0.00082 19.0 0.0 1.6 2 0 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 EMD61983.1 - 0.034 13.8 0.6 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 DUF4523 PF15023.1 EMD61983.1 - 0.049 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Pkinase PF00069.20 EMD61984.1 - 5.9e-59 199.3 0.0 7e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61984.1 - 2.7e-34 118.4 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CPSase_L_D2 PF02786.12 EMD61985.1 - 7.3e-81 270.4 0.1 1.2e-80 269.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EMD61985.1 - 9.2e-66 221.0 0.0 1.5e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EMD61985.1 - 3.5e-35 120.4 0.0 7.7e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMD61985.1 - 2e-29 101.7 0.0 5e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EMD61985.1 - 3e-29 102.3 0.0 5.1e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EMD61985.1 - 1.1e-19 69.8 1.1 2.5e-19 68.6 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMD61985.1 - 8.7e-18 64.7 0.1 2.1e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD61985.1 - 9.3e-18 64.0 0.0 3.4e-17 62.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EMD61985.1 - 8.9e-11 41.2 1.8 5.9e-06 25.8 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EMD61985.1 - 1.1e-09 38.0 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EMD61985.1 - 1.5e-06 27.8 0.0 4.6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EMD61985.1 - 3.1e-06 26.6 0.0 6.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMD61985.1 - 5.3e-05 23.1 0.1 0.00014 21.7 0.0 1.7 2 0 0 2 2 1 1 ATP-grasp domain HlyD_3 PF13437.1 EMD61985.1 - 0.00016 22.0 0.0 0.57 10.5 0.0 3.3 4 0 0 4 4 3 2 HlyD family secretion protein HlyD PF00529.15 EMD61985.1 - 0.00032 20.1 0.1 0.019 14.2 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 EMD61985.1 - 0.00042 19.5 0.0 0.39 9.8 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein DUF912 PF06024.7 EMD61986.1 - 3.7 7.6 5.9 6.5 6.8 4.1 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) tRNA-synt_1d PF00750.14 EMD61987.1 - 1.6e-30 106.1 3.0 1.7e-14 53.4 0.1 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EMD61987.1 - 5.2e-13 48.9 0.6 3.6e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain ERM PF00769.14 EMD61988.1 - 0.0088 15.6 0.9 0.014 14.9 0.6 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.4 EMD61988.1 - 0.024 14.6 2.5 0.044 13.7 1.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF755 PF05501.6 EMD61988.1 - 0.14 12.2 0.1 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF755) DUF972 PF06156.8 EMD61988.1 - 0.21 11.9 7.5 1.8 8.9 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Peptidase_M20 PF01546.23 EMD61989.1 - 5.4e-20 71.7 0.1 7.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD61989.1 - 4.8e-19 68.1 0.1 8.4e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain UBA_4 PF14555.1 EMD61989.1 - 0.098 12.2 2.0 0.31 10.6 0.1 2.4 2 1 1 3 3 3 0 UBA-like domain Peptidase_M28 PF04389.12 EMD61989.1 - 0.11 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 M16C_assoc PF08367.6 EMD61990.1 - 2.1e-66 223.3 0.6 3.7e-66 222.4 0.1 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EMD61990.1 - 1.3e-30 106.5 0.0 2.3e-21 76.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMD61990.1 - 7.2e-07 29.0 0.2 3.5e-05 23.5 0.0 3.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) CAF-1_p150 PF11600.3 EMD61991.1 - 0.044 13.1 2.2 0.056 12.8 1.5 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1176 PF06674.6 EMD61991.1 - 1.2 8.2 4.1 1.4 7.9 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Taxilin PF09728.4 EMD61992.1 - 2.8e-45 154.7 31.9 4.1e-45 154.2 22.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Peptidase_S64 PF08192.6 EMD61992.1 - 2.8 6.1 12.0 4.4 5.5 8.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 UPF0242 PF06785.6 EMD61992.1 - 5.7 5.5 18.3 2.8 6.5 11.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) POR_N PF01855.14 EMD61992.1 - 7.9 5.9 10.3 11 5.4 2.2 2.2 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg peroxidase PF00141.18 EMD61993.1 - 2e-19 70.0 0.1 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase NMO PF03060.10 EMD61994.1 - 4.3e-73 246.3 2.3 5.1e-73 246.0 1.6 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMD61994.1 - 4.2e-08 32.4 0.0 1.5e-06 27.3 0.0 2.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMD61994.1 - 7.2e-05 21.7 1.5 0.00011 21.1 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FATC PF02260.15 EMD61994.1 - 0.0029 16.9 0.1 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 FATC domain PEP-utilizers PF00391.18 EMD61994.1 - 0.016 14.7 0.8 0.053 13.0 0.5 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Pkinase PF00069.20 EMD61995.1 - 2.7e-67 226.6 0.0 4.7e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD61995.1 - 1e-40 139.4 0.0 1.5e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD61995.1 - 1.1e-09 37.6 0.0 5.9e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD61995.1 - 0.0015 18.3 9.7 0.09 12.5 0.2 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EMD61995.1 - 0.0019 17.2 0.2 0.04 12.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMD61995.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 AA_permease PF00324.16 EMD61996.1 - 1.7e-139 465.2 34.4 2e-139 465.0 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD61996.1 - 5.2e-38 130.6 35.2 6.8e-38 130.2 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF373 PF04123.8 EMD61996.1 - 1.1 8.2 7.2 2.7 6.9 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Aldo_ket_red PF00248.16 EMD61997.1 - 3.2e-48 163.9 0.0 4.1e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 EMD61997.1 - 0.21 10.9 1.1 1.1 8.6 1.1 1.8 1 1 1 2 2 2 0 Poliovirus 3A protein like FKBP_C PF00254.23 EMD61998.1 - 1.1e-27 95.8 0.0 1.3e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1903 PF08991.5 EMD61999.1 - 4e-05 23.6 3.0 5.4e-05 23.2 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EMD61999.1 - 4.6e-05 23.2 2.6 9e-05 22.2 1.7 1.6 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EMD61999.1 - 0.95 9.2 5.0 2.3 8.0 3.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C3HC4_4 PF15227.1 EMD62000.1 - 1e-05 25.3 12.2 1e-05 25.3 8.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMD62000.1 - 3.4e-05 23.3 12.0 3.4e-05 23.3 8.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD62000.1 - 4.5e-05 23.3 12.7 4.5e-05 23.3 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD62000.1 - 6.3e-05 22.7 12.1 6.3e-05 22.7 8.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMD62000.1 - 0.00052 19.6 11.5 0.00052 19.6 8.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD62000.1 - 0.002 17.7 9.1 0.002 17.7 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PPV_E1_N PF00524.13 EMD62000.1 - 0.062 13.5 6.6 0.055 13.6 1.2 3.1 2 0 0 2 2 2 0 E1 Protein, N terminal domain zf-RING_UBOX PF13445.1 EMD62000.1 - 0.24 11.1 5.6 0.58 9.9 3.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EMD62000.1 - 0.74 9.6 8.1 0.16 11.8 1.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMD62000.1 - 2 8.5 10.5 3.7 7.7 4.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger FLO_LFY PF01698.11 EMD62000.1 - 2.2 7.0 6.5 7.6 5.2 4.5 2.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1406 PF07190.6 EMD62001.1 - 0.07 12.8 0.1 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) Cut8_N PF14482.1 EMD62001.1 - 0.48 10.4 2.8 0.87 9.6 0.5 2.1 1 1 1 2 2 2 0 Cut8 proteasome-binding domain ETC_C1_NDUFA5 PF04716.9 EMD62003.1 - 0.06 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region bZIP_1 PF00170.16 EMD62005.1 - 0.025 14.5 1.1 0.035 14.0 0.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor ArfGap PF01412.13 EMD62006.1 - 8.9e-38 128.6 0.1 8.9e-38 128.6 0.1 3.1 3 2 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 EMD62006.1 - 0.0036 17.0 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 EMD62007.1 - 1.7e-18 66.0 2.4 3.3e-18 65.1 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EMD62007.1 - 0.068 13.2 1.0 0.1 12.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EMD62007.1 - 0.46 10.1 5.9 0.45 10.1 1.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4279 PF14106.1 EMD62008.1 - 0.038 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Ndc80_HEC PF03801.8 EMD62008.1 - 0.1 12.0 1.7 0.14 11.5 1.2 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family PRA1 PF03208.14 EMD62010.1 - 8.7e-41 138.8 1.3 1.1e-40 138.5 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.26 EMD62011.1 - 6.8e-12 44.9 1.3 6.8e-12 44.9 0.9 2.0 2 1 0 2 2 2 1 DnaJ domain Mucin PF01456.12 EMD62012.1 - 0.024 14.3 16.6 0.066 12.9 11.5 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Fcf1 PF04900.7 EMD62013.1 - 1e-39 134.7 1.2 1.2e-39 134.4 0.1 1.6 2 0 0 2 2 2 1 Fcf1 PIN PF01850.16 EMD62013.1 - 0.24 11.7 2.1 4.4 7.6 0.4 2.3 1 1 1 2 2 2 0 PIN domain HlyIII PF03006.15 EMD62014.1 - 1.3e-58 198.0 23.8 1.7e-58 197.6 16.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related IF-2B PF01008.12 EMD62015.1 - 1.4e-71 240.7 0.7 1.7e-71 240.5 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family EF-hand_4 PF12763.2 EMD62016.1 - 2.2e-27 94.8 0.0 1.6e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EMD62016.1 - 6.8e-08 31.8 0.4 6.8e-08 31.8 0.3 3.3 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 EMD62016.1 - 0.00023 21.2 0.0 0.054 13.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair E3_binding PF02817.12 EMD62016.1 - 0.016 14.7 0.2 0.15 11.6 0.1 2.5 2 0 0 2 2 2 0 e3 binding domain EF-hand_6 PF13405.1 EMD62016.1 - 0.025 14.4 0.4 35 4.6 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain DUF1720 PF08226.6 EMD62016.1 - 0.081 13.0 158.3 0.014 15.4 26.2 6.8 4 2 2 6 6 6 0 Domain of unknown function (DUF1720) 2OG-FeII_Oxy_3 PF13640.1 EMD62017.1 - 6.6e-07 29.7 0.3 3.5e-06 27.4 0.2 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMD62017.1 - 0.0036 17.5 0.0 0.32 11.2 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin PF08613.6 EMD62018.1 - 3.6e-38 131.3 6.7 5.9e-22 78.6 0.4 2.9 3 0 0 3 3 3 2 Cyclin Proteasome PF00227.21 EMD62019.1 - 2.6e-49 167.0 0.2 3.1e-49 166.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_5 PF12695.2 EMD62020.1 - 3.9e-24 85.0 0.0 6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD62020.1 - 2e-17 63.8 0.0 3.1e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD62020.1 - 8.2e-07 28.8 0.0 0.00016 21.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EMD62020.1 - 2.3e-06 26.3 0.2 0.054 11.9 0.1 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMD62020.1 - 1.3e-05 24.5 0.0 2.6e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EMD62020.1 - 5.6e-05 22.9 0.0 0.0036 17.0 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EMD62020.1 - 0.00011 21.7 0.0 0.00035 20.0 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EMD62020.1 - 0.00021 20.9 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMD62020.1 - 0.00066 19.1 0.2 0.23 10.8 0.0 2.4 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EMD62020.1 - 0.00092 18.6 0.0 0.004 16.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 EMD62020.1 - 0.004 16.4 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF818 PF05677.7 EMD62020.1 - 0.0043 15.8 0.1 0.0059 15.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.8 EMD62020.1 - 0.044 13.3 0.1 0.16 11.4 0.1 2.0 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EMD62020.1 - 0.1 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PhoPQ_related PF10142.4 EMD62020.1 - 0.16 10.3 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein YTH PF04146.10 EMD62021.1 - 2.4e-58 195.7 0.0 5.9e-58 194.4 0.0 1.6 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.17 EMD62021.1 - 3.2e-07 29.8 0.0 6.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD62021.1 - 1.2e-06 28.4 0.0 2.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD62021.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_3 PF00933.16 EMD62022.1 - 5.2e-86 288.3 0.0 7.2e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD62022.1 - 5.1e-60 202.8 0.0 7.4e-59 199.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD62022.1 - 3.2e-18 65.4 0.2 6.8e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMD62022.1 - 0.0003 20.4 0.0 0.00095 18.8 0.0 1.8 2 0 0 2 2 2 1 PA14 domain Far-17a_AIG1 PF04750.9 EMD62023.1 - 1.9e-51 174.1 7.9 2.2e-51 173.9 5.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-C2H2_4 PF13894.1 EMD62024.1 - 0.047 14.0 0.2 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Prenyltrans PF00432.16 EMD62025.1 - 2.9e-57 189.8 11.0 4.2e-11 42.1 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMD62025.1 - 2e-30 105.4 0.1 9.8e-12 45.2 0.0 4.0 1 1 4 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMD62025.1 - 8.9e-09 35.3 0.1 0.058 13.4 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like RhoGAP PF00620.22 EMD62027.1 - 1.7e-30 105.6 0.0 1.7e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Hid1 PF12722.2 EMD62027.1 - 0.0014 16.4 4.7 0.0014 16.4 3.3 2.0 2 0 0 2 2 2 1 High-temperature-induced dauer-formation protein YfhO PF09586.5 EMD62027.1 - 0.048 11.6 3.3 0.063 11.2 2.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4557 PF15101.1 EMD62027.1 - 0.31 10.8 12.3 0.72 9.6 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2215 PF10225.4 EMD62027.1 - 2.9 7.2 4.5 8.9 5.6 3.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) MAP65_ASE1 PF03999.7 EMD62027.1 - 4.3 5.8 23.9 0.015 13.9 4.1 2.3 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.1 EMD62027.1 - 6.2 5.6 9.5 10 4.9 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) hDGE_amylase PF14701.1 EMD62028.1 - 2.4e-179 596.6 0.0 3.2e-179 596.2 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EMD62028.1 - 5.7e-113 377.3 0.1 1.2e-112 376.2 0.1 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EMD62028.1 - 8.9e-87 290.5 0.0 1.4e-86 289.8 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EMD62028.1 - 3.4e-24 84.5 0.3 9.7e-24 83.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EMD62028.1 - 1.8e-06 27.5 0.5 0.00014 21.4 0.2 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF2636 PF11120.3 EMD62029.1 - 0.056 12.9 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) DUF818 PF05677.7 EMD62029.1 - 0.065 11.9 0.0 0.067 11.9 0.0 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PRT_C PF08372.5 EMD62034.1 - 0.1 12.1 1.6 0.12 11.8 1.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Aldedh PF00171.17 EMD62036.1 - 8.2e-182 604.6 1.1 9.3e-182 604.4 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD62036.1 - 2.3e-05 23.3 0.2 7.3e-05 21.6 0.0 1.6 1 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMD62036.1 - 0.084 12.0 0.0 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glyco_transf_20 PF00982.16 EMD62037.1 - 1.1e-156 522.0 0.1 1.8e-156 521.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMD62037.1 - 2.2e-46 157.6 0.0 3.7e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Fer2_3 PF13085.1 EMD62040.1 - 1.3e-31 108.6 0.0 2.1e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EMD62040.1 - 2.5e-09 37.3 7.0 2.5e-09 37.3 4.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMD62040.1 - 1e-08 35.0 4.9 1e-08 35.0 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMD62040.1 - 0.00023 21.5 2.0 0.00023 21.5 1.4 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMD62040.1 - 0.00044 19.9 4.8 0.00044 19.9 3.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMD62040.1 - 0.00054 20.1 4.0 0.037 14.3 0.3 3.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer2 PF00111.22 EMD62040.1 - 0.0023 17.6 2.4 0.0094 15.6 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EMD62040.1 - 0.0048 17.2 4.7 0.0048 17.2 3.2 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EMD62040.1 - 0.62 10.6 0.1 0.62 10.6 0.1 3.0 4 0 0 4 4 4 0 4Fe-4S single cluster domain PMP1_2 PF08114.6 EMD62041.1 - 0.018 14.5 0.5 0.025 14.0 0.3 1.2 1 0 0 1 1 1 0 ATPase proteolipid family DUF443 PF04276.7 EMD62041.1 - 0.024 14.1 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Baculo_11_kDa PF06143.6 EMD62041.1 - 0.052 12.9 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4293 PF14126.1 EMD62041.1 - 0.053 13.4 0.1 0.054 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) SMP_2 PF10144.4 EMD62041.1 - 0.089 11.8 0.1 0.099 11.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin MSC PF09402.5 EMD62041.1 - 0.12 11.0 0.1 0.13 10.9 0.1 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RCR PF12273.3 EMD62041.1 - 0.15 12.6 2.6 0.21 12.1 1.8 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1560 PF07597.6 EMD62041.1 - 0.18 11.8 0.4 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) DUF3951 PF13131.1 EMD62041.1 - 0.25 11.1 1.8 0.34 10.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) EphA2_TM PF14575.1 EMD62041.1 - 0.39 11.1 1.5 0.58 10.5 1.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 EMD62041.1 - 1.7 8.8 4.0 2.4 8.4 2.8 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family APG5 PF04106.7 EMD62042.1 - 2.2e-60 203.4 0.0 2.9e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF3651 PF12371.3 EMD62043.1 - 0.047 13.6 0.1 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3651) cobW PF02492.14 EMD62044.1 - 3.5e-38 130.8 0.0 4.8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMD62044.1 - 0.00025 20.6 0.0 0.0054 16.4 0.0 2.7 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EMD62044.1 - 0.00091 18.9 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMD62044.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMD62044.1 - 0.015 15.4 0.0 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMD62044.1 - 0.025 14.1 0.1 0.54 9.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 EMD62044.1 - 0.042 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EMD62044.1 - 0.071 13.4 1.2 0.39 11.0 0.8 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMD62044.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Alg14 PF08660.6 EMD62044.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Endonuclease_7 PF02945.10 EMD62044.1 - 0.83 9.4 2.9 22 4.8 0.3 2.3 2 0 0 2 2 2 0 Recombination endonuclease VII MutS_V PF00488.16 EMD62046.1 - 2.3e-86 289.0 0.0 4.2e-86 288.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD62046.1 - 7.6e-37 127.0 2.0 1.7e-36 125.9 1.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMD62046.1 - 8.3e-29 99.9 0.1 1.8e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMD62046.1 - 3.1e-11 43.4 0.0 1.3e-10 41.5 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMD62046.1 - 1e-09 38.3 0.2 7.8e-09 35.5 0.2 2.5 2 0 0 2 2 2 1 MutS family domain IV Y_phosphatase3 PF13350.1 EMD62046.1 - 0.11 12.7 1.6 10 6.3 0.2 3.3 2 1 1 3 3 3 0 Tyrosine phosphatase family G_glu_transpept PF01019.16 EMD62047.1 - 2.1e-158 528.0 0.9 2.4e-158 527.8 0.6 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPR_14 PF13428.1 EMD62048.1 - 1e-13 50.5 0.1 0.078 13.6 0.0 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat Suf PF05843.9 EMD62048.1 - 4.3e-10 39.8 4.9 9.9e-05 22.2 0.1 3.7 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EMD62048.1 - 1.1e-05 25.6 0.3 0.81 10.0 0.0 3.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD62048.1 - 6.7e-05 23.4 5.7 0.00048 20.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD62048.1 - 0.053 13.4 1.6 0.72 9.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD62048.1 - 0.86 10.1 8.3 34 5.1 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 EMD62050.1 - 7.1e-84 281.6 0.1 9.4e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62050.1 - 4.4e-08 32.9 9.1 7.6e-08 32.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EMD62051.1 - 1.7e-10 40.5 0.8 2.5e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMD62051.1 - 3.6e-07 30.2 0.4 8.2e-07 29.1 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMD62051.1 - 0.091 12.5 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Apc15p PF05841.6 EMD62052.1 - 0.21 12.3 4.0 27 5.5 0.3 3.5 3 1 0 3 3 3 0 Apc15p protein tRNA-synt_1g PF09334.6 EMD62053.1 - 1.8e-115 385.7 0.0 3.6e-115 384.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMD62053.1 - 1.7e-23 82.5 1.5 6.2e-10 37.7 0.2 3.7 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EMD62053.1 - 8e-05 21.8 0.0 0.088 11.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EMD62053.1 - 0.0015 18.2 0.0 0.0061 16.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 EMD62053.1 - 0.014 14.0 0.0 0.026 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) G-patch_2 PF12656.2 EMD62054.1 - 8e-27 92.9 0.2 8e-27 92.9 0.1 5.0 6 2 0 7 7 7 1 DExH-box splicing factor binding site G-patch PF01585.18 EMD62054.1 - 3.2e-06 26.8 1.4 9.2e-06 25.3 1.0 1.9 1 0 0 1 1 1 1 G-patch domain Frag1 PF10277.4 EMD62055.1 - 1.7e-46 158.3 24.4 2e-46 158.1 16.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 EMD62055.1 - 0.00081 18.7 4.4 0.00081 18.7 3.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF998) SdpI PF13630.1 EMD62055.1 - 0.018 14.7 2.1 0.018 14.7 1.4 3.2 3 0 0 3 3 3 0 SdpI/YhfL protein family Orn_Arg_deC_N PF02784.11 EMD62057.1 - 1.9e-79 266.4 0.0 2.7e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMD62057.1 - 9.8e-31 105.8 0.1 1.6e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IGR PF09597.5 EMD62058.1 - 3.5e-24 84.4 0.0 1.3e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 IGR protein motif WD40 PF00400.27 EMD62059.1 - 6.9e-24 82.8 9.5 5e-08 32.5 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 EMD62059.1 - 0.027 13.6 0.3 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Cortical protein marker for cell polarity E3_binding PF02817.12 EMD62059.1 - 0.063 12.9 0.1 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 e3 binding domain Zn_clus PF00172.13 EMD62060.1 - 8.8e-05 22.3 8.2 0.00017 21.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD62060.1 - 0.011 14.5 0.5 0.067 12.0 0.1 2.0 1 1 0 2 2 2 0 Fungal specific transcription factor domain BAF1_ABF1 PF04684.8 EMD62061.1 - 3.7 6.2 6.2 4.8 5.9 4.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zn_clus PF00172.13 EMD62062.1 - 0.0017 18.2 10.0 0.0031 17.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-LYAR PF08790.6 EMD62063.1 - 3.6e-14 52.1 3.7 3.6e-14 52.1 2.6 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger IncA PF04156.9 EMD62063.1 - 0.41 10.2 4.6 1.1 8.8 3.2 1.7 1 0 0 1 1 1 0 IncA protein Evr1_Alr PF04777.8 EMD62064.1 - 2.1e-28 98.0 0.1 2.7e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EMD62064.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Aminotran_4 PF01063.14 EMD62065.1 - 6.6e-21 74.8 0.0 8.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Peptidase_C48 PF02902.14 EMD62066.1 - 1.3e-16 60.8 0.0 1.1e-15 57.8 0.0 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_47 PF01532.15 EMD62067.1 - 2.3e-164 547.3 0.2 3e-164 546.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_L38e PF01781.13 EMD62068.1 - 2.5e-31 107.2 2.3 2.9e-31 107.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.6 EMD62068.1 - 0.065 12.9 0.2 2.1 8.1 0.1 2.2 1 1 1 2 2 2 0 Poxvirus A3L Protein SAM_PNT PF02198.11 EMD62069.1 - 0.12 12.0 1.3 0.18 11.6 0.9 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ATG16 PF08614.6 EMD62070.1 - 0.001 18.9 3.5 0.001 18.9 2.4 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EMD62070.1 - 1.6 8.2 4.4 3.2 7.3 3.1 1.4 1 0 0 1 1 1 0 IncA protein Iso_dh PF00180.15 EMD62071.1 - 5.5e-84 282.0 0.0 6.8e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EMD62072.1 - 8e-16 58.3 6.3 1.5e-15 57.4 4.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EMD62072.1 - 2.8e-10 40.5 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD62072.1 - 1e-06 29.0 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62072.1 - 1.7e-06 27.7 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD62072.1 - 4.5e-05 23.2 0.0 6.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD62072.1 - 6.1e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62072.1 - 0.00025 21.6 0.0 0.00062 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD62072.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMD62072.1 - 0.0036 16.8 0.0 0.0097 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMD62072.1 - 0.0066 15.5 0.0 0.67 8.9 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 EMD62073.1 - 8.1e-90 299.8 0.0 9.3e-90 299.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 NatB_MDM20 PF09797.4 EMD62074.1 - 6.3e-14 51.4 0.0 2.5e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit FlxA PF14282.1 EMD62075.1 - 0.022 14.7 1.6 0.022 14.7 1.1 1.6 2 0 0 2 2 2 0 FlxA-like protein OGFr_III PF04680.8 EMD62075.1 - 0.028 14.5 1.0 0.077 13.1 0.7 1.8 1 0 0 1 1 1 0 Opioid growth factor receptor repeat Nuc_deoxyrib_tr PF05014.10 EMD62075.1 - 0.033 14.0 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF4355 PF14265.1 EMD62075.1 - 4.3 7.3 10.0 15 5.5 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) AIG2_2 PF13772.1 EMD62078.1 - 8.5e-06 25.7 0.1 2.9e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 AIG2-like family Glyco_hydro_16 PF00722.16 EMD62079.1 - 1.3e-08 34.3 0.7 8.3e-08 31.7 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.17 EMD62079.1 - 4.4e-06 25.7 32.6 8.7e-06 24.7 22.6 1.4 1 0 0 1 1 1 1 Acyltransferase family Glyco_tranf_2_3 PF13641.1 EMD62080.1 - 1.1e-28 100.6 0.0 1.5e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD62080.1 - 4.2e-25 88.5 6.7 4.2e-25 88.5 4.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMD62080.1 - 6e-10 38.6 0.0 8.8e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD62080.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Acyl_transf_3 PF01757.17 EMD62081.1 - 1.6 7.5 37.8 5.8 5.6 26.2 2.3 1 1 0 1 1 1 0 Acyltransferase family MFS_1 PF07690.11 EMD62082.1 - 2.3e-26 92.3 39.5 3.9e-26 91.5 27.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 EMD62083.1 - 5.3e-15 55.2 0.2 1.2e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.23 EMD62084.1 - 2e-66 224.1 0.0 3.3e-66 223.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD62084.1 - 8.5e-08 33.0 0.0 2.8e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TUG-UBL1 PF11470.3 EMD62085.1 - 4.7e-26 90.4 0.5 1.9e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EMD62085.1 - 1.2e-11 44.4 0.0 1.1e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 UBX domain ubiquitin PF00240.18 EMD62085.1 - 0.008 15.5 0.0 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family PITH PF06201.8 EMD62086.1 - 2.1e-45 154.2 0.5 2.3e-44 150.8 0.0 2.2 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.15 EMD62086.1 - 5.1e-15 55.0 0.0 1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMD62086.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EMD62086.1 - 0.01 15.6 0.1 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMD62086.1 - 0.015 15.4 0.2 1.9 8.6 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Serglycin PF04360.7 EMD62086.1 - 3.2 7.4 5.9 5.2 6.7 3.8 1.4 1 1 0 1 1 1 0 Serglycin Ribosomal_L36e PF01158.13 EMD62087.1 - 4.7e-39 132.3 4.8 5.4e-39 132.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2207 PF09972.4 EMD62087.1 - 0.12 10.8 0.1 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MRP-L28 PF09812.4 EMD62087.1 - 0.16 11.8 1.0 0.19 11.5 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Ribosomal_L41 PF05162.8 EMD62087.1 - 0.79 9.4 7.1 3 7.5 4.9 2.1 1 1 0 1 1 1 0 Ribosomal protein L41 AMP-binding PF00501.23 EMD62088.1 - 1.6e-95 319.9 0.0 2e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD62088.1 - 4.7e-12 46.6 0.0 2.3e-11 44.4 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 4HBT_3 PF13622.1 EMD62089.1 - 4e-51 174.2 0.0 4.6e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EMD62089.1 - 0.00028 20.9 0.1 0.56 10.3 0.0 2.2 2 0 0 2 2 2 2 Thioesterase superfamily EXS PF03124.9 EMD62091.1 - 1.4e-105 353.1 3.0 1.6e-105 352.9 2.1 1.0 1 0 0 1 1 1 1 EXS family TetR_N PF00440.18 EMD62092.1 - 0.082 12.5 0.6 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.7 EMD62092.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 N-SET PF11764.3 EMD62093.1 - 2.9e-48 163.9 5.6 2.9e-48 163.9 3.9 3.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EMD62093.1 - 6.5e-25 86.2 0.9 1.4e-24 85.1 0.6 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EMD62093.1 - 4.4e-24 85.6 0.1 4.4e-24 85.6 0.1 3.5 3 2 0 3 3 3 1 SET domain RRM_6 PF14259.1 EMD62093.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD62093.1 - 0.0008 18.9 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 EMD62094.1 - 1.7e-44 150.9 0.0 1.1e-23 83.5 0.0 2.0 1 1 1 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.17 EMD62095.1 - 8.7e-54 180.6 0.0 3.6e-29 101.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EMD62095.1 - 3.1e-27 95.2 0.0 1.1e-17 63.8 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMD62095.1 - 3.7e-19 69.0 0.0 8.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMD62095.1 - 1.3e-11 44.2 0.0 2.8e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMD62095.1 - 1.1e-06 27.5 0.0 2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EMD62095.1 - 0.0042 16.8 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 SIS domain PG_binding_1 PF01471.13 EMD62095.1 - 0.15 12.0 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Aa_trans PF01490.13 EMD62097.1 - 4e-83 279.1 32.0 4.8e-83 278.9 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EMD62098.1 - 1.8e-63 214.5 32.5 2.3e-63 214.2 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD62098.1 - 9.3e-19 67.2 38.2 1.3e-18 66.7 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 EMD62099.1 - 4.1e-14 51.8 0.0 0.0031 17.3 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF484 PF04340.7 EMD62099.1 - 0.11 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 HSA PF07529.8 EMD62100.1 - 6e-17 61.2 2.7 6e-17 61.2 1.9 3.7 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EMD62100.1 - 3e-12 46.4 0.4 3e-12 46.4 0.3 3.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMD62100.1 - 0.00037 20.4 0.4 0.0013 18.7 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_L_2 PF13656.1 EMD62101.1 - 7.9e-24 82.8 0.0 1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMD62101.1 - 5.8e-11 41.3 0.0 7.9e-11 40.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Methuselah_N PF06652.7 EMD62101.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methuselah N-terminus R3H PF01424.17 EMD62102.1 - 6.1e-14 51.4 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EMD62102.1 - 2.9e-05 23.9 37.4 0.00024 20.9 10.5 11.8 12 2 0 12 12 12 6 NF-X1 type zinc finger ATP-synt_S1 PF05827.7 EMD62103.1 - 7.9e-34 117.2 0.0 1.4e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TMEM18 PF14770.1 EMD62103.1 - 0.085 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 18 KaiC PF06745.8 EMD62103.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 KaiC FAD_binding_3 PF01494.14 EMD62104.1 - 5.9e-14 51.8 0.0 9.5e-14 51.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD62104.1 - 1.4e-07 30.7 0.1 0.0003 19.8 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62104.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD62104.1 - 0.0035 17.7 0.2 3.1 8.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD62104.1 - 0.0041 16.8 0.0 0.47 10.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMD62104.1 - 0.062 11.9 0.3 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMD62104.1 - 0.067 13.0 0.2 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD62104.1 - 0.11 11.3 0.3 0.19 10.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_10 PF00331.15 EMD62106.1 - 2.5e-96 322.4 1.9 2.9e-96 322.2 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 p450 PF00067.17 EMD62107.1 - 2.9e-53 181.0 0.0 4.7e-53 180.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.1 EMD62108.1 - 1.6e-23 83.0 0.0 2.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EMD62108.1 - 4.6e-06 27.1 0.1 8.3e-06 26.3 0.0 1.4 2 0 0 2 2 2 1 Putative lumazine-binding DUF4440 PF14534.1 EMD62108.1 - 0.0009 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EMD62108.1 - 0.0017 18.7 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.3 EMD62108.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) Scytalone_dh PF02982.9 EMD62108.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Scytalone dehydratase SnoaL PF07366.7 EMD62108.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase NTF2 PF02136.15 EMD62108.1 - 0.047 14.0 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain TPR_12 PF13424.1 EMD62110.1 - 7.2e-79 259.7 13.4 8.4e-16 57.6 0.0 5.8 2 1 5 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EMD62110.1 - 3.3e-77 252.4 8.4 3e-13 49.1 0.0 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat HET PF06985.6 EMD62110.1 - 3.6e-21 75.7 9.5 5.5e-19 68.7 6.6 3.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.1 EMD62110.1 - 4.1e-17 60.5 13.7 0.023 14.4 0.0 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat NB-ARC PF00931.17 EMD62110.1 - 1.4e-14 53.6 0.0 3e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EMD62110.1 - 1.9e-13 49.4 8.1 0.25 11.6 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 EMD62110.1 - 1.7e-11 43.3 0.3 0.66 10.5 0.0 7.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD62110.1 - 6.8e-11 42.5 0.2 0.016 15.8 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD62110.1 - 7.6e-11 41.0 11.2 0.43 10.6 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD62110.1 - 1.6e-09 36.9 8.0 0.49 10.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD62110.1 - 1.9e-09 37.5 6.5 0.017 15.2 0.0 6.1 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EMD62110.1 - 4.9e-09 36.4 0.1 2.3e-08 34.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 EMD62110.1 - 1.9e-08 33.7 4.3 0.33 10.6 0.0 5.7 3 1 1 5 5 5 3 TPR repeat AAA_16 PF13191.1 EMD62110.1 - 6.3e-07 29.5 3.3 1.2e-06 28.6 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain TPR_19 PF14559.1 EMD62110.1 - 9.1e-06 25.9 4.2 4.2 7.7 0.0 6.3 1 1 6 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD62110.1 - 0.00062 19.3 5.9 16 5.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_25 PF13481.1 EMD62110.1 - 0.0011 18.3 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMD62110.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase TPR_6 PF13174.1 EMD62110.1 - 0.012 16.0 10.7 23 5.7 0.1 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMD62110.1 - 0.012 15.3 0.6 9.6 6.1 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA PF00004.24 EMD62110.1 - 0.023 14.9 0.0 0.088 13.0 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMD62110.1 - 0.026 13.9 0.0 0.074 12.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein PPR PF01535.15 EMD62110.1 - 0.043 13.8 2.8 19 5.5 0.0 5.4 6 0 0 6 6 5 0 PPR repeat PhoH PF02562.11 EMD62110.1 - 0.06 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EMD62110.1 - 0.07 12.5 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EMD62110.1 - 0.083 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein TPR_14 PF13428.1 EMD62110.1 - 3.2 8.6 13.1 71 4.4 0.0 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat Thioredoxin_7 PF13899.1 EMD62111.1 - 7.8e-15 54.6 0.1 3e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.1 EMD62111.1 - 7.4e-14 51.0 0.0 2e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EMD62111.1 - 1.5e-08 34.5 0.0 4.5e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.1 EMD62111.1 - 0.0024 18.0 0.1 0.0071 16.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EMD62111.1 - 0.063 12.9 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Ecm29 PF13001.2 EMD62112.1 - 1.8e-150 501.7 0.2 3.9e-150 500.6 0.1 1.6 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EMD62112.1 - 8.6e-08 31.6 10.1 0.26 11.4 0.0 7.8 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EMD62112.1 - 4.6e-06 26.9 0.6 0.014 15.7 0.1 5.1 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EMD62112.1 - 0.0012 18.4 0.1 2.7 7.6 0.0 3.9 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 EMD62112.1 - 0.0017 18.7 10.4 35 5.0 0.1 8.0 7 1 2 9 9 9 0 HEAT-like repeat Ldh_1_N PF00056.18 EMD62113.1 - 2.6e-35 121.2 0.0 4.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMD62113.1 - 1.6e-28 99.5 0.0 2.3e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TrkA_N PF02254.13 EMD62113.1 - 0.00058 19.8 0.1 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EMD62113.1 - 0.0025 18.2 0.1 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EMD62113.1 - 0.0035 16.7 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EMD62113.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family OCD_Mu_crystall PF02423.10 EMD62113.1 - 0.076 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Pkinase PF00069.20 EMD62114.1 - 5.2e-19 68.4 0.0 7.2e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62114.1 - 1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD62114.1 - 0.00087 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3189 PF11385.3 EMD62115.1 - 0.04 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Tetraspannin PF00335.15 EMD62119.1 - 0.0016 17.7 6.8 0.0016 17.7 4.7 1.6 1 1 1 2 2 2 1 Tetraspanin family MARVEL PF01284.18 EMD62119.1 - 0.0066 16.2 10.7 0.0066 16.2 7.4 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 EMD62119.1 - 0.033 13.7 3.7 0.048 13.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF202 PF02656.10 EMD62119.1 - 0.064 13.4 6.7 2 8.6 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Ninjurin PF04923.7 EMD62119.1 - 0.082 12.6 1.1 3 7.6 0.0 2.5 1 1 0 2 2 2 0 Ninjurin OATP PF03137.15 EMD62119.1 - 0.15 10.0 4.9 0.15 10.0 0.1 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3329 PF11808.3 EMD62119.1 - 0.22 11.6 1.1 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) 7TMR-DISM_7TM PF07695.6 EMD62119.1 - 2.2 7.9 11.0 0.17 11.5 4.0 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling Claudin_2 PF13903.1 EMD62119.1 - 2.6 7.7 9.8 21 4.7 6.8 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Vpu PF00558.14 EMD62119.1 - 2.9 7.5 9.0 8.7 5.9 1.0 2.9 2 1 1 3 3 3 0 Vpu protein HET PF06985.6 EMD62120.1 - 9.4e-25 87.3 0.0 1.3e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF912 PF06024.7 EMD62121.1 - 0.072 13.1 0.7 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_M19 PF01244.16 EMD62122.1 - 2.1e-102 342.3 0.0 2.4e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EMD62122.1 - 0.052 13.0 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Ilm1 PF10311.4 EMD62123.1 - 5.9e-46 155.9 0.2 6.7e-46 155.8 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 TadE PF07811.7 EMD62123.1 - 6.1 6.8 6.5 4.8 7.1 0.1 3.1 3 0 0 3 3 3 0 TadE-like protein MOSC_N PF03476.11 EMD62124.1 - 9.8e-24 83.3 0.0 1.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 EMD62124.1 - 2e-23 82.7 0.0 6.3e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 EMD62124.1 - 1e-22 80.0 0.0 2.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain DUF1388 PF07142.7 EMD62126.1 - 0.21 11.3 5.3 7.9 6.2 0.1 4.2 4 0 0 4 4 4 0 Repeat of unknown function (DUF1388) TFIIF_alpha PF05793.7 EMD62126.1 - 1 7.6 6.0 1.2 7.4 4.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4614 PF15391.1 EMD62126.1 - 8.7 6.0 14.5 8.1 6.1 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) HIRA_B PF09453.5 EMD62127.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 HIRA B motif RRM_6 PF14259.1 EMD62128.1 - 0.00012 21.9 0.0 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SHR3_chaperone PF08229.6 EMD62129.1 - 5e-69 231.2 0.1 6.4e-69 230.8 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 MCM PF00493.18 EMD62130.1 - 8.2e-131 435.7 0.0 1.3e-130 435.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMD62130.1 - 5.2e-29 101.1 0.2 1.5e-28 99.7 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMD62130.1 - 3.3e-07 29.6 0.0 2.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMD62130.1 - 5.7e-06 26.0 0.0 1.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMD62130.1 - 0.033 13.7 0.1 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EMD62130.1 - 0.044 14.1 0.4 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMD62130.1 - 0.092 12.2 0.0 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 EMD62130.1 - 0.24 11.3 1.9 0.7 9.8 1.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain AAA PF00004.24 EMD62131.1 - 1.8e-53 180.2 0.0 1.9e-43 147.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EMD62131.1 - 2.3e-28 98.0 0.8 2.3e-28 98.0 0.6 2.0 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EMD62131.1 - 2.3e-09 37.4 2.6 0.0013 18.7 0.0 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EMD62131.1 - 6.1e-07 29.5 0.0 0.046 13.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EMD62131.1 - 1e-05 25.5 0.0 0.0028 17.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EMD62131.1 - 2.3e-05 24.5 1.6 0.27 11.3 0.0 3.9 3 2 0 3 3 2 2 AAA domain NACHT PF05729.7 EMD62131.1 - 5.4e-05 22.9 0.7 0.18 11.4 0.0 3.8 3 1 0 3 3 3 1 NACHT domain AAA_5 PF07728.9 EMD62131.1 - 0.00012 21.7 0.1 0.64 9.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMD62131.1 - 0.00024 20.2 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EMD62131.1 - 0.00026 21.8 0.0 0.12 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD62131.1 - 0.0003 19.8 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMD62131.1 - 0.00031 20.2 0.2 0.59 9.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 EMD62131.1 - 0.00049 19.9 0.1 0.33 10.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EMD62131.1 - 0.001 18.7 2.0 2.3 8.0 0.0 3.6 4 0 0 4 4 4 2 Part of AAA domain AAA_25 PF13481.1 EMD62131.1 - 0.0012 18.2 5.7 2 7.7 0.1 4.4 3 2 1 5 5 5 1 AAA domain AAA_14 PF13173.1 EMD62131.1 - 0.0017 18.2 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD62131.1 - 0.0039 17.5 0.1 3 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMD62131.1 - 0.0047 16.4 0.0 0.69 9.3 0.0 3.2 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EMD62131.1 - 0.007 16.5 0.0 4.4 7.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 EMD62131.1 - 0.014 14.9 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EMD62131.1 - 0.033 14.4 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 ABC transporter SKI PF01202.17 EMD62131.1 - 0.034 14.0 0.0 4.9 6.9 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase Mg_chelatase PF01078.16 EMD62131.1 - 0.037 13.1 0.2 0.68 9.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMD62131.1 - 0.038 13.9 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EMD62131.1 - 0.09 12.6 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family TIP49 PF06068.8 EMD62131.1 - 0.16 10.6 0.0 0.91 8.1 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus Peptidase_S66 PF02016.10 EMD62131.1 - 0.19 10.6 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase DUF918 PF06033.6 EMD62131.1 - 0.28 10.7 0.0 0.59 9.6 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) MPC PF03650.8 EMD62132.1 - 2.7e-34 117.6 0.1 3.1e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EMD62133.1 - 7.1e-18 63.9 0.1 9.8e-18 63.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EMD62134.1 - 1.3e-23 82.5 0.0 1.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMD62134.1 - 2.7e-21 75.0 0.1 7.3e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 ketoacyl-synt PF00109.21 EMD62135.1 - 1.2e-65 221.4 0.0 4.1e-65 219.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMD62135.1 - 3.1e-58 196.4 0.0 7e-58 195.2 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EMD62135.1 - 6.6e-56 189.9 0.0 4.1e-55 187.3 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMD62135.1 - 1.9e-54 184.8 0.1 3.9e-54 183.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMD62135.1 - 6e-46 156.4 0.0 2.3e-45 154.5 0.0 2.1 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD62135.1 - 8e-39 132.1 0.1 1.9e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD62135.1 - 2.3e-19 69.2 0.0 1.2e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMD62135.1 - 5.2e-19 68.5 0.0 1.3e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD62135.1 - 2e-17 63.3 0.0 4.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62135.1 - 8.9e-12 45.3 0.0 2.8e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62135.1 - 2.6e-10 40.0 0.0 6.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62135.1 - 4e-09 37.0 0.0 1.9e-08 34.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD62135.1 - 2.6e-08 34.8 0.0 1.3e-06 29.3 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD62135.1 - 3.1e-08 33.3 0.4 7.8e-08 32.0 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EMD62135.1 - 3.1e-07 30.6 0.0 8.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMD62135.1 - 3.5e-06 27.1 0.8 1.3e-05 25.3 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EMD62135.1 - 8.7e-06 25.0 0.0 2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EMD62135.1 - 0.00037 19.5 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 EMD62135.1 - 0.00089 18.7 0.0 0.0047 16.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 EMD62135.1 - 0.0022 18.0 0.0 0.0069 16.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMD62135.1 - 0.0028 17.1 0.1 0.014 14.8 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase Dmrt1 PF12374.3 EMD62135.1 - 0.026 14.8 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 DREV PF05219.7 EMD62135.1 - 0.037 12.9 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 EMD62135.1 - 0.053 12.8 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) p450 PF00067.17 EMD62136.1 - 2.2e-22 79.2 0.1 3.4e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Alpha-amylase PF00128.19 EMD62138.1 - 1.4e-82 277.6 0.0 2.1e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Aminotran_5 PF00266.14 EMD62138.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FSH1 PF03959.8 EMD62139.1 - 6.9e-09 35.4 0.0 8.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Fasciclin PF02469.17 EMD62141.1 - 2e-20 73.0 0.0 4.8e-15 55.7 0.0 3.0 2 1 0 2 2 2 2 Fasciclin domain Aminotran_3 PF00202.16 EMD62142.1 - 3.9e-36 124.5 0.2 5.7e-16 58.2 0.0 3.1 2 1 1 3 3 3 3 Aminotransferase class-III ADH_N PF08240.7 EMD62143.1 - 3.6e-27 94.2 4.1 3.6e-27 94.2 2.9 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD62143.1 - 6.3e-10 38.7 0.0 3.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMD62143.1 - 7.8e-08 31.8 0.3 1.4e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Apc1 PF12859.2 EMD62145.1 - 0.12 12.6 0.2 0.37 11.0 0.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 PALP PF00291.20 EMD62146.1 - 6.7e-65 219.3 0.3 9.4e-65 218.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.17 EMD62147.1 - 3.1e-47 156.0 9.6 3.6e-10 38.7 0.1 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 EMD62147.1 - 0.49 9.8 7.0 4.5 6.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) zf-C3HC4 PF00097.20 EMD62149.1 - 1.6e-09 37.2 8.5 2.8e-09 36.4 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD62149.1 - 5.2e-09 35.6 5.0 8.2e-09 35.0 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD62149.1 - 1.2e-08 34.8 8.2 1.9e-08 34.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 EMD62149.1 - 1.1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EMD62149.1 - 3.8e-07 29.8 7.0 5.8e-07 29.2 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD62149.1 - 3.4e-06 26.6 6.6 5.6e-06 25.9 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.9 EMD62149.1 - 0.00021 20.7 5.6 0.00056 19.3 3.8 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.2 EMD62149.1 - 0.00051 20.0 1.7 0.00085 19.3 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EMD62149.1 - 0.00075 19.0 5.0 0.0016 17.9 3.5 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMD62149.1 - 0.00098 18.9 7.1 0.0018 18.0 4.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMD62149.1 - 0.019 14.6 3.2 0.058 13.1 2.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 EMD62149.1 - 0.03 13.7 0.1 0.078 12.4 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif PDDEXK_4 PF14281.1 EMD62149.1 - 0.03 14.1 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily zf-RING_6 PF14835.1 EMD62149.1 - 0.033 13.9 2.1 0.057 13.1 1.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IceA2 PF05862.6 EMD62149.1 - 0.061 13.0 0.3 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 Helicobacter pylori IceA2 protein C1_4 PF07975.7 EMD62149.1 - 0.063 13.2 0.8 0.13 12.3 0.6 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain DUF1272 PF06906.6 EMD62149.1 - 0.083 12.7 2.5 0.15 11.9 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2 PF00096.21 EMD62151.1 - 4.1e-11 42.5 19.7 3.9e-07 30.0 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD62151.1 - 1.6e-10 40.5 11.3 0.00011 22.3 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD62151.1 - 4e-06 26.7 6.7 0.0034 17.4 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EMD62151.1 - 1.9e-05 24.6 15.3 0.00026 21.1 4.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMD62151.1 - 0.00026 20.7 0.9 0.00026 20.7 0.6 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EMD62151.1 - 0.00047 20.2 9.5 0.0031 17.6 0.3 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type LIM PF00412.17 EMD62151.1 - 0.39 10.8 3.8 0.94 9.6 2.7 1.7 1 0 0 1 1 1 0 LIM domain Zn-ribbon_8 PF09723.5 EMD62151.1 - 4.4 7.3 5.7 5.9 6.9 0.4 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.6 EMD62151.1 - 5.2 6.8 8.1 4 7.2 0.5 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger ATP_bind_4 PF01902.12 EMD62152.1 - 1.5e-21 76.8 0.0 2.9e-14 52.9 0.0 2.3 1 1 1 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EMD62152.1 - 5.4e-14 51.9 0.0 1.8e-06 27.7 0.0 4.2 3 1 1 4 4 4 3 Endoribonuclease L-PSP MDM31_MDM32 PF08118.6 EMD62153.1 - 1.5e-189 630.6 1.1 1.7e-189 630.4 0.8 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EMD62154.1 - 4.4e-05 23.0 1.3 8.3e-05 22.1 0.9 1.4 1 0 0 1 1 1 1 KH domain ABC2_membrane PF01061.19 EMD62155.1 - 2.8e-88 294.5 62.4 2.3e-47 160.8 10.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMD62155.1 - 1.7e-37 128.8 0.1 1.5e-18 67.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD62155.1 - 2.1e-32 110.8 1.2 6.5e-27 93.2 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMD62155.1 - 3.3e-08 33.5 0.1 9.5e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EMD62155.1 - 3.7e-06 26.2 0.1 0.00018 20.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EMD62155.1 - 5.4e-06 26.5 3.2 0.021 14.8 2.2 3.4 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMD62155.1 - 9.3e-06 25.2 0.1 0.094 12.1 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMD62155.1 - 3.1e-05 23.9 0.0 0.0064 16.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EMD62155.1 - 4.4e-05 22.9 0.5 0.023 14.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EMD62155.1 - 6.4e-05 22.4 0.0 0.018 14.4 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EMD62155.1 - 6.5e-05 22.4 0.1 0.091 12.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EMD62155.1 - 0.00014 21.9 0.0 0.31 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EMD62155.1 - 0.00015 20.9 41.1 0.0036 16.3 7.1 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EMD62155.1 - 0.00021 21.1 0.0 0.036 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD62155.1 - 0.00024 21.1 6.1 0.00079 19.4 0.1 3.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 EMD62155.1 - 0.00055 20.2 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD62155.1 - 0.0008 20.2 0.0 0.036 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMD62155.1 - 0.0014 18.1 0.1 0.51 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 EMD62155.1 - 0.0014 18.5 0.1 0.0041 17.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.14 EMD62155.1 - 0.0027 16.9 1.7 0.056 12.6 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EMD62155.1 - 0.0046 15.8 0.6 4.7 5.9 0.1 3.1 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.7 EMD62155.1 - 0.014 15.0 0.1 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EMD62155.1 - 0.017 14.9 0.3 0.062 13.1 0.2 2.0 1 0 0 1 1 1 0 Dynamin family Septin PF00735.13 EMD62155.1 - 0.039 12.9 0.1 0.18 10.7 0.1 1.9 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.7 EMD62155.1 - 0.054 12.5 0.1 0.14 11.2 0.1 1.6 2 0 0 2 2 1 0 Zeta toxin UPF0079 PF02367.12 EMD62155.1 - 0.066 12.8 0.5 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GBP PF02263.14 EMD62155.1 - 0.072 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain ArgK PF03308.11 EMD62155.1 - 0.099 11.4 2.3 0.61 8.8 0.1 3.0 4 0 0 4 4 3 0 ArgK protein T2SE PF00437.15 EMD62155.1 - 0.14 11.0 0.1 5.6 5.7 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EMD62155.1 - 0.27 10.2 0.0 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NAD_Gly3P_dh_N PF01210.18 EMD62156.1 - 2.2e-46 157.4 0.0 5.9e-46 156.0 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMD62156.1 - 7.9e-46 155.4 0.1 1.2e-45 154.9 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus RAP1 PF07218.6 EMD62157.1 - 9.6 4.1 8.8 9.4 4.1 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_4 PF07993.7 EMD62158.1 - 1.4e-46 158.4 0.0 2.2e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMD62158.1 - 6.2e-26 90.7 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMD62158.1 - 6.4e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMD62158.1 - 5.8e-09 36.0 0.0 1.5e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMD62158.1 - 2e-05 23.4 0.0 0.00047 18.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMD62158.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EMD62158.1 - 0.02 14.8 1.3 0.31 10.9 0.9 2.5 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EMD62158.1 - 0.029 14.0 0.6 0.32 10.6 0.4 2.4 1 1 0 1 1 1 0 KR domain GH3 PF03321.8 EMD62158.1 - 0.039 12.4 0.0 0.063 11.7 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PCDO_beta_N PF12391.3 EMD62159.1 - 0.053 12.9 0.9 0.14 11.6 0.6 1.8 1 1 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal MFS_1 PF07690.11 EMD62160.1 - 1.7e-38 132.2 47.8 1.7e-38 132.2 33.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62160.1 - 0.00026 19.6 15.8 0.00026 19.6 10.9 3.4 2 2 2 4 4 4 2 Sugar (and other) transporter C2 PF00168.25 EMD62161.1 - 7.3e-09 35.3 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.11 EMD62162.1 - 6.5e-47 159.9 38.8 6.5e-47 159.9 26.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62162.1 - 1.1e-08 34.0 13.6 1.1e-08 34.0 9.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EMD62162.1 - 0.47 8.4 12.1 0.29 9.1 1.8 3.4 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.16 EMD62163.1 - 7.2e-23 81.2 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD62163.1 - 8.2e-11 41.1 0.0 1.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMD62163.1 - 2.4e-10 39.7 0.0 3.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMD62163.1 - 7.8e-07 29.2 0.0 6.8e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD62163.1 - 1e-06 27.8 0.1 7.7e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMD62163.1 - 4.1e-05 22.6 0.0 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KIF1B PF12423.3 EMD62163.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Kinesin protein 1B Proteasome PF00227.21 EMD62164.1 - 3.6e-27 94.8 0.0 4.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EMD62165.1 - 1.5e-26 92.2 0.8 2.2e-26 91.7 0.6 1.3 1 0 0 1 1 1 1 HCNGP-like protein Hepatitis_core PF00906.15 EMD62165.1 - 4.9 6.7 6.5 7.8 6.1 4.5 1.3 1 0 0 1 1 1 0 Hepatitis core antigen FAD_binding_2 PF00890.19 EMD62166.1 - 2.1e-27 96.0 0.0 2.6e-25 89.1 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EMD62166.1 - 1.8e-08 33.9 0.0 2.3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMD62166.1 - 7e-05 22.0 0.2 0.00025 20.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMD62166.1 - 0.0029 17.5 0.0 0.0072 16.2 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD62166.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD62166.1 - 0.032 13.1 0.1 0.068 12.0 0.0 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD62166.1 - 0.047 12.1 0.0 0.065 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Proteasome PF00227.21 EMD62167.1 - 2.5e-31 108.4 0.1 6.8e-31 107.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Enolase_C PF00113.17 EMD62168.1 - 7.3e-153 507.7 0.1 1e-152 507.3 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMD62168.1 - 9.2e-58 193.8 0.9 1.7e-57 193.0 0.6 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EMD62168.1 - 0.011 14.6 1.0 0.35 9.7 0.1 2.8 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EMD62168.1 - 0.014 15.3 0.2 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 EMD62168.1 - 0.018 15.5 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF3356 PF11836.3 EMD62168.1 - 0.04 13.7 0.1 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) Proteasome PF00227.21 EMD62169.1 - 1.1e-36 125.9 0.0 1.2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DHQ_synthase PF01761.15 EMD62170.1 - 4.5e-55 186.3 0.0 6.5e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EMD62170.1 - 3.2e-10 39.7 0.0 5.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 EMD62171.1 - 1.4e-14 53.6 0.0 1.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMD62171.1 - 1.8e-09 38.3 0.0 2.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EMD62171.1 - 0.00088 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 EMD62171.1 - 0.033 14.7 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_4 PF13535.1 EMD62172.1 - 8.4e-09 35.4 0.0 2.3e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD62172.1 - 0.00011 21.1 0.0 0.00045 19.0 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GTSE1_N PF15259.1 EMD62173.1 - 0.0026 17.7 0.1 0.007 16.3 0.0 1.8 2 0 0 2 2 2 1 G-2 and S-phase expressed 1 MutS_IV PF05190.13 EMD62173.1 - 0.15 12.2 0.1 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 MutS family domain IV Kinesin PF00225.18 EMD62175.1 - 9.3e-95 317.1 0.0 2.3e-94 315.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF2031 PF09592.5 EMD62175.1 - 0.013 14.6 4.7 0.026 13.6 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Trep_dent_lipo PF09710.5 EMD62175.1 - 0.014 14.0 2.6 0.023 13.3 1.8 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) CdhD PF03599.11 EMD62176.1 - 0.045 12.2 0.0 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit WD40 PF00400.27 EMD62178.1 - 2.3e-79 258.6 18.6 9.5e-10 37.9 0.1 12.3 12 1 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 EMD62178.1 - 2.4e-42 143.9 0.0 3.8e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 EMD62178.1 - 2.5e-05 23.1 3.2 0.68 8.6 0.0 5.8 3 2 2 6 6 6 2 Nup133 N terminal like Nup160 PF11715.3 EMD62178.1 - 0.00011 20.5 0.8 0.29 9.2 0.0 4.5 3 2 1 4 4 4 2 Nucleoporin Nup120/160 UCH PF00443.24 EMD62179.1 - 1.7e-28 99.5 0.0 2.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMD62179.1 - 6.2e-11 42.2 0.2 1.4e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMD62179.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cpn60_TCP1 PF00118.19 EMD62180.1 - 8.7e-134 446.7 10.6 1e-133 446.5 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EMD62180.1 - 0.31 11.2 2.0 1.8 8.7 0.0 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Ribonuc_2-5A PF06479.7 EMD62181.1 - 9.2e-44 148.4 0.1 1.5e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EMD62181.1 - 1.6e-43 148.7 0.0 2.4e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62181.1 - 7.2e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EMD62181.1 - 0.0022 17.4 0.1 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat Polyketide_cyc PF03364.15 EMD62182.1 - 6.1e-17 61.8 0.1 1.7e-16 60.4 0.1 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMD62182.1 - 4.2e-05 23.7 1.4 0.00012 22.2 1.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.7 EMD62183.1 - 1.2e-13 51.3 0.0 3.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD62183.1 - 1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62183.1 - 8e-10 39.0 0.0 1.9e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62183.1 - 5.3e-09 36.6 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD62183.1 - 6.6e-09 36.0 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62183.1 - 2.2e-06 27.3 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD62183.1 - 2.9e-05 24.0 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EMD62183.1 - 5.4e-05 23.9 0.0 0.00012 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD62183.1 - 0.00039 19.6 0.0 0.00086 18.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 EMD62183.1 - 0.0068 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.12 EMD62183.1 - 0.01 14.8 0.0 0.47 9.3 0.0 2.5 2 1 0 2 2 2 0 NNMT/PNMT/TEMT family MTS PF05175.9 EMD62183.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_16 PF13191.1 EMD62184.1 - 9.6e-12 45.2 1.0 4.7e-10 39.7 0.0 3.2 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMD62184.1 - 2.6e-11 43.7 0.1 1.8e-10 41.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EMD62184.1 - 3.9e-10 40.0 0.0 1.2e-09 38.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EMD62184.1 - 5.7e-06 25.9 0.0 1.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal Arch_ATPase PF01637.13 EMD62184.1 - 0.0037 16.9 0.1 0.018 14.7 0.0 2.2 2 2 1 3 3 3 1 Archaeal ATPase NTPase_1 PF03266.10 EMD62184.1 - 0.0038 16.9 0.1 0.072 12.7 0.0 2.2 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.1 EMD62184.1 - 0.0039 17.0 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD62184.1 - 0.0048 17.0 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EMD62184.1 - 0.0066 17.2 0.0 0.022 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMD62184.1 - 0.0068 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Miro PF08477.8 EMD62184.1 - 0.011 16.2 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EMD62184.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA12 PF10443.4 EMD62184.1 - 0.037 12.5 0.0 0.063 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein PPV_E1_C PF00519.12 EMD62184.1 - 0.071 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF815 PF05673.8 EMD62184.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KAR9 PF08580.5 EMD62184.1 - 1.7 6.8 12.6 0.02 13.1 2.4 1.9 2 0 0 2 2 2 0 Yeast cortical protein KAR9 RecR PF02132.10 EMD62185.1 - 0.071 12.5 0.2 2.1 7.8 0.8 2.7 3 0 0 3 3 3 0 RecR protein Cu_amine_oxid PF01179.15 EMD62186.1 - 6.9e-97 324.7 2.2 1.1e-96 324.1 1.5 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EMD62186.1 - 7.3e-19 67.4 0.1 7.3e-19 67.4 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EMD62186.1 - 0.00024 21.1 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 EMD62188.1 - 3.1e-37 128.2 16.4 2.3e-26 92.4 0.6 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EMD62188.1 - 4.4e-22 78.2 13.5 2.1e-21 76.0 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FUSC_2 PF13515.1 EMD62188.1 - 0.0042 16.9 6.3 0.0042 16.9 4.4 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like Acetyltransf_1 PF00583.19 EMD62189.1 - 1.2e-06 28.4 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD62189.1 - 3.3e-06 27.1 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD62189.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD62189.1 - 0.013 15.2 0.0 0.17 11.6 0.0 2.3 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 EMD62189.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_72 PF03198.9 EMD62190.1 - 1.4e-57 195.0 0.1 1.8e-36 125.7 0.0 2.1 1 1 1 2 2 2 2 Glucanosyltransferase DUF4350 PF14258.1 EMD62190.1 - 0.054 13.7 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Cutinase PF01083.17 EMD62191.1 - 5.2e-47 159.8 4.7 6.2e-47 159.6 3.2 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 EMD62191.1 - 0.00032 21.0 0.1 0.0005 20.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EMD62191.1 - 0.0021 17.6 0.2 0.0025 17.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMD62191.1 - 0.0037 16.8 0.1 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EMD62191.1 - 0.034 13.5 0.2 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Chlorophyllase2 PF12740.2 EMD62191.1 - 0.073 11.9 0.3 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EMD62191.1 - 0.15 11.6 2.5 0.37 10.3 1.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_43 PF04616.9 EMD62192.1 - 3.7e-17 62.3 5.5 9.3e-17 61.0 3.1 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMD62192.1 - 0.0014 18.0 0.4 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Pyr_redox_3 PF13738.1 EMD62194.1 - 7.5e-18 65.3 0.1 4.2e-17 62.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD62194.1 - 5.5e-15 54.5 0.0 1.1e-10 40.3 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMD62194.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD62194.1 - 4.4e-11 42.6 1.1 6.8e-09 35.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD62194.1 - 8.4e-07 29.3 0.9 0.0075 16.6 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD62194.1 - 8.6e-07 28.8 0.8 7.8e-06 25.7 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD62194.1 - 6e-06 25.4 0.0 3.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EMD62194.1 - 6.8e-06 25.4 0.2 0.00011 21.4 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EMD62194.1 - 2e-05 23.8 0.9 2e-05 23.8 0.6 1.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EMD62194.1 - 3.9e-05 22.7 6.6 0.0014 17.6 0.9 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD62194.1 - 4e-05 22.2 4.3 0.0002 19.9 0.3 2.8 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EMD62194.1 - 0.00024 20.2 0.2 0.00051 19.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EMD62194.1 - 0.00047 19.1 3.2 0.21 10.4 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMD62194.1 - 0.0019 17.1 0.3 0.0019 17.1 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EMD62194.1 - 0.005 15.9 3.9 0.055 12.5 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMD62194.1 - 0.04 14.1 0.4 0.086 13.1 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EMD62194.1 - 0.074 12.7 1.9 0.82 9.2 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMD62194.1 - 0.39 10.2 2.4 10 5.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EMD62194.1 - 0.9 8.0 4.1 4.9 5.6 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Complex1_LYR PF05347.10 EMD62195.1 - 5.2e-10 38.9 0.4 1e-09 38.0 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD62195.1 - 6.4e-09 35.8 0.1 9.3e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMD62195.1 - 0.051 14.0 0.2 0.075 13.5 0.1 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.19 EMD62196.1 - 1.7e-18 66.4 0.0 3.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD62196.1 - 7.8e-09 35.5 0.0 2.2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD62196.1 - 8.8e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EMD62196.1 - 8.7e-05 22.5 0.0 0.00057 19.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD62196.1 - 0.0002 21.4 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD62196.1 - 0.0044 17.1 0.0 0.0059 16.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD62196.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMD62196.1 - 0.054 13.3 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.22 EMD62197.1 - 2e-47 160.9 0.2 2.7e-24 85.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EMD62197.1 - 1.8e-26 93.0 54.2 1.6e-17 63.6 19.5 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMD62197.1 - 5.9e-24 85.5 1.1 9.4e-10 38.9 0.1 4.5 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EMD62197.1 - 2.1e-10 39.9 0.7 1.3e-05 24.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMD62197.1 - 2.9e-08 33.2 5.4 0.03 13.5 0.0 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMD62197.1 - 1.1e-07 32.3 1.5 0.006 16.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD62197.1 - 6e-05 22.2 0.3 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMD62197.1 - 0.00051 20.1 0.1 0.12 12.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMD62197.1 - 0.00081 19.4 0.7 0.71 9.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EMD62197.1 - 0.0016 17.5 0.0 0.084 11.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EMD62197.1 - 0.0027 17.1 0.1 1.2 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMD62197.1 - 0.012 14.7 1.1 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MutS_V PF00488.16 EMD62197.1 - 0.022 14.1 0.1 2.4 7.5 0.0 2.5 3 0 0 3 3 2 0 MutS domain V AAA_30 PF13604.1 EMD62197.1 - 0.052 13.1 0.6 3.3 7.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMD62197.1 - 0.092 12.1 0.4 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMD62197.1 - 0.11 11.9 0.1 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EMD62197.1 - 0.19 12.1 0.2 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EMD62197.1 - 0.21 11.3 4.3 1.7 8.4 0.1 3.0 3 0 0 3 3 2 0 Part of AAA domain AAA_28 PF13521.1 EMD62197.1 - 0.27 11.1 1.2 3.1 7.7 0.3 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EMD62197.1 - 0.52 9.3 0.5 6 5.9 0.1 2.3 2 0 0 2 2 2 0 AIG1 family G-alpha PF00503.15 EMD62197.1 - 5.4 5.5 3.1 3.1 6.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF2116 PF09889.4 EMD62198.1 - 0.088 12.6 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RPAP2_Rtr1 PF04181.8 EMD62198.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Rtr1/RPAP2 family NAD_binding_10 PF13460.1 EMD62201.1 - 0.00078 19.4 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD62201.1 - 0.0079 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMD62201.1 - 0.046 13.1 0.1 0.084 12.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD62201.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMD62201.1 - 0.16 10.6 0.0 0.33 9.6 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family LRR_4 PF12799.2 EMD62202.1 - 4.9e-08 32.4 4.3 8.3e-07 28.5 0.3 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD62202.1 - 3.3e-05 23.5 3.8 7.1e-05 22.4 2.6 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EMD62202.1 - 0.045 13.7 6.1 1.7 8.9 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EMD62202.1 - 0.074 13.2 3.2 2.6 8.6 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat AA_permease PF00324.16 EMD62203.1 - 7e-107 357.7 37.5 8.8e-107 357.3 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD62203.1 - 5.5e-24 84.4 43.3 6.7e-24 84.2 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease MTTB PF06253.6 EMD62204.1 - 0.14 9.8 0.0 0.19 9.4 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) MFS_1 PF07690.11 EMD62205.1 - 1.4e-33 116.0 33.1 2e-33 115.5 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EMD62205.1 - 0.039 13.9 0.1 0.039 13.9 0.1 3.7 4 2 1 5 5 5 0 Protein of unknown function (DUF1228) DUF4133 PF13571.1 EMD62205.1 - 1.6 8.9 8.1 5.3 7.3 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) Herpes_gE PF02480.11 EMD62206.1 - 0.0018 16.6 0.0 0.0026 16.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Glyco_hydro_7 PF00840.15 EMD62207.1 - 2.1e-206 685.3 20.5 2.5e-206 685.1 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fungal_trans PF04082.13 EMD62208.1 - 3.2e-13 49.1 2.8 5e-13 48.5 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62208.1 - 3.5e-08 33.2 6.7 7.9e-08 32.0 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Terpene_synth_C PF03936.11 EMD62209.1 - 0.00053 19.3 0.0 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Isochorismatase PF00857.15 EMD62212.1 - 9.5e-27 94.0 0.0 1.6e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_7 PF00840.15 EMD62213.1 - 3.3e-138 460.6 13.7 4.1e-138 460.4 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Cu_amine_oxid PF01179.15 EMD62215.1 - 3.4e-103 345.5 4.8 4.4e-103 345.1 3.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EMD62215.1 - 2.7e-25 88.0 0.1 5.2e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EMD62215.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Na_Ca_ex PF01699.19 EMD62217.1 - 3e-47 159.7 34.8 7e-25 87.2 3.7 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein RCR PF12273.3 EMD62217.1 - 9.2 6.8 14.4 4.5 7.8 0.0 4.0 4 0 0 4 4 4 0 Chitin synthesis regulation, resistance to Congo red Cnd2 PF05786.9 EMD62218.1 - 7.5e-216 718.9 1.4 8.5e-216 718.8 0.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Cytochrom_C1 PF02167.10 EMD62221.1 - 7.4e-82 274.2 0.0 9.6e-82 273.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EMD62221.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EMD62221.1 - 0.051 14.4 0.1 0.2 12.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c Peptidase_M1 PF01433.15 EMD62222.1 - 1e-140 469.2 0.5 1.5e-140 468.7 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EMD62222.1 - 6.6e-94 314.7 0.0 2.3e-93 313.0 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMD62222.1 - 4.7e-20 71.9 0.1 1e-19 70.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EMD62222.1 - 0.0054 16.3 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) CTP_transf_1 PF01148.15 EMD62223.1 - 1.3e-06 28.2 14.1 2.1e-05 24.3 1.2 2.9 3 0 0 3 3 3 2 Cytidylyltransferase family DUF3543 PF12063.3 EMD62224.1 - 7.9e-80 267.4 0.1 1.3e-79 266.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EMD62224.1 - 5.4e-62 209.2 0.0 1e-61 208.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62224.1 - 4.1e-44 150.6 0.0 8.7e-44 149.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD62224.1 - 0.042 12.8 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pro_isomerase PF00160.16 EMD62225.1 - 1.5e-51 174.7 0.3 3e-51 173.6 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EMD62225.1 - 7.5e-14 50.9 1.1 2.6e-07 30.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat AAA PF00004.24 EMD62226.1 - 1.9e-42 144.6 0.0 3.2e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD62226.1 - 1e-07 32.1 0.1 4.2e-06 26.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMD62226.1 - 1.4e-06 28.1 0.1 3.2e-05 23.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMD62226.1 - 2.5e-06 27.4 0.0 7.8e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMD62226.1 - 2.7e-06 27.5 0.0 0.001 19.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD62226.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EMD62226.1 - 0.00024 20.0 0.0 0.00063 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMD62226.1 - 0.00032 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMD62226.1 - 0.00058 20.6 0.5 0.0018 19.0 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMD62226.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMD62226.1 - 0.0018 17.0 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EMD62226.1 - 0.0019 18.0 0.0 0.0064 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD62226.1 - 0.0025 18.1 0.1 0.0083 16.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EMD62226.1 - 0.0026 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMD62226.1 - 0.0035 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMD62226.1 - 0.005 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EMD62226.1 - 0.0057 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EMD62226.1 - 0.0073 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EMD62226.1 - 0.0096 15.3 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EMD62226.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMD62226.1 - 0.018 14.1 0.0 0.11 11.5 0.0 2.2 1 1 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 EMD62226.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EMD62226.1 - 0.021 14.4 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMD62226.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EMD62226.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EMD62226.1 - 0.031 13.9 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 EMD62226.1 - 0.032 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EMD62226.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF4200 PF13863.1 EMD62226.1 - 0.042 13.7 0.5 0.042 13.7 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) UPF0079 PF02367.12 EMD62226.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMD62226.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EMD62226.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EMD62226.1 - 0.11 12.0 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EMD62227.1 - 4.1e-18 64.5 7.9 0.00039 20.2 0.0 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EMD62227.1 - 0.2 9.7 0.2 3 5.8 0.1 2.6 1 1 1 3 3 3 0 Nucleoporin Nup120/160 3Beta_HSD PF01073.14 EMD62228.1 - 8.9e-64 214.8 0.0 1e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD62228.1 - 6.6e-38 130.4 0.0 9.1e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMD62228.1 - 2e-17 62.9 1.6 7.7e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EMD62228.1 - 6.5e-16 58.0 0.0 7.7e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMD62228.1 - 2.5e-12 47.0 0.0 5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMD62228.1 - 1.5e-11 43.7 0.0 5.2e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD62228.1 - 5.2e-11 42.8 0.0 8.2e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMD62228.1 - 3e-10 40.0 0.0 6.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMD62228.1 - 3.1e-05 23.3 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family eIF2A PF08662.6 EMD62229.1 - 4.5e-41 140.7 3.8 6.9e-38 130.3 0.2 4.2 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EMD62229.1 - 8.3e-06 25.7 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD62229.1 - 2.4e-05 23.8 0.0 7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD62229.1 - 5.3e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EMD62229.1 - 0.0017 18.1 0.1 0.85 9.6 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ArfGap PF01412.13 EMD62230.1 - 2.5e-34 117.5 0.4 8.3e-34 115.8 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EMD62230.1 - 1.9e-13 50.5 0.1 5.9e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 PH domain ATP11 PF06644.6 EMD62231.1 - 4.2e-75 252.6 0.0 5e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Pex2_Pex12 PF04757.9 EMD62232.1 - 2.4e-40 138.3 3.8 3.2e-40 137.9 2.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EMD62232.1 - 1.7e-11 43.7 8.7 2.7e-11 43.0 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD62232.1 - 6.2e-11 42.1 8.5 9.8e-11 41.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD62232.1 - 6.9e-10 38.4 7.3 1.1e-09 37.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD62232.1 - 7.4e-09 35.1 8.6 1.1e-08 34.5 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD62232.1 - 1.4e-08 34.2 6.3 2.4e-08 33.5 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD62232.1 - 6.1e-06 25.8 1.0 6.1e-06 25.8 0.7 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMD62232.1 - 1.4e-05 24.9 7.9 2.4e-05 24.1 5.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMD62232.1 - 0.00023 21.1 7.3 0.00043 20.3 4.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EMD62232.1 - 0.0078 15.9 5.7 0.016 15.0 3.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EMD62232.1 - 0.028 13.9 1.0 0.055 12.9 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EMD62232.1 - 0.12 12.1 3.6 0.23 11.3 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EMD62232.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 U-box domain Chromo PF00385.19 EMD62233.1 - 2.4e-06 27.1 1.6 2.4e-06 27.1 1.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain HORMA PF02301.13 EMD62233.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 HORMA domain LZ_Tnp_IS66 PF13007.2 EMD62233.1 - 0.37 11.4 4.6 0.82 10.3 1.9 2.7 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain MFS_1 PF07690.11 EMD62234.1 - 2.7e-22 78.9 49.6 2.7e-22 78.9 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMD62234.1 - 0.39 8.7 13.5 0.0081 14.3 3.6 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DUF963 PF06131.6 EMD62237.1 - 0.0011 18.2 9.7 0.0011 18.2 6.7 4.7 1 1 2 3 3 3 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) LHC PF00556.15 EMD62238.1 - 1.1 9.1 4.7 1.6 8.6 3.3 1.3 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Cyclase PF04199.8 EMD62239.1 - 0.027 14.1 0.1 0.25 11.0 0.1 2.2 1 1 0 1 1 1 0 Putative cyclase MFS_1 PF07690.11 EMD62240.1 - 3.9e-18 65.2 52.8 1.7e-15 56.6 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMD62241.1 - 2.7e-36 125.0 27.8 2.7e-36 125.0 19.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Antimicrobial_2 PF08023.7 EMD62241.1 - 0.084 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide Amidohydro_2 PF04909.9 EMD62242.1 - 1.7e-16 60.5 0.1 8.4e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Glyco_hydro_31 PF01055.21 EMD62243.1 - 2.5e-101 339.6 0.4 4.5e-101 338.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 F-box-like PF12937.2 EMD62245.1 - 0.0004 20.0 0.9 0.0009 18.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD62245.1 - 0.028 14.0 0.0 0.079 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain ARL2_Bind_BART PF11527.3 EMD62247.1 - 0.03 14.0 1.4 0.12 12.2 0.1 2.3 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART DUF1572 PF07609.6 EMD62247.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) TPR_10 PF13374.1 EMD62248.1 - 1.3e-28 97.9 0.1 2.8e-11 42.9 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMD62248.1 - 3.2e-22 78.2 0.3 6.8e-12 45.1 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD62248.1 - 2.6e-05 24.0 1.3 0.74 10.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD62248.1 - 2.9e-05 23.5 0.3 0.055 13.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD62248.1 - 0.00038 19.9 1.5 4.8 6.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD62248.1 - 0.0016 18.1 0.2 14 5.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD62248.1 - 0.22 11.6 1.4 12 6.1 1.0 2.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EMD62248.1 - 0.25 11.4 0.9 4.1 7.5 0.0 2.7 3 0 0 3 3 3 0 PPR repeat Glyco_hydro_18 PF00704.23 EMD62250.1 - 3.1e-68 230.7 0.3 6.9e-51 173.7 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD62250.1 - 2.9e-10 39.9 20.0 2.9e-10 39.9 13.9 4.4 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 EMD62251.1 - 5e-21 74.3 6.4 0.0015 18.4 0.0 7.4 8 0 0 8 8 8 6 LysM domain adh_short PF00106.20 EMD62255.1 - 6e-15 55.5 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD62255.1 - 5.5e-07 29.4 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62255.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.5 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD62255.1 - 0.072 13.0 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD62255.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HET PF06985.6 EMD62256.1 - 5.4e-28 97.8 0.7 8.9e-28 97.1 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FYVE PF01363.16 EMD62257.1 - 5.2e-20 71.1 24.4 4.1e-15 55.4 6.2 3.1 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EMD62257.1 - 0.0012 18.9 5.9 0.15 12.1 0.0 3.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Rbsn PF11464.3 EMD62257.1 - 0.0012 18.3 0.1 0.0012 18.3 0.0 2.7 3 0 0 3 3 3 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 EMD62257.1 - 0.0064 16.3 0.7 0.0064 16.3 0.5 3.6 4 0 0 4 4 4 1 AN1-like Zinc finger zf-C2HC5 PF06221.8 EMD62257.1 - 0.18 11.6 17.9 0.26 11.0 0.2 4.2 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type C6_DPF PF10170.4 EMD62257.1 - 0.36 10.9 6.3 0.089 12.8 1.3 2.4 2 0 0 2 2 2 0 Cysteine-rich domain zf-TFIIB PF13453.1 EMD62257.1 - 5.6 6.2 9.8 35 3.7 0.0 3.9 4 0 0 4 4 4 0 Transcription factor zinc-finger IBR PF01485.16 EMD62257.1 - 6.1 6.8 20.6 0.11 12.4 0.3 4.1 3 1 1 4 4 4 0 IBR domain NAD_binding_7 PF13241.1 EMD62258.1 - 2.6e-30 104.7 0.1 4.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMD62258.1 - 3.2e-29 100.0 0.0 4.8e-29 99.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMD62258.1 - 3.2e-14 51.6 0.2 3.2e-14 51.6 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Methyltransf_10 PF05971.7 EMD62259.1 - 3.4e-52 177.4 0.0 4.7e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EMD62259.1 - 2.5e-05 23.7 0.0 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMD62259.1 - 5.4e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62259.1 - 0.0037 17.8 0.0 0.0068 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD62259.1 - 0.0058 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_1c PF00749.16 EMD62261.1 - 1.1e-91 306.8 0.0 1.6e-89 299.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMD62261.1 - 6e-32 110.6 0.0 1.5e-31 109.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fungal_trans_2 PF11951.3 EMD62262.1 - 4.1e-11 42.0 0.0 7.9e-11 41.1 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hydrolase PF00702.21 EMD62263.1 - 1.1e-24 88.0 0.0 5.2e-24 85.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMD62263.1 - 1.2e-19 70.3 0.1 8.6e-19 67.4 0.1 2.3 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMD62263.1 - 4.5e-19 69.3 0.0 8.6e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD62263.1 - 5.6e-06 26.2 0.2 0.00026 20.8 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMD62263.1 - 0.00085 18.9 0.0 0.054 13.0 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD62263.1 - 0.0096 15.3 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD_2 PF13419.1 EMD62265.1 - 1.6e-18 67.5 0.1 2.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD62265.1 - 0.014 15.8 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMD62265.1 - 0.042 13.7 0.0 0.17 11.8 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.16 EMD62265.1 - 0.099 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Radical SAM superfamily DUF4596 PF15363.1 EMD62266.1 - 3 7.8 6.7 0.66 9.9 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Carn_acyltransf PF00755.15 EMD62267.1 - 1e-179 598.4 0.1 1.2e-179 598.2 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ldh_1_N PF00056.18 EMD62268.1 - 1.1e-42 145.2 0.1 1.8e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMD62268.1 - 4.1e-40 137.3 0.0 7.2e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMD62268.1 - 0.0034 16.1 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMD62268.1 - 0.04 14.2 0.3 0.31 11.3 0.0 2.4 2 2 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PGAP1 PF07819.8 EMD62272.1 - 1.3e-86 289.8 0.0 2e-86 289.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMD62272.1 - 6.3e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD62272.1 - 1.9e-05 24.6 0.1 4.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMD62272.1 - 0.0027 17.0 0.1 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EMD62272.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 EMD62272.1 - 0.052 12.5 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ETRAMP PF09716.5 EMD62273.1 - 9.1 6.3 6.5 0.87 9.5 1.6 1.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF663 PF04950.7 EMD62274.1 - 8.9e-92 307.2 2.0 1.6e-91 306.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMD62274.1 - 3.9e-26 90.3 0.0 2.3e-25 87.9 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EMD62274.1 - 3.5e-08 33.1 0.0 4.3e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD62274.1 - 5.1e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMD62274.1 - 0.00016 21.8 0.0 0.00037 20.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD62274.1 - 0.00019 21.5 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EMD62274.1 - 0.00021 21.0 0.3 0.00048 19.8 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EMD62274.1 - 0.00037 20.4 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EMD62274.1 - 0.00061 20.5 0.0 0.00061 20.5 0.0 4.8 4 1 0 4 4 1 1 AAA domain AAA_33 PF13671.1 EMD62274.1 - 0.00066 19.5 1.3 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMD62274.1 - 0.0014 18.9 0.0 0.0049 17.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EMD62274.1 - 0.0018 18.0 0.2 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EMD62274.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EMD62274.1 - 0.0084 15.5 0.0 0.031 13.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMD62274.1 - 0.0088 15.6 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EMD62274.1 - 0.0097 15.6 0.3 0.02 14.6 0.2 1.5 1 0 0 1 1 1 1 NTPase Miro PF08477.8 EMD62274.1 - 0.0099 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein NB-ARC PF00931.17 EMD62274.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EMD62274.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EMD62274.1 - 0.016 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EMD62274.1 - 0.017 14.2 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMD62274.1 - 0.019 14.8 0.1 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD62274.1 - 0.031 14.6 0.0 0.031 14.6 0.0 4.4 4 0 0 4 4 3 0 AAA domain KAP_NTPase PF07693.9 EMD62274.1 - 0.036 13.0 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 EMD62274.1 - 0.059 12.8 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EMD62274.1 - 0.061 13.0 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EMD62274.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EMD62274.1 - 0.19 11.2 0.1 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EMD62274.1 - 3.5 7.5 6.9 6.6 6.6 0.0 3.0 2 1 0 3 3 3 0 AAA domain BCDHK_Adom3 PF10436.4 EMD62275.1 - 5.8e-41 139.7 0.2 7.8e-41 139.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMD62275.1 - 2.7e-15 56.0 0.1 2.6e-09 36.7 0.0 2.6 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMD62275.1 - 0.0096 15.5 0.0 0.4 10.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2427 PF10348.4 EMD62276.1 - 0.91 9.1 6.0 87 2.7 4.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Herpes_gE PF02480.11 EMD62278.1 - 0.062 11.5 0.0 0.091 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E HET PF06985.6 EMD62279.1 - 2.1e-33 115.4 0.7 3.6e-33 114.6 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Macro PF01661.16 EMD62280.1 - 2.9e-39 133.6 0.6 4.2e-39 133.0 0.4 1.3 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.19 EMD62281.1 - 3.8e-108 361.9 23.2 4.4e-108 361.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62281.1 - 3.7e-24 85.1 37.1 3.4e-19 68.7 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF485 PF04341.7 EMD62281.1 - 0.9 9.2 7.3 16 5.3 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Pro_isomerase PF00160.16 EMD62282.1 - 3.3e-47 160.5 0.1 4.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amino_oxidase PF01593.19 EMD62283.1 - 5.8e-52 177.2 0.0 1e-51 176.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD62283.1 - 2.8e-11 43.2 0.1 7.6e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD62283.1 - 1.4e-09 37.3 1.3 2.1e-08 33.4 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD62283.1 - 1.4e-08 35.0 0.8 1.2e-05 25.5 0.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD62283.1 - 5.6e-08 32.0 3.3 9.7e-08 31.2 2.3 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD62283.1 - 6.1e-06 24.9 1.0 1.9e-05 23.3 0.6 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMD62283.1 - 1.1e-05 25.4 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD62283.1 - 3.8e-05 22.9 0.9 5.6e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EMD62283.1 - 4.2e-05 22.8 1.7 5.9e-05 22.3 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMD62283.1 - 5e-05 22.5 1.0 7.8e-05 21.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD62283.1 - 0.00012 22.3 0.7 0.00033 21.0 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD62283.1 - 0.0012 17.8 0.7 0.0021 16.9 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMD62283.1 - 0.029 14.1 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EMD62283.1 - 0.043 14.0 0.1 0.081 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EMD62283.1 - 0.046 13.2 0.8 0.096 12.2 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EMD62283.1 - 0.049 12.5 0.7 0.076 11.9 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EMD62283.1 - 0.12 12.4 0.2 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_2 PF02615.9 EMD62285.1 - 8.8e-99 330.3 0.0 1e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Acetyltransf_1 PF00583.19 EMD62286.1 - 1.7e-15 56.7 0.0 2.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD62286.1 - 3.6e-08 33.4 0.0 7.5e-08 32.4 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD62286.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD62286.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EMD62286.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EMD62286.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD62286.1 - 0.024 14.4 0.0 0.055 13.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_1 PF13232.1 EMD62287.1 - 2.7e-12 46.6 0.6 9.6e-12 44.9 0.2 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMD62287.1 - 1.8e-08 34.0 0.4 4.5e-08 32.7 0.3 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Ank_2 PF12796.2 EMD62288.1 - 8.7e-16 58.0 0.0 2e-07 31.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD62288.1 - 5.3e-12 44.8 3.2 0.00045 19.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMD62288.1 - 2.1e-11 44.0 1.8 1.5e-05 25.3 0.1 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD62288.1 - 1.4e-10 41.0 0.2 0.00053 20.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD62288.1 - 1.4e-08 34.1 3.7 0.026 14.7 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EMD62288.1 - 0.00066 19.2 2.1 0.0028 17.2 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain DUF4140 PF13600.1 EMD62288.1 - 0.81 10.1 8.9 0.33 11.4 3.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EMD62288.1 - 0.81 7.4 2.5 1.3 6.8 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3439 PF11921.3 EMD62288.1 - 6.2 6.5 8.7 0.29 10.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Zn_clus PF00172.13 EMD62289.1 - 2.9e-08 33.4 10.6 4.6e-08 32.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD62290.1 - 1.2e-07 30.8 1.1 2.2e-07 30.0 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 EMD62291.1 - 0.00098 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TetR_C_5 PF08360.6 EMD62291.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Whi5 PF08528.6 EMD62293.1 - 7.7e-12 44.4 0.1 1.2e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Whi5 like AcetylCoA_hydro PF02550.10 EMD62294.1 - 1.1e-49 168.9 0.0 1.7e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EMD62294.1 - 4.5e-39 133.5 0.0 8e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EMD62294.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase Palm_thioest PF02089.10 EMD62295.1 - 1.3e-46 158.7 0.0 1.7e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 EMD62295.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.15 EMD62295.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD62295.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L1 PF00687.16 EMD62297.1 - 2.9e-60 203.3 3.8 2.9e-60 203.3 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family RRN7 PF11781.3 EMD62300.1 - 0.094 12.2 0.6 0.19 11.2 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5a PF01287.15 EMD62301.1 - 3.9e-27 93.9 1.1 5.5e-27 93.5 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EMD62301.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EMD62301.1 - 0.0032 17.1 0.1 0.007 16.0 0.1 1.6 1 0 0 1 1 1 1 KOW motif Vps52 PF04129.7 EMD62302.1 - 1.3e-126 423.1 0.0 1.5e-126 422.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EMD62302.1 - 0.00019 19.7 0.7 0.00028 19.1 0.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 EMD62302.1 - 0.013 15.3 0.6 0.031 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EMD62302.1 - 0.19 11.6 3.6 2.3 8.0 0.3 3.3 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4298 PF14131.1 EMD62302.1 - 0.43 10.4 3.2 0.76 9.6 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) DUF1993 PF09351.5 EMD62303.1 - 3.5e-27 95.3 0.0 4e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) 2OG-FeII_Oxy_3 PF13640.1 EMD62304.1 - 3e-09 37.2 0.0 6.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMD62304.1 - 6.8e-06 25.6 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Marek_A PF02124.10 EMD62304.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Marek's disease glycoprotein A CLASP_N PF12348.3 EMD62305.1 - 1.5e-119 397.3 6.7 1.6e-85 286.0 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EMD62305.1 - 0.014 15.4 3.3 28 5.1 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Thi4 PF01946.12 EMD62306.1 - 2.4e-104 347.4 0.0 3.2e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMD62306.1 - 3.5e-08 32.7 0.1 3.6e-07 29.4 0.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD62306.1 - 3e-05 23.1 2.5 7.9e-05 21.7 0.2 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMD62306.1 - 8.8e-05 22.3 0.9 0.00019 21.2 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD62306.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD62306.1 - 0.00031 20.7 0.4 0.00093 19.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD62306.1 - 0.00031 19.6 1.8 0.0034 16.3 0.8 2.5 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD62306.1 - 0.00049 20.2 0.2 0.00069 19.7 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD62306.1 - 0.032 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EMD62306.1 - 0.035 13.1 0.6 0.057 12.4 0.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase RhoGAP PF00620.22 EMD62308.1 - 7.8e-46 155.4 0.0 2.2e-45 153.9 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EMD62308.1 - 8.6e-14 51.3 18.5 2.7e-09 36.9 1.2 2.4 2 0 0 2 2 2 2 LIM domain DUF4140 PF13600.1 EMD62308.1 - 0.034 14.5 0.5 0.034 14.5 0.4 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Desulfoferrod_N PF06397.7 EMD62308.1 - 0.35 10.3 12.3 7.8 5.9 1.3 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.5 EMD62308.1 - 0.66 9.9 18.6 0.38 10.7 1.0 4.2 3 1 0 3 3 3 0 Zinc ribbon domain TMF_TATA_bd PF12325.3 EMD62308.1 - 2.4 7.9 15.3 0.63 9.7 0.5 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EMD62308.1 - 6.3 4.5 8.8 7.3 4.3 4.1 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EMD62308.1 - 9.3 5.8 10.7 20 4.7 6.8 2.0 1 1 1 2 2 2 0 Mnd1 family Gly-zipper_OmpA PF13436.1 EMD62309.1 - 0.19 11.4 4.8 0.42 10.2 3.4 1.6 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF4190 PF13828.1 EMD62309.1 - 0.19 11.2 5.4 0.3 10.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Cas_Csy4 PF09618.5 EMD62309.1 - 0.23 11.2 1.2 0.32 10.7 0.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) RNase_H2-Ydr279 PF09468.5 EMD62309.1 - 1.2 8.2 6.2 1.5 7.9 4.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) ETRAMP PF09716.5 EMD62309.1 - 1.5 8.8 6.8 0.12 12.3 1.3 1.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Mitofilin PF09731.4 EMD62309.1 - 2.4 6.7 10.1 2.9 6.4 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 EMD62309.1 - 2.4 7.9 7.5 2.9 7.7 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.9 EMD62309.1 - 2.8 6.7 8.0 3.6 6.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) vATP-synt_E PF01991.13 EMD62309.1 - 3.7 6.7 10.1 5.4 6.2 7.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Herpes_DNAp_acc PF04929.7 EMD62309.1 - 8.2 5.2 8.4 10 4.9 5.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CHCH PF06747.8 EMD62310.1 - 7.3e-06 25.7 4.7 1.3e-05 24.9 3.3 1.4 1 0 0 1 1 1 1 CHCH domain SWIRM PF04433.12 EMD62311.1 - 2.1e-32 111.0 0.1 4.5e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EMD62311.1 - 9.1e-09 35.2 0.7 1.9e-08 34.2 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD62311.1 - 1.5e-06 28.1 0.2 3.3e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF904 PF06005.7 EMD62311.1 - 0.95 9.7 5.2 0.29 11.4 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ETF PF01012.16 EMD62312.1 - 1.8e-41 141.5 0.7 4.6e-41 140.2 0.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EMD62312.1 - 1.7e-34 117.2 0.1 3.9e-34 116.1 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ion_trans_2 PF07885.11 EMD62313.1 - 3.7e-27 93.8 19.6 1.1e-15 57.0 5.9 3.6 4 1 1 5 5 5 2 Ion channel DUF2339 PF10101.4 EMD62313.1 - 0.28 9.4 20.8 0.63 8.2 3.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) DUF360 PF04020.8 EMD62313.1 - 0.58 10.5 7.4 0.5 10.7 2.0 2.6 2 0 0 2 2 2 0 Membrane protein of unknown function Lig_chan PF00060.21 EMD62313.1 - 1.9 8.1 8.9 0.47 10.1 1.5 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel ABC_membrane PF00664.18 EMD62314.1 - 5.2e-77 258.9 37.4 1.5e-39 136.1 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD62314.1 - 2.5e-63 212.4 0.1 2.6e-34 118.4 0.0 3.4 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.14 EMD62314.1 - 1e-15 57.5 2.3 6.5e-06 25.5 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD62314.1 - 3.6e-12 46.8 0.0 0.11 12.4 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EMD62314.1 - 3.7e-08 32.7 1.5 0.00032 20.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD62314.1 - 8.3e-08 32.4 1.2 0.017 15.2 0.1 3.5 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EMD62314.1 - 1.7e-07 30.2 0.1 0.1 11.1 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMD62314.1 - 6e-07 29.6 5.7 0.00016 21.6 0.5 2.7 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EMD62314.1 - 9.9e-07 28.0 0.0 0.052 12.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMD62314.1 - 2.2e-06 28.5 0.1 0.062 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD62314.1 - 2e-05 24.0 0.0 0.41 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMD62314.1 - 2.5e-05 23.8 1.2 0.65 9.3 0.1 3.9 4 0 0 4 4 3 1 AAA-like domain AAA_30 PF13604.1 EMD62314.1 - 6.3e-05 22.6 1.9 0.13 11.8 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EMD62314.1 - 0.00043 20.6 3.4 0.0094 16.2 0.2 2.8 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EMD62314.1 - 0.0015 18.4 1.3 0.16 11.9 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMD62314.1 - 0.0023 17.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD62314.1 - 0.0026 18.0 0.5 4.8 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMD62314.1 - 0.0036 17.0 0.1 0.26 11.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EMD62314.1 - 0.0044 16.9 0.1 11 5.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain MobB PF03205.9 EMD62314.1 - 0.0083 15.8 1.3 1.7 8.3 0.0 3.5 5 0 0 5 5 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EMD62314.1 - 0.011 15.4 0.1 3.9 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMD62314.1 - 0.02 14.8 0.6 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMD62314.1 - 0.03 14.2 0.0 7.5 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 EMD62314.1 - 0.033 13.9 2.8 5.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 SRP54 PF00448.17 EMD62314.1 - 0.034 13.5 0.1 4.2 6.7 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EMD62314.1 - 0.048 13.1 0.1 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EMD62314.1 - 0.055 13.6 0.1 16 5.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EMD62314.1 - 0.077 12.0 2.9 1.2 8.2 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin Rad17 PF03215.10 EMD62314.1 - 0.094 11.3 0.1 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_15 PF13175.1 EMD62314.1 - 0.26 10.2 1.4 4.1 6.3 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain Myb_DNA-binding PF00249.26 EMD62316.1 - 2.4e-31 107.5 10.8 2.8e-13 49.6 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD62316.1 - 1.1e-28 99.1 8.3 5.9e-14 51.9 0.6 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EMD62316.1 - 0.0035 17.5 6.8 0.72 10.0 0.0 3.9 4 0 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.5 EMD62316.1 - 0.12 12.0 0.0 0.35 10.6 0.0 1.6 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_5 PF13873.1 EMD62316.1 - 0.24 11.3 7.8 19 5.2 0.1 3.9 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain rRNA_processing PF08524.6 EMD62317.1 - 0.42 10.3 32.1 57 3.4 22.2 2.3 1 1 0 1 1 1 0 rRNA processing DUF4210 PF13915.1 EMD62318.1 - 3e-26 91.5 0.0 8.9e-26 89.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EMD62318.1 - 8.3e-23 80.0 0.9 2e-22 78.8 0.6 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis Rhodanese PF00581.15 EMD62318.1 - 1e-14 54.8 0.0 3.4e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain BSP PF04450.7 EMD62319.1 - 7.5e-76 254.1 0.0 8.3e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EMD62319.1 - 1.4e-06 28.3 0.9 6.6e-05 22.9 0.1 2.1 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 EMD62319.1 - 8.5e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 SprT-like family HAD_2 PF13419.1 EMD62320.1 - 7.1e-34 117.5 0.3 8.6e-34 117.2 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD62320.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMD62320.1 - 4e-06 27.3 0.0 7e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase KH_1 PF00013.24 EMD62322.1 - 1.5e-30 104.6 1.0 1.1e-07 31.4 0.2 6.8 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EMD62322.1 - 1.3e-26 91.7 4.7 1.3e-07 31.0 0.0 6.3 6 0 0 6 6 6 4 KH domain GYF PF02213.11 EMD62323.1 - 7.3e-18 63.9 0.0 1.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 GYF domain Homeobox PF00046.24 EMD62323.1 - 0.32 10.6 2.9 0.73 9.5 2.0 1.6 1 0 0 1 1 1 0 Homeobox domain MFS_1 PF07690.11 EMD62325.1 - 2.3e-32 112.0 27.5 2.3e-32 112.0 19.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SNARE_assoc PF09335.6 EMD62326.1 - 3.6e-17 62.7 9.7 3.6e-17 62.7 6.7 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein GRIM-19 PF06212.7 EMD62326.1 - 0.0075 15.9 0.2 4.8 6.8 0.0 3.1 3 0 0 3 3 3 1 GRIM-19 protein DUF1469 PF07332.6 EMD62326.1 - 0.011 15.5 7.4 0.51 10.0 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Shisa PF13908.1 EMD62326.1 - 0.12 12.4 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator YrhC PF14143.1 EMD62326.1 - 0.64 10.0 3.7 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 YrhC-like protein GATase_4 PF13230.1 EMD62327.1 - 7.3e-13 47.8 0.2 5.1e-12 45.0 0.2 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMD62327.1 - 5.9e-10 39.2 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMD62327.1 - 1.5e-05 23.8 0.1 2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 EMD62327.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF2004 PF09406.5 EMD62327.1 - 0.092 12.8 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) AA_permease PF00324.16 EMD62329.1 - 5.2e-96 321.8 36.6 6.6e-96 321.5 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD62329.1 - 1.1e-26 93.3 37.2 1.4e-26 93.0 25.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EMD62329.1 - 0.52 10.0 8.7 0.28 10.8 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DctQ PF04290.7 EMD62330.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component YEATS PF03366.11 EMD62331.1 - 1.4e-11 43.9 0.2 2.1e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family zf-RING_2 PF13639.1 EMD62331.1 - 2.4e-07 30.4 5.8 4e-07 29.7 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EMD62331.1 - 3.2e-06 26.8 2.5 3.2e-06 26.8 1.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMD62331.1 - 1.1e-05 25.3 5.8 5.4e-05 23.1 4.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD62331.1 - 5.1e-05 22.8 6.2 0.00015 21.3 4.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD62331.1 - 7.3e-05 22.3 3.0 7.3e-05 22.3 2.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD62331.1 - 0.0025 17.4 8.3 0.017 14.8 5.9 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD62331.1 - 0.0025 17.4 2.9 0.0025 17.4 2.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 EMD62331.1 - 0.12 11.8 7.6 0.069 12.6 1.9 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-piccolo PF05715.8 EMD62331.1 - 0.21 11.6 6.4 0.67 10.0 1.1 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger PBP1_TM PF14812.1 EMD62331.1 - 0.23 11.7 3.8 0.25 11.6 1.8 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Apc11 PF12861.2 EMD62331.1 - 0.89 9.4 5.1 7.6 6.4 1.7 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1191 PF06697.7 EMD62332.1 - 0.028 13.2 0.1 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4519 PF15012.1 EMD62332.1 - 0.031 14.1 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ABC_membrane PF00664.18 EMD62333.1 - 2.1e-79 266.8 33.3 2.1e-41 142.1 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD62333.1 - 7e-67 223.9 0.0 4.8e-32 111.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD62333.1 - 1.5e-13 50.5 7.6 1.7e-05 24.1 0.9 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD62333.1 - 1e-12 48.6 0.0 0.00022 21.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EMD62333.1 - 2.4e-10 40.7 2.1 0.00024 21.1 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EMD62333.1 - 7.7e-10 37.9 4.1 5.5e-05 21.9 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EMD62333.1 - 2.3e-08 33.4 1.8 0.00048 19.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMD62333.1 - 1.9e-07 30.3 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMD62333.1 - 7.2e-07 30.0 0.0 0.08 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD62333.1 - 6e-06 26.4 2.5 0.25 11.5 0.2 4.0 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EMD62333.1 - 6.5e-06 25.9 2.0 0.11 12.4 0.1 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EMD62333.1 - 9e-05 21.9 0.5 0.35 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EMD62333.1 - 0.00035 20.4 0.0 1.2 8.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EMD62333.1 - 0.00049 20.1 0.0 0.099 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD62333.1 - 0.00084 19.2 0.1 2 8.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMD62333.1 - 0.0014 17.8 0.1 0.2 10.7 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 EMD62333.1 - 0.0015 18.2 0.2 1.7 8.3 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMD62333.1 - 0.0025 18.1 0.0 3.8 7.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 EMD62333.1 - 0.0032 17.1 0.1 0.17 11.5 0.1 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.1 EMD62333.1 - 0.012 15.9 0.3 4.6 7.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EMD62333.1 - 0.012 14.2 0.0 2.8 6.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 EMD62333.1 - 0.024 14.1 0.6 2.2 7.7 0.1 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EMD62333.1 - 0.037 13.7 0.1 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMD62333.1 - 0.04 14.0 0.0 4.6 7.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 EMD62333.1 - 0.052 13.5 0.0 7.3 6.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 EMD62333.1 - 0.053 13.3 0.8 1.7 8.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EMD62333.1 - 0.067 12.6 3.7 2.5 7.4 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain Fungal_trans PF04082.13 EMD62334.1 - 1.7e-15 56.6 0.1 3.1e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62334.1 - 5.6e-08 32.5 14.2 1.1e-07 31.5 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MTD PF01993.13 EMD62335.1 - 0.012 14.6 10.4 1.6 7.6 0.1 4.4 3 1 0 4 4 4 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Pox_A_type_inc PF04508.7 EMD62335.1 - 0.38 10.6 3.4 36 4.5 0.0 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat P53 PF00870.13 EMD62335.1 - 0.66 9.5 6.6 33 3.9 0.2 4.1 4 0 0 4 4 4 0 P53 DNA-binding domain Basic PF01586.11 EMD62335.1 - 5.1 7.8 36.6 8.7 7.1 0.8 6.6 1 1 5 6 6 6 0 Myogenic Basic domain DUF3328 PF11807.3 EMD62336.1 - 2.7e-52 177.5 0.8 3.3e-52 177.3 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) dsrm PF00035.20 EMD62337.1 - 4.7e-08 33.4 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EMD62337.1 - 0.00014 22.3 0.0 0.0003 21.1 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMD62337.1 - 0.00024 21.0 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease-III-like PfkB PF00294.19 EMD62338.1 - 5e-11 42.2 0.0 5.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.14 EMD62339.1 - 4e-83 279.2 0.1 5.8e-83 278.7 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EMD62339.1 - 9.2e-60 200.5 1.1 1.3e-59 200.1 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EMD62339.1 - 0.0028 17.0 2.8 0.012 15.0 2.1 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C Pkinase PF00069.20 EMD62340.1 - 2e-22 79.5 0.0 3.1e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62340.1 - 6.7e-15 54.8 0.0 1.3e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_5 PF00266.14 EMD62343.1 - 9.7e-21 73.9 0.0 7.9e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMD62343.1 - 1.9e-05 23.8 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD62343.1 - 0.013 13.8 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Eaf7 PF07904.8 EMD62345.1 - 1.5e-28 98.5 0.1 1.5e-28 98.5 0.1 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 FAM176 PF14851.1 EMD62345.1 - 3.2 7.4 5.9 6.3 6.4 4.1 1.5 1 0 0 1 1 1 0 FAM176 family Spc97_Spc98 PF04130.8 EMD62346.1 - 2.4e-72 243.9 0.5 3.3e-72 243.5 0.3 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3658 PF12395.3 EMD62346.1 - 0.028 13.9 0.0 0.096 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function ABC_tran PF00005.22 EMD62347.1 - 8.2e-48 162.1 0.0 5.3e-24 85.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD62347.1 - 4.4e-16 58.7 0.0 2.9e-06 26.6 0.0 3.7 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD62347.1 - 2.4e-15 57.3 0.2 0.0022 17.9 0.1 4.4 3 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 EMD62347.1 - 4.7e-10 40.1 0.1 0.00029 21.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMD62347.1 - 1.6e-09 37.1 0.0 0.00084 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD62347.1 - 1.1e-07 32.0 0.0 0.0019 18.3 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EMD62347.1 - 1.8e-07 31.2 0.0 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD62347.1 - 2e-07 30.3 0.0 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMD62347.1 - 2.2e-07 31.7 0.0 0.0029 18.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 EMD62347.1 - 1.1e-06 27.4 0.2 0.72 8.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EMD62347.1 - 2.4e-06 27.6 1.4 0.39 10.6 0.0 4.8 5 0 0 5 5 5 2 AAA ATPase domain PduV-EutP PF10662.4 EMD62347.1 - 4.5e-06 26.2 0.0 0.14 11.5 0.0 3.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EMD62347.1 - 4.7e-06 26.8 0.1 0.13 12.4 0.0 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EMD62347.1 - 1.2e-05 25.1 0.0 0.046 13.6 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EMD62347.1 - 1.2e-05 25.1 0.0 0.019 14.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EMD62347.1 - 1.3e-05 24.7 0.1 0.31 10.4 0.0 3.4 4 0 0 4 4 3 2 AAA-like domain Miro PF08477.8 EMD62347.1 - 1.5e-05 25.4 0.1 0.03 14.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EMD62347.1 - 5e-05 23.0 0.0 0.56 9.9 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMD62347.1 - 5.1e-05 23.1 0.0 0.28 11.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EMD62347.1 - 5.2e-05 23.0 0.1 0.21 11.2 0.0 3.1 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 EMD62347.1 - 5.3e-05 22.9 0.0 0.059 13.0 0.0 2.8 2 1 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.20 EMD62347.1 - 5.6e-05 22.7 0.0 0.077 12.4 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EMD62347.1 - 9.5e-05 22.5 0.0 0.43 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EMD62347.1 - 9.7e-05 22.6 0.4 0.31 11.3 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EMD62347.1 - 0.00014 21.7 0.1 0.54 10.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain ArgK PF03308.11 EMD62347.1 - 0.00016 20.5 0.1 0.12 11.1 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 EMD62347.1 - 0.0002 21.2 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EMD62347.1 - 0.00033 20.5 0.7 0.13 12.0 0.0 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 cobW PF02492.14 EMD62347.1 - 0.00074 19.0 0.1 0.46 9.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain HEAT_2 PF13646.1 EMD62347.1 - 0.00084 19.5 6.4 2.1 8.6 0.0 3.7 1 1 3 4 4 4 1 HEAT repeats AAA_30 PF13604.1 EMD62347.1 - 0.00098 18.7 0.0 1.8 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EMD62347.1 - 0.0016 17.4 0.0 0.47 9.2 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.1 EMD62347.1 - 0.0032 16.5 7.3 0.65 8.9 0.0 4.1 3 2 0 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 EMD62347.1 - 0.0041 16.5 0.0 3.8 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EMD62347.1 - 0.0062 16.1 0.0 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adaptin_N PF01602.15 EMD62347.1 - 0.0072 14.7 3.5 0.049 11.9 1.4 2.4 1 1 1 2 2 2 1 Adaptin N terminal region IstB_IS21 PF01695.12 EMD62347.1 - 0.0096 15.3 0.1 13 5.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.1 EMD62347.1 - 0.017 14.8 2.2 5.3 6.8 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain NB-ARC PF00931.17 EMD62347.1 - 0.017 13.9 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 EMD62347.1 - 0.026 13.5 0.1 1.9 7.3 0.0 2.7 3 0 0 3 3 2 0 Septin UPF0079 PF02367.12 EMD62347.1 - 0.033 13.7 0.0 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EMD62347.1 - 0.035 13.8 0.0 12 5.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMD62347.1 - 0.038 13.1 0.0 4 6.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Arf PF00025.16 EMD62347.1 - 0.069 12.3 0.0 13 5.0 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Cnd1 PF12717.2 EMD62347.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EMD62347.1 - 0.11 12.3 1.9 2.3 8.0 0.2 2.9 2 1 1 3 3 2 0 Parkin co-regulated protein FtsK_SpoIIIE PF01580.13 EMD62347.1 - 0.17 11.3 2.3 2.6 7.4 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family HEAT PF02985.17 EMD62347.1 - 0.24 11.5 1.1 23 5.4 0.0 4.0 3 0 0 3 3 2 0 HEAT repeat HET PF06985.6 EMD62348.1 - 3.8e-29 101.6 0.0 5.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rick_17kDa_Anti PF05433.10 EMD62350.1 - 0.00017 21.1 21.3 0.00032 20.2 14.8 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMD62350.1 - 0.011 15.3 4.6 0.03 13.9 3.2 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 EMD62350.1 - 0.014 14.7 2.1 0.035 13.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gly-zipper_YMGG PF13441.1 EMD62350.1 - 0.018 14.5 14.8 0.038 13.5 10.3 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EMD62350.1 - 0.019 14.5 13.2 0.019 14.5 9.1 1.8 1 1 1 2 2 2 0 Glycine zipper TraT PF05818.7 EMD62350.1 - 0.043 13.2 0.1 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein TPR_11 PF13414.1 EMD62351.1 - 1.5e-17 62.9 14.0 2.4e-09 36.6 0.1 6.3 5 1 1 6 6 6 2 TPR repeat TPR_1 PF00515.23 EMD62351.1 - 3.8e-10 38.9 11.0 0.0002 20.8 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD62351.1 - 5.5e-10 38.3 20.9 0.00016 21.3 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD62351.1 - 6.2e-07 29.9 1.9 6.2e-07 29.9 1.3 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD62351.1 - 4.6e-06 26.0 2.8 0.033 13.9 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD62351.1 - 3.9e-05 23.9 22.1 0.00028 21.2 0.1 6.3 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMD62351.1 - 8.1e-05 22.3 2.0 8.1e-05 22.3 1.4 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD62351.1 - 0.00093 19.0 20.2 0.13 12.2 2.6 6.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMD62351.1 - 0.0029 17.8 8.6 5.1 7.5 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD62351.1 - 0.012 15.3 13.3 4 7.4 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD62351.1 - 0.023 14.8 6.9 2 8.8 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD62351.1 - 0.21 11.7 4.9 3.7 7.7 1.6 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Filament PF00038.16 EMD62354.1 - 9.1e-10 38.4 200.7 0.022 14.2 11.0 9.4 1 1 8 9 9 9 8 Intermediate filament protein CENP-F_leu_zip PF10473.4 EMD62354.1 - 6.8e-06 25.9 244.0 0.005 16.6 11.5 12.4 1 1 13 14 14 14 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMD62354.1 - 1.9e-05 22.6 248.3 0.011 13.5 29.7 5.2 1 1 4 5 5 5 4 Myosin tail Pox_A_type_inc PF04508.7 EMD62354.1 - 4.4e-05 22.9 63.8 0.059 13.1 0.1 17.6 17 2 2 19 19 19 3 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 EMD62354.1 - 0.00016 20.9 134.9 0.0033 16.6 8.4 9.6 1 1 7 9 9 9 8 Reovirus sigma C capsid protein Tup_N PF08581.5 EMD62354.1 - 0.00039 20.5 4.2 0.00039 20.5 2.9 12.3 8 6 4 13 13 13 2 Tup N-terminal DUF4200 PF13863.1 EMD62354.1 - 0.0076 16.1 11.9 0.0076 16.1 8.3 12.9 2 2 12 14 14 14 4 Domain of unknown function (DUF4200) TSC22 PF01166.13 EMD62354.1 - 0.011 15.6 0.2 0.011 15.6 0.1 13.8 12 3 2 14 14 14 0 TSC-22/dip/bun family AAA_13 PF13166.1 EMD62354.1 - 2 6.8 203.8 0.024 13.1 13.6 7.3 1 1 7 8 8 8 0 AAA domain IncA PF04156.9 EMD62354.1 - 3.6 7.1 212.3 7.2 6.1 14.4 11.0 1 1 7 8 8 8 0 IncA protein zf-RING_2 PF13639.1 EMD62356.1 - 2.2e-15 56.1 19.1 2e-13 49.9 6.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EMD62356.1 - 4e-11 42.4 10.9 2.1e-08 33.6 3.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD62356.1 - 3.2e-09 36.6 17.6 5.2e-07 29.5 6.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD62356.1 - 7.5e-09 35.1 16.5 3.2e-06 26.6 6.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EMD62356.1 - 1.6e-06 28.0 10.1 3.9e-05 23.5 2.8 2.7 2 0 0 2 2 2 2 zinc-finger zf-rbx1 PF12678.2 EMD62356.1 - 1.9e-06 27.9 5.7 1.9e-06 27.9 4.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMD62356.1 - 1.9e-06 27.4 13.3 1.6e-05 24.4 4.4 2.3 2 0 0 2 2 2 2 zinc-RING finger domain HypA PF01155.14 EMD62356.1 - 0.0047 16.6 0.7 0.0047 16.6 0.5 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 EMD62356.1 - 0.085 12.4 12.4 0.69 9.5 3.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EMD62356.1 - 0.09 12.6 6.1 0.093 12.5 0.7 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 EMD62356.1 - 0.12 12.1 12.2 0.34 10.6 0.2 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF1272 PF06906.6 EMD62356.1 - 0.3 10.9 7.6 0.55 10.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EMD62356.1 - 0.39 10.6 15.1 0.22 11.3 0.8 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PhnA_Zn_Ribbon PF08274.7 EMD62356.1 - 0.47 10.2 10.2 2.2 8.1 0.5 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon UPF0547 PF10571.4 EMD62356.1 - 0.53 10.0 4.2 13 5.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.7 EMD62356.1 - 0.99 9.5 7.2 11 6.2 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Apc11 PF12861.2 EMD62356.1 - 1.4 8.7 10.5 0.091 12.6 3.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ribbon_3 PF13248.1 EMD62356.1 - 2.6 7.3 6.9 18 4.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EMD62356.1 - 3 7.7 6.5 4.6 7.1 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbons GCC2_GCC3 PF07699.8 EMD62356.1 - 4.7 6.8 7.2 0.55 9.8 0.1 2.7 3 0 0 3 3 3 0 GCC2 and GCC3 Fis1_TPR_C PF14853.1 EMD62357.1 - 2.4e-25 88.1 2.4 3.8e-25 87.5 1.7 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EMD62357.1 - 2.1e-17 62.1 0.0 3.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EMD62357.1 - 0.00054 19.6 4.4 0.0011 18.6 3.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD62357.1 - 0.0047 17.5 0.9 0.0082 16.7 0.6 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD62357.1 - 0.013 15.0 0.3 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EMD62357.1 - 0.097 13.1 0.4 0.27 11.7 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD62357.1 - 0.25 10.9 4.8 0.53 9.9 3.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EMD62358.1 - 6.4e-37 125.8 0.2 2.7e-35 120.5 0.0 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 DUF3080 PF11279.3 EMD62358.1 - 0.015 14.5 1.0 0.019 14.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF167 PF02594.11 EMD62358.1 - 0.053 13.4 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 Sas10_Utp3 PF04000.10 EMD62358.1 - 0.16 12.1 1.2 0.41 10.8 0.2 2.0 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Solute_trans_a PF03619.11 EMD62360.1 - 4e-102 341.2 9.4 4.9e-102 340.9 6.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Exo_endo_phos PF03372.18 EMD62363.1 - 3.5e-11 43.5 0.3 5e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EMD62364.1 - 5.1e-38 130.6 25.6 7.8e-38 130.0 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.1 EMD62364.1 - 0.072 12.4 0.1 0.32 10.3 0.1 2.1 1 1 0 1 1 1 0 Neurensin adh_short PF00106.20 EMD62365.1 - 3.2e-29 101.9 1.3 4.3e-29 101.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62365.1 - 9.9e-25 87.7 1.4 1.2e-24 87.4 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62365.1 - 1.8e-11 44.0 0.2 2.9e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62365.1 - 2.5e-05 23.8 0.9 6.2e-05 22.5 0.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 EMD62365.1 - 0.045 13.9 0.5 0.32 11.1 0.3 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain DASH_Ask1 PF08655.5 EMD62366.1 - 5.5e-33 112.5 0.0 8.7e-33 111.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PI3_PI4_kinase PF00454.22 EMD62367.1 - 1.5e-39 135.8 0.0 2.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EMD62368.1 - 2.9e-68 229.8 0.1 4.7e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD62368.1 - 9.5e-09 35.0 0.1 5.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMD62368.1 - 0.0021 17.7 1.3 0.0041 16.8 0.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD_2 PF06733.10 EMD62368.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 HET PF06985.6 EMD62369.1 - 5.3e-21 75.2 11.8 4.5e-19 69.0 7.1 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 EMD62370.1 - 3.1e-45 154.5 12.5 5.7e-45 153.6 8.7 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD62370.1 - 7.7e-14 52.0 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1889 PF08986.5 EMD62370.1 - 0.045 13.9 0.6 5.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1889) HARE-HTH PF05066.8 EMD62372.1 - 0.049 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Asp PF00026.18 EMD62373.1 - 1.2e-27 96.9 0.9 1.5e-27 96.7 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Thiolase_N PF00108.18 EMD62374.1 - 2.5e-72 243.0 0.3 4.5e-72 242.1 0.2 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD62374.1 - 2.3e-41 140.0 1.3 3.8e-41 139.3 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMD62374.1 - 0.086 12.5 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pex14_N PF04695.8 EMD62375.1 - 0.3 11.1 4.7 0.38 10.7 3.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4589 PF15252.1 EMD62375.1 - 3.3 7.4 11.6 4 7.2 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) ApbA PF02558.11 EMD62378.1 - 5.9e-31 106.9 0.0 1.2e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EMD62378.1 - 2.3e-26 92.2 0.0 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 EMD62378.1 - 0.0023 16.8 0.3 0.0035 16.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EMD62378.1 - 0.13 12.0 1.0 0.19 11.5 0.3 1.6 2 0 0 2 2 2 0 ThiF family Yip1 PF04893.12 EMD62380.1 - 1.1e-11 44.4 15.5 2.3e-11 43.4 10.8 1.5 1 1 0 1 1 1 1 Yip1 domain CopD PF05425.8 EMD62380.1 - 0.19 11.9 12.4 0.79 9.9 0.7 2.5 2 0 0 2 2 2 0 Copper resistance protein D GATA PF00320.22 EMD62381.1 - 1.6e-14 52.9 4.4 3.1e-14 52.0 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EMD62381.1 - 4.8e-08 32.9 0.0 9.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMD62381.1 - 6.8e-07 29.2 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.1 EMD62381.1 - 7.6e-05 23.0 0.0 0.00021 21.6 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMD62381.1 - 9.6e-05 22.1 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EMD62381.1 - 0.0012 18.8 0.0 0.0041 17.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold HisKA PF00512.20 EMD62382.1 - 9.2e-09 35.1 0.8 9.6e-09 35.1 0.6 1.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF3347 PF11827.3 EMD62382.1 - 0.05 13.6 0.1 0.052 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Phosphorylase PF00343.15 EMD62383.1 - 0 1079.8 0.6 0 1079.6 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase UPF0121 PF03661.8 EMD62386.1 - 6.4e-11 41.9 1.3 8.2e-11 41.5 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Septin PF00735.13 EMD62387.1 - 2.7e-122 407.1 1.5 2.7e-122 407.1 1.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMD62387.1 - 1.7e-07 31.1 0.2 3.9e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD62387.1 - 1e-05 25.0 1.8 0.001 18.5 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMD62387.1 - 3.4e-05 23.0 0.3 0.00027 20.1 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMD62387.1 - 0.00035 19.7 0.1 0.00035 19.7 0.0 2.7 2 1 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 EMD62387.1 - 0.00045 20.5 5.0 0.016 15.5 0.0 2.7 2 1 1 3 3 3 1 ABC transporter Ras PF00071.17 EMD62387.1 - 0.0021 17.4 0.0 0.0097 15.3 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.1 EMD62387.1 - 0.0023 17.9 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EMD62387.1 - 0.0029 17.1 4.8 0.016 14.7 3.3 2.2 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EMD62387.1 - 0.0029 18.0 1.2 0.013 16.0 0.0 2.7 3 1 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 EMD62387.1 - 0.005 16.9 0.1 0.03 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMD62387.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMD62387.1 - 0.0069 15.8 1.2 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 EMD62387.1 - 0.017 15.3 1.8 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EMD62387.1 - 0.062 12.9 0.1 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EMD62387.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain Phage_GPO PF05929.6 EMD62387.1 - 0.15 11.2 7.3 0.25 10.5 5.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynamin_N PF00350.18 EMD62387.1 - 0.24 11.1 12.8 0.5 10.1 0.1 3.8 3 2 1 4 4 2 0 Dynamin family NTNH_C PF08470.5 EMD62387.1 - 0.28 10.8 4.6 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal AbiH PF14253.1 EMD62387.1 - 0.82 9.2 8.1 2.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH KfrA_N PF11740.3 EMD62387.1 - 2.9 8.3 8.9 5.2 7.5 6.2 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF87 PF01935.12 EMD62387.1 - 8.1 6.1 9.1 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Exo70 PF03081.10 EMD62388.1 - 7.7e-81 271.7 1.7 1e-80 271.2 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit CCDC-167 PF15188.1 EMD62388.1 - 0.04 13.8 0.1 0.55 10.2 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2935 PF11155.3 EMD62388.1 - 0.18 11.9 1.5 0.75 9.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.7 EMD62388.1 - 1.2 9.3 6.5 7.6 6.8 0.1 4.6 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein CorA PF01544.13 EMD62389.1 - 6.4e-10 38.5 0.5 1.1e-09 37.7 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SieB PF14163.1 EMD62389.1 - 0.043 13.3 0.2 0.077 12.5 0.2 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B PLA2_B PF01735.13 EMD62390.1 - 2.3e-26 92.0 0.0 3.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.15 EMD62392.1 - 7.5e-09 35.2 0.1 2.3e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD62392.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EMD62392.1 - 0.082 11.7 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Glyco_hydro_32N PF00251.15 EMD62393.1 - 2.3e-15 56.7 0.0 3.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD62393.1 - 9.4e-08 32.3 0.0 2.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Cullin PF00888.17 EMD62394.1 - 8.2e-200 665.2 20.0 1.2e-199 664.6 13.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMD62394.1 - 3.1e-28 97.3 7.0 6.5e-28 96.3 3.9 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Cupin_2 PF07883.6 EMD62395.1 - 1.4e-08 34.1 0.2 3e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMD62395.1 - 4.2e-06 26.2 0.0 6.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMD62395.1 - 4.3e-05 23.2 0.1 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMD62395.1 - 0.0035 16.7 0.1 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMD62395.1 - 0.0076 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.6 EMD62395.1 - 0.021 13.8 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Mit_KHE1 PF10173.4 EMD62396.1 - 2.4e-60 203.6 2.4 2.4e-60 203.6 1.7 2.2 2 1 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF2362 PF10154.4 EMD62396.1 - 0.015 13.9 1.2 0.021 13.5 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) LUC7 PF03194.10 EMD62396.1 - 0.028 13.9 4.2 4.7 6.6 2.8 2.2 2 0 0 2 2 2 0 LUC7 N_terminus Thioredoxin_2 PF13098.1 EMD62396.1 - 0.041 14.0 0.5 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain DUF3596 PF12167.3 EMD62396.1 - 0.064 12.8 0.3 4.4 6.9 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3596) MARVEL PF01284.18 EMD62397.1 - 7.5e-06 25.8 5.3 1e-05 25.3 3.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain NST1 PF13945.1 EMD62397.1 - 0.01 15.9 0.8 0.035 14.1 0.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator TatD_DNase PF01026.16 EMD62399.1 - 6.3e-30 104.2 0.0 1.3e-29 103.1 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase F-box-like PF12937.2 EMD62400.1 - 1.7e-08 34.0 0.0 4.9e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD62400.1 - 9.4e-07 28.3 0.0 2.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Chitin_bind_1 PF00187.14 EMD62401.1 - 0.091 12.7 0.9 0.091 12.7 0.6 2.0 2 0 0 2 2 2 0 Chitin recognition protein G-alpha PF00503.15 EMD62404.1 - 9.7e-129 429.4 0.1 1.2e-128 429.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMD62404.1 - 1.2e-15 57.1 1.7 6.5e-11 41.7 0.1 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD62404.1 - 7.8e-05 21.9 0.1 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EMD62404.1 - 0.0011 19.5 0.1 0.52 10.8 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EMD62404.1 - 0.055 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMD62404.1 - 0.056 12.8 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EMD62405.1 - 7.3e-73 244.9 0.0 8.8e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62405.1 - 8.9e-32 110.1 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD62405.1 - 2.2e-05 23.6 0.0 8.3e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD62405.1 - 0.00019 20.5 0.0 0.024 13.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EMD62405.1 - 0.00026 20.7 0.1 0.00097 18.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMD62405.1 - 0.019 14.3 0.1 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Avl9 PF09794.4 EMD62406.1 - 4.2e-142 473.1 0.0 6.4e-142 472.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EMD62406.1 - 4.1e-08 32.9 0.2 4.6e-05 23.0 0.1 2.5 1 1 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EMD62406.1 - 1.4e-05 24.5 8.1 0.00047 19.5 0.1 3.7 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 EMD62406.1 - 0.014 15.1 1.0 0.15 11.7 0.2 2.7 2 1 1 3 3 3 0 DENN (AEX-3) domain DUF2229 PF09989.4 EMD62406.1 - 1.2 8.5 3.1 2.4 7.5 2.1 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GAGA_bind PF06217.7 EMD62406.1 - 6.3 6.6 11.5 1.2 9.0 3.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Epimerase PF01370.16 EMD62407.1 - 1.7e-23 83.2 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD62407.1 - 1e-11 44.0 0.0 1.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD62407.1 - 2.2e-09 37.4 0.1 4.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMD62407.1 - 2.4e-08 33.2 0.0 3.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMD62407.1 - 2.7e-08 33.0 0.3 4e-06 25.9 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EMD62407.1 - 1.3e-07 31.4 0.0 6.8e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMD62407.1 - 2e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 EMD62407.1 - 0.00022 21.0 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 EMD62407.1 - 0.022 14.0 0.0 4.7 6.4 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Saccharop_dh PF03435.13 EMD62407.1 - 0.093 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMD62407.1 - 0.11 11.4 0.0 0.78 8.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein COesterase PF00135.23 EMD62408.1 - 8e-98 328.4 0.1 5.1e-89 299.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD62408.1 - 3.5e-10 39.8 0.0 1.4e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold C2 PF00168.25 EMD62409.1 - 3.2e-12 46.1 0.1 3.3e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 C2 domain Peptidase_C2 PF00648.16 EMD62410.1 - 4.4e-59 199.9 0.5 2.5e-40 138.3 0.1 3.2 4 0 0 4 4 4 2 Calpain family cysteine protease MIP-T3 PF10243.4 EMD62410.1 - 0.13 10.6 38.1 0.19 10.1 26.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 EMD62410.1 - 2.6 6.1 24.5 4.1 5.5 17.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIF_alpha PF05793.7 EMD62410.1 - 3.5 5.8 31.9 5.2 5.3 22.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP-gamma PF07074.7 EMD62410.1 - 5.3 6.5 9.7 10 5.6 6.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Prok-RING_2 PF14445.1 EMD62411.1 - 0.12 12.2 3.6 0.22 11.4 2.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-Sec23_Sec24 PF04810.10 EMD62411.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger C1_4 PF07975.7 EMD62411.1 - 0.28 11.2 8.7 6.2 6.9 6.0 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain C1_3 PF07649.7 EMD62411.1 - 0.28 11.2 6.9 0.56 10.2 4.8 1.5 1 0 0 1 1 1 0 C1-like domain FYVE_2 PF02318.11 EMD62411.1 - 0.29 11.0 7.1 0.55 10.1 4.9 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 EMD62411.1 - 0.3 10.8 8.1 11 5.7 5.6 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.19 EMD62411.1 - 0.4 10.6 6.2 0.71 9.8 4.3 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.11 EMD62411.1 - 0.57 9.8 9.7 0.1 12.2 3.8 1.8 2 0 0 2 2 2 0 HIT zinc finger PHD_2 PF13831.1 EMD62411.1 - 1.4 8.2 8.2 3.6 6.9 0.1 2.8 2 1 0 2 2 2 0 PHD-finger C1_2 PF03107.11 EMD62411.1 - 2.8 8.1 7.5 14 5.8 5.5 2.0 1 1 1 2 2 2 0 C1 domain Tnp_zf-ribbon_2 PF13842.1 EMD62411.1 - 3.4 8.1 10.4 12 6.3 6.9 2.0 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_2 PF13923.1 EMD62411.1 - 3.8 7.6 9.8 1.8 8.6 4.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pribosyltran_N PF13793.1 EMD62413.1 - 1.4e-41 140.8 0.0 4.5e-40 136.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMD62413.1 - 6.3e-33 114.0 0.1 2.8e-26 92.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMD62413.1 - 0.00017 21.3 0.1 0.0034 17.0 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Peroxidase_2 PF01328.12 EMD62414.1 - 6.4e-15 54.6 0.0 1.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 SNF2_N PF00176.18 EMD62415.1 - 2.1e-67 227.0 0.1 1e-66 224.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD62415.1 - 2.4e-15 56.1 0.0 1.3e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Acetyltransf_1 PF00583.19 EMD62415.1 - 3.9e-08 33.2 0.0 9.7e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HDA2-3 PF11496.3 EMD62415.1 - 7e-08 31.6 6.1 1.2e-07 30.9 0.0 2.9 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 AT_hook PF02178.14 EMD62415.1 - 0.004 16.6 10.5 0.59 9.9 0.3 2.8 2 0 0 2 2 2 2 AT hook motif ATG_C PF09333.6 EMD62416.1 - 0.032 14.3 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain DUF336 PF03928.9 EMD62418.1 - 4.3e-33 113.9 0.9 4.8e-33 113.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) PKD_channel PF08016.7 EMD62419.1 - 2e-08 33.0 23.1 3.4e-07 29.0 16.0 2.1 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.7 EMD62420.1 - 1.4e-37 127.9 0.0 3.1e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMD62420.1 - 6.4e-13 48.5 0.8 1.4e-12 47.5 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain FimP PF09766.4 EMD62420.1 - 0.06 12.4 0.1 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein PH_4 PF15404.1 EMD62422.1 - 5.7e-65 218.3 0.1 2e-64 216.5 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EMD62422.1 - 2.8e-22 77.9 0.2 6.9e-22 76.6 0.1 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EMD62422.1 - 3.9e-08 33.4 0.0 0.048 13.8 0.0 4.0 3 0 0 3 3 3 2 PH domain PH_6 PF15406.1 EMD62422.1 - 0.00025 21.0 0.0 0.079 13.0 0.0 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain p450 PF00067.17 EMD62423.1 - 3.2e-55 187.4 0.0 4.3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.1 EMD62424.1 - 2.6e-07 30.9 0.0 5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62424.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62424.1 - 0.00032 21.1 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD62424.1 - 0.033 14.6 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EMD62425.1 - 3.7e-20 71.8 0.0 1.3e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.14 EMD62426.1 - 3.4e-48 163.7 0.0 4.1e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD62426.1 - 2.7e-30 105.5 0.0 3.5e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMD62426.1 - 1.4e-18 66.7 0.1 7.5e-15 54.5 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EMD62426.1 - 3.5e-11 42.5 0.0 4.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMD62426.1 - 2.5e-08 34.1 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD62426.1 - 5.1e-06 25.5 0.4 9.8e-05 21.3 0.2 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMD62426.1 - 0.0045 16.2 0.1 0.015 14.5 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMD62426.1 - 0.016 15.1 0.1 0.084 12.7 0.0 2.3 2 1 0 2 2 2 0 short chain dehydrogenase DUF4090 PF13319.1 EMD62427.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) BTB PF00651.26 EMD62428.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Endostatin PF06482.6 EMD62429.1 - 0.07 12.5 1.4 0.11 11.8 1.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DDE_1 PF03184.14 EMD62431.1 - 3.2e-50 170.2 0.0 4.6e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMD62431.1 - 1e-08 34.8 0.0 3.8e-08 33.0 0.0 2.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD62431.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CFEM PF05730.6 EMD62432.1 - 6e-13 48.4 8.3 6e-13 48.4 5.8 1.7 2 0 0 2 2 2 1 CFEM domain DUF4118 PF13493.1 EMD62432.1 - 0.0047 17.0 7.0 0.0047 17.0 4.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4118) RabGAP-TBC PF00566.13 EMD62436.1 - 5.7e-29 101.1 0.0 7.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EMD62437.1 - 1.9e-67 227.5 0.0 3.6e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EMD62437.1 - 6e-08 32.1 0.0 3.8e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 CPSF A subunit region zf-C2H2 PF00096.21 EMD62438.1 - 0.00031 20.8 6.9 0.01 16.1 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD62438.1 - 0.0011 19.1 7.8 0.23 11.8 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD62438.1 - 0.025 14.7 0.5 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3505 PF12013.3 EMD62438.1 - 0.32 11.2 5.7 0.42 10.8 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) zf-H2C2_2 PF13465.1 EMD62438.1 - 2.7 8.4 10.0 0.29 11.5 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double domain DUF2470 PF10615.4 EMD62439.1 - 0.002 18.2 0.7 0.0045 17.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Fzo_mitofusin PF04799.8 EMD62439.1 - 0.0044 16.4 5.1 0.049 13.0 0.2 2.1 1 1 0 2 2 2 2 fzo-like conserved region HALZ PF02183.13 EMD62439.1 - 0.019 14.6 0.3 0.019 14.6 0.2 2.9 2 1 2 4 4 4 0 Homeobox associated leucine zipper Filament PF00038.16 EMD62439.1 - 0.059 12.8 9.5 0.08 12.4 6.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein Prp19 PF08606.6 EMD62439.1 - 0.094 12.4 3.1 0.11 12.3 0.6 2.1 2 1 0 2 2 2 0 Prp19/Pso4-like IncA PF04156.9 EMD62439.1 - 0.1 12.2 8.3 0.054 13.0 1.9 2.0 1 1 1 2 2 2 0 IncA protein HN PF00423.14 EMD62439.1 - 0.17 10.1 0.5 0.18 10.0 0.3 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase PEP-utilisers_N PF05524.8 EMD62439.1 - 0.36 10.6 8.2 3 7.6 0.6 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1664 PF07889.7 EMD62439.1 - 1.1 9.0 6.9 3.1 7.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.5 EMD62439.1 - 1.3 9.3 4.6 1.6 9.0 0.9 2.4 2 1 0 2 2 2 0 Tup N-terminal Mnd1 PF03962.10 EMD62439.1 - 2.2 7.8 8.3 3.2 7.3 5.8 1.3 1 0 0 1 1 1 0 Mnd1 family COG2 PF06148.6 EMD62439.1 - 2.5 7.9 6.7 0.6 9.9 1.3 2.0 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 EMD62439.1 - 4 6.2 8.4 7.6 5.3 4.7 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EMD62439.1 - 4.4 7.6 8.2 3.4 8.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) OmpH PF03938.9 EMD62439.1 - 4.9 7.0 12.4 48 3.8 8.7 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EMD62439.1 - 7.6 5.3 9.4 10 4.9 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.3 EMD62439.1 - 9.7 6.6 13.4 7.9 6.9 4.2 2.1 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4246 PF14033.1 EMD62440.1 - 0.0049 15.5 4.3 0.0055 15.3 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) ING PF12998.2 EMD62440.1 - 0.0071 16.6 9.5 0.0071 16.6 6.6 2.5 1 1 2 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding YlqD PF11068.3 EMD62440.1 - 0.029 14.3 16.0 0.093 12.7 8.4 2.3 1 1 1 2 2 2 0 YlqD protein Sp38 PF07354.7 EMD62440.1 - 0.095 11.3 1.4 0.12 10.9 0.9 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) DUF3492 PF11997.3 EMD62440.1 - 0.13 11.7 4.2 0.18 11.2 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) DASH_Dam1 PF08653.5 EMD62440.1 - 0.15 11.8 0.9 20 5.0 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 TrbM PF07424.6 EMD62440.1 - 0.23 11.4 3.2 0.31 10.9 1.6 1.6 1 1 1 2 2 2 0 TrbM DUF948 PF06103.6 EMD62440.1 - 0.28 11.0 8.2 1.6 8.6 0.3 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 EMD62440.1 - 0.46 10.0 8.1 0.32 10.4 2.1 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBPIP PF07106.8 EMD62440.1 - 0.99 8.9 14.9 0.13 11.7 6.5 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Calpain_III PF01067.17 EMD62440.1 - 1 8.9 4.1 2.2 7.8 0.6 2.1 1 1 1 2 2 2 0 Calpain large subunit, domain III DUF2937 PF11157.3 EMD62440.1 - 1.5 8.1 10.3 0.12 11.6 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF342 PF03961.8 EMD62440.1 - 1.8 6.8 11.9 0.52 8.6 5.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mod_r PF07200.8 EMD62440.1 - 1.9 8.4 20.2 0.11 12.3 7.5 2.8 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 EMD62440.1 - 3.6 7.6 10.7 3.5 7.6 1.0 3.2 2 1 0 3 3 3 0 bZIP transcription factor IncA PF04156.9 EMD62440.1 - 9.1 5.8 29.0 1.9 8.0 10.0 2.2 1 1 1 2 2 2 0 IncA protein Ank_2 PF12796.2 EMD62441.1 - 6.4e-29 100.1 0.0 2e-16 60.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD62441.1 - 8.6e-25 86.2 0.5 9.8e-12 44.7 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD62441.1 - 1.5e-23 82.6 0.1 1.5e-14 54.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD62441.1 - 1.8e-19 68.4 0.0 5.3e-07 29.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD62441.1 - 9.3e-19 65.6 0.0 3.1e-07 29.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat PPR_3 PF13812.1 EMD62441.1 - 0.018 15.3 0.0 15 6.1 0.0 2.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMD62442.1 - 2.6e-21 75.3 0.1 3.3e-06 26.9 0.0 5.5 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EMD62442.1 - 2.1e-20 71.2 0.5 0.0022 18.1 0.0 9.8 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 EMD62442.1 - 5.8e-18 63.5 0.5 0.0075 16.1 0.1 8.4 8 0 0 8 8 8 4 PPR repeat TPR_14 PF13428.1 EMD62442.1 - 0.00018 21.8 15.0 2.3 9.0 0.1 9.0 9 2 2 11 11 11 1 Tetratricopeptide repeat PPR_1 PF12854.2 EMD62442.1 - 0.0011 18.4 1.4 12 5.4 0.1 5.0 5 0 0 5 5 5 1 PPR repeat SPOB_a PF14689.1 EMD62442.1 - 0.012 15.1 0.9 0.29 10.7 0.1 3.2 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_11 PF13414.1 EMD62442.1 - 0.013 15.1 0.1 2.4 7.8 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 EMD62442.1 - 0.072 13.0 1.4 24 5.1 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD62442.1 - 0.57 9.8 4.0 14 5.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GATA PF00320.22 EMD62444.1 - 5.1e-15 54.5 3.0 9e-15 53.7 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger EzrA PF06160.7 EMD62444.1 - 0.0083 14.3 1.5 0.011 13.9 1.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA IncA PF04156.9 EMD62444.1 - 0.019 14.5 3.3 0.028 13.9 2.3 1.2 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EMD62444.1 - 0.019 14.1 9.7 0.026 13.7 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TF_Zn_Ribbon PF08271.7 EMD62444.1 - 0.021 14.1 0.4 0.035 13.4 0.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding CDC37_N PF03234.9 EMD62444.1 - 0.029 14.6 1.6 0.042 14.1 1.1 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Macoilin PF09726.4 EMD62444.1 - 0.031 12.5 4.6 0.044 12.0 3.2 1.1 1 0 0 1 1 1 0 Transmembrane protein K167R PF08065.7 EMD62444.1 - 0.055 13.5 3.2 0.1 12.6 2.2 1.3 1 0 0 1 1 1 0 K167R (NUC007) repeat Nsp1_C PF05064.8 EMD62444.1 - 0.085 12.5 2.0 0.13 11.8 1.4 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region APG6 PF04111.7 EMD62444.1 - 0.087 11.8 6.0 0.13 11.2 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CASP_C PF08172.7 EMD62444.1 - 0.61 9.0 7.4 0.47 9.4 3.7 1.7 1 1 0 1 1 1 0 CASP C terminal DUF607 PF04678.8 EMD62444.1 - 0.77 9.6 2.8 1.1 9.0 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF904 PF06005.7 EMD62444.1 - 5.8 7.2 10.1 8 6.8 5.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) ATP-synt_C PF00137.16 EMD62445.1 - 1.2e-17 63.5 10.5 1.2e-17 63.5 7.3 2.5 2 1 0 2 2 2 2 ATP synthase subunit C MC1 PF05854.6 EMD62445.1 - 0.21 11.6 1.0 0.29 11.1 0.7 1.3 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 ELYS PF13934.1 EMD62446.1 - 0.0033 17.2 1.7 0.35 10.5 0.1 2.1 1 1 1 2 2 2 2 Nuclear pore complex assembly Imm29 PF15575.1 EMD62446.1 - 0.0047 16.5 7.3 0.037 13.6 0.6 2.9 1 1 2 3 3 3 2 Immunity protein 29 XPC-binding PF09280.6 EMD62446.1 - 0.02 14.3 6.5 23 4.5 0.1 5.5 5 1 1 6 6 6 0 XPC-binding domain TraH PF06122.6 EMD62446.1 - 0.031 13.0 10.0 0.018 13.8 1.6 2.2 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein FCD PF07729.7 EMD62446.1 - 0.039 14.2 32.9 1 9.7 0.3 6.0 2 2 3 6 6 6 0 FCD domain Reductase_C PF14759.1 EMD62446.1 - 0.075 13.3 14.6 3.9 7.8 0.3 5.0 2 2 3 5 5 5 0 Reductase C-terminal ECH_C PF13766.1 EMD62446.1 - 0.32 11.1 17.3 15 5.7 0.1 5.3 1 1 4 5 5 5 0 2-enoyl-CoA Hydratase C-terminal region AATF-Che1 PF13339.1 EMD62446.1 - 0.49 10.5 6.8 2.6 8.1 0.8 2.2 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor PDGLE PF13190.1 EMD62446.1 - 0.57 9.9 6.9 3.4 7.4 0.2 3.8 3 2 1 4 4 4 0 PDGLE domain Pex19 PF04614.7 EMD62446.1 - 0.59 9.7 11.6 0.97 8.9 1.9 2.5 2 1 0 2 2 2 0 Pex19 protein family NifQ PF04891.7 EMD62446.1 - 0.96 9.5 10.8 4.8 7.3 0.6 2.9 2 2 1 3 3 3 0 NifQ TipAS PF07739.8 EMD62446.1 - 1.1 9.6 22.3 0.068 13.4 1.3 5.0 1 1 4 5 5 5 0 TipAS antibiotic-recognition domain HRDC PF00570.18 EMD62446.1 - 1.5 8.6 6.1 12 5.6 0.0 4.2 5 0 0 5 5 5 0 HRDC domain HemY_N PF07219.8 EMD62446.1 - 1.6 8.2 23.3 0.8 9.2 5.6 3.7 2 2 1 3 3 3 0 HemY protein N-terminus ThylakoidFormat PF11264.3 EMD62446.1 - 3.2 7.3 9.4 6.9 6.2 0.4 2.7 2 1 0 2 2 2 0 Thylakoid formation protein CHASE3 PF05227.8 EMD62446.1 - 4.6 6.9 17.8 4.5 6.9 4.1 2.3 2 0 0 2 2 2 0 CHASE3 domain MFS_1 PF07690.11 EMD62447.1 - 5.9e-37 127.1 39.0 5.9e-37 127.1 27.0 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62447.1 - 1.9e-13 49.8 8.7 1.9e-13 49.8 6.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3382 PF11862.3 EMD62447.1 - 0.00028 20.7 4.3 0.24 11.3 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF3382) OATP PF03137.15 EMD62447.1 - 0.21 9.5 4.4 0.16 9.9 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GTP_EFTU PF00009.22 EMD62448.1 - 7.3e-33 113.5 0.0 3.7e-32 111.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMD62448.1 - 4.3e-16 58.7 0.1 1.3e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMD62448.1 - 2.7e-11 43.4 6.9 3.4e-10 39.8 0.0 3.5 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD62448.1 - 1.2e-06 28.5 0.3 5.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrkA_C PF02080.16 EMD62448.1 - 0.00046 19.7 0.6 1.1 8.9 0.0 3.4 3 0 0 3 3 3 2 TrkA-C domain GTP_EFTU_D4 PF14578.1 EMD62448.1 - 0.0021 17.6 0.0 0.0085 15.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EMD62448.1 - 0.0061 16.1 1.5 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Chitin_synth_2 PF03142.10 EMD62449.1 - 1.4e-245 815.6 0.2 1.9e-245 815.3 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMD62449.1 - 2.5e-166 554.6 0.0 3.3e-166 554.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EMD62449.1 - 1.1e-19 70.0 0.4 2.4e-13 49.6 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EMD62449.1 - 1.1e-17 63.4 1.3 4.6e-17 61.5 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EMD62449.1 - 1.5e-13 50.8 5.2 1.5e-13 50.8 3.6 2.0 2 1 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD62449.1 - 4.1e-12 46.3 0.1 2.2e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD62449.1 - 0.00095 18.8 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_22 PF13401.1 EMD62449.1 - 0.0024 18.0 0.0 0.0075 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMD62449.1 - 0.045 12.9 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMD62449.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF2592 PF10766.4 EMD62449.1 - 0.19 11.1 1.9 0.6 9.4 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 EMD62450.1 - 9.6e-233 773.3 0.1 1.3e-232 772.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMD62450.1 - 9e-46 156.2 0.0 9.7e-44 149.5 0.0 3.0 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EMD62450.1 - 5.5e-17 62.1 3.5 5.5e-17 62.1 2.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD62450.1 - 6.1e-16 58.9 0.0 3.1e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EMD62450.1 - 9.6e-16 57.3 0.0 6e-09 35.5 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EMD62450.1 - 5.5e-13 48.4 0.8 3.9e-12 45.7 0.3 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EMD62450.1 - 4.5e-06 26.0 0.0 1.8e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD62450.1 - 0.00055 19.6 0.0 0.014 15.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 End3 PF12761.2 EMD62451.1 - 6.3e-70 234.7 0.1 8.2e-70 234.4 0.1 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EMD62451.1 - 3.2e-49 164.9 0.0 3.8e-48 161.5 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMD62451.1 - 1.9e-08 33.0 1.0 1.7e-07 30.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMD62451.1 - 5e-08 32.4 1.6 1.8e-06 27.4 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 EMD62451.1 - 1.1e-05 25.4 1.6 5.5e-05 23.2 0.0 2.8 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EMD62451.1 - 0.00033 20.2 0.3 0.00033 20.2 0.2 2.7 3 0 0 3 3 2 1 EF-hand domain EF-hand_5 PF13202.1 EMD62451.1 - 0.00049 19.3 0.8 0.0012 18.1 0.1 2.1 2 0 0 2 2 2 1 EF hand Med9 PF07544.8 EMD62451.1 - 0.0048 16.6 0.3 0.0048 16.6 0.2 2.8 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 AKNA PF12443.3 EMD62451.1 - 0.028 14.4 1.0 0.028 14.4 0.7 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor TSC22 PF01166.13 EMD62451.1 - 0.075 13.0 8.9 1.7 8.6 0.6 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Filament PF00038.16 EMD62451.1 - 0.12 11.8 7.5 0.18 11.2 5.2 1.3 1 0 0 1 1 1 0 Intermediate filament protein COG2 PF06148.6 EMD62451.1 - 0.28 11.0 4.6 2.2 8.1 0.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 EMD62451.1 - 0.92 9.2 5.9 2.7 7.7 0.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EMD62451.1 - 1 8.8 5.5 5.4 6.4 0.1 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Mnd1 PF03962.10 EMD62451.1 - 1.2 8.7 6.4 5.5 6.5 4.4 1.8 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EMD62451.1 - 2.8 7.4 6.7 12 5.4 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 EMD62451.1 - 3.1 6.6 9.0 6.9 5.5 6.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EMD62451.1 - 9.2 5.8 8.1 1e+02 2.4 6.0 1.9 1 1 0 1 1 1 0 IncA protein DAO PF01266.19 EMD62452.1 - 8.7e-53 179.4 0.1 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD62452.1 - 5.1e-06 26.6 0.0 0.00014 22.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD62452.1 - 0.00019 21.3 0.1 0.00043 20.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD62452.1 - 0.0054 16.6 0.3 0.2 11.5 0.1 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62452.1 - 0.02 13.8 0.0 0.22 10.4 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMD62452.1 - 0.034 12.9 0.4 0.082 11.7 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain NUDIX PF00293.23 EMD62453.1 - 2.9e-14 52.8 0.1 1.1e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Chitin_synth_2 PF03142.10 EMD62454.1 - 3.5e-24 85.0 0.6 3.5e-24 85.0 0.4 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMD62454.1 - 9e-18 64.6 1.3 9e-18 64.6 0.9 2.4 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD62454.1 - 1.1e-17 64.6 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD62454.1 - 0.0015 18.2 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 MIF4G PF02854.14 EMD62456.1 - 2.4e-60 203.5 0.0 3.4e-28 98.4 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EMD62456.1 - 7.1e-54 182.1 16.1 7.1e-54 182.1 11.1 3.4 5 0 0 5 5 5 1 Up-frameshift suppressor 2 FliD_C PF07195.7 EMD62456.1 - 0.027 13.7 1.9 0.074 12.3 0.2 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus His_Phos_2 PF00328.17 EMD62457.1 - 1.5e-20 73.8 0.0 1.9e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EMD62457.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HTH_Tnp_Tc5 PF03221.11 EMD62458.1 - 1e-11 44.4 0.7 1.2e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Ribosomal_S13_N PF08069.7 EMD62458.1 - 0.062 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Drf_GBD PF06371.8 EMD62458.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain TPK_catalytic PF04263.11 EMD62460.1 - 5.1e-24 84.2 0.0 7.3e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EMD62460.1 - 7.9e-17 60.7 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SKN1 PF03935.10 EMD62463.1 - 9e-221 733.3 2.6 1e-220 733.1 1.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Autotrns_rpt PF12951.2 EMD62463.1 - 2.3 8.0 7.2 0.63 9.7 2.4 2.0 2 0 0 2 2 2 0 Autotransporter-associated beta strand repeat DUF3636 PF12331.3 EMD62464.1 - 3.5e-46 156.4 0.1 7.5e-46 155.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Transposase_22 PF02994.9 EMD62464.1 - 0.0095 14.4 0.4 0.015 13.8 0.2 1.2 1 0 0 1 1 1 1 L1 transposable element MAD PF05557.8 EMD62464.1 - 0.31 9.1 7.2 0.43 8.6 5.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein CTP_transf_1 PF01148.15 EMD62465.1 - 3.9e-81 272.5 28.4 4.9e-81 272.2 19.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PPR_2 PF13041.1 EMD62466.1 - 2.2e-21 75.5 1.0 0.00013 21.8 0.1 7.9 4 2 3 7 7 7 5 PPR repeat family PPR_3 PF13812.1 EMD62466.1 - 1e-17 62.8 11.5 0.0036 17.4 0.0 9.6 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 EMD62466.1 - 5.9e-12 44.7 11.7 0.041 13.8 0.1 9.3 10 0 0 10 10 10 3 PPR repeat TPR_14 PF13428.1 EMD62466.1 - 4.8e-05 23.6 0.8 3 8.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD62466.1 - 0.00059 19.4 0.5 0.58 10.0 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD62466.1 - 0.00065 19.5 1.4 4.8 7.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD62466.1 - 0.0034 17.2 0.4 7.3 6.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 EMD62466.1 - 0.1 12.0 1.8 42 3.7 0.2 4.9 5 1 0 5 5 5 0 PPR repeat TPR_1 PF00515.23 EMD62466.1 - 0.13 11.9 1.1 10 5.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMD62467.1 - 7.9e-97 324.6 20.0 9.1e-97 324.4 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62467.1 - 1.9e-23 82.7 21.1 1.9e-23 82.7 14.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMD62467.1 - 0.00039 18.9 1.1 0.00039 18.9 0.7 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein NmrA PF05368.8 EMD62469.1 - 7.1e-18 64.7 0.0 9.5e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD62469.1 - 3.5e-14 53.2 0.0 6.4e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD62469.1 - 2.2e-08 33.8 0.1 5.4e-06 26.0 0.0 2.3 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD62469.1 - 0.029 13.0 0.0 0.05 12.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD62469.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMD62469.1 - 0.035 12.9 0.1 0.082 11.7 0.0 1.7 2 1 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.13 EMD62469.1 - 0.045 13.4 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMD62469.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 EMD62469.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMD62469.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus bZIP_1 PF00170.16 EMD62470.1 - 2.8e-10 39.9 7.8 4.5e-10 39.3 5.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD62470.1 - 4.5e-05 23.1 12.3 4.5e-05 23.1 8.5 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD62470.1 - 0.0021 18.2 7.5 0.0052 17.0 5.2 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Sec2p PF06428.6 EMD62470.1 - 0.011 15.5 1.6 0.019 14.8 1.1 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Neisseria_TspB PF05616.8 EMD62470.1 - 2.6 6.3 6.4 3.6 5.8 4.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Zn_clus PF00172.13 EMD62471.1 - 1.2e-07 31.5 7.4 2.5e-07 30.4 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD62471.1 - 9.9e-06 24.3 0.3 1.5e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DSPc PF00782.15 EMD62472.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD62472.1 - 7.4e-05 22.1 0.0 0.00027 20.3 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMD62472.1 - 0.0035 17.4 0.0 0.014 15.4 0.0 2.0 1 1 1 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMD62472.1 - 0.0079 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family PTEN_C2 PF10409.4 EMD62472.1 - 0.0086 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein CDKN3 PF05706.7 EMD62472.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RNA_pol_Rpc4 PF05132.9 EMD62472.1 - 3.4 7.6 6.5 0.24 11.3 0.1 2.2 2 1 0 2 2 2 0 RNA polymerase III RPC4 AAA PF00004.24 EMD62473.1 - 9.1e-16 58.2 0.0 3.1e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD62473.1 - 0.00015 22.6 0.1 0.0033 18.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EMD62473.1 - 0.0012 19.0 1.0 0.014 15.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EMD62473.1 - 0.0017 18.3 2.0 0.0026 17.7 0.0 2.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMD62473.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMD62473.1 - 0.04 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMD62473.1 - 0.083 12.2 0.7 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 EMD62473.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMD62473.1 - 0.1 12.9 2.7 0.13 12.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 EMD62474.1 - 7.3e-24 84.0 0.1 1.1e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62474.1 - 4.8e-08 32.7 10.2 1e-07 31.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_7 PF00840.15 EMD62476.1 - 1.1e-136 455.6 11.9 1.3e-136 455.4 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF1754 PF08555.5 EMD62477.1 - 0.32 11.5 3.2 0.42 11.2 2.2 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CAF-1_p150 PF11600.3 EMD62477.1 - 1.3 8.3 11.5 1.5 8.1 8.0 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1675 PF07897.6 EMD62477.1 - 1.7 8.4 6.0 1.8 8.3 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MGC-24 PF05283.6 EMD62477.1 - 6.7 6.4 10.5 8.2 6.1 7.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) AlaDh_PNT_N PF05222.10 EMD62478.1 - 8.3e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EMD62478.1 - 2.2e-11 43.5 0.0 3.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Head_binding PF09008.5 EMD62478.1 - 0.16 12.0 0.1 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Head binding Sulfate_transp PF00916.15 EMD62479.1 - 3.1e-54 183.8 3.5 6.6e-54 182.8 2.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMD62479.1 - 1.2e-30 105.0 1.8 5.5e-30 102.8 1.2 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMD62479.1 - 1.6e-18 66.2 0.0 2.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMD62479.1 - 1.8e-06 27.8 0.0 5.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sugar_tr PF00083.19 EMD62480.1 - 1.8e-37 128.9 22.3 4.8e-37 127.5 15.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62480.1 - 6.4e-36 123.7 28.1 6.6e-30 104.0 5.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMD62480.1 - 0.014 13.9 21.4 0.032 12.7 3.4 2.3 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Glyco_hydro_61 PF03443.9 EMD62481.1 - 1.4e-55 188.4 0.2 1.6e-55 188.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF779 PF05610.6 EMD62481.1 - 0.087 12.8 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF779) DAO PF01266.19 EMD62482.1 - 9e-32 110.3 0.0 2.2e-31 109.0 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62482.1 - 0.0036 17.3 0.0 0.0087 16.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD62482.1 - 0.005 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD62482.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62482.1 - 0.15 10.9 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M6 PF05547.6 EMD62484.1 - 8.6e-07 27.3 0.2 0.0052 14.8 0.5 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 La PF05383.12 EMD62485.1 - 6.3e-14 51.5 0.0 1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EMD62485.1 - 1.4e-05 24.6 0.1 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD62485.1 - 0.0034 17.3 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 EMD62486.1 - 1.4e-15 56.4 0.0 2.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain HBS1_N PF08938.5 EMD62486.1 - 0.015 15.4 3.4 0.18 11.9 0.1 2.4 2 0 0 2 2 2 0 HBS1 N-terminus S4_2 PF13275.1 EMD62486.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain Phage_GP20 PF06810.6 EMD62486.1 - 0.56 9.6 6.6 1 8.8 2.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 CENP-Q PF13094.1 EMD62487.1 - 0.037 14.0 2.3 0.044 13.8 0.1 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LSM PF01423.17 EMD62488.1 - 2.6e-14 52.5 0.0 3.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD62488.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.1 EMD62488.1 - 2.3 8.5 8.9 4.1 7.7 6.2 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein MFS_1 PF07690.11 EMD62489.1 - 7.2e-35 120.3 25.9 9.5e-35 119.9 17.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 EMD62489.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.6 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding ADH_zinc_N PF00107.21 EMD62490.1 - 2.9e-21 75.3 0.4 4.5e-21 74.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD62490.1 - 1.1e-07 32.8 0.1 2.4e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD62490.1 - 0.0079 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMD62490.1 - 0.026 14.5 0.1 0.056 13.4 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding GFA PF04828.9 EMD62491.1 - 4.9e-13 48.8 0.7 1e-12 47.7 0.5 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RRM_6 PF14259.1 EMD62492.1 - 6.5e-09 35.6 0.0 1.9e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD62492.1 - 1.1e-07 31.4 0.0 2.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD62492.1 - 4.2e-06 26.5 0.0 7.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EMD62492.1 - 0.00014 21.8 0.3 0.0095 16.0 0.0 2.3 2 0 0 2 2 2 1 PWI domain RRM_3 PF08777.6 EMD62492.1 - 0.0016 18.2 6.9 0.0031 17.3 0.3 3.1 2 1 1 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMD62492.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.1 EMD62492.1 - 0.011 14.8 0.0 0.025 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Toxin_39 PF15500.1 EMD62492.1 - 0.031 14.3 2.7 0.058 13.5 1.3 1.9 1 1 0 1 1 1 0 Putative RNase-like toxin zf-CCCH PF00642.19 EMD62492.1 - 0.037 13.7 1.4 0.073 12.7 1.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Selenoprotein_S PF06936.6 EMD62492.1 - 0.75 9.2 8.4 0.035 13.6 1.8 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) Atg14 PF10186.4 EMD62492.1 - 7.1 5.4 6.1 11 4.8 4.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GTP_EFTU PF00009.22 EMD62493.1 - 1.1e-62 210.7 0.2 1.6e-62 210.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMD62493.1 - 3.4e-38 129.8 0.0 8.6e-38 128.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMD62493.1 - 1.4e-20 72.8 0.0 7.8e-20 70.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD62493.1 - 2.9e-13 49.7 0.7 4.3e-12 45.9 0.0 3.2 4 0 0 4 4 4 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMD62493.1 - 1.1e-10 41.1 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EMD62493.1 - 1.1e-05 25.3 0.2 2.3e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cyclin_N PF00134.18 EMD62494.1 - 1.2e-10 40.9 0.1 4.4e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain p450 PF00067.17 EMD62495.1 - 1.5e-49 168.7 0.0 2.2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MutL_C PF08676.6 EMD62497.1 - 5.4e-22 77.9 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EMD62497.1 - 1.2e-19 69.9 0.4 1.2e-18 66.6 0.1 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMD62497.1 - 8.2e-14 51.4 0.0 2.8e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMD62497.1 - 2.9e-13 49.5 0.0 6.5e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF664 PF04978.7 EMD62497.1 - 0.044 14.0 3.4 0.14 12.3 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF664) Spt5_N PF11942.3 EMD62497.1 - 0.24 12.0 15.4 0.45 11.1 2.6 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EMD62497.1 - 4 6.9 12.7 0.24 10.9 0.6 2.6 2 0 0 2 2 2 0 Nucleoplasmin Iso_dh PF00180.15 EMD62499.1 - 2.3e-99 332.6 0.0 2.9e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S26 PF10502.4 EMD62500.1 - 2.5e-06 27.0 0.0 1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EMD62500.1 - 4.2e-06 26.3 0.8 2e-05 24.1 0.6 2.0 1 1 0 1 1 1 1 Peptidase S24-like Iso_dh PF00180.15 EMD62501.1 - 5.2e-64 216.3 0.0 6.2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GLTP PF08718.6 EMD62502.1 - 4.5e-46 156.5 0.0 6e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Methyltransf_32 PF13679.1 EMD62503.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMD62503.1 - 0.079 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pirin PF02678.11 EMD62504.1 - 2.7e-27 94.7 0.6 4.5e-27 94.0 0.4 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EMD62504.1 - 0.00029 20.2 1.8 0.0035 16.8 0.1 2.7 2 1 1 3 3 3 1 Cupin domain Defensin_beta_2 PF13841.1 EMD62505.1 - 0.12 12.7 3.9 0.14 12.4 0.9 2.4 2 0 0 2 2 2 0 Beta defensin Ribosomal_L22e PF01776.12 EMD62505.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L22e protein family DUF4231 PF14015.1 EMD62505.1 - 6.7 6.7 12.0 1.3 9.0 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Baculo_PEP_C PF04513.7 EMD62506.1 - 0.056 13.2 0.1 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Perilipin PF03036.11 EMD62506.1 - 0.067 12.0 1.1 1 8.0 0.1 2.0 1 1 1 2 2 2 0 Perilipin family DUF883 PF05957.8 EMD62506.1 - 0.082 13.3 4.9 0.19 12.1 2.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.9 EMD62506.1 - 0.092 12.1 1.7 0.14 11.5 0.1 1.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Tape_meas_lam_C PF09718.5 EMD62506.1 - 0.2 11.5 11.2 1.5 8.8 3.1 2.5 1 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2523 PF10734.4 EMD62506.1 - 0.27 11.4 9.4 2.6 8.3 0.2 3.5 1 1 0 3 3 3 0 Protein of unknown function (DUF2523) Ferric_reduct PF01794.14 EMD62507.1 - 3.7e-18 65.8 6.9 3.7e-18 65.8 4.7 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD62507.1 - 2.1e-10 40.7 0.0 1.1e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD62507.1 - 4.3e-10 39.4 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMD62507.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4381 PF14316.1 EMD62507.1 - 0.1 12.6 0.3 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2615 PF11027.3 EMD62507.1 - 0.15 12.0 0.0 0.71 9.8 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF373 PF04123.8 EMD62507.1 - 0.63 9.0 4.6 0.64 8.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) FA_hydroxylase PF04116.8 EMD62508.1 - 3.4e-16 59.6 23.1 9.5e-16 58.2 15.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SLAC1 PF03595.12 EMD62508.1 - 0.017 13.7 7.2 0.073 11.7 4.7 2.0 1 1 1 2 2 2 0 Voltage-dependent anion channel GMC_oxred_N PF00732.14 EMD62510.1 - 5.8e-44 150.4 0.0 8.1e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD62510.1 - 9.5e-39 132.9 0.0 1.6e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD62510.1 - 0.00099 18.0 0.1 0.0094 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD62510.1 - 0.0029 16.5 0.4 0.4 9.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EMD62510.1 - 0.2 12.0 1.4 0.43 11.0 1.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62510.1 - 0.2 10.5 0.3 0.35 9.7 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein EthD PF07110.6 EMD62511.1 - 2.4e-12 47.6 0.0 3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 EthD domain Glyco_hydro_31 PF01055.21 EMD62513.1 - 1.2e-111 373.6 3.8 1.5e-111 373.4 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD62513.1 - 2.2e-15 56.2 0.1 1e-13 50.9 0.0 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 EMD62514.1 - 6.4e-82 275.5 24.2 7.4e-82 275.3 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62514.1 - 1.1e-25 90.1 27.4 1.1e-25 90.1 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD62514.1 - 5.8e-06 24.7 2.2 5.8e-06 24.7 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.3 EMD62514.1 - 0.14 12.0 5.5 1.4 8.7 0.6 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) AAA PF00004.24 EMD62515.1 - 2.5e-11 43.9 0.0 5.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMD62515.1 - 1.7e-05 24.5 0.2 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 EMD62515.1 - 2.3e-05 23.2 0.2 9.6e-05 21.2 0.0 2.0 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EMD62515.1 - 2.7e-05 23.3 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD62515.1 - 7.5e-05 22.8 0.0 0.00029 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD62515.1 - 0.00013 21.7 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMD62515.1 - 0.0018 18.1 0.2 0.0065 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD62515.1 - 0.0037 18.0 0.0 0.019 15.7 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMD62515.1 - 0.004 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD62515.1 - 0.008 16.1 1.1 0.028 14.4 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.10 EMD62515.1 - 0.013 15.1 0.2 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 EMD62515.1 - 0.016 14.9 0.0 1.2 8.8 0.0 2.6 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EMD62515.1 - 0.022 13.9 0.3 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EMD62515.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 EMD62515.1 - 0.65 10.3 4.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 ABC transporter adh_short PF00106.20 EMD62516.1 - 7.4e-23 81.2 0.0 1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD62516.1 - 6.9e-12 45.3 0.0 9.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD62516.1 - 5.6e-09 36.1 0.0 8.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD62516.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD62516.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMD62516.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Alpha-amylase PF00128.19 EMD62517.1 - 2.6e-64 217.6 0.7 8.8e-64 215.8 0.5 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 EMD62517.1 - 1.5e-30 104.6 0.6 3.6e-30 103.4 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 EMD62517.1 - 3.9e-06 26.8 0.2 1.3e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 EMD62518.1 - 1.8e-34 117.1 1.2 3.7e-34 116.2 0.8 1.5 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 EMD62518.1 - 5.3e-09 36.6 0.8 3.4e-06 27.4 0.0 2.7 1 1 0 2 2 2 2 Chitin binding domain Glyco_hydro_61 PF03443.9 EMD62518.1 - 0.00047 20.0 0.1 0.039 13.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Hamartin PF04388.7 EMD62518.1 - 3 6.4 8.7 3.9 6.0 6.0 1.1 1 0 0 1 1 1 0 Hamartin protein Peptidase_M14 PF00246.19 EMD62521.1 - 1.9e-66 224.5 0.2 4.9e-66 223.1 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Nucleoplasmin PF03066.10 EMD62522.1 - 0.011 15.2 1.9 0.011 15.2 1.3 1.6 2 0 0 2 2 2 0 Nucleoplasmin Saw1 PF11561.3 EMD62522.1 - 0.048 13.0 0.9 0.094 12.0 0.6 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Cytochrome-c551 PF10643.4 EMD62522.1 - 0.17 11.1 0.5 0.29 10.3 0.3 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Ribosomal_60s PF00428.14 EMD62522.1 - 0.26 11.7 13.5 0.95 9.9 5.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sigma70_r1_1 PF03979.9 EMD62522.1 - 0.98 9.4 0.0 0.98 9.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 VID27 PF08553.5 EMD62522.1 - 1.8 6.6 7.8 2.9 5.9 5.4 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein PBP1_TM PF14812.1 EMD62522.1 - 4.3 7.7 10.1 2 8.7 2.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF605 PF04652.11 EMD62522.1 - 8.3 5.6 21.1 1.6 8.0 11.3 2.0 2 0 0 2 2 2 0 Vta1 like Lectin_C PF00059.16 EMD62523.1 - 0.0042 17.7 0.1 0.033 14.8 0.1 2.2 2 0 0 2 2 2 1 Lectin C-type domain Myb_DNA-binding PF00249.26 EMD62524.1 - 1.4e-24 85.8 3.2 9.8e-14 51.1 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD62524.1 - 3.2e-17 62.3 2.9 8.3e-12 45.0 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EMD62524.1 - 0.024 14.3 0.1 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.3 EMD62524.1 - 0.055 13.4 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EMD62524.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 PAT1 PF09770.4 EMD62527.1 - 7.1 4.7 15.7 8.8 4.4 10.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.4 EMD62529.1 - 0.069 11.2 0.3 0.074 11.1 0.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2034 PF10356.4 EMD62530.1 - 3e-25 88.4 0.0 9.5e-15 54.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EMD62530.1 - 1.9e-07 30.9 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EMD62531.1 - 1.1e-38 132.4 5.9 1.2e-38 132.2 4.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GOLGA2L5 PF15070.1 EMD62531.1 - 0.00018 20.1 7.2 0.00023 19.8 5.0 1.2 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 TMCO5 PF14992.1 EMD62531.1 - 0.0029 16.7 1.4 0.0034 16.5 1.0 1.2 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 EMD62531.1 - 0.03 14.0 11.7 0.041 13.6 3.4 3.0 3 1 1 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EMD62531.1 - 0.035 13.6 0.7 0.035 13.6 0.5 1.7 2 0 0 2 2 2 0 IncA protein Complex1_LYR_2 PF13233.1 EMD62531.1 - 0.039 14.4 0.4 0.051 14.0 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DUF1515 PF07439.6 EMD62531.1 - 0.088 12.6 2.0 0.12 12.2 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Spore_III_AB PF09548.5 EMD62531.1 - 0.1 12.3 3.2 0.29 10.8 1.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.7 EMD62531.1 - 0.11 12.7 2.6 3.4 7.9 0.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 EMD62531.1 - 0.29 11.4 5.8 2.1 8.7 0.0 2.7 2 1 0 2 2 2 0 Snapin/Pallidin AAA_13 PF13166.1 EMD62531.1 - 0.57 8.5 3.9 2.3 6.5 2.6 1.9 1 1 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.2 EMD62531.1 - 0.63 9.3 5.8 1.1 8.6 1.7 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1342 PF07072.6 EMD62531.1 - 0.83 9.2 4.4 0.76 9.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) CtIP_N PF10482.4 EMD62531.1 - 0.91 9.3 6.2 0.17 11.7 1.8 1.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain V-SNARE PF05008.10 EMD62531.1 - 0.97 9.6 7.3 5.5 7.2 0.2 3.1 3 1 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus DUF3450 PF11932.3 EMD62531.1 - 1.1 8.4 5.4 1.2 8.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin PF02996.12 EMD62531.1 - 1.8 8.2 9.9 9.7 5.8 0.6 3.1 3 0 0 3 3 3 0 Prefoldin subunit APG6 PF04111.7 EMD62531.1 - 2.5 7.0 7.4 0.34 9.9 2.2 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EMD62531.1 - 2.6 7.9 9.2 7.7 6.4 6.3 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EMD62531.1 - 2.6 8.4 5.0 4.3 7.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4404 PF14357.1 EMD62531.1 - 3.7 8.0 8.4 0.65 10.4 1.1 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4404) ECM11 PF15463.1 EMD62531.1 - 5.2 7.3 8.2 0.96 9.7 2.8 1.9 2 1 0 2 2 2 0 Extracellular mutant protein 11 bZIP_1 PF00170.16 EMD62531.1 - 5.5 7.0 9.8 3 7.8 2.1 2.7 2 1 1 3 3 3 0 bZIP transcription factor DUF948 PF06103.6 EMD62531.1 - 7.1 6.5 7.0 11 5.9 0.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Serinc PF03348.10 EMD62533.1 - 3.7e-171 569.5 6.8 4.3e-171 569.3 4.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 EMD62534.1 - 1.5e-16 60.0 26.7 4.2e-16 58.6 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EMD62534.1 - 1.1e-15 57.6 5.2 2.3e-15 56.5 3.6 1.5 1 0 0 1 1 1 1 Nodulin-like Ribosomal_60s PF00428.14 EMD62536.1 - 0.27 11.6 17.5 0.23 11.8 10.6 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EMD62536.1 - 9.5 6.6 7.9 11 6.4 1.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec5 PF15469.1 EMD62537.1 - 1.1e-38 132.8 0.0 4.1e-38 130.9 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EMD62537.1 - 0.00045 20.0 0.0 0.0019 17.9 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Mito_carr PF00153.22 EMD62538.1 - 6.6e-59 195.6 0.7 2.9e-19 68.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Rho_N PF07498.7 EMD62539.1 - 0.014 15.1 0.3 0.04 13.6 0.2 1.8 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain zf-MYND PF01753.13 EMD62540.1 - 1.4e-10 40.8 15.7 2.3e-10 40.1 10.9 1.3 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 EMD62540.1 - 2.7e-08 34.0 0.0 0.00039 20.6 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD62540.1 - 0.00022 21.3 0.0 1.4 9.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD62540.1 - 0.0038 16.9 0.0 0.57 10.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMD62540.1 - 0.0073 16.4 0.0 4.6 7.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMD62540.1 - 0.09 13.3 0.0 3 8.4 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ecl1 PF12855.2 EMD62540.1 - 3.2 7.1 7.5 9.6 5.5 4.6 2.2 2 1 0 2 2 2 0 Life-span regulatory factor adh_short_C2 PF13561.1 EMD62541.1 - 6e-24 85.1 2.2 7e-24 84.9 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD62541.1 - 1.9e-18 66.9 6.8 2.5e-18 66.5 4.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD62541.1 - 3.4e-06 26.8 3.6 5.1e-06 26.2 2.5 1.2 1 0 0 1 1 1 1 KR domain DUF1462 PF07315.6 EMD62541.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) RA PF00788.18 EMD62541.1 - 0.068 13.6 0.0 0.54 10.7 0.0 2.0 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Cyclase PF04199.8 EMD62542.1 - 4.4e-15 55.7 0.0 6.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 EMD62543.1 - 4.3e-97 325.5 22.0 4.9e-97 325.3 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62543.1 - 3.5e-31 108.2 33.5 3.5e-24 85.1 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 EMD62544.1 - 2.4e-38 131.6 0.0 4.2e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydro_44 PF12891.2 EMD62544.1 - 0.23 10.9 2.3 0.4 10.1 1.1 1.7 1 1 1 2 2 2 0 Glycoside hydrolase family 44 Sulfotransfer_3 PF13469.1 EMD62545.1 - 0.00013 22.8 0.1 0.00021 22.2 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EMD62545.1 - 0.059 12.6 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain SET PF00856.23 EMD62546.1 - 8.8e-14 52.1 0.4 2.9e-13 50.4 0.0 2.0 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.1 EMD62546.1 - 0.045 13.6 0.3 0.094 12.6 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 EMD62547.1 - 1.4e-38 132.0 0.0 5.9e-38 130.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD62547.1 - 6.5e-23 81.0 0.0 1.4e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD62547.1 - 7.5e-19 67.7 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4236 PF14020.1 EMD62547.1 - 0.042 13.9 0.2 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Abhydrolase_4 PF08386.5 EMD62548.1 - 7.9e-19 67.4 0.0 1.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMD62548.1 - 2.9e-13 49.9 0.8 1.7e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD62548.1 - 6.7e-10 39.2 0.4 4.3e-08 33.3 0.3 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD62548.1 - 3e-06 27.0 0.1 0.00036 20.3 0.1 3.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3308 PF11751.3 EMD62548.1 - 0.038 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3308) HSA PF07529.8 EMD62548.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 HSA Ser_hydrolase PF06821.8 EMD62548.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Atg14 PF10186.4 EMD62549.1 - 0.003 16.5 4.5 0.0045 15.9 2.6 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EMD62549.1 - 0.0081 16.2 2.0 0.0081 16.2 1.4 2.8 2 2 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rop-like PF05082.8 EMD62549.1 - 0.052 13.0 1.0 0.27 10.7 0.2 2.3 1 1 1 2 2 2 0 Rop-like DUF1664 PF07889.7 EMD62549.1 - 0.066 13.0 7.9 0.77 9.5 2.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EMD62549.1 - 0.072 12.9 4.1 0.51 10.1 1.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EMD62549.1 - 0.073 12.8 3.8 0.22 11.2 0.4 2.6 1 1 0 2 2 2 0 Prefoldin subunit Iron_permease PF04120.7 EMD62549.1 - 0.079 12.5 2.5 3.5 7.2 0.5 2.6 1 1 1 2 2 2 0 Low affinity iron permease Reo_sigmaC PF04582.7 EMD62549.1 - 0.084 12.0 9.4 0.36 9.9 4.0 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EMD62549.1 - 0.14 11.7 5.3 0.13 11.7 2.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EMD62549.1 - 0.2 11.9 11.3 0.74 10.1 1.8 3.5 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMD62549.1 - 0.21 11.1 14.1 0.018 14.6 4.4 2.6 1 1 1 2 2 2 0 IncA protein DUF2408 PF10303.4 EMD62549.1 - 0.22 11.6 7.0 0.88 9.6 4.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 EMD62549.1 - 0.22 11.8 3.9 0.35 11.1 0.7 2.5 1 1 1 2 2 2 0 Spectrin repeat Syntaxin-6_N PF09177.6 EMD62549.1 - 0.23 11.8 7.2 5.1 7.5 0.3 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal GAS PF13851.1 EMD62549.1 - 0.24 10.5 6.4 0.4 9.8 2.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EMD62549.1 - 0.3 10.9 9.2 0.4 10.5 1.5 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EMD62549.1 - 0.45 10.3 3.6 1.1 9.1 0.3 2.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding PspB PF06667.7 EMD62549.1 - 0.63 10.0 5.0 2.6 8.0 0.0 3.3 2 1 0 4 4 3 0 Phage shock protein B ATG16 PF08614.6 EMD62549.1 - 0.67 9.7 9.0 0.28 10.9 2.6 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 EMD62549.1 - 1.7 9.0 7.2 0.76 10.1 1.9 2.4 2 1 1 3 3 3 0 Snapin/Pallidin DUF948 PF06103.6 EMD62549.1 - 2.1 8.2 11.6 2.3 8.1 0.7 3.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) LPP PF04728.8 EMD62549.1 - 2.9 7.7 13.0 8.3 6.2 1.1 3.8 2 1 2 4 4 3 0 Lipoprotein leucine-zipper CorA PF01544.13 EMD62549.1 - 4.6 6.1 11.4 0.35 9.8 2.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein XhlA PF10779.4 EMD62549.1 - 5.2 7.0 6.4 1.7 8.6 0.2 3.0 3 1 1 4 4 4 0 Haemolysin XhlA APH PF01636.18 EMD62551.1 - 0.059 13.0 1.3 0.054 13.2 0.9 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 EMD62554.1 - 1e-13 51.6 0.3 1.6e-13 51.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD62554.1 - 1.7e-13 50.5 0.0 3e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD62554.1 - 6.4e-10 38.9 0.1 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMD62554.1 - 3.2e-05 23.6 0.1 4.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EMD62554.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EMD62554.1 - 0.024 14.4 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EMD62554.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Cutinase PF01083.17 EMD62554.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EMD62554.1 - 0.11 12.0 0.4 0.29 10.7 0.2 1.6 1 1 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 EMD62554.1 - 0.12 11.5 0.0 0.49 9.5 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Anemone_cytotox PF06369.7 EMD62555.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Abhydrolase_6 PF12697.2 EMD62556.1 - 4.7e-27 95.3 0.5 1.3e-26 93.8 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD62556.1 - 3.2e-15 56.3 0.1 5.8e-14 52.1 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD62556.1 - 5.2e-13 48.9 0.0 2.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMD62556.1 - 3.8e-05 24.0 0.0 0.022 14.9 0.0 2.4 2 0 0 2 2 2 2 Thioesterase domain DUF915 PF06028.6 EMD62556.1 - 5.4e-05 22.4 0.0 0.00021 20.4 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EMD62556.1 - 0.00019 20.9 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EMD62556.1 - 0.00074 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EMD62556.1 - 0.0032 17.2 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EMD62556.1 - 0.006 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.8 EMD62556.1 - 0.018 14.6 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EMD62556.1 - 0.05 13.1 0.0 0.2 11.2 0.0 2.0 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.20 EMD62556.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMD62556.1 - 0.15 11.5 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Spo7 PF03907.8 EMD62557.1 - 4.3e-76 255.1 0.0 5.5e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein HTH_38 PF13936.1 EMD62558.1 - 3.4e-05 23.3 0.0 6.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sec7 PF01369.15 EMD62560.1 - 6e-62 208.6 3.0 1.3e-61 207.6 0.1 2.9 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EMD62560.1 - 2e-51 173.7 1.1 2e-51 173.7 0.8 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMD62560.1 - 6.1e-32 109.0 11.7 4.9e-31 106.1 0.1 5.5 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) Nop14 PF04147.7 EMD62560.1 - 0.65 7.8 28.0 1.8 6.3 19.4 1.6 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EMD62560.1 - 4 5.7 23.2 8 4.7 15.7 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EMD62560.1 - 4.6 5.1 14.7 11 3.9 10.2 1.5 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EMD62560.1 - 10 5.3 23.4 22 4.1 16.3 1.5 1 0 0 1 1 1 0 SDA1 2-oxoacid_dh PF00198.18 EMD62561.1 - 1.1e-71 240.7 0.1 1.4e-71 240.4 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMD62561.1 - 2.8e-19 68.5 0.8 8.2e-19 67.0 0.3 2.0 1 1 1 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EMD62561.1 - 1e-13 50.6 0.7 2.2e-13 49.5 0.5 1.6 1 0 0 1 1 1 1 e3 binding domain Fungal_trans_2 PF11951.3 EMD62562.1 - 5.8e-09 35.0 3.9 1.3e-08 33.8 2.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62562.1 - 1.3e-06 28.2 8.2 2.7e-06 27.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.15 EMD62563.1 - 1.6e-160 534.9 0.3 1.6e-160 534.9 0.2 2.3 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EMD62563.1 - 2.6e-13 49.3 0.0 1.3e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Ketoacyl-synt_C PF02801.17 EMD62563.1 - 0.084 12.7 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain CENP-L PF13092.1 EMD62564.1 - 1.5e-43 148.3 0.9 2.1e-43 147.9 0.6 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 PLDc_2 PF13091.1 EMD62565.1 - 2.4e-13 49.9 0.5 1.1e-06 28.4 0.0 4.0 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.17 EMD62565.1 - 3.8e-12 45.5 3.5 3.5e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_43 PF04616.9 EMD62566.1 - 5.4e-31 107.7 0.7 1.6e-30 106.1 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.20 EMD62567.1 - 2.2e-25 89.4 0.0 2.9e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62567.1 - 1.9e-16 60.5 0.0 2.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62567.1 - 9.2e-07 28.6 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62567.1 - 5.3e-05 22.7 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD62567.1 - 0.00028 20.9 0.0 0.0005 20.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD62567.1 - 0.0016 17.7 0.1 0.0038 16.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EMD62567.1 - 0.0034 16.3 0.0 0.0068 15.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 EMD62567.1 - 0.056 12.5 0.0 0.1 11.7 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) L31 PF09784.4 EMD62567.1 - 0.06 13.4 0.3 0.19 11.8 0.0 1.9 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Eno-Rase_NADH_b PF12242.3 EMD62567.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MCM PF00493.18 EMD62568.1 - 4.8e-127 423.3 0.1 6.9e-127 422.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMD62568.1 - 6.8e-17 62.0 0.0 1.7e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMD62568.1 - 1.1e-07 31.2 0.0 1.5e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMD62568.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMD62568.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain TAF4 PF05236.9 EMD62568.1 - 0.51 9.5 5.0 0.91 8.7 3.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rep_fac-A_3 PF08661.6 EMD62569.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 Plasmodium_Vir PF05795.6 EMD62570.1 - 0.031 13.4 0.2 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Yip1 PF04893.12 EMD62570.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Na_H_Exchanger PF00999.16 EMD62571.1 - 2.8e-35 121.5 21.7 3.8e-35 121.1 15.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Arif-1 PF06770.6 EMD62571.1 - 0.005 16.2 6.3 0.73 9.1 0.1 2.9 2 1 1 3 3 3 2 Actin-rearrangement-inducing factor (Arif-1) HupE_UreJ PF04955.7 EMD62571.1 - 0.042 13.1 0.1 0.042 13.1 0.0 3.6 4 1 0 4 4 4 0 HupE / UreJ protein YrhC PF14143.1 EMD62571.1 - 0.054 13.4 0.3 0.054 13.4 0.2 3.2 4 1 0 4 4 4 0 YrhC-like protein DUF1049 PF06305.6 EMD62571.1 - 4 6.9 8.5 0.39 10.2 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DJ-1_PfpI PF01965.19 EMD62573.1 - 3.2e-25 88.2 0.3 6.8e-25 87.2 0.2 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMD62573.1 - 8.4e-19 66.8 0.0 1.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EMD62573.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase Cutinase PF01083.17 EMD62574.1 - 2.6e-25 89.2 0.5 3.8e-25 88.6 0.3 1.3 1 0 0 1 1 1 1 Cutinase PLRV_ORF5 PF01690.12 EMD62574.1 - 1.3 8.1 16.0 1.8 7.6 11.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein EF-hand_1 PF00036.27 EMD62575.1 - 0.034 13.4 0.0 0.09 12.1 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EMD62575.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair NUMOD1 PF07453.8 EMD62576.1 - 0.071 12.9 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain Peptidase_C14 PF00656.17 EMD62577.1 - 0.0069 16.0 0.4 0.06 13.0 0.0 2.0 1 1 1 2 2 2 1 Caspase domain Ammonium_transp PF00909.16 EMD62578.1 - 1.4e-99 333.2 18.7 1.6e-99 333.0 12.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 EMD62578.1 - 0.062 13.0 5.3 9.2 6.1 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) NUDIX_4 PF14815.1 EMD62579.1 - 9.2e-19 66.9 0.0 2.7e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 EMD62579.1 - 6.5e-17 61.7 0.0 2.1e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMD62579.1 - 0.00012 21.5 0.4 0.00047 19.7 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EMD62579.1 - 0.013 15.6 0.0 0.2 11.8 0.0 2.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 EMD62579.1 - 0.91 9.8 7.9 2.9 8.2 5.5 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Glyco_transf_41 PF13844.1 EMD62580.1 - 4.7e-103 344.6 0.1 9.8e-55 185.3 0.0 2.8 1 1 2 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EMD62580.1 - 2.5e-22 78.2 15.8 7.5e-09 35.1 0.3 4.5 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EMD62580.1 - 1.7e-15 55.5 15.1 0.014 15.2 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMD62580.1 - 9.1e-15 53.5 14.1 0.0018 17.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMD62580.1 - 1.2e-13 49.8 6.9 0.0047 16.6 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMD62580.1 - 1.7e-13 50.2 12.6 1.8e-05 24.6 0.5 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD62580.1 - 3.2e-11 42.8 6.4 0.033 14.8 0.0 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMD62580.1 - 5.3e-10 39.6 10.1 0.00019 21.9 0.4 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD62580.1 - 2e-08 33.7 14.7 0.091 12.9 0.1 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMD62580.1 - 2.7e-06 27.5 13.6 0.00025 21.3 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD62580.1 - 0.00026 20.8 12.1 7.6 6.6 0.0 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD62580.1 - 0.00027 20.4 6.5 5.2 7.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD62580.1 - 0.0018 18.3 3.6 0.16 12.1 0.2 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EMD62580.1 - 0.0018 18.5 1.7 1.8 8.8 1.2 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain YkyA PF10368.4 EMD62580.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TPR_6 PF13174.1 EMD62580.1 - 0.52 10.8 9.4 1.3e+02 3.4 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMD62580.1 - 2.4 8.8 6.6 68 4.3 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu2_monoox_C PF03712.10 EMD62581.1 - 0.31 10.3 3.1 3.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Sec62 PF03839.11 EMD62582.1 - 1.5e-57 194.6 0.8 1.5e-57 194.6 0.5 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DASH_Spc34 PF08657.5 EMD62583.1 - 0.00034 20.3 4.8 0.21 11.2 0.4 2.2 2 0 0 2 2 2 2 DASH complex subunit Spc34 DUF2046 PF09755.4 EMD62583.1 - 0.0051 15.7 2.6 0.021 13.7 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.6 EMD62583.1 - 0.017 14.9 5.3 1.6 8.5 0.6 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IFP_35_N PF07334.8 EMD62583.1 - 0.031 14.2 0.5 0.09 12.7 0.3 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc24 PF08286.6 EMD62583.1 - 0.037 13.7 3.2 0.42 10.3 0.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Striatin PF08232.7 EMD62583.1 - 0.05 13.9 2.9 0.88 9.8 0.5 2.4 2 0 0 2 2 2 0 Striatin family BBP1_C PF15272.1 EMD62583.1 - 0.084 12.4 2.7 0.077 12.5 0.5 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal PspB PF06667.7 EMD62583.1 - 2.4 8.1 5.2 0.43 10.5 0.3 1.9 2 0 0 2 2 2 0 Phage shock protein B Fib_alpha PF08702.5 EMD62583.1 - 3.4 7.7 5.4 9.6 6.3 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EMD62583.1 - 3.4 7.2 8.4 0.96 8.9 0.9 2.3 2 0 0 2 2 2 0 Septum formation initiator Zn_clus PF00172.13 EMD62587.1 - 2.2e-07 30.6 11.6 4e-07 29.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ResIII PF04851.10 EMD62588.1 - 1.2e-21 77.3 0.2 2.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMD62588.1 - 3.7e-13 49.1 0.0 8.2e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD62588.1 - 4.2e-13 49.1 0.0 8.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EMD62588.1 - 0.0012 17.8 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMD62588.1 - 0.012 15.6 0.1 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain LcrG PF07216.7 EMD62588.1 - 0.025 14.6 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 LcrG protein AAA_24 PF13479.1 EMD62588.1 - 0.071 12.6 0.1 0.43 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain SNF2_N PF00176.18 EMD62588.1 - 0.072 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Mo-co_dimer PF03404.11 EMD62589.1 - 1.9e-53 179.6 0.3 4.1e-53 178.4 0.1 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EMD62589.1 - 2e-48 163.9 0.0 3.9e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EMD62589.1 - 1.4e-31 108.5 0.0 2.6e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD62589.1 - 1e-26 93.6 0.2 3e-26 92.1 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EMD62589.1 - 5.4e-24 83.7 0.1 1.3e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EMD62589.1 - 0.00041 20.3 0.2 0.011 15.6 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EMD62590.1 - 3e-31 107.9 0.0 6.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EMD62590.1 - 5.9e-28 98.1 0.1 1.1e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EMD62590.1 - 5.7e-15 54.9 0.0 1.6e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EMD62590.1 - 1.4e-14 53.4 0.2 3.6e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EMD62590.1 - 1.7e-14 53.9 6.4 1.2e-13 51.2 0.6 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EMD62590.1 - 3.6e-13 49.3 3.0 1.3e-11 44.3 2.1 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 EMD62590.1 - 1.1e-08 34.5 0.0 2.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EMD62590.1 - 6.5e-08 32.8 0.0 4.6e-05 23.5 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD62590.1 - 1.4e-06 27.4 0.6 0.2 10.5 0.0 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD62590.1 - 0.00096 18.9 0.1 1.8 8.3 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD62590.1 - 0.014 14.3 0.0 0.089 11.6 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EMD62590.1 - 0.02 13.7 0.8 0.67 8.7 0.4 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMD62590.1 - 0.038 14.0 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EMD62590.1 - 0.27 11.2 0.7 4.9 7.1 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.17 EMD62591.1 - 7.1e-18 64.3 0.0 7.9e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMD62592.1 - 5.9e-42 143.6 45.4 5.9e-42 143.6 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62592.1 - 1.3e-05 23.9 34.9 0.00019 20.1 24.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MbeB_N PF04837.7 EMD62593.1 - 0.079 13.0 0.7 0.15 12.2 0.5 1.5 1 0 0 1 1 1 0 MbeB-like, N-term conserved region V-SNARE_C PF12352.3 EMD62594.1 - 7.5e-15 54.7 0.6 4.9e-14 52.1 0.2 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMD62594.1 - 0.0006 19.4 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 1 Sec20 KxDL PF10241.4 EMD62594.1 - 0.025 14.4 3.2 0.41 10.5 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Cortex-I_coil PF09304.5 EMD62594.1 - 0.03 14.3 1.2 0.13 12.2 0.3 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Cast PF10174.4 EMD62594.1 - 0.065 11.2 1.8 3.5 5.5 0.0 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone PilJ PF13675.1 EMD62594.1 - 0.099 12.9 5.4 0.068 13.4 2.2 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vps5 PF09325.5 EMD62594.1 - 0.93 8.7 4.7 7.9 5.6 1.4 2.5 2 1 0 2 2 2 0 Vps5 C terminal like T2SM PF04612.7 EMD62594.1 - 2.9 7.6 5.8 4.9 6.9 1.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Peptidase_M28 PF04389.12 EMD62595.1 - 9e-24 84.1 0.3 2.6e-23 82.6 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD62595.1 - 0.00032 20.2 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF946 PF06101.6 EMD62596.1 - 6.4e-06 24.4 0.0 9.5e-06 23.8 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF3138 PF11336.3 EMD62596.1 - 0.076 11.1 0.4 0.14 10.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Med7 PF05983.6 EMD62597.1 - 1.3 8.8 4.4 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 MED7 protein Cu-oxidase_3 PF07732.10 EMD62599.1 - 2.7e-40 136.7 6.4 4.6e-40 136.0 1.6 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD62599.1 - 5.8e-40 135.9 7.1 1e-38 131.9 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMD62599.1 - 4.5e-35 120.8 0.4 2.7e-34 118.3 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase p450 PF00067.17 EMD62600.1 - 4.1e-41 140.9 0.0 5.5e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORF6C PF10552.4 EMD62600.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 ORF6C domain FAD_binding_4 PF01565.18 EMD62601.1 - 7.2e-26 90.3 3.5 1.9e-25 88.9 2.4 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD62601.1 - 5.8e-06 26.1 0.2 1.2e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like polyprenyl_synt PF00348.12 EMD62602.1 - 5.1e-42 143.5 0.0 9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EMD62602.1 - 1.7e-06 27.4 0.2 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain p450 PF00067.17 EMD62603.1 - 5.4e-63 213.1 0.0 6.6e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.1 EMD62604.1 - 1.5e-30 106.6 0.0 2e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD62604.1 - 1.8e-25 89.5 0.0 3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EMD62604.1 - 6.9e-11 42.2 0.1 6.9e-11 42.2 0.1 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EMD62604.1 - 3.7e-08 32.2 0.0 1.2e-05 23.9 0.0 3.2 1 1 2 3 3 3 2 Chitin synthase Glyco_transf_21 PF13506.1 EMD62604.1 - 7e-07 28.6 0.0 3.7e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EMD62604.1 - 6.7e-06 25.3 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EMD62604.1 - 0.004 17.4 0.0 0.02 15.1 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 LysM PF01476.15 EMD62605.1 - 6.5e-15 54.7 0.2 2.5e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 LysM domain Dioxygenase_C PF00775.16 EMD62606.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dioxygenase FbpA PF05833.6 EMD62606.1 - 0.095 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) p450 PF00067.17 EMD62607.1 - 1.3e-61 208.5 0.0 1.6e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.16 EMD62608.1 - 7.9e-40 136.7 23.1 1.6e-24 86.4 4.9 2.9 2 2 1 3 3 3 2 POT family Fungal_trans PF04082.13 EMD62609.1 - 4.5e-18 65.0 1.0 7.8e-18 64.2 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD62610.1 - 3.3e-30 105.0 18.4 3.3e-30 105.0 12.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 EMD62610.1 - 0.43 10.2 4.3 13 5.4 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EMD62610.1 - 0.74 9.5 10.0 2 8.1 1.7 2.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain 2TM PF13239.1 EMD62610.1 - 1.9 8.6 6.6 0.94 9.5 0.1 3.2 3 0 0 3 3 3 0 2TM domain DUF515 PF04415.7 EMD62611.1 - 0.19 9.9 0.3 0.27 9.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AA_permease_2 PF13520.1 EMD62612.1 - 3.7e-47 160.8 46.6 5.2e-47 160.3 32.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD62612.1 - 3.6e-18 65.1 35.2 5e-18 64.6 24.4 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.14 EMD62613.1 - 2.8e-48 164.6 0.0 3.7e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD62613.1 - 8.5e-32 110.4 0.1 1.4e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD62613.1 - 1.7e-06 27.2 6.0 4.4e-05 22.5 1.8 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMD62613.1 - 2.7e-05 23.3 1.0 0.003 16.6 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EMD62613.1 - 0.00011 21.1 2.1 0.00081 18.3 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMD62613.1 - 0.00051 20.0 2.2 0.0016 18.3 1.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD62613.1 - 0.0041 17.0 2.2 0.013 15.4 0.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62613.1 - 0.018 13.9 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD62613.1 - 0.21 11.6 1.6 6.1 6.8 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD62613.1 - 0.32 10.0 2.4 1.3 7.9 1.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EMD62613.1 - 0.32 10.6 2.5 0.75 9.4 1.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMD62613.1 - 0.43 9.3 1.4 0.68 8.7 1.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADC PF06314.6 EMD62614.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) FMN_dh PF01070.13 EMD62615.1 - 1.1e-109 366.5 0.1 1.4e-109 366.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMD62615.1 - 2.4e-20 72.0 0.0 6.7e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMD62615.1 - 7.1e-05 21.8 0.0 0.00066 18.6 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 EMD62615.1 - 0.0029 16.7 1.6 0.3 10.1 0.1 2.3 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EMD62615.1 - 0.013 14.4 2.5 0.014 14.2 0.2 2.1 3 1 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain BNR_2 PF13088.1 EMD62616.1 - 4.7e-59 199.9 2.2 6.3e-59 199.5 1.6 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EMD62616.1 - 4.1e-08 31.8 10.3 0.04 13.7 0.2 4.1 3 0 0 3 3 3 3 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EMD62616.1 - 6e-07 29.1 0.8 0.51 9.9 0.0 3.3 3 0 0 3 3 3 3 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 EMD62616.1 - 0.00028 19.9 1.3 0.26 10.2 0.1 3.1 3 0 0 3 3 3 3 Photosynthesis system II assembly factor YCF48 Sugar_tr PF00083.19 EMD62617.1 - 9.8e-88 294.6 20.7 1.1e-87 294.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62617.1 - 6.4e-14 51.4 29.4 6.4e-14 51.4 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EMD62617.1 - 6.5e-05 21.7 0.1 0.00013 20.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) UNC-93 PF05978.11 EMD62617.1 - 0.0025 17.3 1.2 0.0025 17.3 0.8 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Aldo_ket_red PF00248.16 EMD62618.1 - 3.6e-49 167.0 0.0 4.2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EMD62619.1 - 3.7e-07 29.2 0.1 7.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62619.1 - 7.5e-07 28.9 8.5 1.4e-06 28.1 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EMD62620.1 - 5.8e-11 42.2 0.0 2.4e-10 40.2 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD62620.1 - 0.02 13.7 0.0 0.041 12.7 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMD62620.1 - 0.081 11.8 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein ORC6 PF05460.8 EMD62621.1 - 0.28 10.2 6.4 0.35 9.9 4.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4106 PF13388.1 EMD62621.1 - 0.39 9.6 5.2 0.45 9.4 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Aa_trans PF01490.13 EMD62622.1 - 3.4e-77 259.6 26.1 4.7e-77 259.1 18.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4161 PF13722.1 EMD62622.1 - 3.3 8.0 8.9 0.29 11.4 1.6 2.6 2 1 1 3 3 3 0 C-terminal domain on CstA (DUF4161) Endonuc_Holl PF10107.4 EMD62623.1 - 0.073 12.7 3.1 0.099 12.3 2.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DDHD PF02862.12 EMD62623.1 - 0.16 11.7 2.7 0.18 11.5 1.8 1.1 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.4 EMD62623.1 - 0.67 8.1 5.7 0.76 7.9 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein ATP-synt_B PF00430.13 EMD62623.1 - 1.9 8.3 8.2 2.7 7.7 5.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF605 PF04652.11 EMD62624.1 - 0.022 14.2 19.3 0.031 13.7 13.4 1.2 1 0 0 1 1 1 0 Vta1 like HET PF06985.6 EMD62625.1 - 7.9e-23 81.1 0.0 1.9e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EMD62627.1 - 9.9e-72 241.1 0.0 1.8e-71 240.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62627.1 - 2.3e-51 174.3 0.0 4.1e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RecO_C PF02565.10 EMD62627.1 - 0.0029 17.4 0.0 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 Recombination protein O C terminal Kinase-like PF14531.1 EMD62627.1 - 0.0029 16.6 0.0 0.01 14.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Arm PF00514.18 EMD62627.1 - 0.0042 16.8 0.0 3.9 7.4 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EMD62627.1 - 0.0053 15.9 0.5 1.3 8.0 0.2 3.0 2 1 0 2 2 2 1 V-ATPase subunit H adh_short PF00106.20 EMD62628.1 - 2.6e-20 73.0 0.5 2e-19 70.1 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62628.1 - 1e-15 58.2 0.4 3e-15 56.6 0.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62628.1 - 1.1e-11 44.7 1.1 2.9e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EMD62628.1 - 0.0055 16.1 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EMD62628.1 - 0.0075 15.8 0.6 0.017 14.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EMD62628.1 - 0.0082 16.5 0.3 0.024 15.0 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMD62628.1 - 0.034 13.8 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EMD62628.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMD62628.1 - 0.058 13.4 2.2 0.22 11.5 0.3 2.2 1 1 1 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 EMD62628.1 - 0.064 13.5 0.2 1.5 9.0 0.1 2.4 2 2 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 EMD62628.1 - 0.068 12.6 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EMD62628.1 - 0.075 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain AA_kinase PF00696.23 EMD62628.1 - 0.078 12.4 0.2 0.19 11.2 0.1 1.9 1 1 0 1 1 1 0 Amino acid kinase family 3HCDH_N PF02737.13 EMD62628.1 - 0.11 12.1 0.1 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.24 EMD62629.1 - 2e-16 60.3 0.0 9.1e-07 29.1 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EMD62629.1 - 2.1e-13 50.3 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 EMD62629.1 - 3.2e-05 24.7 0.0 8.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD62629.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD62629.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EMD62629.1 - 0.0021 18.2 0.0 0.064 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EMD62629.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD62629.1 - 0.013 15.1 0.0 0.065 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD62629.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD62629.1 - 0.056 13.2 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain But2 PF09792.4 EMD62630.1 - 5.5e-47 159.1 1.3 9.4e-47 158.3 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain NmrA PF05368.8 EMD62631.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD62631.1 - 1.2e-09 38.4 0.0 1.7e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD62631.1 - 0.018 14.0 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EMD62631.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD62631.1 - 0.065 11.9 0.0 0.15 10.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMD62631.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EMD62631.1 - 0.14 11.7 0.0 0.51 9.9 0.0 1.9 1 1 0 1 1 1 0 KR domain COX14 PF14880.1 EMD62632.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Cellulase PF00150.13 EMD62633.1 - 1.6e-49 168.6 5.9 2.1e-49 168.2 4.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2057 PF09829.4 EMD62633.1 - 3 7.4 5.8 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-RING_5 PF14634.1 EMD62634.1 - 0.00089 18.9 3.9 0.0018 17.9 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain IncA PF04156.9 EMD62634.1 - 1.2 8.6 5.0 2.4 7.7 3.4 1.4 1 0 0 1 1 1 0 IncA protein p450 PF00067.17 EMD62636.1 - 2.9e-62 210.6 0.0 4.1e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KGK PF08872.5 EMD62636.1 - 0.028 14.5 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 KGK domain RRM_1 PF00076.17 EMD62638.1 - 3.1e-11 42.7 0.4 4e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD62638.1 - 5.3e-11 42.3 0.3 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD62638.1 - 3.7e-07 29.8 0.1 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C48 PF02902.14 EMD62638.1 - 0.1 12.2 0.4 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain 4HBT PF03061.17 EMD62640.1 - 0.0019 18.2 0.2 2.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MHYT PF03707.11 EMD62642.1 - 7.6e-07 29.1 19.4 0.00057 19.9 0.1 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat WD40 PF00400.27 EMD62643.1 - 8.8e-52 171.2 16.9 4.9e-13 48.4 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMD62643.1 - 1.5e-06 27.6 0.0 0.2 11.1 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EMD62643.1 - 0.0055 14.6 0.9 0.098 10.4 0.1 2.4 3 0 0 3 3 3 1 IKI3 family Coatomer_WDAD PF04053.9 EMD62643.1 - 0.082 11.6 2.5 0.75 8.5 0.1 2.2 2 0 0 2 2 2 0 Coatomer WD associated region MmlI PF09448.5 EMD62643.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase CTP_transf_2 PF01467.21 EMD62644.1 - 5e-18 65.6 0.0 9.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase Tcp11 PF05794.8 EMD62645.1 - 8.4e-79 265.3 0.0 4.3e-78 263.0 0.0 2.0 2 1 0 2 2 2 1 T-complex protein 11 BCS1_N PF08740.6 EMD62646.1 - 4.2e-30 104.7 0.0 9.7e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMD62646.1 - 2e-16 60.4 0.0 5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD62646.1 - 0.013 16.2 0.0 0.046 14.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EMD62646.1 - 0.056 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD62646.1 - 0.098 12.8 0.4 3.5 7.7 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 EMD62646.1 - 0.63 9.9 2.7 3.5 7.4 1.9 2.3 1 1 0 1 1 1 0 AAA domain ALAD PF00490.16 EMD62647.1 - 1.3e-116 389.0 0.0 1.4e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF2231 PF09990.4 EMD62648.1 - 0.77 10.1 6.5 0.6 10.4 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Pectinesterase PF01095.14 EMD62650.1 - 4.4e-46 156.7 1.9 6.2e-46 156.3 1.3 1.1 1 0 0 1 1 1 1 Pectinesterase DUF1996 PF09362.5 EMD62653.1 - 9.2e-53 179.3 0.3 1.1e-52 179.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DLH PF01738.13 EMD62654.1 - 9.2e-25 87.2 0.0 1.1e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMD62654.1 - 7.4e-08 32.2 0.0 9.9e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD62654.1 - 0.00011 22.1 0.0 0.23 11.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family AMP-binding PF00501.23 EMD62655.1 - 1.9e-54 184.6 0.2 3.3e-53 180.5 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD62655.1 - 9.7e-12 45.6 0.1 3.6e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EMD62656.1 - 4.9e-19 68.0 0.0 1.5e-13 50.0 0.0 2.5 2 1 0 2 2 2 2 Transferase family ACOX PF01756.14 EMD62657.1 - 6.1e-36 123.5 0.2 1.2e-35 122.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMD62657.1 - 4.7e-26 91.5 0.1 1.2e-25 90.2 0.1 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMD62657.1 - 3.2e-07 29.7 0.1 9.6e-07 28.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMD62657.1 - 0.00033 20.7 0.6 0.0053 16.8 0.4 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD62657.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Zn_clus PF00172.13 EMD62658.1 - 1.4e-08 34.5 14.1 2.5e-08 33.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 EMD62659.1 - 7.6e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMD62659.1 - 1.2e-08 34.5 0.1 2.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMD62659.1 - 1.5e-05 25.1 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD62659.1 - 0.0022 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD62659.1 - 0.0035 17.1 0.2 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF377 PF04041.8 EMD62659.1 - 0.034 12.8 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF377) CTP_transf_2 PF01467.21 EMD62661.1 - 7e-16 58.6 0.0 4.8e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase p450 PF00067.17 EMD62662.1 - 4.3e-63 213.4 0.0 5.2e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MIP PF00230.15 EMD62663.1 - 1.2e-39 136.1 13.3 1.5e-39 135.8 9.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF165 PF02592.10 EMD62663.1 - 0.064 13.4 5.9 0.15 12.2 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF3493 PF11998.3 EMD62663.1 - 7.5 6.5 12.1 0.83 9.5 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3493) HAD_2 PF13419.1 EMD62665.1 - 8.6e-14 52.1 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD62665.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMD62665.1 - 2.1e-07 31.5 0.0 6.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD62665.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WSC PF01822.14 EMD62666.1 - 1.8e-51 171.9 44.1 8.6e-18 64.0 8.3 3.5 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EMD62666.1 - 9.7e-27 93.5 0.0 3.7e-25 88.4 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EMD62666.1 - 2.1e-19 69.4 0.0 4.5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Methyltransf_23 PF13489.1 EMD62667.1 - 1e-20 74.0 0.1 3.2e-20 72.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62667.1 - 2e-11 44.4 0.1 3.4e-10 40.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62667.1 - 2.4e-11 43.4 0.0 1.3e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62667.1 - 5.5e-10 39.6 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD62667.1 - 3.8e-09 36.9 0.0 2.1e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD62667.1 - 3.4e-06 27.3 0.0 9.5e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EMD62667.1 - 3e-05 23.4 0.0 0.00024 20.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EMD62667.1 - 3.3e-05 23.1 0.0 7.6e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EMD62667.1 - 0.00065 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMD62667.1 - 0.00066 19.6 0.0 0.0066 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMD62667.1 - 0.00085 18.5 0.0 0.049 12.8 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase FtsJ PF01728.14 EMD62667.1 - 0.0039 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EMD62667.1 - 0.005 15.9 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EMD62667.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 EMD62667.1 - 0.039 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EMD62667.1 - 0.054 12.6 0.0 0.093 11.8 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF605 PF04652.11 EMD62668.1 - 0.0061 16.0 22.4 0.0073 15.7 15.6 1.1 1 0 0 1 1 1 1 Vta1 like DUF1675 PF07897.6 EMD62668.1 - 0.051 13.4 12.9 0.072 12.9 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SOG2 PF10428.4 EMD62668.1 - 0.43 9.1 16.3 0.53 8.8 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pneumo_att_G PF05539.6 EMD62668.1 - 2.3 7.4 13.7 2.9 7.1 9.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MIP-T3 PF10243.4 EMD62668.1 - 3 6.2 24.0 3.9 5.8 16.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 EMD62668.1 - 9.5 3.7 7.8 12 3.4 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CTP_transf_2 PF01467.21 EMD62670.1 - 0.021 14.8 0.0 1.1 9.2 0.0 2.5 1 1 0 1 1 1 0 Cytidylyltransferase Kelch_4 PF13418.1 EMD62671.1 - 5.6e-05 22.8 4.1 0.32 10.8 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EMD62671.1 - 0.00038 20.5 15.9 0.071 13.3 0.7 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD62671.1 - 0.00069 19.5 0.5 0.076 12.9 0.0 3.4 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.5 EMD62671.1 - 0.05 12.9 0.6 0.12 11.7 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EMD62671.1 - 0.25 10.9 2.6 0.45 10.1 1.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.1 EMD62671.1 - 1 9.4 0.0 1 9.4 0.0 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Meth_synt_2 PF01717.13 EMD62672.1 - 5.7e-143 475.7 0.0 3e-137 456.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMD62672.1 - 5.4e-126 420.0 0.2 5.7e-114 380.5 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EMD62672.1 - 6e-05 22.1 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) adh_short PF00106.20 EMD62673.1 - 4.5e-30 104.7 0.1 6.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62673.1 - 1.2e-21 77.6 0.1 1.2e-20 74.2 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62673.1 - 4.9e-15 55.6 0.0 6.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62673.1 - 0.0006 19.3 0.3 0.0035 16.8 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD62673.1 - 0.0039 16.3 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EMD62673.1 - 0.043 12.7 0.1 0.063 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RDD PF06271.7 EMD62674.1 - 5 7.0 19.0 5.2 6.9 6.0 2.4 1 1 1 2 2 2 0 RDD family FAD_binding_4 PF01565.18 EMD62675.1 - 8.7e-27 93.2 0.4 1.4e-26 92.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD62675.1 - 0.0085 15.9 0.3 0.026 14.4 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like HSP20 PF00011.16 EMD62676.1 - 6.2e-14 51.6 0.2 2.6e-09 36.8 0.0 2.7 2 1 1 3 3 3 2 Hsp20/alpha crystallin family Herpes_UL32 PF06070.6 EMD62676.1 - 2 6.7 12.5 2.3 6.5 8.7 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Hid1 PF12722.2 EMD62676.1 - 5.6 4.5 7.1 7.5 4.0 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fungal_trans_2 PF11951.3 EMD62677.1 - 1.3e-09 37.2 0.2 2.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62677.1 - 9.8e-08 31.7 9.4 1.9e-07 30.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EMD62678.1 - 2.5e-55 187.4 9.4 2.5e-55 187.4 6.5 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4579 PF15158.1 EMD62678.1 - 0.074 12.5 0.4 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF3382 PF11862.3 EMD62678.1 - 1.2 9.0 6.5 2.1 8.3 3.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) Trypsin PF00089.21 EMD62679.1 - 2.8e-08 33.6 8.3 7.5e-08 32.2 5.8 1.7 1 1 0 1 1 1 1 Trypsin Pro_Al_protease PF02983.9 EMD62679.1 - 5.8e-05 22.9 11.4 0.00016 21.5 0.6 2.7 2 0 0 2 2 2 2 Alpha-lytic protease prodomain Secretin_N PF03958.12 EMD62679.1 - 0.12 12.5 0.8 3.3 7.9 0.5 2.7 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain TatD_DNase PF01026.16 EMD62681.1 - 1.7e-40 138.8 0.0 2e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Glyco_transf_36 PF06165.6 EMD62682.1 - 1.9e-21 75.9 0.0 5.1e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid PF05592.6 EMD62682.1 - 7.3e-05 21.1 0.1 0.00013 20.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EMD62682.1 - 0.00059 18.6 0.3 0.00088 18.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GT36_AF PF06205.6 EMD62682.1 - 0.0047 16.6 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family WD40 PF00400.27 EMD62683.1 - 2.3e-07 30.4 8.4 5.3e-06 26.1 0.2 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 EMD62683.1 - 0.044 11.9 0.5 0.096 10.8 0.0 1.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 BPL_LplA_LipB PF03099.14 EMD62684.1 - 2.1e-11 43.9 0.0 9.6e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FlaF PF07309.6 EMD62686.1 - 0.024 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF C1_4 PF07975.7 EMD62686.1 - 9.6 6.2 14.1 2.3 8.3 5.7 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain FAD_binding_3 PF01494.14 EMD62687.1 - 3.7e-29 101.8 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD62687.1 - 2.8e-09 36.3 0.0 0.00085 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD62687.1 - 0.00032 19.7 0.1 1.5 7.6 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 EMD62687.1 - 0.0079 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase SSP160 PF06933.6 EMD62687.1 - 4.1 5.2 5.4 5.3 4.9 3.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GRAB PF10375.4 EMD62688.1 - 1.5e-08 33.8 0.1 3.3e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Myosin_tail_1 PF01576.14 EMD62688.1 - 8.3e-05 20.5 47.9 0.00014 19.8 33.2 1.3 1 0 0 1 1 1 1 Myosin tail DUF904 PF06005.7 EMD62688.1 - 0.00057 20.1 5.8 0.00057 20.1 4.1 5.9 4 2 1 5 5 3 1 Protein of unknown function (DUF904) Rab5-bind PF09311.6 EMD62688.1 - 0.002 18.0 39.0 0.002 18.0 27.0 3.7 2 1 2 4 4 4 1 Rabaptin-like protein bZIP_1 PF00170.16 EMD62688.1 - 0.0023 17.8 4.3 0.0023 17.8 3.0 6.0 8 0 0 8 8 7 1 bZIP transcription factor DUF2353 PF09789.4 EMD62688.1 - 0.0036 16.6 24.6 0.0036 16.6 17.1 3.2 1 1 2 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) Filament PF00038.16 EMD62688.1 - 0.0048 16.4 44.2 0.64 9.4 30.6 2.9 1 1 0 1 1 1 1 Intermediate filament protein Baculo_PEP_C PF04513.7 EMD62688.1 - 0.032 14.0 16.4 0.48 10.2 0.1 3.7 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EMD62688.1 - 0.2 10.8 13.2 3.4 6.7 0.7 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMD62688.1 - 0.56 10.3 25.7 0.81 9.7 5.1 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.1 EMD62688.1 - 1 9.5 27.6 0.073 13.1 1.8 4.8 2 2 3 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 DUF3138 PF11336.3 EMD62688.1 - 3 5.9 12.5 2.6 6.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.7 EMD62688.1 - 5.8 7.2 16.9 12 6.2 1.5 4.6 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMD62688.1 - 5.8 6.4 61.0 0.36 10.3 3.0 4.6 2 1 2 4 4 4 0 IncA protein Ribosomal_L32p PF01783.18 EMD62689.1 - 2.8e-10 40.1 2.1 6.5e-10 39.0 1.4 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF4543 PF15076.1 EMD62689.1 - 3.2 7.8 7.3 1.2 9.1 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Septin PF00735.13 EMD62690.1 - 2.8e-112 374.3 0.5 3.4e-112 374.0 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMD62690.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMD62690.1 - 1.2e-05 24.5 0.0 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMD62690.1 - 1.6e-05 24.1 0.0 5.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EMD62690.1 - 3.8e-05 23.2 0.2 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMD62690.1 - 0.00057 19.7 0.2 0.79 9.5 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EMD62690.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EMD62690.1 - 0.01 15.2 0.2 0.021 14.2 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMD62690.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EMD62690.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMD62690.1 - 0.021 15.1 0.6 0.044 14.0 0.4 1.9 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 EMD62690.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EMD62690.1 - 0.032 13.6 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Ras family T2SE PF00437.15 EMD62690.1 - 0.072 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Yae1_N PF09811.4 EMD62691.1 - 6e-09 35.2 2.3 9.3e-09 34.6 1.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.6 EMD62692.1 - 5.5e-144 479.6 0.1 7.3e-144 479.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMD62692.1 - 2.6e-09 35.6 0.2 1.5e-06 26.5 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMD62692.1 - 0.0046 16.7 0.1 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMD62692.1 - 0.017 14.2 0.1 0.066 12.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UPF0547 PF10571.4 EMD62692.1 - 0.89 9.3 2.8 2.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 MFS_1 PF07690.11 EMD62693.1 - 1.5e-16 60.0 43.6 1.8e-14 53.2 30.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Mpp10 PF04006.7 EMD62695.1 - 6.4e-93 312.1 69.5 2.3e-92 310.3 48.2 1.7 1 1 0 1 1 1 1 Mpp10 protein Mito_carr PF00153.22 EMD62696.1 - 3.1e-70 231.9 0.1 7.3e-25 86.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 EMD62697.1 - 1.2e-48 163.2 0.2 1.4e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribosomal_S21 PF01165.15 EMD62697.1 - 0.028 13.8 0.1 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 DUF4003 PF13170.1 EMD62697.1 - 0.049 12.8 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Beta-lactamase PF00144.19 EMD62698.1 - 1.4e-38 132.8 0.0 2.1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase PIG-X PF08320.7 EMD62698.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 Peptidase_S11 PF00768.15 EMD62698.1 - 0.093 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase He_PIG PF05345.7 EMD62698.1 - 0.095 12.7 0.3 0.28 11.2 0.2 1.8 1 0 0 1 1 1 0 Putative Ig domain HOK_GEF PF01848.11 EMD62699.1 - 0.081 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Hok/gef family DUF1049 PF06305.6 EMD62699.1 - 0.1 12.0 1.3 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HhH-GPD PF00730.20 EMD62700.1 - 1.3e-11 44.7 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.3 EMD62703.1 - 4.1e-11 42.5 6.2 1.3e-10 40.9 4.3 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EMD62703.1 - 1.9e-08 34.2 1.6 0.011 15.7 0.0 3.9 2 2 1 3 3 3 3 Receptor L domain LRR_9 PF14580.1 EMD62703.1 - 0.043 13.3 1.2 2.3 7.7 0.0 2.6 2 1 1 3 3 3 0 Leucine-rich repeat Anp1 PF03452.9 EMD62704.1 - 8.7e-107 356.2 0.0 1.1e-106 355.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 G-patch PF01585.18 EMD62705.1 - 9e-12 44.5 1.0 9e-12 44.5 0.7 1.8 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 EMD62705.1 - 2.3e-05 24.1 0.1 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EMD62705.1 - 0.00067 19.4 0.1 0.00067 19.4 0.1 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 EMD62705.1 - 0.0008 19.0 0.1 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dec-1 PF04624.9 EMD62705.1 - 0.18 11.4 3.2 0.67 9.6 2.2 2.0 1 0 0 1 1 1 0 Dec-1 repeat AMP-binding PF00501.23 EMD62706.1 - 5.5e-86 288.5 0.0 6.5e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD62706.1 - 1.3e-14 54.8 0.1 1.6e-13 51.3 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EMD62706.1 - 0.00064 18.3 0.0 0.0041 15.6 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter ANTAR PF03861.9 EMD62707.1 - 0.8 9.3 4.5 0.45 10.1 0.1 2.6 3 0 0 3 3 3 0 ANTAR domain Zn_clus PF00172.13 EMD62708.1 - 1.2e-08 34.7 9.0 1.2e-08 34.7 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD62708.1 - 2.5e-08 32.9 0.3 3.9e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABM PF03992.11 EMD62709.1 - 0.00029 20.7 0.0 0.37 10.8 0.1 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Glyco_hydro_92 PF07971.7 EMD62710.1 - 2.8e-152 507.8 0.0 5.9e-112 374.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 Y_phosphatase2 PF03162.8 EMD62711.1 - 1.1e-42 145.1 0.0 2.2e-42 144.2 0.0 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMD62711.1 - 7.1e-12 45.8 0.0 8.7e-11 42.3 0.0 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMD62711.1 - 0.00031 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD62711.1 - 0.001 18.4 0.1 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3984 PF13136.1 EMD62712.1 - 3.4e-67 226.9 26.1 4.1e-66 223.4 14.6 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3984) Glyco_transf_22 PF03901.12 EMD62713.1 - 3.2e-84 283.3 14.7 4e-84 283.0 10.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 EMD62714.1 - 2.3e-48 164.6 0.2 2.6e-33 115.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62714.1 - 3.1e-24 85.4 0.2 1.9e-23 82.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD62714.1 - 7.2e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like JmjC PF02373.17 EMD62716.1 - 8.1e-10 38.9 0.4 7.1e-09 35.9 0.3 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EMD62716.1 - 0.00034 20.6 5.5 0.00034 20.6 3.8 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EMD62716.1 - 0.0021 17.5 0.0 0.0064 15.9 0.0 1.8 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EMD62717.1 - 3.2e-32 111.7 19.9 4.5e-32 111.2 13.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Metallophos_2 PF12850.2 EMD62718.1 - 2.2e-14 53.5 0.0 3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Inositol_P PF00459.20 EMD62719.1 - 2.8e-41 141.6 1.7 1.5e-39 135.9 1.2 2.1 1 1 0 1 1 1 1 Inositol monophosphatase family DUF3987 PF13148.1 EMD62719.1 - 0.03 12.8 0.9 0.053 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ecl1 PF12855.2 EMD62721.1 - 9.4e-15 53.6 4.0 1.5e-14 52.9 2.7 1.4 1 0 0 1 1 1 1 Life-span regulatory factor PLATZ PF04640.9 EMD62721.1 - 0.045 13.9 3.7 0.08 13.1 2.6 1.4 1 0 0 1 1 1 0 PLATZ transcription factor SR-25 PF10500.4 EMD62721.1 - 7.9 5.8 20.9 2.5 7.5 2.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aminotran_5 PF00266.14 EMD62723.1 - 1.1e-29 103.3 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMD62723.1 - 0.00011 20.6 0.0 0.00015 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD62723.1 - 0.00017 20.6 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 EMD62723.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain TPR_11 PF13414.1 EMD62727.1 - 0.068 12.8 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 TPR repeat AhpC-TSA PF00578.16 EMD62728.1 - 7.2e-24 83.8 0.0 1.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMD62728.1 - 8.5e-15 54.5 0.1 2e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EMD62728.1 - 0.035 14.0 0.0 0.45 10.4 0.0 2.1 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme 5_nucleotid_C PF02872.13 EMD62728.1 - 0.093 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Aa_trans PF01490.13 EMD62729.1 - 2.4e-38 131.7 35.0 2.9e-38 131.4 24.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMD62729.1 - 0.00094 18.0 20.3 0.0017 17.2 14.1 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family zf-RING_2 PF13639.1 EMD62730.1 - 1.7e-10 40.5 4.8 1.7e-10 40.5 3.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EMD62730.1 - 2.6e-06 27.1 1.8 2.6e-06 27.1 1.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMD62730.1 - 2.9e-05 24.0 2.9 2.9e-05 24.0 2.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger Prok-RING_1 PF14446.1 EMD62730.1 - 9.7e-05 22.0 6.1 0.0005 19.7 2.0 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 EMD62730.1 - 0.00016 21.2 4.1 0.00016 21.2 2.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD62730.1 - 0.00017 21.5 6.6 0.00017 21.5 4.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD62730.1 - 0.0002 20.9 5.4 0.0002 20.9 3.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 EMD62730.1 - 0.00024 20.9 11.0 0.00064 19.6 5.7 2.7 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EMD62730.1 - 0.00074 19.0 8.3 0.00074 19.0 5.7 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EMD62730.1 - 0.0035 16.9 3.8 0.0035 16.9 2.6 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMD62730.1 - 0.0049 16.5 7.0 0.0092 15.6 4.8 1.5 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.12 EMD62730.1 - 0.0096 15.3 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING-like PF08746.6 EMD62730.1 - 0.011 15.7 4.3 0.011 15.7 3.0 2.3 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.2 EMD62730.1 - 0.012 15.6 5.8 0.012 15.6 4.0 1.8 2 0 0 2 2 1 0 RING-variant domain Baculo_IE-1 PF05290.6 EMD62730.1 - 0.19 11.4 3.9 0.33 10.6 2.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Baculo_RING PF05883.6 EMD62730.1 - 0.3 10.9 3.2 0.57 10.0 2.2 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain UPF0547 PF10571.4 EMD62730.1 - 0.46 10.2 4.2 5.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 EMD62730.1 - 0.71 9.6 5.1 14 5.5 3.6 2.4 1 1 0 1 1 1 0 zinc-ribbons zf-Di19 PF05605.7 EMD62730.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Gly_transf_sug PF04488.10 EMD62734.1 - 8e-08 32.6 0.1 2.7e-07 30.9 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMD62734.1 - 2.6e-06 26.8 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Tegument_dsDNA PF12818.2 EMD62735.1 - 0.034 13.0 0.1 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Orexin PF02072.10 EMD62737.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prepro-orexin BNR_2 PF13088.1 EMD62738.1 - 3.8e-05 23.1 0.4 0.014 14.7 0.1 2.3 1 1 0 2 2 2 2 BNR repeat-like domain Imm32 PF15579.1 EMD62738.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 32 BNR PF02012.15 EMD62738.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat WSC PF01822.14 EMD62739.1 - 1.6e-13 50.4 5.9 1.6e-13 50.4 4.1 2.4 2 0 0 2 2 2 1 WSC domain Asp PF00026.18 EMD62740.1 - 4.3e-35 121.4 0.0 5.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMD62740.1 - 1.5e-06 28.5 0.1 0.0019 18.6 0.1 3.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EMD62740.1 - 0.021 14.3 0.1 0.1 12.1 0.0 2.4 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMD62740.1 - 0.06 13.1 0.0 0.29 10.9 0.0 2.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TRAP_alpha PF03896.11 EMD62740.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_A2E PF12382.3 EMD62740.1 - 0.19 11.5 0.1 0.58 9.9 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon peptidase Mgm101p PF06420.7 EMD62743.1 - 0.052 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Glyco_hydro_3 PF00933.16 EMD62745.1 - 1.5e-80 270.3 0.0 2.1e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD62745.1 - 3.6e-41 141.1 0.0 6.8e-41 140.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD62745.1 - 5.8e-22 77.4 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain RTA1 PF04479.8 EMD62746.1 - 2.1e-54 184.3 13.9 2.7e-54 184.0 9.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Glyco_transf_28 PF03033.15 EMD62747.1 - 5.3e-21 74.8 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMD62747.1 - 0.0018 16.8 0.0 0.0037 15.8 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Zn_clus PF00172.13 EMD62748.1 - 1.1e-06 28.4 9.2 1.8e-06 27.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD62748.1 - 6.1e-06 25.0 0.3 9e-06 24.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 EMD62749.1 - 0.00091 18.8 0.1 0.00091 18.8 0.1 1.8 2 1 1 3 3 3 1 F-box-like Ank_5 PF13857.1 EMD62749.1 - 0.065 13.5 0.4 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD62750.1 - 2.6e-30 104.5 3.2 5.7e-18 65.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD62750.1 - 1.8e-27 93.7 2.6 7.2e-07 28.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMD62750.1 - 8.3e-18 64.4 0.0 1e-07 32.2 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD62750.1 - 7.7e-14 51.4 0.7 0.00016 21.7 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD62750.1 - 1e-12 46.9 0.2 0.032 14.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat RVP PF00077.15 EMD62750.1 - 0.012 15.5 0.1 20 5.1 0.0 3.1 3 1 0 3 3 3 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EMD62750.1 - 0.029 14.8 0.1 11 6.6 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease DUF1843 PF08898.5 EMD62750.1 - 0.05 13.6 4.1 0.91 9.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Nitro_FeMo-Co PF02579.12 EMD62750.1 - 0.097 12.7 2.3 0.44 10.6 0.3 2.1 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor KR PF08659.5 EMD62751.1 - 9.4e-41 139.4 0.1 8.3e-39 133.1 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EMD62751.1 - 1.6e-28 99.7 0.0 1.6e-27 96.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMD62751.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EMD62751.1 - 0.0029 17.3 0.0 0.0049 16.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 EMD62751.1 - 0.12 12.8 0.4 1.3 9.5 0.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Aminotran_1_2 PF00155.16 EMD62752.1 - 4.6e-32 111.3 0.1 1e-28 100.3 0.0 2.5 3 0 0 3 3 3 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMD62752.1 - 0.0035 16.5 0.0 0.55 9.3 0.0 2.8 2 1 0 2 2 2 2 Beta-eliminating lyase Fe-ADH PF00465.14 EMD62753.1 - 1e-14 53.9 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Condensation PF00668.15 EMD62754.1 - 1.1e-11 44.1 0.0 1.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EMD62755.1 - 4.6e-64 216.7 0.0 6.7e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMD62755.1 - 4.1e-60 203.3 1.5 5.2e-60 203.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EMD62755.1 - 1.6e-58 198.2 0.0 2.4e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMD62755.1 - 8.9e-55 185.1 1.5 2e-54 183.9 0.5 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMD62755.1 - 6.5e-44 149.7 0.5 1.6e-43 148.5 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD62755.1 - 2.8e-35 120.7 0.0 6.7e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMD62755.1 - 2e-17 63.4 0.0 9.9e-17 61.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMD62755.1 - 2.2e-14 53.1 0.0 6.2e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMD62755.1 - 6.1e-12 45.5 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD62755.1 - 4.8e-10 40.4 0.0 1.9e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EMD62755.1 - 1.8e-09 37.3 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62755.1 - 2.7e-08 34.3 0.0 8.9e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62755.1 - 3.5e-08 33.8 0.0 2.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EMD62755.1 - 2.8e-07 30.2 0.2 6.6e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMD62755.1 - 6.9e-06 26.2 2.7 9.4e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EMD62755.1 - 0.0012 17.9 0.1 0.0024 16.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 EMD62755.1 - 0.027 15.3 0.0 0.35 11.7 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain 3Beta_HSD PF01073.14 EMD62755.1 - 0.084 11.5 0.0 0.21 10.2 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 EMD62755.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EMD62756.1 - 1.5e-65 221.5 0.0 2.2e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMD62756.1 - 1.7e-23 83.2 0.0 3.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD62756.1 - 3.1e-19 69.4 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMD62756.1 - 1.8e-09 38.1 0.0 4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Desulfoferrod_N PF06397.7 EMD62756.1 - 0.084 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain NAD_binding_6 PF08030.7 EMD62756.1 - 0.21 11.4 0.0 0.78 9.6 0.0 1.8 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Fungal_trans PF04082.13 EMD62757.1 - 2.4e-06 26.6 0.2 7e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MAPEG PF01124.13 EMD62758.1 - 2.3e-20 72.5 0.4 2.5e-20 72.3 0.3 1.0 1 0 0 1 1 1 1 MAPEG family HTH_psq PF05225.11 EMD62759.1 - 1.9e-07 30.4 0.1 2.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Mga PF05043.8 EMD62759.1 - 0.091 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Mga helix-turn-helix domain p450 PF00067.17 EMD62761.1 - 1.2e-75 254.8 0.0 1.6e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Waikav_capsid_1 PF12264.3 EMD62762.1 - 0.036 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Mucin PF01456.12 EMD62762.1 - 0.077 12.7 1.1 0.091 12.5 0.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DDE_1 PF03184.14 EMD62763.1 - 1.8e-08 33.8 0.0 1.9e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3820 PF12843.2 EMD62763.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Cyclin PF08613.6 EMD62764.1 - 5.6e-12 46.3 0.0 1.4e-11 44.9 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMD62764.1 - 1.2e-08 34.5 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_39 PF01229.12 EMD62765.1 - 0.075 11.4 0.1 0.098 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 p450 PF00067.17 EMD62766.1 - 1.9e-57 194.8 0.0 5.1e-57 193.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.16 EMD62767.1 - 0.087 12.7 14.4 0.18 11.7 10.0 1.6 1 1 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.12 EMD62767.1 - 0.15 12.3 13.5 0.29 11.4 9.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Rib_recp_KP_reg PF05104.7 EMD62767.1 - 5.3 7.5 14.4 1.5 9.3 7.6 1.9 2 1 0 2 2 2 0 Ribosome receptor lysine/proline rich region DUF4234 PF14018.1 EMD62768.1 - 0.2 11.4 4.4 0.16 11.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) FlaC_arch PF05377.6 EMD62769.1 - 0.16 11.8 1.4 0.62 9.9 0.1 2.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 EMD62769.1 - 3.9 7.5 7.3 27 4.8 4.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EMD62770.1 - 0.011 15.3 3.4 0.013 15.0 2.4 1.1 1 0 0 1 1 1 0 IncA protein MerR-DNA-bind PF09278.6 EMD62770.1 - 0.55 10.6 5.8 0.58 10.5 3.2 1.6 2 0 0 2 2 2 0 MerR, DNA binding HOOK PF05622.7 EMD62772.1 - 0.0016 16.3 0.2 0.002 16.0 0.2 1.1 1 0 0 1 1 1 1 HOOK protein GDPD PF03009.12 EMD62772.1 - 0.048 13.1 0.4 0.13 11.7 0.2 1.6 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family RILP PF11461.3 EMD62772.1 - 2.2 8.4 5.2 12 6.1 3.6 2.2 1 1 0 1 1 1 0 Rab interacting lysosomal protein GtrA PF04138.9 EMD62773.1 - 0.076 12.9 0.0 0.08 12.8 0.0 1.0 1 0 0 1 1 1 0 GtrA-like protein NAD_binding_4 PF07993.7 EMD62775.1 - 0.022 13.7 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 EMD62775.1 - 0.022 13.4 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_S8 PF00082.17 EMD62777.1 - 5.4e-18 65.1 0.1 6.4e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Subtilase family FAD_binding_4 PF01565.18 EMD62778.1 - 9.4e-21 73.7 0.1 2.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD62778.1 - 0.016 15.1 0.2 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Catalase PF00199.14 EMD62779.1 - 1.3e-145 484.9 2.4 1.7e-145 484.5 1.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMD62779.1 - 1.9e-09 37.2 0.1 3.9e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Kelch_5 PF13854.1 EMD62780.1 - 1.9e-12 46.8 4.7 5.2e-10 39.0 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EMD62780.1 - 4.1e-06 26.7 2.0 0.00059 19.9 0.2 4.0 3 0 0 3 3 3 1 Galactose oxidase, central domain KdpA PF03814.10 EMD62780.1 - 0.00016 19.8 0.0 0.00023 19.3 0.0 1.1 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Kelch_4 PF13418.1 EMD62780.1 - 0.0031 17.2 3.5 0.03 14.0 0.1 3.5 3 1 1 4 4 4 1 Galactose oxidase, central domain DUF1517 PF07466.6 EMD62780.1 - 0.17 10.8 1.3 0.3 10.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MFS_1 PF07690.11 EMD62781.1 - 1.9e-12 46.5 31.6 1.9e-12 46.5 21.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD62781.1 - 9.4e-08 31.6 2.5 9.4e-08 31.6 1.7 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.10 EMD62781.1 - 1e-05 24.4 0.3 1e-05 24.4 0.2 2.1 3 0 0 3 3 3 1 PUCC protein Sugar_tr PF00083.19 EMD62781.1 - 0.0019 16.8 8.9 0.0049 15.5 5.9 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter DAO PF01266.19 EMD62782.1 - 2.3e-53 181.3 0.3 2.8e-53 181.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD62782.1 - 3.2e-07 30.6 0.1 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD62782.1 - 0.00076 18.4 0.1 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD62782.1 - 0.011 15.7 0.6 0.029 14.4 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD62782.1 - 0.012 15.3 3.6 0.058 13.1 0.2 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMD62782.1 - 0.016 14.3 0.5 0.051 12.6 0.1 2.0 2 1 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EMD62782.1 - 0.063 11.7 0.6 0.16 10.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 EMD62783.1 - 4.3e-26 91.3 0.1 7.9e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62783.1 - 5.1e-07 29.4 10.9 1.1e-06 28.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 EMD62784.1 - 7.2e-29 101.2 0.0 8.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DAO PF01266.19 EMD62785.1 - 5.8e-37 127.4 0.3 7.7e-37 127.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62785.1 - 2.3e-05 24.3 0.0 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD62785.1 - 0.0016 17.6 0.0 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EMD62785.1 - 0.0054 16.8 0.0 0.077 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD62785.1 - 0.017 14.8 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMD62785.1 - 0.018 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD62785.1 - 0.035 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Latarcin PF10279.4 EMD62785.1 - 0.17 12.0 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Latarcin precursor Methyltransf_23 PF13489.1 EMD62786.1 - 1.2e-20 73.8 0.1 2.5e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62786.1 - 7.1e-12 45.6 0.0 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD62786.1 - 9.9e-09 35.5 0.0 6.9e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62786.1 - 3e-08 34.2 0.0 3.9e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD62786.1 - 2.5e-07 30.3 0.0 3.8e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD62786.1 - 5.1e-05 22.4 0.0 0.0003 19.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMD62786.1 - 0.0035 16.7 0.0 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EMD62786.1 - 0.0047 16.0 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EMD62786.1 - 0.0062 16.0 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMD62786.1 - 0.0084 16.4 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD62786.1 - 0.022 14.7 0.0 0.067 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EMD62786.1 - 0.031 14.2 0.0 0.097 12.6 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EMD62786.1 - 0.049 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMD62786.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_3 PF01494.14 EMD62787.1 - 3e-20 72.6 3.5 4.2e-12 45.7 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD62787.1 - 6.4e-07 28.6 0.6 2e-06 26.9 0.4 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62787.1 - 2.8e-06 27.2 0.2 8.6e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD62787.1 - 3.4e-05 22.8 0.2 7.1e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMD62787.1 - 0.0083 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMD62787.1 - 0.0094 16.3 0.4 0.023 15.1 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD62787.1 - 0.024 14.5 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62787.1 - 0.12 11.2 0.4 0.29 10.0 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD62787.1 - 0.16 12.0 1.1 0.63 10.0 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 EMD62789.1 - 2.8e-25 88.2 3.5 4.5e-25 87.5 2.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD62789.1 - 2.1e-18 66.1 0.0 3.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD62789.1 - 3.1e-05 24.8 0.0 5.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD62789.1 - 0.00066 18.8 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMD62789.1 - 0.0044 17.1 0.0 0.014 15.5 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMD62789.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Nucleoplasmin PF03066.10 EMD62790.1 - 0.016 14.7 13.1 0.025 14.1 9.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EMD62790.1 - 0.13 12.1 5.4 0.29 10.9 3.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 EMD62790.1 - 2.9 5.6 15.5 3.7 5.3 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMD62790.1 - 3.5 5.9 15.2 4.9 5.5 10.5 1.2 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 EMD62790.1 - 5.7 6.1 20.2 9.3 5.4 14.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EMD62790.1 - 9.1 5.3 11.9 14 4.7 8.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region YqfQ PF14181.1 EMD62790.1 - 10 6.1 6.6 19 5.2 4.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein p450 PF00067.17 EMD62791.1 - 1.4e-68 231.5 0.0 1.7e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 EMD62792.1 - 5.3e-16 58.5 0.0 7.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD62792.1 - 5.9e-16 58.7 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD62792.1 - 7.7e-16 58.6 0.0 1.9e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD62792.1 - 3.8e-15 56.0 0.0 6.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD62792.1 - 1.9e-14 53.9 0.0 3.6e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD62792.1 - 4.3e-14 52.5 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD62792.1 - 2e-07 31.0 0.0 7.1e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMD62792.1 - 2.1e-07 30.5 0.0 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EMD62792.1 - 9.5e-06 24.8 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EMD62792.1 - 2.6e-05 23.5 0.0 5.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase TehB PF03848.9 EMD62792.1 - 9.1e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.6 EMD62792.1 - 0.0039 16.6 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.13 EMD62792.1 - 0.036 13.3 0.0 0.16 11.2 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EMD62792.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EMD62792.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EMD62792.1 - 0.054 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 EMD62792.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RhoGAP PF00620.22 EMD62793.1 - 5.4e-37 126.7 1.3 1.3e-36 125.5 0.3 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EMD62793.1 - 4.9e-27 93.7 36.7 3.4e-12 46.2 4.0 5.1 5 0 0 5 5 5 4 LIM domain DUF1708 PF08101.6 EMD62793.1 - 0.028 13.2 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) XhlA PF10779.4 EMD62793.1 - 6.2 6.8 5.7 8.3 6.4 1.2 2.7 2 0 0 2 2 2 0 Haemolysin XhlA RNA_pol_Rpb4 PF03874.11 EMD62794.1 - 8.9e-16 57.9 0.4 1.1e-15 57.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tyrosinase PF00264.15 EMD62795.1 - 2e-42 145.8 1.9 2.7e-42 145.4 1.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase LANC_like PF05147.8 EMD62796.1 - 1.3e-28 99.6 0.0 1.4e-27 96.2 0.0 2.1 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein CT47 PF15623.1 EMD62799.1 - 0.048 13.3 0.9 0.055 13.1 0.6 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 GKAP PF03359.8 EMD62799.1 - 0.15 11.6 1.6 0.15 11.6 1.1 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Clr5 PF14420.1 EMD62800.1 - 9.2e-10 38.2 0.5 1.6e-09 37.4 0.1 1.6 2 0 0 2 2 2 1 Clr5 domain Ank_2 PF12796.2 EMD62800.1 - 0.003 17.8 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD62800.1 - 0.013 15.9 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD62801.1 - 1e-38 131.5 9.9 3.9e-19 68.7 0.8 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD62801.1 - 2.8e-35 120.0 7.5 4.8e-14 52.4 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD62801.1 - 2.6e-28 95.2 2.8 2e-07 30.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.25 EMD62801.1 - 1.2e-27 94.2 15.4 6.7e-09 35.1 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EMD62801.1 - 1.7e-20 72.5 8.9 1.1e-05 25.5 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) PPR_3 PF13812.1 EMD62801.1 - 0.0043 17.2 5.3 27 5.3 0.0 4.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Fil_haemagg_2 PF13332.1 EMD62801.1 - 0.025 14.3 1.3 0.032 14.0 0.9 1.3 1 0 0 1 1 1 0 Haemagluttinin repeat Shigella_OspC PF06128.6 EMD62801.1 - 0.03 13.8 0.1 0.39 10.1 0.0 2.1 1 1 0 2 2 2 0 Shigella flexneri OspC protein DUF1843 PF08898.5 EMD62801.1 - 0.28 11.2 6.5 6 6.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) DUF2984 PF11203.3 EMD62801.1 - 1.2 9.3 6.6 0.49 10.5 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) APH PF01636.18 EMD62802.1 - 9.5e-11 41.8 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMD62802.1 - 0.0011 17.7 0.1 0.0019 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EMD62802.1 - 0.033 13.3 0.1 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EMD62802.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase p450 PF00067.17 EMD62803.1 - 1.5e-29 102.8 0.0 2e-24 85.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 polyprenyl_synt PF00348.12 EMD62804.1 - 1.6e-12 46.8 0.0 2.1e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APH PF01636.18 EMD62805.1 - 7.5e-13 48.7 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMD62805.1 - 0.00039 19.1 0.0 0.00062 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) 2OG-FeII_Oxy_2 PF13532.1 EMD62807.1 - 7.2e-28 97.7 0.0 8.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EMD62808.1 - 1.9e-16 59.7 0.0 3.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD62808.1 - 4e-07 29.8 12.0 7.7e-07 28.9 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EMD62808.1 - 0.11 12.1 1.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 adh_short PF00106.20 EMD62811.1 - 2.1e-12 47.2 0.0 2.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD62811.1 - 0.0002 21.0 0.0 0.00028 20.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD62811.1 - 0.00038 20.2 0.3 0.00069 19.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EMD62811.1 - 0.00055 19.7 0.0 0.00074 19.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase OKR_DC_1_N PF03709.10 EMD62811.1 - 0.0072 16.3 0.1 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain DUF2493 PF10686.4 EMD62811.1 - 0.096 12.2 0.1 0.34 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Pirin PF02678.11 EMD62813.1 - 3.5e-32 110.4 0.0 9.5e-32 109.0 0.0 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EMD62813.1 - 8.6e-28 96.4 0.0 5.9e-26 90.5 0.0 2.4 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMD62813.1 - 1.2e-09 37.4 0.9 4.7e-06 26.0 0.6 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMD62813.1 - 0.0009 18.5 0.3 0.67 9.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Dus PF01207.12 EMD62815.1 - 1.1e-46 159.0 0.0 4.5e-46 157.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ADH_zinc_N PF00107.21 EMD62816.1 - 1.4e-20 73.1 0.0 2.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD62816.1 - 5.8e-08 33.6 0.0 1.4e-07 32.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 EMD62816.1 - 0.15 11.2 0.0 0.81 8.8 0.0 1.9 1 1 1 2 2 2 0 PhoH-like protein RNA_pol_Rbc25 PF08292.7 EMD62817.1 - 1.1e-35 122.4 1.0 1.6e-35 121.9 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EMD62817.1 - 3.6e-15 55.8 0.0 6.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMD62817.1 - 0.0034 17.4 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain NUFIP1 PF10453.4 EMD62818.1 - 3e-13 49.0 0.1 3e-13 49.0 0.1 2.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EMD62818.1 - 6.8e-05 22.4 1.1 0.00012 21.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PI-PLC-X PF00388.14 EMD62819.1 - 3.2e-61 204.9 0.0 4.8e-61 204.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMD62819.1 - 2.9e-35 120.7 0.0 5e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EMD62819.1 - 0.0042 16.9 0.2 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 C2 domain Arteri_nucleo PF01481.11 EMD62820.1 - 0.33 11.0 2.9 0.75 9.9 1.1 2.4 2 1 0 2 2 2 0 Arterivirus nucleocapsid protein Glyco_transf_34 PF05637.7 EMD62821.1 - 9.1e-14 51.5 0.0 7e-09 35.5 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EMD62821.1 - 0.02 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 HlyIII PF03006.15 EMD62823.1 - 1.8e-50 171.4 22.7 2.1e-50 171.1 15.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EMD62823.1 - 0.0076 16.1 3.1 0.071 13.0 1.2 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) YcxB PF14317.1 EMD62823.1 - 0.034 13.3 0.1 0.072 12.3 0.1 1.5 1 0 0 1 1 1 0 YcxB-like protein ABM PF03992.11 EMD62824.1 - 5.3e-14 52.0 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Glyco_hydro_3 PF00933.16 EMD62825.1 - 9e-62 208.7 0.0 1.3e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD62825.1 - 8.5e-40 136.6 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain p450 PF00067.17 EMD62825.1 - 3.1e-12 45.7 0.1 4.9e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fn3-like PF14310.1 EMD62825.1 - 2.3e-06 27.4 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lactamase_B PF00753.22 EMD62827.1 - 4e-07 29.8 0.3 6.5e-07 29.2 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD62827.1 - 0.00057 19.4 1.0 0.00085 18.9 0.7 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD62827.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain COesterase PF00135.23 EMD62828.1 - 2e-62 211.6 0.0 2.6e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD62828.1 - 0.0001 21.9 1.1 0.0016 18.0 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold NAD_binding_10 PF13460.1 EMD62829.1 - 5.3e-21 75.4 0.0 8.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EMD62829.1 - 0.0043 16.5 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.9 EMD62829.1 - 0.038 13.3 0.0 0.081 12.3 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_11 PF14833.1 EMD62830.1 - 5.2e-29 100.7 0.0 7.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EMD62830.1 - 2.5e-10 40.4 0.0 4.2e-05 23.4 0.0 2.2 1 1 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_trans PF01144.18 EMD62832.1 - 7.3e-96 319.5 4.4 6.9e-56 188.8 0.4 2.3 2 0 0 2 2 2 2 Coenzyme A transferase Fe-ADH PF00465.14 EMD62832.1 - 6.3e-67 225.7 0.4 9.3e-67 225.2 0.3 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMD62832.1 - 3.5e-20 72.3 0.1 7.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Thiolase_N PF00108.18 EMD62833.1 - 1.3e-77 260.3 0.2 6.9e-77 257.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD62833.1 - 8.7e-43 144.6 0.1 7.6e-42 141.6 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMD62833.1 - 3.8e-05 23.3 0.4 9.8e-05 21.9 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Lyase_1 PF00206.15 EMD62834.1 - 1.3e-44 152.6 0.0 3.3e-44 151.3 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EMD62834.1 - 3.2e-23 81.5 0.0 2.6e-21 75.3 0.0 2.7 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HgmA PF04209.8 EMD62835.1 - 1.8e-128 428.6 0.0 2e-128 428.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CoA_transf_3 PF02515.12 EMD62836.1 - 3.9e-59 199.1 0.6 5.1e-59 198.7 0.4 1.1 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.13 EMD62837.1 - 1.9e-12 46.6 0.4 4.6e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMD62837.1 - 1.3e-05 25.2 18.1 0.0085 16.3 4.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD62837.1 - 2.5e-05 24.3 14.1 7.7e-05 22.7 5.7 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD62837.1 - 0.011 15.9 13.4 0.05 13.9 1.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EMD62837.1 - 0.064 13.4 21.5 0.074 13.2 1.0 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD62837.1 - 0.14 12.3 14.7 0.39 10.9 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 EMD62837.1 - 0.46 10.5 3.3 0.99 9.4 2.3 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EMD62837.1 - 1.2 9.1 7.0 1.3 9.0 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.17 EMD62838.1 - 1.1e-70 238.5 0.0 1.4e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1155 PF06633.6 EMD62838.1 - 0.0079 15.4 0.1 0.022 13.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1155) LIM_bind PF01803.11 EMD62838.1 - 0.045 12.8 0.6 0.079 12.0 0.4 1.3 1 0 0 1 1 1 0 LIM-domain binding protein DUF924 PF06041.6 EMD62839.1 - 2.3e-42 144.8 0.0 3.9e-42 144.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HSCB_C PF07743.8 EMD62843.1 - 1.5e-18 67.0 9.2 1.5e-18 67.0 6.4 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EMD62843.1 - 1.2e-10 40.9 0.2 3.2e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4570 PF15134.1 EMD62843.1 - 0.00067 19.4 1.2 0.00067 19.4 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) DUF2999 PF11212.3 EMD62843.1 - 0.2 11.7 0.8 13 5.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) adh_short PF00106.20 EMD62844.1 - 3.4e-12 46.5 0.1 7.5e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62844.1 - 7.1e-11 42.3 0.0 1.8e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62844.1 - 0.00049 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD62844.1 - 0.1 12.6 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding dCMP_cyt_deam_1 PF00383.17 EMD62845.1 - 6.6e-09 35.3 0.4 1.1e-08 34.5 0.2 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EMD62845.1 - 0.015 14.6 1.9 0.39 10.0 0.1 2.1 1 1 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases FAD_binding_3 PF01494.14 EMD62846.1 - 3.1e-17 62.6 0.0 8.9e-10 38.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD62846.1 - 2e-09 36.8 5.3 0.00037 19.5 0.4 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62846.1 - 0.00015 21.6 1.6 0.00059 19.8 1.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD62846.1 - 0.00032 19.6 6.4 0.00039 19.3 3.4 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD62846.1 - 0.00066 18.2 1.6 0.0098 14.3 1.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMD62846.1 - 0.0011 18.9 0.2 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD62846.1 - 0.0027 16.8 0.4 0.0054 15.8 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMD62846.1 - 0.0081 15.2 3.2 0.014 14.5 2.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMD62846.1 - 0.012 14.4 1.8 0.017 14.0 1.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMD62846.1 - 0.029 14.4 0.3 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD62846.1 - 0.044 12.3 4.0 0.091 11.3 0.4 2.1 1 1 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EMD62846.1 - 0.065 12.1 4.8 0.57 9.0 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMD62846.1 - 0.072 13.5 2.1 0.27 11.6 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD62846.1 - 0.08 11.9 1.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EMD62846.1 - 0.14 11.6 0.2 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMD62846.1 - 0.28 10.7 2.0 0.51 9.9 1.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EMD62846.1 - 0.82 9.4 5.2 23 4.7 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Amidase PF01425.16 EMD62847.1 - 2e-84 284.0 0.0 2.3e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EMD62848.1 - 2.1e-79 267.1 0.0 2.6e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMD62848.1 - 1.2e-40 138.8 0.0 2.2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EMD62848.1 - 8.3e-05 22.5 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD62848.1 - 0.00049 18.6 0.1 0.001 17.6 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMD62848.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMD62848.1 - 0.0024 17.9 0.1 0.0055 16.8 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD62848.1 - 0.0033 16.4 0.2 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMD62848.1 - 0.0064 15.4 0.0 0.14 10.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD62848.1 - 0.0089 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD62848.1 - 0.0098 16.2 0.0 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD62848.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Ald_Xan_dh_C2 PF02738.13 EMD62849.1 - 5.4e-183 609.2 0.0 7.4e-183 608.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMD62849.1 - 6.8e-39 133.0 0.0 1.4e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EMD62849.1 - 4.5e-34 116.4 0.0 3.4e-33 113.6 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EMD62849.1 - 6.9e-32 109.8 0.0 1.5e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EMD62849.1 - 5.6e-25 87.0 0.0 1.5e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EMD62849.1 - 6.4e-08 32.2 0.0 2.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Spherulin4 PF12138.3 EMD62850.1 - 6.9e-61 205.8 0.0 7.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 MFS_1 PF07690.11 EMD62851.1 - 4.4e-26 91.4 11.2 5.2e-26 91.2 5.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62851.1 - 0.0035 15.9 2.3 0.0035 15.9 1.6 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter HPP PF04982.8 EMD62851.1 - 5.2 6.9 8.8 2.6 7.8 3.5 2.3 2 1 0 2 2 2 0 HPP family GATase PF00117.23 EMD62852.1 - 2.7e-09 36.7 0.1 1.2e-08 34.5 0.1 1.8 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMD62852.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase C26 Beta_elim_lyase PF01212.16 EMD62853.1 - 2.2e-70 237.0 0.0 2.8e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMD62853.1 - 0.00053 18.3 0.0 0.001 17.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD62853.1 - 0.035 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II FSH1 PF03959.8 EMD62854.1 - 9.5e-30 103.6 0.0 1.2e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMD62854.1 - 4.1e-07 30.1 1.1 3e-06 27.2 0.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD62854.1 - 2.8e-05 23.9 0.0 5.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMD62854.1 - 0.00042 19.8 0.0 1.6 8.1 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMD62854.1 - 0.077 12.5 0.8 0.25 10.9 0.6 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold HET PF06985.6 EMD62855.1 - 1.1e-28 100.0 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glutaredoxin PF00462.19 EMD62856.1 - 7.2e-20 70.7 0.0 3.6e-18 65.3 0.0 2.6 2 1 1 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 EMD62856.1 - 3.7e-15 55.4 0.1 8.1e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMD62856.1 - 0.0044 17.1 0.1 0.52 10.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD62856.1 - 0.011 15.9 0.3 0.45 10.7 0.0 3.0 2 2 0 2 2 2 0 Thioredoxin-like domain TrbC_Ftype PF09673.5 EMD62856.1 - 0.023 14.2 0.0 0.078 12.5 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein ArsC PF03960.10 EMD62856.1 - 0.038 14.0 0.0 0.21 11.6 0.0 2.0 1 1 1 2 2 2 0 ArsC family GST_N_3 PF13417.1 EMD62856.1 - 0.1 12.8 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Brix PF04427.13 EMD62857.1 - 1.9e-34 118.9 1.6 2.6e-34 118.5 1.1 1.1 1 0 0 1 1 1 1 Brix domain MMS19_C PF12460.3 EMD62858.1 - 2.3e-102 342.8 1.2 2.3e-102 342.8 0.8 3.9 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EMD62858.1 - 2.1e-87 292.7 0.0 4e-86 288.5 0.0 2.7 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EMD62858.1 - 2e-05 24.8 9.7 0.27 11.5 0.1 6.8 6 2 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 EMD62858.1 - 0.0003 21.1 12.2 0.28 11.7 0.5 7.3 6 1 2 8 8 8 1 HEAT-like repeat HEAT PF02985.17 EMD62858.1 - 0.053 13.6 7.8 14 6.0 0.1 6.2 6 0 0 6 6 6 0 HEAT repeat THF_DHG_CYH PF00763.18 EMD62859.1 - 3.7e-16 59.2 0.0 5.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EMD62859.1 - 3.5e-13 48.9 0.0 1.7e-09 36.9 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF927 PF06048.6 EMD62859.1 - 0.029 13.6 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) F-box PF00646.28 EMD62860.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD62860.1 - 0.038 13.7 0.2 0.077 12.7 0.2 1.5 1 0 0 1 1 1 0 F-box-like SH3_9 PF14604.1 EMD62861.1 - 1.4e-30 104.6 3.4 2e-16 59.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMD62861.1 - 1.1e-24 85.5 3.2 6.2e-13 47.9 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EMD62861.1 - 1.8e-13 49.7 0.0 4.3e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EMD62861.1 - 9.6e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ATG16 PF08614.6 EMD62862.1 - 0.004 16.9 28.0 0.043 13.6 8.4 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF2803 PF10972.3 EMD62862.1 - 0.0092 15.5 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2803) DUF1664 PF07889.7 EMD62862.1 - 0.013 15.2 7.9 0.025 14.3 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 EMD62862.1 - 0.014 15.3 2.6 0.014 15.3 1.8 3.3 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Ribonucleas_3_2 PF11469.3 EMD62862.1 - 0.032 14.4 0.3 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease III Reo_sigmaC PF04582.7 EMD62862.1 - 0.1 11.7 9.9 0.32 10.1 1.8 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 EMD62862.1 - 0.31 11.4 10.4 1.5 9.2 0.6 3.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.6 EMD62862.1 - 0.47 10.3 11.6 0.9 9.4 0.4 3.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sporozoite_P67 PF05642.6 EMD62862.1 - 0.86 7.3 8.7 1.3 6.8 6.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GAS PF13851.1 EMD62862.1 - 1.2 8.2 22.4 1.6 7.8 5.3 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Kinesin-relat_1 PF12711.2 EMD62862.1 - 1.4 9.3 13.6 5.7 7.4 0.7 4.5 2 2 2 4 4 4 0 Kinesin motor Laminin_II PF06009.7 EMD62862.1 - 1.8 8.3 10.5 2.1 8.1 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF972 PF06156.8 EMD62862.1 - 1.8 8.9 24.0 1.3 9.3 2.1 4.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) ERM PF00769.14 EMD62862.1 - 2.6 7.5 35.4 0.31 10.5 11.8 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EMD62862.1 - 4 5.1 13.8 99 0.5 9.4 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EMD62862.1 - 4.7 6.7 17.2 1.4 8.4 1.0 4.0 3 2 2 5 5 5 0 Septum formation initiator DUF948 PF06103.6 EMD62862.1 - 6.6 6.6 8.2 18 5.2 0.3 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.4 EMD62862.1 - 7.4 5.6 17.0 2 7.5 4.2 2.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 BTB PF00651.26 EMD62863.1 - 4.2e-12 46.0 0.0 9.5e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CCDC14 PF15254.1 EMD62864.1 - 4.6 5.4 7.0 5.4 5.2 4.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DLH PF01738.13 EMD62865.1 - 0.00052 19.3 0.0 0.00074 18.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EMD62865.1 - 0.0048 15.8 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMD62865.1 - 0.022 14.0 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GPI-anchored PF10342.4 EMD62866.1 - 2.8e-16 59.7 1.0 2.8e-16 59.7 0.7 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.5 EMD62866.1 - 3 7.4 12.5 3.6 7.1 8.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF566 PF04484.7 EMD62866.1 - 7 6.0 17.4 9 5.7 12.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Med3 PF11593.3 EMD62866.1 - 9.5 5.3 16.7 12 5.0 11.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SET PF00856.23 EMD62868.1 - 5.4e-09 36.5 0.0 7.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 EMD62868.1 - 8.7e-09 35.1 11.0 8.7e-09 35.1 7.6 2.4 2 0 0 2 2 2 1 MYND finger PBP PF01161.15 EMD62870.1 - 8.7e-32 109.9 0.3 1.5e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Isochorismatase PF00857.15 EMD62870.1 - 1.3e-26 93.6 0.0 2.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Dynamin_M PF01031.15 EMD62871.1 - 4.5e-113 376.9 0.0 7.5e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EMD62871.1 - 6.4e-56 188.7 0.0 1.5e-55 187.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMD62871.1 - 3.3e-31 107.0 2.4 3.3e-31 107.0 1.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMD62871.1 - 0.00016 21.5 0.1 0.0011 18.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD62871.1 - 0.014 15.8 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EMD62871.1 - 0.11 11.7 0.1 8.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-CCHC_4 PF14392.1 EMD62871.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_E PF05680.7 EMD62872.1 - 1.9e-22 78.9 0.1 2.2e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 EMD62873.1 - 1.2e-16 59.8 6.6 6.9e-06 25.7 0.0 6.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Peptidase_S10 PF00450.17 EMD62877.1 - 2.9e-92 310.0 3.6 4.3e-92 309.4 2.5 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase RNase_H PF00075.19 EMD62878.1 - 7.3e-07 29.5 0.3 1.3e-06 28.7 0.1 1.6 2 0 0 2 2 2 1 RNase H Gryzun-like PF12742.2 EMD62878.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking ADH_N PF08240.7 EMD62886.1 - 1.2e-25 89.4 2.4 2.6e-25 88.3 0.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD62886.1 - 4.5e-22 77.9 0.0 6.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD62886.1 - 4.3e-05 24.4 0.0 7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD62886.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.1 EMD62886.1 - 0.023 14.3 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Pyr_redox_3 PF13738.1 EMD62886.1 - 0.048 13.7 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD62886.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EMD62886.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_3 PF07859.8 EMD62887.1 - 1.8e-53 181.2 0.0 2.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMD62887.1 - 2e-11 43.3 0.2 7.1e-11 41.5 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMD62887.1 - 3.4e-05 23.6 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EMD62887.1 - 7.1e-05 22.0 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Peptidase_S9 PF00326.16 EMD62887.1 - 0.00052 19.2 0.0 0.06 12.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2424 PF10340.4 EMD62887.1 - 0.0015 17.2 0.0 0.0025 16.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EMD62887.1 - 0.005 16.7 1.9 0.016 15.1 1.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMD62887.1 - 0.076 11.5 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 EMD62887.1 - 0.16 11.2 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Pyr_redox_3 PF13738.1 EMD62888.1 - 1.9e-21 77.0 0.0 3.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD62888.1 - 1.2e-13 50.1 0.0 8.9e-12 43.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD62888.1 - 8.4e-12 44.9 0.1 5.6e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMD62888.1 - 1.4e-10 40.6 0.0 6.6e-08 31.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD62888.1 - 3.4e-09 36.8 0.0 0.00056 19.8 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD62888.1 - 8.1e-06 25.1 0.9 0.0012 17.9 0.1 2.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 EMD62888.1 - 0.00021 21.6 5.9 0.19 12.1 0.0 3.8 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EMD62888.1 - 0.00025 20.9 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EMD62888.1 - 0.0008 18.8 0.3 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EMD62888.1 - 0.0019 17.1 1.7 0.017 14.0 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EMD62888.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EMD62888.1 - 0.012 15.8 0.1 0.23 11.7 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMD62888.1 - 0.014 15.1 5.0 0.59 9.8 0.1 4.0 2 2 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMD62888.1 - 0.022 13.9 0.0 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMD62888.1 - 0.033 14.2 0.0 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EMD62888.1 - 0.035 12.9 0.2 0.67 8.7 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMD62888.1 - 0.042 12.3 0.4 0.99 7.7 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.16 EMD62888.1 - 0.042 13.6 2.1 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 ThiF family FAD_binding_2 PF00890.19 EMD62888.1 - 0.067 12.0 0.2 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EMD62888.1 - 0.11 11.3 0.0 4.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Rep_fac_C PF08542.6 EMD62889.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Replication factor C C-terminal domain DDE_1 PF03184.14 EMD62890.1 - 1.2e-42 145.4 0.0 1.5e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD62890.1 - 1.5e-10 41.0 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EMD62891.1 - 2.5e-10 40.1 2.9 2.5e-10 40.0 2.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM238 PF15125.1 EMD62892.1 - 0.0046 16.8 0.2 0.005 16.7 0.1 1.2 1 0 0 1 1 1 1 TMEM238 protein family DUF1132 PF06575.7 EMD62893.1 - 0.083 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Pyr_redox_3 PF13738.1 EMD62894.1 - 2.1e-22 80.1 0.0 3.7e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD62894.1 - 6.4e-07 28.6 0.0 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD62894.1 - 1.4e-05 25.0 0.1 6.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMD62894.1 - 4.1e-05 21.9 0.0 0.00083 17.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EMD62894.1 - 0.00074 19.6 0.0 0.0048 16.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EMD62894.1 - 0.0013 18.7 0.0 0.5 10.2 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD62894.1 - 0.0029 17.3 0.0 5.9 6.6 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMD62894.1 - 0.18 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LpxK PF02606.9 EMD62896.1 - 0.013 14.4 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase SUR7 PF06687.7 EMD62897.1 - 6.8e-43 146.6 2.8 8.1e-43 146.4 1.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMD62897.1 - 8.3e-06 25.8 2.3 8.3e-06 25.8 1.6 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 P22_Tail-4 PF11650.3 EMD62897.1 - 0.011 15.3 0.2 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 P22 tail accessory factor DUF4389 PF14333.1 EMD62897.1 - 0.54 9.9 7.1 8.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Amastin PF07344.6 EMD62897.1 - 2.3 7.8 11.7 0.45 10.1 4.9 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein ABC2_membrane_3 PF12698.2 EMD62897.1 - 5.4 5.9 11.4 12 4.8 7.9 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4244 PF14029.1 EMD62898.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) EF-hand_1 PF00036.27 EMD62900.1 - 2.1e-28 95.4 1.7 2.5e-07 29.4 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMD62900.1 - 4.7e-24 83.7 1.6 1.4e-11 43.8 0.0 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 EMD62900.1 - 5.1e-24 84.1 4.3 4.7e-09 36.2 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EMD62900.1 - 1.2e-23 80.8 5.1 9.7e-05 21.9 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EMD62900.1 - 1.3e-16 59.0 7.9 0.0013 17.9 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 EMD62900.1 - 0.11 12.4 0.2 9.8 6.1 0.0 2.7 3 1 0 3 3 3 0 EF-hand domain GRP PF07172.6 EMD62900.1 - 0.52 10.8 10.9 0.81 10.2 7.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF1183 PF06682.7 EMD62900.1 - 7 6.1 8.0 10 5.6 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SRF-TF PF00319.13 EMD62901.1 - 4.4e-24 83.4 0.1 6.8e-24 82.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EMD62901.1 - 0.58 8.1 8.4 1.6 6.6 3.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Ycf1 PF05758.7 EMD62901.1 - 1.2 6.7 6.2 1.9 6.0 4.3 1.3 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 EMD62901.1 - 3.5 7.3 8.5 8 6.1 5.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF1708 PF08101.6 EMD62903.1 - 3.3e-157 523.6 0.0 4.2e-157 523.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF2205 PF10224.4 EMD62904.1 - 0.42 10.2 3.3 16 5.1 0.1 3.7 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) STT3 PF02516.9 EMD62906.1 - 9.8e-132 440.3 38.2 3.7e-127 425.2 24.8 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit zf-C2H2 PF00096.21 EMD62907.1 - 6.2e-05 23.0 33.8 0.19 12.1 0.6 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD62907.1 - 0.19 12.1 47.0 0.19 12.1 0.1 7.6 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD62908.1 - 0.0021 18.2 24.9 0.098 13.0 0.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type Toxin_11 PF07473.6 EMD62908.1 - 1.5 8.7 4.5 10 6.1 0.0 3.3 3 0 0 3 3 3 0 Spasmodic peptide gm9a SPC25 PF06703.6 EMD62911.1 - 1.5e-53 180.7 0.0 1.8e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EMD62912.1 - 7.8e-62 207.7 2.2 1e-61 207.3 1.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 zf-C2H2_4 PF13894.1 EMD62913.1 - 0.0065 16.7 14.7 0.16 12.3 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger DUF2890 PF11081.3 EMD62913.1 - 0.036 14.1 8.9 0.013 15.5 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) zf-TRAF PF02176.13 EMD62913.1 - 0.12 12.7 1.4 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger PRKCSH PF07915.8 EMD62914.1 - 5.3e-19 68.8 2.4 2e-18 66.9 0.1 3.0 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EMD62914.1 - 0.0025 17.3 0.7 0.011 15.2 0.0 2.3 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein HET PF06985.6 EMD62915.1 - 3.3e-28 98.5 0.0 9.2e-28 97.1 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EMD62916.1 - 3.5e-71 239.3 0.0 6e-71 238.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62916.1 - 6.3e-39 133.5 0.0 1.1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMD62916.1 - 2.5e-09 37.1 0.3 2.8e-08 33.7 0.1 2.5 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 EMD62916.1 - 7.8e-05 21.8 0.1 0.00013 21.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD62916.1 - 0.0035 16.3 0.0 0.007 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMD62916.1 - 0.023 14.0 0.3 0.043 13.1 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Lact-deh-memb PF09330.6 EMD62916.1 - 0.048 13.0 0.3 0.082 12.2 0.2 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding APH PF01636.18 EMD62916.1 - 0.055 13.1 0.1 5.6 6.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EMD62918.1 - 7.3e-60 202.3 0.0 1.8e-39 135.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD62918.1 - 3.2e-27 95.2 0.0 3.9e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EMD62918.1 - 3e-13 49.7 0.0 6.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EMD62918.1 - 6.1e-07 28.6 0.0 9.3e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMD62918.1 - 1.3e-06 28.2 0.0 0.0015 18.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 EMD62918.1 - 4.2e-05 23.2 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold Pkinase_C PF00433.19 EMD62918.1 - 0.037 14.5 0.1 0.037 14.5 0.1 3.3 3 0 0 3 3 3 0 Protein kinase C terminal domain PAS_9 PF13426.1 EMD62918.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain Kdo PF06293.9 EMD62918.1 - 0.11 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMD62918.1 - 0.41 9.4 0.1 0.77 8.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pex14_N PF04695.8 EMD62919.1 - 0.0001 22.3 3.0 0.00012 22.1 2.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM154 PF15102.1 EMD62919.1 - 0.0006 19.5 3.0 0.00084 19.0 2.1 1.3 1 1 0 1 1 1 1 TMEM154 protein family DUF3464 PF11947.3 EMD62919.1 - 0.002 17.6 2.0 0.0027 17.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) Dicty_REP PF05086.7 EMD62919.1 - 0.18 9.5 4.5 0.17 9.6 3.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.4 EMD62919.1 - 0.25 10.7 15.7 0.38 10.1 10.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MDFI PF15316.1 EMD62919.1 - 0.35 10.8 3.3 0.33 10.9 2.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DHHW PF14286.1 EMD62919.1 - 0.47 9.7 2.6 0.46 9.7 1.8 1.1 1 0 0 1 1 1 0 DHHW protein Rifin_STEVOR PF02009.11 EMD62919.1 - 0.71 9.4 6.4 1.1 8.7 4.4 1.3 1 1 0 1 1 1 0 Rifin/stevor family CAF-1_p150 PF11600.3 EMD62919.1 - 0.82 9.0 13.4 0.95 8.8 9.3 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FLO_LFY PF01698.11 EMD62919.1 - 1.1 8.0 4.1 1.3 7.8 2.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Dsh_C PF12316.3 EMD62919.1 - 1.5 8.8 10.2 1.8 8.6 7.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Kei1 PF08552.6 EMD62919.1 - 6 6.4 8.2 9.8 5.7 5.7 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Period_C PF12114.3 EMD62919.1 - 7.4 6.1 14.9 9.1 5.8 10.4 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 EMD62919.1 - 8.7 4.4 11.1 10 4.2 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2945 PF11160.3 EMD62920.1 - 9.4e-14 50.9 2.2 1.2e-13 50.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2945) Integrin_b_cyt PF08725.6 EMD62920.1 - 0.2 11.0 1.4 0.57 9.6 1.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Glyco_hydro_38 PF01074.17 EMD62921.1 - 1.5e-90 303.2 0.6 2.9e-90 302.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMD62921.1 - 1.9e-67 228.0 0.0 3e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMD62921.1 - 3.5e-27 94.4 0.0 7.3e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain SNARE PF05739.14 EMD62922.1 - 2e-06 27.3 2.0 2e-06 27.3 1.4 2.5 2 0 0 2 2 2 1 SNARE domain ATP-synt_E PF05680.7 EMD62922.1 - 0.1 12.5 0.4 0.1 12.5 0.2 2.5 3 0 0 3 3 3 0 ATP synthase E chain FUSC PF04632.7 EMD62922.1 - 1.7 6.9 6.5 2.3 6.5 4.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V-SNARE_C PF12352.3 EMD62922.1 - 3.7 7.7 7.3 4 7.5 0.5 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Epimerase PF01370.16 EMD62923.1 - 7.5e-58 195.7 0.0 9.6e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD62923.1 - 7.8e-24 84.0 0.0 1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMD62923.1 - 1.3e-20 73.3 0.0 1.8e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMD62923.1 - 2.6e-20 72.5 0.0 2.5e-19 69.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EMD62923.1 - 2.2e-17 62.8 0.1 2.2e-16 59.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMD62923.1 - 5.2e-06 26.4 0.1 5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMD62923.1 - 2.3e-05 24.4 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMD62923.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain p450 PF00067.17 EMD62924.1 - 3.6e-63 213.6 0.0 4.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tad PF13400.1 EMD62924.1 - 3 7.9 4.3 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like ketoacyl-synt PF00109.21 EMD62925.1 - 1.3e-75 254.2 0.1 5.1e-74 248.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD62925.1 - 6.2e-51 173.6 0.0 2.7e-50 171.5 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD62925.1 - 8.4e-31 106.2 0.3 2.3e-30 104.9 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMD62925.1 - 2.6e-12 46.8 0.4 7.2e-12 45.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 EMD62925.1 - 3.2e-11 42.9 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EMD62925.1 - 2.8e-05 23.2 0.1 6.3e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EMD62925.1 - 0.00062 19.5 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD62925.1 - 0.016 15.0 0.8 0.06 13.2 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lactamase_B PF00753.22 EMD62926.1 - 1.8e-22 79.9 0.1 2.4e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD62926.1 - 2e-05 24.2 0.1 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD62926.1 - 0.0025 17.5 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.6 EMD62927.1 - 5e-19 68.4 0.6 6.8e-19 67.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1772 PF08592.6 EMD62928.1 - 8.5e-12 44.9 2.2 1.3e-11 44.3 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) OpgC_C PF10129.4 EMD62928.1 - 0.34 9.5 4.7 0.36 9.4 3.3 1.1 1 0 0 1 1 1 0 OpgC protein Scytalone_dh PF02982.9 EMD62929.1 - 4.3e-59 198.6 0.2 4.9e-59 198.4 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMD62929.1 - 2.7e-06 27.3 0.9 4.4e-06 26.6 0.6 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EMD62929.1 - 0.014 15.3 0.8 0.37 10.8 0.5 2.2 1 1 0 1 1 1 0 SnoaL-like domain NAD_binding_10 PF13460.1 EMD62930.1 - 2.3e-17 63.6 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD62930.1 - 8.6e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EMD62930.1 - 4.5e-05 22.2 0.0 5.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD62930.1 - 7.6e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMD62930.1 - 0.017 15.4 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EMD62930.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMD62930.1 - 0.057 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EMD62931.1 - 2.5e-30 105.5 0.8 3.5e-30 105.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD62931.1 - 8.4e-28 97.7 0.0 1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD62931.1 - 3.5e-13 49.6 0.4 5.3e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62931.1 - 0.0016 17.9 1.2 0.0051 16.2 0.8 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EMD62931.1 - 0.025 13.7 0.1 0.037 13.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain B12-binding PF02310.14 EMD62931.1 - 0.088 12.6 1.1 0.18 11.6 0.4 1.7 2 0 0 2 2 2 0 B12 binding domain RQC PF09382.5 EMD62931.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 RQC domain ABC2_membrane PF01061.19 EMD62932.1 - 5.7e-85 283.7 46.6 2e-46 157.8 10.0 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMD62932.1 - 3.5e-37 127.7 0.0 7.1e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD62932.1 - 3.7e-21 74.7 0.1 4.3e-19 68.0 0.0 2.8 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EMD62932.1 - 1.9e-12 46.8 24.7 2.8e-07 29.9 6.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 EMD62932.1 - 6.9e-06 26.2 0.1 0.12 12.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD62932.1 - 3.2e-05 23.4 0.1 0.02 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EMD62932.1 - 3.4e-05 23.3 0.5 0.24 10.8 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMD62932.1 - 0.00022 21.1 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EMD62932.1 - 0.00044 20.2 1.1 0.4 10.6 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD62932.1 - 0.0011 18.9 0.4 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EMD62932.1 - 0.0014 17.8 0.2 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EMD62932.1 - 0.0019 17.9 0.0 0.085 12.5 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 EMD62932.1 - 0.002 17.6 0.9 0.081 12.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EMD62932.1 - 0.002 18.9 0.0 1.4 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD62932.1 - 0.0024 18.1 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD62932.1 - 0.0065 16.1 1.7 3.1 7.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 EMD62932.1 - 0.01 15.6 0.1 3.2 7.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ABC_trans_N PF14510.1 EMD62932.1 - 0.011 15.8 0.2 0.034 14.2 0.2 1.9 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal PduV-EutP PF10662.4 EMD62932.1 - 0.013 14.9 0.9 1.7 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMD62932.1 - 0.028 14.9 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EMD62932.1 - 0.052 13.7 0.2 10 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EMD62932.1 - 0.056 13.3 0.0 1.4 8.8 0.0 3.0 2 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EMD62932.1 - 0.088 12.4 1.1 4.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 OrfB_Zn_ribbon PF07282.6 EMD62932.1 - 0.14 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain T2SE PF00437.15 EMD62932.1 - 0.2 10.5 0.2 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Zn_clus PF00172.13 EMD62933.1 - 1.7e-05 24.6 18.8 1.7e-05 24.6 13.1 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.6 EMD62934.1 - 7e-21 74.9 0.1 9.2e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 EthD domain LacI PF00356.16 EMD62935.1 - 0.11 12.0 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family FAD_binding_3 PF01494.14 EMD62936.1 - 5e-71 239.6 0.0 6.3e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD62936.1 - 0.063 13.6 0.0 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EMD62937.1 - 1.7e-07 31.5 0.0 4.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD62937.1 - 1.1e-05 24.9 0.5 7.2e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMD62937.1 - 2.2e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD62937.1 - 9.9e-05 22.2 0.0 0.0063 16.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EMD62937.1 - 0.00023 21.2 0.0 0.0011 19.1 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PSI_PsaJ PF01701.13 EMD62937.1 - 0.04 13.6 0.2 5 6.9 0.0 2.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ Zot PF05707.7 EMD62937.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) OGG_N PF07934.7 EMD62938.1 - 7.3e-35 119.4 0.0 1.7e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EMD62938.1 - 1.1e-13 51.4 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMD62938.1 - 6.2e-05 22.4 0.0 0.00015 21.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EMD62939.1 - 1.8e-27 94.7 0.1 8.7e-11 41.3 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD62939.1 - 1.8e-15 56.6 0.0 0.00023 21.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD62939.1 - 3.5e-08 33.1 0.0 0.00038 20.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EMD62940.1 - 7.1e-15 55.3 0.1 9.8e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD62940.1 - 2.2e-08 33.9 0.2 3.4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD62940.1 - 0.066 12.6 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMD62940.1 - 0.12 12.5 0.1 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YcgR PF07317.7 EMD62940.1 - 0.13 12.0 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulator YcgR CotJA PF11007.3 EMD62941.1 - 1.6 8.4 4.4 0.6 9.7 1.2 1.7 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) Sugar_tr PF00083.19 EMD62943.1 - 3.8e-128 427.9 22.1 4.3e-128 427.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD62943.1 - 1.2e-22 80.0 24.3 1.2e-22 80.0 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily dUTPase PF00692.14 EMD62945.1 - 1.2e-36 124.9 0.0 1.5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase Pilus_PilP PF11356.3 EMD62945.1 - 5.2 7.3 7.1 1.9 8.7 0.1 2.5 3 0 0 3 3 3 0 Type IV pilus biogenesis Phos_pyr_kin PF08543.7 EMD62946.1 - 9.8e-10 38.0 0.0 1.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMD62946.1 - 5.2e-08 32.3 0.1 9.4e-06 24.9 0.0 2.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase PCNA_C PF02747.10 EMD62947.1 - 2.2e-53 179.5 0.0 6.7e-53 177.9 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EMD62947.1 - 1e-52 176.9 4.8 1.3e-52 176.6 2.3 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 EMD62947.1 - 1.6e-08 34.0 0.0 1.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EMD62947.1 - 0.00022 20.2 0.0 0.00065 18.7 0.0 1.8 1 1 1 2 2 2 1 Hus1-like protein Rab5ip PF07019.7 EMD62948.1 - 3.3e-23 81.6 5.5 4e-23 81.3 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sigma70_r4_2 PF08281.7 EMD62950.1 - 0.00086 18.7 0.1 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EMD62950.1 - 0.00095 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.11 EMD62950.1 - 0.021 14.1 0.2 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.1 EMD62950.1 - 0.034 14.2 0.1 0.14 12.3 0.0 2.0 1 1 0 1 1 1 0 Winged helix-turn helix Vezatin PF12632.2 EMD62951.1 - 5.6e-54 182.8 0.0 9.2e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes ADH_N PF08240.7 EMD62953.1 - 6.3e-25 87.0 1.8 1.1e-24 86.2 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD62953.1 - 1.2e-22 79.8 0.0 1.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD62953.1 - 0.0023 17.1 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CFEM PF05730.6 EMD62954.1 - 2.1e-15 56.3 13.9 3.4e-15 55.6 9.6 1.3 1 0 0 1 1 1 1 CFEM domain Pkinase_Tyr PF07714.12 EMD62954.1 - 0.19 10.7 1.7 3.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase PPR_2 PF13041.1 EMD62955.1 - 3.4e-12 46.1 0.7 0.0076 16.2 0.0 5.0 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.15 EMD62955.1 - 0.011 15.6 0.3 18 5.5 0.0 5.0 6 0 0 6 6 6 0 PPR repeat PPR_3 PF13812.1 EMD62955.1 - 0.02 15.1 5.1 37 4.9 0.0 6.1 7 0 0 7 7 7 0 Pentatricopeptide repeat domain MFS_1 PF07690.11 EMD62956.1 - 2.7e-49 167.7 36.6 3.6e-44 150.9 14.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD62956.1 - 2.7e-08 32.8 21.0 1.3e-07 30.5 14.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter F-box-like_2 PF13013.1 EMD62957.1 - 0.022 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain DHDPS PF00701.17 EMD62961.1 - 2.8e-41 141.0 0.0 3.5e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family F-box-like PF12937.2 EMD62964.1 - 1.3e-05 24.8 1.0 5.7e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like NOA36 PF06524.7 EMD62964.1 - 0.15 11.2 5.4 0.21 10.7 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EMD62964.1 - 1.6 8.2 12.7 2.9 7.3 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EMD62964.1 - 2.4 5.9 10.7 3.3 5.5 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EMD62964.1 - 8.6 5.4 6.8 17 4.4 4.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region LMBR1 PF04791.11 EMD62965.1 - 4.8e-19 68.2 4.7 5e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 LMBR1-like membrane protein Kei1 PF08552.6 EMD62965.1 - 0.0054 16.4 0.7 0.0054 16.4 0.5 3.4 2 2 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4234 PF14018.1 EMD62965.1 - 0.69 9.6 0.0 0.69 9.6 0.0 4.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4234) CPSF_A PF03178.10 EMD62966.1 - 1.3e-89 300.4 0.0 2.9e-89 299.3 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region DnaJ PF00226.26 EMD62967.1 - 9.5e-25 86.1 1.0 1.7e-24 85.3 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMD62967.1 - 2.9e-24 84.7 0.2 6.2e-21 74.0 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMD62967.1 - 1.6e-14 53.6 18.2 3.1e-14 52.7 12.6 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMD62967.1 - 0.062 12.9 9.5 0.09 12.4 1.4 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EMD62967.1 - 0.11 12.2 6.6 2.4 8.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 EMD62967.1 - 0.15 12.0 2.3 13 5.9 0.0 3.3 3 0 0 3 3 3 0 zinc-finger DUF1356 PF07092.7 EMD62967.1 - 0.25 10.5 0.6 16 4.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) DUF2614 PF11023.3 EMD62967.1 - 0.3 10.8 5.6 2.7 7.8 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Zn_Tnp_IS1595 PF12760.2 EMD62967.1 - 6.8 6.5 9.3 15 5.4 1.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain URO-D PF01208.12 EMD62968.1 - 6e-122 406.8 0.0 6.7e-122 406.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EMD62968.1 - 0.062 12.8 0.2 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Phloem filament protein PP1 MutS_V PF00488.16 EMD62969.1 - 2.4e-85 285.7 0.0 3.6e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD62969.1 - 4.5e-35 121.2 1.0 2.3e-34 118.9 0.6 2.3 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EMD62969.1 - 3.4e-19 68.9 0.0 8e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMD62969.1 - 2.5e-08 34.0 0.0 1.4e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMD62969.1 - 1.2e-05 25.3 1.5 2.5e-05 24.3 0.1 2.3 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.1 EMD62969.1 - 0.029 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMD62969.1 - 0.13 12.5 0.2 3 8.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Bromodomain PF00439.20 EMD62969.1 - 0.17 11.8 0.6 62 3.6 0.1 3.9 4 1 0 4 4 4 0 Bromodomain SnoaL_2 PF12680.2 EMD62971.1 - 5.1e-05 23.6 0.0 0.00024 21.4 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 EMD62971.1 - 0.00054 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase KilA-N PF04383.8 EMD62972.1 - 0.00031 20.3 0.0 0.0026 17.3 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Zn_clus PF00172.13 EMD62972.1 - 0.0056 16.5 10.1 0.012 15.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TipAS PF07739.8 EMD62973.1 - 0.01 16.1 0.8 0.025 14.8 0.5 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain CorA PF01544.13 EMD62973.1 - 0.26 10.3 2.5 0.17 10.8 0.4 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3659 PF12396.3 EMD62974.1 - 0 1051.0 191.9 1.8e-24 85.1 2.2 16.7 17 0 0 17 17 17 15 Protein of unknown function (DUF3659) Tape_meas_lam_C PF09718.5 EMD62974.1 - 1.4 8.9 32.5 0.02 14.8 2.5 5.5 3 1 2 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_fiber_C PF06820.7 EMD62974.1 - 1.7 8.8 14.7 9 6.5 0.0 7.1 9 0 0 9 9 9 0 Putative prophage tail fibre C-terminus DUF2422 PF10337.4 EMD62974.1 - 2.1 7.0 0.3 4.2 6.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) GSP_synth PF03738.9 EMD62974.1 - 4.7 7.5 14.5 95 3.3 0.0 9.1 11 1 0 11 11 11 0 Glutathionylspermidine synthase preATP-grasp AAA PF00004.24 EMD62976.1 - 7.9e-53 178.1 0.0 1.6e-44 151.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD62976.1 - 6.6e-09 36.6 0.0 0.0012 19.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD62976.1 - 8.1e-05 22.1 0.0 0.0007 19.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD62976.1 - 0.00016 20.8 0.0 0.00049 19.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD62976.1 - 0.00032 20.8 0.1 0.0067 16.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 EMD62976.1 - 0.00049 19.0 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EMD62976.1 - 0.0013 18.7 2.3 0.028 14.4 0.0 3.4 3 1 0 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EMD62976.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EMD62976.1 - 0.0022 18.1 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EMD62976.1 - 0.003 17.4 0.0 0.0075 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EMD62976.1 - 0.0049 15.6 0.0 0.0089 14.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMD62976.1 - 0.0072 16.0 0.0 0.027 14.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMD62976.1 - 0.011 15.9 0.0 0.094 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EMD62976.1 - 0.021 14.5 0.0 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMD62976.1 - 0.021 13.9 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EMD62976.1 - 0.022 13.8 0.3 0.069 12.2 0.0 1.9 3 0 0 3 3 2 0 KaiC AAA_33 PF13671.1 EMD62976.1 - 0.031 14.1 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EMD62976.1 - 0.037 13.2 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EMD62976.1 - 0.05 13.5 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AalphaY_MDB PF04611.7 EMD62976.1 - 0.068 13.0 0.2 0.2 11.5 0.0 1.9 2 0 0 2 2 1 0 Mating type protein A alpha Y mating type dependent binding region AAA_28 PF13521.1 EMD62976.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMD62976.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EMD62976.1 - 0.18 10.3 0.6 0.26 9.8 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase NB-ARC PF00931.17 EMD62976.1 - 0.38 9.5 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Abhydro_lipase PF04083.11 EMD62977.1 - 1.1e-17 63.1 0.0 4.5e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMD62977.1 - 8.2e-10 38.9 0.5 1.7e-09 37.9 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD62977.1 - 8.5e-06 25.4 0.1 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD62977.1 - 0.00016 21.4 0.0 0.00031 20.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EMD62977.1 - 0.048 12.9 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Tubulin PF00091.20 EMD62978.1 - 1.7e-66 224.1 0.0 2.3e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD62978.1 - 1.1e-42 145.0 0.0 1.7e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMD62978.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.13 EMD62979.1 - 1e-21 77.2 1.3 1.7e-21 76.5 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMD62979.1 - 0.00037 19.5 0.2 0.00083 18.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMD62979.1 - 0.00049 19.3 0.0 0.0013 17.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMD62979.1 - 0.0005 20.1 0.2 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMD62979.1 - 0.001 18.7 0.0 0.005 16.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DUF2648 PF10855.3 EMD62979.1 - 0.1 12.0 1.5 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) DUF4243 PF14027.1 EMD62980.1 - 6.9e-86 288.6 0.1 8.2e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AA_permease_2 PF13520.1 EMD62981.1 - 3.8e-43 147.6 53.1 4.8e-43 147.2 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD62981.1 - 4.2e-23 81.4 35.1 4.2e-23 81.4 24.3 1.8 2 0 0 2 2 2 1 Amino acid permease COX4 PF02936.9 EMD62981.1 - 0.16 11.7 0.6 22 4.7 0.6 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV AA_permease PF00324.16 EMD62982.1 - 4.8e-122 407.7 47.6 5.9e-122 407.4 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD62982.1 - 4.9e-29 101.1 52.6 6.6e-29 100.7 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_88 PF07470.8 EMD62983.1 - 1.3e-11 44.1 0.0 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4062 PF13271.1 EMD62983.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) CDP-OH_P_transf PF01066.16 EMD62984.1 - 1.9e-16 60.2 6.2 1.9e-16 60.2 4.3 2.3 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.19 EMD62985.1 - 3.9e-19 68.5 1.3 2.3e-18 66.0 0.5 2.5 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 EMD62985.1 - 2.6e-11 43.2 6.8 6e-06 25.6 0.7 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EMD62985.1 - 1.1e-05 25.0 4.7 3.7e-05 23.3 3.2 1.9 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 EMD62985.1 - 1.1 8.8 3.4 0.98 8.9 0.0 2.4 2 1 1 3 3 3 0 IncA protein Taxilin PF09728.4 EMD62985.1 - 2.4 7.1 7.4 3.6 6.5 0.3 2.5 2 1 0 2 2 2 0 Myosin-like coiled-coil protein ADK PF00406.17 EMD62986.1 - 4.9e-38 130.3 0.0 9.6e-21 74.2 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EMD62986.1 - 9.4e-14 50.7 0.0 1.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EMD62986.1 - 1.2e-05 25.5 0.0 0.00018 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD62986.1 - 4.6e-05 24.2 0.0 7.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD62986.1 - 0.017 15.0 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EMD62986.1 - 0.026 13.3 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 EMD62986.1 - 0.054 12.5 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin LETM1 PF07766.8 EMD62987.1 - 5.5e-107 356.7 0.0 9.6e-107 355.9 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EMD62987.1 - 4e-05 23.0 0.0 0.024 14.1 0.0 3.4 3 0 0 3 3 3 1 SAP domain HLH PF00010.21 EMD62987.1 - 0.049 13.3 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Peptidase_M76 PF09768.4 EMD62987.1 - 0.061 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase M76 family Reo_sigmaC PF04582.7 EMD62989.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EMD62989.1 - 2.1 7.9 4.3 0.39 10.2 0.1 1.9 3 0 0 3 3 3 0 IncA protein SPT2 PF08243.6 EMD62990.1 - 0.0078 16.5 19.5 0.024 14.9 13.5 1.8 1 1 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EMD62991.1 - 1.9e-27 95.4 11.5 2.2e-27 95.2 8.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EMD62992.1 - 5.5e-33 112.4 0.2 7.2e-33 112.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Prenyltransf PF01255.14 EMD62993.1 - 4.3e-08 32.5 0.0 2.4e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 EMD62994.1 - 4.6e-198 659.7 0.0 5.5e-198 659.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 PTR2 PF00854.16 EMD62997.1 - 1.2e-53 182.2 8.5 4.7e-31 107.9 2.1 2.2 1 1 1 2 2 2 2 POT family Cation_efflux PF01545.16 EMD62998.1 - 6.1e-79 265.0 10.4 1.4e-78 263.8 7.2 1.5 1 1 0 1 1 1 1 Cation efflux family Macoilin PF09726.4 EMD62998.1 - 0.042 12.1 6.6 0.046 12.0 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Ofd1_CTDD PF10637.4 EMD62999.1 - 1.5e-96 322.5 0.0 3.8e-89 298.3 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EMD62999.1 - 4.2e-14 52.8 0.0 1.8e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cut8_N PF14482.1 EMD62999.1 - 0.25 11.3 4.4 3.2 7.8 0.0 3.4 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Dynamitin PF04912.9 EMD63000.1 - 1.8e-33 115.9 14.5 5.8e-33 114.2 10.1 1.9 1 1 0 1 1 1 1 Dynamitin Prefoldin_2 PF01920.15 EMD63000.1 - 0.014 15.1 2.5 0.014 15.1 1.7 3.5 3 0 0 3 3 3 0 Prefoldin subunit Lectin_N PF03954.9 EMD63000.1 - 0.18 11.2 1.7 0.21 11.0 0.3 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain SlyX PF04102.7 EMD63000.1 - 1.2 9.5 12.1 4.5 7.7 1.0 4.8 3 2 2 5 5 5 0 SlyX Baculo_PEP_C PF04513.7 EMD63000.1 - 1.9 8.3 6.1 2.7 7.8 0.2 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GBP_C PF02841.9 EMD63000.1 - 9.5 5.3 16.1 0.027 13.6 3.1 2.3 2 1 1 3 3 3 0 Guanylate-binding protein, C-terminal domain P34-Arc PF04045.9 EMD63001.1 - 2.9e-102 341.0 0.4 3.5e-102 340.8 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EMD63001.1 - 0.002 17.5 0.1 0.0067 15.8 0.1 1.8 2 0 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.27 EMD63002.1 - 9.6e-71 231.3 30.2 5.2e-08 32.4 0.1 12.0 12 1 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 EMD63002.1 - 4.3e-21 74.8 0.2 6.8e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family BBS2_Mid PF14783.1 EMD63002.1 - 1.6e-07 31.0 3.0 1.6 8.5 0.0 7.8 5 2 3 8 8 8 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EMD63002.1 - 4.5e-06 25.1 8.0 0.13 10.3 0.0 5.8 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD63002.1 - 0.00013 20.8 5.1 0.95 8.1 0.1 5.7 2 2 1 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 EMD63002.1 - 0.00028 20.6 0.3 0.13 11.9 0.0 4.3 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EMD63002.1 - 0.035 13.2 0.2 6.3 5.8 0.0 3.4 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal COesterase PF00135.23 EMD63003.1 - 1.4e-58 198.9 0.0 1.8e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD63003.1 - 1.5e-07 31.2 0.1 1.6e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD63003.1 - 0.2 10.8 1.1 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DRMBL PF07522.9 EMD63004.1 - 1.1e-33 115.5 0.0 2.1e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMD63004.1 - 1.2e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMD63004.1 - 0.033 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Rad50_zn_hook PF04423.9 EMD63004.1 - 0.12 11.9 0.4 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Flavin_Reduct PF01613.13 EMD63005.1 - 0.19 11.5 2.7 0.26 11.1 1.9 1.2 1 0 0 1 1 1 0 Flavin reductase like domain SHD1 PF03983.7 EMD63008.1 - 2.7e-38 129.4 0.1 4.7e-38 128.6 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EMD63008.1 - 4.2e-37 125.3 7.2 1.2e-13 50.1 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EMD63008.1 - 1.7e-32 110.7 7.8 1.3e-11 43.8 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EMD63008.1 - 5.2e-27 93.1 0.0 1.2e-09 37.5 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EMD63008.1 - 0.00037 20.6 4.6 0.43 10.7 0.4 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 EMD63008.1 - 0.00038 20.4 27.3 0.00038 20.4 18.9 6.1 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) MFS_1 PF07690.11 EMD63009.1 - 7.1e-29 100.6 32.3 1.1e-28 99.9 22.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63009.1 - 8.5e-06 24.6 28.5 1.5e-05 23.7 19.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter GlpM PF06942.7 EMD63009.1 - 0.017 15.3 1.2 0.017 15.3 0.8 2.3 2 1 1 3 3 3 0 GlpM protein CBFB_NFYA PF02045.10 EMD63010.1 - 6.6e-30 103.4 3.1 1.6e-29 102.1 2.1 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cwf_Cwc_15 PF04889.7 EMD63010.1 - 0.093 12.4 5.2 0.19 11.4 3.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2106 PF09879.4 EMD63010.1 - 0.6 9.4 2.0 1.1 8.6 1.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) RRM_1 PF00076.17 EMD63011.1 - 1.4e-14 53.4 0.1 4.1e-10 39.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63011.1 - 9.8e-10 38.1 0.0 6.2e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63011.1 - 3.1e-09 36.6 0.1 3.2e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1977 PF09320.6 EMD63011.1 - 0.09 13.0 7.1 7.2 6.9 3.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) dNK PF01712.14 EMD63011.1 - 1 9.2 8.4 1.5 8.6 5.1 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase Sds3 PF08598.6 EMD63012.1 - 4.6e-27 94.9 9.0 4.6e-27 94.9 6.3 3.0 2 2 0 2 2 2 1 Sds3-like DUF1487 PF07368.6 EMD63012.1 - 0.04 13.1 0.4 0.23 10.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) FancD2 PF14631.1 EMD63012.1 - 1.2 6.1 4.1 0.62 7.0 0.8 1.9 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease SseC PF04888.7 EMD63013.1 - 0.15 11.3 7.3 0.18 11.0 5.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Pkinase PF00069.20 EMD63015.1 - 4.1e-51 173.6 0.0 6.1e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63015.1 - 1e-32 113.2 0.0 1.5e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD63015.1 - 0.00042 19.3 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD63015.1 - 0.0058 16.3 0.0 0.1 12.3 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EMD63017.1 - 2.3e-13 49.7 6.5 3.5e-13 49.1 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD63017.1 - 7.9e-08 32.3 1.8 1.8e-07 31.1 1.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD63017.1 - 3.7e-07 29.6 3.7 6.1e-07 28.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD63017.1 - 1.9e-06 27.4 3.7 3e-06 26.8 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD63017.1 - 1.6e-05 24.8 5.4 2.6e-05 24.1 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD63017.1 - 4.2e-05 23.1 2.5 6.4e-05 22.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD63017.1 - 0.001 18.8 2.6 0.0026 17.5 1.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMD63017.1 - 0.014 14.9 5.9 0.023 14.2 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMD63017.1 - 0.019 14.8 4.9 0.037 13.9 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EMD63017.1 - 0.1 12.2 5.5 0.19 11.4 3.8 1.4 1 0 0 1 1 1 0 PHD-finger OAD_gamma PF04277.8 EMD63017.1 - 0.53 10.7 1.6 2.3 8.6 0.0 2.6 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RINGv PF12906.2 EMD63017.1 - 0.81 9.7 5.7 1.6 8.8 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Pro_isomerase PF00160.16 EMD63018.1 - 1.9e-48 164.6 2.0 2.1e-48 164.4 1.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRN3 PF05327.6 EMD63019.1 - 2e-165 551.1 0.0 2e-165 551.1 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF4243 PF14027.1 EMD63019.1 - 0.052 12.9 0.3 0.96 8.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4243) Nop14 PF04147.7 EMD63019.1 - 6.9 4.4 35.4 0.076 10.9 16.0 2.2 2 0 0 2 2 2 0 Nop14-like family SAS4 PF15460.1 EMD63020.1 - 8e-35 118.7 2.6 1.2e-34 118.1 1.8 1.3 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF4482 PF14818.1 EMD63020.1 - 2 9.0 7.4 0.16 12.6 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) PX PF00787.19 EMD63021.1 - 4.1e-21 74.8 0.0 5.4e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF2370 PF10176.4 EMD63021.1 - 0.051 12.9 0.1 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FAD_binding_3 PF01494.14 EMD63024.1 - 4.7e-27 94.9 0.1 1.1e-24 87.1 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD63024.1 - 2e-05 23.6 0.0 0.055 12.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD63024.1 - 0.0012 18.7 0.0 0.0057 16.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMD63024.1 - 0.0057 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EMD63024.1 - 0.0063 15.4 1.4 0.11 11.3 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMD63024.1 - 0.039 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMD63024.1 - 0.094 13.1 0.0 4.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD63024.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD63024.1 - 0.11 10.9 0.0 1.2 7.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 EMD63024.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ChaC PF04752.7 EMD63025.1 - 1.1e-48 165.5 0.0 1.6e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein Zip PF02535.17 EMD63026.1 - 2.4e-48 164.7 6.4 3.5e-48 164.2 4.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF566 PF04484.7 EMD63027.1 - 2.4 7.6 6.4 4.2 6.7 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) VRR_NUC PF08774.6 EMD63028.1 - 4.6e-15 55.4 0.0 1.4e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain ketoacyl-synt PF00109.21 EMD63029.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCH PF00443.24 EMD63030.1 - 2.5e-63 213.7 0.0 2.5e-63 213.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD63030.1 - 4.2e-29 101.9 3.3 1.5e-23 83.6 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase MYCBPAP PF14646.1 EMD63030.1 - 0.008 14.9 4.2 0.016 13.9 2.9 1.5 1 0 0 1 1 1 1 MYCBP-associated protein family Trp_dioxygenase PF03301.8 EMD63030.1 - 0.37 9.8 4.3 0.38 9.8 1.7 1.8 2 0 0 2 2 2 0 Tryptophan 2,3-dioxygenase HrpA_pilin PF09589.5 EMD63030.1 - 2.1 8.8 7.3 2.6 8.5 2.7 2.3 2 1 0 2 2 2 0 HrpA pilus formation protein Nop25 PF09805.4 EMD63030.1 - 2.1 8.4 19.6 0.065 13.3 7.2 2.7 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) Peptidase_C98 PF15499.1 EMD63030.1 - 4.5 6.4 13.1 0.078 12.2 2.0 2.6 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Amino_oxidase PF01593.19 EMD63031.1 - 2.6e-92 310.2 0.1 1.7e-91 307.5 0.1 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EMD63031.1 - 6.9e-10 38.9 0.1 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EMD63031.1 - 1.3e-07 31.5 0.1 3.6e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD63031.1 - 0.0024 17.9 0.5 0.25 11.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD63031.1 - 0.0037 16.2 1.8 0.15 10.9 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD63031.1 - 0.0086 15.8 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HMG_box PF00505.14 EMD63031.1 - 0.011 15.9 3.6 0.015 15.5 0.6 2.4 1 1 1 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD63031.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain K_oxygenase PF13434.1 EMD63031.1 - 0.087 11.7 0.1 7.1 5.4 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SNase PF00565.12 EMD63032.1 - 3e-25 88.5 0.5 4.9e-25 87.8 0.4 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CPSase_L_D2 PF02786.12 EMD63033.1 - 4.3e-107 356.1 0.0 3.8e-81 271.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EMD63033.1 - 1.6e-42 144.1 0.0 3.4e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMD63033.1 - 4.5e-36 124.3 0.0 5.3e-20 71.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EMD63033.1 - 1.3e-34 118.5 0.0 1.5e-16 60.4 0.0 3.3 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EMD63033.1 - 1.2e-22 80.1 0.0 9.6e-08 31.1 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMD63033.1 - 9.8e-19 67.3 0.0 9.1e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMD63033.1 - 2.6e-16 59.6 0.1 2.8e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EMD63033.1 - 1.2e-09 37.9 0.0 5.6e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EMD63033.1 - 0.00017 20.8 0.1 0.056 12.6 0.1 3.2 2 1 1 3 3 3 1 ATP-grasp domain DUF202 PF02656.10 EMD63035.1 - 1.1e-18 67.2 0.1 1.1e-18 67.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PhaG_MnhG_YufB PF03334.9 EMD63035.1 - 3.6 7.7 10.1 0.21 11.6 3.4 1.7 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Glyco_transf_34 PF05637.7 EMD63037.1 - 5.5e-65 219.2 0.8 8.2e-65 218.6 0.6 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF4562 PF15123.1 EMD63037.1 - 4.3 7.2 8.6 5.7 6.8 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4562) Sugar_tr PF00083.19 EMD63039.1 - 7.1e-21 74.3 21.5 2.2e-18 66.0 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD63039.1 - 1.5e-06 27.1 34.7 5.5e-05 22.0 7.6 3.2 1 1 1 3 3 3 2 Major Facilitator Superfamily PIR PF00399.14 EMD63040.1 - 1.4e-06 27.4 1.3 3.6e-06 26.1 0.9 1.7 1 0 0 1 1 1 1 Yeast PIR protein repeat CBF PF03914.12 EMD63041.1 - 1.7e-48 164.1 0.1 1.9e-47 160.7 0.0 2.6 3 0 0 3 3 3 1 CBF/Mak21 family DUF4220 PF13968.1 EMD63041.1 - 0.049 12.7 0.2 0.11 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Mt_ATP-synt_B PF05405.9 EMD63042.1 - 1.1e-48 164.7 9.2 1.4e-48 164.4 6.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DivIC PF04977.10 EMD63042.1 - 1.4 8.4 8.5 0.13 11.7 0.9 2.5 2 1 0 2 2 2 0 Septum formation initiator Epimerase PF01370.16 EMD63043.1 - 3.2e-21 75.8 0.0 4.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD63043.1 - 4.5e-12 45.4 0.0 6.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMD63043.1 - 0.00016 20.4 0.0 0.00036 19.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD63043.1 - 0.00027 20.8 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMD63043.1 - 0.00054 18.9 0.0 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMD63043.1 - 0.0035 17.3 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD63043.1 - 0.079 11.8 0.0 0.18 10.6 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 EMD63043.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Topoisom_I_N PF02919.10 EMD63044.1 - 1.6e-98 328.2 4.4 1.6e-98 328.2 3.1 3.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMD63044.1 - 8.4e-85 283.6 4.3 8.4e-85 283.6 3.0 2.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMD63044.1 - 8.2e-33 111.8 0.4 8.2e-33 111.8 0.2 2.0 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EMD63044.1 - 0.04 13.0 0.0 0.099 11.7 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 EMD63045.1 - 4.9e-71 239.4 3.6 5.6e-71 239.2 2.5 1.0 1 0 0 1 1 1 1 ATP synthase Thg1C PF14413.1 EMD63045.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Thg1 C terminal domain Rotamase_3 PF13616.1 EMD63045.1 - 0.065 13.4 0.1 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain RNA_pol_A_bac PF01000.21 EMD63047.1 - 7.4e-25 87.2 0.0 1.2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMD63047.1 - 7.9e-15 53.7 0.0 1.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EMD63048.1 - 3.5e-133 442.7 0.0 4.9e-133 442.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4404 PF14357.1 EMD63048.1 - 0.17 12.2 0.5 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TFIIS_M PF07500.9 EMD63049.1 - 3.8e-30 104.3 2.6 3.8e-30 104.3 1.8 2.1 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EMD63049.1 - 2.6e-18 65.3 8.7 4.2e-18 64.6 6.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EMD63049.1 - 1.4e-15 56.5 1.0 1.4e-15 56.5 0.7 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EMD63049.1 - 0.17 11.5 5.6 0.54 9.9 3.8 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CAP_N PF01213.14 EMD63049.1 - 0.95 8.6 8.8 2.7 7.2 6.1 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NuA4 PF09340.5 EMD63050.1 - 4.4e-26 90.3 0.1 4.4e-26 90.3 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AKAP7_RIRII_bdg PF10470.4 EMD63050.1 - 7.4 6.4 11.0 0.42 10.4 0.2 3.0 2 1 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein zf-H2C2_2 PF13465.1 EMD63052.1 - 9e-11 41.5 12.3 1.3e-05 25.2 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMD63052.1 - 1.8e-10 40.5 11.3 1.1e-05 25.5 3.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD63052.1 - 1.9e-07 30.9 8.8 0.00011 22.2 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMD63052.1 - 7.1e-06 26.0 1.3 2.1e-05 24.5 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD63052.1 - 6.7e-05 22.9 5.2 0.00011 22.2 1.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMD63052.1 - 0.0019 18.0 7.0 0.0077 16.1 1.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMD63052.1 - 0.071 13.2 2.4 0.078 13.0 0.9 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EMD63052.1 - 0.47 10.1 4.0 7.9 6.2 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EMD63052.1 - 1.6 8.5 6.5 13 5.5 4.5 2.2 1 1 0 1 1 1 0 BED zinc finger HATPase_c PF02518.21 EMD63054.1 - 4.1e-30 103.7 0.2 7.7e-30 102.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EMD63054.1 - 1.3e-20 73.7 0.1 1.2e-11 44.8 0.0 4.6 4 0 0 4 4 4 3 PAS domain HisKA PF00512.20 EMD63054.1 - 1.3e-20 73.1 1.1 2.3e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EMD63054.1 - 8.7e-20 70.8 0.1 3.5e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 EMD63054.1 - 7.1e-15 54.8 0.9 2.3e-14 53.2 0.6 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EMD63054.1 - 1.2e-14 54.2 0.8 2.2e-05 24.4 0.0 4.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 EMD63054.1 - 3.4e-13 49.3 0.0 3.2e-05 23.6 0.0 3.8 3 0 0 3 3 3 3 PAS fold HATPase_c_3 PF13589.1 EMD63054.1 - 0.0023 17.6 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.1 EMD63054.1 - 0.014 15.2 0.0 0.9 9.5 0.0 3.3 3 0 0 3 3 3 0 PAS domain Yos1 PF08571.5 EMD63055.1 - 8.6e-31 105.8 0.4 9.6e-31 105.7 0.3 1.0 1 0 0 1 1 1 1 Yos1-like TFIIF_beta PF02270.10 EMD63057.1 - 5.6e-48 164.1 0.1 6.9e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit PCI PF01399.22 EMD63058.1 - 3.6e-13 49.7 0.0 1.1e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EMD63058.1 - 4.3e-05 22.9 0.2 8.9e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EMD63058.1 - 0.0012 19.0 4.7 1.8 8.9 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 EMD63058.1 - 0.018 14.1 0.8 0.033 13.3 0.6 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 EMD63058.1 - 0.043 13.9 0.1 0.71 10.0 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_S8e PF01201.17 EMD63060.1 - 9.7e-36 122.8 8.4 7.2e-35 120.0 5.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 EMD63060.1 - 0.64 9.3 8.4 0.29 10.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) WD40 PF00400.27 EMD63061.1 - 1.6e-06 27.7 1.4 4.8e-05 23.0 0.1 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Chitin_synth_2 PF03142.10 EMD63062.1 - 5.1e-293 972.2 0.5 7.3e-293 971.7 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EMD63062.1 - 6.7e-18 65.0 2.8 2.9e-17 63.0 2.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD63062.1 - 1.2e-15 57.9 0.0 1.1e-13 51.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EMD63062.1 - 1.4e-07 31.1 0.0 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EMD63062.1 - 1.5e-05 24.3 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD63062.1 - 0.0031 17.2 0.0 0.038 13.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCA_ABC_TP_C PF12399.3 EMD63062.1 - 0.027 14.1 0.4 3.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter Sel1 PF08238.7 EMD63063.1 - 1.2e-36 124.2 28.9 3.5e-06 27.4 1.6 7.6 7 0 0 7 7 7 7 Sel1 repeat Bac_luciferase PF00296.15 EMD63063.1 - 0.0042 16.2 0.9 0.0084 15.2 0.0 1.8 2 0 0 2 2 2 1 Luciferase-like monooxygenase Senescence_reg PF04520.8 EMD63063.1 - 2.1 8.8 10.9 0.75 10.2 0.1 2.9 2 1 1 3 3 3 0 Senescence regulator Aminotran_1_2 PF00155.16 EMD63064.1 - 2.7e-21 75.9 0.0 3.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMD63064.1 - 6.4e-06 24.9 0.0 1.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EMD63064.1 - 0.00027 20.1 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD63064.1 - 0.031 13.3 0.1 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DAD PF02109.11 EMD63065.1 - 1.2e-47 160.6 3.0 1.4e-47 160.3 2.1 1.0 1 0 0 1 1 1 1 DAD family DUF2062 PF09835.4 EMD63065.1 - 0.045 13.3 0.3 0.058 13.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4389 PF14333.1 EMD63065.1 - 0.066 12.9 0.7 0.12 12.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Tmemb_14 PF03647.8 EMD63066.1 - 1.8e-22 79.5 8.6 2.3e-22 79.2 6.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EMD63066.1 - 0.021 15.0 1.4 0.034 14.3 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) GBP_PSP PF02425.10 EMD63066.1 - 0.81 9.2 6.6 1.3 8.6 1.7 2.2 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Bac_luciferase PF00296.15 EMD63068.1 - 6.3e-64 216.0 0.1 8.8e-64 215.5 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Grp1_Fun34_YaaH PF01184.14 EMD63069.1 - 2.8e-27 95.4 11.4 3.2e-27 95.2 7.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Acyl-CoA_dh_2 PF08028.6 EMD63070.1 - 8.1e-15 55.2 1.4 8.1e-15 55.2 1.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD63070.1 - 2.6e-05 24.7 0.1 4.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EMD63070.1 - 0.00055 20.0 1.3 0.0016 18.5 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 EMD63070.1 - 0.054 13.2 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) tRNA-synt_2 PF00152.15 EMD63071.1 - 3.4e-75 252.8 0.0 5.5e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EMD63071.1 - 2.6e-16 59.3 0.0 3.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EMD63071.1 - 6.5e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LTXXQ PF07813.7 EMD63071.1 - 0.003 17.9 4.2 0.01 16.2 2.9 1.9 1 0 0 1 1 1 1 LTXXQ motif family protein tRNA-synt_2d PF01409.15 EMD63071.1 - 0.0038 16.4 0.4 0.78 8.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TMEM247 PF15444.1 EMD63071.1 - 0.55 10.0 3.8 1 9.1 2.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Hid1 PF12722.2 EMD63071.1 - 1.6 6.3 7.1 2.3 5.8 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein p450 PF00067.17 EMD63072.1 - 3.2e-98 329.2 0.0 3.7e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M1 PF01433.15 EMD63073.1 - 8.6e-07 28.3 0.0 0.0065 15.5 0.0 3.3 2 1 0 2 2 2 2 Peptidase family M1 PHD PF00628.24 EMD63074.1 - 0.00089 18.8 1.4 0.00089 18.8 1.0 1.7 2 0 0 2 2 2 1 PHD-finger zf-CSL PF05207.8 EMD63074.1 - 0.04 13.4 0.4 0.26 10.8 0.1 2.2 2 0 0 2 2 2 0 CSL zinc finger Prok-RING_1 PF14446.1 EMD63074.1 - 0.065 12.9 4.1 0.57 9.9 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AT_hook PF02178.14 EMD63074.1 - 1.1 9.1 10.0 5.2 7.0 0.4 3.1 2 0 0 2 2 2 0 AT hook motif PH PF00169.24 EMD63075.1 - 0.0012 18.9 0.0 0.0067 16.6 0.0 2.3 2 0 0 2 2 2 1 PH domain EthD PF07110.6 EMD63076.1 - 0.0038 18.1 1.5 0.18 12.7 1.1 2.1 1 1 0 1 1 1 1 EthD domain WSC PF01822.14 EMD63077.1 - 1.1e-09 38.0 2.0 1.1e-09 38.0 1.4 2.3 1 1 2 3 3 3 1 WSC domain OPT PF03169.10 EMD63078.1 - 2.7e-176 587.6 53.7 3.1e-176 587.5 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4638 PF15472.1 EMD63078.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Glyco_hydro_62 PF03664.8 EMD63079.1 - 1.4e-66 224.3 2.2 1.7e-66 224.1 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Sel1 PF08238.7 EMD63080.1 - 7.7e-17 61.3 16.6 2.6e-06 27.8 0.4 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 EMD63080.1 - 0.26 12.0 4.5 1.1 9.9 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1776 PF08643.5 EMD63081.1 - 4.3e-92 308.4 0.0 5.3e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 EMD63081.1 - 0.022 14.6 0.0 0.15 11.9 0.0 2.5 3 1 0 3 3 3 0 short chain dehydrogenase WLM PF08325.5 EMD63082.1 - 8e-47 159.5 0.2 1.2e-46 158.9 0.2 1.3 1 0 0 1 1 1 1 WLM domain DZR PF12773.2 EMD63082.1 - 0.00036 20.2 4.6 0.0036 17.1 3.2 2.2 1 1 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.13 EMD63082.1 - 0.0023 16.9 0.6 0.0023 16.9 0.4 3.1 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others SprT-like PF10263.4 EMD63082.1 - 0.0062 16.2 1.1 0.017 14.8 0.0 2.2 3 0 0 3 3 3 1 SprT-like family DUF45 PF01863.12 EMD63082.1 - 0.029 14.1 0.7 0.064 13.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-Sec23_Sec24 PF04810.10 EMD63082.1 - 0.35 10.4 8.7 2.3 7.8 0.1 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Scm3 PF10384.4 EMD63084.1 - 1.7e-20 72.2 0.7 3.4e-20 71.2 0.5 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 zf-C2H2 PF00096.21 EMD63084.1 - 0.0016 18.6 0.2 0.0039 17.4 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMD63084.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD63084.1 - 0.0054 16.8 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMD63084.1 - 0.013 15.7 0.9 0.036 14.3 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMD63084.1 - 0.065 12.9 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type APG6 PF04111.7 EMD63085.1 - 2.5e-117 391.4 0.0 3e-117 391.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 mRNA_stabil PF13929.1 EMD63085.1 - 0.0061 15.5 0.5 0.009 15.0 0.4 1.2 1 0 0 1 1 1 1 mRNA stabilisation DUF2968 PF11180.3 EMD63085.1 - 0.012 15.0 9.1 0.022 14.1 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4472 PF14739.1 EMD63085.1 - 0.023 15.1 3.2 0.064 13.7 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) HOOK PF05622.7 EMD63085.1 - 0.027 12.2 3.8 0.039 11.7 2.6 1.1 1 0 0 1 1 1 0 HOOK protein Jnk-SapK_ap_N PF09744.4 EMD63085.1 - 0.051 13.5 3.6 0.095 12.6 2.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.4 EMD63085.1 - 0.11 12.3 5.9 0.19 11.5 4.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2972 PF11186.3 EMD63085.1 - 0.12 12.2 0.5 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) HAUS-augmin3 PF14932.1 EMD63085.1 - 0.17 11.0 6.5 0.28 10.3 4.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.9 EMD63085.1 - 0.42 10.5 9.1 0.78 9.6 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 EMD63085.1 - 0.77 9.4 6.0 1.3 8.6 4.2 1.3 1 0 0 1 1 1 0 Mnd1 family FUSC PF04632.7 EMD63085.1 - 6.2 5.1 5.8 11 4.2 4.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family LRR_6 PF13516.1 EMD63086.1 - 0.03 14.3 0.6 23 5.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.2 EMD63086.1 - 0.048 13.4 0.0 0.48 10.1 0.0 2.8 2 1 0 2 2 2 0 F-box-like LRR_8 PF13855.1 EMD63086.1 - 0.23 11.2 2.8 8.9 6.1 0.0 3.7 3 1 1 4 4 4 0 Leucine rich repeat FMN_red PF03358.10 EMD63087.1 - 2.1e-12 46.7 0.0 3.5e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMD63087.1 - 1.6e-09 37.8 0.0 3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EMD63087.1 - 2.3e-07 30.5 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EMD63087.1 - 0.0041 17.1 0.0 0.046 13.7 0.0 2.0 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EMD63087.1 - 0.14 11.5 0.1 0.65 9.3 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin Phosphodiest PF01663.17 EMD63088.1 - 1.9e-88 297.2 1.7 2.5e-88 296.8 1.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD63088.1 - 0.0003 20.0 0.0 0.04 13.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.7 EMD63088.1 - 0.0046 16.6 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 2 PglZ domain eIF-3_zeta PF05091.7 EMD63090.1 - 3.4e-200 666.0 0.0 4.1e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EMD63090.1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF569) VMA21 PF09446.5 EMD63091.1 - 4.7e-17 61.6 9.6 6.2e-17 61.2 6.7 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 EMD63092.1 - 8.6e-43 146.2 1.4 1.5e-20 73.2 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD63092.1 - 1.4e-13 50.4 0.2 1.4e-12 47.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD63092.1 - 0.016 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase SH3BGR PF04908.10 EMD63093.1 - 0.0027 17.6 0.0 0.0027 17.6 0.0 3.2 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein bZIP_1 PF00170.16 EMD63094.1 - 0.0057 16.5 10.1 0.017 15.0 7.0 1.7 1 1 0 1 1 1 1 bZIP transcription factor DUF2046 PF09755.4 EMD63094.1 - 0.023 13.6 1.2 0.035 12.9 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) PAP1 PF08601.5 EMD63094.1 - 0.028 14.1 0.4 3.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 DUF904 PF06005.7 EMD63094.1 - 0.21 11.8 2.0 0.24 11.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EMD63094.1 - 0.39 10.5 9.1 0.084 12.7 3.6 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Aldo_ket_red PF00248.16 EMD63095.1 - 2.2e-69 233.4 0.0 2.5e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3693 PF12472.3 EMD63095.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage related protein Pkinase PF00069.20 EMD63097.1 - 0.0068 15.5 0.2 0.022 13.9 0.0 1.8 1 1 0 2 2 2 1 Protein kinase domain p450 PF00067.17 EMD63098.1 - 6.9e-60 202.8 0.0 8.5e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMD63099.1 - 6.2e-34 117.2 40.9 6.2e-34 117.2 28.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SF3b1 PF08920.5 EMD63101.1 - 8.7e-28 97.1 1.1 2.5e-27 95.7 0.8 1.7 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EMD63101.1 - 3.5e-18 65.6 6.4 0.0031 17.7 0.0 7.8 6 3 1 8 8 8 4 HEAT repeats HEAT PF02985.17 EMD63101.1 - 3.6e-14 51.5 8.1 0.0029 17.5 0.1 10.0 11 0 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.1 EMD63101.1 - 8.3e-12 45.2 7.9 0.027 14.9 0.0 7.2 5 2 2 7 7 7 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMD63101.1 - 2.6e-07 30.9 3.7 0.16 12.3 0.0 6.2 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EMD63101.1 - 3.7e-07 28.8 2.1 0.14 10.4 0.2 3.5 1 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 EMD63101.1 - 0.00082 18.7 0.0 0.74 9.1 0.0 4.0 4 0 0 4 4 4 1 CLASP N terminal CRM1_C PF08767.6 EMD63101.1 - 0.0054 15.6 0.8 0.012 14.5 0.1 2.0 2 0 0 2 2 2 1 CRM1 C terminal DUF1546 PF07571.8 EMD63101.1 - 0.017 15.2 0.8 1.2 9.2 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1546) NUC173 PF08161.7 EMD63101.1 - 0.032 13.5 0.7 31 3.8 0.0 4.4 5 0 0 5 5 5 0 NUC173 domain Cnd1 PF12717.2 EMD63101.1 - 0.1 12.4 5.4 5.7 6.7 0.2 4.3 3 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 GFA PF04828.9 EMD63102.1 - 2.9e-08 33.5 0.6 2.9e-08 33.5 0.4 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EMD63102.1 - 0.52 9.8 4.1 0.27 10.7 0.3 2.0 2 0 0 2 2 2 0 CSL zinc finger AKAP2_C PF15304.1 EMD63103.1 - 0.001 18.7 0.7 0.0019 17.9 0.5 1.4 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus DUF4407 PF14362.1 EMD63103.1 - 0.0038 16.2 0.8 0.0058 15.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2365 PF10157.4 EMD63103.1 - 0.049 13.5 0.4 3.8 7.4 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 EMD63103.1 - 0.089 12.6 2.6 1.2 9.0 0.3 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EMD63103.1 - 0.096 11.1 2.7 0.12 10.7 1.8 1.1 1 0 0 1 1 1 0 AAA domain COG6 PF06419.6 EMD63103.1 - 0.12 10.4 4.8 0.18 9.9 3.4 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF1664 PF07889.7 EMD63103.1 - 0.12 12.1 1.6 0.23 11.2 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EMD63103.1 - 0.14 12.4 2.9 3.6 7.9 0.5 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3721 PF12518.3 EMD63103.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function TMF_TATA_bd PF12325.3 EMD63103.1 - 0.44 10.2 5.3 0.23 11.1 1.9 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 EMD63103.1 - 0.9 8.1 6.1 1.4 7.4 4.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EMD63103.1 - 1.1 8.1 6.1 0.51 9.2 1.4 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cgr1 PF03879.9 EMD63104.1 - 4e-36 123.5 34.0 4.6e-36 123.2 23.6 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EMD63104.1 - 1.1 9.5 12.5 1.4 9.2 8.7 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal APG6 PF04111.7 EMD63104.1 - 1.7 7.6 10.2 1.8 7.5 7.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-K PF11802.3 EMD63104.1 - 3.4 6.8 11.8 4.4 6.4 8.2 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TMPIT PF07851.8 EMD63104.1 - 3.5 6.5 7.8 4.2 6.3 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein GAGA_bind PF06217.7 EMD63104.1 - 8.9 6.1 14.2 9.7 6.0 9.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Mito_carr PF00153.22 EMD63105.1 - 5.6e-62 205.4 0.8 7.5e-21 73.6 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EMD63105.1 - 2.1e-24 86.0 6.4 3.1e-23 82.2 0.1 3.3 3 1 0 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family Reo_sigma1 PF01664.11 EMD63108.1 - 0.013 14.6 0.4 0.022 13.8 0.3 1.3 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 Wzy_C PF04932.10 EMD63108.1 - 3.9 7.2 12.3 0.27 10.9 2.1 2.5 1 1 1 2 2 2 0 O-Antigen ligase Vps8 PF12816.2 EMD63111.1 - 1.6e-68 229.8 0.3 3e-68 228.9 0.2 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EMD63111.1 - 9.4e-08 31.7 2.0 0.048 13.2 0.9 3.6 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMD63111.1 - 0.068 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Ring finger domain DUF3752 PF12572.3 EMD63112.1 - 9.6e-44 149.1 13.3 9.6e-44 149.1 9.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DUF4336 PF14234.1 EMD63113.1 - 0.033 13.3 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) FAD_binding_4 PF01565.18 EMD63114.1 - 1.4e-19 69.9 0.6 2.4e-19 69.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD63114.1 - 1.5e-07 31.1 0.0 4.1e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like SMC_N PF02463.14 EMD63115.1 - 5.3e-58 195.8 27.5 4.6e-57 192.7 19.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMD63115.1 - 1.2e-22 80.1 1.6 3.6e-22 78.5 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMD63115.1 - 6.6e-13 49.2 1.9 8.9e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMD63115.1 - 1.1e-08 35.7 20.4 1.1e-08 35.7 14.1 7.0 2 2 1 3 3 3 1 AAA domain MscS_porin PF12795.2 EMD63115.1 - 0.00016 21.0 30.9 0.00016 21.0 21.4 5.5 2 2 2 5 5 5 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EMD63115.1 - 0.00071 19.0 0.1 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 EMD63115.1 - 0.0017 18.1 13.4 0.0017 18.1 9.3 11.0 7 2 7 14 14 14 1 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.22 EMD63115.1 - 0.038 14.2 0.0 0.038 14.2 0.0 6.2 3 2 1 4 4 4 0 ABC transporter FpoO PF10621.4 EMD63115.1 - 1.5 8.8 5.5 12 5.9 0.1 3.5 3 0 0 3 3 3 0 F420H2 dehydrogenase subunit FpoO Reo_sigmaC PF04582.7 EMD63115.1 - 2.4 7.2 38.1 0.067 12.3 0.7 6.5 3 2 3 7 7 7 0 Reovirus sigma C capsid protein HD_3 PF13023.1 EMD63117.1 - 2.4e-45 154.2 0.1 3.3e-45 153.7 0.1 1.2 1 0 0 1 1 1 1 HD domain HAUS6_N PF14661.1 EMD63118.1 - 1.9e-49 168.2 2.0 1.9e-49 168.2 1.4 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF2405 PF10293.4 EMD63118.1 - 0.019 14.7 0.6 0.046 13.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Glyco_transf_90 PF05686.7 EMD63119.1 - 1.6e-15 56.7 0.6 1.6e-11 43.5 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3917 PF13055.1 EMD63119.1 - 0.017 15.3 0.5 0.059 13.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) VPEP PF07589.6 EMD63119.1 - 6.3 6.8 7.7 1.2 9.1 0.8 3.0 3 0 0 3 3 3 0 PEP-CTERM motif MFS_1 PF07690.11 EMD63120.1 - 4.4e-19 68.4 27.6 4.4e-19 68.4 19.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63120.1 - 0.00033 19.3 8.5 0.00033 19.3 5.9 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter NAD_binding_2 PF03446.10 EMD63121.1 - 9.5e-31 106.8 0.1 1.5e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMD63121.1 - 5.2e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMD63121.1 - 2.1e-08 34.3 0.0 3.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EMD63121.1 - 6.2e-08 32.7 0.1 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.17 EMD63121.1 - 0.00034 21.1 0.0 0.00074 20.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 EMD63121.1 - 0.00048 19.5 0.5 0.0028 17.0 0.0 2.3 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EMD63121.1 - 0.00054 19.3 1.2 0.0025 17.1 0.8 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OCD_Mu_crystall PF02423.10 EMD63121.1 - 0.00074 18.3 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.19 EMD63121.1 - 0.00088 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMD63121.1 - 0.0029 17.5 0.9 0.0084 16.0 0.3 2.0 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_10 PF13460.1 EMD63121.1 - 0.0051 16.8 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD63121.1 - 0.0058 15.6 0.1 0.0087 15.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EMD63121.1 - 0.0099 15.8 0.4 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD63121.1 - 0.011 15.3 0.2 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 KR domain PDH PF02153.12 EMD63121.1 - 0.02 13.7 0.2 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF619 PF04768.8 EMD63122.1 - 4.2e-55 185.7 0.0 1e-53 181.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF619) DUF1604 PF07713.8 EMD63122.1 - 0.86 9.4 5.0 0.3 10.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) VRR_NUC PF08774.6 EMD63123.1 - 0.048 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 VRR-NUC domain SnoaL_2 PF12680.2 EMD63123.1 - 0.077 13.4 0.1 0.095 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Rif1_N PF12231.3 EMD63123.1 - 0.09 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal dsrm PF00035.20 EMD63124.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.6 1 1 0 1 1 1 0 Double-stranded RNA binding motif DUF3245 PF11595.3 EMD63125.1 - 0.05 13.8 0.2 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Pro_isomerase PF00160.16 EMD63126.1 - 1.4e-47 161.7 0.5 1.6e-47 161.5 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.17 EMD63127.1 - 6.2e-62 209.6 0.0 8.6e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EMD63128.1 - 6.9e-14 51.6 2.4 1.5e-11 44.0 1.6 3.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD63128.1 - 1.7e-09 37.1 1.4 3.5e-07 29.4 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD63128.1 - 5.2e-08 32.1 0.0 8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD63128.1 - 3.1e-07 30.4 0.1 2e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD63128.1 - 7.5e-07 29.0 0.1 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMD63128.1 - 1.8e-06 26.6 0.2 0.00051 18.6 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 EMD63128.1 - 0.0001 21.2 0.1 0.0031 16.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMD63128.1 - 0.00012 21.3 1.3 0.001 18.2 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD63128.1 - 0.00017 21.7 0.1 0.00099 19.2 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD63128.1 - 0.0018 17.2 0.6 0.026 13.4 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EMD63128.1 - 0.0019 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMD63128.1 - 0.0063 16.8 0.1 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD63128.1 - 0.0084 15.2 0.2 0.5 9.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EMD63128.1 - 0.017 14.7 0.0 0.067 12.7 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMD63128.1 - 0.15 11.6 0.2 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GTP_cyclohydroI PF01227.17 EMD63129.1 - 0.0056 15.9 0.1 0.0092 15.2 0.1 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase I NmrA PF05368.8 EMD63131.1 - 3.7e-27 95.0 0.0 5.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD63131.1 - 2.3e-11 44.0 0.0 3.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD63131.1 - 2.5e-06 27.0 0.0 4.9e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD63131.1 - 0.0041 17.0 0.1 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD63131.1 - 0.01 15.5 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EMD63131.1 - 0.028 13.3 0.1 0.49 9.2 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 EMD63131.1 - 0.071 11.8 0.1 0.24 10.0 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMD63131.1 - 0.11 12.7 0.1 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PALP PF00291.20 EMD63132.1 - 5.5e-57 193.3 0.2 7e-57 192.9 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EMD63132.1 - 3.7e-10 39.4 0.0 3.2e-07 30.0 0.0 2.9 2 0 0 2 2 2 2 CBS domain SRPRB PF09439.5 EMD63133.1 - 5.5e-30 103.9 0.0 2.4e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EMD63133.1 - 6.6e-05 22.2 0.0 0.00016 20.9 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD63133.1 - 6.7e-05 22.1 0.0 0.00024 20.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.24 EMD63133.1 - 0.00025 21.2 0.0 0.00042 20.5 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD63133.1 - 0.00037 20.5 1.6 0.0066 16.4 0.9 2.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 EMD63133.1 - 0.00079 19.0 0.0 0.087 12.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EMD63133.1 - 0.0047 16.3 0.0 0.064 12.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD63133.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EMD63133.1 - 0.032 14.7 0.0 0.21 12.0 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein AAA_19 PF13245.1 EMD63133.1 - 0.036 13.8 0.2 0.098 12.4 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EMD63133.1 - 0.05 12.6 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EMD63133.1 - 0.05 13.4 0.3 0.093 12.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD63133.1 - 0.053 13.0 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EMD63133.1 - 0.056 13.1 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Sec23_helical PF04815.10 EMD63133.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Sigma54_activat PF00158.21 EMD63133.1 - 0.095 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EMD63133.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMD63133.1 - 0.11 13.2 0.1 0.29 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain NDT80_PhoG PF05224.7 EMD63135.1 - 3.2e-38 131.5 0.2 4.8e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family NOT2_3_5 PF04153.13 EMD63136.1 - 2.3e-28 98.7 0.4 2.3e-28 98.7 0.3 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Fungal_trans PF04082.13 EMD63137.1 - 2.1e-31 108.7 0.0 5.1e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63137.1 - 3.8e-09 36.3 8.2 6e-09 35.6 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 EMD63138.1 - 1.6e-19 69.9 0.6 2.1e-19 69.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMD63138.1 - 0.0069 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain LysM PF01476.15 EMD63140.1 - 0.018 14.8 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 0 LysM domain Ribosomal_L40e PF01020.12 EMD63140.1 - 0.086 12.4 0.3 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L40e family Peptidase_M1 PF01433.15 EMD63141.1 - 4.5e-73 246.5 0.0 6.2e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMD63141.1 - 5.1e-43 146.0 0.1 8.1e-43 145.4 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMD63141.1 - 4.8e-14 52.4 0.7 8.3e-14 51.7 0.5 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EMD63141.1 - 0.077 12.9 3.9 0.31 11.0 1.3 2.7 2 1 0 2 2 2 0 M61 glycyl aminopeptidase LacAB_rpiB PF02502.13 EMD63142.1 - 1.9e-42 144.2 0.1 2.7e-42 143.7 0.1 1.2 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Rhodanese PF00581.15 EMD63143.1 - 7.3e-12 45.6 0.1 3.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Thioredoxin PF00085.15 EMD63144.1 - 1.6e-45 153.0 2.9 1e-25 89.3 0.0 4.4 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EMD63144.1 - 3.4e-13 49.8 0.0 3.5e-05 23.7 0.0 4.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMD63144.1 - 4.7e-09 36.2 0.6 0.00027 20.9 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD63144.1 - 4.3e-07 30.1 8.3 0.0046 17.1 0.1 4.3 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMD63144.1 - 5.7e-05 23.0 0.1 0.0013 18.7 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EMD63144.1 - 0.00061 19.6 0.0 0.91 9.4 0.0 3.4 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EMD63144.1 - 0.049 13.4 0.0 0.7 9.7 0.0 3.0 5 0 0 5 5 5 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EMD63144.1 - 0.067 12.7 1.9 2 7.9 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin NPHI_C PF08469.5 EMD63144.1 - 0.11 12.3 0.5 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal ETC_C1_NDUFA5 PF04716.9 EMD63145.1 - 1.5e-23 82.0 0.1 2.9e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Fungal_trans PF04082.13 EMD63150.1 - 1.1e-18 67.0 0.1 2.8e-18 65.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMD63150.1 - 3.6e-09 36.4 11.5 3.8e-06 26.8 3.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD63150.1 - 1.6e-05 24.9 17.4 0.0026 17.9 4.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD63150.1 - 0.0049 17.1 20.5 0.047 14.0 5.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Suf PF05843.9 EMD63150.1 - 0.0053 16.5 9.2 0.011 15.4 6.4 1.5 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) zf-Di19 PF05605.7 EMD63150.1 - 0.025 14.6 4.2 0.055 13.6 2.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4175 PF13779.1 EMD63150.1 - 0.099 10.3 21.1 0.22 9.1 14.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zn_Tnp_IS1595 PF12760.2 EMD63150.1 - 0.13 12.0 4.0 0.35 10.7 2.8 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.1 EMD63150.1 - 1.2 8.8 6.7 2.9 7.6 1.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EMD63150.1 - 4.2 7.2 15.1 2.4 7.9 4.1 2.7 1 1 1 2 2 2 0 BED zinc finger SH3_1 PF00018.23 EMD63155.1 - 7.4e-24 82.8 0.0 1.4e-11 43.5 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EMD63155.1 - 7.1e-18 63.9 0.1 6.7e-09 35.1 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMD63155.1 - 1.7e-13 49.8 0.0 5.2e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EMD63155.1 - 3.9e-11 42.7 0.0 9.1e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EMD63155.1 - 7.5e-05 22.3 0.2 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.11 EMD63157.1 - 4.8e-66 222.1 1.4 6.4e-66 221.8 1.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMD63157.1 - 0.00014 21.6 0.3 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EMD63157.1 - 0.09 13.0 0.3 0.4 11.0 0.1 2.2 2 1 0 2 2 2 0 PCI domain EAP30 PF04157.11 EMD63158.1 - 1.3e-57 194.5 0.1 1.7e-57 194.1 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EMD63158.1 - 2.1e-25 88.3 0.0 3.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EMD63158.1 - 0.00062 19.2 0.5 0.00062 19.2 0.3 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EMD63158.1 - 0.0021 17.1 2.1 0.0021 17.1 1.5 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EMD63158.1 - 0.027 14.2 0.8 0.027 14.2 0.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EMD63158.1 - 0.084 12.5 1.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain GCC2_GCC3 PF07699.8 EMD63158.1 - 0.68 9.5 6.3 0.1 12.1 1.1 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 F-box-like_2 PF13013.1 EMD63159.1 - 0.0025 17.5 0.0 0.0068 16.1 0.0 1.7 1 1 0 1 1 1 1 F-box-like domain Trypsin PF00089.21 EMD63161.1 - 4.8e-63 212.6 6.5 5.5e-63 212.4 4.5 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMD63161.1 - 1.4e-05 25.0 2.1 7.9e-05 22.6 1.4 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF2418 PF10332.4 EMD63162.1 - 9e-33 112.5 0.1 1.5e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EMD63163.1 - 4e-31 107.2 0.0 4.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EMD63164.1 - 2.7e-26 92.3 0.1 3.4e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 ML domain MFS_1 PF07690.11 EMD63165.1 - 1.8e-29 102.5 29.9 2.5e-29 102.1 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S8 PF00082.17 EMD63166.1 - 6.5e-22 77.9 1.0 8.4e-22 77.6 0.7 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD63166.1 - 0.0093 16.5 0.0 0.027 15.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 WSC PF01822.14 EMD63167.1 - 7e-11 41.9 10.1 7.8e-11 41.7 7.0 1.0 1 0 0 1 1 1 1 WSC domain zf-CSL PF05207.8 EMD63167.1 - 0.026 14.0 0.5 0.026 14.0 0.3 1.6 1 1 1 2 2 2 0 CSL zinc finger Sugar_tr PF00083.19 EMD63168.1 - 6.6e-82 275.4 26.5 7.7e-82 275.2 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD63168.1 - 3.5e-14 52.3 34.5 3.5e-14 52.3 23.9 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EMD63169.1 - 7.6e-22 77.4 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63169.1 - 0.0061 16.4 5.4 0.011 15.6 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.13 EMD63170.1 - 9e-40 136.5 0.0 2.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 Melibiase E1-E2_ATPase PF00122.15 EMD63171.1 - 4.5e-51 173.1 0.1 2e-50 170.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMD63171.1 - 7.8e-39 134.3 0.0 1.3e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMD63171.1 - 1.2e-23 82.9 1.8 1.5e-10 41.0 0.2 3.4 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EMD63171.1 - 5.6e-17 62.5 0.0 1.4e-16 61.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD63171.1 - 0.0008 19.0 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BON PF04972.12 EMD63171.1 - 0.00082 19.0 0.3 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 BON domain RR_TM4-6 PF06459.7 EMD63172.1 - 0.46 10.3 4.4 0.58 9.9 3.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 EMD63172.1 - 2.4 7.9 11.1 2.7 7.7 7.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 EMD63172.1 - 8.6 4.6 10.0 9.5 4.5 6.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Coiled-coil_56 PF09813.4 EMD63173.1 - 5.6e-07 29.4 0.0 6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EMD63174.1 - 4.5e-75 252.1 0.0 7.1e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.1 EMD63174.1 - 0.11 12.8 1.4 3.8 7.8 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats tRNA-synt_1 PF00133.17 EMD63175.1 - 3.5e-216 718.8 0.0 3.5e-215 715.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMD63175.1 - 4.9e-33 114.0 0.2 4.9e-33 114.0 0.2 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMD63175.1 - 1.7e-17 63.1 1.1 1.3e-07 30.6 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMD63175.1 - 2e-10 40.2 6.6 3.4e-09 36.2 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1b PF00579.20 EMD63175.1 - 0.014 14.5 6.5 4.9 6.1 0.0 4.2 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) tRNA-synt_1e PF01406.14 EMD63175.1 - 0.017 14.2 2.1 0.49 9.4 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EMD63175.1 - 0.25 10.1 0.0 0.25 10.1 0.0 3.2 5 0 0 5 5 5 0 tRNA synthetases class I (R) Pkinase PF00069.20 EMD63176.1 - 3.2e-60 203.4 0.1 3.7e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63176.1 - 1.2e-19 70.4 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD63176.1 - 1.4e-07 31.5 0.0 3.3e-05 23.7 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD63176.1 - 0.0066 16.0 0.1 0.018 14.5 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMD63176.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EMD63176.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_P_p30 PF01876.11 EMD63177.1 - 4.6e-48 162.2 0.0 7e-48 161.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF1295 PF06966.7 EMD63179.1 - 4.3e-57 193.1 0.3 5.7e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EMD63179.1 - 1.6e-05 24.7 0.2 1.6e-05 24.7 0.1 3.5 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EMD63179.1 - 3.1e-05 24.0 1.4 4.1e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMD63179.1 - 0.0043 17.1 4.5 0.011 15.7 0.1 3.1 2 1 0 3 3 3 1 Phospholipid methyltransferase DUF3602 PF12223.3 EMD63180.1 - 5.5e-15 55.5 23.8 3.3e-11 43.4 5.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Aldolase_II PF00596.16 EMD63181.1 - 1.3e-43 148.8 0.0 1.5e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain BNR PF02012.15 EMD63182.1 - 1.2e-10 39.5 26.7 0.9 9.6 0.1 10.1 10 0 0 10 10 10 6 BNR/Asp-box repeat BNR_2 PF13088.1 EMD63182.1 - 2.3e-08 33.6 3.4 0.012 14.9 0.0 5.9 4 3 0 4 4 4 2 BNR repeat-like domain Peptidase_S8 PF00082.17 EMD63183.1 - 4.1e-41 140.9 11.6 5.6e-41 140.5 8.0 1.1 1 0 0 1 1 1 1 Subtilase family FAD_binding_2 PF00890.19 EMD63185.1 - 1.3e-128 429.4 3.6 1.6e-128 429.1 2.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMD63185.1 - 1.3e-46 157.6 0.6 1.9e-46 157.1 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMD63185.1 - 7.3e-08 32.5 0.0 0.0021 17.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD63185.1 - 1.1e-05 24.6 0.2 0.016 14.3 0.0 3.0 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EMD63185.1 - 1.1e-05 24.4 2.0 0.0099 14.7 1.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EMD63185.1 - 0.00021 20.2 2.5 0.0052 15.7 1.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMD63185.1 - 0.0056 15.7 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD63185.1 - 0.065 11.6 0.7 0.2 10.1 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EMD63185.1 - 0.12 12.3 2.7 1.1 9.2 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_MA_2 PF13485.1 EMD63186.1 - 4.3e-06 26.8 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 EMD63186.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Mucin PF01456.12 EMD63186.1 - 5.8 6.6 28.5 0.66 9.7 16.1 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 EMD63187.1 - 8.2e-16 57.2 0.0 9.8e-16 56.9 0.0 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Gmad1 PF10647.4 EMD63187.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EMD63187.1 - 0.048 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF3732 PF12532.3 EMD63187.1 - 0.069 12.6 0.0 0.069 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Pkinase PF00069.20 EMD63188.1 - 1.8e-12 46.9 2.7 1.6e-10 40.5 1.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63188.1 - 0.0056 15.7 0.6 0.01 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMD63188.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L3 PF00297.17 EMD63189.1 - 7.3e-117 389.4 6.2 9.1e-117 389.1 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.27 EMD63190.1 - 4.6e-13 48.5 2.0 0.14 12.0 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat PMT PF02366.13 EMD63191.1 - 7.9e-79 264.4 17.9 7.9e-79 264.4 12.4 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UAA PF08449.6 EMD63191.1 - 6.9e-76 255.0 16.4 6.9e-76 255.0 11.4 1.8 2 0 0 2 2 2 1 UAA transporter family MIR PF02815.14 EMD63191.1 - 7.8e-20 71.2 1.3 2.7e-19 69.4 0.4 2.0 1 1 1 2 2 2 2 MIR domain Nuc_sug_transp PF04142.10 EMD63191.1 - 7.1e-08 31.8 0.2 1.7e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EMD63191.1 - 0.00013 21.6 5.8 0.00013 21.6 4.0 3.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family DUF334 PF03904.8 EMD63191.1 - 0.085 12.1 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) TPR_11 PF13414.1 EMD63192.1 - 4.5e-23 80.6 6.9 6.7e-11 41.6 0.3 4.5 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EMD63192.1 - 1.8e-21 74.7 3.2 1.2e-07 31.0 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMD63192.1 - 5.2e-20 69.6 6.2 3.4e-06 26.5 0.1 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63192.1 - 7.8e-16 58.2 7.2 2.2e-06 28.1 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD63192.1 - 4e-15 54.9 13.7 2.4e-05 24.5 0.2 6.1 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD63192.1 - 6.6e-14 50.8 1.3 0.011 15.9 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMD63192.1 - 7.4e-14 51.8 3.4 0.0017 18.6 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMD63192.1 - 1.9e-12 46.9 2.4 4.5e-07 29.7 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMD63192.1 - 2e-08 33.9 1.9 0.0012 18.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD63192.1 - 2.3e-08 33.2 7.3 0.017 14.9 0.0 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMD63192.1 - 2.8e-08 33.7 8.4 0.001 19.1 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD63192.1 - 7.1e-08 31.7 0.1 0.11 12.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD63192.1 - 1.7e-07 31.2 0.5 0.00023 21.2 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMD63192.1 - 3e-06 27.3 2.4 12 6.6 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMD63192.1 - 0.00083 18.4 2.1 0.43 9.5 0.3 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMD63192.1 - 0.011 15.4 0.0 0.78 9.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EMD63192.1 - 0.04 12.6 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1079 PF06435.6 EMD63192.1 - 0.087 12.7 0.3 0.74 9.8 0.1 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) TPR_10 PF13374.1 EMD63192.1 - 0.11 12.4 2.3 2.6 8.1 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 EMD63193.1 - 4.8e-39 131.8 0.2 3.9e-23 80.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63193.1 - 9.8e-30 102.3 0.2 4.6e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63193.1 - 1.9e-19 69.2 0.1 3e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD63193.1 - 0.079 12.8 1.3 0.27 11.0 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif A_deaminase PF00962.17 EMD63194.1 - 2.1e-111 372.0 0.1 2.8e-111 371.6 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Siva PF05458.7 EMD63195.1 - 0.34 10.4 11.9 0.54 9.8 8.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ELMO_CED12 PF04727.8 EMD63196.1 - 6.9e-48 162.4 0.0 1.7e-47 161.1 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EMD63196.1 - 0.0072 16.0 0.0 0.025 14.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) DUF3552 PF12072.3 EMD63196.1 - 0.067 12.3 3.1 0.11 11.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spidroin_MaSp PF11260.3 EMD63196.1 - 0.39 10.8 7.5 0.1 12.6 1.3 2.6 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 Gp49 PF05973.9 EMD63197.1 - 0.083 12.9 0.1 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) Cpn60_TCP1 PF00118.19 EMD63198.1 - 1.3e-126 423.0 14.8 1.6e-126 422.7 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EMD63198.1 - 0.027 13.9 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 EMD63199.1 - 2.4e-40 137.8 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD63199.1 - 4.4e-06 26.8 0.0 0.00061 19.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD63199.1 - 4.5e-05 23.2 0.1 0.00028 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD63199.1 - 0.00024 21.1 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EMD63199.1 - 0.00029 20.8 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMD63199.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMD63199.1 - 0.0036 18.1 0.1 0.012 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD63199.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMD63199.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EMD63199.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMD63199.1 - 0.017 14.7 0.1 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMD63199.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMD63199.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD63199.1 - 0.04 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EMD63199.1 - 0.062 12.4 0.1 4.6 6.2 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 EMD63199.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMD63199.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EMD63199.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EMD63199.1 - 0.1 12.1 0.3 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMD63199.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMD63199.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMD63199.1 - 0.14 11.5 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 EMD63200.1 - 3.7e-37 127.7 0.1 5.4e-37 127.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD63200.1 - 3.2e-12 46.4 0.0 5.5e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMD63200.1 - 2.7 7.5 6.8 18 4.8 3.6 2.4 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Ribonuclease_T2 PF00445.13 EMD63201.1 - 3.3e-28 98.5 0.0 5.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family RNase_T PF00929.19 EMD63203.1 - 1.4e-19 70.9 0.0 3.5e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Exonuclease Bac_luciferase PF00296.15 EMD63205.1 - 2.2e-57 194.5 0.2 2.9e-57 194.1 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 EMD63206.1 - 1.4e-07 31.2 0.0 3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EMD63207.1 - 4.6e-11 42.0 30.1 4.7e-11 42.0 19.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD63207.1 - 3.2e-06 26.7 4.1 3.2e-06 26.7 2.8 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 EMD63208.1 - 2.6e-21 76.6 0.1 4.6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD63208.1 - 6e-16 57.7 0.1 2e-15 56.0 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD63208.1 - 9e-10 38.4 0.0 3.9e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD63208.1 - 5.2e-07 29.7 0.0 2.6e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD63208.1 - 1.1e-05 24.5 0.8 4.8e-05 22.4 0.1 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD63208.1 - 0.00027 20.7 0.0 0.19 11.5 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EMD63208.1 - 0.021 13.7 0.0 5.2 5.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD63208.1 - 0.063 13.6 0.7 5.4 7.5 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EMD63208.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Thi4 PF01946.12 EMD63208.1 - 0.21 10.6 0.0 0.64 9.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family PHO4 PF01384.15 EMD63209.1 - 2.5e-101 338.6 17.4 2.9e-101 338.3 12.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family CFEM PF05730.6 EMD63210.1 - 5.5e-07 29.3 1.1 1.5e-06 27.9 0.8 1.7 1 0 0 1 1 1 1 CFEM domain Ribul_P_3_epim PF00834.14 EMD63211.1 - 6e-64 214.8 0.0 5.4e-63 211.7 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EMD63211.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 EMD63211.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_11 PF08241.7 EMD63212.1 - 3.1e-06 27.5 0.0 8.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD63212.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain LSM PF01423.17 EMD63213.1 - 2.9e-14 52.3 0.1 4.7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EMD63213.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EMD63213.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF59 PF01883.14 EMD63214.1 - 2.9e-06 27.1 0.0 7.5e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 EMD63216.1 - 1.8e-08 33.5 0.1 4e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63216.1 - 5.8e-07 29.3 6.9 1.2e-06 28.2 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2023 PF09633.5 EMD63217.1 - 0.058 13.3 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Xan_ur_permease PF00860.15 EMD63218.1 - 1.4e-38 132.4 25.5 4.3e-37 127.5 17.7 2.7 1 1 0 1 1 1 1 Permease family Zn_clus PF00172.13 EMD63219.1 - 0.00012 21.9 8.8 0.00029 20.6 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.15 EMD63220.1 - 2.8e-14 53.1 0.0 5.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD63220.1 - 0.00021 21.8 0.1 0.0095 16.4 0.0 2.7 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short PF00106.20 EMD63221.1 - 8.3e-08 32.3 0.1 2e-07 31.0 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD63221.1 - 0.0002 21.0 0.0 0.00059 19.5 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMD63221.1 - 0.00044 20.2 0.0 0.0082 16.1 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EMD63221.1 - 0.0046 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 EMD63222.1 - 7.8e-11 41.1 0.0 9.2e-11 40.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 EMD63223.1 - 8.8e-38 128.5 0.1 8.8e-38 128.5 0.0 2.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3176) MFS_1 PF07690.11 EMD63224.1 - 7e-28 97.3 24.5 3.6e-14 52.2 4.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD63224.1 - 6.5e-10 37.9 16.8 2.3e-05 22.9 1.5 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EMD63224.1 - 2.1e-09 36.5 17.5 2.1e-05 23.3 6.0 2.7 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EMD63224.1 - 2.4e-05 22.6 12.5 0.0029 15.8 1.4 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 EMD63224.1 - 0.00014 20.0 8.3 0.023 12.7 0.1 3.6 2 1 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EMD63224.1 - 0.11 12.3 3.9 0.9 9.3 0.1 3.4 3 1 1 4 4 4 0 MFS_1 like family UCR_Fe-S_N PF10399.4 EMD63224.1 - 1.4 8.1 7.0 3.6 6.8 0.1 3.3 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PMM PF03332.8 EMD63226.1 - 0.063 12.8 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase DUF3807 PF12720.2 EMD63227.1 - 4.2e-42 144.2 8.6 6.2e-42 143.6 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF853 PF05872.7 EMD63227.1 - 0.1 10.9 5.9 0.13 10.5 4.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FLO_LFY PF01698.11 EMD63227.1 - 0.52 9.0 8.6 0.66 8.7 6.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3381 PF11861.3 EMD63227.1 - 1.8 8.0 7.0 2.7 7.4 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 EMD63227.1 - 3.2 5.6 11.1 3.9 5.3 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0561 PF10573.4 EMD63227.1 - 10 6.0 10.3 1.2 9.0 2.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 Fasciclin PF02469.17 EMD63228.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain PDGLE PF13190.1 EMD63228.1 - 0.028 14.0 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 PDGLE domain Carb_kinase PF01256.12 EMD63229.1 - 7.3e-57 192.4 0.2 1e-56 191.9 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EMD63229.1 - 0.00052 19.2 0.0 0.00078 18.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EMD63229.1 - 0.039 13.1 0.0 0.074 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PWWP PF00855.12 EMD63230.1 - 1.7e-14 53.7 0.0 1.7e-14 53.7 0.0 3.6 3 0 0 3 3 3 1 PWWP domain CBS PF00571.23 EMD63231.1 - 0.00091 18.9 0.0 0.97 9.2 0.0 3.2 2 1 0 2 2 2 2 CBS domain Spindle_Spc25 PF08234.7 EMD63231.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 PP2C_2 PF13672.1 EMD63232.1 - 1.7e-08 34.1 0.2 2.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EMD63232.1 - 6e-06 25.8 0.0 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EMD63232.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3456 PF11938.3 EMD63232.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Pox_I6 PF04595.8 EMD63232.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family Vps53_N PF04100.7 EMD63233.1 - 1.7e-106 356.2 4.5 3.6e-106 355.1 3.1 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EMD63233.1 - 3e-09 36.2 5.8 6.2e-09 35.1 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EMD63233.1 - 0.0056 16.5 4.4 0.034 14.0 2.7 2.6 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EMD63233.1 - 0.0079 14.4 4.7 0.018 13.2 3.2 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.6 EMD63233.1 - 0.011 14.4 4.8 0.019 13.6 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 EMD63233.1 - 0.036 13.9 5.2 0.049 13.4 2.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEX-2N PF09263.5 EMD63233.1 - 0.062 13.6 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal KxDL PF10241.4 EMD63233.1 - 0.064 13.1 4.6 0.087 12.7 0.2 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein Allexi_40kDa PF05549.6 EMD63233.1 - 0.13 11.5 2.8 0.19 11.0 1.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF342 PF03961.8 EMD63233.1 - 0.28 9.5 1.3 0.5 8.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 EMD63233.1 - 0.59 9.9 4.4 2.1 8.2 3.0 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Flagellin_N PF00669.15 EMD63233.1 - 2.2 8.0 10.6 0.64 9.8 1.9 2.5 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region HEAT_2 PF13646.1 EMD63234.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.6 1 1 0 1 1 1 0 HEAT repeats Nop14 PF04147.7 EMD63235.1 - 6.7e-234 778.5 41.7 7.6e-182 606.3 18.3 2.0 1 1 1 2 2 2 2 Nop14-like family Sulfate_transp PF00916.15 EMD63237.1 - 2e-72 243.5 10.7 3.1e-72 242.9 7.4 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMD63237.1 - 5.8e-31 105.9 2.9 5.8e-31 105.9 2.0 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMD63237.1 - 3.8e-09 35.9 0.0 7.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF457 PF04307.9 EMD63237.1 - 0.26 10.5 6.8 0.062 12.6 1.6 2.3 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) SNN_transmemb PF09049.5 EMD63237.1 - 4.7 6.9 10.6 0.077 12.7 0.2 3.1 3 0 0 3 3 3 0 Stannin transmembrane TAP_C PF03943.8 EMD63238.1 - 1.1e-06 27.9 0.0 2.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.1 EMD63238.1 - 4.2e-05 22.9 0.6 0.00031 20.2 0.1 2.2 2 0 0 2 2 2 1 UBA-like domain LRR_4 PF12799.2 EMD63238.1 - 0.041 13.5 0.2 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF1212 PF06738.7 EMD63238.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) COPIIcoated_ERV PF07970.7 EMD63239.1 - 3.2e-70 236.2 0.2 7.5e-46 156.5 0.1 2.9 3 0 0 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMD63239.1 - 5.2e-36 122.5 0.0 9.8e-35 118.4 0.0 2.3 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3818 PF12825.2 EMD63240.1 - 2.1e-142 473.8 0.8 3.1e-142 473.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMD63240.1 - 5.4e-43 145.9 0.4 5.4e-43 145.9 0.3 1.8 2 0 0 2 2 2 1 PX-associated PX PF00787.19 EMD63240.1 - 5.3e-11 42.3 0.0 2.2e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 PX domain DUF4187 PF13821.1 EMD63241.1 - 1.7e-23 81.9 0.3 4.8e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EMD63241.1 - 5.6e-22 77.8 8.1 5.6e-22 77.8 5.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EMD63241.1 - 2.7e-12 47.3 0.1 7e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 TspO_MBR PF03073.10 EMD63242.1 - 8.4e-41 138.9 9.0 1e-40 138.6 6.2 1.1 1 0 0 1 1 1 1 TspO/MBR family Pkinase PF00069.20 EMD63246.1 - 1.6e-48 165.0 0.0 2.4e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63246.1 - 6.7e-24 84.3 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD63246.1 - 2.1e-05 24.3 0.1 0.22 11.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EMD63246.1 - 0.0021 17.4 0.1 0.0066 15.8 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EMD63246.1 - 0.0053 15.7 0.0 0.0091 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD63246.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.7 EMD63247.1 - 3.4e-09 36.7 0.2 9.5e-09 35.2 0.3 1.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EMD63247.1 - 5.4e-08 32.5 0.1 0.00086 18.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMD63247.1 - 6.5e-07 28.9 0.3 1.6e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.27 EMD63248.1 - 8.4e-45 149.1 14.9 1.2e-11 43.9 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 EMD63248.1 - 1.9e-14 52.6 2.7 1.9e-14 52.6 1.8 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EMD63248.1 - 1.5e-05 24.7 0.0 1.3 8.6 0.0 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EMD63248.1 - 0.035 13.2 0.0 0.3 10.1 0.0 2.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EMD63248.1 - 0.25 9.4 1.6 6.9 4.6 1.0 3.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 bZIP_Maf PF03131.12 EMD63251.1 - 2.9e-10 40.2 8.4 8.6e-10 38.7 4.8 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EMD63251.1 - 6.4e-07 29.0 10.7 6.4e-07 29.0 7.4 2.2 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EMD63251.1 - 1.1e-06 28.4 7.5 1.1e-06 28.4 5.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor zf-C4H2 PF10146.4 EMD63251.1 - 1.1 9.2 12.0 0.024 14.6 1.4 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein DUF342 PF03961.8 EMD63251.1 - 8.6 4.6 8.0 13 4.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sel1 PF08238.7 EMD63252.1 - 3.8e-21 75.0 6.9 4.7e-08 33.4 0.3 3.5 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EMD63252.1 - 0.014 15.8 4.1 0.23 12.0 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63252.1 - 0.49 11.1 3.0 11 6.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.19 EMD63253.1 - 0.00027 20.5 2.6 0.00027 20.5 1.8 5.6 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SPX PF03105.14 EMD63253.1 - 0.014 15.1 0.2 0.02 14.6 0.1 1.3 1 1 0 1 1 1 0 SPX domain TAFII55_N PF04658.8 EMD63254.1 - 4.2e-47 159.6 0.0 1.1e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF3246 PF11596.3 EMD63254.1 - 0.028 13.7 9.7 0.13 11.4 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Bromo_TP PF07524.8 EMD63255.1 - 1.9e-07 30.7 0.2 7.5e-07 28.7 0.0 2.1 3 0 0 3 3 3 1 Bromodomain associated Phage_int_SAM_4 PF13495.1 EMD63255.1 - 0.033 14.5 0.5 0.093 13.0 0.0 1.9 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain FdhD-NarQ PF02634.10 EMD63256.1 - 0.0065 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 FdhD/NarQ family zf-BED PF02892.10 EMD63257.1 - 2.8e-05 23.7 3.1 0.14 11.9 1.0 2.4 2 0 0 2 2 2 2 BED zinc finger MRP-63 PF14978.1 EMD63257.1 - 0.068 13.6 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 zf-C2H2_4 PF13894.1 EMD63257.1 - 2.3 8.7 6.1 0.33 11.3 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Kisspeptin PF15152.1 EMD63258.1 - 0.49 11.1 4.9 0.84 10.3 0.0 3.3 3 1 0 3 3 3 0 Kisspeptin Lactamase_B PF00753.22 EMD63259.1 - 0.002 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DPPIV_N PF00930.16 EMD63260.1 - 1.3e-108 362.7 0.6 1.8e-108 362.3 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMD63260.1 - 6.3e-55 185.6 1.0 1.1e-54 184.8 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD63260.1 - 5.2e-09 36.0 0.1 1.4e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMD63260.1 - 1.2e-08 34.7 0.3 1.5e-07 31.1 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EMD63260.1 - 6.2e-06 26.2 0.0 6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family SHS2_Rpb7-N PF03876.12 EMD63261.1 - 1.1e-12 47.8 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMD63261.1 - 1.1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EMD63261.1 - 0.0005 20.2 0.0 0.0012 18.9 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 EMD63262.1 - 7.7e-25 86.6 1.2 1.1e-24 86.1 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3852 PF12963.2 EMD63262.1 - 0.23 11.5 1.8 1.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) ATP-synt_ab PF00006.20 EMD63263.1 - 4.2e-71 238.8 0.0 6.8e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMD63263.1 - 3.8e-27 94.9 1.1 1.6e-26 92.9 0.3 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMD63263.1 - 1.8e-16 60.0 2.5 5.8e-16 58.4 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMD63263.1 - 0.0054 16.6 1.2 0.039 13.8 0.1 2.5 2 1 1 3 3 3 1 HAS barrel domain FmdE PF02663.9 EMD63263.1 - 0.1 12.4 0.1 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SNARE_assoc PF09335.6 EMD63264.1 - 2.4e-14 53.6 6.7 2.4e-14 53.6 4.6 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1049 PF06305.6 EMD63264.1 - 0.048 13.1 0.0 0.048 13.1 0.0 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) ATP-synt_E PF05680.7 EMD63264.1 - 0.13 12.2 0.2 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF1771 PF08590.5 EMD63265.1 - 5.3e-13 48.7 8.3 5.3e-13 48.7 5.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EMD63265.1 - 6.5e-08 32.0 6.7 0.0019 17.8 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EMD63265.1 - 2.7e-07 30.6 0.0 7.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Smr domain GAS PF13851.1 EMD63266.1 - 0.022 13.9 3.1 0.04 13.1 2.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF465 PF04325.8 EMD63266.1 - 0.16 11.6 2.1 1.2 8.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) IncA PF04156.9 EMD63266.1 - 1.4 8.4 4.8 5.9 6.4 3.3 2.0 1 1 0 1 1 1 0 IncA protein FAA_hydrolase PF01557.13 EMD63267.1 - 1.6e-51 174.8 0.0 2.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF719 PF05334.8 EMD63268.1 - 0.065 13.2 0.1 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PWI PF01480.12 EMD63269.1 - 1.9e-28 98.3 0.1 3.2e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.13 EMD63269.1 - 0.034 13.5 0.1 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain NAD_binding_8 PF13450.1 EMD63271.1 - 7.5e-12 45.1 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD63271.1 - 2.2e-06 26.7 0.1 3.2e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMD63271.1 - 9e-06 25.0 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMD63271.1 - 4.4e-05 22.5 0.3 0.0001 21.3 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD63271.1 - 0.00018 20.0 0.1 0.00029 19.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMD63271.1 - 0.00024 21.2 0.1 0.0038 17.3 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD63271.1 - 0.00031 20.6 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD63271.1 - 0.00078 18.6 0.0 0.064 12.3 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMD63271.1 - 0.0034 17.7 0.2 0.013 15.8 0.1 2.0 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD63271.1 - 0.0077 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMD63271.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 EMD63271.1 - 0.034 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_9 PF13454.1 EMD63271.1 - 0.045 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMD63271.1 - 0.048 12.2 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase IF-2B PF01008.12 EMD63271.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family TrkA_N PF02254.13 EMD63271.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain HSP70 PF00012.15 EMD63272.1 - 3.1e-232 771.7 13.0 3.5e-232 771.6 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD63272.1 - 2.2e-17 62.6 0.5 1.7e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EMD63272.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain UQ_con PF00179.21 EMD63273.1 - 1.1e-26 92.9 0.1 1.3e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD63273.1 - 6.9e-08 32.3 0.0 1.4e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD63273.1 - 0.002 18.0 0.1 0.0026 17.6 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EMD63273.1 - 0.0083 15.8 0.1 0.009 15.6 0.1 1.2 1 0 0 1 1 1 1 UEV domain Peroxin-13_N PF04088.8 EMD63274.1 - 1.1e-55 187.9 0.2 2e-55 187.1 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 EMD63274.1 - 4e-11 42.1 0.0 6.6e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD63274.1 - 4e-08 32.6 0.0 6.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMD63274.1 - 1.3e-07 31.1 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TniQ PF06527.6 EMD63275.1 - 0.12 12.6 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 TniQ Pkinase PF00069.20 EMD63276.1 - 5e-27 94.6 0.0 5.5e-25 87.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63276.1 - 1.4e-19 70.1 0.0 5.6e-17 61.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.1 EMD63277.1 - 5.2e-82 269.8 17.7 3.5e-14 52.4 0.0 8.6 5 2 2 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 EMD63277.1 - 3.5e-78 255.5 5.4 2.1e-06 27.4 0.0 15.4 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_7 PF13176.1 EMD63277.1 - 1.8e-25 86.6 23.5 0.0023 17.6 0.0 12.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMD63277.1 - 9.4e-24 81.3 20.6 0.096 12.6 0.1 12.4 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMD63277.1 - 1.8e-22 77.9 17.6 0.029 13.9 0.0 11.7 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63277.1 - 1.2e-21 76.8 13.1 0.00051 20.6 0.0 9.6 4 2 5 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMD63277.1 - 1e-19 69.2 21.7 0.11 13.2 0.5 13.2 12 2 3 15 15 15 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD63277.1 - 3.3e-19 68.9 24.6 0.0024 18.1 0.0 8.8 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_4 PF07721.9 EMD63277.1 - 4.1e-19 66.9 6.8 0.055 13.9 0.0 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD63277.1 - 1e-18 66.6 20.0 1.2e-05 24.8 0.0 7.7 4 2 6 11 11 10 6 TPR repeat TPR_8 PF13181.1 EMD63277.1 - 8.1e-15 53.4 14.9 0.25 11.1 0.0 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD63277.1 - 2.6e-14 52.1 8.2 1.1 9.6 0.0 10.3 12 0 0 12 12 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EMD63277.1 - 4.5e-11 42.7 10.4 0.0014 18.7 0.5 6.9 3 1 6 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EMD63277.1 - 7.6e-07 28.6 2.9 2.1 7.6 0.0 5.6 5 1 0 5 5 5 2 26S proteasome subunit RPN7 Tcf25 PF04910.9 EMD63277.1 - 0.00023 20.2 0.0 2.1 7.1 0.1 3.6 2 1 1 3 3 3 1 Transcriptional repressor TCF25 PPR PF01535.15 EMD63277.1 - 0.00026 20.7 9.2 5.9 7.0 0.0 8.9 11 0 0 11 11 10 1 PPR repeat TPR_3 PF07720.7 EMD63277.1 - 0.00051 19.7 0.1 5.1 6.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EMD63277.1 - 0.00098 19.1 12.2 1.5 8.9 0.4 6.6 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD63277.1 - 0.001 19.3 17.9 10 6.8 0.1 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat PPR_3 PF13812.1 EMD63277.1 - 0.0041 17.3 2.0 24 5.5 0.0 5.9 6 0 0 6 6 5 0 Pentatricopeptide repeat domain Peripla_BP_2 PF01497.13 EMD63277.1 - 0.041 13.0 0.1 0.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein TPR_5 PF12688.2 EMD63277.1 - 0.3 11.1 9.8 1.7 8.6 0.2 4.4 4 2 0 4 4 3 0 Tetratrico peptide repeat Acetyltransf_1 PF00583.19 EMD63278.1 - 2e-05 24.5 0.9 9.5e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD63278.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD63278.1 - 0.00057 19.7 0.1 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD63278.1 - 0.0015 18.6 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD63278.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.1 EMD63278.1 - 0.092 12.4 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Ribosomal_S13_N PF08069.7 EMD63279.1 - 4e-28 97.0 0.2 7.3e-28 96.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EMD63279.1 - 3.6e-21 74.7 0.0 5.6e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EMD63279.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_32 PF13565.1 EMD63279.1 - 0.051 14.3 0.0 0.099 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Dpy-30 PF05186.8 EMD63280.1 - 5e-12 45.0 0.2 8.6e-12 44.3 0.2 1.4 1 0 0 1 1 1 1 Dpy-30 motif zf-Dof PF02701.10 EMD63283.1 - 2.2 8.2 7.0 1.3 8.9 3.0 1.9 1 1 1 2 2 2 0 Dof domain, zinc finger Rad17 PF03215.10 EMD63284.1 - 3.9e-63 213.8 0.0 6e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EMD63284.1 - 0.002 18.9 0.0 0.0063 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMD63284.1 - 0.003 17.6 0.0 0.0074 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMD63284.1 - 0.0063 16.1 0.1 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD63284.1 - 0.0066 16.1 0.0 0.025 14.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EMD63284.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EMD63284.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EMD63284.1 - 0.014 15.6 0.0 0.035 14.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMD63284.1 - 0.025 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus HA PF03457.9 EMD63284.1 - 0.081 13.0 0.3 0.22 11.6 0.2 1.7 1 0 0 1 1 1 0 Helicase associated domain ABC_tran PF00005.22 EMD63284.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EMD63284.1 - 0.13 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EMD63284.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Exosortase_EpsH PF09721.5 EMD63285.1 - 0.0069 15.6 2.3 0.0082 15.3 1.6 1.0 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF2207 PF09972.4 EMD63285.1 - 0.39 9.2 1.5 0.45 9.0 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_cc PF11790.3 EMD63286.1 - 1.7e-62 210.9 1.5 1.9e-62 210.8 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 EMD63286.1 - 0.05 12.3 0.0 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 DUF3844 PF12955.2 EMD63289.1 - 9e-36 122.0 3.8 1.5e-35 121.4 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_3 PF12947.2 EMD63289.1 - 3.4 7.6 9.6 6.4 6.8 6.7 1.5 1 0 0 1 1 1 0 EGF domain Sec66 PF09802.4 EMD63290.1 - 5.1e-77 257.5 0.5 5.9e-77 257.3 0.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 FUSC PF04632.7 EMD63290.1 - 0.29 9.5 2.1 0.4 9.0 1.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPL4 PF05021.10 EMD63291.1 - 1.6e-125 418.3 0.0 2e-125 417.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EMD63291.1 - 7.2e-70 233.3 0.1 1.1e-69 232.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EMD63291.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AAA PF00004.24 EMD63292.1 - 1.2e-14 54.6 0.0 4.7e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMD63292.1 - 4e-13 49.3 0.0 7.4e-07 28.9 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EMD63292.1 - 6.5e-10 38.3 0.0 7.6e-08 31.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EMD63292.1 - 9.9e-10 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EMD63292.1 - 1.6e-07 31.5 0.0 5.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD63292.1 - 1.9e-06 27.0 0.1 6.1e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EMD63292.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD63292.1 - 1.9e-05 24.3 0.0 5.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMD63292.1 - 2.1e-05 24.5 0.0 0.00064 19.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 EMD63292.1 - 0.00052 19.0 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EMD63292.1 - 0.00064 18.7 0.0 0.0038 16.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EMD63292.1 - 0.001 18.3 0.0 0.0059 15.7 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EMD63292.1 - 0.002 17.7 0.9 0.0085 15.6 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD63292.1 - 0.0028 18.4 0.0 0.0083 16.9 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMD63292.1 - 0.0053 16.6 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD63292.1 - 0.0076 15.9 0.1 0.063 12.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD63292.1 - 0.015 14.6 0.0 0.069 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMD63292.1 - 0.025 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD63292.1 - 0.035 13.5 0.0 0.098 12.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EMD63292.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMD63292.1 - 0.039 13.5 0.0 0.21 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EMD63292.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EMD63292.1 - 0.051 13.1 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EMD63292.1 - 0.061 12.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.8 EMD63292.1 - 0.066 11.9 0.0 0.45 9.1 0.0 2.1 3 0 0 3 3 3 0 TIP49 C-terminus AAA_10 PF12846.2 EMD63292.1 - 0.077 12.4 0.1 1.7 7.9 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EMD63292.1 - 0.079 12.6 0.0 0.37 10.4 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EMD63292.1 - 0.084 12.7 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EMD63292.1 - 0.086 11.6 0.0 2.1 7.0 0.0 2.1 1 1 1 2 2 2 0 SNF2 family N-terminal domain DNA_pol3_delta PF06144.8 EMD63292.1 - 0.089 12.2 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 EMD63292.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IncA PF04156.9 EMD63295.1 - 0.02 14.4 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 IncA protein Protocadherin PF08374.6 EMD63295.1 - 0.089 12.4 2.9 2.7 7.5 0.1 2.2 1 1 1 2 2 2 0 Protocadherin DUF2254 PF10011.4 EMD63295.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) CKS PF01111.14 EMD63296.1 - 8.2e-37 124.8 0.3 1.1e-36 124.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EMD63296.1 - 0.038 13.9 1.0 0.75 9.9 0.1 2.6 2 0 0 2 2 2 0 APC 15 residue motif Paired_CXXCH_1 PF09699.5 EMD63297.1 - 0.19 11.2 2.0 1.9 8.0 0.2 2.2 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Fungal_trans PF04082.13 EMD63299.1 - 8e-25 87.1 0.0 7.8e-24 83.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63299.1 - 0.00011 22.0 6.9 0.0002 21.2 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EMD63299.1 - 0.083 13.1 0.6 0.25 11.6 0.4 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2235 PF09994.4 EMD63301.1 - 2.7e-73 246.7 0.0 3.8e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EMD63301.1 - 0.042 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SMP PF04927.7 EMD63302.1 - 8.2e-07 28.8 12.9 0.022 14.7 0.1 3.4 3 0 0 3 3 3 3 Seed maturation protein LRR_6 PF13516.1 EMD63303.1 - 2.9e-10 39.1 5.9 0.15 12.2 0.0 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EMD63303.1 - 8.3e-10 38.0 11.2 0.065 12.8 0.1 5.9 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMD63303.1 - 0.00098 18.8 2.7 14 6.1 0.0 6.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 EMD63303.1 - 0.0025 17.5 6.6 0.97 9.2 0.0 4.2 3 2 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EMD63303.1 - 0.16 12.2 4.0 25 5.6 0.0 5.2 6 0 0 6 6 6 0 Leucine rich repeat Radial_spoke PF04712.7 EMD63303.1 - 9.9 4.7 11.6 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Alg6_Alg8 PF03155.10 EMD63304.1 - 1.5e-128 429.5 21.5 6e-82 275.9 7.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 EMD63305.1 - 5.1e-45 150.9 0.0 4.4e-22 77.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63305.1 - 3.4e-33 113.4 0.0 1.1e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63305.1 - 1.6e-23 82.3 0.0 1.8e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD63305.1 - 0.001 18.8 0.0 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.1 EMD63305.1 - 0.001 18.7 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMD63305.1 - 0.078 12.8 3.3 0.31 10.9 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif MIP-T3 PF10243.4 EMD63305.1 - 0.31 9.4 56.4 0.42 9.0 39.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MFS_1 PF07690.11 EMD63306.1 - 1.8e-17 63.1 24.7 1.8e-17 63.1 17.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63306.1 - 7.8e-06 24.7 9.2 7.8e-06 24.7 6.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter zf-C2H2 PF00096.21 EMD63308.1 - 0.0034 17.6 5.2 0.0034 17.6 3.6 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD63308.1 - 0.45 10.9 19.9 0.071 13.4 2.4 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD63308.1 - 3.5 8.0 11.8 16 5.9 1.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain HECT_2 PF09814.4 EMD63309.1 - 1.3e-74 251.0 0.0 1.6e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 EMD63309.1 - 0.018 14.8 0.6 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon 3Beta_HSD PF01073.14 EMD63310.1 - 1.9e-69 233.4 0.0 2.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD63310.1 - 1.3e-31 109.8 0.1 1.7e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMD63310.1 - 6.4e-18 64.5 0.0 9.4e-15 54.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMD63310.1 - 3e-12 46.0 0.0 4.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMD63310.1 - 1.3e-10 41.6 0.1 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD63310.1 - 5e-10 38.7 0.1 2.4e-09 36.5 0.1 2.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.5 EMD63310.1 - 2.9e-08 33.6 0.4 1.7e-07 31.0 0.3 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EMD63310.1 - 1.8e-07 31.2 0.4 1.3e-06 28.4 0.3 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMD63310.1 - 1.4e-06 27.7 0.1 2.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EMD63310.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UQ_con PF00179.21 EMD63311.1 - 1.1e-41 141.5 0.0 7.7e-29 99.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD63311.1 - 1.7e-06 27.8 0.0 2.7e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EMD63311.1 - 0.035 14.0 0.0 0.89 9.4 0.0 2.5 2 1 0 2 2 2 0 RWD domain UEV PF05743.8 EMD63311.1 - 0.076 12.6 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 UEV domain Sybindin PF04099.7 EMD63312.1 - 1.6e-42 144.5 0.0 1.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EMD63312.1 - 2.1e-10 40.5 0.1 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4478 PF14793.1 EMD63312.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) VWA_2 PF13519.1 EMD63313.1 - 1.9e-11 44.3 0.1 2.6e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EMD63313.1 - 6.4e-06 25.8 0.0 8.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EMD63313.1 - 0.066 12.8 0.3 0.066 12.8 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 EMD63314.1 - 4.7e-10 38.6 1.2 7.3e-10 38.0 0.8 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DHH PF01368.15 EMD63315.1 - 9.8e-12 44.7 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 EMD63315.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 DHHA2 domain DUF2985 PF11204.3 EMD63316.1 - 7.6e-30 102.5 6.4 1.4e-29 101.6 4.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) HLH PF00010.21 EMD63317.1 - 2.4e-16 59.1 0.2 5.3e-16 58.0 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 EMD63321.1 - 7.9e-40 136.6 0.0 4.9e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63321.1 - 1.5e-17 63.5 0.0 2.4e-16 59.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD63321.1 - 2.2e-06 27.6 0.0 4.8e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD63321.1 - 0.044 12.7 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF1796 PF08795.5 EMD63322.1 - 0.04 13.5 0.3 0.07 12.7 0.2 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Glyco_transf_8 PF01501.15 EMD63323.1 - 7.1e-26 91.0 0.0 9.6e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMD63323.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Sec63 PF02889.11 EMD63324.1 - 2.2e-187 621.7 0.1 9.6e-102 340.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMD63324.1 - 3.1e-52 176.4 0.1 1.6e-29 102.5 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EMD63324.1 - 6.8e-15 55.3 0.0 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMD63324.1 - 2.1e-10 40.2 0.0 1.5e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SUI1 PF01253.17 EMD63325.1 - 1.7e-23 82.2 0.2 3.5e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EMD63325.1 - 0.026 14.4 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Fib_alpha PF08702.5 EMD63325.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Glyco_transf_22 PF03901.12 EMD63326.1 - 8.1e-39 133.7 20.9 1.4e-38 133.0 14.5 1.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family zf-DHHC PF01529.15 EMD63327.1 - 2.3e-36 124.8 0.6 2.3e-36 124.8 0.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EMD63327.1 - 0.019 14.7 0.7 0.044 13.5 0.5 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pex2_Pex12 PF04757.9 EMD63327.1 - 0.028 13.8 0.7 0.044 13.1 0.5 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF3329 PF11808.3 EMD63327.1 - 0.088 12.9 0.1 0.35 10.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) CBFD_NFYB_HMF PF00808.18 EMD63328.1 - 4.4e-29 100.3 1.4 6.7e-29 99.7 0.9 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD63328.1 - 2.3e-07 30.8 0.1 3.8e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EMD63328.1 - 0.00056 19.6 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMD63328.1 - 0.00099 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated HrpB4 PF09502.5 EMD63328.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) TFIID_20kDa PF03847.8 EMD63328.1 - 0.027 14.7 0.2 0.065 13.5 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 EMD63330.1 - 7.7e-24 83.4 10.4 9.8e-24 83.1 7.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EMD63330.1 - 0.0045 16.6 10.2 0.33 10.6 7.1 2.2 1 1 0 1 1 1 1 Prefoldin subunit UBN2 PF14223.1 EMD63330.1 - 0.023 14.4 3.2 0.076 12.8 0.4 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Mer2 PF09074.5 EMD63330.1 - 0.025 14.4 1.7 0.025 14.4 1.2 2.0 1 1 1 2 2 2 0 Mer2 DASH_Dad3 PF08656.5 EMD63330.1 - 0.027 14.1 1.3 0.027 14.1 0.9 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Borrelia_lipo_1 PF05714.6 EMD63330.1 - 0.046 12.8 0.5 0.046 12.8 0.3 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein STAT_alpha PF01017.15 EMD63330.1 - 0.048 13.3 8.6 0.06 13.0 6.0 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain SMK-1 PF04802.10 EMD63330.1 - 0.073 12.5 0.6 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Component of IIS longevity pathway SMK-1 p25-alpha PF05517.7 EMD63330.1 - 0.073 13.3 2.7 0.95 9.7 0.1 2.1 2 0 0 2 2 2 0 p25-alpha DUF4200 PF13863.1 EMD63330.1 - 0.11 12.4 6.5 0.36 10.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 EMD63330.1 - 0.11 12.0 7.1 0.22 11.1 4.9 1.4 1 1 0 1 1 1 0 Mnd1 family DUF4559 PF15112.1 EMD63330.1 - 0.12 11.4 5.3 0.14 11.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tho2 PF11262.3 EMD63330.1 - 0.14 11.2 5.3 4.7 6.1 3.6 2.0 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.14 EMD63330.1 - 0.16 9.7 3.4 0.18 9.6 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1374 PF07118.6 EMD63330.1 - 0.19 11.8 3.4 1.1 9.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) GAS PF13851.1 EMD63330.1 - 0.2 10.8 11.2 0.32 10.1 7.7 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC PF05010.9 EMD63330.1 - 0.22 11.2 6.3 0.28 10.9 4.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Cystatin PF00031.16 EMD63330.1 - 0.26 11.4 2.6 0.22 11.6 0.3 1.9 2 0 0 2 2 2 0 Cystatin domain DUF2205 PF10224.4 EMD63330.1 - 0.27 10.8 8.3 1.5 8.4 0.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Syntaxin-6_N PF09177.6 EMD63330.1 - 0.29 11.5 5.4 2.5 8.5 0.7 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4201 PF13870.1 EMD63330.1 - 0.39 10.1 8.4 0.5 9.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.7 EMD63330.1 - 0.4 10.4 5.9 0.3 10.8 0.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF2089 PF09862.4 EMD63330.1 - 0.44 10.3 3.4 1.9 8.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) WXG100 PF06013.7 EMD63330.1 - 0.51 10.3 5.6 0.69 9.9 1.3 2.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF4337 PF14235.1 EMD63330.1 - 0.59 9.9 7.6 0.63 9.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MADF_DNA_bdg PF10545.4 EMD63330.1 - 0.6 10.3 2.8 1.4 9.1 1.2 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FliJ PF02050.11 EMD63330.1 - 0.95 9.5 11.3 3.6 7.6 2.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF948 PF06103.6 EMD63330.1 - 1.3 8.9 4.7 3.9 7.4 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EMD63330.1 - 1.8 8.7 10.4 2.2 8.3 7.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EMD63330.1 - 2.4 8.2 7.5 4 7.4 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YkuI_C PF10388.4 EMD63330.1 - 2.6 7.6 5.9 4.8 6.8 0.3 2.0 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain bZIP_Maf PF03131.12 EMD63330.1 - 8.2 6.7 7.8 9.9 6.5 0.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Spc24 PF08286.6 EMD63330.1 - 9.4 5.9 11.9 7.2 6.3 1.8 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Cmc1 PF08583.5 EMD63331.1 - 3.2e-16 58.8 3.4 3.7e-16 58.6 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like RPN7 PF10602.4 EMD63331.1 - 0.00025 20.4 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 NDUF_B7 PF05676.8 EMD63331.1 - 0.042 13.2 1.1 0.058 12.8 0.8 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) bZIP_1 PF00170.16 EMD63331.1 - 1.3 9.0 7.9 0.24 11.3 3.1 1.5 2 0 0 2 2 2 0 bZIP transcription factor NTR2 PF15458.1 EMD63332.1 - 4.3e-62 209.6 19.3 4.3e-62 209.6 13.4 1.5 2 0 0 2 2 2 1 Nineteen complex-related protein 2 IncA PF04156.9 EMD63332.1 - 0.18 11.3 5.7 0.031 13.8 1.4 1.7 2 0 0 2 2 2 0 IncA protein LSM PF01423.17 EMD63333.1 - 4e-18 64.7 0.4 4.7e-18 64.5 0.3 1.1 1 0 0 1 1 1 1 LSM domain Cas_NE0113 PF09623.5 EMD63333.1 - 0.078 12.4 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) APH PF01636.18 EMD63334.1 - 9.5e-38 130.2 0.0 1.7e-37 129.4 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD63334.1 - 2e-06 27.1 0.0 4.7e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EMD63334.1 - 0.00094 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMD63334.1 - 0.0052 16.1 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EMD63334.1 - 0.0071 15.4 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAP_GLY PF01302.20 EMD63335.1 - 3.5e-17 61.8 1.0 6.7e-17 60.9 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain NPV_P10 PF05531.7 EMD63335.1 - 0.0067 16.6 4.5 0.85 9.9 0.3 2.9 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EMD63335.1 - 0.23 9.8 15.6 0.041 12.3 5.4 2.2 1 1 1 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 EMD63335.1 - 0.26 11.0 28.3 0.076 12.7 5.4 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EMD63335.1 - 0.39 10.5 2.8 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EMD63335.1 - 0.47 9.0 23.0 0.11 11.1 4.9 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF812 PF05667.6 EMD63335.1 - 0.48 8.8 22.5 0.18 10.3 9.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DELLA PF12041.3 EMD63335.1 - 0.58 9.8 3.4 2 8.1 0.5 2.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Fib_alpha PF08702.5 EMD63335.1 - 1.6 8.8 9.8 16 5.6 0.9 3.6 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-CCHC_4 PF14392.1 EMD63335.1 - 2.1 8.0 4.4 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle Occludin_ELL PF07303.8 EMD63335.1 - 3.3 8.4 10.6 0.42 11.3 0.9 3.2 3 0 0 3 3 3 0 Occludin homology domain Lectin_N PF03954.9 EMD63335.1 - 4.8 6.5 5.4 9.8 5.5 0.1 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain EMP24_GP25L PF01105.19 EMD63335.1 - 6.8 6.3 6.6 1.2 8.7 1.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlxA PF14282.1 EMD63335.1 - 8.6 6.3 15.2 6.9 6.6 0.8 3.5 3 0 0 3 3 3 0 FlxA-like protein Laps PF10169.4 EMD63335.1 - 8.6 6.6 9.2 0.22 11.7 0.8 2.4 2 0 0 2 2 2 0 Learning-associated protein GNAT_acetyltr_2 PF13718.1 EMD63337.1 - 2.8e-81 271.5 0.0 9.7e-81 269.7 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EMD63337.1 - 1.2e-65 220.4 0.0 3.9e-65 218.7 0.0 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EMD63337.1 - 7.5e-40 134.5 0.0 2.3e-39 132.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EMD63337.1 - 1.2e-32 112.0 0.9 2.8e-32 110.8 0.6 1.7 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EMD63337.1 - 0.0017 18.4 1.0 0.028 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMD63337.1 - 0.0074 16.0 0.8 0.43 10.3 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain Acetyltransf_7 PF13508.1 EMD63337.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S9 PF00326.16 EMD63338.1 - 9.7e-53 178.5 0.2 1.5e-52 177.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD63338.1 - 4.5e-09 36.2 0.1 7.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EMD63338.1 - 0.00013 21.5 3.8 0.031 13.9 0.1 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PhoD PF09423.5 EMD63339.1 - 5.5e-09 35.1 0.1 2.1e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 EMD63340.1 - 9e-54 182.5 3.4 9e-54 182.5 2.4 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EMD63340.1 - 1.5e-27 95.2 0.2 2.7e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain RTC PF01137.16 EMD63341.1 - 3e-34 117.7 0.1 4.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EMD63341.1 - 2.8e-32 110.7 0.0 1.1e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC4 PF14474.1 EMD63342.1 - 4.8e-27 94.3 0.0 9.1e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain GTP_EFTU PF00009.22 EMD63343.1 - 1.1e-42 145.6 0.0 1.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMD63343.1 - 7.7e-26 90.0 0.0 3.1e-25 88.0 0.0 2.1 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.19 EMD63343.1 - 7.9e-17 60.9 0.0 2.1e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD63343.1 - 1.8e-08 34.3 0.6 7.2e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMD63343.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EMD63343.1 - 0.00014 22.3 0.1 0.00035 21.0 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMD63343.1 - 0.036 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.5 EMD63343.1 - 0.1 11.8 0.1 0.99 8.5 0.1 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 EMD63344.1 - 2.2e-97 325.1 0.1 3.1e-97 324.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD63344.1 - 1.4e-43 147.2 3.1 2.5e-42 143.1 1.8 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMD63344.1 - 8.4e-05 22.1 3.0 0.0077 15.7 1.3 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMD63344.1 - 0.00023 20.7 3.7 0.012 15.2 0.0 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 EMD63344.1 - 0.016 13.6 0.2 0.031 12.7 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 EMD63344.1 - 0.016 15.0 1.3 16 5.3 0.0 3.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Glyco_hydro_16 PF00722.16 EMD63345.1 - 9.4e-10 38.0 0.1 2.5e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 HET PF06985.6 EMD63346.1 - 5.2e-16 59.0 0.0 1.1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Telomere_reg-2 PF10193.4 EMD63347.1 - 1.4e-38 131.6 0.1 4.7e-38 129.9 0.1 2.0 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 EMD63348.1 - 1.3e-37 128.6 0.5 2.6e-37 127.6 0.1 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EMD63348.1 - 7e-29 99.4 0.1 1.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EMD63348.1 - 6.7e-24 83.2 1.1 1.5e-23 82.1 0.8 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMD63348.1 - 1.4e-14 53.1 2.7 1.4e-14 53.1 1.8 2.6 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EMD63348.1 - 2.5e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMD63348.1 - 0.066 13.6 0.1 0.32 11.4 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.3 EMD63348.1 - 0.1 12.4 1.0 0.21 11.5 0.7 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.13 EMD63348.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EMD63348.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 EMD63348.1 - 0.19 10.5 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase APC_CDC26 PF10471.4 EMD63350.1 - 7.5e-13 49.0 8.3 9e-13 48.7 5.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 DUF3484 PF11983.3 EMD63350.1 - 0.0093 16.7 3.4 0.011 16.4 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3484) Selenoprotein_S PF06936.6 EMD63350.1 - 0.021 14.3 2.9 0.024 14.1 2.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Exonuc_X-T_C PF08411.5 EMD63350.1 - 0.096 11.6 3.0 0.11 11.5 2.1 1.0 1 0 0 1 1 1 0 Exonuclease C-terminal IncFII_repA PF02387.10 EMD63350.1 - 0.11 11.6 2.1 0.11 11.6 1.4 1.0 1 0 0 1 1 1 0 IncFII RepA protein family MRP-S27 PF10037.4 EMD63350.1 - 0.31 9.9 5.5 0.34 9.7 3.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF1682 PF07946.9 EMD63350.1 - 2 7.1 7.0 2.1 7.1 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2406 PF10295.4 EMD63351.1 - 1.5e-22 79.8 0.2 5.9e-22 77.9 0.1 2.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aldedh PF00171.17 EMD63353.1 - 6.1e-136 453.4 0.4 7.5e-136 453.1 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 EMD63354.1 - 2.9e-167 555.9 18.4 2.9e-167 555.9 12.8 2.0 2 0 0 2 2 2 1 Calreticulin family DUF1752 PF08550.5 EMD63355.1 - 2.6e-06 26.9 3.1 5.3e-06 25.9 2.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.11 EMD63357.1 - 2.2e-51 174.6 52.5 8.3e-49 166.1 36.0 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD63357.1 - 8.3e-21 73.8 13.4 8.3e-21 73.8 9.3 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD63357.1 - 1.9e-15 56.4 9.6 1.9e-15 56.4 6.6 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter NDUFB10 PF10249.4 EMD63358.1 - 0.0004 20.5 0.1 0.00047 20.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EMD63358.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase BRO1 PF03097.13 EMD63359.1 - 8.4e-11 41.2 0.0 1.7e-10 40.2 0.0 1.4 2 0 0 2 2 2 1 BRO1-like domain AA_permease_2 PF13520.1 EMD63361.1 - 1e-49 169.2 56.4 1.3e-49 168.8 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD63361.1 - 1.6e-12 46.5 48.5 2.5e-12 45.8 33.5 1.4 1 1 0 1 1 1 1 Amino acid permease zf-H2C2_5 PF13909.1 EMD63363.1 - 0.33 11.2 0.4 0.33 11.2 0.3 1.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2232 PF09991.4 EMD63369.1 - 0.082 11.8 1.1 0.09 11.7 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SPDY PF03771.11 EMD63369.1 - 0.096 12.1 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Asp_Glu_race PF01177.17 EMD63369.1 - 2.4 7.9 5.7 9.8 6.0 3.9 1.8 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase zf-C2H2_2 PF12756.2 EMD63370.1 - 8.1e-08 32.3 17.1 0.0076 16.3 2.4 4.0 2 1 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMD63370.1 - 3.2e-06 27.1 29.9 0.00014 21.9 1.6 6.4 5 1 1 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMD63370.1 - 5.8e-06 26.3 29.9 0.015 15.6 1.2 6.8 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-DBF PF07535.7 EMD63370.1 - 0.019 14.6 8.7 0.49 10.1 0.3 4.0 4 0 0 4 4 4 0 DBF zinc finger zf-met PF12874.2 EMD63370.1 - 0.02 15.0 2.4 0.02 15.0 1.7 6.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMD63370.1 - 0.033 14.4 30.9 0.36 11.2 0.2 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EMD63370.1 - 0.051 13.0 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF4024 PF13216.1 EMD63370.1 - 0.081 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Zn-ribbon_8 PF09723.5 EMD63370.1 - 4.3 7.3 11.7 12 5.9 0.2 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMD63370.1 - 5.8 6.9 24.0 2.4 8.1 1.0 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger DNase_NucA_NucB PF14040.1 EMD63372.1 - 3.8e-27 94.6 1.1 5.4e-27 94.2 0.8 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Abhydrolase_6 PF12697.2 EMD63373.1 - 0.00032 20.6 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EMD63373.1 - 0.00051 19.9 0.1 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ferric_reduct PF01794.14 EMD63374.1 - 2.8e-18 66.1 12.2 2.8e-18 66.1 8.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD63374.1 - 1.4e-13 51.0 0.2 4.3e-12 46.2 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD63374.1 - 3.9e-09 36.3 0.0 0.003 17.4 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_10 PF13460.1 EMD63375.1 - 2e-12 47.5 0.1 3.2e-11 43.5 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMD63375.1 - 5.5e-10 39.0 0.0 9.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD63375.1 - 8.8e-06 24.6 0.0 2.8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMD63375.1 - 0.0032 16.7 0.1 0.0094 15.2 0.0 1.8 2 1 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EMD63375.1 - 0.038 12.9 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 EMD63375.1 - 0.23 11.3 1.9 0.76 9.6 0.1 2.5 2 1 0 2 2 2 0 short chain dehydrogenase Mem_trans PF03547.13 EMD63376.1 - 2.1e-25 88.8 2.5 3.2e-25 88.2 1.7 1.2 1 0 0 1 1 1 1 Membrane transport protein Glyco_hydro_31 PF01055.21 EMD63377.1 - 1.6e-80 271.0 0.2 2.1e-80 270.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EMD63378.1 - 4.9e-28 97.8 32.9 4.9e-28 97.8 22.8 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3357 PF11837.3 EMD63378.1 - 0.026 14.3 0.0 0.09 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Vpu PF00558.14 EMD63378.1 - 6.2 6.4 9.0 5.4 6.6 1.1 3.2 3 1 0 3 3 3 0 Vpu protein Zn_clus PF00172.13 EMD63379.1 - 1.9e-10 40.4 10.7 3.3e-10 39.6 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 EMD63379.1 - 0.015 13.7 2.4 0.026 12.9 1.6 1.3 1 0 0 1 1 1 0 Per os infectivity FAD_binding_3 PF01494.14 EMD63380.1 - 1.6e-16 60.3 3.2 1.3e-14 54.0 2.2 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD63380.1 - 0.00069 19.5 0.0 0.0035 17.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TraO PF10626.4 EMD63380.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO DEAD PF00270.24 EMD63381.1 - 1.2e-28 99.6 0.1 2.1e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD63381.1 - 8.6e-18 63.9 0.0 2.1e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMD63381.1 - 0.0087 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3987 PF13148.1 EMD63381.1 - 0.054 12.0 3.3 0.082 11.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ResIII PF04851.10 EMD63381.1 - 0.099 12.4 1.6 0.21 11.4 1.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RRN3 PF05327.6 EMD63381.1 - 0.51 8.3 1.5 0.82 7.7 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Anillin PF08174.6 EMD63382.1 - 7.7e-33 113.4 0.1 4.7e-32 110.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EMD63382.1 - 2.7e-09 37.1 0.0 7.1e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMD63382.1 - 0.014 15.6 0.1 0.048 13.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Nucleoplasmin PF03066.10 EMD63383.1 - 0.1 12.1 4.5 0.19 11.2 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin SR-25 PF10500.4 EMD63383.1 - 2.9 7.2 24.5 0.09 12.2 8.5 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nucleocapsid-N PF11030.3 EMD63383.1 - 3.2 7.5 6.1 8.8 6.0 4.2 1.7 1 0 0 1 1 1 0 Nucleocapsid protein N Rotamase PF00639.16 EMD63386.1 - 3.7e-22 78.8 0.2 5.8e-22 78.2 0.2 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EMD63386.1 - 1.5e-15 57.4 0.1 4.6e-15 55.9 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EMD63386.1 - 3.7e-08 33.0 1.2 6.5e-08 32.2 0.9 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EMD63386.1 - 2.5e-07 31.3 0.1 5.4e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain Ribosomal_L20 PF00453.13 EMD63386.1 - 0.048 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L20 TFIIS_C PF01096.13 EMD63387.1 - 4.1e-13 48.7 2.7 4.1e-13 48.7 1.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMD63387.1 - 1.1e-09 37.7 3.2 1.1e-09 37.7 2.2 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EMD63387.1 - 0.0051 16.6 9.0 0.43 10.4 0.8 2.5 2 1 0 2 2 2 2 Double zinc ribbon Nudix_N_2 PF14803.1 EMD63387.1 - 0.031 13.9 7.3 1.7 8.4 0.3 3.3 3 0 0 3 3 3 0 Nudix N-terminal RPA_interact_C PF14768.1 EMD63387.1 - 0.15 12.5 7.6 3.9 7.9 1.3 2.6 2 1 1 3 3 3 0 Replication protein A interacting C-terminal YhfH PF14149.1 EMD63387.1 - 0.34 10.7 0.2 0.34 10.7 0.2 2.7 3 0 0 3 3 3 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.2 EMD63387.1 - 0.52 10.1 7.8 0.29 10.9 0.5 2.6 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-UBP PF02148.14 EMD63387.1 - 0.77 9.9 5.9 4.1 7.6 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein OrfB_Zn_ribbon PF07282.6 EMD63387.1 - 1.1 9.0 6.5 9 6.0 0.4 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 EMD63387.1 - 1.4 8.4 10.2 2.7 7.5 0.2 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Lar_restr_allev PF14354.1 EMD63387.1 - 1.5 9.1 9.2 1.5 9.2 0.9 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 EMD63387.1 - 1.7 8.0 7.2 3.4 7.0 2.4 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.9 EMD63387.1 - 2 8.3 9.0 2.3 8.2 0.8 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EMD63387.1 - 2.2 8.2 7.2 1.4e+02 2.4 4.0 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RRN7 PF11781.3 EMD63387.1 - 4.6 6.8 18.0 8 6.0 0.1 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 FYVE PF01363.16 EMD63387.1 - 4.8 7.1 8.7 1.3 8.9 0.4 2.4 2 1 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 EMD63387.1 - 4.9 6.9 9.7 0.29 10.8 0.4 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 EMD63387.1 - 6.6 6.0 13.5 13 5.1 0.0 3.5 4 0 0 4 4 3 0 zinc-ribbon domain ADK_lid PF05191.9 EMD63387.1 - 6.6 6.4 8.3 11 5.7 0.1 3.5 4 0 0 4 4 4 0 Adenylate kinase, active site lid C1_4 PF07975.7 EMD63387.1 - 8.6 6.4 9.6 1.8 8.6 0.7 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Ribosomal_L14 PF00238.14 EMD63388.1 - 1.8e-46 156.8 2.7 2e-46 156.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EMD63389.1 - 3.5e-11 43.6 1.1 4.4e-09 36.8 0.0 3.2 3 1 0 3 3 3 2 SET domain DUF4360 PF14273.1 EMD63390.1 - 1.1e-09 38.1 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF1775 PF07987.6 EMD63390.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) DUF2428 PF10350.4 EMD63392.1 - 1.1e-68 231.0 0.1 3.8e-68 229.2 0.0 1.9 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EMD63392.1 - 2.7e-08 33.2 11.4 0.53 10.5 0.1 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 EMD63392.1 - 0.0062 16.7 10.9 6 7.2 0.3 6.2 7 1 1 8 8 8 3 HEAT repeats HEAT_EZ PF13513.1 EMD63392.1 - 0.028 14.9 8.3 0.2 12.1 0.6 4.5 4 0 0 4 4 4 0 HEAT-like repeat MBOAT PF03062.14 EMD63393.1 - 1.2e-20 73.8 13.7 2.2e-20 73.0 9.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMD63393.1 - 7.3e-06 25.9 0.5 3e-05 23.9 0.3 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 EMD63394.1 - 4.4e-48 159.5 15.8 9.7e-09 34.7 0.6 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EMD63394.1 - 0.00057 19.6 0.2 0.051 13.2 0.1 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EMD63394.1 - 0.1 11.3 0.1 0.53 8.9 0.1 2.0 2 1 0 3 3 3 0 Nup133 N terminal like HK PF02110.10 EMD63395.1 - 5e-73 245.3 0.8 5e-73 245.3 0.6 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EMD63395.1 - 7.1e-55 184.8 1.6 1.2e-54 184.1 1.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EMD63395.1 - 0.006 15.8 1.7 0.0082 15.4 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EMD63395.1 - 0.042 13.0 1.8 0.046 12.9 0.1 1.9 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.12 EMD63396.1 - 1.9e-39 134.1 0.0 3.3e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EMD63396.1 - 2.2e-21 75.5 2.8 2.2e-21 75.5 1.9 1.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EMD63396.1 - 0.15 12.0 1.2 0.39 10.7 0.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF914 PF06027.7 EMD63397.1 - 1.6e-105 352.7 20.0 1.9e-105 352.4 13.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMD63397.1 - 0.0041 17.1 13.4 0.0041 17.1 9.3 2.8 2 1 1 3 3 3 1 EamA-like transporter family HCV_env PF01539.12 EMD63397.1 - 0.041 13.3 1.9 0.081 12.3 1.3 1.5 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 PAT1 PF09770.4 EMD63398.1 - 3 5.9 29.8 4.5 5.3 20.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_2 PF13639.1 EMD63399.1 - 1.2e-08 34.6 1.3 1.2e-08 34.6 0.9 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD63399.1 - 4.9e-06 26.1 0.6 4.9e-06 26.1 0.4 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD63399.1 - 7.1e-06 25.5 0.6 7.1e-06 25.5 0.4 2.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMD63399.1 - 1.2e-05 24.8 18.6 1.8e-05 24.3 7.2 2.6 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 EMD63399.1 - 1.3e-05 25.2 2.8 1.3e-05 25.2 2.0 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMD63399.1 - 4e-05 23.2 0.2 4e-05 23.2 0.2 3.2 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD63399.1 - 4.5e-05 23.3 0.7 4.5e-05 23.3 0.5 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EMD63399.1 - 0.00019 20.6 7.0 0.00048 19.3 4.9 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.1 EMD63399.1 - 0.01 15.3 0.6 0.028 13.9 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EMD63399.1 - 0.013 15.3 0.3 0.013 15.3 0.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger UxaC PF02614.9 EMD63399.1 - 0.02 13.5 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucuronate isomerase zf-RING_4 PF14570.1 EMD63399.1 - 0.053 13.0 0.1 0.053 13.0 0.1 2.3 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF1649 PF07855.7 EMD63399.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) Saccharop_dh PF03435.13 EMD63400.1 - 3.4e-25 88.8 0.0 1.9e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase Med22 PF06179.7 EMD63401.1 - 1.2e-05 25.3 0.1 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Sec3_C PF09763.4 EMD63402.1 - 0.75 7.8 3.9 0.82 7.7 2.7 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 SMK-1 PF04802.10 EMD63404.1 - 1.4e-76 256.3 3.7 3.2e-76 255.1 2.6 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 EMD63404.1 - 0.041 12.9 0.1 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D DUF1299 PF06975.6 EMD63404.1 - 0.053 13.4 1.2 0.19 11.5 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) DHFR_1 PF00186.14 EMD63405.1 - 1.2e-26 93.1 0.0 1.1e-25 90.0 0.0 2.2 1 1 0 1 1 1 1 Dihydrofolate reductase MAPEG PF01124.13 EMD63406.1 - 3.6e-17 62.1 4.9 4.2e-17 61.9 3.4 1.1 1 0 0 1 1 1 1 MAPEG family Lipase_3 PF01764.20 EMD63407.1 - 1.4e-20 73.3 0.0 2.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) 1-cysPrx_C PF10417.4 EMD63407.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Voltage_CLC PF00654.15 EMD63409.1 - 3.5e-90 302.5 28.9 6.1e-90 301.7 20.0 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel ADH_N PF08240.7 EMD63409.1 - 4.7e-26 90.6 2.2 1e-25 89.6 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD63409.1 - 2.4e-18 65.9 0.4 5e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CBS PF00571.23 EMD63409.1 - 3.9e-07 29.7 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain ADH_zinc_N_2 PF13602.1 EMD63409.1 - 5.4e-05 24.0 0.0 0.00014 22.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Y_phosphatase3 PF13350.1 EMD63409.1 - 0.044 14.0 0.0 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family peroxidase PF00141.18 EMD63410.1 - 1.1e-84 283.5 0.0 3.3e-43 147.8 0.0 2.5 2 1 0 2 2 2 2 Peroxidase Peptidase_M48 PF01435.13 EMD63414.1 - 3.8e-37 128.0 0.0 6.6e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Cutinase PF01083.17 EMD63415.1 - 5.5e-25 88.1 0.9 9.2e-25 87.4 0.7 1.4 1 0 0 1 1 1 1 Cutinase DUF3500 PF12006.3 EMD63416.1 - 1e-91 307.1 0.0 1.2e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.14 EMD63417.1 - 1e-15 57.6 0.1 1.4e-14 53.9 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD63417.1 - 8.3e-08 32.1 0.3 1.9e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD63417.1 - 2.4e-06 26.7 1.7 0.00012 21.1 1.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD63417.1 - 4.1e-05 22.6 3.4 7.5e-05 21.7 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD63417.1 - 0.00026 21.1 0.2 0.0012 18.9 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMD63417.1 - 0.00031 20.5 0.1 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.9 EMD63417.1 - 0.00036 20.4 1.6 0.00072 19.4 0.8 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD63417.1 - 0.0009 19.5 0.0 0.01 16.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD63417.1 - 0.0064 15.6 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD63417.1 - 0.0067 16.2 1.0 0.027 14.2 0.3 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EMD63417.1 - 0.0098 14.7 1.1 0.014 14.3 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EMD63417.1 - 0.0099 14.9 0.4 0.016 14.2 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EMD63417.1 - 0.011 14.4 0.4 0.015 13.9 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EMD63417.1 - 0.049 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMD63417.1 - 0.17 11.6 1.0 0.3 10.8 0.7 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EMD63417.1 - 0.23 11.5 1.1 0.68 10.0 0.7 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EMD63417.1 - 0.29 9.5 1.4 0.52 8.7 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 EMD63417.1 - 0.3 11.5 2.8 1.2 9.6 0.5 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 EMD63418.1 - 4.7e-40 137.3 23.6 7.1e-40 136.7 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63418.1 - 2.5e-10 39.5 7.8 2.5e-10 39.5 5.4 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Anoctamin PF04547.7 EMD63418.1 - 0.012 14.3 0.1 0.034 12.8 0.1 1.7 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF4231 PF14015.1 EMD63418.1 - 0.1 12.5 2.4 1.3 9.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) AMP-binding PF00501.23 EMD63419.1 - 0.0021 16.5 0.0 0.0023 16.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_108 PF05838.7 EMD63419.1 - 0.003 17.6 0.1 0.1 12.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase 108 gpW PF02831.10 EMD63419.1 - 0.086 12.4 0.1 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 gpW AA_permease PF00324.16 EMD63420.1 - 3.8e-44 150.8 31.4 1.5e-43 148.8 21.8 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD63420.1 - 3.7e-23 81.7 23.2 4.8e-23 81.3 16.1 1.1 1 0 0 1 1 1 1 Amino acid permease Ubiq_cyt_C_chap PF03981.7 EMD63422.1 - 3.2e-35 121.0 1.3 4.5e-35 120.5 0.9 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone mRNA_cap_enzyme PF01331.14 EMD63424.1 - 1.7e-46 158.3 0.0 2.7e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EMD63424.1 - 3.4e-17 62.6 0.0 7.1e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EMD63424.1 - 1.4e-06 27.8 0.0 2.5e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 ATP dependent DNA ligase domain PHF5 PF03660.9 EMD63425.1 - 6.6e-51 170.8 9.9 7.4e-51 170.7 6.9 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EMD63425.1 - 0.45 10.3 16.1 0.051 13.4 5.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EMD63425.1 - 1.8 8.3 15.4 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EMD63425.1 - 8.4 3.9 6.8 1.5 6.4 2.5 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 Pinin_SDK_memA PF04696.8 EMD63426.1 - 8e-22 77.2 13.3 8e-22 77.2 9.2 1.8 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 EMD63427.1 - 3.3e-30 105.6 0.0 6.1e-30 104.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63427.1 - 1.1e-20 74.2 0.0 3.3e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63427.1 - 7.3e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 EMD63428.1 - 2.1e-27 95.0 0.5 4.2e-27 94.0 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD63428.1 - 4.3e-16 58.6 0.5 7.9e-16 57.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMD63428.1 - 0.032 13.6 0.2 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain JAB PF01398.16 EMD63429.1 - 1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMD63429.1 - 0.0033 17.4 0.0 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Pyr_redox_3 PF13738.1 EMD63433.1 - 7.6e-31 107.7 0.0 1.7e-30 106.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD63433.1 - 1e-18 66.8 0.0 2.2e-16 59.1 0.0 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD63433.1 - 5.9e-14 51.7 0.8 1.5e-09 37.2 0.0 3.9 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD63433.1 - 1.1e-11 44.9 0.0 8.8e-09 35.5 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD63433.1 - 3.7e-09 35.9 0.1 4.7e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD63433.1 - 1.4e-07 31.4 0.0 4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD63433.1 - 8.6e-07 28.8 0.1 0.0018 18.0 0.0 3.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMD63433.1 - 0.00019 20.3 0.1 0.00038 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMD63433.1 - 0.00032 19.7 0.0 0.00077 18.4 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EMD63433.1 - 0.0077 16.3 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EMD63433.1 - 0.012 14.6 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 EMD63433.1 - 0.039 14.2 0.0 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EMD63433.1 - 0.058 13.8 0.1 3 8.3 0.3 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMD63433.1 - 0.15 11.1 0.0 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3445 PF11927.3 EMD63434.1 - 1.7e-74 250.3 0.0 2.4e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NmrA PF05368.8 EMD63435.1 - 2e-32 112.3 0.0 7.2e-32 110.5 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD63435.1 - 3.1e-10 40.3 0.0 4.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EMD63435.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EMD63435.1 - 0.028 13.1 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD63435.1 - 0.038 13.4 0.0 0.055 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD63435.1 - 0.1 12.4 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_47 PF01532.15 EMD63436.1 - 2.5e-172 573.6 0.0 2.8e-172 573.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med20 PF08612.6 EMD63437.1 - 5.5e-13 48.5 0.1 9.2e-13 47.8 0.1 1.3 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF3580 PF12117.3 EMD63437.1 - 0.12 12.3 0.9 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) RRM_1 PF00076.17 EMD63438.1 - 4.6e-39 131.9 0.0 5.9e-12 45.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63438.1 - 4.8e-38 128.9 0.0 1.3e-09 37.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63438.1 - 8e-18 64.0 0.0 0.00034 20.4 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EMD63438.1 - 1.1e-13 50.5 5.5 1.1e-13 50.5 3.8 3.5 3 0 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 EMD63438.1 - 0.0011 18.8 3.2 0.15 11.9 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.6 EMD63438.1 - 0.0078 16.1 0.4 0.49 10.4 0.0 3.7 4 0 0 4 4 4 1 RNA binding domain DUF4523 PF15023.1 EMD63438.1 - 0.032 13.7 0.0 5.3 6.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Suf PF05843.9 EMD63438.1 - 9.4 5.8 12.9 0.35 10.5 4.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Alg6_Alg8 PF03155.10 EMD63439.1 - 2.4e-137 458.5 26.6 3.4e-137 458.0 18.5 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EMD63439.1 - 6.9e-32 109.6 0.8 6.9e-32 109.6 0.5 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EMD63439.1 - 4.8e-12 45.4 0.6 1e-11 44.4 0.4 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EMD63439.1 - 1.2e-07 31.3 0.1 3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EMD63439.1 - 0.00011 21.9 0.8 0.00011 21.9 0.6 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 Glycophorin_A PF01102.13 EMD63439.1 - 0.44 10.3 3.5 0.67 9.7 0.0 2.8 2 0 0 2 2 2 0 Glycophorin A SCA7 PF08313.7 EMD63440.1 - 2.3e-33 113.6 0.5 2.3e-33 113.6 0.3 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Hexokinase_2 PF03727.11 EMD63441.1 - 1.7e-88 295.9 0.0 3.5e-88 294.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 EMD63441.1 - 6.1e-75 251.0 0.0 9.8e-75 250.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase adh_short PF00106.20 EMD63442.1 - 9.2e-15 54.9 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMD63442.1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMD63442.1 - 1.8e-05 24.4 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD63442.1 - 0.0048 16.9 0.1 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DIM PF08194.7 EMD63443.1 - 0.0057 16.5 2.9 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 DIM protein Cyclase PF04199.8 EMD63444.1 - 2.6e-16 59.7 0.0 3.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase RabGAP-TBC PF00566.13 EMD63445.1 - 1.1e-47 162.2 0.0 9.4e-46 155.9 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3220 PF11516.3 EMD63445.1 - 0.071 13.0 1.1 1.4 8.8 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3120) RRM_1 PF00076.17 EMD63446.1 - 4e-34 116.0 0.3 8.1e-17 60.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63446.1 - 6.2e-27 93.3 0.1 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63446.1 - 1e-09 38.1 0.1 3.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD63446.1 - 0.1 12.4 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 EMD63446.1 - 0.11 12.3 0.0 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TMEM156 PF15106.1 EMD63446.1 - 0.29 10.3 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family Glyco_hydro_16 PF00722.16 EMD63448.1 - 1.8e-43 148.0 1.3 2.7e-43 147.3 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Aldedh PF00171.17 EMD63449.1 - 1.4e-10 40.0 5.2 1.3e-05 23.7 1.7 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 EMD63449.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) NAD_binding_8 PF13450.1 EMD63450.1 - 3e-10 39.9 0.0 1e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMD63450.1 - 6e-09 35.4 0.0 5.2e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMD63450.1 - 5.6e-06 26.5 0.3 5.6e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD63450.1 - 0.00031 19.7 0.0 0.088 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD63450.1 - 0.0046 16.8 0.1 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD63450.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMD63450.1 - 0.027 14.2 0.4 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMD63450.1 - 0.029 13.4 0.6 0.042 12.9 0.1 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EMD63450.1 - 0.035 12.5 0.1 0.11 10.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EMD63450.1 - 0.09 11.6 0.6 0.19 10.6 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EMD63450.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.2 EMD63450.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPT PF03151.11 EMD63451.1 - 4.7e-25 88.0 8.8 4.7e-25 88.0 6.1 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMD63451.1 - 8.3e-07 28.2 18.5 8.2e-05 21.6 1.2 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EMD63451.1 - 0.051 13.6 33.3 0.037 14.0 7.7 2.7 3 0 0 3 3 3 0 EamA-like transporter family DUF914 PF06027.7 EMD63451.1 - 1.8 7.3 16.0 1.9 7.2 9.9 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Ribosomal_L18e PF00828.14 EMD63452.1 - 5.2e-15 55.9 0.1 5.2e-15 55.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 AIRC PF00731.15 EMD63453.1 - 1.9e-57 192.7 0.0 3.9e-57 191.7 0.0 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EMD63453.1 - 1.8e-55 186.9 0.0 3.4e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMD63453.1 - 1.9e-14 53.7 0.0 4.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMD63453.1 - 5.6e-05 22.6 0.0 0.00032 20.1 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EMD63453.1 - 7.5e-05 22.1 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.1 EMD63453.1 - 0.00087 19.6 0.4 0.024 14.9 0.1 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EMD63453.1 - 0.0018 17.4 0.1 0.0033 16.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMD63453.1 - 0.005 16.6 0.2 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATPgrasp_Ter PF15632.1 EMD63453.1 - 0.013 14.2 0.0 0.75 8.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon 3HCDH_N PF02737.13 EMD63453.1 - 0.015 14.9 0.6 0.031 13.9 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.9 EMD63453.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain Luteo_P1-P2 PF08467.5 EMD63453.1 - 0.035 12.9 0.1 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase VirE_N PF08800.5 EMD63453.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 VirE N-terminal domain GFO_IDH_MocA PF01408.17 EMD63453.1 - 0.1 13.0 0.3 0.29 11.6 0.2 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BsuPI PF12690.2 EMD63454.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Intracellular proteinase inhibitor GMC_oxred_C PF05199.8 EMD63455.1 - 5.5e-26 91.5 0.0 6.3e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMD63456.1 - 1.4e-37 129.4 0.0 2.6e-37 128.5 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD63456.1 - 1.7e-06 27.2 0.0 0.0032 16.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD63456.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD63456.1 - 0.0016 18.3 0.0 0.0054 16.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glyco_transf_34 PF05637.7 EMD63457.1 - 1.1e-12 48.0 0.0 1.5e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family HeLo PF14479.1 EMD63458.1 - 4.8e-06 26.4 1.8 0.0036 17.0 0.0 3.0 2 1 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 EMD63458.1 - 6.1e-05 22.3 0.1 0.00021 20.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63458.1 - 0.028 13.5 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase IQ PF00612.22 EMD63458.1 - 1.1 9.0 4.3 18 5.2 0.7 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif SNase PF00565.12 EMD63459.1 - 2.6e-72 239.9 0.6 7.4e-26 90.5 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EMD63459.1 - 9.4e-26 90.0 0.0 1.9e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain adh_short PF00106.20 EMD63460.1 - 0.03 14.2 0.1 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF2007 PF09413.5 EMD63460.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) SLT_L PF14718.1 EMD63460.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Glyco_hydro_17 PF00332.13 EMD63462.1 - 5.1e-08 32.3 1.6 4.8e-06 25.8 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Herpes_US9 PF06072.6 EMD63462.1 - 0.024 14.4 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Shadoo PF14999.1 EMD63462.1 - 0.3 10.9 14.8 0.034 14.0 6.5 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Gly-zipper_OmpA PF13436.1 EMD63462.1 - 0.32 10.6 16.1 0.93 9.1 5.8 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EMD63462.1 - 8.3 6.1 32.5 11 5.7 6.0 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EMD63462.1 - 9.4 5.8 33.1 3.4 7.2 11.9 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Ferritin_2 PF13668.1 EMD63463.1 - 4.5e-47 159.4 6.0 6.4e-47 158.9 4.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain HTH_psq PF05225.11 EMD63465.1 - 4.1e-11 42.2 0.1 5.3e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EMD63465.1 - 0.028 14.3 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D CENP-B_N PF04218.8 EMD63465.1 - 0.043 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 EMD63465.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain OTT_1508_deam PF14441.1 EMD63466.1 - 1.4e-15 57.3 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF2154 PF09922.4 EMD63466.1 - 0.075 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Cell wall-active antibiotics response protein (DUF2154) NAD_binding_6 PF08030.7 EMD63468.1 - 0.0093 15.8 0.3 0.044 13.6 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Abhydrolase_6 PF12697.2 EMD63469.1 - 3.5e-30 105.5 0.3 3.8e-29 102.1 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD63469.1 - 5.1e-14 52.2 0.0 5.6e-13 48.8 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63469.1 - 1.4e-13 51.0 0.3 1e-12 48.0 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMD63469.1 - 1.4e-09 37.7 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EMD63469.1 - 0.00035 20.0 0.0 0.00055 19.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMD63469.1 - 0.00083 18.6 0.5 0.002 17.3 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Antimicrobial14 PF08109.6 EMD63469.1 - 0.14 11.9 0.7 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Lactocin 705 family DUF3669 PF12417.3 EMD63470.1 - 4.9e-17 61.4 0.3 9.4e-17 60.5 0.2 1.5 1 0 0 1 1 1 1 Zinc finger protein PARP_regulatory PF01358.13 EMD63470.1 - 0.025 13.2 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit DUF1100 PF06500.6 EMD63472.1 - 3.7e-13 48.8 0.0 5.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EMD63472.1 - 6.5e-13 48.6 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD63472.1 - 2.2e-12 47.3 1.8 2.6e-12 47.0 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD63472.1 - 0.00023 20.6 0.0 0.0061 16.0 0.0 2.7 1 1 1 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 EMD63472.1 - 0.0044 16.4 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EMD63472.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EMD63472.1 - 1.4 8.3 3.8 11 5.4 1.0 2.8 3 1 0 4 4 4 0 alpha/beta hydrolase fold tRNA-synt_2 PF00152.15 EMD63473.1 - 4.5e-93 311.6 1.9 6.3e-93 311.1 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EMD63473.1 - 1.4e-06 27.7 0.2 0.0023 17.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EMD63473.1 - 4.8e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EMD63473.1 - 0.0027 17.3 0.3 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.20 EMD63474.1 - 1.3e-40 139.2 0.0 2.3e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63474.1 - 6e-22 77.9 0.0 2.9e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase SGL PF08450.7 EMD63475.1 - 9.7e-23 80.8 0.7 1.9e-22 79.8 0.5 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EMD63475.1 - 7e-05 22.7 0.0 0.00028 20.8 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EMD63475.1 - 9.1e-05 22.3 0.4 0.00038 20.3 0.1 2.3 2 1 0 2 2 2 1 Arylesterase NHL PF01436.16 EMD63475.1 - 0.039 13.9 0.9 8.3 6.5 0.0 3.4 3 0 0 3 3 3 0 NHL repeat PD40 PF07676.7 EMD63475.1 - 0.046 13.4 0.2 0.92 9.2 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 EMD63480.1 - 9.6e-06 24.9 0.0 2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EMD63480.1 - 0.00023 20.2 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EMD63480.1 - 0.0019 17.4 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EMD63480.1 - 0.0021 17.8 1.0 0.013 15.2 0.0 2.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family zf-C2H2 PF00096.21 EMD63481.1 - 2.1e-10 40.2 16.2 4.5e-05 23.5 2.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD63481.1 - 3e-10 39.8 7.9 3.6e-05 23.8 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD63481.1 - 1.1e-06 28.4 11.5 0.044 14.1 0.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger ubiquitin PF00240.18 EMD63482.1 - 1.1e-34 117.6 0.5 1.8e-34 116.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EMD63482.1 - 2.1e-28 97.9 2.4 4.3e-28 96.8 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EMD63482.1 - 4.1e-20 71.2 0.6 7.2e-20 70.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMD63482.1 - 1.7e-05 25.0 0.1 7.5e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMD63482.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMD63482.1 - 0.0012 18.7 0.5 0.0025 17.6 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD63482.1 - 0.0042 17.2 0.3 0.0058 16.7 0.2 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EMD63482.1 - 0.021 14.6 0.5 0.033 14.0 0.3 1.3 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 EMD63482.1 - 0.11 10.8 1.7 2.2 6.4 0.0 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Band_7 PF01145.20 EMD63483.1 - 3.1e-23 82.6 3.1 4.3e-23 82.1 2.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Lectin_leg-like PF03388.8 EMD63484.1 - 2.9e-31 108.3 0.0 4.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Adaptin_binding PF10199.4 EMD63484.1 - 0.00096 19.4 0.7 0.00096 19.4 0.5 1.5 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Atg14 PF10186.4 EMD63484.1 - 0.07 12.0 6.7 0.1 11.5 4.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4088 PF13317.1 EMD63484.1 - 0.1 11.9 1.1 0.17 11.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) DUF812 PF05667.6 EMD63484.1 - 0.61 8.5 10.9 0.14 10.6 4.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) IncA PF04156.9 EMD63484.1 - 0.94 9.0 10.9 1.7 8.1 7.5 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EMD63484.1 - 1.8 8.9 7.7 0.43 10.9 1.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 EMD63484.1 - 2.2 7.8 7.3 0.06 12.9 0.6 1.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Nup54 PF13874.1 EMD63484.1 - 2.4 7.7 10.3 0.19 11.3 2.5 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Amidohydro_1 PF01979.15 EMD63485.1 - 3e-25 89.5 0.1 2.4e-12 47.1 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMD63485.1 - 4.4e-18 66.2 0.0 3e-17 63.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMD63485.1 - 3.1e-09 36.5 0.1 7.5e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD63485.1 - 4.9e-09 35.8 0.0 3.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1917 PF08939.5 EMD63486.1 - 7.5e-52 176.4 0.5 4.6e-50 170.6 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) DNA_primase_S PF01896.14 EMD63487.1 - 2.2e-53 179.9 0.1 5.5e-53 178.6 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit Glyco_hydro_20 PF00728.17 EMD63488.1 - 2.7e-87 293.2 0.0 3.4e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMD63488.1 - 2.4e-21 76.7 0.0 5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMD63488.1 - 0.0038 17.7 0.0 0.0079 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EMD63489.1 - 2.3e-63 214.3 0.0 2.9e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELFV_dehydrog PF00208.16 EMD63490.1 - 7.1e-62 209.1 0.0 2.3e-61 207.4 0.0 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EMD63490.1 - 7e-19 66.8 0.0 5.5e-13 47.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EMD63490.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ppx-GppA PF02541.11 EMD63491.1 - 9.3e-44 149.7 0.0 1.9e-43 148.6 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 EMD63491.1 - 0.0067 14.9 0.0 0.013 14.0 0.0 1.4 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Rft-1 PF04506.8 EMD63492.1 - 5e-95 318.9 12.8 2.3e-93 313.4 8.9 2.0 1 1 0 1 1 1 1 Rft protein Acetyltransf_3 PF13302.1 EMD63493.1 - 8.4e-30 103.7 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMD63493.1 - 0.085 12.8 0.0 2.3 8.1 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Periviscerokin PF08259.6 EMD63494.1 - 0.27 11.4 1.9 30 5.1 0.3 2.9 2 0 0 2 2 2 0 Periviscerokinin family TFIIIC_sub6 PF10419.4 EMD63495.1 - 1.1e-14 53.6 0.1 1.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 EMD63496.1 - 6.1e-11 41.0 0.3 8.4e-11 40.5 0.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) S-AdoMet_synt_C PF02773.11 EMD63498.1 - 1.1e-74 248.6 0.4 1.9e-74 247.9 0.1 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EMD63498.1 - 1.8e-47 160.2 0.0 3.2e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EMD63498.1 - 4e-44 148.9 0.8 7.1e-44 148.1 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 EMD63498.1 - 0.014 13.9 0.3 0.68 8.3 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.12 EMD63499.1 - 1.8e-77 260.0 0.1 2.7e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMD63499.1 - 7.3e-06 26.8 0.0 2.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMD63499.1 - 0.00071 19.4 0.0 0.0022 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMD63499.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 EMD63499.1 - 0.0017 18.2 0.0 0.006 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMD63499.1 - 0.0019 17.6 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD63499.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD63499.1 - 0.0044 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EMD63499.1 - 0.0054 16.6 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD63499.1 - 0.0097 15.3 0.1 0.032 13.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD63499.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EMD63499.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EMD63499.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMD63499.1 - 0.026 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC cobW PF02492.14 EMD63499.1 - 0.029 13.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EMD63499.1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMD63499.1 - 0.033 13.6 0.0 0.075 12.4 0.0 1.6 2 0 0 2 2 1 0 AAA-like domain AAA_18 PF13238.1 EMD63499.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD63499.1 - 0.04 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EMD63499.1 - 0.044 12.5 0.0 0.58 8.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EMD63499.1 - 0.051 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EMD63499.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EMD63499.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EMD63499.1 - 0.11 12.5 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.12 EMD63499.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase GTP_EFTU PF00009.22 EMD63499.1 - 0.13 11.7 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 EMD63499.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMD63499.1 - 0.15 11.7 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EMD63499.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VTC PF09359.5 EMD63500.1 - 1.6e-99 332.4 0.3 1.6e-99 332.4 0.2 2.3 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 EMD63500.1 - 1.4e-23 84.0 16.3 2.4e-11 43.9 0.1 3.9 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.10 EMD63500.1 - 4.5e-09 36.4 4.6 9.5e-09 35.3 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Patatin PF01734.17 EMD63502.1 - 3.7e-19 69.4 0.0 4.9e-18 65.7 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_trans_1_4 PF13692.1 EMD63505.1 - 8.9e-27 93.8 0.3 8.1e-25 87.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMD63505.1 - 2.2e-07 31.1 0.4 5.7e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EMD63505.1 - 9.6e-05 21.8 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMD63505.1 - 0.0092 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EMD63506.1 - 2.7e-54 184.1 4.6 2.7e-54 184.1 3.2 3.0 4 0 0 4 4 4 1 Cation efflux family Zip PF02535.17 EMD63506.1 - 0.00014 20.9 62.9 0.015 14.3 0.0 4.6 2 2 1 3 3 3 2 ZIP Zinc transporter CDC45 PF02724.9 EMD63506.1 - 7.2 4.5 7.4 12 3.7 5.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_E_B PF04042.11 EMD63507.1 - 6.1e-48 162.8 0.2 8.8e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SARG PF15385.1 EMD63507.1 - 0.035 13.4 2.4 0.06 12.7 1.7 1.3 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein SHNi-TPR PF10516.4 EMD63508.1 - 8.3e-20 69.7 1.3 9.4e-16 56.7 0.2 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EMD63508.1 - 7.5e-06 25.8 6.3 0.028 14.3 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD63508.1 - 0.0021 17.6 6.1 0.036 13.6 0.7 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EMD63508.1 - 5.7 7.1 10.1 7.3 6.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 EMD63509.1 - 2.3e-22 79.6 0.2 1.7e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD63509.1 - 6.3e-15 55.6 0.0 2.4e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD63509.1 - 1.1e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD63509.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MaoC_dehydratas PF01575.14 EMD63510.1 - 5.2e-08 32.3 0.0 8.5e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain Zn_clus PF00172.13 EMD63511.1 - 1.3e-08 34.6 11.0 2.2e-08 33.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EMD63512.1 - 1.7e-21 76.0 1.1 3e-21 75.3 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD63512.1 - 4.6e-09 37.2 0.3 1.2e-08 35.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SRP72 PF08492.7 EMD63513.1 - 1.5e-14 54.0 4.9 1.5e-14 54.0 3.4 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EMD63513.1 - 4.5e-08 33.3 27.2 0.045 14.0 2.9 7.5 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63513.1 - 3.4e-07 30.7 20.8 0.018 15.6 0.3 6.1 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD63513.1 - 3.2e-06 27.2 20.9 0.86 10.4 0.1 8.1 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD63513.1 - 0.00073 19.2 24.1 0.13 12.2 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 EMD63513.1 - 0.0017 18.5 10.1 1.8 9.2 0.4 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD63513.1 - 0.0025 17.9 15.9 0.53 10.4 2.5 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EMD63513.1 - 0.0026 17.8 8.5 0.83 9.8 1.4 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat SPO22 PF08631.5 EMD63513.1 - 0.018 14.1 1.5 0.18 10.8 0.1 2.7 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SPOB_a PF14689.1 EMD63513.1 - 0.041 13.4 0.3 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_10 PF13374.1 EMD63513.1 - 0.058 13.3 11.9 1.5 8.8 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMD63513.1 - 0.18 11.6 7.6 1.2 9.0 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD63513.1 - 0.27 11.5 6.9 0.91 9.8 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat CHAD PF05235.9 EMD63513.1 - 0.35 10.4 10.6 0.14 11.6 4.7 2.1 1 1 0 2 2 2 0 CHAD domain TPR_6 PF13174.1 EMD63513.1 - 2.7 8.6 18.0 2.1 9.0 0.9 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TFIIE_alpha PF02002.12 EMD63514.1 - 5.6e-08 32.2 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Myosin_HC-like PF07058.6 EMD63514.1 - 0.0055 15.8 1.2 0.0081 15.2 0.8 1.2 1 0 0 1 1 1 1 Myosin II heavy chain-like Tub PF01167.13 EMD63514.1 - 0.044 12.7 0.4 0.56 9.1 0.1 2.1 2 0 0 2 2 2 0 Tub family Zn-ribbon_8 PF09723.5 EMD63514.1 - 0.1 12.5 0.4 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Nucleoplasmin PF03066.10 EMD63514.1 - 0.22 11.0 6.2 0.58 9.6 4.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin TF_Zn_Ribbon PF08271.7 EMD63514.1 - 0.47 9.8 4.0 0.75 9.1 1.7 2.2 2 1 0 2 2 2 0 TFIIB zinc-binding Nop14 PF04147.7 EMD63514.1 - 0.91 7.3 11.6 1.2 6.9 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.6 EMD63514.1 - 1.1 7.8 5.5 1.7 7.2 3.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.1 EMD63514.1 - 1.9 8.1 6.2 0.79 9.3 1.7 2.1 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.8 EMD63514.1 - 4.2 5.0 11.3 6.7 4.3 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.1 EMD63514.1 - 7.9 6.6 17.4 0.058 13.5 4.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PseudoU_synth_1 PF01416.15 EMD63515.1 - 2.1e-24 85.9 0.0 6.5e-11 42.5 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ku PF02735.11 EMD63516.1 - 1.2e-41 142.3 0.0 2.1e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMD63516.1 - 5.9e-26 91.2 0.0 1.1e-25 90.3 0.0 1.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EMD63516.1 - 4.7e-14 52.6 0.5 4.7e-14 52.6 0.4 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EMD63516.1 - 3.8e-10 39.0 0.1 8.1e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain Flu_M1_C PF08289.6 EMD63516.1 - 0.26 11.3 1.4 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Ferrochelatase PF00762.14 EMD63517.1 - 3.4e-92 308.8 0.0 4e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase HET PF06985.6 EMD63518.1 - 1.3e-25 90.2 4.4 2.1e-25 89.5 3.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1_dh PF00676.15 EMD63519.1 - 3.7e-116 387.0 0.2 4.4e-116 386.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMD63519.1 - 0.00051 19.0 0.0 0.00076 18.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EMD63519.1 - 0.032 13.8 1.6 0.067 12.7 1.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BMC PF00936.14 EMD63519.1 - 0.04 13.6 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 BMC domain EST1_DNA_bind PF10373.4 EMD63520.1 - 5.5e-11 42.1 0.0 2e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain MFS_1 PF07690.11 EMD63521.1 - 4.3e-22 78.3 28.6 5.8e-22 77.8 10.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily HATPase_c PF02518.21 EMD63521.1 - 2.3e-16 59.4 0.0 4.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD63521.1 - 7.9e-16 58.0 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMD63521.1 - 7.8e-14 51.4 0.1 1.9e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.19 EMD63521.1 - 1.4e-08 33.7 1.3 2.6e-08 32.9 0.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EMD63521.1 - 0.023 13.1 7.5 0.0036 15.8 1.2 2.3 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like HATPase_c_2 PF13581.1 EMD63521.1 - 0.025 14.3 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Glycos_transf_2 PF00535.21 EMD63522.1 - 7.8e-22 77.7 0.0 8.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMD63522.1 - 2.4e-07 30.7 0.0 0.024 14.4 0.0 2.7 1 1 1 2 2 2 2 Glycosyltransferase like family 2 DUF1145 PF06611.7 EMD63522.1 - 0.32 10.6 2.6 0.45 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Kelch_3 PF13415.1 EMD63523.1 - 1.3e-21 76.1 12.0 1e-06 28.7 0.1 6.5 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EMD63523.1 - 6.9e-18 64.1 10.3 2.2e-07 30.5 0.1 5.8 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD63523.1 - 1.2e-16 60.2 7.4 0.0058 16.5 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMD63523.1 - 2e-15 56.2 5.6 3.2e-05 23.8 0.0 5.4 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EMD63523.1 - 5e-14 51.5 0.1 0.0013 18.2 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EMD63523.1 - 1.4e-09 37.3 2.3 0.077 12.7 0.0 4.7 5 0 0 5 5 5 3 Kelch motif CoA_transf_3 PF02515.12 EMD63524.1 - 1e-39 135.7 0.0 2.7e-39 134.4 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III p450 PF00067.17 EMD63525.1 - 1.1e-57 195.5 0.0 1.5e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.6 EMD63526.1 - 4.7e-21 75.3 0.2 9.3e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Abhydrolase_3 PF07859.8 EMD63527.1 - 2.4e-22 79.5 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMD63527.1 - 5.3e-22 77.9 0.0 6.2e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) zf-C3HC4_2 PF13923.1 EMD63528.1 - 4.2 7.4 12.1 6.8 6.8 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) P5CR_dimer PF14748.1 EMD63529.1 - 1.9e-33 114.6 2.1 3.5e-33 113.8 1.4 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMD63529.1 - 3.4e-08 33.7 1.6 1.4e-07 31.8 0.2 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EMD63529.1 - 0.062 12.1 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydrogenase CTK3 PF12243.3 EMD63530.1 - 2.6e-52 176.1 1.1 3.5e-52 175.7 0.7 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EMD63530.1 - 2.7e-22 78.5 7.8 6e-22 77.4 5.4 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus HEAT_2 PF13646.1 EMD63530.1 - 0.012 15.9 0.7 0.75 10.1 0.1 2.4 1 1 1 2 2 2 0 HEAT repeats KfrA_N PF11740.3 EMD63530.1 - 0.68 10.3 3.6 0.76 10.2 1.3 2.0 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Ribosomal_L12 PF00542.14 EMD63531.1 - 1.5e-19 69.7 7.1 7.9e-19 67.4 3.8 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EMD63531.1 - 0.013 15.9 2.4 0.013 15.9 1.7 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein CP_ATPgrasp_1 PF04174.8 EMD63531.1 - 0.039 12.5 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp AAA_5 PF07728.9 EMD63532.1 - 2.2e-131 432.4 0.1 2.3e-22 79.1 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EMD63532.1 - 7.1e-30 103.9 0.0 0.0001 22.4 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD63532.1 - 6.9e-29 101.1 0.0 0.00073 20.3 0.0 8.1 7 0 0 7 7 6 6 AAA domain AAA_3 PF07726.6 EMD63532.1 - 7.4e-28 96.7 0.0 8e-10 38.4 0.0 8.1 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD63532.1 - 1.3e-26 93.2 1.6 0.0014 18.7 0.0 8.9 8 1 0 8 8 7 6 AAA domain Sigma54_activ_2 PF14532.1 EMD63532.1 - 9.3e-26 90.5 0.4 0.00074 19.5 0.0 8.3 9 0 0 9 9 7 6 Sigma-54 interaction domain AAA_16 PF13191.1 EMD63532.1 - 5.2e-25 88.5 12.6 0.00027 20.9 0.0 8.7 8 1 0 8 8 7 5 AAA ATPase domain AAA_18 PF13238.1 EMD63532.1 - 6e-23 81.5 0.9 0.0052 17.0 0.0 7.5 7 0 0 7 7 6 5 AAA domain Sigma54_activat PF00158.21 EMD63532.1 - 5e-22 78.1 0.0 0.0014 18.0 0.0 6.7 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_14 PF13173.1 EMD63532.1 - 1.1e-21 77.0 0.0 9.9e-05 22.2 0.0 8.0 8 0 0 8 8 7 3 AAA domain AAA_33 PF13671.1 EMD63532.1 - 1.6e-21 76.6 0.0 0.0039 17.0 0.0 8.1 7 1 0 7 7 6 5 AAA domain T2SE PF00437.15 EMD63532.1 - 1.9e-19 69.6 3.6 0.001 18.0 0.0 6.7 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_19 PF13245.1 EMD63532.1 - 1.4e-17 63.1 3.7 0.023 14.4 0.1 6.7 6 0 0 6 6 6 4 Part of AAA domain RNA_helicase PF00910.17 EMD63532.1 - 1.6e-15 57.1 0.5 0.22 11.7 0.0 6.8 6 0 0 6 6 6 4 RNA helicase Zeta_toxin PF06414.7 EMD63532.1 - 2.6e-14 52.8 2.1 0.12 11.4 0.0 7.9 8 0 0 8 8 8 3 Zeta toxin UPF0079 PF02367.12 EMD63532.1 - 5.7e-14 51.8 1.7 0.11 12.1 0.0 6.2 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EMD63532.1 - 1.4e-13 51.1 4.6 0.068 13.1 0.0 7.5 7 0 0 7 7 6 2 AAA domain ABC_tran PF00005.22 EMD63532.1 - 5.7e-13 49.3 12.8 0.025 14.9 0.0 9.0 9 0 0 9 9 8 3 ABC transporter NACHT PF05729.7 EMD63532.1 - 1.7e-12 47.3 4.5 0.16 11.6 0.0 6.7 7 0 0 7 7 6 4 NACHT domain Mg_chelatase PF01078.16 EMD63532.1 - 2.8e-12 46.2 0.0 0.58 9.2 0.0 9.0 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMD63532.1 - 3.3e-12 45.9 0.5 0.05 12.6 0.0 6.4 6 0 0 6 6 5 2 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 EMD63532.1 - 1.2e-11 44.5 0.5 1.2 8.8 0.0 6.7 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EMD63532.1 - 5e-11 42.7 0.1 0.99 9.0 0.0 6.5 6 0 0 6 6 6 2 Archaeal ATPase AAA_25 PF13481.1 EMD63532.1 - 1.7e-10 40.6 2.9 0.88 8.9 0.0 6.4 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.1 EMD63532.1 - 2.3e-10 39.8 0.8 0.65 9.5 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain Miro PF08477.8 EMD63532.1 - 3.8e-10 40.2 0.2 2.3 8.7 0.0 6.5 5 0 0 5 5 5 1 Miro-like protein IstB_IS21 PF01695.12 EMD63532.1 - 6.6e-10 38.6 1.0 0.54 9.6 0.0 6.4 6 0 0 6 6 6 2 IstB-like ATP binding protein SRP54 PF00448.17 EMD63532.1 - 5e-09 35.8 2.8 1.6 8.1 0.0 5.9 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain KaiC PF06745.8 EMD63532.1 - 1.6e-08 34.0 0.3 0.014 14.5 0.0 5.9 6 0 0 6 6 5 1 KaiC DUF258 PF03193.11 EMD63532.1 - 2.6e-08 33.2 5.5 2.2 7.4 0.0 6.4 7 0 0 7 7 6 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EMD63532.1 - 4.6e-08 32.6 2.2 0.023 14.1 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 EMD63532.1 - 1.7e-07 30.3 0.1 1.9 7.0 0.0 5.1 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 EMD63532.1 - 1.6e-06 28.0 0.1 1.7 8.6 0.0 5.7 5 0 0 5 5 5 1 50S ribosome-binding GTPase cobW PF02492.14 EMD63532.1 - 2.3e-06 27.1 6.2 1 8.7 0.0 6.6 7 0 0 7 7 7 1 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 EMD63532.1 - 3.7e-06 26.3 0.6 2.7 7.1 0.0 5.6 6 0 0 6 6 5 1 PhoH-like protein SRPRB PF09439.5 EMD63532.1 - 4e-06 26.1 0.8 1.1 8.4 0.0 5.8 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 EMD63532.1 - 4.4e-06 26.3 1.0 2.8 7.3 0.0 5.6 6 0 0 6 6 5 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EMD63532.1 - 1.3e-05 24.8 5.4 0.25 10.8 0.0 5.6 6 0 0 6 6 5 1 AAA domain NTPase_1 PF03266.10 EMD63532.1 - 1.9e-05 24.4 7.3 1.2 8.8 0.1 5.8 6 0 0 6 6 5 1 NTPase TIP49 PF06068.8 EMD63532.1 - 2.6e-05 23.1 0.2 0.33 9.5 0.0 4.9 6 0 0 6 6 6 1 TIP49 C-terminus vWA-TerF-like PF10138.4 EMD63532.1 - 0.00011 22.1 0.1 0.00031 20.6 0.1 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus ATP-synt_ab PF00006.20 EMD63532.1 - 0.00027 20.5 0.3 0.94 8.9 0.0 4.4 6 0 0 6 6 4 1 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 EMD63532.1 - 0.00059 19.1 5.0 5.6 6.0 0.0 6.0 7 0 0 7 7 6 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 EMD63532.1 - 0.00071 19.2 21.7 0.17 11.4 0.0 7.9 10 0 0 10 10 6 1 AAA domain ATP_bind_1 PF03029.12 EMD63532.1 - 0.0036 16.8 9.6 4.3 6.8 0.0 6.6 8 0 0 8 8 7 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 EMD63532.1 - 0.0084 15.2 0.7 25 3.8 0.0 4.6 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 APS_kinase PF01583.15 EMD63532.1 - 0.058 13.0 0.5 5.9 6.5 0.0 4.1 5 0 0 5 5 5 0 Adenylylsulphate kinase FeoB_N PF02421.13 EMD63532.1 - 0.1 11.8 2.4 12 5.1 0.1 3.9 4 0 0 4 4 3 0 Ferrous iron transport protein B AAA_6 PF12774.2 EMD63532.1 - 0.17 11.3 0.0 96 2.3 0.0 4.3 6 0 0 6 6 3 0 Hydrolytic ATP binding site of dynein motor region D1 Lactate_perm PF02652.9 EMD63532.1 - 6.5 5.1 0.0 11 4.4 0.0 1.2 1 0 0 1 1 1 0 L-lactate permease Herpes_UL36 PF03586.8 EMD63533.1 - 0.046 12.8 0.1 0.052 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein ADH_zinc_N PF00107.21 EMD63534.1 - 1.4e-26 92.5 0.0 2.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD63534.1 - 9.2e-23 80.0 1.5 9.2e-23 80.0 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.15 EMD63535.1 - 3.1e-46 157.7 0.0 5.9e-46 156.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD63535.1 - 4.8e-12 46.2 0.4 3.5e-11 43.4 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD63535.1 - 0.00038 20.2 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2424 PF10340.4 EMD63535.1 - 0.004 15.8 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_4 PF08386.5 EMD63535.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein ketoacyl-synt PF00109.21 EMD63536.1 - 7.9e-61 205.7 1.3 5.9e-60 202.8 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMD63536.1 - 8e-35 119.2 1.0 4.8e-34 116.7 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMD63536.1 - 1.7e-05 23.9 0.0 9e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD63536.1 - 0.00014 21.3 1.4 0.018 14.4 0.2 3.5 3 1 0 3 3 3 1 Thiolase, C-terminal domain NicO PF03824.11 EMD63537.1 - 8.3e-64 215.6 11.9 8.3e-64 215.6 8.2 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein CAF1 PF04857.15 EMD63538.1 - 4.7e-44 150.6 0.0 7.6e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease SAGA-Tad1 PF12767.2 EMD63538.1 - 1.2 8.7 8.2 2.3 7.8 5.7 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GCR PF02155.10 EMD63539.1 - 0.86 8.2 3.3 0.23 10.1 0.2 1.5 2 0 0 2 2 2 0 Glucocorticoid receptor SpoVR PF04293.8 EMD63539.1 - 7.7 4.7 8.3 11 4.2 5.7 1.2 1 0 0 1 1 1 0 SpoVR like protein PTPLA PF04387.9 EMD63540.1 - 2e-43 147.6 9.9 4.2e-43 146.6 6.9 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Abhydrolase_6 PF12697.2 EMD63541.1 - 1.4e-18 67.6 3.9 1.7e-18 67.3 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63541.1 - 3.5e-09 36.5 0.1 4.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63541.1 - 2.6e-07 30.5 0.2 8.6e-07 28.8 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMD63541.1 - 0.0069 15.8 0.2 0.14 11.6 0.1 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) TPP_enzyme_C PF02775.16 EMD63541.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain COesterase PF00135.23 EMD63542.1 - 2e-89 300.7 0.0 2.6e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD63542.1 - 1.1e-07 31.6 0.0 2.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD63542.1 - 0.003 16.8 0.1 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family EVE PF01878.13 EMD63543.1 - 4e-48 163.0 0.0 6.9e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 EVE domain DUF605 PF04652.11 EMD63543.1 - 1.5 8.1 18.2 1.9 7.8 12.6 1.2 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 EMD63543.1 - 6.7 4.7 12.0 8.7 4.3 8.3 1.1 1 0 0 1 1 1 0 Menin Abhydrolase_6 PF12697.2 EMD63544.1 - 4.4e-26 92.1 0.1 6.8e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63544.1 - 9.2e-14 51.5 0.1 2.2e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63544.1 - 6.1e-09 35.7 0.0 3.9e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMD63544.1 - 0.03 12.7 0.0 0.046 12.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family zf-C3HC4 PF00097.20 EMD63545.1 - 1.4e-07 31.0 6.6 1.4e-07 31.0 4.5 4.6 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD63545.1 - 2.9e-07 30.2 7.6 2.9e-07 30.2 5.3 3.7 4 2 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.1 EMD63545.1 - 3.6e-06 26.6 0.3 3.6e-06 26.6 0.2 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EMD63545.1 - 8.8e-06 25.6 6.8 8.8e-06 25.6 4.7 4.4 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD63545.1 - 0.00012 21.7 5.5 0.00012 21.7 3.8 5.4 5 1 0 5 5 5 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMD63545.1 - 0.00013 21.7 8.1 0.00013 21.7 5.6 3.9 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMD63545.1 - 0.015 15.0 2.2 0.015 15.0 1.5 2.1 2 0 0 2 2 2 0 RING-type zinc-finger SH3_9 PF14604.1 EMD63545.1 - 0.032 13.8 0.5 0.069 12.7 0.3 1.5 1 0 0 1 1 1 0 Variant SH3 domain CpXC PF14353.1 EMD63545.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 0 CpXC protein Collagen PF01391.13 EMD63546.1 - 0.67 9.5 101.5 9.4e+03 -3.8 0.5 4.9 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Hexapep PF00132.19 EMD63547.1 - 4.3e-16 57.5 7.1 3.5e-10 38.9 4.0 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD63547.1 - 2.1e-13 49.5 10.4 1.8e-10 40.2 3.6 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EMD63547.1 - 2.9e-10 40.0 0.0 4.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.9 EMD63548.1 - 2.6e-27 94.8 0.6 5e-27 93.9 0.4 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMD63548.1 - 2.8e-15 56.3 2.9 2.8e-15 56.3 2.0 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMD63548.1 - 2.2e-06 27.1 1.2 3.1e-06 26.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Bac_DnaA_C PF08299.6 EMD63549.1 - 0.063 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HEAT PF02985.17 EMD63551.1 - 0.07 13.2 9.5 3.2 8.0 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat HEAT PF02985.17 EMD63552.1 - 2.4e-05 24.0 1.9 0.017 15.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EMD63552.1 - 0.038 14.4 5.9 0.35 11.4 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Nipped-B_C PF12830.2 EMD63552.1 - 0.072 12.7 0.1 17 5.0 0.0 2.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Cnd1 PF12717.2 EMD63552.1 - 0.1 12.4 0.1 22 4.8 0.0 4.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.27 EMD63553.1 - 9.5e-89 288.4 59.3 1.9e-11 43.3 0.0 12.8 12 1 0 12 12 12 10 WD domain, G-beta repeat NACHT PF05729.7 EMD63553.1 - 9.3e-27 93.7 0.0 1.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD63553.1 - 1.1e-22 80.6 4.7 7.7e-19 68.2 0.3 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CDtoxinA PF03498.9 EMD63553.1 - 1.4e-10 40.6 6.5 0.0089 15.4 0.0 5.2 1 1 4 5 5 5 3 Cytolethal distending toxin A/C family Nup160 PF11715.3 EMD63553.1 - 6e-10 37.8 21.8 0.003 15.7 0.1 5.9 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Asp_decarbox PF02261.11 EMD63553.1 - 7.9e-06 25.4 0.0 0.064 12.8 0.0 5.2 5 2 2 7 7 7 1 Aspartate decarboxylase AAA_22 PF13401.1 EMD63553.1 - 0.0079 16.3 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD63553.1 - 0.012 15.3 0.1 0.072 12.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EMD63553.1 - 0.018 15.0 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 EMD63554.1 - 1.8e-47 161.8 42.8 2.3e-45 154.8 30.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63554.1 - 4.7e-15 55.1 10.3 4.7e-15 55.1 7.2 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EMD63554.1 - 2.5e-05 22.8 3.7 2.5e-05 22.8 2.5 3.5 1 1 2 3 3 3 2 MFS/sugar transport protein DUF4245 PF14030.1 EMD63554.1 - 0.0063 16.2 2.1 0.32 10.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4245) YbgT_YccB PF08173.6 EMD63554.1 - 1.6 8.6 8.0 4.5 7.1 2.6 3.3 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Amidase PF01425.16 EMD63555.1 - 2e-91 307.0 0.1 2.5e-91 306.7 0.1 1.0 1 0 0 1 1 1 1 Amidase DUF2148 PF09918.4 EMD63555.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Polysacc_deac_1 PF01522.16 EMD63556.1 - 2.5e-12 46.4 0.0 4.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase V_ATPase_I PF01496.14 EMD63557.1 - 0.026 12.3 0.2 0.029 12.2 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Arginosuc_synth PF00764.14 EMD63558.1 - 9.7e-49 166.4 0.0 1.2e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EMD63558.1 - 1.8e-05 24.3 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EMD63558.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC 2OG-FeII_Oxy PF03171.15 EMD63559.1 - 2e-12 47.2 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD63559.1 - 4.1e-11 43.4 0.0 7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CN_hydrolase PF00795.17 EMD63560.1 - 1.2e-21 76.8 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EMD63561.1 - 1.5e-19 69.9 46.6 1.5e-19 69.9 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA_SAD PF07973.9 EMD63562.1 - 0.00016 21.5 0.2 0.00039 20.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EMD63562.1 - 0.00035 19.0 0.0 0.00044 18.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) PX PF00787.19 EMD63563.1 - 1.7e-16 60.0 0.0 5.8e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EMD63563.1 - 7.4e-13 48.3 9.7 1.1e-08 34.6 0.8 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1675 PF07897.6 EMD63563.1 - 0.0077 16.1 4.5 0.012 15.4 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) DUF1320 PF07030.7 EMD63563.1 - 0.059 13.1 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Peptidase_C10 PF01640.12 EMD63563.1 - 0.064 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family CAP59_mtransfer PF11735.3 EMD63564.1 - 3.4e-69 232.7 0.0 5e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Zip PF02535.17 EMD63564.1 - 7.9e-32 110.5 18.4 4.1e-25 88.4 6.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF4199 PF13858.1 EMD63564.1 - 8.8e-05 22.4 0.7 0.0003 20.7 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4199) NicO PF03824.11 EMD63564.1 - 0.0079 15.5 16.9 0.0076 15.5 5.5 3.1 3 0 0 3 3 3 2 High-affinity nickel-transport protein GTP_EFTU PF00009.22 EMD63565.1 - 3e-55 186.5 0.0 4.7e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMD63565.1 - 3e-23 81.4 0.0 7.6e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EMD63565.1 - 1.1e-16 60.4 0.0 6.9e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD63565.1 - 2.2e-07 30.8 0.1 6.1e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EMD63565.1 - 0.00017 21.1 0.9 0.0024 17.4 0.0 2.8 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EMD63565.1 - 0.021 14.8 0.0 0.083 12.8 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 EMD63566.1 - 1.7e-14 53.6 10.1 3e-14 52.8 7.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMD63566.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PX domain TPR_1 PF00515.23 EMD63566.1 - 0.051 13.2 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD63566.1 - 0.25 11.3 1.3 16 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 EMD63566.1 - 1.3 8.3 17.4 2.8 7.2 12.0 1.6 1 0 0 1 1 1 0 Vta1 like NST1 PF13945.1 EMD63566.1 - 5.9 6.9 15.3 0.076 13.0 3.4 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Amidase PF01425.16 EMD63567.1 - 3.3e-55 187.7 0.0 4.7e-54 183.9 0.0 2.2 1 1 0 1 1 1 1 Amidase DDE_1 PF03184.14 EMD63569.1 - 7.9e-45 152.6 0.0 6.8e-44 149.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF2435 PF10363.4 EMD63569.1 - 0.024 14.5 0.3 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Patatin PF01734.17 EMD63569.1 - 0.15 11.9 0.2 3.1 7.6 0.2 2.2 1 1 0 1 1 1 0 Patatin-like phospholipase DDE_Tnp_IS240 PF13610.1 EMD63569.1 - 0.23 11.4 1.7 1.3 8.9 1.9 1.7 2 0 0 2 2 2 0 DDE domain HTH_Tnp_Tc5 PF03221.11 EMD63570.1 - 1e-05 25.2 0.0 2.8e-05 23.8 0.0 1.7 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain adh_short_C2 PF13561.1 EMD63571.1 - 7.9e-23 81.4 2.3 1.2e-22 80.8 1.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD63571.1 - 7.1e-15 55.3 5.5 1.2e-14 54.5 3.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD63571.1 - 3.1e-06 26.9 1.0 4.8e-06 26.3 0.3 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMD63571.1 - 0.0068 15.3 0.2 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1772 PF08592.6 EMD63572.1 - 0.0081 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) WSC PF01822.14 EMD63574.1 - 2.7e-08 33.5 13.0 2.7e-08 33.5 9.0 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMD63574.1 - 0.00019 20.6 0.5 0.00019 20.6 0.4 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CcmD PF04995.9 EMD63574.1 - 0.021 14.5 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.15 EMD63574.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EMD63574.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rab5ip PF07019.7 EMD63574.1 - 0.11 12.6 2.1 0.27 11.3 1.4 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) FixQ PF05545.6 EMD63574.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ F-box-like PF12937.2 EMD63575.1 - 2.6e-06 27.0 0.0 7.8e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EMD63575.1 - 0.12 12.1 2.4 1 9.1 0.3 2.9 2 0 0 2 2 2 0 Leucine rich repeat F-box PF00646.28 EMD63575.1 - 3.4 7.4 5.3 0.77 9.4 0.1 2.7 3 1 0 3 3 3 0 F-box domain ArfGap PF01412.13 EMD63576.1 - 9e-32 109.3 0.2 2e-31 108.1 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MMR_HSR1 PF01926.18 EMD63578.1 - 4.1e-13 49.2 0.0 7.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMD63578.1 - 0.00092 18.4 0.2 0.0025 17.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EMD63578.1 - 0.0013 18.0 0.2 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 EMD63578.1 - 0.0029 18.3 0.6 0.098 13.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EMD63578.1 - 0.0074 16.1 0.4 0.073 12.8 0.1 2.2 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EMD63578.1 - 0.014 14.1 0.5 0.03 13.1 0.4 1.6 1 1 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 EMD63578.1 - 0.023 14.8 0.2 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMD63578.1 - 0.03 14.6 0.1 0.03 14.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EMD63578.1 - 0.036 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EMD63578.1 - 0.048 13.3 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EMD63578.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EMD63578.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EMD63578.1 - 0.12 12.9 0.3 0.22 12.0 0.2 1.5 1 0 0 1 1 1 0 Miro-like protein RuvB_N PF05496.7 EMD63578.1 - 0.14 11.1 0.1 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus HET PF06985.6 EMD63580.1 - 5.2e-17 62.3 0.0 5.9e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SAP PF02037.22 EMD63581.1 - 7.3e-10 38.1 0.1 1.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 EMD63581.1 - 0.0036 17.0 0.1 0.0073 16.0 0.1 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Fungal_trans_2 PF11951.3 EMD63582.1 - 5.2e-16 58.2 0.0 1.1e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63582.1 - 3.6e-10 39.5 9.8 5.9e-10 38.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP-L46 PF11788.3 EMD63584.1 - 2.4e-35 121.5 0.1 6.2e-35 120.2 0.1 1.7 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cpn60_TCP1 PF00118.19 EMD63585.1 - 6e-137 457.1 8.8 6.8e-137 457.0 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HAD PF12710.2 EMD63585.1 - 0.034 14.2 0.1 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2250 PF10007.4 EMD63585.1 - 0.14 12.0 0.4 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Abhydrolase_6 PF12697.2 EMD63588.1 - 1.2e-17 64.5 0.6 2e-17 63.8 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63588.1 - 0.0024 17.4 0.3 0.0045 16.5 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63588.1 - 0.026 14.2 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3621 PF12285.3 EMD63588.1 - 0.07 13.2 0.2 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Phyto_Pns9_10 PF05878.6 EMD63589.1 - 0.26 10.2 0.0 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 HNF_C PF09354.5 EMD63589.1 - 1.5 9.9 5.4 0.52 11.4 0.8 2.5 2 0 0 2 2 2 0 HNF3 C-terminal domain zf-C3HC4_3 PF13920.1 EMD63590.1 - 2.2e-08 33.6 6.0 3.5e-08 32.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EMD63590.1 - 2.8e-08 33.2 2.7 5.2e-08 32.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EMD63590.1 - 1.6e-07 31.2 10.5 2.8e-07 30.4 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD63590.1 - 9e-07 28.5 9.0 1.5e-06 27.7 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD63590.1 - 1.1e-06 28.1 10.8 2.1e-06 27.3 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD63590.1 - 1.6e-05 24.6 7.2 2.6e-05 23.9 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EMD63590.1 - 0.0028 17.3 4.3 0.0079 15.8 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMD63590.1 - 0.018 14.8 8.4 0.041 13.7 5.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EMD63590.1 - 0.024 14.7 0.8 0.055 13.5 0.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EMD63590.1 - 0.17 11.4 3.7 0.33 10.5 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ATP-synt_E PF05680.7 EMD63590.1 - 1.9 8.4 6.2 0.71 9.8 1.0 2.3 2 0 0 2 2 2 0 ATP synthase E chain Mcp5_PH PF12814.2 EMD63591.1 - 7.4e-45 151.8 0.1 1.9e-44 150.4 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Isy1 PF06246.7 EMD63592.1 - 8.9e-90 300.5 2.9 1e-89 300.3 2.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family CCDC-167 PF15188.1 EMD63592.1 - 0.084 12.8 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 NdhM PF10664.4 EMD63592.1 - 0.14 12.0 0.3 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M YolD PF08863.5 EMD63592.1 - 0.15 11.9 0.7 0.33 10.8 0.5 1.6 1 0 0 1 1 1 0 YolD-like protein DUF904 PF06005.7 EMD63592.1 - 0.98 9.7 7.8 0.25 11.6 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) UPF0113 PF03657.8 EMD63593.1 - 2.8e-09 36.8 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EMD63593.1 - 0.0092 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 EMD63593.1 - 0.023 14.7 0.0 0.057 13.5 0.0 1.7 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis NOC3p PF07540.6 EMD63594.1 - 6.4e-35 119.3 2.8 1.5e-34 118.1 0.6 2.7 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EMD63594.1 - 1.1e-27 96.5 0.0 1.1e-26 93.1 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Tyrosinase PF00264.15 EMD63595.1 - 7.5e-40 137.4 0.1 9.5e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Lectin_leg-like PF03388.8 EMD63596.1 - 2.5e-66 223.1 0.0 3.3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMD63596.1 - 0.05 12.9 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Legume lectin domain zf-Tim10_DDP PF02953.10 EMD63597.1 - 6.7e-24 82.9 2.4 7.9e-24 82.7 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Endonuclease_NS PF01223.18 EMD63598.1 - 6.7e-59 199.0 0.0 9e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Tir_receptor_C PF07489.6 EMD63598.1 - 0.014 15.1 4.2 0.023 14.4 2.9 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus ThiF PF00899.16 EMD63599.1 - 9.7e-35 119.3 0.3 2.1e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 ThiF family Glyco_hydro_17 PF00332.13 EMD63599.1 - 0.0033 16.5 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Saccharop_dh PF03435.13 EMD63599.1 - 0.0056 15.6 0.1 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EMD63599.1 - 0.0098 15.8 0.3 0.1 12.6 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.1 EMD63599.1 - 0.064 13.5 0.3 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding ApbA PF02558.11 EMD63599.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BCLP PF12304.3 EMD63599.1 - 0.18 11.2 0.2 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Beta-casein like protein ADH_N PF08240.7 EMD63600.1 - 7.9e-24 83.5 3.8 1.2e-23 82.9 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD63600.1 - 2e-20 72.6 0.0 3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD63600.1 - 3.1e-07 31.3 0.0 5.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD63600.1 - 0.004 16.3 0.1 0.0069 15.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMD63600.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 EMD63601.1 - 3e-23 82.8 0.0 3.5e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD63601.1 - 2.7e-15 56.5 0.0 5.4e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63601.1 - 5.6e-13 48.8 0.0 8.7e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 EMD63601.1 - 9.9e-06 24.2 0.0 0.00036 19.1 0.0 2.1 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.13 EMD63601.1 - 0.0032 16.9 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMD63601.1 - 0.0039 16.4 0.5 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EMD63601.1 - 0.0054 16.0 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMD63601.1 - 0.0091 15.4 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.9 EMD63601.1 - 0.017 13.6 0.0 0.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Ndr family Ank PF00023.25 EMD63603.1 - 1.5e-12 46.6 0.1 8e-08 31.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMD63603.1 - 1.8e-11 44.2 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD63603.1 - 1.9e-10 40.9 0.1 3.1e-08 33.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD63603.1 - 2e-05 24.3 0.0 0.0023 18.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EMD63603.1 - 4.6e-05 23.5 0.2 7.1e-05 22.9 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EMD63604.1 - 3.2e-14 52.4 0.4 6e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Ank PF00023.25 EMD63604.1 - 2.8e-12 45.8 0.0 9.2e-07 28.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMD63604.1 - 4.4e-11 42.9 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD63604.1 - 2.8e-10 40.4 0.1 6e-07 29.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD63604.1 - 8.1e-07 28.6 0.0 0.016 15.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 EMD63604.1 - 8.5e-06 25.5 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD63604.1 - 2.3e-05 24.4 0.1 9.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Ank_5 PF13857.1 EMD63604.1 - 0.0012 18.9 0.2 0.035 14.3 0.0 2.8 2 1 1 3 3 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 EMD63604.1 - 0.0039 17.3 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMD63604.1 - 0.0077 15.7 0.0 0.13 11.6 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EMD63604.1 - 0.092 12.5 0.0 0.4 10.4 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EMD63604.1 - 0.15 12.2 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EMD63604.1 - 0.16 12.1 0.0 0.62 10.2 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PH_10 PF15411.1 EMD63605.1 - 1.6e-24 86.3 0.0 2.7e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EMD63605.1 - 2.7e-09 36.9 0.0 7.4e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMD63605.1 - 7.7e-09 35.5 0.1 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EMD63605.1 - 9.3e-08 31.7 8.7 1.8e-07 30.8 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD63605.1 - 0.00023 21.0 8.1 0.00042 20.2 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD63605.1 - 0.003 17.2 8.2 0.0053 16.4 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMD63605.1 - 0.012 15.6 3.1 0.025 14.6 2.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD63605.1 - 0.095 12.3 8.7 0.17 11.5 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EMD63605.1 - 0.12 12.1 1.8 0.27 10.9 1.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING-like PF08746.6 EMD63605.1 - 0.35 10.9 7.8 0.63 10.0 5.4 1.4 1 0 0 1 1 1 0 RING-like domain EF-hand_1 PF00036.27 EMD63606.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMD63606.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMD63606.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMD63606.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMD63606.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMD63606.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMD63606.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMD63606.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EMD63606.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EMD63606.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EMD63606.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EMD63606.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EMD63606.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EMD63606.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EMD63606.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 EMD63606.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EMD63606.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EMD63606.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 EMD63606.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EMD63607.1 - 2.9e-18 65.2 3.4 2.9e-18 65.2 2.4 3.5 4 1 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EMD63607.1 - 1.6e-11 44.2 9.0 7.6e-11 42.0 2.1 2.8 3 0 0 3 3 3 1 Syntaxin EBV-NA3 PF05009.7 EMD63607.1 - 0.011 15.0 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FANCI_S4 PF14678.1 EMD63607.1 - 0.014 14.5 1.2 0.07 12.2 0.1 2.2 2 0 0 2 2 2 0 FANCI solenoid 4 MCPsignal PF00015.16 EMD63607.1 - 0.54 9.7 9.7 0.093 12.2 0.3 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2762 PF10960.3 EMD63607.1 - 1.8 8.3 7.9 3.9 7.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) GrpE PF01025.14 EMD63607.1 - 4.8 6.6 8.8 1 8.9 2.2 2.1 2 0 0 2 2 2 0 GrpE DUF829 PF05705.9 EMD63609.1 - 3.7e-52 177.4 0.1 4.3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Mpv17_PMP22 PF04117.7 EMD63610.1 - 4.5e-19 67.8 0.4 1.1e-18 66.6 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ser_hydrolase PF06821.8 EMD63610.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Serine hydrolase Copper-bind PF00127.15 EMD63611.1 - 0.00013 22.0 0.3 0.00023 21.3 0.2 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EMD63611.1 - 0.0099 15.6 0.6 0.13 12.0 0.4 2.3 1 1 0 1 1 1 1 Plastocyanin-like domain MGC-24 PF05283.6 EMD63611.1 - 0.72 9.6 10.9 1.2 8.8 7.6 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Cerato-platanin PF07249.7 EMD63612.1 - 8.7e-58 193.5 1.0 1.1e-57 193.1 0.7 1.1 1 0 0 1 1 1 1 Cerato-platanin PsbY PF06298.6 EMD63612.1 - 0.065 12.7 1.0 0.15 11.6 0.7 1.6 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Transformer PF06495.6 EMD63613.1 - 0.089 12.6 0.8 0.1 12.5 0.5 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Ecl1 PF12855.2 EMD63614.1 - 3.7e-16 58.1 3.1 7.4e-16 57.1 2.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EMD63614.1 - 0.0048 16.7 1.4 0.0098 15.7 1.0 1.4 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EMD63614.1 - 0.03 13.6 1.4 0.07 12.4 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF581) Methyltransf_16 PF10294.4 EMD63616.1 - 8.8e-20 70.8 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMD63616.1 - 9.1e-06 24.9 0.2 1.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMD63616.1 - 7.5e-05 22.1 0.1 0.00013 21.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMD63616.1 - 0.0004 20.9 0.0 0.00071 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMD63616.1 - 0.059 12.9 0.6 0.11 12.0 0.4 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 EMD63616.1 - 0.073 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EMD63617.1 - 1.4e-35 120.9 0.2 2.4e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e YL1 PF05764.8 EMD63618.1 - 1.5e-54 185.1 26.5 1.5e-54 185.1 18.4 1.8 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EMD63618.1 - 3.1e-11 42.5 0.0 5.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Thioredoxin_3 PF13192.1 EMD63618.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain PUF PF00806.14 EMD63620.1 - 2.9e-24 83.1 0.0 0.00014 21.1 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EMD63620.1 - 4.3e-12 45.4 0.0 8.2e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63620.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63620.1 - 2.1e-07 30.7 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Autophagy_N PF03986.8 EMD63621.1 - 1.4e-44 151.4 0.6 1.9e-44 150.9 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EMD63621.1 - 5.4e-24 84.1 0.2 1e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EMD63621.1 - 1.5e-14 52.7 0.4 2.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DNA_pol_B_thumb PF14791.1 EMD63623.1 - 3.2e-21 74.7 0.0 6.3e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EMD63623.1 - 2.4e-19 68.5 1.4 5.3e-19 67.5 0.9 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EMD63623.1 - 1.1e-17 64.0 0.0 2.7e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EMD63623.1 - 3.1e-08 33.6 0.0 3.2e-07 30.4 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EMD63623.1 - 0.027 14.6 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EMD63623.1 - 0.04 14.2 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain FA_desaturase PF00487.19 EMD63624.1 - 3.1 7.1 12.8 3.8 6.8 4.8 2.2 1 1 1 2 2 2 0 Fatty acid desaturase DUF4336 PF14234.1 EMD63625.1 - 7.2e-17 61.4 0.1 2e-13 50.1 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) RNase_PH PF01138.16 EMD63626.1 - 2.1e-20 73.3 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMD63626.1 - 4.6e-09 36.0 0.0 8.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EMD63627.1 - 8.9e-82 274.4 19.4 9.9e-82 274.3 13.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EMD63627.1 - 5.5 4.9 16.0 6.9 4.5 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HNF-1_N PF04814.8 EMD63627.1 - 8.5 6.4 9.2 9.7 6.2 4.7 2.1 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus M_domain PF12938.2 EMD63628.1 - 0.019 14.8 4.3 0.023 14.5 3.0 1.1 1 0 0 1 1 1 0 M domain of GW182 PI3_PI4_kinase PF00454.22 EMD63629.1 - 1e-29 103.6 0.0 2.9e-29 102.2 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EMD63629.1 - 1.6e-18 66.2 0.3 3.3e-18 65.1 0.2 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF155 PF02582.9 EMD63630.1 - 9.3e-55 185.2 1.5 1.8e-54 184.2 1.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Peptidase_M14 PF00246.19 EMD63631.1 - 1.5e-67 228.1 0.0 2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EMD63632.1 - 1.4e-38 132.5 0.1 2.3e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMD63632.1 - 1e-06 28.9 0.1 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMD63632.1 - 8.1e-06 25.9 0.1 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PH domain CW_binding_2 PF04122.7 EMD63633.1 - 0.069 13.3 0.2 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 Clr5 PF14420.1 EMD63634.1 - 9.4e-15 54.2 0.0 2.2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain HIG_1_N PF04588.8 EMD63635.1 - 0.064 13.0 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Hypoxia induced protein conserved region MFS_1 PF07690.11 EMD63636.1 - 9.6e-18 64.0 40.9 4.1e-16 58.6 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD63636.1 - 0.00026 19.7 34.1 0.0087 14.6 18.6 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF4231 PF14015.1 EMD63636.1 - 3.5 7.6 8.8 0.94 9.4 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) F-box-like PF12937.2 EMD63637.1 - 5.3e-07 29.2 0.4 2.4e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EMD63637.1 - 0.0023 17.5 0.9 0.03 13.9 0.2 3.0 2 1 0 2 2 2 1 F-box domain Glyco_hydro_43 PF04616.9 EMD63638.1 - 1.4e-33 116.2 4.9 1.9e-33 115.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Aminotran_5 PF00266.14 EMD63639.1 - 8.9e-59 199.0 0.0 1.8e-58 198.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMD63639.1 - 1.4e-05 23.5 0.0 2.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD63639.1 - 0.00032 19.7 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4113 PF13438.1 EMD63639.1 - 0.13 11.9 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Terpene_synth_C PF03936.11 EMD63640.1 - 0.027 13.7 0.0 0.074 12.2 0.0 1.7 1 1 1 2 2 2 0 Terpene synthase family, metal binding domain Tyrosinase PF00264.15 EMD63643.1 - 7.4e-45 153.8 0.2 9.2e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase ALMT PF11744.3 EMD63644.1 - 2 6.9 5.6 3.1 6.3 3.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Fijivirus_P9-2 PF06837.6 EMD63644.1 - 2.8 7.0 6.9 4.3 6.4 4.8 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF2570 PF10828.3 EMD63645.1 - 0.0023 17.4 11.5 0.0055 16.2 0.4 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2570) Cep57_CLD_2 PF14197.1 EMD63645.1 - 0.017 15.0 1.3 0.017 15.0 0.9 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 IncA PF04156.9 EMD63645.1 - 0.069 12.7 0.2 0.069 12.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein Methyltransf_2 PF00891.13 EMD63646.1 - 2.9e-35 121.5 0.0 3.7e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMD63646.1 - 0.00046 20.7 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD63646.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD63646.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMD63646.1 - 0.033 14.5 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMD63646.1 - 0.049 14.1 0.0 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MarR_2 PF12802.2 EMD63646.1 - 0.078 12.6 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 MarR family Methyltransf_12 PF08242.7 EMD63646.1 - 0.099 13.1 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HTH_24 PF13412.1 EMD63646.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MutS_V PF00488.16 EMD63647.1 - 2.8e-95 318.1 0.1 4.4e-95 317.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD63647.1 - 1.6e-37 129.2 1.1 1.6e-37 129.2 0.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EMD63647.1 - 1.4e-20 73.7 3.3 6.2e-20 71.6 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EMD63647.1 - 7.1e-18 64.5 3.7 2e-17 63.1 2.5 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EMD63647.1 - 7.2e-18 64.6 0.1 5.4e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain I ABC_tran PF00005.22 EMD63647.1 - 0.034 14.4 0.6 6 7.1 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Peptidase_M16 PF00675.15 EMD63647.1 - 0.053 13.2 0.7 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) Ist1 PF03398.9 EMD63648.1 - 8.4e-64 213.9 6.1 1.1e-63 213.5 4.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway HeLo PF14479.1 EMD63648.1 - 0.62 9.7 6.3 0.073 12.8 1.3 1.6 2 0 0 2 2 2 0 Prion-inhibition and propagation OPT PF03169.10 EMD63649.1 - 0.00029 19.4 0.0 0.00032 19.2 0.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1744 PF08490.7 EMD63649.1 - 0.15 10.5 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) HAD_2 PF13419.1 EMD63650.1 - 1.6e-24 87.1 0.1 3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 EMD63650.1 - 0.0075 16.6 0.1 2.9 8.3 0.0 2.9 3 0 0 3 3 3 2 Prenyltransferase-like Sugar_tr PF00083.19 EMD63651.1 - 1.4e-96 323.8 19.4 1.6e-96 323.6 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD63651.1 - 3.3e-19 68.8 33.2 1.1e-15 57.1 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 EMD63651.1 - 0.47 10.1 4.2 2.6 7.7 0.3 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase NiFeSe_Hases PF00374.14 EMD63652.1 - 0.019 13.7 0.4 0.019 13.7 0.3 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase TFIIA PF03153.8 EMD63652.1 - 2.7 7.8 21.7 3 7.6 15.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CFEM PF05730.6 EMD63653.1 - 0.00013 21.6 3.6 0.00018 21.2 2.5 1.2 1 0 0 1 1 1 1 CFEM domain CYSTM PF12734.2 EMD63654.1 - 0.0033 17.4 1.0 0.0033 17.4 0.7 4.5 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance RRM_1 PF00076.17 EMD63655.1 - 4.7e-10 38.9 0.0 6.4e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63655.1 - 1.6e-07 31.1 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63655.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD63655.1 - 0.0036 17.0 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_4 PF01565.18 EMD63656.1 - 1.8e-26 92.2 0.2 3.8e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD63656.1 - 0.012 15.4 0.1 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like DHHA1 PF02272.14 EMD63656.1 - 0.038 13.6 0.1 0.088 12.5 0.1 1.6 1 0 0 1 1 1 0 DHHA1 domain 7tm_3 PF00003.17 EMD63657.1 - 0.012 14.9 0.2 0.012 14.9 0.1 2.7 1 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4131 PF13567.1 EMD63657.1 - 0.34 10.3 7.1 24 4.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) zf-CCCH_2 PF14608.1 EMD63658.1 - 7.5e-13 47.9 45.6 3.2e-06 26.9 3.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Fork_head_N PF08430.7 EMD63658.1 - 6.9 7.0 31.8 8.2 6.8 15.4 2.6 2 0 0 2 2 2 0 Forkhead N-terminal region NAD_binding_8 PF13450.1 EMD63659.1 - 3.4e-11 42.9 0.7 8.1e-11 41.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMD63659.1 - 2.4e-10 40.0 0.9 5.1e-08 32.4 0.6 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMD63659.1 - 3.3e-07 29.5 0.4 3.8e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD63659.1 - 0.078 13.3 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 EMD63661.1 - 4.6e-53 180.0 0.0 6.3e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63661.1 - 4.5e-27 94.7 0.0 1.4e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD63661.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Spermine_synth PF01564.12 EMD63663.1 - 5.6e-07 28.7 0.0 9.3e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EMD63663.1 - 0.00026 20.9 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2052 PF09747.4 EMD63664.1 - 7.9e-35 120.4 7.4 7.9e-35 120.4 5.2 2.0 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) AA_permease PF00324.16 EMD63666.1 - 2.7e-119 398.6 42.1 3.4e-119 398.3 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD63666.1 - 5.2e-34 117.5 45.0 6.4e-34 117.2 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease CNH PF00780.17 EMD63667.1 - 1e-78 264.5 0.0 1.5e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EMD63667.1 - 8.5e-30 103.9 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EMD63667.1 - 2.5e-13 50.1 0.0 4.7e-12 46.0 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMD63667.1 - 1.3e-05 25.3 0.0 3.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Gly_transf_sug PF04488.10 EMD63668.1 - 6.5e-13 48.9 0.4 1.7e-12 47.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMD63668.1 - 0.0021 17.2 0.2 0.0039 16.3 0.1 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.17 EMD63669.1 - 1.4e-29 102.9 35.0 1.7e-29 102.7 24.2 1.1 1 0 0 1 1 1 1 Acyltransferase family Hydantoinase_B PF02538.9 EMD63670.1 - 6.9e-197 654.8 0.0 9.1e-196 651.1 0.0 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMD63670.1 - 1.2e-94 316.6 0.1 2.8e-94 315.4 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMD63670.1 - 1.5e-58 197.2 2.9 1.1e-57 194.3 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 EMD63671.1 - 0.0059 15.5 0.0 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PapG_C PF03628.8 EMD63671.1 - 0.011 15.3 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 PapG chaperone-binding domain TIM-br_sig_trns PF09370.5 EMD63672.1 - 5.7e-137 455.1 1.1 6.5e-137 454.9 0.8 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EMD63672.1 - 1.1e-05 24.8 0.2 1.5e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase CSTF_C PF14304.1 EMD63672.1 - 0.17 11.1 0.1 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal PcrB PF01884.12 EMD63672.1 - 0.31 10.2 2.7 2.8 7.1 0.1 2.8 2 1 0 3 3 3 0 PcrB family UPF0261 PF06792.6 EMD63673.1 - 2.8e-154 513.4 2.8 3.3e-154 513.2 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Glyco_hydro_76 PF03663.9 EMD63674.1 - 9.1e-104 347.7 10.7 1.2e-103 347.4 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_47 PF01532.15 EMD63674.1 - 0.0078 14.9 0.0 0.43 9.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 FAD_binding_6 PF00970.19 EMD63675.1 - 7e-29 99.8 0.0 1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD63675.1 - 6.1e-28 97.5 0.0 1.2e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMD63675.1 - 2.6e-05 24.1 0.0 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMD63675.1 - 0.00072 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4330 PF14221.1 EMD63675.1 - 0.012 15.4 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) TPR_10 PF13374.1 EMD63676.1 - 1.9e-06 27.6 0.2 2.6e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD63676.1 - 3.9e-06 26.7 0.1 4.5e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD63677.1 - 4.5e-100 327.7 10.1 7.4e-17 61.0 0.0 6.1 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 EMD63677.1 - 2.4e-93 303.7 9.4 7.3e-14 51.1 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMD63677.1 - 6.9e-28 94.2 6.3 0.0098 15.6 0.0 7.3 7 0 0 7 7 6 6 Tetratricopeptide repeat HET PF06985.6 EMD63677.1 - 3e-21 76.0 13.2 2.3e-18 66.6 8.6 4.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_17 PF13431.1 EMD63677.1 - 2.5e-19 67.8 4.7 0.32 11.3 0.0 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_4 PF07721.9 EMD63677.1 - 2.6e-15 55.1 0.4 1.1 9.8 0.0 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD63677.1 - 4.6e-14 51.8 6.5 0.00069 19.2 0.1 5.3 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 EMD63677.1 - 5.8e-14 50.8 15.1 1.8 8.7 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMD63677.1 - 7.3e-14 50.6 9.8 1.5 8.5 0.0 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMD63677.1 - 3.3e-13 49.7 6.2 5.5 7.4 0.0 7.9 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63677.1 - 5.4e-11 42.8 1.2 1 10.1 0.1 7.3 1 1 5 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 EMD63677.1 - 9.9e-11 41.0 0.0 2.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EMD63677.1 - 2.6e-10 39.3 6.3 11 6.0 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD63677.1 - 5.3e-09 36.0 2.8 0.28 11.3 0.0 6.6 2 1 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMD63677.1 - 3.7e-07 30.1 14.4 22 6.0 0.0 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD63677.1 - 6.7e-07 29.3 9.4 13 6.4 0.0 7.7 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_16 PF13191.1 EMD63677.1 - 4.1e-06 26.9 2.9 2e-05 24.6 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMD63677.1 - 4.2e-05 23.7 0.2 0.00018 21.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 EMD63677.1 - 0.025 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EMD63677.1 - 0.033 13.5 0.0 0.15 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain zf-Mss51 PF13824.1 EMD63677.1 - 0.42 10.5 4.9 90 3.0 0.0 5.2 6 0 0 6 6 6 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_11 PF13414.1 EMD63678.1 - 3.8e-44 148.1 23.3 3.4e-12 45.8 0.0 7.5 4 1 4 8 8 8 8 TPR repeat TPR_2 PF07719.12 EMD63678.1 - 3.5e-36 120.1 27.2 3.8e-07 29.5 0.9 10.5 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMD63678.1 - 2.2e-35 118.7 18.9 1.2e-06 27.8 1.1 9.3 10 0 0 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 EMD63678.1 - 6.1e-30 103.2 13.5 2.8e-18 65.8 0.1 5.3 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMD63678.1 - 1.2e-26 90.4 11.8 6.1e-05 22.5 0.6 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD63678.1 - 6.4e-26 90.4 28.6 2.7e-07 31.0 1.8 7.8 5 1 2 8 8 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMD63678.1 - 2.6e-25 88.1 22.8 2.6e-07 30.4 0.0 7.9 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMD63678.1 - 1.2e-23 81.2 12.7 0.0073 16.4 0.0 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMD63678.1 - 8e-20 69.5 19.2 0.0012 19.3 0.0 10.2 6 2 6 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMD63678.1 - 2.7e-19 69.2 13.7 0.00056 20.1 0.1 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD63678.1 - 5.7e-14 50.7 10.7 0.017 14.8 0.2 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMD63678.1 - 8.6e-12 44.7 14.5 0.37 11.3 0.0 9.9 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMD63678.1 - 2.1e-05 24.2 10.9 0.45 10.4 0.0 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.1 EMD63678.1 - 0.00039 20.4 3.5 3 8.0 0.1 4.9 4 2 2 6 6 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD63678.1 - 0.0019 18.0 15.7 0.021 14.7 0.3 6.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMD63678.1 - 0.0021 17.1 12.4 0.0025 16.9 3.2 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 EMD63678.1 - 0.019 13.9 5.3 1 8.2 2.2 3.2 2 1 1 3 3 3 0 FAT domain RPN7 PF10602.4 EMD63678.1 - 0.55 9.5 6.2 18 4.6 0.0 4.0 3 1 1 4 4 4 0 26S proteasome subunit RPN7 Prenyltrans_2 PF13249.1 EMD63678.1 - 0.62 10.4 3.2 2 8.8 0.0 3.1 4 0 0 4 4 3 0 Prenyltransferase-like DUF788 PF05620.6 EMD63679.1 - 4.8e-49 166.4 0.1 5.5e-49 166.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Bot1p PF12298.3 EMD63680.1 - 4.1e-55 186.3 2.0 4.1e-55 186.3 1.4 2.8 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein Pox_Ag35 PF03286.9 EMD63680.1 - 2.3 7.6 13.1 0.59 9.6 0.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3987 PF13148.1 EMD63680.1 - 9.4 4.6 9.9 0.7 8.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RRM_1 PF00076.17 EMD63682.1 - 3.2e-16 58.7 0.0 9.7e-14 50.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63682.1 - 3.2e-10 39.8 0.0 2.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2217 PF10265.4 EMD63683.1 - 0.15 10.7 2.5 0.16 10.6 1.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ebola_NP PF05505.7 EMD63683.1 - 0.21 9.6 3.0 0.23 9.5 2.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein RR_TM4-6 PF06459.7 EMD63683.1 - 0.55 10.0 4.3 0.64 9.8 3.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2370 PF10176.4 EMD63683.1 - 1.4 8.1 4.7 1.4 8.2 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) Sugar_tr PF00083.19 EMD63684.1 - 2.5e-11 42.8 1.7 2.7e-11 42.7 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF779 PF05610.6 EMD63684.1 - 0.071 13.1 0.2 0.099 12.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF779) Nitroreductase PF00881.19 EMD63685.1 - 4.6e-12 46.0 0.0 5.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family zf-C3H1 PF10650.4 EMD63687.1 - 7.5e-11 41.3 1.8 1.1e-10 40.7 1.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain YebO PF13974.1 EMD63687.1 - 0.11 12.3 1.2 0.58 9.9 0.8 2.3 1 0 0 1 1 1 0 YebO-like protein Sod_Cu PF00080.15 EMD63688.1 - 1.8e-45 154.5 7.3 2.1e-45 154.3 5.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 EMD63689.1 - 1.2e-94 316.6 2.7 1.4e-94 316.5 1.9 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EMD63689.1 - 0.0054 16.0 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus adh_short PF00106.20 EMD63690.1 - 4.7e-16 59.1 0.0 8.8e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD63690.1 - 9.2e-06 25.5 0.0 0.009 15.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD63690.1 - 0.00035 20.2 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 2 KR domain NMT1_2 PF13379.1 EMD63690.1 - 0.029 13.7 0.1 0.062 12.6 0.1 1.5 1 1 0 1 1 1 0 NMT1-like family Acyltransferase PF01553.16 EMD63691.1 - 5.7e-33 113.1 0.0 8.4e-33 112.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Voltage_CLC PF00654.15 EMD63692.1 - 0.00086 18.4 1.9 0.0011 18.0 1.3 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel TRP PF06011.7 EMD63692.1 - 0.0045 15.6 2.1 0.0063 15.1 0.7 1.6 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF2232 PF09991.4 EMD63692.1 - 0.044 12.7 4.0 0.072 12.0 1.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2232) Glucos_trans_II PF14264.1 EMD63692.1 - 0.045 12.7 0.2 0.045 12.7 0.2 2.2 3 0 0 3 3 3 0 Glucosyl transferase GtrII DUF2116 PF09889.4 EMD63692.1 - 0.21 11.3 1.0 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Tetraspannin PF00335.15 EMD63692.1 - 0.9 8.7 9.3 0.38 9.9 4.1 2.0 1 1 1 2 2 2 0 Tetraspanin family MARVEL PF01284.18 EMD63692.1 - 2.7 7.8 11.4 8.9 6.1 5.6 2.7 2 1 0 2 2 2 0 Membrane-associating domain Tuberin PF03542.11 EMD63693.1 - 0.061 12.3 0.1 0.061 12.3 0.0 1.0 1 0 0 1 1 1 0 Tuberin Glyco_hydro_16 PF00722.16 EMD63694.1 - 1.2e-37 128.9 3.2 2e-37 128.3 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Bacteriocin_IIc PF10439.4 EMD63694.1 - 1.3 9.2 7.4 4.8 7.3 5.1 2.0 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RIO1 PF01163.17 EMD63695.1 - 5.5e-68 228.0 0.4 1.1e-67 227.1 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Zip PF02535.17 EMD63695.1 - 9.9 5.0 6.9 20 4.0 1.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter NAD_binding_10 PF13460.1 EMD63696.1 - 1.3e-12 48.1 0.0 6.4e-11 42.5 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD63696.1 - 1.9e-08 34.0 0.0 1.2e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD63696.1 - 7.8e-07 28.0 0.0 4.7e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD63696.1 - 0.0031 17.4 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMD63696.1 - 0.035 13.0 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMD63696.1 - 0.049 12.5 1.2 6.3 5.6 0.0 3.3 2 2 1 3 3 3 0 Male sterility protein PLAC9 PF15205.1 EMD63697.1 - 0.047 13.9 0.1 0.059 13.6 0.1 1.2 1 0 0 1 1 1 0 Placenta-specific protein 9 FPN1 PF06963.7 EMD63697.1 - 0.055 11.8 0.0 0.064 11.6 0.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Vps54 PF07928.7 EMD63697.1 - 0.07 13.2 0.0 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Vps54-like protein HTH_11 PF08279.7 EMD63697.1 - 0.11 12.0 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain WD40 PF00400.27 EMD63698.1 - 1e-43 145.7 8.7 1.8e-12 46.6 0.8 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EMD63698.1 - 1.4e-08 33.8 0.0 1.3 8.4 0.0 5.0 5 0 0 5 5 5 4 Proteasome subunit A N-terminal signature NACHT PF05729.7 EMD63698.1 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD63698.1 - 5.6e-07 29.7 2.1 5e-06 26.6 0.6 2.8 2 1 0 2 2 2 1 AAA ATPase domain eIF2A PF08662.6 EMD63698.1 - 1.4e-05 24.9 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMD63698.1 - 0.00012 20.3 1.6 0.34 8.9 0.0 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 AAA_22 PF13401.1 EMD63698.1 - 0.0017 18.5 0.0 0.0052 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EMD63698.1 - 0.0026 17.4 0.1 0.0071 16.0 0.0 1.8 2 0 0 2 2 1 1 Adenylylsulphate kinase Stimulus_sens_1 PF13756.1 EMD63698.1 - 0.003 17.9 0.0 5.6 7.4 0.0 3.7 3 0 0 3 3 3 1 Stimulus-sensing domain Nucleoporin_N PF08801.6 EMD63698.1 - 0.0062 15.3 0.0 4.4 5.9 0.0 3.0 1 1 1 2 2 2 2 Nup133 N terminal like KAP_NTPase PF07693.9 EMD63698.1 - 0.0063 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain TruB_C PF09142.6 EMD63698.1 - 0.025 14.2 0.3 31 4.2 0.0 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal AAA_17 PF13207.1 EMD63698.1 - 0.025 15.3 0.1 0.084 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD63698.1 - 0.025 14.2 0.0 0.1 12.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EMD63698.1 - 0.066 13.4 0.1 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMD63698.1 - 0.11 12.4 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMD63698.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IKI3 PF04762.7 EMD63698.1 - 0.16 9.7 0.1 0.58 7.8 0.0 1.7 1 1 0 1 1 1 0 IKI3 family AAA_30 PF13604.1 EMD63698.1 - 0.19 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 EMD63699.1 - 9.7e-18 63.9 0.0 3.7e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Mitoc_L55 PF09776.4 EMD63699.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 HAUS4 PF14735.1 EMD63699.1 - 0.1 11.8 0.0 9.3 5.4 0.0 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 AMP-binding PF00501.23 EMD63700.1 - 0 1146.0 0.2 2.4e-87 293.0 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EMD63700.1 - 6.8e-187 619.4 0.3 7.4e-57 192.4 0.2 4.6 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EMD63700.1 - 4e-54 180.7 8.2 7.4e-13 48.5 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EMD63700.1 - 4.8e-41 138.9 3.9 2.4e-19 69.4 0.1 4.0 3 0 0 3 3 3 2 HxxPF-repeated domain AMP-binding_C PF13193.1 EMD63700.1 - 1.9e-29 102.4 10.0 5.1e-05 24.1 0.0 7.4 6 0 0 6 6 6 6 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 EMD63700.1 - 1.6e-14 53.7 0.0 8.1e-07 28.7 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 EMD63700.1 - 1.2e-12 48.0 0.0 1.9e-05 24.9 0.0 3.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EMD63700.1 - 6.4e-12 46.0 0.0 5.2e-06 27.0 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EMD63700.1 - 2.8e-11 43.4 0.0 0.00075 19.2 0.0 3.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 EMD63700.1 - 5.6e-10 39.5 0.0 0.0007 20.0 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EMD63700.1 - 4.8e-09 36.2 0.0 0.0014 18.6 0.0 3.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EMD63700.1 - 0.00016 21.0 0.0 0.67 9.3 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase small domain NodS PF05401.6 EMD63700.1 - 0.0074 15.6 0.0 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EMD63700.1 - 0.0083 15.5 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Putative methyltransferase Viral_P18 PF04521.8 EMD63700.1 - 0.39 10.1 0.2 18 4.7 0.0 2.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein YEATS PF03366.11 EMD63701.1 - 3.9e-28 96.9 0.1 6.8e-28 96.2 0.1 1.4 1 0 0 1 1 1 1 YEATS family Ribosomal_L29 PF00831.18 EMD63701.1 - 1.9 8.2 5.9 0.77 9.4 0.8 2.2 1 1 1 2 2 2 0 Ribosomal L29 protein IncA PF04156.9 EMD63701.1 - 2.9 7.4 6.9 0.33 10.5 1.8 1.5 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 EMD63701.1 - 6.4 6.3 7.2 14 5.2 5.0 1.5 1 0 0 1 1 1 0 Septum formation initiator GST_C PF00043.20 EMD63702.1 - 7.7e-14 51.4 0.5 5e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD63702.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD63702.1 - 8.5e-08 32.3 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD63702.1 - 1.3e-07 31.9 0.1 3.1e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD63702.1 - 3.7e-06 26.8 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD63702.1 - 5.1e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MARVEL PF01284.18 EMD63703.1 - 4.9e-07 29.6 9.2 8e-07 28.9 6.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain FA_desaturase PF00487.19 EMD63703.1 - 8.5 5.7 9.6 5.7 6.2 5.0 1.7 1 1 1 2 2 2 0 Fatty acid desaturase Ras PF00071.17 EMD63704.1 - 6.4e-41 139.4 0.0 1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF2823 PF11034.3 EMD63704.1 - 5.9e-18 64.7 6.7 9.8e-18 64.0 4.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Miro PF08477.8 EMD63704.1 - 1e-13 51.8 0.0 2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMD63704.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMD63704.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF4491 PF14898.1 EMD63704.1 - 0.079 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) HPIP PF15226.1 EMD63705.1 - 0.48 10.4 6.0 2.1 8.4 1.0 2.2 1 1 1 2 2 2 0 HCF-1 beta-propeller-interacting protein family DUF1620 PF07774.8 EMD63706.1 - 1.8e-72 243.1 0.0 4.1e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EMD63706.1 - 3.7e-22 78.9 11.9 5.4e-19 68.5 1.2 4.3 2 2 2 4 4 4 2 PQQ-like domain PQQ PF01011.16 EMD63706.1 - 4.5e-10 38.5 4.6 0.0088 15.5 0.0 5.2 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 EMD63706.1 - 0.022 14.9 5.0 10 6.5 0.0 6.0 5 2 1 6 6 6 0 PQQ-like domain Peptidase_S7 PF00949.16 EMD63706.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Pigment_DH PF06324.6 EMD63706.1 - 1.4 8.2 3.8 3.5 7.0 0.4 2.5 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) p450 PF00067.17 EMD63707.1 - 2.2e-51 174.8 0.0 4e-51 173.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EMD63708.1 - 1.7e-22 79.8 0.0 2.5e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD63708.1 - 9.1e-09 35.0 0.0 2.1e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD63708.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD63708.1 - 3.2e-08 33.9 0.0 2e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD63708.1 - 4.5e-08 33.6 0.0 8.1e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD63708.1 - 1.4e-06 28.5 0.0 3.6e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMD63708.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 EMD63708.1 - 0.017 14.7 0.0 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EMD63708.1 - 0.023 14.7 0.0 0.2 11.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EMD63708.1 - 0.036 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EMD63708.1 - 0.048 13.6 0.1 0.077 12.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EMD63708.1 - 0.078 12.0 0.0 0.44 9.6 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EMD63708.1 - 0.14 11.1 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EMD63708.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain APG17 PF04108.7 EMD63709.1 - 1.1e-80 271.5 1.7 1.8e-80 270.8 1.2 1.3 1 1 0 1 1 1 1 Autophagy protein Apg17 Baculo_PEP_C PF04513.7 EMD63709.1 - 0.00043 20.1 7.8 1.7 8.4 0.6 3.5 2 1 0 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 EMD63709.1 - 0.0064 15.8 2.8 0.23 10.7 0.0 3.4 3 1 1 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) WEMBL PF05701.6 EMD63709.1 - 0.029 12.8 10.7 0.008 14.6 4.6 1.9 2 0 0 2 2 2 0 Weak chloroplast movement under blue light MCPsignal PF00015.16 EMD63709.1 - 0.03 13.8 0.5 0.03 13.8 0.3 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 EMD63709.1 - 0.071 13.2 10.3 2.4 8.3 0.4 4.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EMD63709.1 - 0.44 10.9 8.6 3.9 7.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EMD63709.1 - 0.51 8.1 2.6 10 3.7 0.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EMD63709.1 - 0.74 10.1 6.2 8.2 6.7 0.5 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EMD63709.1 - 3.6 6.7 13.1 4.4 6.4 0.1 3.3 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding SseC PF04888.7 EMD63709.1 - 7.8 5.7 7.4 0.53 9.5 0.2 2.3 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family IncA PF04156.9 EMD63709.1 - 8.1 5.9 15.3 45 3.5 0.0 3.7 2 2 0 2 2 1 0 IncA protein WD40 PF00400.27 EMD63710.1 - 4.1e-59 194.4 24.5 1.4e-09 37.4 0.0 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EMD63710.1 - 2.3e-12 46.4 0.1 4.9e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD63710.1 - 4e-10 39.0 0.4 4e-09 35.9 0.0 2.5 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 EMD63710.1 - 1.2e-09 36.8 6.8 0.0043 15.2 0.2 4.5 3 1 2 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMD63710.1 - 9e-05 22.2 0.0 2.4 7.9 0.0 4.0 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Ins_P5_2-kin PF06090.7 EMD63711.1 - 7.9e-41 140.1 0.0 3.2e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF952 PF06108.7 EMD63712.1 - 1.7e-23 82.3 0.0 2.2e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Fungal_trans PF04082.13 EMD63713.1 - 2.3e-10 39.8 0.2 7e-10 38.2 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63713.1 - 3.8e-06 26.6 8.3 6.9e-06 25.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain L31 PF09784.4 EMD63714.1 - 5e-48 161.4 4.1 5.5e-48 161.2 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.8 EMD63715.1 - 3.1e-32 111.2 0.0 3.6e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CPSase_L_D2 PF02786.12 EMD63720.1 - 4.7e-73 244.9 0.0 6.9e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMD63720.1 - 2.3e-35 120.8 0.0 8.1e-35 119.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EMD63720.1 - 3.5e-34 117.2 0.0 7.4e-34 116.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EMD63720.1 - 2.6e-18 66.3 0.0 8.9e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EMD63720.1 - 2.2e-16 59.2 1.0 6.1e-16 57.8 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EMD63720.1 - 7.4e-12 44.6 0.0 1.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMD63720.1 - 2e-10 40.4 0.0 3.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMD63720.1 - 2e-08 33.8 0.0 3.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMD63720.1 - 5.3e-06 26.0 0.0 0.00011 21.8 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EMD63720.1 - 6.4e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EMD63720.1 - 0.00037 19.8 0.8 0.62 9.3 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 EMD63720.1 - 0.0014 18.1 0.0 0.0052 16.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EMD63720.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EMD63720.1 - 0.006 16.2 0.2 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 EMD63720.1 - 0.044 14.1 0.0 12 6.3 0.0 2.9 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 EMD63720.1 - 0.099 11.7 0.1 0.27 10.3 0.1 1.7 1 1 0 1 1 1 0 HlyD family secretion protein Herpes_DNAp_acc PF04929.7 EMD63721.1 - 0.046 12.6 7.5 0.092 11.7 5.2 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Snf7 PF03357.16 EMD63721.1 - 0.63 9.4 4.3 1.2 8.4 3.0 1.5 1 0 0 1 1 1 0 Snf7 Lin-8 PF03353.10 EMD63721.1 - 1.8 7.7 6.6 4.3 6.5 4.6 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RINGv PF12906.2 EMD63722.1 - 8.3e-16 57.7 9.3 1.4e-15 56.9 6.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EMD63722.1 - 0.04 13.7 2.7 0.089 12.6 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMD63722.1 - 0.068 13.0 8.4 0.12 12.2 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain E1-E2_ATPase PF00122.15 EMD63722.1 - 4.2 6.3 7.0 0.22 10.5 0.4 2.2 2 0 0 2 2 2 0 E1-E2 ATPase zf-RING_4 PF14570.1 EMD63722.1 - 7.9 6.1 6.1 16 5.1 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_tran_WecB PF03808.8 EMD63723.1 - 0.041 13.2 1.7 1.5 8.2 0.1 3.0 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Baculo_gp41 PF04700.7 EMD63723.1 - 0.045 13.1 6.3 0.14 11.5 0.3 4.0 4 0 0 4 4 4 0 Structural glycoprotein p40/gp41 conserved region CAF-1_p150 PF11600.3 EMD63724.1 - 0.0019 17.6 30.4 0.0019 17.6 21.1 2.9 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4603 PF15376.1 EMD63724.1 - 0.26 8.4 20.2 0.43 7.7 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ycf1 PF05758.7 EMD63724.1 - 2.1 5.9 7.7 2.7 5.6 5.3 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 EMD63724.1 - 2.5 6.2 16.6 3.3 5.8 11.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CcoS PF03597.10 EMD63724.1 - 9 5.8 5.9 16 5.0 4.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type MFS_1 PF07690.11 EMD63725.1 - 2.7e-35 121.7 52.7 2.7e-35 121.7 36.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M14 PF00246.19 EMD63726.1 - 1.6e-75 254.3 0.1 2e-75 253.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMD63726.1 - 1.8e-07 30.7 0.1 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_transf_20 PF00982.16 EMD63728.1 - 3.7e-201 668.6 0.0 4.3e-201 668.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EMD63728.1 - 0.024 14.1 0.3 0.048 13.1 0.1 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EMD63728.1 - 0.099 12.0 0.3 3.9 6.8 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferases group 1 MIP-T3 PF10243.4 EMD63729.1 - 6.1 5.1 41.3 9 4.6 28.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SDF PF00375.13 EMD63730.1 - 1.9e-89 300.1 40.9 2.2e-89 299.9 28.4 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 EMD63730.1 - 3.1 7.5 11.6 0.034 13.7 0.9 3.1 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4066 PF13278.1 EMD63731.1 - 9.6e-20 70.4 0.1 1.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD63731.1 - 2e-09 37.0 0.2 4.8e-09 35.8 0.2 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.20 EMD63732.1 - 3.9e-33 114.7 0.0 4.7e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63732.1 - 6.2e-14 51.6 0.0 1.5e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_34 PF05637.7 EMD63733.1 - 7.1e-05 22.4 0.4 0.015 14.7 0.3 2.2 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family HAD PF12710.2 EMD63734.1 - 4.3e-06 27.0 0.0 5.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMD63734.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4238 PF14022.1 EMD63735.1 - 2e-13 50.2 0.0 1.7e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4238) MR_MLE_C PF13378.1 EMD63736.1 - 4.6e-34 116.7 0.0 8.7e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EMD63736.1 - 4.8e-17 62.0 0.0 9.5e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EMD63736.1 - 8.5e-09 35.8 0.0 3.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DHDPS PF00701.17 EMD63737.1 - 5.4e-27 94.1 0.0 7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.7 EMD63737.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MFS_1 PF07690.11 EMD63738.1 - 1.7e-31 109.2 37.1 1.7e-31 109.2 25.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily IMS PF00817.15 EMD63739.1 - 1.9e-40 138.1 0.0 4.1e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family DUF4414 PF14377.1 EMD63739.1 - 1.2e-17 63.8 8.6 9.6e-08 31.9 1.3 5.2 4 1 0 4 4 4 2 Domain of unknown function (DUF4414) IMS_C PF11799.3 EMD63739.1 - 5.1e-16 58.7 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EMD63739.1 - 3.9e-08 33.3 0.0 9.6e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD63739.1 - 8.3e-07 28.7 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EMD63739.1 - 0.0064 16.4 2.2 0.02 14.9 0.2 2.8 3 0 0 3 3 3 1 IMS family HHH motif HHH_5 PF14520.1 EMD63739.1 - 0.087 13.0 0.1 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain MgtE_N PF03448.12 EMD63739.1 - 0.14 12.4 1.5 30 5.0 0.0 3.6 3 0 0 3 3 3 0 MgtE intracellular N domain FKBP_C PF00254.23 EMD63740.1 - 1.4e-31 108.3 0.0 3.7e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Trypan_PARP PF05887.6 EMD63740.1 - 0.0058 16.4 7.0 0.0058 16.4 4.9 4.4 3 2 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) ODC_AZ PF02100.12 EMD63741.1 - 3.6e-24 84.3 0.0 4.5e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1227 PF06777.6 EMD63742.1 - 2.8e-59 199.0 0.2 7.2e-59 197.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EMD63742.1 - 4.5e-51 172.6 0.2 7.2e-51 172.0 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EMD63742.1 - 1.7e-44 151.6 0.0 4.5e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EMD63742.1 - 0.00013 21.5 0.0 0.021 14.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMD63742.1 - 0.00016 20.5 0.0 0.00057 18.7 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMD63742.1 - 0.014 15.1 0.1 0.073 12.8 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMD63742.1 - 0.02 15.0 0.3 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EMD63742.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 EMD63743.1 - 1.2e-06 28.2 4.9 2.3e-06 27.2 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD63743.1 - 1.1e-05 25.4 0.7 2.3e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EMD63743.1 - 1.6e-05 24.7 2.7 9.4e-05 22.2 2.2 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EMD63743.1 - 0.0012 18.6 1.4 0.0029 17.4 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMD63743.1 - 0.011 15.3 5.0 0.024 14.3 3.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) XPC-binding PF09280.6 EMD63743.1 - 0.054 12.9 0.5 3.5 7.1 0.1 3.0 2 0 0 2 2 2 0 XPC-binding domain RINGv PF12906.2 EMD63743.1 - 0.055 13.5 3.8 0.12 12.4 2.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EMD63743.1 - 0.067 13.2 6.8 0.13 12.3 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EMD63743.1 - 0.22 11.3 3.9 0.44 10.3 2.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 EMD63743.1 - 0.56 9.9 3.0 0.95 9.1 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMD63743.1 - 6.1 6.6 4.8 12 5.7 3.4 1.5 1 0 0 1 1 1 0 PHD-finger DSBA PF01323.15 EMD63744.1 - 1.3e-56 191.1 0.0 1.8e-32 112.4 0.0 3.1 3 0 0 3 3 3 3 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EMD63744.1 - 0.1 12.5 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Yippee-Mis18 PF03226.9 EMD63745.1 - 1.3e-14 54.0 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EMD63745.1 - 0.0035 17.2 0.1 0.0049 16.7 0.1 1.4 1 1 0 1 1 1 1 C-terminal domain of RIG-I FAM72 PF14976.1 EMD63745.1 - 0.039 13.7 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 FAM72 protein Pkinase PF00069.20 EMD63747.1 - 3.1e-49 167.4 0.1 2.9e-26 92.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63747.1 - 2.8e-22 79.0 0.1 3.6e-14 52.4 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMD63747.1 - 0.0013 18.5 0.9 0.003 17.3 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMD63747.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RTA1 PF04479.8 EMD63748.1 - 2.2e-39 135.2 1.1 3.2e-39 134.7 0.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 EMD63748.1 - 0.016 14.4 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF4328 PF14219.1 EMD63748.1 - 0.057 12.7 2.4 0.058 12.6 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) p450 PF00067.17 EMD63750.1 - 1.9e-40 138.7 0.0 2.7e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF77 PF01910.12 EMD63751.1 - 4.6e-32 109.5 0.0 5.5e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EMD63751.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 YKOF-related Family DUF1335 PF07056.6 EMD63751.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1335) Med2 PF11214.3 EMD63751.1 - 0.069 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF2404 PF10296.4 EMD63752.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) X PF00739.14 EMD63752.1 - 0.089 12.7 0.3 1.5 8.7 0.4 2.5 2 0 0 2 2 2 0 Trans-activation protein X DUF3635 PF12330.3 EMD63753.1 - 3.5e-11 43.0 0.8 5.8e-07 29.5 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3635) Response_reg PF00072.19 EMD63754.1 - 4.7e-20 71.6 0.0 3.1e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain APH PF01636.18 EMD63757.1 - 1.7e-06 27.9 0.3 3e-06 27.1 0.1 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD63757.1 - 0.047 12.8 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EMD63757.1 - 0.07 11.7 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Rot1 PF10681.4 EMD63757.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal Pkinase PF00069.20 EMD63758.1 - 6.8e-66 222.0 0.0 8.7e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63758.1 - 5.4e-34 117.4 0.0 7.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD63758.1 - 0.00033 20.4 0.1 0.0081 15.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD63758.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EMD63758.1 - 0.055 12.3 0.0 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 vMSA PF00695.14 EMD63758.1 - 0.34 10.0 0.9 0.52 9.4 0.6 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ATP-synt_C PF00137.16 EMD63759.1 - 2.7e-27 94.4 32.2 6.7e-16 57.9 8.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EMD63760.1 - 5.3e-82 275.3 0.0 6.4e-81 271.7 0.0 2.1 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EMD63760.1 - 3.2e-48 163.0 0.1 3.2e-48 163.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 EMD63760.1 - 7.5e-39 133.4 0.4 1.4e-38 132.6 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EMD63760.1 - 3.9e-13 48.9 0.0 7.9e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EthD PF07110.6 EMD63761.1 - 3.3e-06 27.9 0.1 0.04 14.8 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 EMD63761.1 - 0.0076 16.4 0.1 2.6 8.3 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4286) AHS2 PF02626.10 EMD63762.1 - 2.7e-78 262.9 0.0 4e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EMD63762.1 - 9.4e-55 185.1 0.0 2.2e-54 183.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMD63762.1 - 3.9e-39 133.1 0.1 1.2e-38 131.5 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 EMD63762.1 - 1.4e-35 122.6 0.0 2.5e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 EMD63762.1 - 7.8e-30 103.0 0.0 1.5e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EMD63762.1 - 1.1e-12 48.0 0.0 2.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD63762.1 - 2.9e-09 36.1 0.0 4.8e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EMD63762.1 - 5.5e-08 32.3 3.9 2.1e-07 30.4 2.7 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EMD63762.1 - 3.5e-06 26.5 0.0 6.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EMD63762.1 - 0.0011 18.6 1.3 0.33 10.6 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EMD63762.1 - 0.0014 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMD63762.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EMD63762.1 - 0.041 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LamB_YcsF PF03746.11 EMD63763.1 - 1.9e-70 236.7 0.0 2.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF4224 PF13986.1 EMD63763.1 - 0.041 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Pkinase PF00069.20 EMD63764.1 - 3.1e-49 167.4 0.0 4.1e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63764.1 - 6.8e-25 87.6 0.0 1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD63764.1 - 0.015 14.2 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like NPV_P10 PF05531.7 EMD63765.1 - 0.049 13.8 0.5 0.65 10.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ISG65-75 PF11727.3 EMD63765.1 - 0.17 10.9 2.9 0.34 9.9 2.0 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein AAA_13 PF13166.1 EMD63765.1 - 0.81 8.0 8.9 0.27 9.6 1.5 2.1 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 EMD63766.1 - 1.9e-52 176.8 0.0 2.3e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD63766.1 - 8.8e-16 58.4 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD63766.1 - 1.3e-06 27.8 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_clus PF00172.13 EMD63767.1 - 4.6e-14 52.0 28.4 8e-08 32.0 8.2 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EMD63768.1 - 1.8e-83 279.9 0.1 3.2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD63768.1 - 8.1e-59 198.8 1.5 1.1e-58 198.4 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain GATase PF00117.23 EMD63768.1 - 5.3e-44 149.9 0.0 8.7e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EMD63768.1 - 6.7e-44 148.5 0.0 1.3e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Fn3-like PF14310.1 EMD63768.1 - 6.3e-24 83.7 0.0 1.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_C26 PF07722.8 EMD63768.1 - 0.0039 16.6 0.4 0.041 13.3 0.2 2.6 2 1 0 2 2 2 1 Peptidase C26 3-alpha PF03475.9 EMD63769.1 - 0.1 12.3 2.5 2.9 7.7 0.1 2.7 2 0 0 2 2 2 0 3-alpha domain Tmemb_170 PF10190.4 EMD63772.1 - 0.0027 17.7 3.8 0.0036 17.3 2.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 N_methyl_3 PF13633.1 EMD63772.1 - 0.31 11.0 0.2 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site NUDIX PF00293.23 EMD63774.1 - 9.3e-05 22.0 0.0 0.0002 21.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.13 EMD63775.1 - 4.2e-07 29.0 0.4 8.3e-07 28.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63775.1 - 1.9e-05 24.4 11.6 4.4e-05 23.3 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD63776.1 - 1.2e-19 70.1 0.4 2.3e-19 69.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63776.1 - 3.1e-10 39.7 4.8 7.1e-10 38.6 3.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inhibitor_I24 PF10465.4 EMD63776.1 - 0.093 12.4 0.1 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 PinA peptidase inhibitor DUF904 PF06005.7 EMD63776.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AAT PF03417.11 EMD63777.1 - 8.3e-31 107.1 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EMD63777.1 - 0.0026 18.0 0.0 0.0074 16.6 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Polysacc_deac_1 PF01522.16 EMD63778.1 - 7.3e-26 90.2 0.0 1.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EMD63778.1 - 2.8e-09 36.7 0.1 4.1e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 EMD63778.1 - 3.6e-06 26.1 0.1 6.1e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.4 EMD63778.1 - 0.0048 15.0 0.0 0.0073 14.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2194) AAA_35 PF14516.1 EMD63778.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Toxin_29 PF08116.6 EMD63779.1 - 1.3 8.8 6.3 0.44 10.3 2.1 1.9 2 0 0 2 2 2 0 PhTx neurotoxin family VESA1_N PF12785.2 EMD63779.1 - 2.8 6.8 6.3 4.1 6.2 4.4 1.4 1 1 0 1 1 1 0 Variant erythrocyte surface antigen-1 Acetyltransf_1 PF00583.19 EMD63780.1 - 3.1e-05 23.9 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD63780.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.15 EMD63781.1 - 2.8e-28 99.0 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PAP_assoc PF03828.14 EMD63783.1 - 9.8e-17 60.6 0.0 2.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMD63783.1 - 0.00016 21.9 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetate_kinase PF00871.12 EMD63784.1 - 3.1e-99 332.1 0.0 3.7e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Ank_2 PF12796.2 EMD63785.1 - 6.4e-54 180.2 6.8 1e-14 54.6 0.0 8.0 7 2 1 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMD63785.1 - 7.2e-39 129.6 14.9 9.1e-06 25.2 0.0 13.7 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.1 EMD63785.1 - 2.3e-28 98.0 7.6 2.6e-07 30.9 0.0 11.0 7 4 4 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD63785.1 - 2.6e-28 95.2 13.1 0.00019 21.3 0.0 13.1 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.1 EMD63785.1 - 1.3e-23 82.4 9.3 0.013 15.7 0.0 11.8 8 6 3 12 12 12 5 Ankyrin repeats (many copies) Clr5 PF14420.1 EMD63785.1 - 5.4e-13 48.6 0.2 1.2e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Clr5 domain DUF3447 PF11929.3 EMD63785.1 - 0.00012 21.8 0.2 0.026 14.3 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) Pyr_redox PF00070.22 EMD63786.1 - 8.6e-13 48.5 0.1 6.9e-12 45.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD63786.1 - 1.1e-11 44.9 0.0 1.9e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD63786.1 - 1.7e-07 31.5 0.6 0.0031 17.6 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD63786.1 - 4e-05 22.6 0.1 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMD63786.1 - 0.0024 16.8 0.2 0.054 12.3 0.0 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD63786.1 - 0.0046 16.7 0.6 1.9 8.2 0.0 3.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD63786.1 - 0.062 11.7 2.3 0.61 8.4 0.0 2.8 3 1 0 3 3 3 0 HI0933-like protein RAI16-like PF10257.4 EMD63787.1 - 2.9e-82 276.4 0.6 4.7e-82 275.7 0.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DinB PF05163.7 EMD63787.1 - 0.026 14.2 0.4 5.2 6.7 0.0 3.0 2 0 0 2 2 2 0 DinB family Mito_carr PF00153.22 EMD63788.1 - 7.8e-71 233.8 2.8 2.6e-23 81.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EMD63789.1 - 2.7e-24 85.4 0.0 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4415 PF14384.1 EMD63789.1 - 0.74 10.0 2.9 0.34 11.1 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4415) U3_snoRNA_assoc PF08297.6 EMD63790.1 - 1.5e-19 70.0 5.8 1.5e-19 70.0 4.0 4.1 4 3 0 4 4 4 1 U3 snoRNA associated AT_hook PF02178.14 EMD63790.1 - 0.14 11.8 6.7 1.1 9.1 4.6 2.7 1 0 0 1 1 1 0 AT hook motif TPR_8 PF13181.1 EMD63791.1 - 1.3e-05 24.6 0.1 0.021 14.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD63791.1 - 0.00037 20.3 1.8 0.04 13.8 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD63791.1 - 0.0014 18.3 0.0 1.8 8.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD63791.1 - 0.01 15.5 0.1 0.084 12.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMD63791.1 - 0.018 15.0 2.1 0.67 9.8 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD63791.1 - 0.049 14.1 2.4 0.28 11.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD63791.1 - 0.12 12.6 0.1 26 5.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD63791.1 - 0.13 12.9 2.0 1.7 9.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Isochorismatase PF00857.15 EMD63792.1 - 7.6e-28 97.5 0.0 1e-18 67.8 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Ldh_2 PF02615.9 EMD63792.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase ETF PF01012.16 EMD63793.1 - 1.3e-33 116.0 2.6 1.7e-33 115.6 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Nucleoside_tran PF01733.13 EMD63794.1 - 5.2e-43 147.3 12.1 1.8e-41 142.2 8.4 2.2 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 EMD63794.1 - 7.6e-08 31.4 37.9 0.00017 20.4 18.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1762 PF08574.5 EMD63795.1 - 2.9e-12 46.8 11.4 2.9e-12 46.8 7.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) ubiquitin PF00240.18 EMD63797.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family PB1 PF00564.19 EMD63797.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PB1 domain HTH_psq PF05225.11 EMD63798.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Ank_2 PF12796.2 EMD63801.1 - 2.6e-27 94.9 4.0 1.1e-14 54.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD63801.1 - 2.2e-23 80.7 6.4 2.1e-06 27.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMD63801.1 - 3e-21 75.3 4.7 2.4e-06 27.9 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD63801.1 - 5.4e-14 50.9 1.3 0.0048 17.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMD63801.1 - 1.1e-11 44.5 11.0 1.1e-05 25.5 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PPR_3 PF13812.1 EMD63801.1 - 0.00051 20.1 0.5 0.74 10.2 0.0 2.7 3 0 0 3 3 3 2 Pentatricopeptide repeat domain CW_binding_2 PF04122.7 EMD63801.1 - 0.074 13.2 0.4 10 6.3 0.0 2.7 1 1 2 3 3 3 0 Putative cell wall binding repeat 2 DUF2521 PF10730.4 EMD63801.1 - 0.14 11.9 0.2 23 4.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2521) DUF1771 PF08590.5 EMD63801.1 - 1.6 8.8 7.2 2.3 8.3 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1771) ubiquitin PF00240.18 EMD63802.1 - 2e-24 84.7 0.0 2.3e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMD63802.1 - 5.6e-17 61.1 0.1 6.2e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMD63802.1 - 0.00012 22.2 0.0 0.00033 20.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMD63802.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CTDII PF01556.13 EMD63802.1 - 0.085 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain Zein PF01559.11 EMD63803.1 - 0.019 14.2 0.4 0.023 13.9 0.3 1.3 1 0 0 1 1 1 0 Zein seed storage protein DUF2722 PF10846.3 EMD63804.1 - 6e-06 25.5 0.5 6e-06 25.5 0.3 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF2722) Adeno_PX PF05829.7 EMD63804.1 - 0.0014 18.0 0.1 0.0034 16.8 0.1 1.6 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) RabGAP-TBC PF00566.13 EMD63805.1 - 2.5e-32 112.0 2.8 2.8e-32 111.9 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NTPase_P4 PF11602.3 EMD63806.1 - 0.075 12.0 0.0 0.081 11.9 0.0 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF3441 PF11923.3 EMD63807.1 - 5.1e-37 125.9 0.1 5.1e-37 125.9 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EMD63807.1 - 2.2e-32 112.1 11.2 2.2e-32 112.1 7.8 2.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EMD63807.1 - 7.9e-18 64.1 0.0 2.5e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 EMD63808.1 - 6.2e-14 51.9 0.5 1.1e-13 51.0 0.3 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans PF04082.13 EMD63810.1 - 1.6e-29 102.5 0.5 3e-29 101.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 EMD63811.1 - 4.2e-64 215.7 3.1 4.2e-64 215.7 2.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD63811.1 - 5.3e-30 104.2 11.9 5.3e-30 104.2 8.2 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD63811.1 - 3.1e-26 93.1 0.0 2.2e-24 87.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD63811.1 - 8e-16 57.7 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMD63811.1 - 3.9e-15 55.0 2.6 5.1e-15 54.6 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMD63811.1 - 4.4e-14 53.0 0.0 1.3e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD63811.1 - 0.00064 19.3 0.3 0.0044 16.6 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4089 PF13318.1 EMD63811.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) DUF3671 PF12420.3 EMD63811.1 - 3.1 7.8 6.2 6.7 6.7 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function zf-RING_2 PF13639.1 EMD63812.1 - 8.7e-10 38.2 4.0 2.3e-08 33.7 1.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMD63812.1 - 7.1e-07 29.2 4.7 1.6e-05 24.9 3.3 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD63812.1 - 1.2e-05 24.8 6.1 0.00017 21.1 1.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD63812.1 - 1.3e-05 24.9 0.9 2.3e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMD63812.1 - 0.00078 19.1 0.5 0.00078 19.1 0.4 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD63812.1 - 0.012 15.6 1.5 0.012 15.6 1.1 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD63812.1 - 0.013 15.2 0.7 0.013 15.2 0.5 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMD63812.1 - 0.086 12.8 4.6 2.8 7.9 2.8 3.0 2 1 1 3 3 3 0 FANCL C-terminal domain RINGv PF12906.2 EMD63812.1 - 0.11 12.5 3.3 0.12 12.4 0.7 2.2 2 0 0 2 2 2 0 RING-variant domain BatA PF07584.6 EMD63812.1 - 0.8 9.9 2.6 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DDHD PF02862.12 EMD63813.1 - 3e-72 243.1 9.2 9.6e-72 241.4 0.0 2.9 2 1 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 EMD63813.1 - 0.06 13.0 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 EMD63813.1 - 0.15 11.3 0.0 0.81 8.9 0.0 2.1 3 0 0 3 3 3 0 Putative serine esterase (DUF676) DHHW PF14286.1 EMD63813.1 - 1.8 7.7 8.5 0.074 12.3 1.7 1.6 2 0 0 2 2 2 0 DHHW protein MAPEG PF01124.13 EMD63815.1 - 8.3e-16 57.7 4.9 1.6e-15 56.8 3.4 1.5 1 1 0 1 1 1 1 MAPEG family Membralin PF09746.4 EMD63815.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein ACPS PF01648.15 EMD63816.1 - 1.6e-07 31.1 0.0 1.6e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EMD63817.1 - 5.6e-54 182.6 0.0 2e-44 151.4 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMD63817.1 - 1e-09 38.1 0.0 6.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EMD63817.1 - 6.3e-05 22.5 0.1 0.00035 20.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 EMD63817.1 - 0.00068 18.9 0.1 0.0016 17.7 0.0 1.6 2 0 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD63817.1 - 0.00097 18.6 0.0 0.0022 17.4 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EMD63817.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S51 Peptidase_C26 PF07722.8 EMD63817.1 - 0.097 12.0 0.1 0.33 10.3 0.0 1.9 2 1 0 2 2 2 0 Peptidase C26 RRM_1 PF00076.17 EMD63818.1 - 1.6e-16 59.6 0.0 2.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63818.1 - 4.1e-13 49.0 0.0 6.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63818.1 - 6.1e-09 35.5 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRR1 PF07985.7 EMD63821.1 - 3.4e-08 33.2 0.0 7.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 SRR1 DUF2040 PF09745.4 EMD63822.1 - 5.1e-38 129.7 27.2 5.1e-38 129.7 18.8 4.0 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) PXA PF02194.10 EMD63823.1 - 5 6.6 10.6 0.093 12.2 1.0 2.2 2 0 0 2 2 2 0 PXA domain Glyco_hydro_11 PF00457.12 EMD63824.1 - 6.5e-77 257.0 18.6 7.6e-77 256.7 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 EBP PF05241.7 EMD63825.1 - 9.4e-73 243.3 11.4 1.1e-72 243.1 7.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein CBM_21 PF03370.8 EMD63826.1 - 2.3e-36 124.2 2.9 3.9e-36 123.4 2.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit BolA PF01722.13 EMD63830.1 - 4.2e-16 58.6 0.0 5.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein F-box-like PF12937.2 EMD63831.1 - 1.2e-06 28.1 0.2 2.8e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD63831.1 - 0.0023 17.5 0.1 0.0078 15.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain Toxin_33 PF08121.6 EMD63833.1 - 0.31 10.6 4.5 0.81 9.3 3.1 1.7 1 0 0 1 1 1 0 Waglerin family Ank_5 PF13857.1 EMD63834.1 - 1.7e-06 28.0 0.1 5.4e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EMD63834.1 - 7.6e-05 22.3 0.3 0.00018 21.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EMD63834.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD63834.1 - 0.0041 17.2 0.1 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EMD63834.1 - 0.074 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) FAD_binding_1 PF00667.15 EMD63835.1 - 4e-36 124.5 0.0 6.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD63835.1 - 2.1e-30 105.6 0.0 1.5e-29 102.7 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMD63835.1 - 1.2e-15 58.0 0.0 4.9e-15 56.0 0.0 2.1 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EMD63835.1 - 4.9e-05 22.8 0.0 0.0043 16.4 0.0 2.2 2 0 0 2 2 2 2 Flavodoxin domain Flavodoxin_5 PF12724.2 EMD63835.1 - 0.00016 21.6 0.0 0.024 14.6 0.0 2.5 1 1 0 2 2 2 1 Flavodoxin domain RRM_1 PF00076.17 EMD63836.1 - 1.1e-27 95.4 0.0 1.3e-14 53.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD63836.1 - 3.6e-22 78.1 0.0 3.6e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD63836.1 - 8.6e-08 31.9 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EMD63836.1 - 0.43 9.0 1.6 0.63 8.4 1.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Zip PF02535.17 EMD63837.1 - 2.1e-32 112.4 29.5 1.9e-30 106.0 20.4 3.3 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.4 EMD63838.1 - 1.4e-22 80.4 0.0 4.1e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 EMD63838.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Formyl_trans_N PF00551.14 EMD63839.1 - 7.9e-42 142.8 0.0 1.1e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase p450 PF00067.17 EMD63840.1 - 3e-70 237.0 0.0 3.6e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EMD63841.1 - 0.023 13.9 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Luciferase_N PF05295.6 EMD63841.1 - 0.095 12.5 0.2 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain DUF4407 PF14362.1 EMD63842.1 - 4.1 6.2 7.1 6.1 5.6 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 EMD63843.1 - 1.3e-53 177.0 21.1 2.4e-09 36.7 0.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EMD63843.1 - 3.3e-11 42.7 0.9 5.8e-11 41.9 0.6 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EMD63843.1 - 2.1e-08 32.7 8.6 0.13 10.3 0.0 5.9 1 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EMD63843.1 - 5.8e-07 29.0 0.6 1.1e-06 28.1 0.4 1.5 1 0 0 1 1 1 1 F-box domain CAP_N PF01213.14 EMD63843.1 - 0.018 14.3 1.8 0.043 13.0 1.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nucleoporin_N PF08801.6 EMD63843.1 - 0.062 12.0 2.6 0.29 9.8 0.0 2.8 2 1 0 3 3 3 0 Nup133 N terminal like Suf PF05843.9 EMD63843.1 - 0.12 12.1 0.4 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Abhydrolase_1 PF00561.15 EMD63844.1 - 5.6e-19 68.6 0.0 1.7e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD63844.1 - 1.9e-11 44.3 0.3 1.8e-10 41.0 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD63844.1 - 9.3e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase CAP_N PF01213.14 EMD63845.1 - 0.037 13.3 0.3 0.07 12.4 0.2 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCH PF00443.24 EMD63846.1 - 1.4e-43 148.9 0.4 3e-43 147.8 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EMD63846.1 - 1e-22 80.1 0.0 3.1e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EMD63846.1 - 4.5e-16 59.1 2.2 4.5e-16 59.1 1.5 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 EMD63847.1 - 3e-48 161.4 5.7 1e-16 60.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ILVD_EDD PF00920.16 EMD63849.1 - 7.6e-207 687.8 1.8 8.8e-207 687.6 1.3 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EMD63849.1 - 0.12 12.3 0.2 6.4 6.7 0.0 2.7 2 1 0 2 2 2 0 5'-nucleotidase, C-terminal domain DUF4066 PF13278.1 EMD63851.1 - 7.1e-30 103.4 0.0 1.2e-29 102.7 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD63851.1 - 7.4e-11 41.7 0.0 1.3e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EMD63851.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DAO PF01266.19 EMD63852.1 - 8.1e-58 196.0 0.2 9.9e-58 195.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD63852.1 - 1.5e-05 25.1 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD63852.1 - 2.9e-05 24.0 0.1 6.6e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD63852.1 - 4.8e-05 23.3 0.6 0.002 18.0 0.4 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD63852.1 - 5.9e-05 22.2 0.0 0.00015 20.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMD63852.1 - 0.0079 16.5 1.6 1.4 9.3 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD63852.1 - 0.016 13.7 0.5 0.08 11.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Strep_67kDa_ant PF06100.6 EMD63852.1 - 0.018 13.4 0.1 0.03 12.6 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_3 PF01494.14 EMD63852.1 - 0.044 12.8 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EMD63852.1 - 0.051 12.4 1.7 0.16 10.8 1.2 1.8 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMD63852.1 - 0.066 12.9 0.1 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ad_cyc_g-alpha PF08509.6 EMD63853.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain PRCC PF10253.4 EMD63855.1 - 2.9e-34 119.3 0.1 2.9e-34 119.3 0.1 3.0 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 EMD63856.1 - 5.1e-33 114.3 1.1 5.5e-17 61.4 1.3 2.8 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Lipase_GDSL_2 PF13472.1 EMD63857.1 - 4.6e-14 52.9 0.1 9.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD63857.1 - 6e-14 52.4 0.2 4.5e-13 49.5 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBFD_NFYB_HMF PF00808.18 EMD63858.1 - 3e-14 52.7 0.7 6e-14 51.8 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD63858.1 - 6.6e-05 22.9 0.2 0.00011 22.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acyltransferase PF01553.16 EMD63859.1 - 0.00018 20.9 0.0 0.0004 19.8 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 EMD63860.1 - 4.5e-09 36.1 15.7 4.6e-06 26.5 2.7 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD63860.1 - 3.3e-05 23.4 6.0 3.3e-05 23.4 4.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD63860.1 - 8.3e-05 22.2 6.7 8.3e-05 22.2 4.6 2.9 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMD63860.1 - 0.00014 21.6 18.1 0.00027 20.7 5.7 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 EMD63860.1 - 0.0002 20.9 3.6 0.0002 20.9 2.5 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD63860.1 - 0.00059 19.5 5.4 0.00059 19.5 3.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger SRP72 PF08492.7 EMD63860.1 - 0.13 12.6 4.0 2 8.8 0.4 2.8 2 0 0 2 2 2 0 SRP72 RNA-binding domain FYVE PF01363.16 EMD63860.1 - 0.19 11.6 14.6 0.14 12.0 3.9 3.3 2 1 1 3 3 3 0 FYVE zinc finger MFS_1 PF07690.11 EMD63861.1 - 5.5e-29 100.9 37.0 5.5e-29 100.9 25.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box PF00646.28 EMD63863.1 - 2.7e-05 23.6 0.1 2.7e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 F-box domain zf-NADH-PPase PF09297.6 EMD63863.1 - 0.11 11.9 2.8 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HAD PF12710.2 EMD63864.1 - 3e-19 69.9 0.1 9.1e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMD63864.1 - 1.1e-18 67.1 0.0 2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD63864.1 - 1.8e-13 51.4 1.5 8.9e-13 49.1 1.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD63864.1 - 4.7e-11 42.4 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMD63864.1 - 0.0014 18.2 0.7 0.015 14.9 0.2 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 EMD63865.1 - 2e-49 167.9 0.0 2.3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3593 PF12159.3 EMD63867.1 - 0.13 12.0 0.8 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) F-box PF00646.28 EMD63868.1 - 0.00031 20.2 2.1 0.00044 19.8 0.7 1.9 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.2 EMD63868.1 - 0.0056 16.3 1.2 0.0056 16.3 0.8 2.0 2 0 0 2 2 2 1 F-box-like Sec61_beta PF03911.11 EMD63869.1 - 3.1e-18 65.2 1.0 5.3e-18 64.5 0.7 1.4 1 0 0 1 1 1 1 Sec61beta family DUF3112 PF11309.3 EMD63870.1 - 0.25 11.1 7.1 2.1 8.1 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3112) AA_permease_2 PF13520.1 EMD63871.1 - 6.1e-57 193.0 46.4 8e-57 192.6 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD63871.1 - 1.8e-27 95.8 38.1 2.5e-27 95.3 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 EMD63872.1 - 2.3e-10 40.8 0.4 3.6e-05 23.9 0.0 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD63872.1 - 3.1e-10 40.3 0.1 4e-09 36.7 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD63872.1 - 1.5e-09 38.0 0.5 0.002 18.0 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD63872.1 - 4.3e-05 22.5 0.3 0.00029 19.8 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMD63872.1 - 8.9e-05 21.5 0.1 0.051 12.4 0.0 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMD63872.1 - 0.002 17.8 2.6 0.35 10.6 0.0 3.6 5 0 0 5 5 5 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMD63872.1 - 0.03 13.4 0.1 0.14 11.3 0.1 2.0 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EMD63872.1 - 0.034 13.0 2.0 0.38 9.5 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 EMD63872.1 - 0.041 12.7 0.0 3.5 6.4 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.11 EMD63872.1 - 0.078 12.4 0.0 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.14 EMD63872.1 - 0.09 10.9 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EMD63872.1 - 0.1 11.2 0.8 5.7 5.4 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Cwf_Cwc_15 PF04889.7 EMD63873.1 - 0.0048 16.6 11.0 0.0078 15.9 7.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Mitofilin PF09731.4 EMD63873.1 - 1.1 7.8 19.0 1.6 7.2 13.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2217 PF10265.4 EMD63873.1 - 9.1 4.9 8.6 13 4.3 6.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) adh_short PF00106.20 EMD63874.1 - 3.8e-19 69.2 0.1 1.8e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD63874.1 - 1.6e-09 37.7 0.1 2.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD63874.1 - 2.4e-06 27.4 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD63874.1 - 4.5e-05 22.9 0.0 6.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD63874.1 - 0.00027 19.9 0.0 0.00041 19.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD63874.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EMD63874.1 - 0.092 11.6 0.0 0.22 10.4 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein HAD_2 PF13419.1 EMD63875.1 - 1.7e-30 106.5 0.0 2.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase COesterase PF00135.23 EMD63876.1 - 1.2e-79 268.4 0.0 1.4e-79 268.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD63876.1 - 7.8e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_43 PF04616.9 EMD63877.1 - 2.6e-27 95.6 0.6 3.8e-27 95.1 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMD63877.1 - 0.095 12.0 0.4 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain PS-DH PF14765.1 EMD63878.1 - 3.6e-64 216.7 0.0 5.7e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMD63878.1 - 7e-62 208.3 0.4 2.1e-61 206.7 0.1 2.1 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EMD63878.1 - 8.7e-53 179.3 0.7 3.3e-33 115.2 0.2 3.3 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD63878.1 - 1e-51 176.1 0.1 1.7e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMD63878.1 - 5.8e-48 162.9 0.7 6.4e-47 159.5 0.2 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD63878.1 - 1.3e-37 128.2 0.0 3.2e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD63878.1 - 5.8e-15 54.9 1.7 2.6e-14 52.9 0.1 3.1 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMD63878.1 - 1.2e-11 44.9 0.0 3.5e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD63878.1 - 1.5e-10 41.0 0.0 3.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD63878.1 - 2.9e-08 34.6 0.2 1.7e-05 25.7 0.0 4.4 4 0 0 4 4 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMD63878.1 - 1.6e-06 28.3 0.1 4.9e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMD63878.1 - 1.6e-06 28.6 0.0 9.7e-06 26.1 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD63878.1 - 7.5e-06 25.6 0.0 3.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD63878.1 - 8e-06 26.2 0.0 4.9e-05 23.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EMD63878.1 - 6.7e-05 22.6 0.0 0.00021 21.0 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Saccharop_dh PF03435.13 EMD63878.1 - 7.7e-05 21.8 0.1 0.00016 20.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EMD63878.1 - 0.00023 19.9 0.1 0.00059 18.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD63878.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMD63878.1 - 0.02 15.3 0.3 0.33 11.3 0.0 2.7 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EMD63878.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCMT PF01135.14 EMD63878.1 - 0.043 13.3 0.0 0.45 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shikimate_DH PF01488.15 EMD63878.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ubie_methyltran PF01209.13 EMD63878.1 - 0.26 10.3 0.0 0.5 9.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ketoacyl-synt PF00109.21 EMD63879.1 - 2.6e-62 210.6 0.2 4.6e-62 209.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD63879.1 - 1.1e-31 110.4 0.0 2.6e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD63879.1 - 6e-31 106.7 0.1 1.5e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMD63879.1 - 1.4e-15 57.5 0.0 6.7e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EMD63879.1 - 9e-10 38.6 0.2 1.9e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EMD63879.1 - 1.8e-09 37.3 0.0 4.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD63879.1 - 1.2e-07 31.5 0.0 5.6e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD63879.1 - 3.3e-07 30.7 0.0 1.5e-06 28.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD63879.1 - 7.6e-05 23.2 0.0 0.00034 21.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EMD63879.1 - 0.00034 19.6 0.1 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EMD63879.1 - 0.0027 17.7 0.0 0.0079 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMD63879.1 - 0.016 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EMD63879.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NAD_binding_4 PF07993.7 EMD63880.1 - 3e-08 32.9 0.0 4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Fungal_trans PF04082.13 EMD63883.1 - 2.5e-22 79.0 3.8 3.5e-22 78.5 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63883.1 - 2.4e-07 30.5 9.5 4.5e-07 29.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EMD63885.1 - 3.5e-12 46.0 0.4 2.3e-11 43.3 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD63885.1 - 1.8e-10 40.4 0.1 3.3e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EMD63885.1 - 0.076 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMD63886.1 - 8.2e-16 58.1 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD63886.1 - 2.2e-12 46.2 0.0 4.3e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD63886.1 - 6.9e-09 34.9 0.0 0.0008 18.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMD63886.1 - 1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMD63886.1 - 4.4e-05 23.4 0.1 0.00013 21.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMD63886.1 - 0.0022 16.9 0.2 0.006 15.5 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 EMD63886.1 - 0.04 13.1 0.1 0.61 9.3 0.0 2.4 2 1 1 3 3 3 0 NmrA-like family KR PF08659.5 EMD63886.1 - 0.057 13.0 2.5 0.46 10.1 0.3 2.6 2 1 1 3 3 3 0 KR domain adh_short_C2 PF13561.1 EMD63886.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DIOX_N PF14226.1 EMD63887.1 - 1e-28 100.2 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD63887.1 - 2.8e-19 69.2 0.0 4.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EMD63888.1 - 1.8e-44 151.9 42.8 1.8e-44 151.9 29.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EMD63888.1 - 9.9e-20 70.8 0.1 4e-19 68.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD63888.1 - 8.9e-07 28.1 0.0 1.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase TRI12 PF06609.8 EMD63888.1 - 1.1e-06 27.1 19.2 3.8e-06 25.3 13.3 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox PF00070.22 EMD63888.1 - 0.0012 19.2 0.1 0.0026 18.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD63888.1 - 0.0016 18.4 0.4 0.0057 16.6 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD63888.1 - 0.0072 16.1 0.1 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD63888.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD63888.1 - 0.038 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMD63888.1 - 0.075 11.8 0.0 3.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Squalene epoxidase F420_oxidored PF03807.12 EMD63888.1 - 0.1 13.0 0.4 0.26 11.7 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Transferase PF02458.10 EMD63889.1 - 6.1e-17 61.1 0.0 5.5e-16 58.0 0.0 2.1 2 1 0 2 2 2 1 Transferase family Abhydrolase_4 PF08386.5 EMD63890.1 - 1.3e-18 66.7 0.0 4.7e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EMD63890.1 - 2.3e-17 63.3 0.0 6.5e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD63890.1 - 1.5e-05 24.9 0.0 8.5e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-CCHC PF00098.18 EMD63891.1 - 0.021 14.7 2.8 0.032 14.1 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DOR PF14839.1 EMD63891.1 - 0.12 12.1 6.2 0.18 11.5 4.3 1.2 1 1 0 1 1 1 0 DOR family DUF1768 PF08719.6 EMD63893.1 - 2.4e-32 111.8 0.0 3e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) 2Fe-2S_Ferredox PF11591.3 EMD63893.1 - 0.013 15.1 3.5 0.027 14.0 2.4 1.4 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide DDE_1 PF03184.14 EMD63895.1 - 1.3e-10 40.8 0.2 1.4e-10 40.6 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Fungal_trans_2 PF11951.3 EMD63898.1 - 4.8e-36 124.1 0.1 6.6e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63898.1 - 2.4e-08 33.7 11.6 4.7e-08 32.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.17 EMD63899.1 - 4.9e-24 85.3 0.0 6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PTR2 PF00854.16 EMD63902.1 - 7.4e-19 67.7 26.9 2e-09 36.7 0.4 4.1 2 1 2 4 4 4 4 POT family MFS_1 PF07690.11 EMD63902.1 - 4.8e-08 32.0 26.5 2.9e-05 22.9 4.3 3.5 2 1 2 4 4 4 3 Major Facilitator Superfamily Voltage_CLC PF00654.15 EMD63903.1 - 9.8e-92 307.6 24.1 1.2e-91 307.3 14.1 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Lipase_GDSL_2 PF13472.1 EMD63905.1 - 5.2e-25 88.6 0.1 6.9e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD63905.1 - 3.9e-18 66.1 0.0 4.9e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Prd1-P2 PF09214.6 EMD63905.1 - 0.079 11.5 0.5 0.24 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage Prd1, adsorption protein P2 UCH PF00443.24 EMD63906.1 - 2.5e-75 253.0 0.0 6.1e-75 251.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD63906.1 - 7.8e-15 55.0 0.0 2.8e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMD63906.1 - 9.3e-12 45.2 0.1 4.4e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 DUSP domain Ubiquitin_3 PF14836.1 EMD63906.1 - 0.037 13.6 0.2 0.099 12.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain gpUL132 PF11359.3 EMD63907.1 - 0.027 13.8 4.0 0.049 12.9 2.8 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3245 PF11595.3 EMD63907.1 - 0.18 12.0 1.5 0.25 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Dicty_REP PF05086.7 EMD63907.1 - 1.3 6.7 6.1 1.5 6.5 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.2 EMD63908.1 - 7.5e-17 61.4 0.0 1.4e-08 34.9 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Clr5 PF14420.1 EMD63908.1 - 7.2e-14 51.4 4.0 1.4e-13 50.4 2.8 1.5 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.25 EMD63908.1 - 1.1e-12 47.0 0.4 6.3e-05 22.5 0.0 6.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 EMD63908.1 - 6.2e-08 32.9 0.0 0.001 19.5 0.0 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD63908.1 - 9.5e-06 25.3 0.0 7.1 7.2 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 EMD63908.1 - 0.001 19.2 0.0 1.2 9.5 0.0 4.2 3 2 1 4 4 4 1 Ankyrin repeats (many copies) MFS_1 PF07690.11 EMD63909.1 - 5.2e-30 104.3 42.5 4.2e-27 94.7 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EMD63909.1 - 0.034 14.0 0.1 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HlyIII PF03006.15 EMD63910.1 - 2.6e-48 164.3 15.3 3.2e-48 164.0 10.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4149 PF13664.1 EMD63910.1 - 0.0025 17.8 7.5 0.093 12.7 0.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4149) DUF962 PF06127.6 EMD63910.1 - 0.011 15.6 1.6 0.011 15.6 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Per1 PF04080.8 EMD63910.1 - 0.02 14.3 3.2 0.024 14.0 2.2 1.2 1 0 0 1 1 1 0 Per1-like Pkinase PF00069.20 EMD63911.1 - 4.7e-71 238.9 0.3 1e-70 237.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63911.1 - 4.4e-38 130.8 0.0 7.8e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD63911.1 - 1e-05 24.6 0.0 2.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TMEM51 PF15345.1 EMD63911.1 - 0.32 10.6 11.1 0.19 11.4 6.1 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 PAT1 PF09770.4 EMD63911.1 - 0.95 7.6 25.1 1.2 7.2 17.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EMD63911.1 - 2.7 7.3 30.1 4.1 6.7 20.8 1.3 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EMD63911.1 - 7.9 6.2 30.5 12 5.7 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRP38 PF03371.10 EMD63913.1 - 2e-66 222.8 0.0 2.7e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Amidase PF01425.16 EMD63914.1 - 9.5e-61 205.9 0.3 1.5e-60 205.3 0.2 1.3 1 1 0 1 1 1 1 Amidase K_channel_TID PF07941.6 EMD63915.1 - 0.55 10.4 4.7 0.77 10.0 3.2 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PEX11 PF05648.9 EMD63916.1 - 4.3e-11 42.5 0.0 8.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1900 PF08954.6 EMD63917.1 - 1.2e-49 167.3 0.0 4.5e-49 165.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EMD63917.1 - 1.3e-35 120.8 0.1 2.4e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EMD63917.1 - 1.2e-22 78.8 6.0 2.5e-07 30.3 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EMD63917.1 - 0.0033 15.6 0.4 0.32 9.0 0.2 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ATG16 PF08614.6 EMD63917.1 - 0.028 14.2 3.7 0.043 13.6 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4404 PF14357.1 EMD63917.1 - 0.34 11.3 5.0 41 4.6 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Menin PF05053.8 EMD63917.1 - 1.5 6.9 7.4 2.1 6.4 5.1 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 EMD63917.1 - 6.4 4.9 8.7 8.2 4.5 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Kinesin PF00225.18 EMD63918.1 - 5.1e-101 337.7 0.2 5.1e-101 337.7 0.2 2.1 3 1 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EMD63918.1 - 0.025 13.7 6.1 0.38 9.8 0.6 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 EMD63918.1 - 2.3 8.3 6.2 0.92 9.6 0.2 3.2 2 2 1 4 4 4 0 AAA domain LRR_4 PF12799.2 EMD63919.1 - 5.7e-37 124.7 22.3 1.3e-09 37.4 1.3 7.4 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD63919.1 - 6.6e-22 77.0 48.9 4.2e-07 29.6 4.3 5.0 2 1 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EMD63919.1 - 8.4e-12 43.4 21.4 1.6 9.0 0.5 11.0 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.1 EMD63919.1 - 7.6e-09 34.7 20.3 1.1 9.5 0.1 9.9 4 3 5 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 EMD63919.1 - 4.7e-08 32.7 10.7 0.0037 16.8 0.4 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EMD63919.1 - 5.3e-08 31.8 13.4 8.2 7.1 0.1 9.5 10 0 0 10 10 10 2 Leucine rich repeat Acyltransferase PF01553.16 EMD63920.1 - 0.034 13.5 0.0 0.086 12.2 0.0 1.6 1 1 0 1 1 1 0 Acyltransferase NIF PF03031.13 EMD63921.1 - 2.6e-51 173.4 0.1 3.6e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase p450 PF00067.17 EMD63923.1 - 2.2e-61 207.8 0.0 2.9e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4191 PF13829.1 EMD63923.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3270 PF11674.3 EMD63924.1 - 1.8 8.6 5.3 0.43 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) CTP_synth_N PF06418.9 EMD63926.1 - 4.7e-120 399.8 1.1 6.8e-120 399.2 0.8 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EMD63926.1 - 1.3e-53 181.2 0.0 2.2e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMD63926.1 - 3.6e-07 29.8 0.0 7.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EMD63926.1 - 0.0032 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Velvet PF11754.3 EMD63927.1 - 8.4e-64 214.9 0.0 1.2e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Bin3 PF06859.7 EMD63928.1 - 3.5e-23 81.6 0.0 6.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 EMD63928.1 - 3.7e-12 46.2 0.0 4.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD63928.1 - 3e-11 43.8 0.0 5.6e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD63928.1 - 2.3e-08 34.4 0.0 3.8e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD63928.1 - 1.3e-07 31.3 0.0 0.0039 16.7 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EMD63928.1 - 3.1e-07 30.7 0.0 0.049 14.1 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_26 PF13659.1 EMD63928.1 - 1.9e-05 24.6 0.1 3.9e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EMD63928.1 - 0.00011 21.5 0.0 0.00068 19.0 0.0 2.1 2 1 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EMD63928.1 - 0.0015 17.8 0.0 0.045 13.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMD63928.1 - 0.0043 17.3 0.0 0.04 14.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD63928.1 - 0.19 10.8 0.1 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1349 PF07081.6 EMD63929.1 - 1.4e-23 83.1 0.0 7.8e-13 48.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1349) SE PF08491.5 EMD63930.1 - 8.3e-99 329.8 0.0 1.1e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EMD63930.1 - 2.5e-10 39.9 0.0 4.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD63930.1 - 5e-10 38.8 0.3 2.8e-06 26.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD63930.1 - 2.2e-06 27.0 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMD63930.1 - 2.3e-06 26.7 1.0 7e-06 25.1 0.7 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMD63930.1 - 2.3e-05 23.4 3.6 0.00011 21.1 1.1 2.1 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMD63930.1 - 9e-05 21.6 0.2 0.0005 19.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EMD63930.1 - 0.0018 18.2 0.9 0.0036 17.2 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD63930.1 - 0.002 18.0 0.1 0.0031 17.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD63930.1 - 0.01 14.3 0.4 0.015 13.7 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EMD63930.1 - 0.012 14.2 1.5 0.35 9.4 0.2 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 EMD63930.1 - 0.017 15.5 1.4 0.02 15.2 0.2 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD63930.1 - 0.024 13.5 0.9 0.48 9.2 0.2 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMD63930.1 - 0.068 12.8 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMD63930.1 - 0.44 9.8 2.1 0.42 9.9 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OAD_gamma PF04277.8 EMD63931.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4083 PF13314.1 EMD63931.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) NUDIX PF00293.23 EMD63933.1 - 5.2e-16 58.5 0.0 7.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ras PF00071.17 EMD63934.1 - 1.3e-19 70.1 0.2 2.8e-19 69.1 0.1 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMD63934.1 - 1.3e-06 28.8 0.0 5.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMD63934.1 - 0.041 13.8 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2389 PF09493.5 EMD63934.1 - 0.046 14.0 0.1 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) DIM PF08194.7 EMD63935.1 - 0.04 13.8 0.4 0.04 13.8 0.3 2.3 2 0 0 2 2 2 0 DIM protein BmKX PF09132.5 EMD63935.1 - 2.9 7.8 6.9 5.4 6.9 4.8 1.5 1 0 0 1 1 1 0 BmKX Metallophos PF00149.23 EMD63936.1 - 1.5e-09 37.5 0.5 1.4e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD63936.1 - 5.7e-07 29.4 0.3 1.9e-06 27.8 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peroxidase_2 PF01328.12 EMD63937.1 - 7.2e-12 44.5 0.4 4e-10 38.8 0.0 2.4 3 0 0 3 3 3 2 Peroxidase, family 2 CFEM PF05730.6 EMD63938.1 - 4e-11 42.5 11.8 6.4e-11 41.9 8.2 1.3 1 0 0 1 1 1 1 CFEM domain COX14 PF14880.1 EMD63938.1 - 0.02 14.4 7.1 2 8.0 0.3 3.6 3 0 0 3 3 3 0 Cytochrome oxidase c assembly GMC_oxred_C PF05199.8 EMD63939.1 - 1e-29 103.6 0.0 1.9e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMD63939.1 - 7.2e-25 87.7 0.0 5.4e-19 68.4 0.0 3.6 3 1 0 3 3 3 2 GMC oxidoreductase DAO PF01266.19 EMD63939.1 - 2.5e-05 23.3 0.0 0.00098 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD63939.1 - 0.00011 22.1 0.0 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD63939.1 - 0.00015 21.7 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD63939.1 - 0.00034 19.5 0.0 0.0035 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 EMD63939.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EMD63939.1 - 0.032 13.1 0.0 0.063 12.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pkinase PF00069.20 EMD63940.1 - 3.8e-11 42.6 0.0 2.2e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD63940.1 - 1e-05 24.7 0.0 0.004 16.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2439 PF10382.4 EMD63941.1 - 9.1e-27 93.1 0.0 1.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_1 PF00018.23 EMD63942.1 - 2.5e-13 49.1 0.0 4.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD63942.1 - 2.6e-13 49.3 0.0 4.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EMD63942.1 - 1.9e-12 47.1 3.1 2.8e-12 46.6 2.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EMD63942.1 - 1.7e-11 43.4 0.0 2.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ADIP PF11559.3 EMD63942.1 - 0.045 13.6 3.6 0.09 12.6 2.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EMD63942.1 - 0.062 12.4 11.2 0.1 11.7 5.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EI24 PF07264.6 EMD63943.1 - 0.0056 16.1 5.6 0.0056 16.1 3.9 1.7 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.4 EMD63943.1 - 0.089 11.3 2.2 0.12 10.9 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-DHHC PF01529.15 EMD63943.1 - 0.87 8.9 6.6 1.5 8.1 4.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tetraspannin PF00335.15 EMD63945.1 - 0.91 8.7 8.5 1.6 7.9 5.5 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF1049 PF06305.6 EMD63945.1 - 1.4 8.3 5.8 4.8 6.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Halogen_Hydrol PF10112.4 EMD63946.1 - 0.11 11.8 0.3 0.31 10.4 0.3 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MFS_1 PF07690.11 EMD63948.1 - 1.2e-15 57.1 30.8 1.2e-15 57.1 21.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nse4_C PF08743.5 EMD63949.1 - 2.2e-33 114.1 0.0 5.3e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EMD63949.1 - 2e-14 53.1 0.2 6.3e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Metal_resist PF13801.1 EMD63949.1 - 0.024 14.5 1.6 0.07 13.1 1.1 1.8 1 0 0 1 1 1 0 Heavy-metal resistance PI3Ka PF00613.15 EMD63950.1 - 5.1e-56 188.7 0.2 8e-56 188.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EMD63950.1 - 2.4e-39 135.2 0.0 1.3e-37 129.4 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EMD63950.1 - 3.8e-28 98.0 0.0 5.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 EMD63950.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Abhydrolase_3 PF07859.8 EMD63951.1 - 3e-15 56.3 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD63951.1 - 2.8e-08 33.6 0.0 5e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD63951.1 - 4.2e-08 32.4 0.0 5.6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMD63951.1 - 1.1e-07 31.2 0.0 0.00016 20.9 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMD63951.1 - 1.4e-07 31.6 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMD63951.1 - 4.1e-06 25.8 0.2 3.9e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.6 EMD63951.1 - 0.00011 21.1 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 EMD63951.1 - 0.00024 19.7 0.0 0.03 12.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EMD63951.1 - 0.00037 20.0 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EMD63951.1 - 0.052 12.1 0.0 2.9 6.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Esterase PF00756.15 EMD63951.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase HemY_N PF07219.8 EMD63952.1 - 0.36 10.4 5.6 0.39 10.2 3.5 1.3 1 1 0 1 1 1 0 HemY protein N-terminus Orbi_VP1 PF05788.7 EMD63953.1 - 0.088 9.9 0.0 0.088 9.9 0.0 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Cnd3 PF12719.2 EMD63954.1 - 0.037 13.0 1.0 0.038 12.9 0.7 1.0 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF4520 PF15016.1 EMD63958.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Mfp-3 PF04202.8 EMD63958.1 - 0.85 9.8 4.2 0.52 10.5 1.6 1.7 2 0 0 2 2 2 0 Foot protein 3 Glyco_hydro_32N PF00251.15 EMD63962.1 - 1.9e-79 267.2 1.0 2.5e-79 266.8 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD63962.1 - 4.5e-05 23.7 0.0 0.00028 21.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Aldo_ket_red PF00248.16 EMD63963.1 - 6.5e-33 113.7 0.0 7.8e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.17 EMD63965.1 - 1.2e-07 31.6 0.3 1.5e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EMD63965.1 - 0.042 13.8 0.3 0.061 13.3 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Fungal_trans PF04082.13 EMD63966.1 - 8.3e-09 34.6 0.3 1.4e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1446 PF07287.6 EMD63967.1 - 2.4e-68 230.2 0.1 3.6e-45 154.0 0.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1446) AMP-binding PF00501.23 EMD63968.1 - 4.2e-55 186.8 0.0 1.1e-54 185.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD63968.1 - 1.2e-10 42.2 0.4 3.7e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain REF PF05755.7 EMD63970.1 - 8.3 6.0 9.1 14 5.3 4.5 1.9 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) RNase_E_G PF10150.4 EMD63972.1 - 0.25 10.5 5.6 2.6 7.2 2.8 2.5 1 1 0 1 1 1 0 Ribonuclease E/G family Dimer_Tnp_hAT PF05699.9 EMD63973.1 - 4e-13 48.7 0.0 4.3e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_transf_25 PF01755.12 EMD63974.1 - 9.9e-13 48.1 0.0 4.5e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DDE_1 PF03184.14 EMD63976.1 - 2.3e-11 43.2 0.0 6.4e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4507 PF14964.1 EMD63976.1 - 0.4 9.3 4.6 0.56 8.8 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) LZ_Tnp_IS66 PF13007.2 EMD63976.1 - 1.4 9.6 12.4 0.098 13.3 3.7 2.6 2 1 1 3 3 3 0 Transposase C of IS166 homeodomain HDPD PF02924.9 EMD63980.1 - 0.17 11.6 1.5 0.17 11.6 1.0 1.1 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D F-box-like PF12937.2 EMD63982.1 - 0.0048 16.5 0.1 0.0088 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD63982.1 - 0.0095 15.5 0.1 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain ITI_HC_C PF06668.7 EMD63983.1 - 0.056 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Syncollin PF15138.1 EMD63983.1 - 0.062 13.1 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Syncollin Glyco_hydro_32N PF00251.15 EMD63984.1 - 1.3e-67 228.3 7.2 1.6e-67 228.0 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD63984.1 - 1e-08 35.4 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Crystall_3 PF08964.5 EMD63985.1 - 0.00011 21.8 0.4 0.00019 21.1 0.3 1.4 1 1 0 1 1 1 1 Beta/Gamma crystallin DUF4189 PF13827.1 EMD63985.1 - 0.016 15.4 0.5 0.017 15.3 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) AAA_12 PF13087.1 EMD63986.1 - 2.1e-13 50.1 0.0 3.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain zf-C3HC4_3 PF13920.1 EMD63986.1 - 0.049 13.3 0.5 0.71 9.5 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) KR PF08659.5 EMD63988.1 - 5e-26 91.4 0.0 5.8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMD63988.1 - 7e-22 78.1 0.0 8.5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase GFA PF04828.9 EMD63990.1 - 4e-06 26.6 1.0 4e-06 26.6 0.7 1.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EMD63990.1 - 0.085 12.3 6.0 0.057 12.9 2.7 1.7 2 0 0 2 2 2 0 CSL zinc finger SIR2 PF02146.12 EMD63990.1 - 0.096 12.4 0.6 0.15 11.8 0.4 1.2 1 0 0 1 1 1 0 Sir2 family Cys_rich_CWC PF14375.1 EMD63990.1 - 2.8 7.9 8.5 0.24 11.3 2.7 1.5 2 0 0 2 2 2 0 Cysteine-rich CWC DUF3632 PF12311.3 EMD63991.1 - 6.5e-18 65.1 0.0 1.2e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Cupin_2 PF07883.6 EMD63992.1 - 2e-26 91.2 1.6 3e-17 61.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EMD63992.1 - 1.3e-06 27.9 0.0 0.0034 16.8 0.0 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EMD63992.1 - 4.2e-06 26.4 0.3 0.00071 19.2 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EMD63992.1 - 5.4e-06 25.7 0.1 0.082 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.9 EMD63992.1 - 0.017 15.0 0.1 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family CENP-C_C PF11699.3 EMD63992.1 - 0.07 13.1 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Mif2/CENP-C like EutQ PF06249.7 EMD63992.1 - 0.094 12.2 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ FAA_hydrolase PF01557.13 EMD63993.1 - 1.2e-56 191.5 0.0 1.5e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TPP_enzyme_N PF02776.13 EMD63994.1 - 2.7e-40 137.6 0.1 6.2e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD63994.1 - 3.2e-18 65.8 0.0 1.7e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD63994.1 - 1.9e-14 53.5 0.0 6e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UbiD PF01977.11 EMD63995.1 - 1.9e-118 395.4 0.0 2.6e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 EMD63996.1 - 1.3e-25 89.5 0.1 1.8e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein SnoaL PF07366.7 EMD63997.1 - 7.6e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD63997.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Fungal_trans PF04082.13 EMD63998.1 - 2.7e-11 42.8 0.2 5e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD63998.1 - 5e-08 32.7 11.3 1.1e-07 31.6 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EMD63999.1 - 3.1e-22 78.5 0.0 5.5e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Aldedh PF00171.17 EMD64000.1 - 1.9e-150 501.2 0.0 2.2e-150 501.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD64000.1 - 0.028 13.6 0.0 0.066 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease_2 PF13520.1 EMD64001.1 - 5.2e-56 189.9 53.2 6.4e-56 189.6 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD64001.1 - 8.9e-27 93.5 43.9 1.1e-26 93.1 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 EMD64002.1 - 4.7e-133 443.9 0.0 5.7e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 EMD64003.1 - 3.4e-17 62.5 0.2 1.2e-16 60.7 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMD64003.1 - 3.1e-06 27.1 0.7 8.2e-06 25.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD64003.1 - 7.3e-05 21.8 6.7 0.00084 18.3 3.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD64003.1 - 0.0057 15.7 0.2 0.0093 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD64003.1 - 0.023 14.6 2.4 0.043 13.6 1.7 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD64003.1 - 0.04 14.3 0.3 0.04 14.3 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 EMD64003.1 - 0.099 12.3 0.1 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.16 EMD64003.1 - 0.1 12.1 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EMD64003.1 - 0.12 11.1 3.9 0.23 10.2 1.9 1.9 1 1 1 2 2 2 0 FAD binding domain adh_short_C2 PF13561.1 EMD64004.1 - 1.2e-31 110.3 0.2 1.4e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD64004.1 - 1.7e-30 106.1 2.4 2.2e-30 105.7 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD64004.1 - 5.9e-17 61.9 0.5 8.8e-17 61.3 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMD64004.1 - 0.0056 15.8 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMD64004.1 - 0.029 13.7 0.1 0.047 13.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF43 PF01861.11 EMD64004.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 TrkA_N PF02254.13 EMD64004.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EMD64005.1 - 7.2e-26 91.4 0.0 2.4e-24 86.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD64005.1 - 4.4e-17 62.0 0.0 7e-15 54.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EMD64005.1 - 6.8e-11 41.0 0.0 2.6e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMD64005.1 - 1.4e-10 41.4 0.0 4.8e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD64005.1 - 1.7e-07 31.1 0.6 0.0037 17.0 0.1 3.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMD64005.1 - 1.3e-06 28.3 0.6 3.6e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD64005.1 - 3.4e-06 26.2 4.7 0.0095 14.8 0.1 3.8 2 2 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMD64005.1 - 2.1e-05 23.7 1.0 0.002 17.2 0.1 2.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EMD64005.1 - 2.5e-05 24.5 1.6 0.27 11.6 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD64005.1 - 0.0028 16.2 0.9 1.4 7.2 0.0 3.3 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.19 EMD64005.1 - 0.0042 15.9 1.3 0.1 11.4 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EMD64005.1 - 0.0051 15.7 0.0 2 7.2 0.0 3.3 4 0 0 4 4 4 1 Lycopene cyclase protein GIDA PF01134.17 EMD64005.1 - 0.29 9.9 2.1 21 3.8 0.0 3.2 3 1 0 3 3 3 0 Glucose inhibited division protein A Trp_DMAT PF11991.3 EMD64006.1 - 1.6e-27 96.6 0.0 1.3e-26 93.7 0.0 2.3 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase AflR PF08493.5 EMD64008.1 - 6.4e-19 68.0 0.1 1.3e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EMD64008.1 - 5.9e-08 32.4 12.4 1.2e-07 31.4 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTSE1_N PF15259.1 EMD64008.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 PAP_central PF04928.12 EMD64008.1 - 0.12 11.1 0.1 0.27 10.0 0.1 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF1772 PF08592.6 EMD64009.1 - 2.5e-23 82.3 3.9 4e-23 81.6 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) EthD PF07110.6 EMD64009.1 - 1.8e-14 54.4 0.1 2.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 EthD domain DUF4149 PF13664.1 EMD64009.1 - 0.066 13.2 3.5 0.071 13.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) adh_short PF00106.20 EMD64010.1 - 5.8e-15 55.5 0.1 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD64010.1 - 4.1e-08 33.0 0.1 6.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Peptidase_C37 PF05416.7 EMD64010.1 - 0.097 10.9 0.0 0.15 10.3 0.0 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1632 PF07857.7 EMD64010.1 - 0.17 11.1 0.4 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 CEO family (DUF1632) LRR_1 PF00560.28 EMD64011.1 - 2.5e-15 54.1 9.4 1.3 9.3 0.0 8.5 8 1 0 8 8 8 6 Leucine Rich Repeat LRR_4 PF12799.2 EMD64011.1 - 7.7e-15 54.1 9.3 0.00013 21.5 0.2 6.2 3 3 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD64011.1 - 4.6e-14 51.9 5.3 1.4e-07 31.1 0.1 4.1 1 1 4 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 EMD64011.1 - 7.2e-05 22.3 5.3 16 6.2 0.0 7.3 8 0 0 8 8 8 1 Leucine rich repeat LRR_6 PF13516.1 EMD64011.1 - 0.00013 21.6 11.8 0.83 9.9 0.0 6.9 6 1 1 7 7 7 1 Leucine Rich repeat LRRNT_2 PF08263.7 EMD64011.1 - 0.001 18.9 0.3 0.0021 17.9 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain p450 PF00067.17 EMD64012.1 - 6.1e-23 81.0 0.1 6.5e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 EMD64013.1 - 5.5e-68 224.8 15.6 2e-19 69.3 0.0 5.0 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EMD64013.1 - 1.8e-61 202.4 10.8 1.6e-14 53.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat HET PF06985.6 EMD64013.1 - 1.1e-20 74.1 5.9 4.9e-19 68.8 4.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 EMD64013.1 - 3.2e-17 61.9 0.2 0.00011 21.7 0.0 5.2 3 1 3 6 6 6 4 TPR repeat TPR_7 PF13176.1 EMD64013.1 - 1.9e-16 58.4 6.1 0.0059 16.3 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD64013.1 - 3.2e-13 48.6 12.3 0.12 12.0 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD64013.1 - 1.6e-12 46.5 0.1 0.19 12.0 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 EMD64013.1 - 5e-12 45.0 0.1 0.15 12.5 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64013.1 - 1.5e-10 41.4 3.6 0.00091 19.8 0.1 5.8 3 1 4 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 EMD64013.1 - 1.9e-09 36.8 0.0 3.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EMD64013.1 - 2.8e-08 33.0 4.5 2.2 8.3 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_16 PF13191.1 EMD64013.1 - 4.6e-06 26.7 0.2 1.5e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Apc3 PF12895.2 EMD64013.1 - 0.00011 22.3 4.8 0.0084 16.2 0.1 3.8 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Rab5-bind PF09311.6 EMD64013.1 - 0.00054 19.9 3.1 1.1 9.1 0.0 3.8 1 1 3 4 4 4 2 Rabaptin-like protein Arch_ATPase PF01637.13 EMD64013.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EMD64013.1 - 0.003 17.7 0.0 0.016 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD64013.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 NACHT domain TPR_19 PF14559.1 EMD64013.1 - 0.0046 17.2 10.6 0.7 10.2 0.2 4.4 3 1 3 6 6 5 3 Tetratricopeptide repeat AAA_25 PF13481.1 EMD64013.1 - 0.035 13.5 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.1 EMD64013.1 - 0.046 13.5 6.4 24 5.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64013.1 - 0.054 14.1 13.2 20 6.1 0.1 6.5 3 2 4 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 EMD64013.1 - 0.3 10.9 3.8 36 4.3 0.0 4.0 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain Peptidase_S41 PF03572.13 EMD64014.1 - 1.6e-08 34.1 0.0 4.8e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Trp_DMAT PF11991.3 EMD64015.1 - 4.7e-32 111.6 0.0 2.8e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase MFS_1 PF07690.11 EMD64017.1 - 4.5e-40 137.4 48.5 4.5e-40 137.4 33.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD64017.1 - 6.2e-14 51.1 29.7 1.3e-13 50.0 20.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD64017.1 - 5.4e-13 48.3 14.4 5.4e-13 48.3 10.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter ketoacyl-synt PF00109.21 EMD64018.1 - 1.7e-58 198.1 0.0 4.7e-58 196.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD64018.1 - 2.1e-55 188.3 0.3 3.5e-55 187.5 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMD64018.1 - 1.5e-54 185.2 0.0 2.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMD64018.1 - 6.1e-54 182.4 0.2 2.1e-53 180.7 0.2 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMD64018.1 - 3.5e-41 140.9 0.3 3.6e-40 137.6 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD64018.1 - 7.6e-35 119.3 0.0 2.7e-34 117.5 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD64018.1 - 8.4e-21 73.8 0.0 3.1e-18 65.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMD64018.1 - 3.8e-15 56.1 0.0 9.4e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMD64018.1 - 9.4e-14 52.3 0.0 4.5e-13 50.2 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMD64018.1 - 3.2e-12 46.4 0.0 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD64018.1 - 1.4e-10 40.9 0.0 3.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMD64018.1 - 1.9e-09 37.2 0.1 5.3e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EMD64018.1 - 5.2e-08 33.2 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD64018.1 - 2.4e-07 31.2 0.0 8.6e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMD64018.1 - 1.3e-05 25.3 0.0 4.5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EMD64018.1 - 0.00057 20.2 0.0 0.0018 18.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMD64018.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Thiolase_N PF00108.18 EMD64018.1 - 0.062 12.2 0.0 0.062 12.2 0.0 2.1 3 0 0 3 3 3 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EMD64018.1 - 0.096 12.1 0.4 1.4 8.3 0.1 2.7 2 1 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 EMD64018.1 - 0.18 11.3 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UbiA PF01040.13 EMD64019.1 - 4.2e-09 36.0 7.1 5.3e-09 35.6 4.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF498 PF04430.9 EMD64020.1 - 2.3e-30 104.3 0.0 4.6e-30 103.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF4208 PF13907.1 EMD64021.1 - 9e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) SAP25 PF15476.1 EMD64021.1 - 0.015 14.7 0.9 0.032 13.7 0.1 1.9 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP25 Beta-lactamase PF00144.19 EMD64022.1 - 5.1e-60 203.2 0.0 6.4e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Cutinase PF01083.17 EMD64024.1 - 2.1e-28 99.2 2.2 2.7e-28 98.8 1.5 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD64024.1 - 0.076 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Glyco_hydro_43 PF04616.9 EMD64025.1 - 1.3e-29 103.1 0.4 1.9e-29 102.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GIT_SHD PF08518.6 EMD64026.1 - 6.8e-21 73.3 9.7 1.2e-14 53.3 1.0 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Filament PF00038.16 EMD64026.1 - 1e-06 28.4 18.7 0.00022 20.8 2.1 2.4 2 0 0 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 EMD64026.1 - 0.00044 20.1 31.1 0.044 13.6 6.3 3.1 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 EMD64026.1 - 0.0097 15.8 3.1 0.0097 15.8 2.2 4.4 3 1 1 4 4 4 1 bZIP transcription factor Myosin_tail_1 PF01576.14 EMD64026.1 - 0.01 13.5 29.3 0.02 12.6 20.3 1.4 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 EMD64026.1 - 0.016 14.8 36.4 0.01 15.4 9.5 2.5 1 1 0 2 2 2 0 IncA protein ADIP PF11559.3 EMD64026.1 - 0.31 10.9 30.0 0.78 9.6 5.5 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF848 PF05852.6 EMD64026.1 - 0.49 10.2 21.5 0.035 13.9 5.4 3.5 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Rootletin PF15035.1 EMD64026.1 - 0.53 10.2 30.7 1.7 8.6 9.1 3.0 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 EMD64026.1 - 0.56 10.0 16.3 4.5 7.0 0.1 4.9 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EMD64026.1 - 0.62 10.4 25.7 0.32 11.3 1.7 4.8 2 2 2 4 4 4 0 SlyX Syntaxin PF00804.20 EMD64026.1 - 0.68 10.1 25.3 1.6 8.9 2.0 4.4 3 1 1 4 4 4 0 Syntaxin Tropomyosin PF00261.15 EMD64026.1 - 0.7 8.9 32.2 0.049 12.7 7.6 3.2 2 2 0 2 2 2 0 Tropomyosin DUF1664 PF07889.7 EMD64026.1 - 0.97 9.2 15.8 0.66 9.7 0.6 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EMD64026.1 - 1.4 8.5 20.2 0.6 9.7 1.6 3.5 2 1 0 3 3 3 0 Nucleoporin complex subunit 54 HALZ PF02183.13 EMD64026.1 - 1.6 8.4 6.3 1.4 8.6 0.0 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper Laminin_II PF06009.7 EMD64026.1 - 2.2 8.0 21.2 4 7.1 1.2 3.6 3 0 0 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.15 EMD64026.1 - 2.4 7.9 27.5 1.2 8.9 7.2 4.3 2 2 0 2 2 2 0 Prefoldin subunit DUF4404 PF14357.1 EMD64026.1 - 2.8 8.4 25.2 0.29 11.5 4.0 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) DUF4200 PF13863.1 EMD64026.1 - 4.3 7.2 33.8 3.3 7.6 8.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) FUSC PF04632.7 EMD64026.1 - 9.2 4.5 10.6 7.7 4.8 5.9 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family ING PF12998.2 EMD64028.1 - 2.5e-23 82.3 2.4 2.5e-23 82.3 1.7 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMD64028.1 - 1.7e-08 34.0 9.6 2.6e-08 33.4 6.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMD64028.1 - 0.032 14.3 0.3 0.071 13.2 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain CENP-F_leu_zip PF10473.4 EMD64028.1 - 0.19 11.5 2.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 EMD64028.1 - 0.4 10.8 4.7 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cnl2_NKP2 PF09447.5 EMD64028.1 - 0.41 10.3 2.5 1.6 8.4 0.6 2.3 1 1 1 2 2 2 0 Cnl2/NKP2 family protein Hist_deacetyl PF00850.14 EMD64029.1 - 1.2e-74 251.3 0.0 1.7e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Fungal_trans PF04082.13 EMD64030.1 - 5.4e-16 58.2 0.0 1.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64030.1 - 8.8e-10 38.3 12.1 2.2e-09 37.0 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EMD64031.1 - 9.1e-39 132.4 0.1 1.3e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD64031.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD64031.1 - 0.00029 20.6 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMD64031.1 - 0.003 17.9 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EMD64031.1 - 0.06 13.3 0.1 0.24 11.4 0.1 2.1 1 1 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EMD64031.1 - 0.083 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_C PF03720.10 EMD64031.1 - 0.098 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TRI12 PF06609.8 EMD64032.1 - 2.7e-74 250.4 16.9 3.5e-74 250.0 11.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMD64032.1 - 1.7e-18 66.4 47.2 4.8e-16 58.4 34.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64032.1 - 2.3e-06 26.4 14.0 2.3e-06 26.4 9.7 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter RNA_pol_Rpc34 PF05158.7 EMD64033.1 - 8.6e-78 261.7 0.0 1.5e-77 261.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HxlR PF01638.12 EMD64033.1 - 0.0019 17.8 0.1 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 HxlR-like helix-turn-helix B-block_TFIIIC PF04182.7 EMD64033.1 - 0.0027 17.5 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EMD64033.1 - 0.0098 15.5 0.1 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.17 EMD64033.1 - 0.013 15.1 0.1 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 EMD64033.1 - 0.02 14.9 0.2 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator HTH_36 PF13730.1 EMD64033.1 - 0.029 14.5 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.1 EMD64033.1 - 0.034 14.4 0.2 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain BSMAP PF12280.3 EMD64033.1 - 0.051 13.4 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Brain specific membrane anchored protein GntR PF00392.16 EMD64033.1 - 0.06 12.8 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EMD64033.1 - 0.14 11.8 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Alk_phosphatase PF00245.15 EMD64034.1 - 6e-110 367.8 1.1 7.7e-110 367.4 0.7 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMD64034.1 - 0.00023 20.6 0.1 0.00045 19.6 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Adeno_E3 PF06040.6 EMD64034.1 - 0.022 14.7 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 protein Fungal_trans PF04082.13 EMD64035.1 - 4.9e-07 28.8 0.2 9e-07 28.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64035.1 - 1.5e-06 28.0 9.7 2.4e-06 27.3 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L34e PF01199.13 EMD64036.1 - 9.5e-38 128.3 4.4 1.3e-37 127.8 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EMD64036.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Zn_ribbon_recom PF13408.1 EMD64036.1 - 0.075 13.3 0.2 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 EMD64036.1 - 0.18 11.0 2.4 0.33 10.2 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PROCN PF08083.6 EMD64037.1 - 2.4e-222 737.6 6.9 2.4e-222 737.6 4.8 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EMD64037.1 - 4.1e-125 415.6 1.3 6.8e-125 414.9 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EMD64037.1 - 1e-93 310.9 1.2 2.2e-93 309.8 0.8 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EMD64037.1 - 2e-75 251.5 2.4 2.7e-75 251.1 0.6 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EMD64037.1 - 8.5e-67 222.9 0.1 1.7e-66 221.9 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EMD64037.1 - 8.5e-46 154.7 0.0 2.8e-45 153.0 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EMD64037.1 - 1.1e-44 150.1 0.7 3.7e-44 148.5 0.5 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 EMD64037.1 - 0.05 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) PTR2 PF00854.16 EMD64038.1 - 2e-42 145.3 15.3 3.8e-26 91.7 4.3 2.2 2 0 0 2 2 2 2 POT family CHAT PF12770.2 EMD64040.1 - 8.3e-09 34.9 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Cupin_2 PF07883.6 EMD64041.1 - 3.1e-05 23.3 0.3 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EMD64041.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.4 1 1 0 1 1 1 1 Cupin ADH_N PF08240.7 EMD64042.1 - 1.7e-11 43.8 0.0 3.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD64042.1 - 1e-08 36.1 0.0 2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD64042.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pterin_4a PF01329.14 EMD64042.1 - 0.14 11.9 0.1 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Abhydrolase_6 PF12697.2 EMD64045.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD64045.1 - 3.3e-08 33.3 0.0 2e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMD64045.1 - 0.095 12.1 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 EMD64045.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family SR-25 PF10500.4 EMD64046.1 - 0.00052 19.5 2.0 0.00099 18.6 1.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EMD64046.1 - 2.2 7.6 9.9 0.032 13.6 1.7 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TPR_11 PF13414.1 EMD64047.1 - 3.4e-62 205.9 18.2 3.2e-18 65.1 0.2 6.4 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMD64047.1 - 3.4e-50 165.6 23.1 2.3e-06 26.9 0.0 9.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMD64047.1 - 4.7e-40 132.2 19.8 5.7e-05 22.7 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 EMD64047.1 - 4.9e-19 68.0 10.0 6.3e-10 38.8 0.6 6.3 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD64047.1 - 5e-19 66.5 15.3 0.0029 17.2 0.2 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64047.1 - 1.4e-18 66.9 14.4 0.0028 18.2 0.1 6.9 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64047.1 - 2.6e-17 61.7 14.7 0.12 13.0 0.0 9.5 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMD64047.1 - 1.1e-15 56.3 6.0 0.0038 17.2 0.0 8.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD64047.1 - 1.7e-15 57.0 9.0 0.025 14.9 0.0 7.1 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMD64047.1 - 9.1e-11 41.4 1.6 0.00023 20.9 0.0 5.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD64047.1 - 1.5e-10 40.0 11.4 0.16 11.8 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMD64047.1 - 3.3e-09 36.5 13.1 0.3 11.6 0.2 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD64047.1 - 7.3e-06 26.0 14.6 0.0027 17.8 0.6 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EMD64047.1 - 0.00028 20.6 5.1 0.28 11.0 0.0 5.4 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EMD64047.1 - 0.00077 19.3 0.4 0.18 11.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EMD64047.1 - 0.0093 16.0 12.5 1.3 9.1 0.0 5.6 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMD64047.1 - 0.0095 15.7 3.2 35 4.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF384 PF04064.8 EMD64047.1 - 0.043 13.3 0.8 1.3 8.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF384) Chol_subst-bind PF09129.6 EMD64047.1 - 0.066 12.3 0.1 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding FolB PF02152.13 EMD64048.1 - 5.5e-23 81.2 0.0 9.3e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.13 EMD64049.1 - 3.4e-181 602.3 0.1 4.1e-181 602.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase C2 PF00168.25 EMD64051.1 - 5e-68 224.9 4.1 2.7e-20 71.9 0.0 5.8 6 0 0 6 6 6 5 C2 domain DUF4265 PF14085.1 EMD64052.1 - 0.042 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) CENP-F_N PF10481.4 EMD64052.1 - 0.15 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain VHS PF00790.14 EMD64053.1 - 0.072 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 VHS domain Mito_fiss_reg PF05308.6 EMD64053.1 - 0.58 9.4 3.7 0.93 8.8 2.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1593 PF07632.6 EMD64057.1 - 1.4e-97 326.0 0.0 1.8e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EMD64057.1 - 0.0012 17.3 0.0 0.0018 16.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain SNARE PF05739.14 EMD64058.1 - 0.038 13.6 7.1 0.31 10.7 0.2 3.9 3 0 0 3 3 3 0 SNARE domain AAA_13 PF13166.1 EMD64058.1 - 0.058 11.8 15.8 0.46 8.8 9.1 2.3 2 0 0 2 2 2 0 AAA domain DUF4618 PF15397.1 EMD64058.1 - 0.12 11.6 17.1 1.1 8.5 8.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) PspA_IM30 PF04012.7 EMD64058.1 - 4.8 6.4 38.9 0.1 11.9 2.8 4.1 3 1 0 4 4 4 0 PspA/IM30 family NPV_P10 PF05531.7 EMD64058.1 - 5.1 7.4 9.8 40 4.5 0.0 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein V-ATPase_G PF03179.10 EMD64058.1 - 6 7.2 24.8 0.11 12.7 7.7 3.3 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit NPP1 PF05630.6 EMD64059.1 - 1.8e-59 200.9 0.0 2.2e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Metallophos PF00149.23 EMD64060.1 - 1e-12 47.8 2.3 8.3e-12 44.9 1.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD64060.1 - 1.2e-07 31.6 0.0 8.9e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SGL PF08450.7 EMD64061.1 - 1.6e-21 76.7 0.1 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMD64061.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Arylesterase zf-CCCH PF00642.19 EMD64062.1 - 1.5e-08 34.1 17.1 2.8e-07 30.0 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EMD64062.1 - 3.5e-08 33.1 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD64062.1 - 4.8e-06 26.1 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64062.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2306 PF10067.4 EMD64063.1 - 0.016 15.3 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Neurensin PF14927.1 EMD64063.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Neurensin DUF3040 PF11239.3 EMD64063.1 - 0.16 12.0 0.2 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3605 PF12239.3 EMD64065.1 - 9.9e-58 194.4 4.8 1.2e-57 194.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) HMG-CoA_red PF00368.13 EMD64066.1 - 2e-154 513.7 4.8 6.4e-154 512.1 3.9 1.4 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EMD64066.1 - 9.3e-40 135.8 1.1 2.2e-39 134.6 0.8 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EMD64066.1 - 3.6e-16 58.9 3.7 8.1e-16 57.8 2.6 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMD64066.1 - 2.3e-06 25.8 3.4 2.3e-06 25.8 2.4 1.8 2 0 0 2 2 2 1 Patched family Pkinase PF00069.20 EMD64067.1 - 3.6e-71 239.3 0.0 5e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64067.1 - 1.3e-36 126.0 0.0 3.5e-36 124.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD64067.1 - 0.00066 18.7 1.1 0.53 9.2 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EMD64067.1 - 0.0025 17.6 0.3 0.85 9.3 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4611 PF15387.1 EMD64067.1 - 0.037 14.1 0.6 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SET PF00856.23 EMD64068.1 - 2.1e-12 47.6 0.0 2.9e-07 30.9 0.0 2.3 2 1 0 2 2 2 2 SET domain Metallopep PF12044.3 EMD64069.1 - 7.5e-134 446.3 0.0 9.5e-134 446.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 EMD64069.1 - 0.062 13.3 0.4 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMD64069.1 - 0.087 13.3 0.1 0.26 11.8 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Orbi_VP7 PF00897.12 EMD64071.1 - 0.14 11.1 0.1 0.33 9.8 0.0 1.6 2 0 0 2 2 2 0 Orbivirus inner capsid protein VP7 Glyco_hydro_76 PF03663.9 EMD64072.1 - 1.6e-78 264.6 6.1 2.1e-78 264.3 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Peptidase_M30 PF10460.4 EMD64073.1 - 0.042 12.7 0.2 0.054 12.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase M30 Pectate_lyase PF03211.8 EMD64074.1 - 4.9e-66 222.2 7.4 6.3e-66 221.8 5.2 1.0 1 0 0 1 1 1 1 Pectate lyase Fungal_trans_2 PF11951.3 EMD64075.1 - 4.1e-08 32.2 0.0 5.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64075.1 - 0.00025 20.8 10.6 0.00042 20.1 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8_N PF14482.1 EMD64076.1 - 0.04 13.9 0.2 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain IL4Ra_N PF09238.5 EMD64076.1 - 0.051 13.6 0.2 0.075 13.1 0.2 1.3 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal Ssu72 PF04722.8 EMD64077.1 - 4.7e-82 274.0 0.0 5.5e-82 273.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_9 PF14604.1 EMD64078.1 - 1.8e-10 40.2 0.1 1.8e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMD64078.1 - 1.5e-09 37.0 0.0 3.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD64078.1 - 4.1e-06 26.1 0.0 8.2e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Abhydrolase_6 PF12697.2 EMD64079.1 - 2.8e-25 89.5 0.5 5.3e-25 88.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD64079.1 - 8.8e-16 57.9 0.0 3.3e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EMD64079.1 - 7e-12 45.0 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EMD64079.1 - 2.8e-06 27.0 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMD64079.1 - 0.00032 21.0 0.1 0.00058 20.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.22 EMD64079.1 - 0.0011 18.4 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.8 EMD64079.1 - 0.0014 18.3 0.0 0.0049 16.4 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.1 EMD64079.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Lipase_3 PF01764.20 EMD64079.1 - 0.0037 16.8 0.2 0.018 14.6 0.0 1.9 1 1 1 2 2 2 1 Lipase (class 3) LCAT PF02450.10 EMD64079.1 - 0.0039 16.2 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Esterase PF00756.15 EMD64079.1 - 0.0044 16.4 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 EMD64079.1 - 0.0062 16.1 0.3 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 EMD64079.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EMD64079.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ILVD_EDD PF00920.16 EMD64080.1 - 2.9e-200 666.1 3.5 3.4e-200 665.9 2.4 1.0 1 0 0 1 1 1 1 Dehydratase family Inhibitor_I78 PF11720.3 EMD64080.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Ribosomal_S19e PF01090.14 EMD64081.1 - 5.6e-57 191.0 0.2 6.4e-57 190.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e BNR_2 PF13088.1 EMD64082.1 - 0.0001 21.7 0.1 0.0016 17.7 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EMD64082.1 - 0.014 15.1 6.0 0.65 10.0 0.1 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyco_hydro_61 PF03443.9 EMD64084.1 - 2.6e-70 236.6 1.7 3.1e-70 236.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_C7 PF01830.13 EMD64085.1 - 0.077 12.1 1.5 1.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase C7 family UPAR_LY6 PF00021.16 EMD64085.1 - 0.18 12.2 1.6 0.17 12.2 0.3 1.6 2 0 0 2 2 2 0 u-PAR/Ly-6 domain TFR_dimer PF04253.10 EMD64086.1 - 7e-21 74.0 0.0 1.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMD64086.1 - 1e-17 64.4 0.0 2.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMD64086.1 - 1.5e-06 27.7 0.2 4e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EMD64086.1 - 0.042 13.0 0.3 0.085 12.0 0.0 1.5 2 0 0 2 2 2 0 Nicastrin His_Phos_1 PF00300.17 EMD64087.1 - 0.054 13.5 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Slx4 PF09494.5 EMD64088.1 - 3.5e-15 55.5 3.7 5.4e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Slx4 endonuclease Zn_clus PF00172.13 EMD64089.1 - 3.5e-07 30.0 15.5 7.3e-07 28.9 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.9 EMD64090.1 - 4.4e-98 327.8 0.4 7e-98 327.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMD64090.1 - 5.2e-38 130.3 0.0 9.2e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase PAT1 PF09770.4 EMD64091.1 - 0.4 8.8 31.7 0.46 8.6 22.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_67N PF03648.9 EMD64092.1 - 0.0059 16.6 0.1 0.023 14.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus DUF2462 PF09495.5 EMD64093.1 - 3e-15 56.6 4.7 3.5e-15 56.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF2413 PF10310.4 EMD64094.1 - 2.4e-146 488.0 1.9 5.1e-146 486.9 1.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) TFIIA PF03153.8 EMD64094.1 - 0.00027 20.9 6.7 0.00027 20.9 4.7 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Flu_M1_C PF08289.6 EMD64094.1 - 0.021 14.8 0.2 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Sigma70_ner PF04546.8 EMD64094.1 - 0.044 13.3 8.8 0.015 14.9 3.6 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 EMD64094.1 - 0.048 13.4 3.3 0.086 12.6 2.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal S-antigen PF05756.6 EMD64094.1 - 0.11 12.4 2.1 0.31 11.0 1.5 1.7 1 0 0 1 1 1 0 S-antigen protein Nop14 PF04147.7 EMD64094.1 - 0.11 10.3 8.6 0.18 9.7 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EMD64094.1 - 0.29 10.8 1.2 0.91 9.1 0.8 1.8 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 EMD64094.1 - 1.9 6.5 2.9 2.8 5.9 2.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EMD64094.1 - 2.8 5.8 7.9 5.9 4.7 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EMD64094.1 - 3.6 6.7 11.3 5.8 6.0 7.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EMD64094.1 - 3.9 6.9 17.3 7 6.1 12.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Transp_cyt_pur PF02133.10 EMD64096.1 - 1.2e-17 63.5 45.7 2.8e-17 62.3 31.7 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amino_oxidase PF01593.19 EMD64097.1 - 4e-63 214.0 0.2 1.4e-50 172.7 0.1 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD64097.1 - 6.8e-12 45.2 0.1 1.9e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD64097.1 - 5.7e-05 22.1 0.0 0.022 13.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD64097.1 - 0.00044 20.6 0.0 0.02 15.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD64097.1 - 0.0019 18.2 0.0 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD64097.1 - 0.0026 16.7 0.0 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMD64097.1 - 0.0026 16.8 0.1 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMD64097.1 - 0.0038 17.0 0.5 0.63 9.7 0.1 2.8 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD64097.1 - 0.0082 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD64097.1 - 0.029 12.8 1.3 0.039 12.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EMD64097.1 - 0.033 13.0 1.1 0.068 12.0 0.8 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMD64097.1 - 0.053 12.6 0.1 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EMD64097.1 - 0.061 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMD64097.1 - 0.087 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EMD64097.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Exo_endo_phos PF03372.18 EMD64098.1 - 2.1e-06 27.8 0.1 2.8e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FtsZ_C PF12327.3 EMD64098.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Peptidase_C14 PF00656.17 EMD64099.1 - 1.9e-48 165.3 0.0 2.5e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Hist_deacetyl PF00850.14 EMD64100.1 - 7e-81 271.8 0.0 1.2e-80 271.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EMD64101.1 - 4.7e-35 119.7 0.1 8.3e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMD64101.1 - 5.8e-26 90.8 0.8 1.3e-25 89.7 0.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EMD64101.1 - 8.5e-10 38.1 0.0 1.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ABC_tran PF00005.22 EMD64102.1 - 2.4e-32 112.0 0.0 5.6e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMD64102.1 - 1.4e-29 103.3 5.5 1.4e-29 103.3 3.8 2.3 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EMD64102.1 - 7.2e-07 28.6 0.0 2.3e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD64102.1 - 0.00013 22.0 0.0 0.043 13.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EMD64102.1 - 0.0029 17.4 0.2 0.029 14.2 0.1 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EMD64102.1 - 0.015 14.4 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMD64102.1 - 0.03 13.8 0.1 0.075 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 EMD64103.1 - 2.5e-22 77.8 8.3 2e-08 33.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EMD64103.1 - 2.8e-07 30.4 0.0 0.0047 16.6 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EMD64103.1 - 0.1 10.4 0.0 0.15 9.7 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Ribosomal_S21e PF01249.13 EMD64105.1 - 9.1e-40 134.4 0.0 1e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro_7 PF00840.15 EMD64106.1 - 6.8e-128 426.7 9.7 8.1e-128 426.4 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Ribosomal_L14 PF00238.14 EMD64107.1 - 1.1e-32 112.2 0.0 1.3e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e GMC_oxred_N PF00732.14 EMD64109.1 - 6e-65 219.2 0.1 1.3e-64 218.2 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD64109.1 - 6.3e-36 123.8 0.2 1.3e-35 122.7 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMD64109.1 - 3.1e-09 36.2 0.0 0.00069 18.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD64109.1 - 1.3e-07 30.8 0.3 5.6e-07 28.7 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD64109.1 - 0.00075 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD64109.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMD64109.1 - 0.0039 17.5 0.2 3.6 8.0 0.0 3.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD64109.1 - 0.017 15.1 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 EMD64109.1 - 0.038 13.0 0.7 0.058 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Metallophos PF00149.23 EMD64110.1 - 3e-06 26.7 1.6 1.3e-05 24.7 1.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Med17 PF10156.4 EMD64110.1 - 0.13 10.4 0.2 0.2 9.8 0.2 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex ENTH PF01417.15 EMD64111.1 - 7.9e-48 161.4 0.5 1.1e-47 160.9 0.4 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMD64111.1 - 0.00058 18.6 0.1 0.00082 18.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.16 EMD64112.1 - 1.8e-39 135.4 0.2 2.4e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cys_Met_Meta_PP PF01053.15 EMD64113.1 - 3.2e-62 210.0 0.0 1e-61 208.3 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMD64113.1 - 0.001 17.9 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Lamprin PF06403.6 EMD64114.1 - 0.031 14.0 1.6 0.05 13.3 1.1 1.5 1 1 0 1 1 1 0 Lamprin S_tail_recep_bd PF14928.1 EMD64114.1 - 0.05 13.7 0.1 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Spc24 PF08286.6 EMD64118.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 zf-CCHC PF00098.18 EMD64120.1 - 2.3e-06 27.2 2.0 3.6e-06 26.6 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle OrfB_Zn_ribbon PF07282.6 EMD64120.1 - 0.081 12.5 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_2 PF13696.1 EMD64120.1 - 0.13 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EMD64120.1 - 0.18 11.4 0.9 0.31 10.7 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 EMD64121.1 - 0.027 14.3 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease HTH_37 PF13744.1 EMD64122.1 - 0.00083 19.1 0.3 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain G-gamma PF00631.17 EMD64122.1 - 0.036 13.7 0.7 0.053 13.2 0.5 1.2 1 0 0 1 1 1 0 GGL domain RsbRD_N PF14361.1 EMD64122.1 - 0.051 14.0 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Zn_clus PF00172.13 EMD64123.1 - 0.3 11.0 6.5 0.9 9.5 4.5 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1289 PF06945.8 EMD64123.1 - 1 8.8 4.7 3.6 7.1 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1289) Sulf_transp PF04143.9 EMD64125.1 - 2.7e-16 59.3 23.8 1.1e-08 34.9 3.7 3.4 3 0 0 3 3 3 2 Sulphur transport DUF4341 PF14241.1 EMD64125.1 - 4.7e-10 39.0 0.0 4.7e-10 39.0 0.0 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) Diphthamide_syn PF01866.12 EMD64126.1 - 2.9e-103 345.3 0.0 3.8e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MgsA_C PF12002.3 EMD64127.1 - 4.1e-60 202.2 0.7 6.6e-60 201.6 0.1 1.6 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EMD64127.1 - 4.4e-15 56.0 0.1 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMD64127.1 - 4e-09 35.8 0.0 8.4e-09 34.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMD64127.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD64127.1 - 2.9e-05 24.1 1.0 0.00013 21.9 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD64127.1 - 7e-05 22.9 0.4 0.00036 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMD64127.1 - 7e-05 22.0 0.1 0.088 11.9 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMD64127.1 - 0.00012 21.7 0.8 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 EMD64127.1 - 0.00035 20.1 0.0 0.0042 16.5 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EMD64127.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMD64127.1 - 0.00098 18.7 0.0 0.0033 17.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EMD64127.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMD64127.1 - 0.0021 18.8 0.0 0.0058 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EMD64127.1 - 0.0064 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_10 PF12846.2 EMD64127.1 - 0.013 14.9 0.1 4.9 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EMD64127.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EMD64127.1 - 0.025 14.6 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EMD64127.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD64127.1 - 0.038 13.6 0.1 0.94 9.1 0.1 2.5 1 1 1 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EMD64127.1 - 0.048 12.7 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EMD64127.1 - 0.069 12.5 0.2 0.37 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.8 EMD64127.1 - 0.075 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 EMD64127.1 - 0.095 12.5 0.1 13 5.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EMD64127.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Peptidase_S8 PF00082.17 EMD64127.1 - 0.12 11.5 1.3 0.3 10.2 0.3 2.1 2 0 0 2 2 2 0 Subtilase family RNA_helicase PF00910.17 EMD64127.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Med3 PF11593.3 EMD64127.1 - 3.5 6.7 11.7 6.6 5.8 8.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aminotran_1_2 PF00155.16 EMD64128.1 - 4.3e-71 239.7 0.0 4.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMD64128.1 - 1e-07 31.3 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMD64128.1 - 1.8e-05 24.0 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMD64128.1 - 0.00031 19.1 0.0 0.00068 18.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMD64128.1 - 0.0033 16.2 0.0 0.0065 15.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V GDI PF00996.13 EMD64129.1 - 9.9e-41 139.4 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 EMD64129.1 - 0.044 12.7 0.2 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Amidohydro_4 PF13147.1 EMD64130.1 - 1.6e-07 31.6 2.9 5.8e-07 29.8 2.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMD64130.1 - 0.00074 19.2 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD64130.1 - 0.005 16.0 0.7 0.22 10.7 0.0 2.7 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_1 PF01979.15 EMD64130.1 - 0.013 15.1 0.1 0.043 13.4 0.1 1.8 1 1 0 1 1 1 0 Amidohydrolase family DUF1052 PF06319.7 EMD64130.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) C2 PF00168.25 EMD64131.1 - 7.1e-22 77.0 0.0 6.1e-15 54.8 0.0 2.9 3 0 0 3 3 3 2 C2 domain Ribonuclease_3 PF00636.21 EMD64133.1 - 4.1e-42 143.2 0.0 4.5e-21 75.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMD64133.1 - 8.5e-24 83.9 0.3 4.5e-11 42.7 0.0 4.0 2 2 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EMD64133.1 - 6.2e-21 73.9 0.0 1.5e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 EMD64133.1 - 8.4e-18 64.4 0.0 1.8e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD64133.1 - 6.6e-14 51.5 0.0 2.5e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD64133.1 - 1.4e-12 47.8 0.0 3.9e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Proteasome PF00227.21 EMD64134.1 - 3.3e-56 189.5 0.0 4.9e-32 110.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EMD64134.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 EMD64134.1 - 0.0067 14.9 0.5 1.3 7.3 0.0 2.2 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family RINGv PF12906.2 EMD64135.1 - 7.5e-10 38.7 3.4 4.5e-09 36.1 0.8 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EMD64135.1 - 0.0011 18.7 3.3 0.011 15.5 0.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-BED PF02892.10 EMD64135.1 - 0.03 14.0 0.9 0.073 12.8 0.1 2.0 2 0 0 2 2 2 0 BED zinc finger PHD PF00628.24 EMD64135.1 - 0.9 9.2 4.9 0.5 10.1 1.6 1.8 2 0 0 2 2 2 0 PHD-finger GAS2 PF02187.12 EMD64136.1 - 2.1e-05 24.2 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Peptidase_M28 PF04389.12 EMD64138.1 - 6e-17 61.9 0.0 1.5e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 EMD64138.1 - 1.1e-15 57.3 0.0 1.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EMD64138.1 - 0.0001 21.9 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMD64138.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CFEM PF05730.6 EMD64139.1 - 2.1e-11 43.4 7.4 4.2e-11 42.4 5.1 1.5 1 0 0 1 1 1 1 CFEM domain EPV_E5 PF08135.6 EMD64139.1 - 4.7 7.2 7.5 2.3 8.2 0.0 3.3 3 0 0 3 3 3 0 Major transforming protein E5 family MFS_1 PF07690.11 EMD64140.1 - 7.7e-18 64.3 59.6 2.8e-17 62.4 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EMD64141.1 - 1.5e-43 149.0 0.3 6.5e-43 146.9 0.2 1.8 1 1 1 2 2 2 1 Cytochrome P450 Apolipoprotein PF01442.13 EMD64141.1 - 0.0092 15.5 0.1 1.1 8.7 0.0 2.4 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain UvrD-helicase PF00580.16 EMD64141.1 - 0.072 12.3 0.1 0.092 12.0 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain A2M_comp PF07678.9 EMD64141.1 - 0.09 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 A-macroglobulin complement component LtrA PF06772.6 EMD64142.1 - 2.6e-17 62.7 22.9 2.6e-17 62.7 15.9 2.0 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) MFS_1 PF07690.11 EMD64143.1 - 7.5e-36 123.5 8.6 7.5e-36 123.5 6.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64143.1 - 1e-15 57.3 4.5 1e-15 57.3 3.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD64143.1 - 4.5e-10 38.5 3.9 2.6e-06 26.1 2.7 3.6 1 1 0 2 2 2 1 MFS/sugar transport protein Folate_carrier PF01770.13 EMD64143.1 - 0.00018 20.1 0.1 0.00032 19.3 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier TRI12 PF06609.8 EMD64143.1 - 0.011 13.9 0.7 0.02 13.0 0.5 1.4 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMD64143.1 - 0.021 14.5 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 MFS_1 like family DUF4066 PF13278.1 EMD64144.1 - 2.1e-22 79.1 0.0 3.9e-22 78.2 0.0 1.6 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD64144.1 - 1.8e-09 37.2 0.0 2.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EMD64144.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I RGS PF00615.14 EMD64146.1 - 9.9e-06 25.6 0.0 0.00071 19.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4341 PF14241.1 EMD64146.1 - 2.4 7.9 12.9 0.083 12.6 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) NAD_binding_8 PF13450.1 EMD64148.1 - 1.4e-13 50.6 0.0 2.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMD64148.1 - 2.8e-06 26.7 0.0 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMD64148.1 - 2.8e-05 24.0 0.0 0.0006 19.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD64148.1 - 6.3e-05 22.0 0.0 0.00028 19.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD64148.1 - 0.00017 21.3 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD64148.1 - 0.00038 20.5 0.0 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD64148.1 - 0.0012 17.1 0.0 0.0018 16.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.19 EMD64148.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD64148.1 - 0.0073 16.6 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EMD64148.1 - 0.011 14.1 0.0 0.017 13.5 0.0 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Thi4 PF01946.12 EMD64148.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD64148.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein V-SNARE PF05008.10 EMD64149.1 - 2.7e-21 75.5 4.2 2.7e-21 75.5 2.9 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EMD64149.1 - 3.7e-18 65.3 7.4 3.7e-18 65.3 5.1 2.9 5 0 0 5 5 5 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMD64149.1 - 0.008 15.8 0.3 0.008 15.8 0.2 2.5 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EMD64149.1 - 0.031 12.3 0.6 0.14 10.1 0.1 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 Flu_NS2 PF00601.14 EMD64149.1 - 0.036 14.2 1.8 0.1 12.8 0.2 2.2 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) Synaptobrevin PF00957.16 EMD64149.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.7 3 0 0 3 3 3 0 Synaptobrevin Prominin PF05478.6 EMD64149.1 - 0.14 9.6 2.1 3.9 4.8 0.1 2.0 2 0 0 2 2 2 0 Prominin DUF4332 PF14229.1 EMD64149.1 - 0.44 10.5 4.6 0.4 10.6 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4332) YqjK PF13997.1 EMD64149.1 - 0.53 10.4 0.1 0.53 10.4 0.1 2.2 3 0 0 3 3 3 0 YqjK-like protein Use1 PF09753.4 EMD64149.1 - 1.5 8.2 7.6 1 8.7 0.1 2.5 1 1 1 2 2 2 0 Membrane fusion protein Use1 ZapA PF05164.8 EMD64149.1 - 4 7.4 6.8 1.2 9.1 0.1 2.9 2 1 0 2 2 2 0 Cell division protein ZapA DUF883 PF05957.8 EMD64149.1 - 5.2 7.5 8.4 1.7 9.1 0.3 3.0 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Fungal_trans PF04082.13 EMD64151.1 - 4.9e-31 107.5 0.0 7.6e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain YtzH PF14165.1 EMD64151.1 - 0.059 13.6 0.2 8 6.7 0.0 2.4 2 0 0 2 2 2 0 YtzH-like protein p450 PF00067.17 EMD64152.1 - 3.4e-43 147.8 0.0 1.5e-25 89.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Abhydrolase_5 PF12695.2 EMD64153.1 - 3.6e-19 68.9 0.1 4.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD64153.1 - 1e-08 35.3 2.1 1.5e-05 25.0 1.5 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD64153.1 - 2.7e-05 23.4 0.0 0.0081 15.3 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EMD64153.1 - 5.2e-05 22.6 0.0 7.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMD64153.1 - 0.00066 19.3 0.0 0.0092 15.5 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMD64153.1 - 0.012 15.9 0.2 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.6 EMD64153.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PhoPQ_related PF10142.4 EMD64153.1 - 0.067 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Lipase_3 PF01764.20 EMD64153.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EMD64153.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NUC173 PF08161.7 EMD64154.1 - 1.4e-81 272.5 0.3 2.6e-76 255.4 0.0 3.5 3 0 0 3 3 3 2 NUC173 domain DOCK-C2 PF14429.1 EMD64155.1 - 2.5e-29 102.2 0.0 8.8e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EMD64155.1 - 4.5e-09 35.8 0.0 1.3e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EMD64155.1 - 0.00081 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD64155.1 - 0.03 13.9 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain WbqC PF08889.6 EMD64155.1 - 0.059 12.8 0.2 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 WbqC-like protein family Ribosomal_L30 PF00327.15 EMD64157.1 - 1.9e-14 52.9 0.2 2.4e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SART-1 PF03343.8 EMD64158.1 - 5.6e-157 523.7 70.6 6.4e-157 523.5 49.0 1.0 1 0 0 1 1 1 1 SART-1 family DUF2650 PF10853.3 EMD64159.1 - 0.14 11.5 1.2 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) L51_S25_CI-B8 PF05047.11 EMD64160.1 - 7.7e-17 60.7 0.0 1.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain WD40 PF00400.27 EMD64161.1 - 4.4e-17 61.2 2.5 0.0079 16.0 0.1 7.1 6 1 1 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 EMD64161.1 - 2.2e-12 46.9 0.0 6.6e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 EMD64161.1 - 0.02 14.4 0.0 13 5.4 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.10 EMD64161.1 - 0.86 9.4 5.8 0.45 10.3 0.4 2.7 2 1 1 3 3 3 0 Prp18 domain RRM_1 PF00076.17 EMD64162.1 - 9.1e-17 60.4 0.0 1.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64162.1 - 2.2e-11 43.5 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD64162.1 - 2.1e-08 33.8 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B12D PF06522.6 EMD64163.1 - 9.2e-08 31.6 0.2 2.4e-07 30.3 0.0 1.8 2 1 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1212 PF06738.7 EMD64163.1 - 0.067 12.6 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) COX6B PF02297.12 EMD64164.1 - 6.2e-20 70.9 4.9 7.2e-20 70.7 3.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EMD64164.1 - 0.0013 18.0 0.6 0.002 17.5 0.4 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain UCR_hinge PF02320.11 EMD64164.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DnaJ PF00226.26 EMD64165.1 - 1.6e-09 37.3 0.6 1.1e-08 34.7 0.4 2.2 1 1 0 1 1 1 1 DnaJ domain POP1 PF06978.6 EMD64166.1 - 6.8e-56 188.8 10.6 6.8e-56 188.8 7.4 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EMD64166.1 - 4.8e-30 103.2 1.4 4.8e-30 103.2 1.0 2.5 3 0 0 3 3 3 1 POPLD (NUC188) domain Sgf11 PF08209.6 EMD64166.1 - 1.7e-13 49.5 1.5 2.2e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EMD64166.1 - 1.2 8.9 8.9 0.097 12.3 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TPR_1 PF00515.23 EMD64169.1 - 4.5e-57 187.4 24.5 8e-09 34.7 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMD64169.1 - 9.4e-48 156.3 19.4 3.1e-06 26.6 0.0 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EMD64169.1 - 4.3e-46 154.4 18.7 1.3e-12 47.1 0.7 6.4 2 2 4 7 7 7 7 TPR repeat TPR_8 PF13181.1 EMD64169.1 - 1.6e-39 130.7 12.7 7.5e-06 25.3 0.5 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EMD64169.1 - 9.5e-31 103.4 16.3 1.7e-05 24.6 0.1 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMD64169.1 - 2.6e-30 104.1 20.5 1.1e-06 28.4 1.0 7.3 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64169.1 - 5.1e-29 100.2 16.3 1.1e-08 35.4 0.1 6.8 4 2 4 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMD64169.1 - 8.5e-26 87.6 11.0 0.0015 18.2 0.0 9.6 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64169.1 - 1.6e-25 87.2 15.6 7.5e-05 23.0 0.0 9.9 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMD64169.1 - 8.4e-23 80.4 11.7 6.7e-05 23.1 0.0 7.3 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EMD64169.1 - 3.7e-22 77.2 20.8 0.0018 18.5 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMD64169.1 - 2.2e-15 56.2 8.6 0.0004 20.1 0.1 6.9 2 1 6 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EMD64169.1 - 3.8e-13 49.3 9.8 1.3e-08 34.8 1.7 4.5 3 3 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EMD64169.1 - 2.3e-11 43.2 8.2 0.00062 18.9 1.3 4.5 1 1 2 4 4 4 4 Tetratricopeptide repeat BTAD PF03704.12 EMD64169.1 - 0.0017 18.6 4.5 2.4 8.4 0.0 3.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DUF2225 PF09986.4 EMD64169.1 - 0.004 16.6 2.7 0.14 11.5 0.0 3.0 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 EMD64169.1 - 0.012 15.5 16.0 0.66 9.9 2.1 4.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMD64169.1 - 0.088 12.9 0.0 0.088 12.9 0.0 4.5 5 1 1 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EMD64169.1 - 0.22 10.2 1.4 8.8 4.9 0.1 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EMD64169.1 - 0.35 10.8 16.5 18 5.4 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.1 EMD64169.1 - 1.3 8.0 20.0 4.9 6.2 0.5 5.0 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP NuiA PF07924.6 EMD64170.1 - 0.0018 18.1 1.4 0.52 10.2 0.0 2.2 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein DUF1888 PF08985.6 EMD64170.1 - 0.071 12.7 0.0 0.39 10.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1888) SKN1 PF03935.10 EMD64172.1 - 4.6e-231 767.2 0.3 5.4e-231 767.0 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) p450 PF00067.17 EMD64174.1 - 3.9e-41 141.0 0.0 5.6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DJ-1_PfpI PF01965.19 EMD64176.1 - 4.5e-27 94.3 0.0 5.5e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EMD64176.1 - 7.4e-11 41.5 0.0 1.3e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DUF4231 PF14015.1 EMD64176.1 - 0.00064 19.6 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) GATase_3 PF07685.9 EMD64176.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATA PF00320.22 EMD64177.1 - 8.4e-17 60.2 2.1 1.7e-16 59.2 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EMD64177.1 - 1.4e-13 50.1 4.8 2.4e-13 49.3 3.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DASH_Hsk3 PF08227.6 EMD64181.1 - 4.4e-19 68.4 3.2 5.6e-19 68.0 2.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ADIP PF11559.3 EMD64181.1 - 0.02 14.7 0.0 0.025 14.5 0.0 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 EMD64181.1 - 0.033 14.1 0.1 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 FlxA-like protein RskA PF10099.4 EMD64182.1 - 0.049 13.3 0.2 0.054 13.2 0.2 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HSDR_N_2 PF13588.1 EMD64182.1 - 0.14 11.9 0.5 0.19 11.5 0.3 1.3 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) FTR1 PF03239.9 EMD64182.1 - 0.33 9.8 1.5 0.53 9.1 1.0 1.5 1 1 0 1 1 1 0 Iron permease FTR1 family Sugar_tr PF00083.19 EMD64183.1 - 1.1e-76 258.2 27.1 1.4e-76 257.9 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD64183.1 - 9.9e-27 93.5 27.1 9.9e-27 93.5 18.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD64183.1 - 1.2e-07 30.4 1.0 2e-07 29.6 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_3 PF07859.8 EMD64184.1 - 6.8e-39 133.6 0.2 5.2e-27 94.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMD64184.1 - 0.012 14.2 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) HMG_box PF00505.14 EMD64185.1 - 6.4e-23 80.8 1.1 1.4e-22 79.7 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD64185.1 - 1.5e-06 28.4 0.3 3.2e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain SPO22 PF08631.5 EMD64186.1 - 2.3e-58 197.5 3.3 2.3e-58 197.5 2.3 3.7 5 0 0 5 5 5 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EMD64186.1 - 1e-06 28.5 12.6 0.00013 21.7 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD64186.1 - 0.0012 18.5 14.0 0.58 10.2 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TFIID_90kDa PF04494.10 EMD64186.1 - 0.042 13.9 0.2 0.042 13.9 0.2 2.3 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit PPR_3 PF13812.1 EMD64186.1 - 0.17 12.2 1.9 5.9 7.4 0.0 4.5 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Sel1 PF08238.7 EMD64186.1 - 0.86 10.3 4.2 16 6.3 0.2 3.1 2 0 0 2 2 2 0 Sel1 repeat TPR_14 PF13428.1 EMD64186.1 - 1.8 9.4 13.5 15 6.5 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64186.1 - 2.6 8.8 9.8 11 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMD64186.1 - 9.4 6.6 10.5 1.6 9.0 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Zn_clus PF00172.13 EMD64187.1 - 8e-06 25.6 8.7 1.6e-05 24.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-Q PF13094.1 EMD64188.1 - 6.2e-37 127.0 4.5 6.2e-37 127.0 3.1 2.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EMD64188.1 - 0.47 10.3 15.5 0.17 11.7 6.8 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EMD64188.1 - 0.78 9.5 5.3 6.2 6.6 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.1 EMD64188.1 - 1.1 8.5 9.1 0.18 11.1 2.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus BRE1 PF08647.6 EMD64188.1 - 1.2 9.1 7.2 0.54 10.2 1.0 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Glyco_hydro_35 PF01301.14 EMD64189.1 - 0.13 11.5 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HhH-GPD PF00730.20 EMD64190.1 - 7.9e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMD64190.1 - 0.02 14.5 0.0 0.063 13.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Abhydrolase_2 PF02230.11 EMD64191.1 - 4.6e-60 202.7 0.1 5.1e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMD64191.1 - 4.6e-11 42.6 0.0 7.5e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD64191.1 - 3e-06 26.6 1.6 0.00015 21.0 0.1 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMD64191.1 - 3.9e-05 23.3 0.2 0.16 11.5 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD64191.1 - 5.5e-05 23.1 0.0 0.012 15.5 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EMD64191.1 - 7.3e-05 22.3 0.0 0.00062 19.2 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EMD64191.1 - 0.00011 21.5 0.2 0.00021 20.6 0.1 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 EMD64191.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EMD64191.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydro_lipase PF04083.11 EMD64191.1 - 0.046 13.0 0.0 2.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Chitin_bind_1 PF00187.14 EMD64192.1 - 7.3e-17 61.0 70.3 2.9e-11 43.1 10.2 4.6 3 2 0 3 3 3 3 Chitin recognition protein HCV_NS4b PF01001.14 EMD64193.1 - 0.019 14.3 3.9 0.023 14.0 2.7 1.0 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b DUF1469 PF07332.6 EMD64193.1 - 3.8 7.2 10.2 5.7 6.6 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) adh_short PF00106.20 EMD64194.1 - 1.5e-21 77.0 0.1 5.8e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD64194.1 - 1.5e-16 60.9 0.1 1.9e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD64194.1 - 9.4e-06 25.4 0.1 1.9e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EMD64194.1 - 4.2e-05 23.6 0.4 9.4e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMD64194.1 - 5.5e-05 22.1 0.8 0.0001 21.2 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD64194.1 - 0.0047 16.9 0.1 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Pyr_redox PF00070.22 EMD64194.1 - 0.0084 16.5 1.0 0.62 10.5 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMD64194.1 - 0.019 14.6 0.8 0.05 13.2 0.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMD64194.1 - 0.024 14.0 0.3 0.086 12.2 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EMD64194.1 - 0.026 14.7 0.5 0.054 13.7 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N PF00107.21 EMD64194.1 - 0.056 12.9 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 EMD64194.1 - 0.099 11.7 0.1 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) BicD PF09730.4 EMD64195.1 - 0.00054 18.4 1.4 0.00078 17.9 1.0 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Transcript_VP30 PF11507.3 EMD64195.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Microtub_assoc PF07989.6 EMD64195.1 - 0.9 9.4 5.6 7.9 6.3 0.1 3.0 2 1 1 3 3 3 0 Microtubule associated DUF972 PF06156.8 EMD64195.1 - 6.6 7.1 7.0 29 5.0 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HSP70 PF00012.15 EMD64196.1 - 1.1e-12 46.6 0.0 2.3e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD64196.1 - 0.024 13.2 0.0 0.047 12.2 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein DUF3798 PF12683.2 EMD64196.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Zn_clus PF00172.13 EMD64200.1 - 7.9e-08 32.0 8.0 1.3e-07 31.3 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos_2 PF12850.2 EMD64201.1 - 1.5e-11 44.4 0.0 3.5e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMD64201.1 - 3.5e-10 39.6 2.6 5.1e-09 35.8 1.8 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HLH PF00010.21 EMD64202.1 - 2.3e-14 52.7 1.8 6.9e-14 51.2 0.2 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 EMD64202.1 - 0.11 11.9 0.8 0.65 9.5 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Bromodomain PF00439.20 EMD64203.1 - 6.5e-27 93.2 0.0 1.3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DAP_B PF07930.7 EMD64203.1 - 0.11 12.2 1.3 1 9.1 0.5 2.3 2 0 0 2 2 2 0 D-aminopeptidase, domain B SlyX PF04102.7 EMD64204.1 - 0.0023 18.2 0.1 0.0052 17.1 0.1 1.5 1 0 0 1 1 1 1 SlyX CENP-Q PF13094.1 EMD64204.1 - 0.0039 17.2 0.6 0.0048 16.9 0.4 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EMD64204.1 - 0.0063 16.2 0.5 0.0096 15.7 0.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Sugarporin_N PF11471.3 EMD64204.1 - 0.046 13.3 1.0 0.087 12.4 0.7 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Striatin PF08232.7 EMD64204.1 - 0.061 13.6 0.6 0.086 13.1 0.4 1.2 1 0 0 1 1 1 0 Striatin family DUF4407 PF14362.1 EMD64204.1 - 0.13 11.2 2.7 0.14 11.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MerR-DNA-bind PF09278.6 EMD64204.1 - 0.13 12.7 1.2 0.19 12.1 0.9 1.4 1 0 0 1 1 1 0 MerR, DNA binding DUF3987 PF13148.1 EMD64204.1 - 0.42 9.1 3.4 0.54 8.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP_transf PF09830.4 EMD64205.1 - 1.8e-15 56.4 0.0 3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Peptidase_M14 PF00246.19 EMD64206.1 - 1.8e-77 260.6 0.2 2.3e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EMD64206.1 - 0.038 13.6 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Carboxypeptidase activation peptide HTH_Tnp_Tc5 PF03221.11 EMD64207.1 - 1.1e-11 44.3 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD64207.1 - 2.6e-06 26.8 0.2 4.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD64207.1 - 0.0013 18.8 0.3 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMD64207.1 - 0.034 14.1 0.1 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD64207.1 - 0.05 13.2 0.6 0.28 10.8 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Ribosomal_S13_N PF08069.7 EMD64207.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain HTH_Tnp_1 PF01527.15 EMD64207.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Transposase Cdc6_C PF09079.6 EMD64207.1 - 0.12 12.1 0.0 5.7 6.7 0.0 2.2 1 1 1 2 2 2 0 CDC6, C terminal HTH_36 PF13730.1 EMD64207.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 2 1 1 3 3 3 0 Helix-turn-helix domain Ferric_reduct PF01794.14 EMD64208.1 - 2.7e-16 59.8 19.5 2.7e-16 59.8 13.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMD64208.1 - 8.9e-16 57.6 0.0 2.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD64208.1 - 1.8e-13 50.6 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EMD64208.1 - 0.0012 19.4 0.0 0.042 14.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF872 PF05915.7 EMD64208.1 - 0.0034 17.2 0.7 0.015 15.1 0.5 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) DUF3265 PF11665.3 EMD64208.1 - 1.8 8.4 7.8 25 4.8 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Ctr PF04145.10 EMD64209.1 - 1.8e-27 96.1 5.8 3.6e-27 95.1 4.0 1.4 1 1 0 1 1 1 1 Ctr copper transporter family DUF2721 PF11026.3 EMD64209.1 - 0.73 9.4 7.8 5.5 6.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) SMC_N PF02463.14 EMD64210.1 - 2.2e-23 82.6 0.0 5.4e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMD64210.1 - 4.7e-14 53.2 17.6 4.7e-14 53.2 12.2 5.4 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EMD64210.1 - 3.8e-05 23.8 1.0 0.00045 20.2 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMD64210.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD64210.1 - 0.0046 16.3 0.0 0.027 13.8 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMD64210.1 - 0.025 14.8 0.6 0.14 12.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMD64210.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMD64210.1 - 4 7.5 8.6 1.9 8.6 0.0 4.0 4 1 1 5 5 5 0 AAA domain Lectin_N PF03954.9 EMD64210.1 - 4.4 6.7 20.5 7.3 5.9 0.2 4.9 4 1 0 4 4 4 0 Hepatic lectin, N-terminal domain Reo_sigmaC PF04582.7 EMD64210.1 - 6.9 5.7 17.6 0.78 8.8 0.8 3.7 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Pkinase PF00069.20 EMD64211.1 - 1.8e-55 187.9 0.1 1.3e-54 185.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64211.1 - 5.3e-29 101.0 0.2 1.5e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMD64211.1 - 9.3e-06 26.0 0.4 3.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMD64211.1 - 0.00022 20.3 0.2 0.0017 17.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD64211.1 - 0.00091 19.0 0.5 0.14 11.8 0.0 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD64211.1 - 0.031 13.3 0.0 0.09 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 EMD64212.1 - 1.2e-08 34.5 9.7 2.1e-08 33.8 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD64212.1 - 1.1e-07 31.9 5.2 1.7e-07 31.2 3.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMD64212.1 - 6.1e-07 29.1 3.0 1.1e-06 28.3 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMD64212.1 - 9.3e-06 25.2 7.5 1.6e-05 24.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD64212.1 - 1.3e-05 25.1 5.0 6.9e-05 22.7 3.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD64212.1 - 0.00015 21.4 2.2 0.00034 20.2 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMD64212.1 - 0.0002 21.0 10.1 0.00033 20.3 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD64212.1 - 0.0025 17.4 7.7 0.0043 16.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD64212.1 - 0.011 15.5 3.5 0.011 15.5 2.4 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMD64212.1 - 0.54 9.8 4.3 1 8.9 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EMD64212.1 - 2.5 8.1 7.1 4.7 7.2 5.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zinc-ribbons_6 PF07191.7 EMD64212.1 - 3 7.7 8.6 1.9 8.3 0.9 2.2 1 1 0 2 2 2 0 zinc-ribbons Lyase_1 PF00206.15 EMD64214.1 - 2.8e-113 378.2 0.0 4e-113 377.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EMD64214.1 - 4.4e-22 77.8 0.1 9.8e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Ank_2 PF12796.2 EMD64216.1 - 7.5e-21 74.2 1.3 9.8e-21 73.9 0.8 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD64216.1 - 3.1e-19 67.7 7.4 7.6e-08 31.8 0.4 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMD64216.1 - 5.4e-18 65.0 1.1 8.3e-13 48.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD64216.1 - 2.5e-17 62.5 6.2 2e-07 31.0 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64216.1 - 1.8e-12 46.2 2.5 5.7e-05 22.9 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF1843 PF08898.5 EMD64216.1 - 0.0043 17.0 1.0 0.29 11.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) RVP PF00077.15 EMD64216.1 - 0.044 13.6 0.0 0.94 9.4 0.0 2.2 1 1 1 2 2 2 0 Retroviral aspartyl protease DAO PF01266.19 EMD64217.1 - 2.3e-07 30.0 0.0 0.0094 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD64217.1 - 5.6e-06 25.4 0.0 9.6e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD64217.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD64217.1 - 3.6e-05 24.0 0.1 0.0021 18.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD64217.1 - 0.00018 21.4 0.1 0.00038 20.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD64217.1 - 0.00026 20.1 0.5 0.0034 16.4 0.4 2.4 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD64217.1 - 0.0024 16.4 0.1 0.037 12.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMD64217.1 - 0.004 17.2 0.1 0.017 15.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD64217.1 - 0.0045 16.1 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD64217.1 - 0.0079 15.9 2.5 3.6 7.3 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 EMD64217.1 - 0.12 11.2 0.1 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 EMD64218.1 - 2.5e-33 112.7 3.4 1.2e-13 50.3 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EMD64218.1 - 2.4e-07 29.2 0.1 0.0027 15.8 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_16 PF13191.1 EMD64218.1 - 7.6e-07 29.2 0.4 1.1e-05 25.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EMD64218.1 - 1.9e-06 27.6 0.0 4.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.4 EMD64218.1 - 0.00047 19.4 0.0 7.4 5.9 0.0 3.7 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature NB-ARC PF00931.17 EMD64218.1 - 0.00061 18.7 0.0 0.0017 17.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EMD64218.1 - 0.00068 19.7 0.1 0.0028 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Gmad1 PF10647.4 EMD64218.1 - 0.0052 16.2 2.2 0.01 15.2 1.5 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EMD64218.1 - 0.0063 16.1 0.1 31 4.3 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EMD64218.1 - 0.014 15.1 0.0 0.068 12.8 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A AAA PF00004.24 EMD64218.1 - 0.029 14.5 0.1 0.095 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Snf7 PF03357.16 EMD64218.1 - 0.049 13.0 0.7 0.12 11.7 0.5 1.6 1 0 0 1 1 1 0 Snf7 AAA_33 PF13671.1 EMD64218.1 - 0.061 13.1 0.0 0.3 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD64218.1 - 0.098 12.8 0.1 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EMD64218.1 - 0.12 13.2 0.1 0.43 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EMD64218.1 - 0.14 11.8 0.2 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 EMD64218.1 - 0.16 12.2 0.0 0.63 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 EMD64218.1 - 0.24 10.5 3.0 0.41 9.8 2.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HTH_Tnp_Tc5 PF03221.11 EMD64219.1 - 5.2e-07 29.3 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pes-10 PF07149.6 EMD64221.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Pes-10 Fungal_trans PF04082.13 EMD64222.1 - 1.6e-21 76.4 0.0 2.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64222.1 - 0.00064 19.5 8.9 0.0013 18.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YvfG PF09628.5 EMD64222.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 YvfG protein N2227 PF07942.7 EMD64223.1 - 3.6e-57 193.4 0.0 5.5e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 EMD64223.1 - 7.6e-06 26.3 0.0 5.5e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD64223.1 - 0.00023 21.5 0.0 0.00057 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD64223.1 - 0.00048 19.8 0.1 0.0014 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD64223.1 - 0.0023 18.4 0.1 0.018 15.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD64223.1 - 0.0056 16.2 0.2 0.034 13.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Sugar_tr PF00083.19 EMD64224.1 - 9.9e-102 340.8 27.3 1.1e-101 340.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD64224.1 - 4.1e-27 94.8 33.9 4.2e-24 84.9 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMD64224.1 - 9.2e-05 20.6 1.7 9.2e-05 20.6 1.2 2.4 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family SGL PF08450.7 EMD64225.1 - 7.5e-31 107.3 0.1 1.3e-30 106.6 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EMD64225.1 - 9.2e-06 25.5 0.0 3.1e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Arylesterase NHL PF01436.16 EMD64225.1 - 3.6e-05 23.5 5.0 0.19 11.7 0.0 4.0 5 0 0 5 5 5 2 NHL repeat Str_synth PF03088.11 EMD64225.1 - 0.0052 16.7 0.0 0.029 14.3 0.0 2.3 2 1 0 2 2 2 1 Strictosidine synthase DUF4050 PF13259.1 EMD64227.1 - 1.1e-36 125.4 0.2 1.5e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF1191 PF06697.7 EMD64227.1 - 0.2 10.4 2.3 0.3 9.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Peptidase_C2 PF00648.16 EMD64228.1 - 1.3e-60 204.9 1.1 4.6e-38 130.9 0.1 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease XhlA PF10779.4 EMD64228.1 - 0.066 13.1 3.7 0.15 11.9 2.5 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Sugar_tr PF00083.19 EMD64231.1 - 9.1e-71 238.7 21.6 1.1e-70 238.4 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD64231.1 - 3e-16 59.0 38.5 1.6e-11 43.5 11.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD64231.1 - 0.00078 17.9 11.4 0.00078 17.9 7.9 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein DDE_3 PF13358.1 EMD64232.1 - 1.8e-05 24.4 1.4 2.9e-05 23.8 0.9 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_35 PF01301.14 EMD64233.1 - 1.1e-79 268.1 2.2 3.3e-78 263.2 1.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EMD64233.1 - 2.6e-60 202.8 8.0 4.6e-60 202.0 5.6 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EMD64233.1 - 9.3e-44 148.2 16.4 2.2e-23 82.6 1.7 4.3 5 1 0 5 5 5 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EMD64233.1 - 9.4e-27 92.2 0.0 2.1e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Sel1 PF08238.7 EMD64234.1 - 1.7e-35 120.6 37.2 9e-07 29.3 0.3 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 EMD64234.1 - 0.11 12.9 13.2 5.2 7.7 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64234.1 - 0.52 11.0 9.4 0.4 11.4 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat CBP4 PF07960.6 EMD64235.1 - 1.1e-33 115.5 1.1 1.2e-33 115.5 0.8 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 EMD64235.1 - 0.0084 15.8 0.1 0.019 14.6 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4574) CBFB_NFYA PF02045.10 EMD64235.1 - 9 6.9 8.9 2.9 8.4 4.1 1.7 1 1 1 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ERCC4 PF02732.10 EMD64236.1 - 8.6e-27 93.6 0.0 4.5e-26 91.3 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain eIF-1a PF01176.14 EMD64237.1 - 2.2e-28 97.4 0.1 3.1e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EMD64237.1 - 0.0059 16.6 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_r2 PF04542.9 EMD64238.1 - 0.025 14.1 0.4 0.055 13.0 0.3 1.6 1 0 0 1 1 1 0 Sigma-70 region 2 HRXXH PF13933.1 EMD64239.1 - 0.023 14.1 0.6 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase family MFS_1 PF07690.11 EMD64241.1 - 5.3e-41 140.4 25.7 5.3e-41 140.4 17.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64241.1 - 6.9e-14 51.2 19.3 1.2e-13 50.5 13.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EMD64241.1 - 0.05 11.6 4.4 0.47 8.4 2.5 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3390 PF11870.3 EMD64241.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF1228 PF06779.9 EMD64241.1 - 0.43 10.6 0.1 0.43 10.6 0.1 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EMD64242.1 - 8.2e-40 136.5 41.6 1.7e-39 135.5 27.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64242.1 - 4.5e-14 51.8 8.4 4.5e-14 51.8 5.8 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMD64242.1 - 2.3e-12 45.9 12.8 3.5e-12 45.3 8.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIG-Y PF15159.1 EMD64242.1 - 0.0042 17.2 2.0 0.019 15.1 0.4 2.9 3 0 0 3 3 3 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y F-box-like PF12937.2 EMD64243.1 - 0.00025 20.6 0.1 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD64243.1 - 0.0084 15.7 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain HflK_N PF12221.3 EMD64243.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Aminotran_1_2 PF00155.16 EMD64244.1 - 3.1e-37 128.3 0.0 4.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4350 PF14258.1 EMD64244.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Beta_elim_lyase PF01212.16 EMD64244.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase RPN7 PF10602.4 EMD64245.1 - 1.2e-54 184.4 1.2 1.8e-54 183.8 0.8 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EMD64245.1 - 1.2e-14 54.4 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 EMD64245.1 - 0.02 14.6 0.3 0.063 13.0 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 EMD64246.1 - 2.3e-61 207.5 0.0 1.2e-42 145.9 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EMD64246.1 - 8.8e-11 42.1 0.0 2.9e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD64246.1 - 1.1e-08 35.6 0.0 2.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD64246.1 - 1.4e-06 28.0 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD64246.1 - 1.7e-06 28.4 0.0 9.4e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD64246.1 - 8.4e-06 25.4 0.0 3.5e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DDRGK PF09756.4 EMD64246.1 - 0.00044 19.7 1.1 0.00044 19.7 0.8 2.2 2 0 0 2 2 2 1 DDRGK domain Raftlin PF15250.1 EMD64246.1 - 0.0026 16.3 1.3 0.0097 14.4 0.1 1.9 2 0 0 2 2 2 1 Raftlin Methyltransf_25 PF13649.1 EMD64246.1 - 0.0028 17.9 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMD64246.1 - 0.021 13.7 0.0 0.083 11.8 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EMD64246.1 - 0.077 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PEX11 PF05648.9 EMD64247.1 - 1.3e-71 240.4 0.4 1.5e-71 240.2 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GET2 PF08690.5 EMD64247.1 - 0.04 13.1 0.1 0.15 11.3 0.0 1.7 1 1 1 2 2 2 0 GET complex subunit GET2 Sugar_tr PF00083.19 EMD64249.1 - 3.1e-25 88.6 28.2 4.5e-17 61.7 7.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMD64249.1 - 3.3e-15 55.6 42.3 2.2e-11 43.0 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 EMD64249.1 - 0.34 10.2 1.9 0.61 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) HN PF00423.14 EMD64250.1 - 0.066 11.4 0.0 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase DUF3377 PF11857.3 EMD64251.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.1 EMD64251.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.13 EMD64251.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.1 EMD64251.1 - 0.035 14.5 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YtkA PF13115.1 EMD64251.1 - 0.064 13.6 0.2 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 YtkA-like PAG PF15347.1 EMD64251.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DUF912 PF06024.7 EMD64251.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HECT PF00632.20 EMD64252.1 - 1.3e-86 290.6 0.0 4e-86 289.0 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 EMD64252.1 - 0.0084 14.4 3.9 1.2 7.3 0.0 3.0 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 EMD64252.1 - 0.016 15.7 0.0 2.4 8.7 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EMD64252.1 - 0.034 14.2 0.7 14 6.0 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat CTP_transf_2 PF01467.21 EMD64254.1 - 2e-24 86.4 0.0 2.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Cellulase PF00150.13 EMD64255.1 - 1.4e-15 57.2 6.4 8.2e-15 54.7 4.5 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ETRAMP PF09716.5 EMD64255.1 - 0.023 14.6 0.0 0.091 12.7 0.0 2.0 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.1 EMD64255.1 - 0.27 11.2 0.2 0.51 10.4 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal OapA_N PF08525.6 EMD64255.1 - 2.7 7.8 5.1 4.5 7.1 3.5 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Smr PF01713.16 EMD64257.1 - 6e-11 42.3 0.1 1.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EMD64257.1 - 8.5e-07 28.8 2.9 2.1e-06 27.6 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) YajC PF02699.10 EMD64258.1 - 0.025 14.2 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit PepSY_TM PF03929.11 EMD64258.1 - 0.041 14.2 0.5 0.75 10.3 0.4 2.1 1 1 0 1 1 1 0 PepSY-associated TM helix DUF3481 PF11980.3 EMD64258.1 - 0.099 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) EphA2_TM PF14575.1 EMD64258.1 - 0.19 12.1 0.4 0.26 11.7 0.3 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 EMD64258.1 - 1 9.9 7.3 3.1 8.3 5.1 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red F-box-like PF12937.2 EMD64259.1 - 1.9e-08 33.8 0.1 3.4e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD64259.1 - 0.0083 15.7 0.8 0.0083 15.7 0.5 2.5 2 1 0 2 2 2 1 F-box domain zf-CCHC PF00098.18 EMD64260.1 - 0.00034 20.3 3.5 0.00034 20.3 2.4 3.0 3 0 0 3 3 3 1 Zinc knuckle Zn_Tnp_IS91 PF14319.1 EMD64260.1 - 0.4 10.2 8.0 0.33 10.4 3.9 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain HypA PF01155.14 EMD64260.1 - 2.3 7.9 7.9 1.5 8.4 3.5 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Abhydrolase_6 PF12697.2 EMD64261.1 - 5.4e-07 29.7 0.4 3.3e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD64261.1 - 9.5e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD64261.1 - 0.00034 20.3 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M19 PF01244.16 EMD64261.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF1100 PF06500.6 EMD64262.1 - 1.1e-13 50.6 0.0 1.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 EMD64262.1 - 1.3e-10 41.5 0.2 2e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD64262.1 - 2e-07 30.8 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMD64262.1 - 2.2e-05 24.0 0.2 6.5e-05 22.4 0.0 1.8 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMD64262.1 - 0.0004 19.6 0.1 0.001 18.3 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EMD64262.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EMD64262.1 - 0.033 13.6 0.2 0.13 11.6 0.1 1.9 1 1 0 1 1 1 0 Putative esterase D5_N PF08706.6 EMD64262.1 - 0.05 13.6 0.4 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 D5 N terminal like DLH PF01738.13 EMD64262.1 - 0.08 12.2 0.0 0.39 9.9 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2171 PF09939.4 EMD64262.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) zf-nanos PF05741.8 EMD64263.1 - 0.11 12.4 1.6 0.65 10.0 1.1 2.2 1 1 0 1 1 1 0 Nanos RNA binding domain DNA_pol_A_exo1 PF01612.15 EMD64264.1 - 3.2e-05 23.4 0.1 0.00015 21.3 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease RNase_T PF00929.19 EMD64264.1 - 0.0065 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease PTR2 PF00854.16 EMD64265.1 - 1e-47 162.7 10.3 1e-47 162.7 7.1 2.1 2 1 0 2 2 2 1 POT family Pyridox_oxidase PF01243.15 EMD64266.1 - 0.00065 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3364 PF11844.3 EMD64266.1 - 0.14 12.1 1.2 0.32 11.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Peptidase_M20 PF01546.23 EMD64267.1 - 3.8e-24 85.2 0.0 8.5e-24 84.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EMD64267.1 - 8e-16 57.2 0.8 0.00099 18.9 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 EMD64267.1 - 1.2e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EMD64267.1 - 0.19 10.4 0.0 0.46 9.2 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase RAP1 PF07218.6 EMD64268.1 - 5 5.1 19.9 11 3.9 13.8 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_3 PF01494.14 EMD64269.1 - 1.8e-18 66.7 0.0 5.4e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD64269.1 - 1.4e-09 37.3 0.1 5.8e-05 22.1 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD64269.1 - 4.5e-05 23.3 0.0 0.0002 21.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMD64269.1 - 0.015 13.9 0.3 1.4 7.4 0.0 2.1 1 1 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EMD64269.1 - 0.023 13.6 0.1 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMD64269.1 - 0.023 15.0 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EMD64270.1 - 5.3e-16 58.9 0.5 5.3e-16 58.9 0.4 2.2 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EMD64270.1 - 1.9e-09 37.3 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD64270.1 - 2.8e-08 33.9 0.1 4.3e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMD64270.1 - 2.9e-07 30.3 0.5 5.8e-07 29.3 0.2 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMD64270.1 - 1.9e-05 24.5 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMD64270.1 - 0.021 14.0 0.1 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.2 EMD64271.1 - 9e-50 166.9 0.4 2.2e-14 53.5 0.0 8.1 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMD64271.1 - 6.6e-38 126.6 14.4 1.4e-05 24.6 0.0 13.6 15 0 0 15 15 15 7 Ankyrin repeat Ank_4 PF13637.1 EMD64271.1 - 3.6e-37 126.0 3.4 4.6e-07 30.1 0.0 12.0 11 2 2 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD64271.1 - 3.7e-33 112.7 7.4 4.3e-05 23.6 0.0 11.0 9 3 2 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64271.1 - 7.2e-29 96.9 10.8 0.0082 16.2 0.0 14.0 15 1 0 15 15 15 5 Ankyrin repeat gag-asp_proteas PF13975.1 EMD64271.1 - 0.0095 15.7 0.1 0.073 12.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EMD64271.1 - 0.014 15.3 0.0 0.071 13.0 0.0 2.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RCC1_2 PF13540.1 EMD64272.1 - 0.00017 21.1 10.9 0.0039 16.7 0.0 3.4 4 1 1 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EMD64272.1 - 0.00066 19.8 6.1 0.64 10.2 0.0 4.2 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Peptidase_A22B PF04258.8 EMD64274.1 - 3.7e-54 184.1 0.0 1.3e-53 182.4 0.0 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EMD64274.1 - 3.5e-05 23.0 1.5 3.5e-05 23.0 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) RXT2_N PF08595.6 EMD64274.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF3829 PF12889.2 EMD64275.1 - 0.033 13.3 2.9 0.56 9.3 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Baculo_PEP_C PF04513.7 EMD64275.1 - 0.39 10.5 3.6 2.1 8.1 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.4 EMD64275.1 - 0.43 10.5 4.2 8.8 6.3 2.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Atg14 PF10186.4 EMD64275.1 - 1.3 7.9 8.5 0.56 9.1 4.6 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EMD64275.1 - 1.6 9.1 10.3 10 6.5 1.6 3.6 4 0 0 4 4 4 0 Syntaxin 6, N-terminal PRKCSH-like PF12999.2 EMD64275.1 - 4.9 6.7 6.7 1.1 8.8 0.1 2.2 1 1 1 2 2 2 0 Glucosidase II beta subunit-like NACHT PF05729.7 EMD64276.1 - 2.8e-13 49.8 0.1 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMD64276.1 - 0.00016 21.8 0.0 0.00033 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD64276.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EMD64276.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EMD64276.1 - 0.047 12.6 0.6 0.31 9.9 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.4 EMD64276.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EMD64276.1 - 0.14 12.1 0.0 0.77 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EMD64277.1 - 0.00016 21.9 0.0 0.00018 21.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD64277.1 - 0.0028 17.3 0.1 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMD64277.1 - 0.011 16.2 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD64277.1 - 0.036 14.3 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ADH_N PF08240.7 EMD64278.1 - 3.9e-18 65.2 0.2 4.5e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EMD64278.1 - 1.4e-06 27.7 1.2 1.6e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EMD64279.1 - 4.9e-08 32.5 0.1 7.8e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EMD64279.1 - 0.0069 14.9 0.5 0.038 12.4 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Pro_isomerase PF00160.16 EMD64280.1 - 6.9e-53 179.0 0.0 8e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2HC5 PF06221.8 EMD64281.1 - 6.6e-23 80.2 6.3 1.1e-22 79.4 4.4 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type KdpC PF02669.10 EMD64281.1 - 0.081 12.6 0.8 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain MBOAT_2 PF13813.1 EMD64284.1 - 8.9e-16 57.7 5.0 8.9e-16 57.7 3.5 2.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family PTCB-BRCT PF12738.2 EMD64285.1 - 3.8e-14 52.2 0.0 7.8e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EMD64285.1 - 5.6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EMD64285.1 - 0.00019 21.4 0.0 0.00061 19.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EMD64285.1 - 0.00035 20.2 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) Spt20 PF12090.3 EMD64285.1 - 0.0015 17.8 0.7 0.0029 17.0 0.5 1.5 1 0 0 1 1 1 1 Spt20 family DUF1297 PF06973.7 EMD64285.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Hid1 PF12722.2 EMD64285.1 - 9.8 3.7 10.1 14 3.1 7.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_63 PF03200.11 EMD64287.1 - 6.6e-06 24.2 4.2 8.9e-05 20.5 0.3 2.6 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Mob1_phocein PF03637.12 EMD64288.1 - 7.1e-72 240.7 0.0 8.5e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_45 PF02015.11 EMD64290.1 - 1.1e-63 214.9 15.4 1.4e-63 214.6 10.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF1757 PF08560.5 EMD64291.1 - 1.5e-06 27.9 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Gly-zipper_OmpA PF13436.1 EMD64291.1 - 0.044 13.4 9.6 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_98C PF08307.6 EMD64291.1 - 0.046 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain DUF543 PF04418.7 EMD64291.1 - 0.38 10.7 8.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF2537 PF10801.3 EMD64291.1 - 3.3 7.8 6.8 2.3 8.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) HCV_core PF01542.13 EMD64292.1 - 7.8 6.9 8.4 21 5.5 2.6 2.2 1 1 1 2 2 2 0 Hepatitis C virus core protein PIR PF00399.14 EMD64293.1 - 2.1e-15 55.4 43.2 0.0025 17.1 1.2 5.9 4 1 1 5 5 5 5 Yeast PIR protein repeat Mt_ATP-synt_D PF05873.7 EMD64294.1 - 2.3e-19 69.6 2.6 2.8e-19 69.3 1.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CCDC155 PF14662.1 EMD64294.1 - 0.0079 15.8 7.1 0.21 11.1 1.4 2.2 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 Dor1 PF04124.7 EMD64294.1 - 0.037 12.4 2.0 0.047 12.1 1.4 1.2 1 0 0 1 1 1 0 Dor1-like family T2SM_b PF10741.4 EMD64294.1 - 0.044 13.4 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b TPR_MLP1_2 PF07926.7 EMD64294.1 - 0.048 13.4 4.1 0.19 11.4 2.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein E3_UbLigase_R4 PF13764.1 EMD64294.1 - 0.069 11.0 0.4 0.081 10.8 0.3 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF2408 PF10303.4 EMD64294.1 - 0.074 13.1 1.3 0.11 12.6 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF148 PF02520.12 EMD64294.1 - 0.16 11.7 8.6 0.12 12.2 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Fib_alpha PF08702.5 EMD64294.1 - 0.23 11.5 2.7 0.3 11.1 0.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 EMD64294.1 - 0.48 10.6 4.6 0.41 10.8 1.6 1.8 1 1 1 2 2 2 0 Syntaxin Spectrin PF00435.16 EMD64294.1 - 0.5 10.6 5.6 2 8.7 1.1 2.5 1 1 2 3 3 3 0 Spectrin repeat BLOC1_2 PF10046.4 EMD64294.1 - 1.9 8.6 5.7 0.43 10.7 1.1 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EMD64294.1 - 2 7.9 5.6 5.1 6.6 2.7 1.9 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EMD64294.1 - 6.1 6.6 8.1 17 5.2 2.2 2.4 1 1 0 2 2 2 0 Tropomyosin like Arf PF00025.16 EMD64295.1 - 1.3e-63 213.3 0.0 1.4e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMD64295.1 - 8.6e-12 44.4 0.1 3.7e-08 32.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMD64295.1 - 2.3e-08 33.4 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMD64295.1 - 3.3e-07 29.8 0.0 4.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EMD64295.1 - 3.9e-07 30.0 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD64295.1 - 1.2e-06 28.9 0.0 1.6e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EMD64295.1 - 4.3e-06 26.0 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD64295.1 - 0.0023 17.3 0.1 0.081 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EMD64295.1 - 0.052 12.9 0.3 5.7 6.3 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EMD64295.1 - 0.064 12.7 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nup35_RRM PF05172.8 EMD64296.1 - 0.037 13.7 0.1 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EMD64296.1 - 0.04 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64296.1 - 0.18 11.8 0.0 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.12 EMD64297.1 - 3.8e-26 91.2 1.8 8.7e-26 90.0 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EMD64297.1 - 0.0002 20.9 1.1 0.00032 20.2 0.2 1.9 2 0 0 2 2 2 1 KOW motif Med3 PF11593.3 EMD64297.1 - 0.053 12.7 1.0 0.081 12.1 0.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAC PF01849.13 EMD64298.1 - 9.5e-25 85.8 0.0 6.2e-24 83.2 0.0 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EMD64298.1 - 0.0075 16.0 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 EMD64298.1 - 0.093 10.7 16.4 0.0049 14.9 5.8 1.9 2 0 0 2 2 2 0 CDC45-like protein DTHCT PF08070.6 EMD64298.1 - 0.28 11.8 9.6 3.8 8.2 3.7 2.4 2 1 0 2 2 2 0 DTHCT (NUC029) region Myc_N PF01056.13 EMD64298.1 - 1.1 8.3 17.2 0.52 9.4 5.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region SelP_N PF04592.9 EMD64298.1 - 4.8 6.4 13.1 0.22 10.8 5.1 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2946 PF11162.3 EMD64298.1 - 6.5 6.9 8.2 11 6.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TauD PF02668.11 EMD64300.1 - 6.9e-20 71.8 0.0 1.9e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3144 PF11342.3 EMD64300.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) Zn_clus PF00172.13 EMD64301.1 - 0.004 17.0 5.1 0.0083 16.0 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.4 EMD64302.1 - 1.2e-32 111.8 0.0 2.9e-32 110.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.20 EMD64302.1 - 2.8e-15 56.6 1.3 3.8e-14 52.9 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD64302.1 - 1.1e-05 25.1 1.5 1.5e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 KR domain LNS2 PF08235.8 EMD64302.1 - 0.054 13.0 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Polysacc_synt_2 PF02719.10 EMD64302.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LSM PF01423.17 EMD64303.1 - 2.4e-13 49.4 0.0 3.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD64303.1 - 0.055 13.3 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Ataxin 2 SM domain Cellulase PF00150.13 EMD64306.1 - 9.8e-16 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMD64306.1 - 0.00071 19.9 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EMD64306.1 - 0.016 14.1 0.0 0.029 13.2 0.0 1.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain HLH PF00010.21 EMD64308.1 - 1.1e-07 31.4 0.0 2.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_S64 PF08192.6 EMD64308.1 - 0.15 10.3 7.6 0.22 9.7 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 EMD64308.1 - 0.66 8.1 11.9 0.32 9.2 6.6 1.6 2 0 0 2 2 2 0 Transmembrane protein Cnl2_NKP2 PF09447.5 EMD64310.1 - 8.9e-24 82.9 0.8 1.9e-23 81.9 0.1 1.9 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Peripla_BP_3 PF13377.1 EMD64310.1 - 0.001 19.0 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein-like domain TPR_MLP1_2 PF07926.7 EMD64310.1 - 0.028 14.1 2.5 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Adenylsucc_synt PF00709.16 EMD64310.1 - 0.044 12.4 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase V_ATPase_I PF01496.14 EMD64310.1 - 0.046 11.5 0.6 0.054 11.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DMPK_coil PF08826.5 EMD64310.1 - 0.05 13.4 3.7 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like COG2 PF06148.6 EMD64310.1 - 0.055 13.3 0.3 0.13 12.1 0.2 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 EMD64310.1 - 0.061 13.7 2.6 0.14 12.5 1.0 2.2 2 1 0 2 2 1 0 Syntaxin 6, N-terminal CENP-H PF05837.7 EMD64310.1 - 0.066 13.3 0.4 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF327 PF03885.8 EMD64310.1 - 0.12 12.1 0.2 0.86 9.4 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DUF4407 PF14362.1 EMD64310.1 - 0.15 10.9 0.9 0.2 10.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.8 EMD64310.1 - 0.32 11.3 0.2 0.32 11.3 0.1 2.7 3 1 1 4 4 4 0 Histidine kinase IncA PF04156.9 EMD64310.1 - 0.33 10.5 8.0 0.51 9.9 0.5 2.1 1 1 1 2 2 2 0 IncA protein FlxA PF14282.1 EMD64310.1 - 0.39 10.6 3.7 0.37 10.7 1.3 1.8 1 1 1 2 2 2 0 FlxA-like protein KfrA_N PF11740.3 EMD64310.1 - 0.48 10.8 6.1 3.9 7.9 0.7 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.10 EMD64310.1 - 0.54 9.7 0.1 0.54 9.7 0.0 2.4 2 1 0 2 2 2 0 Septum formation initiator EzrA PF06160.7 EMD64310.1 - 0.98 7.5 5.3 26 2.7 3.9 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA MRG PF05712.8 EMD64311.1 - 4.5e-51 172.5 0.1 6.3e-51 172.0 0.1 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EMD64311.1 - 4.6e-10 39.0 2.2 8.4e-10 38.2 1.5 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EMD64311.1 - 0.00081 19.0 1.3 0.0021 17.7 0.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DivIVA PF05103.8 EMD64311.1 - 0.43 10.6 4.2 0.29 11.1 1.4 1.8 2 0 0 2 2 2 0 DivIVA protein AAA_18 PF13238.1 EMD64312.1 - 1.6e-09 38.1 0.0 5.4e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD64312.1 - 4.3e-08 33.9 0.0 8.9e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMD64312.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EMD64312.1 - 0.023 14.5 0.0 0.084 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD64312.1 - 0.024 14.6 0.7 0.085 12.8 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EMD64312.1 - 0.025 14.4 0.0 0.047 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 EMD64312.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EMD64312.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EMD64312.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1741 PF08427.5 EMD64313.1 - 9.4e-82 274.0 0.0 1.6e-81 273.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF433 PF04255.9 EMD64313.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) IMS PF00817.15 EMD64316.1 - 2.5e-38 131.2 0.0 6.2e-38 129.9 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EMD64316.1 - 3.1e-10 40.0 0.1 1.4e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMD64316.1 - 0.0023 17.8 0.0 0.0062 16.5 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 EMD64316.1 - 0.027 14.6 0.0 0.4 10.8 0.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF1131 PF06572.7 EMD64316.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Pyridoxal_deC PF00282.14 EMD64317.1 - 3.4e-19 68.5 0.0 4.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMD64317.1 - 2.5e-06 26.4 0.0 5.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMD64317.1 - 0.00027 20.0 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L16 PF00252.13 EMD64318.1 - 9.1e-30 103.1 0.2 1.5e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 EMD64318.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family RFC1 PF08519.7 EMD64319.1 - 2.3e-60 202.8 0.7 6.3e-60 201.4 0.1 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EMD64319.1 - 4.9e-13 49.0 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EMD64319.1 - 1.6e-09 38.0 0.0 5.7e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EMD64319.1 - 2e-05 23.4 0.0 4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMD64319.1 - 0.00011 22.3 0.0 0.00058 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD64319.1 - 0.00018 22.2 0.0 0.00018 22.2 0.0 3.5 4 1 0 4 4 2 1 AAA domain AAA_16 PF13191.1 EMD64319.1 - 0.00032 20.7 0.6 0.0051 16.8 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 EMD64319.1 - 0.0019 17.8 0.3 0.0052 16.5 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EMD64319.1 - 0.0023 17.8 0.0 0.0073 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD64319.1 - 0.0049 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EMD64319.1 - 0.02 15.1 0.0 0.02 15.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain PTCB-BRCT PF12738.2 EMD64319.1 - 0.022 14.6 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain AAA_28 PF13521.1 EMD64319.1 - 0.025 14.5 3.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMD64319.1 - 0.029 14.2 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMD64319.1 - 0.094 12.3 0.0 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain 5_nucleotid_C PF02872.13 EMD64320.1 - 2.8e-34 118.3 0.6 6.4e-34 117.1 0.4 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMD64320.1 - 6.9e-11 41.9 0.6 3.5e-10 39.5 0.5 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EMD64320.1 - 0.0031 16.5 0.1 0.0054 15.7 0.1 1.3 1 0 0 1 1 1 1 YmdB-like protein Glyco_hydro_2_N PF02837.13 EMD64322.1 - 1.1e-35 122.6 0.0 1.3e-32 112.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMD64322.1 - 8.5e-32 110.2 0.0 4.3e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMD64322.1 - 1.9e-14 54.0 3.7 3.3e-14 53.2 1.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMD64322.1 - 0.00045 20.4 0.2 0.031 14.5 0.0 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cellulase-like PF12876.2 EMD64322.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like SNARE PF05739.14 EMD64323.1 - 0.0071 16.0 0.1 0.0099 15.5 0.1 1.2 1 0 0 1 1 1 1 SNARE domain DUF4349 PF14257.1 EMD64323.1 - 0.057 12.6 0.1 0.073 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DASH_Duo1 PF08651.5 EMD64323.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 ArfGap PF01412.13 EMD64324.1 - 8.6e-41 138.4 0.6 1.4e-40 137.6 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fzo_mitofusin PF04799.8 EMD64325.1 - 0.022 14.1 0.4 0.032 13.5 0.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region Ribosomal_60s PF00428.14 EMD64325.1 - 9.8 6.6 36.7 0.7 10.3 2.7 3.4 2 1 1 3 3 3 0 60s Acidic ribosomal protein SPOC PF07744.8 EMD64326.1 - 5.5e-17 62.3 0.0 1.2e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EMD64326.1 - 3.8e-16 59.1 0.1 7.5e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EMD64326.1 - 8.2e-09 35.0 11.7 1.5e-08 34.1 8.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EMD64326.1 - 0.13 12.4 4.1 0.58 10.4 2.9 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 EMD64326.1 - 0.77 9.1 6.6 1.3 8.3 4.6 1.4 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.21 EMD64328.1 - 7.2e-61 204.7 0.1 8.7e-61 204.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMD64328.1 - 3.4e-14 51.8 0.2 7e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EMD64328.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EMD64329.1 - 6.9e-15 54.7 8.0 2e-11 43.6 0.0 4.1 4 0 0 4 4 4 2 FF domain WW PF00397.21 EMD64329.1 - 4.4e-10 39.2 9.0 7.9e-09 35.2 3.1 2.6 2 0 0 2 2 2 2 WW domain NOA36 PF06524.7 EMD64329.1 - 0.5 9.5 5.7 1.3 8.2 4.0 1.6 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.11 EMD64330.1 - 6e-36 123.8 34.6 6e-36 123.8 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD64330.1 - 8.7e-12 44.0 0.9 8.7e-12 44.0 0.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NfeD PF01957.13 EMD64330.1 - 2.1 8.5 6.3 1.6 8.8 0.0 2.9 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding PAS PF00989.19 EMD64331.1 - 8.9e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EMD64331.1 - 0.0042 16.9 8.7 0.0084 15.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 EMD64331.1 - 0.041 14.2 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain Flavokinase PF01687.12 EMD64332.1 - 1.7e-38 131.3 0.0 2.9e-38 130.5 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase Aldo_ket_red PF00248.16 EMD64333.1 - 3.2e-20 72.1 0.0 4.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_1 PF00667.15 EMD64335.1 - 1e-59 201.6 0.0 2.4e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMD64335.1 - 1.4e-12 48.0 0.0 7e-12 45.8 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EMD64335.1 - 9.8e-07 28.8 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EMD64335.1 - 0.018 14.9 0.1 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 EMD64335.1 - 0.073 13.2 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyoxalase PF00903.20 EMD64337.1 - 6.1e-38 129.6 0.2 9.7e-19 67.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMD64337.1 - 1.4e-31 109.2 0.1 1.8e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMD64337.1 - 4.2e-18 65.3 0.0 6.4e-07 29.3 0.0 4.3 2 2 2 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMD64337.1 - 9.5e-07 28.8 0.0 0.04 13.8 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EMD64337.1 - 0.0083 15.8 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal MoaF PF10703.4 EMD64337.1 - 0.026 13.6 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F 2-Hacid_dh_C PF02826.14 EMD64338.1 - 8.4e-58 194.4 0.1 2.3e-57 193.0 0.0 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD64338.1 - 4.9e-37 126.3 0.4 8.8e-37 125.5 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EMD64338.1 - 0.029 14.6 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_C PF03720.10 EMD64338.1 - 0.078 13.1 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AIB PF15334.1 EMD64338.1 - 0.15 11.1 0.7 0.23 10.4 0.5 1.2 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein HutP PF09021.6 EMD64338.1 - 0.29 11.3 5.1 3.2 7.9 3.5 2.4 1 1 0 1 1 1 0 HutP DUF4470 PF14737.1 EMD64339.1 - 5.3e-22 77.4 0.0 9.5e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EMD64339.1 - 2.6e-06 27.1 9.4 6.9e-06 25.8 6.5 1.7 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EMD64339.1 - 0.021 14.1 1.3 0.055 12.7 0.9 1.7 1 0 0 1 1 1 0 Life-span regulatory factor NAD_binding_10 PF13460.1 EMD64340.1 - 9.8e-09 35.4 0.2 1.4e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EMD64340.1 - 2.3e-08 32.9 0.0 7.4e-08 31.2 0.0 1.8 1 1 1 2 2 2 1 HIM1 Semialdhyde_dh PF01118.19 EMD64340.1 - 0.00036 20.8 0.0 0.0011 19.2 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EMD64340.1 - 0.00052 19.0 0.0 0.12 11.2 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EMD64340.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MOSC PF03473.12 EMD64342.1 - 7e-21 74.0 0.0 1.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EMD64342.1 - 5.6e-12 45.2 2.3 1.4e-11 43.9 1.6 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.19 EMD64342.1 - 2.1e-05 24.5 0.0 6.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD64342.1 - 4.6e-05 23.9 0.0 0.0026 18.3 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMD64342.1 - 0.0084 16.0 0.0 0.87 9.4 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain 3-alpha PF03475.9 EMD64342.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 3-alpha domain GFA PF04828.9 EMD64347.1 - 5.7e-12 45.4 0.1 5.7e-12 45.4 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_3 PF07859.8 EMD64348.1 - 8.7e-28 97.3 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMD64348.1 - 1.4e-13 50.2 0.0 4e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) DUF3089 PF11288.3 EMD64348.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 EMD64348.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD64349.1 - 2.8e-23 82.9 0.5 3.5e-23 82.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD64349.1 - 1.6e-15 57.2 0.0 9.6e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD64349.1 - 6.5e-08 32.4 0.3 8.1e-08 32.1 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD64349.1 - 0.00041 20.1 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EMD64349.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Ndr family TrkH PF02386.11 EMD64350.1 - 3.6e-110 367.8 7.4 1e-107 359.8 2.6 2.1 2 0 0 2 2 2 2 Cation transport protein Tim17 PF02466.14 EMD64353.1 - 2.6e-33 114.8 5.0 2.9e-33 114.6 3.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dynamin_M PF01031.15 EMD64354.1 - 2.5e-22 79.0 0.8 7e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EMD64354.1 - 2.6e-07 30.6 0.0 1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EMD64354.1 - 0.0053 16.6 0.4 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Abhydrolase_3 PF07859.8 EMD64355.1 - 1.1e-15 57.8 0.2 4.6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gly_transf_sug PF04488.10 EMD64357.1 - 8.7e-09 35.7 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMD64357.1 - 0.0092 14.5 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EMD64357.1 - 0.039 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein GBV-C_env PF12786.2 EMD64358.1 - 0.012 14.0 0.1 0.014 13.8 0.0 1.0 1 0 0 1 1 1 0 GB virus C genotype envelope VHS PF00790.14 EMD64359.1 - 5.2e-41 139.5 0.0 5.2e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EMD64359.1 - 1.9e-18 66.1 4.4 4e-18 65.0 3.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EMD64359.1 - 0.0011 18.8 0.5 0.0023 17.8 0.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.15 EMD64359.1 - 0.0022 17.4 19.5 0.027 14.0 0.7 3.7 3 0 0 3 3 3 2 Ubiquitin interaction motif IBR PF01485.16 EMD64359.1 - 0.0047 16.7 2.4 0.011 15.5 1.6 1.6 1 0 0 1 1 1 1 IBR domain UCH PF00443.24 EMD64360.1 - 2.1e-55 187.7 0.0 3.9e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD64360.1 - 9.4e-22 77.7 0.0 2.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 EMD64360.1 - 0.0012 18.7 3.0 0.0065 16.4 0.1 2.8 3 0 0 3 3 3 1 USP8 dimerisation domain Rhodanese PF00581.15 EMD64360.1 - 0.016 15.5 0.0 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Arginosuc_synth PF00764.14 EMD64361.1 - 3.2e-150 500.4 0.0 3.7e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EMD64361.1 - 0.0089 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Ish1 PF10281.4 EMD64361.1 - 0.15 12.1 0.2 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF4234 PF14018.1 EMD64362.1 - 1.5 8.6 8.8 0.28 10.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) AgrB PF04647.10 EMD64362.1 - 3.2 6.7 10.5 0.42 9.6 0.9 2.5 2 1 0 2 2 2 0 Accessory gene regulator B VWA_3 PF13768.1 EMD64363.1 - 9.5e-28 96.8 0.0 1.7e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EMD64363.1 - 9.9e-20 70.4 0.1 1.9e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EMD64363.1 - 5.8e-13 49.3 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EMD64363.1 - 4.1e-10 38.9 0.1 9.5e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EMD64363.1 - 4.1e-08 33.1 0.0 7.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMD64363.1 - 7.1e-05 22.0 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ribosomal_60s PF00428.14 EMD64363.1 - 0.0016 18.8 0.1 0.0016 18.8 0.1 3.2 4 0 0 4 4 4 1 60s Acidic ribosomal protein DUF2201 PF09967.4 EMD64363.1 - 0.044 13.8 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 VWA-like domain (DUF2201) DUF21 PF01595.15 EMD64364.1 - 2e-32 111.9 0.3 3.2e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EMD64364.1 - 1.5e-06 27.9 0.2 0.0055 16.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain T4_Gp59_C PF08994.5 EMD64364.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Transket_pyr PF02779.19 EMD64365.1 - 1.5e-42 145.0 0.0 2.5e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMD64365.1 - 4.4e-33 113.8 0.2 1.1e-31 109.3 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain OsmC PF02566.14 EMD64366.1 - 2.1e-16 59.9 0.0 3.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein CPSase_L_D2 PF02786.12 EMD64367.1 - 1.2e-57 194.6 0.0 1.9e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMD64367.1 - 1.1e-32 112.1 0.0 2.4e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EMD64367.1 - 1.2e-25 89.7 0.0 4.3e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EMD64367.1 - 6.3e-17 61.8 0.1 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EMD64367.1 - 3.7e-13 48.9 3.7 6.2e-13 48.1 1.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EMD64367.1 - 1.2e-10 40.6 0.0 2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMD64367.1 - 4.3e-10 39.3 0.0 7.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMD64367.1 - 6.4e-07 28.8 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMD64367.1 - 4.9e-06 26.5 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMD64367.1 - 1.5e-05 24.5 0.3 1.5e-05 24.5 0.2 2.1 2 1 0 2 2 1 1 Biotin-lipoyl like RimK PF08443.6 EMD64367.1 - 8.3e-05 22.1 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF2118 PF09891.4 EMD64367.1 - 0.013 15.1 0.3 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.1 EMD64367.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD PF00529.15 EMD64367.1 - 0.022 14.0 0.2 0.047 12.9 0.1 1.6 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 EMD64367.1 - 0.037 13.1 0.4 0.23 10.5 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein Carboxyl_trans PF01039.17 EMD64368.1 - 2.2e-78 263.8 0.0 2.8e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain F_bP_aldolase PF01116.15 EMD64369.1 - 1.6e-73 247.3 0.2 1.8e-73 247.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EMD64369.1 - 0.0076 15.3 0.3 0.013 14.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotriesterase family CobS PF02654.10 EMD64369.1 - 0.037 13.6 0.3 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase Fungal_trans_2 PF11951.3 EMD64370.1 - 5.3e-08 31.8 0.1 7.1e-07 28.1 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64370.1 - 1e-07 31.7 10.7 1e-07 31.7 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IQ-like PF15157.1 EMD64370.1 - 0.032 14.4 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 IQ-like Endothelin PF00322.12 EMD64370.1 - 0.043 13.0 0.3 0.099 11.8 0.2 1.6 1 0 0 1 1 1 0 Endothelin family adh_short PF00106.20 EMD64371.1 - 1.9e-24 86.4 0.1 2.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD64371.1 - 3.4e-23 82.6 0.0 4.5e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD64371.1 - 1e-10 41.5 0.1 3.4e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMD64371.1 - 0.009 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMD64371.1 - 0.025 13.3 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EMD64372.1 - 1.7e-35 122.4 36.4 1.7e-35 122.4 25.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FGGY_N PF00370.16 EMD64372.1 - 0.069 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF2076 PF09849.4 EMD64373.1 - 0.0015 18.6 7.9 0.0015 18.6 5.5 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) BUD22 PF09073.5 EMD64374.1 - 1.6e-57 195.5 39.2 3e-57 194.6 27.2 1.4 1 1 0 1 1 1 1 BUD22 DUF1858 PF08984.6 EMD64374.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) bZIP_1 PF00170.16 EMD64375.1 - 0.0084 16.0 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor DDE_3 PF13358.1 EMD64376.1 - 2.1e-05 24.3 1.4 3.3e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AA_permease PF00324.16 EMD64377.1 - 7.8e-126 420.2 44.0 8.8e-126 420.0 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD64377.1 - 1.1e-38 132.8 51.9 1.4e-38 132.5 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EMD64377.1 - 0.0083 16.2 0.9 0.0083 16.2 0.6 4.4 5 0 0 5 5 5 1 PrgI family protein CHRD PF07452.7 EMD64378.1 - 1.9e-05 25.2 0.1 2.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 CHRD domain Colipase-like PF15083.1 EMD64380.1 - 0.087 12.7 0.7 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 Colipase-like Peptidase_S9 PF00326.16 EMD64381.1 - 6.8e-07 28.7 0.9 3.4e-05 23.1 0.5 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EMD64381.1 - 2.3e-06 27.0 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EMD64381.1 - 4.6e-06 26.4 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMD64381.1 - 0.0008 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EMD64381.1 - 0.011 15.1 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EMD64381.1 - 0.14 10.5 0.1 0.27 9.7 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_92 PF07971.7 EMD64382.1 - 3.7e-149 497.5 2.8 4.6e-149 497.2 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Myosin_tail_1 PF01576.14 EMD64384.1 - 9.7e-05 20.2 1.3 0.00012 19.9 0.9 1.0 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 EMD64384.1 - 0.005 16.6 0.6 1 9.1 0.1 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1664) HALZ PF02183.13 EMD64384.1 - 0.01 15.5 1.6 0.058 13.1 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EMD64384.1 - 0.021 14.6 0.3 4.6 7.2 0.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EMD64384.1 - 0.055 13.3 3.8 1.2 9.0 0.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_photolyase PF00875.13 EMD64384.1 - 0.059 13.1 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 DNA photolyase Kinetocho_Slk19 PF12709.2 EMD64384.1 - 0.067 13.2 2.3 0.083 12.9 0.1 2.2 3 0 0 3 3 3 0 Central kinetochore-associated bZIP_1 PF00170.16 EMD64384.1 - 0.12 12.3 1.5 0.2 11.6 0.3 1.8 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EMD64384.1 - 0.21 11.1 3.2 2.1 7.8 0.3 2.2 2 0 0 2 2 2 0 IncA protein THOC7 PF05615.8 EMD64384.1 - 0.35 11.1 4.0 7.2 6.8 0.0 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 APG6 PF04111.7 EMD64384.1 - 3.4 6.6 6.8 5.4 5.9 1.8 2.2 1 1 0 2 2 2 0 Autophagy protein Apg6 YrhK PF14145.1 EMD64385.1 - 5.4e-05 22.7 21.0 7.5e-05 22.3 0.7 4.8 4 1 0 4 4 4 3 YrhK-like protein Tetraspannin PF00335.15 EMD64385.1 - 0.66 9.2 12.6 0.84 8.8 0.3 3.1 2 1 1 3 3 3 0 Tetraspanin family DUF2636 PF11120.3 EMD64386.1 - 0.019 14.4 0.8 0.058 12.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Glyco_hydro_3 PF00933.16 EMD64387.1 - 1.9e-49 168.3 0.0 3.3e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD64387.1 - 3.5e-32 111.7 0.0 5.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Melibiase PF02065.13 EMD64388.1 - 1.2e-13 50.5 2.4 1.3e-09 37.2 0.0 2.9 2 1 0 2 2 2 2 Melibiase Glyco_hydro_2_N PF02837.13 EMD64388.1 - 5.6e-06 26.0 0.0 1.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EMD64388.1 - 0.00019 21.8 0.0 0.00045 20.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EMD64388.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain F-box PF00646.28 EMD64389.1 - 4.4e-08 32.5 0.0 9.2e-07 28.3 0.0 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EMD64389.1 - 2.3e-06 27.1 0.0 5.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EMD64389.1 - 0.034 14.5 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ferric_reduct PF01794.14 EMD64390.1 - 4.8e-20 71.9 9.8 1e-19 70.8 6.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD64390.1 - 3.6e-18 65.9 0.0 5.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD64390.1 - 1.4e-12 47.3 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMD64390.1 - 3e-05 24.5 0.0 0.00025 21.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ctr PF04145.10 EMD64391.1 - 5.3e-42 143.2 3.2 6.5e-42 142.9 2.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3040 PF11239.3 EMD64391.1 - 0.35 10.9 3.0 0.3 11.1 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) FliE PF02049.13 EMD64392.1 - 0.17 11.8 1.9 1.3 9.1 1.0 2.2 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Gln-synt_C PF00120.19 EMD64393.1 - 0.043 12.9 0.0 6.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Glutamine synthetase, catalytic domain Cutinase PF01083.17 EMD64394.1 - 1.1e-26 93.6 0.9 1.9e-26 92.8 0.6 1.4 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD64394.1 - 0.00047 19.6 2.2 0.0015 18.0 0.0 2.5 3 0 0 3 3 3 1 PE-PPE domain Abhydrolase_5 PF12695.2 EMD64394.1 - 0.0082 15.9 1.4 0.011 15.5 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0565 PF10561.4 EMD64394.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PGAP1 PF07819.8 EMD64394.1 - 0.046 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M23 PF01551.17 EMD64394.1 - 0.33 11.0 1.8 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 MFS_1 PF07690.11 EMD64395.1 - 4.5e-14 51.9 63.5 1.5e-13 50.2 39.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD64395.1 - 2.5e-06 26.0 20.0 3.4e-06 25.5 13.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EMD64396.1 - 3.6e-13 49.0 0.3 7.1e-13 48.0 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64396.1 - 4.3e-08 32.9 9.2 7.8e-08 32.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3295 PF11702.3 EMD64399.1 - 3.6e-134 448.5 39.1 4.3e-134 448.2 27.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EMD64399.1 - 1.5e-09 37.2 0.6 2.7e-09 36.4 0.4 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNA_pol_3_Rpc31 PF11705.3 EMD64399.1 - 0.063 13.2 8.5 11 5.8 7.0 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 EMD64399.1 - 3.4 8.0 6.8 12 6.3 4.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 EMD64399.1 - 4 6.3 7.0 6.5 5.6 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 EMD64399.1 - 7.8 6.7 11.4 16 5.7 7.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1180 PF06679.7 EMD64400.1 - 1.7 8.5 7.6 2.3 8.0 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Cpn60_TCP1 PF00118.19 EMD64404.1 - 2.9e-147 491.1 4.0 3.4e-147 491.0 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EMD64404.1 - 0.066 13.1 1.7 26 4.7 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo PF00385.19 EMD64405.1 - 3.7e-10 39.3 0.9 9.1e-10 38.0 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EMD64405.1 - 1.3e-09 37.7 0.0 1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain ImmE5 PF11480.3 EMD64405.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Colicin-E5 Imm protein PAN_4 PF14295.1 EMD64406.1 - 0.00026 20.6 1.2 0.00054 19.6 0.8 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EMD64406.1 - 0.0036 17.0 0.3 0.0077 15.9 0.2 1.5 1 0 0 1 1 1 1 PAN domain FAD_binding_4 PF01565.18 EMD64408.1 - 5.6e-21 74.4 3.2 1.6e-20 73.0 1.9 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMD64408.1 - 0.0002 21.2 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4286 PF14114.1 EMD64409.1 - 0.0032 17.6 0.2 2.5 8.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4286) CSS-motif PF12792.2 EMD64409.1 - 0.039 13.2 0.0 0.1 11.9 0.0 1.6 1 1 1 2 2 2 0 CSS motif domain associated with EAL Oxidored_molyb PF00174.14 EMD64411.1 - 7.6e-50 168.6 0.0 1.2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMD64411.1 - 7.1e-21 74.2 2.4 1.2e-20 73.4 1.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain TniQ PF06527.6 EMD64411.1 - 0.029 14.5 1.4 0.052 13.7 1.0 1.4 1 0 0 1 1 1 0 TniQ ACOX PF01756.14 EMD64412.1 - 8.5e-36 123.0 0.0 1.8e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMD64412.1 - 1.5e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMD64412.1 - 1.9e-05 24.0 0.1 4.6e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMD64412.1 - 0.00033 20.7 0.2 0.001 19.1 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SIS PF01380.17 EMD64413.1 - 6.3e-13 48.4 0.2 1.7e-12 47.0 0.2 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EMD64413.1 - 1.1e-05 25.1 0.7 0.0079 15.9 0.2 2.3 1 1 1 2 2 2 2 SIS domain PK_C PF02887.11 EMD64413.1 - 0.012 15.1 0.3 0.066 12.7 0.0 2.1 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Acetyltransf_1 PF00583.19 EMD64414.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD64414.1 - 9.8e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD64414.1 - 1.4e-05 25.1 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMD64414.1 - 0.00082 19.3 0.0 0.00098 19.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD64414.1 - 0.022 14.4 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 EMD64414.1 - 0.054 13.3 0.0 0.079 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1391 PF07151.7 EMD64414.1 - 0.18 11.3 0.4 0.5 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Amino_oxidase PF01593.19 EMD64415.1 - 3.1e-41 141.8 0.0 9.8e-31 107.3 0.1 2.2 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD64415.1 - 8e-08 32.2 0.0 3.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMD64415.1 - 0.00091 18.3 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD64415.1 - 0.0095 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD64415.1 - 0.031 14.6 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Chitin_synth_1 PF01644.12 EMD64415.1 - 0.075 12.8 0.1 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Chitin synthase Ribonuc_L-PSP PF01042.16 EMD64416.1 - 3.1e-31 107.6 0.0 4.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EMD64417.1 - 1e-07 31.5 1.8 5.3e-07 29.2 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.3 EMD64417.1 - 0.011 13.9 0.1 0.012 13.7 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1513 PF07433.6 EMD64417.1 - 0.14 11.0 0.1 0.32 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Abhydrolase_6 PF12697.2 EMD64418.1 - 9.3e-20 71.4 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD64418.1 - 1.9e-10 40.6 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD64418.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EMD64418.1 - 0.085 12.7 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Nucleotid_trans PF03407.11 EMD64420.1 - 2.7e-05 24.0 0.8 4.4e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EMD64420.1 - 8e-05 22.2 2.6 0.0014 18.1 1.8 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_8 PF01501.15 EMD64420.1 - 0.00093 18.5 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF3329 PF11808.3 EMD64421.1 - 0.4 10.7 2.6 2.3 8.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF2512 PF10710.4 EMD64421.1 - 3.5 7.0 8.8 0.37 10.2 2.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2512) ABC_tran PF00005.22 EMD64422.1 - 4.7e-32 111.1 2.0 3.3e-20 72.7 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EMD64422.1 - 6.6e-14 52.5 0.7 4.5e-05 23.5 0.0 3.2 3 0 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EMD64422.1 - 2.4e-08 33.6 5.4 2.4e-08 33.6 3.8 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EMD64422.1 - 1.3e-07 31.0 0.0 0.0085 15.3 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain E3_UbLigase_R4 PF13764.1 EMD64422.1 - 0.46 8.3 2.4 0.72 7.6 1.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Rtf2 PF04641.7 EMD64423.1 - 2.5 7.2 7.8 8.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger PAT1 PF09770.4 EMD64423.1 - 2.9 6.0 38.8 0.57 8.3 0.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TCO89 PF10452.4 EMD64425.1 - 1.1e-07 31.2 0.8 1.1e-05 24.5 0.0 3.6 3 1 0 3 3 3 2 TORC1 subunit TCO89 PT PF04886.7 EMD64426.1 - 3 7.2 16.9 7.5 5.9 2.5 3.2 2 1 0 2 2 2 0 PT repeat COesterase PF00135.23 EMD64427.1 - 7.3e-90 302.1 0.0 8.2e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD64427.1 - 3e-07 30.2 0.1 1.4e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Atx10homo_assoc PF09759.4 EMD64428.1 - 8.5e-28 96.0 0.2 1.6e-26 91.9 0.1 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HMG_box_2 PF09011.5 EMD64428.1 - 0.00024 21.3 0.1 0.00073 19.8 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EMD64428.1 - 0.0003 20.9 0.1 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CENP-Q PF13094.1 EMD64428.1 - 0.015 15.3 0.1 0.06 13.3 0.0 2.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NAAA-beta PF15508.1 EMD64428.1 - 0.12 12.7 0.7 2.1 8.7 0.0 2.8 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GatB_Yqey PF02637.13 EMD64428.1 - 0.14 11.8 0.2 14 5.4 0.0 3.2 3 0 0 3 3 3 0 GatB domain Prefoldin_3 PF13758.1 EMD64429.1 - 1.5e-26 92.0 2.3 1.5e-26 92.0 1.6 2.3 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EMD64429.1 - 1.8e-18 67.2 0.5 1.8e-18 67.2 0.3 7.1 7 2 1 8 8 8 2 Domain of unknown function (DUF3835) LEM PF03020.10 EMD64429.1 - 0.094 12.1 0.7 1.2 8.6 0.0 2.9 3 0 0 3 3 3 0 LEM domain DUF3618 PF12277.3 EMD64429.1 - 0.32 11.0 5.1 0.1 12.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF3367 PF11847.3 EMD64429.1 - 0.55 8.1 2.1 0.78 7.6 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) MAT1 PF06391.8 EMD64430.1 - 1.7e-29 102.8 2.3 2.3e-29 102.4 1.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EMD64430.1 - 0.00049 19.7 5.8 0.0028 17.3 1.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD64430.1 - 0.0035 16.9 4.6 0.013 15.1 3.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD64430.1 - 0.0073 16.1 5.3 0.032 14.0 3.7 1.9 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD64430.1 - 0.03 14.3 7.7 0.17 11.9 5.7 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD64430.1 - 0.086 12.5 6.3 0.36 10.5 4.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD64430.1 - 0.093 12.4 2.4 0.2 11.4 1.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EMD64430.1 - 0.24 11.2 2.0 0.44 10.4 1.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMD64430.1 - 0.32 10.9 3.0 0.89 9.4 2.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMD64430.1 - 0.55 9.8 4.8 12 5.5 1.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MARVEL PF01284.18 EMD64431.1 - 7.2e-08 32.3 5.8 1e-07 31.8 4.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EMD64431.1 - 0.082 12.4 3.1 0.16 11.4 2.1 1.5 1 1 0 1 1 1 0 SUR7/PalI family DUF1129 PF06570.6 EMD64431.1 - 0.18 11.1 2.3 0.28 10.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RTC PF01137.16 EMD64432.1 - 5.7e-22 77.6 0.0 1.1e-20 73.3 0.0 2.8 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase Tmemb_185A PF10269.4 EMD64432.1 - 0.079 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein TauD PF02668.11 EMD64435.1 - 2.7e-23 82.9 0.0 3.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EMD64435.1 - 0.0012 17.7 0.1 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 EMD64435.1 - 0.1 13.1 0.1 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 EMD64437.1 - 2.1e-62 207.0 16.8 2.6e-15 56.1 0.2 9.2 5 3 7 12 12 12 11 Tetratricopeptide repeat TPR_10 PF13374.1 EMD64437.1 - 2.9e-38 128.7 32.1 2e-07 30.7 0.1 11.3 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMD64437.1 - 2.3e-14 52.2 10.2 0.014 15.0 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMD64437.1 - 1.4e-13 49.6 21.4 0.14 12.1 0.3 9.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64437.1 - 3.2e-13 49.9 15.7 0.00093 19.8 0.2 7.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD64437.1 - 9.5e-12 44.3 18.4 0.0026 17.3 0.1 7.1 5 2 2 7 7 7 5 TPR repeat TPR_8 PF13181.1 EMD64437.1 - 9.2e-09 34.4 3.2 1.9 8.4 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD64437.1 - 1.7e-08 33.5 17.9 0.043 13.6 0.1 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD64437.1 - 2.5e-08 33.4 5.8 3.5 8.0 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD64437.1 - 8.5e-08 31.3 0.0 1.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 EMD64437.1 - 1.1e-07 31.8 22.9 0.53 11.0 0.1 10.0 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD64437.1 - 8.8e-07 29.1 15.2 0.025 14.9 0.1 6.2 5 2 2 7 7 6 2 Tetratricopeptide repeat AAA_22 PF13401.1 EMD64437.1 - 1.1e-06 28.7 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Apc3 PF12895.2 EMD64437.1 - 1e-05 25.5 1.4 1 9.5 0.0 5.5 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMD64437.1 - 0.0001 22.4 17.6 1.2 9.7 1.2 8.7 11 0 0 11 11 8 1 Tetratricopeptide repeat AAA_16 PF13191.1 EMD64437.1 - 0.0019 18.2 5.1 0.0043 17.0 0.2 3.6 3 1 0 3 3 3 1 AAA ATPase domain TPR_6 PF13174.1 EMD64437.1 - 0.0021 18.3 15.3 17 6.1 0.1 8.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EMD64437.1 - 0.0066 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase TPR_5 PF12688.2 EMD64437.1 - 0.0069 16.4 2.8 0.15 12.0 0.2 3.5 2 2 1 3 3 3 1 Tetratrico peptide repeat EFhand_Ca_insen PF08726.5 EMD64437.1 - 0.07 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand TPR_3 PF07720.7 EMD64437.1 - 0.25 11.2 2.6 41 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HET PF06985.6 EMD64439.1 - 1.4e-20 73.8 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 EMD64440.1 - 8.9e-57 192.4 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD64440.1 - 7.2e-39 133.3 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD64440.1 - 3e-08 32.9 0.0 0.0044 15.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD64440.1 - 1.5e-06 27.4 0.1 2.6e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD64440.1 - 0.00019 21.3 0.4 0.00068 19.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD64440.1 - 0.00044 20.3 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD64440.1 - 0.0013 18.5 0.1 0.13 12.0 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMD64440.1 - 0.0014 17.7 0.1 0.0025 16.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMD64440.1 - 0.0015 17.1 0.2 0.15 10.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMD64440.1 - 0.008 16.0 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD64440.1 - 0.0088 14.9 0.2 0.056 12.2 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EMD64440.1 - 0.011 14.6 0.1 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EMD64440.1 - 0.046 12.3 0.0 0.076 11.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyridox_oxidase PF01243.15 EMD64441.1 - 7.1e-12 45.1 0.0 2.4e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EMD64441.1 - 0.0001 22.3 0.0 0.02 15.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 EMD64441.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.16 EMD64441.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF572 PF04502.8 EMD64442.1 - 1.8 7.6 8.3 2.3 7.3 5.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM196 PF15265.1 EMD64442.1 - 3.8 6.6 10.0 4.5 6.3 7.0 1.0 1 0 0 1 1 1 0 FAM196 family MIP-T3 PF10243.4 EMD64442.1 - 4.5 5.6 15.6 5.6 5.3 10.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GTP_EFTU PF00009.22 EMD64443.1 - 1.7e-48 164.5 0.2 3.6e-48 163.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EMD64443.1 - 6.8e-21 74.1 1.3 6.8e-21 74.1 0.9 2.5 2 1 1 3 3 3 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EMD64443.1 - 9.7e-10 38.5 0.1 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD64443.1 - 9.6e-08 32.0 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD64443.1 - 1.3e-07 31.5 0.2 2.5e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMD64443.1 - 1.4e-05 25.6 0.4 0.00088 19.7 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein Ras PF00071.17 EMD64443.1 - 0.0022 17.4 0.3 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EMD64443.1 - 0.0046 16.1 0.0 0.46 9.6 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 EMD64443.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Septin PF00735.13 EMD64443.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 EMD64443.1 - 0.056 12.7 0.1 0.85 8.8 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B PTPA PF03095.10 EMD64444.1 - 3.4e-112 374.5 0.0 4.1e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AT_hook PF02178.14 EMD64445.1 - 0.12 12.1 7.7 0.34 10.7 2.7 2.9 2 0 0 2 2 2 0 AT hook motif APH PF01636.18 EMD64446.1 - 2.3e-08 34.0 0.0 1.3e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4355 PF14265.1 EMD64447.1 - 0.0046 16.9 2.4 0.0089 15.9 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) Wbp11 PF09429.5 EMD64447.1 - 0.031 14.2 5.3 0.072 13.0 3.7 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 CAF-1_p150 PF11600.3 EMD64448.1 - 5.5 6.3 25.9 9.9 5.4 18.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hex_IIIa PF02455.11 EMD64448.1 - 6 5.4 10.1 9 4.8 7.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF2433 PF10360.4 EMD64450.1 - 2.4e-53 179.9 0.0 3.9e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EMD64450.1 - 0.0084 15.9 0.0 0.026 14.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMD64450.1 - 0.02 14.3 0.0 0.058 12.7 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Herpes_UL32 PF06070.6 EMD64450.1 - 5.3 5.3 8.2 7.8 4.8 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HEAT PF02985.17 EMD64451.1 - 7.4e-20 69.1 10.8 4.6e-05 23.1 0.1 10.5 13 0 0 13 13 9 3 HEAT repeat HEAT_EZ PF13513.1 EMD64451.1 - 6.2e-16 58.3 10.2 0.00039 20.8 0.1 10.5 10 1 2 12 12 11 4 HEAT-like repeat HEAT_2 PF13646.1 EMD64451.1 - 3.6e-15 56.0 9.9 0.00049 20.3 0.1 7.8 4 2 5 9 9 9 4 HEAT repeats IBN_N PF03810.14 EMD64451.1 - 2.8e-10 39.9 0.5 1.1e-09 38.0 0.4 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EMD64451.1 - 2e-09 37.7 0.0 0.34 11.3 0.0 5.4 4 1 1 5 5 4 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EMD64451.1 - 2.3e-08 33.5 3.9 0.33 10.8 0.0 6.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EMD64451.1 - 1.5e-07 30.1 0.0 0.0054 15.1 0.0 4.1 4 1 0 5 5 5 2 Adaptin N terminal region MMS19_C PF12460.3 EMD64451.1 - 6.4e-06 25.1 0.2 0.044 12.5 0.0 4.2 4 1 0 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EMD64451.1 - 0.00022 20.6 0.0 0.47 9.7 0.0 4.1 4 1 1 5 5 5 1 CLASP N terminal UME PF08064.8 EMD64451.1 - 0.00056 19.8 0.0 1.5 8.8 0.0 4.4 5 1 1 6 6 6 1 UME (NUC010) domain DUF2435 PF10363.4 EMD64451.1 - 0.0014 18.4 0.0 5.9 6.8 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) DUF3385 PF11865.3 EMD64451.1 - 0.0043 17.0 0.0 4.4 7.2 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) MCM_N PF14551.1 EMD64451.1 - 0.019 15.4 0.0 1.2 9.6 0.0 3.1 3 0 0 3 3 2 0 MCM N-terminal domain DUF4042 PF13251.1 EMD64451.1 - 0.063 12.7 1.8 5.5 6.4 0.0 4.6 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) DUF3295 PF11702.3 EMD64451.1 - 2.3 7.0 4.7 3.9 6.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Patched PF02460.13 EMD64452.1 - 1.2e-71 241.7 8.3 2.1e-47 161.5 0.0 2.4 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 EMD64452.1 - 3.3e-52 175.9 5.6 3.3e-52 175.9 3.9 3.6 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EMD64452.1 - 2.4e-06 26.4 29.8 0.00011 21.0 5.9 2.5 2 0 0 2 2 2 2 MMPL family DUF2207 PF09972.4 EMD64452.1 - 0.0029 16.2 3.2 0.04 12.5 0.0 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) IncA PF04156.9 EMD64452.1 - 0.5 9.9 0.0 0.5 9.9 0.0 5.1 5 0 0 5 5 5 0 IncA protein ACR_tran PF00873.14 EMD64452.1 - 6.5 4.0 20.7 0.072 10.4 8.6 1.7 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Aldo_ket_red PF00248.16 EMD64453.1 - 2.3e-46 157.8 0.0 2.8e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 EMD64454.1 - 7e-07 28.7 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64454.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LAMTOR PF15454.1 EMD64457.1 - 6.1e-16 58.4 1.7 6.1e-16 58.4 1.2 1.5 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator zf-UDP PF14569.1 EMD64458.1 - 0.014 15.1 1.5 0.014 15.1 1.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 EMD64458.1 - 0.087 12.4 5.1 0.24 11.0 3.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2151 PF10221.4 EMD64458.1 - 0.26 9.4 1.9 0.45 8.6 1.3 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator TEBP_beta PF07404.6 EMD64458.1 - 0.53 9.3 8.0 0.9 8.6 5.6 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) ABC_tran PF00005.22 EMD64459.1 - 2.5e-32 112.0 0.0 5.3e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMD64459.1 - 9.5e-27 94.0 5.9 9.5e-27 94.0 4.1 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EMD64459.1 - 0.0001 21.6 0.0 0.00085 18.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD64459.1 - 0.00083 19.3 0.1 1.2 9.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD64459.1 - 0.0018 18.3 0.1 0.0041 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMD64459.1 - 0.0077 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMD64459.1 - 0.026 13.9 0.2 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EMD64459.1 - 0.095 12.8 0.2 0.46 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD64459.1 - 0.13 11.8 1.6 0.6 9.6 0.4 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain p450 PF00067.17 EMD64460.1 - 1.9e-77 260.7 0.0 2.4e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3762 PF12591.3 EMD64461.1 - 0.045 13.7 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) PBP PF01161.15 EMD64462.1 - 7.3e-22 77.7 0.0 8.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3068 PF11271.3 EMD64464.1 - 0.032 13.3 0.2 0.054 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) zf-MYND PF01753.13 EMD64466.1 - 6.4e-11 41.9 16.9 1.2e-10 41.0 11.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EMD64466.1 - 0.14 12.0 7.2 0.25 11.2 5.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FAD_binding_4 PF01565.18 EMD64467.1 - 5.4e-17 61.5 0.1 8.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD64467.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Cation_efflux PF01545.16 EMD64468.1 - 0.0056 15.7 0.6 0.0075 15.3 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family PhoD PF09423.5 EMD64471.1 - 2.9e-157 523.8 6.8 3.4e-157 523.6 4.7 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase ADH_zinc_N_2 PF13602.1 EMD64471.1 - 6e-25 88.5 0.0 1.6e-24 87.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD64471.1 - 5.9e-15 54.9 0.7 1.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD64471.1 - 1.1e-06 28.3 5.0 2.4e-06 27.2 0.0 3.4 3 2 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD64472.1 - 3e-15 55.9 0.0 4.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD64472.1 - 3.5e-09 36.4 0.1 8.4e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD64472.1 - 4.7e-05 24.2 0.0 8.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Med7 PF05983.6 EMD64473.1 - 6.1e-45 152.9 0.4 8.2e-45 152.4 0.3 1.2 1 0 0 1 1 1 1 MED7 protein Macoilin PF09726.4 EMD64473.1 - 0.031 12.5 0.0 0.04 12.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein LTXXQ PF07813.7 EMD64473.1 - 0.067 13.6 2.4 1.1 9.8 1.1 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein DUF2235 PF09994.4 EMD64474.1 - 6e-62 209.5 0.0 1.3e-61 208.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tom37 PF10568.4 EMD64474.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Oxidored_FMN PF00724.15 EMD64475.1 - 1.7e-68 231.1 0.0 2.3e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF202 PF02656.10 EMD64477.1 - 0.68 10.1 5.6 2.7 8.2 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SF-assemblin PF06705.6 EMD64478.1 - 0.0041 16.3 0.9 0.0044 16.2 0.6 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1388 PF07142.7 EMD64479.1 - 8.8e-06 25.3 10.0 2.9e-05 23.6 6.9 1.9 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) DUF390 PF04094.9 EMD64479.1 - 0.33 8.9 3.6 0.42 8.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) HpaP PF09483.5 EMD64479.1 - 1.4 8.8 12.6 3 7.7 8.7 1.6 1 0 0 1 1 1 0 Type III secretion protein (HpaP) HSP70 PF00012.15 EMD64480.1 - 5.2e-266 883.3 14.3 5.9e-266 883.1 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD64480.1 - 2.1e-20 72.5 0.8 3.6e-19 68.5 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EMD64480.1 - 0.0044 15.9 0.3 0.068 11.9 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EMD64480.1 - 0.031 13.8 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EMD64480.1 - 0.034 13.2 2.7 0.49 9.4 0.1 3.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EMD64480.1 - 1.2 8.9 8.5 2.3 8.1 0.2 3.7 3 1 0 3 3 3 0 Cell division protein FtsA DUF1769 PF08588.5 EMD64481.1 - 1.7e-22 79.0 0.6 3.4e-22 78.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Gpi16 PF04113.9 EMD64483.1 - 6.4e-229 760.6 0.0 8.1e-229 760.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 EMD64484.1 - 4.5e-73 245.8 2.8 5.7e-73 245.5 2.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF2215 PF10225.4 EMD64484.1 - 0.069 12.5 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Atg14 PF10186.4 EMD64484.1 - 0.16 10.9 1.6 0.23 10.3 1.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EMD64484.1 - 0.17 10.3 2.2 0.25 9.7 1.5 1.3 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 EMD64484.1 - 0.86 10.3 5.9 0.26 12.0 0.3 2.6 2 1 1 3 3 3 0 Occludin homology domain GRP PF07172.6 EMD64484.1 - 1.7 9.1 26.6 1.3 9.5 16.6 2.0 2 0 0 2 2 2 0 Glycine rich protein family DEAD PF00270.24 EMD64485.1 - 1.3e-41 141.8 0.0 2.6e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD64485.1 - 6.5e-25 86.8 0.0 1.9e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMD64485.1 - 0.024 13.4 0.0 0.048 12.4 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain FtsJ PF01728.14 EMD64486.1 - 5.3e-61 205.7 0.0 6.8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.20 EMD64487.1 - 3.2e-71 239.5 0.0 4.5e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64487.1 - 7e-45 153.1 0.0 1.1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMD64487.1 - 6.8e-22 77.6 0.5 2.6e-21 75.7 0.2 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EMD64487.1 - 6.6e-08 31.8 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD64487.1 - 0.014 15.1 3.0 0.026 14.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EMD64487.1 - 0.031 13.3 0.6 0.083 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EMD64487.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Ofd1_CTDD PF10637.4 EMD64487.1 - 0.16 11.0 0.8 0.28 10.2 0.5 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term VHS PF00790.14 EMD64488.1 - 6.9e-36 122.9 0.4 1.2e-35 122.1 0.3 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EMD64488.1 - 2.8e-16 58.6 0.0 6.2e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD64488.1 - 1.1e-15 56.9 0.1 2.1e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMD64488.1 - 6.1e-15 54.4 0.0 1.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 EMD64488.1 - 0.011 15.7 0.3 0.03 14.2 0.2 1.7 1 0 0 1 1 1 0 GAT domain PTA_PTB PF01515.14 EMD64488.1 - 0.014 14.4 0.0 0.034 13.2 0.0 1.5 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase UIM PF02809.15 EMD64488.1 - 0.035 13.6 3.3 0.093 12.3 2.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif HEAT_2 PF13646.1 EMD64488.1 - 0.14 12.4 0.8 0.37 11.1 0.2 2.1 2 1 0 2 2 2 0 HEAT repeats KH_1 PF00013.24 EMD64490.1 - 5.8e-84 275.6 24.5 1.9e-12 46.6 0.1 12.3 13 0 0 13 13 13 8 KH domain KH_3 PF13014.1 EMD64490.1 - 5.7e-62 204.5 24.7 2.6e-10 39.7 0.3 12.1 13 0 0 13 13 13 8 KH domain SLS PF14611.1 EMD64490.1 - 1.2e-14 54.2 0.8 0.038 13.4 0.0 8.2 7 2 1 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EMD64490.1 - 1.4e-12 47.0 14.7 0.11 12.0 0.0 7.6 7 0 0 7 7 7 5 KH domain BMC PF00936.14 EMD64490.1 - 0.00056 19.5 0.6 1.6 8.4 0.1 3.4 3 0 0 3 3 3 2 BMC domain KH_4 PF13083.1 EMD64490.1 - 0.007 15.9 2.5 1.2 8.8 0.0 4.7 6 0 0 6 6 6 1 KH domain KH_5 PF13184.1 EMD64490.1 - 0.097 12.4 7.1 8.5 6.2 0.1 5.3 6 0 0 6 6 6 0 NusA-like KH domain IncA PF04156.9 EMD64490.1 - 0.42 10.1 4.5 1.6 8.2 0.2 2.9 3 0 0 3 3 3 0 IncA protein PHY PF00360.15 EMD64491.1 - 2.4e-28 98.5 0.0 6.7e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EMD64491.1 - 2.6e-20 72.2 0.1 6.4e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EMD64491.1 - 2.6e-16 60.1 0.0 1.2e-15 58.0 0.0 2.2 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 EMD64491.1 - 2.8e-16 59.4 0.0 9.2e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMD64491.1 - 1.2e-13 50.8 0.7 4.1e-13 49.1 0.5 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EMD64491.1 - 3.6e-08 33.8 0.0 1.3e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.1 EMD64491.1 - 0.0064 16.2 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Flavoprotein PF02441.14 EMD64492.1 - 6.1e-14 51.7 0.0 2e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Flavoprotein DGF-1_4 PF11024.3 EMD64492.1 - 0.041 14.2 0.2 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 GH-E PF14410.1 EMD64492.1 - 2.4 8.3 7.0 0.45 10.6 0.1 2.8 2 1 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Cyt-b5 PF00173.23 EMD64493.1 - 6.9e-24 83.4 0.2 8.9e-24 83.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUC153 PF08159.7 EMD64494.1 - 1.3e-14 53.4 2.5 3.2e-14 52.2 1.7 1.7 1 0 0 1 1 1 1 NUC153 domain Med13_C PF06333.7 EMD64495.1 - 6.9e-73 245.5 0.0 8.5e-72 242.0 0.0 2.9 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EMD64495.1 - 3.4e-22 78.7 1.5 6.9e-22 77.6 1.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal zf-DHHC PF01529.15 EMD64497.1 - 5.5e-34 117.0 1.2 5.5e-34 117.0 0.8 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase TatC PF00902.13 EMD64497.1 - 0.0016 17.8 0.2 0.0016 17.8 0.2 2.7 3 0 0 3 3 3 1 Sec-independent protein translocase protein (TatC) Adeno_E1A PF02703.9 EMD64497.1 - 0.41 10.0 4.1 0.61 9.4 2.9 1.2 1 0 0 1 1 1 0 Early E1A protein Myb_DNA-bind_2 PF08914.6 EMD64498.1 - 8.9e-24 83.0 0.5 2e-23 81.9 0.4 1.6 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.3 EMD64498.1 - 5.6e-15 55.0 0.0 2.9e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 EMD64498.1 - 2.2e-07 31.3 11.6 4.5e-06 27.1 0.0 4.0 3 2 0 3 3 3 2 Rap1, DNA-binding HMG_box PF00505.14 EMD64498.1 - 3.7e-05 23.9 2.4 5.5e-05 23.3 0.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD64498.1 - 0.0054 17.0 1.9 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 HMG-box domain zf-Nse PF11789.3 EMD64499.1 - 1.2e-23 82.3 0.8 2.3e-23 81.4 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMD64499.1 - 4.5e-05 23.0 0.3 8.9e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EMD64499.1 - 0.012 15.0 0.5 0.024 14.1 0.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Mito_carr PF00153.22 EMD64500.1 - 4.7e-56 186.4 4.8 1e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-actin_cap_A PF01267.12 EMD64501.1 - 2e-88 295.9 0.0 2.2e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Phage_connect_1 PF05135.8 EMD64501.1 - 0.028 14.5 0.1 0.14 12.3 0.0 2.2 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein VHS PF00790.14 EMD64504.1 - 4.4e-25 87.9 0.0 9.4e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EMD64504.1 - 8.2e-10 38.5 1.1 1.6e-09 37.6 0.7 1.4 1 0 0 1 1 1 1 GAT domain DUF2360 PF10152.4 EMD64504.1 - 2.4 8.4 8.7 2.9 8.1 1.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Fungal_trans PF04082.13 EMD64505.1 - 8.4e-21 74.0 5.1 1.5e-20 73.1 3.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain VSP PF03302.8 EMD64507.1 - 0.0031 16.2 0.5 0.0036 16.0 0.4 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein IlvB_leader PF08049.6 EMD64507.1 - 0.08 12.6 4.3 0.13 12.0 3.0 1.3 1 0 0 1 1 1 0 IlvB leader peptide IncA PF04156.9 EMD64507.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 IncA protein CD99L2 PF12301.3 EMD64507.1 - 0.31 10.7 2.2 0.17 11.5 0.2 1.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 Ribosomal_L33 PF00471.15 EMD64509.1 - 1.4e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Sugar_tr PF00083.19 EMD64510.1 - 2.7e-102 342.6 13.8 3e-102 342.5 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD64510.1 - 2.2e-22 79.2 23.8 2.5e-17 62.6 2.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.3 EMD64510.1 - 0.72 9.9 4.1 1.9 8.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Peptidase_S10 PF00450.17 EMD64511.1 - 3.5e-103 345.9 0.5 4e-103 345.7 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PNP_UDP_1 PF01048.15 EMD64514.1 - 1e-11 44.2 0.1 1.7e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily YopR_core PF09025.5 EMD64514.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 YopR Core WD40 PF00400.27 EMD64515.1 - 1.8e-66 217.8 9.1 6.1e-14 51.2 0.1 6.2 5 1 1 6 6 6 5 WD domain, G-beta repeat HET PF06985.6 EMD64515.1 - 1.3e-21 77.2 6.3 1e-19 71.0 4.4 2.8 2 1 0 2 2 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD64515.1 - 3.6e-12 45.2 2.5 0.0091 14.1 0.1 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF1513 PF07433.6 EMD64515.1 - 8e-07 28.2 2.2 0.091 11.6 0.1 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF1513) NACHT PF05729.7 EMD64515.1 - 2.7e-05 23.8 0.1 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EMD64515.1 - 9.8e-05 21.9 0.0 28 4.5 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EMD64515.1 - 0.00016 21.4 0.0 0.41 10.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 EMD64515.1 - 0.00024 21.1 0.3 0.00024 21.1 0.2 3.3 3 2 0 3 3 2 1 AAA ATPase domain Proteasome_A_N PF10584.4 EMD64515.1 - 0.00043 19.5 0.0 51 3.3 0.0 4.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature AAA PF00004.24 EMD64515.1 - 0.0033 17.6 0.2 0.013 15.6 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TruB_C PF09142.6 EMD64515.1 - 0.0044 16.6 0.5 48 3.6 0.0 4.3 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal DUF1258 PF06869.7 EMD64515.1 - 0.0084 15.2 0.0 7.3 5.6 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1258) AAA_22 PF13401.1 EMD64515.1 - 0.0099 16.0 0.0 0.031 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain IKI3 PF04762.7 EMD64515.1 - 0.011 13.5 0.0 2.2 5.9 0.0 2.3 1 1 0 2 2 2 0 IKI3 family NB-ARC PF00931.17 EMD64515.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 EMD64515.1 - 0.039 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.1 EMD64515.1 - 0.045 13.6 3.3 0.89 9.4 0.0 3.5 3 1 0 3 3 3 0 AAA domain Sial-lect-inser PF09264.5 EMD64515.1 - 0.064 12.5 0.1 1.7 7.9 0.0 2.9 1 1 1 2 2 2 0 Vibrio cholerae sialidase, lectin insertion AAA_17 PF13207.1 EMD64515.1 - 0.069 13.9 0.0 0.27 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EMD64515.1 - 0.092 11.9 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 EMD64515.1 - 0.12 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TFIIIC_delta PF12657.2 EMD64515.1 - 0.13 11.9 2.2 6.4 6.4 0.2 3.8 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term APS_kinase PF01583.15 EMD64515.1 - 0.2 11.3 0.1 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1212 PF06738.7 EMD64517.1 - 3.9e-48 163.4 8.2 8.2e-47 159.1 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMD64517.1 - 7.2e-20 71.2 28.2 3.1e-13 49.8 1.4 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EMD64517.1 - 0.031 14.4 5.1 0.027 14.6 1.7 2.1 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) FAD_binding_3 PF01494.14 EMD64518.1 - 2.1e-38 132.3 0.0 3.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD64518.1 - 1.9e-05 24.5 0.1 4.5e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD64518.1 - 9.3e-05 21.6 0.1 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMD64518.1 - 0.00024 20.1 0.1 0.0072 15.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD64518.1 - 0.00027 21.2 0.1 0.0044 17.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD64518.1 - 0.00038 20.3 0.2 0.0012 18.8 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD64518.1 - 0.0046 15.9 0.2 0.0076 15.2 0.2 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD64518.1 - 0.0054 16.8 0.2 0.02 14.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD64518.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD64518.1 - 0.009 14.5 0.7 0.013 14.0 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMD64518.1 - 0.013 14.6 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD64518.1 - 0.091 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding RRF PF01765.14 EMD64518.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor adh_short_C2 PF13561.1 EMD64519.1 - 3e-18 66.4 0.9 4.8e-18 65.8 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD64519.1 - 5.8e-15 55.6 1.8 3.6e-14 53.0 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD64519.1 - 3.4e-06 26.8 0.1 7.5e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 KR domain RNA_pol_Rpc4 PF05132.9 EMD64519.1 - 0.12 12.3 0.1 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 RNA polymerase III RPC4 MFS_1 PF07690.11 EMD64520.1 - 3.7e-31 108.1 56.0 3.7e-31 108.1 38.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64520.1 - 2.5e-06 26.3 13.2 2.5e-06 26.3 9.2 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter NDUF_B8 PF05821.6 EMD64520.1 - 0.21 11.2 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF3735 PF12537.3 EMD64520.1 - 0.22 11.5 0.9 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) MFS_3 PF05977.8 EMD64520.1 - 6 4.8 17.7 0.024 12.7 2.2 2.9 3 1 0 3 3 3 0 Transmembrane secretion effector DUF2306 PF10067.4 EMD64521.1 - 1e-12 48.0 9.0 2.2e-12 46.9 6.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EMD64521.1 - 0.00058 19.8 0.8 0.00058 19.8 0.6 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF420) Aminotran_1_2 PF00155.16 EMD64522.1 - 2.6e-25 89.1 0.0 3.2e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD64522.1 - 0.00017 20.0 0.0 0.00028 19.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMD64522.1 - 0.0003 19.9 0.1 0.00091 18.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMD64522.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EMD64522.1 - 0.0028 16.5 0.1 0.0088 14.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-III TGFb_propeptide PF00688.13 EMD64522.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 TGF-beta propeptide Acyl_transf_1 PF00698.16 EMD64523.1 - 9.2e-64 215.7 0.2 2.8e-63 214.1 0.2 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EMD64523.1 - 1.1e-60 205.2 0.0 2.2e-60 204.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMD64523.1 - 1.4e-58 197.5 0.0 1.1e-57 194.6 0.0 2.5 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EMD64523.1 - 3.4e-56 190.5 0.1 6.6e-56 189.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EMD64523.1 - 9e-44 149.3 0.1 1.4e-42 145.4 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD64523.1 - 1.1e-32 112.3 0.3 3.6e-32 110.6 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD64523.1 - 2.2e-14 53.1 0.1 2.4e-13 49.7 0.1 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMD64523.1 - 5.6e-14 52.1 0.0 2e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD64523.1 - 1.2e-13 51.3 0.0 4.8e-13 49.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EMD64523.1 - 1.1e-08 35.1 0.1 8.8e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EMD64523.1 - 7.2e-08 32.1 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD64523.1 - 8.2e-06 26.3 0.0 4.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EMD64523.1 - 0.00012 22.1 0.1 0.66 9.9 0.0 2.8 2 0 0 2 2 2 2 NADH(P)-binding Methyltransf_11 PF08241.7 EMD64523.1 - 0.00014 22.2 0.0 0.00041 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EMD64523.1 - 0.0037 16.5 0.1 0.12 11.6 0.0 2.6 2 0 0 2 2 2 1 NmrA-like family ADH_N PF08240.7 EMD64523.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EMD64523.1 - 0.096 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0118 PF01594.11 EMD64524.1 - 0.025 13.5 2.1 0.041 12.8 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF20 Cwf_Cwc_15 PF04889.7 EMD64524.1 - 0.077 12.6 3.5 0.11 12.2 2.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF972 PF06156.8 EMD64524.1 - 2.4 8.5 8.5 31 4.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ank_4 PF13637.1 EMD64525.1 - 2.4e-32 110.7 4.9 9.4e-10 38.7 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD64525.1 - 4.8e-31 106.9 1.0 5.1e-16 58.7 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD64525.1 - 2.2e-26 90.2 7.0 5.7e-09 35.3 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EMD64525.1 - 5.9e-22 77.1 5.0 2.7e-09 36.9 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64525.1 - 7.4e-21 72.1 5.5 1e-06 28.3 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.7 EMD64525.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMD64525.1 - 0.0041 17.2 0.0 0.034 14.3 0.0 2.5 3 1 1 4 4 4 1 AAA domain Ank_2 PF12796.2 EMD64526.1 - 3.2e-18 65.8 0.0 6.3e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD64526.1 - 3.9e-16 57.9 0.0 0.00011 21.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMD64526.1 - 1.6e-14 53.6 0.0 4.5e-05 23.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMD64526.1 - 9.1e-14 51.5 0.0 2.4e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64526.1 - 2.3e-13 48.9 0.0 0.00086 19.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF1654 PF07867.6 EMD64526.1 - 0.12 11.8 0.8 0.7 9.3 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1654) DUF3425 PF11905.3 EMD64527.1 - 3e-12 46.6 0.6 7.2e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMD64527.1 - 0.078 12.9 5.0 0.13 12.2 3.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF2956 PF11169.3 EMD64527.1 - 0.091 12.7 1.2 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Pap_E4 PF02711.9 EMD64527.1 - 0.67 10.8 5.2 1.5 9.7 3.6 1.6 1 0 0 1 1 1 0 E4 protein NmrA PF05368.8 EMD64528.1 - 1.7e-27 96.2 0.0 1.2e-25 90.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD64528.1 - 7e-08 32.6 0.0 1.1e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMD64528.1 - 4.9e-05 22.8 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMD64528.1 - 0.00045 20.2 0.0 0.001 19.0 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 EMD64528.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AflR PF08493.5 EMD64530.1 - 3.8e-08 32.7 2.3 3.8e-08 32.7 1.6 2.8 1 1 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EMD64530.1 - 4e-08 33.0 12.2 9.1e-08 31.8 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX15-CtaA PF02628.10 EMD64531.1 - 1.5e-94 316.2 12.9 1.9e-94 315.9 8.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BTB PF00651.26 EMD64532.1 - 0.00014 21.7 0.0 0.00033 20.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Chromate_transp PF02417.10 EMD64532.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Chromate transporter PNP_UDP_1 PF01048.15 EMD64535.1 - 8.3e-37 126.3 0.0 1e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Amidase PF01425.16 EMD64536.1 - 9.9e-70 235.5 1.1 3.1e-69 233.9 0.7 1.7 1 1 0 1 1 1 1 Amidase LT-IIB PF06453.6 EMD64536.1 - 0.19 11.4 1.1 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) FIVAR PF07554.8 EMD64536.1 - 4.1 7.7 6.9 3.1 8.1 0.1 3.6 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain SelR PF01641.13 EMD64537.1 - 5.8e-46 155.2 0.0 8.1e-46 154.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EMD64537.1 - 0.041 13.7 0.7 6.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EMD64537.1 - 0.17 11.2 1.6 0.66 9.3 0.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-MYND PF01753.13 EMD64538.1 - 0.0031 17.3 1.9 0.0046 16.8 1.3 1.3 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EMD64538.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Life-span regulatory factor MFS_1 PF07690.11 EMD64539.1 - 3.3e-22 78.6 22.5 3.3e-22 78.6 15.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EMD64540.1 - 2.1e-21 76.9 0.0 4.5e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD64540.1 - 1.6e-14 52.9 0.0 3.2e-11 42.1 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD64540.1 - 2.6e-10 40.1 0.0 1.4e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMD64540.1 - 2.6e-05 23.3 0.1 0.0057 15.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD64540.1 - 0.0012 18.7 0.0 0.0057 16.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD64540.1 - 0.015 14.1 0.0 0.31 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD64540.1 - 0.024 14.4 0.4 0.27 10.9 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMD64540.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF877 PF05943.7 EMD64540.1 - 0.075 11.5 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Pyr_redox PF00070.22 EMD64540.1 - 0.21 12.0 1.4 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Asparaginase_2 PF01112.13 EMD64541.1 - 2.5e-19 69.1 1.1 5.8e-15 54.8 0.1 2.2 2 0 0 2 2 2 2 Asparaginase Cation_ATPase_C PF00689.16 EMD64542.1 - 0.56 9.7 19.0 1.2 8.5 7.0 2.7 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF500 PF04366.7 EMD64543.1 - 5.5e-45 151.8 0.0 1e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EMD64543.1 - 1.3e-13 50.1 0.3 3.2e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMD64543.1 - 4.7e-12 45.2 0.0 1.3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMD64543.1 - 2.9e-11 42.7 0.0 5.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain adh_short PF00106.20 EMD64545.1 - 1.2e-17 64.3 0.6 1.8e-16 60.5 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMD64545.1 - 0.001 19.0 0.1 0.24 11.3 0.0 2.1 1 1 1 2 2 2 2 NADH(P)-binding KR PF08659.5 EMD64545.1 - 0.0048 16.5 0.8 3.1 7.4 0.0 2.7 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 EMD64545.1 - 0.16 11.4 0.1 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 EMD64546.1 - 9.2e-42 143.0 0.1 2.2e-32 112.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMD64546.1 - 2e-16 59.6 0.1 5.1e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMD64546.1 - 0.00057 18.7 0.1 0.28 9.8 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EMD64546.1 - 0.00063 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF572 PF04502.8 EMD64547.1 - 4.8e-60 203.4 0.0 5.5e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Herpes_pp85 PF04637.7 EMD64547.1 - 0.0065 14.8 0.5 0.0093 14.3 0.3 1.1 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Elongin_A PF06881.6 EMD64547.1 - 4.3 7.7 7.9 18 5.7 0.0 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GTP_EFTU PF00009.22 EMD64548.1 - 3e-44 150.7 0.0 5.1e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMD64548.1 - 1.7e-19 69.7 0.1 3.7e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD64548.1 - 3.1e-05 24.0 0.0 0.00011 22.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD64548.1 - 0.00023 21.1 0.3 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMD64548.1 - 0.023 13.3 0.5 0.036 12.7 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Ran-binding PF05508.6 EMD64549.1 - 2.4e-113 378.0 0.0 3.1e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.12 EMD64550.1 - 1.1e-14 53.8 1.0 2.9e-14 52.5 0.7 1.8 1 0 0 1 1 1 1 BSD domain BSP_II PF05432.6 EMD64550.1 - 0.005 16.1 18.8 0.005 16.1 13.1 2.6 3 1 0 3 3 3 1 Bone sialoprotein II (BSP-II) WGG PF10273.4 EMD64551.1 - 2.7e-28 97.8 0.7 4.7e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 KfrA_N PF11740.3 EMD64551.1 - 0.0031 17.9 0.1 0.0049 17.2 0.1 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term SURF2 PF05477.6 EMD64551.1 - 0.0049 16.0 4.0 0.0072 15.4 2.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Tautomerase_2 PF14552.1 EMD64551.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tautomerase enzyme RRP7 PF12923.2 EMD64551.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.1 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) SDA1 PF05285.7 EMD64551.1 - 0.32 10.2 6.7 0.43 9.7 4.7 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.20 EMD64555.1 - 3.8e-69 232.7 0.0 5.4e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64555.1 - 4.2e-32 111.2 0.0 6.3e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_18 PF00704.23 EMD64555.1 - 6.3e-08 32.4 0.0 2.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 UBA PF00627.26 EMD64555.1 - 2.6e-07 30.3 0.0 8.1e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Kinase-like PF14531.1 EMD64555.1 - 0.082 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RuvA_C PF07499.8 EMD64555.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain Arrestin_N PF00339.24 EMD64556.1 - 1.8e-14 53.8 0.1 2.8e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMD64556.1 - 4.2e-14 52.8 0.1 9.8e-13 48.3 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.27 EMD64558.1 - 3.3e-22 77.4 9.2 1.4e-06 27.9 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD64558.1 - 0.0051 16.5 0.1 0.063 12.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EMD64558.1 - 0.0095 13.8 0.0 0.19 9.4 0.0 2.0 1 1 1 2 2 2 1 IKI3 family Cytochrom_D1 PF02239.11 EMD64558.1 - 0.019 13.2 0.0 0.078 11.2 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain DUF3776 PF12618.3 EMD64558.1 - 0.14 12.7 0.3 0.14 12.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3776) DUF1273 PF06908.6 EMD64558.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) EF_assoc_2 PF08356.7 EMD64559.1 - 1.1e-33 114.8 0.0 2.2e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EMD64559.1 - 1.4e-33 115.9 0.0 3.1e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EMD64559.1 - 5.6e-31 105.6 0.1 1e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EMD64559.1 - 9.1e-26 90.1 0.0 6.2e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EMD64559.1 - 4.4e-08 33.0 0.0 0.00074 19.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EMD64559.1 - 4.6e-06 26.7 0.1 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMD64559.1 - 3.8e-05 22.9 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMD64559.1 - 4.9e-05 22.7 0.1 0.053 13.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD64559.1 - 6.8e-05 23.0 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.1 EMD64559.1 - 0.00017 21.1 4.4 0.023 14.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EMD64559.1 - 0.00021 20.3 1.5 0.69 9.3 0.5 2.8 2 0 0 2 2 2 2 EF hand ABC_tran PF00005.22 EMD64559.1 - 0.00035 20.8 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EMD64559.1 - 0.0006 19.6 0.2 0.4 10.4 0.0 2.8 3 0 0 3 3 2 1 Dynamin family EF-hand_5 PF13202.1 EMD64559.1 - 0.00066 18.9 2.9 0.17 11.3 1.5 2.7 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.17 EMD64559.1 - 0.00076 19.6 0.1 0.43 10.7 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.1 EMD64559.1 - 0.0023 17.5 0.0 0.79 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMD64559.1 - 0.004 16.8 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EMD64559.1 - 0.0074 15.2 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arf PF00025.16 EMD64559.1 - 0.0088 15.3 0.0 7.7 5.7 0.1 3.2 2 1 0 2 2 2 0 ADP-ribosylation factor family EF-hand_7 PF13499.1 EMD64559.1 - 0.013 15.6 0.9 4.5 7.4 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Septin PF00735.13 EMD64559.1 - 0.017 14.1 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin GTP_EFTU PF00009.22 EMD64559.1 - 0.034 13.5 0.0 0.76 9.1 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.1 EMD64559.1 - 0.035 13.7 3.1 1.8 8.2 1.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair AAA_18 PF13238.1 EMD64559.1 - 0.046 14.0 0.1 3.5 7.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EMD64559.1 - 0.048 13.3 0.0 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EMD64559.1 - 0.071 12.6 0.3 12 5.3 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EMD64559.1 - 0.08 12.6 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EMD64559.1 - 0.091 13.0 0.0 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EMD64559.1 - 0.11 11.6 0.2 0.65 9.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.1 EMD64559.1 - 0.11 12.4 1.3 2.5 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EMD64559.1 - 0.11 12.3 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMD64559.1 - 0.13 12.4 0.2 8.7 6.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMD64559.1 - 0.14 11.5 0.0 17 4.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EMD64559.1 - 0.15 11.6 0.0 22 4.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zds_C PF08632.5 EMD64560.1 - 6e-31 105.6 1.0 1e-30 104.8 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term PAT1 PF09770.4 EMD64560.1 - 0.00031 19.1 88.9 0.027 12.7 16.8 2.4 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Cupin_5 PF06172.6 EMD64561.1 - 9e-23 80.7 0.0 2.8e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily (DUF985) zf-UBP PF02148.14 EMD64562.1 - 0.026 14.6 0.5 28 4.9 0.0 3.4 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Pollen_allerg_1 PF01357.16 EMD64562.1 - 0.044 13.5 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pollen allergen Fe-ADH PF00465.14 EMD64563.1 - 7.7e-104 347.2 0.0 9.8e-104 346.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMD64563.1 - 7.5e-15 54.9 0.0 9e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Dehydratase_MU PF02288.10 EMD64563.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Dehydratase medium subunit SET PF00856.23 EMD64564.1 - 1.1e-13 51.7 0.3 2.6e-11 44.0 0.0 3.4 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.1 EMD64564.1 - 0.069 13.0 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Cu-oxidase_3 PF07732.10 EMD64565.1 - 4.3e-42 142.5 11.0 4.1e-39 132.9 0.9 3.3 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD64565.1 - 6.6e-35 119.6 1.3 6.6e-35 119.6 0.9 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EMD64565.1 - 1.4e-26 93.2 0.0 3.1e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase RTA1 PF04479.8 EMD64566.1 - 1.4e-45 155.4 3.3 1.8e-45 155.1 2.3 1.1 1 0 0 1 1 1 1 RTA1 like protein AgrB PF04647.10 EMD64566.1 - 0.32 10.0 8.6 5.6 5.9 0.0 3.5 3 0 0 3 3 3 0 Accessory gene regulator B 7TM_GPCR_Srh PF10318.4 EMD64566.1 - 0.4 9.4 8.7 0.13 11.0 0.4 2.5 2 2 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh zf-UBP PF02148.14 EMD64567.1 - 0.084 12.9 0.2 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF3425 PF11905.3 EMD64568.1 - 3.5e-22 78.7 2.8 7.7e-22 77.6 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.13 EMD64568.1 - 1.2e-08 34.7 7.9 2e-08 33.9 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF433 PF04255.9 EMD64568.1 - 0.17 11.3 0.0 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DnaJ PF00226.26 EMD64569.1 - 1.2e-10 40.9 0.3 1.3e-10 40.8 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain Glyoxalase_3 PF13468.1 EMD64570.1 - 8.1e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMD64570.1 - 0.003 17.5 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-C2H2 PF00096.21 EMD64571.1 - 0.037 14.3 0.4 0.037 14.3 0.3 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMD64571.1 - 2.1 8.4 6.1 3 8.0 0.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Thiolase_C PF02803.13 EMD64572.1 - 1.2e-11 44.1 1.3 8.9e-11 41.2 0.3 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMD64572.1 - 1.3e-07 31.1 0.0 2.1e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EMD64572.1 - 1.8e-05 24.3 0.3 6.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EMD64572.1 - 6.8e-05 21.9 0.1 0.0026 16.7 0.0 2.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMD64572.1 - 0.0071 16.1 0.1 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.3 EMD64572.1 - 0.03 14.4 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) SpoVAD PF07451.6 EMD64572.1 - 0.062 11.7 0.2 0.36 9.2 0.0 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) GMC_oxred_N PF00732.14 EMD64573.1 - 4.4e-33 114.7 0.0 6.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD64573.1 - 8.4e-18 65.0 0.6 1.7e-17 64.0 0.4 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EMD64573.1 - 3e-13 49.1 5.9 6.7e-13 48.0 4.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 EMD64573.1 - 7.4e-07 28.3 3.0 0.00065 18.6 1.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD64573.1 - 3e-05 23.0 2.8 0.011 14.6 0.6 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD64573.1 - 5.7e-05 23.0 1.7 0.004 17.0 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD64573.1 - 0.00053 19.1 4.9 0.0024 17.0 1.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD64573.1 - 0.00074 18.0 1.0 0.00074 18.0 0.7 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMD64573.1 - 0.0099 15.9 0.3 1.7 8.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD64573.1 - 0.012 14.5 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EMD64573.1 - 0.065 12.3 0.2 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMD64573.1 - 0.083 11.7 0.1 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD64573.1 - 0.54 10.3 6.7 0.1 12.6 0.9 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF605 PF04652.11 EMD64573.1 - 3.1 7.1 15.2 5.2 6.3 10.5 1.3 1 0 0 1 1 1 0 Vta1 like ParA PF10609.4 EMD64574.1 - 1.2e-32 111.5 0.3 2.6e-31 107.3 0.1 2.5 2 1 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMD64574.1 - 8.2e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMD64574.1 - 5.5e-10 39.3 0.0 3.3e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EMD64574.1 - 4.6e-06 25.9 0.0 6.5e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EMD64574.1 - 8.9e-05 21.6 0.4 0.0047 16.0 0.2 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EMD64574.1 - 0.00023 20.4 0.0 0.6 9.2 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EMD64574.1 - 0.00027 20.5 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD64574.1 - 0.0062 15.9 0.2 0.017 14.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EMD64574.1 - 0.094 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein VirC1 PF07015.6 EMD64574.1 - 0.099 11.7 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein TRAUB PF08164.7 EMD64575.1 - 4.6e-31 106.7 1.3 1.2e-30 105.4 0.1 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EMD64575.1 - 1.5e-28 99.5 2.0 1.5e-28 99.5 1.4 2.7 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor FAD_binding_6 PF00970.19 EMD64577.1 - 3.9e-31 107.0 0.0 9e-31 105.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMD64577.1 - 1.1e-27 96.7 0.0 2.2e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EMD64577.1 - 2.4e-22 78.5 0.1 5.7e-22 77.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_9 PF08021.6 EMD64577.1 - 1.1e-07 31.7 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 EMD64577.1 - 4.5e-06 26.6 0.0 3.6e-05 23.7 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain p450 PF00067.17 EMD64578.1 - 2.2e-60 204.5 0.0 2.8e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EMD64580.1 - 1.2e-44 152.1 0.1 2.1e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMD64580.1 - 2.1e-26 92.2 0.1 5.5e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme AAA_33 PF13671.1 EMD64580.1 - 7.1e-11 42.1 0.1 4.4e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Epimerase PF01370.16 EMD64580.1 - 9.9e-10 38.2 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_18 PF13238.1 EMD64580.1 - 6e-09 36.2 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD64580.1 - 2e-08 35.0 0.0 7.1e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain PP-binding PF00550.20 EMD64580.1 - 6e-08 32.8 0.0 2.2e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site SKI PF01202.17 EMD64580.1 - 5.7e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase AAA_29 PF13555.1 EMD64580.1 - 0.001 18.5 0.3 0.0036 16.7 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD64580.1 - 0.0013 18.8 0.1 0.0098 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMD64580.1 - 0.0013 17.8 0.0 0.0055 15.8 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin adh_short PF00106.20 EMD64580.1 - 0.0037 17.2 0.8 0.029 14.2 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ABC_tran PF00005.22 EMD64580.1 - 0.0047 17.2 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter KTI12 PF08433.5 EMD64580.1 - 0.0048 16.1 0.0 0.013 14.7 0.0 1.8 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EMD64580.1 - 0.0055 16.6 0.1 0.027 14.4 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 EMD64580.1 - 0.0074 16.4 0.1 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 3Beta_HSD PF01073.14 EMD64580.1 - 0.01 14.5 0.1 0.035 12.8 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMD64580.1 - 0.012 15.2 0.9 0.045 13.4 0.1 2.4 3 0 0 3 3 2 0 KR domain AAA_25 PF13481.1 EMD64580.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EMD64580.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 EMD64580.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EMD64580.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMD64580.1 - 0.069 12.0 0.1 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.1 EMD64580.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMD64580.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EMD64581.1 - 3.9e-18 65.2 9.5 4.8e-18 64.9 6.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.1 EMD64581.1 - 0.00072 19.5 1.0 0.0012 18.7 0.7 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AB Fungal_trans PF04082.13 EMD64582.1 - 9.9e-28 96.7 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64582.1 - 9.8e-08 31.7 10.1 2.6e-07 30.4 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EMD64583.1 - 9e-48 162.5 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 EMD64584.1 - 1.4e-06 28.5 2.1 0.0015 18.6 0.0 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) GNAT_acetyltr_2 PF13718.1 EMD64584.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Amidohydro_2 PF04909.9 EMD64587.1 - 4.2e-08 33.0 0.0 4.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EMD64588.1 - 1.5e-16 60.0 0.1 1.6e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fig1 PF12351.3 EMD64589.1 - 0.043 13.6 0.4 0.043 13.6 0.3 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Glyco_tranf_2_3 PF13641.1 EMD64590.1 - 2.5e-32 112.5 0.0 3.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD64590.1 - 2.2e-15 56.8 0.5 5.9e-15 55.4 0.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMD64590.1 - 3.2e-14 52.9 0.0 5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD64590.1 - 1.2e-10 40.9 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EMD64590.1 - 3.7e-08 32.1 0.2 0.008 14.5 0.1 3.1 1 1 2 3 3 3 3 Cellulose synthase ubiquitin PF00240.18 EMD64591.1 - 7.4e-17 60.5 0.0 1.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMD64591.1 - 8.2e-09 35.0 0.0 1.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Plexin_cytopl PF08337.7 EMD64591.1 - 0.19 9.9 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Tyrosinase PF00264.15 EMD64592.1 - 1.7e-21 77.4 2.5 4.2e-21 76.1 1.7 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase SBF PF01758.11 EMD64593.1 - 1.1e-47 161.8 14.0 1.1e-47 161.8 9.7 2.3 3 1 0 3 3 3 1 Sodium Bile acid symporter family MFS_1 PF07690.11 EMD64593.1 - 0.61 8.7 34.4 11 4.6 5.3 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily Rhodanese PF00581.15 EMD64594.1 - 6.6e-06 26.4 0.0 1.3e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.10 EMD64595.1 - 1.1e-11 44.4 0.0 5.4e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 NADPH-dependent FMN reductase DUF3328 PF11807.3 EMD64597.1 - 1.2e-18 67.6 0.8 1.3e-18 67.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MAR_sialic_bdg PF10564.4 EMD64597.1 - 0.13 12.0 0.1 0.2 11.4 0.0 1.3 1 1 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat DUF3328 PF11807.3 EMD64598.1 - 0.00064 19.4 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ATG27 PF09451.5 EMD64598.1 - 0.15 11.2 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3328 PF11807.3 EMD64599.1 - 8.6e-37 126.9 0.6 9.6e-37 126.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy PF03171.15 EMD64600.1 - 0.00033 20.8 0.0 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMD64600.1 - 0.0066 16.9 0.1 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMD64600.1 - 0.0085 15.7 0.8 0.028 14.0 0.5 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 EMD64601.1 - 1.2e-24 87.2 1.0 2.5e-24 86.1 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Sec62 PF03839.11 EMD64602.1 - 0.0014 18.0 5.5 0.0051 16.2 1.6 2.7 3 0 0 3 3 3 1 Translocation protein Sec62 KH_1 PF00013.24 EMD64602.1 - 0.013 15.1 0.1 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 KH domain 7tm_7 PF08395.7 EMD64602.1 - 6.4 5.6 10.5 0.13 11.2 0.7 2.2 2 1 0 2 2 2 0 7tm Chemosensory receptor Lon_C PF05362.8 EMD64605.1 - 8.3e-66 221.1 0.0 1.6e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMD64605.1 - 2.3e-34 118.8 0.0 5.2e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMD64605.1 - 5.9e-22 78.2 0.0 1.5e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EMD64605.1 - 3.9e-08 32.8 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EMD64605.1 - 1.2e-07 31.7 0.0 3.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMD64605.1 - 4e-07 29.8 0.0 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMD64605.1 - 1.3e-05 25.9 0.1 9.2e-05 23.2 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EMD64605.1 - 2.5e-05 24.4 0.1 0.0021 18.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EMD64605.1 - 3e-05 22.9 0.0 5.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 EMD64605.1 - 5.3e-05 23.2 0.3 0.00026 21.0 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 EMD64605.1 - 0.00018 20.6 0.0 0.001 18.1 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMD64605.1 - 0.0028 17.5 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD64605.1 - 0.0085 16.3 0.0 0.0085 16.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.10 EMD64605.1 - 0.0086 15.7 0.1 0.061 13.0 0.0 2.2 1 1 1 2 2 2 1 NTPase IstB_IS21 PF01695.12 EMD64605.1 - 0.0098 15.3 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMD64605.1 - 0.027 14.4 0.0 7.5 6.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMD64605.1 - 0.035 14.2 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 EMD64605.1 - 0.04 13.4 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EMD64605.1 - 0.054 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMD64605.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMD64605.1 - 0.067 12.9 0.5 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EMD64605.1 - 0.071 13.4 0.4 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EMD64605.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 EMD64607.1 - 9.4e-15 54.4 0.0 8.9e-10 38.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64607.1 - 3e-13 49.4 0.0 2.2e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3328 PF11807.3 EMD64609.1 - 4.7e-34 117.9 0.2 5.5e-34 117.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PIG-P PF08510.7 EMD64610.1 - 0.032 13.8 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 PIG-P Aconitase_C PF00694.14 EMD64610.1 - 0.15 12.1 0.9 24 5.0 0.1 2.9 1 1 1 2 2 2 0 Aconitase C-terminal domain TPR_10 PF13374.1 EMD64611.1 - 1e-07 31.6 3.0 3.7e-07 29.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD64611.1 - 1.6e-05 24.7 1.2 5.2e-05 23.0 0.0 2.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD64611.1 - 0.003 16.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_4 PF07721.9 EMD64611.1 - 0.012 15.9 0.2 0.012 15.9 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD64611.1 - 0.032 14.0 0.6 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64611.1 - 0.21 12.3 2.3 0.5 11.1 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Herpes_UL87 PF03043.9 EMD64614.1 - 0.053 11.9 0.0 0.15 10.3 0.0 1.6 1 1 0 1 1 1 0 Herpesvirus UL87 family MIP-T3 PF10243.4 EMD64614.1 - 1.5 7.2 79.0 0.057 11.8 32.7 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF1675 PF07897.6 EMD64614.1 - 2.5 7.9 38.2 0.44 10.3 12.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF572 PF04502.8 EMD64614.1 - 3.5 6.7 48.6 0.1 11.8 7.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4045 PF13254.1 EMD64614.1 - 4.5 6.4 48.0 0.81 8.9 16.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) TFIIF_alpha PF05793.7 EMD64614.1 - 6.7 4.9 47.8 0.83 7.9 21.8 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 EMD64614.1 - 8.1 4.4 62.5 1.2 7.2 24.6 2.0 2 0 0 2 2 2 0 Utp14 protein HET PF06985.6 EMD64615.1 - 5.4e-23 81.6 0.1 6.5e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.19 EMD64616.1 - 1.6e-08 34.4 0.2 3.8e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD64616.1 - 1.2e-07 31.7 0.0 8.3e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD64616.1 - 0.00015 21.8 0.1 0.37 10.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD64616.1 - 0.0045 16.8 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1212 PF06738.7 EMD64617.1 - 5.6e-48 162.9 4.2 5.6e-48 162.9 2.9 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMD64617.1 - 1.2e-24 86.6 15.9 1.2e-24 86.6 11.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) bZIP_1 PF00170.16 EMD64620.1 - 1.9e-07 30.9 6.6 4e-07 29.8 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Adeno_PIX PF03955.9 EMD64620.1 - 0.006 17.0 0.6 0.011 16.1 0.4 1.4 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 EMD64620.1 - 0.0095 16.2 7.0 0.0095 16.2 4.8 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EMD64620.1 - 0.015 15.0 10.5 0.044 13.6 7.3 1.7 1 1 0 1 1 1 0 Basic region leucine zipper AATF-Che1 PF13339.1 EMD64620.1 - 0.23 11.6 3.5 0.33 11.1 2.4 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Epiglycanin_C PF14654.1 EMD64624.1 - 0.18 11.8 1.8 0.18 11.8 0.3 1.7 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region AAA_assoc PF14363.1 EMD64625.1 - 0.039 14.0 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Domain associated at C-terminal with AAA Coatomer_WDAD PF04053.9 EMD64626.1 - 9.9e-171 568.3 0.0 2e-170 567.4 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EMD64626.1 - 2.7e-44 147.5 6.0 3.4e-10 39.3 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD64626.1 - 0.00025 20.7 0.0 0.53 10.0 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EMD64626.1 - 0.00053 18.2 2.5 0.028 12.5 0.1 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EMD64626.1 - 0.05 13.3 0.0 6 6.5 0.0 3.5 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.8 EMD64626.1 - 0.3 10.9 7.9 0.41 10.4 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.24 EMD64627.1 - 1.2e-36 125.7 0.0 3.6e-36 124.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMD64627.1 - 1.3e-05 25.0 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD64627.1 - 2.4e-05 25.1 0.1 9.6e-05 23.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EMD64627.1 - 2.8e-05 24.2 0.1 0.00063 19.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD64627.1 - 3.7e-05 22.8 0.0 6.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EMD64627.1 - 5.3e-05 22.7 0.1 0.037 13.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD64627.1 - 6.3e-05 23.0 1.6 0.00059 19.8 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMD64627.1 - 6.5e-05 22.6 0.1 0.00049 19.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMD64627.1 - 8.1e-05 22.5 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMD64627.1 - 0.00017 21.0 0.0 0.00049 19.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMD64627.1 - 0.00018 21.4 1.0 0.0081 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD64627.1 - 0.00073 19.4 0.0 0.00073 19.4 0.0 2.0 3 0 0 3 3 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMD64627.1 - 0.00091 19.2 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EMD64627.1 - 0.001 18.2 0.1 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMD64627.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.9 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 EMD64627.1 - 0.0029 17.2 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EMD64627.1 - 0.0047 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EMD64627.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD64627.1 - 0.0082 16.4 0.9 0.019 15.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EMD64627.1 - 0.0092 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain PGA2 PF07543.7 EMD64627.1 - 0.015 15.0 9.0 0.079 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Parvo_NS1 PF01057.12 EMD64627.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EMD64627.1 - 0.026 14.0 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EMD64627.1 - 0.028 13.9 0.6 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMD64627.1 - 0.033 14.4 0.8 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 EMD64627.1 - 0.05 12.5 0.0 0.12 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 EMD64627.1 - 0.06 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EMD64627.1 - 0.07 11.7 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EMD64627.1 - 0.087 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EMD64627.1 - 0.089 12.4 0.0 0.28 10.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EMD64627.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 EMD64627.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.0 4 0 0 4 4 3 0 Shikimate kinase TIM21 PF08294.6 EMD64628.1 - 1.2e-40 138.4 0.0 1.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EMD64628.1 - 2e-09 36.9 0.0 3.9e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Syntaxin-18_N PF10496.4 EMD64630.1 - 1.1e-16 60.4 0.9 1.1e-16 60.4 0.6 2.4 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EMD64630.1 - 0.00011 21.8 4.9 0.00013 21.5 1.8 2.5 2 0 0 2 2 2 1 SNARE domain TORC_N PF12884.2 EMD64630.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.1 3 2 0 3 3 3 0 Transducer of regulated CREB activity, N terminus FAM181 PF15238.1 EMD64630.1 - 1.8 8.5 9.6 2.9 7.8 2.1 2.5 2 1 0 2 2 2 0 FAM181 DUF4239 PF14023.1 EMD64630.1 - 4.7 6.5 8.6 1.5 8.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Aminotran_1_2 PF00155.16 EMD64631.1 - 5.9e-84 282.0 0.0 6.8e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UBN2_3 PF14244.1 EMD64632.1 - 1e-05 25.1 0.0 8.9e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EMD64632.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EMD64632.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ACPS PF01648.15 EMD64633.1 - 1.3e-11 44.3 0.1 9e-11 41.6 0.1 2.0 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF3433 PF11915.3 EMD64634.1 - 4.8e-18 65.1 3.1 4.8e-18 65.1 2.1 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3433) MGC-24 PF05283.6 EMD64635.1 - 0.21 11.3 6.5 0.46 10.2 4.5 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) FKBP_C PF00254.23 EMD64637.1 - 5.3e-20 71.2 0.0 6.2e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 EMD64638.1 - 2.3e-16 60.0 0.1 5e-16 58.9 0.0 1.5 2 0 0 2 2 2 1 PHP domain AIG2_2 PF13772.1 EMD64639.1 - 1.2e-06 28.5 0.1 1.4e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EMD64639.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family BAR_2 PF10455.4 EMD64640.1 - 8e-63 212.0 0.3 1.2e-62 211.5 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EMD64640.1 - 4.4e-18 65.6 1.3 2.8e-17 62.9 0.9 1.9 1 1 0 1 1 1 1 BAR domain zf-C4H2 PF10146.4 EMD64640.1 - 0.59 10.1 5.4 0.19 11.6 0.8 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Zn_clus PF00172.13 EMD64641.1 - 7.2e-08 32.2 10.2 1.2e-07 31.5 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD64641.1 - 0.00011 20.9 0.2 0.0002 20.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ebola_NP PF05505.7 EMD64641.1 - 0.85 7.6 7.0 1.4 6.9 4.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 EMD64641.1 - 2.4 6.0 6.7 3.3 5.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RING_2 PF13639.1 EMD64643.1 - 7.6e-13 48.0 8.0 1.2e-12 47.4 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD64643.1 - 1.3e-08 34.8 2.8 2.1e-08 34.1 1.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD64643.1 - 1.1e-06 28.5 8.3 1.7e-06 27.9 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD64643.1 - 3.7e-05 23.2 8.5 5.6e-05 22.7 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD64643.1 - 4.5e-05 23.0 6.6 6.7e-05 22.5 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMD64643.1 - 4.8e-05 23.1 3.0 8.2e-05 22.3 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EMD64643.1 - 0.001 18.6 4.8 0.0017 18.0 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EMD64643.1 - 0.14 12.2 9.4 0.21 11.6 6.5 1.3 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMD64643.1 - 0.26 11.2 5.1 0.48 10.4 3.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMD64643.1 - 0.29 10.7 7.1 0.47 10.0 4.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMD64643.1 - 0.36 10.5 3.7 0.72 9.6 2.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EMD64643.1 - 0.55 10.2 4.5 0.93 9.5 3.1 1.3 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EMD64643.1 - 0.72 9.4 3.8 1.3 8.6 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SR-25 PF10500.4 EMD64643.1 - 5.8 6.3 6.9 13 5.1 4.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_I_TF PF04090.7 EMD64644.1 - 2.1e-10 40.1 0.0 1.6e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_2 PF07719.12 EMD64644.1 - 0.32 10.9 2.5 38 4.5 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Shisa PF13908.1 EMD64644.1 - 5.8 7.0 6.2 6 7.0 3.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAD_binding_3 PF01494.14 EMD64645.1 - 1.7e-93 313.5 0.0 2.2e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMD64645.1 - 7.4e-45 152.5 0.0 1.3e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EMD64645.1 - 0.0003 19.3 0.2 0.00043 18.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EMD64645.1 - 0.00048 19.0 0.2 0.00084 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD64645.1 - 0.0005 20.0 0.2 0.0029 17.4 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD64645.1 - 0.0012 17.8 0.0 0.14 11.0 0.0 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD64645.1 - 0.005 15.8 0.1 0.0092 14.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD64645.1 - 0.025 14.6 0.0 0.56 10.2 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD64645.1 - 0.028 13.5 0.1 0.069 12.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EMD64645.1 - 0.074 13.1 0.1 0.37 10.8 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD64645.1 - 0.18 10.6 0.2 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 EMD64645.1 - 0.19 10.4 0.0 2.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EMD64645.1 - 0.26 9.8 1.2 4.7 5.7 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Chitin_synth_1 PF01644.12 EMD64646.1 - 6.1e-84 279.7 0.1 9.5e-84 279.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMD64646.1 - 7.5e-31 105.6 0.1 1.6e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMD64646.1 - 1.2e-22 80.0 0.3 7.6e-20 70.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMD64646.1 - 1.9e-08 34.2 0.7 1.9e-08 34.2 0.5 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD64646.1 - 2.8e-05 24.0 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Csm1 PF12539.3 EMD64647.1 - 1.2e-23 83.4 0.0 2.6e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 APG6 PF04111.7 EMD64647.1 - 0.0059 15.6 12.2 0.0059 15.6 8.5 1.6 2 0 0 2 2 1 1 Autophagy protein Apg6 GAS PF13851.1 EMD64647.1 - 0.0076 15.4 14.7 0.075 12.2 7.5 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EMD64647.1 - 0.013 15.8 4.3 0.013 15.8 3.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HAUS-augmin3 PF14932.1 EMD64647.1 - 0.021 14.0 12.6 0.044 12.9 8.8 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Trypan_PARP PF05887.6 EMD64647.1 - 0.85 9.4 35.1 0.47 10.2 10.4 2.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Reo_sigmaC PF04582.7 EMD64647.1 - 1 8.4 7.0 1.7 7.7 4.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EMD64647.1 - 1.7 8.2 15.9 3.1 7.3 9.0 2.4 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 EMD64647.1 - 1.9 7.0 11.8 3.6 6.1 8.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EMD64647.1 - 2.1 8.6 5.8 36 4.6 2.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EMD64647.1 - 3.9 7.0 10.9 0.34 10.4 2.1 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF904 PF06005.7 EMD64647.1 - 7.2 6.9 9.8 5.9 7.2 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2611 PF11022.3 EMD64648.1 - 2.6e-28 97.9 0.4 2.8e-28 97.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 EMD64649.1 - 2e-67 225.7 0.0 2.7e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DEAD PF00270.24 EMD64650.1 - 9e-20 70.8 0.0 1.7e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD64650.1 - 1.2e-19 69.9 0.0 1.9e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMD64650.1 - 0.0048 16.7 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMD64650.1 - 0.041 12.6 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain HATPase_c PF02518.21 EMD64651.1 - 3.5e-22 78.2 0.0 7.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD64651.1 - 2.3e-19 69.4 0.6 1.6e-11 44.2 0.2 3.3 3 1 0 3 3 3 2 Response regulator receiver domain PAS_9 PF13426.1 EMD64651.1 - 1.1e-16 61.0 0.0 2.4e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EMD64651.1 - 1e-15 57.5 0.0 3.2e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EMD64651.1 - 7.3e-14 51.7 0.0 5.1e-06 26.4 0.0 4.0 6 0 0 6 6 6 2 PAS fold PAS PF00989.19 EMD64651.1 - 4.3e-10 39.3 0.0 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 EMD64651.1 - 5.5e-07 29.4 0.8 2.1e-06 27.6 0.2 2.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 EMD64651.1 - 0.00011 21.9 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 2 PAS domain HATPase_c_3 PF13589.1 EMD64651.1 - 0.089 12.4 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E7 PF00527.13 EMD64651.1 - 0.09 12.9 0.7 2 8.5 0.0 2.6 2 0 0 2 2 2 0 E7 protein, Early protein HET PF06985.6 EMD64653.1 - 9.4e-39 132.7 3.5 1.2e-38 132.4 2.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 EMD64653.1 - 0.06 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) zf-AN1 PF01428.11 EMD64654.1 - 9e-24 83.0 20.1 1.6e-12 47.0 4.3 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EMD64654.1 - 0.012 15.8 14.9 0.32 11.2 2.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.16 EMD64654.1 - 0.016 15.0 4.1 0.016 15.0 2.9 2.6 2 1 0 2 2 2 0 IBR domain DUF3816 PF12822.2 EMD64656.1 - 4.4 7.1 10.3 0.18 11.6 3.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) TruB_N PF01509.13 EMD64657.1 - 3.6e-39 134.2 0.0 7.2e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) zf-C2H2_4 PF13894.1 EMD64658.1 - 6.7e-06 26.0 23.5 0.058 13.7 2.8 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD64658.1 - 0.0009 19.4 19.6 0.38 11.1 0.7 5.1 3 1 1 4 4 4 2 Zinc finger, C2H2 type DUF4648 PF15505.1 EMD64658.1 - 0.014 15.6 0.2 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) BIR PF00653.16 EMD64658.1 - 0.092 13.1 3.2 5 7.6 0.0 2.7 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain DUF2946 PF11162.3 EMD64658.1 - 4.7 7.4 8.7 2.6e+02 1.8 6.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) ketoacyl-synt PF00109.21 EMD64659.1 - 4e-52 177.2 0.0 5.5e-46 157.1 0.0 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMD64659.1 - 3.2e-33 114.0 0.2 1.4e-32 112.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMD64659.1 - 1.4e-06 27.5 0.1 3.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EMD64659.1 - 1.8e-05 24.9 0.9 6.9e-05 23.0 0.6 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 EMD64659.1 - 0.062 12.6 0.1 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Acyl transferase domain Dpoe2NT PF12213.3 EMD64660.1 - 0.015 15.2 0.2 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal DUF2433 PF10360.4 EMD64660.1 - 0.018 15.3 0.1 0.074 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) Polysacc_deac_1 PF01522.16 EMD64661.1 - 4.5e-31 107.0 0.0 7.2e-31 106.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMD64661.1 - 1.9e-15 56.5 85.5 2.4e-06 27.4 16.5 3.8 4 0 0 4 4 4 3 Chitin recognition protein Glyco_hydro_57 PF03065.10 EMD64661.1 - 0.081 11.8 0.0 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DUF932 PF06067.6 EMD64661.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Aminotran_1_2 PF00155.16 EMD64662.1 - 3.5e-36 124.9 0.0 5.7e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Rad4 PF03835.10 EMD64662.1 - 8.8e-33 112.7 0.1 8.8e-33 112.7 0.1 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMD64662.1 - 2.7e-30 103.9 0.1 5.7e-30 102.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EMD64662.1 - 1e-17 64.1 0.7 1e-17 64.1 0.5 3.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EMD64662.1 - 4e-17 61.4 0.6 8.3e-17 60.4 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Beta_elim_lyase PF01212.16 EMD64662.1 - 0.0043 16.2 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C2H2 PF00096.21 EMD64663.1 - 4.3e-12 45.5 17.6 0.00012 22.2 0.9 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD64663.1 - 3.4e-07 30.2 1.6 3.4e-07 30.2 1.1 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD64663.1 - 1.9e-06 27.7 17.6 0.027 14.7 1.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMD64663.1 - 5.2e-05 23.0 1.0 0.0029 17.4 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger CpXC PF14353.1 EMD64663.1 - 0.11 12.4 0.5 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 CpXC protein zf-Di19 PF05605.7 EMD64663.1 - 0.47 10.6 9.5 0.25 11.4 2.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EMD64663.1 - 0.48 10.4 3.5 0.19 11.7 0.4 1.9 2 0 0 2 2 2 0 zinc-finger DUF1936 PF09151.5 EMD64663.1 - 0.64 9.5 7.3 1.1 8.8 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) Zn-ribbon_8 PF09723.5 EMD64663.1 - 5.6 6.9 7.4 3.4 7.7 2.4 2.6 2 1 0 2 2 2 0 Zinc ribbon domain FAD_binding_4 PF01565.18 EMD64664.1 - 4.2e-29 100.8 0.6 7.5e-29 99.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD64664.1 - 0.0061 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HlyD PF00529.15 EMD64665.1 - 0.18 11.1 26.5 0.27 10.4 18.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein MIP-T3 PF10243.4 EMD64665.1 - 0.45 8.9 60.8 0.73 8.2 42.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mit_ribos_Mrp51 PF11709.3 EMD64667.1 - 1.6e-63 214.8 0.3 2.5e-63 214.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit RPAP2_Rtr1 PF04181.8 EMD64668.1 - 3.6e-18 65.4 0.1 6.3e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.1 EMD64669.1 - 1.6e-10 40.3 0.3 3.4e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMD64669.1 - 2e-10 39.8 0.2 4.5e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD64669.1 - 6.1e-10 38.4 0.1 1.2e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EMD64670.1 - 9.7e-38 129.7 44.8 9.7e-38 129.7 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64670.1 - 9.9e-09 34.2 35.9 3.9e-07 28.9 24.4 3.2 1 1 1 2 2 2 1 Sugar (and other) transporter PMP1_2 PF08114.6 EMD64670.1 - 0.012 15.0 1.1 0.029 13.8 0.0 2.2 2 0 0 2 2 2 0 ATPase proteolipid family Ribosomal_L29 PF00831.18 EMD64671.1 - 0.038 13.6 0.2 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein peroxidase PF00141.18 EMD64672.1 - 1.6e-30 106.2 0.2 2.3e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Peroxidase GFA PF04828.9 EMD64674.1 - 8e-20 70.5 5.2 1e-08 35.0 0.2 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EMD64674.1 - 0.099 12.5 2.3 11 5.9 0.0 3.1 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase_Tyr PF07714.12 EMD64675.1 - 3.6e-05 22.9 0.0 5.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMD64675.1 - 6.5e-05 22.1 0.0 9.9e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1077 PF06417.7 EMD64676.1 - 1.2e-45 153.8 0.2 1.6e-45 153.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EMD64677.1 - 2.6e-132 441.8 10.8 3.3e-132 441.5 7.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMD64677.1 - 1.7e-19 70.3 4.2 2.6e-19 69.7 0.2 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMD64677.1 - 8.2e-14 51.6 4.3 2.1e-09 37.5 0.1 4.2 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EMD64677.1 - 1.5e-12 46.4 0.5 0.00027 20.7 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EMD64677.1 - 2.7e-05 24.4 1.7 0.0056 17.1 0.0 4.9 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EMD64677.1 - 4.5e-05 22.9 2.9 0.025 13.9 0.0 3.8 4 1 1 5 5 5 2 CLASP N terminal Arm PF00514.18 EMD64677.1 - 0.00015 21.4 1.7 2.1 8.2 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EMD64677.1 - 0.0052 16.4 0.1 3.7 7.3 0.0 4.0 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF2496 PF10689.4 EMD64677.1 - 0.026 14.1 0.1 0.092 12.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) T_hemolysin PF12261.3 EMD64677.1 - 0.083 12.4 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Thermostable hemolysin DUF1774 PF08611.5 EMD64678.1 - 4.3e-29 100.5 0.1 4.3e-29 100.5 0.0 2.8 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1774) Na_Pi_cotrans PF02690.10 EMD64678.1 - 0.27 10.9 6.5 0.1 12.3 2.6 1.8 1 1 0 1 1 1 0 Na+/Pi-cotransporter DUF788 PF05620.6 EMD64678.1 - 8.5 6.2 8.0 4 7.2 1.5 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF788) Hist_deacetyl PF00850.14 EMD64679.1 - 5.5e-62 209.8 0.2 8.4e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Macoilin PF09726.4 EMD64680.1 - 0.0065 14.8 0.3 0.008 14.5 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF4298 PF14131.1 EMD64680.1 - 0.009 15.8 1.3 0.018 14.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4298) DMPK_coil PF08826.5 EMD64680.1 - 0.02 14.7 0.3 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like TMF_TATA_bd PF12325.3 EMD64680.1 - 0.02 14.5 0.8 0.033 13.9 0.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Dynamitin PF04912.9 EMD64680.1 - 0.032 13.0 0.5 0.039 12.7 0.3 1.1 1 0 0 1 1 1 0 Dynamitin Cdc6_C PF09079.6 EMD64680.1 - 0.036 13.7 0.3 0.062 13.0 0.2 1.4 1 0 0 1 1 1 0 CDC6, C terminal FAD_binding_1 PF00667.15 EMD64680.1 - 0.04 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain V_ATPase_I PF01496.14 EMD64680.1 - 0.16 9.7 0.5 0.18 9.6 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4253 PF14062.1 EMD64681.1 - 0.062 12.9 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Integrase_AP2 PF14657.1 EMD64681.1 - 0.077 12.7 0.2 0.18 11.5 0.1 1.6 1 1 0 1 1 1 0 AP2-like DNA-binding integrase domain DUF1490 PF07371.7 EMD64681.1 - 0.079 12.9 0.4 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) Nif11 PF07862.6 EMD64681.1 - 0.13 12.1 0.0 0.44 10.5 0.0 1.9 1 1 0 1 1 1 0 Nitrogen fixation protein of unknown function Sigma_reg_N PF13800.1 EMD64682.1 - 0.005 16.8 0.4 0.043 13.8 0.2 2.0 2 0 0 2 2 2 1 Sigma factor regulator N-terminal Sarcoglycan_2 PF05510.8 EMD64682.1 - 0.069 11.4 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Ribosomal_S17e PF00833.13 EMD64683.1 - 2e-58 195.4 0.5 2.5e-58 195.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EMD64683.1 - 0.0042 17.7 0.4 0.006 17.2 0.2 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal Na_Ca_ex PF01699.19 EMD64684.1 - 9.3e-26 90.0 21.0 5.8e-14 51.8 5.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GerA PF03323.8 EMD64684.1 - 0.0049 15.0 0.4 0.0092 14.1 0.3 1.4 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein N_methyl_2 PF13544.1 EMD64684.1 - 0.013 14.9 0.0 0.013 14.9 0.0 3.2 4 0 0 4 4 4 0 Type IV pilin N-term methylation site GFxxxE Peptidase_M28 PF04389.12 EMD64685.1 - 2.4e-33 115.3 0.0 3.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMD64685.1 - 6.2e-16 57.9 0.1 6.6e-15 54.6 0.0 2.2 1 1 1 2 2 2 2 PA domain Peptidase_M20 PF01546.23 EMD64685.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FAD_binding_3 PF01494.14 EMD64686.1 - 3.9e-19 68.9 0.0 5.3e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD64686.1 - 2.8e-05 24.4 0.0 0.45 10.9 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD64686.1 - 0.0021 17.0 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD64686.1 - 0.0037 17.3 0.0 0.0095 16.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EMD64686.1 - 0.0089 14.2 0.0 0.62 8.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 EMD64686.1 - 0.036 14.1 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TGT PF01702.13 EMD64687.1 - 3.1e-89 298.3 0.0 3.8e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans PF04082.13 EMD64689.1 - 0.1 11.4 0.4 0.18 10.6 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD64691.1 - 5.5e-39 133.8 16.3 5.6e-30 104.2 0.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64691.1 - 5.5e-12 44.9 13.2 5.5e-12 44.9 9.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Toxin_39 PF15500.1 EMD64691.1 - 0.089 12.9 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin AFG1_ATPase PF03969.11 EMD64692.1 - 3.4e-89 299.1 0.0 2.5e-84 283.1 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase zf-DHHC PF01529.15 EMD64692.1 - 5.5e-38 130.0 6.1 1.2e-37 128.9 4.2 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.25 EMD64692.1 - 1e-33 113.4 4.6 2.2e-08 33.4 0.2 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EMD64692.1 - 1.7e-30 105.1 0.0 2.3e-15 56.7 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD64692.1 - 1.4e-26 92.3 4.0 4.7e-08 33.3 0.2 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD64692.1 - 2.9e-26 90.9 4.1 2.4e-08 33.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64692.1 - 2.2e-20 70.6 6.2 4.8e-07 29.3 0.2 6.2 6 0 0 6 6 6 4 Ankyrin repeat AAA_16 PF13191.1 EMD64692.1 - 0.097 12.6 0.0 21 5.0 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EMD64693.1 - 6.1e-46 156.1 0.1 6e-28 97.8 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMD64693.1 - 4.4e-35 121.4 22.9 6.3e-20 71.7 8.2 4.2 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EMD64693.1 - 3.4e-14 52.6 0.5 3e-07 29.8 0.8 4.3 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD64693.1 - 4e-12 46.6 0.1 0.0086 16.0 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EMD64693.1 - 5.6e-08 32.4 0.0 0.0001 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD64693.1 - 1.8e-07 31.3 1.0 0.01 15.8 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EMD64693.1 - 3.7e-07 30.6 0.1 0.00075 19.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD64693.1 - 3.8e-06 27.0 0.0 0.2 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMD64693.1 - 1.3e-05 24.5 0.6 0.0029 17.0 0.2 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain T2SE PF00437.15 EMD64693.1 - 2.4e-05 23.4 0.1 0.005 15.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EMD64693.1 - 9.2e-05 22.0 0.1 0.001 18.5 0.1 2.5 2 1 1 3 3 3 1 AAA-like domain DUF87 PF01935.12 EMD64693.1 - 0.00018 21.4 0.7 0.00046 20.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMD64693.1 - 0.0018 17.7 3.4 0.0059 16.1 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EMD64693.1 - 0.0085 16.0 0.0 1.5 8.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 EMD64693.1 - 0.0092 15.6 0.2 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 EMD64693.1 - 0.01 15.7 0.5 16 5.2 0.0 3.8 4 0 0 4 4 4 0 Dynamin family DUF258 PF03193.11 EMD64693.1 - 0.011 14.8 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EMD64693.1 - 0.012 15.3 0.1 0.66 9.6 0.0 3.2 3 1 0 3 3 3 0 Archaeal ATPase Zeta_toxin PF06414.7 EMD64693.1 - 0.02 13.9 0.6 2.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin Miro PF08477.8 EMD64693.1 - 0.023 15.1 0.1 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein Zot PF05707.7 EMD64693.1 - 0.024 14.1 0.1 0.59 9.5 0.0 2.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) GTP_EFTU PF00009.22 EMD64693.1 - 0.032 13.6 0.2 8.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EMD64693.1 - 0.042 13.5 0.8 1.5 8.6 0.1 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EMD64693.1 - 0.093 12.6 0.0 6.8 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EMD64693.1 - 0.096 11.2 0.5 1 7.8 0.0 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class CbiA PF01656.18 EMD64693.1 - 0.12 11.7 0.4 0.29 10.5 0.3 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EMD64693.1 - 0.22 10.9 0.5 11 5.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMD64693.1 - 0.23 11.1 0.4 0.84 9.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T5orf172 PF10544.4 EMD64694.1 - 5.6e-14 52.3 1.9 1.2e-13 51.2 1.3 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EMD64694.1 - 9.7e-12 45.1 2.1 2.5e-11 43.8 1.5 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Tox-URI2 PF15653.1 EMD64694.1 - 0.1 12.7 0.4 0.27 11.4 0.1 1.8 1 1 1 2 2 2 0 URI fold toxin 2 NMO PF03060.10 EMD64695.1 - 6.8e-72 242.3 1.5 8e-72 242.1 1.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMD64695.1 - 7e-07 28.4 0.1 1.1e-05 24.5 0.0 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMD64695.1 - 1.2e-05 24.3 1.6 2e-05 23.6 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EMD64695.1 - 0.0013 17.7 0.5 0.0013 17.7 0.3 1.6 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EMD64695.1 - 0.018 13.9 0.2 0.032 13.1 0.1 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 EMD64695.1 - 0.065 12.2 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Pterin_bind PF00809.17 EMD64696.1 - 3.7e-67 225.7 0.0 6.7e-67 224.9 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EMD64696.1 - 2.6e-35 120.9 0.0 5.5e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) adh_short PF00106.20 EMD64697.1 - 1e-63 214.1 3.5 5.8e-32 110.9 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMD64697.1 - 4.7e-31 107.8 0.6 1.6e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EMD64697.1 - 2.6e-30 104.3 0.0 7.3e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain Epimerase PF01370.16 EMD64697.1 - 0.0096 15.3 2.8 0.047 13.1 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glucodextran_B PF09136.5 EMD64697.1 - 0.018 15.1 0.1 0.071 13.2 0.0 2.0 1 0 0 1 1 1 0 Glucodextranase, domain B DUF4161 PF13722.1 EMD64697.1 - 0.02 15.2 1.0 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) Methyltransf_23 PF13489.1 EMD64698.1 - 2.6e-12 46.7 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD64698.1 - 4.9e-08 33.3 0.0 7.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD64698.1 - 5.1e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD64698.1 - 6e-05 23.5 0.0 0.0003 21.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD64698.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EMD64698.1 - 0.031 14.2 0.0 0.5 10.3 0.0 2.1 1 1 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EMD64698.1 - 0.052 12.9 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EMD64698.1 - 0.059 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EMD64698.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Lipase_GDSL PF00657.17 EMD64701.1 - 1.9e-17 63.8 0.3 2.9e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ORC4_C PF14629.1 EMD64702.1 - 1.2e-49 168.4 0.0 1.9e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EMD64702.1 - 1.6e-17 64.1 0.1 1e-16 61.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD64702.1 - 8.9e-08 32.3 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMD64702.1 - 6.1e-06 26.4 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMD64702.1 - 1.7e-05 24.5 0.3 0.00039 20.1 0.2 2.4 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EMD64702.1 - 2.2e-05 23.5 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EMD64702.1 - 0.00016 20.8 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EMD64702.1 - 0.00041 20.1 0.0 0.00092 18.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase ATP-synt_ab PF00006.20 EMD64702.1 - 0.0098 15.4 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EMD64702.1 - 0.012 15.1 0.6 0.44 9.9 0.2 2.3 1 1 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EMD64702.1 - 0.018 14.5 0.1 0.051 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EMD64702.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EMD64702.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.3 EMD64702.1 - 0.029 12.9 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) FtsK_SpoIIIE PF01580.13 EMD64702.1 - 0.03 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EMD64702.1 - 0.035 14.4 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EMD64702.1 - 0.035 13.5 0.2 0.12 11.7 0.1 1.7 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EMD64702.1 - 0.038 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 EMD64702.1 - 0.097 12.3 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EMD64702.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TrwB_AAD_bind PF10412.4 EMD64702.1 - 0.13 10.8 0.1 0.24 9.9 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 EMD64702.1 - 0.13 11.1 0.1 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase ATP_bind_1 PF03029.12 EMD64702.1 - 0.21 11.0 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 EMD64702.1 - 0.4 9.6 0.2 4.8 6.1 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 EMD64703.1 - 5.2e-17 61.5 50.2 1.9e-11 43.2 13.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD64703.1 - 0.00013 20.6 13.4 0.00013 20.6 9.3 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter MTHFR PF02219.12 EMD64705.1 - 7.5e-113 376.3 0.0 1e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TIM PF00121.13 EMD64706.1 - 3e-53 180.3 0.0 3.4e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase HBS1_N PF08938.5 EMD64706.1 - 0.026 14.6 0.0 7.2 6.8 0.0 2.2 2 0 0 2 2 2 0 HBS1 N-terminus Grp1_Fun34_YaaH PF01184.14 EMD64707.1 - 1.4e-30 106.2 18.9 1.8e-30 105.8 13.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.20 EMD64708.1 - 7e-19 68.3 0.0 8.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD64708.1 - 2.5e-12 47.0 0.2 3.1e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD64708.1 - 3.3e-08 33.3 0.1 4.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD64708.1 - 0.014 15.3 0.0 0.068 13.1 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_47 PF01532.15 EMD64709.1 - 1.2e-165 551.5 0.2 1.7e-165 551.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EMD64709.1 - 0.11 10.7 0.1 0.92 7.6 0.0 2.2 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Tim17 PF02466.14 EMD64710.1 - 5.4e-29 100.8 2.6 6.5e-29 100.5 1.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 EMD64710.1 - 0.07 12.4 0.9 0.12 11.7 0.6 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Pribosyltran PF00156.22 EMD64711.1 - 4.2e-17 62.0 0.1 1e-16 60.7 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain LSM PF01423.17 EMD64711.1 - 0.025 14.1 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 LSM domain UPRTase PF14681.1 EMD64711.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase eIF3g PF12353.3 EMD64712.1 - 2.4e-46 156.8 6.5 3.4e-46 156.2 4.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EMD64712.1 - 6.7e-19 67.3 0.0 1.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64712.1 - 2e-14 53.2 0.0 3.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD64712.1 - 2.8e-07 30.2 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3336 PF11815.3 EMD64713.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) Xpo1 PF08389.7 EMD64714.1 - 4.3e-30 104.5 0.9 1.2e-28 99.8 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EMD64714.1 - 1.4e-05 24.8 0.7 0.00012 21.9 0.2 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 EMD64714.1 - 0.15 12.5 4.6 0.77 10.3 0.0 4.5 6 0 0 6 6 6 0 HEAT-like repeat 5-FTHF_cyc-lig PF01812.15 EMD64715.1 - 1.6e-31 109.5 0.0 2.6e-28 99.0 0.0 2.0 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EMD64716.1 - 2.4e-83 278.6 1.0 2.9e-83 278.4 0.7 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Fungal_trans_2 PF11951.3 EMD64718.1 - 1.7e-20 73.0 1.0 3.8e-12 45.5 0.3 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64718.1 - 1.4e-07 31.3 11.5 2.3e-07 30.6 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC73 PF05179.9 EMD64721.1 - 6.1e-39 134.0 0.0 8.7e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Gly-zipper_OmpA PF13436.1 EMD64721.1 - 0.69 9.5 6.2 1.3 8.7 4.3 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Aconitase PF00330.15 EMD64722.1 - 1.5e-182 607.2 0.1 1.8e-182 606.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMD64722.1 - 8.4e-46 155.3 0.0 1.6e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.16 EMD64723.1 - 2.8e-32 111.7 13.2 2.8e-32 111.7 9.2 2.1 3 1 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.27 EMD64724.1 - 3.8e-26 89.9 2.6 1.7e-06 27.6 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 EMD64724.1 - 0.0046 15.1 0.7 0.49 8.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EMD64724.1 - 0.01 15.5 1.6 4.9 6.8 0.0 3.4 4 1 1 5 5 5 2 Transcription factor IIIC subunit delta N-term F-box-like PF12937.2 EMD64725.1 - 0.00023 20.8 0.9 0.00046 19.8 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD64725.1 - 0.0068 16.0 0.6 0.0068 16.0 0.4 1.8 2 0 0 2 2 2 1 F-box domain ECM11 PF15463.1 EMD64726.1 - 3.9e-38 130.8 9.0 3.9e-38 130.8 6.2 2.3 2 1 0 2 2 2 1 Extracellular mutant protein 11 Choline_transpo PF04515.7 EMD64729.1 - 1.4e-105 352.7 19.9 1.4e-105 352.7 13.8 2.3 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF4191 PF13829.1 EMD64729.1 - 0.87 8.6 5.4 4.2 6.4 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Mannitol_dh_C PF08125.8 EMD64730.1 - 1.1e-49 168.8 0.4 1.5e-49 168.3 0.3 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EMD64730.1 - 1.7e-18 67.0 0.9 1.7e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EMD64730.1 - 0.00089 18.9 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMD64730.1 - 0.0085 15.4 0.9 0.051 12.9 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PAP2_3 PF14378.1 EMD64731.1 - 5.4e-21 74.9 14.6 5.9e-19 68.3 2.6 2.8 3 0 0 3 3 3 2 PAP2 superfamily Cyclin PF08613.6 EMD64734.1 - 6.3e-24 85.0 0.0 8.6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin KRE9 PF05390.6 EMD64735.1 - 2.3e-13 50.4 6.1 2.3e-13 50.4 4.2 2.0 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EMD64735.1 - 3.5e-11 43.4 0.1 3.5e-11 43.4 0.1 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M24 PF00557.19 EMD64736.1 - 2.2e-54 184.1 0.3 2.9e-54 183.7 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMD64736.1 - 1.7e-28 98.6 0.0 4.5e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NMT_C PF02799.10 EMD64736.1 - 0.041 13.2 1.1 0.083 12.2 0.8 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Pro-kuma_activ PF09286.6 EMD64736.1 - 0.11 12.5 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain Glyco_hydro_26 PF02156.10 EMD64737.1 - 2e-90 303.4 5.1 2.7e-90 303.0 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Phage_lysis PF03245.8 EMD64737.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein NUDIX PF00293.23 EMD64738.1 - 4.1e-20 71.8 0.1 5.1e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain BRO1 PF03097.13 EMD64739.1 - 3e-137 457.3 4.1 3e-137 457.3 2.8 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMD64739.1 - 1.3e-96 323.1 12.8 2.4e-96 322.1 8.9 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.7 EMD64739.1 - 0.0098 15.0 0.9 0.14 11.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF416) CTDII PF01556.13 EMD64740.1 - 1.5e-26 92.0 5.4 1e-21 76.5 0.4 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EMD64740.1 - 1.1e-22 79.4 2.7 1.9e-22 78.7 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMD64740.1 - 1.1e-09 38.1 20.4 2.4e-09 37.1 14.1 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMD64740.1 - 1.6 8.4 7.3 8.2 6.1 0.4 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EMD64740.1 - 5.9 6.9 9.7 0.41 10.6 1.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain SAP30_Sin3_bdg PF13867.1 EMD64741.1 - 3.2e-06 26.9 0.0 2.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 VEK-30 PF12107.3 EMD64742.1 - 4.6 7.0 6.2 1.3 8.8 1.0 2.3 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway Glyco_hydro_61 PF03443.9 EMD64743.1 - 1.2e-53 182.1 0.0 1.5e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAM165 PF14981.1 EMD64744.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.4 1 1 0 1 1 1 0 FAM165 family Glyco_hydro_47 PF01532.15 EMD64745.1 - 1.9e-123 412.4 0.0 2.3e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zn_clus PF00172.13 EMD64746.1 - 4.5e-06 26.4 11.6 7.4e-06 25.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-FPG_IleRS PF06827.9 EMD64746.1 - 0.6 9.8 8.2 1.3 8.7 5.6 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Isochorismatase PF00857.15 EMD64747.1 - 2.7e-31 108.8 0.0 3.4e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_1 PF00583.19 EMD64748.1 - 4.6e-06 26.5 0.0 7.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD64748.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD64748.1 - 0.0035 17.4 0.0 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD64748.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein DUF3328 PF11807.3 EMD64749.1 - 1.1e-32 113.5 0.5 1.5e-32 113.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3060 PF11259.3 EMD64750.1 - 0.078 12.6 0.4 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Methyltransf_30 PF05430.6 EMD64751.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase GYD PF08734.6 EMD64751.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 GYD domain AA_permease_2 PF13520.1 EMD64752.1 - 4.6e-48 163.7 34.3 6.1e-48 163.4 23.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD64752.1 - 2.5e-34 118.4 29.6 2.5e-34 118.4 20.5 1.7 2 0 0 2 2 2 1 Amino acid permease PAT1 PF09770.4 EMD64753.1 - 0.36 9.0 3.2 0.4 8.8 2.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YqeY PF09424.5 EMD64754.1 - 3.1e-25 88.6 2.0 3.7e-25 88.4 1.4 1.1 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.13 EMD64754.1 - 0.0054 16.4 2.3 0.94 9.1 0.3 2.2 1 1 1 2 2 2 2 GatB domain ATP_bind_2 PF03668.10 EMD64754.1 - 0.033 13.2 0.1 0.04 12.9 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family Nucleoporin_C PF03177.9 EMD64755.1 - 1.2e-132 443.4 10.4 1.5e-132 443.1 7.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMD64755.1 - 1.7e-73 247.8 0.1 2.2e-73 247.4 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Arv1 PF04161.8 EMD64756.1 - 2.9e-42 144.9 0.0 4.7e-42 144.2 0.0 1.3 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.8 EMD64757.1 - 0.0018 18.2 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit H DUF2781 PF10914.3 EMD64759.1 - 8.4e-34 116.5 7.8 9.6e-34 116.3 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Sugar_tr PF00083.19 EMD64760.1 - 6.7e-114 380.9 29.0 1e-113 380.2 20.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD64760.1 - 5.2e-21 74.7 35.4 1.4e-16 60.1 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NB-ARC PF00931.17 EMD64761.1 - 1e-05 24.5 0.2 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.7 EMD64761.1 - 0.062 12.9 0.0 2.6 7.6 0.0 2.6 2 1 0 2 2 2 0 NACHT domain cobW PF02492.14 EMD64762.1 - 5e-43 146.6 0.1 7.3e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMD64762.1 - 6e-06 25.8 0.0 1.6e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EMD64762.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EMD64762.1 - 0.013 15.7 0.3 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain DCX PF03607.12 EMD64762.1 - 0.023 14.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Doublecortin AAA_22 PF13401.1 EMD64762.1 - 0.032 14.3 0.1 0.088 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMD64762.1 - 0.035 14.0 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EMD64762.1 - 0.039 13.6 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EMD64762.1 - 0.05 12.3 0.5 0.95 8.1 0.1 2.6 2 1 0 2 2 2 0 ArgK protein MMR_HSR1 PF01926.18 EMD64762.1 - 0.051 13.5 0.2 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 EMD64762.1 - 0.059 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EMD64762.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EMD64762.1 - 0.074 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EMD64762.1 - 0.083 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EMD64762.1 - 0.093 13.2 0.1 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EMD64762.1 - 0.1 12.3 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EMD64762.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EMD64762.1 - 0.11 12.8 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EMD64762.1 - 0.12 11.6 0.2 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Mob1_phocein PF03637.12 EMD64763.1 - 8.4e-26 90.6 0.4 1.3e-25 90.1 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans PF04082.13 EMD64764.1 - 3.3e-68 229.3 0.5 4.8e-68 228.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EMD64764.1 - 0.00011 22.2 16.2 0.00021 21.4 1.5 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD64764.1 - 0.00015 21.8 16.0 0.0004 20.5 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD64764.1 - 0.014 15.7 11.1 0.27 11.6 3.3 2.8 2 0 0 2 2 2 0 Zinc-finger double domain PAP1 PF08601.5 EMD64764.1 - 0.66 9.5 13.3 1.6 8.3 9.2 1.6 1 0 0 1 1 1 0 Transcription factor PAP1 DEAD PF00270.24 EMD64765.1 - 1.8e-25 89.3 0.0 3.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EMD64765.1 - 7.6e-12 45.6 2.7 9.4e-11 42.1 1.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) EF-hand_7 PF13499.1 EMD64765.1 - 1.6e-11 44.1 2.0 4.5e-07 29.9 0.3 2.9 2 1 1 3 3 3 2 EF-hand domain pair Helicase_C PF00271.26 EMD64765.1 - 4.3e-11 42.5 0.1 1.8e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain EF-hand_6 PF13405.1 EMD64765.1 - 3.9e-07 29.4 4.2 0.011 15.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EMD64765.1 - 1.4e-06 27.1 0.2 0.057 12.7 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EMD64765.1 - 0.00011 22.0 0.0 0.44 10.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain CDT1 PF08839.6 EMD64765.1 - 0.0027 17.6 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like EF-hand_5 PF13202.1 EMD64765.1 - 0.13 11.6 2.2 3.5 7.1 0.3 2.9 2 0 0 2 2 2 0 EF hand HIT PF01230.18 EMD64767.1 - 3.2e-24 85.3 0.6 4.7e-24 84.7 0.4 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMD64767.1 - 2.4e-06 27.7 0.4 4e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding R3H-assoc PF13902.1 EMD64769.1 - 7.4e-28 97.1 3.4 1.1e-27 96.5 2.3 1.3 1 0 0 1 1 1 1 R3H-associated N-terminal domain Peptidase_M28 PF04389.12 EMD64770.1 - 3.5e-28 98.5 0.0 6.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD64770.1 - 9.4e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 adh_short PF00106.20 EMD64771.1 - 1.1e-21 77.4 0.0 1.8e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD64771.1 - 5.5e-12 45.7 0.0 8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD64771.1 - 1.4e-10 41.3 0.2 8.3e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD64771.1 - 2e-05 24.1 0.0 4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD64771.1 - 0.0002 20.3 0.1 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMD64771.1 - 0.0002 21.4 0.1 0.0011 18.9 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD64771.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ATP-grasp_5 PF13549.1 EMD64771.1 - 0.037 13.2 0.4 0.11 11.6 0.1 1.9 2 1 0 2 2 2 0 ATP-grasp domain NmrA PF05368.8 EMD64771.1 - 0.085 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EMD64771.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3053 PF11254.3 EMD64771.1 - 0.14 11.3 0.2 0.58 9.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DUF1664 PF07889.7 EMD64771.1 - 0.15 11.8 0.3 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CoA_binding_2 PF13380.1 EMD64773.1 - 2e-25 89.2 0.0 2.5e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Aminotran_3 PF00202.16 EMD64774.1 - 2.1e-98 329.3 0.5 2.5e-98 329.0 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMD64774.1 - 0.024 13.6 0.0 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Col_cuticle_N PF01484.12 EMD64775.1 - 0.37 10.5 0.1 0.37 10.5 0.0 3.1 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain adh_short PF00106.20 EMD64776.1 - 2.2e-16 60.1 3.1 4.3e-16 59.2 0.8 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD64776.1 - 1.6e-12 47.7 0.0 3.5e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD64776.1 - 2.2e-05 24.2 0.9 0.00052 19.7 0.3 2.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EMD64776.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD64776.1 - 0.0018 18.3 0.1 0.0037 17.2 0.0 1.7 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMD64776.1 - 0.032 14.0 3.0 0.068 12.9 0.5 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lectin_N PF03954.9 EMD64780.1 - 0.45 9.9 6.4 5.8 6.3 0.8 3.3 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Thymidylat_synt PF00303.14 EMD64781.1 - 3.4e-110 367.3 0.0 3.8e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase PAN_1 PF00024.21 EMD64782.1 - 5.2e-10 38.9 8.4 0.0045 16.7 0.8 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 EMD64782.1 - 1.9e-09 37.0 19.3 7.5e-05 22.3 1.0 3.7 3 0 0 3 3 3 3 PAN domain Herpes_gE PF02480.11 EMD64782.1 - 0.0023 16.2 0.0 0.0037 15.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EMD64782.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EMD64782.1 - 0.05 12.9 0.3 0.088 12.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SCF PF02404.10 EMD64782.1 - 0.26 10.4 4.3 0.1 11.8 1.1 1.5 2 0 0 2 2 2 0 Stem cell factor MANEC PF07502.9 EMD64782.1 - 1.4 9.0 9.0 0.083 12.8 0.6 2.9 3 0 0 3 3 3 0 MANEC domain NOGCT PF08155.6 EMD64783.1 - 1.4e-28 98.3 2.5 3e-28 97.2 1.7 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EMD64783.1 - 1.1e-24 86.0 0.6 2.5e-24 84.9 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EMD64783.1 - 3.3e-14 52.8 0.0 7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD64783.1 - 9.7e-07 28.1 0.0 2.5e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMD64783.1 - 0.0023 18.4 0.3 0.0093 16.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EMD64783.1 - 0.011 15.9 2.2 0.15 12.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain PLRV_ORF5 PF01690.12 EMD64783.1 - 3.9 6.5 8.2 5.7 5.9 5.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1989 PF09347.5 EMD64784.1 - 4.1e-27 94.6 0.4 1.8e-17 63.3 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) ArfGap PF01412.13 EMD64785.1 - 4.2e-35 120.0 1.1 7.8e-35 119.1 0.8 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-RanBP PF00641.13 EMD64786.1 - 0.015 14.4 0.8 0.015 14.4 0.5 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 EMD64786.1 - 0.059 13.2 3.8 0.19 11.6 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon PAN_4 PF14295.1 EMD64787.1 - 0.38 10.4 2.9 2 8.1 2.0 2.0 1 1 0 1 1 1 0 PAN domain Glyco_hydro_3 PF00933.16 EMD64788.1 - 2e-83 279.8 0.0 2.9e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD64788.1 - 7.2e-50 169.6 0.0 1.2e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD64788.1 - 1.2e-25 89.2 0.1 2.2e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC2_membrane PF01061.19 EMD64789.1 - 8.8e-87 289.6 65.4 2.9e-47 160.5 17.0 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EMD64789.1 - 2e-37 126.9 1.9 3.5e-33 113.3 0.0 3.7 5 0 0 5 5 3 2 CDR ABC transporter ABC_tran PF00005.22 EMD64789.1 - 4.1e-37 127.5 0.0 7.6e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EMD64789.1 - 1.1e-18 67.0 0.0 2.7e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EMD64789.1 - 5.8e-09 36.2 1.2 1.8e-05 24.8 0.0 3.0 4 0 0 4 4 2 2 AAA ATPase domain AAA_25 PF13481.1 EMD64789.1 - 1.8e-08 34.0 0.0 0.00018 21.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMD64789.1 - 5.1e-07 29.1 0.5 0.00052 19.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMD64789.1 - 9.6e-06 24.8 0.0 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMD64789.1 - 3.5e-05 24.1 0.2 0.039 14.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EMD64789.1 - 3.8e-05 24.4 0.0 0.047 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD64789.1 - 3.8e-05 23.5 0.0 0.0033 17.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EMD64789.1 - 5.9e-05 22.5 0.7 0.001 18.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 EMD64789.1 - 8.8e-05 21.6 22.4 8.8e-05 21.6 15.5 4.2 2 2 1 3 3 3 1 ABC-2 family transporter protein MMR_HSR1 PF01926.18 EMD64789.1 - 0.00073 19.4 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMD64789.1 - 0.00085 19.4 0.2 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMD64789.1 - 0.0025 17.0 0.0 2.6 7.2 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD64789.1 - 0.0047 16.9 0.0 0.31 10.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EMD64789.1 - 0.0063 16.4 0.3 0.2 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD64789.1 - 0.0093 15.6 0.9 1 9.0 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 EMD64789.1 - 0.017 15.4 0.0 0.26 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD64789.1 - 0.028 14.1 0.7 11 5.9 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 EMD64789.1 - 0.032 14.7 0.0 5.4 7.5 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 EMD64789.1 - 0.05 12.3 0.2 3.8 6.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA PF00004.24 EMD64789.1 - 0.058 13.5 0.0 3.5 7.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2681 PF10883.3 EMD64789.1 - 0.08 13.1 3.9 3.3 7.9 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) UPF0079 PF02367.12 EMD64789.1 - 0.096 12.3 1.1 0.41 10.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EMD64789.1 - 0.15 11.5 0.6 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EMD64789.1 - 0.43 9.5 0.0 1 8.3 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain KAR9 PF08580.5 EMD64789.1 - 0.71 8.0 6.0 1.1 7.4 4.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TIP41 PF04176.8 EMD64790.1 - 2.7e-79 264.6 0.7 3.3e-79 264.3 0.5 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EMD64791.1 - 1.3e-70 237.4 0.0 1.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64791.1 - 5.3e-43 146.9 0.0 7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD64791.1 - 1.2e-08 34.2 0.0 1.2e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMD64791.1 - 8.2e-05 21.7 0.1 0.00015 20.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMD64791.1 - 0.023 14.0 0.2 0.068 12.5 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EMD64791.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EMD64792.1 - 5.4e-66 221.3 2.1 6.4e-66 221.0 1.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EMD64792.1 - 0.025 14.2 2.6 0.041 13.5 1.8 1.6 1 1 0 1 1 1 0 SprT-like family AA_kinase PF00696.23 EMD64793.1 - 7.6e-39 133.6 0.9 1.2e-38 133.0 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EMD64793.1 - 2.1e-15 56.2 1.5 1.9e-08 33.9 0.1 3.1 3 0 0 3 3 3 2 PUA domain Glyco_hydro_28 PF00295.12 EMD64794.1 - 2.1e-79 266.8 12.0 2.6e-79 266.5 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4595 PF15283.1 EMD64794.1 - 0.037 13.6 0.4 0.061 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Mito_fiss_reg PF05308.6 EMD64794.1 - 0.41 9.9 1.1 0.58 9.4 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PHO4 PF01384.15 EMD64796.1 - 9.3e-109 363.0 9.8 1.1e-108 362.7 6.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 EMD64796.1 - 0.019 14.7 0.1 0.056 13.2 0.0 1.8 1 0 0 1 1 1 0 Glycophorin A EamA PF00892.15 EMD64798.1 - 1.9e-25 89.3 30.4 4.1e-14 52.6 7.3 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMD64798.1 - 7.3e-10 39.0 22.3 1.6e-05 25.0 5.9 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 EMD64798.1 - 9.8e-06 24.6 5.8 0.00016 20.7 0.1 2.8 3 0 0 3 3 3 2 UAA transporter family TPT PF03151.11 EMD64798.1 - 0.0072 15.9 13.9 0.0075 15.9 3.9 3.2 3 0 0 3 3 3 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EMD64798.1 - 0.95 8.5 7.9 0.37 9.8 0.3 2.9 1 1 2 3 3 3 0 Nucleotide-sugar transporter Pectinesterase PF01095.14 EMD64799.1 - 3.3e-51 173.6 7.8 4.3e-51 173.2 5.4 1.0 1 0 0 1 1 1 1 Pectinesterase CHORD PF04968.7 EMD64800.1 - 0.00022 21.3 3.2 0.00039 20.5 2.2 1.3 1 0 0 1 1 1 1 CHORD Cytochrom_C_2 PF01322.15 EMD64800.1 - 0.011 16.2 0.1 0.033 14.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C' Cut8_M PF14483.1 EMD64800.1 - 0.18 11.6 1.2 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Cut8 dimerisation domain Pec_lyase_C PF00544.14 EMD64801.1 - 0.002 17.6 2.8 0.003 17.0 1.9 1.3 1 0 0 1 1 1 1 Pectate lyase IncA PF04156.9 EMD64802.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein VPEP PF07589.6 EMD64802.1 - 1.4 8.9 5.0 1.8 8.5 2.5 2.0 1 1 0 1 1 1 0 PEP-CTERM motif Gram_pos_anchor PF00746.16 EMD64802.1 - 1.5 8.7 5.9 3.8 7.4 4.1 1.7 1 0 0 1 1 1 0 Gram positive anchor Glyco_transf_90 PF05686.7 EMD64803.1 - 3.9e-18 65.3 0.1 3.5e-14 52.3 0.2 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 MFS_1 PF07690.11 EMD64804.1 - 8e-38 130.0 21.8 2.1e-37 128.6 15.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily EXS PF03124.9 EMD64804.1 - 2.5 7.0 8.6 0.93 8.4 3.4 2.1 2 1 0 2 2 2 0 EXS family GMC_oxred_N PF00732.14 EMD64805.1 - 1.3e-63 214.8 0.0 2.3e-63 214.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD64805.1 - 3.6e-35 121.3 0.0 6.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMD64805.1 - 8.4e-05 21.6 0.8 0.00018 20.5 0.5 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMD64805.1 - 0.0046 15.8 1.0 0.014 14.3 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD64805.1 - 0.0062 15.4 2.0 1.2 7.9 1.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EMD64805.1 - 0.099 11.7 1.2 0.18 10.8 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Adaptin_binding PF10199.4 EMD64806.1 - 2.7e-05 24.4 1.2 0.00091 19.5 0.4 2.1 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 RRN3 PF05327.6 EMD64806.1 - 0.0021 16.2 1.8 0.0026 15.9 1.2 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 EMD64806.1 - 0.0082 15.5 6.5 0.016 14.6 4.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Tim54 PF11711.3 EMD64806.1 - 0.036 12.6 0.3 0.052 12.1 0.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRANC PF09372.5 EMD64806.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PRANC domain TFIIA PF03153.8 EMD64806.1 - 0.19 11.6 13.9 0.27 11.0 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EMD64806.1 - 0.26 9.1 18.0 0.37 8.6 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMD64806.1 - 0.48 8.3 11.6 0.71 7.8 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EMD64806.1 - 1.1 8.9 7.5 2.6 7.7 5.2 1.6 1 0 0 1 1 1 0 FAM176 family VID27 PF08553.5 EMD64806.1 - 1.4 7.0 12.2 2.1 6.4 8.4 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Herpes_LMP1 PF05297.6 EMD64806.1 - 1.4 7.7 8.4 1.9 7.3 5.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Astro_capsid PF03115.9 EMD64806.1 - 2 6.5 6.3 3 5.9 4.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sporozoite_P67 PF05642.6 EMD64806.1 - 2.4 5.9 8.0 3.9 5.2 5.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytomega_UL84 PF06284.6 EMD64806.1 - 4.8 5.4 6.0 7.4 4.8 4.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Daxx PF03344.10 EMD64806.1 - 5 5.4 21.8 8.1 4.7 15.1 1.3 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EMD64806.1 - 7.1 5.5 14.2 11 4.8 9.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ARF7EP_C PF14949.1 EMD64807.1 - 7 7.1 21.3 0.16 12.4 3.9 2.4 2 0 0 2 2 2 0 ARF7 effector protein C-terminus ZZ PF00569.12 EMD64811.1 - 5.2e-12 45.0 4.4 1e-11 44.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EMD64811.1 - 2.4e-10 40.3 0.0 8.7e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EMD64811.1 - 7.9e-06 25.8 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 EMD64812.1 - 4.7e-70 235.7 0.0 6.2e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD64812.1 - 2.6e-34 118.4 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMD64812.1 - 6.8e-10 39.3 0.3 1.8e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMD64812.1 - 0.00017 20.6 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PGI PF00342.14 EMD64813.1 - 3.5e-221 734.7 2.2 4e-221 734.5 1.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.13 EMD64813.1 - 0.022 14.2 0.2 0.075 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF115 Ribosomal_S21 PF01165.15 EMD64815.1 - 2.9e-09 36.2 1.6 4.3e-09 35.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 EMD64816.1 - 6.5e-12 45.3 0.3 1.6e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EMD64816.1 - 0.0034 16.9 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2795 PF11387.3 EMD64816.1 - 0.031 14.1 0.1 0.089 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) RRM_6 PF14259.1 EMD64816.1 - 0.17 11.9 0.4 2.9 7.9 0.0 3.2 5 0 0 5 5 5 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MR_MLE_C PF13378.1 EMD64817.1 - 3.9e-18 65.4 0.0 2.3e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMD64817.1 - 5.3e-12 46.0 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EMD64817.1 - 0.00032 19.7 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.11 EMD64817.1 - 0.00051 20.0 0.0 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ras PF00071.17 EMD64818.1 - 5e-09 35.7 0.0 7.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ras family CFEM PF05730.6 EMD64819.1 - 3.8e-08 33.0 5.2 4.8e-08 32.7 3.6 1.2 1 0 0 1 1 1 1 CFEM domain zf-H2C2_2 PF13465.1 EMD64821.1 - 5.5e-10 39.0 16.7 8.5e-06 25.8 2.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMD64821.1 - 4.2e-08 33.0 13.5 0.0012 19.0 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD64821.1 - 1.2e-05 25.2 12.6 0.02 15.1 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD64821.1 - 0.58 10.3 3.2 0.27 11.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Staphylcoagulse PF04022.7 EMD64823.1 - 0.14 11.5 0.7 0.31 10.4 0.5 1.6 1 0 0 1 1 1 0 Staphylocoagulase repeat RecA PF00154.16 EMD64824.1 - 2.7e-08 33.2 0.4 7.9e-08 31.7 0.3 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EMD64824.1 - 3.5e-08 32.8 0.1 8.2e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 EMD64824.1 - 5.6e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.6 EMD64824.1 - 0.00025 20.0 0.0 0.0011 17.8 0.0 1.9 1 1 0 1 1 1 1 Rad51 IstB_IS21 PF01695.12 EMD64824.1 - 0.00047 19.6 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EMD64824.1 - 0.0018 17.7 0.0 0.0062 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EMD64824.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EMD64824.1 - 0.031 13.4 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EMD64824.1 - 0.055 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EMD64824.1 - 0.1 13.4 0.1 0.28 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMD64824.1 - 0.15 12.1 0.1 0.5 10.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMD64824.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter MOSC PF03473.12 EMD64825.1 - 3.8e-17 62.0 0.0 6.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EMD64825.1 - 4.1e-11 42.6 0.0 7.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Abhydrolase_6 PF12697.2 EMD64826.1 - 1.2e-14 54.7 0.1 1.4e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD64826.1 - 9.2e-11 41.6 0.0 1.6e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMD64826.1 - 0.0018 17.5 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMD64826.1 - 0.003 17.1 0.0 0.013 15.0 0.0 2.0 2 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 EMD64826.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 EMD64826.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAN_4 PF14295.1 EMD64827.1 - 0.039 13.6 4.3 2.1 8.1 0.6 2.8 2 0 0 2 2 2 0 PAN domain WD40 PF00400.27 EMD64828.1 - 1.2e-16 59.8 18.8 9.4e-07 28.4 0.3 5.6 4 1 1 5 5 5 4 WD domain, G-beta repeat Nbas_N PF15492.1 EMD64828.1 - 0.052 12.6 0.3 5.4 6.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF678 PF05077.7 EMD64828.1 - 0.17 11.9 0.3 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF678) PAS_3 PF08447.6 EMD64829.1 - 2.7e-11 43.4 0.0 1.3e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EMD64829.1 - 8.8e-08 32.4 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EMD64829.1 - 1e-06 28.6 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMD64829.1 - 0.00021 21.0 0.0 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EMD64829.1 - 0.0015 18.5 0.0 0.76 9.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold DUF448 PF04296.8 EMD64829.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Zip PF02535.17 EMD64830.1 - 0.15 11.0 1.5 0.25 10.3 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SET PF00856.23 EMD64831.1 - 2e-07 31.4 2.5 2.6e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 SET domain PHD PF00628.24 EMD64831.1 - 4.3e-05 23.1 9.7 8e-05 22.2 6.7 1.5 1 0 0 1 1 1 1 PHD-finger COesterase PF00135.23 EMD64832.1 - 4.5e-18 65.2 0.0 8.5e-15 54.4 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family Lectin_C PF00059.16 EMD64832.1 - 0.021 15.4 0.7 0.8 10.3 0.0 2.4 1 1 1 2 2 2 0 Lectin C-type domain Ran_BP1 PF00638.13 EMD64834.1 - 3.4e-15 56.1 0.1 6.5e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain Yip1 PF04893.12 EMD64835.1 - 3.9e-13 49.2 12.2 5.8e-13 48.7 8.5 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EMD64835.1 - 2.9 7.5 12.4 5.6 6.5 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) GalP_UDP_transf PF01087.17 EMD64836.1 - 1.9e-69 233.3 0.1 1.9e-67 226.9 0.0 2.3 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EMD64836.1 - 4.5e-56 188.9 0.0 9.6e-56 187.8 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EMD64836.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 HIT domain Tyr-DNA_phospho PF06087.7 EMD64837.1 - 6.7e-132 440.2 0.0 7.9e-132 440.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EMD64837.1 - 0.00019 21.1 0.0 0.05 13.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain DUF4654 PF15547.1 EMD64837.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) HlyC PF02794.11 EMD64837.1 - 0.066 12.8 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 RTX toxin acyltransferase family FA_desaturase PF00487.19 EMD64838.1 - 1.1e-18 67.5 12.3 2e-18 66.7 8.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMD64838.1 - 1.6e-16 59.8 0.0 3.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.15 EMD64839.1 - 2.9e-66 223.5 33.0 5.7e-65 219.3 22.8 2.0 1 1 0 1 1 1 1 Permease family Methyltransf_16 PF10294.4 EMD64840.1 - 1.4e-15 57.1 0.0 6.6e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase AMP-binding PF00501.23 EMD64841.1 - 8.5e-85 284.6 0.0 1.3e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD64841.1 - 0.00056 20.7 0.4 0.0019 19.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EMD64842.1 - 5.1e-21 75.3 0.0 8.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD64842.1 - 8.3e-14 51.9 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD64842.1 - 0.00013 21.7 0.0 0.00038 20.1 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD64842.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD64842.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMD64842.1 - 0.093 12.5 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMD64842.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_S17 PF00366.15 EMD64843.1 - 1.2e-28 98.9 0.3 1.6e-28 98.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Erg28 PF03694.8 EMD64844.1 - 1.5e-42 144.0 0.4 2e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein LCCL PF03815.14 EMD64845.1 - 1.3e-20 73.1 0.4 4.3e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 LCCL domain PAN_1 PF00024.21 EMD64845.1 - 3.1e-09 36.4 4.3 4.9e-05 23.0 0.4 2.4 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 EMD64845.1 - 2.7e-07 30.2 14.9 5.3e-07 29.2 0.5 3.0 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.6 EMD64845.1 - 0.019 14.7 5.3 0.32 10.8 0.3 2.7 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.7 EMD64845.1 - 0.056 13.0 4.5 2.8 7.6 0.3 2.6 2 0 0 2 2 2 0 PAN-like domain p450 PF00067.17 EMD64846.1 - 5.6e-52 176.7 0.0 1.1e-51 175.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Trehalase PF01204.13 EMD64847.1 - 6.7e-115 384.6 8.4 2e-114 383.0 5.8 1.7 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EMD64847.1 - 1.8e-06 26.9 3.3 2e-05 23.4 2.3 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase TPR_12 PF13424.1 EMD64847.1 - 0.037 13.9 2.9 0.041 13.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD64847.1 - 0.17 11.8 1.8 0.27 11.2 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Cutinase PF01083.17 EMD64848.1 - 5.6e-56 189.0 0.6 6.7e-56 188.8 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD64848.1 - 0.001 18.5 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EMD64848.1 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EMD64848.1 - 0.033 13.9 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DHO_dh PF01180.16 EMD64849.1 - 1.5e-65 221.0 0.2 9e-54 182.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EMD64849.1 - 0.0017 17.6 3.3 0.12 11.6 0.0 2.6 3 0 0 3 3 3 2 PcrB family NMO PF03060.10 EMD64849.1 - 0.012 14.8 0.3 0.023 13.8 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Glyco_hydro_28 PF00295.12 EMD64850.1 - 1e-47 162.7 12.2 1.3e-47 162.3 8.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AMP-binding PF00501.23 EMD64851.1 - 5.6e-24 84.3 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme U-box PF04564.10 EMD64852.1 - 3.7e-22 78.0 0.0 7.5e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EMD64852.1 - 3.8e-18 64.8 5.0 3.2e-16 58.7 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMD64852.1 - 1e-09 37.5 3.9 0.00026 20.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD64852.1 - 6.8e-08 31.8 0.8 0.0013 18.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD64852.1 - 3.4e-05 24.0 0.4 0.031 14.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD64852.1 - 0.00043 20.2 3.8 1.3 9.4 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD64852.1 - 0.00062 20.3 1.0 0.26 12.0 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64852.1 - 0.002 18.5 0.4 0.71 10.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2738 PF10927.3 EMD64852.1 - 0.0035 16.4 0.1 0.0045 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) TPR_12 PF13424.1 EMD64852.1 - 0.018 14.9 1.1 0.94 9.4 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD64852.1 - 0.025 14.6 0.7 0.058 13.5 0.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EMD64852.1 - 0.053 13.6 3.1 6.7 6.9 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD64852.1 - 0.068 13.0 0.1 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fe-ADH PF00465.14 EMD64854.1 - 1.7e-60 204.6 0.0 2.2e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMD64854.1 - 6e-12 45.4 0.0 8.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase HSP70 PF00012.15 EMD64855.1 - 1.6e-266 885.0 16.7 1.9e-266 884.8 11.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD64855.1 - 5.4e-13 48.2 7.0 2.1e-12 46.2 1.2 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 EMD64855.1 - 0.00017 21.2 0.2 0.00069 19.2 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMD64855.1 - 0.017 14.9 13.6 2 8.2 0.4 5.1 3 3 0 3 3 3 0 Cell division protein FtsA DUF4363 PF14276.1 EMD64855.1 - 0.099 12.3 4.2 0.22 11.2 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 EMD64855.1 - 2 7.4 10.8 3.6 6.6 0.2 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EMD64856.1 - 2e-17 62.5 0.0 4.7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EMD64856.1 - 0.0026 17.5 1.3 0.5 10.3 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EMD64856.1 - 0.048 13.9 1.4 59 4.1 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain DUF2217 PF10265.4 EMD64856.1 - 0.089 11.5 1.7 0.12 11.0 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cys_Met_Meta_PP PF01053.15 EMD64857.1 - 3.4e-138 460.1 0.0 4e-138 459.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD64857.1 - 1.1e-06 27.8 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMD64857.1 - 1.5e-05 24.2 0.0 3.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMD64857.1 - 8.8e-05 21.3 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EMD64857.1 - 0.0003 19.2 0.1 0.0016 16.8 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 EMD64857.1 - 0.00087 18.1 0.1 0.0026 16.5 0.1 1.6 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EMD64857.1 - 0.005 16.0 0.0 0.01 15.0 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase MAF_flag10 PF01973.13 EMD64857.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 CI-B14_5a PF07347.7 EMD64858.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Bestrophin PF01062.16 EMD64860.1 - 2e-47 161.5 2.7 2.9e-46 157.7 1.8 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SnoaL PF07366.7 EMD64861.1 - 8.6e-36 122.3 0.0 1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD64861.1 - 1.8e-20 73.2 0.0 2.1e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_8 PF05148.10 EMD64862.1 - 1.2e-49 168.9 0.1 6.2e-27 94.6 0.0 3.2 4 0 0 4 4 4 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EMD64862.1 - 1.1e-07 32.2 0.0 3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD64862.1 - 0.001 18.6 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EMD64862.1 - 0.053 13.9 0.3 0.52 10.8 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain Acetyltransf_1 PF00583.19 EMD64864.1 - 1.4e-09 37.8 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD64864.1 - 3.4e-07 30.3 0.0 5.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD64864.1 - 3.4e-06 27.1 0.0 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD64864.1 - 2.7e-05 23.8 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EMD64864.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMD64864.1 - 0.041 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD64864.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD64864.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_35 PF01301.14 EMD64865.1 - 3.4e-86 289.4 1.1 5.1e-86 288.9 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EMD64865.1 - 5.6e-48 161.8 6.7 4.3e-23 81.6 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EMD64865.1 - 3.3e-44 150.4 0.9 6.6e-44 149.4 0.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EMD64865.1 - 7.6e-26 89.3 0.1 3.4e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EMD64865.1 - 0.0005 19.3 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CUE PF02845.11 EMD64867.1 - 3e-10 39.3 0.0 4.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 CUE domain DPBB_1 PF03330.13 EMD64868.1 - 5.2e-10 39.1 0.5 8.7e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMD64868.1 - 0.0035 16.9 0.2 0.0057 16.3 0.2 1.3 1 0 0 1 1 1 1 Barwin family DUF1899 PF08953.6 EMD64868.1 - 0.18 11.4 3.1 6.3 6.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) SKG6 PF08693.5 EMD64871.1 - 0.0031 16.7 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EMD64871.1 - 0.015 13.5 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IBR PF01485.16 EMD64872.1 - 3.7e-06 26.7 31.3 5.1e-05 23.0 2.5 4.3 4 1 0 4 4 4 3 IBR domain T2SM PF04612.7 EMD64873.1 - 0.011 15.5 0.3 0.018 14.8 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2800 PF10926.3 EMD64873.1 - 0.023 13.8 0.1 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) BLOC1_2 PF10046.4 EMD64873.1 - 0.025 14.7 0.5 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.3 EMD64873.1 - 0.026 14.2 0.6 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EMD64873.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 IncA protein VIT1 PF01988.14 EMD64873.1 - 0.037 13.5 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 VIT family DUF3053 PF11254.3 EMD64873.1 - 0.077 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) GAS PF13851.1 EMD64873.1 - 0.088 11.9 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EMD64873.1 - 0.13 12.4 2.2 0.85 9.9 0.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2802 PF10975.3 EMD64873.1 - 1.2 8.9 4.4 0.59 9.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) FlxA PF14282.1 EMD64873.1 - 9.9 6.1 9.5 1.4 8.9 1.8 2.6 3 0 0 3 3 3 0 FlxA-like protein PigN PF04987.9 EMD64874.1 - 1.6e-162 541.2 27.9 1.6e-162 541.2 19.4 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EMD64874.1 - 9e-11 41.6 0.8 2.2e-09 37.1 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD64874.1 - 9.6e-08 31.5 0.1 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EMD64874.1 - 0.0028 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 EMD64874.1 - 0.053 12.2 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Alkaline phosphatase GDI PF00996.13 EMD64875.1 - 6.8e-186 617.8 0.0 9.3e-186 617.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EMD64875.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EMD64876.1 - 4.6e-19 68.1 1.2 8.2e-19 67.3 0.4 1.7 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) bZIP_1 PF00170.16 EMD64877.1 - 1.1e-08 34.9 9.2 1.6e-08 34.3 6.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD64877.1 - 7.6e-07 28.8 9.1 1.3e-06 28.1 6.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD64877.1 - 0.00038 20.7 6.0 0.00076 19.7 4.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor CAF-1_p150 PF11600.3 EMD64877.1 - 0.0021 17.4 11.6 0.0024 17.2 8.0 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3450 PF11932.3 EMD64877.1 - 0.0022 17.2 1.6 0.0022 17.2 1.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) CCDC155 PF14662.1 EMD64877.1 - 0.0056 16.2 2.2 0.0073 15.9 1.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF745 PF05335.8 EMD64877.1 - 0.0061 16.0 2.1 0.0061 16.0 1.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF745) FTA4 PF13093.1 EMD64877.1 - 0.0096 15.3 3.3 0.011 15.2 2.3 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IFT20 PF14931.1 EMD64877.1 - 0.012 15.4 2.1 0.013 15.4 1.5 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF904 PF06005.7 EMD64877.1 - 0.019 15.2 2.3 0.03 14.5 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EMD64877.1 - 0.02 14.3 2.0 0.02 14.3 1.4 1.7 2 0 0 2 2 2 0 Septum formation initiator Tmemb_cc2 PF10267.4 EMD64877.1 - 0.022 13.3 5.7 0.026 13.1 4.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Striatin PF08232.7 EMD64877.1 - 0.025 14.8 1.6 0.025 14.8 1.1 2.2 1 1 1 2 2 2 0 Striatin family TPD52 PF04201.10 EMD64877.1 - 0.037 13.7 1.7 0.037 13.7 1.2 1.7 1 1 0 1 1 1 0 Tumour protein D52 family DUF4140 PF13600.1 EMD64877.1 - 0.043 14.2 3.8 0.059 13.8 2.6 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 EMD64877.1 - 0.058 11.6 11.6 0.061 11.6 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein WD40_alt PF14077.1 EMD64877.1 - 0.06 12.9 1.7 0.13 11.9 1.1 1.6 1 1 0 1 1 1 0 Alternative WD40 repeat motif DUF724 PF05266.9 EMD64877.1 - 0.061 12.9 2.7 0.07 12.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sipho_Gp157 PF05565.6 EMD64877.1 - 0.099 12.2 2.1 0.16 11.5 1.5 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 HALZ PF02183.13 EMD64877.1 - 0.14 11.8 1.6 0.52 10.0 1.2 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EMD64877.1 - 0.2 12.0 2.9 0.15 12.4 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ELL PF10390.4 EMD64877.1 - 0.21 10.7 5.7 0.23 10.6 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF1423 PF07227.6 EMD64877.1 - 0.37 9.3 7.0 0.39 9.3 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) FAM163 PF15069.1 EMD64877.1 - 0.39 11.2 1.7 0.42 11.1 1.1 1.1 1 0 0 1 1 1 0 FAM163 family KLRAQ PF10205.4 EMD64877.1 - 0.82 9.7 6.7 0.15 12.0 1.3 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Herpes_DNAp_acc PF04929.7 EMD64877.1 - 1.1 8.1 7.9 1.3 7.8 5.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 EMD64877.1 - 5 6.8 9.0 6.5 6.4 6.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF2146 PF10220.4 EMD64877.1 - 10 3.9 8.3 11 3.8 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Peptidase_M3 PF01432.15 EMD64879.1 - 3.2e-160 534.1 0.1 4.2e-160 533.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Condensation PF00668.15 EMD64880.1 - 1.3e-74 250.7 0.0 3.1e-34 118.2 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 EMD64880.1 - 3.6e-49 167.2 0.0 5.8e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EMD64880.1 - 6.1e-08 32.8 0.0 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD64880.1 - 1.6e-07 32.1 0.1 5.2e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 EMD64881.1 - 4.9e-08 32.1 0.0 8e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Methyltransf_PK PF05891.7 EMD64881.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Condensation PF00668.15 EMD64882.1 - 4.5e-10 38.8 0.0 2.5e-09 36.4 0.0 1.8 1 1 1 2 2 2 1 Condensation domain AMP-binding PF00501.23 EMD64883.1 - 2e-88 296.6 0.0 2.9e-88 296.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD64883.1 - 1.4e-18 67.6 0.4 3.7e-17 63.0 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_C14 PF00656.17 EMD64884.1 - 4.3e-23 82.2 0.0 6.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain PRA1 PF03208.14 EMD64886.1 - 5.3 6.3 10.7 5.1 6.4 7.4 1.0 1 0 0 1 1 1 0 PRA1 family protein CHAT PF12770.2 EMD64887.1 - 5e-33 114.4 0.3 9.6e-33 113.5 0.1 1.6 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EMD64887.1 - 2.8e-05 23.9 41.7 1.7 8.5 1.1 11.9 4 2 6 12 12 12 6 Tetratricopeptide repeat MMR_HSR1_C PF08438.5 EMD64887.1 - 9.7e-05 22.5 0.0 46 4.2 0.0 7.2 4 1 6 10 10 10 0 GTPase of unknown function C-terminal DUF4600 PF15372.1 EMD64887.1 - 0.073 13.2 0.6 0.21 11.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) TPR_9 PF13371.1 EMD64887.1 - 0.29 11.0 10.8 0.46 10.3 0.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD64887.1 - 1.2 9.1 68.3 0.37 10.7 0.0 12.9 14 0 0 14 14 14 0 Tetratricopeptide repeat CCDC144C PF14915.1 EMD64887.1 - 7.4 5.3 6.9 38 3.0 0.0 4.0 4 1 0 4 4 4 0 CCDC144C protein coiled-coil region RGS-like PF09128.6 EMD64888.1 - 0.054 12.9 0.3 0.064 12.7 0.2 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DivIC PF04977.10 EMD64891.1 - 0.006 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.13 EMD64891.1 - 0.043 13.5 0.3 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 EMD64891.1 - 0.088 13.1 0.1 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) GOLGA2L5 PF15070.1 EMD64891.1 - 0.17 10.3 4.0 0.049 12.1 0.8 1.4 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Myc_N PF01056.13 EMD64891.1 - 6.9 5.7 10.1 14 4.7 7.1 1.4 1 1 0 1 1 1 0 Myc amino-terminal region DDE_3 PF13358.1 EMD64893.1 - 0.0045 16.7 0.1 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EMD64894.1 - 3e-05 23.5 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EMD64894.1 - 7e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EMD64894.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 EMD64894.1 - 0.011 16.5 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EMD64894.1 - 0.022 13.9 0.2 0.094 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EMD64894.1 - 0.059 12.8 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hydro_31 PF01055.21 EMD64895.1 - 1.2e-170 568.1 1.2 1.6e-170 567.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD64895.1 - 6.6e-09 35.5 0.6 2.3e-08 33.7 0.4 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Prp19 PF08606.6 EMD64896.1 - 3.2e-33 113.2 1.1 5.5e-33 112.5 0.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EMD64896.1 - 2.3e-17 62.1 12.7 5.2e-06 26.1 0.0 6.5 8 0 0 8 8 8 3 WD domain, G-beta repeat U-box PF04564.10 EMD64896.1 - 0.00034 20.4 0.0 0.00084 19.2 0.0 1.6 2 0 0 2 2 2 1 U-box domain PQQ_3 PF13570.1 EMD64896.1 - 0.00048 20.3 2.7 0.23 11.7 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 EMD64896.1 - 0.0039 15.4 0.0 0.023 12.9 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EMD64896.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Hira PF07569.6 EMD64896.1 - 0.026 13.7 0.0 0.65 9.1 0.0 2.9 2 1 0 2 2 2 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 EMD64896.1 - 0.033 12.9 0.4 0.076 11.8 0.3 1.6 1 1 0 1 1 1 0 Coatomer WD associated region Kelch_4 PF13418.1 EMD64896.1 - 0.46 10.2 1.9 0.87 9.4 0.2 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-RING_5 PF14634.1 EMD64897.1 - 0.0063 16.2 5.8 0.01 15.5 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMD64897.1 - 0.036 13.8 2.5 0.062 13.1 1.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EMD64897.1 - 0.12 12.0 2.5 0.25 11.0 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PQQ PF01011.16 EMD64897.1 - 0.14 11.6 0.0 0.41 10.2 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat zf-C3HC4_2 PF13923.1 EMD64897.1 - 0.17 11.9 6.8 0.43 10.6 4.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMD64897.1 - 0.83 9.5 5.7 2.1 8.2 4.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger PTPLA PF04387.9 EMD64898.1 - 1.6e-51 174.0 8.4 2.2e-51 173.5 5.9 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CMD PF02627.15 EMD64899.1 - 1.7e-06 27.7 0.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF3115 PF11312.3 EMD64900.1 - 6.2e-103 343.9 0.1 7.6e-103 343.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Dot_icm_IcmQ PF09475.5 EMD64900.1 - 0.075 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF3309 PF11752.3 EMD64901.1 - 0.00037 20.2 0.5 0.00052 19.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) Glycophorin_A PF01102.13 EMD64901.1 - 0.0094 15.7 0.2 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Glycophorin A DUF805 PF05656.9 EMD64901.1 - 0.026 14.3 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DAG1 PF05454.6 EMD64901.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) ODV-E18 PF10717.4 EMD64901.1 - 0.031 13.6 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Herpes_gE PF02480.11 EMD64901.1 - 0.08 11.1 0.0 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4446 PF14584.1 EMD64901.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.1 EMD64901.1 - 0.15 12.4 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 EMD64902.1 - 1.4e-34 119.3 21.6 2.1e-34 118.8 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EMD64902.1 - 0.041 13.0 3.7 0.078 12.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF1469 PF07332.6 EMD64902.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DHDPS PF00701.17 EMD64903.1 - 1.9e-39 135.0 0.0 2.2e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 EMD64904.1 - 1.2e-26 93.2 1.2 1.7e-26 92.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD64905.1 - 3.8e-08 33.0 10.2 6.2e-08 32.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAXi_N PF14543.1 EMD64905.1 - 0.0072 16.2 1.9 0.011 15.6 1.3 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal LysM PF01476.15 EMD64907.1 - 3.6e-29 100.3 0.3 3.9e-11 42.6 0.0 3.2 3 0 0 3 3 3 3 LysM domain EutB PF06751.6 EMD64907.1 - 0.1 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) UPF0052 PF01933.13 EMD64908.1 - 3.9e-52 177.4 0.0 4.8e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF4051 PF13260.1 EMD64909.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) COMPASS-Shg1 PF05205.7 EMD64910.1 - 6.3e-16 58.5 0.0 6.3e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DOT1 PF08123.8 EMD64911.1 - 8.2e-56 188.5 0.0 1.1e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EMD64911.1 - 0.033 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3671 PF12420.3 EMD64912.1 - 0.36 10.8 2.6 0.77 9.7 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function BAF1_ABF1 PF04684.8 EMD64913.1 - 0.002 17.0 1.9 0.0028 16.5 1.3 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 EMD64913.1 - 0.035 13.5 22.0 0.047 13.0 15.3 1.4 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EMD64913.1 - 0.3 10.7 8.2 0.43 10.2 5.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EMD64913.1 - 0.6 8.2 17.1 0.68 8.1 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3994 PF13159.1 EMD64913.1 - 1.6 9.0 6.3 5.2 7.3 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) RhoGAP PF00620.22 EMD64914.1 - 4.1e-36 123.8 0.0 6.4e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 EMD64914.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family zf-Tim10_DDP PF02953.10 EMD64916.1 - 3.3e-21 74.3 6.4 4.3e-21 73.9 4.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMD64916.1 - 0.0025 17.2 5.9 0.0039 16.6 4.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) F-box-like PF12937.2 EMD64917.1 - 0.0015 18.1 0.7 0.0015 18.1 0.5 2.9 4 1 0 4 4 4 1 F-box-like F-box PF00646.28 EMD64917.1 - 0.084 12.5 4.0 1.2 8.8 0.1 3.7 4 0 0 4 4 4 0 F-box domain Asp_Glu_race PF01177.17 EMD64918.1 - 1.1e-24 87.5 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase UPRTase PF14681.1 EMD64920.1 - 4.2e-73 244.9 0.0 4.8e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMD64920.1 - 9.6e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EMD64920.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CRCB PF02537.10 EMD64921.1 - 2.3e-28 98.4 28.7 1.1e-20 73.6 6.5 3.6 3 1 0 3 3 3 2 CrcB-like protein zf-CHY PF05495.7 EMD64922.1 - 1.2e-14 54.1 11.2 1.7e-14 53.7 7.8 1.1 1 0 0 1 1 1 1 CHY zinc finger DUF3133 PF11331.3 EMD64922.1 - 0.01 15.4 0.1 0.01 15.4 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3133) Mu-like_Com PF10122.4 EMD64922.1 - 0.027 13.5 0.4 0.065 12.2 0.3 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Cytochrome_C7 PF14522.1 EMD64922.1 - 0.42 10.2 9.3 0.13 11.8 4.5 1.6 1 1 0 1 1 1 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 EMD64922.1 - 1.4 8.4 6.7 0.17 11.4 0.8 2.2 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.1 EMD64922.1 - 4.7 7.6 9.7 9.7 6.6 6.7 1.6 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.2 EMD64922.1 - 5.3 6.9 10.4 48 3.8 7.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon TIM PF00121.13 EMD64923.1 - 2.1e-90 302.0 0.3 2.3e-90 301.9 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EMD64923.1 - 0.01 15.1 0.0 0.023 13.9 0.0 1.5 1 1 0 1 1 1 0 CutC family BRX_N PF13713.1 EMD64923.1 - 0.64 9.5 0.1 0.64 9.5 0.1 3.0 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain L51_S25_CI-B8 PF05047.11 EMD64924.1 - 2e-13 49.8 0.0 3.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EMD64925.1 - 3.6e-32 110.5 1.4 6.3e-32 109.7 0.9 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EMD64925.1 - 3.1e-16 58.7 0.1 6.4e-16 57.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD64925.1 - 3e-12 46.3 0.0 4.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD64925.1 - 7.8e-08 32.0 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1308 PF07000.6 EMD64926.1 - 1.5e-55 188.3 0.0 2.1e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) SRP9-21 PF05486.7 EMD64927.1 - 2.6e-29 100.7 0.4 4.2e-29 100.1 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Aminotran_1_2 PF00155.16 EMD64929.1 - 2.1e-58 198.0 0.0 2.8e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMD64929.1 - 0.012 14.7 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase Homeobox PF00046.24 EMD64931.1 - 1.2e-19 69.6 4.5 2.3e-19 68.7 3.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMD64931.1 - 0.00071 19.2 0.9 0.0018 17.8 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF3722 PF12519.3 EMD64933.1 - 1.3e-95 319.5 0.2 1.6e-95 319.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EMD64933.1 - 4e-07 29.6 0.0 0.033 13.4 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic porin Ribosomal_L10 PF00466.15 EMD64934.1 - 6.9e-19 67.6 0.1 1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DDHD PF02862.12 EMD64935.1 - 1.8 8.3 9.0 2.2 8.0 6.3 1.1 1 0 0 1 1 1 0 DDHD domain MFS_1 PF07690.11 EMD64936.1 - 1.5e-35 122.5 23.7 1.5e-35 122.5 16.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily A_deaminase PF00962.17 EMD64937.1 - 3.8e-34 118.0 0.1 8.7e-34 116.9 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.27 EMD64938.1 - 2e-50 166.9 21.6 2.1e-08 33.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMD64938.1 - 8.1e-05 22.4 0.0 0.027 14.1 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMD64938.1 - 0.12 10.6 0.0 0.26 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 EMD64938.1 - 0.13 12.5 0.0 28 5.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Phosducin PF02114.11 EMD64939.1 - 1.8e-14 53.0 0.0 2.7e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Phosducin SIP1 PF04938.7 EMD64939.1 - 0.053 12.8 0.0 0.63 9.3 0.0 2.2 2 1 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-MYND PF01753.13 EMD64941.1 - 4e-07 29.7 19.9 8.9e-07 28.6 13.8 1.6 1 0 0 1 1 1 1 MYND finger CorA PF01544.13 EMD64942.1 - 2.1e-24 86.0 15.9 8.7e-21 74.2 9.0 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DctQ PF04290.7 EMD64942.1 - 0.037 13.7 0.9 0.073 12.8 0.6 1.4 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component GDA1_CD39 PF01150.12 EMD64943.1 - 8.5e-94 314.4 0.0 1.1e-93 314.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EMD64943.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family p450 PF00067.17 EMD64945.1 - 1.4e-67 228.2 0.0 1.7e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C97 PF05903.9 EMD64947.1 - 7.3e-39 132.9 0.0 1.5e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EMD64947.1 - 1.6e-23 82.8 0.1 2.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EMD64947.1 - 3.5e-09 36.2 0.0 6.8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 EMD64947.1 - 0.04 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 EMD64947.1 - 0.079 13.1 0.6 0.68 10.1 0.3 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain RNase_H PF00075.19 EMD64948.1 - 1.1e-12 48.4 0.3 2.9e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 RNase H Glycos_transf_2 PF00535.21 EMD64948.1 - 0.15 11.6 0.8 0.84 9.2 0.3 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 IER PF05760.7 EMD64950.1 - 0.072 13.0 6.7 0.084 12.7 4.6 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Zn_clus PF00172.13 EMD64951.1 - 1.9e-08 34.0 9.9 4.7e-08 32.8 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3414 PF11894.3 EMD64952.1 - 0 1471.0 2.0 0 1470.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Sfi1 PF08457.5 EMD64952.1 - 0.011 14.1 0.9 0.021 13.2 0.6 1.3 1 0 0 1 1 1 0 Sfi1 spindle body protein PI3_PI4_kinase PF00454.22 EMD64953.1 - 2e-45 155.0 0.0 4.5e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EMD64953.1 - 6.6e-34 116.8 0.3 9.9e-33 113.0 0.0 3.2 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EMD64953.1 - 4.4e-11 42.0 0.0 1.5e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 FATC domain Nucleo_P87 PF07267.6 EMD64955.1 - 7.5 5.0 9.4 2.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 MAP65_ASE1 PF03999.7 EMD64956.1 - 4.8e-75 253.3 2.3 4.8e-75 253.3 1.6 2.0 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) YqcI_YcgG PF08892.6 EMD64956.1 - 0.046 13.2 0.7 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 YqcI/YcgG family EAP30 PF04157.11 EMD64956.1 - 0.17 11.0 5.3 0.36 9.9 0.0 3.1 3 0 0 3 3 3 0 EAP30/Vps36 family Baculo_PEP_C PF04513.7 EMD64956.1 - 0.24 11.2 2.0 2.2 8.1 0.2 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EMD64956.1 - 0.81 9.5 2.1 11 5.9 0.2 3.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 EMD64956.1 - 1.4 9.2 18.7 0.23 11.7 0.6 5.0 4 1 0 4 4 4 0 Spectrin repeat APG6 PF04111.7 EMD64956.1 - 7.7 5.4 21.8 1.1 8.1 0.7 3.4 3 1 0 3 3 3 0 Autophagy protein Apg6 Bac_rhamnosid PF05592.6 EMD64957.1 - 4.5e-27 94.4 2.2 1.5e-24 86.1 1.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EMD64957.1 - 1.6e-05 23.8 0.9 2.2e-05 23.2 0.6 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 EMD64957.1 - 0.00024 19.9 1.8 0.0004 19.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Vps16_N PF04841.8 EMD64958.1 - 5.8e-97 324.8 0.0 7.8e-97 324.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EMD64958.1 - 8.9e-77 258.1 0.1 1.6e-76 257.3 0.1 1.3 1 1 0 1 1 1 1 Vps16, C-terminal region HTH_23 PF13384.1 EMD64959.1 - 8.3e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EMD64959.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 EMD64959.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 EMD64959.1 - 0.023 14.8 0.4 0.035 14.2 0.3 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.1 EMD64959.1 - 0.026 14.5 0.2 0.058 13.4 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.11 EMD64959.1 - 0.13 11.8 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain GerE PF00196.14 EMD64959.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Kinesin PF00225.18 EMD64960.1 - 1e-111 372.8 0.0 1.4e-111 372.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Shugoshin_N PF07558.6 EMD64960.1 - 0.0073 16.0 0.5 0.018 14.7 0.3 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region CCDC155 PF14662.1 EMD64960.1 - 0.022 14.3 7.7 0.043 13.4 5.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Mnd1 PF03962.10 EMD64960.1 - 0.025 14.2 1.1 0.051 13.2 0.7 1.5 1 0 0 1 1 1 0 Mnd1 family bZIP_1 PF00170.16 EMD64960.1 - 0.033 14.1 0.3 0.033 14.1 0.2 2.5 2 1 1 3 3 2 0 bZIP transcription factor DUF87 PF01935.12 EMD64960.1 - 0.062 13.1 2.2 0.37 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Spc7 PF08317.6 EMD64960.1 - 0.13 10.9 3.6 0.2 10.2 2.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.6 EMD64960.1 - 0.19 12.1 3.3 0.58 10.5 2.3 1.8 1 0 0 1 1 1 0 Cytochrome b562 TMF_DNA_bd PF12329.3 EMD64960.1 - 0.38 10.5 4.6 0.75 9.6 0.1 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EMD64960.1 - 0.98 9.7 9.5 0.61 10.4 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EMD64960.1 - 3.1 7.3 6.4 3.4 7.2 0.1 3.1 2 1 0 3 3 3 0 Septum formation initiator SpoU_methylase PF00588.14 EMD64961.1 - 6.4e-22 77.9 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family BTB PF00651.26 EMD64962.1 - 7.7e-09 35.5 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2256 PF10013.4 EMD64962.1 - 0.099 12.4 2.1 0.25 11.1 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3342 PF11822.3 EMD64962.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) cEGF PF12662.2 EMD64963.1 - 0.0021 17.6 3.6 0.0021 17.6 2.5 2.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like Ank_2 PF12796.2 EMD64964.1 - 4.9e-18 65.2 2.8 9.9e-08 32.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD64964.1 - 6.8e-16 57.9 3.3 3.9e-07 30.0 0.2 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD64964.1 - 3.1e-14 51.9 12.4 1.4e-09 37.3 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMD64964.1 - 1.6e-12 47.5 1.2 1.7e-08 34.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD64964.1 - 6.4e-10 38.3 2.9 0.00037 20.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.1 EMD64964.1 - 4.1e-07 30.1 0.2 6.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD64964.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EMD64964.1 - 0.0049 17.0 0.0 0.019 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3365 PF11845.3 EMD64964.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Prothymosin PF03247.9 EMD64965.1 - 0.14 12.2 14.2 0.23 11.6 9.9 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Glyco_hydro_61 PF03443.9 EMD64966.1 - 3.8e-35 121.6 0.0 5.2e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 S1 PF00575.18 EMD64967.1 - 3.6e-72 238.4 32.7 6.2e-12 45.4 1.7 13.0 13 1 0 13 13 13 11 S1 RNA binding domain Suf PF05843.9 EMD64967.1 - 0.00014 21.7 6.3 0.015 15.0 0.0 4.1 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) PPR PF01535.15 EMD64967.1 - 0.00017 21.3 1.7 0.034 14.1 0.1 3.7 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.1 EMD64967.1 - 0.00023 21.4 0.3 0.68 10.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD64967.1 - 0.0033 17.9 0.3 2.3 9.0 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat S1_2 PF13509.1 EMD64967.1 - 0.0067 16.3 0.5 0.63 9.9 0.0 3.5 3 0 0 3 3 3 1 S1 domain TPR_16 PF13432.1 EMD64967.1 - 0.014 16.0 0.1 4.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMD64967.1 - 0.027 13.5 1.1 0.12 11.4 0.4 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 EMD64967.1 - 0.053 13.5 1.5 0.37 10.7 0.1 2.8 2 0 0 2 2 2 0 PPR repeat family Mad3_BUB1_I PF08311.7 EMD64967.1 - 0.073 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 PPR_3 PF13812.1 EMD64967.1 - 0.078 13.3 0.9 13 6.3 0.0 3.8 4 1 0 4 4 2 0 Pentatricopeptide repeat domain YajC PF02699.10 EMD64967.1 - 0.58 9.8 4.3 17 5.1 0.0 4.8 5 0 0 5 5 5 0 Preprotein translocase subunit EXOSC1 PF10447.4 EMD64967.1 - 1.7 8.6 14.6 0.61 10.0 0.6 6.2 6 4 1 8 8 8 0 Exosome component EXOSC1/CSL4 WD40 PF00400.27 EMD64968.1 - 3.1e-22 77.5 11.0 1.4e-05 24.7 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EMD64968.1 - 0.00088 17.5 2.4 0.066 11.3 0.2 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EMD64968.1 - 0.087 13.1 0.1 76 3.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Glyco_hydro_61 PF03443.9 EMD64969.1 - 1.2e-53 182.1 0.8 1.4e-53 181.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transp_cyt_pur PF02133.10 EMD64970.1 - 3.8e-143 477.2 34.6 4.4e-143 476.9 24.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rick_17kDa_Anti PF05433.10 EMD64972.1 - 0.00025 20.6 13.5 0.0004 19.9 9.3 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain PAPA-1 PF04795.7 EMD64973.1 - 0.0086 16.7 0.1 0.025 15.2 0.1 1.8 1 0 0 1 1 1 1 PAPA-1-like conserved region Syndecan PF01034.15 EMD64973.1 - 0.052 13.1 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.7 EMD64973.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family DCP2 PF05026.8 EMD64974.1 - 2.1e-35 120.4 1.5 3.9e-35 119.6 1.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EMD64974.1 - 8.2e-17 61.1 0.1 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SUZ PF12752.2 EMD64974.1 - 7.8 7.1 7.4 8.5 6.9 1.0 3.3 1 1 2 3 3 3 0 SUZ domain DUF4112 PF13430.1 EMD64975.1 - 3.5e-28 97.6 0.6 4.6e-28 97.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PAP2_3 PF14378.1 EMD64977.1 - 5.3e-18 65.2 18.4 6.5e-10 38.8 0.5 3.6 2 1 1 3 3 3 3 PAP2 superfamily CDC14 PF08045.6 EMD64978.1 - 1e-91 306.6 0.0 1.3e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Sod_Cu PF00080.15 EMD64978.1 - 8.8e-16 58.3 0.1 1.8e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) UT PF03253.9 EMD64978.1 - 0.042 12.7 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Urea transporter Dak1 PF02733.12 EMD64979.1 - 4.7e-108 360.6 0.1 6.9e-108 360.0 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMD64979.1 - 5.6e-36 123.8 0.8 9.4e-36 123.1 0.6 1.4 1 0 0 1 1 1 1 DAK2 domain PIG-F PF06699.6 EMD64980.1 - 9.8e-54 182.1 5.1 1.2e-53 181.8 3.5 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.1 EMD64980.1 - 0.0038 16.6 2.4 0.15 11.5 0.1 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 EMD64980.1 - 0.041 13.9 2.9 1.7 8.8 0.3 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide TauE PF01925.14 EMD64980.1 - 0.13 11.7 13.3 0.051 13.0 6.2 2.0 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Gly-zipper_Omp PF13488.1 EMD64980.1 - 0.13 11.9 7.3 1.2 8.8 5.1 2.2 1 1 0 1 1 1 0 Glycine zipper PHO4 PF01384.15 EMD64980.1 - 0.27 9.8 5.1 0.55 8.8 3.6 1.6 1 1 0 1 1 1 0 Phosphate transporter family Rick_17kDa_Anti PF05433.10 EMD64980.1 - 0.28 10.8 8.7 2.5 7.8 1.2 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain ATPase_gene1 PF09527.5 EMD64980.1 - 4.2 7.2 12.5 7.9 6.3 0.1 3.3 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) Translin PF01997.11 EMD64981.1 - 4.2e-54 183.2 0.0 4.8e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 EMD64981.1 - 0.059 13.1 0.1 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Hr1 repeat PLU-1 PF08429.6 EMD64981.1 - 0.097 11.5 0.3 0.17 10.7 0.1 1.4 1 1 0 1 1 1 0 PLU-1-like protein DUF2422 PF10337.4 EMD64981.1 - 0.19 10.4 0.2 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Chs3p PF12271.3 EMD64984.1 - 2.2e-137 456.8 19.3 2.5e-137 456.7 13.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 EMD64984.1 - 0.026 14.4 0.7 0.026 14.4 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) FAD_binding_3 PF01494.14 EMD64985.1 - 4.4e-71 239.7 0.0 9e-71 238.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMD64985.1 - 1.4e-44 151.7 0.0 2.3e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EMD64985.1 - 0.0063 15.3 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.9 EMD64985.1 - 0.0075 16.1 0.1 0.094 12.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD64985.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ADH_zinc_N PF00107.21 EMD64989.1 - 4.4e-27 94.2 0.0 6.6e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD64989.1 - 1.1e-26 92.6 2.2 1.8e-26 91.9 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD64989.1 - 2.6e-08 34.8 0.0 4.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMD64989.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 EMD64989.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMD64989.1 - 0.046 12.7 0.2 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.12 EMD64989.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Response_reg PF00072.19 EMD64990.1 - 7.5e-26 90.3 0.6 2e-25 88.9 0.4 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMD64990.1 - 1.5e-21 76.1 0.0 4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EMD64990.1 - 6.2e-13 49.0 0.0 2.4e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EMD64990.1 - 5.3e-07 29.5 2.6 5.8e-07 29.4 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 EMD64990.1 - 1.1e-06 28.2 0.0 0.0071 16.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EMD64990.1 - 4.2e-06 26.5 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EMD64990.1 - 4.9e-05 23.3 0.0 0.61 10.1 0.0 3.4 2 1 1 3 3 3 2 PAS fold Neural_ProG_Cyt PF06567.6 EMD64991.1 - 0.24 11.5 1.3 0.68 10.0 0.2 2.0 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain DUF972 PF06156.8 EMD64991.1 - 1.7 9.0 12.6 1.2 9.5 6.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1515 PF07439.6 EMD64991.1 - 8.7 6.1 8.1 0.76 9.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TRAPP PF04051.11 EMD64992.1 - 1.6e-35 121.8 0.0 2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Thioredoxin PF00085.15 EMD64993.1 - 2.1e-26 91.5 0.0 2.1e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EMD64993.1 - 1.3e-09 37.9 0.2 5.5e-07 29.6 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD64993.1 - 7.8e-09 35.7 2.4 1.4e-08 34.8 0.2 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMD64993.1 - 0.00023 20.8 1.1 0.32 10.6 0.1 2.6 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EMD64993.1 - 0.0004 20.3 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMD64993.1 - 0.0014 18.1 0.9 0.26 10.8 0.2 2.3 1 1 1 2 2 2 2 Redoxin DUF953 PF06110.6 EMD64993.1 - 0.018 14.4 1.2 0.062 12.7 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.1 EMD64993.1 - 0.02 14.4 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.6 EMD64993.1 - 0.056 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EMD64993.1 - 0.09 12.3 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EMD64993.1 - 0.16 11.9 3.1 0.67 9.9 0.0 2.7 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.15 EMD64993.1 - 6.7 6.2 7.0 1.8 8.0 0.1 2.6 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin PF00085.15 EMD64994.1 - 2.4e-62 207.0 0.1 3.5e-31 106.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EMD64994.1 - 1.5e-21 76.7 1.3 3.6e-21 75.5 0.4 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EMD64994.1 - 1.4e-19 70.3 0.3 3.2e-08 33.7 0.0 3.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMD64994.1 - 8.3e-13 48.1 0.0 2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EMD64994.1 - 6e-12 45.5 0.1 9e-05 22.5 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EMD64994.1 - 2.5e-08 33.6 0.3 0.0017 18.0 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 EMD64994.1 - 1.1e-07 31.8 0.4 0.00013 21.9 0.0 2.7 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 EMD64994.1 - 3.5e-07 30.2 0.5 0.00044 20.0 0.0 3.0 3 1 1 4 4 4 2 Thioredoxin-like domain Redoxin PF08534.5 EMD64994.1 - 3.1e-06 26.8 0.3 0.02 14.4 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EMD64994.1 - 4e-06 26.4 0.0 0.0038 16.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 EMD64994.1 - 0.0001 22.3 1.4 0.52 10.2 0.2 3.9 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 EMD64994.1 - 0.00047 19.9 0.0 0.055 13.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 EMD64994.1 - 0.0042 16.9 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EMD64994.1 - 0.14 12.1 1.6 10 6.2 0.1 3.2 2 2 0 2 2 2 0 Glutaredoxin Ribosomal_S18 PF01084.15 EMD64994.1 - 0.15 11.9 0.1 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S18 HSBP1 PF06825.7 EMD64995.1 - 2.5e-19 68.5 0.1 2.9e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EMD64995.1 - 0.0011 18.2 0.7 0.15 11.4 0.1 2.1 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 EMD64995.1 - 0.012 15.4 0.6 0.014 15.2 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SRA1 PF07304.6 EMD64995.1 - 0.035 13.8 0.1 0.037 13.7 0.1 1.0 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) NPV_P10 PF05531.7 EMD64995.1 - 0.08 13.2 0.4 0.16 12.2 0.2 1.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein STAT_int PF02865.12 EMD64995.1 - 0.082 12.8 0.1 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 STAT protein, protein interaction domain Corona_S2 PF01601.11 EMD64995.1 - 0.09 10.8 0.1 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2884 PF11101.3 EMD64995.1 - 0.16 11.3 0.2 0.33 10.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Ebp2 PF05890.7 EMD64996.1 - 5e-96 321.1 19.3 5e-96 321.1 13.3 2.4 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Ub-Mut7C PF14451.1 EMD64996.1 - 0.079 12.4 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin ADH_zinc_N_2 PF13602.1 EMD64997.1 - 3.9e-26 92.4 0.0 6.7e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD64997.1 - 3.6e-14 52.4 0.0 7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD64997.1 - 2.2e-07 30.6 0.9 2.3e-05 24.0 0.0 3.0 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Lep_receptor_Ig PF06328.6 EMD64997.1 - 0.024 14.4 0.0 8.8 6.2 0.0 2.4 1 1 1 2 2 2 0 Ig-like C2-type domain NAD_binding_10 PF13460.1 EMD64997.1 - 0.06 13.3 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding BAR PF03114.13 EMD64998.1 - 0.19 11.2 3.6 0.07 12.6 0.5 1.7 2 0 0 2 2 2 0 BAR domain Fungal_trans PF04082.13 EMD65000.1 - 6.7e-30 103.8 1.2 6.7e-30 103.8 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65000.1 - 1.8e-07 30.9 9.0 2.8e-07 30.3 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EMD65000.1 - 2e-06 27.6 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Cript PF10235.4 EMD65000.1 - 0.064 13.6 3.6 0.14 12.5 2.5 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT AAA_33 PF13671.1 EMD65001.1 - 1.6e-06 28.0 0.3 0.015 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EMD65001.1 - 1.1e-05 24.3 0.0 1.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EMD65001.1 - 4.3e-05 22.6 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EMD65001.1 - 0.00021 21.5 0.1 0.0021 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD65001.1 - 0.00028 21.7 0.5 0.0017 19.1 0.4 2.0 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EMD65001.1 - 0.00084 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EMD65001.1 - 0.0013 18.7 0.1 0.0019 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 EMD65001.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 EMD65001.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 EMD65001.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.5 EMD65001.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EMD65001.1 - 0.031 13.9 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 EMD65001.1 - 0.034 13.5 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF815 PF05673.8 EMD65001.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EMD65001.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EMD65001.1 - 0.12 11.8 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMD65001.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMD65001.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EMD65001.1 - 0.13 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sugar_tr PF00083.19 EMD65002.1 - 4.8e-122 407.7 23.0 8.4e-122 406.9 16.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65002.1 - 6.3e-22 77.7 51.8 1.9e-11 43.2 18.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.23 EMD65004.1 - 1.6e-06 27.4 0.0 3.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD65004.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain HET PF06985.6 EMD65005.1 - 2.4e-16 60.1 0.3 2.9e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy PF03171.15 EMD65006.1 - 0.00019 21.6 0.0 0.00057 20.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD65006.1 - 0.0046 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GCV_T PF01571.16 EMD65007.1 - 1.5e-19 70.1 0.0 3.6e-16 59.1 0.0 2.2 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMD65007.1 - 2.9e-05 24.0 0.1 5.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Lung_7-TM_R PF06814.8 EMD65008.1 - 1.9e-68 230.6 19.8 2.4e-68 230.2 13.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EMD65008.1 - 0.59 10.3 18.2 2.3 8.3 1.6 3.8 2 1 2 4 4 4 0 PrgI family protein PBP1_TM PF14812.1 EMD65008.1 - 8 6.8 8.4 19 5.6 2.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EMD65008.1 - 9 5.7 9.4 21 4.5 6.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2392 PF10288.4 EMD65009.1 - 6e-30 103.7 0.0 1.1e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) zf-FPG_IleRS PF06827.9 EMD65009.1 - 0.2 11.3 2.8 0.48 10.1 1.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS HA2 PF04408.18 EMD65010.1 - 3.1e-20 72.0 1.3 1e-19 70.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMD65010.1 - 7e-17 61.3 0.0 1.5e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 EMD65010.1 - 3.1e-12 46.3 0.0 6.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.26 EMD65010.1 - 2.1e-11 43.5 0.0 5.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD65010.1 - 2.7e-09 36.7 0.3 5.3e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMD65010.1 - 0.00012 22.1 0.2 0.00035 20.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 EMD65010.1 - 0.0039 17.4 0.1 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EMD65010.1 - 0.008 15.6 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMD65010.1 - 0.024 14.6 0.4 0.024 14.6 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EMD65010.1 - 0.027 13.3 0.1 0.065 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EMD65010.1 - 0.072 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Aldo_ket_red PF00248.16 EMD65010.1 - 0.13 11.0 0.2 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Aldo/keto reductase family AAA_23 PF13476.1 EMD65010.1 - 0.22 11.8 2.6 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain zf-CCCH PF00642.19 EMD65011.1 - 0.0028 17.2 12.8 0.066 12.9 0.4 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BPL_N PF09825.4 EMD65011.1 - 0.044 12.5 0.3 0.064 12.0 0.2 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DERM PF14704.1 EMD65011.1 - 0.075 12.9 2.8 0.33 10.9 0.1 2.9 3 0 0 3 3 3 0 Dermatopontin DUF2187 PF09953.4 EMD65011.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) TRAP_alpha PF03896.11 EMD65012.1 - 5.9e-06 25.4 1.5 6.1e-05 22.1 1.0 2.0 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit MFS_1 PF07690.11 EMD65014.1 - 5e-31 107.6 36.4 7e-31 107.2 25.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 EMD65015.1 - 3.2e-16 59.9 0.0 5.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMD65015.1 - 3.3e-06 26.8 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DivIC PF04977.10 EMD65016.1 - 0.6 9.6 4.3 0.81 9.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Pam16 PF03656.8 EMD65016.1 - 1.3 8.8 6.2 1 9.1 1.4 2.8 2 0 0 2 2 2 0 Pam16 DUF3138 PF11336.3 EMD65016.1 - 3.9 5.5 11.2 1.2 7.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) RRM_6 PF14259.1 EMD65017.1 - 2e-14 53.2 0.0 3.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD65017.1 - 5.4e-13 48.3 0.1 9.3e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD65017.1 - 2.4e-06 27.2 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHOCT PF09851.4 EMD65018.1 - 0.11 12.0 0.6 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain DivIC PF04977.10 EMD65018.1 - 0.61 9.6 3.8 7.1 6.1 2.0 2.3 2 0 0 2 2 2 0 Septum formation initiator F-box PF00646.28 EMD65020.1 - 8e-06 25.3 0.2 8e-06 25.3 0.1 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EMD65020.1 - 0.00077 19.1 0.1 0.00077 19.1 0.1 2.2 3 0 0 3 3 3 1 F-box-like DUF2614 PF11023.3 EMD65020.1 - 0.017 14.9 0.5 0.025 14.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) DZR PF12773.2 EMD65020.1 - 0.61 9.9 5.9 0.98 9.2 2.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon Dickkopf_N PF04706.7 EMD65020.1 - 5.9 7.1 10.1 15 5.8 3.8 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region PIG-L PF02585.12 EMD65021.1 - 2.8e-24 86.0 0.1 4.2e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SLAC1 PF03595.12 EMD65023.1 - 4.4e-88 295.0 49.6 5e-88 294.9 34.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3270 PF11674.3 EMD65023.1 - 1.9 8.5 4.5 5.4 7.1 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Glyco_hydro_61 PF03443.9 EMD65024.1 - 3.1e-62 210.2 0.0 3.6e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.17 EMD65024.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain PGP_phosphatase PF09419.5 EMD65025.1 - 3.5e-67 224.9 0.0 4.1e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EMD65025.1 - 3.1e-05 23.5 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMD65025.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LSM PF01423.17 EMD65026.1 - 1.1e-14 53.6 0.2 1.5e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD65026.1 - 0.11 12.4 0.1 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EMD65027.1 - 1.2e-13 51.4 6.5 1e-12 48.5 4.5 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 P_gingi_FimA PF06321.6 EMD65027.1 - 0.01 15.0 0.7 0.017 14.3 0.5 1.2 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) Methyltransf_23 PF13489.1 EMD65028.1 - 8.6e-16 58.0 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD65028.1 - 1.1e-15 57.5 0.0 1e-13 51.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD65028.1 - 2.2e-13 50.5 0.0 5e-13 49.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD65028.1 - 2e-12 47.4 0.0 1.4e-11 44.7 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD65028.1 - 4.7e-09 36.8 0.0 8.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD65028.1 - 1.7e-06 28.3 0.0 4.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD65028.1 - 0.00017 21.5 0.1 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD65028.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EMD65028.1 - 0.0029 17.2 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMD65028.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EMD65028.1 - 0.006 16.0 0.4 0.055 12.9 0.0 2.5 1 1 1 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EMD65028.1 - 0.021 13.9 0.0 0.43 9.6 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EMD65028.1 - 0.04 12.9 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.6 EMD65028.1 - 0.065 11.9 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EMD65028.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EMD65028.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) vWA-TerF-like PF10138.4 EMD65029.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EMD65029.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain Extensin_2 PF04554.8 EMD65029.1 - 0.39 10.6 59.6 0.089 12.6 15.7 3.6 2 1 1 3 3 3 0 Extensin-like region Ribonuclease PF00545.15 EMD65031.1 - 3.9e-20 71.7 1.9 4.9e-20 71.4 1.0 1.3 1 1 0 1 1 1 1 ribonuclease Bestrophin PF01062.16 EMD65032.1 - 5e-42 143.8 0.3 1.4e-24 86.5 0.0 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel YrvL PF14184.1 EMD65032.1 - 0.5 10.1 4.0 0.12 12.1 0.5 1.6 2 0 0 2 2 2 0 Regulatory protein YrvL FHA PF00498.21 EMD65033.1 - 1.5e-16 60.2 0.0 3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EMD65033.1 - 2.1e-08 33.8 8.4 3.6e-08 33.1 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD65033.1 - 0.00017 21.6 5.0 0.00033 20.7 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD65033.1 - 0.0043 16.6 7.6 0.0078 15.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EMD65033.1 - 0.013 15.2 4.1 0.024 14.3 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EMD65033.1 - 0.013 15.3 2.9 0.023 14.5 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMD65033.1 - 0.043 13.5 5.0 0.077 12.7 3.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD65033.1 - 0.9 9.6 10.0 1.7 8.7 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M16_C PF05193.16 EMD65034.1 - 1.9e-48 164.6 0.0 3.8e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMD65034.1 - 2.1e-39 134.6 0.0 5.2e-39 133.3 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HET PF06985.6 EMD65035.1 - 1.5e-22 80.2 6.0 5.1e-20 72.0 4.2 3.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMD65035.1 - 2.6e-11 43.4 0.1 6.2e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD65035.1 - 4.5e-05 23.5 0.0 0.0034 17.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMD65035.1 - 0.00098 19.0 0.1 0.014 15.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD65035.1 - 0.0042 17.2 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 EMD65035.1 - 0.0091 16.1 0.0 0.041 14.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMD65035.1 - 0.014 14.2 0.1 0.054 12.3 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EMD65035.1 - 0.047 13.8 0.1 0.44 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EMD65035.1 - 0.047 12.7 0.7 9.3 5.2 0.1 2.7 3 0 0 3 3 3 0 KaiC HTH_20 PF12840.2 EMD65035.1 - 0.081 12.7 0.0 0.49 10.2 0.0 2.4 1 0 0 1 1 1 0 Helix-turn-helix domain Mpv17_PMP22 PF04117.7 EMD65037.1 - 1.1e-12 47.3 1.4 4.5e-11 42.2 0.8 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.10 EMD65037.1 - 0.069 11.8 2.6 0.094 11.4 1.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) UPF0154 PF03672.8 EMD65037.1 - 0.07 12.7 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SprT-like PF10263.4 EMD65038.1 - 2.4e-08 33.7 1.6 5.6e-08 32.5 1.1 1.6 1 1 0 1 1 1 1 SprT-like family GAS PF13851.1 EMD65038.1 - 0.0023 17.1 1.2 0.029 13.5 2.1 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding EMP24_GP25L PF01105.19 EMD65038.1 - 0.086 12.5 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Bcr-Abl_Oligo PF09036.5 EMD65038.1 - 0.18 11.7 2.9 0.26 11.2 0.4 2.4 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain TPR_12 PF13424.1 EMD65040.1 - 5e-27 93.6 11.3 3.7e-08 33.1 0.6 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMD65040.1 - 5.3e-20 70.6 9.1 0.0014 18.5 0.0 8.0 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMD65040.1 - 1.2e-13 49.8 9.2 0.0062 16.3 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD65040.1 - 6.7e-13 48.9 0.1 0.0011 19.5 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD65040.1 - 4.1e-12 45.5 3.1 0.00023 20.7 0.0 5.0 4 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EMD65040.1 - 4.6e-10 38.6 9.1 0.038 13.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD65040.1 - 3.9e-08 33.5 0.4 0.053 13.8 0.0 5.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD65040.1 - 2e-07 31.0 6.2 6.3 7.7 0.0 7.5 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD65040.1 - 3.8e-07 29.4 17.4 0.045 13.5 0.0 8.3 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD65040.1 - 2.8e-05 23.9 0.0 24 5.4 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD65040.1 - 4.3e-05 22.9 7.1 2.1 8.3 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMD65040.1 - 0.00017 21.6 1.8 11 6.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.15 EMD65040.1 - 0.00075 19.3 8.8 11 6.2 0.0 5.9 6 0 0 6 6 5 0 PPR repeat DUF3366 PF11846.3 EMD65040.1 - 0.026 14.4 0.9 66 3.2 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3366) Alb1 PF09135.6 EMD65040.1 - 0.47 11.0 3.6 0.59 10.7 0.7 2.5 2 0 0 2 2 2 0 Alb1 TnpV PF14198.1 EMD65041.1 - 0.0078 16.0 3.6 0.24 11.3 2.6 2.0 1 1 0 1 1 1 1 Transposon-encoded protein TnpV DUF342 PF03961.8 EMD65041.1 - 0.015 13.7 0.7 0.016 13.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LDB19 PF13002.2 EMD65043.1 - 5.4e-52 176.0 0.3 1.1e-51 175.1 0.2 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EMD65043.1 - 1.3e-05 25.0 0.0 4.4e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L22e PF01776.12 EMD65044.1 - 4.1e-50 168.4 2.7 4.8e-50 168.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1939 PF09154.5 EMD65044.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) SQS_PSY PF00494.14 EMD65045.1 - 4.8e-47 160.4 0.0 7.5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DNA_pol_delta_4 PF04081.8 EMD65045.1 - 0.014 15.6 0.0 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 DUF3526 PF12040.3 EMD65045.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) SNF2_N PF00176.18 EMD65046.1 - 1.5e-67 227.5 0.0 2e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EMD65046.1 - 7.7e-19 67.6 0.0 2.3e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 EMD65046.1 - 5e-13 48.7 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EMD65046.1 - 1.1e-06 28.5 12.3 2.1e-06 27.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EMD65046.1 - 4.4e-05 23.3 0.1 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EMD65046.1 - 0.00053 19.5 13.3 0.001 18.6 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD65046.1 - 0.0014 18.2 10.1 0.0027 17.3 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD65046.1 - 0.0029 17.3 11.1 0.0056 16.4 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain Rrp15p PF07890.7 EMD65046.1 - 0.032 14.2 0.3 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Rrp15p zf-RING_5 PF14634.1 EMD65046.1 - 0.032 13.9 9.5 0.074 12.7 6.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Asp PF00026.18 EMD65048.1 - 5.2e-12 45.6 0.0 1.4e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 EMD65048.1 - 0.072 11.7 0.2 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Fungal_trans_2 PF11951.3 EMD65049.1 - 0.01 14.4 0.3 0.01 14.4 0.2 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMD65050.1 - 2.3e-07 29.9 0.1 4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD65051.1 - 4.5e-47 160.4 48.6 4.5e-47 160.4 33.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD65051.1 - 9.8e-10 37.2 26.8 1.3e-09 36.8 18.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 EMD65052.1 - 8.3e-23 80.4 0.9 1.3e-22 79.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD65052.1 - 6.1e-05 22.8 0.3 0.00015 21.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF1772 PF08592.6 EMD65053.1 - 1.9e-13 50.3 0.3 2.5e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short PF00106.20 EMD65054.1 - 3.2e-16 59.6 1.2 6e-16 58.8 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMD65054.1 - 7.5e-10 38.7 0.2 1.3e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 KR domain HemY_N PF07219.8 EMD65056.1 - 0.14 11.7 3.5 0.17 11.4 2.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus GTP_EFTU PF00009.22 EMD65057.1 - 3.3e-61 206.0 0.3 4.4e-61 205.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMD65057.1 - 1.2e-25 89.5 0.0 2.8e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMD65057.1 - 2.4e-16 59.6 2.1 6.3e-16 58.2 1.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD65057.1 - 4.6e-06 26.5 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMD65057.1 - 0.00011 21.7 0.5 0.00026 20.5 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EMD65057.1 - 0.00075 19.9 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EMD65057.1 - 0.0034 16.8 0.2 3.2 7.2 0.0 2.7 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EMD65057.1 - 0.029 13.5 0.2 0.084 11.9 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EMD65057.1 - 0.15 11.5 0.7 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EMD65057.1 - 0.35 10.1 2.1 9.9 5.4 0.3 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B ECH_C PF13766.1 EMD65058.1 - 2.1e-36 124.6 0.7 3.9e-36 123.7 0.2 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EMD65058.1 - 1.4e-29 103.0 0.0 6.4e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family FAD_binding_4 PF01565.18 EMD65059.1 - 1.4e-14 53.7 0.2 2.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD65059.1 - 6.4e-10 38.7 0.2 3e-09 36.6 0.0 2.3 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD65059.1 - 0.032 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DNMT1-RFD PF12047.3 EMD65061.1 - 0.0042 16.7 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Vpu PF00558.14 EMD65061.1 - 0.15 11.6 0.8 2 8.0 0.0 2.6 2 0 0 2 2 2 0 Vpu protein CAF1C_H4-bd PF12265.3 EMD65062.1 - 7.6e-19 67.3 0.0 2.1e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EMD65062.1 - 1.5e-18 65.8 13.2 5e-08 32.5 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Ras PF00071.17 EMD65063.1 - 1.8e-31 108.7 0.2 2.7e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD65063.1 - 1.9e-20 73.5 0.1 1.1e-19 71.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMD65063.1 - 1.1e-06 28.0 0.1 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD65063.1 - 1.3e-05 24.4 0.2 2.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMD65063.1 - 0.021 13.5 6.5 0.26 9.9 0.0 2.9 1 1 1 3 3 3 0 G-protein alpha subunit AAA_35 PF14516.1 EMD65063.1 - 0.022 13.3 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain EXOSC1 PF10447.4 EMD65064.1 - 3.2e-23 81.4 0.4 4.6e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EMD65064.1 - 8.4e-14 50.5 0.5 1.5e-13 49.7 0.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RA PF00788.18 EMD65065.1 - 9.6e-16 58.0 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EMD65065.1 - 2.9e-13 49.7 0.0 4.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMD65065.1 - 6e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TMF_TATA_bd PF12325.3 EMD65065.1 - 0.0055 16.4 0.1 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EMD65065.1 - 0.034 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HoxA13_N PF12284.3 EMD65065.1 - 0.07 13.2 2.1 0.19 11.9 1.5 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal DUF4140 PF13600.1 EMD65065.1 - 0.072 13.5 0.5 0.19 12.1 0.4 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Lebercilin PF15619.1 EMD65065.1 - 0.1 12.0 1.1 0.15 11.4 0.8 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease tRNA-synt_1c PF00749.16 EMD65066.1 - 0.031 12.9 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain AAA PF00004.24 EMD65067.1 - 5.1e-98 324.4 0.0 8.8e-48 161.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMD65067.1 - 1.1e-19 70.1 0.6 3.6e-19 68.4 0.4 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EMD65067.1 - 2.8e-14 53.3 0.0 8.8e-08 32.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMD65067.1 - 3e-13 49.3 0.0 7.4e-06 25.1 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMD65067.1 - 1.6e-12 47.5 0.0 6.6e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD65067.1 - 1.6e-11 44.4 0.2 0.0023 18.0 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EMD65067.1 - 1.8e-11 43.9 0.8 5.3e-06 26.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMD65067.1 - 1.9e-11 44.8 0.0 0.00052 20.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD65067.1 - 2.9e-11 43.7 0.0 0.00083 19.3 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EMD65067.1 - 1.6e-09 36.9 0.1 0.00093 18.0 0.0 2.9 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EMD65067.1 - 5.9e-09 35.6 3.5 0.02 14.2 0.0 4.6 3 2 1 5 5 4 2 AAA domain AAA_19 PF13245.1 EMD65067.1 - 8e-08 31.9 1.2 0.0043 16.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EMD65067.1 - 9.3e-08 31.6 0.1 0.0089 15.4 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EMD65067.1 - 1e-07 31.9 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMD65067.1 - 1.9e-07 30.3 0.0 0.0074 15.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 EMD65067.1 - 3.1e-07 29.7 0.6 0.19 10.8 0.0 3.4 2 1 1 3 3 3 2 KaiC Mg_chelatase PF01078.16 EMD65067.1 - 3.7e-07 29.5 0.4 0.031 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMD65067.1 - 4.5e-07 30.0 0.0 0.021 15.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.12 EMD65067.1 - 4.6e-07 29.3 0.1 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 EMD65067.1 - 3.7e-06 27.2 0.0 0.065 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EMD65067.1 - 4.9e-06 26.4 0.0 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EMD65067.1 - 8.7e-06 25.4 0.3 0.15 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 EMD65067.1 - 1.3e-05 24.2 0.0 0.018 13.9 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.1 EMD65067.1 - 1.9e-05 24.6 0.0 0.24 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EMD65067.1 - 2.5e-05 23.3 0.1 0.086 11.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EMD65067.1 - 3.4e-05 23.3 0.1 0.3 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMD65067.1 - 4.1e-05 23.3 0.1 0.92 9.1 0.1 4.0 2 2 2 4 4 4 1 Archaeal ATPase Bac_DnaA PF00308.13 EMD65067.1 - 5.5e-05 22.9 0.0 0.39 10.3 0.0 3.4 4 0 0 4 4 4 2 Bacterial dnaA protein PhoH PF02562.11 EMD65067.1 - 9.2e-05 21.7 0.3 0.29 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 EMD65067.1 - 0.00011 22.4 0.0 0.4 10.9 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EMD65067.1 - 0.00011 22.2 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EMD65067.1 - 0.00027 20.6 0.1 0.64 9.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EMD65067.1 - 0.00032 20.3 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMD65067.1 - 0.00067 19.2 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EMD65067.1 - 0.00069 18.6 0.0 0.84 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 EMD65067.1 - 0.00084 19.1 0.1 0.0039 17.0 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.1 EMD65067.1 - 0.0011 18.5 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMD65067.1 - 0.0013 17.6 0.2 0.66 8.7 0.0 2.9 4 0 0 4 4 4 1 NB-ARC domain NTPase_1 PF03266.10 EMD65067.1 - 0.0039 16.9 0.3 1.8 8.2 0.0 3.7 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EMD65067.1 - 0.0076 15.7 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EMD65067.1 - 0.02 13.9 0.5 0.92 8.4 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain IPT PF01745.11 EMD65067.1 - 0.025 13.7 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EMD65067.1 - 0.029 13.8 0.2 11 5.3 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 EMD65067.1 - 0.031 13.1 0.0 2.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EMD65067.1 - 0.089 12.2 0.7 7.3 5.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain XPG_N PF00752.12 EMD65068.1 - 0.0001 22.4 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_12 PF01670.11 EMD65068.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 DIOX_N PF14226.1 EMD65069.1 - 1.3e-22 80.4 0.0 2.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD65069.1 - 1.5e-15 57.2 0.0 4.9e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PTCB-BRCT PF12738.2 EMD65070.1 - 2.1e-48 161.9 0.5 1.3e-23 82.5 0.0 4.9 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 EMD65070.1 - 1.4e-30 105.2 0.0 3.8e-11 42.9 0.0 5.3 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.17 EMD65071.1 - 3.9e-23 82.0 0.0 1.9e-22 79.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMD65071.1 - 1.5e-09 37.8 0.0 1.3e-05 25.0 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Na_H_Exchanger PF00999.16 EMD65072.1 - 9.4e-68 228.4 22.8 1.1e-67 228.1 15.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EMD65072.1 - 4.3e-57 194.3 43.7 4.3e-57 194.3 30.3 2.8 2 1 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.1 EMD65072.1 - 0.62 9.6 0.0 0.62 9.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Fer2_3 PF13085.1 EMD65076.1 - 0.091 12.6 0.9 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_16 PF00722.16 EMD65079.1 - 7.4e-19 67.7 0.2 1.2e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RasGEF PF00617.14 EMD65080.1 - 1.1e-63 214.3 0.3 1.1e-63 214.3 0.2 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMD65080.1 - 6e-27 93.7 0.0 1.7e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EMD65080.1 - 1.6e-15 56.1 0.1 3.3e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD65080.1 - 8.6e-15 54.0 0.1 2.3e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMD65080.1 - 2.3e-12 46.2 0.1 4.9e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EMD65080.1 - 9.8e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.13 EMD65081.1 - 2.8e-16 59.1 2.6 4.5e-16 58.5 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMD65081.1 - 2e-07 30.9 13.7 0.0001 22.3 4.0 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD65081.1 - 5.2e-05 23.2 13.3 0.0041 17.3 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD65081.1 - 0.00021 21.4 14.4 0.035 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD65081.1 - 0.63 10.0 4.2 16 5.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L7Ae PF01248.21 EMD65082.1 - 1.9e-20 72.1 4.3 2.4e-19 68.6 2.9 2.2 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Zn_clus PF00172.13 EMD65083.1 - 2.2e-07 30.6 13.6 3.2e-07 30.1 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD65083.1 - 3.1e-07 29.3 0.2 4.7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EMD65084.1 - 4.9e-47 160.3 7.1 4.9e-47 160.3 4.9 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF2873 PF11395.3 EMD65084.1 - 0.074 12.6 3.7 0.28 10.7 2.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) SecY PF00344.15 EMD65085.1 - 6.2e-95 318.0 10.7 7.6e-95 317.7 7.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMD65085.1 - 2.6e-18 65.2 0.3 8.3e-18 63.6 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p LIM PF00412.17 EMD65086.1 - 5.1e-19 68.0 21.1 1e-10 41.5 2.6 2.5 3 0 0 3 3 3 2 LIM domain WRC PF08879.5 EMD65086.1 - 0.015 14.9 0.4 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 WRC NAD_binding_5 PF07994.7 EMD65087.1 - 4.6e-114 380.8 0.2 6.2e-114 380.4 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EMD65087.1 - 4.6e-45 152.0 0.7 9.8e-45 150.9 0.3 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase tRNA_anti-codon PF01336.20 EMD65088.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MIS13 PF08202.6 EMD65089.1 - 2.4e-48 164.7 0.1 5.3e-48 163.6 0.0 1.6 2 0 0 2 2 2 1 Mis12-Mtw1 protein family PS_Dcarbxylase PF02666.10 EMD65090.1 - 3.8e-53 179.8 0.0 5.5e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EMD65090.1 - 3.9e-37 125.9 0.3 1.7e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EMD65090.1 - 0.0002 21.3 0.2 0.00071 19.6 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMD65090.1 - 0.028 14.3 0.4 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain CEP76-C2 PF15627.1 EMD65090.1 - 0.034 13.6 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 CEP76 C2 domain EF-hand_1 PF00036.27 EMD65090.1 - 0.041 13.1 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 EF hand CDC45 PF02724.9 EMD65090.1 - 0.33 8.9 6.6 0.55 8.2 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein G-alpha PF00503.15 EMD65092.1 - 9e-133 442.7 1.7 1.1e-132 442.4 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMD65092.1 - 3.7e-15 55.5 2.5 2e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EMD65092.1 - 0.00044 19.7 0.0 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EMD65092.1 - 0.0017 18.7 0.7 3 8.3 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EMD65092.1 - 0.0074 15.4 3.6 0.22 10.6 0.1 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EMD65092.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMD65092.1 - 0.025 14.0 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mog1 PF04603.7 EMD65092.1 - 0.095 12.6 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Ran-interacting Mog1 protein MMR_HSR1 PF01926.18 EMD65092.1 - 0.1 12.5 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EMD65092.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DDE_Tnp_IS240 PF13610.1 EMD65095.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 DDE domain Transketolase_N PF00456.16 EMD65096.1 - 4.1e-148 492.6 0.1 5.6e-148 492.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMD65096.1 - 6.1e-44 149.6 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMD65096.1 - 5e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EMD65096.1 - 1.7e-05 23.9 0.0 0.00028 19.9 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EMD65096.1 - 8.6e-05 21.3 0.1 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.16 EMD65096.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2731 PF10806.3 EMD65097.1 - 8.4e-06 26.0 0.4 2e-05 24.8 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 EMD65097.1 - 0.00056 19.7 1.9 0.001 18.9 1.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD65097.1 - 0.0008 19.8 0.1 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EMD65097.1 - 0.0086 16.3 0.1 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Methyltransf_31 PF13847.1 EMD65098.1 - 1.8e-12 47.1 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD65098.1 - 2.3e-11 43.6 0.0 4.2e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD65098.1 - 1.4e-09 38.5 0.0 3.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD65098.1 - 5e-09 36.5 0.0 1.2e-08 35.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD65098.1 - 9.5e-09 35.6 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD65098.1 - 3.5e-08 33.7 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD65098.1 - 1.8e-05 23.9 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMD65098.1 - 5.6e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMD65098.1 - 0.0027 17.2 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.10 EMD65098.1 - 0.0043 15.8 0.0 0.01 14.6 0.0 1.5 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.1 EMD65098.1 - 0.008 15.8 0.1 0.039 13.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain CheR PF01739.13 EMD65098.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.9 EMD65098.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_28 PF02636.12 EMD65098.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMD65098.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF1264 PF06884.6 EMD65099.1 - 6.1e-71 237.3 0.0 7.3e-71 237.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF4598 PF15370.1 EMD65100.1 - 1.8e-17 63.6 2.1 1.8e-17 63.6 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) DDHD PF02862.12 EMD65100.1 - 0.44 10.3 2.2 0.76 9.5 1.5 1.4 1 1 0 1 1 1 0 DDHD domain Nop25 PF09805.4 EMD65100.1 - 0.55 10.3 12.1 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) IF4E PF01652.13 EMD65101.1 - 1.2e-35 122.5 0.6 1.4e-35 122.2 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Band_7 PF01145.20 EMD65102.1 - 5e-26 91.7 4.6 8.4e-26 90.9 3.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EMD65102.1 - 0.015 14.9 2.4 0.027 14.1 1.7 1.5 1 1 0 1 1 1 0 GatB domain zf-C2H2_4 PF13894.1 EMD65103.1 - 7.2e-06 25.9 8.8 0.1 12.9 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD65103.1 - 0.059 13.7 12.3 0.67 10.4 0.1 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type APG6 PF04111.7 EMD65103.1 - 1.1 8.2 4.0 1.6 7.7 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-R PF06729.7 EMD65103.1 - 4.9 6.8 7.6 0.15 11.7 0.8 1.7 2 0 0 2 2 2 0 Kinetochore component, CENP-R NMN_transporter PF04973.7 EMD65104.1 - 0.016 14.6 0.1 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF3671 PF12420.3 EMD65104.1 - 0.099 12.6 1.3 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function 2TM PF13239.1 EMD65104.1 - 0.15 12.1 1.7 0.99 9.5 0.1 2.0 1 1 1 2 2 2 0 2TM domain DUF4149 PF13664.1 EMD65104.1 - 0.16 12.0 0.8 0.21 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF3687 PF12459.3 EMD65104.1 - 0.22 10.7 0.2 0.22 10.7 0.2 2.2 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein GMC_oxred_N PF00732.14 EMD65105.1 - 1.3e-47 162.3 0.0 1.9e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD65105.1 - 1.3e-30 106.6 0.2 2.7e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD65105.1 - 3.7e-05 22.8 0.0 0.00018 20.5 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD65105.1 - 6.7e-05 21.9 0.2 0.036 12.9 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EMD65105.1 - 0.00017 21.5 0.8 0.00059 19.7 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD65105.1 - 0.0028 16.6 0.0 0.006 15.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMD65105.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD65105.1 - 0.047 12.3 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EMD65105.1 - 0.058 13.4 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2616 PF11077.3 EMD65106.1 - 0.059 12.8 0.1 0.064 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) Ring_hydroxyl_A PF00848.14 EMD65109.1 - 4.8e-33 114.5 1.7 1.3e-32 113.1 1.2 1.8 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EMD65109.1 - 5.7e-18 64.2 0.0 1.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 EMD65110.1 - 1e-66 225.2 0.1 1.7e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EMD65110.1 - 2.1e-52 177.5 0.0 4.3e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Lactamase_B PF00753.22 EMD65110.1 - 3.7e-23 82.1 0.5 7e-23 81.2 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily GCV_T_C PF08669.6 EMD65110.1 - 8.3e-16 57.7 0.0 1.8e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.22 EMD65110.1 - 2.4e-06 27.8 0.2 0.0043 17.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 EMD65110.1 - 2.1e-05 24.4 0.0 0.0036 17.1 0.0 3.4 3 0 0 3 3 3 1 Sarcosine oxidase, gamma subunit family Pyr_redox_3 PF13738.1 EMD65110.1 - 0.0001 22.4 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD65110.1 - 0.00012 20.8 0.3 0.0013 17.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EMD65110.1 - 0.00047 19.9 0.2 0.26 11.0 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lactamase_B_2 PF12706.2 EMD65110.1 - 0.0012 18.4 0.1 0.0031 17.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ThiF PF00899.16 EMD65110.1 - 0.002 17.9 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EMD65110.1 - 0.002 18.1 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.9 EMD65110.1 - 0.0028 17.5 0.1 0.066 13.0 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD65110.1 - 0.0086 15.1 0.5 0.094 11.7 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EMD65110.1 - 0.017 15.2 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EMD65110.1 - 0.019 14.9 0.0 0.066 13.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD65110.1 - 0.05 12.4 0.1 0.13 11.0 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain IF-2B PF01008.12 EMD65111.1 - 3.9e-74 249.1 0.1 4.9e-74 248.8 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TrkA_C PF02080.16 EMD65111.1 - 0.022 14.3 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-C domain RCC1_2 PF13540.1 EMD65112.1 - 3.7e-11 42.3 18.6 6.3e-06 25.6 0.2 6.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EMD65112.1 - 1.5e-07 31.5 4.1 0.0013 18.9 0.0 4.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EMD65112.1 - 4.9e-05 22.9 0.5 9.7e-05 22.0 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD65112.1 - 0.0017 17.9 1.8 0.002 17.7 0.3 1.8 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EMD65112.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain HET PF06985.6 EMD65113.1 - 5.7e-13 49.2 0.1 1.2e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UQ_con PF00179.21 EMD65116.1 - 6.8e-39 132.5 0.0 7.8e-39 132.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD65116.1 - 0.028 14.1 0.0 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B RNase_PH PF01138.16 EMD65117.1 - 1.1e-11 45.1 0.1 1.8e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Sulfate_tra_GLY PF13792.1 EMD65117.1 - 0.046 13.3 0.2 0.084 12.5 0.2 1.4 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif DUF1049 PF06305.6 EMD65118.1 - 0.084 12.3 5.5 2.2 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) A_deaminase PF00962.17 EMD65119.1 - 8.7e-40 136.6 0.0 2.4e-39 135.1 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase GATase_4 PF13230.1 EMD65120.1 - 5.3e-17 61.3 0.0 3.3e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMD65120.1 - 2.1e-09 37.4 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMD65120.1 - 1.8e-07 30.2 0.0 9e-06 24.6 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Arm PF00514.18 EMD65121.1 - 7.9e-97 314.1 12.7 1.1e-13 50.4 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMD65121.1 - 2.3e-27 95.0 2.9 2.6e-10 40.4 0.1 5.8 1 1 6 7 7 7 7 HEAT repeats IBB PF01749.15 EMD65121.1 - 5.2e-22 77.8 1.9 9.2e-22 77.0 1.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EMD65121.1 - 9.2e-21 72.0 1.3 6.8e-06 25.7 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EMD65121.1 - 9.6e-21 73.6 11.2 5.9e-09 36.1 0.0 6.2 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EMD65121.1 - 1.2e-11 44.2 0.0 0.017 14.2 0.0 4.2 2 1 2 4 4 4 4 Armadillo-like Adaptin_N PF01602.15 EMD65121.1 - 1.2e-06 27.1 0.0 4.4e-05 22.0 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EMD65121.1 - 6.1e-05 22.9 0.0 0.9 9.4 0.0 4.6 3 1 0 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EMD65121.1 - 0.003 15.9 0.1 0.24 9.5 0.0 2.7 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EMD65121.1 - 0.0038 17.5 6.5 0.55 10.8 0.2 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EMD65121.1 - 0.0089 15.9 4.9 1.6 8.7 0.0 4.7 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.12 EMD65121.1 - 0.012 15.2 0.0 19 4.9 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 EMD65121.1 - 0.17 10.8 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Mo25-like SURF6 PF04935.7 EMD65121.1 - 1.4 8.1 6.2 2.1 7.5 4.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 EMD65122.1 - 4.6e-06 26.6 0.0 2.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF2681 PF10883.3 EMD65122.1 - 0.41 10.8 3.9 1 9.6 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) U1snRNP70_N PF12220.3 EMD65122.1 - 0.53 10.6 8.1 1.2 9.4 5.6 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EMP24_GP25L PF01105.19 EMD65122.1 - 0.86 9.2 4.3 2.5 7.7 3.0 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF543 PF04418.7 EMD65124.1 - 2.2e-27 94.7 0.0 2.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 EMD65125.1 - 7.7e-44 149.9 0.0 3.9e-43 147.6 0.0 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family PHD PF00628.24 EMD65126.1 - 2.1e-11 43.2 6.9 2.4e-11 43.1 4.7 1.0 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMD65126.1 - 0.00041 19.6 0.8 0.00061 19.0 0.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EMD65126.1 - 0.24 11.4 1.7 0.4 10.7 1.2 1.5 1 1 0 1 1 1 0 RING-like domain Fe-ADH PF00465.14 EMD65128.1 - 2.2e-57 194.3 0.0 3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMD65128.1 - 3.7e-10 39.5 0.2 8.3e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase GCV_H PF01597.14 EMD65129.1 - 2.7e-35 120.6 1.4 3.4e-35 120.3 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EMD65129.1 - 0.037 13.6 0.6 0.084 12.5 0.4 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.12 EMD65130.1 - 8.7e-10 38.3 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF2422 PF10337.4 EMD65134.1 - 2e-106 356.5 17.7 6.9e-104 348.1 0.7 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EMD65134.1 - 8.2e-13 48.3 19.6 8.2e-13 48.3 13.6 2.8 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EMD65134.1 - 8e-12 45.2 0.0 4.5e-10 39.5 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EMD65134.1 - 1.2 9.0 24.3 0.11 12.4 6.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF939) DUF2273 PF10031.4 EMD65134.1 - 9.4 5.9 16.4 0.71 9.5 4.3 3.5 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) Utp8 PF10395.4 EMD65135.1 - 0.23 9.7 4.2 0.32 9.2 0.0 2.4 3 0 0 3 3 3 0 Utp8 family AAA PF00004.24 EMD65136.1 - 8.2e-08 32.5 0.0 7.1e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EMD65136.1 - 2.1e-07 29.9 0.1 2.8e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EMD65136.1 - 3.2e-05 24.7 0.0 7.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD65136.1 - 0.00063 19.7 0.5 0.0042 17.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD65136.1 - 0.005 16.9 0.1 0.056 13.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EMD65136.1 - 0.019 14.6 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EMD65136.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EMD65136.1 - 0.045 14.0 0.0 0.24 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMD65136.1 - 0.06 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMD65136.1 - 0.075 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EMD65136.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 EMD65136.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UCH PF00443.24 EMD65137.1 - 2e-40 138.6 0.1 2.9e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD65137.1 - 1.7e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 EMD65138.1 - 1.9e-24 86.4 10.2 2.9e-24 85.8 7.1 1.3 1 0 0 1 1 1 1 Alb1 DUF4211 PF13926.1 EMD65139.1 - 1.6e-34 118.5 1.7 1.6e-34 118.5 1.2 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4211) PalH PF08733.5 EMD65140.1 - 2.9e-98 328.9 0.0 4.1e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 PalH/RIM21 PX PF00787.19 EMD65141.1 - 2.6e-16 59.4 0.1 7.8e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 PX domain V-SNARE_C PF12352.3 EMD65141.1 - 0.0026 17.7 0.1 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prefoldin_3 PF13758.1 EMD65141.1 - 0.12 12.1 2.7 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF3552 PF12072.3 EMD65141.1 - 0.26 10.4 8.3 0.42 9.8 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ribosomal_S14 PF00253.16 EMD65142.1 - 7.3e-19 66.9 2.7 9.1e-19 66.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EMD65142.1 - 0.15 11.8 0.3 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) STAG PF08514.6 EMD65143.1 - 4.1e-26 91.0 0.6 2.3e-25 88.6 0.0 2.5 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EMD65143.1 - 5e-08 33.1 0.2 0.00016 21.8 0.0 4.1 4 1 1 5 5 5 2 HEAT repeats Cullin PF00888.17 EMD65144.1 - 8.1e-127 424.2 6.5 1e-126 423.9 4.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMD65144.1 - 8.7e-23 79.9 0.3 2.1e-22 78.6 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EMD65144.1 - 0.0081 16.0 0.1 0.025 14.4 0.1 1.9 1 0 0 1 1 1 1 HbrB-like Ribosomal_S22 PF08136.6 EMD65145.1 - 0.058 13.5 1.8 9.8 6.4 0.0 3.1 3 0 0 3 3 3 0 30S ribosomal protein subunit S22 family DUF4181 PF13789.1 EMD65146.1 - 0.077 12.9 8.9 0.19 11.6 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) IncA PF04156.9 EMD65146.1 - 0.59 9.6 4.5 0.79 9.2 3.1 1.1 1 0 0 1 1 1 0 IncA protein DUF3092 PF11289.3 EMD65146.1 - 7.7 5.6 7.8 8.4 5.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Ribosomal_L32e PF01655.13 EMD65148.1 - 2.2e-48 162.8 1.1 4.5e-48 161.8 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 Cullin_binding PF03556.10 EMD65148.1 - 1e-31 109.4 7.1 1.7e-31 108.7 4.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EMD65149.1 - 3e-09 36.2 0.3 5.5e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Pol_alpha_B_N PF08418.5 EMD65150.1 - 4.5e-60 203.2 0.2 7e-60 202.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EMD65150.1 - 1.7e-35 122.2 0.0 2.4e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B LTV PF04180.9 EMD65150.1 - 0.035 13.6 0.1 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Low temperature viability protein CRAL_TRIO PF00650.15 EMD65151.1 - 2.6e-38 131.0 0.0 3.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD65151.1 - 3.3e-10 39.9 0.2 8.6e-10 38.6 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMD65151.1 - 5.5e-07 29.6 0.0 7.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HTH_8 PF02954.14 EMD65151.1 - 0.086 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Peptidase_C37 PF05416.7 EMD65152.1 - 0.003 15.9 5.3 0.0052 15.1 3.7 1.3 1 0 0 1 1 1 1 Southampton virus-type processing peptidase HTH_5 PF01022.15 EMD65153.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF3186 PF11382.3 EMD65153.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) LexA_DNA_bind PF01726.11 EMD65153.1 - 0.16 11.5 0.1 0.74 9.4 0.0 2.0 2 0 0 2 2 2 0 LexA DNA binding domain Dynamin_N PF00350.18 EMD65154.1 - 1.3e-41 142.1 0.0 2.3e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMD65154.1 - 4.7e-11 42.0 0.0 1.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EMD65154.1 - 0.00071 19.5 0.0 0.0026 17.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD65154.1 - 0.0043 17.5 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF2344 PF10105.4 EMD65154.1 - 0.035 13.5 1.3 4.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) AAA_16 PF13191.1 EMD65154.1 - 0.038 13.9 0.4 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 EMD65154.1 - 0.07 13.0 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3899 PF13038.1 EMD65154.1 - 0.24 11.5 0.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) UreD PF01774.12 EMD65155.1 - 1e-52 178.6 0.0 1.3e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Peptidase_S41 PF03572.13 EMD65156.1 - 3.8e-07 29.6 0.0 1.8e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S41 AAA_22 PF13401.1 EMD65157.1 - 5.6e-06 26.5 0.0 1.8e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD65157.1 - 5.9e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EMD65157.1 - 0.00024 21.9 0.0 0.00069 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD65157.1 - 0.00035 20.5 2.0 0.00085 19.3 0.2 2.5 3 1 0 3 3 2 1 AAA ATPase domain AAA PF00004.24 EMD65157.1 - 0.00041 20.5 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMD65157.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD65157.1 - 0.0023 17.6 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EMD65157.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EMD65157.1 - 0.0084 15.9 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD65157.1 - 0.068 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 EMD65157.1 - 0.13 11.7 0.0 0.63 9.5 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.9 EMD65157.1 - 0.13 11.2 0.5 2.8 6.8 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 EMD65157.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EMD65157.1 - 0.14 11.1 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EMD65157.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMD65157.1 - 0.2 11.3 0.0 0.73 9.5 0.0 1.9 2 0 0 2 2 2 0 NTPase ZZ PF00569.12 EMD65157.1 - 0.5 9.9 8.1 1.6 8.2 5.8 1.8 1 1 0 1 1 1 0 Zinc finger, ZZ type HET PF06985.6 EMD65158.1 - 7.1e-22 78.0 0.1 1.7e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Terpene_synth_C PF03936.11 EMD65160.1 - 5.4e-13 48.7 0.0 6.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2236 PF09995.4 EMD65161.1 - 9.2e-28 97.1 0.1 1.6e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Ribosomal_S28e PF01200.13 EMD65161.1 - 0.21 11.3 0.9 0.83 9.4 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein S28e Sec39 PF08314.6 EMD65161.1 - 0.21 9.4 0.2 0.29 8.9 0.1 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 B-block_TFIIIC PF04182.7 EMD65163.1 - 3e-16 59.0 0.0 8e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC AT_hook PF02178.14 EMD65163.1 - 8.1 6.4 12.1 9.2 6.3 1.5 3.2 2 0 0 2 2 2 0 AT hook motif Acetyltransf_1 PF00583.19 EMD65165.1 - 1.8e-08 34.2 0.0 3.7e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD65165.1 - 2e-06 27.9 0.1 3.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD65165.1 - 4.2e-06 26.6 0.0 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD65165.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD65165.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EMD65165.1 - 0.043 13.6 0.1 0.1 12.4 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain CENP-B_dimeris PF09026.5 EMD65167.1 - 4 7.7 7.4 3.8 7.8 1.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Las1 PF04031.8 EMD65168.1 - 5.5e-34 117.0 0.6 1.1e-33 116.0 0.4 1.5 1 0 0 1 1 1 1 Las1-like Mito_carr PF00153.22 EMD65169.1 - 9e-58 192.0 3.8 2.7e-20 71.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EMD65170.1 - 3.7e-17 61.4 3.8 2.3e-10 39.9 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMD65170.1 - 0.055 12.2 0.2 5.7 5.5 0.1 2.3 1 1 1 2 2 2 0 Nup133 N terminal like OHCU_decarbox PF09349.5 EMD65173.1 - 4.1e-41 140.9 0.1 4.7e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase polyprenyl_synt PF00348.12 EMD65176.1 - 2.7e-56 190.2 0.0 3.5e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Aldolase_2 PF10120.4 EMD65176.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative aldolase F-box-like_2 PF13013.1 EMD65177.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.5 1 1 0 1 1 1 1 F-box-like domain LZ_Tnp_IS66 PF13007.2 EMD65177.1 - 0.026 15.1 0.2 0.058 14.0 0.1 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain WD40 PF00400.27 EMD65178.1 - 3.3e-07 29.9 0.1 0.045 13.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Sec2p PF06428.6 EMD65180.1 - 8.4e-13 48.0 14.0 1.3e-10 41.0 7.1 2.2 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Laminin_I PF06008.9 EMD65180.1 - 0.0013 18.0 2.2 0.074 12.3 0.1 2.2 2 0 0 2 2 2 1 Laminin Domain I HSBP1 PF06825.7 EMD65180.1 - 0.0015 18.0 0.0 1.6 8.3 0.0 3.2 2 1 0 2 2 2 1 Heat shock factor binding protein 1 Tropomyosin PF00261.15 EMD65180.1 - 0.0037 16.3 1.8 0.0037 16.3 1.3 2.1 2 0 0 2 2 2 1 Tropomyosin ERM PF00769.14 EMD65180.1 - 0.0052 16.3 1.3 0.0052 16.3 0.9 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Mnd1 PF03962.10 EMD65180.1 - 0.0074 15.9 7.0 0.44 10.1 0.4 2.2 2 0 0 2 2 2 2 Mnd1 family SPX PF03105.14 EMD65180.1 - 0.015 15.1 0.5 0.035 13.8 0.3 1.6 1 1 0 1 1 1 0 SPX domain TBPIP PF07106.8 EMD65180.1 - 0.019 14.5 6.8 0.29 10.6 0.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TFIID-18kDa PF02269.11 EMD65180.1 - 0.024 14.4 2.5 0.065 13.0 1.7 1.8 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Spc7 PF08317.6 EMD65180.1 - 0.03 12.9 0.6 0.03 12.9 0.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 EMD65180.1 - 0.055 12.8 0.5 0.055 12.8 0.3 2.3 2 0 0 2 2 2 0 PspA/IM30 family HR1 PF02185.11 EMD65180.1 - 0.055 13.2 14.7 0.072 12.8 0.7 2.6 2 0 0 2 2 2 0 Hr1 repeat Tmemb_cc2 PF10267.4 EMD65180.1 - 0.062 11.8 5.6 0.21 10.1 0.0 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein BCAS2 PF05700.6 EMD65180.1 - 0.092 12.1 5.2 1.3 8.4 0.4 2.2 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3373 PF11853.3 EMD65180.1 - 0.11 10.9 1.5 0.82 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) PAT1 PF09770.4 EMD65180.1 - 0.12 10.6 4.1 0.14 10.3 2.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2800 PF10926.3 EMD65180.1 - 0.13 11.3 1.9 1.5 7.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) DUF3450 PF11932.3 EMD65180.1 - 0.13 11.5 8.8 0.4 9.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 EMD65180.1 - 0.16 12.4 0.2 0.16 12.4 0.1 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4391 PF14335.1 EMD65180.1 - 0.17 11.2 3.9 0.17 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) V_ATPase_I PF01496.14 EMD65180.1 - 0.19 9.5 4.7 0.79 7.4 1.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Acyl-CoA_ox_N PF14749.1 EMD65180.1 - 0.44 10.8 4.2 0.28 11.5 0.3 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal ORF6C PF10552.4 EMD65180.1 - 0.48 10.1 2.9 2.2 8.0 0.1 2.4 2 1 0 2 2 2 0 ORF6C domain ATG16 PF08614.6 EMD65180.1 - 0.54 10.0 12.9 1.1 9.0 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 EMD65180.1 - 0.7 9.5 6.8 2.5 7.7 0.8 3.0 2 1 0 2 2 2 0 Prefoldin subunit ADIP PF11559.3 EMD65180.1 - 0.81 9.5 18.7 3.2 7.6 1.3 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF848 PF05852.6 EMD65180.1 - 0.82 9.5 8.8 2.6 7.8 0.2 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.7 EMD65180.1 - 0.95 9.8 14.3 5.4 7.4 0.6 3.8 2 2 2 4 4 4 0 SlyX Jnk-SapK_ap_N PF09744.4 EMD65180.1 - 1.5 8.8 13.6 5.2 7.0 0.2 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Adaptin_binding PF10199.4 EMD65180.1 - 1.6 8.9 5.9 0.66 10.2 0.1 2.4 1 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Occludin_ELL PF07303.8 EMD65180.1 - 2.2 9.0 6.9 3.7 8.3 0.1 2.4 2 1 0 2 2 2 0 Occludin homology domain DUF607 PF04678.8 EMD65180.1 - 2.3 8.0 5.8 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 AAA_13 PF13166.1 EMD65180.1 - 2.4 6.5 8.3 2.1 6.6 0.3 2.0 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 EMD65180.1 - 2.7 8.1 8.1 8.8 6.4 0.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 EMD65180.1 - 2.7 7.8 13.4 2.4 7.9 0.8 3.1 2 1 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 EMD65180.1 - 3.1 7.2 7.1 0.37 10.2 0.2 2.4 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Lge1 PF11488.3 EMD65180.1 - 3.2 8.0 9.0 28 4.9 0.1 3.3 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Myosin_tail_1 PF01576.14 EMD65180.1 - 3.6 5.1 25.0 2.2 5.9 0.7 2.4 2 1 0 2 2 2 0 Myosin tail Fmp27_WPPW PF10359.4 EMD65180.1 - 3.9 5.7 9.3 3.7 5.8 0.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EMD65180.1 - 4.1 6.9 17.8 3.8 7.0 2.2 2.3 2 0 0 2 2 2 0 IncA protein DUF2730 PF10805.3 EMD65180.1 - 4.3 7.1 8.3 43 3.8 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) MCRS_N PF13325.1 EMD65180.1 - 8.1 5.9 8.4 68 2.8 0.0 3.0 2 1 1 3 3 3 0 N-terminal region of micro-spherule protein Atg14 PF10186.4 EMD65180.1 - 8.7 5.1 15.1 2 7.3 0.7 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EMD65180.1 - 8.8 6.0 13.3 0.75 9.5 0.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GMC_oxred_N PF00732.14 EMD65182.1 - 2.3e-57 194.4 0.0 8.1e-57 192.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD65182.1 - 6.4e-28 97.8 0.0 1.1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD65182.1 - 2.5e-10 39.8 0.0 0.00011 21.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD65182.1 - 9e-06 25.6 0.4 2.1e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD65182.1 - 5.1e-05 22.3 0.2 0.014 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EMD65182.1 - 0.00015 21.9 0.1 0.54 10.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD65182.1 - 0.00044 20.1 0.2 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD65182.1 - 0.013 14.4 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMD65182.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD65182.1 - 0.037 12.5 0.4 0.092 11.2 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EMD65182.1 - 0.054 12.5 0.3 0.1 11.6 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EMD65182.1 - 0.11 12.9 1.8 0.32 11.4 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD65182.1 - 0.21 10.2 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.19 EMD65183.1 - 5.7e-78 262.5 15.9 6.5e-78 262.3 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65183.1 - 9.8e-31 106.7 36.2 9.5e-30 103.4 10.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD65183.1 - 2.1e-07 29.6 19.0 0.00014 20.4 1.3 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EMD65183.1 - 6.3e-07 27.9 5.8 4.4e-05 21.8 0.1 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PalH PF08733.5 EMD65183.1 - 0.88 8.3 9.6 1.6 7.4 6.7 1.4 1 0 0 1 1 1 0 PalH/RIM21 MFS_1_like PF12832.2 EMD65183.1 - 9.8 6.0 10.9 0.63 9.8 0.0 3.1 4 0 0 4 4 4 0 MFS_1 like family Erv26 PF04148.8 EMD65185.1 - 3.2 7.0 8.8 5.8 6.2 6.1 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DUF3328 PF11807.3 EMD65186.1 - 2.8e-35 122.0 1.3 3.4e-35 121.7 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NETI PF14044.1 EMD65186.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 NETI protein DUF2574 PF10836.3 EMD65187.1 - 0.61 9.8 5.8 0.66 9.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2574) Med3 PF11593.3 EMD65187.1 - 6 6.0 8.0 9.4 5.3 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1749 PF08538.5 EMD65189.1 - 8e-79 264.6 0.0 1e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EMD65189.1 - 2.2e-11 44.0 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65189.1 - 4.3e-08 33.0 0.0 1.4e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD65189.1 - 0.0017 17.6 0.0 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMD65189.1 - 0.0078 15.7 0.0 0.06 12.8 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMD65189.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EMD65189.1 - 0.14 11.7 0.0 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase LMBR1 PF04791.11 EMD65190.1 - 0.026 13.1 1.1 0.028 13.0 0.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Sigma_reg_N PF13800.1 EMD65190.1 - 4 7.5 5.7 2.4 8.2 0.9 2.0 1 1 0 2 2 2 0 Sigma factor regulator N-terminal Apq12 PF12716.2 EMD65190.1 - 9.3 6.0 13.1 1 9.1 1.1 2.4 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis DUF1793 PF08760.6 EMD65191.1 - 1.8e-69 233.0 0.0 4.1e-69 231.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Pkinase PF00069.20 EMD65193.1 - 1.9e-50 171.4 0.0 2.4e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65193.1 - 1.1e-28 99.9 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase S_layer_C PF05124.7 EMD65193.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region Herpes_LMP1 PF05297.6 EMD65193.1 - 0.034 13.0 0.6 0.053 12.4 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Kinase-like PF14531.1 EMD65193.1 - 0.16 10.9 0.8 0.46 9.4 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Arm PF00514.18 EMD65194.1 - 1.6e-69 227.5 31.6 6.2e-13 48.0 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMD65194.1 - 3.8e-27 94.3 10.5 1.3e-05 25.4 0.0 7.7 4 2 2 7 7 7 6 HEAT repeats HEAT PF02985.17 EMD65194.1 - 5.6e-22 75.8 14.5 0.017 15.1 0.0 9.9 11 0 0 11 11 9 5 HEAT repeat HEAT_EZ PF13513.1 EMD65194.1 - 6.7e-17 61.4 15.0 0.0018 18.7 0.1 8.5 6 2 3 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 EMD65194.1 - 4e-13 48.5 7.6 2.2e-08 32.8 0.7 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EMD65194.1 - 3.4e-12 45.1 0.3 6.9e-12 44.1 0.2 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EMD65194.1 - 2.2e-10 40.0 7.8 0.0043 16.1 0.2 3.5 1 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EMD65194.1 - 1.5e-08 34.1 2.0 0.00042 19.5 0.1 3.6 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.2 EMD65194.1 - 0.00013 21.8 2.5 7.9 6.2 0.0 4.5 2 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 EMD65194.1 - 0.00078 19.3 0.5 0.93 9.4 0.0 4.3 1 1 5 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 EMD65194.1 - 0.03 14.7 10.2 8.3 7.1 0.6 6.5 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMD65194.1 - 0.059 13.7 0.0 7 7.1 0.0 3.4 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EMD65194.1 - 0.064 12.9 2.6 0.21 11.2 0.2 2.7 3 0 0 3 3 2 0 rRNA processing/ribosome biogenesis Vpu PF00558.14 EMD65194.1 - 0.12 11.9 3.0 0.1 12.1 0.6 2.0 2 0 0 2 2 2 0 Vpu protein DUF1981 PF09324.5 EMD65194.1 - 0.13 11.8 0.0 18 4.9 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) Atx10homo_assoc PF09759.4 EMD65194.1 - 0.73 9.5 4.4 4.6 7.0 0.1 3.8 3 2 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RNA_pol_Rpc4 PF05132.9 EMD65195.1 - 2.6e-28 98.6 0.0 2.6e-28 98.6 0.0 3.7 5 0 0 5 5 5 2 RNA polymerase III RPC4 HATPase_c PF02518.21 EMD65196.1 - 2.9e-22 78.4 0.0 5.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD65196.1 - 1.6e-18 66.7 0.1 3.8e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMD65196.1 - 2.3e-12 47.1 0.0 0.0035 17.7 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.5 EMD65196.1 - 2.9e-10 40.1 0.1 0.00053 20.0 0.0 4.0 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 EMD65196.1 - 1.7e-08 34.3 0.1 1.7e-08 34.3 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EMD65196.1 - 1.7e-07 31.2 0.5 0.0013 18.7 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS PF00989.19 EMD65196.1 - 3.5e-06 26.7 0.0 0.056 13.2 0.0 4.3 3 1 0 3 3 3 2 PAS fold GAF_2 PF13185.1 EMD65196.1 - 0.014 15.8 0.0 0.082 13.3 0.0 2.2 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.1 EMD65196.1 - 0.029 14.4 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 GAF domain Ribonuc_red_sm PF00268.16 EMD65197.1 - 1.4e-118 395.0 0.5 1.6e-118 394.7 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PRP38 PF03371.10 EMD65197.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 PRP38 family WD40 PF00400.27 EMD65198.1 - 1.1e-32 110.7 5.9 2.9e-10 39.6 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD65198.1 - 0.015 15.0 0.1 2 8.2 0.0 3.7 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region AAA_3 PF07726.6 EMD65199.1 - 0.00053 19.6 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NAD_kinase PF01513.16 EMD65200.1 - 6.6e-73 244.9 0.0 9.3e-73 244.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Amidohydro_1 PF01979.15 EMD65201.1 - 8.9e-13 48.5 0.2 8.4e-12 45.3 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD65201.1 - 4.7e-11 42.3 0.1 1.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD65201.1 - 0.00044 19.5 0.3 0.0025 17.1 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 EMD65201.1 - 0.099 11.9 0.1 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region Porphobil_deam PF01379.15 EMD65203.1 - 6e-74 247.5 0.0 8.6e-74 247.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMD65203.1 - 1.1e-17 63.8 1.9 3.3e-17 62.3 1.3 1.8 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L12 PF00542.14 EMD65203.1 - 0.96 9.5 7.6 2.2 8.3 5.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain MFS_1 PF07690.11 EMD65204.1 - 1e-29 103.3 26.1 1e-29 103.3 18.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PLAC8 PF04749.12 EMD65205.1 - 2.3e-23 82.7 11.5 3.4e-23 82.2 8.0 1.3 1 0 0 1 1 1 1 PLAC8 family MIP-T3 PF10243.4 EMD65206.1 - 8.5 4.7 46.1 10 4.4 31.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 EMD65206.1 - 8.5 4.8 31.2 10 4.6 21.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TIP120 PF08623.5 EMD65207.1 - 9e-63 210.8 3.6 2.1e-62 209.6 0.1 3.4 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EMD65207.1 - 8.9e-16 57.9 19.7 0.011 15.9 0.0 8.9 6 2 4 10 10 10 7 HEAT repeats HEAT PF02985.17 EMD65207.1 - 2.8e-07 30.0 17.1 2.2 8.5 0.1 10.4 12 0 0 12 12 12 2 HEAT repeat Adaptin_N PF01602.15 EMD65207.1 - 4.9e-07 28.4 3.0 1.5 7.0 0.2 6.2 4 3 0 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.1 EMD65207.1 - 1.6e-05 25.2 32.2 2.4 8.7 0.0 13.1 12 3 3 15 15 15 2 HEAT-like repeat Arm PF00514.18 EMD65207.1 - 0.02 14.6 7.1 9.6 6.1 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UME PF08064.8 EMD65207.1 - 0.034 14.0 0.3 24 4.9 0.1 3.6 3 0 0 3 3 3 0 UME (NUC010) domain DUF3384 PF11864.3 EMD65207.1 - 0.067 11.6 0.1 0.96 7.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) DUF3385 PF11865.3 EMD65207.1 - 0.078 12.8 1.9 21 5.0 0.0 4.8 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) MMS19_C PF12460.3 EMD65207.1 - 0.27 9.8 10.5 3.4 6.2 0.1 5.4 6 1 0 6 6 6 0 RNAPII transcription regulator C-terminal PAN_4 PF14295.1 EMD65208.1 - 0.057 13.1 0.7 0.46 10.2 0.1 2.6 2 0 0 2 2 2 0 PAN domain DUF2263 PF10021.4 EMD65209.1 - 3.7e-17 62.6 0.0 6.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PseudoU_synth_2 PF00849.17 EMD65210.1 - 2.9e-27 95.5 0.0 4.9e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EMD65210.1 - 0.0027 17.1 0.2 0.0059 16.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain 4HBT PF03061.17 EMD65211.1 - 1.8e-10 40.8 0.0 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EMD65211.1 - 6e-07 29.9 0.1 7.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EMD65211.1 - 0.00011 21.2 2.8 0.00033 19.6 1.6 1.8 1 1 1 2 2 2 1 Acyl-ACP thioesterase Epsilon_antitox PF08998.6 EMD65211.1 - 0.045 13.7 0.1 0.22 11.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial epsilon antitoxin TPR_12 PF13424.1 EMD65213.1 - 4.8e-08 32.8 5.1 0.0015 18.4 0.1 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMD65213.1 - 0.092 12.7 0.8 2.4e+02 1.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EMD65214.1 - 0.00071 19.7 9.0 0.1 13.0 0.7 2.8 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD65214.1 - 0.0045 17.2 8.0 0.25 11.7 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SET PF00856.23 EMD65215.1 - 2.4e-08 34.4 0.0 9.8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 SET domain GFA PF04828.9 EMD65216.1 - 5.2e-14 51.9 0.1 6.7e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EMD65216.1 - 0.077 12.7 0.1 0.077 12.7 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.1 EMD65216.1 - 6.4 6.1 10.4 0.42 9.8 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Apc13p PF05839.6 EMD65217.1 - 3.7e-32 110.1 0.3 4.6e-32 109.8 0.2 1.1 1 0 0 1 1 1 1 Apc13p protein zf-rbx1 PF12678.2 EMD65218.1 - 3.6e-08 33.4 2.5 7e-08 32.4 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMD65218.1 - 2.6e-07 30.3 11.5 2.4e-06 27.2 6.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMD65218.1 - 7.8e-05 22.2 11.1 0.00022 20.7 7.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD65218.1 - 0.00026 20.6 10.9 0.0012 18.4 5.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD65218.1 - 0.00032 20.6 12.3 0.00039 20.3 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD65218.1 - 0.0011 18.7 8.9 0.0011 18.7 6.2 2.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMD65218.1 - 0.01 15.5 13.0 0.044 13.5 9.0 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EMD65218.1 - 0.017 14.9 4.7 0.039 13.7 2.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger XPG_I PF00867.13 EMD65219.1 - 1.6e-23 82.5 0.0 3.7e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMD65219.1 - 7.1e-07 29.4 0.0 4e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 XPG N-terminal domain UIM PF02809.15 EMD65219.1 - 0.00015 21.0 5.6 0.00015 21.0 3.9 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif Zn_clus PF00172.13 EMD65220.1 - 1.8e-05 24.5 8.0 6.9e-05 22.6 5.6 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MelC1 PF06236.6 EMD65221.1 - 0.14 12.1 0.2 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 DUF2424 PF10340.4 EMD65222.1 - 2e-25 89.2 0.0 2.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMD65222.1 - 6.3e-24 84.7 0.0 8.4e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD65222.1 - 0.00032 20.6 0.5 0.00042 20.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3425 PF11905.3 EMD65223.1 - 1.8e-33 115.2 2.0 3.3e-33 114.4 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4349 PF14257.1 EMD65223.1 - 0.001 18.4 1.1 0.0017 17.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) bZIP_1 PF00170.16 EMD65223.1 - 0.0079 16.1 3.5 0.0079 16.1 2.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 EMD65223.1 - 9.5 6.5 8.5 2.4 8.5 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) AMP-binding PF00501.23 EMD65225.1 - 2.5e-43 148.0 0.0 3.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD65225.1 - 6.4e-05 23.8 0.0 0.00018 22.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PI-PLC-X PF00388.14 EMD65228.1 - 1.3e-45 154.3 0.0 2.3e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMD65228.1 - 2.5e-33 114.5 0.0 5.2e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EMD65228.1 - 0.066 13.0 0.9 0.31 10.9 0.2 2.5 3 1 0 3 3 3 0 C2 domain MFS_1 PF07690.11 EMD65229.1 - 1.7e-09 36.9 31.3 2e-09 36.6 14.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EMD65229.1 - 0.0015 18.0 3.8 0.0035 16.8 2.6 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 COX8 PF02285.10 EMD65229.1 - 4.4 6.9 6.8 0.56 9.7 0.3 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII 2OG-FeII_Oxy_2 PF13532.1 EMD65230.1 - 9.8e-25 87.5 0.0 1.6e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_18 PF00704.23 EMD65232.1 - 1.1e-53 182.8 0.2 3.3e-53 181.3 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EMD65233.1 - 7.3e-06 25.7 0.5 0.00018 21.3 0.0 2.9 3 0 0 3 3 3 1 LysM domain LysM PF01476.15 EMD65234.1 - 3.8e-05 23.4 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain PaO PF08417.7 EMD65235.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase Cyclase PF04199.8 EMD65236.1 - 2.4e-16 59.9 0.3 3.9e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Putative cyclase Cupin_1 PF00190.17 EMD65236.1 - 0.052 12.9 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF3006 PF11213.3 EMD65236.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF4449 PF14613.1 EMD65237.1 - 4.2e-68 228.4 6.2 4.2e-68 228.4 4.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) CorA PF01544.13 EMD65238.1 - 1.7e-12 47.0 0.1 4.8e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glu-tRNAGln PF02686.10 EMD65238.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit PMP22_Claudin PF00822.15 EMD65238.1 - 0.089 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family PH PF00169.24 EMD65239.1 - 3.4e-32 110.7 0.5 1.2e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMD65239.1 - 1.1e-11 45.0 4.9 1.3e-05 25.4 0.2 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EMD65239.1 - 1.1e-09 38.5 0.7 2.1e-05 24.6 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EMD65239.1 - 1.2e-05 25.2 0.3 6.3e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EMD65239.1 - 3.2e-05 23.7 0.7 0.00013 21.7 0.1 2.1 2 1 0 2 2 2 1 PH domain DUF2477 PF10631.4 EMD65239.1 - 0.01 16.0 2.3 2.8 8.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) CheF-arch PF04283.7 EMD65239.1 - 0.01 15.0 0.1 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Chemotaxis signal transduction system protein F from archaea GTP_EFTU PF00009.22 EMD65240.1 - 2.1e-53 180.5 0.0 4.6e-53 179.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMD65240.1 - 1.5e-15 56.8 0.0 3.8e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD65240.1 - 1.5e-09 37.8 0.0 8e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMD65240.1 - 2.7e-08 33.5 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EMD65240.1 - 0.0022 17.5 0.0 0.064 12.8 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EMD65240.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SET PF00856.23 EMD65240.1 - 0.079 13.2 1.4 0.12 12.6 0.0 2.0 3 0 0 3 3 3 0 SET domain XLF PF09302.6 EMD65240.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 XLF (XRCC4-like factor) Zn_clus PF00172.13 EMD65241.1 - 2.2e-07 30.6 11.6 3.6e-07 29.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EMD65241.1 - 1.3 9.2 7.9 3 8.0 1.3 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ras PF00071.17 EMD65242.1 - 7e-57 191.3 0.1 8.8e-57 191.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD65242.1 - 3.1e-19 69.6 0.0 4.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD65242.1 - 2.2e-12 46.5 0.0 2.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD65242.1 - 3e-07 30.4 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMD65242.1 - 4.6e-07 29.2 0.0 5.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD65242.1 - 7.1e-07 28.8 0.0 1.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EMD65242.1 - 0.00022 20.8 0.5 0.0069 15.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMD65242.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMD65242.1 - 0.0011 18.1 0.1 0.0023 17.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EMD65242.1 - 0.0036 16.7 0.1 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EMD65242.1 - 0.0048 16.5 0.2 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMD65242.1 - 0.0057 16.3 0.2 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase Septin PF00735.13 EMD65242.1 - 0.006 15.6 0.1 0.04 12.9 0.0 2.1 2 0 0 2 2 2 1 Septin SRPRB PF09439.5 EMD65242.1 - 0.0069 15.6 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EMD65242.1 - 0.007 15.8 0.0 0.026 13.9 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EMD65242.1 - 0.0076 15.7 0.2 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EMD65242.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD65242.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EMD65242.1 - 0.021 14.5 0.1 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMD65242.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 EMD65242.1 - 0.062 12.5 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 EMD65242.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF914 PF06027.7 EMD65243.1 - 3.2e-06 26.2 1.3 3.2e-06 26.2 0.9 2.3 3 0 0 3 3 3 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EMD65243.1 - 3.6e-06 27.1 2.4 3.6e-06 27.1 1.6 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD65243.1 - 1.7e-05 24.8 6.4 1.7e-05 24.8 4.4 2.9 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EMD65243.1 - 0.00014 21.5 4.1 0.00014 21.5 2.8 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EMD65243.1 - 0.00016 20.7 7.5 0.00016 20.7 5.2 1.5 2 0 0 2 2 2 1 UAA transporter family Nuc_sug_transp PF04142.10 EMD65243.1 - 0.038 13.1 0.2 0.038 13.1 0.2 1.8 2 0 0 2 2 2 0 Nucleotide-sugar transporter TruB_N PF01509.13 EMD65244.1 - 1.8e-45 154.7 0.0 4.6e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) NLBH PF05211.7 EMD65244.1 - 0.12 11.5 0.1 0.41 9.8 0.1 1.8 2 0 0 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DnaJ PF00226.26 EMD65245.1 - 1e-17 63.5 1.4 2.8e-17 62.1 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EMD65245.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mit_KHE1 PF10173.4 EMD65245.1 - 3.9 7.2 8.3 0.27 11.0 2.0 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related ATP-synt_B PF00430.13 EMD65245.1 - 6 6.6 9.5 14 5.5 6.6 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MARVEL PF01284.18 EMD65246.1 - 0.00036 20.3 3.3 0.0012 18.6 2.5 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.1 EMD65246.1 - 0.0049 16.8 1.9 0.048 13.6 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4231) DUF588 PF04535.7 EMD65246.1 - 0.037 13.5 1.6 0.11 12.0 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF588) DUF2975 PF11188.3 EMD65246.1 - 0.67 9.6 3.5 9 6.0 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Gemini_mov PF01708.11 EMD65246.1 - 6.8 6.3 6.0 49 3.5 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein APH PF01636.18 EMD65247.1 - 5.2e-12 46.0 0.0 2.6e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMD65247.1 - 0.00099 17.8 0.1 0.53 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) PgaD PF13994.1 EMD65249.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein DUF1680 PF07944.7 EMD65250.1 - 3.9e-135 451.0 0.8 4.4e-135 450.8 0.6 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_transf_28 PF03033.15 EMD65251.1 - 2e-23 82.6 0.2 8.5e-23 80.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMD65251.1 - 7.2e-07 28.1 0.0 1.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EMD65251.1 - 0.094 12.8 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 ATG C terminal domain Bac_rhamnosid PF05592.6 EMD65252.1 - 1.8e-24 85.8 0.0 4.1e-20 71.4 0.0 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Laminin_G_1 PF00054.18 EMD65252.1 - 0.02 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain DUF1080 PF06439.6 EMD65252.1 - 0.037 13.9 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) DUF2939 PF11159.3 EMD65252.1 - 0.065 13.4 0.2 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Zn_clus PF00172.13 EMD65253.1 - 9.2e-08 31.8 9.1 1.7e-07 31.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD65253.1 - 1.6e-07 30.2 0.1 2.3e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cad PF03596.8 EMD65254.1 - 8.5e-12 45.1 20.3 1.3e-06 28.2 2.4 2.6 1 1 1 2 2 2 2 Cadmium resistance transporter Phtf-FEM1B_bdg PF12129.3 EMD65254.1 - 0.26 10.6 3.8 0.31 10.3 1.7 1.7 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor S1FA PF04689.8 EMD65254.1 - 0.3 10.9 3.1 0.36 10.7 0.1 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA RVT_1 PF00078.22 EMD65256.1 - 2.6e-07 30.2 2.1 2.6e-07 30.1 1.4 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CHIPS PF11434.3 EMD65256.1 - 0.057 13.0 3.1 0.062 12.9 2.2 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Zn_clus PF00172.13 EMD65261.1 - 1.6e-09 37.5 5.9 2.5e-09 36.8 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD65261.1 - 1.4e-06 27.2 1.2 2e-06 26.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EMD65262.1 - 3e-35 121.7 4.3 4e-35 121.3 3.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.4 EMD65262.1 - 0.015 15.0 0.2 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Pkinase PF00069.20 EMD65263.1 - 2.9e-18 65.9 0.0 4.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65263.1 - 2.7e-07 29.9 0.0 4.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAN_4 PF14295.1 EMD65264.1 - 3.2e-15 55.5 8.6 5.1e-10 38.9 1.0 3.4 4 0 0 4 4 4 2 PAN domain PAN_1 PF00024.21 EMD65264.1 - 2.1e-12 46.5 5.4 1.9e-06 27.5 0.2 2.4 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.7 EMD65264.1 - 3.8e-08 32.8 4.5 0.0013 18.2 0.3 2.6 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.6 EMD65264.1 - 0.00054 19.7 14.8 0.023 14.5 0.8 2.8 3 0 0 3 3 3 2 PAN-like domain MANEC PF07502.9 EMD65264.1 - 0.049 13.6 0.3 0.049 13.6 0.2 3.1 2 1 0 2 2 2 0 MANEC domain Peptidase_C3G PF12381.3 EMD65264.1 - 0.063 12.5 0.4 0.089 12.0 0.3 1.1 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase WSC PF01822.14 EMD65264.1 - 0.11 12.4 11.5 0.15 11.9 1.9 2.7 2 0 0 2 2 2 0 WSC domain Lustrin_cystein PF14625.1 EMD65264.1 - 0.13 12.4 10.7 0.97 9.5 0.1 3.4 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain FAA_hydrolase PF01557.13 EMD65266.1 - 4.9e-61 205.9 0.0 1e-60 204.9 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 EMD65266.1 - 6.9e-30 104.6 0.1 9.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65266.1 - 1.3e-16 60.6 0.1 4.7e-16 58.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD65266.1 - 8.3e-16 58.2 0.0 3.7e-10 39.7 0.0 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EMD65266.1 - 2.9e-06 27.0 0.3 2.6e-05 23.9 0.1 2.1 1 1 1 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 EMD65266.1 - 3.9e-05 23.4 0.0 0.00018 21.2 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EMD65266.1 - 0.016 13.7 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF2305 PF10230.4 EMD65266.1 - 0.026 13.9 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EMD65266.1 - 0.034 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1057 PF06342.7 EMD65266.1 - 0.14 10.9 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Cyt-b5 PF00173.23 EMD65267.1 - 4.2e-06 26.4 0.0 5.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidohydro_5 PF13594.1 EMD65268.1 - 1.9e-07 30.7 0.0 5.5e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD65268.1 - 0.0083 15.3 3.1 0.069 12.3 0.3 2.6 1 1 2 3 3 3 2 Amidohydrolase family Fungal_trans PF04082.13 EMD65269.1 - 1.2e-13 50.5 4.4 2e-13 49.8 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-primase PF09329.6 EMD65270.1 - 0.55 9.8 6.5 1.5 8.4 0.4 2.8 2 1 0 2 2 2 0 Primase zinc finger ECH PF00378.15 EMD65272.1 - 5.1e-51 173.1 0.0 6.9e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMD65272.1 - 0.00025 20.8 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 LUC7 PF03194.10 EMD65273.1 - 0.0037 16.8 0.2 0.0051 16.3 0.2 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Myc-LZ PF02344.10 EMD65273.1 - 0.0085 15.6 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 Myc leucine zipper domain HALZ PF02183.13 EMD65273.1 - 0.017 14.8 0.1 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3544 PF12064.3 EMD65273.1 - 0.018 14.8 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) FlaC_arch PF05377.6 EMD65273.1 - 0.061 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EMD65273.1 - 0.16 11.4 3.4 0.11 12.0 0.5 1.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EMD65273.1 - 0.17 11.8 15.6 0.33 10.9 0.2 2.8 1 1 2 3 3 3 0 bZIP transcription factor DUF724 PF05266.9 EMD65273.1 - 0.22 11.1 5.2 0.4 10.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF904 PF06005.7 EMD65273.1 - 0.25 11.6 3.1 0.43 10.9 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EMD65273.1 - 0.84 9.5 14.8 2.5 8.0 0.4 3.2 1 1 2 3 3 3 0 Basic region leucine zipper UCH PF00443.24 EMD65274.1 - 6.4e-47 159.9 0.0 1.4e-46 158.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD65274.1 - 7.2e-19 68.3 0.0 1.4e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LRR_4 PF12799.2 EMD65274.1 - 0.62 9.7 1.8 0.66 9.6 0.3 1.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Lin-8 PF03353.10 EMD65274.1 - 5.2 6.2 10.1 13 4.9 7.0 1.7 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-C3HC4 PF00097.20 EMD65275.1 - 8.9e-08 31.6 6.0 1.5e-07 30.9 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD65275.1 - 4.8e-07 29.7 7.5 8e-07 28.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD65275.1 - 2e-06 27.5 5.4 3.6e-06 26.7 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD65275.1 - 2.6e-06 26.9 4.9 4.2e-06 26.3 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD65275.1 - 4.2e-06 26.5 3.8 1e-05 25.3 2.7 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMD65275.1 - 9.1e-06 25.3 5.0 1.9e-05 24.2 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD65275.1 - 0.0053 16.4 5.1 0.012 15.3 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 EMD65275.1 - 0.29 11.0 2.4 0.77 9.6 1.6 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain Methyltrn_RNA_3 PF02598.12 EMD65277.1 - 4e-63 213.4 0.0 6.4e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase Cutinase PF01083.17 EMD65281.1 - 3.6e-43 147.3 3.4 5e-43 146.9 2.4 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD65281.1 - 0.0016 17.9 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 EMD65281.1 - 0.04 13.3 0.1 0.087 12.2 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_9 PF10081.4 EMD65281.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family FAD_binding_3 PF01494.14 EMD65282.1 - 5e-22 78.4 0.0 7.6e-22 77.8 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD65282.1 - 8.7e-14 51.1 0.2 1.3e-07 30.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD65282.1 - 3.7e-08 32.6 0.6 5.6e-08 32.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD65282.1 - 3e-07 29.2 0.4 2.7e-06 26.1 0.3 2.0 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EMD65282.1 - 3.1e-06 27.1 1.3 9.3e-06 25.5 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMD65282.1 - 6.1e-06 25.5 0.3 8.2e-06 25.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD65282.1 - 7e-06 26.0 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD65282.1 - 8.2e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD65282.1 - 2.3e-05 23.4 0.1 3.3e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EMD65282.1 - 2.8e-05 24.4 0.2 0.0085 16.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD65282.1 - 0.00014 21.1 1.3 0.3 10.1 0.3 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EMD65282.1 - 0.00052 19.1 0.5 0.00078 18.6 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EMD65282.1 - 0.00074 18.2 2.3 0.083 11.5 0.4 2.2 1 1 1 2 2 2 2 Tryptophan halogenase SE PF08491.5 EMD65282.1 - 0.0022 16.8 0.0 0.0043 15.9 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EMD65282.1 - 0.0026 16.7 0.5 0.0062 15.4 0.3 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EMD65282.1 - 0.0057 16.3 0.1 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EMD65282.1 - 0.026 14.2 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Rossmann-like domain AlaDh_PNT_C PF01262.16 EMD65282.1 - 0.059 12.9 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 120_Rick_ant PF12574.3 EMD65282.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen vMSA PF00695.14 EMD65283.1 - 0.053 12.7 1.1 0.086 12.0 0.3 1.6 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DUF2076 PF09849.4 EMD65284.1 - 4.5e-09 36.7 8.1 5.1e-09 36.5 5.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EMD65284.1 - 0.00033 20.4 1.8 0.0039 17.0 1.7 2.0 1 1 1 2 2 2 2 CHCH domain DUF605 PF04652.11 EMD65284.1 - 4.5 6.5 9.1 5.5 6.2 6.3 1.1 1 0 0 1 1 1 0 Vta1 like DLH PF01738.13 EMD65285.1 - 3.3e-28 98.4 0.0 3.7e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMD65285.1 - 9.1e-08 31.9 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMD65285.1 - 0.027 13.9 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) NMT1 PF09084.6 EMD65285.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like Peptidase_S9 PF00326.16 EMD65285.1 - 0.16 11.1 0.1 1.6 7.9 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family LRR_4 PF12799.2 EMD65288.1 - 7e-17 60.6 6.5 2.2e-07 30.3 1.8 4.4 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD65288.1 - 2.5e-13 49.5 4.1 6e-09 35.5 2.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMD65288.1 - 2.4e-09 35.9 10.1 0.076 13.0 0.1 6.4 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EMD65288.1 - 0.00011 21.9 9.8 13 6.2 0.2 5.8 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 EMD65288.1 - 0.00062 19.5 13.4 8.6 7.0 0.0 5.7 6 0 0 6 6 6 3 Leucine rich repeat Metallophos PF00149.23 EMD65290.1 - 6.4e-45 153.0 0.2 7.7e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase REV PF00424.13 EMD65291.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Sec2p PF06428.6 EMD65292.1 - 2.8e-23 81.6 9.4 2.8e-23 81.6 6.5 2.9 3 0 0 3 3 3 2 GDP/GTP exchange factor Sec2p DUF445 PF04286.7 EMD65292.1 - 0.0046 16.5 4.6 0.0046 16.5 3.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Sas10_Utp3 PF04000.10 EMD65293.1 - 4.1e-14 52.5 0.8 4.1e-14 52.5 0.5 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2413 PF10310.4 EMD65293.1 - 3.9 6.1 22.6 5.8 5.6 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ApbA_C PF08546.6 EMD65294.1 - 6.3e-33 113.4 0.3 1e-32 112.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMD65294.1 - 2e-20 72.7 0.0 4e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fructosamin_kin PF03881.9 EMD65295.1 - 3.9e-75 252.4 0.0 4.7e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMD65295.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD65295.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Nucleoplasmin PF03066.10 EMD65296.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EMD65296.1 - 5.3 7.2 7.5 4.8 7.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAD_binding_7 PF03441.9 EMD65297.1 - 2.2e-73 246.8 1.7 3.2e-73 246.3 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMD65297.1 - 4.3e-42 143.6 0.3 1.4e-41 142.0 0.0 2.0 3 0 0 3 3 3 1 DNA photolyase Alk_phosphatase PF00245.15 EMD65298.1 - 4.7e-76 256.1 0.1 1.4e-75 254.5 0.1 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EMD65298.1 - 7.1e-07 28.8 0.1 1.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD65298.1 - 3.8e-05 23.0 0.2 0.00011 21.5 0.1 1.8 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EMD65298.1 - 0.012 14.0 0.2 0.019 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EMD65298.1 - 0.025 13.9 0.2 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.7 EMD65298.1 - 0.08 12.5 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 PglZ domain PSI PF01437.20 EMD65299.1 - 0.085 13.0 0.8 0.085 13.0 0.6 1.6 2 0 0 2 2 2 0 Plexin repeat Phosducin PF02114.11 EMD65302.1 - 7.5e-10 37.9 0.0 9.4e-10 37.6 0.0 1.2 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EMD65303.1 - 7.1e-09 35.4 13.9 1.2e-08 34.7 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor PGBA_C PF15437.1 EMD65303.1 - 0.0025 17.8 2.5 0.0025 17.8 1.7 1.8 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal bZIP_2 PF07716.10 EMD65303.1 - 0.0033 17.2 12.2 0.0043 16.8 7.7 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD65303.1 - 0.0077 16.5 11.7 0.012 15.8 8.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MIS13 PF08202.6 EMD65303.1 - 0.0079 15.3 0.8 0.011 14.8 0.6 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family ADIP PF11559.3 EMD65303.1 - 0.019 14.8 9.1 0.032 14.1 6.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PAP1 PF08601.5 EMD65303.1 - 0.021 14.4 0.1 0.021 14.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 FlaC_arch PF05377.6 EMD65303.1 - 0.03 14.1 0.4 0.05 13.5 0.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glutaredoxin2_C PF04399.8 EMD65303.1 - 0.16 11.5 2.3 0.25 10.9 1.6 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 EMD65303.1 - 0.21 11.1 4.8 0.34 10.4 3.3 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EMD65303.1 - 0.21 11.9 1.1 0.35 11.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DDHD PF02862.12 EMD65303.1 - 0.25 11.0 2.6 0.37 10.5 1.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF724 PF05266.9 EMD65303.1 - 0.36 10.4 4.2 0.67 9.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4551 PF15087.1 EMD65303.1 - 1.3 7.3 5.3 1.6 7.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sigma70_r4_2 PF08281.7 EMD65304.1 - 6.7e-05 22.2 0.1 8.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EMD65304.1 - 0.00019 20.9 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.11 EMD65304.1 - 0.0049 16.1 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.5 EMD65304.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 IclR helix-turn-helix domain MFS_1 PF07690.11 EMD65305.1 - 2.2e-32 112.1 52.1 8.2e-27 93.8 19.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD65305.1 - 2.3e-18 66.0 26.0 2e-17 62.9 18.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 EMD65305.1 - 0.11 12.1 0.8 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF1228 PF06779.9 EMD65305.1 - 0.56 10.2 8.4 0.17 11.9 0.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) WD40 PF00400.27 EMD65306.1 - 1.9e-29 100.4 7.2 3.5e-07 29.8 0.0 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD65306.1 - 1.2e-06 28.3 0.4 0.036 13.7 0.0 3.4 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EMD65306.1 - 4.4e-06 25.7 0.1 0.045 12.5 0.1 2.8 2 1 1 3 3 3 2 Coatomer WD associated region PD40 PF07676.7 EMD65306.1 - 0.046 13.4 2.2 5.9 6.6 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RWD PF05773.17 EMD65307.1 - 2.1e-05 24.3 0.0 6.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RWD domain FAD_binding_4 PF01565.18 EMD65308.1 - 9.5e-36 122.3 4.7 9.5e-36 122.3 3.3 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMD65308.1 - 3e-08 33.4 0.2 6.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD65308.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Rsm22 PF09243.5 EMD65309.1 - 1.2e-28 99.8 0.0 3.6e-20 72.1 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 EMD65309.1 - 0.15 12.6 0.7 0.58 10.7 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain PH PF00169.24 EMD65311.1 - 0.00018 21.6 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EMD65311.1 - 0.00054 20.1 0.0 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain SCO1-SenC PF02630.9 EMD65313.1 - 1.8e-59 200.2 0.0 3.1e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EMD65313.1 - 0.00026 20.6 0.0 0.00061 19.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EMD65313.1 - 0.0027 17.8 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMD65313.1 - 0.039 13.4 0.1 0.37 10.3 0.0 2.2 1 1 0 1 1 1 0 Redoxin DAZAP2 PF11029.3 EMD65315.1 - 0.11 13.0 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) DDE_3 PF13358.1 EMD65316.1 - 2.1e-05 24.3 1.4 3.3e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease dsDNA_bind PF01984.15 EMD65319.1 - 1.5e-34 118.1 14.8 2e-34 117.7 10.2 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CD99L2 PF12301.3 EMD65319.1 - 0.0022 17.7 0.8 0.049 13.3 0.2 2.1 2 0 0 2 2 2 1 CD99 antigen like protein 2 DUF4615 PF15393.1 EMD65319.1 - 0.033 14.4 1.3 0.046 13.9 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) GatB_Yqey PF02637.13 EMD65319.1 - 0.049 13.3 0.8 0.067 12.9 0.6 1.3 1 0 0 1 1 1 0 GatB domain ATP-synt_D PF01813.12 EMD65320.1 - 0.017 14.6 1.4 0.045 13.2 1.0 1.9 1 1 0 1 1 1 0 ATP synthase subunit D Pup PF05639.6 EMD65320.1 - 0.2 12.2 0.6 0.2 12.2 0.4 2.9 2 1 0 2 2 2 0 Pup-like protein GAGA_bind PF06217.7 EMD65320.1 - 2.6 7.9 7.3 3.6 7.4 5.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SURF1 PF02104.10 EMD65321.1 - 2.4e-57 194.1 0.0 3e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SNN_transmemb PF09049.5 EMD65321.1 - 2.1 8.1 4.3 3.9 7.2 3.0 1.4 1 0 0 1 1 1 0 Stannin transmembrane CMS1 PF14617.1 EMD65322.1 - 6e-72 241.7 2.5 6.9e-72 241.5 1.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMD65322.1 - 0.00089 18.7 0.2 0.0011 18.5 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase FoP_duplication PF13865.1 EMD65322.1 - 0.07 13.5 4.3 0.14 12.6 3.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ras PF00071.17 EMD65324.1 - 8.8e-54 181.2 0.0 1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD65324.1 - 3.9e-17 62.8 0.0 6.1e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD65324.1 - 1.3e-07 30.9 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD65324.1 - 0.0018 17.7 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UBX PF00789.15 EMD65325.1 - 7.1e-07 29.2 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain eIF-3c_N PF05470.7 EMD65325.1 - 0.34 8.9 4.1 0.44 8.5 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MIP-T3 PF10243.4 EMD65325.1 - 0.79 8.1 20.4 0.014 13.8 9.6 1.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 EMD65325.1 - 1.3 8.3 21.9 0.32 10.3 9.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mnd1 PF03962.10 EMD65325.1 - 2.3 7.8 7.6 3.6 7.2 5.3 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 EMD65325.1 - 2.5 7.0 7.3 3.6 6.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arb2 PF09757.4 EMD65326.1 - 4.3e-18 65.3 0.0 6.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EMD65327.1 - 7.9e-16 57.1 2.3 1.3e-15 56.5 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e VASP_tetra PF08776.6 EMD65328.1 - 0.0019 17.4 0.0 0.8 9.0 0.0 2.6 2 0 0 2 2 2 2 VASP tetramerisation domain DUF305 PF03713.8 EMD65328.1 - 0.059 13.2 0.5 0.17 11.7 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF305) Collagen PF01391.13 EMD65329.1 - 1.9e-21 75.3 86.4 6.9e-06 25.5 7.3 7.2 6 1 1 7 7 7 6 Collagen triple helix repeat (20 copies) EI24 PF07264.6 EMD65330.1 - 8e-06 25.4 7.9 2.3e-05 23.9 5.5 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2418 PF10332.4 EMD65330.1 - 7.5 6.9 6.3 19 5.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) AAA_12 PF13087.1 EMD65331.1 - 2.2e-08 33.7 0.2 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain F-box-like_2 PF13013.1 EMD65331.1 - 0.054 13.2 0.2 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 F-box-like domain DUF1870 PF08965.5 EMD65331.1 - 0.13 11.9 0.1 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) SIP1 PF04938.7 EMD65332.1 - 0.00014 21.3 0.1 0.63 9.3 0.0 3.3 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Cytochrom_C PF00034.16 EMD65332.1 - 0.097 13.5 0.6 0.91 10.4 0.0 2.7 2 0 0 2 2 2 0 Cytochrome c tRNA-synt_His PF13393.1 EMD65333.1 - 5.4e-47 160.3 0.0 6.8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMD65333.1 - 5.7e-20 71.5 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD65333.1 - 8e-14 51.3 0.1 1.8e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMD65333.1 - 2.3e-06 26.6 0.1 0.0027 16.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EMD65333.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs zf-DHHC PF01529.15 EMD65335.1 - 1.6e-36 125.3 4.9 3.5e-36 124.2 3.4 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase SET PF00856.23 EMD65336.1 - 5e-19 69.1 0.1 5e-19 69.1 0.1 3.2 3 1 0 3 3 3 1 SET domain Raptor_N PF14538.1 EMD65337.1 - 1.9e-66 222.6 0.0 3.6e-66 221.7 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EMD65337.1 - 5.3e-07 29.2 9.7 0.28 11.1 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMD65337.1 - 0.00027 20.6 0.2 0.071 12.8 0.0 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EMD65337.1 - 0.027 14.5 3.7 5.2 7.4 0.1 4.8 6 0 0 6 6 6 0 HEAT repeat DUF1546 PF07571.8 EMD65337.1 - 0.048 13.7 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Atx10homo_assoc PF09759.4 EMD65337.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain tRNA-synt_2 PF00152.15 EMD65338.1 - 4.8e-75 252.3 0.0 7.1e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMD65338.1 - 0.00015 21.5 0.1 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMD65338.1 - 0.018 14.2 0.1 1.4 8.0 0.1 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) HSP70 PF00012.15 EMD65340.1 - 2.2e-79 266.9 0.5 2.2e-79 266.9 0.3 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD65340.1 - 5e-08 31.9 0.1 7.5e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 EMD65340.1 - 0.0024 17.3 1.1 0.0049 16.4 0.8 1.5 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 EMD65340.1 - 0.024 13.7 1.1 0.05 12.7 0.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Pap_E4 PF02711.9 EMD65340.1 - 0.056 14.2 0.1 0.12 13.1 0.1 1.6 1 0 0 1 1 1 0 E4 protein PBP1_TM PF14812.1 EMD65340.1 - 1 9.6 6.0 2.1 8.6 4.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.2 EMD65341.1 - 0.00012 21.7 0.1 0.00039 20.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EMD65341.1 - 0.0011 18.6 0.1 0.02 14.6 0.1 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EMD65341.1 - 0.0073 15.9 2.4 0.2 11.2 0.3 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EMD65341.1 - 0.023 14.3 0.1 0.091 12.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain LRR_7 PF13504.1 EMD65341.1 - 1.7 9.2 6.0 66 4.3 0.2 5.1 4 1 1 5 5 5 0 Leucine rich repeat Lactonase PF10282.4 EMD65342.1 - 4.5e-65 219.9 0.2 5.6e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Hydrolase_6 PF13344.1 EMD65343.1 - 9.3e-24 83.2 0.0 9.9e-23 79.9 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD65343.1 - 9.8e-17 60.4 0.0 4.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMD65343.1 - 0.00065 20.1 0.0 2 8.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMD65343.1 - 0.034 14.3 0.1 2 8.5 0.1 3.1 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-3CxxC PF13695.1 EMD65344.1 - 1.2e-26 92.8 1.4 1.2e-26 92.8 1.0 2.3 2 0 0 2 2 2 1 Zinc-binding domain zf-C2H2_jaz PF12171.3 EMD65344.1 - 6.4e-12 45.2 3.7 4.1e-05 23.5 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD65344.1 - 0.0008 19.5 2.4 0.066 13.4 0.5 4.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMD65344.1 - 0.013 15.5 5.2 1.9 8.6 1.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMD65344.1 - 0.16 12.3 6.7 4.3 7.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger 4HBT PF03061.17 EMD65347.1 - 7.3e-09 35.6 0.1 1.4e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily Vps5 PF09325.5 EMD65348.1 - 3.1e-87 291.7 6.2 4.9e-87 291.0 4.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMD65348.1 - 4.5e-25 87.6 0.0 1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 EMD65348.1 - 0.046 12.6 5.8 0.11 11.3 4.0 1.6 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EMD65348.1 - 0.12 11.8 5.0 0.18 11.2 3.5 1.3 1 0 0 1 1 1 0 BAR domain Glyco_hydro_43 PF04616.9 EMD65349.1 - 5.7e-104 347.2 3.5 6e-104 347.1 0.8 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMD65349.1 - 0.0044 16.4 0.4 0.012 15.0 0.3 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain CENP-F_leu_zip PF10473.4 EMD65350.1 - 0.0058 16.4 3.2 0.0058 16.4 2.2 3.4 2 2 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Suppressor_APC PF11414.3 EMD65350.1 - 0.52 10.1 6.7 5.4 6.8 0.1 3.6 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein His_Phos_2 PF00328.17 EMD65351.1 - 9.2e-22 77.8 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAD_binding_8 PF13450.1 EMD65352.1 - 1.2e-12 47.6 0.1 3.7e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMD65352.1 - 6e-11 42.0 0.0 1.2e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMD65352.1 - 1.1e-09 37.6 1.5 2.2e-08 33.3 0.3 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD65352.1 - 4.4e-06 26.7 0.0 7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD65352.1 - 1.7e-05 23.8 4.1 0.00036 19.4 3.9 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EMD65352.1 - 2e-05 23.9 0.0 9.7e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD65352.1 - 0.00017 21.7 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD65352.1 - 0.00017 20.2 0.6 0.0011 17.5 0.9 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EMD65352.1 - 0.00026 20.1 0.4 0.00073 18.6 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EMD65352.1 - 0.00026 21.3 3.8 0.00066 20.0 1.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMD65352.1 - 0.00053 19.1 0.2 0.026 13.6 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EMD65352.1 - 0.00084 18.7 0.4 0.0016 17.9 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EMD65352.1 - 0.0027 16.8 1.1 0.0046 16.0 0.7 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 EMD65352.1 - 0.0036 17.5 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMD65352.1 - 0.0056 16.4 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GDI PF00996.13 EMD65352.1 - 0.011 14.0 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_Gly3P_dh_N PF01210.18 EMD65352.1 - 0.011 15.4 0.2 0.036 13.7 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EMD65352.1 - 0.021 13.7 1.4 0.035 13.0 1.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMD65352.1 - 0.026 14.1 1.7 0.048 13.3 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMD65352.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_26 PF13659.1 EMD65352.1 - 0.033 14.2 0.0 0.09 12.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 EMD65352.1 - 0.042 13.6 0.7 0.096 12.5 0.5 1.5 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.1 EMD65352.1 - 0.043 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Methyltransf_18 PF12847.2 EMD65352.1 - 0.057 13.9 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GIDA PF01134.17 EMD65352.1 - 0.11 11.3 2.6 0.17 10.7 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.12 EMD65352.1 - 0.17 12.3 0.4 0.97 9.9 0.3 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.9 EMD65352.1 - 0.38 9.3 1.7 0.56 8.7 1.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Bac_rhodopsin PF01036.13 EMD65353.1 - 4.2e-57 193.0 14.8 4.9e-57 192.7 10.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 EMD65353.1 - 0.81 9.0 9.4 3.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RPE65 PF03055.10 EMD65354.1 - 2.9e-133 444.9 0.0 4.1e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SQS_PSY PF00494.14 EMD65355.1 - 6.6e-68 228.8 1.1 8.1e-68 228.5 0.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase GPI2 PF06432.6 EMD65356.1 - 3.2e-108 361.3 9.5 3.6e-108 361.1 6.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3382 PF11862.3 EMD65356.1 - 0.43 10.5 4.2 0.17 11.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) F-box-like_2 PF13013.1 EMD65357.1 - 0.11 12.2 0.7 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 F-box-like domain Annexin PF00191.15 EMD65358.1 - 4.9e-24 84.0 1.5 6.3e-06 26.0 0.0 4.6 4 0 0 4 4 4 4 Annexin Myb_DNA-binding PF00249.26 EMD65359.1 - 4.8e-09 36.1 0.0 4.5e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD65359.1 - 3.4e-06 27.0 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AhpC-TSA PF00578.16 EMD65360.1 - 9.2e-34 115.7 0.0 1.2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EMD65360.1 - 1.7e-16 59.5 0.1 3.1e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EMD65360.1 - 1.5e-15 56.9 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Acatn PF13000.2 EMD65361.1 - 4.7e-150 500.6 25.3 6.8e-77 259.2 6.9 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 EMD65362.1 - 9.3e-24 83.4 0.0 1.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF972 PF06156.8 EMD65362.1 - 0.022 15.0 0.7 0.045 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EMD65362.1 - 0.54 10.0 4.1 0.27 10.9 1.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_18 PF00704.23 EMD65365.1 - 1.1e-89 301.3 9.7 1.2e-89 301.1 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Radical_SAM PF04055.16 EMD65366.1 - 1.3e-12 48.1 0.0 2.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Adaptin_N PF01602.15 EMD65367.1 - 2.9e-112 375.6 0.0 3.9e-112 375.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EMD65367.1 - 1.8e-55 186.8 2.5 3.7e-55 185.8 1.8 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EMD65367.1 - 1.2e-15 57.4 7.9 0.00098 19.3 0.0 6.9 2 2 5 7 7 7 6 HEAT repeats HEAT_PBS PF03130.11 EMD65367.1 - 0.0085 16.4 0.7 8.4 7.1 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF3730 PF12530.3 EMD65367.1 - 0.066 13.1 2.5 0.87 9.4 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) HEAT PF02985.17 EMD65367.1 - 0.12 12.5 9.4 2.7 8.3 0.2 5.9 6 0 0 6 6 6 0 HEAT repeat PWI PF01480.12 EMD65367.1 - 0.27 11.3 1.4 0.85 9.7 0.0 2.5 3 0 0 3 3 3 0 PWI domain HEAT_EZ PF13513.1 EMD65367.1 - 6.6 7.3 10.2 0.27 11.7 0.2 3.7 5 0 0 5 5 5 0 HEAT-like repeat SET PF00856.23 EMD65368.1 - 8.6e-12 45.6 0.0 4.8e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 SET domain Coq4 PF05019.8 EMD65369.1 - 2.8e-94 314.1 0.0 3.4e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ATP-sulfurylase PF01747.12 EMD65370.1 - 1.7e-87 292.2 0.5 2.5e-87 291.7 0.0 1.5 2 0 0 2 2 2 1 ATP-sulfurylase APS_kinase PF01583.15 EMD65370.1 - 1.7e-55 186.9 0.0 3e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EMD65370.1 - 1.8e-54 183.5 0.0 2.9e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.14 EMD65371.1 - 2e-43 148.2 0.0 2.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Amidohydro_2 PF04909.9 EMD65372.1 - 4.8e-13 49.2 0.1 6.5e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase UPF0258 PF06789.7 EMD65372.1 - 0.0068 16.4 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0258) PfkB PF00294.19 EMD65373.1 - 4.3e-17 62.1 0.0 5.9e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TMEM51 PF15345.1 EMD65374.1 - 0.05 13.3 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 NAD_binding_1 PF00175.16 EMD65375.1 - 4.5e-07 30.4 0.0 0.026 15.0 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMD65375.1 - 0.00049 20.0 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EMD65375.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Abhydrolase_6 PF12697.2 EMD65376.1 - 2e-22 80.2 0.0 3.3e-22 79.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65376.1 - 1.1e-17 64.1 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD65376.1 - 1.7e-16 59.8 0.0 7e-16 57.8 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EMD65376.1 - 2.3e-09 37.1 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD65376.1 - 3.1e-05 23.2 0.0 0.052 12.7 0.0 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 EMD65376.1 - 5.4e-05 22.5 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF900 PF05990.7 EMD65376.1 - 0.0094 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 EMD65376.1 - 0.0098 14.8 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.8 EMD65376.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMD65376.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EMD65376.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Cation_efflux PF01545.16 EMD65377.1 - 5.1e-56 189.8 0.1 6.2e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EMD65377.1 - 0.0036 15.9 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 Cation transport protein UPF0147 PF03685.8 EMD65377.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) FGGY_C PF02782.11 EMD65378.1 - 7.5e-29 100.7 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMD65378.1 - 5.2e-19 68.5 0.0 2e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain CK2S PF15011.1 EMD65378.1 - 0.1 12.3 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate ATP-synt_DE_N PF02823.11 EMD65379.1 - 2.4e-20 72.0 0.1 4.2e-20 71.2 0.1 1.4 1 1 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DASH_Spc19 PF08287.6 EMD65380.1 - 3.5e-49 166.3 0.7 4.8e-49 165.8 0.5 1.2 1 0 0 1 1 1 1 Spc19 COG5 PF10392.4 EMD65380.1 - 0.52 10.2 3.3 8.3 6.3 0.1 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 FadA PF09403.5 EMD65380.1 - 0.68 9.9 4.0 7 6.6 0.7 2.3 2 1 0 2 2 2 0 Adhesion protein FadA ATP-synt_J PF04911.7 EMD65381.1 - 6.4e-26 89.5 0.7 7e-26 89.4 0.5 1.0 1 0 0 1 1 1 1 ATP synthase j chain Pkinase PF00069.20 EMD65382.1 - 1.4e-38 132.5 0.0 1.7e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65382.1 - 7.5e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD65382.1 - 1.5e-05 24.8 0.0 0.0016 18.2 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMD65382.1 - 0.05 12.3 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1923 PF09083.5 EMD65382.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) HLH PF00010.21 EMD65383.1 - 5.6e-15 54.7 0.6 1.3e-14 53.5 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EMD65383.1 - 0.0071 15.9 0.6 0.014 14.9 0.4 1.4 1 0 0 1 1 1 1 IncA protein DUF904 PF06005.7 EMD65383.1 - 0.15 12.3 1.6 0.42 10.9 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Bap31 PF05529.7 EMD65383.1 - 1.2 8.5 4.9 2.3 7.6 3.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like G-gamma PF00631.17 EMD65384.1 - 2.5e-21 75.1 0.1 3e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 EMD65384.1 - 0.15 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PCI PF01399.22 EMD65385.1 - 6.7e-09 36.0 2.2 4.6e-08 33.3 0.0 3.2 3 0 0 3 3 3 1 PCI domain PX PF00787.19 EMD65386.1 - 2.4e-26 91.7 0.0 2.8e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EMD65386.1 - 0.051 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus SSF PF00474.12 EMD65387.1 - 3.9e-06 25.7 28.6 5.2e-05 22.0 19.8 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family Cu-oxidase_2 PF07731.9 EMD65389.1 - 6e-24 84.1 1.8 1e-21 76.9 1.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMD65389.1 - 4.3e-21 74.8 0.0 1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EMD65389.1 - 0.00016 21.6 0.0 0.0031 17.4 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase CDP-OH_P_transf PF01066.16 EMD65390.1 - 2.3e-16 59.9 3.2 2.3e-16 59.9 2.2 2.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 EMD65391.1 - 1.7e-38 130.7 0.2 3.3e-27 94.4 0.0 2.6 2 0 0 2 2 2 2 NIPSNAP RhoGAP PF00620.22 EMD65392.1 - 1.6e-49 167.3 0.0 3.2e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EMD65392.1 - 5.2e-13 48.9 0.8 1.1e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Serpin PF00079.15 EMD65392.1 - 0.11 11.5 1.8 9.7 5.2 0.0 2.3 2 0 0 2 2 2 0 Serpin (serine protease inhibitor) Pyridox_oxidase PF01243.15 EMD65393.1 - 1.1e-11 44.5 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HMG_box PF00505.14 EMD65394.1 - 7.5e-24 83.7 1.4 1e-23 83.3 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD65394.1 - 5.1e-09 36.3 0.3 1.6e-08 34.8 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain Glyco_hydro_3 PF00933.16 EMD65395.1 - 2.3e-91 305.8 0.0 3.2e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD65395.1 - 4.6e-54 183.3 0.4 1.2e-52 178.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD65395.1 - 2.9e-24 84.7 0.1 5.6e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AMP-binding PF00501.23 EMD65397.1 - 1.3e-69 234.6 0.0 1.8e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD65397.1 - 3.6e-14 53.4 0.1 6.5e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain XPG_N PF00752.12 EMD65398.1 - 1.3e-35 121.6 0.1 3.7e-35 120.2 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EMD65398.1 - 4.3e-25 87.5 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMD65398.1 - 0.00019 21.6 0.0 0.00019 21.6 0.0 2.5 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EMD65398.1 - 0.0032 17.5 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family UIM PF02809.15 EMD65398.1 - 0.0049 16.3 0.9 0.0049 16.3 0.6 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF3336 PF11815.3 EMD65399.1 - 9.2e-49 164.6 3.9 1.4e-48 164.0 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMD65399.1 - 2.1e-20 73.5 0.1 1.2e-19 71.0 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Peptidase_M22 PF00814.20 EMD65400.1 - 2.5e-48 164.9 0.2 1.3e-28 100.2 0.1 3.1 2 1 1 3 3 3 3 Glycoprotease family FGGY_C PF02782.11 EMD65400.1 - 0.092 12.3 0.3 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Adipokin_hormo PF06377.6 EMD65401.1 - 0.0024 17.9 0.2 2.8 8.1 0.0 3.2 3 0 0 3 3 3 2 Adipokinetic hormone Ribosomal_L30 PF00327.15 EMD65403.1 - 0.093 12.3 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e CTP_transf_2 PF01467.21 EMD65404.1 - 0.0005 20.1 1.5 0.0055 16.7 0.4 2.9 3 1 0 3 3 3 1 Cytidylyltransferase WD40 PF00400.27 EMD65405.1 - 2.3e-20 71.6 6.7 3.5e-08 33.0 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PAT1 PF09770.4 EMD65405.1 - 0.55 8.4 43.9 1.1 7.4 30.4 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EMD65405.1 - 8.7 3.8 19.7 12 3.4 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Raffinose_syn PF05691.7 EMD65406.1 - 7.3e-51 172.6 5.7 3.8e-45 153.7 0.3 2.4 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_1b PF00579.20 EMD65407.1 - 1.4e-70 237.7 0.0 1.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2269 PF10027.4 EMD65409.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF3099 PF11298.3 EMD65409.1 - 1 9.1 3.3 2.1 8.1 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF3487 PF11990.3 EMD65410.1 - 0.19 11.1 1.6 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) NMT PF01233.14 EMD65412.1 - 1.7e-76 255.3 0.6 4.1e-76 254.0 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EMD65412.1 - 3.9e-76 254.6 0.0 6.8e-76 253.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EMD65412.1 - 1.1e-07 31.7 0.1 3.1e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Dehydrin PF00257.14 EMD65412.1 - 0.0068 16.7 6.8 0.014 15.7 4.7 1.4 1 0 0 1 1 1 1 Dehydrin DUF427 PF04248.7 EMD65412.1 - 0.06 13.0 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Acetyltransf_7 PF13508.1 EMD65412.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_12 PF13424.1 EMD65414.1 - 0.017 15.0 0.0 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD65414.1 - 0.1 12.5 0.1 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF946 PF06101.6 EMD65415.1 - 6.8e-18 63.9 4.4 2.1e-17 62.3 3.1 1.6 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EMD65415.1 - 0.076 12.7 0.5 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Catalase PF00199.14 EMD65416.1 - 1.8e-62 211.2 0.5 2.3e-62 210.9 0.3 1.0 1 0 0 1 1 1 1 Catalase NinE PF05322.6 EMD65416.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 NINE Protein ROK PF00480.15 EMD65416.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 ROK family Dicty_CAR PF05462.6 EMD65419.1 - 1.5e-12 47.0 10.1 1.5e-12 47.0 7.0 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EMD65419.1 - 0.0077 15.8 11.7 0.015 14.9 8.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMD65419.1 - 0.0097 15.6 0.6 0.0097 15.6 0.4 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term CS PF04969.11 EMD65420.1 - 3.2e-17 62.8 0.0 7.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 CS domain PET122 PF05476.6 EMD65420.1 - 0.1 11.8 0.3 0.79 8.9 0.1 2.0 2 0 0 2 2 2 0 PET122 Pinin_SDK_memA PF04696.8 EMD65420.1 - 0.34 10.5 4.4 0.16 11.5 0.6 1.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region ANTH PF07651.11 EMD65421.1 - 4.6e-63 212.5 0.1 6.1e-63 212.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMD65421.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain NPR2 PF06218.6 EMD65421.1 - 0.018 13.8 0.2 0.027 13.2 0.2 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 SET PF00856.23 EMD65422.1 - 6.6e-15 55.7 1.7 3e-14 53.6 0.2 2.8 2 1 0 2 2 2 1 SET domain DUF3950 PF13132.1 EMD65422.1 - 0.067 12.7 0.5 0.16 11.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) DAHP_synth_2 PF01474.11 EMD65424.1 - 1.6e-195 649.6 0.0 1.8e-195 649.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Adhesin_P1 PF03257.8 EMD65424.1 - 0.056 13.7 0.3 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Mycoplasma adhesin P1 DUF566 PF04484.7 EMD65425.1 - 3.2 7.1 5.8 3.4 7.1 4.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Zn_clus PF00172.13 EMD65427.1 - 2.1e-07 30.7 7.9 5.3e-07 29.4 5.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD65427.1 - 0.24 10.2 1.9 0.42 9.4 1.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain BTB PF00651.26 EMD65428.1 - 1.9e-13 50.3 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Nucleoporin_FG PF13634.1 EMD65428.1 - 0.00075 19.7 10.0 0.0013 18.9 7.0 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region DUF1989 PF09347.5 EMD65429.1 - 5.3e-30 104.0 0.0 2.8e-20 72.4 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF1989) PSDC PF12588.3 EMD65431.1 - 1e-53 180.7 0.0 1.7e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EMD65431.1 - 6.8e-33 113.6 0.0 1.5e-32 112.5 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Peptidase_M20 PF01546.23 EMD65432.1 - 1.5e-20 73.4 0.0 2.3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD65432.1 - 2.7e-13 49.6 0.1 6.5e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Complex1_LYR_1 PF13232.1 EMD65434.1 - 1.2e-20 73.4 3.3 1.7e-20 72.9 2.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMD65434.1 - 7.8e-20 70.4 3.0 1.4e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EMD65434.1 - 0.0057 17.1 0.8 0.0072 16.7 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PRP21_like_P PF12230.3 EMD65435.1 - 2.6e-53 180.8 10.9 9.2e-53 179.0 7.5 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EMD65435.1 - 4.7e-20 70.9 2.4 5.1e-12 45.2 0.4 2.4 2 0 0 2 2 2 2 Surp module zf-FCS PF06467.9 EMD65435.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C4H2 PF10146.4 EMD65435.1 - 1.5 8.7 17.4 53 3.7 12.1 2.6 1 1 0 1 1 1 0 Zinc finger-containing protein PMT PF02366.13 EMD65436.1 - 4.1e-78 262.1 14.6 4.1e-78 262.1 10.1 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMD65436.1 - 7.8e-56 188.6 0.0 1.4e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 MIR domain HTH_Tnp_Tc5 PF03221.11 EMD65439.1 - 2e-11 43.5 0.0 4.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD65439.1 - 5.8e-06 25.7 0.2 9.9e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD65439.1 - 0.0051 16.9 1.4 0.0082 16.2 0.4 1.7 1 1 1 2 2 2 1 Winged helix-turn helix DUF2500 PF10694.4 EMD65439.1 - 0.034 14.1 0.6 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Drf_GBD PF06371.8 EMD65439.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_28 PF13518.1 EMD65439.1 - 0.067 13.2 0.1 0.4 10.7 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD65439.1 - 0.085 12.5 0.3 0.6 9.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Aldolase_II PF00596.16 EMD65440.1 - 8.7e-34 116.7 0.4 1.6e-33 115.8 0.3 1.4 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RhgB_N PF09284.5 EMD65441.1 - 2.4e-101 338.2 3.3 3.3e-101 337.8 2.3 1.2 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EMD65441.1 - 6.9e-52 175.4 0.0 1.5e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMD65441.1 - 6.9e-16 58.1 2.4 6.9e-16 58.1 1.6 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMD65441.1 - 0.0077 16.2 1.6 0.0077 16.2 1.1 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain HTH_Tnp_Tc3_2 PF01498.13 EMD65442.1 - 2e-16 59.7 2.2 2.2e-16 59.6 0.5 1.8 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EMD65442.1 - 4.8e-08 33.1 0.3 1.3e-07 31.6 0.2 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.11 EMD65442.1 - 4.7e-06 25.8 0.4 0.072 12.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-70, region 4 HTH_32 PF13565.1 EMD65442.1 - 1.1e-05 26.0 1.0 1.4e-05 25.7 0.1 1.7 2 1 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EMD65442.1 - 4.9e-05 22.8 0.1 0.0097 15.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 EMD65442.1 - 0.00026 19.8 0.2 0.00035 19.4 0.1 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain Sigma70_r4_2 PF08281.7 EMD65442.1 - 0.00064 19.1 0.4 0.04 13.3 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_21 PF13276.1 EMD65442.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 HTH-like domain HTH_33 PF13592.1 EMD65442.1 - 0.0088 15.5 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.1 EMD65442.1 - 0.01 15.2 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding UB2H PF14814.1 EMD65442.1 - 0.012 15.2 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 0 Bifunctional transglycosylase second domain CENP-B_N PF04218.8 EMD65442.1 - 0.036 13.4 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain UPF0183 PF03676.9 EMD65445.1 - 3.3e-32 111.5 0.0 9e-22 77.1 0.0 4.1 3 2 0 3 3 3 3 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.17 EMD65446.1 - 1.8e-160 534.8 0.0 2.4e-160 534.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMD65446.1 - 3e-22 78.8 0.3 3.9e-13 48.8 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMD65446.1 - 9.5e-19 67.6 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EMD65446.1 - 1.5e-05 24.5 5.7 3.5e-05 23.3 4.0 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EMD65446.1 - 0.0093 15.1 0.0 0.83 8.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PDEase_I PF00233.14 EMD65447.1 - 3.3e-45 154.6 0.0 3.6e-42 144.7 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF1688 PF07958.6 EMD65449.1 - 2.1e-166 553.6 0.0 2.4e-166 553.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 EMD65449.1 - 0.00015 21.1 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) DUF1183 PF06682.7 EMD65450.1 - 0.0051 16.4 0.9 0.015 14.9 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) Herpes_gE PF02480.11 EMD65450.1 - 0.018 13.3 0.0 0.029 12.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Vpu PF00558.14 EMD65450.1 - 0.079 12.5 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Vpu protein SKG6 PF08693.5 EMD65451.1 - 1.4e-05 24.2 2.2 2.6e-05 23.4 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.3 EMD65451.1 - 0.0011 19.5 1.2 0.0036 17.8 0.7 1.8 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1191 PF06697.7 EMD65451.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) TMEM51 PF15345.1 EMD65451.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.1 EMD65451.1 - 0.0021 18.3 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Phage_Coat_B PF05356.6 EMD65451.1 - 0.0028 17.2 0.0 0.0076 15.9 0.0 1.8 2 0 0 2 2 2 1 Phage Coat protein B PDGLE PF13190.1 EMD65451.1 - 0.0032 17.1 0.1 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 PDGLE domain Herpes_gE PF02480.11 EMD65451.1 - 0.0039 15.5 0.0 0.0065 14.7 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Podoplanin PF05808.6 EMD65451.1 - 0.0087 15.6 0.8 0.035 13.6 0.2 2.0 2 0 0 2 2 2 1 Podoplanin DUF4064 PF13273.1 EMD65451.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3827 PF12877.2 EMD65451.1 - 0.013 13.6 0.0 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Adeno_E3_CR2 PF02439.10 EMD65451.1 - 0.013 14.9 1.0 0.024 14.1 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 EMD65451.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 EMD65451.1 - 0.029 14.4 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YadA_anchor PF03895.10 EMD65451.1 - 0.037 14.0 0.5 0.092 12.7 0.4 1.6 1 0 0 1 1 1 0 YadA-like C-terminal region Syndecan PF01034.15 EMD65451.1 - 0.047 13.3 0.7 0.097 12.3 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4366 PF14283.1 EMD65451.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Protocadherin PF08374.6 EMD65451.1 - 0.18 11.4 2.6 0.27 10.8 0.8 1.9 1 1 1 2 2 2 0 Protocadherin DUF3433 PF11915.3 EMD65453.1 - 1.5e-32 111.5 15.7 3.6e-22 78.3 1.6 3.6 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) TP_methylase PF00590.15 EMD65454.1 - 2.4e-47 161.3 0.4 3.8e-47 160.7 0.3 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EMD65454.1 - 4.6e-11 41.8 0.1 6.1e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EMD65454.1 - 3e-10 40.2 0.0 5.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EMD65454.1 - 2.3e-05 23.2 0.1 5.3e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rogdi_lz PF10259.4 EMD65455.1 - 8.4e-81 271.0 0.0 9.6e-81 270.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.7 EMD65456.1 - 8e-37 126.8 3.2 9.5e-37 126.6 2.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.8 EMD65456.1 - 0.0019 17.2 0.2 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Clc-like PF07062.7 EMD65456.1 - 0.0084 15.3 1.6 0.0084 15.3 1.1 1.5 2 0 0 2 2 2 1 Clc-like Amastin PF07344.6 EMD65456.1 - 0.21 11.1 8.5 0.51 9.9 4.6 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein Fig1 PF12351.3 EMD65456.1 - 3.1 7.6 10.8 2 8.2 5.3 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 EMD65456.1 - 3.9 7.1 20.8 0.28 10.8 10.2 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 EMD65456.1 - 4.8 7.3 7.4 12 6.1 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) SAICAR_synt PF01259.13 EMD65457.1 - 3.5e-87 291.6 0.0 4.3e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Alkyl_sulf_C PF14864.1 EMD65459.1 - 0.099 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Med12 PF09497.5 EMD65461.1 - 7.2e-25 86.7 0.2 1.6e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Nucleo_P87 PF07267.6 EMD65461.1 - 0.18 10.4 3.7 0.29 9.7 2.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UPF0139 PF03669.8 EMD65462.1 - 2.1e-05 23.9 0.1 2.8e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) CD20 PF04103.10 EMD65462.1 - 0.089 12.7 1.5 0.12 12.3 1.0 1.2 1 0 0 1 1 1 0 CD20-like family SUI1 PF01253.17 EMD65463.1 - 2.8e-29 100.7 5.4 3.8e-29 100.3 3.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EMD65463.1 - 0.21 11.7 0.6 0.75 9.9 0.1 1.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Tim44 PF04280.10 EMD65464.1 - 4e-05 23.6 0.0 0.0075 16.2 0.0 2.4 2 0 0 2 2 2 2 Tim44-like domain DUF2664 PF10867.3 EMD65464.1 - 4.8 7.8 5.8 4.1 8.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) Mito_carr PF00153.22 EMD65465.1 - 4.4e-76 250.6 2.7 1.3e-24 85.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CIA30 PF08547.7 EMD65466.1 - 5.1e-41 140.1 0.0 6.5e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 EMD65467.1 - 1.8e-30 104.6 10.0 2.9e-30 103.9 3.5 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.4 EMD65467.1 - 0.00012 21.4 0.1 0.00067 19.0 0.1 2.1 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EMD65467.1 - 0.02 15.5 4.7 43 5.1 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMD65467.1 - 0.072 12.9 0.0 9.7 6.2 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat COX6A PF02046.10 EMD65468.1 - 6.3e-40 135.7 3.7 6.7e-40 135.6 2.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EMD65469.1 - 1.1e-13 50.8 0.0 8.8e-13 47.9 0.0 2.5 2 2 1 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMD65469.1 - 4.2e-13 49.8 0.0 7.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EMD65469.1 - 0.00011 22.1 6.2 0.00027 20.7 4.3 1.8 1 1 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.5 EMD65469.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Myb_DNA-bind_6 PF13921.1 EMD65470.1 - 2.6e-06 27.4 1.0 0.00012 22.0 0.1 2.5 1 1 1 2 2 2 1 Myb-like DNA-binding domain PAT1 PF09770.4 EMD65470.1 - 0.0052 15.1 30.9 0.0049 15.1 21.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Myb_DNA-binding PF00249.26 EMD65470.1 - 0.016 15.2 0.3 0.077 13.0 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Nucleo_P87 PF07267.6 EMD65470.1 - 0.52 8.9 6.5 0.67 8.5 4.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ndc1_Nup PF09531.5 EMD65470.1 - 0.59 8.4 8.8 0.83 7.9 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4106 PF13388.1 EMD65470.1 - 0.86 8.4 24.1 1.5 7.6 16.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SIR2 PF02146.12 EMD65471.1 - 3.4e-28 98.5 0.0 6.4e-28 97.6 0.0 1.5 1 1 0 1 1 1 1 Sir2 family zf-C3HC4_3 PF13920.1 EMD65472.1 - 0.066 12.8 5.9 0.11 12.2 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EMD65472.1 - 0.82 9.4 12.0 1.3 8.7 8.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) adh_short PF00106.20 EMD65474.1 - 1.1e-17 64.3 0.1 3.4e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD65474.1 - 1.9e-08 34.3 0.2 1.7e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD65474.1 - 3.7e-05 23.4 0.2 0.00012 21.7 0.1 1.8 2 1 0 2 2 2 1 KR domain DFP PF04127.10 EMD65474.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Arylesterase PF01731.15 EMD65475.1 - 0.001 19.0 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Arylesterase FAD_binding_4 PF01565.18 EMD65476.1 - 1.4e-18 66.7 1.0 2.3e-18 65.9 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD65476.1 - 4.7e-13 48.8 0.8 2.1e-12 46.7 0.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EMD65476.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fungal_trans PF04082.13 EMD65478.1 - 2.7e-07 29.7 0.1 6.4e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65478.1 - 1.7e-05 24.6 10.8 2.6e-05 24.0 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCD14 PF08704.5 EMD65479.1 - 3e-11 43.3 0.0 6.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EMD65479.1 - 0.00011 21.8 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Metallophos PF00149.23 EMD65480.1 - 1.9e-11 43.7 3.5 3.6e-11 42.8 2.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD65480.1 - 3.3e-06 27.0 2.2 6.6e-06 26.0 1.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.14 EMD65480.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyoxal_oxid_N PF07250.6 EMD65481.1 - 4.3e-40 137.3 0.0 4.8e-39 133.8 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EMD65481.1 - 3.5e-23 81.5 0.9 6.8e-23 80.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EMD65481.1 - 1e-18 66.9 83.4 1e-08 35.0 13.4 3.8 3 0 0 3 3 3 3 Chitin recognition protein MFS_1 PF07690.11 EMD65483.1 - 3.9e-31 108.0 23.6 3.9e-31 108.0 16.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DFP PF04127.10 EMD65484.1 - 1.8e-14 53.7 0.0 7.8e-06 25.6 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein HET PF06985.6 EMD65485.1 - 2.1e-22 79.7 0.5 4.1e-22 78.8 0.1 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 EMD65486.1 - 2.8e-16 59.1 0.4 5.7e-16 58.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65486.1 - 4.9e-08 32.7 12.3 1.2e-07 31.4 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRCC PF10253.4 EMD65487.1 - 2.7 8.6 13.9 0.068 13.8 0.8 2.3 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Fungal_trans_2 PF11951.3 EMD65493.1 - 5.8e-11 41.6 0.7 1.2e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65493.1 - 2.2e-07 30.6 11.3 4.3e-07 29.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSrecog PF03531.9 EMD65494.1 - 2e-74 249.7 0.2 3.5e-73 245.6 0.2 2.3 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EMD65494.1 - 3.9e-29 100.4 0.1 1.5e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 EMD65494.1 - 2.1 6.2 7.6 2.8 5.8 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EMD65494.1 - 3.9 7.0 13.6 7.1 6.1 9.4 1.5 1 0 0 1 1 1 0 YL1 nuclear protein HET PF06985.6 EMD65495.1 - 4.3e-14 52.8 0.0 9.1e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RbcS PF12338.3 EMD65496.1 - 1.2 8.9 8.1 2.7 7.8 5.6 1.7 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit DNA_pol_B PF00136.16 EMD65497.1 - 8.7e-99 331.3 0.0 1.4e-98 330.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMD65497.1 - 6.3e-23 81.1 1.4 2.5e-13 49.5 0.1 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMD65497.1 - 1.5e-16 60.1 2.8 4.2e-16 58.6 1.9 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 EMD65498.1 - 8.9e-78 261.3 20.3 8.9e-78 261.3 14.1 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EMD65498.1 - 0.021 14.4 1.0 0.041 13.5 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle ANTH PF07651.11 EMD65499.1 - 9.3e-81 270.5 0.0 9.3e-81 270.5 0.0 3.1 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EMD65499.1 - 8.8e-63 210.7 7.6 8.8e-63 210.7 5.3 5.5 4 2 1 6 6 6 2 I/LWEQ domain ENTH PF01417.15 EMD65499.1 - 0.00019 21.3 0.0 0.0011 18.8 0.0 2.4 1 0 0 1 1 1 1 ENTH domain MFS_1 PF07690.11 EMD65500.1 - 8.6e-43 146.3 30.2 8.6e-43 146.3 20.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD65500.1 - 5.1e-07 28.2 5.8 8.7e-07 27.5 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AhpC-TSA PF00578.16 EMD65501.1 - 5.1e-33 113.3 0.0 6.9e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EMD65501.1 - 3.7e-12 45.6 0.1 6.8e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EMD65501.1 - 6.1e-12 45.3 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Kelch_3 PF13415.1 EMD65502.1 - 2.1e-19 69.1 2.5 3.9e-12 45.9 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EMD65502.1 - 2.1e-18 65.7 0.1 2.2e-07 30.5 0.0 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD65502.1 - 9.7e-11 41.3 5.8 0.00031 20.6 0.1 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EMD65502.1 - 1.7e-09 37.0 0.0 0.0012 18.3 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EMD65502.1 - 1.3e-07 31.0 0.8 0.00013 21.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 EMD65502.1 - 1.7e-06 27.9 2.7 0.25 11.5 0.0 5.3 3 1 1 4 4 4 2 Kelch motif BTB PF00651.26 EMD65502.1 - 0.0029 17.5 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain 7tm_1 PF00001.16 EMD65503.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 EMD65503.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) adh_short_C2 PF13561.1 EMD65504.1 - 3.2e-31 108.9 0.0 3.8e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD65504.1 - 8.5e-30 103.8 0.9 1.1e-29 103.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD65504.1 - 8.3e-18 64.6 0.4 1.1e-17 64.2 0.3 1.1 1 0 0 1 1 1 1 KR domain Alk_phosphatase PF00245.15 EMD65504.1 - 0.023 13.3 0.1 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase DUF3277 PF11681.3 EMD65504.1 - 0.033 13.6 0.1 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) NAD_binding_10 PF13460.1 EMD65504.1 - 0.042 13.8 0.2 0.76 9.7 0.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding ZZ PF00569.12 EMD65505.1 - 7.3e-13 47.8 8.2 1.5e-12 46.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EMD65505.1 - 1.2e-10 39.8 4.3 0.00014 20.8 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMD65505.1 - 2.4e-10 40.3 5.1 7.5e-07 29.2 0.4 3.9 4 1 2 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.1 EMD65505.1 - 1e-08 34.2 2.0 0.012 15.3 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EMD65505.1 - 7.7e-06 25.4 3.5 0.13 11.9 0.0 4.6 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EMD65505.1 - 0.0057 15.9 3.1 2.7 7.4 0.0 3.1 3 0 0 3 3 3 2 EF hand FA_desaturase PF00487.19 EMD65506.1 - 1.6e-13 50.7 24.2 2.5e-13 50.0 16.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF1378 PF07125.6 EMD65506.1 - 0.48 10.4 2.3 1.1 9.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Lipase_3 PF01764.20 EMD65507.1 - 8.5e-36 122.6 0.0 1.5e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EMD65507.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 EMD65507.1 - 0.00084 18.7 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EMD65507.1 - 0.0022 17.7 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EMD65507.1 - 0.0023 17.4 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 EMD65507.1 - 0.0041 17.0 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMD65507.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 EMD65507.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EMD65507.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 EMD65507.1 - 0.054 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 EMD65507.1 - 0.057 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 EMD65507.1 - 0.063 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.13 EMD65507.1 - 0.079 12.2 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 EMD65507.1 - 0.11 11.3 0.2 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Gram_pos_anchor PF00746.16 EMD65509.1 - 0.25 11.1 3.2 0.92 9.3 2.2 2.0 1 0 0 1 1 1 0 Gram positive anchor Chitin_bind_3 PF03067.10 EMD65510.1 - 0.0052 17.0 0.1 0.011 16.0 0.0 1.5 2 0 0 2 2 2 1 Chitin binding domain E1_DerP2_DerF2 PF02221.10 EMD65510.1 - 0.17 12.1 1.4 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 ML domain CBM_19 PF03427.8 EMD65510.1 - 2.8 7.8 20.3 0.6 9.9 5.6 3.4 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) SKG6 PF08693.5 EMD65511.1 - 0.0043 16.3 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Abhydrolase_6 PF12697.2 EMD65513.1 - 1.6e-06 28.2 0.1 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65513.1 - 3.6e-06 26.7 0.0 8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family GTP_EFTU PF00009.22 EMD65514.1 - 6.7e-56 188.7 0.3 1.4e-55 187.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMD65514.1 - 2.8e-33 113.5 0.0 6.4e-33 112.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EMD65514.1 - 2e-31 108.0 0.1 4.2e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMD65514.1 - 1.4e-23 82.5 0.0 1.4e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD65514.1 - 3.4e-14 52.6 0.0 7.6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EMD65514.1 - 0.025 14.4 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) RdRP PF05183.7 EMD65516.1 - 3.6e-179 597.1 0.0 4.6e-179 596.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase O-ag_pol_Wzy PF14296.1 EMD65516.1 - 0.15 10.6 0.1 0.23 10.0 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF3176 PF11374.3 EMD65518.1 - 1.3e-28 99.0 0.4 1.3e-28 99.0 0.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) Thia_YuaJ PF09515.5 EMD65518.1 - 0.0032 17.2 0.4 0.0047 16.7 0.2 1.2 1 0 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) DUF2348 PF09807.4 EMD65519.1 - 0.0081 15.2 0.0 0.5 9.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EMD65519.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC Rdx PF10262.4 EMD65523.1 - 2.8e-27 94.5 0.0 3.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Rdx family SQS_PSY PF00494.14 EMD65524.1 - 6.5e-41 140.3 0.0 1.2e-40 139.4 0.0 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase NPL4 PF05021.10 EMD65524.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 NPL4 family Lactamase_B_4 PF13691.1 EMD65524.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease IF4E PF01652.13 EMD65525.1 - 2.6e-59 199.4 0.2 3.2e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ-X PF14308.1 EMD65526.1 - 1.2e-73 246.8 8.1 1.2e-73 246.8 5.6 2.6 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EMD65526.1 - 2.4e-27 94.4 0.8 7.5e-27 92.8 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 EMD65526.1 - 0.0037 16.6 1.4 0.0077 15.6 1.0 1.5 1 0 0 1 1 1 1 Probable transposase Carb_anhydrase PF00194.16 EMD65527.1 - 1.6e-25 89.5 0.0 2.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF221 PF02714.10 EMD65528.1 - 2.4e-86 289.5 10.8 2.4e-86 289.5 7.5 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD65528.1 - 6e-41 139.6 3.9 1.3e-40 138.5 2.7 1.6 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMD65528.1 - 1.3e-17 64.0 0.1 3e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Spt5-NGN PF03439.8 EMD65529.1 - 6e-18 64.3 0.0 1.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EMD65529.1 - 2.1e-15 57.1 13.0 2.1e-15 57.1 9.0 4.2 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EMD65529.1 - 2.4e-13 50.5 54.0 2.8e-08 34.2 29.3 3.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EMD65529.1 - 2.4e-05 23.8 12.3 0.37 10.5 0.1 5.3 5 0 0 5 5 5 3 KOW motif DUF1506 PF07405.6 EMD65529.1 - 0.2 11.6 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) ADH_zinc_N PF00107.21 EMD65530.1 - 1.6e-33 115.0 0.8 2.9e-33 114.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD65530.1 - 4.1e-13 50.3 0.5 4.1e-13 50.3 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD65530.1 - 1.7e-06 27.7 0.0 4.7e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMD65530.1 - 0.00013 22.0 1.2 0.00026 21.0 0.9 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMD65530.1 - 0.00058 19.6 1.0 0.0011 18.6 0.7 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.16 EMD65530.1 - 0.042 13.4 0.4 0.14 11.7 0.5 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMD65530.1 - 0.046 13.7 0.2 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EMD65530.1 - 0.053 13.4 2.4 0.1 12.5 1.7 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ATP-synt_F PF01990.12 EMD65530.1 - 0.058 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit NmrA PF05368.8 EMD65530.1 - 0.13 11.5 0.7 0.18 11.0 0.5 1.2 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.2 EMD65531.1 - 6.1e-17 62.2 0.0 1.2e-16 61.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65531.1 - 5.5e-08 32.6 0.1 3.1e-07 30.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD65531.1 - 0.0013 18.3 0.0 0.0039 16.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 EMD65531.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Isochorismatase PF00857.15 EMD65532.1 - 3.8e-18 66.0 0.0 5.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans_2 PF11951.3 EMD65534.1 - 1.2e-33 116.2 0.0 1.6e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65534.1 - 7.3e-07 29.0 8.7 1.2e-06 28.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUR7 PF06687.7 EMD65535.1 - 5.2e-28 98.0 7.8 6.9e-28 97.6 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S4e PF00900.15 EMD65536.1 - 1.9e-32 110.7 0.5 4.7e-32 109.5 0.3 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EMD65536.1 - 2.8e-16 59.0 2.8 5.1e-16 58.2 2.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EMD65536.1 - 4.2e-06 26.0 0.0 9.3e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EMD65536.1 - 0.00014 21.4 4.0 0.00014 21.4 2.8 3.1 4 0 0 4 4 4 1 KOW motif Semialdhyde_dhC PF02774.13 EMD65537.1 - 2.3e-41 141.7 0.0 2.9e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EMD65537.1 - 3.9e-29 101.4 0.0 1.1e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EMD65537.1 - 0.045 14.2 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EMD65537.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 EMD65537.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain FAD-oxidase_C PF02913.14 EMD65538.1 - 2.2e-64 217.1 0.2 3.6e-64 216.4 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMD65538.1 - 1.2e-32 112.3 0.0 2.1e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF3584 PF12128.3 EMD65539.1 - 6.3e-05 20.5 69.5 0.00078 16.9 21.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) DUF4200 PF13863.1 EMD65539.1 - 0.0026 17.6 22.6 0.0026 17.6 15.6 4.3 1 1 3 4 4 4 1 Domain of unknown function (DUF4200) DUF3439 PF11921.3 EMD65539.1 - 0.0029 17.3 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) BLOC1_2 PF10046.4 EMD65539.1 - 0.0068 16.5 9.4 0.0068 16.5 6.5 5.5 2 1 4 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EMD65539.1 - 0.052 12.0 52.8 0.59 8.5 12.3 2.3 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EMD65539.1 - 0.061 12.5 65.5 0.66 9.1 21.4 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding PID_2 PF14719.1 EMD65539.1 - 3.1 7.4 7.3 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Tropomyosin PF00261.15 EMD65539.1 - 3.5 6.6 71.4 0.024 13.7 24.7 2.3 1 1 1 2 2 2 0 Tropomyosin ERM PF00769.14 EMD65539.1 - 3.8 6.9 74.4 0.2 11.1 17.4 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 EMD65539.1 - 6.5 6.1 66.9 1.3 8.4 8.2 4.1 1 1 2 3 3 3 0 Intermediate filament protein PspA_IM30 PF04012.7 EMD65539.1 - 6.8 5.9 63.7 3.3 7.0 15.4 3.4 1 1 2 3 3 3 0 PspA/IM30 family DUF972 PF06156.8 EMD65539.1 - 7.3 6.9 55.9 0.33 11.3 2.6 5.4 2 2 3 5 5 5 0 Protein of unknown function (DUF972) Pyr_redox_3 PF13738.1 EMD65540.1 - 2.4e-25 89.7 0.0 1.7e-21 77.2 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD65540.1 - 3e-14 52.1 0.4 1.5e-13 49.7 0.1 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD65540.1 - 9.8e-12 44.4 0.4 3.5e-08 32.7 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMD65540.1 - 8.3e-09 34.8 0.0 0.0015 17.4 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD65540.1 - 3.9e-07 30.0 0.0 8.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD65540.1 - 6.3e-07 29.4 0.0 0.014 15.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD65540.1 - 1.3e-05 25.0 0.8 0.019 14.7 0.2 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMD65540.1 - 7.2e-05 21.8 0.2 0.027 13.4 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 EMD65540.1 - 0.0036 16.2 0.1 0.063 12.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Mqo PF06039.10 EMD65540.1 - 0.054 11.6 0.1 1.2 7.1 0.0 2.4 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 EMD65540.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMD65540.1 - 0.13 10.6 0.2 12 4.2 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 EMD65540.1 - 0.15 11.1 1.4 0.37 9.8 0.0 2.1 3 0 0 3 3 3 0 Thi4 family ABC2_membrane PF01061.19 EMD65541.1 - 6.2e-38 130.0 21.9 1e-37 129.3 15.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMD65541.1 - 6.8e-28 97.6 0.0 1.2e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMD65541.1 - 1.8e-09 38.0 0.1 7.7e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMD65541.1 - 1e-07 31.3 33.7 1e-07 31.3 23.3 2.2 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_17 PF13207.1 EMD65541.1 - 0.0014 19.3 0.0 0.0041 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD65541.1 - 0.0051 16.2 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD65541.1 - 0.036 13.2 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMD65541.1 - 0.041 13.4 0.1 0.085 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EMD65541.1 - 0.084 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD65541.1 - 0.087 13.1 0.0 0.32 11.2 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EMD65541.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 EMD65541.1 - 0.15 11.0 0.0 8.7 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 EMD65541.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMD65541.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 EMD65541.1 - 0.65 8.8 25.3 0.0098 14.7 7.9 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein Aminotran_1_2 PF00155.16 EMD65542.1 - 1.3e-41 142.7 0.0 1.7e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMD65542.1 - 4.5e-07 28.9 0.0 8.5e-07 28.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMD65542.1 - 4.6e-06 25.1 0.0 6.5e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMD65542.1 - 4.9e-06 25.8 0.0 7.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMD65542.1 - 0.00037 19.6 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EMD65542.1 - 0.036 12.7 0.2 0.37 9.3 0.1 2.2 1 1 1 2 2 2 0 Allinase Shisa PF13908.1 EMD65543.1 - 0.13 12.3 0.2 0.15 12.2 0.2 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Biotin_lipoyl PF00364.17 EMD65545.1 - 5.9e-21 73.8 0.4 1.3e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMD65545.1 - 2.4e-06 27.0 2.1 0.00013 21.5 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 EMD65545.1 - 2.6e-05 23.7 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 e3 binding domain HlyD_2 PF12700.2 EMD65545.1 - 0.0012 18.0 0.3 0.069 12.3 0.2 2.2 1 1 1 2 2 2 2 HlyD family secretion protein QRPTase_N PF02749.11 EMD65545.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain E1-E2_ATPase PF00122.15 EMD65546.1 - 1.5e-65 220.4 2.6 1.5e-65 220.4 1.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD65546.1 - 2.8e-32 111.7 9.3 2.8e-32 111.7 6.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD65546.1 - 4.9e-32 112.1 0.1 5.4e-28 98.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD65546.1 - 4.9e-18 64.8 0.0 9.8e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD65546.1 - 1.4e-15 57.9 0.0 3.8e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD65546.1 - 2e-15 55.9 0.0 5.2e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD65546.1 - 5.2e-05 22.9 0.1 0.00053 19.6 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 EMD65546.1 - 0.17 10.4 4.0 0.1 11.1 0.1 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TauD PF02668.11 EMD65547.1 - 3.2e-52 177.7 0.2 4.2e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.14 EMD65548.1 - 6.5e-30 103.8 0.2 7.8e-21 73.8 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMD65548.1 - 4.3e-18 66.1 0.2 1.4e-17 64.4 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD65548.1 - 2.7e-12 47.0 0.0 2.7e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD65548.1 - 2.9e-10 40.0 0.0 7.2e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD65548.1 - 5.4e-09 35.4 4.2 1.9e-06 27.0 1.2 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD65548.1 - 3.2e-07 30.2 2.4 0.0037 17.0 0.1 3.5 2 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD65548.1 - 8e-07 28.2 0.8 0.00015 20.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EMD65548.1 - 5.5e-06 25.7 0.5 0.014 14.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EMD65548.1 - 3.2e-05 23.1 0.0 5.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMD65548.1 - 4.3e-05 23.8 0.3 0.00066 20.0 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD65548.1 - 0.00037 19.0 0.9 0.0014 17.1 0.6 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMD65548.1 - 0.0019 17.1 0.4 0.0042 15.9 0.3 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMD65548.1 - 0.0019 17.1 1.0 0.0045 15.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 EMD65548.1 - 0.0047 16.6 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMD65548.1 - 0.0061 15.6 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EMD65548.1 - 0.0082 16.1 0.4 1.3 8.9 0.1 2.3 2 0 0 2 2 2 1 NADH(P)-binding FAD_binding_3 PF01494.14 EMD65548.1 - 0.027 13.5 1.2 0.051 12.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EMD65548.1 - 0.031 14.3 0.1 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EMD65548.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMD65548.1 - 0.043 13.1 0.1 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EMD65548.1 - 0.054 12.9 0.9 0.16 11.4 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EMD65548.1 - 0.11 12.8 0.1 0.49 10.6 0.1 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EMD65548.1 - 0.3 10.6 1.7 0.37 10.3 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 EMD65549.1 - 1.7e-34 119.1 6.2 1.7e-34 119.1 4.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PQ-loop PF04193.9 EMD65550.1 - 6.3e-34 115.3 8.7 1.2e-17 63.1 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat ATG27 PF09451.5 EMD65550.1 - 0.36 10.0 1.8 0.52 9.4 1.3 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Polyketide_cyc2 PF10604.4 EMD65551.1 - 4.7e-05 23.5 0.1 0.00031 20.9 0.0 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EMD65551.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Barstar PF01337.13 EMD65551.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) PALP PF00291.20 EMD65553.1 - 4.4e-75 252.7 0.3 5.8e-75 252.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EMD65553.1 - 8.2e-45 150.3 0.0 2e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase His_Phos_2 PF00328.17 EMD65554.1 - 1.3e-07 31.2 0.0 1.7e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Septin PF00735.13 EMD65555.1 - 1.2e-34 119.6 0.0 1e-11 44.3 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EMD65555.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EMD65555.1 - 0.0065 16.3 0.3 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 EMD65555.1 - 0.017 15.1 0.2 0.075 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EMD65555.1 - 0.022 15.2 0.0 0.062 13.8 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EMD65555.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 EMD65555.1 - 0.043 12.6 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.15 EMD65555.1 - 0.068 11.8 0.0 0.068 11.8 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit AAA_17 PF13207.1 EMD65555.1 - 0.46 11.3 2.4 2.1 9.1 1.7 2.2 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 EMD65556.1 - 6e-10 39.2 0.0 9.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD65556.1 - 2.5e-06 27.3 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD65556.1 - 0.033 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Yae1_N PF09811.4 EMD65557.1 - 4.3e-11 42.1 2.2 7e-11 41.4 1.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ABC1 PF03109.11 EMD65558.1 - 3e-20 72.3 0.0 6.9e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family PNRC PF15365.1 EMD65558.1 - 0.0037 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator ECH PF00378.15 EMD65559.1 - 6.5e-27 94.2 0.1 8.4e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FAA_hydrolase PF01557.13 EMD65560.1 - 1.7e-51 174.7 0.0 2.3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family E1-E2_ATPase PF00122.15 EMD65561.1 - 1.8e-55 187.5 1.0 1.8e-55 187.5 0.7 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD65561.1 - 1.3e-38 132.3 8.1 1.3e-38 132.3 5.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD65561.1 - 7.8e-29 101.6 1.2 9e-28 98.1 0.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD65561.1 - 3.7e-18 65.2 0.0 8.6e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD65561.1 - 2.1e-15 57.3 0.1 4.7e-15 56.2 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD65561.1 - 7.5e-14 50.9 0.1 3.7e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD65561.1 - 0.00028 20.5 0.2 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_11 PF08279.7 EMD65561.1 - 0.0081 15.7 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 HTH domain DUF2207 PF09972.4 EMD65561.1 - 0.46 9.0 1.2 17 3.8 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) p450 PF00067.17 EMD65562.1 - 7.3e-44 150.0 0.0 1.7e-39 135.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1996 PF09362.5 EMD65563.1 - 1.2e-76 257.4 0.1 1.6e-76 257.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_3 PF01494.14 EMD65565.1 - 9.1e-23 80.8 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD65565.1 - 2.2e-06 27.9 0.1 0.00048 20.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMD65565.1 - 0.00023 20.0 0.0 0.00052 18.9 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EMD65565.1 - 0.00051 20.0 0.2 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD65565.1 - 0.0013 17.6 0.1 0.0028 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMD65565.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMD65565.1 - 0.0023 17.8 0.1 0.0084 16.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD65565.1 - 0.0096 14.4 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 EMD65565.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMD65565.1 - 0.044 12.8 2.1 0.44 9.5 1.4 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMD65565.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M24 PF00557.19 EMD65566.1 - 3.4e-41 141.1 0.1 4.4e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EMD65566.1 - 0.00065 19.5 10.0 0.00065 19.5 6.9 2.3 2 0 0 2 2 2 1 MYND finger DUF2116 PF09889.4 EMD65566.1 - 0.083 12.7 1.7 0.18 11.6 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-HIT PF04438.11 EMD65566.1 - 0.38 10.4 6.3 1.1 8.9 4.3 1.8 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.9 EMD65567.1 - 3.2e-54 182.4 12.6 3.6e-54 182.3 8.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 EMD65567.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) WD40 PF00400.27 EMD65568.1 - 2.8e-36 122.0 6.3 2e-10 40.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMD65568.1 - 0.0076 15.0 0.0 0.2 10.4 0.0 2.5 2 1 0 3 3 3 1 Coatomer WD associated region Nup160 PF11715.3 EMD65568.1 - 0.0079 14.3 0.1 0.022 12.9 0.0 1.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Chromate_transp PF02417.10 EMD65570.1 - 1.3e-53 181.1 37.0 5.5e-28 97.6 10.0 2.4 3 0 0 3 3 3 2 Chromate transporter DUF4066 PF13278.1 EMD65571.1 - 1.1e-21 76.8 0.1 3.6e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD65571.1 - 2.5e-07 30.2 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family PIG-S PF10510.4 EMD65572.1 - 5.1e-162 540.1 3.8 5.9e-162 539.9 2.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Beta-lactamase PF00144.19 EMD65573.1 - 3.2e-38 131.5 0.2 1.4e-37 129.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase DUF1932 PF09130.6 EMD65574.1 - 1.6e-19 69.3 0.0 3.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EMD65574.1 - 6.1e-06 26.1 0.1 2.2e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMD65574.1 - 1.3e-05 25.5 0.2 2.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMD65574.1 - 0.033 13.5 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EMD65574.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MARVEL PF01284.18 EMD65576.1 - 8.9e-13 48.2 16.6 1.1e-12 48.0 11.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Abhydrolase_5 PF12695.2 EMD65577.1 - 2.7e-07 30.4 0.2 5.7e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PIP5K PF01504.13 EMD65578.1 - 8.6e-60 201.9 1.4 1.9e-59 200.7 1.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EMD65578.1 - 1.3e-30 106.4 0.0 2.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EMD65578.1 - 4.5e-14 52.0 7.2 4.5e-14 52.0 5.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EMD65578.1 - 0.65 9.7 7.4 0.15 11.8 2.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.4 EMD65579.1 - 0.071 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD p450 PF00067.17 EMD65580.1 - 9.2e-53 179.3 0.0 1.3e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMD65580.1 - 9.6e-18 64.0 33.4 1.9e-10 40.0 5.9 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD65580.1 - 7.3e-05 22.4 0.3 0.33 10.7 0.1 2.7 2 0 0 2 2 2 2 MFS_1 like family DUF2264 PF10022.4 EMD65580.1 - 0.17 10.5 0.0 0.48 9.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2264) F-box-like PF12937.2 EMD65581.1 - 2.9e-08 33.3 1.1 6.5e-08 32.1 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD65581.1 - 0.0006 19.3 1.8 0.0008 18.9 0.1 2.1 2 0 0 2 2 2 1 F-box domain Ribosomal_L37e PF01907.14 EMD65582.1 - 2.4e-27 94.4 11.9 4.2e-27 93.7 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EMD65582.1 - 0.0023 17.6 1.9 0.0037 17.0 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EMD65582.1 - 0.079 12.1 1.5 0.2 10.8 1.0 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMD65582.1 - 0.73 9.3 2.9 19 4.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 EMD65582.1 - 1.9 8.2 5.5 3.1 7.5 3.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 EMD65582.1 - 5.2 6.5 11.1 3.2 7.1 0.1 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e Sugar_tr PF00083.19 EMD65583.1 - 3.1e-41 141.3 22.7 4.4e-41 140.9 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65583.1 - 5.8e-22 77.8 39.7 6.5e-19 67.8 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EMD65584.1 - 1.2e-27 96.5 61.9 2.9e-24 85.4 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAP PF02037.22 EMD65585.1 - 1.3e-11 43.6 0.5 2.4e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 SAP domain DUF3452 PF11934.3 EMD65586.1 - 0.018 14.3 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF445 PF04286.7 EMD65586.1 - 0.03 13.8 0.9 0.031 13.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RNA_pol_Rpb5_C PF01191.14 EMD65586.1 - 0.092 12.3 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF3627 PF12299.3 EMD65586.1 - 0.21 11.6 1.2 0.62 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) Romo1 PF10247.4 EMD65588.1 - 8.9e-24 83.4 11.3 1.1e-23 83.1 7.8 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EMD65588.1 - 0.038 14.0 3.4 0.056 13.4 2.4 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Form-deh_trans PF09163.6 EMD65588.1 - 5 6.7 5.6 4.8 6.7 0.2 2.4 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane FHA PF00498.21 EMD65589.1 - 3.4e-16 59.1 0.1 8.6e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain BLOC1_2 PF10046.4 EMD65589.1 - 0.02 15.0 9.3 0.15 12.1 0.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hormone_1 PF00103.15 EMD65589.1 - 0.21 10.8 3.5 0.089 12.1 0.4 1.8 2 0 0 2 2 2 0 Somatotropin hormone family TBPIP PF07106.8 EMD65589.1 - 1.5 8.3 13.6 0.76 9.2 1.0 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EMD65589.1 - 5.3 7.4 12.1 0.39 11.0 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) SlyX PF04102.7 EMD65589.1 - 5.8 7.3 13.8 3.9 7.9 0.3 3.6 3 0 0 3 3 3 0 SlyX CENP-Q PF13094.1 EMD65589.1 - 8.7 6.3 21.0 0.75 9.8 9.4 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Rpp20 PF12328.3 EMD65590.1 - 4.6e-37 126.8 0.0 7.9e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EMD65590.1 - 1.5e-14 53.3 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Alba WWbp PF10349.4 EMD65590.1 - 8.8 7.2 11.7 20 6.0 8.1 1.6 1 0 0 1 1 1 0 WW-domain ligand protein BPL_LplA_LipB PF03099.14 EMD65591.1 - 6.6e-16 58.4 0.0 9.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RRM_1 PF00076.17 EMD65592.1 - 3.2e-10 39.5 0.0 1e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD65592.1 - 1.4e-07 31.3 0.1 3.3e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD65592.1 - 0.0005 19.8 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LisH PF08513.6 EMD65594.1 - 0.00028 20.5 0.0 0.00065 19.3 0.0 1.7 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EMD65594.1 - 0.00048 19.9 6.4 0.25 11.2 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EMD65594.1 - 0.082 13.2 0.1 21 5.5 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain SET PF00856.23 EMD65595.1 - 2.9e-06 27.6 0.1 0.037 14.3 0.0 2.7 3 0 0 3 3 3 2 SET domain zf-MYND PF01753.13 EMD65595.1 - 0.0032 17.2 7.7 0.013 15.3 5.3 2.1 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.1 EMD65595.1 - 0.066 13.8 0.8 18 6.3 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-CHY PF05495.7 EMD65595.1 - 0.52 10.5 8.8 0.073 13.2 2.0 2.5 3 0 0 3 3 3 0 CHY zinc finger Septin PF00735.13 EMD65596.1 - 1.6e-15 56.8 0.0 3.4e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMD65596.1 - 2.6e-07 30.5 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMD65596.1 - 0.00023 21.0 0.1 0.0014 18.4 0.0 2.4 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EMD65596.1 - 0.00078 19.9 0.0 0.0022 18.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EMD65596.1 - 0.0062 15.7 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EMD65596.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EMD65596.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EMD65596.1 - 0.017 15.3 0.0 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 EMD65596.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EMD65596.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EMD65596.1 - 0.024 13.5 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EMD65596.1 - 0.029 14.0 0.0 0.089 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EMD65596.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMD65596.1 - 0.061 12.7 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 EMD65596.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EMD65596.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NTF2 PF02136.15 EMD65597.1 - 1.9e-23 83.0 0.6 1.9e-23 83.0 0.4 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EMD65597.1 - 1.2e-08 34.4 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD65597.1 - 3e-07 30.3 0.0 6.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD65597.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD65597.1 - 0.00015 21.5 0.0 0.00044 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Baculo_PEP_C PF04513.7 EMD65598.1 - 0.002 17.9 1.8 0.0035 17.1 1.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4381 PF14316.1 EMD65598.1 - 0.032 14.3 0.6 0.043 13.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FtsQ PF03799.10 EMD65598.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Cell division protein FtsQ NPV_P10 PF05531.7 EMD65598.1 - 0.079 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Selenoprotein_S PF06936.6 EMD65598.1 - 2.7 7.4 6.1 5.3 6.5 4.3 1.5 1 1 0 1 1 1 0 Selenoprotein S (SelS) FAD_binding_4 PF01565.18 EMD65599.1 - 1.3e-15 57.1 0.0 3.8e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Git3 PF11710.3 EMD65601.1 - 2.1e-18 66.6 14.6 4.9e-18 65.4 10.2 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EMD65601.1 - 3.7e-07 29.5 12.5 8.4e-07 28.3 7.3 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EMD65601.1 - 4e-07 29.6 0.1 4e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DDE_1 PF03184.14 EMD65603.1 - 1.4e-38 132.2 0.0 1.6e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD65603.1 - 5.2e-06 26.2 0.0 6.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Protocadherin PF08374.6 EMD65604.1 - 0.026 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 EMD65604.1 - 0.15 12.5 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1675 PF07897.6 EMD65604.1 - 0.16 11.7 11.7 0.13 12.0 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Ribosomal_S8 PF00410.14 EMD65607.1 - 9.7e-23 80.4 0.0 3.1e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 MARVEL PF01284.18 EMD65608.1 - 0.00085 19.1 15.2 0.0013 18.5 10.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2721 PF11026.3 EMD65608.1 - 0.92 9.1 6.2 3 7.4 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) EMP70 PF02990.11 EMD65608.1 - 3.3 6.0 6.4 1.4 7.2 2.9 1.4 2 0 0 2 2 2 0 Endomembrane protein 70 DUF1469 PF07332.6 EMD65608.1 - 3.8 7.2 0.0 3.8 7.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) IMS PF00817.15 EMD65610.1 - 5.6e-40 136.5 0.4 9.5e-40 135.8 0.3 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMD65610.1 - 9.2e-18 64.4 0.1 1.9e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMD65610.1 - 0.00022 21.0 0.0 0.00064 19.6 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif AT_hook PF02178.14 EMD65610.1 - 0.24 11.1 5.2 1.6 8.6 0.7 2.7 2 0 0 2 2 2 0 AT hook motif Tnp_P_element PF12017.3 EMD65611.1 - 0.64 9.2 3.2 0.7 9.0 0.3 2.0 2 0 0 2 2 2 0 Transposase protein Zip PF02535.17 EMD65612.1 - 1.2e-58 198.6 9.3 1.4e-58 198.4 6.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Bac_rhodopsin PF01036.13 EMD65613.1 - 3.5e-45 154.0 18.9 4.1e-45 153.7 13.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DuoxA PF10204.4 EMD65613.1 - 0.011 14.8 3.1 0.011 14.8 2.1 2.2 2 1 1 3 3 3 0 Dual oxidase maturation factor DUF1129 PF06570.6 EMD65613.1 - 8.3 5.6 12.3 2.4 7.4 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RPEL PF02755.10 EMD65614.1 - 1.5e-29 100.5 11.9 1.1e-10 40.4 0.3 3.4 3 0 0 3 3 3 3 RPEL repeat PPV_E1_N PF00524.13 EMD65614.1 - 0.22 11.7 1.2 2.3 8.4 0.8 2.1 1 1 0 1 1 1 0 E1 Protein, N terminal domain Sugar_tr PF00083.19 EMD65615.1 - 1.1e-113 380.1 22.9 1.3e-113 379.9 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65615.1 - 2.6e-16 59.3 22.1 2.6e-16 59.3 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2264 PF10022.4 EMD65616.1 - 1.5e-135 451.5 1.5 1.9e-135 451.2 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) RVT_connect PF06815.8 EMD65616.1 - 0.022 14.6 0.7 0.056 13.3 0.5 1.6 1 0 0 1 1 1 0 Reverse transcriptase connection domain Pkinase PF00069.20 EMD65617.1 - 1.1e-75 254.1 0.0 1.3e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65617.1 - 1.6e-36 125.7 0.0 2.2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD65617.1 - 0.016 14.2 0.2 0.044 12.8 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD65617.1 - 0.024 13.5 0.1 0.084 11.8 0.0 1.8 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 EMD65617.1 - 0.043 13.5 1.5 0.065 12.9 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.13 EMD65619.1 - 1.5e-09 37.6 7.4 2.5e-09 36.8 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD65619.1 - 2e-08 33.4 0.1 4.8e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.11 EMD65620.1 - 7.7e-08 32.2 7.6 1.6e-07 31.2 5.3 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 APC_CDC26 PF10471.4 EMD65620.1 - 0.86 10.3 0.0 0.86 10.3 0.0 4.3 4 1 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 DUF2427 PF10348.4 EMD65620.1 - 6.4 6.4 10.6 0.21 11.1 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) AAA_13 PF13166.1 EMD65621.1 - 0.0025 16.3 2.6 0.0032 16.0 1.8 1.2 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.4 EMD65621.1 - 0.011 15.8 2.7 0.021 14.9 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 EMD65621.1 - 0.018 13.6 10.1 0.078 11.6 3.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Med30 PF11315.3 EMD65621.1 - 0.048 13.7 1.3 0.12 12.4 0.9 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 Syntaxin PF00804.20 EMD65621.1 - 0.065 13.4 0.1 0.065 13.4 0.1 2.8 1 1 1 2 2 2 0 Syntaxin DUF848 PF05852.6 EMD65621.1 - 0.12 12.2 6.1 4 7.2 0.1 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Reo_sigmaC PF04582.7 EMD65621.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 EMD65621.1 - 0.2 11.1 11.3 2.8 7.4 0.2 3.7 3 0 0 3 3 3 0 Septum formation initiator COG5 PF10392.4 EMD65621.1 - 0.77 9.7 8.4 4.2 7.3 1.0 2.8 3 1 0 3 3 3 0 Golgi transport complex subunit 5 GAS PF13851.1 EMD65621.1 - 1.3 8.1 13.8 1.1 8.4 4.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EMD65621.1 - 1.9 7.3 11.6 1.4 7.7 2.1 2.3 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EMD65621.1 - 2 8.3 21.0 0.067 13.1 4.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) GvpK PF05121.7 EMD65621.1 - 2.4 8.0 9.9 2.9 7.7 0.7 3.6 2 1 1 3 3 3 0 Gas vesicle protein K Fez1 PF06818.10 EMD65621.1 - 2.5 8.0 13.8 82 3.1 9.6 2.5 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.6 EMD65621.1 - 2.6 7.8 17.3 1.1 9.0 0.3 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EMD65621.1 - 3 7.7 13.4 1.2 9.0 3.2 3.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bap31 PF05529.7 EMD65621.1 - 4.1 6.8 10.5 1.4 8.3 1.5 3.1 2 2 1 3 3 3 0 B-cell receptor-associated protein 31-like DUF2968 PF11180.3 EMD65621.1 - 4.3 6.6 16.6 0.21 10.9 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) IncA PF04156.9 EMD65621.1 - 6.2 6.3 21.2 0.33 10.5 1.7 2.4 1 1 1 2 2 2 0 IncA protein Ion_trans_2 PF07885.11 EMD65623.1 - 5.1e-25 87.0 29.6 1.5e-14 53.4 4.6 3.5 3 0 0 3 3 3 2 Ion channel DEAD PF00270.24 EMD65624.1 - 1.6e-43 148.0 0.0 1.8e-42 144.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD65624.1 - 8.2e-23 80.0 0.1 2.5e-22 78.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_3 PF07859.8 EMD65624.1 - 1.3e-22 80.4 0.0 4e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EMD65624.1 - 7.9e-05 21.5 0.0 0.00017 20.4 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family DUF1253 PF06862.7 EMD65624.1 - 0.0059 15.0 0.0 0.15 10.3 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EMD65624.1 - 0.073 12.8 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2457 PF10446.4 EMD65626.1 - 4.1e-158 526.8 35.4 4.1e-158 526.8 24.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) HSP90 PF00183.13 EMD65629.1 - 1.7e-244 812.1 31.8 3.1e-243 808.0 22.0 2.0 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EMD65629.1 - 1.2e-11 44.3 1.5 2.4e-11 43.4 0.3 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMD65629.1 - 6.6e-11 41.9 0.1 1.2e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 EMD65629.1 - 0.45 10.8 8.1 0.13 12.5 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1676) PVL_ORF50 PF07768.6 EMD65629.1 - 0.82 9.6 8.6 1 9.3 1.8 2.9 2 0 0 2 2 2 0 PVL ORF-50-like family Glyco_hydro_88 PF07470.8 EMD65630.1 - 6.7e-80 268.6 0.9 7.7e-80 268.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 EMD65631.1 - 1.2e-31 109.7 24.3 1.5e-31 109.4 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Flavin_Reduct PF01613.13 EMD65632.1 - 7.1e-24 84.3 0.0 1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.20 EMD65633.1 - 1.5e-12 47.7 0.4 4.4e-11 42.9 0.3 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD65633.1 - 0.00038 20.1 5.2 0.054 13.1 0.3 3.1 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 EMD65633.1 - 0.00054 19.4 0.0 0.002 17.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMD65633.1 - 0.0017 18.2 0.2 0.004 16.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3049 PF11250.3 EMD65634.1 - 0.049 13.3 0.0 0.049 13.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) zf-Apc11 PF12861.2 EMD65635.1 - 5.5e-43 144.7 8.7 6.5e-43 144.5 6.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMD65635.1 - 4e-33 113.3 10.8 5e-33 113.0 7.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMD65635.1 - 3.5e-09 36.3 13.9 6.6e-09 35.4 9.6 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD65635.1 - 1.3e-05 24.7 11.7 3.1e-05 23.5 8.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD65635.1 - 0.00015 21.3 12.2 0.0053 16.3 8.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD65635.1 - 0.00031 20.6 12.9 0.0037 17.2 8.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD65635.1 - 0.00055 19.6 13.1 0.0038 16.9 9.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EMD65635.1 - 0.0051 16.3 4.4 0.01 15.3 3.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EMD65635.1 - 0.0087 15.9 4.1 0.0087 15.9 2.8 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMD65635.1 - 0.013 15.0 11.2 0.38 10.3 5.8 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EMD65635.1 - 0.014 15.1 3.8 0.018 14.7 2.2 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 EMD65635.1 - 0.014 15.3 14.0 0.11 12.4 9.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HIT PF04438.11 EMD65635.1 - 0.028 14.0 8.5 0.033 13.8 2.3 2.3 2 0 0 2 2 2 0 HIT zinc finger zf-RING-like PF08746.6 EMD65635.1 - 0.29 11.1 9.9 0.75 9.8 6.9 1.8 1 1 0 1 1 1 0 RING-like domain RecR PF02132.10 EMD65635.1 - 0.33 10.4 0.4 0.33 10.4 0.3 2.9 3 0 0 3 3 3 0 RecR protein zf-RING_UBOX PF13445.1 EMD65635.1 - 0.81 9.4 8.4 1 9.1 3.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EMD65635.1 - 1.1 9.3 8.7 5.2 7.2 6.2 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMD65635.1 - 3.6 7.6 8.6 12 5.9 5.9 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.2 EMD65635.1 - 3.9 7.6 12.0 26 4.9 8.3 2.1 1 1 0 1 1 1 0 RING-variant domain Rhodanese PF00581.15 EMD65636.1 - 1.6e-19 70.3 0.0 4.9e-11 42.9 0.0 2.5 2 1 0 2 2 2 2 Rhodanese-like domain RRN9 PF10680.4 EMD65637.1 - 1.2e-12 47.3 1.2 3.9e-12 45.7 0.8 1.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Metallophos_2 PF12850.2 EMD65638.1 - 4.4e-11 42.8 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMD65638.1 - 1.7e-07 30.8 2.6 0.0015 17.9 0.2 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase COesterase PF00135.23 EMD65639.1 - 6e-98 328.8 0.0 7.2e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD65639.1 - 0.00021 20.9 0.2 0.0067 16.0 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD65639.1 - 0.0026 17.0 0.3 0.0045 16.2 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PIG-L PF02585.12 EMD65640.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase NIF3 PF01784.13 EMD65641.1 - 6.1e-13 48.9 0.0 9.6e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) tRNA_SAD PF07973.9 EMD65642.1 - 9.3e-09 35.0 0.9 1.9e-08 34.0 0.2 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EMD65642.1 - 0.0065 14.8 0.0 0.011 14.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) Glyco_hydro_16 PF00722.16 EMD65643.1 - 6.3e-07 28.8 0.2 1.4e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 EMD65644.1 - 1.3e-14 54.6 0.2 2.2e-14 53.8 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD65644.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD65644.1 - 0.036 13.3 0.3 1.1 8.5 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 21 zf-C2H2 PF00096.21 EMD65647.1 - 0.00059 20.0 18.2 0.7 10.3 0.0 5.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD65647.1 - 0.002 18.3 17.7 0.084 13.2 0.0 5.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMD65647.1 - 0.018 14.9 0.6 0.65 9.9 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 EMD65647.1 - 0.11 12.7 1.5 8.1 6.8 0.3 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF230 PF03003.11 EMD65647.1 - 0.17 11.4 0.3 0.32 10.5 0.2 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-C2H2_jaz PF12171.3 EMD65647.1 - 0.4 10.8 2.7 44 4.3 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EMD65647.1 - 5.6 7.4 14.3 0.43 10.9 0.5 4.6 4 1 0 4 4 4 0 Zinc-finger double domain RPN7 PF10602.4 EMD65648.1 - 4.9e-49 166.0 0.9 7.8e-49 165.4 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EMD65648.1 - 4.1e-14 52.7 0.7 7.7e-13 48.6 0.1 2.8 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 EMD65648.1 - 0.0034 17.1 2.3 2.5 8.2 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD65648.1 - 0.011 15.4 0.2 0.5 10.2 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD65648.1 - 0.034 13.7 1.1 5.5 6.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMD65648.1 - 0.061 13.2 0.1 0.45 10.4 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2791 PF10923.3 EMD65648.1 - 0.12 11.0 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) TPR_9 PF13371.1 EMD65648.1 - 0.33 10.8 2.4 4.6 7.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 EMD65649.1 - 2.4e-07 30.5 13.3 4.4e-07 29.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2828 PF11443.3 EMD65650.1 - 3.7e-181 602.9 0.3 4.4e-181 602.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) NADHdh_A3 PF14987.1 EMD65650.1 - 0.035 14.0 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Glyco_transf_34 PF05637.7 EMD65652.1 - 5.5e-38 130.8 0.0 3.6e-37 128.1 0.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_tranf_2_3 PF13641.1 EMD65652.1 - 0.014 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PAN_4 PF14295.1 EMD65653.1 - 0.00083 19.0 1.5 0.0018 17.9 1.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EMD65653.1 - 0.0044 16.6 1.2 0.012 15.2 0.8 1.7 1 0 0 1 1 1 1 PAN-like domain PAN_2 PF08276.6 EMD65653.1 - 0.05 13.4 0.9 0.05 13.4 0.6 1.7 2 0 0 2 2 2 0 PAN-like domain Methyltransf_25 PF13649.1 EMD65654.1 - 9.5e-09 35.5 0.1 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD65654.1 - 5.9e-06 25.9 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD65654.1 - 6.4e-05 23.3 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD65654.1 - 9.1e-05 23.0 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD65654.1 - 0.0013 18.4 0.1 0.0021 17.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD65654.1 - 0.0025 16.9 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMD65654.1 - 0.037 14.0 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mannosyl_trans PF05007.8 EMD65656.1 - 6.8e-78 261.8 17.5 1.1e-77 261.2 12.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EMD65656.1 - 2.7e-15 56.1 5.4 2.7e-15 56.1 3.7 1.8 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U PEN-2 PF10251.4 EMD65656.1 - 0.22 11.7 14.0 0.091 12.9 0.7 3.8 2 1 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Translin PF01997.11 EMD65657.1 - 6.4e-53 179.3 0.1 9.6e-53 178.7 0.0 1.3 1 1 0 1 1 1 1 Translin family PIN_4 PF13638.1 EMD65658.1 - 0.00013 22.1 0.1 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 PIN domain ABC_membrane PF00664.18 EMD65660.1 - 2e-72 243.9 33.4 1.7e-37 129.3 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD65660.1 - 4.8e-59 198.5 0.0 4.8e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD65660.1 - 1.7e-13 50.3 1.3 0.00038 19.7 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD65660.1 - 4.9e-11 43.1 0.3 0.13 12.2 0.0 4.7 4 1 0 4 4 4 3 AAA domain AAA_22 PF13401.1 EMD65660.1 - 2.4e-09 37.4 0.1 0.00034 20.7 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMD65660.1 - 3.9e-09 35.8 1.4 0.0019 17.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD65660.1 - 1.3e-08 34.5 0.2 0.045 13.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMD65660.1 - 1.7e-08 35.3 0.1 0.012 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD65660.1 - 2e-08 34.4 0.3 0.00022 21.2 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EMD65660.1 - 2e-06 27.0 0.0 0.071 12.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMD65660.1 - 2.3e-06 27.9 0.0 0.053 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMD65660.1 - 7.7e-06 24.7 0.7 0.0015 17.1 0.1 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class DUF87 PF01935.12 EMD65660.1 - 0.00011 22.1 1.1 0.056 13.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EMD65660.1 - 0.00024 20.9 0.3 0.56 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EMD65660.1 - 0.00053 19.5 0.1 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 EMD65660.1 - 0.00092 17.8 0.0 0.48 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) MobB PF03205.9 EMD65660.1 - 0.0015 18.2 0.4 2.4 7.8 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EMD65660.1 - 0.0055 16.3 0.5 3.3 7.3 0.1 3.1 3 0 0 3 3 3 1 NACHT domain AAA_5 PF07728.9 EMD65660.1 - 0.0078 15.9 0.1 5.5 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EMD65660.1 - 0.009 16.3 0.7 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EMD65660.1 - 0.0097 16.3 0.0 7.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Sigma54_activat PF00158.21 EMD65660.1 - 0.014 14.9 0.1 12 5.3 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EMD65660.1 - 0.03 14.4 0.2 10 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 EMD65660.1 - 0.038 13.0 7.8 2.9 6.9 0.1 3.6 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.4 EMD65660.1 - 0.058 12.3 0.7 6.4 5.6 0.0 3.1 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 EMD65660.1 - 0.07 12.7 0.1 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.1 EMD65660.1 - 0.072 13.0 0.6 6.5 6.7 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EMD65660.1 - 0.088 12.2 3.6 12 5.3 0.0 3.5 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EMD65660.1 - 0.093 12.6 0.1 17 5.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 EMD65660.1 - 0.12 11.9 0.1 2.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EMD65660.1 - 0.14 11.5 12.6 0.14 11.5 0.3 3.6 5 0 0 5 5 3 0 AAA-like domain AAA_24 PF13479.1 EMD65660.1 - 2 7.9 4.0 23 4.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain CbiA PF01656.18 EMD65660.1 - 2.2 7.6 5.0 21 4.4 0.1 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Polysacc_synt_4 PF04669.8 EMD65661.1 - 1.8e-26 92.6 1.6 1e-25 90.2 1.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2161 PF09929.4 EMD65661.1 - 0.059 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Rota_NSP4 PF01452.11 EMD65661.1 - 0.061 12.6 2.7 0.037 13.3 0.8 1.4 2 0 0 2 2 2 0 Rotavirus non structural protein Elongin_A PF06881.6 EMD65661.1 - 0.13 12.6 3.0 0.19 12.1 2.1 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A UPF0158 PF03682.8 EMD65661.1 - 0.23 11.0 2.7 0.35 10.4 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) TryThrA_C PF12319.3 EMD65661.1 - 0.7 9.0 6.7 0.18 10.9 0.7 2.4 3 0 0 3 3 3 0 Tryptophan-Threonine-rich plasmodium antigen C terminal WD40 PF00400.27 EMD65662.1 - 1.7e-19 68.8 20.0 8.7e-08 31.7 0.1 9.8 9 0 0 9 9 9 7 WD domain, G-beta repeat BRCT PF00533.21 EMD65663.1 - 3.3e-06 27.1 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain FSH1 PF03959.8 EMD65664.1 - 1.3e-63 214.3 0.0 1.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EMD65664.1 - 4.6e-07 29.7 0.0 6.5e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD65664.1 - 3.7e-06 26.9 1.1 2.5e-05 24.2 0.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EMD65664.1 - 0.049 13.3 0.0 0.62 9.7 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EMD65664.1 - 0.049 12.8 0.0 0.79 8.9 0.0 2.4 2 1 1 3 3 3 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMD65664.1 - 0.14 11.5 0.0 28 4.0 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PCI PF01399.22 EMD65665.1 - 4.3e-20 71.9 0.0 1.5e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain Asp_Glu_race_2 PF14669.1 EMD65665.1 - 0.0092 15.3 0.3 0.046 13.0 0.0 2.0 2 0 0 2 2 2 1 Putative aspartate racemase Pkinase PF00069.20 EMD65666.1 - 5.5e-21 74.8 0.1 1.1e-12 47.6 0.0 3.5 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65666.1 - 0.00036 19.7 0.1 0.00066 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD65666.1 - 0.067 12.2 1.6 0.25 10.3 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EMD65667.1 - 0.0008 18.5 0.0 0.0029 16.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMD65667.1 - 0.0076 15.4 0.0 0.046 12.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Reticulon PF02453.12 EMD65668.1 - 3.2e-18 65.9 0.1 4.8e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Reticulon Phasin_2 PF09361.5 EMD65668.1 - 0.15 12.0 3.3 0.51 10.3 1.9 2.2 1 1 0 1 1 1 0 Phasin protein PHO4 PF01384.15 EMD65669.1 - 1e-108 362.8 8.9 1.2e-108 362.6 6.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Caveolin PF01146.12 EMD65669.1 - 0.094 12.2 0.9 0.3 10.6 0.6 1.8 1 0 0 1 1 1 0 Caveolin Mito_carr PF00153.22 EMD65670.1 - 7.6e-73 240.3 1.8 1.8e-25 88.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EMD65670.1 - 4.1e-15 53.8 2.5 0.00014 20.9 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMD65670.1 - 1.7e-14 52.3 3.2 8.8e-05 22.0 0.0 6.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EMD65670.1 - 4.8e-13 49.0 4.0 2.7e-05 24.2 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EMD65670.1 - 1.8e-12 46.6 1.5 0.00016 21.2 0.1 4.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMD65670.1 - 2.4e-09 36.0 5.0 0.0057 15.9 0.1 4.4 4 0 0 4 4 4 3 EF hand zf-C2H2_4 PF13894.1 EMD65671.1 - 3.5e-07 30.0 12.5 0.00076 19.6 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD65671.1 - 7.3e-06 26.0 11.5 0.006 16.8 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD65671.1 - 0.0021 18.2 15.4 0.038 14.2 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EMD65671.1 - 0.082 13.0 6.9 0.27 11.3 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PT PF04886.7 EMD65672.1 - 0.0019 17.4 10.9 0.071 12.4 7.6 2.9 1 1 0 1 1 1 1 PT repeat DUF605 PF04652.11 EMD65672.1 - 0.087 12.2 16.3 0.1 11.9 11.3 1.1 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 EMD65673.1 - 5.8e-45 153.5 43.9 7e-45 153.2 29.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD65673.1 - 1.9e-10 39.9 9.4 1.9e-10 39.9 6.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3040 PF11239.3 EMD65673.1 - 1.7 8.7 10.0 0.71 9.9 1.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) SMC_N PF02463.14 EMD65674.1 - 9.2e-60 201.5 9.3 2.3e-58 197.0 6.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMD65674.1 - 2.6e-24 85.5 0.0 1.4e-23 83.1 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMD65674.1 - 1.2e-12 48.3 0.7 6e-05 23.1 0.0 3.2 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EMD65674.1 - 1.7e-08 33.8 0.0 3.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMD65674.1 - 0.0005 19.9 0.0 0.033 14.1 0.0 3.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ADIP PF11559.3 EMD65674.1 - 0.0037 17.1 11.6 0.0037 17.1 8.0 8.9 5 2 4 9 9 9 3 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMD65674.1 - 0.27 10.3 18.6 0.37 9.9 0.7 4.3 3 2 1 5 5 5 0 Reovirus sigma C capsid protein DUF2838 PF10998.3 EMD65675.1 - 6.6e-45 151.5 10.3 6.6e-45 151.5 7.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 EMD65675.1 - 0.44 9.4 4.8 0.8 8.5 3.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Val_tRNA-synt_C PF10458.4 EMD65675.1 - 0.63 10.1 3.8 22 5.2 0.0 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm NAD_binding_8 PF13450.1 EMD65676.1 - 1.9e-12 47.0 0.3 5.2e-12 45.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD65676.1 - 1.3e-08 34.1 0.0 5.7e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD65676.1 - 2.6e-07 30.7 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD65676.1 - 2.5e-06 27.8 0.1 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD65676.1 - 3.3e-06 27.3 0.3 0.00031 20.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD65676.1 - 1.9e-05 23.7 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMD65676.1 - 8.9e-05 22.3 0.1 0.0049 16.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD65676.1 - 9.7e-05 20.9 0.1 0.0029 16.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EMD65676.1 - 0.00033 19.6 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DUF2628 PF10947.3 EMD65676.1 - 0.0018 18.0 1.4 0.0043 16.8 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) Thi4 PF01946.12 EMD65676.1 - 0.013 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EMD65676.1 - 0.014 14.5 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 EMD65676.1 - 0.028 13.5 0.1 0.32 10.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EMD65676.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMD65676.1 - 0.074 12.4 0.1 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 EMD65676.1 - 0.24 10.9 0.0 0.4 10.1 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Peptidase_C50 PF03568.12 EMD65677.1 - 3.3e-103 345.3 0.0 5.9e-103 344.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 Fungal_trans PF04082.13 EMD65677.1 - 1.3e-25 89.7 1.5 3e-25 88.5 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_8 PF13181.1 EMD65677.1 - 0.0025 17.4 0.1 0.11 12.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Zn_clus PF00172.13 EMD65677.1 - 0.0028 17.5 11.1 0.0058 16.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 EMD65677.1 - 0.58 10.2 11.0 14 5.8 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Git3 PF11710.3 EMD65678.1 - 3.4e-22 79.0 18.4 5.3e-22 78.3 12.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMD65678.1 - 7.9e-06 25.5 0.2 7.9e-06 25.5 0.1 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EMD65678.1 - 0.0097 14.8 14.6 0.016 14.1 10.1 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor zf-C2H2_4 PF13894.1 EMD65681.1 - 0.049 13.9 0.7 0.049 13.9 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD65681.1 - 0.7 10.3 8.8 1.8 9.0 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF221 PF02714.10 EMD65682.1 - 2.7e-91 305.8 17.0 2.7e-91 305.8 11.8 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD65682.1 - 1.9e-39 134.7 1.6 4.4e-39 133.5 1.1 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMD65682.1 - 7.3e-25 86.6 0.9 1.6e-24 85.5 0.1 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EMD65682.1 - 2.3e-08 34.4 0.6 2.3e-08 34.4 0.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4463) GMC_oxred_N PF00732.14 EMD65683.1 - 9.6e-62 208.7 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD65683.1 - 8e-35 120.2 0.0 1.6e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD65683.1 - 2.6e-05 23.3 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD65683.1 - 0.0012 17.8 0.8 0.0055 15.6 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMD65683.1 - 0.0021 18.1 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD65683.1 - 0.0039 17.1 0.3 0.016 15.1 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD65683.1 - 0.019 13.9 0.3 0.032 13.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EMD65683.1 - 0.044 12.8 0.1 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EMD65683.1 - 0.053 13.5 0.2 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EMD65683.1 - 0.083 11.3 0.2 0.36 9.2 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein CitT PF12431.3 EMD65683.1 - 0.13 12.3 0.1 0.34 11.0 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator WD40 PF00400.27 EMD65684.1 - 1.2e-09 37.6 16.7 3.7e-07 29.7 0.4 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EMD65684.1 - 0.0012 18.3 0.0 0.02 14.3 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Gryzun-like PF12742.2 EMD65684.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Nbas_N PF15492.1 EMD65684.1 - 0.042 12.9 0.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cep57_CLD_2 PF14197.1 EMD65684.1 - 0.21 11.5 2.4 0.48 10.3 1.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Peptidase_C65 PF10275.4 EMD65685.1 - 3.9e-69 232.7 0.0 4.8e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EMD65685.1 - 0.011 16.3 0.0 2.9 8.5 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease Defensin_beta PF00711.14 EMD65686.1 - 0.074 12.9 2.1 0.074 12.9 1.4 2.3 2 0 0 2 2 2 0 Beta defensin PCI PF01399.22 EMD65688.1 - 5.4e-21 74.8 1.2 9.7e-21 74.0 0.3 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMD65688.1 - 1.1e-08 34.9 0.2 2.9e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EMD65688.1 - 0.00057 19.4 1.6 0.63 9.9 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD65688.1 - 0.012 15.2 0.9 0.34 10.7 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMD65688.1 - 0.068 13.1 0.9 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD65688.1 - 0.22 11.2 1.9 1.5 8.5 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD65688.1 - 2.5 8.2 5.4 1.2 9.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 EMD65689.1 - 1.3e-54 183.9 0.0 1.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD65689.1 - 4.2e-15 56.2 0.0 5.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD65689.1 - 3.1e-09 36.3 0.0 4.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMD65689.1 - 0.00013 21.2 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMD65689.1 - 0.00033 19.9 0.0 0.00059 19.0 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMD65689.1 - 0.012 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EMD65689.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 EMD65689.1 - 0.055 13.1 0.0 0.075 12.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EMD65689.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Mac PF12464.3 EMD65690.1 - 7.8e-20 70.6 0.0 1.7e-19 69.5 0.0 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.19 EMD65690.1 - 4.3e-10 38.6 5.0 3.9e-07 29.2 1.9 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD65690.1 - 1.3e-09 37.4 5.2 2.8e-06 26.7 1.9 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribosomal_S27e PF01667.12 EMD65691.1 - 6.1e-29 99.3 6.8 7.9e-29 98.9 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMD65691.1 - 0.0066 16.2 1.4 0.0075 16.1 1.0 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EMD65691.1 - 0.025 14.0 0.8 0.044 13.2 0.5 1.4 1 0 0 1 1 1 0 CSL zinc finger DeoC PF01791.4 EMD65692.1 - 6e-39 133.7 1.7 6.1e-19 68.2 0.0 2.1 1 1 1 2 2 2 2 DeoC/LacD family aldolase His_biosynth PF00977.16 EMD65692.1 - 0.03 13.5 0.1 0.072 12.3 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Ribosomal_S4 PF00163.14 EMD65693.1 - 3.8e-29 100.9 0.7 7.5e-29 99.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EMD65693.1 - 5.9e-13 48.0 0.8 5.9e-13 48.0 0.6 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 EMD65694.1 - 3e-41 139.2 3.9 3e-41 139.2 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Nexin_C PF08628.7 EMD65694.1 - 0.06 13.4 0.1 0.084 12.9 0.1 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal PAS_9 PF13426.1 EMD65695.1 - 4.6e-16 59.0 0.0 2e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EMD65695.1 - 0.027 14.2 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 PAS fold MukE PF04288.8 EMD65695.1 - 0.049 12.4 0.1 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 MukE-like family Acetyltransf_1 PF00583.19 EMD65696.1 - 4.5e-11 42.6 0.0 6.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMD65696.1 - 2.2e-06 27.3 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMD65696.1 - 6e-05 23.1 0.0 9.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD65696.1 - 0.0029 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD65696.1 - 0.027 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_28 PF13518.1 EMD65696.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_8 PF13523.1 EMD65696.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EMD65698.1 - 7.9e-24 84.0 45.2 3.7e-12 45.6 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SNARE PF05739.14 EMD65701.1 - 2.7e-18 65.4 1.1 2.7e-18 65.4 0.8 3.3 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EMD65701.1 - 2e-17 63.2 0.5 2e-17 63.2 0.3 3.3 3 1 0 3 3 3 1 Syntaxin Surfac_D-trimer PF09006.6 EMD65701.1 - 0.021 14.5 0.5 0.31 10.7 0.1 2.8 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Syntaxin-18_N PF10496.4 EMD65701.1 - 0.024 14.4 3.3 0.032 14.0 0.5 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 EMD65701.1 - 0.034 14.4 4.4 1.2 9.4 1.0 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EMD65701.1 - 0.059 13.5 5.6 4.9 7.3 0.1 3.4 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 EMD65701.1 - 0.084 12.4 0.3 0.084 12.4 0.2 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.6 EMD65701.1 - 0.13 12.1 16.6 1.6 8.4 0.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAUS5 PF14817.1 EMD65701.1 - 2.5 6.5 19.6 10 4.5 9.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 zf-C2H2 PF00096.21 EMD65703.1 - 4.7e-31 105.2 56.6 9.1e-06 25.7 0.7 10.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD65703.1 - 4.6e-27 92.3 55.5 0.00027 21.0 0.5 10.3 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD65703.1 - 1.4e-15 56.6 55.6 3.9e-05 23.7 0.6 12.0 11 1 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD65703.1 - 7.7e-07 29.0 24.7 0.57 10.3 0.0 8.6 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD65703.1 - 2.4e-06 27.5 23.3 0.71 10.1 0.4 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type DUF2064 PF09837.4 EMD65703.1 - 0.065 12.8 0.2 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) ROS_MUCR PF05443.6 EMD65703.1 - 1.1 9.0 5.0 25 4.6 0.0 3.5 4 1 0 4 4 4 0 ROS/MUCR transcriptional regulator protein zf-C2H2_6 PF13912.1 EMD65703.1 - 3.5 7.6 26.1 4.3 7.3 1.6 6.9 6 1 0 6 6 6 0 C2H2-type zinc finger RNA_pol_Rpb6 PF01192.17 EMD65704.1 - 3.7e-21 74.6 0.6 8.6e-21 73.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Esterase PF00756.15 EMD65705.1 - 3.6e-55 187.1 0.1 4.4e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMD65705.1 - 1.7e-06 27.3 0.1 3.2e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD65705.1 - 2e-06 27.6 0.0 2.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD65705.1 - 0.00077 19.4 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD65705.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EMD65705.1 - 0.0037 16.8 0.1 0.13 11.8 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMD65705.1 - 0.0055 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMD65705.1 - 0.0065 16.0 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase_phd PF10503.4 EMD65705.1 - 0.0077 15.5 0.0 0.05 12.8 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 EMD65705.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 EMD65705.1 - 0.046 12.2 0.0 0.068 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 EMD65705.1 - 0.13 11.0 0.0 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Xpo1 PF08389.7 EMD65706.1 - 6.7e-36 123.4 1.4 4.2e-34 117.5 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EMD65706.1 - 0.002 18.0 0.4 46 4.4 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat FWWh PF14922.1 EMD65706.1 - 0.043 13.3 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function IBN_N PF03810.14 EMD65706.1 - 0.085 12.7 4.0 0.22 11.4 0.0 3.5 3 1 1 4 4 4 0 Importin-beta N-terminal domain ATP_transf PF09830.4 EMD65707.1 - 3.4e-18 65.1 0.0 5.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.1 EMD65708.1 - 0.00098 19.2 0.2 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Clathrin_bdg PF15045.1 EMD65708.1 - 0.069 12.6 0.2 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DSBA PF01323.15 EMD65709.1 - 9.3e-23 80.7 0.0 1.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Cnd3 PF12719.2 EMD65709.1 - 0.08 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain adh_short PF00106.20 EMD65710.1 - 6e-21 75.0 0.0 8.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD65710.1 - 2.3e-06 27.3 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EMD65710.1 - 0.065 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EMD65710.1 - 0.14 11.2 0.0 6.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Anticodon_1 PF08264.8 EMD65711.1 - 0.02 14.6 0.5 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA MIF4G PF02854.14 EMD65713.1 - 2.3e-26 92.5 0.5 3.7e-26 91.8 0.4 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EMD65713.1 - 5.3e-23 80.8 0.0 1.4e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Ribosomal_L4 PF00573.17 EMD65713.1 - 1.6 8.0 14.9 11 5.3 4.7 3.0 1 1 1 2 2 2 0 Ribosomal protein L4/L1 family DPM2 PF07297.7 EMD65714.1 - 1.8e-36 124.2 3.8 2.1e-36 124.0 2.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EMD65714.1 - 7e-06 25.6 1.1 7.8e-06 25.5 0.8 1.1 1 0 0 1 1 1 1 PIG-P DUF4083 PF13314.1 EMD65714.1 - 0.024 14.4 0.3 0.024 14.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4229 PF14012.1 EMD65714.1 - 0.034 14.0 0.3 0.034 14.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Permease PF02405.11 EMD65714.1 - 0.067 12.6 0.1 0.067 12.6 0.1 1.6 2 0 0 2 2 2 0 Permease COX14 PF14880.1 EMD65714.1 - 0.071 12.7 4.6 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MrpF_PhaF PF04066.8 EMD65714.1 - 0.22 11.8 0.4 0.22 11.8 0.3 1.9 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF1469 PF07332.6 EMD65714.1 - 1.3 8.7 3.8 2 8.1 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) PspC PF04024.7 EMD65714.1 - 2.2 7.8 6.2 6.6 6.2 0.3 2.2 2 0 0 2 2 2 0 PspC domain WD40 PF00400.27 EMD65715.1 - 3.9e-22 77.2 12.1 1.1e-07 31.4 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIA PF03153.8 EMD65715.1 - 0.39 10.5 18.4 0.064 13.1 9.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EMD65715.1 - 2 6.2 21.1 3.4 5.4 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMD65715.1 - 7.5 4.4 16.8 0.27 9.2 7.4 1.6 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 EMD65715.1 - 7.7 4.8 19.3 17 3.7 13.4 1.5 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_18 PF00704.23 EMD65716.1 - 6.4e-09 35.7 0.7 1.3e-08 34.6 0.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EMD65717.1 - 4.8e-29 101.1 33.6 4.8e-29 101.1 23.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Spc7 PF08317.6 EMD65718.1 - 4.3e-96 321.4 8.9 4.3e-96 321.4 6.2 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_N PF15402.1 EMD65718.1 - 2.6e-86 290.5 75.5 1.7e-66 224.9 21.5 4.7 1 1 2 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.1 EMD65718.1 - 7.5e-09 35.1 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 MDM31_MDM32 PF08118.6 EMD65718.1 - 2.6 6.3 2.9 1.2 7.5 0.1 1.6 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins tRNA-synt_2 PF00152.15 EMD65722.1 - 1e-110 369.6 0.0 1.4e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMD65722.1 - 0.00011 21.8 1.2 0.00029 20.4 0.8 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EMD65722.1 - 0.0057 15.8 0.1 0.018 14.2 0.1 1.8 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) LRR_4 PF12799.2 EMD65723.1 - 0.0022 17.5 0.4 0.61 9.7 0.0 3.6 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) UbiA PF01040.13 EMD65725.1 - 4.1e-31 108.1 19.5 5.7e-31 107.6 13.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Abhydrolase_6 PF12697.2 EMD65726.1 - 3.4e-25 89.2 0.1 7.1e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65726.1 - 3.5e-12 46.2 0.0 3e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD65726.1 - 1.4e-10 41.1 0.0 1.4e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMD65726.1 - 3.7e-05 23.4 0.0 9.6e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMD65726.1 - 0.00029 20.1 0.0 0.056 12.7 0.0 2.6 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 EMD65726.1 - 0.024 14.3 0.0 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GYD PF08734.6 EMD65726.1 - 0.036 13.8 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 GYD domain Lipase_3 PF01764.20 EMD65726.1 - 0.04 13.5 0.1 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PAP2 PF01569.16 EMD65727.1 - 7.6e-25 87.0 0.3 7.6e-25 87.0 0.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PQ-loop PF04193.9 EMD65728.1 - 4.2e-22 77.4 6.3 2.8e-13 49.1 1.4 2.6 2 0 0 2 2 2 2 PQ loop repeat ERG4_ERG24 PF01222.12 EMD65729.1 - 2.8e-133 444.6 26.4 3.4e-133 444.3 18.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Acyl-CoA_dh_1 PF00441.19 EMD65730.1 - 1.4e-41 142.0 0.7 2.2e-41 141.4 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD65730.1 - 5.9e-21 73.7 0.2 1.1e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EMD65730.1 - 1.9e-18 65.9 0.3 3.6e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EMD65730.1 - 1.4e-16 61.0 0.0 2.9e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD65730.1 - 5.1e-08 33.2 0.0 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.12 EMD65730.1 - 0.15 12.1 0.5 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 C6 domain 2OG-FeII_Oxy PF03171.15 EMD65731.1 - 9.7e-14 51.4 0.1 1.5e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD65731.1 - 4.4e-10 40.1 0.0 7.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Memo PF01875.12 EMD65731.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Memo-like protein TFR_dimer PF04253.10 EMD65732.1 - 8.2e-17 60.9 0.0 1.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMD65732.1 - 1.1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMD65732.1 - 0.0006 19.3 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.17 EMD65732.1 - 0.0047 16.5 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 PA domain MARVEL PF01284.18 EMD65733.1 - 1.3e-26 93.1 5.1 1.7e-26 92.7 3.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Methyltransf_31 PF13847.1 EMD65734.1 - 5.7e-31 107.1 0.0 8.2e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD65734.1 - 7.6e-21 74.4 0.0 1.8e-20 73.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD65734.1 - 4.8e-19 69.0 0.0 8.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD65734.1 - 1.2e-17 64.0 0.0 2.7e-17 62.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD65734.1 - 4.3e-16 59.1 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD65734.1 - 5.1e-12 46.0 0.0 1.2e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD65734.1 - 2.2e-11 43.3 0.0 3.5e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMD65734.1 - 5.1e-11 42.2 0.0 9.3e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EMD65734.1 - 2.2e-07 30.1 0.0 4.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EMD65734.1 - 4.2e-07 30.0 0.0 1.4e-06 28.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMD65734.1 - 1.2e-05 24.2 0.0 1.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EMD65734.1 - 4.7e-05 23.0 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EMD65734.1 - 9.5e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EMD65734.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD65734.1 - 0.00021 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EMD65734.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EMD65734.1 - 0.0029 16.6 0.0 0.004 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EMD65734.1 - 0.0056 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.9 EMD65734.1 - 0.0072 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.13 EMD65734.1 - 0.0086 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Nol1_Nop2_Fmu PF01189.12 EMD65734.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 NOL1/NOP2/sun family DUF938 PF06080.7 EMD65734.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.10 EMD65734.1 - 0.045 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.14 EMD65734.1 - 0.046 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase FmrO PF07091.6 EMD65734.1 - 0.047 12.6 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) DUF2404 PF10296.4 EMD65736.1 - 3.6e-30 103.9 0.1 6.3e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EMD65736.1 - 0.024 14.8 0.2 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 PH domain MoaE PF02391.12 EMD65737.1 - 6.3e-30 103.3 0.0 8.2e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein TLD PF07534.11 EMD65738.1 - 2.7e-27 95.4 0.0 9.3e-27 93.7 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EMD65738.1 - 4.5e-13 49.2 0.1 8.9e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal Ribosomal_L36 PF00444.13 EMD65739.1 - 1.7e-16 59.8 11.9 2.5e-16 59.3 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Tropomyosin_1 PF12718.2 EMD65740.1 - 2.5e-05 24.1 18.2 0.00049 19.9 8.9 3.1 2 1 0 2 2 2 1 Tropomyosin like Spectrin PF00435.16 EMD65740.1 - 0.00028 21.1 16.7 0.074 13.3 1.2 3.2 2 1 1 3 3 3 2 Spectrin repeat HALZ PF02183.13 EMD65740.1 - 0.0023 17.5 7.2 0.58 9.9 0.1 3.6 2 1 1 3 3 3 1 Homeobox associated leucine zipper CALCOCO1 PF07888.6 EMD65740.1 - 0.0067 14.7 11.3 0.031 12.5 4.9 2.1 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like AKNA PF12443.3 EMD65740.1 - 0.0072 16.3 0.1 0.0072 16.3 0.1 2.7 2 1 0 2 2 2 1 AT-hook-containing transcription factor ADIP PF11559.3 EMD65740.1 - 0.0075 16.1 21.9 0.014 15.2 6.8 2.7 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EMD65740.1 - 0.0086 15.8 19.4 0.017 14.8 9.3 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EMD65740.1 - 0.009 15.6 24.8 0.068 12.7 0.4 2.7 1 1 0 2 2 2 1 IncA protein Laminin_I PF06008.9 EMD65740.1 - 0.012 14.9 12.4 0.12 11.6 4.2 2.3 2 0 0 2 2 2 0 Laminin Domain I EB1_binding PF05937.6 EMD65740.1 - 0.012 15.9 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 EB-1 Binding Domain Phage_GPD PF05954.6 EMD65740.1 - 0.012 14.8 2.4 0.015 14.4 1.4 1.4 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) CENP-F_leu_zip PF10473.4 EMD65740.1 - 0.015 15.1 20.3 0.24 11.2 7.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 EMD65740.1 - 0.016 15.5 14.3 0.069 13.4 0.1 3.3 3 0 0 3 3 3 0 Striatin family Occludin_ELL PF07303.8 EMD65740.1 - 0.019 15.7 8.7 0.42 11.3 0.0 3.1 2 1 1 3 3 3 0 Occludin homology domain Lebercilin PF15619.1 EMD65740.1 - 0.024 14.0 23.5 1.1 8.6 3.4 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease APG6 PF04111.7 EMD65740.1 - 0.028 13.4 15.7 0.48 9.4 8.7 2.3 2 1 0 2 2 2 0 Autophagy protein Apg6 Taxilin PF09728.4 EMD65740.1 - 0.031 13.3 14.5 0.023 13.7 3.9 2.7 2 1 0 2 2 2 0 Myosin-like coiled-coil protein Mod_r PF07200.8 EMD65740.1 - 0.038 13.9 2.1 0.038 13.9 1.4 3.0 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ArsR PF09824.4 EMD65740.1 - 0.057 12.7 1.5 0.65 9.2 0.2 2.2 1 1 0 2 2 2 0 ArsR transcriptional regulator ATG16 PF08614.6 EMD65740.1 - 0.072 12.9 21.7 0.27 11.0 6.1 2.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CASP_C PF08172.7 EMD65740.1 - 0.072 12.1 12.0 0.048 12.6 1.9 2.3 1 1 0 2 2 2 0 CASP C terminal DUF724 PF05266.9 EMD65740.1 - 0.095 12.3 13.7 1.5 8.4 3.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Sec34 PF04136.10 EMD65740.1 - 0.1 12.2 5.5 1.7 8.2 1.3 2.3 2 0 0 2 2 2 0 Sec34-like family GAS PF13851.1 EMD65740.1 - 0.11 11.6 15.8 4.5 6.4 0.0 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EMD65740.1 - 0.18 10.2 13.0 0.2 10.1 5.2 2.1 2 0 0 2 2 2 0 AAA domain DivIVA PF05103.8 EMD65740.1 - 0.26 11.3 16.3 3.3 7.7 0.3 3.0 2 1 0 2 2 2 0 DivIVA protein ERM PF00769.14 EMD65740.1 - 0.28 10.6 18.3 1.2 8.5 9.3 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF1192 PF06698.6 EMD65740.1 - 0.38 10.5 6.3 0.81 9.5 0.1 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) DUF4201 PF13870.1 EMD65740.1 - 0.43 9.9 16.4 0.13 11.7 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TBPIP PF07106.8 EMD65740.1 - 0.43 10.1 15.9 2.9 7.4 0.1 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 EMD65740.1 - 0.45 9.9 21.7 0.33 10.3 0.4 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF904 PF06005.7 EMD65740.1 - 0.46 10.8 0.1 0.46 10.8 0.1 3.4 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF2721 PF11026.3 EMD65740.1 - 0.52 9.9 4.3 1.3 8.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SipA PF09052.5 EMD65740.1 - 0.52 8.6 8.5 0.043 12.2 1.6 1.9 2 0 0 2 2 2 0 Salmonella invasion protein A TMF_DNA_bd PF12329.3 EMD65740.1 - 0.59 9.9 18.2 2.3 8.1 0.4 3.8 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Ead_Ea22 PF13935.1 EMD65740.1 - 0.63 10.3 5.8 1.5 9.1 4.0 1.7 1 1 0 1 1 1 0 Ead/Ea22-like protein Cep57_MT_bd PF06657.8 EMD65740.1 - 0.66 9.9 12.2 0.53 10.2 0.9 3.8 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 zf-C4H2 PF10146.4 EMD65740.1 - 0.72 9.8 7.9 1.3 8.9 5.5 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein CENP-Q PF13094.1 EMD65740.1 - 0.81 9.6 19.0 8.4 6.3 0.1 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Vps51 PF08700.6 EMD65740.1 - 0.83 9.5 9.2 2.8 7.8 0.1 3.8 3 1 1 4 4 4 0 Vps51/Vps67 TMF_TATA_bd PF12325.3 EMD65740.1 - 0.87 9.3 20.8 9.7 5.9 0.5 3.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.1 EMD65740.1 - 0.9 8.4 16.0 3.6 6.4 6.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.5 EMD65740.1 - 0.95 9.5 5.0 1.5 8.9 0.2 3.1 1 1 2 3 3 3 0 Osmosensory transporter coiled coil Surfac_D-trimer PF09006.6 EMD65740.1 - 1.2 8.8 4.1 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Tropomyosin PF00261.15 EMD65740.1 - 1.2 8.1 17.9 10 5.1 0.2 2.7 2 1 0 2 2 2 0 Tropomyosin DUF4200 PF13863.1 EMD65740.1 - 1.3 9.0 18.9 8.1 6.4 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.7 EMD65740.1 - 1.3 8.7 14.5 0.88 9.3 0.2 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EMD65740.1 - 1.4 8.4 18.1 0.78 9.2 0.2 4.0 2 2 2 4 4 4 0 Septum formation initiator Spc7 PF08317.6 EMD65740.1 - 1.7 7.2 15.4 0.56 8.8 5.0 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 EMD65740.1 - 2.1 8.1 20.4 0.8 9.4 0.6 3.9 3 1 1 4 4 4 0 Prefoldin subunit DUF342 PF03961.8 EMD65740.1 - 2.1 6.6 12.4 1.2 7.4 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2968 PF11180.3 EMD65740.1 - 4.1 6.7 20.3 0.074 12.4 5.6 2.8 3 1 0 3 3 2 0 Protein of unknown function (DUF2968) Cep57_CLD_2 PF14197.1 EMD65740.1 - 4.7 7.2 19.6 4.1 7.4 1.9 3.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 HR1 PF02185.11 EMD65740.1 - 5.2 6.8 18.2 0.29 10.9 0.8 4.4 4 2 1 5 5 4 0 Hr1 repeat HalX PF08663.5 EMD65740.1 - 5.8 6.9 10.1 0.66 9.9 2.1 2.9 3 0 0 3 3 3 0 HalX domain PspB PF06667.7 EMD65740.1 - 5.9 6.8 8.9 5.8 6.9 0.0 3.8 3 2 1 4 4 4 0 Phage shock protein B DUF1664 PF07889.7 EMD65740.1 - 6.2 6.6 10.2 4.5 7.0 2.1 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EMD65740.1 - 7 6.7 17.4 7 6.7 0.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EMD65740.1 - 10 6.4 13.4 44 4.4 0.5 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Glucosamine_iso PF01182.15 EMD65742.1 - 5.8e-58 195.8 0.0 6.8e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SR-25 PF10500.4 EMD65743.1 - 0.93 8.9 6.6 1.2 8.5 4.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apolipoprotein PF01442.13 EMD65746.1 - 0.064 12.7 1.0 0.079 12.4 0.7 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cep57_MT_bd PF06657.8 EMD65746.1 - 0.097 12.6 2.8 0.13 12.2 2.0 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 FliP PF00813.15 EMD65746.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 FliP family HALZ PF02183.13 EMD65746.1 - 0.29 10.8 1.9 0.43 10.3 1.2 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper Pex16 PF08610.5 EMD65747.1 - 0.2 10.6 5.0 0.29 10.0 3.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) HEAT_PBS PF03130.11 EMD65749.1 - 0.43 11.1 0.1 0.43 11.1 0.1 2.2 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat DUF3431 PF11913.3 EMD65750.1 - 1.6e-83 279.6 0.2 2e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Gly_reductase PF09338.6 EMD65750.1 - 0.15 10.2 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits RRM_1 PF00076.17 EMD65751.1 - 7.6e-20 70.3 0.0 1.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD65751.1 - 3.3e-16 58.9 0.0 4.7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD65751.1 - 3.7e-12 45.9 0.0 5.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 EMD65752.1 - 7.8e-32 109.5 10.9 7.8e-32 109.5 7.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMD65752.1 - 5.2e-26 90.6 9.0 5.2e-26 90.6 6.3 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMD65752.1 - 7.3e-23 81.5 0.1 7.3e-23 81.5 0.0 2.3 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMD65752.1 - 1.4e-14 53.1 1.9 1.4e-14 53.1 1.3 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EMD65752.1 - 8.6e-08 31.7 9.2 8.6e-08 31.7 6.4 2.7 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EMD65752.1 - 8.2 6.2 21.8 2.4 7.9 4.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EMD65752.1 - 9.1 6.3 24.4 0.89 9.6 6.8 2.8 2 1 0 2 2 2 0 RING-like domain F-box-like PF12937.2 EMD65753.1 - 0.00024 20.7 0.2 0.00058 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EMD65753.1 - 0.0065 16.4 10.0 0.62 10.2 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 EMD65753.1 - 0.01 15.4 12.8 9.9 5.9 0.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) FCH PF00611.18 EMD65753.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain LRR_1 PF00560.28 EMD65753.1 - 2.6 8.4 10.9 30 5.1 0.3 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat zf-CCHC PF00098.18 EMD65754.1 - 3.7e-08 32.9 2.6 5.5e-08 32.3 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EMD65754.1 - 0.045 13.2 0.3 0.085 12.3 0.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger AflR PF08493.5 EMD65754.1 - 1.8 7.4 4.5 2 7.3 3.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Nnf1 PF03980.9 EMD65755.1 - 2.5e-30 104.6 1.7 3.7e-30 104.1 0.2 1.8 2 0 0 2 2 2 1 Nnf1 DUF892 PF05974.7 EMD65755.1 - 0.0014 18.4 2.7 0.0029 17.4 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF892) CR6_interact PF10147.4 EMD65755.1 - 0.014 14.6 0.8 2.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GAS PF13851.1 EMD65755.1 - 0.026 13.7 1.0 0.048 12.8 0.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 EMD65755.1 - 0.032 14.5 6.0 0.89 9.9 2.5 2.6 2 0 0 2 2 2 0 SlyX Cytochrom_B562 PF07361.6 EMD65755.1 - 0.13 12.6 1.7 0.31 11.4 0.7 1.9 2 0 0 2 2 2 0 Cytochrome b562 Nsp1_C PF05064.8 EMD65755.1 - 0.21 11.2 3.0 0.24 11.0 1.0 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region Pox_A_type_inc PF04508.7 EMD65755.1 - 7.9 6.5 9.0 5.3 7.0 0.5 3.3 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat NAD_binding_2 PF03446.10 EMD65756.1 - 5.8e-35 120.5 0.1 1e-34 119.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD65756.1 - 4.4e-32 110.7 0.4 5.5e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 EMD65756.1 - 0.00012 21.7 0.1 0.00028 20.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMD65756.1 - 0.003 17.9 0.0 0.0085 16.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EMD65756.1 - 0.078 12.9 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 EMD65756.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EMD65756.1 - 0.11 11.9 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pil1 PF13805.1 EMD65758.1 - 6.8e-150 497.6 0.5 9.9e-150 497.1 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Tom37_C PF11801.3 EMD65758.1 - 5.7e-24 84.8 0.0 5.7e-24 84.8 0.0 3.2 4 1 0 4 4 4 1 Tom37 C-terminal domain Tom37 PF10568.4 EMD65758.1 - 2.9e-18 65.8 0.0 7.2e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EMD65758.1 - 2.6e-07 30.4 0.6 6.3e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD65758.1 - 0.0012 19.3 0.4 0.0087 16.5 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain FAM92 PF06730.6 EMD65758.1 - 0.045 13.0 2.5 0.055 12.7 0.8 1.6 1 1 0 1 1 1 0 FAM92 protein GFO_IDH_MocA PF01408.17 EMD65760.1 - 3e-13 50.3 0.1 4.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_S28 PF05577.7 EMD65761.1 - 9.7e-44 149.6 1.0 2.3e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Neurexophilin PF06312.7 EMD65761.1 - 0.00062 19.0 0.1 0.0016 17.7 0.0 1.6 2 0 0 2 2 2 1 Neurexophilin HET PF06985.6 EMD65762.1 - 1.7e-24 86.5 1.7 1.2e-23 83.7 1.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EMD65763.1 - 2.5e-06 27.5 0.6 2.4e-05 24.3 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65763.1 - 0.00018 21.3 0.0 0.0057 16.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EMD65764.1 - 0.009 16.9 0.0 0.015 16.1 0.0 1.4 1 1 0 1 1 1 1 EthD domain VirArc_Nuclease PF12187.3 EMD65764.1 - 0.029 13.7 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Viral/Archaeal nuclease DUF1330 PF07045.6 EMD65764.1 - 0.11 12.3 0.1 0.33 10.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) Cellulase PF00150.13 EMD65765.1 - 4.6e-39 134.2 3.6 4.6e-39 134.2 2.5 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EMD65765.1 - 2.2e-24 85.0 5.4 4.5e-22 77.6 3.0 3.0 3 0 0 3 3 3 2 Carbohydrate binding domain X2 RRM_6 PF14259.1 EMD65766.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.15 EMD65767.1 - 4.4e-14 51.8 0.0 5.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 EMD65768.1 - 4.4e-28 96.1 18.1 2e-07 30.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EMD65768.1 - 0.00072 19.7 0.2 2.9 8.2 0.0 3.1 2 0 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 EMD65768.1 - 0.001 17.4 0.4 0.24 9.6 0.0 3.5 3 1 1 4 4 4 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EMD65768.1 - 0.036 12.8 0.0 2.1 7.0 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like ING PF12998.2 EMD65769.1 - 0.0018 18.5 10.5 0.33 11.2 3.3 3.3 3 1 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding APG6 PF04111.7 EMD65769.1 - 0.0057 15.7 11.1 0.017 14.1 7.7 1.8 1 0 0 1 1 1 1 Autophagy protein Apg6 GTPase_Cys_C PF12631.2 EMD65769.1 - 0.25 11.7 6.0 2.9 8.3 0.1 3.8 4 1 0 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE AAA_13 PF13166.1 EMD65769.1 - 0.69 8.3 8.5 0.34 9.3 4.2 1.6 2 0 0 2 2 2 0 AAA domain Bap31 PF05529.7 EMD65769.1 - 0.69 9.3 6.2 0.98 8.8 3.5 1.9 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 EMD65769.1 - 1.2 6.8 5.2 0.54 8.0 2.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EMD65769.1 - 1.9 8.7 6.7 1.7 8.9 0.2 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 EMD65769.1 - 4.7 4.6 6.3 2.2 5.7 2.7 1.5 2 0 0 2 2 2 0 Prominin Med4 PF10018.4 EMD65769.1 - 5 6.4 16.4 0.44 9.9 3.6 3.7 3 1 1 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 HAUS6_N PF14661.1 EMD65769.1 - 5.8 6.1 10.5 5 6.3 4.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.9 EMD65769.1 - 6.2 6.7 19.2 0.029 14.3 5.1 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) AbiH PF14253.1 EMD65769.1 - 7.1 6.1 6.9 3.3 7.2 1.9 2.0 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Seryl_tRNA_N PF02403.17 EMD65769.1 - 7.7 6.5 20.2 2.8 8.0 8.0 3.8 3 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_S5 PF00333.15 EMD65770.1 - 1.7e-28 98.1 2.4 1.7e-28 98.1 1.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMD65770.1 - 6.3e-22 76.6 0.1 1.2e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 EMD65770.1 - 9.8 6.7 13.9 0.54 10.7 6.0 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Aldedh PF00171.17 EMD65771.1 - 3.5e-165 549.8 0.4 3.9e-165 549.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD65771.1 - 0.026 13.7 0.0 0.077 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) AAA PF00004.24 EMD65772.1 - 8.5e-48 161.8 0.0 1.6e-41 141.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD65772.1 - 4.7e-08 33.2 0.5 2.6e-06 27.5 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EMD65772.1 - 3.5e-07 29.8 0.0 3.9e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMD65772.1 - 1.3e-05 25.2 0.0 3.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EMD65772.1 - 4.7e-05 23.2 0.0 0.00016 21.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EMD65772.1 - 0.00015 21.8 0.1 0.0026 17.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMD65772.1 - 0.00019 21.1 0.0 0.00082 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD65772.1 - 0.00098 18.5 0.0 0.0042 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMD65772.1 - 0.0012 18.9 0.0 0.0053 16.9 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.1 EMD65772.1 - 0.0015 18.4 0.0 0.0054 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD65772.1 - 0.0018 18.1 0.1 0.018 14.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EMD65772.1 - 0.0032 18.2 0.0 0.026 15.3 0.0 2.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD65772.1 - 0.0037 16.9 0.2 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EMD65772.1 - 0.0059 16.9 0.1 0.052 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EMD65772.1 - 0.008 16.2 0.0 0.047 13.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 EMD65772.1 - 0.012 14.3 0.4 0.021 13.5 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 EMD65772.1 - 0.013 15.8 0.0 0.053 13.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EMD65772.1 - 0.022 14.6 0.0 0.069 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMD65772.1 - 0.026 13.7 0.8 0.056 12.5 0.0 1.9 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EMD65772.1 - 0.027 14.1 0.1 0.08 12.5 0.1 1.9 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EMD65772.1 - 0.038 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RuvB_N PF05496.7 EMD65772.1 - 0.053 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EMD65772.1 - 0.054 12.7 0.1 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EMD65772.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Tetraspannin PF00335.15 EMD65773.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2248 PF10005.4 EMD65774.1 - 0.054 12.4 0.1 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) Cyclin_N PF00134.18 EMD65777.1 - 2.9e-37 127.0 0.6 5.3e-37 126.2 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMD65777.1 - 3.3e-11 43.1 1.6 6.5e-11 42.1 0.3 2.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain WD40 PF00400.27 EMD65778.1 - 4.1e-12 45.4 0.0 0.27 11.1 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EMD65778.1 - 0.0026 17.2 0.2 0.11 12.0 0.1 3.3 2 1 0 2 2 2 1 PQQ-like domain SUR7 PF06687.7 EMD65779.1 - 8.3e-35 120.2 1.2 1e-34 120.0 0.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rad4 PF03835.10 EMD65780.1 - 1.6e-14 53.5 4.9 1.9e-14 53.2 2.6 1.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EMD65780.1 - 7.5e-13 48.6 2.1 7.5e-13 48.6 1.4 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Na_H_Exchanger PF00999.16 EMD65781.1 - 4.8e-68 229.4 42.4 6.9e-68 228.9 29.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SNARE PF05739.14 EMD65783.1 - 2.2e-13 49.6 10.0 1.1e-12 47.3 4.7 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMD65783.1 - 3e-05 24.1 3.3 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 1 Syntaxin Tweety PF04906.8 EMD65783.1 - 0.00062 18.3 1.5 0.001 17.5 1.1 1.3 1 0 0 1 1 1 1 Tweety DUF805 PF05656.9 EMD65783.1 - 0.023 14.5 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) RPW8 PF05659.6 EMD65783.1 - 0.032 13.7 0.5 0.071 12.6 0.2 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.4 EMD65783.1 - 0.046 13.8 1.5 0.28 11.3 0.5 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 EMD65783.1 - 0.068 12.7 4.1 0.11 11.9 2.3 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3753 PF12575.3 EMD65783.1 - 0.089 12.6 2.6 0.17 11.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Phage_GP20 PF06810.6 EMD65783.1 - 0.092 12.1 3.1 0.11 11.8 1.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 IFT46_B_C PF12317.3 EMD65783.1 - 0.15 11.4 1.5 0.38 10.0 0.7 1.8 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Baculo_PEP_C PF04513.7 EMD65783.1 - 0.16 11.8 3.7 14 5.4 1.1 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 EMD65783.1 - 0.19 12.5 1.7 37 5.1 0.3 2.9 2 1 1 3 3 3 0 Occludin homology domain PilJ PF13675.1 EMD65783.1 - 0.31 11.3 6.6 3.5 7.9 1.3 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term OppC_N PF12911.2 EMD65783.1 - 0.38 10.1 2.6 0.67 9.3 1.8 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C XH PF03469.9 EMD65783.1 - 0.51 9.9 3.6 0.57 9.8 1.0 1.9 1 1 1 2 2 2 0 XH domain Sec2p PF06428.6 EMD65783.1 - 0.7 9.7 4.7 20 5.0 1.9 2.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.7 EMD65783.1 - 0.74 10.1 5.9 31 4.9 0.0 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EMD65783.1 - 1.1 9.1 4.0 5.8 6.7 1.3 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3904 PF13044.1 EMD65783.1 - 1.2 7.4 4.3 1.8 6.8 2.6 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3904) DUF948 PF06103.6 EMD65783.1 - 2.2 8.1 12.2 0.1 12.4 0.9 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.10 EMD65783.1 - 2.7 8.2 9.6 8.4 6.6 2.4 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Abhydrolase_9_N PF15420.1 EMD65784.1 - 0.00045 20.0 7.5 0.00054 19.7 5.2 1.0 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus DUF1614 PF07758.6 EMD65784.1 - 6.6 6.4 7.8 1.2 8.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) NAPRTase PF04095.11 EMD65785.1 - 1.2e-51 175.4 0.5 2.5e-28 98.9 0.1 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Cyt-b5 PF00173.23 EMD65786.1 - 6.7e-17 61.0 0.0 1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.19 EMD65787.1 - 1.6e-81 274.2 17.8 2e-81 273.8 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65787.1 - 2.2e-32 112.1 13.5 2.2e-32 112.1 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PC_rep PF01851.17 EMD65789.1 - 1.9e-40 134.8 19.9 5.3e-09 35.8 0.0 9.9 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMD65789.1 - 8.9e-18 64.3 1.1 3.4e-12 46.4 0.0 4.9 4 1 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 EMD65789.1 - 1.9e-07 31.3 2.5 7.7e-05 23.0 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat HEAT PF02985.17 EMD65789.1 - 6.2e-06 25.8 1.5 11 6.4 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat DUF1546 PF07571.8 EMD65789.1 - 0.089 12.9 0.0 17 5.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) mRNA_triPase PF02940.10 EMD65790.1 - 2e-44 151.9 0.0 2.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PK PF00224.16 EMD65791.1 - 5.5e-171 567.8 3.6 6.7e-171 567.5 2.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EMD65791.1 - 4.9e-30 103.4 0.0 1.7e-29 101.7 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EMD65791.1 - 0.00073 18.4 0.5 0.0018 17.2 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EMD65791.1 - 0.016 14.1 0.1 0.075 11.9 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 EMD65792.1 - 9.1e-31 105.3 0.0 1e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FHA PF00498.21 EMD65793.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF3336 PF11815.3 EMD65795.1 - 2.3e-40 137.4 0.7 4e-40 136.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMD65795.1 - 3.1e-24 86.0 0.2 7.6e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase AT_hook PF02178.14 EMD65796.1 - 0.012 15.1 1.1 0.012 15.1 0.8 2.9 2 0 0 2 2 2 0 AT hook motif PUF PF00806.14 EMD65809.1 - 0.04 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Mo-co_dimer PF03404.11 EMD65810.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain UbiA PF01040.13 EMD65812.1 - 1.7e-14 53.6 6.7 1.7e-14 53.6 4.6 2.0 1 1 1 2 2 2 1 UbiA prenyltransferase family ATP_synt_H PF05493.8 EMD65812.1 - 0.016 15.2 2.8 0.057 13.4 1.9 2.1 1 1 0 1 1 1 0 ATP synthase subunit H 2TM PF13239.1 EMD65812.1 - 1.5 8.9 5.1 2.5 8.1 1.3 2.3 2 0 0 2 2 2 0 2TM domain DUF2282 PF10048.4 EMD65813.1 - 0.031 14.1 0.4 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) BNR PF02012.15 EMD65813.1 - 0.36 10.8 0.4 0.36 10.8 0.2 3.0 4 0 0 4 4 4 0 BNR/Asp-box repeat RTC_insert PF05189.8 EMD65814.1 - 0.11 12.4 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF221 PF02714.10 EMD65816.1 - 5.5e-75 252.2 22.5 6.7e-75 251.9 15.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EMD65816.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein BTB PF00651.26 EMD65817.1 - 6e-07 29.4 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3723 PF12520.3 EMD65819.1 - 7.1e-52 176.5 0.0 1.1e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Death PF00531.17 EMD65819.1 - 0.0084 15.8 0.4 0.83 9.4 0.1 2.5 2 0 0 2 2 2 2 Death domain Patatin PF01734.17 EMD65820.1 - 0.067 13.1 0.8 0.16 11.8 0.1 2.1 2 1 0 2 2 2 0 Patatin-like phospholipase GrpE PF01025.14 EMD65821.1 - 0.0002 20.9 1.0 0.00028 20.4 0.7 1.1 1 0 0 1 1 1 1 GrpE Spectrin PF00435.16 EMD65821.1 - 0.0068 16.6 1.8 0.0098 16.1 1.3 1.2 1 0 0 1 1 1 1 Spectrin repeat Spc7 PF08317.6 EMD65821.1 - 0.012 14.2 0.3 0.018 13.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Apolipoprotein PF01442.13 EMD65821.1 - 0.026 14.0 1.8 0.033 13.6 1.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2422 PF10337.4 EMD65821.1 - 0.028 13.2 0.1 0.033 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Allexi_40kDa PF05549.6 EMD65821.1 - 0.045 13.0 1.3 0.061 12.6 0.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Nup54 PF13874.1 EMD65821.1 - 0.099 12.3 1.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 COG2 PF06148.6 EMD65821.1 - 0.1 12.4 0.5 0.16 11.8 0.3 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EMD65821.1 - 0.15 11.9 0.8 0.24 11.2 0.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.5 EMD65821.1 - 0.16 11.9 1.2 0.37 10.7 0.8 1.8 1 1 0 1 1 1 0 HalX domain ATG16 PF08614.6 EMD65821.1 - 0.36 10.6 5.8 0.062 13.1 1.7 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 EMD65821.1 - 0.44 10.9 2.5 0.31 11.4 0.5 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CUT PF02376.10 EMD65822.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 1 1 0 1 1 1 0 CUT domain DivIVA PF05103.8 EMD65822.1 - 0.013 15.5 1.7 0.013 15.5 1.2 2.4 2 0 0 2 2 2 0 DivIVA protein DUF3644 PF12358.3 EMD65822.1 - 0.031 14.5 0.2 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) DUF3289 PF11692.3 EMD65822.1 - 0.082 12.1 1.3 0.11 11.6 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3289) Laminin_II PF06009.7 EMD65822.1 - 0.17 11.6 7.7 0.13 11.9 0.4 2.4 2 1 0 2 2 2 0 Laminin Domain II LMBR1 PF04791.11 EMD65822.1 - 0.17 10.4 3.5 0.14 10.6 1.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein LRAT PF04970.8 EMD65822.1 - 0.28 11.1 2.0 0.24 11.3 0.2 1.7 2 0 0 2 2 2 0 Lecithin retinol acyltransferase IncA PF04156.9 EMD65822.1 - 0.31 10.6 21.4 0.35 10.4 1.8 2.1 1 1 0 2 2 2 0 IncA protein UPF0449 PF15136.1 EMD65822.1 - 0.38 10.9 6.0 5 7.4 2.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF2450 PF10475.4 EMD65822.1 - 0.56 9.0 11.2 1 8.1 6.9 1.7 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) GrpE PF01025.14 EMD65822.1 - 0.6 9.6 12.6 1.9 8.0 3.1 2.2 1 1 1 2 2 2 0 GrpE Retrotrans_gag PF03732.12 EMD65822.1 - 0.67 10.0 3.6 5.8 7.0 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.3 EMD65822.1 - 0.77 9.6 11.0 0.23 11.3 1.0 3.0 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EMD65822.1 - 0.95 8.8 14.9 0.37 10.2 3.0 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.10 EMD65822.1 - 1.3 8.6 12.0 0.78 9.2 1.1 2.8 2 1 1 3 3 3 0 Septum formation initiator TBPIP PF07106.8 EMD65822.1 - 1.7 8.1 10.7 0.14 11.7 1.0 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ERM PF00769.14 EMD65822.1 - 1.8 8.0 16.2 2 7.9 1.8 2.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EMD65822.1 - 2.2 8.6 9.7 1 9.6 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4110 PF13422.1 EMD65822.1 - 6.3 6.7 7.4 1.2 9.0 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) DUF2205 PF10224.4 EMD65822.1 - 7.4 6.2 11.0 0.4 10.2 1.1 2.6 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) AIG1 PF04548.11 EMD65824.1 - 0.0095 15.0 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 AIG1 family NAD_binding_6 PF08030.7 EMD65825.1 - 6.1e-08 32.7 0.0 1.6e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD65825.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain TPR_14 PF13428.1 EMD65826.1 - 3.4e-07 30.3 0.8 0.0041 17.6 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD65826.1 - 8.8e-06 25.1 0.6 0.037 13.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD65826.1 - 3.9e-05 23.9 0.2 0.013 15.8 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD65826.1 - 7e-05 22.6 0.1 0.024 14.5 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.2 EMD65826.1 - 0.00014 21.5 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_6 PF13174.1 EMD65826.1 - 0.0062 16.9 0.4 0.49 10.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EMD65826.1 - 0.0072 16.4 0.1 1.4 9.0 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD65826.1 - 0.017 15.0 1.3 1.7 8.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD65826.1 - 0.018 15.1 0.1 0.35 11.0 0.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 EMD65826.1 - 0.021 14.4 0.0 2.7 7.6 0.0 2.5 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_1 PF00515.23 EMD65826.1 - 0.03 13.9 0.1 1.5 8.5 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD65826.1 - 0.033 14.8 0.9 0.23 12.1 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF309 PF03745.9 EMD65826.1 - 0.055 12.9 1.4 1.9 7.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF309) TPR_9 PF13371.1 EMD65826.1 - 0.056 13.3 0.4 0.45 10.4 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD65826.1 - 0.058 13.1 0.3 3.1 7.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Trans_reg_C PF00486.23 EMD65826.1 - 0.12 12.2 0.4 2.5 8.0 0.0 3.0 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal DUF1996 PF09362.5 EMD65827.1 - 3.4e-38 131.6 0.0 6.6e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DDE_3 PF13358.1 EMD65828.1 - 8.8e-09 35.2 0.5 2.8e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Imm35 PF15581.1 EMD65828.1 - 0.062 13.3 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 35 DUF3788 PF12663.2 EMD65828.1 - 0.071 12.8 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) zf-C2H2 PF00096.21 EMD65832.1 - 0.00016 21.7 4.8 0.0017 18.5 0.6 4.8 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMD65832.1 - 0.0013 18.8 4.4 1.4 9.0 0.2 3.4 1 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EMD65832.1 - 0.0071 16.2 0.8 0.059 13.3 0.1 2.5 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMD65832.1 - 0.011 15.6 1.0 0.011 15.6 0.7 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EMD65832.1 - 0.14 12.4 4.9 2.8 8.2 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMD65832.1 - 0.74 10.2 13.3 2.5 8.5 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD65832.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMD65832.1 - 2 8.5 6.5 3.1 7.9 0.1 3.1 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EMD65832.1 - 5.1 7.6 20.6 2.1 8.8 0.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger APH PF01636.18 EMD65833.1 - 2e-13 50.6 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD65833.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EMD65833.1 - 0.0054 15.9 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 EMD65833.1 - 0.056 12.2 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 EMD65833.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TMCO5 PF14992.1 EMD65834.1 - 0.12 11.4 2.3 0.15 11.1 1.6 1.1 1 0 0 1 1 1 0 TMCO5 family Pup PF05639.6 EMD65834.1 - 0.77 10.2 3.1 0.38 11.2 0.6 1.7 2 0 0 2 2 2 0 Pup-like protein SERTA PF06031.8 EMD65835.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 SERTA motif DUF1612 PF07756.7 EMD65835.1 - 0.062 13.4 0.1 0.075 13.1 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1612) HLH PF00010.21 EMD65836.1 - 4.2e-11 42.3 0.0 8.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TauD PF02668.11 EMD65837.1 - 4.2e-17 62.6 0.0 6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 EMD65839.1 - 1.4e-12 47.0 0.7 4e-12 45.5 0.5 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD65839.1 - 2.4e-07 30.5 14.2 4.8e-07 29.5 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CheY-binding PF09078.6 EMD65839.1 - 0.091 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 CheY binding Endosulfine PF04667.12 EMD65840.1 - 1.4e-12 47.3 0.2 2.6e-12 46.5 0.1 1.6 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Tubulin PF00091.20 EMD65841.1 - 8.6e-70 234.9 0.0 1.9e-69 233.7 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMD65841.1 - 6.4e-49 165.1 0.2 1.1e-48 164.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMD65841.1 - 1.4e-05 25.1 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMD65841.1 - 0.0085 15.5 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain HLH PF00010.21 EMD65844.1 - 1.7e-11 43.6 0.0 3.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HSP20 PF00011.16 EMD65845.1 - 3.2e-08 33.3 0.0 4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family HLH PF00010.21 EMD65846.1 - 1.2e-10 40.9 0.1 2.6e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain XFP_N PF09364.5 EMD65848.1 - 9e-180 597.1 0.0 1.2e-179 596.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EMD65848.1 - 8.6e-86 286.5 0.0 1.2e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EMD65848.1 - 2.1e-84 281.5 0.0 3.9e-84 280.6 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase p450 PF00067.17 EMD65849.1 - 1.4e-20 73.2 0.0 7.4e-18 64.3 0.0 2.6 2 1 1 3 3 3 2 Cytochrome P450 HSP20 PF00011.16 EMD65850.1 - 2.4e-06 27.3 0.0 0.00024 20.9 0.0 2.2 2 1 0 2 2 2 2 Hsp20/alpha crystallin family Transaldolase PF00923.14 EMD65851.1 - 4.3e-74 249.2 0.1 2.7e-73 246.6 0.0 1.8 1 1 0 1 1 1 1 Transaldolase Ecl1 PF12855.2 EMD65852.1 - 2.8e-12 45.7 0.7 6.1e-12 44.6 0.5 1.6 1 0 0 1 1 1 1 Life-span regulatory factor HTH_Tnp_Tc5 PF03221.11 EMD65853.1 - 2.3e-08 33.7 0.0 6e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD65853.1 - 1.5e-06 27.6 0.6 3e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 EMD65853.1 - 0.006 15.9 0.1 0.36 10.2 0.0 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 EMD65853.1 - 0.016 15.2 0.1 0.071 13.1 0.1 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain BrkDBD PF09607.5 EMD65853.1 - 0.019 14.5 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain APO_RNA-bind PF05634.6 EMD65853.1 - 0.13 11.4 0.1 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding DDE_1 PF03184.14 EMD65854.1 - 1.2e-30 106.3 0.0 1.3e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD65854.1 - 3e-05 23.7 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF972 PF06156.8 EMD65855.1 - 0.00044 20.5 0.8 0.00084 19.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF2458 PF10454.4 EMD65855.1 - 0.0045 16.8 1.6 0.0058 16.5 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) zf-C4H2 PF10146.4 EMD65855.1 - 0.0058 16.6 1.4 0.0074 16.3 1.0 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein BAR_2 PF10455.4 EMD65855.1 - 0.014 14.3 0.9 0.019 13.9 0.6 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ATG16 PF08614.6 EMD65855.1 - 0.024 14.4 1.0 0.024 14.4 0.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 EMD65855.1 - 0.029 14.2 5.4 0.059 13.2 3.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlgN PF05130.7 EMD65855.1 - 0.077 13.2 7.3 0.073 13.3 3.9 1.8 1 1 1 2 2 2 0 FlgN protein DUF848 PF05852.6 EMD65855.1 - 0.09 12.6 5.0 0.17 11.7 3.4 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF904 PF06005.7 EMD65855.1 - 0.12 12.7 6.8 1.2 9.4 4.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Cauli_AT PF03233.8 EMD65855.1 - 0.13 11.9 3.1 0.21 11.3 2.1 1.3 1 0 0 1 1 1 0 Aphid transmission protein APG6 PF04111.7 EMD65855.1 - 0.17 10.9 4.8 0.23 10.4 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HrpB7 PF09486.5 EMD65855.1 - 0.17 11.7 6.0 0.96 9.3 2.7 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) V_ATPase_I PF01496.14 EMD65855.1 - 0.26 9.1 1.2 0.28 8.9 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 EMD65855.1 - 0.27 10.2 3.7 0.38 9.7 2.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 EMD65855.1 - 0.6 10.2 8.1 0.88 9.6 3.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EMD65855.1 - 1.3 8.8 4.4 2.1 8.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EMD65855.1 - 2.2 7.8 8.6 1.9 8.0 0.8 2.5 1 1 1 2 2 2 0 Septum formation initiator TPR_12 PF13424.1 EMD65856.1 - 4.7e-42 141.8 14.7 2.3e-13 49.8 0.2 4.3 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMD65856.1 - 1.1e-37 126.8 2.4 9.6e-10 38.0 0.1 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMD65856.1 - 2e-10 39.6 0.3 0.4 10.6 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD65856.1 - 6.3e-09 35.0 1.7 0.14 11.7 0.6 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD65856.1 - 6.7e-08 32.1 1.1 0.34 11.2 0.2 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD65856.1 - 0.00034 20.2 3.4 0.11 12.1 1.8 3.2 1 1 3 4 4 4 2 TPR repeat Apc3 PF12895.2 EMD65856.1 - 0.00058 19.9 6.0 0.69 10.0 0.6 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMD65856.1 - 0.0021 18.6 0.2 2.2 9.0 0.0 3.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD65856.1 - 0.0047 16.7 5.8 12 6.1 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD65856.1 - 0.0074 15.9 0.3 9.7 6.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DALR_2 PF09190.6 EMD65856.1 - 0.085 13.1 0.5 2.6 8.3 0.2 2.6 1 1 1 2 2 2 0 DALR domain Rab5-bind PF09311.6 EMD65856.1 - 0.12 12.2 2.4 0.33 10.8 0.3 2.4 1 1 2 3 3 3 0 Rabaptin-like protein DDE_1 PF03184.14 EMD65857.1 - 1.2e-11 44.1 0.0 1.3e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box PF00505.14 EMD65858.1 - 3.4e-13 49.6 0.0 8.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMD65858.1 - 9e-10 38.7 0.0 2.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EMD65858.1 - 5.3e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EMD65858.1 - 3.9e-05 23.4 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EMD65859.1 - 5.7e-05 22.3 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3435 PF11917.3 EMD65860.1 - 1.4e-73 248.0 0.0 2.1e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) BTB PF00651.26 EMD65862.1 - 2.3e-11 43.6 0.2 3.8e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Maelstrom PF13017.1 EMD65862.1 - 0.052 13.0 0.1 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 piRNA pathway germ-plasm component SPDY PF03771.11 EMD65864.1 - 0.15 11.5 0.5 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF317) DUF2232 PF09991.4 EMD65864.1 - 0.3 10.0 8.2 0.32 9.9 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Asp_Glu_race PF01177.17 EMD65864.1 - 5.1 6.9 6.3 16 5.3 4.4 1.8 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase DUF4231 PF14015.1 EMD65864.1 - 8.4 6.4 8.6 13 5.8 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) zf-C2H2 PF00096.21 EMD65865.1 - 3.6e-13 48.9 40.7 0.0088 16.3 0.9 8.9 7 2 1 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD65865.1 - 5.2e-09 35.7 40.8 0.062 13.6 0.1 8.5 7 2 1 8 8 8 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMD65865.1 - 2.5e-05 24.3 29.8 0.095 12.8 0.2 5.9 2 1 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMD65865.1 - 3e-05 24.0 27.5 0.17 12.1 0.2 7.8 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD65865.1 - 5e-05 23.0 0.4 5e-05 23.0 0.3 8.3 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD65865.1 - 9.1e-05 22.4 38.8 0.063 13.4 0.6 7.7 8 2 0 8 8 8 3 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 EMD65865.1 - 1.1 8.8 0.0 1.1 8.8 0.0 5.2 5 1 0 5 5 5 0 A2L zinc ribbon domain Thioredoxin_2 PF13098.1 EMD65865.1 - 6.2 7.0 6.6 20 5.4 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like domain Ank_2 PF12796.2 EMD65866.1 - 1.4e-57 192.0 7.9 1.5e-18 66.8 0.1 2.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMD65866.1 - 5.4e-28 95.3 5.6 1.7e-06 27.5 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EMD65866.1 - 6.5e-26 90.2 2.9 7.1e-11 42.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD65866.1 - 1.4e-19 68.1 0.2 0.0061 16.6 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMD65866.1 - 1.9e-13 50.1 3.4 0.00016 21.7 0.1 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF1843 PF08898.5 EMD65866.1 - 0.087 12.8 0.7 0.087 12.8 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Death PF00531.17 EMD65866.1 - 0.16 11.7 1.6 11 5.9 0.1 2.4 1 1 0 2 2 2 0 Death domain DUF3521 PF12035.3 EMD65866.1 - 3 7.7 4.7 22 5.0 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3521) DUF937 PF06078.6 EMD65866.1 - 4.4 7.5 9.3 0.95 9.6 2.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) DUF3435 PF11917.3 EMD65867.1 - 2.2e-147 491.1 0.1 3e-147 490.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-RING_2 PF13639.1 EMD65868.1 - 2.2e-13 49.8 5.3 3.9e-13 49.0 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EMD65868.1 - 2.1e-09 36.9 0.0 9.9e-09 34.8 0.0 2.0 2 0 0 2 2 2 1 PA domain zf-rbx1 PF12678.2 EMD65868.1 - 3.9e-09 36.4 1.1 8e-09 35.4 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD65868.1 - 5.2e-09 35.9 5.0 8.4e-09 35.3 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD65868.1 - 1.2e-08 34.4 2.6 2.1e-08 33.6 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD65868.1 - 3.1e-08 33.1 3.0 4.6e-08 32.6 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD65868.1 - 1.8e-07 30.7 2.1 2.8e-07 30.1 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMD65868.1 - 0.00096 18.9 0.6 0.0018 18.0 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMD65868.1 - 0.055 13.2 0.9 0.081 12.6 0.2 1.7 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EMD65868.1 - 0.14 12.1 2.5 0.35 10.8 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EMD65868.1 - 0.18 11.8 3.2 0.36 10.9 2.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EMD65868.1 - 0.2 11.5 4.1 0.42 10.5 2.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EMD65868.1 - 0.87 9.2 2.5 1.7 8.2 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PNRC PF15365.1 EMD65869.1 - 2.3 8.3 6.1 8.9 6.4 0.2 2.4 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator WD40 PF00400.27 EMD65870.1 - 2.2e-38 128.7 2.8 2.6e-07 30.2 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD65870.1 - 1.5e-08 34.6 1.3 0.0058 16.3 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 EMD65871.1 - 4.1e-167 556.0 0.0 5e-167 555.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EMD65871.1 - 0.015 14.0 0.0 6.4 5.4 0.0 3.2 2 1 1 3 3 3 0 M42 glutamyl aminopeptidase Hydrolase_6 PF13344.1 EMD65872.1 - 3.3e-30 103.9 0.0 6.3e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD65872.1 - 6e-12 46.4 0.0 1.2e-11 45.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD65872.1 - 9.6e-11 41.2 0.0 2.2e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EMD65872.1 - 3.6e-08 33.8 0.1 2.4e-05 24.6 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DNA_primase_lrg PF04104.9 EMD65873.1 - 5.5e-82 274.9 0.0 1.2e-81 273.8 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit F_bP_aldolase PF01116.15 EMD65874.1 - 9.1e-80 267.8 0.3 1e-79 267.6 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Raffinose_syn PF05691.7 EMD65874.1 - 0.11 10.0 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 MIP PF00230.15 EMD65875.1 - 5e-54 183.1 17.4 6.5e-54 182.7 12.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein MutS_V PF00488.16 EMD65876.1 - 9.8e-81 270.6 0.0 1.6e-80 269.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMD65876.1 - 7.1e-53 179.4 0.2 1.5e-52 178.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMD65876.1 - 2.9e-33 114.2 0.1 1.2e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EMD65876.1 - 1.3e-14 54.4 0.0 3.6e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EMD65876.1 - 3e-11 43.3 0.3 6.8e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EMD65876.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EMD65876.1 - 0.017 15.4 2.4 0.026 14.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EMD65876.1 - 0.086 12.7 0.6 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myosin_tail_1 PF01576.14 EMD65876.1 - 0.64 7.6 4.9 1.4 6.5 1.1 2.3 2 1 0 2 2 2 0 Myosin tail ORC6 PF05460.8 EMD65877.1 - 0.0017 17.5 1.6 0.0021 17.1 1.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) GerE PF00196.14 EMD65877.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family PIG-U PF06728.8 EMD65878.1 - 2.8e-116 388.5 30.3 3.2e-116 388.3 21.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EMD65879.1 - 7.4e-115 383.0 0.0 7.4e-115 383.0 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EMD65879.1 - 1.7e-09 37.6 0.0 4.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Mnd1 PF03962.10 EMD65879.1 - 3.9 7.1 17.5 7.9 6.0 12.1 1.5 1 0 0 1 1 1 0 Mnd1 family TPR_20 PF14561.1 EMD65879.1 - 4.1 7.6 12.4 2.2 8.4 3.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 EMD65880.1 - 1e-24 86.9 23.5 1e-24 86.9 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD65880.1 - 0.0019 16.4 0.5 0.0029 15.8 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RL11D PF11088.3 EMD65881.1 - 0.16 11.8 0.4 5.7 6.8 0.1 2.6 3 0 0 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Zip PF02535.17 EMD65882.1 - 1.8e-53 181.5 1.5 2.3e-53 181.2 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Mur_ligase_M PF08245.7 EMD65883.1 - 5.6e-08 33.0 1.5 6.8e-07 29.5 0.3 2.7 2 1 0 2 2 2 1 Mur ligase middle domain DUF2122 PF09895.4 EMD65883.1 - 0.06 13.5 0.2 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) HTH_Tnp_Tc3_2 PF01498.13 EMD65885.1 - 6.7e-22 77.3 0.0 1.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EMD65885.1 - 2.5e-07 30.8 1.6 1e-06 28.8 0.1 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EMD65885.1 - 2.1e-06 28.4 2.5 0.0011 19.7 0.0 2.4 2 1 0 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.1 EMD65885.1 - 2.1e-06 27.1 0.1 0.00016 21.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EMD65885.1 - 0.0001 21.3 1.3 0.15 11.2 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EMD65885.1 - 0.00043 20.2 0.0 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 HTH-like domain HTH_33 PF13592.1 EMD65885.1 - 0.0051 16.3 0.1 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EMD65885.1 - 0.045 12.5 0.0 0.12 11.1 0.0 1.6 1 1 1 2 2 2 0 Rhodopirellula transposase DDE domain UB2H PF14814.1 EMD65885.1 - 0.053 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain Sigma70_r4_2 PF08281.7 EMD65885.1 - 0.064 12.7 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 FKBP_C PF00254.23 EMD65886.1 - 8.5e-32 109.0 0.0 1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase E1-E2_ATPase PF00122.15 EMD65888.1 - 1.3e-55 187.9 6.0 1.3e-55 187.9 4.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD65888.1 - 4.7e-42 143.5 6.9 4.7e-42 143.5 4.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD65888.1 - 2.3e-29 103.3 0.0 6.3e-29 101.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD65888.1 - 6.8e-16 57.9 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD65888.1 - 9.2e-14 52.0 0.0 2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD65888.1 - 9.8e-12 44.1 0.0 7.6e-10 38.1 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD65888.1 - 1.4e-06 28.0 0.2 5.4e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fer2_3 PF13085.1 EMD65890.1 - 0.17 11.7 4.6 0.32 10.8 3.2 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-B_box PF00643.19 EMD65890.1 - 0.87 9.5 11.6 0.73 9.7 4.7 2.7 2 1 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.11 EMD65890.1 - 1.1 9.1 6.5 0.86 9.5 2.5 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Memo PF01875.12 EMD65891.1 - 8.6e-70 234.7 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein UvrD_C PF13361.1 EMD65892.1 - 8.9e-73 245.7 0.0 2.1e-72 244.4 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EMD65892.1 - 2.3e-63 214.4 4.5 3.9e-62 210.3 1.2 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EMD65892.1 - 2.5e-14 53.2 0.0 3e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EMD65892.1 - 3.7e-12 45.8 0.1 2.5e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMD65892.1 - 1.6e-06 27.8 0.0 0.00019 21.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMD65892.1 - 0.00016 21.3 2.0 0.0016 18.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF416 PF04222.7 EMD65892.1 - 0.026 13.6 2.0 0.029 13.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Cellulase PF00150.13 EMD65893.1 - 5.5e-11 42.1 4.4 2.7e-10 39.9 3.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRAM_rpt PF07016.6 EMD65893.1 - 0.074 12.3 0.4 0.074 12.3 0.3 1.6 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor MutL PF13941.1 EMD65893.1 - 0.17 10.1 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Glyco_transf_28 PF03033.15 EMD65894.1 - 3.9e-20 72.0 0.0 8.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMD65894.1 - 3.9e-05 22.4 0.0 6.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMD65894.1 - 0.00047 19.8 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Metallophos PF00149.23 EMD65896.1 - 6.9e-41 139.8 0.2 9e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF605 PF04652.11 EMD65896.1 - 6.5 6.0 12.6 9.2 5.5 8.7 1.2 1 0 0 1 1 1 0 Vta1 like Aldedh PF00171.17 EMD65898.1 - 3.9e-182 605.6 0.5 4.5e-182 605.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD65898.1 - 0.03 13.5 0.0 0.99 8.5 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Methyltransf_PK PF05891.7 EMD65899.1 - 7e-80 267.4 0.0 8.1e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EMD65899.1 - 0.0023 17.6 0.0 0.024 14.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD65899.1 - 0.0059 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.2 EMD65899.1 - 0.065 13.5 0.0 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 DinB superfamily Methyltransf_11 PF08241.7 EMD65899.1 - 0.07 13.6 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Med8 PF10232.4 EMD65900.1 - 0.0073 15.8 9.0 1.4 8.3 0.1 3.0 2 1 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 Nop14 PF04147.7 EMD65900.1 - 0.13 10.2 19.8 0.19 9.6 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 EMD65900.1 - 0.24 11.0 9.9 0.44 10.1 2.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Prothymosin PF03247.9 EMD65900.1 - 1.1 9.4 35.1 3.2 7.9 16.9 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 EMD65900.1 - 8 5.9 23.1 4.3 6.8 1.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin Adaptin_binding PF10199.4 EMD65900.1 - 9.9 6.4 17.8 36 4.6 12.3 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Methyltransf_11 PF08241.7 EMD65901.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DNA_binding_1 PF01035.15 EMD65902.1 - 5.5e-27 93.3 0.0 6.9e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TPR_11 PF13414.1 EMD65903.1 - 9.7e-07 28.3 9.9 0.0027 17.3 0.7 4.6 1 1 3 4 4 4 3 TPR repeat TPR_17 PF13431.1 EMD65903.1 - 2e-06 27.5 2.3 0.076 13.2 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD65903.1 - 0.0016 18.3 10.2 0.024 14.5 0.8 4.6 5 2 0 5 5 5 2 Tetratricopeptide repeat SPO22 PF08631.5 EMD65903.1 - 0.0021 17.1 0.3 0.004 16.2 0.2 1.5 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.1 EMD65903.1 - 0.095 13.3 0.4 0.095 13.3 0.3 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD65903.1 - 0.22 11.1 3.0 19 5.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMD65903.1 - 2.1 9.1 16.2 0.31 11.7 2.7 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Ribophorin_II PF05817.9 EMD65904.1 - 2.5e-27 95.3 0.0 3.1e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II MscS_TM PF12794.2 EMD65904.1 - 0.0082 14.7 1.3 0.19 10.2 0.1 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel inner membrane domain 1 bZIP_2 PF07716.10 EMD65905.1 - 0.0077 16.0 8.7 0.019 14.7 6.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper E6 PF00518.12 EMD65907.1 - 0.069 13.4 0.3 0.083 13.2 0.2 1.1 1 0 0 1 1 1 0 Early Protein (E6) DUF1746 PF08508.5 EMD65909.1 - 1e-37 128.6 0.1 1.5e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HIG_1_N PF04588.8 EMD65910.1 - 1.6e-20 72.5 0.2 2.2e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region LEA_4 PF02987.11 EMD65910.1 - 0.0006 19.6 4.6 0.0014 18.4 3.2 1.7 1 0 0 1 1 1 1 Late embryogenesis abundant protein VirB3 PF05101.8 EMD65910.1 - 0.14 12.1 0.3 0.51 10.3 0.0 1.9 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein TPX2 PF06886.6 EMD65910.1 - 0.35 10.9 14.6 0.47 10.5 9.1 2.0 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF2262 PF10020.4 EMD65910.1 - 2.6 8.2 8.2 4.3 7.5 5.2 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) SGL PF08450.7 EMD65911.1 - 2.4e-68 230.2 0.0 2.7e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EMD65911.1 - 0.15 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Albumin_I PF08027.6 EMD65912.1 - 0.029 14.1 1.2 0.035 13.8 0.8 1.2 1 0 0 1 1 1 0 Albumin I Fer2_2 PF01799.15 EMD65912.1 - 0.059 13.2 3.6 1.5 8.7 2.9 2.1 1 1 1 2 2 2 0 [2Fe-2S] binding domain ET PF01684.11 EMD65912.1 - 0.14 12.2 4.3 0.22 11.6 3.0 1.4 1 1 0 1 1 1 0 ET module BolA PF01722.13 EMD65913.1 - 3.8e-30 103.6 1.1 4.5e-30 103.4 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.23 EMD65914.1 - 1.8e-68 230.8 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD65914.1 - 4.4e-11 43.5 0.1 9.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Grp1_Fun34_YaaH PF01184.14 EMD65915.1 - 4.8e-84 280.8 16.6 5.8e-84 280.5 11.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family AAA PF00004.24 EMD65916.1 - 8.9e-17 61.5 0.0 1.8e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD65916.1 - 0.0045 17.1 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EMD65916.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMD65916.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain FAA_hydrolase PF01557.13 EMD65917.1 - 6.8e-43 146.6 0.0 9.5e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMD65917.1 - 9.9e-19 67.3 0.0 2.1e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal QueC PF06508.8 EMD65917.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Cupin_2 PF07883.6 EMD65918.1 - 1.7e-08 33.8 0.0 3.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMD65918.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EMD65918.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EMD65918.1 - 0.066 12.8 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin Peptidase_S15 PF02129.13 EMD65919.1 - 3e-40 138.3 0.3 4.3e-40 137.8 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMD65919.1 - 1.8e-38 132.6 0.6 2.7e-38 132.0 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMD65919.1 - 0.0011 18.9 0.1 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD65919.1 - 0.002 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LigB PF02900.13 EMD65920.1 - 7.8e-13 48.0 0.0 9.3e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase zf-C2H2 PF00096.21 EMD65921.1 - 4.5e-08 32.9 14.6 0.00011 22.3 2.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD65921.1 - 3.1e-07 30.2 16.6 0.00016 21.8 0.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD65921.1 - 2.7e-06 27.4 1.5 2.7e-06 27.4 1.0 3.6 3 1 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 EMD65921.1 - 7.7e-06 25.7 11.8 7.7e-06 25.7 8.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.7 EMD65921.1 - 0.00064 19.7 1.8 0.00064 19.7 1.2 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMD65921.1 - 0.011 15.9 0.7 2.2 8.5 0.0 2.9 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EMD65921.1 - 0.022 14.4 0.7 0.022 14.4 0.5 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.2 EMD65921.1 - 0.029 14.5 6.1 0.35 11.1 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD65921.1 - 1.2 9.0 10.2 3.6 7.6 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger HypA PF01155.14 EMD65921.1 - 7.6 6.2 11.7 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 EMD65922.1 - 3e-26 91.9 31.3 3e-26 91.9 21.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD65922.1 - 4.6e-11 41.9 5.3 4.6e-11 41.9 3.7 2.5 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EMD65922.1 - 5.8e-06 24.7 2.4 5.8e-06 24.7 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aldedh PF00171.17 EMD65923.1 - 2.7e-11 42.4 0.0 5.4e-09 34.8 0.0 2.2 1 1 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 EMD65925.1 - 3.3e-21 75.7 0.0 8.7e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 EMD65925.1 - 8.5e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 EMD65925.1 - 1.5e-09 37.2 0.6 1.5e-06 27.3 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMD65925.1 - 7.1e-06 26.0 0.1 5.7e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD65925.1 - 1.1e-05 25.3 0.2 2.6e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMD65925.1 - 0.00037 20.6 0.0 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD65925.1 - 0.00046 19.1 0.8 0.00079 18.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD65925.1 - 0.014 15.7 0.2 0.13 12.6 0.1 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD65925.1 - 0.037 13.1 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EMD65925.1 - 0.039 12.8 1.2 0.09 11.6 0.8 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMD65925.1 - 0.084 11.7 0.1 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EMD65925.1 - 0.14 10.6 0.2 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EMD65925.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMD65925.1 - 0.18 11.4 0.1 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prominin PF05478.6 EMD65926.1 - 0.062 10.8 0.4 0.081 10.4 0.3 1.1 1 0 0 1 1 1 0 Prominin CcdA PF07362.7 EMD65926.1 - 0.082 12.7 1.0 8.8 6.2 0.3 2.4 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA EF-hand_6 PF13405.1 EMD65928.1 - 1.7e-11 43.0 1.9 3.7e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EMD65928.1 - 1.7e-09 36.3 2.1 6.4e-05 21.9 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMD65928.1 - 1.9e-09 37.4 4.2 3.2e-07 30.3 0.4 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMD65928.1 - 1.7e-07 30.2 5.8 2e-05 23.6 0.9 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMD65928.1 - 1.2e-06 27.9 1.2 0.0045 16.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EMD65928.1 - 6.5e-05 22.7 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Afi1 PF07792.7 EMD65929.1 - 3.8e-62 208.5 0.1 2.9e-61 205.7 0.0 2.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EMD65929.1 - 9.4e-38 128.4 0.0 2.6e-37 126.9 0.0 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 EMD65929.1 - 1.3e-07 30.4 0.0 0.1 11.0 0.0 4.3 4 1 1 5 5 5 3 Transport protein Avl9 DUF2347 PF09804.4 EMD65929.1 - 0.0024 17.1 0.0 0.019 14.2 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SET PF00856.23 EMD65929.1 - 0.074 13.3 0.6 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 SET domain Daxx PF03344.10 EMD65929.1 - 0.64 8.4 15.9 1 7.7 11.0 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EMD65929.1 - 8.7 4.1 18.3 0.51 8.2 8.9 1.5 2 0 0 2 2 2 0 Nop14-like family HeLo PF14479.1 EMD65930.1 - 1.3e-26 93.7 0.4 1.4e-26 93.5 0.3 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Peptidase_M16 PF00675.15 EMD65931.1 - 0.066 12.9 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) ArabFuran-catal PF09206.6 EMD65932.1 - 8.1e-165 547.5 18.3 1.1e-164 547.1 12.7 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EMD65932.1 - 2e-61 205.8 1.4 3.2e-61 205.2 1.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Mitofilin PF09731.4 EMD65933.1 - 1.3e-137 459.9 33.2 1.1e-120 404.0 21.6 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF479 PF04336.7 EMD65933.1 - 1.1 9.4 5.5 1.6 8.9 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function, DUF479 DUF1515 PF07439.6 EMD65933.1 - 1.4 8.8 5.9 0.53 10.1 0.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DUF2756 PF10956.3 EMD65933.1 - 4.6 7.5 11.5 5.6 7.2 2.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2756) Syja_N PF02383.13 EMD65935.1 - 3.1e-92 308.7 0.0 3.9e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain 7TMR-DISM_7TM PF07695.6 EMD65935.1 - 0.079 12.6 3.2 0.12 11.9 2.2 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Ras PF00071.17 EMD65936.1 - 2.6e-59 199.2 0.3 3e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD65936.1 - 2.3e-19 70.0 0.0 4.1e-19 69.2 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EMD65936.1 - 4e-15 55.4 0.0 5e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD65936.1 - 6.3e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD65936.1 - 3.6e-07 29.5 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD65936.1 - 4e-06 26.7 0.0 6.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMD65936.1 - 0.014 15.5 0.1 1.2 9.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain Shikimate_DH PF01488.15 EMD65936.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF258 PF03193.11 EMD65936.1 - 0.023 13.9 0.2 0.12 11.5 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD65936.1 - 0.037 14.0 0.5 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain Amidase02_C PF12123.3 EMD65936.1 - 0.071 12.7 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAT PF03417.11 EMD65936.1 - 0.08 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SRPRB PF09439.5 EMD65936.1 - 0.1 11.8 0.1 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EMD65936.1 - 0.13 12.1 0.1 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pro-kuma_activ PF09286.6 EMD65937.1 - 6.3e-43 146.2 0.1 1.1e-42 145.4 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMD65937.1 - 1.6e-11 43.9 0.8 3.8e-11 42.6 0.0 1.7 1 1 1 2 2 2 1 Subtilase family Na_Ca_ex PF01699.19 EMD65938.1 - 6e-26 90.7 20.7 1.8e-16 60.0 4.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EMD65938.1 - 0.036 13.9 0.6 0.036 13.9 0.4 2.9 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) DUF443 PF04276.7 EMD65938.1 - 6.5 6.1 10.8 0.14 11.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Asp_Glu_race PF01177.17 EMD65939.1 - 5.9e-27 94.9 1.2 3.3e-26 92.5 0.3 2.2 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EMD65939.1 - 7.4e-25 87.3 0.0 1.4e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aldo_ket_red PF00248.16 EMD65941.1 - 3.2e-56 190.2 0.0 3.6e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_10 PF13673.1 EMD65942.1 - 1e-05 25.6 0.0 7.2e-05 22.8 0.0 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD65942.1 - 3.5e-05 23.7 0.1 6.1e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD65942.1 - 0.00031 20.8 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fringe PF02434.11 EMD65943.1 - 3.7e-08 32.8 0.4 1.8e-07 30.6 0.3 1.9 1 1 0 1 1 1 1 Fringe-like PAN_3 PF08277.7 EMD65943.1 - 0.0017 17.9 0.3 0.0034 16.9 0.2 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_2 PF08276.6 EMD65943.1 - 0.0092 15.8 1.2 0.02 14.7 0.8 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.1 EMD65943.1 - 0.018 14.7 0.3 0.052 13.2 0.2 1.7 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.16 EMD65943.1 - 0.02 14.4 0.0 0.084 12.4 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase SPT16 PF08644.6 EMD65944.1 - 2.6e-56 189.7 0.2 2.6e-56 189.7 0.1 3.2 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EMD65944.1 - 2.1e-47 160.7 0.5 2.1e-47 160.7 0.3 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EMD65944.1 - 8.9e-24 84.2 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EMD65944.1 - 2.7e-22 78.5 0.1 9.5e-22 76.7 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EMD65945.1 - 2.8e-15 55.8 5.3 7e-13 48.1 0.1 3.5 4 1 0 4 4 4 2 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.14 EMD65946.1 - 5.2e-45 152.7 0.1 1.2e-43 148.3 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD65946.1 - 1e-05 24.9 0.0 2.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD65946.1 - 0.04 13.7 0.0 0.089 12.6 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMD65946.1 - 0.042 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Telomere_Sde2 PF13019.1 EMD65947.1 - 0.046 13.4 0.3 0.072 12.7 0.2 1.5 1 1 0 1 1 1 0 Telomere stability and silencing NACHT PF05729.7 EMD65948.1 - 3.1e-05 23.7 0.0 8.7e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_12 PF13424.1 EMD65948.1 - 0.00051 19.9 2.4 0.005 16.7 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 EMD65948.1 - 0.0007 19.6 1.0 0.0088 16.0 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain TPR_11 PF13414.1 EMD65948.1 - 0.0013 18.3 0.0 0.0038 16.8 0.0 1.8 1 0 0 1 1 1 1 TPR repeat ZZ PF00569.12 EMD65948.1 - 0.73 9.4 5.4 1.5 8.4 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF3425 PF11905.3 EMD65950.1 - 4.4e-22 78.4 1.1 5.3e-22 78.1 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ADC PF06314.6 EMD65951.1 - 1.1e-39 136.1 0.0 1.3e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) adh_short PF00106.20 EMD65952.1 - 5.8e-13 49.0 0.1 9.7e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD65952.1 - 1.1e-05 25.1 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD65952.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EIIA-man PF03610.11 EMD65952.1 - 0.087 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 PTS system fructose IIA component Enoyl_reductase PF12241.3 EMD65952.1 - 0.2 10.6 1.0 2.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region Peptidase_C39_2 PF13529.1 EMD65953.1 - 0.034 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family KaiC PF06745.8 EMD65956.1 - 0.045 12.8 0.2 0.13 11.3 0.1 1.8 1 1 0 1 1 1 0 KaiC Exonuc_VII_L PF02601.10 EMD65957.1 - 0.036 13.2 0.8 0.052 12.7 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSCB_C PF07743.8 EMD65957.1 - 1.3 9.5 3.9 1.3 9.5 0.5 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain ATP-synt_B PF00430.13 EMD65957.1 - 7.5 6.3 9.3 14 5.4 3.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) MARVEL PF01284.18 EMD65958.1 - 0.11 12.3 13.5 0.26 11.1 9.2 1.7 1 1 1 2 2 2 0 Membrane-associating domain CbiQ PF02361.11 EMD65958.1 - 0.36 10.3 4.8 0.062 12.8 0.9 1.5 2 0 0 2 2 2 0 Cobalt transport protein DUF4137 PF13593.1 EMD65959.1 - 1.1e-92 310.5 28.8 1.2e-92 310.3 20.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) 5-FTHF_cyc-lig PF01812.15 EMD65960.1 - 0.00028 20.6 0.0 0.00066 19.4 0.0 1.5 1 1 1 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family FMN_red PF03358.10 EMD65961.1 - 8.5e-24 83.7 0.0 1.6e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EMD65961.1 - 0.058 12.9 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold PGA2 PF07543.7 EMD65963.1 - 0.19 11.4 0.1 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 His_Phos_1 PF00300.17 EMD65964.1 - 4.8e-18 65.7 0.0 1.1e-17 64.5 0.0 1.5 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) HET PF06985.6 EMD65965.1 - 5e-31 107.7 0.1 5e-31 107.7 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 EMD65965.1 - 0.078 12.8 11.2 0.086 12.7 0.1 5.1 5 1 0 5 5 5 0 WD domain, G-beta repeat Nop14 PF04147.7 EMD65965.1 - 0.08 10.8 12.2 0.12 10.2 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 EMD65965.1 - 0.096 12.2 11.3 0.17 11.4 7.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EMD65965.1 - 0.1 10.6 9.5 0.16 10.0 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 EMD65965.1 - 0.3 10.9 12.7 0.53 10.1 8.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TFIIF_alpha PF05793.7 EMD65965.1 - 1.5 7.1 20.5 2.4 6.4 14.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 EMD65965.1 - 1.5 8.0 15.7 2.8 7.1 10.9 1.3 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.13 EMD65965.1 - 6 5.1 12.6 8.9 4.5 8.7 1.1 1 0 0 1 1 1 0 Hsp90 protein RRN3 PF05327.6 EMD65965.1 - 7.2 4.5 8.3 11 3.9 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_61 PF03443.9 EMD65966.1 - 1e-63 215.0 0.1 1.3e-63 214.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.2 EMD65967.1 - 2.6e-36 123.8 0.0 2.4e-11 43.8 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD65967.1 - 5.7e-25 87.2 0.1 1.8e-07 31.4 0.0 5.9 4 2 3 7 7 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EMD65967.1 - 8.9e-24 82.0 0.0 0.0011 18.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EMD65967.1 - 9.3e-19 67.0 0.0 6.8e-05 22.9 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD65967.1 - 5.3e-15 54.0 0.0 0.011 15.9 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.7 EMD65967.1 - 4.8e-12 45.8 0.1 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EMD65967.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EMD65967.1 - 0.025 14.7 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EMD65967.1 - 0.03 14.4 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD65967.1 - 0.064 13.0 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 EMD65967.1 - 0.1 11.5 0.0 0.65 8.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.20 EMD65968.1 - 1.9e-09 37.0 0.0 4.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD65968.1 - 2.4e-05 23.5 0.0 5.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M28 PF04389.12 EMD65970.1 - 6.7e-39 133.4 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sugar_tr PF00083.19 EMD65972.1 - 7.8e-81 271.9 12.6 8.8e-81 271.7 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD65972.1 - 2.9e-10 39.3 32.2 1.6e-05 23.8 16.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EMD65973.1 - 1.5e-20 73.7 2.5 1.9e-20 73.4 1.7 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAP59_mtransfer PF11735.3 EMD65973.1 - 0.077 12.2 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF385 PF04075.9 EMD65973.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF385) Methyltransf_2 PF00891.13 EMD65975.1 - 1e-31 109.9 0.0 2.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMD65975.1 - 0.00088 19.8 0.1 0.0042 17.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD65975.1 - 0.049 14.1 0.0 0.24 11.8 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMD65975.1 - 0.075 13.4 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain NGP1NT PF08153.7 EMD65976.1 - 1.5e-43 147.8 0.0 2.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EMD65976.1 - 8.2e-19 67.6 0.0 9.8e-14 51.3 0.0 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD65976.1 - 2.2e-05 23.7 0.0 0.00055 19.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMD65976.1 - 0.0015 18.3 4.3 0.55 10.0 0.0 3.9 4 1 1 5 5 5 1 Dynamin family Arf PF00025.16 EMD65976.1 - 0.0038 16.4 0.0 0.084 12.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EMD65976.1 - 0.0066 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMD65976.1 - 0.011 15.1 0.0 0.44 9.9 0.0 3.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Sigma70_ner PF04546.8 EMD65976.1 - 1.2 8.6 16.6 2.4 7.7 11.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.27 EMD65978.1 - 1.2e-44 148.6 8.5 2.8e-13 49.1 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 EMD65978.1 - 1.2e-14 54.2 1.4 2.1e-12 47.0 1.0 2.3 1 1 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD65978.1 - 6.4e-08 31.1 2.6 0.049 11.7 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMD65978.1 - 1.3e-05 24.7 1.2 0.00031 20.2 0.1 2.0 1 1 1 2 2 2 1 PQQ-like domain PDDEXK_1 PF12705.2 EMD65978.1 - 0.0027 17.1 0.0 0.78 9.0 0.0 3.2 1 1 2 3 3 3 1 PD-(D/E)XK nuclease superfamily PQQ_3 PF13570.1 EMD65978.1 - 0.016 15.4 1.9 10 6.5 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain AAA_19 PF13245.1 EMD65978.1 - 0.035 13.8 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EMD65978.1 - 0.035 14.2 0.3 0.27 11.4 0.1 2.4 3 0 0 3 3 3 0 RNA helicase Cytochrom_D1 PF02239.11 EMD65978.1 - 0.038 12.3 0.5 0.29 9.3 0.0 2.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain NTPase_1 PF03266.10 EMD65978.1 - 0.32 10.6 0.6 9.8 5.8 0.1 2.4 2 0 0 2 2 2 0 NTPase HTH_Tnp_Tc5 PF03221.11 EMD65979.1 - 2.1e-11 43.4 0.0 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD65979.1 - 6e-06 25.7 0.2 1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD65979.1 - 0.0044 17.1 1.3 0.0074 16.4 0.4 1.7 1 1 1 2 2 2 1 Winged helix-turn helix DUF2500 PF10694.4 EMD65979.1 - 0.035 14.1 0.6 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Drf_GBD PF06371.8 EMD65979.1 - 0.04 13.2 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_28 PF13518.1 EMD65979.1 - 0.068 13.1 0.1 0.39 10.7 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD65979.1 - 0.084 12.5 0.2 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain MFS_1 PF07690.11 EMD65980.1 - 2.7e-16 59.2 59.0 3.6e-15 55.5 18.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD65980.1 - 5.6e-12 44.6 13.0 5.6e-12 44.6 9.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transferase PF02458.10 EMD65981.1 - 4e-06 25.5 0.0 8e-06 24.5 0.0 1.4 1 1 0 1 1 1 1 Transferase family CDC27 PF09507.5 EMD65982.1 - 0.29 10.3 16.4 0.4 9.8 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.7 EMD65982.1 - 1.6 7.8 16.5 2.4 7.3 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 EMD65982.1 - 1.8 8.5 19.1 2.7 8.0 13.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 EMD65982.1 - 3.8 6.8 23.1 4.3 6.6 15.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DNA_pol_phi PF04931.8 EMD65982.1 - 7.6 4.1 28.1 10 3.7 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mitofilin PF09731.4 EMD65983.1 - 0.024 13.3 2.8 0.028 13.0 1.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Radial_spoke_3 PF06098.6 EMD65983.1 - 0.12 11.4 3.2 0.12 11.3 2.2 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 DP PF08781.5 EMD65983.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Transcription factor DP DUF2570 PF10828.3 EMD65983.1 - 0.14 11.7 1.0 0.18 11.4 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1053 PF06327.9 EMD65983.1 - 0.2 12.0 0.7 0.22 11.8 0.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) SnoaL_4 PF13577.1 EMD65985.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 EMD65987.1 - 7.9e-18 64.2 40.9 9.1e-18 64.0 22.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD65987.1 - 0.0093 14.5 35.7 0.11 11.0 24.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF764 PF05561.6 EMD65987.1 - 0.1 11.9 0.8 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF764) DUF3098 PF11297.3 EMD65987.1 - 0.14 11.9 5.8 0.12 12.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Rubis-subs-bind PF09273.6 EMD65988.1 - 2e-11 43.8 1.5 2e-11 43.8 1.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EMD65988.1 - 5.7e-11 42.9 0.0 9.5e-10 39.0 0.0 2.6 2 1 0 2 2 2 1 SET domain Nucleoplasmin PF03066.10 EMD65988.1 - 1.4 8.4 6.8 1.4 8.4 1.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EMD65988.1 - 1.9 8.8 10.8 1.8 8.8 2.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.1 EMD65989.1 - 9.3e-06 25.3 0.2 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD65989.1 - 0.0028 17.7 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMD65989.1 - 0.0079 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMD65989.1 - 0.02 14.9 0.7 0.044 13.7 0.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD65989.1 - 0.035 13.8 0.2 0.06 13.0 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Dynamin_N PF00350.18 EMD65991.1 - 1.4e-14 54.2 0.1 8.9e-14 51.6 0.0 2.4 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EMD65991.1 - 2.6e-06 27.3 0.0 0.0013 18.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMD65991.1 - 0.0001 21.5 0.0 0.0025 17.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EMD65991.1 - 0.019 15.4 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EMD65991.1 - 0.025 14.5 0.4 0.12 12.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EMD65991.1 - 0.074 13.3 1.1 0.25 11.6 0.0 2.5 3 0 0 3 3 3 0 ABC transporter DUF342 PF03961.8 EMD65991.1 - 0.2 10.0 10.9 0.057 11.8 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Iso_dh PF00180.15 EMD65992.1 - 1.7e-94 316.6 0.0 2.5e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 EMD65992.1 - 0.033 13.9 0.1 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) DUF1769 PF08588.5 EMD65993.1 - 1e-26 92.6 0.4 1.9e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3506 PF12014.3 EMD65994.1 - 2e-41 140.9 0.0 2.5e-27 95.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3506) F-box-like PF12937.2 EMD65994.1 - 1.4e-08 34.2 0.6 3.7e-08 32.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD65994.1 - 3.8e-07 29.6 1.5 6.7e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 EMD65994.1 - 0.012 16.0 0.1 0.012 16.0 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RNase_H PF00075.19 EMD65999.1 - 7.4e-14 52.2 0.1 9.1e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMD65999.1 - 2.4e-07 30.4 0.2 5.1e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like KAR9 PF08580.5 EMD66000.1 - 4.3 5.4 7.3 6.7 4.8 5.0 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Asp PF00026.18 EMD66001.1 - 4.7e-12 45.7 0.0 6.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.6 EMD66001.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Podoplanin Herpes_gE PF02480.11 EMD66001.1 - 0.072 11.3 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EMD66001.1 - 0.23 10.0 0.2 0.34 9.5 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EMD66001.1 - 1.3 8.4 6.1 2.2 7.6 4.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Methyltransf_2 PF00891.13 EMD66002.1 - 1.5e-25 89.8 0.3 5.2e-25 88.0 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMD66002.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.1 EMD66003.1 - 1.9e-19 69.9 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD66003.1 - 3.1e-11 43.0 0.0 9.4e-10 38.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD66003.1 - 4.3e-09 36.7 0.0 2.3e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD66003.1 - 1.4e-08 35.1 0.0 3.9e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66003.1 - 1.4e-08 35.2 0.1 2e-07 31.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMD66003.1 - 0.00019 20.5 0.0 0.00051 19.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EMD66003.1 - 0.00021 20.7 0.0 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMD66003.1 - 0.0007 19.6 0.1 0.013 15.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD66003.1 - 0.00082 19.7 0.0 0.0026 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMD66003.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EMD66003.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EMD66003.1 - 0.04 13.8 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Sod_Fe_N PF00081.17 EMD66004.1 - 3.7e-35 120.0 4.1 8.3e-35 118.9 0.9 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EMD66004.1 - 3.9e-35 119.8 0.7 6.3e-35 119.2 0.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain SR-25 PF10500.4 EMD66005.1 - 9.6 5.6 16.6 1.6 8.1 7.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Na_H_Exchanger PF00999.16 EMD66006.1 - 1.2e-30 106.3 37.8 5.8e-25 87.6 17.4 2.6 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Pex14_N PF04695.8 EMD66006.1 - 0.033 14.2 0.2 1.6 8.7 0.0 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_cc PF11790.3 EMD66007.1 - 7.5e-31 107.3 2.0 1.4e-19 70.5 1.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase catalytic core Asparaginase PF00710.15 EMD66008.1 - 5.3e-46 156.9 0.0 6.9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase HET PF06985.6 EMD66009.1 - 1e-22 80.7 0.0 1.9e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 EMD66011.1 - 2.2e-143 477.6 0.0 1.7e-79 267.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EMD66011.1 - 5.5e-119 396.4 0.0 2.7e-40 138.1 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EMD66011.1 - 3.5e-21 75.2 0.3 7e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD66011.1 - 2.4e-12 47.6 0.0 7.8e-05 23.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain RNase_H PF00075.19 EMD66012.1 - 2.2e-11 44.2 0.0 3.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF3018 PF11455.3 EMD66012.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) DDE_1 PF03184.14 EMD66013.1 - 2.8e-31 108.3 0.0 3.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMD66013.1 - 4e-07 29.8 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMD66013.1 - 0.0073 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD66014.1 - 9.8e-05 21.8 0.9 9.8e-05 21.8 0.6 1.9 1 1 1 2 2 2 1 helix-turn-helix, Psq domain DUF3413 PF11893.3 EMD66014.1 - 0.0002 20.3 0.2 0.00021 20.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) CENP-B_N PF04218.8 EMD66014.1 - 0.0027 17.1 0.4 0.24 10.8 0.0 2.1 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 EMD66014.1 - 0.075 13.0 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain BrkDBD PF09607.5 EMD66014.1 - 0.089 12.3 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 Brinker DNA-binding domain ABC_membrane PF00664.18 EMD66015.1 - 2e-75 253.7 37.7 2.3e-40 138.7 10.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD66015.1 - 5.1e-65 217.8 0.0 2.2e-34 118.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD66015.1 - 1.2e-14 54.1 5.1 5.1e-08 32.4 0.1 4.2 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD66015.1 - 1.3e-13 51.6 0.8 0.00014 21.8 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMD66015.1 - 2.8e-08 33.1 0.4 0.00033 20.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD66015.1 - 7.6e-08 32.5 0.5 0.031 14.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EMD66015.1 - 1.5e-07 30.3 0.0 0.035 12.7 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMD66015.1 - 2.7e-07 30.7 2.8 0.0047 16.9 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EMD66015.1 - 5.3e-07 28.9 0.0 0.035 13.2 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EMD66015.1 - 6.1e-07 29.2 0.2 0.045 13.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMD66015.1 - 1.1e-06 29.4 0.0 0.033 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD66015.1 - 2e-06 27.3 0.0 0.06 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMD66015.1 - 0.00014 21.4 0.1 0.28 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 EMD66015.1 - 0.00018 21.8 0.1 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMD66015.1 - 0.00021 21.5 2.2 14 5.9 0.2 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMD66015.1 - 0.00042 20.2 0.0 2.6 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EMD66015.1 - 0.00057 19.5 0.0 0.06 13.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EMD66015.1 - 0.00099 19.4 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EMD66015.1 - 0.0012 18.5 0.2 0.37 10.4 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMD66015.1 - 0.0014 18.4 0.0 0.54 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMD66015.1 - 0.0016 17.9 0.0 0.84 9.0 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EMD66015.1 - 0.0029 17.5 0.7 0.23 11.4 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EMD66015.1 - 0.0039 17.0 0.9 3.4 7.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EMD66015.1 - 0.005 16.8 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMD66015.1 - 0.0079 15.9 0.0 4.1 7.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EMD66015.1 - 0.013 14.5 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EMD66015.1 - 0.018 14.1 0.8 1.5 7.9 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin RNA_helicase PF00910.17 EMD66015.1 - 0.02 15.0 0.0 16 5.7 0.0 3.3 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.12 EMD66015.1 - 0.02 14.4 0.1 0.37 10.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 EMD66015.1 - 0.031 12.9 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 EMD66015.1 - 0.046 13.2 0.0 9.3 5.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EMD66015.1 - 0.064 13.2 0.0 17 5.3 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EMD66015.1 - 0.12 11.1 0.1 6.1 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain 3HCDH_N PF02737.13 EMD66016.1 - 4.3e-31 107.9 0.0 6.4e-30 104.1 0.0 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMD66016.1 - 5.6e-13 49.1 0.1 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EMD66016.1 - 0.052 13.2 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EMD66016.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMD66016.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EMD66017.1 - 5.1e-69 232.6 0.0 6.7e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EMD66017.1 - 3.2e-06 27.3 0.0 6.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD66017.1 - 0.00045 21.1 0.0 0.0013 19.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EMD66018.1 - 5.1e-25 88.3 2.8 2.1e-24 86.2 1.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMD66018.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMD66018.1 - 2.3e-09 37.4 0.2 4.4e-09 36.4 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD66018.1 - 2.7e-09 36.9 0.5 3.8e-09 36.4 0.4 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD66018.1 - 3e-06 27.3 0.1 1.1e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD66018.1 - 0.0017 17.2 0.1 0.0024 16.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMD66018.1 - 0.0027 16.6 0.1 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EMD66018.1 - 0.05 12.8 0.1 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 EMD66018.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain zf-RVT PF13966.1 EMD66019.1 - 0.032 14.5 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase NEL PF14496.1 EMD66019.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting RVT_1 PF00078.22 EMD66020.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MRFAP1 PF15155.1 EMD66021.1 - 0.043 14.1 3.9 0.042 14.1 1.6 1.8 2 0 0 2 2 2 0 MORF4 family-associated protein1 RVT_1 PF00078.22 EMD66023.1 - 0.018 14.3 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EMD66024.1 - 4.2e-06 26.3 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMD66024.1 - 0.024 14.5 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1132 PF06575.7 EMD66024.1 - 0.11 12.7 0.1 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) eIF3g PF12353.3 EMD66025.1 - 0.14 12.0 14.1 0.1 12.5 0.5 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G COG2 PF06148.6 EMD66025.1 - 0.67 9.8 2.5 1.4 8.7 1.4 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pol_alpha_B_N PF08418.5 EMD66025.1 - 3.8 6.9 11.7 0.78 9.2 2.2 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal HTH_psq PF05225.11 EMD66026.1 - 1.8e-08 33.8 0.2 2.2e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_10 PF04967.7 EMD66026.1 - 0.0053 16.3 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 HTH DNA binding domain CENP-B_N PF04218.8 EMD66026.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 EMD66026.1 - 0.12 12.4 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE_1 PF03184.14 EMD66028.1 - 1.2e-51 174.9 0.0 3.6e-51 173.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMD66028.1 - 3.7e-09 36.2 2.1 2.2e-07 30.5 0.0 3.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD66028.1 - 8.2e-07 28.4 0.2 2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Cytochrom_C550 PF14495.1 EMD66028.1 - 0.08 12.3 2.0 0.14 11.5 0.8 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain zf-CCHC_4 PF14392.1 EMD66028.1 - 0.11 12.1 0.7 0.22 11.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle G-gamma PF00631.17 EMD66028.1 - 2.5 7.8 9.0 4.9 6.9 0.6 2.8 2 0 0 2 2 2 0 GGL domain DUF3573 PF12097.3 EMD66028.1 - 4.2 5.8 4.8 6.2 5.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Exo_endo_phos_2 PF14529.1 EMD66029.1 - 3.6e-07 29.8 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EMD66029.1 - 0.0021 18.0 0.0 0.0023 17.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.13 EMD66030.1 - 2.9e-05 23.0 0.3 6.3e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3189 PF11385.3 EMD66031.1 - 0.051 13.1 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) F-box-like PF12937.2 EMD66032.1 - 1.3e-05 24.8 1.8 1.3e-05 24.7 0.4 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD66032.1 - 9.8e-05 21.9 1.4 9.8e-05 21.9 1.0 1.9 2 0 0 2 2 2 1 F-box domain MCPVI PF02993.9 EMD66033.1 - 0.096 12.8 6.8 0.12 12.4 4.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Pkinase PF00069.20 EMD66034.1 - 6.3e-33 114.0 0.0 2.2e-32 112.2 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66034.1 - 2.1e-18 66.3 0.0 1.9e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD66034.1 - 0.00031 20.5 0.0 0.00075 19.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD66034.1 - 0.0034 16.4 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD66034.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pec_lyase_N PF04431.8 EMD66035.1 - 0.0041 17.1 1.7 0.0067 16.4 0.1 2.0 2 0 0 2 2 2 1 Pectate lyase, N terminus T2SJ PF11612.3 EMD66035.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J Rapamycin_bind PF08771.6 EMD66035.1 - 0.034 14.2 0.4 0.078 13.0 0.2 1.7 2 0 0 2 2 2 0 Rapamycin binding domain Laminin_I PF06008.9 EMD66035.1 - 0.11 11.8 2.7 0.15 11.3 1.9 1.1 1 0 0 1 1 1 0 Laminin Domain I BTB PF00651.26 EMD66036.1 - 1.9e-08 34.3 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Dynamin_N PF00350.18 EMD66037.1 - 3.4e-29 101.8 0.0 7.2e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMD66037.1 - 1.5e-19 69.9 0.0 4.9e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EMD66037.1 - 0.00033 20.5 0.0 0.0071 16.2 0.0 3.2 3 2 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EMD66037.1 - 0.0094 16.4 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein GED PF02212.13 EMD66037.1 - 0.011 15.5 0.8 0.28 11.1 0.0 3.2 3 0 0 3 3 3 0 Dynamin GTPase effector domain AAA_21 PF13304.1 EMD66037.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMD66037.1 - 0.052 12.8 0.0 4.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AHH PF14412.1 EMD66037.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH AAA_29 PF13555.1 EMD66037.1 - 0.11 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BTB PF00651.26 EMD66038.1 - 6.1e-12 45.5 0.0 9.8e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EMD66041.1 - 1.4e-10 41.1 0.1 2.3e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-RING_2 PF13639.1 EMD66042.1 - 2.7e-12 46.2 4.5 5e-12 45.4 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD66042.1 - 6.6e-08 32.5 5.1 4.1e-07 30.0 3.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD66042.1 - 2.1e-06 27.2 5.6 3.8e-06 26.4 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD66042.1 - 1.8e-05 24.3 3.4 3.5e-05 23.3 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD66042.1 - 4.8e-05 23.3 5.8 9.7e-05 22.3 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD66042.1 - 0.00095 18.9 3.8 0.051 13.4 2.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TMEM247 PF15444.1 EMD66042.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 247 zf-RING_5 PF14634.1 EMD66042.1 - 0.003 17.2 4.9 0.0059 16.3 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EMD66042.1 - 0.07 12.7 3.7 0.15 11.6 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EMD66042.1 - 0.08 12.9 8.8 2.7 8.0 6.1 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain PRTase_1 PF11202.3 EMD66042.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) UPF0547 PF10571.4 EMD66042.1 - 0.12 12.0 0.5 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RINGv PF12906.2 EMD66042.1 - 0.28 11.2 3.3 0.73 9.9 2.3 1.7 1 1 0 1 1 1 0 RING-variant domain Methyltransf_23 PF13489.1 EMD66043.1 - 6.1e-23 81.3 0.0 9.1e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD66043.1 - 1.5e-18 66.8 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD66043.1 - 1.6e-17 63.5 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EMD66043.1 - 2.8e-17 62.9 0.0 4.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66043.1 - 7e-16 58.7 0.0 1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD66043.1 - 1.2e-14 54.6 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD66043.1 - 8.3e-14 51.6 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD66043.1 - 2e-09 36.9 0.0 5.2e-08 32.2 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMD66043.1 - 8.5e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMD66043.1 - 1.1e-07 32.1 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMD66043.1 - 3.8e-07 29.1 0.0 5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 EMD66043.1 - 9e-07 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EMD66043.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EMD66043.1 - 2.5e-06 26.8 0.0 3.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EMD66043.1 - 4.4e-06 26.4 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EMD66043.1 - 8.8e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.9 EMD66043.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EMD66043.1 - 0.0002 21.0 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMD66043.1 - 0.00028 19.9 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 EMD66043.1 - 0.00035 19.9 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EMD66043.1 - 0.0019 18.9 0.1 0.0034 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EMD66043.1 - 0.0022 17.4 0.0 0.0033 16.9 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.13 EMD66043.1 - 0.0043 16.5 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 DNA methylase RrnaAD PF00398.15 EMD66043.1 - 0.0052 15.8 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 EMD66043.1 - 0.032 13.5 0.2 0.41 9.9 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain UPF0146 PF03686.8 EMD66043.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.13 EMD66043.1 - 0.042 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cons_hypoth95 PF03602.10 EMD66043.1 - 0.044 13.1 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.4 EMD66043.1 - 0.079 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Herpes_UL69 PF05459.7 EMD66044.1 - 0.0012 18.0 0.1 0.0023 17.1 0.0 1.4 1 1 0 2 2 2 1 Herpesvirus transcriptional regulator family SET PF00856.23 EMD66047.1 - 4.2e-12 46.6 0.0 7.5e-11 42.6 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EMD66047.1 - 7.9e-10 38.2 0.9 1.2e-08 34.5 0.3 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EMD66047.1 - 1.8e-06 27.3 2.6 0.2 11.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD66047.1 - 0.00043 19.7 3.2 0.0047 16.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD66047.1 - 0.0012 19.4 0.3 4.7 7.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD66047.1 - 0.0018 18.6 0.1 3.2 8.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD66047.1 - 0.0029 17.4 0.8 0.051 13.4 0.0 2.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EMD66047.1 - 0.0033 17.5 1.0 0.018 15.1 0.7 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMD66047.1 - 0.0058 17.1 0.3 0.034 14.7 0.0 2.5 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66047.1 - 0.03 14.2 2.6 5.6 6.9 0.3 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD66047.1 - 0.037 14.4 0.2 0.54 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CMV_1a PF12467.3 EMD66051.1 - 0.015 15.6 5.5 0.021 15.2 3.8 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family GCR PF02155.10 EMD66051.1 - 0.18 10.4 5.8 0.069 11.8 2.1 1.6 2 1 0 2 2 2 0 Glucocorticoid receptor Peptidase_S49_N PF08496.5 EMD66051.1 - 1.9 8.2 9.1 0.41 10.4 3.4 2.0 2 1 1 3 3 3 0 Peptidase family S49 N-terminal Chitin_bind_3 PF03067.10 EMD66052.1 - 0.0094 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain CBM_19 PF03427.8 EMD66052.1 - 0.035 13.8 7.2 0.13 12.0 5.0 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Glyco_hydro_61 PF03443.9 EMD66052.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DDE_1 PF03184.14 EMD66053.1 - 9.8e-23 80.4 0.0 1.7e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease COesterase PF00135.23 EMD66054.1 - 2e-104 350.2 0.0 2.6e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD66054.1 - 9.4e-07 28.6 0.1 1.8e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD66054.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Synaptobrevin PF00957.16 EMD66055.1 - 4.5e-31 106.3 0.0 6.5e-31 105.7 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMD66055.1 - 2.3e-13 49.4 0.0 5.2e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF1443 PF07280.6 EMD66055.1 - 4.8 6.8 7.5 8.2 6.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) RNase_P_Rpp14 PF01900.14 EMD66056.1 - 4.5e-31 106.9 0.0 2.6e-30 104.4 0.0 1.9 1 1 0 1 1 1 1 Rpp14/Pop5 family MFS_1 PF07690.11 EMD66057.1 - 0.00014 20.6 6.9 0.0002 20.2 4.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 EMD66059.1 - 1e-07 31.7 14.9 4.1e-07 29.7 10.3 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBN2 PF14223.1 EMD66063.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_6 PF13912.1 EMD66064.1 - 1.5e-05 24.6 16.0 0.017 14.9 0.3 4.8 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMD66064.1 - 2e-05 24.5 28.1 0.077 13.3 0.8 5.8 5 1 1 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD66064.1 - 0.1 12.7 17.7 0.68 10.1 0.2 5.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMD66064.1 - 0.27 11.6 0.2 0.18 12.1 2.7 5.9 7 0 0 7 7 7 0 Zinc finger, C2H2 type APH PF01636.18 EMD66065.1 - 2.3e-12 47.1 0.0 3.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMD66065.1 - 0.00055 19.1 0.0 0.015 14.5 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Choline_kinase PF01633.15 EMD66065.1 - 0.002 17.7 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EMD66065.1 - 0.063 12.0 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 EMD66065.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF972 PF06156.8 EMD66066.1 - 0.063 13.6 0.1 0.17 12.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pup PF05639.6 EMD66066.1 - 0.092 13.2 0.7 0.25 11.8 0.5 1.8 1 0 0 1 1 1 0 Pup-like protein YhzD PF14120.1 EMD66066.1 - 0.55 10.1 0.1 0.55 10.1 0.1 2.4 3 0 0 3 3 3 0 YhzD-like protein bZIP_1 PF00170.16 EMD66067.1 - 4e-07 29.8 12.5 4.6e-07 29.6 8.6 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD66067.1 - 0.0012 18.6 14.6 0.0014 18.3 10.1 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD66067.1 - 0.01 16.1 8.9 0.011 15.9 6.1 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF484 PF04340.7 EMD66067.1 - 0.037 13.4 4.5 0.045 13.2 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF87 PF01935.12 EMD66067.1 - 0.09 12.5 1.0 0.1 12.4 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 HALZ PF02183.13 EMD66067.1 - 0.11 12.2 2.4 0.18 11.5 1.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.13 EMD66067.1 - 0.12 12.3 0.7 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family SpaB_C PF14028.1 EMD66067.1 - 0.3 10.6 3.3 0.32 10.4 2.3 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain EAP30 PF04157.11 EMD66067.1 - 0.4 9.8 5.0 0.45 9.6 3.5 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DivIC PF04977.10 EMD66067.1 - 1.1 8.7 8.1 0.56 9.7 3.7 1.8 1 1 1 2 2 2 0 Septum formation initiator Wbp11 PF09429.5 EMD66067.1 - 5 7.1 13.2 8 6.5 9.0 1.5 1 1 0 1 1 1 0 WW domain binding protein 11 GTP1_OBG PF01018.17 EMD66068.1 - 0.067 12.8 0.0 0.068 12.8 0.0 1.0 1 0 0 1 1 1 0 GTP1/OBG zf-MYND PF01753.13 EMD66069.1 - 1.9e-09 37.2 16.1 3.9e-09 36.2 11.2 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EMD66069.1 - 3.4 7.0 7.2 8.5 5.7 5.0 1.7 1 1 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 EMD66069.1 - 3.5 7.5 8.8 7.5 6.4 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_10 PF13374.1 EMD66071.1 - 1.7e-21 75.4 0.4 2.6e-11 43.0 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66071.1 - 5.4e-18 64.7 1.5 1.6e-12 47.1 0.1 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD66071.1 - 7e-05 22.3 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EMD66071.1 - 0.00044 19.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD66071.1 - 0.00069 19.2 0.2 0.081 12.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMD66071.1 - 0.0033 17.7 0.1 0.0094 16.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EMD66071.1 - 0.0045 17.0 0.2 0.17 12.0 0.0 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD66071.1 - 0.0054 17.0 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD66071.1 - 0.065 13.3 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMD66071.1 - 0.089 12.4 0.0 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.1 EMD66071.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.15 EMD66071.1 - 0.24 11.4 0.9 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 PPR repeat DUF3189 PF11385.3 EMD66073.1 - 0.088 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) p450 PF00067.17 EMD66075.1 - 6.5e-74 249.1 0.0 7.6e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wax2_C PF12076.3 EMD66075.1 - 0.047 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain DUF2360 PF10152.4 EMD66081.1 - 1.5 9.1 4.8 1.4 9.1 3.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-3CxxC PF13695.1 EMD66086.1 - 2.2e-22 79.0 5.8 2.2e-22 79.0 4.0 2.4 2 0 0 2 2 2 1 Zinc-binding domain zf-C2H2_jaz PF12171.3 EMD66086.1 - 4.9e-05 23.3 0.6 4.9e-05 23.3 0.4 3.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD66086.1 - 0.001 19.2 8.8 0.0058 16.7 0.4 4.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD66086.1 - 0.0033 17.2 0.4 0.0033 17.2 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2992 PF11208.3 EMD66089.1 - 0.44 10.4 5.3 0.51 10.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2949 PF11165.3 EMD66089.1 - 1 9.6 3.5 14 5.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2949) DUF3658 PF12395.3 EMD66091.1 - 0.086 12.4 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function 2-Hacid_dh_C PF02826.14 EMD66095.1 - 2.4e-35 121.2 0.0 4.4e-35 120.4 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD66095.1 - 5e-21 74.5 0.0 6.1e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 EMD66095.1 - 0.00054 19.5 0.1 0.26 10.8 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EMD66095.1 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 EMD66095.1 - 0.035 14.4 0.0 6.2 7.1 0.0 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EMD66095.1 - 0.057 13.2 0.1 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TSNR_N PF04705.7 EMD66095.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Spt20 PF12090.3 EMD66096.1 - 5.8e-39 133.3 0.0 5.8e-39 133.3 0.0 5.6 3 1 0 3 3 3 1 Spt20 family Polyketide_cyc2 PF10604.4 EMD66097.1 - 8.2e-07 29.2 0.2 9.5e-07 29.0 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Bet_v_1 PF00407.14 EMD66097.1 - 0.00074 19.1 0.5 0.00087 18.9 0.4 1.1 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family HSP20 PF00011.16 EMD66098.1 - 1.6e-12 47.2 0.1 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GMC_oxred_N PF00732.14 EMD66099.1 - 5.7e-46 157.0 0.0 7.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD66099.1 - 2.6e-31 108.8 0.0 5.9e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMD66099.1 - 0.0014 17.6 0.3 0.0047 15.8 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMD66099.1 - 0.022 13.6 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD66099.1 - 0.054 13.5 0.1 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMD66099.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AstE_AspA PF04952.9 EMD66101.1 - 2e-32 112.2 0.0 2.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M23 PF01551.17 EMD66101.1 - 0.02 14.9 0.0 0.09 12.8 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M23 DUF77 PF01910.12 EMD66101.1 - 0.082 12.5 0.1 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF77 Ank_2 PF12796.2 EMD66102.1 - 4.5e-21 75.0 4.9 1.9e-08 34.4 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMD66102.1 - 1e-10 40.8 6.4 0.0052 16.5 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMD66102.1 - 4.6e-09 36.5 0.0 0.01 16.3 0.0 4.2 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD66102.1 - 1.7e-07 30.8 0.3 0.11 12.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMD66102.1 - 0.0096 16.1 0.2 12 6.2 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeats (many copies) TPR_7 PF13176.1 EMD66102.1 - 0.07 12.9 0.4 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.6 EMD66103.1 - 2.1e-38 131.6 4.8 3.2e-38 131.0 3.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1835 PF08874.5 EMD66103.1 - 0.031 14.2 0.5 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) OMPdecase PF00215.19 EMD66105.1 - 3.5e-77 258.8 0.0 4.2e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family AT_hook PF02178.14 EMD66106.1 - 0.057 13.1 3.9 0.057 13.1 2.7 3.3 3 0 0 3 3 3 0 AT hook motif JSRP PF15312.1 EMD66106.1 - 1.9 8.5 4.4 6.9 6.7 3.0 2.0 1 1 0 1 1 1 0 Junctional sarcoplasmic reticulum protein SDA1 PF05285.7 EMD66107.1 - 5.8e-85 285.4 30.4 5.8e-85 285.4 21.1 2.7 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 EMD66107.1 - 5.3e-17 61.8 0.1 1.5e-16 60.4 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain CPSF_A PF03178.10 EMD66108.1 - 2.3e-84 283.2 0.0 1e-83 281.1 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EMD66108.1 - 2.3e-51 174.5 0.0 4.1e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term EthD PF07110.6 EMD66109.1 - 1.4e-08 35.4 1.1 2.4e-08 34.7 0.7 1.4 1 1 0 1 1 1 1 EthD domain bZIP_1 PF00170.16 EMD66112.1 - 9.6e-08 31.8 15.1 1.1e-07 31.7 8.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMD66112.1 - 0.0027 17.4 10.3 0.0027 17.4 7.2 3.1 3 1 0 3 3 3 1 Basic region leucine zipper BAF1_ABF1 PF04684.8 EMD66112.1 - 0.72 8.6 20.0 1.5 7.6 13.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 EMD66112.1 - 7.3 6.3 18.9 3.6 7.3 11.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4557) PPR_2 PF13041.1 EMD66113.1 - 6.6e-36 122.0 1.0 5.3e-09 35.9 0.0 8.8 7 1 2 9 9 9 7 PPR repeat family PPR_3 PF13812.1 EMD66113.1 - 2.1e-23 80.5 9.2 0.00018 21.4 0.0 9.5 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 EMD66113.1 - 7.5e-23 78.8 7.1 0.00012 21.8 0.0 7.9 8 0 0 8 8 8 5 PPR repeat PPR_1 PF12854.2 EMD66113.1 - 2e-11 43.1 0.2 0.0005 19.4 0.0 5.8 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EMD66113.1 - 0.016 15.7 4.5 4.8 8.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2007 PF09413.5 EMD66113.1 - 0.048 13.4 0.1 0.76 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2007) ECSIT PF06239.6 EMD66113.1 - 0.055 12.3 0.0 6.1 5.6 0.0 3.3 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.1 EMD66113.1 - 0.11 13.1 0.6 16 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat His_Phos_2 PF00328.17 EMD66114.1 - 4.9e-20 72.1 0.0 1.2e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PhoD PF09423.5 EMD66115.1 - 2.4e-159 530.7 6.8 2.8e-159 530.5 4.7 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_12 PF01670.11 EMD66116.1 - 9.7e-33 113.1 0.2 1.7e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EMD66116.1 - 0.032 14.3 5.6 0.11 12.7 0.3 2.8 2 1 1 3 3 3 0 Phage holin DUF936 PF06075.7 EMD66118.1 - 0.1 11.4 0.4 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CHRD PF07452.7 EMD66119.1 - 2.1e-05 25.1 0.0 6.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 CHRD domain DrsE_2 PF13686.1 EMD66122.1 - 0.066 12.9 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Rrn6 PF10214.4 EMD66122.1 - 0.16 9.9 2.1 0.21 9.6 1.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TAF4 PF05236.9 EMD66123.1 - 1.9e-17 63.4 1.7 2.4e-12 46.6 0.7 3.5 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 EMD66124.1 - 7.4e-67 224.8 0.0 6e-64 215.3 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EMD66124.1 - 1.2e-33 115.7 0.0 2.1e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EMD66124.1 - 1.3e-15 57.6 0.8 2.7e-15 56.5 0.5 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD66124.1 - 1.6e-10 40.8 1.0 6.7e-10 38.8 0.3 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EMD66124.1 - 4.9e-08 32.6 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EMD66124.1 - 2.1e-05 24.2 0.1 6.5e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_carr PF00153.22 EMD66125.1 - 3.7e-46 154.7 11.1 3.6e-17 61.8 0.5 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HSP70 PF00012.15 EMD66127.1 - 1.1e-11 43.4 0.3 7.9e-10 37.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EMD66127.1 - 0.0028 17.2 0.1 0.0065 16.0 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EMD66127.1 - 0.028 13.0 0.1 0.17 10.4 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.11 EMD66128.1 - 5.3e-23 81.2 16.6 5.3e-23 81.2 11.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Glt_symporter PF03616.9 EMD66128.1 - 0.087 11.3 0.1 0.17 10.3 0.1 1.5 1 0 0 1 1 1 0 Sodium/glutamate symporter MIF PF01187.13 EMD66130.1 - 2.7e-13 49.9 0.0 4.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) CENP-X PF09415.5 EMD66131.1 - 1.5e-22 79.2 0.0 2.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Copper-bind PF00127.15 EMD66132.1 - 0.0024 18.0 0.2 0.0038 17.4 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EMD66132.1 - 0.017 14.9 1.0 0.19 11.5 0.7 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain FRQ PF09421.5 EMD66132.1 - 1.6 6.3 4.8 1.7 6.2 3.4 1.1 1 0 0 1 1 1 0 Frequency clock protein HET PF06985.6 EMD66134.1 - 0.0006 19.9 0.5 0.00088 19.4 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EMD66135.1 - 8e-08 32.3 0.1 5.1e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMD66135.1 - 0.0064 15.1 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EMD66135.1 - 0.05 13.1 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LigB PF02900.13 EMD66137.1 - 4.5e-43 147.1 0.1 5.2e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Cu-oxidase_3 PF07732.10 EMD66138.1 - 4.4e-44 148.9 8.9 2.5e-42 143.3 1.2 3.9 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD66138.1 - 1.1e-41 141.6 7.7 1.3e-38 131.6 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMD66138.1 - 9.1e-37 126.4 2.1 1.9e-34 118.8 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EMD66138.1 - 0.0061 16.4 0.0 11 5.9 0.0 3.8 4 1 0 4 4 4 1 Cupredoxin-like domain FTR1 PF03239.9 EMD66139.1 - 9.4e-86 287.5 8.7 1.1e-85 287.2 6.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 EMD66139.1 - 0.0059 16.4 1.0 0.013 15.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF4282 PF14110.1 EMD66139.1 - 0.006 16.7 4.4 0.006 16.7 3.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4282) Rota_NSP4 PF01452.11 EMD66139.1 - 0.11 11.8 0.1 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Rotavirus non structural protein Cytochrom_B_N PF00033.14 EMD66139.1 - 0.13 11.5 1.9 0.18 11.1 0.4 2.0 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Wzy_C PF04932.10 EMD66139.1 - 0.57 9.9 7.3 0.47 10.2 0.2 3.1 2 2 1 3 3 3 0 O-Antigen ligase DUF4231 PF14015.1 EMD66139.1 - 0.6 10.1 6.4 0.27 11.2 0.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4131 PF13567.1 EMD66139.1 - 1.4 8.3 9.4 9.9 5.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PrgI PF12666.2 EMD66139.1 - 3.3 7.9 11.6 2.7 8.2 0.2 3.8 4 0 0 4 4 4 0 PrgI family protein DUF3446 PF11928.3 EMD66140.1 - 0.056 13.6 2.6 0.1 12.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) CDP-OH_P_transf PF01066.16 EMD66141.1 - 7e-19 68.0 3.0 7e-19 68.0 2.1 1.8 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DEAD PF00270.24 EMD66142.1 - 2.5e-46 157.2 0.1 5.8e-46 156.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD66142.1 - 1.6e-25 88.7 0.0 6.1e-25 86.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EMD66142.1 - 8.9e-06 24.3 0.9 1.6e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) MCPsignal PF00015.16 EMD66142.1 - 0.0013 18.3 1.5 0.0033 16.9 1.0 1.7 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_22 PF13401.1 EMD66142.1 - 0.0092 16.1 0.1 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Amidohydro_2 PF04909.9 EMD66144.1 - 2.2e-23 83.2 0.1 3e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EMD66147.1 - 2.7e-10 39.4 11.5 6.7e-10 38.2 8.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 EMD66147.1 - 0.07 12.6 0.2 0.28 10.6 0.1 2.1 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain FAD_binding_3 PF01494.14 EMD66148.1 - 2.4e-05 23.5 1.2 0.27 10.2 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain Peptidase_S9 PF00326.16 EMD66148.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyr_redox PF00070.22 EMD66148.1 - 0.027 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD66148.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PDZ_1 PF12812.2 EMD66149.1 - 1.9e-59 197.4 0.0 1.1e-35 121.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EMD66149.1 - 4.3e-15 55.7 0.3 7.7e-14 51.7 0.0 2.7 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EMD66149.1 - 3.9e-13 49.0 0.8 1.1e-06 28.4 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 EMD66149.1 - 2.2e-10 40.5 0.0 0.0001 22.3 0.0 3.8 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EMD66149.1 - 7.2e-05 22.4 0.0 0.0002 21.0 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EMD66149.1 - 0.00013 21.7 0.7 0.016 14.9 0.1 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 EMD66149.1 - 0.13 10.6 0.1 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.11 EMD66149.1 - 0.16 11.2 0.2 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Striatin PF08232.7 EMD66150.1 - 0.055 13.7 7.4 0.068 13.4 5.1 1.1 1 0 0 1 1 1 0 Striatin family DUF3355 PF11835.3 EMD66150.1 - 0.071 12.9 1.1 0.093 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Vfa1 PF08432.5 EMD66150.1 - 0.92 9.5 10.7 1.1 9.2 7.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP11 PF06644.6 EMD66150.1 - 1.6 8.2 6.5 1.7 8.0 4.5 1.1 1 0 0 1 1 1 0 ATP11 protein CutC PF03932.9 EMD66151.1 - 1.2e-58 197.7 0.0 1.3e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 CutC family DHO_dh PF01180.16 EMD66151.1 - 0.045 12.7 0.5 0.045 12.7 0.4 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF2183 PF09949.4 EMD66153.1 - 1.9e-19 69.4 0.1 4.1e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Amidase PF01425.16 EMD66154.1 - 2.7e-68 230.8 0.0 3.4e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EMD66154.1 - 3e-35 121.6 0.0 1.2e-34 119.7 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.10 EMD66155.1 - 1e-64 218.7 25.9 1.3e-64 218.4 17.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DVL PF08137.7 EMD66157.1 - 7 6.1 6.3 9.7 5.7 0.7 2.6 2 0 0 2 2 2 0 DVL family SET PF00856.23 EMD66158.1 - 7.1e-06 26.4 0.0 0.00011 22.4 0.0 2.2 1 1 0 1 1 1 1 SET domain Albumin_I PF08027.6 EMD66162.1 - 0.0018 17.9 4.5 0.0021 17.7 3.1 1.1 1 0 0 1 1 1 1 Albumin I Arginase PF00491.16 EMD66163.1 - 1.4e-76 257.4 0.3 1.6e-76 257.2 0.2 1.0 1 0 0 1 1 1 1 Arginase family DUF167 PF02594.11 EMD66164.1 - 3.5e-16 58.8 0.3 5.2e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 WD40 PF00400.27 EMD66166.1 - 2.4e-15 55.7 5.5 0.0005 19.8 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EMD66166.1 - 0.086 10.9 0.0 0.59 8.1 0.0 2.2 3 0 0 3 3 3 0 Nucleoporin Nup120/160 COQ9 PF08511.6 EMD66167.1 - 1.3e-31 107.8 0.1 2e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 COQ9 FRQ PF09421.5 EMD66168.1 - 1.9e-118 396.7 51.5 4.1e-116 389.0 35.7 3.2 1 1 0 1 1 1 1 Frequency clock protein Leu_zip PF15294.1 EMD66168.1 - 0.0082 15.2 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Leucine zipper SCP1201-deam PF14428.1 EMD66168.1 - 4.3 7.0 8.7 0.66 9.6 0.6 3.1 3 0 0 3 3 3 0 SCP1.201-like deaminase Pyr_redox_2 PF07992.9 EMD66169.1 - 3.8e-31 108.5 0.0 1.2e-30 106.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD66169.1 - 4.5e-13 49.3 0.0 3.3e-10 40.2 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD66169.1 - 2.3e-06 27.8 0.0 0.045 13.8 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD66169.1 - 0.06 13.3 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mis14 PF08641.7 EMD66170.1 - 7.4e-07 29.3 4.3 1.4e-06 28.4 2.9 1.4 1 1 0 1 1 1 1 Kinetochore protein Mis14 like RasGAP PF00616.14 EMD66172.1 - 2.2e-55 187.3 1.5 2.3e-55 187.3 0.1 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EMD66172.1 - 6.8e-30 103.6 3.5 6.8e-30 103.6 2.4 2.7 3 0 0 3 3 3 1 RasGAP C-terminus DUF972 PF06156.8 EMD66172.1 - 2 8.7 10.2 8.8 6.7 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Pyridox_oxidase PF01243.15 EMD66174.1 - 1.3e-06 28.3 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HEM4 PF02602.10 EMD66176.1 - 4.5e-38 130.7 0.0 1e-37 129.6 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PAP2 PF01569.16 EMD66177.1 - 1.2e-18 66.9 4.4 2.5e-18 65.9 3.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF2781 PF10914.3 EMD66177.1 - 0.13 12.0 6.3 0.15 11.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) DPM3 PF08285.6 EMD66177.1 - 0.27 11.1 1.9 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1469 PF07332.6 EMD66177.1 - 4.2 7.1 4.9 1.7 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Polysacc_synt_C PF14667.1 EMD66177.1 - 6.3 6.5 7.7 0.61 9.8 0.5 2.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Glyco_hyd_65N_2 PF14498.1 EMD66178.1 - 1e-49 169.3 0.0 1.6e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 EMD66178.1 - 2.5e-05 23.1 0.1 4.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain zf-Mss51 PF13824.1 EMD66179.1 - 5.7e-28 96.5 7.3 1.3e-27 95.4 5.0 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DTW PF03942.10 EMD66179.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 DTW domain zf-MYND PF01753.13 EMD66179.1 - 0.54 10.1 6.1 0.11 12.3 1.6 1.8 2 0 0 2 2 2 0 MYND finger DNA_pol_A_exo1 PF01612.15 EMD66180.1 - 0.022 14.2 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Conotoxin PF02950.12 EMD66181.1 - 0.049 14.4 1.1 0.063 14.0 0.7 1.1 1 0 0 1 1 1 0 Conotoxin NmrA PF05368.8 EMD66182.1 - 7.6e-41 139.8 0.0 1.1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMD66182.1 - 4.4e-14 52.7 0.0 2e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EMD66182.1 - 2.9e-12 46.9 0.0 2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EMD66182.1 - 1.3e-05 25.1 0.0 0.0027 17.5 0.0 3.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 EMD66182.1 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EMD66182.1 - 0.00081 19.0 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 EMD66182.1 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD66182.1 - 0.0044 16.4 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMD66182.1 - 0.0087 16.3 0.1 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMD66182.1 - 0.14 12.0 0.2 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1510 PF07423.6 EMD66184.1 - 0.07 12.4 11.1 0.08 12.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 EMD66184.1 - 0.075 12.1 9.4 0.095 11.8 6.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EMD66184.1 - 0.091 11.2 12.0 0.097 11.1 8.3 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 EMD66184.1 - 0.094 11.1 10.5 0.091 11.2 7.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 EMD66184.1 - 0.16 10.5 4.2 0.16 10.5 2.9 1.1 1 0 0 1 1 1 0 Raftlin Spore_coat_CotO PF14153.1 EMD66184.1 - 0.21 10.9 12.5 0.24 10.8 8.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 EMD66184.1 - 0.23 10.4 4.2 0.3 10.0 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 EMD66184.1 - 0.36 8.4 8.4 0.37 8.4 5.8 1.0 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 EMD66184.1 - 0.37 9.7 16.5 0.43 9.5 11.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EMD66184.1 - 0.6 8.0 12.8 0.69 7.8 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Upf2 PF04050.9 EMD66184.1 - 0.72 9.5 15.6 1.2 8.9 10.8 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Hid1 PF12722.2 EMD66184.1 - 1.1 6.8 3.5 1.1 6.8 2.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 EMD66184.1 - 1.6 8.5 3.3 1.7 8.4 2.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pox_Ag35 PF03286.9 EMD66184.1 - 1.7 8.1 10.3 2.3 7.6 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_polI_A34 PF08208.6 EMD66184.1 - 10 5.7 20.4 16 5.1 14.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Abhydrolase_5 PF12695.2 EMD66185.1 - 9.4e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EMD66185.1 - 0.00025 19.4 0.0 0.00037 18.9 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EMD66185.1 - 0.0037 17.1 0.1 0.0068 16.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 EMD66186.1 - 2.1e-06 27.6 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD66186.1 - 0.0054 16.8 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EMD66186.1 - 0.013 16.0 0.0 0.075 13.6 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.14 EMD66187.1 - 1.1e-45 156.0 0.9 9.9e-45 152.9 0.3 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD66187.1 - 3.1e-27 95.6 0.0 2.7e-26 92.5 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMD66187.1 - 1.7e-07 30.4 0.5 6e-05 22.0 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD66187.1 - 0.00011 22.1 0.1 0.00036 20.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMD66187.1 - 0.00012 21.2 0.1 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD66187.1 - 0.00072 18.5 7.5 0.013 14.3 5.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMD66187.1 - 0.0022 17.1 0.2 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMD66187.1 - 0.0022 17.8 0.1 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD66187.1 - 0.014 14.5 0.5 0.064 12.3 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Abhydrolase_5 PF12695.2 EMD66187.1 - 0.03 14.0 0.1 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family HI0933_like PF03486.9 EMD66187.1 - 0.11 10.9 0.1 0.17 10.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EMD66187.1 - 0.24 10.1 0.0 1 8.1 0.0 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A FYVE PF01363.16 EMD66189.1 - 2.3e-14 53.0 12.1 3.6e-14 52.4 8.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EMD66189.1 - 0.29 11.0 9.6 1.1 9.1 6.3 2.0 1 1 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EMD66189.1 - 0.84 9.5 13.7 0.16 11.8 5.9 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Dus PF01207.12 EMD66190.1 - 7.2e-54 182.7 0.0 1.4e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EMD66190.1 - 0.0083 15.1 0.0 0.02 13.8 0.0 1.6 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DUF849 PF05853.7 EMD66190.1 - 0.052 12.4 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) DUF3626 PF12294.3 EMD66191.1 - 0.047 12.7 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Zn_clus PF00172.13 EMD66192.1 - 1.7e-05 24.5 10.2 3e-05 23.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 EMD66193.1 - 5.6e-27 94.6 0.0 9.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD66193.1 - 1.8e-17 63.9 0.0 3.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMD66193.1 - 8e-08 31.5 0.3 2e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD66193.1 - 3.2e-07 29.1 0.1 0.00011 20.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMD66193.1 - 8.7e-06 25.7 0.1 1.8e-05 24.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD66193.1 - 2.2e-05 23.7 0.2 0.00016 20.9 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMD66193.1 - 5.2e-05 22.4 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD66193.1 - 8.5e-05 21.6 0.1 0.011 14.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD66193.1 - 0.00019 21.3 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD66193.1 - 0.0014 17.7 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EMD66193.1 - 0.004 16.0 0.1 0.0062 15.4 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMD66193.1 - 0.01 15.9 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD66193.1 - 0.015 15.6 0.2 8.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD66193.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DDE_1 PF03184.14 EMD66194.1 - 1.5e-09 37.2 0.0 2.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EMD66194.1 - 2.3e-05 23.8 0.2 3.5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EMD66194.1 - 0.0022 17.8 0.1 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_7 PF02796.10 EMD66194.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase CRAL_TRIO_2 PF13716.1 EMD66194.1 - 0.087 12.7 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CENP-B_N PF04218.8 EMD66194.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain PTR2 PF00854.16 EMD66196.1 - 3.5e-52 177.4 13.1 5.9e-52 176.6 9.1 1.4 1 1 0 1 1 1 1 POT family Helicase_C_2 PF13307.1 EMD66197.1 - 3.6e-55 186.4 0.0 9.6e-55 185.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMD66197.1 - 1.3e-45 154.9 0.0 2.5e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EMD66197.1 - 0.0036 17.1 0.0 1.1 9.0 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.11 EMD66197.1 - 0.069 12.3 0.0 15 4.7 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein DUF624 PF04854.9 EMD66197.1 - 0.18 11.6 0.3 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 MOZ_SAS PF01853.13 EMD66198.1 - 9.2e-64 214.1 0.0 1.8e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family BTB PF00651.26 EMD66198.1 - 1.9e-06 27.8 0.1 5.9e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Acetyltransf_10 PF13673.1 EMD66198.1 - 0.11 12.6 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MoaC PF01967.16 EMD66199.1 - 2.3e-45 153.6 0.2 3.8e-45 152.9 0.1 1.4 1 0 0 1 1 1 1 MoaC family DUF3708 PF12501.3 EMD66199.1 - 0.25 11.1 5.5 0.14 12.0 0.2 2.8 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter NPV_P10 PF05531.7 EMD66199.1 - 1.3 9.2 7.2 4.4 7.6 2.2 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mob_synth_C PF06463.8 EMD66200.1 - 1e-33 115.7 0.0 5.7e-33 113.3 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EMD66200.1 - 1.5e-20 74.0 0.0 3.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMD66200.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMD66200.1 - 0.00034 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain His_Phos_2 PF00328.17 EMD66201.1 - 2.6e-51 174.9 0.0 3.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AA_permease_2 PF13520.1 EMD66202.1 - 1.3e-56 192.0 56.4 1.5e-56 191.7 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD66202.1 - 1.7e-17 62.9 46.8 2.4e-17 62.4 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EMD66203.1 - 3e-26 92.3 0.3 4.2e-26 91.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD66203.1 - 1.7e-21 77.0 0.4 2e-21 76.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD66203.1 - 1.2e-11 44.6 0.2 1.7e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD66203.1 - 0.0059 16.0 0.1 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA PF00004.24 EMD66204.1 - 2.7e-17 63.1 0.0 4.9e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMD66204.1 - 0.00044 20.2 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD66204.1 - 0.00077 19.6 0.2 0.0075 16.4 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EMD66204.1 - 0.023 14.5 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD66204.1 - 0.024 14.3 0.1 0.075 12.7 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EMD66204.1 - 0.029 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMD66204.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMD66204.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.7 EMD66204.1 - 0.11 11.9 1.9 3.9 6.9 0.2 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Torsin PF06309.6 EMD66204.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF4441 PF14536.1 EMD66205.1 - 5.9 6.8 9.8 4.1 7.4 4.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Mtp PF03821.11 EMD66206.1 - 0.0096 15.3 0.9 0.016 14.5 0.6 1.3 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter PalH PF08733.5 EMD66206.1 - 0.042 12.6 3.2 0.072 11.9 2.2 1.3 1 0 0 1 1 1 0 PalH/RIM21 AA_permease_2 PF13520.1 EMD66207.1 - 2e-22 79.3 42.0 1.6e-13 49.9 11.6 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EMD66207.1 - 4.6e-16 58.2 34.2 1.7e-07 29.9 13.4 2.2 1 1 1 2 2 2 2 Amino acid permease DUF1350 PF07082.6 EMD66207.1 - 0.019 14.0 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1350) DASH_Spc34 PF08657.5 EMD66208.1 - 2.4e-51 174.8 0.9 4.7e-50 170.6 0.6 2.1 1 1 0 1 1 1 1 DASH complex subunit Spc34 Acyl-CoA_dh_1 PF00441.19 EMD66208.1 - 1.6e-25 89.9 4.0 3.3e-25 88.9 0.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD66208.1 - 4.2e-13 49.8 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMD66208.1 - 9.1e-08 31.5 0.1 1.9e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD66208.1 - 5.3e-06 26.7 0.0 5.3e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Mnd1 PF03962.10 EMD66208.1 - 0.25 10.9 5.8 0.41 10.2 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family Rpn3_C PF08375.6 EMD66209.1 - 5e-25 87.7 1.4 1.6e-24 86.0 0.9 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EMD66209.1 - 1.5e-22 79.9 1.7 7.5e-22 77.6 0.1 2.8 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EMD66209.1 - 0.0008 19.1 0.8 0.029 14.1 0.3 2.8 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 Clp1 PF06807.9 EMD66209.1 - 0.12 12.0 0.1 8.6 6.0 0.0 2.7 3 0 0 3 3 3 0 Pre-mRNA cleavage complex II protein Clp1 Ank_2 PF12796.2 EMD66210.1 - 7.3e-25 87.1 0.5 4e-12 46.3 0.2 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD66210.1 - 4.6e-19 68.4 1.2 5.6e-07 29.8 0.1 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD66210.1 - 1e-18 66.9 2.9 1.1e-06 28.7 0.2 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD66210.1 - 5.5e-18 63.7 7.2 1.4e-06 27.7 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EMD66210.1 - 8e-14 50.3 2.8 0.0017 18.4 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Abhydrolase_6 PF12697.2 EMD66213.1 - 2.4e-05 24.3 0.0 9.4e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD66213.1 - 0.004 16.7 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EMD66213.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EMD66213.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) zf-C2H2_4 PF13894.1 EMD66215.1 - 1.1e-07 31.6 8.9 0.00036 20.6 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD66215.1 - 7.4e-07 29.1 10.1 0.0057 16.9 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type SAP18 PF06487.7 EMD66216.1 - 2e-40 137.3 0.0 2.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Tubulin_3 PF14881.1 EMD66217.1 - 2.1e-78 261.9 0.0 2.1e-78 261.9 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Prp18 PF02840.10 EMD66217.1 - 1.5e-28 99.4 2.1 1.6e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain Misat_Tub_SegII PF10644.4 EMD66217.1 - 1.5e-21 76.5 0.3 7.2e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain PRP4 PF08799.6 EMD66217.1 - 2e-11 42.9 0.5 2e-11 42.9 0.3 3.3 4 0 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Tubulin PF00091.20 EMD66217.1 - 0.00033 20.5 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain CVNH PF08881.5 EMD66218.1 - 6.1e-33 113.1 0.1 9.1e-33 112.5 0.1 1.3 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 EMD66218.1 - 3.8e-13 49.1 0.0 5.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 EMD66218.1 - 2.3e-07 30.3 24.1 2.3e-07 30.3 16.7 3.3 3 0 0 3 3 3 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMD66218.1 - 0.01 15.4 14.9 0.01 15.4 10.4 2.8 2 1 1 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 EMD66218.1 - 1.1 8.6 12.1 0.21 10.9 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF533) CCDC66 PF15236.1 EMD66218.1 - 1.5 8.4 12.7 2.8 7.5 8.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 TraT PF05818.7 EMD66218.1 - 5.6 6.3 10.9 1.1 8.6 4.6 1.8 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Ferric_reduct PF01794.14 EMD66219.1 - 5.2e-20 71.7 7.0 5.2e-20 71.7 4.9 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMD66219.1 - 2.3e-14 53.5 0.0 2.2e-11 43.8 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD66219.1 - 4.7e-13 48.9 0.0 1.3e-11 44.3 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMD66219.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain AMP-binding PF00501.23 EMD66222.1 - 3e-55 187.3 4.0 9.4e-21 73.6 0.1 4.8 4 1 0 4 4 4 4 AMP-binding enzyme PYNP_C PF07831.8 EMD66222.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain 4HBT_3 PF13622.1 EMD66223.1 - 5.6e-48 163.9 0.1 7.6e-48 163.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMD66223.1 - 5.8e-27 93.9 0.0 8.9e-14 51.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF2040 PF09745.4 EMD66223.1 - 0.24 11.1 2.9 0.43 10.4 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Zn_clus PF00172.13 EMD66224.1 - 1.9e-07 30.8 7.1 4.1e-07 29.8 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD66224.1 - 0.059 12.2 0.1 0.16 10.7 0.0 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain CoA_trans PF01144.18 EMD66225.1 - 7.3e-102 339.1 4.6 8.7e-60 201.5 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EMD66225.1 - 0.00039 20.1 0.9 0.00067 19.3 0.1 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 EMD66226.1 - 3.9e-33 114.6 27.7 3.9e-33 114.6 19.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD66226.1 - 1.8e-06 27.5 1.3 1.8e-06 27.5 0.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2567 PF10821.3 EMD66226.1 - 0.045 13.2 3.7 0.26 10.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2567) Oxidored_q1_C PF01010.14 EMD66226.1 - 0.057 12.9 1.9 0.1 12.0 0.3 2.1 1 1 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Cu-oxidase_3 PF07732.10 EMD66227.1 - 1.5e-43 147.3 1.1 9.3e-43 144.7 0.7 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD66227.1 - 5e-40 136.2 5.8 6.9e-36 122.7 0.8 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EMD66227.1 - 2.9e-31 108.5 0.1 1.2e-30 106.4 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase DUF11 PF01345.13 EMD66227.1 - 0.04 13.9 0.8 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF2407 PF10302.4 EMD66228.1 - 8.3e-05 22.7 0.0 8.3e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMD66228.1 - 0.0003 20.1 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2730 PF10805.3 EMD66228.1 - 0.02 14.6 0.1 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PBP1_TM PF14812.1 EMD66228.1 - 0.059 13.6 0.0 0.059 13.6 0.0 2.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PK_C PF02887.11 EMD66228.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain DDHD PF02862.12 EMD66228.1 - 0.2 11.4 11.0 1.6 8.4 0.8 2.4 2 0 0 2 2 2 0 DDHD domain DUF4407 PF14362.1 EMD66228.1 - 0.22 10.4 14.7 1.2 8.0 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2956 PF11169.3 EMD66228.1 - 1.5 8.8 12.5 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF912 PF06024.7 EMD66228.1 - 4.7 7.3 10.9 0.097 12.7 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MscS_TM PF12794.2 EMD66228.1 - 6.9 5.1 4.6 27 3.2 3.0 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4557 PF15101.1 EMD66228.1 - 8.2 6.2 9.8 25 4.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) PS_Dcarbxylase PF02666.10 EMD66229.1 - 9.2e-82 273.2 0.0 4.1e-81 271.1 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.27 EMD66231.1 - 0.044 13.6 0.0 0.044 13.6 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 EMD66233.1 - 0.00043 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD66233.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD66233.1 - 0.0043 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD66233.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EMD66234.1 - 1.9e-67 225.8 1.4 2.1e-67 225.7 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMD66234.1 - 9.9e-13 47.7 0.0 1.1e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMD66234.1 - 3.9e-12 45.5 1.4 9.2e-07 27.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMD66234.1 - 3.2e-10 39.5 0.0 3.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMD66234.1 - 4.5e-09 36.2 0.1 7.5e-09 35.5 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMD66234.1 - 5.3e-09 35.5 0.0 6.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMD66234.1 - 7.6e-09 36.1 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMD66234.1 - 1e-06 28.3 0.0 8.8e-05 22.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EMD66234.1 - 0.0054 17.5 0.1 0.0076 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMD66234.1 - 0.018 14.2 0.4 0.056 12.7 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.13 EMD66234.1 - 0.038 13.0 0.3 0.19 10.7 0.1 1.9 1 1 0 2 2 2 0 6-phosphofructo-2-kinase PduV-EutP PF10662.4 EMD66234.1 - 0.069 12.6 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EMD66234.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.1 EMD66234.1 - 0.086 13.1 0.2 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EMD66234.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4045 PF13254.1 EMD66235.1 - 9.4e-114 380.9 37.9 9.4e-114 380.9 26.3 4.8 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EMD66235.1 - 0.00011 21.8 0.0 0.23 11.1 0.0 3.2 3 0 0 3 3 3 2 Gelsolin repeat Glyco_hydro_11 PF00457.12 EMD66236.1 - 1.6e-46 157.9 16.7 2e-46 157.6 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ribosomal_L2_C PF03947.13 EMD66237.1 - 1.6e-38 131.4 2.6 2.6e-38 130.7 1.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMD66237.1 - 2.9e-13 49.5 0.2 5.8e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mg_trans_NIPA PF05653.9 EMD66238.1 - 2.4e-105 351.7 13.9 3.3e-105 351.3 9.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Apc4 PF12896.2 EMD66238.1 - 1.1e-56 191.4 1.7 1.1e-56 191.4 1.2 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EMD66238.1 - 3.6e-11 42.3 0.0 1.3e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain EmrE PF13536.1 EMD66238.1 - 2.7e-07 30.7 2.1 2.7e-07 30.7 1.5 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD66238.1 - 0.00059 19.8 7.6 0.00059 19.8 5.3 3.1 2 1 0 2 2 2 1 EamA-like transporter family DUF2420 PF10336.4 EMD66240.1 - 6.2e-11 41.8 0.1 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EMD66241.1 - 1.5e-15 57.0 0.0 2.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMD66241.1 - 5e-08 32.7 0.2 7.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EMD66241.1 - 0.0018 18.4 1.3 0.088 12.9 0.8 2.9 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) DUF1237 PF06824.6 EMD66243.1 - 8.4e-173 574.8 0.0 9.7e-173 574.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Desulfoferrod_N PF06397.7 EMD66244.1 - 0.17 11.2 1.1 0.26 10.7 0.8 1.2 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Glyco_hydro_61 PF03443.9 EMD66246.1 - 1.3e-70 237.6 0.8 1.4e-70 237.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GSu_C4xC__C2xCH PF09698.5 EMD66246.1 - 1.7 8.8 4.5 1.8 8.7 0.6 2.9 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DWNN PF08783.6 EMD66247.1 - 9.4e-23 79.9 0.0 1.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.1 EMD66247.1 - 0.00019 21.3 6.2 0.00019 21.3 4.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.1 EMD66247.1 - 0.00024 20.5 5.9 0.00061 19.2 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.1 EMD66247.1 - 0.00097 18.9 4.8 0.00097 18.9 3.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.3 EMD66247.1 - 0.0016 17.9 1.9 0.0035 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMD66247.1 - 0.0087 15.7 1.6 0.021 14.5 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EMD66247.1 - 0.033 13.7 5.0 0.092 12.3 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EMD66247.1 - 0.04 13.5 5.6 0.085 12.5 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD66247.1 - 0.11 12.4 7.6 0.24 11.3 5.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCHC PF00098.18 EMD66247.1 - 0.14 12.1 2.8 0.54 10.2 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 EMD66247.1 - 5 6.9 10.9 0.18 11.5 3.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Dicty_REP PF05086.7 EMD66247.1 - 6.8 4.3 6.0 0.34 8.5 0.6 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FNIP_N PF14636.1 EMD66247.1 - 7.9 6.9 9.4 6.7 7.1 0.0 3.0 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus Acetyltransf_1 PF00583.19 EMD66248.1 - 5.7e-12 45.4 0.4 1.6e-11 44.0 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMD66248.1 - 8.6e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMD66248.1 - 4.5e-05 23.5 0.0 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD66248.1 - 4.8e-05 23.4 0.1 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD66248.1 - 0.00014 22.0 0.0 0.00058 20.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMD66248.1 - 0.017 15.0 0.1 0.049 13.5 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD66248.1 - 0.018 14.8 0.0 0.049 13.5 0.0 1.8 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EMD66248.1 - 0.072 13.0 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain KAR9 PF08580.5 EMD66251.1 - 5.3e-96 322.4 4.6 5.3e-96 322.4 3.2 2.2 2 1 1 3 3 3 1 Yeast cortical protein KAR9 Snf7 PF03357.16 EMD66251.1 - 0.51 9.6 8.7 0.12 11.7 0.3 3.4 3 1 1 4 4 4 0 Snf7 IncA PF04156.9 EMD66251.1 - 0.64 9.5 7.3 4.9 6.6 5.0 2.3 1 1 1 2 2 2 0 IncA protein HALZ PF02183.13 EMD66251.1 - 8.3 6.2 8.2 1.6 8.5 2.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cas_APE2256 PF09651.5 EMD66252.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Acylphosphatase PF00708.13 EMD66253.1 - 5.4e-28 96.9 0.1 5.8e-28 96.8 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase PTA_PTB PF01515.14 EMD66253.1 - 0.057 12.4 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase AMP-binding PF00501.23 EMD66254.1 - 4.7e-65 219.6 0.0 6.6e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD66254.1 - 3.6e-10 40.6 0.1 1.1e-09 39.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 EMD66254.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Aminotran_3 PF00202.16 EMD66255.1 - 1.1e-84 284.1 0.1 1.4e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.16 EMD66256.1 - 4.9e-45 153.8 0.1 8.9e-45 152.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.14 EMD66256.1 - 0.068 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Fungal_trans PF04082.13 EMD66257.1 - 2.3e-14 52.9 0.1 4.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66257.1 - 0.00018 21.3 9.7 0.00035 20.4 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AOX PF01786.12 EMD66258.1 - 5e-90 300.4 0.3 6.1e-90 300.1 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase GMC_oxred_N PF00732.14 EMD66259.1 - 6e-80 268.5 0.0 8.4e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD66259.1 - 6.9e-35 120.4 0.0 1.8e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD66259.1 - 1.7e-06 27.1 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD66259.1 - 0.0019 17.1 0.1 0.003 16.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMD66259.1 - 0.0026 16.8 0.7 0.099 11.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMD66259.1 - 0.005 15.7 0.2 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMD66259.1 - 0.13 12.1 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD66260.1 - 3e-06 27.2 0.0 2.9e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD66260.1 - 0.0025 17.9 0.1 0.04 13.9 0.1 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD66260.1 - 0.0064 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EMD66260.1 - 0.0064 15.4 0.1 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 EMD66260.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Fungal_trans PF04082.13 EMD66261.1 - 2.6e-19 69.1 0.2 4.4e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66261.1 - 2.3e-07 30.5 8.2 4.7e-07 29.6 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_9 PF14604.1 EMD66262.1 - 6.7e-09 35.1 0.0 1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMD66262.1 - 1.9e-06 27.1 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMD66262.1 - 2.4e-06 26.9 0.0 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.6 EMD66262.1 - 0.00041 19.9 0.1 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 EMD66262.1 - 0.075 12.3 0.2 0.17 11.2 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Chordopox_A13L PF05961.6 EMD66262.1 - 0.34 10.8 0.0 0.69 9.8 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Cnd2 PF05786.9 EMD66262.1 - 1.4 7.2 4.5 2.1 6.7 3.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CorA PF01544.13 EMD66263.1 - 1.8e-10 40.3 1.0 3.5e-10 39.3 0.7 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RasGEF PF00617.14 EMD66264.1 - 1.3e-44 152.1 0.2 2.2e-44 151.4 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMD66264.1 - 3.4e-12 46.3 0.3 7.2e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF3445 PF11927.3 EMD66265.1 - 6.8e-77 258.2 0.0 9e-77 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 EMD66266.1 - 2.6e-82 277.0 22.0 3.1e-82 276.8 15.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT PF02366.13 EMD66266.1 - 3.9e-06 26.4 7.3 3.9e-06 26.4 5.1 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Gar1 PF04410.9 EMD66267.1 - 3.5e-39 133.7 2.9 3.5e-39 133.7 2.0 4.8 3 1 0 4 4 4 1 Gar1/Naf1 RNA binding region PP2C PF00481.16 EMD66268.1 - 4.1e-50 170.5 0.0 6.8e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EMD66268.1 - 9.6e-49 162.3 48.3 8e-07 28.5 0.5 13.4 8 5 8 16 16 16 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD66268.1 - 4.9e-40 135.1 48.0 5.5e-10 38.8 0.2 10.0 4 3 10 14 14 14 12 Leucine rich repeat Guanylate_cyc PF00211.15 EMD66268.1 - 1.3e-31 109.3 0.0 5.2e-31 107.4 0.0 1.8 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EMD66268.1 - 2.2e-23 78.6 51.3 0.061 13.3 0.0 19.4 17 2 1 18 18 17 9 Leucine Rich Repeat RA PF00788.18 EMD66268.1 - 2e-13 50.6 0.4 7.5e-12 45.5 0.1 2.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EMD66268.1 - 2.9e-09 35.6 47.3 0.048 13.8 0.2 16.3 17 1 1 18 18 17 2 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 EMD66268.1 - 1.1e-06 27.8 0.2 4.1e-06 26.0 0.1 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.1 EMD66268.1 - 8.5e-05 22.1 5.0 0.17 11.4 0.1 3.4 3 0 0 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.1 EMD66268.1 - 0.0003 20.4 0.0 2.6 7.7 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EMD66268.1 - 0.15 12.2 43.8 3.7 7.9 0.0 14.6 17 2 1 18 18 18 0 Leucine Rich repeat Indigoidine_A PF04227.7 EMD66269.1 - 5e-118 393.5 0.3 7.7e-118 392.9 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EMD66269.1 - 4.7e-24 85.0 0.3 3.7e-12 45.9 0.0 2.8 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMD66269.1 - 0.00018 20.7 0.1 0.039 13.1 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase Ribophorin_I PF04597.9 EMD66270.1 - 1e-153 511.9 0.1 1.2e-153 511.7 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I ATP_bind_2 PF03668.10 EMD66271.1 - 0.00092 18.3 0.0 0.00099 18.2 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family Peptidase_M36 PF02128.10 EMD66272.1 - 0.15 10.9 0.1 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Zn_clus PF00172.13 EMD66273.1 - 4.5e-09 36.0 13.1 8.3e-09 35.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD66273.1 - 0.00033 19.6 0.0 0.00067 18.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EMD66276.1 - 2.2e-48 164.9 0.0 2.9e-47 161.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 CinA PF02464.12 EMD66277.1 - 1.9e-35 121.6 2.9 2.2e-35 121.3 2.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein DnaJ PF00226.26 EMD66279.1 - 3.2e-26 90.8 3.8 5.6e-26 90.0 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMD66279.1 - 3.7e-15 55.7 16.2 6.3e-15 54.9 11.3 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EMD66279.1 - 4.6e-12 45.6 0.0 1.7e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EMD66279.1 - 0.011 15.3 8.7 0.12 12.0 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EMD66279.1 - 0.037 14.3 6.6 0.47 10.8 0.1 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar Stc1 PF12898.2 EMD66279.1 - 6.2 6.9 9.0 1.9 8.5 0.6 2.5 1 1 1 2 2 2 0 Stc1 domain Ribosomal_S17 PF00366.15 EMD66280.1 - 3e-06 27.1 2.0 6.2e-06 26.1 0.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S17 Cnd1_N PF12922.2 EMD66281.1 - 8.2e-58 194.8 0.2 2.7e-57 193.0 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EMD66281.1 - 2.9e-56 190.1 6.6 1.4e-50 171.5 0.3 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMD66281.1 - 6.9e-09 35.8 14.4 0.00091 19.4 0.0 7.6 6 3 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EMD66281.1 - 2.2e-05 24.1 12.3 0.4 10.8 0.0 7.7 8 1 1 9 9 9 2 HEAT repeat DUF2435 PF10363.4 EMD66281.1 - 0.00035 20.4 0.3 0.5 10.2 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EMD66281.1 - 0.0013 18.5 1.1 5.3 7.1 0.2 4.5 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EMD66281.1 - 0.014 15.8 8.7 7 7.2 0.2 6.5 7 0 0 7 7 7 0 HEAT-like repeat p450 PF00067.17 EMD66281.1 - 0.13 10.7 2.8 0.15 10.5 0.2 2.2 2 1 1 3 3 3 0 Cytochrome P450 Pkinase PF00069.20 EMD66282.1 - 3.7e-44 150.8 0.0 8.7e-43 146.3 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66282.1 - 3.5e-12 45.9 0.0 5.7e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMD66282.1 - 2.4e-05 23.4 0.0 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMD66282.1 - 0.00057 19.6 0.9 0.035 13.8 0.0 3.3 2 1 2 4 4 4 1 Phosphotransferase enzyme family Pro-kuma_activ PF09286.6 EMD66283.1 - 2.7e-41 140.9 0.0 9.2e-41 139.2 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain RNA_pol_Rpb2_6 PF00562.23 EMD66284.1 - 4.7e-113 377.8 0.2 6.2e-113 377.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMD66284.1 - 8.1e-33 113.0 0.0 1.2e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EMD66284.1 - 1.1e-24 86.1 0.0 2.5e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 EMD66284.1 - 1.9e-23 81.9 0.0 4.3e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EMD66284.1 - 2e-22 79.5 0.0 3.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMD66284.1 - 1.6e-14 53.9 0.0 6e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EMD66284.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 EMD66284.1 - 0.0024 17.7 0.6 0.0048 16.7 0.4 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.16 EMD66285.1 - 1.6e-44 151.2 0.0 1.9e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMD66285.1 - 2.9e-18 65.7 0.0 3.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD66285.1 - 5.8e-11 42.9 0.0 8.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EMD66285.1 - 2.5e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMD66285.1 - 8e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMD66285.1 - 8.6e-06 25.0 0.0 9.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMD66285.1 - 5.2e-05 22.7 0.0 0.00095 18.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EMD66285.1 - 5.3e-05 22.0 0.2 0.00015 20.6 0.0 1.6 1 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EMD66285.1 - 0.0086 15.9 0.0 0.06 13.1 0.1 1.9 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EMD66285.1 - 0.0091 15.2 0.3 0.022 14.0 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EMD66285.1 - 0.064 12.7 0.0 0.31 10.5 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RCR PF12273.3 EMD66287.1 - 1e-26 93.9 6.1 1.3e-26 93.7 4.2 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EMD66287.1 - 8.6e-07 28.8 0.4 9.9e-07 28.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Shisa PF13908.1 EMD66287.1 - 0.0056 16.8 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rhabdo_glycop PF00974.13 EMD66287.1 - 0.011 14.0 0.9 0.014 13.6 0.6 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein OSTbeta PF15048.1 EMD66287.1 - 0.035 14.1 0.1 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2868 PF11067.3 EMD66287.1 - 0.04 13.0 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF3328 PF11807.3 EMD66287.1 - 0.044 13.4 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) GP41 PF00517.12 EMD66287.1 - 0.058 12.9 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Tetraspannin PF00335.15 EMD66287.1 - 0.27 10.4 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF998 PF06197.8 EMD66287.1 - 0.43 9.8 4.5 0.25 10.6 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Synaptobrevin PF00957.16 EMD66287.1 - 0.58 9.7 2.1 0.85 9.2 1.5 1.2 1 0 0 1 1 1 0 Synaptobrevin Coatomer_WDAD PF04053.9 EMD66288.1 - 3.3e-148 494.1 0.1 5.6e-148 493.4 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EMD66288.1 - 2.3e-80 270.2 0.0 3.2e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EMD66288.1 - 3.7e-48 159.7 12.6 1.5e-08 34.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMD66288.1 - 0.007 14.5 5.8 0.63 8.0 0.0 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EMD66288.1 - 0.18 11.3 3.3 0.18 11.4 0.1 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS Cupin_1 PF00190.17 EMD66290.1 - 9.5e-09 34.8 0.5 2.3e-08 33.6 0.3 1.5 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMD66290.1 - 0.13 11.7 0.1 0.33 10.4 0.1 1.8 1 1 0 1 1 1 0 Cupin domain tRNA-synt_1b PF00579.20 EMD66291.1 - 3.3e-62 210.2 0.0 4.9e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MscS_porin PF12795.2 EMD66291.1 - 0.012 14.9 0.4 0.022 14.0 0.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ATP-synt_B PF00430.13 EMD66291.1 - 0.023 14.5 3.2 0.053 13.3 2.2 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) THOC7 PF05615.8 EMD66291.1 - 0.025 14.8 0.9 0.17 12.1 0.2 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Sugarporin_N PF11471.3 EMD66291.1 - 0.066 12.8 2.5 0.23 11.1 1.7 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension LCAT PF02450.10 EMD66292.1 - 2.2e-98 329.7 0.0 2.7e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 EMD66292.1 - 0.006 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Tobravirus_2B PF05271.6 EMD66292.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Tobravirus 2B protein Lipase_2 PF01674.13 EMD66292.1 - 0.15 11.3 0.1 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.19 EMD66293.1 - 1.3e-17 63.5 0.0 2.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD66293.1 - 3.8e-11 43.1 0.0 5.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD66293.1 - 1.1e-10 41.1 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMD66293.1 - 1.4e-10 41.4 0.0 1.8e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD66293.1 - 2.8e-10 40.1 0.0 4.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMD66293.1 - 3.9e-09 36.5 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD66293.1 - 2.3e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EMD66293.1 - 0.001 17.9 0.1 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 EMD66293.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EMD66293.1 - 0.0074 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PaaA_PaaC PF05138.7 EMD66294.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Peptidase_S15 PF02129.13 EMD66295.1 - 0.00029 20.3 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PhyH PF05721.8 EMD66296.1 - 6.5e-07 29.5 0.0 1.7e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EMD66296.1 - 8.6e-06 24.4 0.8 0.082 11.3 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EMD66297.1 - 3e-11 42.7 0.1 5.7e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66297.1 - 1.3e-05 25.0 13.9 2.6e-05 24.0 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMD66298.1 - 8.1e-23 80.6 26.7 8.1e-23 80.6 18.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD66298.1 - 3.5e-06 25.8 25.5 1.4e-05 23.9 17.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TFIID_20kDa PF03847.8 EMD66299.1 - 1.9e-22 79.3 0.2 3.6e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Exo_endo_phos PF03372.18 EMD66299.1 - 5.2e-17 62.5 0.0 1.1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 EMD66299.1 - 0.0072 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Luciferase catalytic domain WD40 PF00400.27 EMD66300.1 - 4.5e-71 232.4 22.1 2.2e-15 55.8 0.3 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMD66300.1 - 1.5e-07 31.3 0.0 0.0009 18.9 0.0 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMD66300.1 - 5.7e-06 24.7 4.5 0.012 13.7 0.2 4.6 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD66300.1 - 1.3e-05 24.1 1.3 0.02 13.6 0.1 3.9 2 2 1 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 EMD66300.1 - 0.0016 16.7 0.0 0.0072 14.6 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) PD40 PF07676.7 EMD66300.1 - 0.0054 16.3 0.2 8.4 6.1 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EMD66300.1 - 0.011 14.6 0.2 2.7 6.7 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.4 EMD66300.1 - 0.95 8.8 2.8 22 4.4 0.0 3.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature RrnaAD PF00398.15 EMD66301.1 - 2.1e-59 200.7 0.0 2.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMD66301.1 - 4.5e-11 42.8 0.0 9.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66301.1 - 2.5e-07 31.2 0.0 4.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD66301.1 - 7.5e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMD66301.1 - 2.4e-05 23.9 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMD66301.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD66301.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD66301.1 - 0.0052 17.2 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMD66301.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EMD66301.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.12 EMD66301.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 EMD66301.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ada3 PF10198.4 EMD66301.1 - 0.86 9.3 4.3 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 AP_endonuc_2 PF01261.19 EMD66303.1 - 6.9e-32 110.4 0.4 1.1e-31 109.8 0.3 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 EMD66304.1 - 2.3e-08 33.8 9.4 5.5e-08 32.5 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.17 EMD66305.1 - 1.2e-10 40.9 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMD66305.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Cupin domain DUF1191 PF06697.7 EMD66307.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Proteasome PF00227.21 EMD66309.1 - 8.5e-49 165.4 0.2 1e-48 165.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EMD66309.1 - 0.032 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) PHD PF00628.24 EMD66310.1 - 5.4e-09 35.5 6.8 5.4e-09 35.5 4.7 2.3 2 0 0 2 2 2 1 PHD-finger JmjC PF02373.17 EMD66310.1 - 1.2e-08 35.2 0.0 1.6e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EMD66310.1 - 2.9e-08 33.5 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Dickkopf_N PF04706.7 EMD66310.1 - 0.19 11.9 12.8 0.084 13.0 0.3 2.9 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF1423 PF07227.6 EMD66310.1 - 0.38 9.3 1.2 0.59 8.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) PHD_2 PF13831.1 EMD66310.1 - 1.2 8.4 10.1 0.27 10.5 3.3 2.6 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 EMD66310.1 - 1.5 8.0 7.7 0.18 11.0 1.5 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RRM_1 PF00076.17 EMD66311.1 - 1.8e-14 53.0 0.2 6.7e-14 51.2 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66311.1 - 2.8e-10 40.0 0.1 5.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66311.1 - 3.2e-09 36.4 0.1 4.9e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPCD PF14913.1 EMD66311.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DPCD protein family DUF1772 PF08592.6 EMD66312.1 - 1.5 8.5 5.0 6.7 6.4 3.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DRIM PF07539.7 EMD66313.1 - 3.1e-39 133.6 0.1 1.3e-38 131.5 0.1 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis CwfJ_C_2 PF04676.9 EMD66314.1 - 2e-23 82.7 2.7 4.6e-23 81.5 1.9 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EMD66314.1 - 8.3e-22 77.1 0.0 1.9e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 HIT PF01230.18 EMD66314.1 - 0.073 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 HIT domain MFS_1 PF07690.11 EMD66315.1 - 8.4e-32 110.2 28.3 1.3e-31 109.6 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 EMD66315.1 - 1.2 8.3 3.6 0.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Gti1_Pac2 PF09729.4 EMD66316.1 - 7.4e-51 172.3 0.7 4.2e-49 166.6 0.5 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family p450 PF00067.17 EMD66317.1 - 5.7e-75 252.6 0.0 8.1e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EMD66319.1 - 4.9e-06 26.3 9.9 9.2e-06 25.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 EMD66320.1 - 1e-130 436.2 8.8 1.2e-130 435.9 6.1 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMD66320.1 - 1.3e-39 135.4 1.8 1.5e-39 135.2 0.6 1.6 2 0 0 2 2 2 1 ML-like domain EphA2_TM PF14575.1 EMD66320.1 - 1.8 9.0 0.0 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4519 PF15012.1 EMD66322.1 - 0.095 12.6 1.4 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Es2 PF09751.4 EMD66322.1 - 0.53 9.6 4.0 0.59 9.4 2.8 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 Glyco_hydro_cc PF11790.3 EMD66323.1 - 6.2e-68 228.7 2.1 7.4e-68 228.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_81 PF03639.8 EMD66324.1 - 1.6e-196 654.4 13.0 1.9e-196 654.2 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 PGAP1 PF07819.8 EMD66324.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pertactin PF03212.9 EMD66324.1 - 0.12 12.1 3.5 0.78 9.4 0.0 3.2 3 0 0 3 3 3 0 Pertactin Ammonium_transp PF00909.16 EMD66327.1 - 2.1e-115 385.4 28.5 2.4e-115 385.2 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Clat_adaptor_s PF01217.15 EMD66329.1 - 3.8e-56 188.7 1.2 4.4e-56 188.5 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec23_trunk PF04811.10 EMD66330.1 - 2.8e-54 184.0 0.0 5.4e-54 183.1 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMD66330.1 - 1.1e-26 92.2 0.0 2.1e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMD66330.1 - 1.3e-17 64.0 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMD66330.1 - 6.7e-17 60.7 3.3 6.7e-17 60.7 2.3 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMD66330.1 - 2.4e-07 30.3 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 EMD66330.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Ribosomal_L18e PF00828.14 EMD66331.1 - 4.6e-33 114.3 0.2 6.3e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF605 PF04652.11 EMD66332.1 - 0.18 11.1 19.5 0.23 10.8 13.5 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EMD66332.1 - 1.8 6.6 15.7 2.2 6.4 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GatB_N PF02934.10 EMD66333.1 - 7.5e-99 330.2 0.0 1.1e-98 329.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EMD66333.1 - 9.8e-16 57.7 0.1 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 GatB domain Inositol_P PF00459.20 EMD66334.1 - 6.5e-58 196.1 0.0 8.2e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family RRM_1 PF00076.17 EMD66335.1 - 2.8e-16 58.8 0.0 4.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66335.1 - 1.8e-09 37.4 0.0 3.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66335.1 - 0.0014 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.14 EMD66336.1 - 1e-133 445.0 0.0 1.3e-133 444.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMD66336.1 - 1.5e-49 167.9 0.1 2.2e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD66336.1 - 0.021 14.8 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AD PF09793.4 EMD66337.1 - 5.5e-24 83.8 0.3 8.1e-24 83.2 0.2 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Ank PF00023.25 EMD66338.1 - 3.8e-14 51.6 1.6 7.6e-05 22.3 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMD66338.1 - 6e-14 52.1 0.1 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD66338.1 - 9.1e-13 48.3 0.2 2.5e-06 27.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD66338.1 - 1e-06 28.7 0.3 0.52 10.6 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD66338.1 - 9.5e-06 25.3 1.3 0.59 10.5 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat LisH PF08513.6 EMD66338.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 LisH HET PF06985.6 EMD66339.1 - 1.1e-24 87.1 0.0 1.8e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UDP-g_GGTase PF06427.6 EMD66340.1 - 1.4e-63 214.0 0.0 1.1e-62 211.0 0.0 2.3 3 0 0 3 3 3 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMD66340.1 - 0.00029 20.2 0.8 0.00083 18.7 0.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF3431 PF11913.3 EMD66341.1 - 6.8e-88 293.8 0.2 8.5e-88 293.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DNA_methylase PF00145.12 EMD66342.1 - 3.8e-25 88.7 0.0 4.5e-24 85.1 0.0 2.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EMD66342.1 - 1.4e-10 40.9 0.0 0.00029 20.5 0.0 2.7 3 0 0 3 3 3 2 BAH domain Amidohydro_4 PF13147.1 EMD66343.1 - 6.1e-09 36.3 0.0 8.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EMD66343.1 - 1e-07 31.8 0.0 4.3e-07 29.7 0.0 1.6 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD66343.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family DENN PF02141.16 EMD66344.1 - 0.0014 18.3 0.5 0.019 14.6 0.3 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 EMD66344.1 - 0.0054 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Vac14_Fig4_bd PF11916.3 EMD66345.1 - 2e-81 271.5 7.2 2e-81 271.5 5.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EMD66345.1 - 9.2e-47 157.4 0.1 9.1e-44 147.8 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EMD66345.1 - 2.6e-10 39.4 2.1 0.00022 21.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EMD66345.1 - 1.5e-08 34.8 1.0 0.0021 18.3 0.0 4.9 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EMD66345.1 - 2.7e-08 34.0 0.9 0.0059 17.0 0.0 5.6 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 EMD66345.1 - 0.0003 20.6 1.3 0.68 9.7 0.0 4.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EMD66345.1 - 0.0066 16.2 0.0 11 5.9 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Vma12 PF11712.3 EMD66346.1 - 2.8e-36 124.3 0.0 7e-36 123.0 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase polyprenyl_synt PF00348.12 EMD66347.1 - 8.8e-53 178.7 0.1 1.3e-49 168.3 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase DUF3659 PF12396.3 EMD66347.1 - 0.066 12.8 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Thymosin PF01290.15 EMD66347.1 - 0.16 11.6 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Thymosin beta-4 family His_biosynth PF00977.16 EMD66348.1 - 1.2e-46 158.8 0.3 5.2e-46 156.7 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EMD66348.1 - 8.3e-30 103.6 0.0 1.3e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EMD66348.1 - 1.4e-11 44.4 0.0 3.2e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMD66348.1 - 8.9e-09 35.1 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EMD66348.1 - 0.0034 16.8 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 S4 PF01479.20 EMD66349.1 - 4.9e-11 41.8 0.0 8.4e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EMD66349.1 - 5.1e-11 42.7 0.3 8e-11 42.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain HET PF06985.6 EMD66350.1 - 1.4e-33 116.0 0.1 2.6e-33 115.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRI12 PF06609.8 EMD66351.1 - 7.8e-59 199.4 21.2 1.1e-58 198.9 14.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMD66351.1 - 8.7e-19 67.4 40.8 8.7e-19 67.4 28.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD66351.1 - 7.3e-13 47.8 2.8 7.3e-13 47.8 2.0 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter YrhK PF14145.1 EMD66351.1 - 1.4 8.5 11.5 3.1 7.5 0.0 3.4 3 1 0 3 3 3 0 YrhK-like protein Grp1_Fun34_YaaH PF01184.14 EMD66352.1 - 4.1e-19 68.7 25.7 5.4e-19 68.3 17.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2721 PF11026.3 EMD66352.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2721) Cu-oxidase_3 PF07732.10 EMD66353.1 - 4.5e-44 148.9 5.5 7.7e-40 135.2 1.1 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD66353.1 - 4e-41 139.7 9.6 2.2e-34 117.9 0.3 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EMD66353.1 - 7.3e-37 126.7 0.3 2.2e-36 125.1 0.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cupin_5 PF06172.6 EMD66354.1 - 2.8e-34 118.0 0.0 4.2e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) IU_nuc_hydro PF01156.14 EMD66355.1 - 1.5e-20 73.6 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Sugar_tr PF00083.19 EMD66356.1 - 8.1e-94 314.7 22.9 9.8e-94 314.4 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD66356.1 - 2.2e-20 72.6 33.3 3.2e-17 62.2 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD66356.1 - 0.0092 14.2 1.1 0.019 13.1 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1443 PF07280.6 EMD66356.1 - 0.03 13.9 0.1 0.11 12.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) PRP1_N PF06424.7 EMD66359.1 - 5.3e-52 175.6 6.7 5.3e-52 175.6 4.7 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EMD66359.1 - 5.5e-25 85.5 16.9 0.0049 17.3 0.0 13.9 6 3 8 15 15 14 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMD66359.1 - 4.6e-21 74.9 6.9 0.00097 19.4 0.0 10.0 8 2 1 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD66359.1 - 9.1e-18 64.4 4.4 0.016 15.8 0.0 8.3 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD66359.1 - 7.1e-11 41.5 4.0 4.7e-06 26.1 0.0 7.2 6 4 3 9 9 9 2 TPR repeat TPR_2 PF07719.12 EMD66359.1 - 6.7e-10 38.1 2.1 13 6.0 0.0 10.8 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD66359.1 - 3.3e-06 26.4 0.0 29 4.7 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD66359.1 - 3e-05 23.4 0.1 1.3 8.7 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD66359.1 - 0.00036 20.0 0.1 2.3 8.2 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66359.1 - 0.0005 19.9 9.0 1.4 8.9 0.0 7.0 9 1 1 10 10 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD66359.1 - 0.0029 17.6 0.0 64 4.1 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF3808 PF10300.4 EMD66359.1 - 0.017 13.7 0.2 0.2 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) ChAPs PF09295.5 EMD66359.1 - 0.07 11.8 3.8 0.62 8.7 0.1 3.3 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PsbK PF02533.10 EMD66359.1 - 0.15 12.0 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component RhoGEF PF00621.15 EMD66359.1 - 0.15 11.8 0.9 0.43 10.4 0.6 1.7 1 0 0 1 1 1 0 RhoGEF domain ABC_membrane PF00664.18 EMD66360.1 - 1.1e-38 133.2 11.9 1.5e-38 132.7 8.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMD66360.1 - 3.1e-36 124.6 0.0 6.9e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMD66360.1 - 1.6e-07 31.5 0.0 0.0067 16.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EMD66360.1 - 1.1e-06 27.9 0.0 0.00032 19.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMD66360.1 - 1.7e-05 24.8 0.0 5.3e-05 23.2 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.1 EMD66360.1 - 3.3e-05 23.7 0.0 0.0021 17.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD66360.1 - 4.2e-05 24.3 0.0 9.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD66360.1 - 0.0004 19.8 0.0 0.0017 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMD66360.1 - 0.001 19.2 0.1 0.013 15.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMD66360.1 - 0.0023 18.1 0.0 0.019 15.1 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMD66360.1 - 0.0026 17.2 0.5 0.0077 15.7 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EMD66360.1 - 0.003 17.0 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EMD66360.1 - 0.0073 16.6 0.0 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD66360.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EMD66360.1 - 0.012 15.4 0.1 0.21 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EMD66360.1 - 0.017 14.7 0.1 2 8.0 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 EMD66360.1 - 0.019 14.0 0.0 0.064 12.3 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.20 EMD66360.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EMD66360.1 - 0.028 13.9 0.0 0.11 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EMD66360.1 - 0.03 14.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EMD66360.1 - 0.037 13.9 0.1 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMD66360.1 - 0.046 14.0 0.4 0.1 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EMD66360.1 - 0.054 13.4 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.10 EMD66360.1 - 0.059 12.0 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TPR_1 PF00515.23 EMD66360.1 - 0.073 12.7 0.7 0.23 11.1 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_24 PF13479.1 EMD66360.1 - 0.13 11.8 1.9 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AIM24 PF01987.12 EMD66361.1 - 1.5e-44 151.9 0.0 1.9e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF1983 PF09327.6 EMD66361.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1983) DUF3554 PF12074.3 EMD66362.1 - 1.9e-71 241.2 10.3 1.9e-71 241.2 7.2 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EMD66362.1 - 5.1e-32 110.0 49.4 1.5e-07 31.6 0.0 15.5 6 3 9 15 15 15 11 HEAT repeats HEAT PF02985.17 EMD66362.1 - 5.3e-32 107.0 31.9 0.12 12.5 0.0 19.8 21 0 0 21 21 21 9 HEAT repeat HEAT_EZ PF13513.1 EMD66362.1 - 6e-32 109.3 58.5 4.6e-06 26.9 0.0 21.4 15 3 9 24 24 24 9 HEAT-like repeat ParcG PF10274.4 EMD66362.1 - 7.5e-11 42.2 3.3 0.019 14.8 0.0 6.2 5 0 0 5 5 5 3 Parkin co-regulated protein Cnd1 PF12717.2 EMD66362.1 - 3.3e-10 40.0 0.1 0.64 9.8 0.1 8.1 6 2 0 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EMD66362.1 - 6.8e-09 35.4 0.0 0.0072 15.7 0.0 6.1 5 1 1 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EMD66362.1 - 7.7e-09 35.8 0.1 19 5.7 0.0 8.8 8 3 2 10 10 10 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EMD66362.1 - 0.00012 22.0 0.0 0.64 10.0 0.0 5.3 6 0 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation SAGA-Tad1 PF12767.2 EMD66363.1 - 5.9e-48 163.7 0.0 9.8e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 EMD66364.1 - 5.7e-26 89.4 21.0 5.1e-09 35.6 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat DLH PF01738.13 EMD66365.1 - 2.5e-26 92.3 0.0 2.9e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMD66365.1 - 4.1e-07 29.8 0.0 5.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD66365.1 - 0.00011 22.1 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD66365.1 - 0.11 11.6 0.0 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Antitoxin-MazE PF04014.13 EMD66366.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE WD40 PF00400.27 EMD66367.1 - 2.8e-55 182.3 24.1 2e-08 33.7 0.9 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat PQQ_3 PF13570.1 EMD66367.1 - 0.00016 21.7 11.9 0.23 11.7 0.0 6.9 7 0 0 7 7 7 2 PQQ-like domain PQQ PF01011.16 EMD66367.1 - 0.0011 18.4 2.0 3.8 7.2 0.0 4.5 4 0 0 4 4 4 2 PQQ enzyme repeat Hira PF07569.6 EMD66367.1 - 0.038 13.1 0.1 0.081 12.1 0.1 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split SPATA25 PF15218.1 EMD66369.1 - 0.077 12.4 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 zf-H2C2_5 PF13909.1 EMD66369.1 - 0.2 11.9 2.4 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EMD66369.1 - 0.3 11.5 7.5 3.2 8.2 1.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger COesterase PF00135.23 EMD66370.1 - 2.6e-96 323.4 0.0 3.2e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD66370.1 - 4.3e-06 26.4 0.1 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EMD66371.1 - 3.9e-33 114.6 37.5 5.3e-33 114.1 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily KR PF08659.5 EMD66372.1 - 5.2e-06 26.2 0.6 1.6e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 KR domain DUF359 PF04019.7 EMD66372.1 - 0.057 12.7 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) DUF1904 PF08921.6 EMD66372.1 - 0.07 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Peptidase_S8 PF00082.17 EMD66373.1 - 4.7e-48 163.7 0.0 9.6e-48 162.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMD66373.1 - 1.5e-09 38.2 0.1 4.5e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) NPCBM_assoc PF10633.4 EMD66373.1 - 0.011 15.7 1.1 0.039 13.9 0.2 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FlgD_ig PF13860.1 EMD66373.1 - 0.064 12.9 0.0 0.58 9.9 0.0 2.6 3 0 0 3 3 3 0 FlgD Ig-like domain FAD_binding_3 PF01494.14 EMD66374.1 - 6.6e-27 94.4 0.0 4.1e-26 91.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD66374.1 - 6.9e-06 25.1 0.0 0.01 14.7 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD66374.1 - 2.4e-05 24.2 0.1 5.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMD66374.1 - 0.00042 19.2 0.0 0.0014 17.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 EMD66374.1 - 0.00075 18.2 0.6 0.17 10.4 0.0 2.4 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 EMD66374.1 - 0.00082 17.9 0.1 0.023 13.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMD66374.1 - 0.0029 17.5 0.1 0.0095 15.8 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD66374.1 - 0.0035 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMD66374.1 - 0.012 16.0 0.4 0.12 12.8 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMD66374.1 - 0.021 14.4 0.1 0.089 12.3 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EMD66374.1 - 0.032 13.1 0.0 0.67 8.8 0.0 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMD66374.1 - 0.052 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EMD66374.1 - 0.17 10.7 0.1 13 4.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EMD66375.1 - 3.3e-13 49.9 0.0 9.1e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD66375.1 - 2.9e-07 30.5 0.0 6.2e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD66375.1 - 2.7e-06 27.1 0.1 1.1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMD66375.1 - 1.3e-05 25.3 0.1 0.00011 22.2 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMD66375.1 - 0.0012 18.1 0.1 0.0021 17.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMD66375.1 - 0.0067 15.8 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMD66375.1 - 0.025 14.5 0.1 0.076 13.0 0.0 1.8 2 1 1 3 3 3 0 TrkA-N domain 3Beta_HSD PF01073.14 EMD66375.1 - 0.035 12.7 0.0 0.065 11.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MBOAT_2 PF13813.1 EMD66376.1 - 3.6e-25 87.8 2.8 1.1e-24 86.2 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.3 EMD66377.1 - 5.8e-40 137.0 8.7 7.8e-37 126.7 3.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66377.1 - 1e-06 28.5 9.7 1e-06 28.5 6.7 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiA PF01040.13 EMD66378.1 - 5.8e-32 110.9 20.8 7.7e-32 110.5 14.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ketoacyl-synt PF00109.21 EMD66379.1 - 7.5e-62 209.0 0.8 1.7e-61 207.8 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD66379.1 - 1.2e-46 159.5 0.3 3.8e-46 157.8 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD66379.1 - 4.8e-35 119.9 0.3 1.3e-34 118.6 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EMD66379.1 - 4.5e-31 108.8 0.0 9.1e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EMD66379.1 - 8.9e-18 64.4 0.0 2.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EMD66379.1 - 2.4e-09 37.3 0.2 7.6e-09 35.7 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EMD66379.1 - 2.2e-07 30.7 0.1 0.03 14.0 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD66379.1 - 8.7e-07 29.0 4.1 1e-05 25.5 0.2 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family FIST PF08495.5 EMD66379.1 - 0.011 14.9 0.1 3.2 6.8 0.0 2.9 3 0 0 3 3 3 0 FIST N domain Thiolase_N PF00108.18 EMD66379.1 - 0.066 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF2974 PF11187.3 EMD66379.1 - 0.35 10.1 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ketoacyl-synt PF00109.21 EMD66380.1 - 1.4e-69 234.4 0.0 4.5e-69 232.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD66380.1 - 6.4e-57 193.2 0.0 9.5e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMD66380.1 - 9.5e-57 192.4 0.0 1.7e-56 191.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMD66380.1 - 6.3e-55 185.6 4.0 6.6e-55 185.5 1.5 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMD66380.1 - 4.7e-42 143.7 2.6 1.5e-41 142.0 1.8 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD66380.1 - 6.3e-34 116.3 0.3 1.9e-33 114.8 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMD66380.1 - 4.4e-18 65.5 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMD66380.1 - 2.3e-11 43.3 0.1 5.9e-11 42.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMD66380.1 - 3.4e-11 43.1 0.0 1.1e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD66380.1 - 3.3e-09 36.5 0.0 9e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD66380.1 - 9.3e-08 32.4 0.0 3e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66380.1 - 1.1e-07 32.3 0.0 1.7e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EMD66380.1 - 1.8e-05 24.4 0.1 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EMD66380.1 - 0.00091 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMD66380.1 - 0.0034 17.3 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMD66380.1 - 0.0078 16.4 0.3 0.022 14.9 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Prenyltrans_2 PF13249.1 EMD66381.1 - 1.1e-30 106.3 5.7 1.8e-12 47.6 0.1 5.6 3 3 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMD66381.1 - 1e-28 99.5 3.8 6.8e-16 58.2 0.2 5.4 4 1 2 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 EMD66381.1 - 3.5e-23 80.8 6.8 6.2e-08 32.0 0.2 5.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EMD66381.1 - 1.5e-07 30.9 1.5 0.086 11.9 0.0 4.8 3 1 2 5 5 5 2 Pectic acid lyase Mago-bind PF09282.5 EMD66381.1 - 0.051 13.1 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Mago binding FAD_binding_3 PF01494.14 EMD66382.1 - 1.8e-19 70.0 0.3 6.6e-19 68.1 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD66382.1 - 7.2e-07 29.2 0.1 1.9e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD66382.1 - 2.7e-06 26.5 7.7 0.00035 19.5 1.3 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD66382.1 - 2.5e-05 23.3 2.2 4.1e-05 22.6 0.9 1.8 1 1 1 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EMD66382.1 - 3.7e-05 22.5 3.7 0.03 12.9 0.3 3.1 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EMD66382.1 - 8.1e-05 22.5 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD66382.1 - 0.00042 19.3 1.7 0.0055 15.6 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EMD66382.1 - 0.00088 18.4 1.5 0.0014 17.8 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD66382.1 - 0.0018 17.4 0.4 0.65 9.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EMD66382.1 - 0.0023 16.4 1.0 0.021 13.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EMD66382.1 - 0.0032 17.8 2.2 0.062 13.7 1.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD66382.1 - 0.0076 15.3 0.2 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EMD66382.1 - 0.043 12.6 0.4 0.053 12.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EMD66382.1 - 0.089 12.3 0.3 0.21 11.1 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EMD66383.1 - 8.8e-24 84.2 0.1 4.2e-23 81.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EMD66383.1 - 6.5e-09 35.3 0.3 0.0027 16.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMD66383.1 - 9.5e-05 22.7 0.4 0.0035 17.7 0.2 3.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD66383.1 - 0.00031 20.6 0.6 0.00086 19.2 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD66383.1 - 0.00046 19.2 0.5 0.0033 16.3 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMD66383.1 - 0.0018 17.2 3.4 0.1 11.4 2.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD66383.1 - 0.013 14.4 0.4 0.021 13.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EMD66383.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMN_red PF03358.10 EMD66384.1 - 4.9e-34 117.0 0.0 5.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EMD66384.1 - 0.00025 20.5 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold p450 PF00067.17 EMD66385.1 - 1.4e-37 129.3 0.0 2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3435 PF11917.3 EMD66386.1 - 1.9e-143 478.1 0.1 2.2e-143 477.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 EMD66387.1 - 1.7e-09 37.4 34.6 0.013 15.8 0.6 7.7 6 1 1 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD66387.1 - 1.3e-08 34.5 27.8 0.053 13.8 0.1 7.6 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMD66387.1 - 8.9e-05 22.5 23.5 0.0055 16.7 0.1 5.0 2 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMD66387.1 - 0.0016 18.4 34.6 0.054 13.6 0.6 7.0 8 1 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD66387.1 - 0.0021 18.1 26.8 2.8 8.2 0.5 7.3 6 1 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMD66387.1 - 4.8 7.2 33.3 5.1 7.1 0.4 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger OTT_1508_deam PF14441.1 EMD66388.1 - 4.2e-19 68.7 0.0 1.7e-18 66.8 0.0 2.0 1 1 1 2 2 2 1 OTT_1508-like deaminase BTB PF00651.26 EMD66389.1 - 3e-12 46.4 0.1 4.2e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain DDE_1 PF03184.14 EMD66390.1 - 5e-36 123.8 0.0 9e-28 96.8 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EMD66390.1 - 4.3e-08 33.0 0.0 5.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease NACHT PF05729.7 EMD66392.1 - 3.4e-13 49.6 0.2 1.5e-12 47.4 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EMD66392.1 - 5.1e-08 33.1 0.1 3.1e-06 27.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD66392.1 - 1.9e-07 31.3 0.0 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 EMD66392.1 - 9.8e-06 25.8 1.6 0.012 15.8 0.0 3.5 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD66392.1 - 5.4e-05 23.5 3.0 0.078 13.5 0.1 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD66392.1 - 0.001 19.2 2.0 0.11 12.7 0.1 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Arch_ATPase PF01637.13 EMD66392.1 - 0.004 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EMD66392.1 - 0.022 13.7 0.2 0.099 11.6 0.1 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA PF00004.24 EMD66392.1 - 0.098 12.8 0.2 0.6 10.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_3 PF13606.1 EMD66392.1 - 1.2 9.5 5.0 55 4.4 0.0 4.5 6 0 0 6 6 6 0 Ankyrin repeat SWIM PF04434.12 EMD66395.1 - 7.4e-08 31.7 0.2 1.3e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF2239 PF09998.4 EMD66396.1 - 0.015 14.9 0.2 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) LXG PF04740.7 EMD66396.1 - 0.035 13.8 0.3 0.045 13.5 0.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily ApoO PF09769.4 EMD66396.1 - 0.094 12.4 1.1 0.15 11.7 0.7 1.3 1 0 0 1 1 1 0 Apolipoprotein O CP12 PF02672.10 EMD66396.1 - 0.43 11.0 2.1 5 7.6 0.2 2.6 1 1 1 2 2 2 0 CP12 domain APH PF01636.18 EMD66397.1 - 1.8e-12 47.5 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD66397.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EMD66397.1 - 0.0021 17.2 0.0 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 EMD66397.1 - 0.06 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 EMD66397.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C2H2_4 PF13894.1 EMD66398.1 - 1.4e-06 28.2 22.3 0.12 12.7 0.8 5.9 5 1 1 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMD66398.1 - 3.7e-06 26.6 22.6 0.0077 16.1 0.1 5.2 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD66398.1 - 5.7e-05 23.2 37.6 0.0041 17.3 0.2 5.9 7 0 0 7 7 6 3 Zinc finger, C2H2 type zf-met PF12874.2 EMD66398.1 - 0.0053 16.9 16.3 8 6.8 0.0 6.1 6 0 0 6 6 6 1 Zinc-finger of C2H2 type Proho_convert PF12177.3 EMD66398.1 - 0.065 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Prohormone convertase enzyme zf-C2H2_jaz PF12171.3 EMD66398.1 - 0.086 13.0 22.1 1 9.5 0.2 5.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD66398.1 - 0.13 12.3 18.2 0.89 9.7 0.9 4.8 1 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EMD66398.1 - 0.15 12.0 0.2 0.15 12.0 0.1 4.2 4 1 0 4 4 4 0 Zinc ribbon domain zf-A20 PF01754.11 EMD66398.1 - 0.29 10.7 0.1 0.29 10.7 0.0 3.2 5 0 0 5 5 5 0 A20-like zinc finger zf-C2HC_2 PF13913.1 EMD66398.1 - 0.71 9.6 9.1 6.3 6.5 0.2 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF3795 PF12675.2 EMD66398.1 - 2.2 8.5 14.4 7.5 6.8 0.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3795) DnaJ_CXXCXGXG PF00684.14 EMD66398.1 - 2.7 8.1 10.4 3.3 7.8 1.3 3.7 2 1 3 5 5 5 0 DnaJ central domain PPV_E2_N PF00508.12 EMD66400.1 - 0.043 12.9 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal TPR_10 PF13374.1 EMD66402.1 - 1.1e-41 139.5 4.5 1.5e-12 46.9 0.0 5.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66402.1 - 1.5e-41 140.2 17.5 4.4e-15 55.3 0.1 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD66402.1 - 2.3e-11 42.6 1.4 0.031 14.0 0.0 4.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD66402.1 - 1.1e-08 34.3 0.1 0.14 11.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD66402.1 - 7e-07 28.9 0.3 1.3 9.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD66402.1 - 2.5e-06 27.5 4.5 0.04 14.0 0.1 3.2 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMD66402.1 - 0.00019 20.9 2.1 0.61 9.7 0.3 3.3 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EMD66402.1 - 0.00026 21.5 0.3 5.8 7.7 0.0 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD66402.1 - 0.0012 18.5 1.5 24 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EMD66402.1 - 0.015 15.2 1.0 1.6 8.6 0.2 2.7 1 1 2 3 3 3 0 Rabaptin-like protein TPR_19 PF14559.1 EMD66402.1 - 0.027 14.8 0.0 3.6 7.9 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1996 PF09362.5 EMD66404.1 - 2e-37 129.1 0.0 3.4e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF2408 PF10303.4 EMD66404.1 - 1.1 9.3 5.0 0.4 10.7 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NAD_binding_6 PF08030.7 EMD66405.1 - 2.4e-09 37.2 0.0 1.6e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD66405.1 - 3.4e-07 30.1 0.0 6.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain AIG1 PF04548.11 EMD66406.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Flp_N PF03930.9 EMD66408.1 - 0.03 14.0 0.3 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus Filament PF00038.16 EMD66408.1 - 0.04 13.3 14.1 0.045 13.2 3.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein MbeD_MobD PF04899.7 EMD66408.1 - 0.077 12.9 0.5 0.077 12.9 0.4 2.3 2 0 0 2 2 2 0 MbeD/MobD like Tropomyosin PF00261.15 EMD66408.1 - 0.12 11.4 13.1 0.03 13.4 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin Mis14 PF08641.7 EMD66408.1 - 0.18 11.8 4.8 4.8 7.2 0.4 2.5 2 2 0 2 2 2 0 Kinetochore protein Mis14 like PMC2NT PF08066.7 EMD66408.1 - 0.22 11.8 5.9 3.6 7.9 0.1 3.4 1 1 2 3 3 3 0 PMC2NT (NUC016) domain LMBR1 PF04791.11 EMD66408.1 - 0.25 9.8 3.8 0.13 10.7 1.1 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein HalX PF08663.5 EMD66408.1 - 0.55 10.2 3.8 4.5 7.3 0.1 2.8 2 1 0 3 3 3 0 HalX domain TBPIP PF07106.8 EMD66408.1 - 0.55 9.7 8.7 0.19 11.2 0.5 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EMD66408.1 - 0.69 9.6 7.4 2.9 7.6 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II DivIVA PF05103.8 EMD66408.1 - 0.74 9.8 13.9 0.082 12.9 1.0 2.8 1 1 0 2 2 2 0 DivIVA protein DUF883 PF05957.8 EMD66408.1 - 0.78 10.1 4.3 1.9 8.9 0.3 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UPF0449 PF15136.1 EMD66408.1 - 0.79 9.9 7.8 0.47 10.6 0.4 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 ERM PF00769.14 EMD66408.1 - 1.1 8.7 14.6 3.1 7.2 1.1 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 EMD66408.1 - 1.2 8.6 21.1 2.3 7.7 7.9 2.1 1 1 1 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 EMD66408.1 - 2.5 8.5 8.0 0.8 10.1 0.7 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EMD66408.1 - 5.5 6.8 10.7 0.29 10.9 1.1 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Zein-binding PF04576.10 EMD66408.1 - 5.6 7.1 9.4 2.1 8.5 2.2 2.8 2 2 0 2 2 2 0 Zein-binding I_LWEQ PF01608.12 EMD66408.1 - 9.5 6.1 10.8 9.9 6.0 2.0 2.4 1 1 0 2 2 2 0 I/LWEQ domain YgaB PF14182.1 EMD66409.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 YgaB-like protein SNARE PF05739.14 EMD66409.1 - 0.024 14.3 0.3 0.99 9.1 0.0 2.4 1 1 1 2 2 2 0 SNARE domain Spc24 PF08286.6 EMD66409.1 - 0.091 12.4 0.4 0.18 11.5 0.3 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HR1 PF02185.11 EMD66409.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Hr1 repeat Patatin PF01734.17 EMD66410.1 - 0.051 13.5 0.1 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Patatin-like phospholipase DUF3723 PF12520.3 EMD66411.1 - 3.3e-48 164.4 0.9 8.2e-48 163.1 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Death PF00531.17 EMD66411.1 - 0.029 14.1 0.3 4.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Death domain Amb_V_allergen PF03913.8 EMD66411.1 - 0.031 13.9 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Amb V Allergen bZIP_1 PF00170.16 EMD66412.1 - 5.1 7.1 7.9 14 5.7 5.5 1.8 1 1 0 1 1 1 0 bZIP transcription factor BTB PF00651.26 EMD66413.1 - 1e-06 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF221 PF02714.10 EMD66414.1 - 3.7e-65 219.9 17.5 1.3e-60 204.9 4.9 3.1 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD66414.1 - 6.5e-18 64.7 2.8 7.1e-17 61.4 1.9 2.6 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMD66414.1 - 0.012 16.1 1.3 0.022 15.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EMD66414.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphate metabolism protein Asp PF00026.18 EMD66418.1 - 1.6e-05 24.3 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Mo-co_dimer PF03404.11 EMD66420.1 - 0.04 13.5 0.0 0.072 12.7 0.0 1.5 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain PX PF00787.19 EMD66420.1 - 0.046 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 PX domain DUF3508 PF12018.3 EMD66421.1 - 0.05 12.5 1.1 0.061 12.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Rho_Binding PF08912.6 EMD66423.1 - 0.01 16.1 8.3 0.01 16.1 5.7 5.2 5 1 1 6 6 6 0 Rho Binding zf-C2HC_2 PF13913.1 EMD66426.1 - 0.025 14.2 2.0 0.1 12.3 1.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EMD66426.1 - 0.048 14.0 2.8 0.048 14.0 2.0 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD66426.1 - 0.18 12.2 3.1 0.43 11.0 2.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger CAP PF00188.21 EMD66427.1 - 0.035 14.5 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich secretory protein family APH PF01636.18 EMD66430.1 - 1.1e-13 51.4 0.0 3.3e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD66430.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_U57 PF05582.7 EMD66431.1 - 0.099 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 OTT_1508_deam PF14441.1 EMD66432.1 - 2.5e-09 37.0 0.0 5.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Myb_DNA-bind_6 PF13921.1 EMD66433.1 - 0.00011 22.1 0.2 0.00048 20.1 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cu_bind_like PF02298.12 EMD66434.1 - 0.24 11.2 1.4 0.3 10.9 1.0 1.2 1 0 0 1 1 1 0 Plastocyanin-like domain Pet191_N PF10203.4 EMD66434.1 - 0.81 9.7 4.3 1.4 9.0 2.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3450 PF11932.3 EMD66436.1 - 0.15 11.2 7.1 0.19 10.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2 PF06886.6 EMD66436.1 - 5.8 7.0 10.0 7 6.7 2.7 2.1 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) PAXNEB PF05625.6 EMD66437.1 - 0.0047 15.8 0.7 0.0049 15.7 0.5 1.0 1 0 0 1 1 1 1 PAXNEB protein BOP1NT PF08145.7 EMD66437.1 - 0.021 14.5 1.1 0.024 14.3 0.7 1.0 1 0 0 1 1 1 0 BOP1NT (NUC169) domain RVT_1 PF00078.22 EMD66439.1 - 0.0031 16.9 0.2 0.0031 16.9 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4319 PF14203.1 EMD66439.1 - 0.035 13.6 0.1 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) EABR PF12180.3 EMD66439.1 - 0.32 10.3 2.6 4.3 6.7 1.8 2.1 1 1 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Ras PF00071.17 EMD66440.1 - 4.5e-52 175.6 0.1 1.4e-51 174.1 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMD66440.1 - 4.8e-18 65.7 0.0 5.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMD66440.1 - 0.00018 20.7 0.0 0.00063 19.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD66440.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD66440.1 - 0.015 14.7 0.1 4.3 6.7 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMD66440.1 - 0.026 13.8 0.1 0.29 10.3 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 EMD66440.1 - 0.076 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EMD66440.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.7 EMD66440.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region K-cyclin_vir_C PF09080.5 EMD66442.1 - 0.16 12.2 1.3 0.34 11.1 0.9 1.6 1 0 0 1 1 1 0 K cyclin, C terminal AMP-binding PF00501.23 EMD66443.1 - 1.6e-81 273.8 0.0 1.9e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD66443.1 - 7.4e-13 49.2 0.0 1.7e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HAD_2 PF13419.1 EMD66444.1 - 1e-23 84.4 0.9 1.8e-23 83.6 0.2 1.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD66444.1 - 2e-09 38.1 0.0 3.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD66444.1 - 2.7e-07 30.1 0.1 8e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like NFRKB_winged PF14465.1 EMD66444.1 - 2.3 8.0 5.6 69 3.3 3.2 2.9 1 1 1 2 2 2 0 NFRKB Winged Helix-like Histone PF00125.19 EMD66445.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EMD66445.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EMD66445.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMD66445.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMD66445.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMD66445.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EMD66446.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMD66446.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMD66446.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMD66446.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated AhpC-TSA_2 PF13911.1 EMD66447.1 - 2.2e-07 30.8 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 EMD66447.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMD66447.1 - 1.7e-05 24.5 0.0 2.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Exo5 PF09810.4 EMD66448.1 - 9.1e-117 389.8 0.0 1.2e-116 389.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Glyco_hydro_43 PF04616.9 EMD66449.1 - 9.1e-35 120.1 13.7 1.1e-34 119.8 9.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RED_N PF07808.8 EMD66450.1 - 1.5e-06 27.6 6.4 4.4e-06 26.0 4.5 1.8 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.7 EMD66450.1 - 0.036 13.8 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Gas vesicle protein G PALP PF00291.20 EMD66451.1 - 9e-50 169.6 0.6 1.1e-49 169.3 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_photolyase PF00875.13 EMD66451.1 - 0.061 13.0 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 DNA photolyase EI24 PF07264.6 EMD66452.1 - 0.00025 20.5 6.0 0.00025 20.5 4.1 2.3 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Asp PF00026.18 EMD66453.1 - 2.9e-108 361.8 0.0 3.4e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMD66453.1 - 1.7e-10 41.0 0.0 4e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMD66453.1 - 5e-06 26.1 0.0 3.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EMD66453.1 - 9.4e-06 26.0 0.0 0.027 14.9 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Glyco_transf_28 PF03033.15 EMD66454.1 - 1.1e-23 83.5 0.0 2.1e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EMD66454.1 - 5.3e-23 80.3 2.5 1.5e-13 50.0 0.1 3.3 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 EMD66454.1 - 1.4e-15 57.3 0.2 1e-14 54.5 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMD66454.1 - 2.5e-05 24.5 0.5 0.00013 22.1 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EMD66454.1 - 4.4e-05 22.2 0.0 8.6e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 EMD66454.1 - 0.00016 21.5 0.1 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 PH domain NIF PF03031.13 EMD66455.1 - 4.7e-25 88.0 0.9 7.8e-25 87.3 0.1 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EMD66455.1 - 1.2e-10 41.4 0.0 6.4e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD66455.1 - 1.8e-10 40.5 0.0 4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Cut8_N PF14482.1 EMD66455.1 - 3 7.9 12.4 1.9 8.5 6.8 2.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain F-box-like PF12937.2 EMD66456.1 - 0.021 14.5 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 F-box-like Zn_clus PF00172.13 EMD66457.1 - 2.2e-08 33.8 9.0 4.1e-08 32.9 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD66457.1 - 1.2e-05 24.3 0.0 3.7e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SPC25 PF06703.6 EMD66457.1 - 0.033 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ribosomal_L11_N PF03946.9 EMD66458.1 - 3.2e-27 93.7 0.4 6.6e-27 92.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMD66458.1 - 1.6e-16 60.1 1.4 1.6e-16 60.1 0.9 2.1 2 1 0 2 2 2 1 Ribosomal protein L11, RNA binding domain SNF2_N PF00176.18 EMD66459.1 - 4.9e-66 222.5 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EMD66459.1 - 1.9e-60 204.0 0.9 1.9e-59 200.7 0.5 2.3 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EMD66459.1 - 1.8e-13 50.0 0.0 8.2e-13 48.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMD66459.1 - 0.002 17.0 0.0 0.0074 15.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMD66459.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SyrA PF11089.3 EMD66460.1 - 0.081 12.7 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Exopolysaccharide production repressor OB_NTP_bind PF07717.11 EMD66461.1 - 1.3e-25 89.4 0.0 3.4e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMD66461.1 - 2e-23 82.3 1.1 3.3e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMD66461.1 - 4.7e-13 48.8 0.0 2.9e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mannitol_dh PF01232.18 EMD66461.1 - 0.021 14.7 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain zf-DNL PF05180.7 EMD66462.1 - 8.8e-30 102.2 0.8 1.2e-29 101.8 0.6 1.2 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.14 EMD66462.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 EMD66462.1 - 0.077 12.6 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 EMD66462.1 - 0.079 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Cullin PF00888.17 EMD66463.1 - 3.2e-138 461.8 6.5 4.4e-138 461.4 4.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMD66463.1 - 5.5e-27 93.3 3.9 1.3e-26 92.2 0.5 3.1 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_Gp23 PF10669.4 EMD66463.1 - 0.0099 15.9 2.3 0.0099 15.9 1.6 2.0 2 0 0 2 2 2 1 Protein gp23 (Bacteriophage A118) Rrf2 PF02082.15 EMD66463.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator Sas10_Utp3 PF04000.10 EMD66464.1 - 4.9e-17 61.9 2.5 9e-17 61.0 1.7 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Zn_clus PF00172.13 EMD66465.1 - 6.3e-09 35.5 8.4 6.3e-09 35.5 5.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD66465.1 - 1.4e-06 27.3 0.0 2.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.9 EMD66470.1 - 7.3e-23 79.8 1.2 1.5e-16 59.6 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Evr1_Alr PF04777.8 EMD66471.1 - 5.9e-29 99.8 3.7 2.5e-28 97.8 2.1 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Pkinase PF00069.20 EMD66472.1 - 1.5e-73 247.1 0.0 1.9e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66472.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD66472.1 - 0.0004 19.4 0.0 0.00078 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD66472.1 - 0.002 17.2 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD66472.1 - 0.0082 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMD66472.1 - 0.027 13.3 0.1 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 EMD66475.1 - 1.8e-47 161.0 0.0 2.6e-46 157.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD66475.1 - 4.7e-25 87.2 0.0 1.3e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EMD66475.1 - 0.00049 18.6 0.0 0.0034 15.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EMD66475.1 - 0.02 13.9 0.0 0.02 13.9 0.0 2.9 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF4407 PF14362.1 EMD66475.1 - 2.1 7.2 18.8 3.2 6.6 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIIC_delta PF12657.2 EMD66476.1 - 9.7e-39 132.8 0.5 3e-37 127.9 0.2 2.5 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EMD66476.1 - 6e-25 87.0 1.4 4.3e-22 77.8 0.2 2.5 2 0 0 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex Head_binding PF09008.5 EMD66476.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Head binding CENP-B_dimeris PF09026.5 EMD66476.1 - 1.3 9.2 10.1 3.8 7.8 7.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EMD66476.1 - 1.4 8.4 11.3 16 4.9 8.7 2.0 2 0 0 2 2 2 0 Nucleoplasmin Ctr PF04145.10 EMD66477.1 - 1.1e-40 139.0 1.4 1.3e-40 138.8 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EMD66477.1 - 0.029 13.9 0.7 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4407 PF14362.1 EMD66477.1 - 0.12 11.2 1.6 0.18 10.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TraL PF07178.6 EMD66477.1 - 2.2 8.3 5.3 6 6.9 0.3 2.1 2 0 0 2 2 2 0 TraL protein YfhO PF09586.5 EMD66477.1 - 4 5.3 9.8 1.3 7.0 4.6 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4066 PF13278.1 EMD66478.1 - 5.1e-26 90.9 0.0 6.8e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD66478.1 - 4e-08 32.8 0.0 5.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EMD66478.1 - 0.0042 16.5 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DIT1_PvcA PF05141.7 EMD66479.1 - 1.4e-81 273.8 0.0 1.9e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 EMD66480.1 - 3.1e-61 207.3 0.0 3.8e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMD66481.1 - 1.8e-38 132.1 37.3 1.8e-38 132.1 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DSBA PF01323.15 EMD66482.1 - 3.4e-37 127.9 0.0 3.8e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EMD66482.1 - 2.2e-05 24.5 0.5 8.2e-05 22.6 0.0 1.9 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 EMD66482.1 - 0.003 17.1 0.0 0.0076 15.8 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EMD66482.1 - 0.14 11.9 0.2 3 7.7 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin domain Cellulase PF00150.13 EMD66483.1 - 1.1e-06 28.0 5.6 8.3e-06 25.2 3.9 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMD66483.1 - 0.0021 18.4 0.0 0.006 16.9 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like Ribosomal_S18 PF01084.15 EMD66484.1 - 7.6e-15 54.5 0.4 2.1e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S18 PPR_3 PF13812.1 EMD66485.1 - 5.6e-08 32.4 5.6 1 9.7 0.0 7.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EMD66485.1 - 1.5e-06 28.0 2.5 0.2 11.6 0.0 6.3 6 1 0 6 6 6 1 PPR repeat family PPR PF01535.15 EMD66485.1 - 4.5e-05 23.1 4.4 2.7 8.1 0.0 6.1 7 0 0 7 7 7 2 PPR repeat ATP13 PF12921.2 EMD66485.1 - 0.067 12.5 0.0 5.8 6.2 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_12 PF13424.1 EMD66485.1 - 0.089 12.7 4.0 28 4.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_5 PF13854.1 EMD66486.1 - 2.3e-14 52.9 5.4 6.3e-08 32.4 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EMD66486.1 - 1.3e-11 44.3 10.4 0.0027 17.8 0.0 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMD66486.1 - 1.4e-08 34.5 8.3 0.0099 16.0 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EMD66486.1 - 2.9e-07 30.1 13.7 0.084 12.6 0.8 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EMD66486.1 - 0.00018 20.9 5.6 0.76 9.3 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EMD66486.1 - 0.16 11.8 8.8 0.18 11.6 0.2 4.4 6 0 0 6 6 6 0 Kelch motif Adeno_E3_CR2 PF02439.10 EMD66486.1 - 9.1 5.9 5.4 18 5.0 3.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myb_DNA-binding PF00249.26 EMD66487.1 - 8e-20 70.6 5.4 5e-13 48.8 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD66487.1 - 4.6e-11 42.6 3.1 4.6e-11 42.6 2.2 4.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Mito_carr PF00153.22 EMD66489.1 - 1e-61 204.6 8.7 7.4e-22 76.8 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.21 EMD66490.1 - 1.9e-21 75.9 0.1 3.8e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD66490.1 - 8.6e-13 49.2 0.0 1.7e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD66490.1 - 8.5e-09 35.1 0.0 5.7e-07 29.2 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain F_bP_aldolase PF01116.15 EMD66490.1 - 0.038 13.0 0.4 0.079 12.0 0.1 1.6 1 1 1 2 2 2 0 Fructose-bisphosphate aldolase class-II Zeta_toxin PF06414.7 EMD66490.1 - 0.052 12.6 0.1 0.14 11.2 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin DapB_N PF01113.15 EMD66490.1 - 0.094 12.6 0.2 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rep_fac-A_C PF08646.5 EMD66491.1 - 9.9e-54 181.0 1.9 1.5e-49 167.4 0.8 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EMD66491.1 - 4.4e-21 74.5 0.3 4.4e-21 74.5 0.2 2.0 3 0 0 3 3 3 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EMD66491.1 - 3.6e-13 49.1 0.1 6.9e-08 32.2 0.0 3.7 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF3888 PF13027.1 EMD66491.1 - 0.51 10.2 2.9 2.7 7.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3888) DLH PF01738.13 EMD66492.1 - 1.3e-17 63.8 0.2 1.8e-15 56.8 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMD66492.1 - 1.3e-07 31.4 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD66492.1 - 4e-06 26.8 0.0 0.00038 20.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMD66492.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold SnoaL_2 PF12680.2 EMD66493.1 - 3.8e-06 27.2 0.1 6.4e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EMD66493.1 - 5.5e-06 25.9 0.1 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 EMD66493.1 - 0.11 11.7 0.0 1.1 8.5 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Filamin PF00630.14 EMD66495.1 - 0.087 13.4 0.0 0.25 11.9 0.0 1.9 1 1 0 1 1 1 0 Filamin/ABP280 repeat DUF3324 PF11797.3 EMD66495.1 - 0.13 12.0 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) AhpC-TSA PF00578.16 EMD66496.1 - 2.9e-33 114.2 0.0 3.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMD66496.1 - 5.1e-16 58.5 0.0 7.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMD66496.1 - 3.3e-15 55.4 0.1 6.4e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PMSI1 PF15322.1 EMD66496.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative PCI PF01399.22 EMD66497.1 - 0.0021 18.3 0.1 0.051 13.8 0.0 2.9 3 0 0 3 3 3 1 PCI domain Apc3 PF12895.2 EMD66497.1 - 0.0071 16.4 2.5 0.029 14.4 1.7 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Pyr_redox_3 PF13738.1 EMD66498.1 - 3.1e-19 69.8 0.0 1.2e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD66498.1 - 3.2e-14 52.0 0.0 4.3e-13 48.3 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMD66498.1 - 3e-11 43.5 0.0 2.6e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD66498.1 - 2.1e-10 40.0 0.0 2.1e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD66498.1 - 8.8e-07 28.8 0.8 3.6e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMD66498.1 - 2e-05 24.7 0.1 0.53 10.3 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMD66498.1 - 3.6e-05 24.0 0.6 0.32 11.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD66498.1 - 0.00011 21.9 0.3 0.082 12.6 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EMD66498.1 - 0.0012 17.7 1.3 0.0045 15.9 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD66498.1 - 0.081 11.7 0.2 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EMD66498.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMD66498.1 - 0.12 11.4 0.0 5.2 6.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EMD66498.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMD66498.1 - 0.24 10.4 0.9 0.98 8.4 0.0 2.2 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 EMD66498.1 - 7.9 5.2 5.3 0.95 8.2 0.2 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Rhodanese PF00581.15 EMD66500.1 - 1.5e-14 54.2 0.0 3.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF1940 PF09155.5 EMD66500.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Sld5 PF05916.6 EMD66501.1 - 3.9e-07 30.3 0.1 7.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein E1-E2_ATPase PF00122.15 EMD66502.1 - 9.7e-77 257.0 0.0 1.7e-76 256.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD66502.1 - 1.6e-42 145.0 0.2 3.5e-42 143.9 0.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD66502.1 - 2.1e-29 103.5 0.1 1.7e-28 100.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD66502.1 - 5.7e-19 67.3 0.2 1.2e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EMD66502.1 - 1.5e-14 53.6 0.0 2.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD66502.1 - 7.3e-14 52.3 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD66502.1 - 0.00017 21.2 2.2 0.0003 20.4 0.9 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1996 PF09362.5 EMD66503.1 - 2.5e-78 262.9 0.1 3.2e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Rad21_Rec8_N PF04825.8 EMD66504.1 - 9.6e-34 115.6 0.0 1.6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMD66504.1 - 1.5e-07 30.4 0.0 3.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EMD66504.1 - 0.07 12.6 1.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 ScpA/B protein Fungal_trans PF04082.13 EMD66505.1 - 8.7e-25 87.0 0.4 1.3e-24 86.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66505.1 - 2.1e-10 40.3 8.6 3.4e-10 39.6 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.8 EMD66506.1 - 2.9e-100 335.6 0.9 6.3e-92 308.1 0.9 2.0 2 0 0 2 2 2 2 PrpF protein Sua5_yciO_yrdC PF01300.13 EMD66507.1 - 5.3e-53 178.9 0.0 8.7e-53 178.2 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EMD66507.1 - 8.8e-28 96.8 0.0 2.3e-27 95.5 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding CBM_19 PF03427.8 EMD66508.1 - 0.067 12.9 0.9 0.098 12.4 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Glyco_hydro_cc PF11790.3 EMD66509.1 - 8.5e-58 195.5 0.5 1.1e-57 195.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 EMD66509.1 - 0.0042 15.9 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 SSXT PF05030.7 EMD66510.1 - 0.00013 21.4 0.0 0.064 12.8 0.0 2.5 2 0 0 2 2 2 2 SSXT protein (N-terminal region) FtsJ PF01728.14 EMD66511.1 - 7.4e-58 195.5 0.0 1e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EMD66511.1 - 0.0059 16.3 0.0 0.026 14.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66511.1 - 0.055 14.0 0.0 0.11 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.22 EMD66512.1 - 4.8e-73 240.9 4.6 1.8e-24 85.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GAD-like PF08887.6 EMD66512.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 GAD-like domain 2Fe-2S_thioredx PF01257.14 EMD66513.1 - 2.3e-62 208.9 0.6 2.8e-62 208.6 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3824 PF12868.2 EMD66516.1 - 6.2e-31 108.1 37.0 6.2e-31 108.1 25.7 10.8 7 4 3 11 11 11 2 Domain of unknwon function (DUF3824) DUF533 PF04391.7 EMD66516.1 - 0.0085 15.4 18.8 0.17 11.2 1.9 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF533) ABA_WDS PF02496.11 EMD66516.1 - 0.027 14.6 22.2 0.4 10.8 0.5 4.9 4 0 0 4 4 4 0 ABA/WDS induced protein HIG_1_N PF04588.8 EMD66516.1 - 0.078 12.7 0.3 2.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DUF3040 PF11239.3 EMD66516.1 - 0.11 12.5 1.6 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) CorA PF01544.13 EMD66517.1 - 6.3e-45 153.4 1.8 3e-22 79.0 1.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 EMD66518.1 - 1.9e-29 102.5 33.7 1.9e-29 102.5 23.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIA PF03153.8 EMD66520.1 - 4.6 7.0 6.7 5.1 6.8 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acyltransferase PF01553.16 EMD66521.1 - 3.8e-27 94.3 0.0 6.2e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Hep_59 PF07052.6 EMD66522.1 - 3.3e-08 33.8 0.0 3.3e-08 33.8 0.0 3.5 4 1 0 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 NifU_N PF01592.11 EMD66523.1 - 4.4e-52 175.3 0.0 5.7e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DNA_pol_phi PF04931.8 EMD66524.1 - 2.7e-47 161.0 32.2 2.7e-36 124.7 16.3 2.4 2 1 0 2 2 2 2 DNA polymerase phi UCH PF00443.24 EMD66524.1 - 1.3e-43 149.0 1.2 4.1e-42 144.1 0.0 3.3 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Med4 PF10018.4 EMD66524.1 - 2e-36 125.1 2.1 2e-36 125.1 1.4 2.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 zf-UBP PF02148.14 EMD66524.1 - 1.7e-25 88.9 7.5 7.7e-20 70.7 0.7 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EMD66524.1 - 2.3e-20 71.8 0.1 6e-09 35.4 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EMD66524.1 - 4.5e-20 72.2 0.3 5.6e-19 68.6 0.0 3.0 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.27 EMD66525.1 - 7.3e-24 81.2 12.4 6.1e-08 31.4 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EMD66525.1 - 1.4e-22 77.4 3.5 4.7e-06 26.0 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EMD66525.1 - 3.2e-21 75.2 2.5 8.3e-13 48.2 0.1 3.3 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMD66525.1 - 4.9e-18 63.5 11.5 2.3e-05 23.5 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EMD66525.1 - 5.5e-14 51.5 11.5 1.3e-05 24.6 0.8 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EMD66525.1 - 3.3e-08 33.2 6.2 0.002 17.8 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMD66525.1 - 0.00068 19.6 1.7 0.66 10.0 0.1 3.2 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EMD66525.1 - 0.0027 17.6 0.5 0.041 13.7 0.0 2.9 3 1 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EMD66525.1 - 0.014 15.0 2.1 2 8.1 0.0 3.9 4 0 0 4 4 4 0 EF hand Toprim PF01751.17 EMD66525.1 - 0.039 13.9 0.0 3.1 7.8 0.0 2.3 1 1 0 1 1 1 0 Toprim domain DUF1679 PF07914.6 EMD66525.1 - 0.048 12.2 0.5 2.2 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 EMD66525.1 - 0.049 13.6 0.2 4.1 7.4 0.0 3.0 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 EMD66525.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 EMP70 PF02990.11 EMD66526.1 - 1.6e-197 657.0 0.9 2e-197 656.7 0.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 EMD66526.1 - 0.61 9.3 4.8 0.99 8.6 1.5 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2448 PF10476.4 EMD66527.1 - 0.15 11.5 5.9 0.35 10.3 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) MBOAT PF03062.14 EMD66528.1 - 1.8e-34 119.3 28.6 3.7e-34 118.3 9.3 3.1 3 0 0 3 3 3 3 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMD66528.1 - 0.0023 17.9 5.0 0.0023 17.9 3.5 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 3HCDH_N PF02737.13 EMD66529.1 - 2.6e-35 121.6 0.0 4e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMD66529.1 - 7e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EMD66529.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EMD66529.1 - 0.033 14.5 0.5 0.089 13.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EMD66530.1 - 1.5e-82 277.1 0.0 1.9e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD66530.1 - 2.8e-12 47.4 0.7 1.4e-11 45.1 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.7 EMD66530.1 - 0.032 13.8 0.0 0.23 11.1 0.0 2.3 3 0 0 3 3 3 0 Rho termination factor, RNA-binding domain Metallophos PF00149.23 EMD66531.1 - 1.4e-09 37.6 1.1 2.4e-09 36.8 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2721 PF11026.3 EMD66532.1 - 0.024 14.2 0.4 0.05 13.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) WD40 PF00400.27 EMD66533.1 - 1.6e-30 103.8 2.9 6.1e-09 35.4 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMD66533.1 - 0.18 11.3 0.0 5.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.16 EMD66534.1 - 2.5e-15 56.1 9.7 4.1e-15 55.4 6.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD66534.1 - 1.6e-07 31.0 8.7 3.7e-07 29.8 6.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD66534.1 - 0.0012 19.1 4.6 0.0012 19.1 3.2 2.0 3 0 0 3 3 3 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 EMD66534.1 - 0.0085 15.2 0.2 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M PAT1 PF09770.4 EMD66534.1 - 1.8 6.7 18.4 2.3 6.3 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_3 PF13358.1 EMD66536.1 - 1.5e-07 31.2 0.9 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.1 EMD66536.1 - 0.00089 18.8 0.1 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Fungal_trans PF04082.13 EMD66537.1 - 3e-17 62.3 0.2 5.9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF318 PF03773.8 EMD66539.1 - 0.0012 17.9 0.4 0.0019 17.2 0.3 1.3 1 0 0 1 1 1 1 Predicted permease PGM_PMM_I PF02878.11 EMD66541.1 - 4.9e-41 139.4 0.0 9.2e-41 138.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMD66541.1 - 1.4e-22 79.9 0.0 3.8e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMD66541.1 - 4.1e-12 46.1 0.0 8.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EMD66541.1 - 1.1e-08 34.9 0.0 3.3e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Homeobox PF00046.24 EMD66541.1 - 0.029 13.9 0.0 0.095 12.3 0.0 1.8 1 0 0 1 1 1 0 Homeobox domain FA_desaturase PF00487.19 EMD66542.1 - 4.4e-34 118.0 29.2 7.1e-34 117.4 20.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMD66542.1 - 4.3e-13 48.8 0.2 4.1e-12 45.7 0.0 2.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Herpes_ICP4_C PF03585.9 EMD66543.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region XFP_N PF09364.5 EMD66544.1 - 1.2e-177 590.2 0.0 1.6e-177 589.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EMD66544.1 - 1.7e-85 285.5 0.0 2.7e-85 284.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EMD66544.1 - 4.4e-83 277.2 0.1 1.1e-82 275.9 0.0 1.7 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Kinesin PF00225.18 EMD66545.1 - 1.5e-83 280.2 0.2 2.2e-83 279.7 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_5 PF14520.1 EMD66545.1 - 0.00073 19.6 1.7 0.0014 18.7 0.1 2.3 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EMD66545.1 - 0.00086 18.8 0.0 0.25 11.1 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix motif zf-UBR PF02207.15 EMD66547.1 - 1.8e-16 59.5 4.7 1.8e-16 59.5 3.3 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EMD66548.1 - 3.3e-139 463.3 0.0 4.6e-139 462.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EMD66548.1 - 7.5e-35 120.2 33.2 7.5e-35 120.2 23.0 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EMD66548.1 - 3e-20 72.8 0.1 6.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMD66548.1 - 1.8e-08 33.8 0.1 1.9e-06 27.1 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMD66548.1 - 3e-06 27.0 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMD66548.1 - 0.0016 18.0 0.0 0.0058 16.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMD66548.1 - 0.0017 17.8 0.1 0.011 15.2 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain FAM92 PF06730.6 EMD66548.1 - 0.014 14.7 1.9 0.03 13.6 1.3 1.4 1 0 0 1 1 1 0 FAM92 protein Ribosomal_L7Ae PF01248.21 EMD66549.1 - 5.6e-26 89.8 0.0 6.3e-26 89.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EMD66550.1 - 5.6e-33 113.5 0.1 8.1e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e APG9 PF04109.11 EMD66551.1 - 2.3e-145 484.1 1.5 3.1e-145 483.7 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.6 EMD66552.1 - 8e-230 764.1 11.1 9.1e-230 763.9 7.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EMD66552.1 - 0.0022 17.8 1.6 0.024 14.4 0.2 3.1 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EMD66552.1 - 0.18 11.5 6.1 4.5 7.0 0.1 3.6 2 2 1 3 3 3 0 Laminin Domain II BolA PF01722.13 EMD66553.1 - 2.2e-21 75.6 0.0 3.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EMD66554.1 - 6.2e-59 199.4 0.0 8.2e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Band_7 PF01145.20 EMD66556.1 - 2.5e-14 53.5 0.1 2.5e-14 53.5 0.0 2.9 1 1 0 2 2 2 1 SPFH domain / Band 7 family TraV PF09676.5 EMD66560.1 - 1.5 9.5 6.0 28 5.4 0.0 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) V_ATPase_I PF01496.14 EMD66563.1 - 3.3 5.4 17.6 6.1 4.5 12.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_3 PF13358.1 EMD66564.1 - 2.5e-07 30.5 0.9 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Sigma70_r4_2 PF08281.7 EMD66564.1 - 0.00062 19.1 0.1 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EMD66564.1 - 0.0014 18.2 0.2 0.0046 16.5 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 EMD66564.1 - 0.047 13.0 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3364 PF11844.3 EMD66564.1 - 0.17 11.9 1.5 0.42 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) Catalase PF00199.14 EMD66565.1 - 6.1e-154 512.3 0.1 1e-153 511.6 0.1 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMD66565.1 - 5.5e-19 67.7 0.0 1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Pil1 PF13805.1 EMD66566.1 - 5.4e-96 320.9 6.2 8.5e-96 320.2 4.3 1.3 1 1 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EMD66566.1 - 0.027 13.8 1.4 0.045 13.0 1.0 1.4 1 0 0 1 1 1 0 FAM92 protein Birna_RdRp PF04197.7 EMD66566.1 - 0.03 12.3 3.6 0.04 11.9 2.5 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF3452 PF11934.3 EMD66566.1 - 0.068 12.4 0.8 0.12 11.6 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Seryl_tRNA_N PF02403.17 EMD66566.1 - 2.2 8.3 9.3 1.8 8.6 3.2 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Sec23_trunk PF04811.10 EMD66567.1 - 6e-64 215.7 0.0 1.1e-63 214.8 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMD66567.1 - 7.3e-23 79.9 0.0 2e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EMD66567.1 - 5.1e-18 64.3 5.2 9.5e-18 63.4 3.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EMD66567.1 - 2.6e-17 63.1 0.0 6.4e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EMD66567.1 - 3e-08 33.2 0.0 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-H2C2_2 PF13465.1 EMD66570.1 - 6.8e-06 26.1 4.0 6.8e-06 26.1 2.8 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMD66570.1 - 2.6e-05 24.3 11.4 0.0089 16.3 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD66570.1 - 2.7e-05 24.1 12.5 0.0043 17.2 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Drc1-Sld2 PF11719.3 EMD66571.1 - 6.1e-90 302.3 14.5 6.1e-90 302.3 10.0 2.0 2 0 0 2 2 2 1 DNA replication and checkpoint protein SAC3_GANP PF03399.11 EMD66571.1 - 1.7e-27 96.3 0.0 1.1e-26 93.6 0.0 2.2 1 1 1 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMD66571.1 - 3.3e-21 75.5 0.0 9.5e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Pyr_redox_2 PF07992.9 EMD66572.1 - 1.9e-40 138.9 0.2 5.8e-40 137.3 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMD66572.1 - 2e-39 133.9 0.5 6.7e-39 132.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMD66572.1 - 1e-23 83.4 9.5 1.4e-19 70.2 1.1 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MIF4G PF02854.14 EMD66572.1 - 3.3e-23 82.2 0.9 5.9e-22 78.1 0.1 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EMD66572.1 - 2.3e-21 75.5 0.0 7e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 MA3 domain NAD_binding_8 PF13450.1 EMD66572.1 - 9.3e-10 38.3 6.0 7.8e-06 25.8 0.5 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMD66572.1 - 6e-09 35.2 7.7 7e-08 31.7 1.2 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMD66572.1 - 1.2e-08 34.4 0.3 1.2e-08 34.4 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD66572.1 - 1.6e-08 34.8 1.1 0.00038 20.5 0.7 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD66572.1 - 1.1e-07 31.1 13.7 4.5e-05 22.5 0.3 4.0 4 0 0 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD66572.1 - 6.7e-07 28.5 7.5 1.5e-06 27.3 2.4 2.8 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMD66572.1 - 3e-05 23.6 2.6 0.14 11.6 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMD66572.1 - 0.0001 21.4 3.3 0.00013 21.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EMD66572.1 - 0.00011 21.3 1.2 0.23 10.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMD66572.1 - 0.00026 19.5 2.8 0.00026 19.5 1.9 4.0 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 EMD66572.1 - 0.012 15.9 1.2 5.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EMD66572.1 - 0.012 14.6 11.9 0.18 10.8 1.2 3.0 2 1 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EMD66572.1 - 0.11 11.6 1.1 5 6.2 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EMD66572.1 - 0.17 10.9 0.9 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EMD66572.1 - 0.26 10.9 9.6 0.037 13.6 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain alpha-hel2 PF14456.1 EMD66572.1 - 0.33 9.6 8.3 0.18 10.5 0.5 2.6 2 0 0 2 2 2 0 Alpha-helical domain 2 Lycopene_cycl PF05834.7 EMD66572.1 - 1.1 8.1 7.5 0.14 11.0 0.6 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMD66572.1 - 1.5 7.3 7.1 0.21 10.2 1.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase SRP14 PF02290.10 EMD66573.1 - 9.5e-22 76.7 1.5 1e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF4449 PF14613.1 EMD66573.1 - 0.0055 16.6 1.7 0.007 16.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DOPA_dioxygen PF08883.6 EMD66574.1 - 2.4e-35 120.7 0.0 2.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family tRNA-synt_2 PF00152.15 EMD66575.1 - 2.5e-70 236.9 0.8 3.3e-70 236.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMD66575.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_L22 PF00237.14 EMD66575.1 - 0.65 9.9 5.7 9.9 6.1 2.1 2.9 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e Spore_coat_CotO PF14153.1 EMD66575.1 - 1.5 8.2 10.1 14 5.0 7.0 2.1 1 1 0 1 1 1 0 Spore coat protein CotO PHD PF00628.24 EMD66576.1 - 2.5e-12 46.2 25.3 4.6e-08 32.6 7.7 2.6 2 0 0 2 2 2 2 PHD-finger Peptidase_M24 PF00557.19 EMD66576.1 - 1.3e-09 37.9 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 C1_1 PF00130.17 EMD66576.1 - 0.057 13.1 17.8 0.036 13.7 3.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EMD66576.1 - 1.9 8.6 13.1 0.69 10.0 3.2 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF963 PF06131.6 EMD66576.1 - 3.1 7.1 11.8 0.026 13.7 1.0 2.9 2 1 1 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) SNF5 PF04855.7 EMD66577.1 - 2.8e-74 249.6 1.2 4.8e-74 248.8 0.8 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TFIIA_gamma_N PF02268.11 EMD66577.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain GPP34 PF05719.6 EMD66578.1 - 1.1e-64 218.2 0.1 1.4e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EMD66579.1 - 2.6e-11 43.5 0.2 3.9e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMD66579.1 - 5.1e-08 32.8 0.1 9.2e-08 32.0 0.1 1.4 2 0 0 2 2 2 1 Acyl-carrier DUF1493 PF07377.7 EMD66579.1 - 0.1 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 EMD66579.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Ribosomal subunit 39S Fer4 PF00037.22 EMD66580.1 - 3.2e-14 51.8 15.8 1.8e-08 33.6 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMD66580.1 - 2.2e-12 47.1 10.1 3.3e-12 46.5 7.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMD66580.1 - 1.3e-10 41.8 7.2 5e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EMD66580.1 - 3.1e-10 39.6 22.2 3.8e-08 33.0 8.6 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMD66580.1 - 5.8e-10 39.2 10.5 1e-09 38.4 7.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EMD66580.1 - 2.8e-09 36.6 22.2 1.1e-06 28.4 8.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMD66580.1 - 2.3e-08 33.9 20.2 1.9e-06 27.7 7.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMD66580.1 - 5.6e-08 32.2 14.0 0.00028 20.6 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EMD66580.1 - 2.2e-07 30.4 16.6 0.0013 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EMD66580.1 - 8.2e-07 28.8 11.5 0.00033 20.7 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EMD66580.1 - 1.6e-05 25.1 11.2 0.00017 21.8 8.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMD66580.1 - 3.9e-05 23.9 10.0 0.029 14.7 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EMD66580.1 - 0.0033 17.7 15.7 0.29 11.5 2.0 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EMD66580.1 - 0.0038 17.7 13.3 0.26 11.8 1.1 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EMD66580.1 - 0.0084 16.6 17.4 0.018 15.5 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EMD66580.1 - 0.29 11.2 4.7 0.43 10.7 0.1 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 EMD66581.1 - 3.1e-46 157.3 48.7 3.1e-46 157.3 33.8 3.7 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EMD66581.1 - 1.5e-19 69.8 0.9 1.5e-19 69.8 0.6 8.8 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 Rb_C PF08934.5 EMD66582.1 - 0.023 14.3 0.2 0.073 12.7 0.1 1.8 1 0 0 1 1 1 0 Rb C-terminal domain MIT PF04212.13 EMD66585.1 - 6.4e-10 38.7 1.1 6.4e-10 38.7 0.8 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain PCI PF01399.22 EMD66586.1 - 3.9e-06 27.1 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 EMD66586.1 - 0.00037 20.0 2.7 0.2 11.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Flagellin_C PF00700.16 EMD66586.1 - 0.15 12.2 1.7 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region TPR_16 PF13432.1 EMD66586.1 - 0.63 10.7 5.8 3.4 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMD66587.1 - 1.4e-43 147.7 2.2 2.2e-43 147.0 0.8 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EMD66587.1 - 2.2e-18 66.3 0.0 3.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66587.1 - 7.4e-08 31.7 0.2 3.4e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD66587.1 - 0.051 13.2 0.0 0.051 13.2 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD66587.1 - 0.14 11.0 0.1 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ADH_zinc_N PF00107.21 EMD66588.1 - 4.2e-26 91.0 0.1 6.9e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD66588.1 - 1.7e-19 69.5 2.8 1.7e-19 69.5 2.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD66588.1 - 8.6e-05 23.4 0.0 0.00016 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMD66588.1 - 0.002 17.7 1.3 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMD66588.1 - 0.0029 16.7 0.1 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMD66588.1 - 0.0045 16.9 0.1 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_31 PF13847.1 EMD66588.1 - 0.0063 16.1 0.2 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 EMD66588.1 - 0.018 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMD66588.1 - 0.019 14.3 0.2 0.033 13.5 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMD66588.1 - 0.033 14.7 0.0 0.23 12.0 0.0 2.2 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMD66588.1 - 0.1 13.1 0.4 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_15 PF00723.16 EMD66590.1 - 1.7e-53 181.8 0.0 3.8e-51 174.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TP_methylase PF00590.15 EMD66591.1 - 1.1e-21 77.5 0.3 1.9e-21 76.7 0.2 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EMD66592.1 - 1.6e-26 91.8 0.2 6.9e-26 89.8 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Ribosomal_L19e PF01280.15 EMD66593.1 - 1.3e-56 190.5 8.5 1.3e-56 190.5 5.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L19e FUSC_2 PF13515.1 EMD66593.1 - 1.3e-28 99.4 6.5 1.3e-28 99.4 4.5 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EMD66593.1 - 6.1e-10 38.3 10.9 0.0049 15.5 0.0 4.4 4 0 0 4 4 4 3 Aluminium activated malate transporter FUSC PF04632.7 EMD66593.1 - 3.5e-06 25.7 8.8 0.00013 20.5 2.4 3.0 2 1 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EMD66593.1 - 0.00081 19.0 0.5 0.0041 16.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) MPLKIP PF15502.1 EMD66594.1 - 0.00029 21.5 0.3 0.00065 20.4 0.2 1.8 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein DUF1777 PF08648.7 EMD66594.1 - 0.06 13.0 0.7 0.15 11.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) KxDL PF10241.4 EMD66595.1 - 2.9e-31 107.2 0.3 3.7e-31 106.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF1373 PF07117.6 EMD66595.1 - 4.7 6.8 10.9 0.45 10.2 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1373) AAA PF00004.24 EMD66596.1 - 1.2e-55 187.2 0.0 1.1e-39 135.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EMD66596.1 - 8.4e-11 41.3 0.2 1.8e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 EMD66596.1 - 5.7e-10 39.0 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EMD66596.1 - 9.6e-10 38.7 0.1 0.0016 18.5 0.0 3.6 2 2 1 3 3 2 2 AAA domain AAA_5 PF07728.9 EMD66596.1 - 3.5e-09 36.5 0.2 0.0012 18.6 0.1 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD66596.1 - 1.7e-08 34.7 0.0 0.0021 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EMD66596.1 - 3e-08 33.2 0.2 0.0067 16.1 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EMD66596.1 - 3.3e-08 33.5 0.0 0.00089 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMD66596.1 - 6.9e-08 33.3 0.0 0.019 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMD66596.1 - 1.8e-07 30.2 0.0 0.0045 15.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EMD66596.1 - 2.9e-07 30.4 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EMD66596.1 - 3.7e-07 29.4 0.1 0.029 13.4 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EMD66596.1 - 3.8e-07 29.4 0.1 0.004 16.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMD66596.1 - 1.6e-06 28.2 0.0 0.05 13.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EMD66596.1 - 1.7e-06 28.3 0.1 0.091 13.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EMD66596.1 - 2.1e-06 27.7 0.0 0.00013 21.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMD66596.1 - 6.6e-06 25.6 0.1 0.07 12.5 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_24 PF13479.1 EMD66596.1 - 7.1e-06 25.7 0.5 0.068 12.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EMD66596.1 - 9.2e-06 25.4 0.3 0.013 15.1 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Arch_ATPase PF01637.13 EMD66596.1 - 1.2e-05 25.1 0.2 0.23 11.1 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase KaiC PF06745.8 EMD66596.1 - 2.9e-05 23.3 0.1 0.013 14.6 0.0 2.7 2 1 0 2 2 2 1 KaiC AAA_25 PF13481.1 EMD66596.1 - 3.2e-05 23.4 1.4 0.55 9.5 0.1 3.8 2 2 2 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EMD66596.1 - 9.6e-05 21.9 0.0 0.24 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EMD66596.1 - 0.00015 20.9 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EMD66596.1 - 0.00015 21.7 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMD66596.1 - 0.00041 19.9 0.0 0.077 12.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain PhoH PF02562.11 EMD66596.1 - 0.00045 19.5 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein KTI12 PF08433.5 EMD66596.1 - 0.00094 18.4 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_11 PF13086.1 EMD66596.1 - 0.0013 18.3 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EMD66596.1 - 0.0015 18.5 0.1 0.82 9.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EMD66596.1 - 0.0019 17.8 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EMD66596.1 - 0.0024 18.1 0.1 0.3 11.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 EMD66596.1 - 0.0049 16.5 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EMD66596.1 - 0.0058 15.5 0.1 2.2 7.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 EMD66596.1 - 0.007 15.3 0.1 1.9 7.3 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EMD66596.1 - 0.027 14.3 0.0 8.5 6.1 0.0 2.6 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD66596.1 - 0.049 13.1 0.1 39 3.6 0.0 3.8 2 2 0 4 4 4 0 DEAD/DEAH box helicase cobW PF02492.14 EMD66596.1 - 0.052 12.9 0.1 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EMD66596.1 - 0.059 12.5 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF4220 PF13968.1 EMD66596.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SRP54 PF00448.17 EMD66596.1 - 0.067 12.6 0.0 3 7.2 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Parvo_NS1 PF01057.12 EMD66596.1 - 0.068 12.0 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Zot PF05707.7 EMD66596.1 - 0.089 12.2 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.13 EMD66596.1 - 0.2 11.1 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase WD40 PF00400.27 EMD66597.1 - 5.3e-18 64.1 10.6 4.3e-05 23.2 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CDC45 PF02724.9 EMD66597.1 - 0.96 7.4 14.8 1.3 7.0 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EMD66597.1 - 3.7 6.8 15.3 8.1 5.7 10.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MscL PF01741.13 EMD66599.1 - 9.8e-15 54.8 1.4 2.1e-14 53.7 1.0 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL GTP_EFTU_D3 PF03143.12 EMD66599.1 - 0.1 12.8 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain DZR PF12773.2 EMD66599.1 - 0.16 11.8 1.6 0.28 11.0 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EMD66599.1 - 0.29 10.6 2.1 0.59 9.6 1.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 EMD66600.1 - 1.1e-27 97.4 0.0 2e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD66600.1 - 5.4e-14 52.2 0.0 2.3e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD66600.1 - 4.5e-10 39.4 0.0 2.4e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMD66600.1 - 9.9e-07 27.5 0.0 1.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family EthD PF07110.6 EMD66600.1 - 3.5e-06 27.8 0.1 0.026 15.4 0.0 3.0 2 0 0 2 2 2 2 EthD domain Esterase PF00756.15 EMD66600.1 - 0.00028 20.3 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Lactonase PF10282.4 EMD66601.1 - 3.8e-13 49.2 0.0 8.1e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 EMD66602.1 - 2.6e-46 157.2 0.0 4.3e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Acyl-CoA_dh_1 PF00441.19 EMD66602.1 - 1.1e-41 142.4 0.5 2.1e-41 141.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD66602.1 - 1.8e-33 115.4 0.1 4.8e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMD66602.1 - 2.9e-17 61.8 0.1 5.6e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD66602.1 - 1.9e-15 57.3 0.0 5.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Dioxygenase_N PF04444.9 EMD66602.1 - 2.8e-13 49.6 0.0 6.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CMD PF02627.15 EMD66602.1 - 3.4e-09 36.3 0.0 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family HpaB_N PF11794.3 EMD66602.1 - 0.00014 21.3 0.4 0.0006 19.2 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CarboxypepD_reg PF13620.1 EMD66602.1 - 0.067 13.2 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain TPR_11 PF13414.1 EMD66604.1 - 1.8e-12 46.7 5.9 5.9e-09 35.4 1.3 3.2 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMD66604.1 - 2.2e-09 36.5 2.0 0.0007 19.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD66604.1 - 5.3e-07 29.0 2.4 0.26 11.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD66604.1 - 0.0093 16.6 1.2 0.03 15.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD66604.1 - 0.049 13.7 2.0 0.077 13.1 0.7 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMD66604.1 - 0.059 13.1 0.3 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 EMD66604.1 - 0.078 12.8 1.3 6.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus TPR_14 PF13428.1 EMD66604.1 - 0.1 13.2 0.4 3.6 8.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66604.1 - 0.15 12.0 3.1 0.55 10.2 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Mcp5_PH PF12814.2 EMD66605.1 - 2.2e-43 147.1 0.0 5.2e-43 145.8 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology AMP-binding PF00501.23 EMD66606.1 - 7.3e-78 261.8 0.0 9.4e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD66606.1 - 7.4e-14 52.4 0.1 2.6e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1230 PF06799.6 EMD66607.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) SHMT PF00464.14 EMD66608.1 - 4e-199 661.0 0.0 4.7e-199 660.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MAD PF05557.8 EMD66610.1 - 3.4e-61 207.2 70.1 6.6e-61 206.3 48.6 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein Seryl_tRNA_N PF02403.17 EMD66610.1 - 0.0047 16.9 9.8 0.0047 16.9 6.8 7.0 2 2 2 6 6 6 2 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 EMD66610.1 - 1 8.4 21.2 2.4 7.2 2.8 4.5 2 2 2 4 4 4 0 Reovirus sigma C capsid protein LCM PF04072.9 EMD66611.1 - 2e-23 82.9 0.0 3.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase RNA_pol_Rpb5_C PF01191.14 EMD66612.1 - 2.5e-35 119.9 0.3 3.7e-35 119.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EMD66612.1 - 2.9e-30 104.5 0.1 4.5e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain LigT_PEase PF02834.11 EMD66613.1 - 0.11 12.5 0.1 0.85 9.6 0.1 2.4 3 0 0 3 3 3 0 LigT like Phosphoesterase SKG6 PF08693.5 EMD66614.1 - 0.022 14.0 3.5 0.035 13.4 2.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3505 PF12013.3 EMD66614.1 - 0.035 14.3 0.1 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) TarH PF02203.10 EMD66614.1 - 0.089 12.6 1.5 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue CcmD PF04995.9 EMD66614.1 - 0.18 11.5 3.6 0.35 10.6 2.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MLANA PF14991.1 EMD66615.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A SKG6 PF08693.5 EMD66615.1 - 0.013 14.7 0.9 0.024 13.9 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Collagen PF01391.13 EMD66615.1 - 0.047 13.2 9.7 0.11 12.1 6.7 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF3529 PF12046.3 EMD66615.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Tim54 PF11711.3 EMD66617.1 - 0.026 13.1 0.4 0.028 13.0 0.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BLVR PF06375.6 EMD66617.1 - 0.043 13.6 5.3 0.05 13.4 3.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EMD66617.1 - 0.064 13.0 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 EMD66617.1 - 0.087 12.4 9.5 0.1 12.2 6.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EMD66617.1 - 0.11 11.6 3.0 0.13 11.4 2.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NST1 PF13945.1 EMD66617.1 - 0.42 10.6 4.3 0.54 10.3 3.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator YihI PF04220.7 EMD66617.1 - 0.61 9.3 6.8 0.82 8.9 4.7 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) BRF1 PF07741.8 EMD66617.1 - 1.3 9.3 7.1 1.8 8.8 5.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain TSGP1 PF07771.6 EMD66617.1 - 2.7 7.9 7.7 3.8 7.3 5.3 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 Herpes_DNAp_acc PF04929.7 EMD66617.1 - 3.8 6.3 6.5 5.6 5.8 4.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2413 PF10310.4 EMD66617.1 - 3.9 6.1 6.1 4.6 5.9 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AA_permease PF00324.16 EMD66619.1 - 2.2e-124 415.4 50.9 2.7e-124 415.1 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMD66619.1 - 3.7e-31 108.1 56.7 4.4e-31 107.8 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease zf-LITAF-like PF10601.4 EMD66619.1 - 0.057 13.2 1.3 4.1 7.3 0.0 3.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Hydrophobin_2 PF06766.6 EMD66620.1 - 1.6e-22 78.9 10.5 2e-22 78.6 7.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Defensin_beta PF00711.14 EMD66620.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.2 2 0 0 2 2 2 0 Beta defensin Dicty_CAD PF05720.7 EMD66621.1 - 0.07 12.7 0.4 0.18 11.4 0.3 1.7 1 0 0 1 1 1 0 Cell-cell adhesion domain ApbA_C PF08546.6 EMD66622.1 - 1e-30 106.2 0.4 1.5e-30 105.7 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMD66622.1 - 7.1e-26 90.4 0.0 1e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA zf-UBR PF02207.15 EMD66625.1 - 6.7e-19 67.3 13.6 2e-18 65.8 9.4 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EMD66625.1 - 4.4e-05 23.1 0.2 0.0001 21.9 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EMD66625.1 - 0.00035 20.3 1.0 0.00035 20.3 0.7 4.4 4 1 1 5 5 5 1 Ring finger domain Nop14 PF04147.7 EMD66625.1 - 1.4 6.7 5.2 2.3 6.0 3.6 1.2 1 0 0 1 1 1 0 Nop14-like family CAP_N PF01213.14 EMD66625.1 - 1.6 7.9 6.7 3.3 6.8 4.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.7 EMD66626.1 - 3e-22 77.9 0.5 3.4e-22 77.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EMD66627.1 - 1.2e-14 53.5 4.2 2.3e-14 52.6 2.9 1.5 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 EMD66627.1 - 0.19 11.6 12.9 0.22 11.3 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EMD66627.1 - 0.33 10.7 5.4 0.39 10.4 3.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF506 PF04720.7 EMD66627.1 - 0.4 10.2 3.4 0.55 9.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PAPS_reduct PF01507.14 EMD66627.1 - 0.46 10.2 2.0 0.68 9.7 1.4 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2201_N PF13203.1 EMD66627.1 - 4.1 6.4 9.3 5 6.2 6.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SWI-SNF_Ssr4 PF08549.5 EMD66629.1 - 6.1e-138 461.0 40.6 5.7e-135 451.2 28.1 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Acyl_transf_3 PF01757.17 EMD66630.1 - 9.9e-17 60.7 20.6 1.4e-16 60.2 14.3 1.3 1 0 0 1 1 1 1 Acyltransferase family Band_7 PF01145.20 EMD66631.1 - 1.8e-28 99.6 3.2 1.8e-28 99.6 2.2 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Dak1_2 PF13684.1 EMD66631.1 - 0.015 14.2 1.5 0.021 13.7 1.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Band_7_1 PF13421.1 EMD66631.1 - 0.024 14.1 0.3 0.045 13.2 0.2 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Reo_sigmaC PF04582.7 EMD66632.1 - 0.0046 16.1 17.2 0.054 12.6 1.7 2.7 2 1 1 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 EMD66632.1 - 7.7 5.8 79.2 0.24 10.8 20.8 4.6 1 1 4 5 5 5 0 Intermediate filament protein NPV_P10 PF05531.7 EMD66632.1 - 8.5 6.7 18.8 1.1 9.5 0.2 5.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein OST3_OST6 PF04756.8 EMD66633.1 - 9.7e-21 73.9 1.4 1.4e-20 73.4 1.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EMD66633.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin QCR10 PF09796.4 EMD66633.1 - 0.21 11.2 1.7 6.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4449 PF14613.1 EMD66634.1 - 4.2e-05 23.5 0.2 4.2e-05 23.5 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 EMD66634.1 - 0.0086 15.7 0.1 0.056 13.0 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function DUF1828 Malic_M PF03949.10 EMD66635.1 - 8.1e-86 287.7 0.0 1e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMD66635.1 - 5.8e-62 208.5 0.0 1.1e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AT_hook PF02178.14 EMD66636.1 - 0.061 13.0 5.8 0.061 13.0 4.0 2.7 3 0 0 3 3 3 0 AT hook motif IER PF05760.7 EMD66636.1 - 0.11 12.3 3.9 0.13 12.1 2.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) FSH1 PF03959.8 EMD66636.1 - 0.14 11.6 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF3275 PF11679.3 EMD66636.1 - 0.44 10.1 3.4 0.56 9.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) eIF-3c_N PF05470.7 EMD66636.1 - 0.61 8.1 5.0 0.73 7.8 3.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Patatin PF01734.17 EMD66638.1 - 1.4e-24 87.1 0.0 2.3e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase ApbA_C PF08546.6 EMD66639.1 - 2.3e-27 95.4 0.0 3.2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMD66639.1 - 2.2e-24 85.6 0.0 2.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EMD66639.1 - 0.0018 17.6 0.1 0.053 12.8 0.1 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EMD66639.1 - 0.0048 17.1 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ThiF PF00899.16 EMD66639.1 - 0.036 13.8 1.2 0.84 9.4 1.3 2.2 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.14 EMD66639.1 - 0.069 12.1 0.6 0.094 11.7 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EMD66639.1 - 0.095 12.7 0.3 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMD66639.1 - 0.12 12.4 0.9 0.24 11.4 0.6 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMD66639.1 - 0.17 10.7 1.3 1.5 7.5 1.9 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EMD66639.1 - 0.59 8.9 3.6 0.95 8.2 2.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_L44 PF00935.14 EMD66640.1 - 5.4e-35 119.2 11.1 8.3e-35 118.6 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2652 PF10851.3 EMD66640.1 - 1.8 8.5 4.1 0.44 10.5 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2652) MSC PF09402.5 EMD66641.1 - 9.3e-84 280.9 0.0 1.2e-83 280.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EMD66641.1 - 9.1e-14 50.7 0.0 1.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Polysacc_lyase PF14099.1 EMD66642.1 - 0.00035 20.3 7.3 0.00045 19.9 5.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase DUF2457 PF10446.4 EMD66643.1 - 0.079 11.6 5.5 0.098 11.3 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Patatin PF01734.17 EMD66644.1 - 9.7e-26 90.9 1.5 1e-24 87.6 0.5 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase Inp1 PF12634.2 EMD66646.1 - 3e-33 114.5 0.0 6.5e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EMD66647.1 - 4.7e-08 32.7 6.3 1.6e-06 27.7 4.3 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.10 EMD66648.1 - 5.5e-156 518.8 0.0 6.9e-156 518.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Redoxin PF08534.5 EMD66649.1 - 3.2e-28 98.1 0.0 3.6e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMD66649.1 - 5.4e-06 26.1 0.0 6.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EMD66650.1 - 9.7e-37 125.2 0.4 9.7e-37 125.2 0.3 2.5 2 0 0 2 2 1 1 HSF-type DNA-binding Response_reg PF00072.19 EMD66650.1 - 1.4e-21 76.6 0.0 2.8e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain zf-DHHC PF01529.15 EMD66650.1 - 0.043 13.2 0.3 0.08 12.3 0.2 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_23 PF13476.1 EMD66650.1 - 0.087 13.1 12.6 0.034 14.4 6.8 1.7 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.7 EMD66650.1 - 0.089 12.6 10.8 0.22 11.4 7.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 EMD66650.1 - 0.091 12.0 39.5 0.011 15.0 23.6 2.0 2 0 0 2 2 2 0 SprA-related family FLO_LFY PF01698.11 EMD66650.1 - 0.15 10.8 12.4 0.29 9.9 8.6 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4557 PF15101.1 EMD66650.1 - 0.6 9.9 25.1 1.5 8.6 17.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DDHD PF02862.12 EMD66650.1 - 1.3 8.8 15.5 0.26 11.0 8.0 1.8 2 0 0 2 2 2 0 DDHD domain OmpH PF03938.9 EMD66650.1 - 2.4 8.0 36.4 0.025 14.5 19.5 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0560 PF10577.4 EMD66650.1 - 2.5 6.2 23.8 0.2 9.8 12.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF1764 PF08576.5 EMD66650.1 - 5.3 7.8 17.6 17 6.2 12.2 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) W2 PF02020.13 EMD66651.1 - 2.4e-11 43.4 12.9 9.4e-11 41.5 8.9 2.1 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EMD66651.1 - 4.5e-11 41.7 13.0 0.00012 21.3 0.6 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD66651.1 - 8.6e-09 34.8 10.0 0.008 15.7 0.3 3.5 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EMD66651.1 - 1.5e-06 27.7 0.0 2.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMD66651.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 EMD66651.1 - 0.013 15.1 1.0 1.7 8.2 0.0 2.5 2 1 0 2 2 2 0 Cytidylyltransferase Fucokinase PF07959.7 EMD66651.1 - 0.16 10.5 1.4 0.45 9.0 0.2 2.0 1 1 1 2 2 2 0 L-fucokinase IBR PF01485.16 EMD66652.1 - 1.4e-24 85.7 44.9 5.7e-13 48.5 5.1 4.6 3 1 1 4 4 4 4 IBR domain zf-C3HC4_2 PF13923.1 EMD66652.1 - 3e-06 27.1 6.6 3e-06 27.1 4.6 4.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD66652.1 - 6.1e-05 22.5 4.4 6.1e-05 22.5 3.0 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD66652.1 - 0.0001 22.0 4.2 0.0001 22.0 2.9 3.7 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EMD66652.1 - 0.0084 15.8 6.8 0.0084 15.8 4.7 4.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMD66652.1 - 0.081 12.8 32.2 0.12 12.2 2.6 4.6 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING Trp_syntA PF00290.15 EMD66652.1 - 0.093 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DNA_ligase_ZBD PF03119.11 EMD66652.1 - 1.4 8.6 13.1 1.2 8.8 0.2 3.0 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Fijivirus_P9-2 PF06837.6 EMD66653.1 - 2.5 7.1 9.4 2.8 7.0 6.5 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein Peptidase_S8 PF00082.17 EMD66654.1 - 1.5e-52 178.5 15.1 2e-52 178.1 10.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD66654.1 - 2.1e-18 66.6 0.9 2.1e-18 66.6 0.6 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Beach PF02138.13 EMD66655.1 - 2.5e-108 361.6 0.4 4.7e-108 360.7 0.2 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EMD66655.1 - 1.9e-11 43.7 0.4 2e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EMD66655.1 - 4.8e-09 36.6 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EMD66655.1 - 1.5e-08 34.1 0.0 0.017 14.9 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3513 PF12026.3 EMD66655.1 - 0.28 10.6 3.0 0.63 9.5 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Fungal_trans PF04082.13 EMD66656.1 - 3e-25 88.6 0.4 4.3e-25 88.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66656.1 - 2.1e-15 56.2 30.8 4.2e-08 32.9 5.3 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EMD66657.1 - 2.3e-38 128.6 9.4 3.2e-11 42.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMD66657.1 - 0.0034 17.1 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Nup160 PF11715.3 EMD66657.1 - 0.0053 14.9 3.6 0.33 9.0 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD66657.1 - 0.053 12.2 1.4 4.3 5.9 0.2 2.9 1 1 1 3 3 3 0 Nup133 N terminal like MFS_1 PF07690.11 EMD66658.1 - 2e-31 108.9 33.6 2e-31 108.9 23.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF204 PF02659.10 EMD66658.1 - 10 6.3 12.7 0.51 10.5 1.3 4.2 2 2 3 5 5 5 0 Domain of unknown function DUF ABC_membrane PF00664.18 EMD66659.1 - 5.5e-44 150.6 12.8 7.3e-44 150.2 8.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMD66659.1 - 1.6e-35 122.3 0.0 5.9e-35 120.5 0.0 2.0 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EMD66659.1 - 9.7e-06 24.9 0.0 3.2e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EMD66659.1 - 0.0027 17.8 0.2 0.031 14.4 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD66659.1 - 0.0036 17.4 0.6 0.032 14.3 0.3 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMD66659.1 - 0.0049 16.8 0.1 0.015 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EMD66659.1 - 0.0069 15.8 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EMD66659.1 - 0.0069 15.7 0.3 0.026 13.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EMD66659.1 - 0.013 15.3 0.5 0.098 12.5 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EMD66659.1 - 0.021 14.5 0.5 0.45 10.3 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain ABC_ATPase PF09818.4 EMD66659.1 - 0.027 13.0 0.1 0.044 12.3 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_21 PF13304.1 EMD66659.1 - 0.027 14.4 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMD66659.1 - 0.035 13.5 0.2 0.18 11.2 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.2 EMD66659.1 - 0.057 12.8 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EMD66659.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EMD66659.1 - 0.067 12.9 2.5 0.29 10.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EMD66659.1 - 0.07 13.9 0.2 0.25 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cupin_2 PF07883.6 EMD66660.1 - 1.5e-13 50.0 0.3 3e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMD66660.1 - 7.9e-08 32.0 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMD66660.1 - 6e-06 25.7 0.1 8e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMD66660.1 - 7e-05 22.5 0.1 7.6e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMD66660.1 - 0.00031 20.0 0.2 0.0006 19.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 EMD66660.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding_2 PF14525.1 EMD66660.1 - 0.032 13.8 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain MannoseP_isomer PF01050.13 EMD66660.1 - 0.061 12.9 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase FAD_binding_1 PF00667.15 EMD66661.1 - 1.1e-47 162.3 0.0 1.6e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMD66661.1 - 1.2e-10 41.9 0.0 2.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MOSC PF03473.12 EMD66662.1 - 1.8e-11 43.6 0.0 2.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Allantoicase PF03561.10 EMD66663.1 - 2.1e-101 335.7 0.2 1.4e-55 186.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.2 EMD66664.1 - 1.5e-19 70.1 0.1 2.2e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 EMD66664.1 - 2.3e-19 69.1 5.3 9.3e-13 47.9 0.1 2.8 3 0 0 3 3 3 2 DIL domain Ank PF00023.25 EMD66664.1 - 3.7e-17 61.1 0.0 4.4e-08 32.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD66664.1 - 1.8e-11 44.2 0.1 3.8e-05 24.0 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD66664.1 - 6.7e-11 42.0 0.0 1.7e-09 37.6 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD66664.1 - 1.8e-09 36.8 0.1 1.4e-05 24.8 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Prp18 PF02840.10 EMD66664.1 - 0.083 12.7 0.1 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Prp18 domain HATPase_c PF02518.21 EMD66665.1 - 6.9e-28 96.5 0.0 1.4e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD66665.1 - 6.7e-21 74.0 0.0 4.4e-20 71.4 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EMD66665.1 - 7.4e-18 64.5 0.0 2e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.20 EMD66665.1 - 6e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EMD66665.1 - 1e-08 35.3 1.0 4.3e-08 33.3 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain GAF_3 PF13492.1 EMD66665.1 - 3.9e-08 33.4 0.0 9.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EMD66665.1 - 9.6e-08 32.6 0.0 2.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EMD66665.1 - 2.7e-07 30.8 0.0 9.5e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.1 EMD66665.1 - 0.00022 21.0 4.0 0.0013 18.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Kinase-like PF14531.1 EMD66665.1 - 0.0054 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NACHT PF05729.7 EMD66665.1 - 0.038 13.6 0.5 6.4 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Abhydrolase_6 PF12697.2 EMD66667.1 - 7.2e-36 124.1 0.0 8.3e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD66667.1 - 8.5e-25 87.2 0.0 1.5e-24 86.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD66667.1 - 4.7e-20 72.1 0.0 2.6e-14 53.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMD66667.1 - 5.1e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMD66667.1 - 8.2e-08 31.9 0.0 0.02 14.3 0.0 3.1 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Ndr PF03096.9 EMD66667.1 - 3.3e-06 25.7 0.0 3.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 EMD66667.1 - 0.00054 19.6 0.0 0.0089 15.6 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 EMD66667.1 - 0.00054 20.2 0.0 0.00098 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PAF-AH_p_II PF03403.8 EMD66667.1 - 0.00086 17.6 1.0 0.0044 15.3 0.1 1.9 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 EMD66667.1 - 0.0032 17.0 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EMD66667.1 - 0.0044 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Peptidase_S9 PF00326.16 EMD66667.1 - 0.0066 15.6 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EMD66667.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 EMD66667.1 - 0.02 14.1 0.0 5.5 6.2 0.0 2.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EMD66667.1 - 0.024 13.5 0.3 0.45 9.3 0.2 2.2 1 1 0 1 1 1 0 Chlorophyllase enzyme UPF0261 PF06792.6 EMD66667.1 - 0.035 12.5 0.0 0.05 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Abhydrolase_3 PF07859.8 EMD66667.1 - 0.047 13.2 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Macoilin PF09726.4 EMD66668.1 - 1.1 7.4 5.8 1.3 7.2 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Cyt-b5 PF00173.23 EMD66669.1 - 2.1e-15 56.2 0.1 2.3e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nuclease_act PF08133.6 EMD66669.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Anticodon nuclease activator family BRX PF08381.6 EMD66669.1 - 0.25 10.4 2.1 1.8 7.7 0.6 2.6 2 1 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 VID27 PF08553.5 EMD66670.1 - 0 1104.1 1.1 0 1104.0 0.8 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Fungal_trans PF04082.13 EMD66671.1 - 9.6e-15 54.1 2.1 1.9e-14 53.2 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66671.1 - 5.4e-07 29.4 9.3 1.2e-06 28.3 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMD66672.1 - 7.2e-41 140.0 30.2 7.2e-41 140.0 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD66672.1 - 9.4e-11 40.6 3.4 9.4e-11 40.6 2.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EMD66673.1 - 7e-26 91.1 0.4 1.4e-25 90.1 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD66673.1 - 2.8e-11 43.6 0.2 4e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD66673.1 - 2.2e-08 33.9 1.0 5.4e-07 29.4 0.7 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD66673.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD66673.1 - 0.0034 16.8 0.1 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD66673.1 - 0.045 12.6 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3106 PF11304.3 EMD66674.1 - 0.014 15.8 10.6 0.014 15.8 7.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3106) DUF3584 PF12128.3 EMD66674.1 - 0.18 9.0 30.2 0.27 8.5 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 EMD66674.1 - 0.29 11.1 19.7 2 8.4 1.8 4.6 2 1 3 5 5 5 0 bZIP transcription factor Atg14 PF10186.4 EMD66674.1 - 0.58 9.0 33.8 0.68 8.8 11.5 2.7 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EMD66674.1 - 0.72 9.7 9.5 0.21 11.4 1.1 3.4 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4613 PF15390.1 EMD66674.1 - 0.96 7.5 14.4 2.4 6.2 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) DivIC PF04977.10 EMD66674.1 - 1.8 8.1 27.2 0.067 12.6 0.8 4.6 2 1 2 4 4 4 0 Septum formation initiator Peptidase_C6 PF00851.13 EMD66674.1 - 2.4 6.7 11.2 0.57 8.7 5.1 1.8 1 1 0 1 1 1 0 Helper component proteinase Apt1 PF10351.4 EMD66674.1 - 6.3 5.5 19.8 2.4e+02 0.3 12.4 3.0 2 1 0 2 2 2 0 Golgi-body localisation protein domain DUF4200 PF13863.1 EMD66674.1 - 6.6 6.7 31.8 0.5 10.3 1.2 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 EMD66674.1 - 8 6.8 28.7 96 3.3 0.4 4.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIVA PF05103.8 EMD66674.1 - 8 6.5 29.6 1 9.4 0.8 3.8 2 1 2 4 4 4 0 DivIVA protein TPR_MLP1_2 PF07926.7 EMD66674.1 - 9.1 6.0 30.9 2.9 7.6 9.4 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CSTF2_hinge PF14327.1 EMD66676.1 - 1.5e-29 101.9 1.2 1.5e-29 101.9 0.8 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EMD66676.1 - 6.9e-19 67.2 0.0 1.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66676.1 - 1.2e-15 57.1 0.0 3.2e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66676.1 - 9.4e-11 41.4 0.0 1.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EMD66676.1 - 2e-06 26.9 7.2 2e-06 26.9 5.0 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Cu_amine_oxid PF01179.15 EMD66677.1 - 2.6e-163 543.5 0.1 3.1e-163 543.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EMD66677.1 - 8.4e-16 57.8 0.1 1.8e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EMD66677.1 - 0.00087 19.3 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_61 PF03443.9 EMD66678.1 - 2.8e-43 148.2 0.2 3.5e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EMD66678.1 - 0.057 13.4 0.4 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ABC2_membrane PF01061.19 EMD66680.1 - 1e-45 155.5 35.0 2.7e-26 92.0 10.4 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMD66680.1 - 1e-35 123.0 0.1 9.6e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMD66680.1 - 9.5e-13 48.7 0.1 0.0017 18.3 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EMD66680.1 - 2e-06 27.2 0.0 0.0015 17.8 0.0 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EMD66680.1 - 3.4e-05 23.0 0.0 0.31 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.1 EMD66680.1 - 0.0001 22.1 0.4 0.78 9.7 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EMD66680.1 - 0.00017 20.8 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMD66680.1 - 0.00074 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD66680.1 - 0.0011 18.9 0.1 0.0029 17.6 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 EMD66680.1 - 0.0014 18.0 0.0 0.031 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMD66680.1 - 0.0015 18.6 0.0 0.008 16.3 0.0 2.3 3 0 0 3 3 1 1 AAA domain Arch_ATPase PF01637.13 EMD66680.1 - 0.0023 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EMD66680.1 - 0.0043 16.7 0.0 0.02 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EMD66680.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EMD66680.1 - 0.0089 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMD66680.1 - 0.05 13.0 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMD66680.1 - 0.058 12.8 0.6 0.19 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain PDR_assoc PF08370.6 EMD66680.1 - 0.082 12.4 1.3 0.45 10.0 0.7 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated PDR_CDR PF06422.7 EMD66680.1 - 0.086 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 CDR ABC transporter cobW PF02492.14 EMD66680.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EMD66680.1 - 0.14 11.5 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 EMD66680.1 - 0.16 11.6 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EMD66680.1 - 0.16 12.1 0.1 0.57 10.3 0.1 1.9 2 0 0 2 2 1 0 RNA helicase Miro PF08477.8 EMD66680.1 - 0.18 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein RdRP_1 PF00680.15 EMD66680.1 - 0.26 9.4 0.0 0.42 8.8 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Fungal_trans_2 PF11951.3 EMD66682.1 - 1.8e-52 178.2 0.0 2.5e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66682.1 - 3.1e-09 36.5 11.9 5.3e-09 35.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_43 PF03360.11 EMD66682.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 CPSF100_C PF13299.1 EMD66683.1 - 4.5e-43 147.2 0.0 4.5e-43 147.2 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EMD66683.1 - 3.7e-30 104.4 0.0 1.8e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EMD66683.1 - 6.9e-06 25.7 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase DUF490 PF04357.8 EMD66683.1 - 0.0039 16.3 0.1 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF490) KIAA1328 PF15369.1 EMD66683.1 - 0.0047 16.8 0.3 0.0079 16.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein KIAA1328 Lactamase_B PF00753.22 EMD66683.1 - 0.1 12.2 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily CDC37_N PF03234.9 EMD66684.1 - 1.1e-56 191.9 9.1 1.1e-56 191.9 6.3 2.6 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EMD66684.1 - 8e-47 158.9 0.3 2.7e-46 157.2 0.0 2.1 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EMD66684.1 - 3e-25 87.9 0.9 3e-25 87.9 0.6 2.5 2 1 0 2 2 2 1 Cdc37 C terminal domain V-ATPase_H_N PF03224.9 EMD66684.1 - 0.038 13.0 0.1 0.076 12.1 0.1 1.4 1 0 0 1 1 1 0 V-ATPase subunit H DUF4607 PF15380.1 EMD66684.1 - 0.04 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) CTD_bind PF04818.8 EMD66685.1 - 3.1e-20 72.1 1.8 6.2e-20 71.2 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EMD66685.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 FKBP_N PF01346.13 EMD66685.1 - 0.26 11.3 3.2 0.73 9.8 2.2 1.7 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AAA_13 PF13166.1 EMD66685.1 - 0.43 8.9 7.5 1.7 6.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain Allexi_40kDa PF05549.6 EMD66685.1 - 0.86 8.8 3.4 13 4.9 0.1 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein Clathrin_lg_ch PF01086.12 EMD66686.1 - 7.2e-80 268.1 4.5 8.3e-80 267.9 3.1 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 EMD66686.1 - 0.02 14.4 1.1 0.042 13.3 0.8 1.5 1 0 0 1 1 1 0 Integrase core domain Glyco_hydro_61 PF03443.9 EMD66687.1 - 3.5e-68 229.6 0.3 4.2e-68 229.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease_2 PF13520.1 EMD66689.1 - 3.3e-58 197.2 52.9 3.9e-58 196.9 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD66689.1 - 1.3e-18 66.5 46.9 2.6e-18 65.6 32.5 1.4 1 1 0 1 1 1 1 Amino acid permease Glyco_transf_20 PF00982.16 EMD66691.1 - 1.5e-148 495.2 0.0 2e-148 494.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMD66691.1 - 3.4e-92 307.6 0.0 8.8e-92 306.2 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EMD66691.1 - 0.0011 18.6 0.0 0.062 12.8 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4582 PF15189.1 EMD66691.1 - 0.046 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) PAP_assoc PF03828.14 EMD66692.1 - 9.9e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMD66692.1 - 0.0039 17.4 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EMD66692.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase beta palm UQ_con PF00179.21 EMD66693.1 - 1.6e-51 173.4 0.0 1.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD66693.1 - 6.8e-05 22.6 0.0 7.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD66693.1 - 0.0051 16.7 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMD66693.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_1 PF00441.19 EMD66694.1 - 4.8e-23 81.9 0.3 7.9e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD66694.1 - 1.7e-22 80.1 0.3 3.7e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMD66694.1 - 5.5e-16 57.8 0.0 1.2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD66694.1 - 6.5e-07 29.6 0.3 1e-06 29.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_N PF00752.12 EMD66695.1 - 1.4e-30 105.5 0.0 4.9e-30 103.7 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMD66695.1 - 1.8e-29 101.6 0.8 3.9e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EMD66695.1 - 1.3e-06 28.5 1.1 1.2e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EMD66695.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF3671 PF12420.3 EMD66696.1 - 0.094 12.6 2.6 0.11 12.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function BRCT PF00533.21 EMD66698.1 - 0.0034 17.4 0.0 0.0093 16.0 0.0 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMD66698.1 - 0.015 15.1 1.5 0.034 13.9 0.5 1.9 1 1 1 2 2 2 0 twin BRCT domain PhzC-PhzF PF02567.11 EMD66701.1 - 2.7e-42 144.9 0.1 3.3e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Adaptin_N PF01602.15 EMD66704.1 - 9.8e-147 489.4 7.5 1.3e-146 489.0 5.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMD66704.1 - 7e-26 91.1 2.1 5.9e-24 84.8 0.1 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMD66704.1 - 1.1e-16 60.8 0.4 2.9e-05 24.2 0.0 5.1 1 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EMD66704.1 - 1.9e-10 39.9 7.2 0.009 16.0 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat CLASP_N PF12348.3 EMD66704.1 - 0.00013 21.3 0.2 0.62 9.3 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal UNC45-central PF11701.3 EMD66704.1 - 0.00063 19.4 0.2 0.04 13.5 0.1 2.7 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.1 EMD66704.1 - 0.0084 16.5 4.7 6 7.5 0.0 6.1 7 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 EMD66704.1 - 0.0088 15.8 2.1 48 3.9 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PAP2 PF01569.16 EMD66705.1 - 2.3e-09 36.9 7.1 2.3e-09 36.9 5.0 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EMD66705.1 - 1.9e-07 30.7 6.7 1.9e-07 30.7 4.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily Mito_carr PF00153.22 EMD66707.1 - 1.6e-48 162.3 4.7 1.8e-18 66.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EMD66708.1 - 1.1e-52 175.5 0.0 3.7e-17 61.7 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66708.1 - 3.2e-41 139.1 0.0 1.1e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66708.1 - 2.3e-22 78.5 0.0 4.7e-06 26.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD66708.1 - 4.7e-05 23.0 0.0 0.98 9.2 0.0 3.3 3 1 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 EMD66708.1 - 0.00065 19.5 0.0 2 8.3 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif ATP-grasp_2 PF08442.5 EMD66708.1 - 0.057 12.7 0.0 0.85 8.9 0.0 2.6 3 0 0 3 3 3 0 ATP-grasp domain YoaP PF14268.1 EMD66708.1 - 0.76 9.0 3.4 6.2 6.1 0.0 2.9 3 0 0 3 3 3 0 YoaP-like THRAP3_BCLAF1 PF15440.1 EMD66708.1 - 1.7 7.1 26.0 2.3 6.7 18.0 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family AMP-binding PF00501.23 EMD66709.1 - 5.9e-91 304.9 0.0 7.3e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD66709.1 - 3.2e-11 43.9 1.1 7.1e-11 42.8 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCCH PF00642.19 EMD66710.1 - 3.9e-08 32.7 10.9 0.00011 21.8 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pex14_N PF04695.8 EMD66711.1 - 0.068 13.2 2.2 0.69 9.9 1.5 2.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 EMD66712.1 - 8.2e-07 28.6 1.5 0.034 14.0 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Acetyltransf_7 PF13508.1 EMD66713.1 - 8.8e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD66713.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD66713.1 - 7.1e-05 22.9 0.0 0.00027 21.0 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD66713.1 - 0.0019 18.0 0.0 0.067 13.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD66713.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Elongin_A PF06881.6 EMD66714.1 - 6.4e-29 100.5 1.5 1e-28 99.8 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Exonuc_V_gamma PF04257.9 EMD66714.1 - 0.037 12.0 0.2 0.055 11.4 0.2 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit THOC7 PF05615.8 EMD66715.1 - 5.3e-32 110.9 4.8 5.3e-32 110.9 3.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DivIC PF04977.10 EMD66715.1 - 0.0035 16.7 1.3 0.0035 16.7 0.9 3.2 2 1 1 3 3 3 1 Septum formation initiator FliL PF03748.9 EMD66715.1 - 0.2 11.6 1.8 0.35 10.9 0.9 1.7 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL TBCA PF02970.11 EMD66716.1 - 1.4e-23 82.7 12.3 1.7e-23 82.4 8.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mnd1 PF03962.10 EMD66716.1 - 0.033 13.8 9.4 0.043 13.4 6.5 1.2 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 EMD66716.1 - 0.044 12.1 7.4 0.051 11.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2959 PF11172.3 EMD66716.1 - 0.25 11.0 5.6 0.3 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) IncA PF04156.9 EMD66716.1 - 0.81 9.2 7.5 1.1 8.8 5.2 1.3 1 0 0 1 1 1 0 IncA protein SpoIIIAH PF12685.2 EMD66716.1 - 1 8.8 11.1 1.2 8.5 7.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CHD5 PF04420.9 EMD66716.1 - 1.1 8.8 5.5 5.4 6.6 3.8 1.9 1 1 0 1 1 1 0 CHD5-like protein V_ATPase_I PF01496.14 EMD66716.1 - 1.1 6.9 4.7 1.3 6.7 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2570 PF10828.3 EMD66716.1 - 2.1 7.9 8.2 2.6 7.6 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF4164 PF13747.1 EMD66716.1 - 3.8 7.7 9.8 0.97 9.6 1.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Bap31 PF05529.7 EMD66716.1 - 4.1 6.8 11.7 20 4.5 8.1 1.8 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4398 PF14346.1 EMD66716.1 - 6.9 6.7 17.5 2 8.4 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) MCM PF00493.18 EMD66717.1 - 6.3e-139 462.3 0.0 8.5e-139 461.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMD66717.1 - 2.7e-24 85.9 0.0 1.7e-23 83.3 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EMD66717.1 - 5.5e-06 26.1 0.1 2.6e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMD66717.1 - 9.7e-06 24.8 0.0 0.00023 20.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMD66717.1 - 0.00042 19.9 0.0 0.0014 18.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMD66717.1 - 0.058 12.8 0.1 3 7.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DSX_dimer PF08828.5 EMD66717.1 - 3 7.4 8.8 0.37 10.3 0.1 3.5 4 0 0 4 4 4 0 Doublesex dimerisation domain CBM-like PF14683.1 EMD66718.1 - 4.2e-40 137.1 0.1 8.7e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMD66718.1 - 4.9e-23 81.0 0.1 1.5e-22 79.5 0.1 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMD66718.1 - 1.5e-06 28.1 0.3 8.8e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 EMD66718.1 - 0.0081 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) GETHR PF05671.6 EMD66718.1 - 0.12 11.5 0.4 0.28 10.3 0.3 1.6 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) Vac7 PF12751.2 EMD66719.1 - 7.1e-98 327.9 15.6 2.4e-88 296.6 3.9 3.1 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 SSF PF00474.12 EMD66724.1 - 7.7e-18 64.3 30.6 1.3e-17 63.5 21.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DEAD PF00270.24 EMD66726.1 - 1.5e-37 128.7 0.3 2.7e-37 127.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD66726.1 - 3.2e-21 74.9 0.1 3.7e-10 39.5 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 EMD66726.1 - 0.00058 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EMD66726.1 - 0.0011 18.8 1.6 0.0053 16.6 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PAP2 PF01569.16 EMD66727.1 - 0.037 13.7 0.3 0.049 13.3 0.2 1.3 1 0 0 1 1 1 0 PAP2 superfamily PEX-1N PF09262.6 EMD66728.1 - 0.035 14.1 0.1 0.085 12.9 0.1 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal IncA PF04156.9 EMD66728.1 - 8.4 5.9 7.8 1 8.9 0.9 2.1 1 1 1 2 2 2 0 IncA protein HET PF06985.6 EMD66729.1 - 5.6e-20 71.9 7.8 7.4e-17 61.8 1.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) KRE9 PF05390.6 EMD66729.1 - 0.053 13.8 0.3 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 AMP-binding PF00501.23 EMD66731.1 - 5e-89 298.5 0.0 7.2e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RabGAP-TBC PF00566.13 EMD66731.1 - 2.6e-47 161.0 0.1 4.3e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AMP-binding_C PF13193.1 EMD66731.1 - 9.2e-17 61.7 0.5 2.7e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.1 EMD66731.1 - 1.4e-05 24.5 0.8 0.019 14.8 0.1 4.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EMD66731.1 - 0.00012 22.1 1.0 0.0021 18.1 0.5 3.2 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 EMD66731.1 - 0.0028 16.9 0.4 0.048 13.0 0.2 2.8 2 0 0 2 2 2 1 EF hand DUF1967 PF09269.6 EMD66731.1 - 0.012 15.2 0.1 0.79 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) EF-hand_1 PF00036.27 EMD66731.1 - 0.37 10.2 10.8 0.14 11.4 0.3 4.6 5 0 0 5 5 5 0 EF hand adh_short_C2 PF13561.1 EMD66732.1 - 9.1e-28 97.6 0.0 1.2e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD66732.1 - 1.4e-24 86.8 0.5 2.1e-24 86.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD66732.1 - 6.4e-13 48.7 0.3 1.1e-12 47.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD66732.1 - 0.01 15.2 0.2 0.031 13.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMD66732.1 - 0.028 14.0 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Exo_endo_phos PF03372.18 EMD66733.1 - 2.6e-17 63.6 0.1 3.4e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C41 PF05417.6 EMD66734.1 - 0.039 13.5 0.0 0.041 13.4 0.0 1.0 1 0 0 1 1 1 0 Hepatitis E cysteine protease adh_short PF00106.20 EMD66737.1 - 4.6e-24 85.2 0.1 1e-23 84.1 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD66737.1 - 4.3e-07 29.7 0.1 9.9e-07 28.5 0.1 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD66737.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Multi-haem_cyto PF13447.1 EMD66739.1 - 0.048 12.7 1.7 0.046 12.7 1.2 1.1 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH DUF1924 PF09086.6 EMD66739.1 - 0.1 12.6 0.5 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Mu-like_Com PF10122.4 EMD66739.1 - 0.27 10.3 4.8 0.55 9.3 3.3 1.5 1 1 0 1 1 1 0 Mu-like prophage protein Com Lipase_3 PF01764.20 EMD66740.1 - 3.2e-06 26.8 0.0 6.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMD66740.1 - 0.012 15.4 0.0 0.061 13.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EMD66740.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF3487 PF11990.3 EMD66741.1 - 0.0045 16.3 2.2 0.95 8.8 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3487) SUR7 PF06687.7 EMD66741.1 - 3.9 6.9 10.7 10 5.6 5.0 2.1 2 0 0 2 2 2 0 SUR7/PalI family Tic20 PF09685.5 EMD66741.1 - 6.9 6.6 11.8 1.3 9.0 3.3 2.4 2 1 0 2 2 2 0 Tic20-like protein Ank_2 PF12796.2 EMD66742.1 - 2.5e-26 91.8 9.8 5e-13 49.2 0.6 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMD66742.1 - 3.5e-19 67.5 19.6 0.00013 21.6 0.3 6.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EMD66742.1 - 4.9e-17 60.3 13.6 0.0063 16.6 0.1 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EMD66742.1 - 1.5e-14 54.0 6.2 0.00047 20.5 0.2 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD66742.1 - 6.4e-12 45.2 10.8 0.0082 16.3 0.1 5.5 2 1 5 7 7 7 3 Ankyrin repeats (many copies) PPP4R2 PF09184.6 EMD66742.1 - 0.43 10.0 10.4 2 7.9 0.0 2.2 2 0 0 2 2 2 0 PPP4R2 Sigma70_ner PF04546.8 EMD66742.1 - 1.9 8.0 7.5 3.5 7.1 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EMD66742.1 - 3 5.6 8.4 4 5.2 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMD66742.1 - 9 5.4 6.5 15 4.7 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein Lipase_GDSL_2 PF13472.1 EMD66743.1 - 1.7e-16 60.8 1.1 2.1e-16 60.5 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD66743.1 - 1.6e-13 51.0 0.6 2e-13 50.7 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4149 PF13664.1 EMD66744.1 - 2.5e-19 69.2 1.3 2.5e-19 69.2 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Fungal_trans PF04082.13 EMD66745.1 - 3e-10 39.4 0.1 6.6e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66745.1 - 0.001 18.9 11.1 0.0018 18.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2502 PF10697.4 EMD66746.1 - 0.012 15.7 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Fungal_trans PF04082.13 EMD66748.1 - 2.9e-14 52.5 0.0 5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66748.1 - 1.1e-08 34.8 7.9 2.2e-08 33.8 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IDO PF01231.13 EMD66749.1 - 1.7e-148 494.5 0.0 2.1e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 EMD66750.1 - 1.6e-08 33.7 0.0 2.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMD66750.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PHD PF00628.24 EMD66752.1 - 4.8e-10 38.9 1.3 1.1e-09 37.8 0.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMD66752.1 - 0.059 12.6 2.3 0.098 11.9 1.6 1.4 1 0 0 1 1 1 0 PHD-finger Gin PF10764.4 EMD66752.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin PNTB PF02233.11 EMD66753.1 - 1.9e-169 564.2 25.6 1.9e-169 564.2 17.8 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EMD66753.1 - 1.4e-53 180.8 1.0 2.5e-53 180.1 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EMD66753.1 - 1.4e-45 154.5 0.2 3.4e-45 153.3 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EMD66753.1 - 1.9e-31 108.0 3.1 1.9e-31 108.0 2.1 4.7 4 2 2 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EMD66753.1 - 0.0021 17.2 0.4 0.96 8.5 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EMD66753.1 - 0.0047 16.4 0.3 0.013 15.0 0.2 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 EMD66753.1 - 0.0072 16.0 0.7 0.062 13.0 0.3 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fumerase PF05681.9 EMD66753.1 - 0.016 14.2 0.1 0.03 13.3 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Pyr_redox_2 PF07992.9 EMD66753.1 - 0.1 12.4 2.4 0.11 12.3 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD66753.1 - 8.4 6.5 8.3 0.93 9.5 1.5 2.8 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain PAN_4 PF14295.1 EMD66754.1 - 0.017 14.8 1.8 0.017 14.8 1.2 2.5 2 0 0 2 2 2 0 PAN domain DUF4360 PF14273.1 EMD66755.1 - 6.6e-72 241.0 2.7 7.8e-72 240.7 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Velvet PF11754.3 EMD66756.1 - 1.9e-05 24.3 0.1 9e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 Velvet factor tRNA-synt_1d PF00750.14 EMD66757.1 - 1.3e-79 267.6 10.6 7.3e-44 150.0 5.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EMD66757.1 - 1.1e-28 99.5 0.5 1.1e-28 99.5 0.3 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EMD66757.1 - 7.4e-06 26.4 0.0 7.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DivIC PF04977.10 EMD66757.1 - 0.0025 17.2 5.7 0.0073 15.7 2.8 2.3 2 0 0 2 2 2 1 Septum formation initiator CAF-1_p150 PF11600.3 EMD66759.1 - 0.0047 16.3 1.4 0.0047 16.3 1.0 1.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RTA1 PF04479.8 EMD66760.1 - 3.1e-50 170.7 1.1 5.2e-50 170.0 0.8 1.4 1 0 0 1 1 1 1 RTA1 like protein COX7B PF05392.6 EMD66760.1 - 0.044 13.3 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB DDOST_48kD PF03345.9 EMD66762.1 - 9.4e-158 525.1 0.0 1.1e-157 525.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GST_N_2 PF13409.1 EMD66763.1 - 5.7e-15 55.0 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD66763.1 - 1.2e-11 44.3 0.0 4.4e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD66763.1 - 0.00027 21.3 0.0 0.00048 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD66763.1 - 0.0028 17.8 0.0 0.038 14.2 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD66763.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cation_efflux PF01545.16 EMD66764.1 - 5.7e-73 245.4 7.5 6.5e-73 245.2 5.2 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 EMD66764.1 - 3.8e-05 22.7 1.5 3.8e-05 22.7 1.0 2.2 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component zf-met2 PF12907.2 EMD66765.1 - 7.2e-13 48.2 3.3 1.1e-12 47.7 2.3 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EMD66765.1 - 0.0054 17.4 11.4 0.026 15.2 7.9 2.0 1 1 0 1 1 1 1 4F5 protein family YvbH_ext PF11724.3 EMD66765.1 - 0.021 14.5 0.1 0.026 14.1 0.1 1.3 1 1 0 1 1 1 0 YvbH-like oligomerisation region DUF3721 PF12518.3 EMD66765.1 - 0.22 11.1 1.4 0.37 10.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function zf-RING_2 PF13639.1 EMD66766.1 - 0.014 15.1 4.3 0.014 15.1 3.0 2.2 2 0 0 2 2 2 0 Ring finger domain UPF0547 PF10571.4 EMD66766.1 - 0.051 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-rbx1 PF12678.2 EMD66766.1 - 0.062 13.4 1.4 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Sgf11 PF08209.6 EMD66766.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_2 PF13923.1 EMD66766.1 - 2.7 8.1 9.4 0.33 11.0 2.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.2 EMD66769.1 - 0.085 12.6 0.3 0.085 12.6 0.2 2.0 2 0 0 2 2 2 0 F-box-like PRANC PF09372.5 EMD66769.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain TEP1_N PF05386.6 EMD66769.1 - 0.57 9.6 2.2 1.1 8.7 0.1 2.5 3 0 0 3 3 3 0 TEP1 N-terminal domain PC4 PF02229.11 EMD66771.1 - 3e-21 74.4 0.0 5e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RRM_1 PF00076.17 EMD66772.1 - 6.3e-17 60.9 0.2 3.9e-16 58.4 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66772.1 - 4.9e-12 45.6 0.0 9.1e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66772.1 - 2.6e-07 30.3 0.0 6.4e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.14 EMD66772.1 - 1.8 8.2 19.7 2.5 7.7 13.7 1.2 1 0 0 1 1 1 0 SPX domain DLIC PF05783.6 EMD66773.1 - 5.1e-33 114.4 2.6 3.4e-31 108.4 0.0 3.6 2 2 0 3 3 3 2 Dynein light intermediate chain (DLIC) zf-Apc11 PF12861.2 EMD66774.1 - 0.27 11.0 2.3 4.3 7.2 0.3 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYDLN_acid PF09538.5 EMD66774.1 - 0.3 11.7 1.8 3.9 8.1 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) 4HBT PF03061.17 EMD66776.1 - 3.5e-12 46.2 0.1 4.8e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily tRNA_anti-codon PF01336.20 EMD66776.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PXA PF02194.10 EMD66777.1 - 1.2e-33 116.2 0.1 1.2e-33 116.2 0.0 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EMD66777.1 - 1.1e-21 76.9 0.1 1e-20 73.8 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EMD66777.1 - 3.6e-08 33.1 0.0 1.4e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 PX domain Tup_N PF08581.5 EMD66778.1 - 0.016 15.3 0.1 0.016 15.3 0.1 11.4 9 3 2 11 11 11 0 Tup N-terminal PCI PF01399.22 EMD66779.1 - 4.7e-21 75.0 0.8 1.2e-20 73.7 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 EMD66779.1 - 6.1e-05 22.5 2.9 1.3 9.0 0.1 5.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD66779.1 - 0.0015 19.0 4.7 0.94 10.2 0.0 5.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD66779.1 - 0.0035 17.2 11.9 2.5 8.1 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 EMD66779.1 - 0.0039 16.6 0.2 0.0083 15.5 0.2 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_16 PF13432.1 EMD66779.1 - 0.0073 16.9 10.5 0.27 11.9 0.1 4.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD66779.1 - 0.012 15.9 8.4 0.14 12.4 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPPII_N PF12583.3 EMD66779.1 - 0.032 14.3 0.1 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal TPR_1 PF00515.23 EMD66779.1 - 0.052 13.1 6.8 7.9 6.2 0.0 5.4 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF627 PF04781.7 EMD66779.1 - 0.084 12.5 1.7 1.2 8.7 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF627) TPR_11 PF13414.1 EMD66779.1 - 0.15 11.7 9.9 0.55 9.9 0.1 4.0 4 1 1 5 5 5 0 TPR repeat Prefoldin_2 PF01920.15 EMD66779.1 - 0.26 11.0 6.0 0.076 12.7 0.7 2.7 3 0 0 3 3 3 0 Prefoldin subunit TPR_6 PF13174.1 EMD66779.1 - 0.47 11.0 0.0 0.47 11.0 0.0 5.5 7 1 0 7 7 6 0 Tetratricopeptide repeat Prefoldin PF02996.12 EMD66779.1 - 0.57 9.8 4.5 0.8 9.3 0.1 3.0 3 0 0 3 3 3 0 Prefoldin subunit PAPA-1 PF04795.7 EMD66780.1 - 0.0046 17.6 1.9 0.0079 16.8 1.3 1.3 1 0 0 1 1 1 1 PAPA-1-like conserved region ERF PF04404.7 EMD66780.1 - 0.02 14.4 0.7 0.033 13.7 0.5 1.3 1 0 0 1 1 1 0 ERF superfamily zf-LITAF-like PF10601.4 EMD66780.1 - 0.021 14.6 0.9 0.032 14.0 0.6 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Anoctamin PF04547.7 EMD66780.1 - 0.081 11.5 0.2 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel UPF0233 PF06781.7 EMD66780.1 - 0.17 11.5 0.5 2.7 7.7 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) Suf PF05843.9 EMD66780.1 - 0.32 10.6 4.7 0.35 10.5 3.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3357 PF11837.3 EMD66780.1 - 0.35 10.7 3.5 1 9.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) PAT1 PF09770.4 EMD66780.1 - 0.6 8.2 11.5 0.71 8.0 7.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3675 PF12428.3 EMD66780.1 - 1.5 9.0 5.8 5.7 7.2 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) C1_4 PF07975.7 EMD66780.1 - 3.2 7.8 7.4 0.21 11.6 1.4 1.8 2 0 0 2 2 2 0 TFIIH C1-like domain DDE_1 PF03184.14 EMD66781.1 - 1.7e-12 46.9 0.0 1.9e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PUA_2 PF14306.1 EMD66782.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 PUA-like domain DUF2968 PF11180.3 EMD66782.1 - 1.7 7.9 11.0 2.5 7.4 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3328 PF11807.3 EMD66783.1 - 6.8e-12 45.5 3.8 1e-11 44.9 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Mito_carr PF00153.22 EMD66784.1 - 2.5e-47 158.5 0.2 5.9e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RRF PF01765.14 EMD66784.1 - 0.061 12.7 0.8 0.1 12.0 0.6 1.4 1 0 0 1 1 1 0 Ribosome recycling factor DUF883 PF05957.8 EMD66784.1 - 0.097 13.0 4.4 0.42 11.0 2.2 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Apo-CIII PF05778.7 EMD66784.1 - 0.14 11.5 1.0 0.46 9.8 0.2 2.2 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) HSP9_HSP12 PF04119.7 EMD66784.1 - 9.4 6.4 8.2 0.54 10.3 1.4 2.2 2 0 0 2 2 2 0 Heat shock protein 9/12 NUDE_C PF04880.8 EMD66785.1 - 2.8e-14 53.8 18.6 2.8e-14 53.8 12.9 4.3 2 2 1 3 3 3 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EMD66785.1 - 0.59 10.4 38.4 0.026 14.7 4.9 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF904) Filament PF00038.16 EMD66785.1 - 1.2 8.5 34.8 3.8 6.8 10.7 3.0 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.2 EMD66785.1 - 1.7 8.4 40.9 3.2 7.6 3.6 3.7 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.3 EMD66785.1 - 2.9 5.1 28.6 4 4.6 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EMD66785.1 - 3.6 7.4 39.8 5.5 6.8 8.8 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EMD66785.1 - 7.4 6.6 24.3 0.47 10.4 9.3 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EMD66785.1 - 8 6.0 38.4 10 5.6 15.4 2.4 1 1 1 2 2 2 0 IncA protein ACC_central PF08326.7 EMD66788.1 - 2.6e-258 858.8 0.0 3.1e-258 858.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EMD66788.1 - 2e-177 590.5 0.0 3.4e-177 589.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EMD66788.1 - 5.6e-53 179.3 0.0 1.1e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMD66788.1 - 2.3e-24 85.5 0.1 5e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMD66788.1 - 7.6e-22 77.3 0.0 1.3e-20 73.3 0.0 3.1 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EMD66788.1 - 4.3e-16 58.3 0.0 1.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMD66788.1 - 5.2e-09 36.1 0.0 1.4e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD66788.1 - 5.4e-09 35.2 0.0 9.9e-07 27.7 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMD66788.1 - 3e-05 23.5 0.0 7.2e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EMD66788.1 - 0.0013 18.6 0.0 0.006 16.4 0.0 2.2 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMD66788.1 - 0.028 13.9 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ABM PF03992.11 EMD66789.1 - 3e-05 23.9 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF482 PF04339.7 EMD66789.1 - 0.0049 15.7 0.1 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF482 COX7a PF02238.10 EMD66791.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa DUF1682 PF07946.9 EMD66792.1 - 5.6e-103 344.1 0.4 6.4e-103 343.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tom37_C PF11801.3 EMD66792.1 - 0.079 12.8 2.7 0.16 11.8 1.9 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain eIF-5a PF01287.15 EMD66794.1 - 4.2e-05 23.4 0.1 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CH PF00307.26 EMD66795.1 - 6.4e-66 219.1 0.1 6.6e-20 71.1 0.3 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EMD66795.1 - 2.3e-07 30.8 0.7 2e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMD66795.1 - 0.00011 21.2 1.1 0.052 12.8 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EMD66795.1 - 0.00022 20.8 0.2 0.005 16.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain CAMSAP_CH PF11971.3 EMD66795.1 - 0.00029 20.4 0.0 0.97 9.1 0.0 3.6 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_5 PF13202.1 EMD66795.1 - 0.15 11.4 2.6 0.33 10.3 0.2 2.7 2 0 0 2 2 2 0 EF hand KilA-N PF04383.8 EMD66796.1 - 3.6e-05 23.3 0.0 0.00047 19.7 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Fer4_3 PF12798.2 EMD66798.1 - 0.86 10.3 3.8 1 10.0 0.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain CbbQ_C PF08406.5 EMD66799.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal FAD_binding_4 PF01565.18 EMD66802.1 - 1e-22 80.1 1.4 2.6e-22 78.8 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD66802.1 - 1.7e-06 27.8 0.3 3.4e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Secretin PF00263.16 EMD66802.1 - 0.1 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein HAD_2 PF13419.1 EMD66803.1 - 1.1e-22 81.1 0.0 2.1e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD66803.1 - 1.4e-10 41.9 0.1 2.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD66803.1 - 1.3e-06 28.0 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMD66803.1 - 3e-06 27.5 0.0 4.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMD66803.1 - 0.011 15.6 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EMD66803.1 - 0.1 11.9 0.0 14 4.9 0.0 2.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) WD40 PF00400.27 EMD66804.1 - 2.5e-39 131.7 5.9 2.1e-10 40.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EMD66804.1 - 4.5e-29 100.3 15.1 1e-28 99.1 10.5 1.6 1 0 0 1 1 1 1 Sof1-like domain DUF3312 PF11768.3 EMD66804.1 - 0.00017 19.9 0.0 0.34 9.0 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3312) eIF2A PF08662.6 EMD66804.1 - 0.0011 18.6 0.6 0.11 12.2 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EMD66804.1 - 0.0022 17.7 0.1 8.6 6.1 0.0 3.6 2 2 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ribosomal_L27e PF01777.13 EMD66805.1 - 1.2e-36 124.6 7.0 1.5e-36 124.3 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EMD66805.1 - 1.3e-05 24.7 1.0 2.1e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 KOW motif DUF1922 PF09082.5 EMD66805.1 - 0.091 12.8 0.7 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) RNA_pol_Rpb1_5 PF04998.12 EMD66807.1 - 1.1e-87 293.8 0.6 1.1e-87 293.8 0.4 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMD66807.1 - 8.4e-63 211.2 2.0 8.9e-63 211.1 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMD66807.1 - 1.3e-32 112.6 0.0 1.3e-31 109.4 0.0 2.6 3 1 1 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EMD66807.1 - 1.1e-26 93.8 12.0 7.5e-23 81.3 0.0 3.4 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EMD66807.1 - 5.9e-19 67.7 0.8 2.4e-18 65.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 EMD66808.1 - 1.9e-62 210.5 1.6 3.2e-62 209.8 1.1 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EMD66808.1 - 2.8e-35 120.7 1.1 3.8e-35 120.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.7 EMD66808.1 - 0.0092 15.6 0.0 3.8 7.2 0.0 2.8 2 0 0 2 2 2 2 Sensors of blue-light using FAD Rotamase_2 PF13145.1 EMD66808.1 - 4 8.1 12.6 1.2 9.8 1.5 3.7 4 0 0 4 4 4 0 PPIC-type PPIASE domain muHD PF10291.4 EMD66809.1 - 2.9e-70 236.3 0.0 4.5e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EMD66809.1 - 4.3e-12 46.0 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Syntaxin PF00804.20 EMD66809.1 - 0.16 12.1 6.0 0.36 10.9 3.1 2.2 1 1 1 2 2 2 0 Syntaxin Mo25 PF08569.6 EMD66810.1 - 1.4e-108 362.9 0.1 3.3e-107 358.4 0.1 2.0 1 1 0 1 1 1 1 Mo25-like Pkinase PF00069.20 EMD66810.1 - 1e-35 123.1 0.0 2.9e-35 121.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66810.1 - 2.8e-14 52.8 0.0 6.2e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD66810.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF544 PF04424.8 EMD66810.1 - 0.027 14.2 0.1 0.095 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF544) RepA_N PF06970.6 EMD66810.1 - 0.091 12.5 0.5 0.36 10.6 0.3 2.0 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus TPT PF03151.11 EMD66811.1 - 5.1e-33 113.8 16.3 7.4e-33 113.3 5.9 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EMD66811.1 - 2.3e-05 24.4 26.3 0.021 14.8 4.5 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EMD66811.1 - 0.0012 17.8 17.3 0.0012 17.8 12.0 1.9 1 1 1 2 2 2 1 UAA transporter family CDC45 PF02724.9 EMD66811.1 - 0.031 12.3 3.5 0.043 11.8 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EMD66811.1 - 0.38 8.7 1.8 0.53 8.3 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3661 PF12400.3 EMD66812.1 - 1.7e-44 150.9 1.9 2.7e-44 150.3 1.3 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein FKBP_C PF00254.23 EMD66812.1 - 4.4e-29 100.3 0.0 6.8e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CoA_trans PF01144.18 EMD66813.1 - 1.8e-101 337.8 0.9 3e-60 203.1 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase HATPase_c PF02518.21 EMD66814.1 - 3.9e-26 90.9 0.1 7.1e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD66814.1 - 8e-19 67.4 0.1 2.1e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EMD66814.1 - 1e-16 60.7 1.9 1e-08 35.1 0.4 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.19 EMD66814.1 - 1.5e-16 60.4 0.0 5.5e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.19 EMD66814.1 - 2.9e-13 49.5 0.0 2.4e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EMD66814.1 - 2.2e-12 47.2 0.0 1.9e-08 34.5 0.0 3.1 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMD66814.1 - 2.2e-06 27.6 0.0 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EMD66814.1 - 0.0049 16.6 0.0 0.084 12.7 0.0 2.5 2 0 0 2 2 2 1 PAS domain Cytochrom_B561 PF03188.11 EMD66815.1 - 5.9e-17 61.7 4.1 5.9e-17 61.7 2.9 1.6 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.15 EMD66815.1 - 0.35 10.2 12.8 0.38 10.1 7.4 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF3681 PF12442.3 EMD66815.1 - 0.84 9.8 7.8 0.14 12.3 1.8 2.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3681) DUF3040 PF11239.3 EMD66815.1 - 1.2 9.2 4.8 6.4 6.8 0.8 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) MerC PF03203.9 EMD66815.1 - 8.9 6.7 11.7 0.48 10.8 2.2 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein BTB PF00651.26 EMD66816.1 - 6.3e-20 71.2 0.1 2.5e-09 37.1 0.0 3.2 4 0 0 4 4 4 2 BTB/POZ domain Glyco_hydro_16 PF00722.16 EMD66817.1 - 4.6e-06 26.0 2.8 7.4e-06 25.3 1.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Epimerase PF01370.16 EMD66818.1 - 1.3e-31 109.9 0.0 1.8e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMD66818.1 - 4e-14 52.3 0.0 7.7e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EMD66818.1 - 3.8e-09 35.8 0.0 1.1e-07 31.0 0.0 2.5 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EMD66818.1 - 2e-07 30.2 0.0 2.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EMD66818.1 - 9.8e-06 24.4 0.0 4.4e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD66818.1 - 1e-05 25.5 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD66818.1 - 2.4e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 EMD66818.1 - 0.0025 17.2 0.0 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EMD66818.1 - 0.0032 17.4 0.0 0.065 13.2 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding DAO PF01266.19 EMD66818.1 - 0.0034 16.3 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EMD66818.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMD66818.1 - 0.053 12.3 0.0 0.56 9.0 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain FAD_binding_3 PF01494.14 EMD66818.1 - 0.094 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Glyco_tranf_2_3 PF13641.1 EMD66819.1 - 4.9e-08 33.0 0.1 1.2e-07 31.7 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD66819.1 - 5.8e-06 26.1 1.7 8.6e-06 25.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMD66819.1 - 2e-05 24.3 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD66819.1 - 7.3e-05 22.1 0.1 0.00023 20.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Acetyltransf_3 PF13302.1 EMD66820.1 - 9.2e-20 71.2 0.0 1.7e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD66820.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMD66820.1 - 4e-08 33.3 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMD66820.1 - 7.2e-07 29.2 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD66820.1 - 0.0008 19.1 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.11 EMD66822.1 - 1.1e-26 93.3 27.6 1.1e-26 93.3 19.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.9 EMD66823.1 - 6.5e-21 73.6 6.2 3.1e-20 71.4 0.7 2.7 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EMD66823.1 - 0.48 10.3 5.7 0.064 13.1 0.5 2.2 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ABC2_membrane_5 PF13346.1 EMD66823.1 - 1 8.6 9.2 0.54 9.5 3.5 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EMD66825.1 - 0.042 13.1 0.7 0.067 12.4 0.5 1.3 1 0 0 1 1 1 0 Tetraspanin family Mif2_N PF15624.1 EMD66826.1 - 0.027 15.0 0.5 0.04 14.5 0.3 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal KAR9 PF08580.5 EMD66826.1 - 3.6 5.7 6.6 4.4 5.4 4.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 F-box PF00646.28 EMD66828.1 - 0.0059 16.2 1.0 0.016 14.8 0.2 2.1 2 0 0 2 2 2 1 F-box domain Bys1 PF04681.7 EMD66829.1 - 1.1e-10 41.4 0.2 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein AFP PF02420.10 EMD66829.1 - 0.069 13.3 4.4 4.1 7.8 0.1 3.6 3 0 0 3 3 3 0 Insect antifreeze protein repeat SLAC1 PF03595.12 EMD66830.1 - 4.9e-64 216.0 32.5 5.5e-64 215.8 22.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF202 PF02656.10 EMD66830.1 - 0.73 10.0 13.1 4.6 7.5 0.2 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Adeno_E3 PF06040.6 EMD66830.1 - 2.1 8.3 8.3 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Adenovirus E3 protein DUF3328 PF11807.3 EMD66831.1 - 0.00023 20.9 7.3 0.0067 16.1 5.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EMD66831.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Acetyltransf_1 PF00583.19 EMD66832.1 - 7.6e-09 35.4 0.4 2.7e-08 33.7 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD66832.1 - 2.1e-08 34.2 0.0 3.7e-07 30.2 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD66832.1 - 6.4e-06 26.2 0.2 0.00049 20.1 0.0 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD66832.1 - 3.7e-05 23.3 0.0 0.001 18.7 0.0 2.1 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EMD66832.1 - 0.0007 19.4 0.0 0.0018 18.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD66832.1 - 0.0075 16.1 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase His_biosynth PF00977.16 EMD66832.1 - 0.078 12.2 0.1 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Zn_clus PF00172.13 EMD66833.1 - 0.00044 20.0 8.4 0.00044 20.0 5.8 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EMD66834.1 - 2.7e-08 33.3 0.0 4.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DLH PF01738.13 EMD66835.1 - 0.01 15.1 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3328 PF11807.3 EMD66836.1 - 0.00067 19.4 1.6 0.0061 16.2 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) MFS_2 PF13347.1 EMD66837.1 - 2.2e-09 36.2 16.6 5.5e-09 34.9 11.2 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein Cupredoxin_1 PF13473.1 EMD66838.1 - 1.4e-05 24.8 25.9 0.082 12.8 2.3 5.0 1 1 4 5 5 5 5 Cupredoxin-like domain AMP-binding PF00501.23 EMD66839.1 - 0 1112.6 4.6 1.2e-87 294.0 0.4 4.7 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 EMD66839.1 - 0 1248.6 3.7 2.4e-50 171.1 0.0 9.7 9 1 0 9 9 9 9 Condensation domain PP-binding PF00550.20 EMD66839.1 - 8.4e-70 230.9 10.6 3.5e-12 46.4 0.1 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site Transferase PF02458.10 EMD66839.1 - 2.5e-09 36.0 0.0 0.00085 17.8 0.0 4.5 5 0 0 5 5 5 3 Transferase family AATase PF07247.7 EMD66839.1 - 0.011 14.3 0.7 23 3.3 0.0 5.2 6 0 0 6 6 6 0 Alcohol acetyltransferase ABC_tran PF00005.22 EMD66840.1 - 1.7e-43 148.2 0.0 2e-23 83.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMD66840.1 - 3.3e-40 138.2 30.6 7.7e-29 100.9 8.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMD66840.1 - 5.3e-11 42.1 2.3 0.0013 17.9 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD66840.1 - 7.2e-10 39.3 0.3 0.015 15.2 0.0 3.6 2 1 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EMD66840.1 - 2.5e-09 37.3 0.2 0.00025 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD66840.1 - 8.6e-08 31.6 1.8 0.0054 16.2 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD66840.1 - 1.5e-06 27.7 0.1 0.043 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD66840.1 - 7.4e-06 25.2 0.2 0.038 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMD66840.1 - 1.6e-05 25.0 1.6 0.078 13.1 0.0 3.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EMD66840.1 - 2.5e-05 24.7 0.2 0.11 13.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EMD66840.1 - 2.9e-05 23.9 0.0 0.052 13.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EMD66840.1 - 8.5e-05 22.3 0.1 0.0087 15.7 0.0 3.0 4 0 0 4 4 2 1 Archaeal ATPase AAA_23 PF13476.1 EMD66840.1 - 0.00011 22.6 0.1 0.29 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EMD66840.1 - 0.00058 19.5 3.7 0.53 9.9 0.1 2.8 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EMD66840.1 - 0.00094 19.3 0.2 0.053 13.7 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD66840.1 - 0.0013 19.5 0.1 1.7 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD66840.1 - 0.0015 18.4 0.1 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EMD66840.1 - 0.0027 17.5 2.2 0.61 9.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 EMD66840.1 - 0.003 16.4 0.1 0.32 9.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EMD66840.1 - 0.0053 16.3 0.5 1.9 7.9 0.0 3.0 4 0 0 4 4 2 1 Viral (Superfamily 1) RNA helicase AAA_PrkA PF08298.6 EMD66840.1 - 0.0066 15.1 0.2 1.7 7.2 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain AAA_14 PF13173.1 EMD66840.1 - 0.0081 16.0 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMD66840.1 - 0.0091 16.1 0.1 4.4 7.5 0.0 3.2 2 1 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.10 EMD66840.1 - 0.0097 14.5 0.1 0.23 10.0 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein NACHT PF05729.7 EMD66840.1 - 0.011 15.4 0.6 2.2 7.9 0.0 2.8 3 0 0 3 3 2 0 NACHT domain DUF815 PF05673.8 EMD66840.1 - 0.011 14.6 0.1 4.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EMD66840.1 - 0.012 15.1 1.3 2.9 7.3 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EMD66840.1 - 0.012 15.0 6.6 0.53 9.6 0.5 2.7 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMD66840.1 - 0.022 14.2 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EMD66840.1 - 0.024 14.9 0.1 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMD66840.1 - 0.027 14.4 1.4 1.1 9.2 0.0 2.9 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EMD66840.1 - 0.032 13.0 0.2 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 EMD66840.1 - 0.034 13.6 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 EMD66840.1 - 0.041 13.3 0.7 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EMD66840.1 - 0.061 12.4 1.1 6.2 5.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EMD66840.1 - 0.097 12.4 1.7 1.7 8.4 0.1 2.9 3 0 0 3 3 2 0 Part of AAA domain ABC_ATPase PF09818.4 EMD66840.1 - 0.1 11.1 0.1 0.1 11.1 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 EMD66840.1 - 0.12 12.0 1.1 17 5.1 0.2 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EMD66840.1 - 0.17 11.3 4.2 1.3 8.4 0.2 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EMD66840.1 - 0.21 11.3 2.4 0.14 11.9 0.2 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_30 PF13604.1 EMD66840.1 - 0.24 10.9 0.3 11 5.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 EMD66840.1 - 0.26 10.5 0.5 0.88 8.8 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 EMD66840.1 - 0.26 10.7 1.0 16 4.9 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EMD66840.1 - 0.28 10.1 0.5 17 4.2 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 EMD66840.1 - 0.45 10.0 0.6 23 4.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMD66840.1 - 0.46 10.1 1.4 12 5.6 0.1 2.8 3 0 0 3 3 2 0 NTPase DUF3671 PF12420.3 EMD66840.1 - 8.8 6.3 13.4 0.54 10.2 0.1 3.8 4 0 0 4 4 3 0 Protein of unknown function MFS_1 PF07690.11 EMD66842.1 - 1.5e-20 73.2 33.3 1.5e-20 73.2 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Dicistro_VP4 PF11492.3 EMD66843.1 - 0.41 10.7 2.9 0.24 11.4 0.3 1.8 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 HET PF06985.6 EMD66844.1 - 3.5e-29 101.7 0.0 5.4e-29 101.1 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSH-S_ATP PF02955.11 EMD66845.1 - 0.0022 17.1 0.0 0.0057 15.8 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain G-7-MTase PF12803.2 EMD66845.1 - 0.015 14.5 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SGS PF05002.10 EMD66845.1 - 0.055 13.2 0.1 0.19 11.4 0.0 1.8 1 1 1 2 2 2 0 SGS domain WSC PF01822.14 EMD66846.1 - 1.8e-39 133.5 31.4 1.5e-21 76.0 8.7 3.0 3 0 0 3 3 3 2 WSC domain Trypan_PARP PF05887.6 EMD66846.1 - 0.44 10.3 11.1 0.78 9.5 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 EMD66847.1 - 7.2e-17 61.3 0.0 1.8e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66847.1 - 3.5e-07 29.5 0.0 6.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EMD66848.1 - 1.1e-25 90.2 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 EMD66848.1 - 8.8e-21 74.5 0.0 1.9e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 EMD66848.1 - 1.5e-16 60.2 0.0 2.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.1 EMD66849.1 - 5.5e-45 153.7 0.0 1.1e-44 152.7 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF3054 PF11255.3 EMD66850.1 - 0.097 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) zf-TAZ PF02135.11 EMD66850.1 - 0.29 11.1 3.2 0.51 10.3 2.2 1.4 1 0 0 1 1 1 0 TAZ zinc finger DAO PF01266.19 EMD66851.1 - 1.2e-09 37.5 0.2 1.4e-09 37.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD66851.1 - 0.044 14.1 0.1 0.044 14.1 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 EMD66851.1 - 0.053 13.3 0.1 0.44 10.3 0.1 2.0 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SIC PF03482.8 EMD66851.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 sic protein Peptidase_S10 PF00450.17 EMD66855.1 - 1.9e-84 284.2 0.1 2.6e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase dCMP_cyt_deam_1 PF00383.17 EMD66856.1 - 5.8e-25 86.8 2.1 8.4e-25 86.3 1.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CoaE PF01121.15 EMD66856.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.1 EMD66856.1 - 0.15 12.8 0.1 0.44 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain ThiF PF00899.16 EMD66857.1 - 1.9e-29 102.2 0.0 4.6e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EMD66857.1 - 0.0052 16.8 0.0 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Mg_trans_NIPA PF05653.9 EMD66858.1 - 3.6e-89 298.6 22.7 5.2e-89 298.1 15.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMD66858.1 - 5e-07 29.9 0.6 5e-07 29.9 0.4 3.2 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD66858.1 - 0.00041 20.3 4.5 0.00041 20.3 3.1 3.5 3 1 1 4 4 4 1 EamA-like transporter family DUF1237 PF06824.6 EMD66859.1 - 2.4e-134 448.1 0.1 3e-132 441.2 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) COG4 PF08318.7 EMD66859.1 - 1e-93 313.7 0.0 1.5e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein NMO PF03060.10 EMD66860.1 - 6.1e-38 130.7 8.7 1.2e-31 110.0 2.6 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EMD66860.1 - 3.2e-06 26.2 4.7 5.9e-06 25.3 3.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMD66860.1 - 0.00011 21.2 1.9 0.0002 20.4 1.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMD66860.1 - 0.0016 17.3 1.7 0.014 14.3 1.6 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Abhydro_lipase PF04083.11 EMD66862.1 - 8e-22 76.3 0.1 1.6e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMD66862.1 - 3.1e-14 53.0 0.0 7.6e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD66862.1 - 4e-06 26.8 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMD66862.1 - 8.5e-05 22.0 0.6 0.034 13.6 0.0 2.7 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Pet191_N PF10203.4 EMD66863.1 - 3.7e-28 97.3 2.1 4.7e-28 97.0 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EMD66863.1 - 0.087 12.6 1.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Fungal_trans_2 PF11951.3 EMD66864.1 - 7.9e-19 67.4 0.8 1.2e-18 66.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66864.1 - 0.0037 17.1 12.5 0.0037 17.1 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EMD66865.1 - 5e-07 29.4 3.1 3.4e-06 26.7 2.2 2.0 1 1 0 1 1 1 1 RTA1 like protein PAN_4 PF14295.1 EMD66866.1 - 5.3e-17 61.2 4.4 9.3e-09 34.8 0.1 3.0 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.7 EMD66866.1 - 9.9e-05 21.8 1.6 0.34 10.5 0.2 2.7 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.6 EMD66866.1 - 0.00029 20.5 0.9 0.021 14.6 0.1 2.6 2 0 0 2 2 2 1 PAN-like domain SUKH-4 PF14435.1 EMD66869.1 - 0.027 14.1 4.2 0.054 13.2 2.9 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein F-box-like_2 PF13013.1 EMD66869.1 - 0.078 12.7 0.5 0.78 9.4 0.0 2.8 3 0 0 3 3 3 0 F-box-like domain adh_short PF00106.20 EMD66871.1 - 1.1e-13 51.5 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD66871.1 - 0.00012 21.7 0.0 0.00051 19.7 0.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD66871.1 - 0.0029 17.4 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD66871.1 - 0.0038 16.7 0.0 0.0073 15.7 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EMD66874.1 - 8.4e-48 163.0 0.0 9.7e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Caps_synth PF05704.7 EMD66874.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Lge1 PF11488.3 EMD66874.1 - 0.12 12.5 0.3 0.35 11.0 0.2 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DEAD PF00270.24 EMD66875.1 - 1.6e-19 69.9 0.0 5.1e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMD66875.1 - 1.6e-09 37.8 0.2 1.4e-08 34.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMD66875.1 - 4e-06 26.5 0.4 1.1e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 EMD66875.1 - 0.0055 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_10 PF12846.2 EMD66876.1 - 1.7e-10 40.8 0.6 2.1e-07 30.6 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain Zot PF05707.7 EMD66876.1 - 4.3e-06 26.3 0.1 1.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EMD66876.1 - 0.0023 18.0 0.1 0.58 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 EMD66876.1 - 0.0025 16.2 0.0 0.0038 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) VOMI PF03762.12 EMD66876.1 - 0.036 14.0 0.5 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Vitelline membrane outer layer protein I (VOMI) DUF87 PF01935.12 EMD66876.1 - 0.08 12.7 0.4 0.81 9.4 0.2 2.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF3816 PF12822.2 EMD66878.1 - 0.02 14.7 22.3 0.065 13.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) Mem_trans PF03547.13 EMD66878.1 - 0.025 12.8 3.8 0.007 14.7 0.3 1.9 2 0 0 2 2 2 0 Membrane transport protein OppC_N PF12911.2 EMD66878.1 - 0.72 9.2 8.1 15 5.0 0.0 4.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C PE PF00934.15 EMD66879.1 - 0.15 12.1 2.6 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 PE family FAD_binding_3 PF01494.14 EMD66880.1 - 2.4e-14 53.1 0.2 1e-13 51.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD66880.1 - 8e-08 31.5 2.3 0.00064 18.7 0.0 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD66880.1 - 0.00058 18.8 0.3 0.002 17.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD66880.1 - 0.0046 15.4 0.1 0.015 13.8 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMD66880.1 - 0.017 14.0 0.1 0.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMD66880.1 - 0.028 14.2 0.0 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD66880.1 - 0.037 13.1 0.5 0.068 12.2 0.1 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMD66880.1 - 0.038 12.6 0.2 4.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Trp_halogenase PF04820.9 EMD66881.1 - 5.4e-28 97.8 0.2 4.6e-14 51.8 0.0 2.4 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EMD66881.1 - 1e-12 47.8 0.0 4.1e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD66881.1 - 6.2e-07 29.5 0.0 1.5e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD66881.1 - 1.6e-06 27.2 0.0 1.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD66881.1 - 2.1e-06 27.1 0.2 4.4e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD66881.1 - 7.5e-06 24.6 0.3 4e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMD66881.1 - 2.9e-05 23.0 0.4 6.6e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMD66881.1 - 5.9e-05 23.0 0.7 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD66881.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMD66881.1 - 0.00025 20.2 0.4 0.0018 17.4 0.0 2.6 4 0 0 4 4 4 1 Thi4 family Lycopene_cycl PF05834.7 EMD66881.1 - 0.005 15.8 0.4 0.04 12.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMD66881.1 - 0.016 15.6 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMD66881.1 - 0.031 13.9 0.2 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EMD66881.1 - 0.032 14.2 0.0 0.059 13.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMD66881.1 - 0.095 12.5 0.5 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 ThiF family ComX PF05952.7 EMD66881.1 - 0.12 11.9 0.0 23 4.5 0.0 2.5 2 0 0 2 2 2 0 Bacillus competence pheromone ComX ketoacyl-synt PF00109.21 EMD66882.1 - 5.3e-69 232.5 0.1 5.3e-69 232.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD66882.1 - 5.9e-48 163.8 0.0 1.1e-47 162.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD66882.1 - 1.1e-33 115.5 1.5 3.1e-33 114.1 1.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMD66882.1 - 2.6e-12 46.8 0.2 8.4e-12 45.1 0.2 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EMD66882.1 - 9.3e-05 22.2 0.8 0.00059 19.6 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EMD66882.1 - 0.0013 17.7 0.1 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyoxalase_2 PF12681.2 EMD66882.1 - 0.031 14.8 0.1 0.34 11.5 0.0 2.7 3 0 0 3 3 3 0 Glyoxalase-like domain Lactamase_B PF00753.22 EMD66883.1 - 2.4e-22 79.5 0.4 3.6e-22 78.9 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD66883.1 - 5.7e-06 26.0 0.1 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EthD PF07110.6 EMD66884.1 - 8.7e-21 74.6 0.5 1.1e-20 74.3 0.4 1.1 1 0 0 1 1 1 1 EthD domain DUF4243 PF14027.1 EMD66885.1 - 1.2e-84 284.6 0.7 1.4e-84 284.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1139 PF06599.6 EMD66885.1 - 0.12 11.5 0.1 0.91 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) Scytalone_dh PF02982.9 EMD66886.1 - 9.5e-56 187.7 0.0 1.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMD66886.1 - 2.8e-07 30.4 0.1 3.8e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Peptidase_C71 PF12386.3 EMD66886.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei SnoaL_2 PF12680.2 EMD66887.1 - 3.9e-05 23.9 0.1 5.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EMD66887.1 - 0.0023 17.9 0.0 0.0068 16.4 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 EMD66887.1 - 0.041 13.4 0.0 0.051 13.1 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Methyltransf_11 PF08241.7 EMD66889.1 - 3.3e-17 62.7 0.1 6.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD66889.1 - 4.6e-11 43.0 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD66889.1 - 1.4e-10 41.7 0.1 3.2e-10 40.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD66889.1 - 4.4e-10 39.3 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD66889.1 - 1.6e-08 34.8 0.1 4.1e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD66889.1 - 2.4e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD66889.1 - 2.7e-05 24.1 1.3 7.7e-05 22.7 0.8 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD66889.1 - 0.00068 18.8 0.0 0.0072 15.4 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMD66889.1 - 0.0033 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NAD_binding_10 PF13460.1 EMD66890.1 - 7e-22 78.3 0.0 8.8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD66890.1 - 9.4e-06 24.5 0.0 2.2e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMD66890.1 - 1.2e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMD66890.1 - 1.9e-05 24.9 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMD66890.1 - 2.4e-05 23.9 0.0 4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMD66890.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EMD66890.1 - 0.031 13.2 0.0 0.069 12.0 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein KR PF08659.5 EMD66890.1 - 0.051 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1772 PF08592.6 EMD66891.1 - 1.1e-23 83.5 3.0 1.3e-23 83.2 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) 7TM_GPCR_Srsx PF10320.4 EMD66891.1 - 0.018 14.1 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2561 PF10812.3 EMD66891.1 - 0.023 14.2 0.2 0.039 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4149 PF13664.1 EMD66891.1 - 0.35 10.9 3.1 0.6 10.2 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) adh_short PF00106.20 EMD66892.1 - 4.5e-32 111.2 2.5 5.7e-32 110.9 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD66892.1 - 3.9e-28 98.8 0.4 4.8e-28 98.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD66892.1 - 1.4e-16 60.7 2.2 1.9e-16 60.2 1.5 1.1 1 0 0 1 1 1 1 KR domain DUF460 PF04312.8 EMD66892.1 - 0.0084 15.6 0.3 0.02 14.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF460) Peripla_BP_6 PF13458.1 EMD66892.1 - 0.021 14.2 0.7 0.066 12.5 0.5 1.9 1 1 0 1 1 1 0 Periplasmic binding protein B12-binding PF02310.14 EMD66892.1 - 0.021 14.6 0.3 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 B12 binding domain Eno-Rase_NADH_b PF12242.3 EMD66892.1 - 0.047 13.4 0.4 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMD66892.1 - 0.078 12.4 0.5 0.24 10.7 0.4 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4267 PF14087.1 EMD66893.1 - 4.4e-10 39.1 4.8 5.5e-10 38.8 2.7 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4267) FAD_binding_3 PF01494.14 EMD66894.1 - 1.3e-16 60.5 0.0 2.5e-16 59.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EMD66894.1 - 0.0021 16.9 0.0 0.69 8.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.19 EMD66894.1 - 0.022 13.8 0.1 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMD66894.1 - 0.023 14.4 0.1 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMD66894.1 - 0.028 13.0 0.7 6.7 5.2 0.0 3.1 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.19 EMD66894.1 - 0.038 12.9 1.5 0.91 8.3 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 EMD66895.1 - 0.0017 17.3 0.1 0.0031 16.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66895.1 - 0.0056 16.5 13.2 0.014 15.2 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG19_autophagy PF12744.2 EMD66895.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding MFS_1 PF07690.11 EMD66896.1 - 2e-36 125.4 51.8 2e-36 125.4 35.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD66896.1 - 5.9e-09 34.6 26.0 1.7e-08 33.1 17.8 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AflR PF08493.5 EMD66897.1 - 3.3e-12 46.0 0.3 3.3e-12 46.0 0.2 2.9 1 1 1 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EMD66897.1 - 4.3e-05 23.3 7.9 7.3e-05 22.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_5 PF00941.16 EMD66897.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase DUF1090 PF06476.7 EMD66897.1 - 0.053 13.1 0.6 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Sugar_tr PF00083.19 EMD66898.1 - 1.6e-58 198.4 22.8 1.8e-58 198.2 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD66898.1 - 2.8e-16 59.2 22.4 2.8e-16 59.2 15.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sensor_TM1 PF13755.1 EMD66898.1 - 0.34 10.4 2.1 0.99 8.9 0.2 2.6 3 0 0 3 3 3 0 Sensor N-terminal transmembrane domain Caleosin PF05042.8 EMD66900.1 - 2e-57 193.5 0.0 2.7e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Pyr_redox PF00070.22 EMD66902.1 - 1.1e-17 64.1 0.1 2.2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD66902.1 - 1.2e-15 57.9 0.0 7.6e-15 55.3 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD66902.1 - 2.9e-09 36.3 0.0 2.2e-06 26.8 0.0 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMD66902.1 - 2.2e-08 34.3 0.1 0.0012 18.9 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD66902.1 - 2.8e-07 29.5 0.1 0.038 12.6 0.0 4.0 3 1 1 4 4 4 2 Tryptophan halogenase DAO PF01266.19 EMD66902.1 - 8.7e-07 28.1 0.0 0.0013 17.6 0.0 2.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD66902.1 - 4.6e-05 23.3 0.0 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD66902.1 - 0.00052 19.0 0.0 0.29 10.0 0.0 3.2 2 2 2 4 4 4 1 Lycopene cyclase protein TrkA_N PF02254.13 EMD66902.1 - 0.0017 18.3 0.0 0.58 10.1 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain HI0933_like PF03486.9 EMD66902.1 - 0.0075 14.7 0.0 6.9 5.0 0.0 3.2 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 EMD66902.1 - 0.025 14.3 0.0 36 4.1 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMD66902.1 - 0.076 12.0 0.1 0.46 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain TauD PF02668.11 EMD66904.1 - 1.5e-28 100.1 0.1 1.9e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF947 PF06102.7 EMD66904.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) AA_permease_2 PF13520.1 EMD66905.1 - 2.2e-71 240.6 39.0 2.7e-71 240.3 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD66905.1 - 2e-15 56.1 36.2 3.4e-15 55.3 25.1 1.4 1 1 0 1 1 1 1 Amino acid permease SNF PF00209.13 EMD66907.1 - 7.8e-76 255.6 34.7 2.7e-75 253.8 20.3 2.8 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family zf-GRF PF06839.7 EMD66909.1 - 0.042 13.7 1.0 0.097 12.6 0.7 1.6 1 0 0 1 1 1 0 GRF zinc finger Glyco_transf_34 PF05637.7 EMD66910.1 - 6.9e-27 94.4 3.0 4e-25 88.6 2.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EMD66910.1 - 0.0021 17.8 0.2 0.0049 16.6 0.1 1.5 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase Mito_fiss_reg PF05308.6 EMD66910.1 - 1.4 8.2 7.7 2.2 7.6 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Beta-lactamase PF00144.19 EMD66911.1 - 7e-29 100.8 0.2 1.6e-28 99.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase CTC1 PF15489.1 EMD66912.1 - 0.0062 13.9 0.0 0.0069 13.8 0.0 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 7tm_2 PF00002.19 EMD66914.1 - 0.0021 17.1 10.8 0.0078 15.3 7.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4064 PF13273.1 EMD66914.1 - 3.4 7.8 10.5 1.8 8.7 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) 2-Hacid_dh_C PF02826.14 EMD66915.1 - 4.5e-46 156.2 0.1 1.2e-29 102.7 0.0 2.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMD66915.1 - 0.00044 20.1 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 EMD66915.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 EMD66915.1 - 0.0094 15.3 0.1 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EMD66915.1 - 0.013 15.8 0.0 0.046 14.0 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain Gp_dh_N PF00044.19 EMD66915.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMD66915.1 - 0.029 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EMD66915.1 - 0.033 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMD66915.1 - 0.062 13.7 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EMD66915.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Oxidored_nitro PF00148.14 EMD66915.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF846 PF05832.7 EMD66916.1 - 7.8e-51 171.5 9.8 9.2e-51 171.2 6.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_hydroxylase PF04116.8 EMD66916.1 - 0.66 10.3 4.5 2.9 8.3 0.4 2.1 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily HpcH_HpaI PF03328.9 EMD66917.1 - 1.1e-44 151.9 0.0 1.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EMD66917.1 - 2.8e-14 52.7 0.1 5.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Methyltransf_28 PF02636.12 EMD66918.1 - 8.4e-36 123.6 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.20 EMD66919.1 - 3.3e-55 187.4 1.1 5.1e-55 186.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_C PF08544.8 EMD66919.1 - 0.06 13.5 0.1 4.5 7.5 0.0 3.1 3 0 0 3 3 3 0 GHMP kinases C terminal Abhydrolase_4 PF08386.5 EMD66921.1 - 7.5e-24 83.6 0.0 1.8e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMD66921.1 - 4.1e-17 62.5 0.1 5.5e-09 35.9 0.1 3.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD66921.1 - 2.1e-10 40.8 0.0 3.7e-09 36.8 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD66921.1 - 0.00022 20.9 0.1 0.34 10.6 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family RRM_1 PF00076.17 EMD66922.1 - 1.7e-23 82.0 0.0 2.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD66922.1 - 1.6e-16 60.0 0.0 2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD66922.1 - 7.4e-09 35.3 0.0 9.5e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD66922.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Limkain b1 Pyrophosphatase PF00719.14 EMD66924.1 - 4.3e-54 182.1 0.2 5.7e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EMD66925.1 - 9.6e-22 76.7 0.2 1.4e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 EMD66926.1 - 1.7e-16 59.6 1.4 1.7e-16 59.6 1.0 2.0 2 0 0 2 2 2 1 Sec20 Cys_Met_Meta_PP PF01053.15 EMD66927.1 - 1.5e-139 464.6 0.3 1.7e-139 464.4 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD66927.1 - 2.6e-10 39.8 0.1 4.3e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMD66927.1 - 4.3e-07 29.3 0.1 7.9e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMD66927.1 - 7.2e-06 24.9 0.6 1.4e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMD66927.1 - 0.0027 16.8 0.3 0.0076 15.4 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Atg14 PF10186.4 EMD66928.1 - 1.2e-86 290.3 0.2 1.5e-86 290.0 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 C1_3 PF07649.7 EMD66928.1 - 0.0068 16.4 2.5 0.012 15.6 1.7 1.4 1 0 0 1 1 1 1 C1-like domain Syntaxin PF00804.20 EMD66928.1 - 0.011 15.9 4.0 0.02 15.0 2.8 1.4 1 0 0 1 1 1 0 Syntaxin RasGAP_C PF03836.10 EMD66928.1 - 0.014 15.1 2.7 0.034 13.8 1.9 1.7 1 0 0 1 1 1 0 RasGAP C-terminus IncA PF04156.9 EMD66928.1 - 0.064 12.8 3.4 0.13 11.8 2.4 1.5 1 0 0 1 1 1 0 IncA protein DUF3810 PF12725.2 EMD66928.1 - 0.11 11.3 0.9 0.21 10.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) APG6 PF04111.7 EMD66928.1 - 1 8.3 11.9 10 5.0 8.2 2.2 1 1 0 1 1 1 0 Autophagy protein Apg6 Pyr_redox_2 PF07992.9 EMD66930.1 - 2.8e-29 102.4 4.8 1.6e-28 99.9 3.3 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD66930.1 - 3.6e-16 59.3 1.0 4.7e-14 52.5 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD66930.1 - 2e-11 44.3 0.5 7.3e-08 32.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD66930.1 - 3.6e-07 29.4 0.8 0.11 11.3 0.3 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD66930.1 - 5.6e-06 25.6 1.3 7.2e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMD66930.1 - 6.5e-06 25.4 1.5 0.0013 17.8 0.1 2.7 2 1 1 3 3 3 2 Thi4 family GIDA PF01134.17 EMD66930.1 - 1.4e-05 24.1 4.9 0.00039 19.4 0.3 3.6 3 2 1 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EMD66930.1 - 1.6e-05 24.0 0.9 0.013 14.4 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMD66930.1 - 0.00011 20.8 0.4 0.016 13.7 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EMD66930.1 - 0.00062 19.7 0.1 0.15 12.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD66930.1 - 0.0049 15.7 7.9 0.011 14.5 0.7 3.5 2 1 2 4 4 4 1 FAD binding domain NAD_binding_7 PF13241.1 EMD66930.1 - 0.0051 17.0 1.1 0.056 13.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMD66930.1 - 0.017 15.2 0.1 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EMD66930.1 - 0.03 12.9 0.3 0.58 8.7 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EMD66930.1 - 0.045 13.4 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WD40 PF00400.27 EMD66931.1 - 2.4e-06 27.2 0.3 0.0037 17.0 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 EMD66931.1 - 0.00097 18.3 0.0 0.0039 16.3 0.0 2.0 1 1 0 1 1 1 1 CPSF A subunit region Lactonase PF10282.4 EMD66931.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ribosomal_L10 PF00466.15 EMD66932.1 - 1.4e-26 92.3 0.1 2.5e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EMD66932.1 - 1.1e-22 80.2 5.0 3.9e-22 78.4 2.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Phage_holin PF04688.8 EMD66932.1 - 0.048 13.1 0.8 0.089 12.3 0.5 1.4 1 0 0 1 1 1 0 Phage lysis protein, holin Pox_Ag35 PF03286.9 EMD66932.1 - 0.14 11.6 0.4 10 5.5 0.0 3.3 4 0 0 4 4 4 0 Pox virus Ag35 surface protein FR47 PF08445.5 EMD66933.1 - 3.3e-05 23.5 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EMD66933.1 - 0.14 12.0 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Mito_carr PF00153.22 EMD66935.1 - 1.6e-66 220.0 4.4 5.1e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-B_box PF00643.19 EMD66936.1 - 0.00064 19.5 3.3 0.0011 18.8 2.3 1.2 1 0 0 1 1 1 1 B-box zinc finger zf-C3HC4_2 PF13923.1 EMD66936.1 - 0.32 11.0 4.9 0.52 10.3 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin_4 PF13462.1 EMD66937.1 - 3.8e-08 33.4 0.0 6.3e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EMD66937.1 - 0.022 14.3 4.2 1.2 8.6 0.1 3.0 2 1 0 2 2 2 0 DSBA-like thioredoxin domain PAH PF02671.16 EMD66938.1 - 1.3e-44 149.5 2.7 1.5e-18 66.1 0.1 4.2 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EMD66938.1 - 8.1e-39 131.4 0.0 8.1e-39 131.4 0.0 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor Glyco_hydro_3 PF00933.16 EMD66939.1 - 2.6e-83 279.4 0.0 3.7e-83 278.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD66939.1 - 2.8e-69 233.1 0.0 2.3e-68 230.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD66939.1 - 4.4e-20 71.3 0.1 9.8e-20 70.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMD66939.1 - 2.5e-19 69.3 0.0 4.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Myosin_head PF00063.16 EMD66940.1 - 4.3e-237 788.5 2.6 6.4e-237 787.9 1.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 EMD66940.1 - 1.4e-60 204.6 0.0 2.3e-60 203.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Myosin_TH1 PF06017.8 EMD66940.1 - 5.5e-46 156.4 0.0 1.2e-45 155.2 0.0 1.6 2 0 0 2 2 2 1 Myosin tail Pkinase_Tyr PF07714.12 EMD66940.1 - 8.4e-42 143.0 0.0 1.4e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EMD66940.1 - 2e-12 46.3 0.1 4.4e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD66940.1 - 2.1e-11 43.1 0.0 5.5e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMD66940.1 - 5e-10 38.7 0.0 1.4e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 EMD66940.1 - 1.7e-08 33.8 0.0 3.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EMD66940.1 - 6.1e-07 29.3 0.8 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region IQ PF00612.22 EMD66940.1 - 0.0022 17.5 4.1 0.83 9.4 0.7 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EMD66940.1 - 0.0032 17.5 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD66940.1 - 0.03 15.1 0.0 0.095 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD66940.1 - 0.04 14.2 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD66940.1 - 0.042 12.9 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EMD66940.1 - 0.071 12.4 0.5 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TrwB_AAD_bind PF10412.4 EMD66940.1 - 0.22 10.0 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain OPA3 PF07047.7 EMD66941.1 - 1.2e-29 102.7 10.4 6.4e-29 100.4 7.2 2.2 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) EAP30 PF04157.11 EMD66941.1 - 0.0066 15.6 3.8 0.025 13.7 0.0 2.7 3 0 0 3 3 3 1 EAP30/Vps36 family Med11 PF10280.4 EMD66941.1 - 0.14 12.2 1.7 5.4 7.0 0.2 2.6 1 1 1 2 2 2 0 Mediator complex protein Glycoprotein_G PF00802.14 EMD66942.1 - 0.082 12.0 1.9 0.091 11.9 0.7 1.4 1 1 0 1 1 1 0 Pneumovirus attachment glycoprotein G RNA_polI_A34 PF08208.6 EMD66942.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3712 PF12505.3 EMD66943.1 - 2.4e-34 118.0 5.4 1.5e-33 115.4 1.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EMD66943.1 - 0.0018 18.5 0.2 0.5 10.7 0.0 2.6 3 0 0 3 3 3 2 Late embryogenesis abundant protein DUF1279 PF06916.8 EMD66943.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF4187 PF13821.1 EMD66944.1 - 6.1e-17 60.9 1.1 2e-16 59.3 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EMD66944.1 - 1.4e-13 50.3 0.2 2.5e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMD66944.1 - 0.0029 17.4 3.5 0.0029 17.4 2.4 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site Dppa2_A PF14049.1 EMD66944.1 - 0.47 10.3 5.5 0.1 12.4 0.9 2.0 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates ORC3_N PF07034.6 EMD66945.1 - 3.1e-33 115.1 0.0 1.1e-32 113.2 0.0 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus RasGAP_C PF03836.10 EMD66945.1 - 0.14 11.8 2.6 0.18 11.4 0.2 2.3 2 0 0 2 2 2 0 RasGAP C-terminus FlaG PF03646.10 EMD66945.1 - 0.43 10.7 2.7 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 FlaG protein 3-HAO PF06052.7 EMD66946.1 - 3.4e-62 208.3 0.0 4.3e-62 208.0 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.14 EMD66946.1 - 1.6e-05 24.5 0.1 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.6 EMD66946.1 - 2.2e-05 23.8 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EMD66946.1 - 0.00051 19.5 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Cupin zf-dskA_traR PF01258.12 EMD66946.1 - 0.03 14.0 2.8 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ARD PF03079.9 EMD66946.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family DZR PF12773.2 EMD66946.1 - 0.041 13.6 7.5 0.037 13.8 3.7 2.0 2 0 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 EMD66946.1 - 0.11 12.0 3.8 6.1 6.4 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Nudix_N_2 PF14803.1 EMD66946.1 - 0.53 10.0 4.6 2.3 7.9 0.0 2.9 2 0 0 2 2 2 0 Nudix N-terminal ADK_lid PF05191.9 EMD66946.1 - 0.72 9.5 4.0 17 5.1 1.0 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.1 EMD66946.1 - 2.3 7.5 8.0 2.3 7.5 0.6 2.6 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EMD66946.1 - 5.6 6.7 6.4 3.1 7.5 0.2 2.4 1 1 2 3 3 2 0 Putative transposase DNA-binding domain YhfH PF14149.1 EMD66946.1 - 6 6.7 8.1 25 4.7 1.2 3.0 1 1 2 3 3 3 0 YhfH-like protein zinc_ribbon_2 PF13240.1 EMD66946.1 - 8.7 5.9 7.5 9.7 5.8 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Ctr PF04145.10 EMD66947.1 - 1.4e-33 115.9 8.2 2.9e-33 114.9 5.7 1.5 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 EMD66947.1 - 0.12 11.7 2.6 0.26 10.6 1.8 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 FAD_binding_2 PF00890.19 EMD66948.1 - 5.5e-81 272.5 0.4 6.6e-81 272.2 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EMD66948.1 - 1.9e-19 69.2 0.2 2.1e-17 62.6 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EMD66948.1 - 1.7e-11 43.6 0.6 7e-11 41.6 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD66948.1 - 1.9e-09 37.0 0.5 5.8e-09 35.5 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD66948.1 - 1.9e-08 34.1 0.5 2.2e-07 30.7 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMD66948.1 - 6.8e-07 28.1 1.9 0.0017 16.9 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMD66948.1 - 1.3e-06 28.4 0.0 0.00011 22.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD66948.1 - 1.4e-05 24.3 0.6 0.0064 15.6 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EMD66948.1 - 0.00023 20.1 1.3 0.011 14.6 0.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EMD66948.1 - 0.00055 19.1 0.1 1.2 8.1 0.0 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMD66948.1 - 0.0016 18.5 1.3 0.0043 17.1 0.6 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD66948.1 - 0.0035 16.4 1.0 0.0061 15.6 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMD66948.1 - 0.005 16.6 0.6 0.061 13.0 0.4 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding IF2_N PF04760.10 EMD66948.1 - 0.006 16.2 0.5 0.015 14.9 0.3 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region 3HCDH_N PF02737.13 EMD66948.1 - 0.029 14.0 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMD66948.1 - 0.13 12.6 0.5 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.23 EMD66949.1 - 5.3e-09 35.7 7.5 3.8e-08 32.9 5.2 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_2c PF01411.14 EMD66950.1 - 1.7e-215 716.5 0.0 2.4e-215 715.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMD66950.1 - 4e-17 61.8 0.2 1.3e-16 60.1 0.2 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EMD66950.1 - 8.5e-05 22.1 0.1 0.00032 20.3 0.1 2.1 1 0 0 1 1 1 1 DHHA1 domain DUF1546 PF07571.8 EMD66950.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) NRDE-2 PF08424.5 EMD66951.1 - 0.012 14.5 0.4 0.045 12.6 0.3 1.7 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference RCR PF12273.3 EMD66952.1 - 2.7e-07 31.1 2.7 2.7e-07 31.1 1.8 2.1 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red zf-HC5HC2H_2 PF13832.1 EMD66953.1 - 7.8e-18 64.4 2.7 7.8e-18 64.4 1.9 4.1 3 1 1 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.13 EMD66953.1 - 2.2e-14 53.2 0.2 5.6e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 EMD66953.1 - 1.2e-13 51.0 4.5 1.2e-13 51.0 3.2 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 EMD66953.1 - 1.6e-10 40.4 54.8 3.8e-07 29.7 5.9 6.0 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.1 EMD66953.1 - 2.6e-09 36.2 4.4 2.6e-09 36.2 3.1 5.0 6 0 0 6 6 6 2 PHD-finger Helicase_C PF00271.26 EMD66955.1 - 9.8e-20 70.2 0.0 3e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD66955.1 - 1.1e-19 70.9 0.0 2.5e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD66955.1 - 3.3e-19 68.9 0.0 7.7e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EMD66955.1 - 0.051 12.5 0.1 0.23 10.3 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMD66955.1 - 0.062 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain OAD_gamma PF04277.8 EMD66955.1 - 7.3 7.0 6.2 58 4.1 0.0 3.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ERO1 PF04137.10 EMD66956.1 - 1.9e-138 461.3 0.0 2.3e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PRY PF13765.1 EMD66956.1 - 0.03 13.8 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 SPRY-associated domain G3P_acyltransf PF02660.10 EMD66958.1 - 0.025 14.1 3.5 0.027 14.0 2.4 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase OPT PF03169.10 EMD66958.1 - 0.045 12.1 2.6 0.042 12.2 1.8 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Pex24p PF06398.6 EMD66958.1 - 0.065 12.0 0.6 0.061 12.1 0.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MARVEL PF01284.18 EMD66958.1 - 0.1 12.3 4.9 0.13 12.1 3.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2244 PF10003.4 EMD66958.1 - 0.43 9.9 3.1 0.55 9.5 2.2 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF1700 PF08006.6 EMD66958.1 - 0.47 9.7 8.8 0.55 9.5 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3099 PF11298.3 EMD66958.1 - 3.4 7.4 5.6 7.2 6.4 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) Herpes_LMP1 PF05297.6 EMD66958.1 - 6.3 5.6 5.6 7.5 5.3 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2207 PF09972.4 EMD66958.1 - 6.6 5.1 5.5 7.2 5.0 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ORC6 PF05460.8 EMD66959.1 - 0.0021 17.2 3.8 0.0026 16.9 2.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 EMD66959.1 - 0.64 9.5 6.7 1 8.8 4.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F_actin_cap_B PF01115.12 EMD66960.1 - 6.2e-109 362.8 0.0 7.3e-109 362.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RNase_PH_C PF03725.10 EMD66960.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Peptidase_M10 PF00413.19 EMD66961.1 - 1.8e-16 60.2 0.0 3.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 EMD66961.1 - 0.0039 17.7 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EMD66961.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.4 EMD66961.1 - 0.033 13.0 0.7 0.054 12.3 0.5 1.5 1 1 0 1 1 1 0 Peptidase M66 Glyco_transf_64 PF09258.5 EMD66961.1 - 0.041 13.0 0.1 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Metallopep PF12044.3 EMD66961.1 - 0.043 12.2 0.1 0.085 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 EMD66961.1 - 0.044 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMD66961.1 - 0.26 10.7 1.5 0.66 9.4 0.5 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Fungal_trans PF04082.13 EMD66962.1 - 1.1e-27 96.6 3.9 1.6e-27 96.0 2.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD66962.1 - 1.5e-10 40.8 12.9 1.5e-10 40.8 9.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YscK PF06578.7 EMD66962.1 - 0.079 12.3 1.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 YOP proteins translocation protein K (YscK) adh_short_C2 PF13561.1 EMD66963.1 - 6.8e-20 71.8 0.1 8.8e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD66963.1 - 3.1e-10 40.2 0.4 4.5e-10 39.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD66963.1 - 0.00031 20.4 0.8 0.0005 19.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMD66963.1 - 0.0049 16.8 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EMD66963.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Thioredoxin PF00085.15 EMD66964.1 - 1.3e-30 105.1 4.6 3.2e-25 87.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EMD66964.1 - 1e-09 38.4 0.2 2.2e-07 30.8 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EMD66964.1 - 4.1e-07 30.1 5.1 0.0051 16.9 0.2 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMD66964.1 - 3.4e-05 23.8 0.0 0.015 15.3 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin-like HTH_6 PF01418.12 EMD66964.1 - 0.029 14.0 0.0 0.52 10.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Thioredoxin_7 PF13899.1 EMD66964.1 - 0.031 14.3 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EMD66964.1 - 0.31 10.9 5.0 2.1 8.2 0.1 3.2 3 0 0 3 3 3 0 Thioredoxin domain DUF605 PF04652.11 EMD66965.1 - 1.3e-76 258.4 41.9 3e-76 257.2 29.0 1.8 1 1 0 1 1 1 1 Vta1 like Sec1 PF00995.18 EMD66966.1 - 1.7e-119 400.0 0.0 1.9e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Rax2 PF12768.2 EMD66967.1 - 2.8e-92 308.9 9.2 8.1e-89 297.5 0.1 4.9 4 1 1 5 5 5 4 Cortical protein marker for cell polarity Reg_prop PF07494.6 EMD66967.1 - 0.014 15.3 0.8 1.5 9.0 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller Kelch_2 PF07646.10 EMD66967.1 - 0.033 13.9 0.6 18 5.3 0.0 4.1 5 0 0 5 5 5 0 Kelch motif MFS_1 PF07690.11 EMD66968.1 - 6.2e-42 143.5 59.9 6.2e-42 143.5 41.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD66968.1 - 2e-18 65.9 29.7 2.9e-18 65.4 20.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD66968.1 - 3e-14 52.4 14.1 3e-14 52.4 9.8 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter Glyco_hydro_18 PF00704.23 EMD66970.1 - 7.4e-81 272.2 0.0 8.8e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EMD66970.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) zf-CCCH PF00642.19 EMD66971.1 - 4.2e-17 61.3 38.6 1.5e-06 27.7 0.2 5.8 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMD66971.1 - 0.29 11.1 0.1 0.073 13.1 2.5 5.9 7 0 0 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type PVL_ORF50 PF07768.6 EMD66971.1 - 0.77 9.7 7.3 1.4 8.9 5.0 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family WD40 PF00400.27 EMD66972.1 - 1e-29 101.2 8.7 8.5e-08 31.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMD66972.1 - 0.00073 17.7 0.5 0.0076 14.4 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF3684 PF12449.3 EMD66972.1 - 0.48 7.9 2.5 2.1 5.8 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3684) Ribosomal_L37 PF08561.5 EMD66974.1 - 3.4e-26 90.6 6.3 1.5e-24 85.3 4.4 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 PRCC PF10253.4 EMD66974.1 - 0.039 14.6 2.7 0.095 13.3 1.9 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TMEM61 PF15105.1 EMD66974.1 - 0.04 13.4 1.3 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 TMEM61 protein family DUF963 PF06131.6 EMD66974.1 - 7.1 5.9 11.2 0.13 11.5 3.0 1.7 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF726 PF05277.7 EMD66975.1 - 3.1e-126 420.9 3.0 4.5e-126 420.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.7 EMD66976.1 - 1.2e-26 92.6 0.3 2.3e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 Fcf1 Abhydrolase_6 PF12697.2 EMD66977.1 - 2.3e-17 63.6 1.1 3.2e-17 63.1 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD66977.1 - 7.4e-09 35.5 0.1 1.4e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD66977.1 - 3.1e-05 23.6 0.0 0.055 13.0 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMD66977.1 - 0.0048 16.3 0.0 0.088 12.2 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EMD66977.1 - 0.052 13.1 0.1 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMD66977.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EMD66977.1 - 0.18 11.5 0.0 8 6.1 0.0 2.1 2 0 0 2 2 2 0 Cutinase PAF-AH_p_II PF03403.8 EMD66977.1 - 0.23 9.7 0.5 11 4.1 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2417 PF10329.4 EMD66978.1 - 2.2e-88 295.5 0.4 3.2e-88 295.0 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EMD66978.1 - 7.3e-06 26.0 0.1 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2269 PF10027.4 EMD66978.1 - 0.002 17.9 4.4 0.002 17.9 3.1 2.2 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) Pal1 PF08316.6 EMD66979.1 - 1.6e-07 31.8 3.0 1.8e-07 31.7 0.0 2.4 3 0 0 3 3 3 1 Pal1 cell morphology protein HVSL PF09749.4 EMD66980.1 - 1.3e-74 250.1 0.0 1.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein CMV_US PF08001.6 EMD66980.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 CMV US Glyco_hydro_17 PF00332.13 EMD66982.1 - 4.2e-05 22.7 0.0 0.0031 16.5 0.1 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 DUF1294 PF06961.8 EMD66983.1 - 9e-24 83.1 0.3 1.7e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) DUF4199 PF13858.1 EMD66984.1 - 0.0031 17.4 0.1 0.0039 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) MMS19_C PF12460.3 EMD66984.1 - 0.066 11.9 0.0 0.083 11.5 0.0 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Neur_chan_memb PF02932.11 EMD66984.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 EMD66985.1 - 3.9e-72 242.5 0.0 5.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD66985.1 - 9.1e-38 129.8 0.0 1.3e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD66985.1 - 2.5e-05 23.3 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMD66985.1 - 0.0002 20.7 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EMD66985.1 - 0.0057 15.7 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.20 EMD66986.1 - 6.2e-36 122.1 1.5 4.4e-20 71.3 0.1 2.8 3 0 0 3 3 3 2 Bromodomain RabGAP-TBC PF00566.13 EMD66987.1 - 1e-34 119.8 0.0 2.9e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Cupin_8 PF13621.1 EMD66988.1 - 8.2e-14 51.6 0.0 1.6e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EMD66988.1 - 4.7e-09 36.4 0.0 1.6e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EMD66988.1 - 6.2e-07 29.0 0.2 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD66988.1 - 1.4e-06 27.7 0.2 2.8e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EMD66988.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Helicase_C PF00271.26 EMD66989.1 - 7.7e-28 96.1 0.6 4.8e-27 93.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD66989.1 - 2.8e-16 59.4 2.9 1.9e-15 56.7 1.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase DUF1253 PF06862.7 EMD66989.1 - 0.0025 16.3 0.0 0.57 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 EMD66989.1 - 0.004 17.0 0.1 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMD66989.1 - 0.023 14.4 0.4 0.077 12.7 0.3 1.9 1 1 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EMD66989.1 - 0.027 14.0 0.5 0.062 12.8 0.2 1.6 2 0 0 2 2 2 0 AAA domain Fanconi_A PF03511.9 EMD66989.1 - 0.09 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein NUDIX PF00293.23 EMD66990.1 - 1.9e-14 53.4 0.1 7.1e-14 51.5 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain SLAC1 PF03595.12 EMD66991.1 - 2.8e-77 259.6 37.4 3.2e-77 259.3 25.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel APH PF01636.18 EMD66993.1 - 4.9e-34 118.1 0.0 6.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD66993.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EMD66993.1 - 0.0055 15.8 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.15 EMD66993.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinesin PF00225.18 EMD66994.1 - 7.5e-114 379.9 0.0 1.3e-113 379.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EMD66994.1 - 1.4e-38 131.6 0.0 2.8e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EMD66994.1 - 6e-07 29.6 0.0 1.9e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 EMD66994.1 - 2e-05 24.4 2.1 5.9e-05 23.0 1.4 1.9 1 0 0 1 1 1 1 Kinesin protein 1B AAA_22 PF13401.1 EMD66994.1 - 0.089 12.9 0.6 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Met_10 PF02475.11 EMD66995.1 - 8.5e-68 227.8 0.0 1.2e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EMD66995.1 - 0.0035 16.3 0.0 0.0076 15.2 0.0 1.5 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase HATPase_c PF02518.21 EMD66996.1 - 2.1e-12 46.7 0.0 5.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMD66996.1 - 8.8e-12 44.8 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EMD66996.1 - 0.0063 15.9 0.0 0.088 12.2 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain SH3_5 PF08460.5 EMD66996.1 - 0.14 12.0 0.1 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Ada_Zn_binding PF02805.11 EMD66997.1 - 5.5e-29 99.5 6.2 1.3e-28 98.3 3.7 1.9 2 0 0 2 2 2 1 Metal binding domain of Ada PA_decarbox PF05870.6 EMD67000.1 - 1e-10 41.2 0.3 1.2e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Transp_cyt_pur PF02133.10 EMD67001.1 - 1.6e-94 316.9 32.4 1.9e-94 316.7 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EMD67002.1 - 1.6e-114 382.1 0.7 1.6e-114 382.1 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EMD67002.1 - 2.3e-50 171.3 9.5 5.5e-49 166.8 1.1 3.8 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMD67002.1 - 5.6e-30 104.1 0.3 3.6e-27 94.9 0.1 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EMD67002.1 - 1.8e-06 27.4 3.8 0.00048 19.5 0.1 3.4 3 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 EMD67002.1 - 3.6e-05 22.2 0.8 0.019 13.3 0.0 2.3 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EMD67002.1 - 0.0016 17.4 0.1 0.94 8.3 0.0 2.5 2 0 0 2 2 2 2 StbA protein Mito_carr PF00153.22 EMD67003.1 - 1.2e-63 210.8 2.5 6.1e-22 77.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.1 EMD67003.1 - 0.031 14.2 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Pyr_redox_3 PF13738.1 EMD67004.1 - 1.7e-13 51.1 0.0 4e-05 23.7 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD67004.1 - 4.3e-08 32.4 0.0 0.011 14.6 0.0 2.8 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD67004.1 - 1.2e-07 31.8 0.0 0.0016 18.3 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD67004.1 - 5.1e-05 23.2 0.1 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMD67004.1 - 0.00014 21.0 0.0 0.0042 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD67004.1 - 0.0004 18.9 0.0 0.0013 17.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EMD67004.1 - 0.00045 19.2 0.1 0.78 8.5 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD67004.1 - 0.00075 18.4 0.0 0.0016 17.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMD67004.1 - 0.00089 19.6 0.0 1.3 9.4 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMD67004.1 - 0.0009 18.7 0.0 0.013 14.9 0.0 2.5 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EMD67004.1 - 0.0013 17.7 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMD67004.1 - 0.0018 18.1 0.0 0.11 12.2 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EMD67004.1 - 0.026 14.6 0.1 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EMD67004.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EMD67004.1 - 0.18 11.5 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EMD67004.1 - 0.19 10.7 0.5 0.37 9.8 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_34 PF05637.7 EMD67006.1 - 2.3e-16 60.0 0.7 4.9e-16 58.9 0.5 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_8 PF01501.15 EMD67006.1 - 0.0047 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Hce2 PF14856.1 EMD67007.1 - 8.1e-27 92.9 0.4 9.8e-27 92.7 0.3 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HDPD PF02924.9 EMD67008.1 - 0.014 15.2 0.2 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D UPF0640 PF15114.1 EMD67008.1 - 0.15 11.5 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 DUF165 PF02592.10 EMD67010.1 - 0.029 14.5 0.9 0.062 13.4 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF454 PF04304.8 EMD67010.1 - 6.9 6.7 6.4 5.5 7.0 1.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF454) 5TM-5TMR_LYT PF07694.7 EMD67014.1 - 0.25 10.6 7.9 0.96 8.7 2.3 2.1 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Abhydrolase_6 PF12697.2 EMD67015.1 - 6.7e-07 29.4 0.1 8.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMD67015.1 - 9.3e-07 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMD67015.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMD67015.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EMD67015.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase Lipase_3 PF01764.20 EMD67015.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Exo_endo_phos_2 PF14529.1 EMD67016.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Ank_2 PF12796.2 EMD67017.1 - 2.4e-07 30.9 0.2 0.0014 18.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD67017.1 - 0.0041 16.8 0.0 0.25 11.2 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EMD67017.1 - 0.055 14.0 0.2 3.3 8.3 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67017.1 - 0.13 12.6 0.3 20 5.7 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeat HET PF06985.6 EMD67020.1 - 4.6e-18 65.7 0.3 5.8e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 EMD67021.1 - 9e-07 29.0 0.0 9.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EMD67021.1 - 3.2e-05 23.6 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EMD67021.1 - 0.00023 20.8 0.7 0.0005 19.7 0.1 1.7 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 EMD67021.1 - 0.00028 19.9 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EMD67021.1 - 0.0015 18.6 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EMD67021.1 - 0.0066 15.3 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain GvpD PF07088.6 EMD67021.1 - 0.0073 14.6 0.0 0.0082 14.5 0.0 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA PF00004.24 EMD67021.1 - 0.0092 16.1 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EMD67021.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EMD67021.1 - 0.014 14.0 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EMD67021.1 - 0.017 15.2 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMD67021.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EMD67021.1 - 0.026 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMD67021.1 - 0.027 13.5 0.0 0.045 12.8 0.0 1.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EMD67021.1 - 0.039 14.7 0.6 0.82 10.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EMD67021.1 - 0.051 13.8 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMD67021.1 - 0.055 12.8 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMD67021.1 - 0.056 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 EMD67021.1 - 0.068 13.0 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 EMD67021.1 - 0.085 12.3 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EMD67021.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Sigma54_activ_2 PF14532.1 EMD67021.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 EMD67021.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.16 EMD67021.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Lactamase_B PF00753.22 EMD67023.1 - 5.2e-10 39.2 0.5 1.4e-09 37.8 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD67023.1 - 0.011 15.3 0.1 0.016 14.7 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain HTH_Tnp_Tc5 PF03221.11 EMD67024.1 - 6.5e-10 38.6 0.3 1.4e-09 37.5 0.2 1.6 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD67024.1 - 5e-07 29.1 0.1 9.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EMD67024.1 - 0.00039 20.3 0.2 0.00097 19.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EMD67024.1 - 0.00096 18.7 0.5 0.005 16.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain NUMOD1 PF07453.8 EMD67024.1 - 0.021 14.6 0.3 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 NUMOD1 domain HTH_29 PF13551.1 EMD67024.1 - 0.042 14.0 0.3 0.079 13.1 0.2 1.5 1 1 0 1 1 1 0 Winged helix-turn helix APO_RNA-bind PF05634.6 EMD67024.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding HTH_AsnC-type PF13404.1 EMD67024.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PNP_UDP_1 PF01048.15 EMD67025.1 - 3.8e-11 42.4 0.3 6.1e-11 41.7 0.2 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily DDRGK PF09756.4 EMD67026.1 - 2.4 7.5 9.5 2.8 7.3 6.6 1.1 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 EMD67026.1 - 3.8 5.6 7.1 3.9 5.6 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Spb1_C PF07780.7 EMD67026.1 - 7.3 6.0 15.3 8.3 5.8 10.6 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain HTH_Tnp_Tc5 PF03221.11 EMD67027.1 - 8.2e-10 38.3 0.4 1.3e-09 37.7 0.0 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD67027.1 - 2.2e-06 27.0 0.2 3.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD67027.1 - 0.0018 18.4 0.3 0.0024 17.9 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMD67027.1 - 0.031 14.2 0.1 0.15 12.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD67027.1 - 0.058 13.0 0.3 0.24 11.0 0.0 2.3 2 2 0 2 2 2 0 Homeodomain-like domain Ribosomal_S13_N PF08069.7 EMD67027.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain HTH_Tnp_1 PF01527.15 EMD67027.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Transposase Cdc6_C PF09079.6 EMD67027.1 - 0.092 12.4 0.0 5.4 6.8 0.0 2.2 1 1 1 2 2 2 0 CDC6, C terminal HTH_36 PF13730.1 EMD67027.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 2 1 0 2 2 2 0 Helix-turn-helix domain HET PF06985.6 EMD67028.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Arylsulfotran_2 PF14269.1 EMD67030.1 - 6.3e-76 255.3 1.7 9.2e-76 254.8 1.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMD67030.1 - 0.0016 17.0 1.4 0.0036 15.8 1.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfatase PF00884.18 EMD67031.1 - 4.8e-48 163.9 0.1 2.7e-46 158.1 0.1 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMD67031.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase UCH PF00443.24 EMD67032.1 - 2e-12 46.8 0.2 3.5e-11 42.7 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD67032.1 - 6.3e-06 25.8 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Med27 PF11571.3 EMD67032.1 - 0.084 13.0 0.5 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 27 ADH_zinc_N PF00107.21 EMD67033.1 - 8.3e-24 83.6 0.1 1.2e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD67033.1 - 6.6e-18 64.4 0.3 1.1e-17 63.7 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMD67033.1 - 1.2e-05 26.1 0.0 2.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EMD67034.1 - 1.5e-39 135.4 0.0 2.4e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD67034.1 - 1.1e-20 73.8 0.0 1.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMD67034.1 - 1.9e-07 31.3 0.0 5.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMD67034.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMD67034.1 - 0.022 14.7 0.1 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EMD67034.1 - 0.044 14.3 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CMD PF02627.15 EMD67035.1 - 8e-10 38.4 0.1 1.9e-07 30.8 0.1 2.3 1 1 0 1 1 1 1 Carboxymuconolactone decarboxylase family Aldedh PF00171.17 EMD67036.1 - 1.1e-147 492.1 0.0 1.2e-147 491.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD67036.1 - 0.0059 15.8 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Myosin_N PF02736.14 EMD67036.1 - 0.14 11.8 0.2 0.4 10.4 0.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Abhydrolase_6 PF12697.2 EMD67037.1 - 6.7e-24 85.0 0.5 1.2e-23 84.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD67037.1 - 3.8e-10 39.7 0.1 1.2e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD67037.1 - 8.9e-10 38.5 0.1 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribonuc_L-PSP PF01042.16 EMD67038.1 - 4.6e-15 55.4 0.0 6.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sugar_tr PF00083.19 EMD67039.1 - 1.4e-71 241.4 28.4 1.6e-71 241.2 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD67039.1 - 2.1e-17 62.9 45.5 3.3e-09 35.9 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EMD67040.1 - 5.2e-10 38.6 4.5 7.8e-10 38.0 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMD67040.1 - 9e-08 32.0 11.2 0.00055 20.1 2.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD67040.1 - 5.6e-06 26.3 2.7 5.6e-06 26.3 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD67040.1 - 0.0057 16.9 16.7 0.0096 16.1 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger GlcNAc_2-epim PF07221.6 EMD67040.1 - 0.02 13.8 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) zf-C2H2_6 PF13912.1 EMD67040.1 - 0.16 11.9 8.5 1.2 9.0 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD67040.1 - 0.47 10.6 3.1 1.4 9.1 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Arginase PF00491.16 EMD67041.1 - 1.2e-30 106.8 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans PF04082.13 EMD67042.1 - 6.7e-22 77.5 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67042.1 - 5.8e-05 22.9 9.6 0.00011 22.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EMD67044.1 - 8e-16 57.6 1.0 8.5e-16 57.5 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD67044.1 - 3.2e-05 22.8 2.9 4e-05 22.4 2.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CN_hydrolase PF00795.17 EMD67045.1 - 3e-32 111.5 0.0 4e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Beta-lactamase PF00144.19 EMD67046.1 - 3.4e-37 128.2 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase NPP1 PF05630.6 EMD67047.1 - 4.1e-65 219.3 0.0 4.7e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) RVT_1 PF00078.22 EMD67050.1 - 0.0021 17.4 0.1 0.0021 17.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.16 EMD67051.1 - 1.5e-48 165.1 0.1 1.9e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 EMD67052.1 - 0.00055 20.1 0.0 0.0032 17.6 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.8 EMD67053.1 - 2.4e-13 50.6 0.1 3.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_transf_8 PF01501.15 EMD67054.1 - 5.6e-15 55.3 0.1 8.8e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 p450 PF00067.17 EMD67055.1 - 2e-60 204.6 0.0 2.4e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EMD67056.1 - 2.3e-18 66.4 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD67056.1 - 3.6e-11 43.4 0.0 6.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD67056.1 - 1.8e-09 37.3 0.0 7.1e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD67056.1 - 3.1e-09 37.2 0.0 1.4e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67056.1 - 1.2e-07 32.2 0.0 1.3e-06 28.9 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD67056.1 - 1.9e-05 24.9 0.0 4.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD67056.1 - 0.00012 22.0 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMD67056.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMD67056.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EMD67056.1 - 0.012 14.6 0.0 0.16 11.0 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EMD67056.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EMD67056.1 - 0.022 13.8 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.7 EMD67056.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MTS PF05175.9 EMD67056.1 - 0.03 13.6 0.0 0.094 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain UPF0146 PF03686.8 EMD67056.1 - 0.066 13.0 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) GTP_cyclohydroI PF01227.17 EMD67057.1 - 2.4e-73 245.2 0.1 3.4e-73 244.7 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EMD67057.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Pkinase PF00069.20 EMD67058.1 - 1.6e-69 233.9 0.0 2.7e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67058.1 - 1.9e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67058.1 - 0.00058 18.9 0.0 0.0014 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Peptidase_M14 PF00246.19 EMD67059.1 - 4.4e-21 75.7 0.0 6.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EMD67059.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) BNR_2 PF13088.1 EMD67060.1 - 0.00098 18.4 0.1 0.0024 17.2 0.1 1.6 1 1 0 1 1 1 1 BNR repeat-like domain Glyco_hydr_30_2 PF14587.1 EMD67061.1 - 1.7e-19 70.0 7.2 1.7e-19 70.0 5.0 1.6 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 DASH_Ask1 PF08655.5 EMD67061.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 Rieske PF00355.21 EMD67062.1 - 6.2e-10 38.5 0.0 9.1e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EMD67062.1 - 8.1e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Peptidase_S9 PF00326.16 EMD67064.1 - 0.00034 19.8 0.2 0.0032 16.6 0.1 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD67064.1 - 0.00046 19.9 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMD67064.1 - 0.021 14.0 0.0 0.057 12.6 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.7 EMD67064.1 - 0.023 13.2 0.1 0.088 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4118 PF13493.1 EMD67065.1 - 0.01 16.0 3.4 0.017 15.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) ERM PF00769.14 EMD67066.1 - 0.00039 20.0 34.8 0.068 12.6 6.5 3.0 2 1 0 2 2 2 2 Ezrin/radixin/moesin family DUF948 PF06103.6 EMD67066.1 - 0.012 15.4 5.1 0.45 10.3 0.1 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 EMD67066.1 - 0.017 15.4 26.3 0.13 12.6 1.7 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF972) IFT57 PF10498.4 EMD67066.1 - 0.079 11.6 24.1 0.058 12.1 8.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 APG6 PF04111.7 EMD67066.1 - 0.19 10.7 35.0 0.047 12.7 5.3 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 Cauli_AT PF03233.8 EMD67066.1 - 1.6 8.4 13.4 0.56 9.9 2.1 2.9 2 1 1 3 3 3 0 Aphid transmission protein Tropomyosin_1 PF12718.2 EMD67066.1 - 1.8 8.4 30.6 0.11 12.3 2.7 2.6 2 0 0 2 2 2 0 Tropomyosin like GAS PF13851.1 EMD67066.1 - 1.9 7.6 31.9 2.8 7.0 3.9 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 EMD67066.1 - 3.9 7.2 17.2 0.73 9.6 0.1 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper ATG16 PF08614.6 EMD67066.1 - 4.8 6.9 33.1 0.59 9.9 8.4 3.2 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Methyltransf_2 PF00891.13 EMD67068.1 - 4.7e-25 88.1 0.0 7.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase LSM PF01423.17 EMD67070.1 - 5.9e-06 25.7 0.0 8.1e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD67070.1 - 0.0021 17.9 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4242 PF14026.1 EMD67070.1 - 0.1 12.7 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) DUF2277 PF10041.4 EMD67071.1 - 0.043 13.7 0.0 0.34 10.8 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) TPR_6 PF13174.1 EMD67071.1 - 0.08 13.4 1.2 10 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EMD67073.1 - 4.3e-59 194.4 29.3 3.2e-12 45.8 0.1 12.6 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EMD67073.1 - 1.5e-28 98.8 0.0 2.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EMD67073.1 - 5.9e-07 29.3 0.1 0.0023 17.6 0.0 5.2 6 1 1 7 7 7 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMD67073.1 - 1.5e-05 23.3 6.2 0.049 11.7 0.0 4.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 IKI3 PF04762.7 EMD67073.1 - 0.00027 18.9 0.0 0.059 11.1 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 EMD67073.1 - 0.00032 19.9 0.2 1.9 7.5 0.0 4.1 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal CoiA PF06054.6 EMD67073.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family Hira PF07569.6 EMD67073.1 - 0.15 11.2 0.0 17 4.5 0.0 2.6 2 1 0 2 2 2 0 TUP1-like enhancer of split PTRF_SDPR PF15237.1 EMD67073.1 - 0.31 10.4 0.0 0.48 9.7 0.0 1.2 1 0 0 1 1 1 0 PTRF/SDPR family Septin PF00735.13 EMD67074.1 - 1.4e-114 381.8 0.3 1.9e-114 381.4 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMD67074.1 - 3.6e-07 30.1 0.0 6.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMD67074.1 - 6.7e-06 25.3 0.0 1.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMD67074.1 - 1.5e-05 24.4 1.3 8.4e-05 22.0 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMD67074.1 - 0.0012 19.0 0.2 0.0047 17.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EMD67074.1 - 0.0014 19.1 0.1 0.0041 17.6 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EMD67074.1 - 0.0027 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EMD67074.1 - 0.0082 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EMD67074.1 - 0.0093 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EMD67074.1 - 0.014 14.6 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AIG1 PF04548.11 EMD67074.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Ras PF00071.17 EMD67074.1 - 0.027 13.8 0.8 0.077 12.3 0.3 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.1 EMD67074.1 - 0.031 14.2 0.6 0.64 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 EMD67074.1 - 0.032 14.0 5.7 0.49 10.2 0.1 3.0 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EMD67074.1 - 0.044 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EMD67074.1 - 0.053 13.8 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EMD67074.1 - 0.054 12.3 0.3 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EMD67074.1 - 0.074 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 EMD67074.1 - 0.077 11.7 1.1 0.91 8.2 0.0 2.5 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 EMD67074.1 - 0.078 12.4 0.9 2.4 7.6 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EMD67074.1 - 0.093 12.2 1.1 9.5 5.6 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EMD67074.1 - 0.1 11.5 1.6 0.19 10.6 1.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain DUF1843 PF08898.5 EMD67074.1 - 0.27 11.3 2.3 0.56 10.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Atg14 PF10186.4 EMD67074.1 - 0.61 8.9 4.2 1.1 8.1 2.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 EMD67074.1 - 0.84 9.3 5.1 1 9.0 0.2 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EMD67074.1 - 7.8 6.7 12.9 86 3.3 9.0 2.1 1 1 0 1 1 1 0 AAA domain DUF3295 PF11702.3 EMD67075.1 - 0.052 12.5 3.8 0.068 12.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nucleo_P87 PF07267.6 EMD67075.1 - 0.27 9.8 1.1 0.32 9.6 0.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GMC_oxred_N PF00732.14 EMD67076.1 - 9.7e-28 97.1 0.0 2.6e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD67076.1 - 3.6e-19 69.5 0.1 3.6e-19 69.5 0.1 2.3 2 0 0 2 2 2 1 GMC oxidoreductase CBM_1 PF00734.13 EMD67076.1 - 1.2e-11 44.0 12.3 1.2e-11 44.0 8.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DAO PF01266.19 EMD67076.1 - 5.2e-07 28.8 0.0 0.0043 16.0 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD67076.1 - 5.9e-07 28.6 0.1 0.00078 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD67076.1 - 0.00067 19.6 0.3 0.0052 16.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMD67076.1 - 0.001 17.6 0.1 0.0017 16.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EMD67076.1 - 0.013 15.8 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD67076.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EMD67076.1 - 0.049 13.5 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 DOMON domain PSI PF01437.20 EMD67077.1 - 1.1e-05 25.5 4.7 2.2e-05 24.5 3.2 1.6 1 0 0 1 1 1 1 Plexin repeat MFS_1 PF07690.11 EMD67079.1 - 9.3e-25 87.0 58.8 1.5e-24 86.3 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tir_receptor_C PF07489.6 EMD67079.1 - 6.7 6.3 8.2 11 5.6 5.7 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 EMD67079.1 - 8.2 4.0 7.0 11 3.6 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein tRNA-synt_1e PF01406.14 EMD67080.1 - 5.6e-116 386.8 0.0 9.8e-116 386.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EMD67080.1 - 0.019 13.6 6.6 0.41 9.2 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 EMD67080.1 - 0.032 12.9 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Dna2 PF08696.6 EMD67080.1 - 0.12 11.6 0.1 11 5.2 0.0 2.7 3 0 0 3 3 3 0 DNA replication factor Dna2 GCD14 PF08704.5 EMD67081.1 - 1e-61 208.5 0.3 8.1e-22 77.9 0.0 3.9 3 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EMD67081.1 - 0.00049 20.1 0.0 0.0029 17.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67081.1 - 0.0011 19.5 0.2 0.46 11.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain PhoD PF09423.5 EMD67082.1 - 6.8e-58 196.3 0.0 8.6e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase HET PF06985.6 EMD67083.1 - 1.9e-19 70.2 8.5 1.8e-17 63.7 1.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Transferase PF02458.10 EMD67086.1 - 3.8e-32 111.2 0.0 2.7e-15 55.7 0.0 3.6 2 1 0 3 3 3 3 Transferase family ABC2_membrane PF01061.19 EMD67087.1 - 1.1e-87 292.6 53.5 2.1e-49 167.5 11.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMD67087.1 - 4.9e-41 140.2 0.0 5.1e-19 68.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD67087.1 - 7.3e-27 93.0 2.9 1.9e-24 85.2 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EMD67087.1 - 2.7e-15 56.2 33.6 4.5e-09 35.8 9.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 EMD67087.1 - 1.2e-06 28.7 0.0 0.013 15.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EMD67087.1 - 1.6e-06 27.6 0.0 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 EMD67087.1 - 3e-06 27.2 0.0 8.8e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EMD67087.1 - 1.2e-05 24.6 0.0 0.0069 15.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD67087.1 - 3e-05 24.0 0.1 0.02 14.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 EMD67087.1 - 0.0012 18.3 0.6 0.92 8.9 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD67087.1 - 0.0016 17.9 0.3 0.068 12.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EMD67087.1 - 0.0051 16.3 0.3 1.1 8.7 0.2 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EMD67087.1 - 0.0088 16.0 1.1 0.45 10.4 0.3 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD67087.1 - 0.011 16.5 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMD67087.1 - 0.02 14.8 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 EMD67087.1 - 0.02 15.0 0.0 7 6.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMD67087.1 - 0.024 14.8 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_21 PF13304.1 EMD67087.1 - 0.025 14.5 0.0 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EMD67087.1 - 0.035 13.8 0.8 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EMD67087.1 - 0.044 13.6 2.3 2.2 8.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EMD67087.1 - 0.055 13.9 0.0 16 6.0 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein NACHT PF05729.7 EMD67087.1 - 0.093 12.3 0.5 3.5 7.2 0.3 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 EMD67087.1 - 0.12 11.9 0.4 6.2 6.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMD67087.1 - 0.14 12.5 4.2 4.4 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EMD67087.1 - 0.15 11.7 1.0 3.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fungal_trans PF04082.13 EMD67088.1 - 9.8e-08 31.1 1.5 1.3e-07 30.8 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67088.1 - 1.1e-07 31.6 9.6 2.3e-07 30.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 EMD67090.1 - 3.3e-13 49.7 0.2 4.2e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3910 PF13049.1 EMD67090.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Peptidase_S15 PF02129.13 EMD67091.1 - 9.1e-38 130.2 4.3 6.2e-34 117.6 3.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMD67091.1 - 9.5e-31 107.3 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMD67091.1 - 1.3e-06 28.4 0.0 2.9e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhyH PF05721.8 EMD67092.1 - 2.8e-06 27.5 0.1 7.9e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EMD67092.1 - 1.7e-05 23.5 0.0 0.35 9.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EMD67092.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 EMD67093.1 - 5.1e-20 71.4 25.0 5.1e-20 71.4 17.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD67093.1 - 1.8e-05 23.5 1.7 1.8e-05 23.5 1.2 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter NfeD PF01957.13 EMD67093.1 - 0.078 13.1 0.0 0.078 13.1 0.0 3.4 5 0 0 5 5 5 0 NfeD-like C-terminal, partner-binding DUF4191 PF13829.1 EMD67093.1 - 0.81 8.7 5.2 0.91 8.5 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) Fungal_trans PF04082.13 EMD67094.1 - 2e-14 53.1 0.0 4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67094.1 - 2.7e-08 33.5 8.0 5.4e-08 32.6 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EMD67094.1 - 0.76 9.3 5.5 1.7 8.2 3.8 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 FAD_binding_3 PF01494.14 EMD67095.1 - 2.3e-22 79.5 0.0 4.4e-22 78.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD67095.1 - 1.6e-06 27.2 0.3 0.00017 20.6 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD67095.1 - 1.4e-05 24.2 0.4 0.00013 21.0 0.1 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD67095.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD67095.1 - 0.00066 19.6 0.1 0.0019 18.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD67095.1 - 0.002 18.0 0.4 0.0035 17.2 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD67095.1 - 0.0021 16.6 0.9 0.0037 15.7 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EMD67095.1 - 0.0024 16.7 0.6 0.005 15.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMD67095.1 - 0.013 15.2 0.1 0.94 9.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EMD67095.1 - 0.022 14.4 0.3 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMD67095.1 - 0.041 12.7 0.5 0.06 12.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.12 EMD67095.1 - 0.045 14.1 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EMD67095.1 - 0.17 12.2 0.4 0.47 10.8 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD67095.1 - 0.18 10.8 1.3 0.27 10.2 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.20 EMD67097.1 - 4e-28 98.2 0.0 4.5e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67097.1 - 2.8e-08 33.1 0.0 2.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67097.1 - 0.00047 19.2 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD67097.1 - 0.0068 16.1 0.1 0.015 15.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD67097.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMD67097.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EMD67097.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 ACT_7 PF13840.1 EMD67099.1 - 3e-25 87.5 0.0 6.1e-17 60.9 0.0 2.4 2 0 0 2 2 2 2 ACT domain Myosin_tail_1 PF01576.14 EMD67100.1 - 7.9e-07 27.2 61.4 7.9e-07 27.2 42.5 2.8 1 1 1 2 2 2 1 Myosin tail Tropomyosin_1 PF12718.2 EMD67100.1 - 0.00038 20.3 37.0 0.00066 19.5 11.5 7.4 3 2 2 7 7 7 2 Tropomyosin like GAS PF13851.1 EMD67100.1 - 0.0031 16.7 3.3 0.0031 16.7 2.3 6.3 3 2 2 6 6 6 5 Growth-arrest specific micro-tubule binding DUF1192 PF06698.6 EMD67100.1 - 0.96 9.3 36.0 4.6 7.1 0.1 8.7 6 2 1 7 7 7 0 Protein of unknown function (DUF1192) WEMBL PF05701.6 EMD67100.1 - 3.8 5.8 110.3 0.0069 14.9 7.4 4.3 1 1 3 4 4 4 0 Weak chloroplast movement under blue light GRP PF07172.6 EMD67101.1 - 0.46 10.9 12.0 0.093 13.2 6.1 1.5 2 0 0 2 2 2 0 Glycine rich protein family Nop10p PF04135.7 EMD67102.1 - 9.6e-19 66.8 0.4 1.2e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family AMP-binding PF00501.23 EMD67103.1 - 5.7e-48 163.3 0.0 8.4e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD67103.1 - 0.0046 17.8 0.0 0.0081 17.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M28 PF04389.12 EMD67106.1 - 4.2e-07 29.8 0.6 0.2 11.3 0.0 3.2 1 1 2 3 3 3 3 Peptidase family M28 PA PF02225.17 EMD67106.1 - 7.2e-06 25.6 0.1 2.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 PA domain CorA PF01544.13 EMD67109.1 - 1.7e-05 23.9 9.2 4.2e-05 22.7 6.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SieB PF14163.1 EMD67109.1 - 0.18 11.3 3.2 0.34 10.4 2.2 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B FixQ PF05545.6 EMD67109.1 - 0.33 10.6 5.1 1.2 8.8 3.5 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ricin_B_lectin PF00652.17 EMD67110.1 - 5.1e-09 36.2 0.0 1.4e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EMD67110.1 - 9.1e-08 32.4 0.0 1.2e-05 25.5 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF2529 PF10740.4 EMD67110.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) MFS_1 PF07690.11 EMD67111.1 - 7.2e-43 146.6 44.5 7e-40 136.8 30.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 EMD67112.1 - 1e-29 103.7 0.0 5.3e-29 101.4 0.0 1.9 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EMD67112.1 - 3.6e-09 36.9 0.0 1.1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain adh_short PF00106.20 EMD67113.1 - 7.9e-26 90.9 0.1 1.7e-25 89.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67113.1 - 1.1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD67113.1 - 5.5e-11 42.6 0.0 8.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD67113.1 - 5.5e-07 29.2 0.0 8.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD67113.1 - 0.0011 18.9 0.1 0.005 16.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMD67113.1 - 0.0044 15.9 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Parvo_NS1 PF01057.12 EMD67113.1 - 0.053 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HET PF06985.6 EMD67114.1 - 7.7e-33 113.5 0.1 1.1e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 EMD67114.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PAS_9 PF13426.1 EMD67116.1 - 0.067 13.5 0.1 9.6 6.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain DHHA2 PF02833.9 EMD67119.1 - 1.3e-28 99.7 0.0 2.4e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EMD67119.1 - 4.6e-10 39.3 0.0 2.2e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 DHH family Abhydrolase_2 PF02230.11 EMD67120.1 - 9.9e-22 77.4 0.0 1.2e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMD67120.1 - 1.5e-07 31.5 0.0 5.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD67120.1 - 1.7e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMD67120.1 - 0.0004 19.7 0.0 0.00052 19.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMD67120.1 - 0.011 15.2 0.2 0.15 11.6 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold EXS PF03124.9 EMD67121.1 - 2.5e-77 260.2 13.7 4e-69 233.2 3.6 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 EMD67121.1 - 3.2e-55 187.8 1.4 3.2e-55 187.8 1.0 2.5 3 0 0 3 3 3 1 SPX domain DUF3759 PF12585.3 EMD67121.1 - 1.1e-37 127.8 8.5 2.5e-37 126.6 5.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) MFS_1 PF07690.11 EMD67122.1 - 4.6e-32 111.0 46.4 1.7e-31 109.2 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD67122.1 - 2.3e-10 39.6 3.4 2.3e-10 39.6 2.4 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD67122.1 - 1.3e-05 23.8 0.6 1.3e-05 23.8 0.4 3.3 2 1 0 3 3 3 2 MFS/sugar transport protein His_Phos_1 PF00300.17 EMD67125.1 - 8.9e-18 64.8 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CDV3 PF15359.1 EMD67125.1 - 0.54 10.3 3.1 5.9 6.9 0.3 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 GalKase_gal_bdg PF10509.4 EMD67126.1 - 0.15 11.3 0.1 0.56 9.5 0.0 2.0 1 0 0 1 1 1 0 Galactokinase galactose-binding signature APC8 PF04049.8 EMD67127.1 - 1.1e-50 171.0 0.0 2.2e-50 170.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EMD67127.1 - 4.4e-23 79.8 5.7 0.0009 18.7 0.3 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMD67127.1 - 1.6e-21 75.6 10.3 2.3e-06 27.1 0.0 6.8 5 1 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 EMD67127.1 - 6.9e-13 47.4 18.6 0.23 11.4 0.9 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67127.1 - 3.1e-12 45.3 5.1 0.017 14.8 0.0 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67127.1 - 8.4e-12 44.6 15.5 0.036 14.6 0.0 8.5 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67127.1 - 9.3e-11 42.1 15.0 9.4e-05 22.9 0.3 6.1 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67127.1 - 1.8e-07 31.3 7.9 0.06 13.6 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67127.1 - 2.4e-07 30.6 17.8 0.0068 16.3 0.7 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD67127.1 - 7.7e-07 29.1 6.0 0.79 9.9 0.1 5.9 4 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMD67127.1 - 9.4e-07 28.5 3.1 2.1 8.7 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD67127.1 - 2.3e-06 27.6 17.5 0.18 12.2 0.4 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMD67127.1 - 6.7e-05 22.6 2.9 9.9 6.0 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMD67127.1 - 0.0016 17.5 1.3 0.0016 17.5 0.9 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD67127.1 - 0.0065 16.1 9.7 6.8 6.7 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMD67127.1 - 0.05 13.4 0.2 17 5.3 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat polyprenyl_synt PF00348.12 EMD67128.1 - 1.5e-77 259.9 0.0 1.7e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase PfkB PF00294.19 EMD67129.1 - 3.2e-52 177.5 5.2 3.8e-52 177.2 3.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_7 PF00840.15 EMD67130.1 - 6.2e-194 644.3 17.8 7.1e-194 644.1 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4506 PF14958.1 EMD67130.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Phytase PF02333.10 EMD67131.1 - 5.7e-60 203.0 2.9 1.1e-59 202.1 1.8 1.5 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 EMD67131.1 - 3.4e-07 30.3 27.5 0.00026 21.0 9.1 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_alliinase PF04863.8 EMD67131.1 - 1.9 8.5 16.8 1.2 9.1 0.7 3.2 2 1 0 2 2 2 0 Alliinase EGF-like domain TGT PF01702.13 EMD67132.1 - 1.2e-35 122.9 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pyr_redox_3 PF13738.1 EMD67133.1 - 9.3e-15 55.2 0.0 2.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD67133.1 - 1.7e-10 39.7 0.0 4.2e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD67133.1 - 5e-07 28.9 0.0 0.0011 18.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD67133.1 - 5.3e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD67133.1 - 2.7e-06 27.4 0.0 4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD67133.1 - 0.00014 21.6 0.2 0.014 15.1 0.2 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMD67133.1 - 0.0012 17.9 0.0 0.005 15.8 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EMD67133.1 - 0.0093 14.9 0.0 0.15 10.9 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMD67133.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD67133.1 - 0.15 10.5 0.2 1.5 7.1 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein GDI PF00996.13 EMD67133.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor F-box-like PF12937.2 EMD67135.1 - 2.5e-06 27.0 0.0 7.6e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD67135.1 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Dicer_dimer PF03368.9 EMD67136.1 - 0.031 14.0 0.1 0.044 13.5 0.1 1.3 1 1 0 1 1 1 0 Dicer dimerisation domain DUF3129 PF11327.3 EMD67137.1 - 3.4e-53 180.2 7.0 3.4e-53 180.2 4.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) NPCC PF08058.6 EMD67139.1 - 1.5e-28 99.4 0.0 2.9e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 EMD67140.1 - 2e-15 56.1 0.2 1.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Transp_cyt_pur PF02133.10 EMD67141.1 - 1.2e-99 333.8 47.1 1.4e-99 333.6 32.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adap_comp_sub PF00928.16 EMD67143.1 - 1.1e-90 303.3 0.0 1.3e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMD67143.1 - 2.3e-09 37.1 0.3 3.7e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_2 PF13639.1 EMD67144.1 - 3e-08 33.3 7.6 8.7e-08 31.8 5.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD67144.1 - 1e-06 28.7 3.5 1e-06 28.7 2.4 2.5 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMD67144.1 - 7.7e-05 22.3 2.1 0.00038 20.1 1.4 2.3 1 0 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.16 EMD67144.1 - 0.0001 22.0 1.0 0.00039 20.2 0.7 2.0 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4_3 PF13920.1 EMD67144.1 - 0.00021 20.9 0.8 0.00021 20.9 0.6 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD67144.1 - 0.00025 20.6 4.5 0.0007 19.2 3.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD67144.1 - 0.00092 19.1 5.0 0.00092 19.1 3.5 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD67144.1 - 0.01 15.5 8.2 0.2 11.4 6.2 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-Apc11 PF12861.2 EMD67144.1 - 0.047 13.5 4.5 0.16 11.8 3.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMD67144.1 - 0.094 12.6 0.5 0.094 12.6 0.3 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING MIS13 PF08202.6 EMD67144.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF892 PF05974.7 EMD67144.1 - 0.43 10.3 3.1 3.1 7.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF892) zf-RING_4 PF14570.1 EMD67144.1 - 0.84 9.2 5.6 4.3 7.0 0.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EMD67144.1 - 1.5 8.8 5.4 7 6.7 3.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PP2C PF00481.16 EMD67145.1 - 1.2e-36 126.4 0.2 1.7e-36 125.9 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMD67145.1 - 3.5e-05 23.2 2.2 0.05 12.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EMD67145.1 - 8.1e-05 22.4 0.4 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) NMO PF03060.10 EMD67148.1 - 1.7e-63 214.8 0.5 3.7e-63 213.6 0.3 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMD67148.1 - 2e-10 40.1 0.0 0.00049 19.1 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMD67148.1 - 0.00062 18.7 0.2 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.6 EMD67148.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) adh_short PF00106.20 EMD67149.1 - 2.4e-25 89.3 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67149.1 - 5.9e-16 58.9 0.0 6.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMD67149.1 - 1.6e-05 24.1 0.0 0.0017 17.5 0.0 2.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EMD67149.1 - 3.4e-05 23.5 0.0 6.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD67149.1 - 0.00082 19.4 0.0 0.0018 18.2 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMD67149.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.10 EMD67149.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 EMD67150.1 - 5.1e-36 124.1 22.8 1.2e-35 122.8 15.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 EMD67150.1 - 0.0048 16.8 0.9 0.0048 16.8 0.6 1.8 2 0 0 2 2 2 1 Stage V sporulation protein AB TauD PF02668.11 EMD67152.1 - 2.1e-13 50.5 0.0 6.8e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_2 PF00891.13 EMD67153.1 - 1.2e-24 86.8 0.0 1.5e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMD67153.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD67153.1 - 0.024 15.0 0.0 0.048 14.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMD67153.1 - 0.048 13.2 0.0 0.098 12.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMD67153.1 - 0.14 12.6 0.0 0.57 10.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Dimerisation PF08100.6 EMD67154.1 - 0.00043 20.0 0.0 0.00092 18.9 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.2 EMD67154.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 0 MarR family TetR_N PF00440.18 EMD67154.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR PF01047.17 EMD67154.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 MarR family Zn_clus PF00172.13 EMD67155.1 - 1.3e-10 40.9 13.0 4.1e-10 39.3 9.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EMD67156.1 - 4.8e-19 68.7 0.6 1.1e-18 67.5 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD67156.1 - 4.8e-16 58.3 0.0 6.1e-15 54.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD67156.1 - 6.7e-12 44.8 1.4 6.9e-11 41.5 1.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMD67156.1 - 4.3e-09 36.6 2.7 1.1e-08 35.3 1.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD67156.1 - 1.2e-08 34.2 0.0 1.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMD67156.1 - 6.4e-07 28.8 1.0 1.5e-06 27.6 0.5 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMD67156.1 - 1.5e-06 28.2 2.3 1e-05 25.4 1.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67156.1 - 0.0039 16.8 3.1 0.089 12.4 2.1 2.3 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EMD67156.1 - 0.071 11.9 0.3 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Dicty_REP PF05086.7 EMD67157.1 - 0.21 9.2 1.7 0.23 9.1 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 EMD67157.1 - 0.56 9.9 6.7 0.93 9.1 4.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus adh_short PF00106.20 EMD67158.1 - 5.2e-17 62.2 3.6 8.4e-17 61.5 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67158.1 - 5.2e-14 52.6 0.0 9.1e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67158.1 - 5.6e-07 29.3 0.4 7.3e-07 29.0 0.3 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMD67159.1 - 5.7e-44 150.1 0.0 6.9e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD67159.1 - 3.1e-12 46.8 0.1 7e-12 45.7 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EMD67159.1 - 2.3e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EMD67159.1 - 1.8e-06 27.9 0.3 2.7e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMD67159.1 - 7.6e-06 25.5 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD67159.1 - 1.2e-05 24.2 0.0 1.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMD67159.1 - 0.00011 21.9 0.1 0.00017 21.3 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMD67159.1 - 0.00085 19.7 0.1 0.0018 18.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TauD PF02668.11 EMD67160.1 - 5.7e-40 137.6 0.0 7.3e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4483 PF14825.1 EMD67160.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) UbiA PF01040.13 EMD67161.1 - 1.2e-25 90.1 18.0 1.7e-25 89.7 12.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Pyr_redox_3 PF13738.1 EMD67162.1 - 1.2e-22 80.9 0.0 3.2e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD67162.1 - 1.9e-06 27.0 0.0 4.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD67162.1 - 3.1e-05 23.8 0.4 7.7e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMD67162.1 - 0.0047 16.0 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMD67162.1 - 0.022 14.8 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EMD67162.1 - 0.032 12.4 0.0 0.08 11.1 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EMD67162.1 - 0.055 13.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EMD67162.1 - 0.089 11.6 1.7 0.11 11.3 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMD67162.1 - 0.13 12.5 0.8 21 5.4 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Ribosomal_L20 PF00453.13 EMD67164.1 - 0.032 14.1 3.7 0.042 13.7 2.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2951 PF11166.3 EMD67164.1 - 0.27 11.1 1.6 0.3 10.9 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) HemY_N PF07219.8 EMD67164.1 - 0.77 9.3 4.3 0.56 9.7 1.4 1.7 1 1 1 2 2 2 0 HemY protein N-terminus Helicase_C_3 PF13625.1 EMD67165.1 - 2.2e-25 88.9 0.1 2.8e-24 85.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD67165.1 - 5.7e-15 55.6 0.0 1.8e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMD67165.1 - 2e-12 46.7 0.1 2e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMD67165.1 - 9.6e-10 37.7 0.1 1.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.1 EMD67165.1 - 0.018 14.3 0.0 0.079 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Hid1 PF12722.2 EMD67166.1 - 9.1e-270 897.2 0.0 4.2e-269 895.0 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EMD67166.1 - 9.5e-90 301.6 0.0 1.3e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein GHL1-3 PF11308.3 EMD67166.1 - 0.21 10.8 0.0 0.46 9.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 EHN PF06441.7 EMD67167.1 - 7.4e-30 103.1 0.1 1.2e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMD67167.1 - 3.3e-07 30.4 0.2 3.3e-07 30.4 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD67167.1 - 4.1e-06 26.5 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SAM_decarbox PF01536.11 EMD67168.1 - 3.1e-83 279.2 0.0 9e-59 198.7 0.0 3.6 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase Flu_B_NS1 PF02942.9 EMD67168.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Metallophos PF00149.23 EMD67170.1 - 1.8e-41 141.7 1.1 2.7e-41 141.1 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chitin_bind_3 PF03067.10 EMD67171.1 - 4.7e-06 26.9 0.1 7.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 EMD67171.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.3 EMD67172.1 - 1.7e-40 137.0 15.7 4.6e-24 84.3 0.4 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Peptidase_M50 PF02163.17 EMD67172.1 - 0.03 13.2 0.2 0.073 12.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase family M50 RmlD_sub_bind PF04321.12 EMD67173.1 - 3.3e-51 173.8 0.0 4.1e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMD67173.1 - 2.4e-23 82.8 0.0 3.3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMD67173.1 - 4.3e-10 38.9 0.0 1.3e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMD67173.1 - 1.9e-09 36.8 0.4 1.4e-07 30.7 0.1 2.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMD67173.1 - 2.6e-09 36.2 0.0 1.5e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD67173.1 - 6.9e-08 32.7 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMD67173.1 - 0.0018 18.1 0.3 0.071 13.0 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NUDIX_2 PF13869.1 EMD67174.1 - 9.1e-81 269.6 0.0 1.1e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase GST_C PF00043.20 EMD67176.1 - 1.9e-09 37.4 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD67176.1 - 3.5e-07 30.3 0.1 6.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD67176.1 - 2.2e-05 24.5 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD67176.1 - 8e-05 22.4 0.4 0.00034 20.4 0.2 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD67176.1 - 0.00014 22.2 0.1 0.00029 21.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD67176.1 - 0.0002 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Toxin-deaminase PF14424.1 EMD67177.1 - 0.00024 21.1 1.4 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases DUF4349 PF14257.1 EMD67177.1 - 0.053 12.7 1.1 0.083 12.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DYW_deaminase PF14432.1 EMD67177.1 - 0.096 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Apt1 PF10351.4 EMD67178.1 - 0.0078 15.1 0.2 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain MscS_porin PF12795.2 EMD67178.1 - 0.012 14.9 4.1 1.9 7.7 3.8 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 EMD67178.1 - 0.2 11.4 2.1 7 6.4 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) GIY-YIG PF01541.19 EMD67179.1 - 4.6e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EMD67179.1 - 0.00011 22.0 2.4 0.00024 20.9 1.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 EMD67179.1 - 0.0013 18.3 3.0 0.0027 17.3 2.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMD67179.1 - 0.0019 18.2 2.1 0.0047 17.0 1.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_2 PF13639.1 EMD67179.1 - 0.014 15.2 4.7 0.025 14.3 3.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 EMD67179.1 - 0.017 15.1 2.2 0.032 14.2 1.5 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.2 EMD67179.1 - 0.58 10.2 3.3 1.2 9.2 2.3 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EMD67179.1 - 0.76 9.5 4.2 0.42 10.3 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EMD67179.1 - 1.1 9.2 5.0 5.3 7.1 3.5 2.2 1 1 0 1 1 1 0 RING-like domain PLU-1 PF08429.6 EMD67180.1 - 1e-98 330.3 10.1 1.2e-95 320.2 6.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EMD67180.1 - 9.6e-45 151.4 1.1 2.2e-44 150.3 0.1 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EMD67180.1 - 6.1e-28 96.5 0.1 3.9e-27 93.9 0.1 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EMD67180.1 - 2.3e-16 59.2 28.9 1.2e-08 34.5 5.9 3.0 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EMD67180.1 - 4.9e-16 57.9 1.1 1.1e-15 56.8 0.8 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EMD67180.1 - 1.5e-14 53.7 5.6 3.9e-14 52.4 3.9 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger C1_1 PF00130.17 EMD67180.1 - 0.099 12.3 9.3 0.87 9.3 2.3 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) 60KD_IMP PF02096.15 EMD67181.1 - 1.1e-24 87.1 0.1 1.6e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 EMD67182.1 - 1.7e-28 98.1 0.0 2.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EMD67183.1 - 5.6e-30 103.4 0.0 9.7e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EMD67183.1 - 1.1e-15 57.3 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMD67183.1 - 1.8e-10 40.1 1.9 3.2e-10 39.3 1.3 1.4 1 0 0 1 1 1 1 UBA-like domain HTH_IclR PF09339.5 EMD67183.1 - 0.03 13.8 0.2 0.06 12.9 0.2 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF3405 PF11885.3 EMD67184.1 - 4.5e-157 523.2 14.6 1.3e-156 521.7 10.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1929 PF09118.6 EMD67185.1 - 6.1e-29 100.0 0.4 1.3e-28 98.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.21 EMD67185.1 - 5.9e-16 57.9 1.7 2.8e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.1 EMD67185.1 - 3.4e-15 55.5 3.5 2.9e-06 26.9 0.1 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EMD67185.1 - 1.3e-13 50.1 0.8 1.4e-07 30.9 0.1 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EMD67185.1 - 7.2e-13 48.1 5.5 0.00022 21.2 0.0 5.5 3 1 2 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EMD67185.1 - 5.3e-12 44.9 0.1 5.5e-06 25.9 0.0 5.0 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 EMD67185.1 - 1.4e-08 34.6 2.0 0.095 12.8 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain PAN_4 PF14295.1 EMD67185.1 - 7.3e-06 25.5 9.0 0.0024 17.5 0.9 2.7 2 0 0 2 2 2 2 PAN domain Glyoxal_oxid_N PF07250.6 EMD67185.1 - 1.2e-05 24.4 0.1 0.13 11.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus PAN_3 PF08277.7 EMD67185.1 - 0.015 14.9 4.6 0.91 9.1 0.2 2.5 2 0 0 2 2 2 0 PAN-like domain Fungal_trans PF04082.13 EMD67186.1 - 5.2e-12 45.1 0.1 9.4e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67186.1 - 7e-09 35.4 8.0 1.6e-08 34.3 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pilt PF15453.1 EMD67186.1 - 0.095 12.3 2.1 0.14 11.7 1.5 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions GATase_5 PF13507.1 EMD67187.1 - 4.4e-98 327.2 0.0 6.8e-98 326.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EMD67187.1 - 1.1e-46 158.5 0.1 1.6e-22 80.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMD67187.1 - 6.8e-26 90.3 0.2 4.2e-24 84.6 0.0 3.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain OCD_Mu_crystall PF02423.10 EMD67187.1 - 2.8e-15 55.8 0.0 1.4e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMD67187.1 - 1.7e-08 34.6 0.0 6.1e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMD67187.1 - 0.0033 16.4 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 5_3_exonuc_N PF02739.11 EMD67187.1 - 0.3 10.4 0.0 0.59 9.4 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF2338 PF10100.4 EMD67187.1 - 0.41 8.9 0.1 2.1 6.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2338) FAD_binding_4 PF01565.18 EMD67190.1 - 5.7e-24 84.1 0.9 1.4e-23 82.9 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD67190.1 - 7.2e-05 22.6 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like PufQ PF05398.6 EMD67191.1 - 2.8 8.0 6.4 15 5.7 0.3 3.4 3 0 0 3 3 3 0 PufQ cytochrome subunit adh_short PF00106.20 EMD67194.1 - 3.4e-25 88.8 0.2 4.8e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67194.1 - 1.7e-09 37.8 0.3 2.4e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67194.1 - 6.6e-08 32.4 0.1 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMD67194.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EMD67194.1 - 0.014 15.5 0.1 0.036 14.1 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 EMD67196.1 - 2.1e-57 194.4 4.8 2.7e-57 194.1 3.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67196.1 - 2.3e-06 27.3 5.1 4.4e-06 26.5 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob_synth_C PF06463.8 EMD67196.1 - 0.03 14.0 2.2 0.044 13.4 0.2 2.3 3 0 0 3 3 3 0 Molybdenum Cofactor Synthesis C CoA_transf_3 PF02515.12 EMD67197.1 - 3.8e-50 169.7 0.0 5.2e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III NAAA-beta PF15508.1 EMD67198.1 - 5.7e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Thiol_cytolysin PF01289.14 EMD67198.1 - 0.0086 14.4 0.0 0.013 13.9 0.0 1.1 1 0 0 1 1 1 1 Thiol-activated cytolysin HTH_23 PF13384.1 EMD67198.1 - 0.03 13.9 0.1 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_L27 PF01016.14 EMD67199.1 - 1.5e-26 92.0 0.1 2.8e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal L27 protein RRN9 PF10680.4 EMD67199.1 - 0.068 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Glyco_hydro_56 PF01630.13 EMD67199.1 - 0.094 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Hyaluronidase Dynamin_M PF01031.15 EMD67200.1 - 4.4e-106 353.9 0.3 1e-105 352.7 0.2 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EMD67200.1 - 9.1e-57 191.5 0.1 2.2e-56 190.2 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMD67200.1 - 8.5e-29 99.2 5.0 2e-28 98.0 3.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMD67200.1 - 3e-05 23.9 0.0 0.00026 20.9 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD67200.1 - 0.026 15.0 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 EMD67201.1 - 7e-115 381.9 0.0 1e-114 381.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMD67201.1 - 4e-20 72.3 0.5 1.3e-19 70.7 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMD67201.1 - 1.6e-15 57.0 1.3 3.2e-15 56.0 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF2324 PF10086.4 EMD67202.1 - 0.2 10.8 9.4 0.13 11.3 1.8 2.4 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) zf-CCHC PF00098.18 EMD67204.1 - 4.3e-06 26.3 1.9 6.6e-06 25.8 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle TFIIF_alpha PF05793.7 EMD67204.1 - 0.00094 17.6 11.7 0.0011 17.4 8.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CCHC_3 PF13917.1 EMD67204.1 - 0.04 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.7 EMD67204.1 - 0.11 12.2 11.4 0.17 11.6 7.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 EMD67204.1 - 0.88 9.3 10.8 0.11 12.3 0.6 2.3 1 1 1 2 2 2 0 RXT2-like, N-terminal EthD PF07110.6 EMD67205.1 - 7.9e-20 71.5 0.4 1e-19 71.2 0.2 1.2 1 0 0 1 1 1 1 EthD domain Peptidase_M16 PF00675.15 EMD67206.1 - 1.9e-32 112.0 1.4 3.2e-31 108.0 0.9 2.6 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMD67206.1 - 4e-29 101.5 0.2 2.9e-21 75.9 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain FLILHELTA PF10306.4 EMD67207.1 - 5.3e-28 96.8 0.0 8e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EMD67207.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) UPF0047 PF01894.12 EMD67209.1 - 3.2e-41 139.8 0.1 5.1e-41 139.1 0.0 1.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 EMD67210.1 - 5.3e-15 54.9 1.9 8.2e-15 54.3 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain AAL_decarboxy PF03306.8 EMD67211.1 - 4.6e-28 97.7 0.0 4.6e-13 48.7 0.0 2.0 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase HET PF06985.6 EMD67212.1 - 4.9e-06 26.7 0.1 1e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M18 PF02127.10 EMD67213.1 - 2.8e-128 428.1 0.0 3.3e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) IPP-2 PF04979.9 EMD67214.1 - 3.4e-10 40.2 16.3 1e-06 29.0 3.4 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) IF4E PF01652.13 EMD67215.1 - 1.2e-50 171.3 0.1 1.2e-50 171.3 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EMD67216.1 - 8.4e-26 90.9 0.0 2.3e-25 89.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2 PF06094.7 EMD67217.1 - 1.7e-15 57.3 0.0 2.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family PQ-loop PF04193.9 EMD67218.1 - 2e-20 72.0 1.4 8.5e-13 47.6 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF2809 PF10990.3 EMD67218.1 - 0.86 10.0 5.0 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) Glyco_hydro_43 PF04616.9 EMD67219.1 - 3.5e-61 206.7 11.3 4.7e-54 183.4 0.9 3.0 2 1 0 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMD67219.1 - 1e-10 41.4 1.2 4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Alk_phosphatase PF00245.15 EMD67220.1 - 5.7e-80 269.0 0.0 7.1e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase MNHE PF01899.11 EMD67220.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Spc97_Spc98 PF04130.8 EMD67223.1 - 8.2e-68 229.0 7.1 1e-67 228.7 4.9 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EMD67223.1 - 0.00014 20.1 0.2 0.25 9.3 0.0 2.3 2 0 0 2 2 2 2 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 EMD67224.1 - 7e-134 445.9 10.0 8.3e-134 445.7 6.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Neuregulin PF02158.10 EMD67224.1 - 0.054 12.2 0.1 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Neuregulin family DUF3281 PF11685.3 EMD67224.1 - 0.097 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) Pkinase PF00069.20 EMD67225.1 - 7.2e-28 97.4 0.1 1.2e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 EMD67225.1 - 6.7e-21 74.9 0.0 3e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pox_ser-thr_kin PF05445.6 EMD67225.1 - 0.084 11.6 0.0 0.26 10.0 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF4560 PF15118.1 EMD67225.1 - 0.21 11.3 0.3 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) Pkinase PF00069.20 EMD67227.1 - 3.8e-23 81.9 0.0 6.6e-22 77.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67227.1 - 7.7e-11 41.5 0.0 2.1e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_31 PF01055.21 EMD67228.1 - 2.7e-151 504.3 6.1 3.6e-151 503.9 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD67228.1 - 6.6e-24 83.5 1.1 1.4e-23 82.4 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 EMD67229.1 - 1.3e-55 186.9 0.0 1.4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Amidase PF01425.16 EMD67231.1 - 8e-81 272.1 0.0 9.8e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.17 EMD67232.1 - 7.8e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps54 PF07928.7 EMD67233.1 - 6.6e-41 139.6 0.6 1.4e-40 138.5 0.2 1.8 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EMD67233.1 - 0.00012 21.1 0.6 0.00059 18.8 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EMD67233.1 - 0.0041 16.7 0.2 1.5 8.4 0.0 3.1 3 0 0 3 3 3 2 Sec8 exocyst complex component specific domain NACHT PF05729.7 EMD67235.1 - 0.00079 19.1 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Cadherin_2 PF08266.7 EMD67235.1 - 0.0071 15.8 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 2 Cadherin-like DUF4145 PF13643.1 EMD67235.1 - 0.1 12.4 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) Ank_2 PF12796.2 EMD67236.1 - 1.3e-22 79.9 0.0 2.9e-16 59.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD67236.1 - 6.3e-21 74.3 0.1 1.5e-07 31.7 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMD67236.1 - 3.4e-19 67.5 0.4 1.4e-05 24.6 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EMD67236.1 - 3.1e-14 51.6 0.1 5.8e-06 26.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMD67236.1 - 9.1e-14 51.1 0.1 0.00011 22.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Terpene_synth_C PF03936.11 EMD67237.1 - 1.1e-07 31.3 0.4 1.8e-07 30.6 0.3 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain NOB1_Zn_bind PF08772.6 EMD67238.1 - 5.2e-27 93.4 3.1 5.2e-27 93.4 2.1 2.3 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EMD67238.1 - 0.0018 17.7 1.2 0.0049 16.3 0.9 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain RecR PF02132.10 EMD67238.1 - 0.2 11.1 2.1 0.83 9.1 1.5 2.0 1 1 1 2 2 2 0 RecR protein DUF2939 PF11159.3 EMD67238.1 - 1.2 9.4 9.3 6 7.1 1.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) DUF2321 PF10083.4 EMD67238.1 - 4.8 6.6 8.2 1.8 8.0 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Tim17 PF02466.14 EMD67239.1 - 3.6e-54 182.2 11.4 4.4e-53 178.7 7.9 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.1 EMD67240.1 - 1e-24 87.5 20.5 1e-24 87.5 14.2 4.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4048) Pkinase PF00069.20 EMD67242.1 - 3e-68 229.7 0.0 4.3e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67242.1 - 1e-45 155.8 0.0 1.5e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67242.1 - 2.9e-05 23.1 0.0 0.00063 18.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD67242.1 - 0.00014 21.6 0.0 0.5 10.0 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EMD67242.1 - 0.048 12.7 0.5 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_Phos_2 PF00328.17 EMD67243.1 - 4.7e-41 141.2 0.0 6.4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2530 PF10745.4 EMD67244.1 - 0.27 11.2 2.1 0.81 9.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) adh_short PF00106.20 EMD67245.1 - 1.1e-31 110.0 0.8 1.7e-31 109.3 0.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67245.1 - 2.9e-18 66.5 0.0 3.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67245.1 - 1.2e-14 54.3 0.2 1.7e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD67245.1 - 4.8e-05 22.9 0.1 0.0001 21.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dak1_2 PF13684.1 EMD67245.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Pkinase PF00069.20 EMD67246.1 - 2.6e-07 30.0 0.0 3.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67246.1 - 5.3e-07 28.9 0.0 6.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EMD67248.1 - 2.8e-29 99.9 18.1 1.2e-07 31.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMD67248.1 - 0.0004 18.6 2.0 0.065 11.3 0.0 3.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.16 EMD67248.1 - 0.039 13.4 0.1 1.7 8.2 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.1 EMD67248.1 - 0.99 9.7 15.4 2 8.8 0.1 4.7 5 1 0 5 5 5 0 PQQ-like domain Voldacs PF03517.8 EMD67249.1 - 1.1e-24 86.7 0.1 2e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling zf-RING_3 PF14369.1 EMD67250.1 - 0.017 15.1 0.3 0.041 13.8 0.2 1.6 1 0 0 1 1 1 0 zinc-finger TMEM154 PF15102.1 EMD67250.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family MLANA PF14991.1 EMD67250.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Shisa PF13908.1 EMD67250.1 - 0.11 12.6 2.5 0.089 12.9 0.6 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_hydro_92 PF07971.7 EMD67251.1 - 2.1e-170 567.7 0.0 2.7e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 E1-E2_ATPase PF00122.15 EMD67255.1 - 2.7e-62 209.7 6.3 2.7e-62 209.7 4.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD67255.1 - 1.2e-31 109.6 1.4 1.2e-31 109.6 1.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD67255.1 - 2.5e-28 99.9 1.3 2.1e-26 93.6 0.9 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD67255.1 - 6.3e-18 64.0 0.0 3e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMD67255.1 - 5.3e-12 46.3 0.1 2.2e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD67255.1 - 7.1e-11 41.9 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMD67255.1 - 1.8e-06 27.6 0.9 8.6e-06 25.5 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.1 EMD67255.1 - 0.35 10.9 0.0 0.35 10.9 0.0 3.5 3 1 1 4 4 4 0 2TM domain DUF3650 PF12368.3 EMD67255.1 - 0.59 9.6 2.3 24 4.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Chromo PF00385.19 EMD67256.1 - 0.00019 21.0 2.3 0.00046 19.8 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UPF0029 PF01205.14 EMD67258.1 - 7.2e-35 119.0 0.0 1.1e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EMD67258.1 - 6.2e-09 35.7 0.0 9.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EMD67258.1 - 0.026 13.9 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Syntaxin-6_N PF09177.6 EMD67262.1 - 3e-24 85.2 3.1 3.9e-24 84.8 0.2 2.3 3 0 0 3 3 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EMD67262.1 - 4.7e-14 51.8 14.8 1.8e-13 49.9 1.3 3.3 3 0 0 3 3 3 2 SNARE domain Mer2 PF09074.5 EMD67262.1 - 0.0024 17.8 1.0 0.0043 16.9 0.7 1.3 1 0 0 1 1 1 1 Mer2 Laminin_II PF06009.7 EMD67262.1 - 0.005 16.5 0.8 0.63 9.7 0.2 2.3 2 0 0 2 2 2 1 Laminin Domain II PilJ PF13675.1 EMD67262.1 - 0.0085 16.4 2.2 0.054 13.8 1.5 2.2 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 EMD67262.1 - 0.017 14.7 2.9 0.017 14.7 2.0 2.7 3 0 0 3 3 2 0 IncA protein Prominin PF05478.6 EMD67262.1 - 0.018 12.5 0.1 0.023 12.2 0.0 1.1 1 0 0 1 1 1 0 Prominin Acyl-CoA_dh_C PF12806.2 EMD67262.1 - 0.046 13.5 0.1 3.7 7.4 0.0 2.9 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like WXG100 PF06013.7 EMD67262.1 - 0.048 13.6 2.8 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Snapin_Pallidin PF14712.1 EMD67262.1 - 0.071 13.4 1.2 3.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF883 PF05957.8 EMD67262.1 - 0.094 13.1 7.6 0.94 9.9 0.2 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TBPIP PF07106.8 EMD67262.1 - 0.15 11.5 4.2 0.065 12.7 0.9 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Halogen_Hydrol PF10112.4 EMD67262.1 - 0.16 11.3 0.7 0.31 10.4 0.1 1.9 2 0 0 2 2 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2077 PF09850.4 EMD67262.1 - 0.18 11.2 4.0 2.5 7.4 0.1 3.1 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) RRF PF01765.14 EMD67262.1 - 0.22 10.9 4.4 4 6.8 0.2 2.8 1 1 2 3 3 3 0 Ribosome recycling factor CK2S PF15011.1 EMD67262.1 - 0.24 11.2 3.8 1.4 8.6 0.0 2.9 2 1 1 3 3 3 0 Casein Kinase 2 substrate THOC7 PF05615.8 EMD67262.1 - 0.33 11.2 5.7 0.77 10.0 1.1 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF972 PF06156.8 EMD67262.1 - 0.34 11.2 6.0 1 9.7 1.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF972) OmpH PF03938.9 EMD67262.1 - 0.35 10.7 8.4 1.1 9.1 5.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YtxH PF12732.2 EMD67262.1 - 0.37 11.1 3.7 5.7 7.3 2.6 2.6 1 1 0 1 1 1 0 YtxH-like protein DUF3618 PF12277.3 EMD67262.1 - 0.51 10.4 5.7 24 5.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF1664 PF07889.7 EMD67262.1 - 0.56 9.9 3.7 11 5.8 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AKNA PF12443.3 EMD67262.1 - 0.62 10.0 4.2 1.6 8.7 0.1 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor Vps51 PF08700.6 EMD67262.1 - 0.79 9.5 3.9 15 5.4 0.1 3.0 3 0 0 3 3 3 0 Vps51/Vps67 Adaptin_binding PF10199.4 EMD67262.1 - 1.6 9.0 8.9 2.9 8.1 6.2 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 APG6 PF04111.7 EMD67262.1 - 3.4 6.6 8.1 0.41 9.6 1.4 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Methyltransf_32 PF13679.1 EMD67263.1 - 1.3e-19 70.3 4.0 1.2e-18 67.1 2.8 2.1 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_S41 PF03572.13 EMD67264.1 - 3.1e-08 33.2 0.0 6.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Asp PF00026.18 EMD67265.1 - 4.1e-08 32.8 0.0 5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EMD67265.1 - 1.7e-05 24.4 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4658 PF15555.1 EMD67267.1 - 0.4 10.5 2.8 0.34 10.7 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) Glyco_hydro_72 PF03198.9 EMD67268.1 - 1e-118 395.9 1.8 1.2e-118 395.7 1.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EMD67268.1 - 3.3e-06 26.2 0.0 4.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EMD67268.1 - 0.0024 17.1 4.1 0.0096 15.1 2.8 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SLH PF00395.15 EMD67268.1 - 0.11 12.2 0.5 6.8 6.5 0.4 2.7 1 1 0 1 1 1 0 S-layer homology domain SGS PF05002.10 EMD67269.1 - 1.1e-26 92.4 0.5 2.5e-26 91.2 0.4 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EMD67269.1 - 4.8e-18 65.4 1.1 6e-18 65.1 0.1 1.7 2 0 0 2 2 1 1 CS domain TPR_11 PF13414.1 EMD67269.1 - 1.7e-12 46.8 0.1 2.9e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMD67269.1 - 5.3e-09 35.3 0.7 9.2e-05 21.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD67269.1 - 1e-08 34.4 0.6 0.018 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67269.1 - 1e-07 32.3 1.2 0.00024 21.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67269.1 - 0.024 14.9 0.2 2.1 8.7 0.1 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67269.1 - 0.035 14.0 0.8 6.1 6.8 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67269.1 - 0.049 14.2 0.1 11 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2360 PF10152.4 EMD67269.1 - 0.054 13.7 0.7 0.054 13.7 0.5 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Apc3 PF12895.2 EMD67269.1 - 0.067 13.3 0.1 0.5 10.5 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EMD67269.1 - 0.069 12.9 0.1 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 EMD67269.1 - 0.12 12.5 0.1 27 5.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1996 PF09362.5 EMD67273.1 - 7e-81 271.3 0.2 9.8e-81 270.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Nucleo_LEF-12 PF06256.6 EMD67273.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein PQ-loop PF04193.9 EMD67276.1 - 6e-41 137.8 12.8 2.1e-20 71.9 3.2 2.9 2 0 0 2 2 2 2 PQ loop repeat DUF3784 PF12650.2 EMD67276.1 - 5.1 7.1 9.7 0.089 12.7 0.6 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3784) DUF962 PF06127.6 EMD67277.1 - 1.1e-24 86.1 0.4 1.6e-24 85.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Sugar_tr PF00083.19 EMD67278.1 - 5e-82 275.8 21.3 7.5e-82 275.2 14.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD67278.1 - 1.6e-14 53.4 40.1 9.3e-10 37.7 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 EMD67278.1 - 0.00088 18.2 0.1 0.0023 16.9 0.1 1.6 1 0 0 1 1 1 1 UAA transporter family Gtr1_RagA PF04670.7 EMD67279.1 - 3.6e-93 311.0 0.1 4.5e-93 310.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMD67279.1 - 5e-08 32.5 0.5 9.9e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EMD67279.1 - 2.8e-07 29.9 0.0 5.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMD67279.1 - 4.2e-07 30.4 0.0 9.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMD67279.1 - 4.1e-05 23.5 0.0 9.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD67279.1 - 0.00018 21.0 0.0 0.00055 19.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EMD67279.1 - 0.002 17.0 0.1 0.0035 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EMD67279.1 - 0.01 15.3 0.4 0.028 13.9 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EMD67279.1 - 0.018 15.3 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EMD67279.1 - 0.041 13.0 0.1 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMD67279.1 - 0.044 12.8 0.1 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EMD67279.1 - 0.13 12.3 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1688 PF07958.6 EMD67280.1 - 1e-182 607.3 0.0 1.2e-182 607.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_11 PF13414.1 EMD67281.1 - 2.1e-09 36.8 0.2 1.7e-08 33.9 0.0 2.5 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EMD67281.1 - 4.3e-05 22.9 0.6 1 9.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD67281.1 - 7.5e-05 22.3 0.5 16 5.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat DnaJ PF00226.26 EMD67281.1 - 0.0088 15.7 2.7 0.0096 15.6 0.1 2.4 3 0 0 3 3 3 1 DnaJ domain UBA PF00627.26 EMD67281.1 - 0.052 13.4 0.5 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Fungal_trans PF04082.13 EMD67283.1 - 2.4e-09 36.4 0.0 7e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67283.1 - 6.3e-05 22.7 10.7 0.00012 21.8 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.21 EMD67285.1 - 1.1e-08 34.7 5.9 2.6e-08 33.5 4.1 1.6 1 0 0 1 1 1 1 WW domain DUF4407 PF14362.1 EMD67285.1 - 2.5 6.9 5.5 3.1 6.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.2 EMD67286.1 - 5.5e-29 100.3 4.9 7.2e-18 64.7 0.7 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD67286.1 - 2e-19 68.3 1.9 3.1e-11 42.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD67286.1 - 9.2e-19 67.4 1.2 3.4e-14 52.8 0.1 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD67286.1 - 2e-15 56.4 3.1 1.7e-09 37.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67286.1 - 2.3e-15 55.1 0.7 7.1e-08 31.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Rad9_Rad53_bind PF08605.5 EMD67288.1 - 3.2e-14 52.8 0.0 5.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EMD67288.1 - 3.7e-08 33.4 0.0 1.1e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CAF1C_H4-bd PF12265.3 EMD67288.1 - 0.084 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Sdh_cyt PF01127.17 EMD67289.1 - 7.7e-24 83.8 3.7 9.6e-24 83.5 2.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit WD40 PF00400.27 EMD67290.1 - 9.2e-15 53.8 3.8 2.9e-05 23.7 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Prenyltrans_1 PF13243.1 EMD67291.1 - 1.3e-26 92.6 0.2 1.8e-17 63.2 0.1 5.6 4 2 2 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 EMD67291.1 - 1.1e-25 88.8 7.1 7e-08 31.8 0.0 4.8 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMD67291.1 - 3.4e-23 82.2 2.5 1.3e-09 38.4 0.0 5.6 4 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EMD67291.1 - 9e-06 25.0 1.7 5.8 5.9 0.0 5.6 4 2 1 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EMD67291.1 - 0.0038 16.4 0.0 0.076 12.2 0.0 2.8 2 1 0 3 3 3 1 A-macroglobulin complement component Chromadorea_ALT PF05535.7 EMD67291.1 - 0.13 12.3 0.1 0.13 12.3 0.0 2.2 3 0 0 3 3 3 0 Chromadorea ALT protein DUF1295 PF06966.7 EMD67294.1 - 3.6e-12 46.0 0.0 4.6e-12 45.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EMD67294.1 - 0.0081 15.9 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_ligase_A_M PF01068.16 EMD67295.1 - 4e-28 98.1 0.0 9.2e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD67295.1 - 1.6e-11 44.3 0.0 3.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus Glyco_hydro_42 PF02449.10 EMD67296.1 - 1.3e-12 47.5 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EMD67296.1 - 1.6e-07 30.9 0.0 1.7e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EMD67296.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 SPC22 PF04573.7 EMD67297.1 - 6.7e-33 113.3 0.0 2.3e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit YqzM PF14141.1 EMD67297.1 - 0.29 10.9 1.7 0.48 10.2 1.2 1.3 1 0 0 1 1 1 0 YqzM-like protein Pyr_redox_3 PF13738.1 EMD67298.1 - 2.7e-29 102.7 0.0 9.4e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD67298.1 - 0.00039 20.3 0.1 0.0025 17.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMD67298.1 - 0.0017 18.4 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMD67298.1 - 0.0081 15.9 0.2 0.42 10.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD67298.1 - 0.0082 16.0 0.0 8.6 6.1 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD67298.1 - 0.009 14.9 0.0 0.045 12.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EMD67298.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribonucleas_3_3 PF14622.1 EMD67299.1 - 2.9e-15 56.3 0.0 3.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD67299.1 - 4e-09 36.9 0.0 1e-08 35.5 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain DUF465 PF04325.8 EMD67300.1 - 0.093 12.4 1.5 0.14 11.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Lge1 PF11488.3 EMD67300.1 - 0.1 12.8 0.7 0.13 12.4 0.5 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ADH_N PF08240.7 EMD67301.1 - 0.00024 20.8 0.0 0.0009 18.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ParA PF10609.4 EMD67302.1 - 3e-35 119.9 0.5 5.7e-35 119.0 0.1 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMD67302.1 - 2.9e-16 59.4 0.0 4.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EMD67302.1 - 7.6e-07 28.4 0.0 4.3e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EMD67302.1 - 2e-06 27.0 0.3 3.3e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EMD67302.1 - 3.2e-06 27.1 0.1 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EMD67302.1 - 9.7e-05 22.0 0.7 0.028 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EMD67302.1 - 0.0014 17.4 0.1 0.0021 16.8 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EMD67302.1 - 0.0042 16.5 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EMD67302.1 - 0.013 14.8 0.1 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 EMD67302.1 - 0.016 14.4 0.1 0.035 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EMD67302.1 - 0.05 13.2 0.1 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Abi_HHR PF07815.9 EMD67303.1 - 0.0038 17.3 2.4 0.3 11.2 1.0 2.9 3 0 0 3 3 3 2 Abl-interactor HHR Aldo_ket_red PF00248.16 EMD67304.1 - 1.6e-53 181.3 0.0 1.8e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LCCL PF03815.14 EMD67305.1 - 3.9e-20 71.6 0.0 7.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 EMD67306.1 - 7.4e-07 28.4 0.0 8.5e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1115 PF06544.7 EMD67307.1 - 7.5e-15 54.7 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3237 PF11578.3 EMD67308.1 - 9.4e-29 99.6 0.0 2.1e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Pkinase PF00069.20 EMD67309.1 - 4.9e-15 55.3 0.0 4.2e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67309.1 - 1.2e-07 31.0 0.0 0.018 14.1 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMD67309.1 - 0.18 11.5 1.1 0.37 10.4 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family FAT PF02259.18 EMD67310.1 - 9.8e-75 251.7 6.5 9.8e-75 251.7 4.5 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EMD67310.1 - 2.9e-28 98.9 0.1 1.2e-27 96.9 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMD67310.1 - 2.4e-05 23.6 0.2 0.0001 21.6 0.1 2.2 1 0 0 1 1 1 1 FATC domain DUF2874 PF11396.3 EMD67310.1 - 1.1 9.2 3.4 37 4.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) COX5A PF02284.11 EMD67311.1 - 2.1e-43 146.6 0.4 3.1e-43 146.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Tau95 PF09734.4 EMD67312.1 - 4.1e-57 193.8 0.0 7.6e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EMD67313.1 - 1.7e-173 576.9 6.6 2.1e-173 576.6 4.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ELO PF01151.13 EMD67314.1 - 1.6e-61 207.7 18.5 1.9e-61 207.5 12.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Opi1 PF08618.5 EMD67315.1 - 9e-61 206.0 10.7 6.8e-36 124.1 7.6 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 HTH_29 PF13551.1 EMD67315.1 - 0.00056 20.0 0.3 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 Winged helix-turn helix TPR_12 PF13424.1 EMD67316.1 - 5.5e-20 71.0 0.0 4.8e-11 42.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD67316.1 - 9e-15 54.0 0.0 5.1e-07 29.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD67316.1 - 1.7e-07 30.7 0.0 6.8e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 EMD67316.1 - 2.6e-06 26.7 0.1 0.0058 16.3 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD67316.1 - 3.8e-05 23.0 0.0 0.0093 15.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EMD67316.1 - 9.1e-05 22.6 0.0 0.00041 20.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMD67316.1 - 9.2e-05 21.4 0.0 0.00056 18.8 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EMD67316.1 - 0.00035 20.2 0.0 0.19 11.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PGAP1 PF07819.8 EMD67316.1 - 0.015 14.9 0.0 0.095 12.2 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein TPR_19 PF14559.1 EMD67316.1 - 0.022 15.1 0.0 0.068 13.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMD67316.1 - 0.051 13.7 0.0 3.1 8.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3226 PF11536.3 EMD67316.1 - 0.076 12.4 0.1 2.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3226) TPR_16 PF13432.1 EMD67316.1 - 0.095 13.4 0.0 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_viral_N PF00242.12 EMD67317.1 - 2.6 6.9 7.5 2.8 6.8 5.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MGC-24 PF05283.6 EMD67317.1 - 7.3 6.3 13.2 8.6 6.1 9.2 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Apc15p PF05841.6 EMD67317.1 - 8.1 7.2 9.3 9.6 6.9 6.4 1.1 1 0 0 1 1 1 0 Apc15p protein ABC2_membrane PF01061.19 EMD67319.1 - 3.4e-85 284.4 55.6 1.4e-44 151.7 11.8 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMD67319.1 - 5.3e-37 127.1 0.0 3.2e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD67319.1 - 7.6e-29 99.4 5.5 4.9e-24 83.9 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMD67319.1 - 2.9e-11 43.2 0.2 9.7e-11 41.6 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EMD67319.1 - 1.3e-08 34.2 41.0 3.4e-06 26.3 13.2 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EMD67319.1 - 1.7e-05 24.3 1.9 0.0034 16.8 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EMD67319.1 - 2.9e-05 24.8 0.0 0.037 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EMD67319.1 - 2.9e-05 24.1 0.0 0.058 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD67319.1 - 4.5e-05 23.6 0.1 0.051 13.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EMD67319.1 - 6.7e-05 22.4 0.2 0.0071 15.7 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD67319.1 - 7.3e-05 22.2 0.4 0.0059 16.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EMD67319.1 - 9.3e-05 22.3 0.0 0.058 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD67319.1 - 0.00021 20.5 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD67319.1 - 0.00023 21.1 0.2 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 EMD67319.1 - 0.0013 18.3 0.8 0.8 9.3 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMD67319.1 - 0.0022 18.3 0.0 0.6 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMD67319.1 - 0.0031 16.7 0.0 1.1 8.4 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EMD67319.1 - 0.005 16.3 0.4 1.1 8.7 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EMD67319.1 - 0.0063 16.2 0.5 4.3 7.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EMD67319.1 - 0.013 15.1 0.8 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EMD67319.1 - 0.028 14.4 1.2 0.062 13.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMD67319.1 - 0.051 13.2 0.0 7.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EMD67319.1 - 0.059 12.8 0.2 3.7 6.9 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EMD67319.1 - 0.11 12.7 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMD67319.1 - 0.12 12.8 0.1 5.7 7.4 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_15 PF13175.1 EMD67319.1 - 0.17 10.9 0.0 0.41 9.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EMD67319.1 - 0.2 11.8 0.4 57 3.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.1 EMD67319.1 - 0.29 11.4 3.6 0.5 10.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain TFIID-31kDa PF02291.10 EMD67320.1 - 0.16 11.7 0.1 17 5.2 0.0 2.9 2 1 1 3 3 3 0 Transcription initiation factor IID, 31kD subunit DUF1546 PF07571.8 EMD67321.1 - 4.1e-25 87.7 0.0 1.3e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EMD67321.1 - 1.6e-23 82.3 0.2 1.3e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EMD67321.1 - 0.00052 20.0 0.1 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1778 PF08681.6 EMD67321.1 - 0.061 13.1 0.3 6.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Bromo_TP PF07524.8 EMD67321.1 - 0.071 12.8 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EMD67321.1 - 0.11 12.6 0.1 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Gemini_mov PF01708.11 EMD67322.1 - 0.061 12.8 0.3 0.076 12.5 0.2 1.1 1 0 0 1 1 1 0 Geminivirus putative movement protein Mito_fiss_reg PF05308.6 EMD67322.1 - 0.21 10.9 4.4 0.21 10.9 3.0 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EMD67322.1 - 1.4 8.1 3.7 1.3 8.2 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.24 EMD67323.1 - 1.1e-19 70.5 0.0 2.2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMD67323.1 - 7.5e-09 35.6 0.0 5.3e-08 32.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMD67323.1 - 1.2e-06 28.2 0.1 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_trans_4_2 PF13477.1 EMD67323.1 - 0.028 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like PhoH PF02562.11 EMD67323.1 - 0.048 12.8 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mito_carr PF00153.22 EMD67324.1 - 3.4e-14 52.3 0.8 0.0004 20.0 0.0 5.5 4 1 0 4 4 4 4 Mitochondrial carrier protein S_tail_recep_bd PF14928.1 EMD67324.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Fer2 PF00111.22 EMD67325.1 - 4.6e-15 55.1 0.8 6.2e-15 54.7 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 EMD67326.1 - 1.3e-34 119.0 8.0 1.3e-34 119.0 5.5 3.3 3 1 0 3 3 3 1 Rrp15p Ribosomal_S20p PF01649.13 EMD67326.1 - 2.6 8.4 14.2 1 9.7 0.7 3.6 2 1 2 4 4 4 0 Ribosomal protein S20 SRP54 PF00448.17 EMD67327.1 - 5.3e-76 254.4 1.3 1.4e-75 253.1 0.9 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EMD67327.1 - 3.7e-26 91.3 5.0 3.7e-26 91.3 3.5 4.0 5 0 0 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EMD67327.1 - 3.1e-15 56.0 0.5 7.9e-15 54.7 0.4 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EMD67327.1 - 6.4e-09 35.5 0.1 1.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMD67327.1 - 2.5e-07 30.6 0.0 9.8e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMD67327.1 - 7.9e-06 25.6 0.1 2.6e-05 23.9 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EMD67327.1 - 5.8e-05 22.5 0.1 0.0002 20.8 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EMD67327.1 - 0.00062 19.9 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EMD67327.1 - 0.00078 19.4 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD67327.1 - 0.0013 19.5 0.0 0.0033 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMD67327.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Thymidylate_kin PF02223.12 EMD67327.1 - 0.0021 17.4 0.3 0.0079 15.5 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase APS_kinase PF01583.15 EMD67327.1 - 0.0029 17.2 0.0 0.0064 16.1 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EMD67327.1 - 0.0064 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin TrwB_AAD_bind PF10412.4 EMD67327.1 - 0.013 14.1 0.0 0.025 13.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EMD67327.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD67327.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 EMD67327.1 - 0.039 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 EMD67327.1 - 0.044 13.3 2.4 0.1 12.1 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF3052 PF11253.3 EMD67327.1 - 0.056 13.0 1.4 0.085 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) AAA_19 PF13245.1 EMD67327.1 - 0.068 12.9 0.2 0.3 10.8 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_28 PF13521.1 EMD67327.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMD67327.1 - 0.14 11.3 1.9 5 6.3 0.6 3.2 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit FMO-like PF00743.14 EMD67328.1 - 4.6e-36 124.1 0.0 2.5e-21 75.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMD67328.1 - 1.2e-17 64.6 0.0 1.6e-16 60.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD67328.1 - 2.7e-10 39.7 0.4 9.9e-08 31.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD67328.1 - 2.5e-08 33.7 0.0 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD67328.1 - 3.5e-08 33.3 0.1 1.5e-06 28.0 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD67328.1 - 2.9e-07 30.5 0.0 8.9e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD67328.1 - 3.1e-06 26.4 0.1 7.5e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EMD67328.1 - 0.0044 15.5 0.0 0.054 11.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EMD67328.1 - 0.016 14.1 0.3 0.16 10.8 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMD67328.1 - 0.047 12.7 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ins_allergen_rp PF06757.8 EMD67328.1 - 0.12 11.8 0.1 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification NMT1 PF09084.6 EMD67329.1 - 2.1e-07 30.7 0.0 4.6e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EMD67329.1 - 1.3e-05 24.6 0.0 2.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EMD67329.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_1 PF01547.20 EMD67329.1 - 0.012 15.4 0.0 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Transferase PF02458.10 EMD67330.1 - 1.7e-16 59.7 0.0 3.6e-11 42.1 0.0 3.4 3 1 0 3 3 3 3 Transferase family zf-C2H2 PF00096.21 EMD67331.1 - 5.6e-05 23.2 26.6 0.0063 16.7 1.1 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMD67331.1 - 7e-05 22.8 12.3 0.3 11.2 2.3 3.8 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EMD67331.1 - 0.00015 21.8 27.0 0.00029 20.9 0.4 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD67331.1 - 0.00074 19.6 33.6 0.013 15.8 0.5 6.5 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD67331.1 - 0.01 15.9 17.8 0.052 13.7 0.6 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 EMD67331.1 - 0.44 10.6 11.0 0.026 14.5 2.9 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L19 PF01245.15 EMD67333.1 - 2.9e-18 65.6 0.1 5.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Integrase_Zn PF02022.14 EMD67333.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain NmrA PF05368.8 EMD67334.1 - 2e-62 210.4 0.0 2.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD67334.1 - 2.9e-06 27.3 0.0 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Asparaginase PF00710.15 EMD67335.1 - 9.4e-99 330.2 0.0 1.3e-98 329.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 EMD67335.1 - 8.6e-13 47.4 1.0 0.00018 21.1 0.4 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EMD67335.1 - 1.3e-12 47.8 0.0 2.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD67335.1 - 1.2e-09 38.3 0.1 5.8e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD67335.1 - 2.7e-08 33.7 0.6 1.1e-05 25.5 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67335.1 - 4.4e-05 23.3 0.2 0.039 14.1 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat NAP PF00956.13 EMD67337.1 - 1.2e-42 145.7 5.1 1.2e-42 145.7 3.5 2.0 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EMD67337.1 - 0.0042 17.1 15.3 0.12 12.5 6.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) BUD22 PF09073.5 EMD67337.1 - 2.6 6.9 16.6 4.8 6.1 11.5 1.4 1 1 0 1 1 1 0 BUD22 Glyco_hydro_1 PF00232.13 EMD67338.1 - 6.5e-102 341.0 0.1 9.5e-102 340.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 WD40 PF00400.27 EMD67338.1 - 6.5e-26 89.2 9.5 2e-07 30.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD67338.1 - 8.4e-05 22.3 0.0 0.76 9.4 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 EMD67338.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Coatomer_WDAD PF04053.9 EMD67338.1 - 0.27 9.9 0.3 1.8 7.2 0.1 2.1 2 0 0 2 2 2 0 Coatomer WD associated region TP6A_N PF04406.9 EMD67340.1 - 1.2e-20 72.9 0.1 2.8e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase CAF1A PF12253.3 EMD67341.1 - 1.1e-25 89.5 8.7 1.1e-25 89.5 6.1 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EMD67341.1 - 2.1e-05 24.0 49.0 3.2e-05 23.4 29.1 2.6 1 1 1 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EMD67341.1 - 0.0091 13.7 7.1 0.011 13.4 4.9 1.1 1 0 0 1 1 1 1 Ycf1 Raftlin PF15250.1 EMD67341.1 - 0.83 8.1 11.4 1.4 7.3 7.9 1.3 1 0 0 1 1 1 0 Raftlin RNase_H2-Ydr279 PF09468.5 EMD67341.1 - 1.9 7.6 18.1 2.9 7.0 12.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pox_Ag35 PF03286.9 EMD67341.1 - 4.2 6.8 23.0 5.2 6.5 12.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Tho2 PF11262.3 EMD67341.1 - 4.2 6.3 9.4 7.6 5.4 6.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GAGA_bind PF06217.7 EMD67341.1 - 6.1 6.7 15.2 13 5.6 10.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Asp PF00026.18 EMD67342.1 - 6.4e-10 38.7 2.3 2.4e-09 36.8 1.6 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EMD67342.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EMD67342.1 - 0.14 10.8 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Ribonucleas_3_3 PF14622.1 EMD67343.1 - 1.6e-27 95.9 0.0 5.5e-27 94.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD67343.1 - 2.1e-05 24.9 0.0 5e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 EMD67344.1 - 9.4e-101 337.3 0.0 1.2e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_tranf_2_3 PF13641.1 EMD67345.1 - 6.4e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMD67345.1 - 1.3e-12 47.3 0.2 3.4e-05 23.2 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMD67345.1 - 0.0029 17.2 0.0 0.073 12.7 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 TrkH PF02386.11 EMD67346.1 - 3.1e-117 391.1 12.4 1.6e-115 385.5 5.9 2.1 2 0 0 2 2 2 2 Cation transport protein Glycogen_syn PF05693.8 EMD67347.1 - 0 1098.6 0.0 0 1098.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EMD67347.1 - 2.8e-07 30.1 0.0 0.0042 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMD67347.1 - 1.1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EMD67347.1 - 0.00035 20.1 0.0 0.00084 18.9 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain PH PF00169.24 EMD67348.1 - 0.00063 19.9 0.4 0.0016 18.6 0.3 1.6 1 0 0 1 1 1 1 PH domain CAF-1_p150 PF11600.3 EMD67348.1 - 0.0047 16.3 34.2 0.018 14.4 23.7 2.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAML PF14963.1 EMD67348.1 - 9.4 5.5 11.6 20 4.4 8.0 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand F-box-like PF12937.2 EMD67349.1 - 6.4e-06 25.7 0.0 2.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EMD67349.1 - 0.005 16.4 0.0 4 7.1 0.0 4.0 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) zf-RanBP PF00641.13 EMD67350.1 - 1.2e-20 72.3 11.1 1.2e-10 40.2 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EMD67350.1 - 3.3e-08 33.0 0.0 1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD67350.1 - 8.9e-07 28.8 0.0 7.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMD67350.1 - 1.1e-06 29.0 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EMD67350.1 - 1.9 8.3 10.8 1.4 8.8 1.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Mannosyl_trans3 PF11051.3 EMD67351.1 - 1.6e-72 244.1 0.0 7.7e-72 241.8 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Cnd3 PF12719.2 EMD67352.1 - 5.8e-87 291.4 0.1 1.7e-86 289.8 0.1 1.8 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EMD67352.1 - 4.6e-10 38.7 0.4 0.026 14.5 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EMD67352.1 - 5.8e-07 29.6 5.2 0.00022 21.4 0.2 4.8 3 1 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EMD67352.1 - 0.0022 18.4 4.9 0.022 15.2 0.1 4.8 6 1 0 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EMD67352.1 - 0.0043 16.9 1.5 0.55 10.2 0.1 3.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EMD67352.1 - 0.044 13.6 0.1 22 4.8 0.0 4.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMD67352.1 - 0.044 14.1 0.0 0.47 10.8 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region PALP PF00291.20 EMD67353.1 - 1.1e-60 205.4 0.1 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUDIX-like PF09296.6 EMD67354.1 - 1.8e-17 63.4 0.0 1.1e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EMD67354.1 - 3.2e-17 62.4 0.1 5.5e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EMD67354.1 - 8.1e-05 22.0 0.7 0.00019 20.8 0.5 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain SBDS_C PF09377.5 EMD67354.1 - 0.078 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 SBDS protein C-terminal domain COG2 PF06148.6 EMD67355.1 - 3.4e-34 117.5 0.8 3.4e-34 117.5 0.5 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EMD67355.1 - 3.9e-05 23.3 1.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 EMD67355.1 - 0.00092 19.1 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Ribosomal_L1 PF00687.16 EMD67356.1 - 7.1e-29 100.7 0.0 1e-28 100.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Meiotic_rec114 PF03525.9 EMD67356.1 - 0.043 12.3 0.0 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Acetyltransf_3 PF13302.1 EMD67357.1 - 1e-18 67.8 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD67357.1 - 0.0046 16.9 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Lipase_GDSL PF00657.17 EMD67358.1 - 4.8e-05 23.3 4.1 0.00011 22.0 2.9 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMD67358.1 - 0.00019 21.6 0.1 0.00034 20.7 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Scramblase PF03803.10 EMD67360.1 - 1e-52 178.4 0.0 3.1e-29 101.6 0.0 2.9 1 1 1 2 2 2 2 Scramblase tRNA_int_endo PF01974.12 EMD67361.1 - 2.9e-19 68.6 0.0 7.4e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EMD67361.1 - 0.00027 20.4 0.0 0.0059 16.1 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Asn_synthase PF00733.16 EMD67362.1 - 1.4e-57 195.1 0.0 1.9e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMD67362.1 - 2.6e-35 120.8 0.0 8.5e-35 119.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMD67362.1 - 6.4e-32 110.3 0.0 1.5e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMD67362.1 - 0.00093 17.9 0.0 0.077 11.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EMD67362.1 - 0.0075 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 EMD67362.1 - 0.19 10.2 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase WD40 PF00400.27 EMD67363.1 - 2.1e-32 109.8 1.0 1.5e-10 40.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMD67363.1 - 1.7e-28 98.3 0.3 4.8e-28 96.8 0.2 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_hydro_2 PF00703.16 EMD67364.1 - 7.9e-10 39.1 0.0 1.8e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EMD67364.1 - 2.5e-08 33.6 0.0 6.2e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMD67364.1 - 0.0029 16.5 0.0 0.0053 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_72 PF03198.9 EMD67364.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase CoaE PF01121.15 EMD67365.1 - 8e-44 149.1 0.0 1.3e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EMD67365.1 - 0.00026 20.8 0.0 0.0037 17.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD67365.1 - 0.00072 20.3 1.4 0.0051 17.6 1.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD67365.1 - 0.12 12.6 0.8 0.41 10.9 0.4 2.2 1 1 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.19 EMD67369.1 - 2.3e-29 102.4 0.8 3.5e-29 101.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD67369.1 - 1.6e-19 69.1 1.5 4e-19 67.8 0.8 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD67369.1 - 5.4e-19 68.8 0.1 1.3e-18 67.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD67369.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 EMD67370.1 - 1.9e-28 99.4 0.2 2.5e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67370.1 - 1.4e-25 90.4 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67370.1 - 3.6e-15 56.0 0.1 4.9e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF4164 PF13747.1 EMD67372.1 - 0.25 11.4 7.0 0.067 13.3 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DIOX_N PF14226.1 EMD67373.1 - 3.7e-24 85.4 0.0 5.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD67373.1 - 2.5e-21 75.8 0.0 4.4e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_3 PF07969.6 EMD67374.1 - 3.4e-57 194.4 0.7 3.9e-57 194.2 0.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD67374.1 - 2.8e-09 36.6 0.1 1.1e-08 34.7 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD67374.1 - 3.6e-09 36.7 0.8 7.5e-08 32.3 0.6 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMD67374.1 - 0.00013 22.0 3.8 0.37 10.7 1.3 3.1 2 1 0 2 2 2 2 Amidohydrolase YbjQ_1 PF01906.12 EMD67375.1 - 5.9e-21 74.8 0.4 7.3e-21 74.5 0.3 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Alpha-L-AF_C PF06964.7 EMD67376.1 - 1.6e-21 76.8 0.0 2.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus cobW PF02492.14 EMD67377.1 - 1.2e-49 168.1 3.5 1.2e-47 161.6 2.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMD67377.1 - 5.9e-19 67.5 0.0 1.7e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Gp_dh_N PF00044.19 EMD67377.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Arch_ATPase PF01637.13 EMD67377.1 - 0.0098 15.6 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EMD67377.1 - 0.014 15.2 0.0 0.085 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EMD67377.1 - 0.015 14.1 0.6 2.1 7.0 0.1 2.7 2 1 0 2 2 2 0 ArgK protein Viral_helicase1 PF01443.13 EMD67377.1 - 0.016 14.7 0.1 0.044 13.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EMD67377.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMD67377.1 - 0.036 14.3 1.8 0.09 13.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EMD67377.1 - 0.036 13.7 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMD67377.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMD67377.1 - 0.085 12.8 0.4 0.37 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EMD67377.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Herpes_LMP2 PF07415.6 EMD67377.1 - 6.8 5.1 4.6 10 4.5 3.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Melibiase PF02065.13 EMD67378.1 - 1.7e-17 63.1 3.7 4.1e-14 52.1 0.1 3.3 3 1 0 3 3 3 3 Melibiase Glyco_hyd_65N_2 PF14498.1 EMD67379.1 - 2.7e-61 207.2 0.5 3.8e-61 206.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain MCM PF00493.18 EMD67380.1 - 1.4e-141 471.0 0.1 1.9e-141 470.6 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMD67380.1 - 5.3e-19 68.8 2.2 5.8e-19 68.7 0.2 2.1 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMD67380.1 - 3.7e-06 26.2 0.0 0.00075 18.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMD67380.1 - 2.3e-05 24.1 0.0 6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMD67380.1 - 0.00047 19.7 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMD67380.1 - 0.03 13.7 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EMD67380.1 - 0.043 14.2 3.1 0.24 11.8 0.2 3.0 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Hap4_Hap_bind PF10297.4 EMD67382.1 - 2.3e-06 27.2 6.4 2.3e-06 27.2 4.4 1.9 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EMD67382.1 - 1e-05 25.3 15.2 0.0043 16.9 6.0 2.5 1 1 1 2 2 2 2 bZIP transcription factor HALZ PF02183.13 EMD67382.1 - 0.0048 16.5 0.8 0.014 15.1 0.6 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DegS PF05384.6 EMD67382.1 - 0.02 14.0 0.7 0.036 13.2 0.4 1.5 1 1 0 1 1 1 0 Sensor protein DegS DUF4618 PF15397.1 EMD67382.1 - 0.11 11.8 6.8 0.16 11.2 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_2 PF07716.10 EMD67382.1 - 0.12 12.1 11.6 0.076 12.8 3.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF2205 PF10224.4 EMD67382.1 - 0.44 10.1 6.0 4.4 6.9 0.1 2.3 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EMD67382.1 - 6.5 6.3 8.9 11 5.5 6.2 1.2 1 0 0 1 1 1 0 IncA protein PE PF00934.15 EMD67383.1 - 0.061 13.4 1.8 0.078 13.0 1.3 1.2 1 0 0 1 1 1 0 PE family DUF3317 PF11779.3 EMD67385.1 - 0.61 9.5 3.1 0.82 9.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) NiFeSe_Hases PF00374.14 EMD67388.1 - 0.065 11.9 0.0 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Glyco_hydro_61 PF03443.9 EMD67389.1 - 1.2e-41 142.9 0.2 1.4e-41 142.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transglut_core PF01841.14 EMD67390.1 - 1.3e-12 47.9 0.0 3.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EMD67390.1 - 9.8e-09 34.5 0.1 2.1e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMD67390.1 - 7.2e-08 31.7 0.1 1.6e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD67390.1 - 6.6e-06 25.6 0.1 1.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain CCDC32 PF14989.1 EMD67390.1 - 0.044 13.6 1.0 0.078 12.8 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 LIM_bind PF01803.11 EMD67390.1 - 0.085 11.9 0.2 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 LIM-domain binding protein DUF1900 PF08954.6 EMD67390.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) tRNA-synt_1c PF00749.16 EMD67391.1 - 7.7e-101 336.8 0.0 1e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMD67391.1 - 2.7e-34 118.3 0.1 5.6e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EMD67391.1 - 0.00029 21.2 0.1 0.001 19.5 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GFA PF04828.9 EMD67392.1 - 3e-10 39.8 2.7 3e-10 39.8 1.9 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.7 EMD67392.1 - 0.063 12.8 5.8 0.87 9.2 0.3 2.5 2 0 0 2 2 2 0 LSD1 zinc finger Exo_endo_phos PF03372.18 EMD67393.1 - 4.2e-24 85.8 0.0 7.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pectate_lyase22 PF14583.1 EMD67393.1 - 0.037 12.4 0.1 0.06 11.8 0.1 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase zf-CHY PF05495.7 EMD67394.1 - 1.6e-15 57.0 17.0 2.1e-15 56.6 11.8 1.1 1 0 0 1 1 1 1 CHY zinc finger HypA PF01155.14 EMD67394.1 - 0.011 15.3 1.2 0.011 15.3 0.8 2.4 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 EMD67394.1 - 0.012 15.6 2.9 0.012 15.6 2.0 2.4 1 1 2 3 3 3 0 zinc-finger zinc_ribbon_2 PF13240.1 EMD67394.1 - 0.5 9.9 7.4 1 8.9 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DRP PF06044.7 EMD67394.1 - 0.59 9.0 4.1 0.2 10.6 0.7 1.7 1 1 1 2 2 2 0 Dam-replacing family DUF3797 PF12677.2 EMD67394.1 - 0.8 9.3 0.0 0.8 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.8 EMD67394.1 - 0.98 9.3 9.9 24 4.8 6.8 2.5 1 1 0 1 1 1 0 Erv1 / Alr family C1_4 PF07975.7 EMD67394.1 - 2.4 8.2 13.9 0.46 10.5 2.8 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain DZR PF12773.2 EMD67394.1 - 3.6 7.4 12.6 34 4.3 8.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EMD67394.1 - 4.3 7.0 11.6 7.2 6.3 8.0 1.5 1 1 0 1 1 1 0 Cytochrome c7 zf-C2H2 PF00096.21 EMD67394.1 - 9.3 6.8 11.1 3 8.3 0.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Proteasome PF00227.21 EMD67395.1 - 1.7e-55 187.2 0.1 2.3e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMD67395.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 EMD67396.1 - 2.2e-58 197.5 0.0 2.9e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMD67396.1 - 7.6e-37 125.8 0.1 1.3e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amidohydro_2 PF04909.9 EMD67397.1 - 1e-29 103.9 0.0 1.5e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase MTHFR PF02219.12 EMD67398.1 - 1.3e-100 336.2 0.0 2.5e-100 335.3 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF3449 PF11931.3 EMD67399.1 - 5.1e-74 248.0 1.0 1.9e-73 246.2 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EMD67399.1 - 5.9e-10 38.9 1.8 5.9e-08 32.6 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD67399.1 - 1.8e-07 31.0 0.6 1.8e-07 31.0 0.5 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 EMD67399.1 - 0.00054 19.4 0.4 0.0014 18.0 0.1 1.9 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.2 EMD67399.1 - 0.0019 18.2 0.9 0.015 15.3 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EMD67399.1 - 0.084 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DEAD PF00270.24 EMD67400.1 - 1.5e-39 135.1 0.3 3.3e-39 134.0 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD67400.1 - 5e-28 96.7 0.2 1e-27 95.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMD67400.1 - 0.00078 19.1 0.2 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 EMD67400.1 - 0.0089 15.7 0.3 0.032 13.9 0.1 2.2 1 1 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.1 EMD67400.1 - 0.0094 15.5 0.4 0.022 14.3 0.3 1.5 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.9 EMD67400.1 - 0.011 15.0 0.3 0.022 14.0 0.1 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.10 EMD67400.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EMD67400.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 EMD67400.1 - 0.066 12.3 0.1 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EMD67400.1 - 0.13 11.7 0.3 0.17 11.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 EMD67403.1 - 1.3e-26 92.7 0.0 1.4e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2293 PF10056.4 EMD67407.1 - 3.2e-29 100.7 2.6 4.4e-29 100.2 0.1 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) Anoctamin PF04547.7 EMD67408.1 - 7.7e-106 354.4 0.2 9.6e-106 354.1 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Glyco_hydro_10 PF00331.15 EMD67409.1 - 2.5e-101 338.8 3.3 2.9e-101 338.6 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 NAD_binding_10 PF13460.1 EMD67410.1 - 6.2e-12 45.9 0.4 1e-11 45.1 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD67410.1 - 2.9e-10 39.7 0.0 4.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMD67410.1 - 4.2e-05 23.8 0.1 7.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMD67410.1 - 0.0003 20.7 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EMD67410.1 - 0.0019 18.7 0.2 0.0032 17.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 EMD67410.1 - 0.018 14.5 0.1 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EMD67410.1 - 0.033 14.0 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2325 PF10087.4 EMD67410.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) DXP_reductoisom PF02670.11 EMD67410.1 - 0.11 13.0 0.4 0.94 10.0 0.1 2.1 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ADH_N PF08240.7 EMD67411.1 - 4e-33 113.4 1.4 5.6e-33 112.9 0.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD67411.1 - 8e-15 54.5 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2338 PF10100.4 EMD67411.1 - 0.035 12.4 0.0 0.047 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) DUF572 PF04502.8 EMD67414.1 - 1.3e-72 244.7 18.1 6.9e-72 242.3 12.3 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EMD67414.1 - 0.023 14.1 0.5 0.041 13.3 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EMD67414.1 - 0.12 12.2 0.9 0.27 11.1 0.6 1.5 1 1 0 1 1 1 0 Benyvirus 14KDa protein SprT-like PF10263.4 EMD67414.1 - 0.15 11.7 0.5 0.24 11.0 0.4 1.5 1 0 0 1 1 1 0 SprT-like family zf-FCS PF06467.9 EMD67414.1 - 0.53 9.9 4.6 0.47 10.1 0.4 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Apc3 PF12895.2 EMD67415.1 - 8.1e-29 99.6 6.7 6e-21 74.3 0.2 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMD67415.1 - 2.1e-28 97.7 8.7 4.2e-06 26.3 0.0 7.0 5 2 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 EMD67415.1 - 2.1e-27 93.5 0.6 3.2e-06 26.4 0.2 9.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMD67415.1 - 5.8e-25 85.1 9.4 6.9e-05 22.4 0.1 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67415.1 - 7.1e-21 74.3 1.4 0.011 16.0 0.1 7.5 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67415.1 - 3.5e-19 68.5 11.2 2e-07 30.8 0.0 7.5 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67415.1 - 3e-16 59.6 6.1 0.0027 18.3 0.0 7.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67415.1 - 1.1e-15 56.1 0.0 0.0001 21.8 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67415.1 - 2.1e-12 46.5 10.3 0.39 11.4 0.0 9.0 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD67415.1 - 4e-08 32.8 0.1 0.75 10.1 0.0 7.6 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD67415.1 - 2.3e-07 30.0 6.5 1.1 9.2 0.0 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMD67415.1 - 6.8e-06 25.3 0.5 1.2 8.1 0.0 4.7 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMD67415.1 - 1e-05 25.6 4.8 1.1 9.8 0.1 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD67415.1 - 8.4e-05 22.3 1.6 7.6 6.6 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMD67415.1 - 0.00032 20.4 9.8 0.47 10.3 0.2 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.2 EMD67415.1 - 0.018 15.0 0.1 0.16 12.0 0.0 2.7 4 0 0 4 4 3 0 Tetratrico peptide repeat ATP11 PF06644.6 EMD67415.1 - 0.034 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP11 protein Fis1_TPR_C PF14853.1 EMD67415.1 - 0.35 10.7 7.6 1.1 9.1 0.1 4.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat bZIP_1 PF00170.16 EMD67415.1 - 5.4 7.0 7.6 7.9 6.5 4.1 2.1 1 1 1 2 2 2 0 bZIP transcription factor TMV_coat PF00721.16 EMD67416.1 - 0.0075 16.1 2.0 0.022 14.7 1.4 1.8 1 0 0 1 1 1 1 Virus coat protein (TMV like) EMP24_GP25L PF01105.19 EMD67417.1 - 1.9e-45 154.8 2.4 2.2e-45 154.6 1.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD rve PF00665.21 EMD67417.1 - 0.089 12.8 0.3 0.27 11.3 0.2 1.8 2 0 0 2 2 2 0 Integrase core domain USP7_ICP0_bdg PF12436.3 EMD67418.1 - 2.8e-83 278.9 0.5 1.7e-81 273.1 0.0 2.9 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EMD67418.1 - 7.6e-66 221.5 0.6 4e-65 219.2 0.2 2.4 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EMD67418.1 - 1e-52 178.9 1.7 2.6e-52 177.6 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD67418.1 - 1e-29 103.9 0.0 2.1e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EMD67418.1 - 6.2e-10 39.3 0.2 4e-09 36.7 0.0 2.6 2 1 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EMD67418.1 - 0.012 15.2 0.6 4 7.2 0.0 3.3 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like HTH_Tnp_1 PF01527.15 EMD67418.1 - 0.017 15.0 0.3 0.096 12.6 0.0 2.4 2 1 1 3 3 3 0 Transposase CRS1_YhbY PF01985.16 EMD67418.1 - 0.15 12.0 0.0 14 5.7 0.0 2.8 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain BCDHK_Adom3 PF10436.4 EMD67419.1 - 1.4e-33 115.7 0.1 2.2e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMD67419.1 - 3.5e-10 39.5 0.0 6e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMD67419.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Oxidored_molyb PF00174.14 EMD67422.1 - 4.2e-54 182.4 0.0 6.2e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMD67422.1 - 1.1e-28 99.4 1.0 2.2e-28 98.5 0.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain UPF0270 PF06794.7 EMD67422.1 - 0.014 15.1 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) UQ_con PF00179.21 EMD67423.1 - 4.2e-53 178.5 0.0 4.7e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD67423.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B FAD_binding_8 PF08022.7 EMD67424.1 - 1.4e-21 76.2 0.0 2.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD67424.1 - 6.7e-18 65.0 0.0 1.7e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMD67424.1 - 2.1e-09 37.5 6.6 2.1e-09 37.5 4.6 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMD67424.1 - 0.00052 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain EF-hand_7 PF13499.1 EMD67424.1 - 0.0013 18.8 0.6 0.0029 17.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMD67424.1 - 0.14 11.5 0.9 0.32 10.4 0.3 1.9 2 0 0 2 2 2 0 EF hand Abhydrolase_3 PF07859.8 EMD67425.1 - 2.8e-28 98.9 0.0 3.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Oxidored_q6 PF01058.17 EMD67426.1 - 9.5e-23 80.2 0.1 1.3e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Response_reg PF00072.19 EMD67427.1 - 1e-12 48.0 0.1 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Glyco_transf_25 PF01755.12 EMD67428.1 - 2.7e-11 43.5 0.0 1.6e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_34 PF05637.7 EMD67429.1 - 1.2e-09 37.9 0.1 8.8e-06 25.3 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF3184 PF11380.3 EMD67430.1 - 0.017 13.0 0.0 0.026 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) EF-hand_8 PF13833.1 EMD67430.1 - 0.26 10.9 2.4 0.3 10.7 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair Head_binding PF09008.5 EMD67431.1 - 0.31 11.1 3.8 0.12 12.3 0.6 1.9 2 0 0 2 2 2 0 Head binding Acyl_transf_3 PF01757.17 EMD67432.1 - 9.2e-25 87.1 27.7 1.6e-24 86.4 19.2 1.4 1 0 0 1 1 1 1 Acyltransferase family FAD_binding_3 PF01494.14 EMD67433.1 - 2.7e-17 62.8 0.2 4e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD67433.1 - 1.3e-09 37.4 4.5 0.00027 19.9 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMD67433.1 - 8.1e-07 28.0 4.0 0.00092 17.9 0.2 2.5 2 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EMD67433.1 - 5.5e-05 22.2 2.7 0.00078 18.4 1.7 2.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMD67433.1 - 0.00043 20.2 2.5 0.00061 19.7 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD67433.1 - 0.0021 17.9 0.1 0.19 11.5 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD67433.1 - 0.0045 16.7 1.1 0.068 12.9 0.6 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF3297 PF11730.3 EMD67433.1 - 0.024 14.2 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Pyr_redox_3 PF13738.1 EMD67433.1 - 0.036 14.1 0.1 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD67433.1 - 0.095 11.5 3.6 0.049 12.4 0.8 1.7 2 0 0 2 2 2 0 FAD binding domain SE PF08491.5 EMD67433.1 - 0.16 10.8 0.0 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Fungal_trans PF04082.13 EMD67436.1 - 2.6e-08 33.0 1.7 7.2e-08 31.6 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_11 PF00457.12 EMD67437.1 - 1.2e-42 145.3 19.0 1.8e-42 144.7 13.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF1446 PF07287.6 EMD67438.1 - 4.7e-22 77.9 0.0 5.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Pyr_redox_3 PF13738.1 EMD67439.1 - 8e-09 35.8 0.0 7.6e-05 22.8 0.0 3.0 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD67439.1 - 5.6e-08 32.6 0.1 1.4e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMD67439.1 - 0.00067 17.9 0.0 0.0017 16.6 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD67439.1 - 0.00094 18.1 0.1 0.9 8.3 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD67439.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cut8_C PF08559.5 EMD67439.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Cut8 six-helix bundle Thi4 PF01946.12 EMD67439.1 - 0.13 11.3 0.0 0.29 10.1 0.0 1.5 1 1 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMD67439.1 - 0.18 10.2 0.0 1.6 7.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_2_N PF02837.13 EMD67440.1 - 4e-06 26.4 0.1 9.1e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain HET PF06985.6 EMD67441.1 - 4.3e-30 104.6 1.9 7.4e-30 103.9 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMD67442.1 - 2.3e-06 27.8 0.0 5.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD67442.1 - 2.3e-06 27.1 0.0 0.0079 15.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMD67442.1 - 1.2e-05 25.4 0.0 0.082 13.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67442.1 - 0.072 13.3 0.0 9 6.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF486 PF04342.7 EMD67443.1 - 0.087 12.8 1.0 0.79 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF486 CVNH PF08881.5 EMD67444.1 - 2.6e-31 107.9 0.2 2.9e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 CVNH domain DUF290 PF01060.18 EMD67444.1 - 0.13 12.2 0.4 2.4 8.2 0.0 2.2 1 1 0 2 2 2 0 Transthyretin-like family RIX1 PF08167.7 EMD67449.1 - 6.3e-50 169.0 1.3 1.3e-49 168.0 0.9 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis IL34 PF15036.1 EMD67449.1 - 0.097 12.2 0.1 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Interleukin 34 TPR_2 PF07719.12 EMD67450.1 - 1e-15 56.2 3.2 0.016 15.0 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67450.1 - 5.4e-14 51.4 8.4 0.13 13.0 0.0 8.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD67450.1 - 7e-12 44.8 5.1 0.008 15.8 0.0 6.3 7 0 0 7 7 7 3 TPR repeat TPR_1 PF00515.23 EMD67450.1 - 5e-10 38.5 3.9 0.028 14.0 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67450.1 - 1.5e-08 35.1 9.1 0.44 11.2 0.2 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67450.1 - 2.7e-07 30.8 4.6 0.066 13.5 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67450.1 - 9.4e-07 28.6 7.4 1.2 9.0 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67450.1 - 9.8e-07 28.1 0.5 0.015 15.0 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD67450.1 - 2.7e-06 27.1 0.1 0.88 9.9 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD67450.1 - 0.0038 16.9 3.9 20 5.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMD67450.1 - 0.052 13.4 1.7 0.47 10.3 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Fe_hyd_SSU PF02256.12 EMD67450.1 - 0.098 12.6 2.2 0.12 12.3 0.4 2.1 2 0 0 2 2 2 0 Iron hydrogenase small subunit TPR_6 PF13174.1 EMD67450.1 - 0.14 12.6 12.0 16 6.1 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat p450 PF00067.17 EMD67451.1 - 2.5e-75 253.7 0.0 3e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EMD67453.1 - 1.6e-09 37.5 0.0 0.00041 19.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMD67453.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMD67453.1 - 0.00018 21.5 0.0 0.00044 20.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD67453.1 - 0.00032 19.6 0.0 0.0018 17.2 0.0 2.1 2 1 1 3 3 3 1 Male sterility protein NmrA PF05368.8 EMD67453.1 - 0.0006 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.11 EMD67453.1 - 0.039 14.4 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sec1 PF00995.18 EMD67454.1 - 1.1e-149 499.6 0.1 1.3e-149 499.4 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Fungal_trans PF04082.13 EMD67455.1 - 3.8e-12 45.6 0.9 6e-12 44.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67455.1 - 4.8e-09 35.9 7.8 8.7e-09 35.1 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR PF03114.13 EMD67457.1 - 1.6e-48 165.2 9.0 2e-48 164.9 6.3 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EMD67457.1 - 3.4e-05 22.9 3.3 4.3e-05 22.5 2.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 EMD67457.1 - 0.21 10.6 6.9 0.35 9.8 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GBP_C PF02841.9 EMD67457.1 - 1 8.4 14.4 0.014 14.6 4.9 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain MscS_TM PF12794.2 EMD67457.1 - 3.9 5.9 3.8 5.5 5.5 2.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 IncA PF04156.9 EMD67457.1 - 4.4 6.8 7.8 7.8 6.0 5.4 1.4 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EMD67457.1 - 7.9 6.2 6.9 18 5.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Nop14 PF04147.7 EMD67459.1 - 0.1 10.5 12.1 0.15 9.9 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMD67459.1 - 8.1 5.6 10.6 15 4.7 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2404 PF10296.4 EMD67460.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) adh_short PF00106.20 EMD67461.1 - 8.8e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67461.1 - 4.3e-09 36.2 0.0 7.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD67461.1 - 7.6e-06 25.5 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMD67461.1 - 0.0019 17.1 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMD67461.1 - 0.0022 17.2 0.1 0.0058 15.9 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EMD67461.1 - 0.003 17.6 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD67461.1 - 0.011 14.3 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD67461.1 - 0.024 13.5 0.0 7.1 5.4 0.0 2.8 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 EMD67461.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Mito_fiss_reg PF05308.6 EMD67462.1 - 0.13 11.5 2.2 0.16 11.2 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator WSC PF01822.14 EMD67463.1 - 3.9e-18 65.1 11.0 3.9e-18 65.1 7.6 4.0 2 1 0 3 3 3 1 WSC domain Ycf1 PF05758.7 EMD67463.1 - 2.1 5.9 9.6 2.6 5.6 6.7 1.0 1 0 0 1 1 1 0 Ycf1 PAP2 PF01569.16 EMD67464.1 - 7.8e-24 83.7 1.3 7.8e-24 83.7 0.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.9 EMD67464.1 - 0.082 12.2 3.7 0.87 8.9 0.1 2.2 2 0 0 2 2 2 0 YhhN-like protein FtsX PF02687.16 EMD67464.1 - 0.44 10.3 7.5 3.9 7.2 0.2 3.1 3 1 0 3 3 3 0 FtsX-like permease family adh_short PF00106.20 EMD67465.1 - 8.8e-19 68.0 0.7 2e-17 63.5 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67465.1 - 1e-11 45.0 0.1 1.1e-10 41.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67465.1 - 1.3e-09 38.0 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMD67465.1 - 0.0094 14.8 0.1 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMD67465.1 - 0.048 13.7 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EMD67465.1 - 0.089 12.2 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EMD67466.1 - 1.6e-14 53.9 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67466.1 - 9.5e-09 35.8 0.0 6.2e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD67466.1 - 6.5e-08 32.2 0.0 2.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD67466.1 - 1.7e-06 28.0 0.0 1.9e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD67466.1 - 4.9e-06 26.9 0.0 0.0013 19.1 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMD67466.1 - 1.3e-05 24.3 0.0 7.6e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EMD67466.1 - 2.5e-05 24.6 0.0 0.0066 16.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD67466.1 - 4.1e-05 23.0 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EMD67466.1 - 0.00049 20.1 0.0 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EMD67466.1 - 0.0037 17.6 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMD67466.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EMD67466.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMD67466.1 - 0.077 12.1 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EMD67466.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 EMD67466.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA-synt_2b PF00587.20 EMD67467.1 - 1.1e-64 217.2 0.1 2e-64 216.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD67467.1 - 1.8e-22 79.0 0.4 1e-21 76.6 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain Brix PF04427.13 EMD67468.1 - 9.6e-39 133.0 0.1 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EMD67468.1 - 0.0088 14.0 25.4 0.012 13.6 17.6 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 EMD67468.1 - 0.1 11.6 25.2 0.13 11.2 17.5 1.2 1 0 0 1 1 1 0 BUD22 FAD_binding_2 PF00890.19 EMD67469.1 - 0.0015 17.4 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain CAF1 PF04857.15 EMD67470.1 - 1.2e-61 208.4 0.2 1.9e-61 207.6 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease DUF3482 PF11981.3 EMD67470.1 - 0.025 13.8 7.1 0.042 13.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) BAF1_ABF1 PF04684.8 EMD67470.1 - 0.065 12.0 5.8 0.11 11.3 4.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NDUF_B12 PF08122.7 EMD67471.1 - 7.5e-14 51.1 0.7 1.1e-13 50.6 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Sulfate_tra_GLY PF13792.1 EMD67473.1 - 0.13 11.9 0.6 0.17 11.5 0.2 1.3 1 1 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif PBD PF00786.23 EMD67475.1 - 0.00074 19.8 0.1 0.004 17.5 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Neur_chan_memb PF02932.11 EMD67476.1 - 0.0003 20.7 0.0 0.00032 20.6 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region tRNA-synt_His PF13393.1 EMD67477.1 - 7.1e-35 120.5 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMD67477.1 - 6.6e-15 55.1 0.1 9.4e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EMD67477.1 - 3.3e-06 26.1 0.0 0.01 14.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EMD67477.1 - 0.0042 16.3 0.0 0.018 14.2 0.0 2.1 1 1 1 2 2 2 1 tRNA synthetases class II core domain (F) HGTP_anticodon PF03129.15 EMD67477.1 - 0.021 14.7 0.1 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 Anticodon binding domain PAF-AH_p_II PF03403.8 EMD67478.1 - 7.8e-35 119.8 0.0 1e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMD67478.1 - 8.7e-09 35.2 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMD67478.1 - 5.7e-08 31.9 0.4 5.5e-07 28.7 0.3 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMD67478.1 - 2.8e-06 26.3 0.0 0.0002 20.2 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.2 EMD67478.1 - 0.00018 21.4 0.0 0.00058 19.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD67478.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Herpes_BLRF2 PF05812.7 EMD67479.1 - 0.18 11.6 1.0 1 9.1 0.1 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EMD67479.1 - 1 9.3 5.8 0.43 10.5 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor Aldedh PF00171.17 EMD67480.1 - 1.9e-146 488.0 0.2 2.1e-146 487.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMD67480.1 - 1e-05 24.9 0.1 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Fungal_trans PF04082.13 EMD67481.1 - 1.9e-13 49.9 0.0 3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD67481.1 - 7.5e-08 32.1 8.2 1.2e-07 31.5 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4091 PF13320.1 EMD67481.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Ank PF00023.25 EMD67482.1 - 7.8e-10 38.0 0.9 0.00016 21.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EMD67482.1 - 4.3e-08 33.3 0.0 5.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD67482.1 - 1.6e-05 24.9 0.4 0.031 14.5 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67482.1 - 7.1e-05 22.6 0.1 0.021 15.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EMD67482.1 - 0.0025 18.2 0.0 0.73 10.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Pho88 PF10032.4 EMD67483.1 - 1.9e-82 275.1 0.0 2.1e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) UCH_1 PF13423.1 EMD67484.1 - 1.1e-67 228.5 0.0 3.7e-67 226.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EMD67484.1 - 4.4e-18 65.3 0.0 1.3e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 EMD67485.1 - 1.4e-23 82.3 0.0 2.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMD67485.1 - 4.8e-06 26.2 0.0 9.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 SIP PF04954.8 EMD67485.1 - 0.14 12.5 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Siderophore-interacting protein CoA_binding PF02629.14 EMD67486.1 - 2.4e-27 95.2 4.8 1.3e-26 92.9 1.1 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EMD67486.1 - 2e-24 85.9 0.3 4.4e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMD67486.1 - 9e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EMD67486.1 - 0.00014 21.9 0.1 0.0005 20.2 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EMD67486.1 - 0.014 15.9 0.1 0.033 14.7 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2431 PF10354.4 EMD67487.1 - 6.9e-50 169.2 0.0 2.3e-49 167.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Ctr PF04145.10 EMD67487.1 - 6.6 6.7 6.0 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family CLTH PF10607.4 EMD67488.1 - 3.8e-27 94.7 0.0 9.3e-27 93.4 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain FUSC PF04632.7 EMD67488.1 - 0.12 10.7 3.7 0.16 10.3 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adaptin_binding PF10199.4 EMD67488.1 - 0.14 12.4 0.2 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ABC_tran PF00005.22 EMD67489.1 - 8.8e-47 158.8 0.1 1.8e-23 83.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EMD67489.1 - 1.2e-20 73.1 3.2 1.2e-20 73.1 2.2 2.4 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EMD67489.1 - 7.7e-19 68.7 1.7 0.00054 20.0 0.0 4.4 2 2 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EMD67489.1 - 1.9e-09 36.9 0.1 0.00036 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMD67489.1 - 3.2e-09 36.3 1.0 0.38 9.9 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMD67489.1 - 2.7e-07 29.9 0.0 9e-05 21.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMD67489.1 - 4.9e-07 30.2 11.4 0.022 15.1 0.2 4.2 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.1 EMD67489.1 - 4.2e-06 27.5 0.2 0.036 14.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EMD67489.1 - 1.1e-05 25.7 2.0 0.058 13.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_15 PF13175.1 EMD67489.1 - 1.2e-05 24.5 0.9 0.016 14.2 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EMD67489.1 - 2.1e-05 24.5 0.0 0.022 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMD67489.1 - 3.6e-05 23.9 0.0 0.4 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EMD67489.1 - 6.5e-05 23.4 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 EMD67489.1 - 9.2e-05 22.2 0.1 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Archaeal ATPase NACHT PF05729.7 EMD67489.1 - 0.00011 21.9 0.3 0.17 11.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EMD67489.1 - 0.00016 21.7 2.2 0.48 10.3 0.0 3.4 4 1 0 4 4 2 2 AAA ATPase domain AAA PF00004.24 EMD67489.1 - 0.0002 21.5 0.0 0.44 10.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EMD67489.1 - 0.00021 21.2 0.0 0.053 13.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EMD67489.1 - 0.00021 21.4 0.7 0.99 9.6 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 EMD67489.1 - 0.0013 18.5 0.0 2 8.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD67489.1 - 0.0015 18.3 0.1 1 9.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 EMD67489.1 - 0.0021 17.5 0.3 0.17 11.3 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EMD67489.1 - 0.0024 16.7 0.1 0.58 8.9 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.9 EMD67489.1 - 0.0037 16.9 0.1 3.5 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD67489.1 - 0.0043 16.4 0.0 0.96 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EMD67489.1 - 0.0068 16.2 0.6 0.63 9.9 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Ras PF00071.17 EMD67489.1 - 0.0077 15.6 0.3 2.8 7.2 0.0 2.8 3 0 0 3 3 3 1 Ras family MobB PF03205.9 EMD67489.1 - 0.016 14.9 0.4 0.67 9.6 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EMD67489.1 - 0.018 14.3 0.1 1.4 8.1 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_10 PF12846.2 EMD67489.1 - 0.021 14.2 0.5 2.1 7.7 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EMD67489.1 - 0.027 14.2 0.5 2.8 7.7 0.0 3.3 3 1 1 4 4 4 0 Dynamin family AAA_24 PF13479.1 EMD67489.1 - 0.027 14.0 0.1 7.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EMD67489.1 - 0.042 13.3 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EMD67489.1 - 0.053 12.4 0.0 0.78 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EMD67489.1 - 0.069 12.8 0.4 8.6 6.0 0.1 2.6 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EMD67489.1 - 0.17 11.2 1.6 13 5.1 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 EMD67489.1 - 1.5 7.2 11.6 4.8 5.5 0.0 4.3 4 1 0 4 4 4 0 AAA domain HPP PF04982.8 EMD67490.1 - 2.6e-34 117.6 4.5 2.6e-34 117.6 3.1 1.6 1 1 0 1 1 1 1 HPP family SNF2_N PF00176.18 EMD67491.1 - 1.5e-61 207.8 0.1 2.7e-61 206.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD67491.1 - 9.2e-13 47.8 0.0 3e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMD67491.1 - 1.7e-05 24.3 10.9 1.7e-05 24.3 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EMD67491.1 - 0.00044 19.1 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.1 EMD67491.1 - 0.001 18.8 11.1 0.001 18.8 7.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD67491.1 - 0.0042 17.0 10.1 0.0042 17.0 7.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD67491.1 - 0.0046 16.6 11.3 0.0046 16.6 7.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD67491.1 - 0.0087 15.7 10.2 0.0087 15.7 7.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD67491.1 - 0.054 13.2 6.8 0.025 14.2 2.7 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.1 EMD67491.1 - 0.58 9.6 12.4 2 7.9 0.9 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Pkinase PF00069.20 EMD67492.1 - 0.00021 20.5 0.0 0.0018 17.5 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Conotoxin PF02950.12 EMD67493.1 - 0.11 13.3 0.6 0.13 13.1 0.4 1.3 1 0 0 1 1 1 0 Conotoxin DUF4013 PF13197.1 EMD67494.1 - 0.013 14.8 1.4 0.015 14.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF2892 PF11127.3 EMD67494.1 - 0.021 14.6 1.8 0.034 13.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) Yip1 PF04893.12 EMD67494.1 - 0.021 14.3 1.1 0.023 14.2 0.8 1.1 1 0 0 1 1 1 0 Yip1 domain DUF202 PF02656.10 EMD67494.1 - 0.047 13.9 0.4 0.065 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF1282 PF06930.7 EMD67494.1 - 0.057 13.0 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ABC2_membrane_2 PF12679.2 EMD67494.1 - 0.072 11.9 0.3 0.085 11.7 0.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EMD67494.1 - 0.13 11.4 1.6 0.15 11.3 1.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Rick_17kDa_Anti PF05433.10 EMD67494.1 - 2.3 7.9 5.5 9.8 5.9 3.8 2.0 1 1 0 1 1 1 0 Glycine zipper 2TM domain Radical_SAM PF04055.16 EMD67495.1 - 1.6e-17 64.2 0.0 4.5e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EMD67495.1 - 7e-12 45.2 0.0 2e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD67495.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD67495.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyltransferase PF01553.16 EMD67496.1 - 2.1e-28 98.3 0.0 3.6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EMD67497.1 - 3e-49 167.3 0.0 4.8e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Init_tRNA_PT PF04179.7 EMD67498.1 - 2.9e-156 520.8 0.0 4.1e-156 520.3 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Glyco_hydro_6 PF01341.12 EMD67499.1 - 6.3e-98 327.8 0.7 7.5e-98 327.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 MFS_2 PF13347.1 EMD67500.1 - 1.3e-11 43.5 9.1 1.3e-11 43.5 6.3 3.0 4 0 0 4 4 4 2 MFS/sugar transport protein Na_H_Exchanger PF00999.16 EMD67501.1 - 9.4e-71 238.3 34.6 1.2e-70 238.0 24.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1129 PF06570.6 EMD67501.1 - 9 5.5 9.6 6.9 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) TRAPP PF04051.11 EMD67502.1 - 5.2e-42 142.9 0.0 6.3e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Poty_PP PF08440.5 EMD67503.1 - 0.00029 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Potyviridae polyprotein Ldh_1_N PF00056.18 EMD67504.1 - 2.3e-45 153.8 0.1 3.2e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMD67504.1 - 2.4e-40 138.1 0.0 3.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMD67504.1 - 1.2e-05 24.1 0.0 2.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EMD67504.1 - 0.024 13.6 0.1 0.28 10.2 0.1 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EMD67504.1 - 0.063 12.5 0.0 1.1 8.4 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 EMD67504.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMD67504.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.18 EMD67505.1 - 1.7e-19 69.6 0.6 2.4e-19 69.1 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD67505.1 - 3.1e-11 43.2 0.1 4.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EMD67505.1 - 0.037 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 EMD67506.1 - 3.5e-35 119.9 1.4 5.6e-35 119.3 0.3 1.8 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing PXA PF02194.10 EMD67506.1 - 0.059 12.9 0.5 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 PXA domain Folliculin PF11704.3 EMD67506.1 - 0.45 10.0 2.5 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport PNP_UDP_1 PF01048.15 EMD67507.1 - 2.4e-53 180.5 0.4 3.1e-53 180.1 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_trans_1_2 PF13524.1 EMD67507.1 - 0.12 12.6 0.2 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ribosomal_S10 PF00338.17 EMD67508.1 - 4.4e-21 74.5 0.0 1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Corona_nucleoca PF00937.13 EMD67508.1 - 1.1 8.0 6.2 2.1 7.1 2.9 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Glyco_hydro_31 PF01055.21 EMD67509.1 - 4.2e-89 299.3 9.4 1.8e-88 297.3 6.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Glycos_transf_1 PF00534.15 EMD67510.1 - 2e-20 72.9 0.0 5.9e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMD67510.1 - 3.5e-10 40.1 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMD67510.1 - 0.00026 21.2 0.0 0.00061 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.27 EMD67511.1 - 4e-68 223.0 16.2 5.3e-11 41.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EMD67511.1 - 2e-24 85.5 5.1 3.3e-24 84.8 3.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EMD67511.1 - 0.00011 20.4 0.8 0.027 12.6 0.0 3.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD67511.1 - 0.0016 17.2 0.2 0.46 9.1 0.1 3.1 1 1 3 4 4 4 1 Nup133 N terminal like BBP1_C PF15272.1 EMD67511.1 - 0.025 14.1 2.0 0.039 13.4 1.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Nbas_N PF15492.1 EMD67511.1 - 0.061 12.4 0.1 4.3 6.3 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LXG PF04740.7 EMD67511.1 - 0.075 12.8 2.1 0.092 12.5 0.9 1.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF724 PF05266.9 EMD67512.1 - 0.013 15.1 1.7 0.035 13.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4201 PF13870.1 EMD67512.1 - 0.034 13.5 2.4 0.069 12.5 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Med15_fungi PF05397.7 EMD67512.1 - 0.13 12.2 0.4 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 Mediator complex subunit 15 APG6 PF04111.7 EMD67512.1 - 0.28 10.2 4.5 0.36 9.8 2.5 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EMD67512.1 - 0.36 10.8 4.9 1.2 9.1 2.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EMD67512.1 - 4 6.9 6.0 12 5.5 0.3 2.8 2 1 2 4 4 4 0 Septum formation initiator Pkinase PF00069.20 EMD67513.1 - 7.1e-07 28.6 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M13_N PF05649.8 EMD67514.1 - 4.9e-96 322.1 0.0 6.2e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EMD67514.1 - 2.7e-57 193.2 0.1 1.6e-56 190.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M13 Abhydrolase_3 PF07859.8 EMD67515.1 - 3.1e-48 164.1 0.0 4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMD67515.1 - 7.7e-18 64.4 0.0 2e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMD67515.1 - 0.00031 20.5 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD67515.1 - 0.00072 18.8 0.1 0.058 12.5 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EMD67515.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2424 PF10340.4 EMD67515.1 - 0.14 10.7 0.1 0.27 9.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EMD67516.1 - 6.5e-35 121.0 0.2 7.8e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD67516.1 - 1.8e-16 60.1 0.0 6.5e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD67516.1 - 5.1e-16 58.9 0.3 2.1e-15 56.9 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMD67516.1 - 8e-10 38.4 0.0 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EMD67516.1 - 1.6e-06 27.1 0.0 2.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.13 EMD67516.1 - 0.00013 21.3 0.0 0.0096 15.2 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EMD67516.1 - 0.00015 21.3 0.3 0.015 14.9 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EMD67516.1 - 0.00034 19.5 0.0 0.00052 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.15 EMD67516.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EMD67516.1 - 0.0016 17.4 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EMD67516.1 - 0.0026 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EMD67516.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.6 EMD67516.1 - 0.12 11.3 0.1 0.91 8.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Pro_CA PF00484.14 EMD67517.1 - 7e-25 87.8 0.0 8.5e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase TPR_10 PF13374.1 EMD67518.1 - 2.1e-88 288.0 7.8 1.2e-12 47.2 0.0 8.3 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67518.1 - 1.4e-81 268.4 16.3 1.8e-15 56.6 0.0 7.2 2 1 6 8 8 7 7 Tetratricopeptide repeat HET PF06985.6 EMD67518.1 - 1.4e-20 73.8 10.9 1.5e-17 64.0 7.2 3.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.1 EMD67518.1 - 5.3e-18 63.3 13.5 0.0098 15.6 0.0 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat NB-ARC PF00931.17 EMD67518.1 - 2.2e-16 59.5 0.1 4.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EMD67518.1 - 7.3e-13 47.6 3.3 0.45 10.8 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67518.1 - 1.3e-10 41.3 0.2 0.3 11.4 0.1 6.6 1 1 5 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMD67518.1 - 2e-10 40.1 0.6 0.27 10.9 0.0 5.2 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EMD67518.1 - 2.3e-10 39.5 13.0 2.7 8.1 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD67518.1 - 7.3e-10 38.0 7.1 1 9.0 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67518.1 - 1.2e-09 38.5 0.2 4.5 8.0 0.0 6.6 3 3 3 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMD67518.1 - 2.7e-08 33.4 0.1 38 5.1 0.0 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_22 PF13401.1 EMD67518.1 - 4.4e-08 33.3 0.0 2.1e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD67518.1 - 4.5e-08 33.2 2.8 6.6e-08 32.7 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain TPR_3 PF07720.7 EMD67518.1 - 2.8e-05 23.7 0.7 0.09 12.5 0.4 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67518.1 - 4.9e-05 22.8 5.5 12 5.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 EMD67518.1 - 7.3e-05 22.4 1.2 1e+02 3.2 0.0 6.6 7 0 0 7 7 7 0 PPR repeat Arch_ATPase PF01637.13 EMD67518.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase A2M PF00207.17 EMD67518.1 - 0.00025 20.5 0.8 1.6 8.3 0.0 4.4 1 1 3 4 4 4 1 Alpha-2-macroglobulin family NACHT PF05729.7 EMD67518.1 - 0.00035 20.2 0.1 0.001 18.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EMD67518.1 - 0.0011 19.1 0.0 0.0052 16.9 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMD67518.1 - 0.0019 17.6 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2664 PF10867.3 EMD67518.1 - 0.0039 17.7 15.3 79 3.9 0.0 7.9 6 2 3 9 9 7 0 Protein of unknown function (DUF2664) AAA_25 PF13481.1 EMD67518.1 - 0.013 14.8 0.3 0.056 12.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain TPR_6 PF13174.1 EMD67518.1 - 0.029 14.8 10.6 18 6.0 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_10 PF12846.2 EMD67518.1 - 0.03 13.7 0.1 0.3 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain DUF2518 PF10726.4 EMD67518.1 - 0.26 10.8 1.2 68 2.9 0.0 3.9 1 1 3 4 4 4 0 Protein of function (DUF2518) GP40 PF11025.3 EMD67518.1 - 0.45 10.0 6.0 23 4.5 0.1 4.2 2 1 3 5 5 5 0 Glycoprotein GP40 of Cryptosporidium F-box-like PF12937.2 EMD67519.1 - 0.00023 20.8 0.2 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like Glyco_transf_8 PF01501.15 EMD67521.1 - 6e-21 74.8 0.0 9.4e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EMD67521.1 - 0.002 17.9 0.6 0.0045 16.7 0.4 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peroxin-3 PF04882.7 EMD67522.1 - 4.3e-147 490.3 0.0 5e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF4606 PF15379.1 EMD67523.1 - 0.19 11.8 3.1 1.2 9.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Pkinase PF00069.20 EMD67524.1 - 4e-34 117.9 0.0 4.8e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67524.1 - 5.7e-22 78.0 0.0 6.6e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD67524.1 - 0.031 14.0 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCHC PF00098.18 EMD67525.1 - 5.5e-28 95.5 44.4 7.6e-07 28.7 0.2 7.3 4 2 3 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EMD67525.1 - 5.3e-12 45.2 39.9 0.0012 18.5 0.6 6.5 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EMD67525.1 - 0.00047 19.7 45.1 0.12 12.0 0.5 6.8 1 1 6 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EMD67525.1 - 0.024 14.1 1.4 0.024 14.1 1.0 6.7 1 1 6 7 7 7 0 Zinc knuckle zf-CCHC_3 PF13917.1 EMD67525.1 - 0.24 11.1 30.5 9.8 6.0 0.0 5.1 1 1 3 4 4 4 0 Zinc knuckle GMC_oxred_C PF05199.8 EMD67526.1 - 1.9e-15 57.4 0.1 3e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMD67526.1 - 5.4e-06 25.7 0.0 1.3e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DUF1659 PF07872.6 EMD67526.1 - 0.037 13.6 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) TB2_DP1_HVA22 PF03134.14 EMD67527.1 - 5e-25 87.0 7.3 9.2e-25 86.2 5.1 1.4 1 1 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.10 EMD67528.1 - 5.4e-30 103.3 0.0 1.3e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain DUF3116 PF11313.3 EMD67528.1 - 0.039 13.5 0.1 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) Cellulase PF00150.13 EMD67529.1 - 2.2e-19 69.7 2.3 3.2e-19 69.1 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cu_amine_oxid PF01179.15 EMD67530.1 - 1.3e-169 564.3 0.0 1.6e-169 564.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Mito_carr PF00153.22 EMD67530.1 - 6.7e-64 211.6 0.1 3.7e-21 74.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cu_amine_oxidN3 PF02728.11 EMD67530.1 - 3e-19 68.9 0.1 6.1e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMD67530.1 - 3.5e-13 49.4 0.0 6.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_11 PF13414.1 EMD67531.1 - 1.8e-11 43.5 1.2 4.9e-07 29.3 0.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMD67531.1 - 1.5e-08 33.9 2.8 0.00038 20.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD67531.1 - 1.1e-06 28.0 2.0 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67531.1 - 6.8e-06 26.6 1.9 0.0045 17.6 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67531.1 - 1.1e-05 25.2 0.3 0.013 15.4 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67531.1 - 7.9e-05 22.1 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67531.1 - 0.0014 18.9 0.1 0.0053 17.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67531.1 - 0.0018 18.7 4.0 0.074 13.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD67531.1 - 0.026 14.2 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD67531.1 - 0.041 14.3 1.2 4.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMD67531.1 - 0.099 13.1 2.4 0.77 10.3 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1140 PF06600.6 EMD67531.1 - 0.15 12.1 0.3 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) MARVEL PF01284.18 EMD67532.1 - 5.7e-07 29.4 12.6 8.6e-07 28.8 8.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain Potass_KdpF PF09604.5 EMD67532.1 - 0.68 9.8 3.6 2.8 7.9 2.5 2.1 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) GST_N_2 PF13409.1 EMD67533.1 - 3.1e-18 65.5 0.1 8.2e-18 64.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD67533.1 - 3e-12 46.2 0.1 9.9e-12 44.5 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD67533.1 - 4.5e-05 23.3 0.0 7.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD67533.1 - 0.00088 19.4 0.0 0.01 16.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD67533.1 - 0.0062 16.9 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RhodobacterPufX PF11511.3 EMD67534.1 - 8 5.9 7.0 0.94 8.9 1.1 2.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX FAD_binding_4 PF01565.18 EMD67535.1 - 1.6e-13 50.2 3.9 4.2e-13 48.9 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMD67535.1 - 4.6e-11 42.4 0.1 9.5e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3552 PF12072.3 EMD67536.1 - 0.00014 21.1 13.1 0.00014 21.1 9.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) Bacteriocin_IIc PF10439.4 EMD67536.1 - 0.017 15.2 6.9 0.017 15.2 4.8 3.0 2 1 1 3 3 3 0 Bacteriocin class II with double-glycine leader peptide V_ATPase_I PF01496.14 EMD67536.1 - 1.2 6.8 3.8 2.4 5.9 2.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gly-zipper_YMGG PF13441.1 EMD67536.1 - 3.5 7.2 25.3 1.5e+02 2.0 17.6 2.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.7 EMD67536.1 - 4.2 6.7 7.2 3.1 7.1 3.4 1.8 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF342 PF03961.8 EMD67537.1 - 0.04 12.3 7.9 0.088 11.2 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EMD67537.1 - 0.098 11.6 12.4 0.21 10.6 8.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EMD67537.1 - 0.6 8.9 9.4 1.2 8.0 6.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SOBP PF15279.1 EMD67537.1 - 1.5 9.1 7.4 3.1 8.1 5.1 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein TPR_MLP1_2 PF07926.7 EMD67538.1 - 0.0018 17.9 3.3 0.0044 16.7 2.3 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GAS PF13851.1 EMD67538.1 - 0.0094 15.1 3.1 0.016 14.3 2.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EMD67538.1 - 0.018 14.5 0.7 0.045 13.2 0.5 1.6 1 0 0 1 1 1 0 Septum formation initiator Viral_P18 PF04521.8 EMD67538.1 - 0.2 11.1 4.3 0.39 10.1 3.0 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Adap_comp_sub PF00928.16 EMD67539.1 - 3.8e-87 291.6 0.0 5e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMD67539.1 - 1.3e-05 24.9 0.2 2.4e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EMD67539.1 - 0.025 13.7 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain IGPD PF00475.13 EMD67541.1 - 1.9e-59 199.6 0.5 2.8e-59 199.1 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase RNA_pol_L_2 PF13656.1 EMD67542.1 - 1.1e-31 108.0 0.0 1.4e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMD67542.1 - 2.5e-11 42.5 0.0 3.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EMD67543.1 - 3.9e-07 30.4 1.0 5e-07 30.1 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EMD67543.1 - 9.7e-05 22.0 0.4 0.00021 21.0 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD67543.1 - 0.00023 21.2 0.4 0.00037 20.6 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like G10 PF01125.12 EMD67544.1 - 2.3e-63 212.1 5.8 2.5e-63 211.9 4.0 1.0 1 0 0 1 1 1 1 G10 protein DUF4448 PF14610.1 EMD67545.1 - 0.035 13.6 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Lamp PF01299.12 EMD67545.1 - 0.075 12.1 0.1 0.075 12.1 0.1 1.7 2 1 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF3377 PF11857.3 EMD67545.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ArgJ PF01960.13 EMD67546.1 - 6.3e-145 482.4 1.5 7.1e-145 482.2 1.0 1.0 1 0 0 1 1 1 1 ArgJ family WD40 PF00400.27 EMD67547.1 - 1.2e-35 120.0 0.3 2.4e-13 49.4 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 EMD67547.1 - 1.7e-08 34.2 0.0 5.6e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMD67547.1 - 1.8e-07 31.3 0.2 1.8e-07 31.3 0.1 3.7 3 1 0 3 3 3 1 AAA ATPase domain Gmad1 PF10647.4 EMD67547.1 - 4.6e-05 22.9 0.3 0.19 11.0 0.0 2.3 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EMD67547.1 - 0.00011 20.5 0.4 0.25 9.4 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 NB-ARC PF00931.17 EMD67547.1 - 0.0012 17.8 0.0 0.0028 16.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain MutS_III PF05192.13 EMD67547.1 - 0.0029 17.4 0.0 0.14 11.9 0.0 2.7 1 1 0 1 1 1 1 MutS domain III AAA PF00004.24 EMD67547.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD67547.1 - 0.0045 17.1 0.1 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain PD40 PF07676.7 EMD67547.1 - 0.0052 16.4 0.0 6.4 6.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 EMD67547.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 EMD67547.1 - 0.0064 15.5 0.3 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 KAP family P-loop domain DUF1258 PF06869.7 EMD67547.1 - 0.024 13.7 0.0 6.7 5.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) AAA_17 PF13207.1 EMD67547.1 - 0.041 14.7 0.0 0.23 12.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF1513 PF07433.6 EMD67547.1 - 0.043 12.7 0.1 4.2 6.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) AAA_30 PF13604.1 EMD67547.1 - 0.046 13.3 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EMD67547.1 - 0.049 13.2 0.1 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase TFIIIC_delta PF12657.2 EMD67547.1 - 0.092 12.4 0.2 27 4.4 0.0 3.2 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term PhoH PF02562.11 EMD67547.1 - 0.096 11.9 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 EMD67547.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain eIF2A PF08662.6 EMD67547.1 - 0.2 11.3 0.0 0.8 9.3 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Fork_head PF00250.13 EMD67548.1 - 1.8e-31 108.0 0.4 3.2e-31 107.2 0.3 1.4 1 0 0 1 1 1 1 Fork head domain DEAD PF00270.24 EMD67549.1 - 2.4e-36 124.7 0.0 4.1e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD67549.1 - 1.6e-22 79.1 0.0 1.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD67549.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMD67549.1 - 0.01 15.5 0.0 0.055 13.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain SecA_DEAD PF07517.9 EMD67549.1 - 0.086 12.1 0.1 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain CBM_1 PF00734.13 EMD67551.1 - 3.3 7.4 7.5 1 9.1 1.1 2.3 2 0 0 2 2 2 0 Fungal cellulose binding domain Pkinase PF00069.20 EMD67553.1 - 1.1e-07 31.2 0.0 2.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPMT PF05724.6 EMD67554.1 - 1.5e-29 103.0 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EMD67554.1 - 2.6e-07 30.3 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67554.1 - 4.2e-07 30.5 0.0 7.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD67554.1 - 2.3e-06 27.4 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD67554.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD67554.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD67554.1 - 2.4e-05 24.3 0.1 9.4e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD67554.1 - 0.00031 21.0 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.7 EMD67554.1 - 0.037 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein ORC2 PF04084.9 EMD67555.1 - 1.6e-102 342.7 0.0 1.9e-102 342.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1649 PF07855.7 EMD67556.1 - 5.8e-62 208.1 0.3 6.7e-62 207.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 EMD67556.1 - 0.035 13.7 0.1 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain CobD_Cbib PF03186.8 EMD67556.1 - 0.045 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein MUG113 PF13455.1 EMD67557.1 - 8.8e-31 106.2 0.1 2.9e-30 104.5 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EMD67557.1 - 8.2e-22 77.4 1.5 4.5e-21 75.1 1.0 2.1 1 1 0 1 1 1 1 T5orf172 domain zf-primase PF09329.6 EMD67557.1 - 0.074 12.6 0.4 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Primase zinc finger DUF605 PF04652.11 EMD67557.1 - 0.22 10.9 20.4 0.015 14.7 10.7 1.5 2 0 0 2 2 2 0 Vta1 like Suf PF05843.9 EMD67557.1 - 1.6 8.3 3.8 2.7 7.6 2.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cu_amine_oxid PF01179.15 EMD67558.1 - 5.8e-161 535.8 0.4 8.1e-161 535.3 0.2 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EMD67558.1 - 3.7e-06 26.9 0.0 8.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMD67558.1 - 0.0032 17.5 0.1 0.0075 16.3 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Methyltransf_8 PF05148.10 EMD67558.1 - 0.011 15.3 0.1 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Nup88 PF10168.4 EMD67559.1 - 0.032 12.0 2.1 0.044 11.6 1.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Orbi_VP5 PF00901.12 EMD67559.1 - 0.46 8.6 5.9 0.69 8.0 4.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 UPF0242 PF06785.6 EMD67559.1 - 0.55 8.8 4.6 1.4 7.4 2.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EMD67559.1 - 2.4 7.0 8.2 4.4 6.2 5.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Methyltransf_31 PF13847.1 EMD67561.1 - 9.8e-24 83.6 0.0 1.6e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD67561.1 - 1.1e-17 63.9 0.0 1.9e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMD67561.1 - 3.5e-15 56.2 0.0 7.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD67561.1 - 1.3e-14 54.4 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67561.1 - 2.3e-14 53.9 0.0 8.1e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain GFA PF04828.9 EMD67561.1 - 3.8e-14 52.3 0.9 1e-13 51.0 0.5 1.9 2 0 0 2 2 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_23 PF13489.1 EMD67561.1 - 1.7e-13 50.6 0.0 2.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD67561.1 - 9.5e-12 45.1 0.0 4.8e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD67561.1 - 4.1e-10 39.7 0.1 1.4e-09 37.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMD67561.1 - 2.1e-08 33.9 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EMD67561.1 - 3.3e-06 26.5 0.0 6.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EMD67561.1 - 0.00032 20.3 0.0 0.00074 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMD67561.1 - 0.00042 19.4 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EMD67561.1 - 0.00051 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EMD67561.1 - 0.0011 19.8 0.1 0.0045 17.7 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMD67561.1 - 0.0029 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EMD67561.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 EMD67561.1 - 0.011 15.2 0.1 0.052 13.0 0.0 2.0 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_9 PF08003.6 EMD67561.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.8 EMD67561.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 EMD67561.1 - 0.079 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF463 PF04317.7 EMD67563.1 - 0.041 12.4 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AXE1 PF05448.7 EMD67563.1 - 0.066 11.6 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SNF2_N PF00176.18 EMD67564.1 - 1e-83 280.6 0.9 1e-83 280.6 0.6 2.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EMD67564.1 - 2.6e-23 81.7 0.6 2e-22 78.8 0.2 2.8 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EMD67564.1 - 1.3e-16 60.2 2.5 8.7e-16 57.5 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 EMD67564.1 - 3.5e-16 59.1 0.7 3.5e-16 59.1 0.5 3.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EMD67564.1 - 7.4e-14 51.2 13.9 7.4e-14 51.2 9.6 3.0 3 0 0 3 3 3 1 HSA QLQ PF08880.6 EMD67564.1 - 6.6e-11 41.4 0.6 6.6e-11 41.4 0.4 2.3 2 0 0 2 2 2 1 QLQ His_biosynth PF00977.16 EMD67565.1 - 1.4e-32 112.7 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF2340 PF10209.4 EMD67565.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) TMP-TENI PF02581.12 EMD67565.1 - 0.061 12.4 0.1 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Ribul_P_3_epim PF00834.14 EMD67565.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EMD67566.1 - 6.2 6.8 32.3 0.057 13.4 13.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) Toxin_34 PF08396.5 EMD67568.1 - 0.39 11.2 2.9 1.3 9.5 2.3 1.7 1 1 1 2 2 2 0 Spider toxin omega agatoxin/Tx1 family zf-C2H2 PF00096.21 EMD67570.1 - 1.4e-21 75.4 18.2 3.3e-05 23.9 0.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD67570.1 - 6.2e-19 67.2 22.1 2.3e-08 33.9 0.3 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD67570.1 - 6.1e-15 54.3 16.2 0.0017 18.5 0.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMD67570.1 - 0.00014 21.8 8.0 0.44 10.8 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EMD67570.1 - 0.57 10.1 7.9 15 5.6 0.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMD67570.1 - 1.3 9.0 10.9 0.78 9.7 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMD67570.1 - 1.7 8.3 4.9 3 7.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EMD67570.1 - 2.3 8.4 4.8 4.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4243 PF14027.1 EMD67571.1 - 0.11 11.9 0.9 0.16 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Pmp3 PF01679.12 EMD67572.1 - 1.1 9.0 6.4 7.4 6.3 0.4 2.3 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Pro_racemase PF05544.6 EMD67575.1 - 2e-120 401.5 0.4 2.2e-120 401.3 0.3 1.0 1 0 0 1 1 1 1 Proline racemase FA_hydroxylase PF04116.8 EMD67576.1 - 2.7e-11 43.8 28.1 4.8e-11 43.0 16.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily TGS PF02824.16 EMD67577.1 - 2.1e-19 69.1 0.8 3.3e-19 68.4 0.2 1.6 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EMD67577.1 - 2.7e-19 69.2 0.1 1.5e-18 66.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD67577.1 - 3.3e-11 42.7 0.0 5.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMD67577.1 - 0.00041 20.2 0.1 0.51 10.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EMD67577.1 - 0.0014 19.1 0.0 0.004 17.6 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EMD67577.1 - 0.045 12.5 0.1 0.11 11.3 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EMD67577.1 - 0.056 12.2 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family MBOAT_2 PF13813.1 EMD67578.1 - 5.3e-20 71.2 1.9 1.4e-19 69.9 1.0 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Erf4 PF10256.4 EMD67580.1 - 1.9e-31 108.4 0.0 2.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4131 PF13567.1 EMD67581.1 - 0.33 10.3 5.5 0.21 10.9 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4203 PF13886.1 EMD67582.1 - 4.5e-39 134.0 23.7 5.9e-39 133.7 16.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) PDZ_2 PF13180.1 EMD67582.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain GSH_synth_ATP PF03917.12 EMD67583.1 - 5.5e-112 374.0 0.0 6.6e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMD67583.1 - 4.5e-36 123.1 0.0 8.1e-36 122.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Aminotran_1_2 PF00155.16 EMD67585.1 - 5.1e-83 279.0 0.0 6.6e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMD67585.1 - 1.4e-06 26.8 0.0 2.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMD67585.1 - 6.1e-06 25.2 0.1 9.9e-06 24.5 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMD67585.1 - 0.023 13.7 0.2 0.044 12.8 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tho2 PF11262.3 EMD67586.1 - 8.4e-66 222.0 0.0 1.4e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EMD67586.1 - 9.6e-24 82.9 0.1 2.1e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit MFS_1 PF07690.11 EMD67587.1 - 8.5e-32 110.2 36.5 8.5e-32 110.2 25.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily AIF-MLS PF14962.1 EMD67587.1 - 0.42 10.2 4.9 0.64 9.6 3.4 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Myb_DNA-binding PF00249.26 EMD67588.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3835 PF12927.2 EMD67588.1 - 0.041 14.8 1.9 0.041 14.8 1.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) BRE1 PF08647.6 EMD67589.1 - 8.9e-22 76.8 9.3 8.9e-22 76.8 6.4 6.6 3 2 4 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EMD67589.1 - 6.3e-09 35.7 10.4 1.1e-08 34.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD67589.1 - 1e-07 31.5 8.0 1.9e-07 30.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD67589.1 - 3.8e-07 29.6 11.6 7.3e-07 28.7 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD67589.1 - 1.9e-06 27.5 7.7 4.8e-06 26.3 5.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD67589.1 - 1.4e-05 24.6 11.2 2.7e-05 23.8 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD67589.1 - 0.0011 18.6 7.4 0.0042 16.7 5.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMD67589.1 - 0.0012 18.9 5.4 0.018 15.1 2.9 2.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EMD67589.1 - 0.0015 18.2 3.3 0.003 17.2 2.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF1272 PF06906.6 EMD67589.1 - 0.0024 17.6 6.1 0.0055 16.5 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EMD67589.1 - 0.0031 17.3 7.7 0.0061 16.4 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DZR PF12773.2 EMD67589.1 - 0.0088 15.8 7.2 0.022 14.5 5.0 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_4 PF14570.1 EMD67589.1 - 0.013 15.0 7.5 0.028 14.0 5.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2 PF00096.21 EMD67589.1 - 0.093 13.1 0.1 0.093 13.1 0.1 2.7 3 0 0 3 3 2 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.1 EMD67589.1 - 0.11 12.0 2.4 0.3 10.6 1.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prim_Zn_Ribbon PF08273.7 EMD67589.1 - 0.36 10.9 5.3 1.5 8.9 0.7 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.1 EMD67589.1 - 0.95 8.7 5.0 2.8 7.2 3.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain FYVE PF01363.16 EMD67589.1 - 0.98 9.3 10.8 4.3 7.2 4.3 2.7 1 1 1 2 2 2 0 FYVE zinc finger UPF0547 PF10571.4 EMD67589.1 - 3.7 7.3 5.9 2 8.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Reo_sigmaC PF04582.7 EMD67589.1 - 4.5 6.3 38.4 0.01 15.0 5.6 4.9 3 1 2 6 6 6 0 Reovirus sigma C capsid protein Spo12 PF05032.7 EMD67590.1 - 6.4e-13 48.0 3.9 1.4e-12 46.9 2.7 1.6 1 0 0 1 1 1 1 Spo12 family CDRT4 PF15213.1 EMD67590.1 - 1.8 8.6 4.8 2.4 8.2 0.8 2.0 1 1 1 2 2 2 0 CMT1A duplicated region transcript 4 protein UreF PF01730.11 EMD67591.1 - 5.2e-15 55.8 0.9 5.2e-15 55.8 0.6 1.6 2 0 0 2 2 2 1 UreF Lipase_GDSL_2 PF13472.1 EMD67592.1 - 9.9e-19 68.1 0.1 1.4e-18 67.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD67592.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2423 PF10338.4 EMD67593.1 - 8.2e-20 70.5 1.5 8.2e-20 70.5 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.1 EMD67594.1 - 3.3e-37 127.7 0.1 7.9e-37 126.5 0.1 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EMD67594.1 - 2.5e-19 68.5 4.2 4e-19 67.8 2.9 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMD67594.1 - 7e-07 28.6 1.3 1.4e-06 27.7 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EMD67594.1 - 1.8e-06 27.3 0.5 3.6e-06 26.3 0.3 1.6 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 EMD67594.1 - 0.014 14.9 0.2 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Peptidase_M24 PF00557.19 EMD67595.1 - 2e-46 158.1 0.1 3.8e-46 157.2 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMD67595.1 - 6.7e-05 23.4 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Pro_isomerase PF00160.16 EMD67597.1 - 8.7e-41 139.7 0.0 1.8e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MBOAT PF03062.14 EMD67598.1 - 4.5e-48 164.0 8.3 7.8e-48 163.2 5.8 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Amidase PF01425.16 EMD67600.1 - 1.7e-83 280.9 0.0 2.1e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EMD67601.1 - 2e-30 105.6 27.8 2e-30 105.6 19.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD67601.1 - 7.9e-14 51.0 2.5 7.9e-14 51.0 1.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DER1 PF04511.10 EMD67602.1 - 6.2e-47 159.6 9.0 7.8e-47 159.3 6.3 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 EMD67603.1 - 2.2e-28 98.1 0.2 3.5e-28 97.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMD67603.1 - 2.8e-06 27.3 0.1 4.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EMD67603.1 - 0.0091 15.2 0.1 0.0096 15.2 0.1 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EMD67603.1 - 0.013 15.5 0.4 0.025 14.6 0.2 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EMD67603.1 - 0.035 13.8 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EMD67603.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 Bromodomain associated Abhydrolase_6 PF12697.2 EMD67604.1 - 6.6e-13 49.0 0.7 1e-12 48.4 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD67604.1 - 3.5e-10 39.8 0.1 1.2e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EMD67604.1 - 0.00015 21.0 1.0 0.0012 18.1 0.7 2.0 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.3 EMD67604.1 - 0.0061 16.3 0.1 0.026 14.3 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMD67604.1 - 0.0068 15.6 0.7 0.73 9.0 0.3 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DDE_1 PF03184.14 EMD67605.1 - 5.7e-25 87.7 0.0 1.4e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EMD67605.1 - 0.024 14.2 0.9 0.024 14.2 0.6 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EMD67605.1 - 0.45 10.5 3.8 0.78 9.7 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Cyt-b5 PF00173.23 EMD67609.1 - 3.9e-15 55.4 0.0 2e-14 53.1 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.15 EMD67609.1 - 5e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain IDO PF01231.13 EMD67609.1 - 2.4e-10 39.4 0.0 7.1e-09 34.5 0.0 2.3 1 1 1 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 EMD67609.1 - 6.9e-09 36.2 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_S10 PF00450.17 EMD67611.1 - 7.5e-85 285.5 3.6 1.4e-84 284.6 2.5 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Laminin_I PF06008.9 EMD67612.1 - 0.0014 17.9 1.4 0.0017 17.7 0.9 1.2 1 0 0 1 1 1 1 Laminin Domain I DUF91 PF01939.11 EMD67612.1 - 0.013 14.7 0.5 0.013 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF91 CDC37_N PF03234.9 EMD67612.1 - 0.047 14.0 0.9 0.053 13.8 0.6 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Biotin_carb_C PF02785.14 EMD67612.1 - 0.08 12.9 0.2 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Biotin carboxylase C-terminal domain Tautomerase_2 PF14552.1 EMD67612.1 - 0.1 12.6 0.7 0.15 12.0 0.2 1.5 2 0 0 2 2 2 0 Tautomerase enzyme Histone_HNS PF00816.16 EMD67612.1 - 0.12 12.8 2.8 7 7.2 0.1 2.0 1 1 1 2 2 2 0 H-NS histone family VPS11_C PF12451.3 EMD67612.1 - 0.13 12.1 0.6 6.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF2870 PF11069.3 EMD67612.1 - 0.16 12.0 0.8 0.2 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) TSC22 PF01166.13 EMD67612.1 - 0.4 10.6 2.2 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.16 EMD67612.1 - 1.3 8.9 9.9 3 7.8 6.2 1.8 1 1 1 2 2 2 0 bZIP transcription factor MFS_1 PF07690.11 EMD67613.1 - 2.8e-22 78.9 44.3 4.1e-22 78.3 30.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF89 PF01937.14 EMD67614.1 - 6.6e-135 449.4 0.1 7.6e-135 449.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MFS_1 PF07690.11 EMD67616.1 - 7.9e-34 116.9 26.6 7.9e-34 116.9 18.5 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EMD67617.1 - 8e-67 225.4 0.0 1.3e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EMD67617.1 - 7e-39 133.5 16.6 7e-39 133.5 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD67617.1 - 5.8e-09 35.0 0.7 5.8e-09 35.0 0.5 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter AMP-binding_C PF13193.1 EMD67617.1 - 8.5e-08 33.0 0.0 5.7e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_2 PF13347.1 EMD67617.1 - 5.6e-05 21.7 14.9 0.00021 19.8 3.3 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EMD67617.1 - 0.0048 16.6 0.7 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 MFS_1 like family 4HBT PF03061.17 EMD67618.1 - 2.7e-07 30.6 0.0 4.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EMD67618.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ribonuclease_3 PF00636.21 EMD67619.1 - 1.1e-15 58.0 0.6 7.9e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMD67619.1 - 1.2e-13 51.1 0.0 2.8e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EMD67619.1 - 0.029 14.9 0.0 0.072 13.6 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif P5CR_dimer PF14748.1 EMD67619.1 - 0.051 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation GARS_A PF01071.14 EMD67620.1 - 9.9e-85 283.0 0.0 1.6e-84 282.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EMD67620.1 - 6.4e-37 126.0 0.0 2.8e-36 123.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EMD67620.1 - 1.2e-27 95.9 0.2 3.2e-27 94.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EMD67620.1 - 1.2e-14 54.5 0.0 3.9e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD67620.1 - 7e-09 34.8 0.0 6.6e-08 31.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMD67620.1 - 3.3e-06 26.5 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMD67620.1 - 2.9e-05 23.9 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EMD67620.1 - 3.3e-05 23.2 0.1 6.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EMD67620.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMD67620.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.5 EMD67620.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DCP1 PF06058.8 EMD67621.1 - 1.8e-21 76.4 0.0 3.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EMD67622.1 - 2.5e-16 60.3 0.1 3.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EMD67622.1 - 6.1e-05 22.6 1.1 9.7e-05 22.0 0.1 1.9 2 1 0 2 2 2 1 RhoGAP domain DUF2305 PF10230.4 EMD67623.1 - 4.9e-79 265.4 0.0 5.7e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EMD67623.1 - 4.3e-06 26.7 0.1 5.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMD67623.1 - 8.4e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EMD67623.1 - 0.00064 19.3 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMD67623.1 - 0.0011 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EMD67623.1 - 0.0045 16.3 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 EMD67623.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 EMD67623.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EMD67623.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 EMD67623.1 - 0.029 13.3 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.3 EMD67623.1 - 0.054 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AmoA PF05145.7 EMD67623.1 - 0.079 11.9 0.1 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 Putative ammonia monooxygenase AARP2CN PF08142.7 EMD67623.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Pep3_Vps18 PF05131.9 EMD67624.1 - 1.3e-48 164.1 0.0 3.7e-48 162.6 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EMD67624.1 - 4.5e-11 42.5 8.1 9e-09 35.0 0.7 3.1 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMD67624.1 - 0.00055 19.7 1.1 0.0011 18.7 0.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMD67624.1 - 0.0033 17.1 0.2 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 EMD67624.1 - 0.0091 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF1664 PF07889.7 EMD67624.1 - 0.016 14.9 2.4 0.12 12.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 EMD67624.1 - 0.068 13.1 0.3 5 7.0 0.0 2.9 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion zf-C3HC4 PF00097.20 EMD67624.1 - 0.095 12.3 0.3 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMF_DNA_bd PF12329.3 EMD67624.1 - 0.097 12.4 1.1 4.8 7.0 0.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C3HC4_2 PF13923.1 EMD67624.1 - 0.21 11.6 0.8 0.45 10.5 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EMD67624.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.6 3 0 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2175) Fib_alpha PF08702.5 EMD67624.1 - 1.1 9.3 4.8 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TPR_11 PF13414.1 EMD67625.1 - 1.1e-36 124.2 19.9 5.9e-07 29.0 0.0 10.5 8 2 3 11 11 11 6 TPR repeat TPR_2 PF07719.12 EMD67625.1 - 2.7e-29 98.6 29.8 0.0012 18.6 0.0 13.7 15 0 0 15 15 13 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMD67625.1 - 6.7e-26 90.3 29.6 0.0002 21.9 0.0 12.5 11 3 2 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMD67625.1 - 1.5e-22 78.1 24.8 0.00077 18.9 0.0 11.7 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMD67625.1 - 2.8e-22 78.4 20.0 1.1e-06 28.5 0.0 9.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMD67625.1 - 2.9e-22 78.7 21.0 7.3e-06 26.2 0.1 10.3 10 4 1 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMD67625.1 - 7.2e-22 75.9 23.7 7.3e-06 26.1 0.0 13.9 13 3 4 17 17 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD67625.1 - 1.6e-17 61.8 12.1 0.00095 18.7 0.0 10.6 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD67625.1 - 5.1e-17 60.3 21.0 0.0049 16.5 0.0 11.3 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMD67625.1 - 1.9e-16 59.2 20.6 4.5e-05 23.6 0.0 12.4 13 0 0 13 13 11 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD67625.1 - 1.2e-09 38.1 18.7 0.058 13.5 0.4 8.6 5 2 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMD67625.1 - 1.6e-09 37.1 19.6 0.41 10.9 0.0 12.0 14 0 0 14 14 12 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EMD67625.1 - 0.00095 18.7 2.8 2.8 7.3 0.1 4.4 4 0 0 4 4 4 1 Foie gras liver health family 1 TPR_9 PF13371.1 EMD67625.1 - 0.0024 17.6 13.2 0.018 14.8 0.0 7.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD67625.1 - 0.005 16.7 23.6 0.59 10.1 0.0 8.3 9 1 1 10 10 9 2 Tetratricopeptide repeat Sec8_exocyst PF04048.9 EMD67627.1 - 1.5e-47 160.7 6.1 1.9e-47 160.4 2.5 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EMD67627.1 - 2.1e-11 43.2 6.0 5.8e-11 41.8 4.1 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EMD67627.1 - 5.3e-06 24.8 3.7 1.1e-05 23.8 2.6 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 EMD67627.1 - 7.4e-05 22.5 0.5 0.0002 21.1 0.3 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Ded_cyto PF06920.8 EMD67627.1 - 0.00046 19.5 2.2 0.0005 19.4 0.4 1.9 2 0 0 2 2 2 1 Dedicator of cytokinesis COG2 PF06148.6 EMD67627.1 - 0.011 15.6 1.1 0.011 15.6 0.7 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.22 EMD67628.1 - 2.8e-27 95.6 0.0 4.3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EMD67628.1 - 1.6e-26 92.7 27.2 3.1e-26 91.8 18.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 EMD67628.1 - 2e-09 37.8 0.0 2.6e-07 30.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD67628.1 - 1.5e-06 27.7 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD67628.1 - 8.3e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMD67628.1 - 7.2e-05 22.8 0.2 0.00016 21.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD67628.1 - 7.6e-05 22.8 0.0 0.00039 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMD67628.1 - 0.00045 19.3 21.0 0.0021 17.1 14.5 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 EMD67628.1 - 0.0012 18.0 0.0 0.006 15.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EMD67628.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMD67628.1 - 0.0025 18.6 0.0 0.0052 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EMD67628.1 - 0.0038 16.6 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD67628.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMD67628.1 - 0.0068 16.3 0.0 0.02 14.7 0.0 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMD67628.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EMD67628.1 - 0.0084 15.7 0.1 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 EMD67628.1 - 0.013 14.5 0.0 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EMD67628.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EMD67628.1 - 0.016 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EMD67628.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMD67628.1 - 0.021 15.0 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMD67628.1 - 0.041 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EMD67628.1 - 0.049 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EMD67628.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD67628.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EMD67628.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMD67628.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EMD67628.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EMD67628.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 EMD67628.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EMD67628.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain APH PF01636.18 EMD67630.1 - 1.3e-16 61.0 0.1 2.4e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMD67630.1 - 8.5e-07 28.4 0.0 3.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EMD67630.1 - 1.7e-06 26.9 0.0 2.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EMD67630.1 - 0.00011 21.9 0.0 0.00036 20.1 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Cation_efflux PF01545.16 EMD67632.1 - 5e-29 101.2 1.3 7e-29 100.7 0.9 1.1 1 0 0 1 1 1 1 Cation efflux family TcpE PF12648.2 EMD67632.1 - 0.12 12.5 0.4 0.34 11.0 0.3 1.7 1 0 0 1 1 1 0 TcpE family DUF1686 PF07937.6 EMD67633.1 - 0.019 14.6 0.6 0.042 13.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) DUF872 PF05915.7 EMD67633.1 - 0.19 11.6 2.4 0.64 9.8 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DnaJ PF00226.26 EMD67635.1 - 1.3e-27 95.2 2.6 2.2e-27 94.5 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMD67635.1 - 1.6e-18 66.3 1.4 2.5e-16 59.3 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DKCLD PF08068.7 EMD67636.1 - 1.2e-28 98.8 0.1 7.2e-28 96.2 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EMD67636.1 - 4.8e-24 85.2 1.3 3.1e-21 76.0 0.2 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EMD67636.1 - 5.6e-19 67.6 0.8 1.1e-18 66.7 0.5 1.5 1 0 0 1 1 1 1 PUA domain RNase_H2-Ydr279 PF09468.5 EMD67636.1 - 0.35 10.0 10.2 0.56 9.3 7.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) MCLC PF05934.6 EMD67636.1 - 1.3 7.2 5.7 4.2 5.5 4.3 1.5 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) CDC45 PF02724.9 EMD67636.1 - 1.7 6.5 11.1 2.4 6.0 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EMD67636.1 - 5.5 6.7 16.1 8 6.2 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 EMD67636.1 - 7.2 6.2 23.0 12 5.5 15.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TENA_THI-4 PF03070.11 EMD67637.1 - 1e-13 51.5 0.0 1e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family adh_short PF00106.20 EMD67638.1 - 3.2e-14 53.1 0.1 4.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67638.1 - 1.4e-09 37.8 0.2 2e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 KR domain BAR PF03114.13 EMD67639.1 - 1.1e-58 198.4 3.7 1.4e-58 198.1 2.5 1.1 1 0 0 1 1 1 1 BAR domain tRNA-synt_1b PF00579.20 EMD67640.1 - 8.5e-67 225.3 0.0 1.1e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) UQ_con PF00179.21 EMD67641.1 - 7.5e-39 132.3 0.1 1e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NOA36 PF06524.7 EMD67641.1 - 4.7 6.3 8.2 5.7 6.1 5.7 1.1 1 0 0 1 1 1 0 NOA36 protein CorA PF01544.13 EMD67642.1 - 8.3e-47 159.6 0.0 1.1e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 EMD67643.1 - 1.8e-28 98.1 0.1 2.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 EMD67643.1 - 0.023 13.4 0.4 0.027 13.2 0.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily GPDPase_memb PF10110.4 EMD67643.1 - 0.15 11.5 0.2 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase zf-rbx1 PF12678.2 EMD67644.1 - 9e-36 121.8 13.7 1.1e-35 121.5 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMD67644.1 - 2.5e-17 62.4 10.0 3.3e-17 62.1 6.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMD67644.1 - 1.6e-07 31.0 12.3 1.1e-06 28.3 8.5 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD67644.1 - 0.00099 18.7 11.9 0.018 14.6 8.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD67644.1 - 0.0017 17.9 9.6 0.21 11.3 6.8 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD67644.1 - 0.039 13.9 8.3 0.039 13.9 5.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMD67644.1 - 0.4 10.6 9.4 2.1 8.3 6.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EMD67644.1 - 0.56 9.9 6.7 0.75 9.5 1.5 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EMD67644.1 - 0.8 9.4 12.4 8.3 6.2 8.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EMD67644.1 - 0.91 9.7 10.3 76 3.5 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMD67644.1 - 1.3 9.0 10.1 4.4 7.3 7.0 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain PNRC PF15365.1 EMD67645.1 - 0.0009 19.2 9.2 0.0009 19.2 6.4 3.9 3 2 0 3 3 3 1 Proline-rich nuclear receptor coactivator Pkinase PF00069.20 EMD67647.1 - 9.4e-69 231.4 0.0 9.4e-69 231.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67647.1 - 1.2e-54 185.1 0.0 2.5e-54 184.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMD67647.1 - 4.3e-20 71.8 0.0 4.3e-20 71.8 0.0 2.9 3 0 0 3 3 3 1 P21-Rho-binding domain PH PF00169.24 EMD67647.1 - 2e-06 27.9 0.0 3.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EMD67647.1 - 2.9e-06 26.4 0.0 4.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EMD67647.1 - 1.4e-05 25.3 0.0 4.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EMD67647.1 - 0.086 12.5 5.4 0.14 11.8 0.1 3.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family CH PF00307.26 EMD67648.1 - 4.5e-38 129.6 0.1 8.8e-20 70.7 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EMD67648.1 - 1.4e-28 98.6 2.8 4.9e-26 90.4 0.1 2.7 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EMD67648.1 - 3.2e-12 45.9 0.7 6e-08 32.2 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EMD67648.1 - 0.012 15.4 1.3 0.3 11.0 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_like PF09279.6 EMD67648.1 - 0.018 15.0 0.2 0.056 13.4 0.1 1.9 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 EMD67648.1 - 0.065 12.8 0.5 0.56 9.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF2884 PF11101.3 EMD67648.1 - 0.074 12.4 3.0 0.28 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) Sipho_Gp157 PF05565.6 EMD67648.1 - 0.093 12.3 2.7 0.079 12.5 0.4 2.0 2 0 0 2 2 2 0 Siphovirus Gp157 Baculo_PEP_C PF04513.7 EMD67648.1 - 0.097 12.5 3.3 0.19 11.5 1.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_7 PF13499.1 EMD67648.1 - 0.52 10.4 3.9 0.73 10.0 0.9 2.6 2 0 0 2 2 2 0 EF-hand domain pair Kinase-PPPase PF03618.9 EMD67649.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase DNA_pol3_delt_C PF14840.1 EMD67649.1 - 0.13 12.3 0.4 0.68 10.0 0.2 2.1 1 1 1 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term Tom7 PF08038.7 EMD67650.1 - 8.6e-20 69.9 0.1 9.9e-20 69.7 0.0 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.17 EMD67651.1 - 4.6e-32 109.4 0.0 6.5e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD67651.1 - 4.5e-18 64.9 0.0 2.4e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD67651.1 - 4.7e-15 55.1 0.0 7.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD67651.1 - 0.0027 17.4 0.1 0.15 11.8 0.1 2.2 1 1 1 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 EMD67651.1 - 0.14 12.1 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EMD67651.1 - 0.15 11.6 0.4 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.5 EMD67652.1 - 3.9e-48 162.4 0.0 4.4e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EMD67653.1 - 7.3e-35 119.8 0.4 9.2e-35 119.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family PhageP22-tail PF09251.5 EMD67653.1 - 0.034 12.4 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike Use1 PF09753.4 EMD67653.1 - 0.036 13.4 0.6 0.045 13.1 0.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Patatin PF01734.17 EMD67655.1 - 1.3e-10 41.6 0.0 3.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Asp_protease_2 PF13650.1 EMD67656.1 - 0.031 14.7 0.1 0.62 10.6 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 EMD67656.1 - 0.097 12.5 0.2 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF336 PF03928.9 EMD67657.1 - 1.6e-12 47.3 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) HATPase_c PF02518.21 EMD67658.1 - 2.4e-24 85.1 0.0 4.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD67658.1 - 9.9e-19 67.4 0.9 3.5e-18 65.6 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMD67658.1 - 5.9e-10 39.0 2.2 6.8e-10 38.8 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MazG PF03819.12 EMD67658.1 - 0.00034 20.4 0.2 0.00083 19.2 0.1 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PAS_4 PF08448.5 EMD67658.1 - 0.00042 20.3 0.1 0.053 13.5 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EMD67658.1 - 0.0013 19.0 0.0 0.0083 16.4 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.6 EMD67658.1 - 0.002 18.1 0.0 0.0057 16.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMD67658.1 - 0.074 12.8 0.0 0.31 10.8 0.0 2.2 1 0 0 1 1 1 0 PAS fold adh_short PF00106.20 EMD67659.1 - 2.2e-30 105.7 0.0 3.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67659.1 - 9.6e-29 100.8 0.0 1.1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67659.1 - 2.7e-11 43.4 0.0 5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD67659.1 - 0.00061 19.3 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMD67659.1 - 0.013 15.2 0.5 0.032 14.0 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EMD67659.1 - 0.033 13.3 0.0 0.094 11.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMD67659.1 - 0.035 12.8 0.1 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 EMD67659.1 - 0.056 13.2 0.1 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RRM_1 PF00076.17 EMD67660.1 - 9.8e-07 28.3 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD67660.1 - 0.00039 20.2 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EMD67660.1 - 0.0011 18.5 0.5 0.002 17.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 EMD67660.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMD67660.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tom5 PF10642.4 EMD67660.1 - 0.054 13.1 0.7 0.59 9.8 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Peptidase_C78 PF07910.8 EMD67661.1 - 2.9e-62 209.6 0.0 4.3e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 MAP65_ASE1 PF03999.7 EMD67661.1 - 1.6 7.2 13.9 2.5 6.5 9.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MaoC_dehydratas PF01575.14 EMD67662.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF2708 PF10917.3 EMD67663.1 - 0.44 10.3 1.5 25 4.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2708) L71 PF02448.10 EMD67663.1 - 1.4 8.7 11.2 6.2 6.7 2.1 2.5 1 1 1 2 2 2 0 L71 family Med9 PF07544.8 EMD67664.1 - 0.046 13.4 0.2 0.21 11.3 0.1 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin PF00804.20 EMD67664.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Syntaxin VWA_2 PF13519.1 EMD67665.1 - 0.021 14.9 0.0 0.065 13.3 0.0 1.6 1 1 1 2 2 2 0 von Willebrand factor type A domain CorA PF01544.13 EMD67666.1 - 0.015 14.3 9.1 0.039 12.9 3.8 3.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein PPC PF04151.10 EMD67666.1 - 0.071 14.0 0.2 8.7 7.3 0.0 2.9 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Chal_sti_synt_C PF02797.10 EMD67666.1 - 0.097 12.5 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain DUF1131 PF06572.7 EMD67666.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Cpn60_TCP1 PF00118.19 EMD67667.1 - 1.4e-119 399.8 10.7 1.6e-119 399.6 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 EMD67667.1 - 0.074 13.1 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator Cofilin_ADF PF00241.15 EMD67668.1 - 3.6e-31 107.6 0.2 4.7e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.2 EMD67669.1 - 2.4e-44 152.2 0.0 3e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 EMD67669.1 - 0.0045 16.3 0.1 0.0091 15.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Nol1_Nop2_Fmu PF01189.12 EMD67670.1 - 6.1e-100 334.2 0.0 9.8e-100 333.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EMD67670.1 - 0.0031 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EMD67670.1 - 0.0033 17.0 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HpaP PF09483.5 EMD67670.1 - 0.48 10.3 11.8 1.1 9.1 8.2 1.6 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Sugar_tr PF00083.19 EMD67671.1 - 2.5e-121 405.4 21.3 2.8e-121 405.2 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD67671.1 - 1.6e-18 66.5 25.8 1.6e-18 66.5 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.16 EMD67671.1 - 1.1 8.8 13.9 0.13 11.8 3.4 3.5 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus bZIP_2 PF07716.10 EMD67677.1 - 1.2e-09 37.7 15.8 3.1e-09 36.5 10.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMD67677.1 - 2.9e-05 23.9 18.5 9.6e-05 22.2 12.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor HemX PF04375.9 EMD67677.1 - 0.0092 14.6 3.1 0.013 14.0 2.2 1.3 1 0 0 1 1 1 1 HemX HAP1_N PF04849.8 EMD67677.1 - 0.013 14.4 8.0 0.019 13.9 5.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HAUS6_N PF14661.1 EMD67677.1 - 0.021 14.1 5.5 0.031 13.6 3.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.9 EMD67677.1 - 0.04 13.8 4.5 0.069 13.0 3.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.3 EMD67677.1 - 0.089 12.0 4.0 0.15 11.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 EMD67677.1 - 0.2 11.9 7.7 0.96 9.8 5.2 2.1 2 2 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EMD67677.1 - 0.36 10.4 11.2 0.53 9.9 7.8 1.2 1 0 0 1 1 1 0 Mnd1 family DUF3552 PF12072.3 EMD67677.1 - 0.45 9.6 14.4 0.66 9.1 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Seryl_tRNA_N PF02403.17 EMD67677.1 - 2.4 8.2 12.1 2.6 8.1 7.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EMD67677.1 - 8.2 6.0 7.9 18 4.9 5.0 1.9 1 1 0 1 1 1 0 Septum formation initiator ADH_zinc_N_2 PF13602.1 EMD67678.1 - 1e-21 78.1 0.2 3.9e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMD67678.1 - 2.9e-15 55.9 0.0 6.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD67678.1 - 2.2e-08 33.8 0.0 8.2e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMD67678.1 - 0.015 15.2 0.1 0.03 14.3 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Etmic-2 PF06670.6 EMD67678.1 - 0.034 12.8 0.4 0.047 12.3 0.3 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 AlaDh_PNT_C PF01262.16 EMD67678.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_6 PF12697.2 EMD67680.1 - 8.7e-30 104.2 0.0 1.1e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD67680.1 - 3.6e-21 75.7 0.0 2.4e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD67680.1 - 1.9e-11 43.9 0.0 3.5e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD67680.1 - 0.00062 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EMD67680.1 - 0.00086 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EMD67680.1 - 0.016 15.0 0.1 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase LCAT PF02450.10 EMD67680.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ndr PF03096.9 EMD67680.1 - 0.025 13.0 0.0 0.16 10.4 0.0 1.9 2 0 0 2 2 2 0 Ndr family Esterase PF00756.15 EMD67680.1 - 0.036 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 EMD67680.1 - 0.062 13.5 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.2 EMD67680.1 - 0.098 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.6 EMD67680.1 - 0.14 11.2 0.1 3.3 6.7 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1183 PF06682.7 EMD67681.1 - 1.2e-86 291.2 10.5 1.4e-86 290.9 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PIG-X PF08320.7 EMD67682.1 - 5.1e-56 189.2 0.0 1.1e-55 188.1 0.0 1.5 2 0 0 2 2 2 1 PIG-X / PBN1 ThiF PF00899.16 EMD67683.1 - 2.1e-16 59.9 0.1 3.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Urb2 PF10441.4 EMD67683.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family HET PF06985.6 EMD67685.1 - 1e-21 77.5 0.1 1.3e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 EMD67685.1 - 0.002 18.1 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 DUF815 PF05673.8 EMD67685.1 - 0.0056 15.6 0.0 0.0068 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF3564 PF12087.3 EMD67685.1 - 0.048 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) Tir_receptor_N PF07490.6 EMD67686.1 - 0.0029 17.2 1.3 0.0038 16.8 0.9 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus Cor1 PF04803.7 EMD67686.1 - 0.14 11.9 3.8 0.25 11.1 1.9 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DPBB_1 PF03330.13 EMD67687.1 - 1.5e-11 44.1 2.1 1.1e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMD67687.1 - 0.00054 19.6 1.2 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 1 Barwin family BNR PF02012.15 EMD67687.1 - 0.056 13.2 0.9 0.056 13.2 0.6 2.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EMD67687.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF3321 PF11968.3 EMD67688.1 - 5.8e-87 290.9 0.0 7.5e-87 290.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EMD67688.1 - 0.0026 17.4 0.0 0.0052 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 EMD67689.1 - 6.7e-19 67.6 11.4 1.5e-18 66.5 7.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EMD67689.1 - 1.6e-13 50.4 0.4 3.5e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 EMD67690.1 - 2.4e-20 71.5 0.2 4.3e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Aa_trans PF01490.13 EMD67691.1 - 2.7e-60 203.9 28.8 3.2e-60 203.7 20.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.10 EMD67692.1 - 2.3e-47 160.6 0.1 3.9e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMD67692.1 - 9.4e-40 135.4 0.3 2e-39 134.3 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EMD67692.1 - 9.2e-29 99.6 0.0 1.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 EMD67693.1 - 3.7e-64 215.6 0.0 4.8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EMD67693.1 - 3.8e-07 29.4 0.0 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain Ras PF00071.17 EMD67694.1 - 2.3e-44 150.6 0.2 4.6e-44 149.6 0.1 1.5 1 0 0 1 1 1 1 Ras family tRNA-synt_2b PF00587.20 EMD67694.1 - 2.2e-30 105.4 0.0 3.6e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Miro PF08477.8 EMD67694.1 - 1.4e-13 51.3 0.2 4.9e-13 49.6 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein Seryl_tRNA_N PF02403.17 EMD67694.1 - 1.7e-07 31.1 8.7 4.3e-07 29.9 6.0 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Arf PF00025.16 EMD67694.1 - 4.1e-07 29.4 0.0 7.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD67694.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMD67694.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 2.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMD67694.1 - 0.0018 17.7 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EMD67694.1 - 0.091 12.6 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EMD67694.1 - 2.9 6.7 8.4 6.2 5.6 5.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WAPL PF07814.8 EMD67695.1 - 1.4e-11 43.7 6.3 2.9e-11 42.7 4.4 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin PUL PF08324.6 EMD67695.1 - 0.0027 16.5 1.2 0.0047 15.7 0.4 1.8 2 0 0 2 2 2 1 PUL domain UPRTase PF14681.1 EMD67696.1 - 2.7e-82 275.0 0.0 3.6e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMD67696.1 - 3.1e-05 23.6 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EMD67696.1 - 0.095 12.4 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EMD67697.1 - 4.1e-30 103.2 0.7 5.7e-30 102.8 0.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 EMD67697.1 - 0.11 12.3 1.8 0.31 10.8 0.8 1.9 1 1 1 2 2 2 0 Cysteine-rich CPXCG zf-LITAF-like PF10601.4 EMD67697.1 - 0.12 12.2 3.0 5.2 7.0 0.2 2.3 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EMD67697.1 - 0.12 12.1 0.4 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met2 PF12907.2 EMD67697.1 - 0.12 12.3 0.4 0.12 12.3 0.3 1.8 2 0 0 2 2 2 0 Zinc-binding zf-Sec23_Sec24 PF04810.10 EMD67697.1 - 0.16 11.5 2.9 0.64 9.6 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 EMD67697.1 - 0.22 11.4 1.1 0.62 10.0 0.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMD67697.1 - 0.38 10.7 0.2 0.38 10.7 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 EMD67697.1 - 0.45 10.2 1.9 0.89 9.3 1.3 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMD67697.1 - 0.46 10.1 2.1 0.89 9.1 1.4 1.5 1 1 0 1 1 1 0 zinc-ribbon domain GTP_CH_N PF12471.3 EMD67698.1 - 2.3e-93 311.2 0.0 3.6e-93 310.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EMD67698.1 - 2.1e-17 62.9 0.0 3.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 EMD67700.1 - 7.6e-81 270.0 5.9 9e-81 269.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family HIRA_B PF09453.5 EMD67703.1 - 0.014 14.9 1.3 0.028 13.9 0.9 1.5 1 0 0 1 1 1 0 HIRA B motif p450 PF00067.17 EMD67703.1 - 0.05 12.1 0.0 0.31 9.5 0.0 2.0 2 0 0 2 2 2 0 Cytochrome P450 Ham1p_like PF01725.11 EMD67704.1 - 5.8e-53 179.0 0.0 6.5e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EMD67705.1 - 8.2e-28 97.2 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD67705.1 - 6e-16 59.3 0.3 1.9e-15 57.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD67705.1 - 1.5e-06 28.1 0.1 5.2e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EMD67705.1 - 1.3e-05 25.0 0.1 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.1 EMD67705.1 - 2.5e-05 24.3 2.7 3.5e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 EMD67705.1 - 3.9e-05 23.5 0.1 0.00022 21.0 0.1 1.9 1 1 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 EMD67705.1 - 0.00011 21.4 0.0 0.00027 20.2 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.24 EMD67705.1 - 0.00025 21.2 0.1 0.00071 19.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EMD67705.1 - 0.00075 19.2 0.5 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 NTPase Thymidylate_kin PF02223.12 EMD67705.1 - 0.0014 17.9 0.1 0.71 9.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 EMD67705.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMD67705.1 - 0.0052 16.6 0.0 0.0094 15.8 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMD67705.1 - 0.0064 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EMD67705.1 - 0.0067 15.9 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EMD67705.1 - 0.0076 16.2 0.1 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EMD67705.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin2 PF13189.1 EMD67705.1 - 0.021 14.7 0.1 0.094 12.6 0.0 2.0 1 1 1 2 2 2 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EMD67705.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EMD67705.1 - 0.034 13.7 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.6 EMD67705.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EMD67705.1 - 0.042 13.4 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD67705.1 - 0.047 13.4 0.3 0.089 12.5 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EMD67705.1 - 0.054 12.2 0.1 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 EMD67705.1 - 0.07 12.2 0.2 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 EMD67705.1 - 0.073 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EMD67705.1 - 0.098 12.0 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EMD67705.1 - 0.099 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD67705.1 - 0.4 10.1 1.6 0.32 10.4 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NAP PF00956.13 EMD67706.1 - 7.3e-87 290.5 11.2 7.3e-87 290.5 7.8 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) MotA_ExbB PF01618.11 EMD67706.1 - 0.14 11.8 0.0 0.46 10.1 0.0 1.9 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family LAP1C PF05609.7 EMD67706.1 - 2.2 6.8 7.4 0.83 8.2 2.2 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) MFS_2 PF13347.1 EMD67707.1 - 1.9e-11 43.0 13.3 1.9e-11 43.0 9.2 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EMD67707.1 - 0.00066 19.4 0.5 0.03 14.1 0.0 2.8 2 0 0 2 2 2 1 MFS_1 like family Myosin_head PF00063.16 EMD67708.1 - 2.8e-246 818.9 0.8 2.8e-246 818.9 0.5 2.1 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 EMD67708.1 - 1.2e-34 118.3 3.7 4.5e-34 116.4 2.6 2.1 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EMD67708.1 - 7.1e-13 46.9 28.6 0.00032 20.0 0.3 6.9 6 1 0 6 6 6 4 IQ calmodulin-binding motif DUF869 PF05911.6 EMD67708.1 - 0.00072 17.9 18.8 0.0013 17.1 13.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Myosin_N PF02736.14 EMD67708.1 - 0.00098 18.7 2.4 0.0022 17.6 1.7 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EMD67708.1 - 0.0018 18.4 1.3 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain GAS PF13851.1 EMD67708.1 - 0.0045 16.2 18.5 0.0045 16.2 12.8 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EMD67708.1 - 0.0098 15.7 0.9 0.0098 15.7 0.6 4.1 3 1 1 4 4 4 1 Flagella accessory protein C (FlaC) AAA_19 PF13245.1 EMD67708.1 - 0.017 14.8 0.0 0.056 13.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EMD67708.1 - 0.036 14.0 0.0 0.17 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain Tropomyosin_1 PF12718.2 EMD67708.1 - 0.4 10.5 32.2 0.27 11.0 20.6 2.1 2 0 0 2 2 1 0 Tropomyosin like 2-Hacid_dh_C PF02826.14 EMD67709.1 - 1.6e-53 180.4 0.0 3e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD67709.1 - 2.2e-34 117.7 0.1 2.9e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMD67709.1 - 2.7e-05 24.0 0.4 6e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EMD67709.1 - 0.0017 18.2 0.8 0.0028 17.5 0.1 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain G6PD_C PF02781.11 EMD67710.1 - 6.2e-136 452.0 0.0 8.4e-136 451.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EMD67710.1 - 9.8e-64 214.9 0.0 1.7e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 EMD67710.1 - 0.049 13.7 0.3 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Thioredoxin PF00085.15 EMD67712.1 - 4.3e-06 26.3 0.0 8.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EMD67712.1 - 4.9e-06 25.4 0.1 6.4e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Phosducin UAA PF08449.6 EMD67713.1 - 4.1e-10 39.0 21.0 5e-10 38.7 14.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMD67713.1 - 3.8e-09 36.3 10.1 3.8e-09 36.3 7.0 2.8 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMD67713.1 - 0.0048 16.9 5.7 0.0048 16.9 3.9 2.3 2 0 0 2 2 2 1 EamA-like transporter family Histone PF00125.19 EMD67715.1 - 2.8e-21 75.4 0.1 3.5e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMD67715.1 - 0.002 18.1 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Striatin PF08232.7 EMD67716.1 - 2.2e-37 128.3 0.9 2.2e-37 128.3 0.6 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 EMD67716.1 - 5.1e-33 111.7 19.9 8.6e-09 34.9 0.1 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat ARD PF03079.9 EMD67717.1 - 1e-48 165.2 0.2 1.3e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EMD67717.1 - 3.4e-10 39.2 0.0 5.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMD67717.1 - 1.6e-06 27.8 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMD67717.1 - 0.00054 19.4 0.0 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMD67717.1 - 0.029 13.9 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.1 EMD67717.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.7 EMD67717.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein DUF4078 PF13300.1 EMD67717.1 - 0.12 12.5 3.4 0.17 12.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) Bac_rhamnosid PF05592.6 EMD67718.1 - 3.2e-23 81.7 0.0 7.4e-21 73.9 0.0 2.5 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Laminin_G_3 PF13385.1 EMD67718.1 - 0.0063 16.7 1.0 0.0063 16.7 0.7 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF608 PF04685.8 EMD67718.1 - 0.045 12.4 0.0 0.13 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF608 MORN PF02493.15 EMD67719.1 - 3.6e-17 60.9 20.4 2.5e-05 23.7 0.5 4.7 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 EMD67719.1 - 4.6e-12 45.4 5.7 7.2e-12 44.7 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 EMD67719.1 - 9.7e-08 31.5 0.0 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EMD67719.1 - 1e-06 28.1 0.0 2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EMD67719.1 - 0.00018 21.7 0.0 0.0051 17.0 0.0 2.5 2 0 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.1 EMD67719.1 - 0.0018 18.2 7.3 0.0034 17.3 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD67719.1 - 0.11 12.2 5.9 0.21 11.3 4.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.12 EMD67720.1 - 7.2e-147 488.2 0.0 8.2e-147 488.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EMD67720.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EMD67721.1 - 1.9e-06 27.8 0.2 0.001 19.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD67721.1 - 0.0097 15.9 0.9 4.3 7.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Cation_efflux PF01545.16 EMD67722.1 - 1.8e-35 122.4 10.5 2.2e-35 122.0 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family Ribosomal_L39 PF00832.15 EMD67723.1 - 1.3e-22 79.0 9.0 1.4e-22 78.8 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EMD67723.1 - 0.12 11.8 0.9 0.14 11.6 0.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) CN_hydrolase PF00795.17 EMD67724.1 - 1.5e-15 57.0 0.0 2.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ABC1 PF03109.11 EMD67725.1 - 5.1e-36 123.2 0.0 1.3e-35 121.9 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 EMD67725.1 - 0.21 10.7 0.0 1.6 7.7 0.0 2.1 1 1 0 1 1 1 0 Protein kinase domain ASFV_J13L PF05568.6 EMD67725.1 - 6 6.3 7.3 0.29 10.6 0.3 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein CDP-OH_P_transf PF01066.16 EMD67726.1 - 9.3e-18 64.4 3.5 9.3e-18 64.4 2.4 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase STE PF02200.11 EMD67728.1 - 2e-61 204.9 0.3 3.7e-61 204.0 0.2 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EMD67728.1 - 6.8e-12 44.9 9.5 2e-06 27.8 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD67728.1 - 1.2e-09 37.7 9.6 0.0001 22.3 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD67728.1 - 1.5e-09 37.6 2.8 1.5e-09 37.6 1.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMD67728.1 - 0.00025 20.8 0.0 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD67728.1 - 0.00048 20.1 0.3 0.024 14.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF2562 PF10814.3 EMD67728.1 - 0.013 15.4 0.2 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) zf-met PF12874.2 EMD67728.1 - 0.017 15.2 1.2 0.16 12.2 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 EMD67728.1 - 0.019 15.5 0.1 0.05 14.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 EMD67728.1 - 0.03 14.4 2.6 0.054 13.6 1.8 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EMD67728.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 zinc-finger adh_short PF00106.20 EMD67729.1 - 5.9e-11 42.5 0.0 7.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67729.1 - 8.3e-07 28.8 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD67729.1 - 0.0092 16.0 0.1 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD67729.1 - 0.028 13.3 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 EMD67730.1 - 1.1e-23 82.1 14.5 2.4e-08 33.5 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat FAM176 PF14851.1 EMD67730.1 - 1.7 8.3 3.4 3.2 7.4 2.4 1.4 1 0 0 1 1 1 0 FAM176 family Tom22 PF04281.8 EMD67730.1 - 4.8 6.7 7.0 11 5.5 4.9 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SSB PF00436.20 EMD67731.1 - 5.8e-13 48.6 0.0 7.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GIDA PF01134.17 EMD67732.1 - 2.4e-155 517.2 0.0 3e-155 516.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EMD67732.1 - 1.9e-12 47.0 0.0 4.9e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EMD67732.1 - 1.5e-08 34.8 0.8 4e-08 33.3 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD67732.1 - 2.6e-08 33.3 0.9 4.4e-08 32.6 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMD67732.1 - 4.2e-05 22.6 1.5 0.12 11.2 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD67732.1 - 4.9e-05 22.3 3.0 4.9e-05 22.3 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMD67732.1 - 0.0043 15.5 1.0 0.054 11.9 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EMD67732.1 - 0.0078 16.5 0.7 0.023 15.0 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMD67732.1 - 0.028 13.9 0.1 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EMD67732.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family SMI1_KNR4 PF09346.5 EMD67733.1 - 4.7e-35 120.4 0.0 7.9e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Macro PF01661.16 EMD67735.1 - 4.8e-38 129.6 0.0 6e-21 74.5 0.0 2.7 2 0 0 2 2 2 2 Macro domain RPA_C PF08784.6 EMD67735.1 - 0.00035 20.9 0.9 0.0013 19.1 0.1 2.4 2 0 0 2 2 2 1 Replication protein A C terminal zf-C2H2_4 PF13894.1 EMD67735.1 - 4.8 7.7 21.9 1.4 9.4 0.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger F-box-like PF12937.2 EMD67736.1 - 0.016 14.9 0.8 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EMD67736.1 - 0.019 14.6 0.4 0.082 12.5 0.1 2.1 2 0 0 2 2 2 0 F-box domain Brix PF04427.13 EMD67738.1 - 1.3e-37 129.3 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 EMD67739.1 - 1.7e-71 240.4 2.3 3.5e-71 239.4 1.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EMD67739.1 - 3.7e-51 172.8 20.8 3.7e-51 172.8 14.4 4.0 3 1 0 3 3 3 1 DNA-binding domain TPT PF03151.11 EMD67739.1 - 3.1e-18 65.8 3.4 3.1e-18 65.8 2.3 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family Helicase_C PF00271.26 EMD67739.1 - 5.6e-17 61.3 0.0 1.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EamA PF00892.15 EMD67739.1 - 1.2e-05 25.3 4.7 1.2e-05 25.3 3.3 2.4 2 0 0 2 2 2 1 EamA-like transporter family zf-CHCC PF10276.4 EMD67742.1 - 0.03 14.1 0.8 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger domain DNA_RNApol_7kD PF03604.8 EMD67742.1 - 0.045 13.2 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.1 EMD67742.1 - 0.051 13.0 0.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Desulfoferrod_N PF06397.7 EMD67742.1 - 0.051 12.9 0.7 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain A2L_zn_ribbon PF08792.5 EMD67742.1 - 0.053 13.0 1.3 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain PyrI_C PF02748.10 EMD67742.1 - 0.085 12.3 0.7 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2616 PF11077.3 EMD67742.1 - 2.2 7.7 4.8 2.9 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Phosphodiest PF01663.17 EMD67743.1 - 6.4e-18 65.2 0.7 2.5e-16 59.9 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD67743.1 - 0.00011 21.5 0.0 0.00059 19.1 0.0 1.9 2 0 0 2 2 2 1 Sulfatase PigN PF04987.9 EMD67743.1 - 0.00078 18.1 6.1 0.00078 18.1 4.2 2.9 3 1 0 3 3 3 1 Phosphatidylinositolglycan class N (PIG-N) Metalloenzyme PF01676.13 EMD67743.1 - 0.002 17.5 0.1 0.0065 15.8 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EMD67743.1 - 0.13 10.6 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FUN14 PF04930.10 EMD67744.1 - 4.6e-07 30.0 3.0 2.4e-06 27.7 2.1 1.9 1 1 0 1 1 1 1 FUN14 family RIX1 PF08167.7 EMD67745.1 - 2.3e-06 27.3 1.9 0.052 13.2 0.1 4.4 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis IBN_N PF03810.14 EMD67745.1 - 0.033 14.0 0.1 0.033 14.0 0.1 3.5 3 1 1 4 4 4 0 Importin-beta N-terminal domain HD_assoc PF13286.1 EMD67745.1 - 0.035 14.3 0.9 4 7.7 0.1 4.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Peptidase_M24 PF00557.19 EMD67746.1 - 1.1e-42 146.0 0.0 2.1e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMD67746.1 - 3.9e-27 95.3 0.0 1.3e-23 83.9 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SOR_SNZ PF01680.12 EMD67747.1 - 3.8e-114 379.4 7.2 6.3e-114 378.7 5.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EMD67747.1 - 2e-09 36.9 5.4 2.7e-06 26.6 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EMD67747.1 - 0.00035 19.6 0.1 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EMD67747.1 - 0.00056 18.9 0.9 0.012 14.5 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EMD67747.1 - 0.0012 17.7 0.7 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EMD67747.1 - 0.0013 18.0 0.3 0.054 12.7 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.13 EMD67747.1 - 0.0094 14.8 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EMD67747.1 - 0.035 13.2 0.1 0.035 13.2 0.1 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.12 EMD67747.1 - 0.086 11.9 1.8 1.3 8.1 0.1 3.0 3 1 0 3 3 3 0 Thiamine monophosphate synthase/TENI MxiH PF09392.5 EMD67747.1 - 0.44 11.1 2.1 0.47 11.0 0.4 2.0 2 1 0 2 2 2 0 Type III secretion needle MxiH like Skp1 PF01466.14 EMD67748.1 - 1e-39 134.3 2.0 1.6e-39 133.7 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMD67748.1 - 1.2e-18 66.9 0.1 3.1e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EMD67748.1 - 0.16 11.9 0.8 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EMD67749.1 - 1.1e-57 195.9 22.6 1.5e-57 195.5 15.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PLDc_2 PF13091.1 EMD67750.1 - 1.7e-14 53.6 0.0 9.6e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMD67750.1 - 5.7e-06 25.9 3.5 0.61 9.9 0.0 3.7 4 0 0 4 4 4 3 Phospholipase D Active site motif Virulence_RhuM PF13310.1 EMD67750.1 - 0.097 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Virulence protein RhuM family NDUFA12 PF05071.11 EMD67751.1 - 2.8e-26 92.0 2.3 3.7e-26 91.6 1.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 EMD67751.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 NAD_binding_8 PF13450.1 EMD67752.1 - 1e-10 41.4 0.1 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD67752.1 - 3.1e-06 26.3 0.0 5.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD67752.1 - 3.2e-06 26.4 0.0 6.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMD67752.1 - 5.4e-06 26.7 0.2 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD67752.1 - 2e-05 23.6 0.7 3.2e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMD67752.1 - 3.3e-05 23.1 0.3 6e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMD67752.1 - 3.8e-05 22.9 1.2 7.9e-05 21.9 0.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD67752.1 - 0.00012 22.1 0.1 0.0065 16.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD67752.1 - 0.00013 20.5 0.5 0.00031 19.3 0.3 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EMD67752.1 - 0.0002 20.5 0.1 0.00034 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD67752.1 - 0.00028 20.8 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD67752.1 - 0.004 16.0 0.5 0.0063 15.4 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EMD67752.1 - 0.0084 14.7 0.8 0.013 14.1 0.6 1.3 1 0 0 1 1 1 1 Tryptophan halogenase IlvN PF07991.7 EMD67752.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 EMD67752.1 - 0.035 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EMD67752.1 - 0.037 13.7 0.2 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EMD67752.1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF814 PF05670.8 EMD67752.1 - 0.066 13.1 0.1 2.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF814) ABC_tran PF00005.22 EMD67753.1 - 1.8e-54 183.7 0.1 1.9e-30 105.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMD67753.1 - 1.8e-48 165.3 24.6 1.5e-29 103.2 3.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EMD67753.1 - 2.8e-09 36.5 0.5 0.063 12.4 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD67753.1 - 2.7e-08 34.1 0.0 0.024 14.5 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EMD67753.1 - 1.2e-06 29.0 0.1 0.0012 19.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMD67753.1 - 6.1e-06 25.7 0.0 0.054 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMD67753.1 - 7.4e-05 22.3 0.2 0.099 12.0 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EMD67753.1 - 0.00016 21.7 0.2 0.53 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD67753.1 - 0.00018 20.9 0.3 0.81 9.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EMD67753.1 - 0.0005 19.0 0.0 0.043 12.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EMD67753.1 - 0.00062 18.9 0.1 0.4 9.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMD67753.1 - 0.0016 17.5 0.6 0.88 8.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EMD67753.1 - 0.0022 18.4 0.3 2 8.9 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 EMD67753.1 - 0.0035 17.1 4.0 0.07 12.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMD67753.1 - 0.0041 17.0 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EMD67753.1 - 0.0046 16.6 1.0 0.81 9.3 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMD67753.1 - 0.0055 16.8 1.4 5 7.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EMD67753.1 - 0.0065 17.2 0.0 7.6 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMD67753.1 - 0.022 14.1 0.1 5.5 6.3 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EMD67753.1 - 0.023 14.1 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EMD67753.1 - 0.027 13.1 0.9 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EMD67753.1 - 0.033 14.0 0.1 2 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMD67753.1 - 0.034 13.8 0.5 0.1 12.2 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase RNA_helicase PF00910.17 EMD67753.1 - 0.055 13.6 0.1 26 5.0 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.1 EMD67753.1 - 0.066 13.5 0.1 18 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMD67753.1 - 0.1 12.8 1.0 25 5.0 0.1 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD67753.1 - 0.12 12.1 0.4 6.7 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EMD67753.1 - 0.14 11.6 3.8 3.9 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EMD67753.1 - 0.16 11.6 2.1 2 8.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 EMD67753.1 - 0.18 10.4 0.0 0.62 8.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.7 EMD67753.1 - 0.38 10.4 2.5 1.4 8.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EMD67753.1 - 0.47 10.2 5.0 8.7 6.1 0.1 3.1 3 0 0 3 3 3 0 Dynamin family CbiA PF01656.18 EMD67753.1 - 0.47 9.8 2.9 0.6 9.4 0.0 2.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain XPA_C PF05181.7 EMD67754.1 - 6.5e-26 89.6 1.9 1.4e-25 88.6 1.3 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EMD67754.1 - 0.00088 18.8 1.5 0.00088 18.8 1.0 2.3 2 0 0 2 2 2 1 XPA protein N-terminal zf-AD PF07776.10 EMD67754.1 - 0.08 12.9 0.2 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Pept_tRNA_hydro PF01195.14 EMD67755.1 - 5.2e-32 110.8 0.0 1.1e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Methyltrans_RNA PF04452.9 EMD67755.1 - 0.0034 16.5 0.6 0.0053 15.9 0.4 1.2 1 0 0 1 1 1 1 RNA methyltransferase Cut12 PF11500.3 EMD67756.1 - 1.6e-33 115.5 14.0 1.6e-33 115.5 9.7 2.9 2 1 0 2 2 2 1 Spindle pole body formation-associated protein DUF3304 PF11745.3 EMD67756.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) HGTP_anticodon2 PF12745.2 EMD67757.1 - 3.8e-75 252.5 0.1 3.8e-75 252.5 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EMD67757.1 - 5.2e-73 245.4 0.0 2.1e-37 128.6 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67757.1 - 1.9e-44 151.7 0.0 1e-17 64.0 0.0 3.9 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 EMD67757.1 - 1.1e-12 47.8 0.3 4.3e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EMD67757.1 - 1.1e-10 41.0 0.0 8.8e-10 38.1 0.0 2.3 1 1 1 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EMD67757.1 - 1.8e-07 30.3 0.0 2.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMD67757.1 - 0.0071 16.0 2.0 0.12 12.0 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Hydant_A_N PF05378.8 EMD67757.1 - 0.014 14.9 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region Spheroidin PF05541.7 EMD67759.1 - 0.065 10.8 0.0 0.078 10.5 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Arc PF03869.9 EMD67760.1 - 0.0099 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 Arc-like DNA binding domain Ytp1 PF10355.4 EMD67761.1 - 1.9e-87 292.9 18.0 1.9e-87 292.9 12.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMD67761.1 - 1.5e-32 111.2 1.0 1.5e-32 111.2 0.7 3.4 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) Swi5 PF07061.6 EMD67762.1 - 1.5e-26 91.9 0.4 1.6e-26 91.9 0.3 1.0 1 0 0 1 1 1 1 Swi5 PAZ PF02170.17 EMD67766.1 - 0.00026 20.2 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 PAZ domain SAC3_GANP PF03399.11 EMD67767.1 - 2.9e-35 121.7 1.1 4.9e-35 120.9 0.8 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMD67767.1 - 0.0021 17.8 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2841 PF11001.3 EMD67768.1 - 4.1e-22 78.3 0.2 6.7e-22 77.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 EMD67769.1 - 6.4e-83 278.3 25.5 3.1e-45 154.7 6.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD67769.1 - 7.3e-53 178.5 0.0 3.3e-30 105.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD67769.1 - 7.8e-10 38.3 1.6 0.03 13.5 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMD67769.1 - 7.9e-08 32.4 0.2 0.0032 17.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD67769.1 - 2.2e-06 27.1 0.1 0.018 14.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMD67769.1 - 3.8e-06 26.8 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EMD67769.1 - 1.1e-05 25.5 0.0 0.079 12.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EMD67769.1 - 1.6e-05 25.3 0.2 0.0022 18.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMD67769.1 - 4.9e-05 22.8 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD67769.1 - 0.00014 21.0 0.1 0.028 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EMD67769.1 - 0.0004 20.8 0.1 1.9 9.0 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 EMD67769.1 - 0.0046 16.0 0.0 2.9 6.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EMD67769.1 - 0.0046 16.7 0.8 0.44 10.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family DUP PF00674.13 EMD67769.1 - 0.012 15.5 0.2 0.054 13.4 0.2 2.1 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.1 EMD67769.1 - 0.014 15.5 0.9 1.2 9.2 0.0 3.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD67769.1 - 0.03 13.8 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 EMD67769.1 - 0.04 13.7 0.4 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EMD67769.1 - 0.061 12.2 0.0 2.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 EMD67769.1 - 0.072 13.9 0.0 14 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMD67769.1 - 0.081 12.4 1.8 4.1 6.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EMD67769.1 - 0.092 11.3 0.8 7.6 5.0 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 EMD67769.1 - 0.1 12.3 0.0 3.4 7.2 0.0 3.2 4 0 0 4 4 4 0 Archaeal ATPase AAA_10 PF12846.2 EMD67769.1 - 0.12 11.7 0.6 6.4 6.1 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain GTP_EFTU PF00009.22 EMD67769.1 - 0.14 11.5 0.2 5.4 6.4 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Glyco_transf_8 PF01501.15 EMD67770.1 - 8.4e-12 44.9 0.7 7.3e-11 41.8 0.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EMD67770.1 - 0.022 14.5 0.2 0.031 14.0 0.1 1.3 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EMD67770.1 - 0.046 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_hydro_18 PF00704.23 EMD67772.1 - 1.9e-44 152.5 0.1 2.2e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Response_reg PF00072.19 EMD67774.1 - 1.4e-22 79.7 0.1 3.1e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMD67774.1 - 1.8e-22 79.1 0.1 4.8e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EMD67774.1 - 4.9e-13 49.3 0.2 1.2e-11 44.9 0.0 3.1 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EMD67774.1 - 9.3e-11 41.7 0.0 7.8e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 EMD67774.1 - 2e-09 37.2 0.0 6.4e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EMD67774.1 - 4.1e-06 26.5 0.0 1.5e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 PAS fold RRN7 PF11781.3 EMD67775.1 - 0.32 10.5 2.2 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Gti1_Pac2 PF09729.4 EMD67776.1 - 6.4e-53 179.0 0.1 1.2e-52 178.1 0.1 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family RAI1 PF08652.6 EMD67781.1 - 1.6e-25 88.6 0.0 3.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RRM_2 PF04059.7 EMD67783.1 - 2.5e-30 104.3 0.1 4.2e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EMD67783.1 - 0.0012 18.3 0.1 0.055 13.1 0.0 3.3 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.12 EMD67783.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain FLYWCH PF04500.11 EMD67784.1 - 0.057 13.3 0.6 0.097 12.5 0.4 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Sec15 PF04091.7 EMD67786.1 - 3.3e-107 358.4 4.3 3.3e-107 358.4 3.0 2.1 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EMD67786.1 - 5.4e-06 26.3 4.5 5.4e-06 26.3 3.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EMD67786.1 - 5.1e-05 22.3 5.6 0.00012 21.0 3.9 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EMD67786.1 - 9.3e-05 22.2 4.9 9.3e-05 22.2 3.4 2.3 2 1 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 EMD67786.1 - 0.003 17.1 4.5 0.022 14.4 3.1 2.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DASH_Duo1 PF08651.5 EMD67786.1 - 0.0043 16.5 0.5 0.03 13.8 0.4 2.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 COG5 PF10392.4 EMD67786.1 - 0.024 14.5 4.3 0.026 14.4 0.9 2.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Apc5 PF12862.2 EMD67786.1 - 0.029 14.1 0.5 0.12 12.2 0.4 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Baculo_PEP_C PF04513.7 EMD67786.1 - 9.3 6.0 17.5 0.05 13.4 3.4 3.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Saccharop_dh PF03435.13 EMD67787.1 - 6.5e-130 433.5 0.0 7.3e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMD67787.1 - 1.1e-10 41.7 0.2 2.1e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMD67787.1 - 2.2e-06 27.7 0.5 3.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EMD67787.1 - 0.00055 20.3 0.3 0.0011 19.3 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMD67787.1 - 0.0072 15.7 1.1 0.04 13.2 0.1 2.5 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EMD67787.1 - 0.0094 16.1 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 EMD67787.1 - 0.019 15.4 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NmrA PF05368.8 EMD67787.1 - 0.019 14.2 0.3 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_4 PF13439.1 EMD67787.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF410 PF04190.8 EMD67788.1 - 1.5e-48 165.5 0.0 2e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF1933 PF09147.5 EMD67788.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Sybindin PF04099.7 EMD67789.1 - 9.1e-26 90.2 0.0 1.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EMD67789.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EMD67790.1 - 1e-64 218.2 0.0 2.6e-64 216.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67790.1 - 7.2e-39 133.4 0.2 1e-36 126.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMD67790.1 - 5.5e-11 41.9 0.0 9.1e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMD67790.1 - 0.0021 17.8 0.5 0.0084 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMD67794.1 - 1.4e-63 214.4 0.0 1.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67794.1 - 6.6e-29 100.7 0.0 9.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD67794.1 - 0.0031 16.6 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMD67794.1 - 0.0064 15.4 0.0 0.021 13.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EMD67794.1 - 0.016 14.9 0.3 1.1 8.9 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMD67794.1 - 0.11 11.8 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Sad1_UNC PF07738.8 EMD67795.1 - 1e-34 119.2 0.0 1.9e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1227 PF06777.6 EMD67795.1 - 0.056 13.1 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) AAA PF00004.24 EMD67797.1 - 2.3e-41 141.0 0.0 4.3e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD67797.1 - 4.8e-07 29.9 0.2 0.0002 21.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMD67797.1 - 3.1e-06 27.2 0.0 6.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMD67797.1 - 8.5e-06 25.5 0.0 2.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EMD67797.1 - 1.5e-05 24.0 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EMD67797.1 - 0.00017 21.6 0.1 0.00053 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EMD67797.1 - 0.00036 19.6 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMD67797.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMD67797.1 - 0.0018 18.2 0.4 0.0044 17.0 0.1 1.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMD67797.1 - 0.0037 18.0 0.2 0.0098 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD67797.1 - 0.0049 16.5 0.2 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EMD67797.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EMD67797.1 - 0.0073 15.7 0.4 0.014 14.8 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMD67797.1 - 0.0083 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD67797.1 - 0.0093 15.6 0.2 0.34 10.5 0.1 2.6 2 1 1 3 3 3 1 NACHT domain AAA_3 PF07726.6 EMD67797.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMD67797.1 - 0.017 15.4 0.1 0.037 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMD67797.1 - 0.018 13.7 1.3 0.036 12.8 0.0 1.9 2 1 0 2 2 2 0 TIP49 C-terminus PhoH PF02562.11 EMD67797.1 - 0.029 13.5 0.6 0.21 10.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EMD67797.1 - 0.032 13.3 0.2 0.46 9.5 0.0 2.2 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 EMD67797.1 - 0.032 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EMD67797.1 - 0.043 13.9 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EMD67797.1 - 0.048 13.2 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMD67797.1 - 0.053 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EMD67797.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 EMD67797.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMD67797.1 - 0.18 11.1 5.6 0.27 10.5 0.3 2.7 2 1 0 3 3 3 0 AAA domain UQ_con PF00179.21 EMD67798.1 - 3.8e-42 143.0 0.0 5.5e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EMD67798.1 - 9.1e-06 25.1 0.1 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EMD67798.1 - 0.064 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Esterase PF00756.15 EMD67799.1 - 1.4e-05 24.6 0.4 3.6e-05 23.3 0.2 1.7 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.23 EMD67800.1 - 1.3e-56 192.4 0.0 1.7e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD67800.1 - 3.7e-06 26.6 0.1 1.7e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_3 PF13738.1 EMD67801.1 - 1.1e-09 38.6 0.0 4.2e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD67801.1 - 0.00014 21.8 0.0 0.35 10.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD67801.1 - 0.00017 19.9 0.0 0.00033 18.9 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EMD67801.1 - 0.06 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2207 PF09972.4 EMD67802.1 - 0.0021 16.6 0.5 0.003 16.2 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RnfC_N PF13375.1 EMD67802.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RNA_pol_I_A49 PF06870.7 EMD67803.1 - 1.9e-86 290.0 0.3 2.2e-86 289.8 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Atg14 PF10186.4 EMD67803.1 - 0.24 10.2 2.3 0.54 9.1 1.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Keratin PF02422.11 EMD67804.1 - 0.018 15.0 0.7 0.023 14.6 0.5 1.3 1 0 0 1 1 1 0 Keratin DER1 PF04511.10 EMD67805.1 - 4.1e-27 94.9 2.3 4.8e-27 94.7 1.6 1.0 1 0 0 1 1 1 1 Der1-like family AzlC PF03591.9 EMD67805.1 - 0.15 11.9 3.7 0.061 13.2 0.5 1.9 2 1 0 2 2 2 0 AzlC protein LRR_1 PF00560.28 EMD67807.1 - 0.00052 19.6 6.1 96 3.6 0.0 8.5 10 0 0 10 10 10 0 Leucine Rich Repeat PH PF00169.24 EMD67807.1 - 0.033 14.3 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 PH domain LRR_6 PF13516.1 EMD67807.1 - 0.62 10.3 14.7 85 3.7 0.0 8.3 10 0 0 10 10 10 0 Leucine Rich repeat Mtp PF03821.11 EMD67808.1 - 0.061 12.7 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Pet127 PF08634.5 EMD67809.1 - 1.8e-111 371.6 0.2 2.8e-111 371.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Spore_coat_CotO PF14153.1 EMD67809.1 - 8.1 5.8 32.2 0.48 9.8 0.4 3.2 2 1 0 2 2 2 0 Spore coat protein CotO UBA_4 PF14555.1 EMD67810.1 - 0.0004 19.8 0.1 0.00086 18.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain adh_short_C2 PF13561.1 EMD67811.1 - 3.6e-31 108.7 0.1 4.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD67811.1 - 2e-29 102.6 0.6 2.4e-29 102.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67811.1 - 2.9e-12 46.6 0.2 4.1e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD67811.1 - 0.00039 19.9 0.2 0.00052 19.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMD67811.1 - 0.0048 16.6 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EMD67811.1 - 0.0062 15.7 0.0 0.0096 15.0 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_trans_4_4 PF13579.1 EMD67811.1 - 0.057 13.5 0.1 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain 3HCDH_N PF02737.13 EMD67811.1 - 0.058 13.0 1.2 0.098 12.3 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.9 EMD67812.1 - 3.7e-59 200.1 3.4 4.7e-59 199.8 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cyclin_N PF00134.18 EMD67814.1 - 2.9e-06 26.8 0.2 5.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain LIM_bind PF01803.11 EMD67814.1 - 0.0042 16.2 1.0 0.0077 15.3 0.0 1.8 2 0 0 2 2 2 1 LIM-domain binding protein MMR_HSR1 PF01926.18 EMD67815.1 - 9.5e-18 64.2 0.3 3e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD67815.1 - 3e-07 29.8 0.3 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMD67815.1 - 0.00012 21.3 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMD67815.1 - 0.0046 16.0 0.6 0.0094 15.0 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EMD67815.1 - 0.01 15.6 8.2 0.079 12.7 0.3 3.5 3 1 0 3 3 3 0 Dynamin family Miro PF08477.8 EMD67815.1 - 0.092 13.2 1.5 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein LTV PF04180.9 EMD67816.1 - 1.7e-82 278.2 25.8 1.1e-81 275.5 17.9 1.9 1 1 0 1 1 1 1 Low temperature viability protein YL1 PF05764.8 EMD67816.1 - 1.3 8.5 12.0 0.13 11.8 4.6 2.0 2 0 0 2 2 2 0 YL1 nuclear protein His_Phos_2 PF00328.17 EMD67817.1 - 3.9e-20 72.4 0.5 2.6e-17 63.1 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TcpQ PF10671.4 EMD67817.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Toxin co-regulated pilus biosynthesis protein Q PIG-P PF08510.7 EMD67818.1 - 4.5e-41 139.4 0.0 9.8e-41 138.3 0.0 1.6 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.7 EMD67818.1 - 4.2 7.7 7.7 7.2 6.9 5.4 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Acyl-CoA_dh_1 PF00441.19 EMD67819.1 - 1.6e-26 93.2 0.4 2.6e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD67819.1 - 4.1e-16 58.2 0.0 7.4e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD67819.1 - 1.1e-15 58.1 0.2 4.6e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD67819.1 - 2.6e-11 43.8 0.4 4.5e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EMD67824.1 - 7.4e-64 215.3 0.0 8.9e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67824.1 - 2.5e-24 85.7 0.0 3.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67824.1 - 3.6e-07 29.4 0.0 1.1e-06 27.8 0.0 1.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EMD67824.1 - 0.0014 18.3 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD67824.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EMD67825.1 - 4.5e-74 248.0 1.0 8e-74 247.2 0.7 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EMD67825.1 - 4.7e-49 166.8 0.1 8.8e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EMD67825.1 - 0.13 11.6 0.1 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 MIF4G domain Mg_trans_NIPA PF05653.9 EMD67826.1 - 2.4e-62 210.5 0.3 9.1e-59 198.8 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EMD67826.1 - 3e-05 24.2 0.3 3e-05 24.2 0.2 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD67826.1 - 0.0056 16.7 1.1 0.0056 16.7 0.7 3.8 3 1 0 3 3 3 1 EamA-like transporter family Peroxidase_2 PF01328.12 EMD67827.1 - 1e-40 139.3 0.1 1.2e-40 139.1 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 AftA_N PF12250.3 EMD67827.1 - 0.027 13.2 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Ank_2 PF12796.2 EMD67828.1 - 6.4e-24 84.1 1.4 2.8e-16 59.6 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD67828.1 - 1.9e-22 77.8 0.8 1.3e-08 34.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMD67828.1 - 4.6e-21 74.7 0.8 2.7e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD67828.1 - 1e-20 71.7 0.1 3.4e-08 32.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMD67828.1 - 2.1e-15 56.3 2.1 7.8e-07 29.1 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF1966 PF09260.6 EMD67828.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) NUDE_C PF04880.8 EMD67829.1 - 0.017 15.5 1.8 0.019 15.3 1.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ATP11 PF06644.6 EMD67829.1 - 0.28 10.6 2.6 0.32 10.4 1.8 1.1 1 0 0 1 1 1 0 ATP11 protein P21-Arc PF04062.9 EMD67831.1 - 1.1e-78 262.9 0.0 1.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.6 EMD67832.1 - 1.5e-17 63.3 0.0 3.6e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EMD67832.1 - 8.1e-17 61.6 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMD67832.1 - 1.3e-13 50.9 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EMD67832.1 - 7.4e-10 38.1 0.0 3e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EMD67832.1 - 2.2e-07 31.0 0.0 8.4e-05 22.6 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMD67832.1 - 5.4e-07 29.8 0.2 4.9e-06 26.7 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMD67832.1 - 8.4e-07 28.7 0.2 4.6e-06 26.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMD67832.1 - 1.5e-06 27.1 0.0 0.0098 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EMD67832.1 - 2.3e-06 27.2 0.0 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMD67832.1 - 3e-06 26.4 0.1 8.2e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EMD67832.1 - 3e-06 26.8 0.1 5.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 EMD67832.1 - 4.3e-06 26.4 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMD67832.1 - 1.6e-05 24.6 0.3 0.0014 18.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EMD67832.1 - 1.9e-05 23.7 0.0 3.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMD67832.1 - 2.5e-05 24.1 0.0 0.00011 22.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EMD67832.1 - 0.00012 21.7 0.1 0.00038 20.0 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMD67832.1 - 0.00026 20.5 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.24 EMD67832.1 - 0.00031 20.2 0.1 0.0041 16.6 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EMD67832.1 - 0.00034 19.8 0.1 0.0072 15.5 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EMD67832.1 - 0.00058 19.1 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 EMD67832.1 - 0.00088 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EMD67832.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD67832.1 - 0.0041 16.5 0.1 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMD67832.1 - 0.0067 15.8 0.3 0.39 10.0 0.2 2.7 1 1 0 1 1 1 1 AAA-like domain IstB_IS21 PF01695.12 EMD67832.1 - 0.0082 15.5 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMD67832.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMD67832.1 - 0.014 16.2 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD67832.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase TRAPPC-Trs85 PF12739.2 EMD67832.1 - 0.016 13.8 0.1 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit AAA_18 PF13238.1 EMD67832.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EMD67832.1 - 0.025 14.4 0.0 0.53 10.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMD67832.1 - 0.025 13.3 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain ABC_tran PF00005.22 EMD67832.1 - 0.034 14.4 0.0 0.083 13.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TK PF00265.13 EMD67832.1 - 0.044 13.3 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase RNA_helicase PF00910.17 EMD67832.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 EMD67832.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EMD67832.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pkinase PF00069.20 EMD67834.1 - 1.4e-63 214.4 0.0 1.6e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67834.1 - 1.7e-29 102.6 0.0 2.2e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67834.1 - 0.0035 16.3 0.0 0.013 14.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD67834.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CMAS PF02353.15 EMD67835.1 - 6.3e-37 127.1 0.3 9.1e-37 126.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EMD67835.1 - 3.6e-18 65.5 0.0 5.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD67835.1 - 6.3e-14 52.2 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD67835.1 - 2.4e-13 50.1 0.0 3.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD67835.1 - 6.2e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD67835.1 - 4.6e-10 39.8 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD67835.1 - 1.4e-07 31.0 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMD67835.1 - 1.7e-07 31.4 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD67835.1 - 7.2e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EMD67835.1 - 9e-05 22.0 0.0 0.00027 20.5 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EMD67835.1 - 0.00011 21.3 0.0 0.00025 20.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 EMD67835.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.10 EMD67835.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EMD67835.1 - 0.0019 18.2 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EMD67835.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 EMD67835.1 - 0.047 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase AA_kinase PF00696.23 EMD67837.1 - 3e-40 138.2 0.1 4.1e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EMD67837.1 - 3.5e-09 36.0 1.1 9.6e-08 31.4 0.1 2.5 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 EMD67837.1 - 1.4e-08 33.9 0.5 8.4e-08 31.5 0.1 2.2 2 0 0 2 2 2 1 ACT domain CRT10 PF08728.5 EMD67838.1 - 0.18 9.7 1.0 0.25 9.3 0.7 1.1 1 0 0 1 1 1 0 CRT10 DUF544 PF04424.8 EMD67839.1 - 5.7e-13 48.7 0.0 9.8e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EMD67840.1 - 3.9e-85 285.6 0.0 7.7e-85 284.6 0.0 1.5 2 0 0 2 2 2 1 Gcd10p family Acyl_transf_1 PF00698.16 EMD67841.1 - 0.0078 15.5 1.1 0.021 14.1 0.8 1.7 1 0 0 1 1 1 1 Acyl transferase domain Beta-lactamase PF00144.19 EMD67843.1 - 3.5e-42 144.5 0.0 4.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EMD67843.1 - 0.044 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Abhydrolase_5 PF12695.2 EMD67845.1 - 5.8e-08 32.6 0.0 9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMD67845.1 - 7.8e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMD67845.1 - 0.00026 20.2 0.1 0.0048 16.1 0.0 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMD67845.1 - 0.0041 16.5 0.0 0.013 14.9 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EMD67845.1 - 0.01 14.3 0.1 0.22 10.0 0.0 2.5 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EMD67845.1 - 0.04 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M22 PF00814.20 EMD67846.1 - 1.2e-80 270.9 0.0 1.3e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 EMD67847.1 - 7.7e-19 68.5 0.0 1.5e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EMD67847.1 - 2.5e-08 33.8 0.5 4.5e-08 33.0 0.4 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding NblA PF04485.7 EMD67847.1 - 0.032 14.0 0.0 0.48 10.3 0.1 2.6 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA EPL1 PF10513.4 EMD67848.1 - 5.6e-39 133.9 0.9 2.2e-38 132.0 0.1 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like Latarcin PF10279.4 EMD67848.1 - 0.7 10.1 6.3 0.47 10.6 1.8 2.3 2 0 0 2 2 2 0 Latarcin precursor D123 PF07065.9 EMD67850.1 - 0.075 12.0 3.3 0.1 11.6 2.3 1.2 1 0 0 1 1 1 0 D123 INTS5_N PF14837.1 EMD67850.1 - 0.081 12.3 0.5 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Ribosomal_L6e PF01159.14 EMD67850.1 - 0.77 10.0 4.6 0.45 10.7 1.8 1.6 2 0 0 2 2 2 0 Ribosomal protein L6e NYD-SP28 PF14772.1 EMD67850.1 - 1 9.4 6.7 3.5 7.7 1.8 2.5 2 1 0 2 2 2 0 Sperm tail F-box-like PF12937.2 EMD67851.1 - 0.036 13.7 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EMD67852.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 EMD67853.1 - 4.9e-23 81.6 0.0 7.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67853.1 - 1e-06 28.0 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gly_transf_sug PF04488.10 EMD67854.1 - 6.2e-20 71.5 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMD67854.1 - 0.0052 15.3 3.1 0.65 8.4 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain CopD PF05425.8 EMD67855.1 - 0.15 12.3 0.2 0.15 12.3 0.1 3.6 3 1 1 4 4 4 0 Copper resistance protein D PRA1 PF03208.14 EMD67856.1 - 1.5 8.1 9.3 2.2 7.6 6.4 1.2 1 0 0 1 1 1 0 PRA1 family protein AMPKBI PF04739.10 EMD67857.1 - 3e-28 97.6 0.9 3e-28 97.6 0.6 2.9 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain UFD1 PF03152.9 EMD67859.1 - 4.3e-73 244.2 0.0 5.3e-73 243.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.11 EMD67860.1 - 5.9e-08 32.1 0.2 1.2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 GYF domain Vfa1 PF08432.5 EMD67860.1 - 0.034 14.1 0.7 0.034 14.1 0.5 3.9 1 1 3 4 4 4 0 AAA-ATPase Vps4-associated protein 1 Transglut_prok PF09017.5 EMD67861.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Microbial transglutaminase R3H PF01424.17 EMD67862.1 - 1.5e-10 40.6 0.0 2.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EMD67862.1 - 2.5e-07 30.5 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMD67862.1 - 5e-06 26.0 0.1 1.2e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD67862.1 - 0.007 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.12 EMD67863.1 - 3.8e-29 100.8 0.3 9.7e-29 99.5 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Seryl_tRNA_N PF02403.17 EMD67863.1 - 6.5 6.8 10.4 0.72 9.8 0.2 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain P5-ATPase PF12409.3 EMD67864.1 - 3e-38 130.3 0.0 6.9e-38 129.1 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EMD67864.1 - 7.7e-30 104.4 0.0 1.7e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMD67864.1 - 1.4e-28 99.5 0.0 3e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD67864.1 - 1.7e-16 61.2 0.0 5.5e-15 56.3 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EMD67864.1 - 9.1e-05 22.0 8.9 9.1e-05 22.0 6.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EMD67864.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMD67864.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD67864.1 - 0.027 14.0 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3278 PF11683.3 EMD67864.1 - 0.89 9.5 5.4 0.87 9.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Abhydrolase_3 PF07859.8 EMD67865.1 - 1.3e-42 145.7 0.0 1.6e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD67865.1 - 0.00018 20.8 0.0 0.00034 19.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD67865.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMD67865.1 - 0.0023 16.7 0.6 0.0043 15.8 0.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2920 PF11144.3 EMD67865.1 - 0.17 10.8 0.0 1.2 8.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Sugarporin_N PF11471.3 EMD67866.1 - 0.00067 19.2 2.2 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 Maltoporin periplasmic N-terminal extension STE3 PF02076.10 EMD67867.1 - 6.1e-80 268.3 26.8 8.9e-80 267.7 18.6 1.2 1 0 0 1 1 1 1 Pheromone A receptor Pkinase PF00069.20 EMD67867.1 - 1e-57 195.2 0.0 1.5e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67867.1 - 2e-30 105.7 0.1 5.5e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EMD67867.1 - 7.8e-06 25.0 0.1 8.4e-05 21.7 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.21 EMD67867.1 - 0.00058 19.9 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain YrbL-PhoP_reg PF10707.4 EMD67867.1 - 0.00082 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EMD67867.1 - 0.028 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.14 EMD67869.1 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HET PF06985.6 EMD67870.1 - 6.4e-32 110.6 0.8 1.9e-30 105.8 0.1 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.21 EMD67872.1 - 2e-61 207.6 0.0 4.8e-61 206.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD67872.1 - 4.3e-54 183.9 0.0 2.4e-53 181.5 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EMD67872.1 - 9.9e-53 178.4 1.2 3.4e-52 176.7 0.3 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EMD67872.1 - 2.7e-49 167.9 0.0 5.7e-49 166.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMD67872.1 - 1.1e-38 132.8 3.2 1.2e-37 129.4 0.4 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMD67872.1 - 1.5e-32 111.8 0.7 4.9e-32 110.2 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMD67872.1 - 5e-21 74.5 0.0 1.6e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD67872.1 - 6e-13 49.7 0.0 2.2e-12 47.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD67872.1 - 1.7e-06 27.7 0.1 3.7e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMD67872.1 - 1.5e-05 25.1 0.0 4.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Gln-synt_N PF03951.14 EMD67872.1 - 0.072 12.6 0.1 0.38 10.3 0.0 2.2 1 1 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Abhydrolase_6 PF12697.2 EMD67873.1 - 1.5e-16 60.9 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD67873.1 - 1.4e-15 57.3 0.0 2.2e-15 56.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMD67873.1 - 1.7e-09 36.6 0.0 4.2e-06 25.4 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMD67873.1 - 3e-09 36.4 0.0 3.3e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMD67873.1 - 3.8e-07 29.8 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EMD67873.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 EMD67873.1 - 0.001 17.7 0.0 0.011 14.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 EMD67873.1 - 0.0012 18.1 0.0 0.033 13.4 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMD67873.1 - 0.0047 16.5 0.0 0.021 14.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMD67873.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMD67873.1 - 0.16 11.4 0.0 15 4.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EMD67874.1 - 5.9e-42 143.6 48.5 5.9e-42 143.6 33.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD67874.1 - 5.4e-13 48.0 15.5 5.4e-13 48.0 10.8 1.6 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EMD67875.1 - 1.1e-55 188.9 0.0 1.5e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMD67876.1 - 2.7e-16 59.9 0.5 5.2e-16 59.0 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD67876.1 - 9.4e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD67876.1 - 7.2e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMD67876.1 - 0.0031 16.8 0.1 0.82 8.8 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family Epimerase PF01370.16 EMD67876.1 - 0.072 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 EMD67877.1 - 3e-17 62.3 1.4 6e-17 61.4 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD67877.1 - 4.5e-08 32.8 0.2 1.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_4 PF13637.1 EMD67878.1 - 2.9e-15 56.3 0.5 1.8e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD67878.1 - 6.7e-15 55.2 0.0 1.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMD67878.1 - 8.8e-14 50.5 0.6 7.7e-07 28.6 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD67878.1 - 1.3e-08 34.2 0.0 0.046 13.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMD67878.1 - 4.3e-07 29.9 0.1 0.00027 21.0 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EMD67878.1 - 0.019 14.9 9.6 0.03 14.2 6.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor Exo_endo_phos_2 PF14529.1 EMD67879.1 - 0.00051 19.6 1.8 0.00086 18.9 1.2 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase p450 PF00067.17 EMD67880.1 - 2.7e-75 253.6 0.0 3.8e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMD67880.1 - 4.2e-36 124.4 0.0 6.3e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD67880.1 - 9.2e-21 74.3 0.0 3.6e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMD67880.1 - 3.3e-16 59.7 0.0 7.4e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EMD67880.1 - 0.00095 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain DUF1878 PF08963.5 EMD67880.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) ADH_N PF08240.7 EMD67882.1 - 4.4e-15 55.3 1.7 4.4e-15 55.3 1.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD67882.1 - 0.027 14.0 0.2 0.096 12.2 0.0 1.8 1 1 0 2 2 2 0 Zinc-binding dehydrogenase RNase_H PF00075.19 EMD67884.1 - 1e-05 25.8 0.1 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF3018 PF11455.3 EMD67884.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) HTH_37 PF13744.1 EMD67885.1 - 8.4e-05 22.3 0.4 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain G-gamma PF00631.17 EMD67885.1 - 0.062 13.0 0.7 0.092 12.4 0.5 1.2 1 0 0 1 1 1 0 GGL domain Phytase PF02333.10 EMD67885.1 - 0.14 10.8 0.2 0.14 10.7 0.2 1.0 1 0 0 1 1 1 0 Phytase Zn_clus PF00172.13 EMD67886.1 - 1.8 8.5 12.0 0.74 9.7 5.4 2.3 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 EMD67887.1 - 5.1e-21 74.6 0.0 9e-16 57.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family Condensation PF00668.15 EMD67887.1 - 0.0093 14.8 0.0 0.023 13.5 0.0 1.5 2 0 0 2 2 2 1 Condensation domain p450 PF00067.17 EMD67888.1 - 3.6e-69 233.4 0.0 4.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EMD67889.1 - 3.3e-08 32.9 0.0 3.7e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldo_ket_red PF00248.16 EMD67890.1 - 1.4e-45 155.2 0.0 1.6e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_psq PF05225.11 EMD67891.1 - 0.0024 17.3 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EMD67891.1 - 0.11 12.4 0.1 0.25 11.3 0.0 1.7 1 1 1 2 2 2 0 Stage III sporulation protein D FAD_binding_4 PF01565.18 EMD67894.1 - 9.2e-17 60.8 0.1 1.3e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EMD67894.1 - 0.079 12.5 0.0 5.8 6.4 0.0 2.3 2 1 0 2 2 2 0 D-arabinono-1,4-lactone oxidase polyprenyl_synt PF00348.12 EMD67895.1 - 1.7e-13 50.0 0.0 2.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_18 PF00704.23 EMD67895.1 - 4e-07 29.8 0.6 3.4e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 3Beta_HSD PF01073.14 EMD67896.1 - 0.13 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMD67897.1 - 8.7e-29 100.5 3.3 1.2e-28 100.1 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD67897.1 - 1.2e-11 44.5 1.1 2.2e-11 43.7 0.7 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD67897.1 - 8.5e-10 38.7 0.1 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_integrase PF00589.17 EMD67897.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Phage integrase family DUF2669 PF10876.3 EMD67897.1 - 0.12 12.1 0.1 0.35 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2669) Cyclin_N PF00134.18 EMD67899.1 - 8.2e-14 51.2 0.0 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMD67899.1 - 5.8e-13 49.4 0.3 1.6e-12 48.0 0.0 1.9 2 1 0 2 2 2 1 Cyclin Pkinase PF00069.20 EMD67902.1 - 2.5e-64 216.9 0.0 3.7e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD67902.1 - 1.6e-32 112.5 0.0 3.4e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD67902.1 - 0.00034 19.6 0.0 0.00089 18.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMD67902.1 - 0.0029 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD67902.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3665 PF12427.3 EMD67903.1 - 0.34 10.3 2.8 1.9 7.9 0.2 2.9 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase MAP65_ASE1 PF03999.7 EMD67903.1 - 3 6.3 6.5 0.74 8.3 1.3 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) GCFC PF07842.7 EMD67904.1 - 3.4e-60 203.7 0.9 5.1e-60 203.1 0.6 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EMD67904.1 - 7.5e-11 41.6 6.5 1.9e-10 40.3 4.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMD67904.1 - 0.00013 21.7 2.5 0.00013 21.7 1.7 2.1 1 1 0 1 1 1 1 DExH-box splicing factor binding site PilJ PF13675.1 EMD67904.1 - 0.0068 16.7 2.2 0.53 10.6 0.8 2.7 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 EMD67904.1 - 0.05 13.2 0.1 0.05 13.2 0.1 1.9 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EMD67904.1 - 0.25 11.6 2.3 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) GEMIN8 PF15348.1 EMD67905.1 - 0.6 10.1 13.7 2.3 8.1 9.5 2.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF1510 PF07423.6 EMD67905.1 - 7.8 5.8 13.6 21 4.4 9.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sod_Fe_C PF02777.13 EMD67906.1 - 5.1e-40 135.5 1.6 6.9e-40 135.1 0.3 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMD67906.1 - 5.5e-28 97.0 2.2 9.6e-28 96.2 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acetyltransf_8 PF13523.1 EMD67907.1 - 1.1e-48 164.9 0.1 1.6e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD67907.1 - 0.0011 19.1 0.2 0.0026 17.9 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Lyase_1 PF00206.15 EMD67908.1 - 3.3e-19 69.2 0.0 5.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EMD67908.1 - 4.7e-14 52.1 0.0 2.1e-13 50.0 0.0 2.2 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus CHCH PF06747.8 EMD67910.1 - 0.00031 20.5 1.1 0.00039 20.2 0.8 1.2 1 0 0 1 1 1 1 CHCH domain TMEM154 PF15102.1 EMD67912.1 - 0.065 12.9 0.2 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family zf-CCCH PF00642.19 EMD67913.1 - 0.0006 19.4 5.8 0.0006 19.4 4.0 3.3 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BSD PF03909.12 EMD67913.1 - 0.017 14.8 0.4 0.039 13.7 0.3 1.5 1 0 0 1 1 1 0 BSD domain Syntaxin_2 PF14523.1 EMD67913.1 - 0.48 10.4 2.0 0.9 9.6 0.4 2.0 2 0 0 2 2 2 0 Syntaxin-like protein zf-PHD-like PF15446.1 EMD67914.1 - 1e-72 243.0 10.8 2.1e-72 242.0 7.1 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EMD67914.1 - 3.5e-58 196.7 0.0 5.1e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD67914.1 - 2e-14 53.1 0.0 5.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMD67914.1 - 1.4e-10 40.5 0.2 2.6e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EMD67914.1 - 4.1e-07 29.5 0.2 0.033 13.8 0.0 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EMD67914.1 - 0.00017 21.1 14.5 0.001 18.7 2.5 3.4 2 2 0 2 2 2 2 PHD-finger DEAD PF00270.24 EMD67914.1 - 0.00053 19.5 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMD67914.1 - 0.0016 18.2 0.0 0.015 15.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.1 EMD67914.1 - 0.0037 16.5 4.4 0.0037 16.5 3.0 4.0 4 1 0 4 4 4 1 PHD-finger Toxin_36 PF10550.4 EMD67914.1 - 0.28 12.4 2.6 1.5 10.1 1.8 2.4 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin SpoU_methylase PF00588.14 EMD67915.1 - 1.2e-24 86.7 0.0 3.2e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EMD67915.1 - 7.9e-05 22.7 0.0 0.00038 20.5 0.0 2.0 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding L_HGMIC_fpl PF10242.4 EMD67916.1 - 2.2e-05 24.5 4.1 2.2e-05 24.5 2.9 1.6 2 1 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 EMD67916.1 - 0.18 11.5 9.8 1.5 8.5 2.9 2.8 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Ribosomal_L6e PF01159.14 EMD67917.1 - 1.7e-34 118.3 0.2 2.8e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e p450 PF00067.17 EMD67918.1 - 2.4e-56 191.2 0.0 3.3e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.13 EMD67921.1 - 4.4e-82 275.7 26.7 5.1e-82 275.5 18.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EMD67921.1 - 9.4 5.9 7.2 3.3 7.3 0.2 3.5 4 0 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Acetyltransf_1 PF00583.19 EMD67922.1 - 3.4e-14 52.6 0.0 4.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD67922.1 - 2.6e-07 30.6 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD67922.1 - 4.7e-06 26.7 0.0 8.5e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD67922.1 - 1.6e-05 25.0 0.0 2.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD67922.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EMD67922.1 - 0.083 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase INCENP_ARK-bind PF03941.10 EMD67924.1 - 5.3e-19 67.8 1.0 5.3e-19 67.8 0.7 3.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region MARVEL PF01284.18 EMD67925.1 - 3.9e-23 81.8 13.5 4.8e-23 81.5 9.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3366 PF11846.3 EMD67925.1 - 6.1 6.6 6.0 9 6.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) FYVE_2 PF02318.11 EMD67926.1 - 0.027 14.3 1.0 0.034 14.0 0.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.19 EMD67926.1 - 0.25 11.2 1.7 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-FPG_IleRS PF06827.9 EMD67926.1 - 3.5 7.3 6.3 7.9 6.2 0.9 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS SRA1 PF07304.6 EMD67927.1 - 0.0099 15.6 0.2 0.0099 15.6 0.1 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) CAP_N PF01213.14 EMD67927.1 - 0.18 11.0 1.5 0.18 11.0 1.1 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PSP1 PF04468.7 EMD67928.1 - 8.9e-25 86.4 0.1 1.7e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Troponin-I_N PF11636.3 EMD67928.1 - 0.0054 16.3 1.4 0.26 11.0 0.0 3.7 3 0 0 3 3 3 1 Troponin I residues 1-32 Ribosomal_L15e PF00827.12 EMD67930.1 - 1.6e-87 291.9 12.1 1.8e-87 291.7 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 PT PF04886.7 EMD67930.1 - 0.13 11.6 0.4 0.21 10.9 0.3 1.2 1 0 0 1 1 1 0 PT repeat DnaJ PF00226.26 EMD67931.1 - 1.4e-21 75.9 0.2 3.8e-21 74.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_43 PF04616.9 EMD67933.1 - 2.8e-28 98.8 1.3 1.9e-27 96.0 0.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MOSC_N PF03476.11 EMD67934.1 - 7e-20 70.9 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMD67934.1 - 1.8e-15 56.5 0.0 3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain GDE_C PF06202.9 EMD67936.1 - 0.0066 15.2 0.0 0.0091 14.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase PHD PF00628.24 EMD67937.1 - 3.4e-07 29.8 8.4 5.7e-07 29.1 5.8 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EMD67937.1 - 0.0019 18.4 0.0 0.006 16.8 0.0 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EMD67937.1 - 0.0035 17.4 0.5 0.0079 16.3 0.3 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMD67937.1 - 0.13 12.2 1.1 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Dicty_REP PF05086.7 EMD67937.1 - 3 5.4 3.6 5.5 4.6 2.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 5_nucleotid_C PF02872.13 EMD67938.1 - 8e-37 126.6 0.0 1.6e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMD67938.1 - 1.6e-05 24.4 0.1 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMD67938.1 - 0.0035 17.2 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Uds1 PF15456.1 EMD67939.1 - 4.2e-39 133.3 1.8 4.2e-39 133.3 1.2 7.0 6 1 1 8 8 8 4 Up-regulated During Septation Acetyltransf_2 PF00797.12 EMD67940.1 - 7.1e-39 133.8 0.0 9.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MOZ_SAS PF01853.13 EMD67941.1 - 2.4e-80 268.2 0.1 3.3e-80 267.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EMD67941.1 - 0.0066 16.1 8.0 0.0066 16.1 5.6 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 EMD67941.1 - 0.019 14.6 2.2 0.036 13.7 0.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EMD67941.1 - 5.4 6.4 7.4 1.7 8.0 1.9 2.4 2 0 0 2 2 2 0 PHD-finger Velvet PF11754.3 EMD67942.1 - 1.4e-45 155.4 0.1 1.1e-44 152.5 0.1 2.0 1 1 0 1 1 1 1 Velvet factor SOG2 PF10428.4 EMD67943.1 - 0.0029 16.3 5.2 0.0031 16.2 3.6 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein Sporozoite_P67 PF05642.6 EMD67943.1 - 1.2 6.8 14.6 1.2 6.9 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pex14_N PF04695.8 EMD67943.1 - 4.3 7.3 8.9 5.2 7.1 6.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3827 PF12877.2 EMD67943.1 - 7.2 4.5 7.7 7.7 4.4 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DNA_pol_viral_N PF00242.12 EMD67943.1 - 8 5.3 9.0 8.5 5.2 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain p450 PF00067.17 EMD67945.1 - 2.5e-43 148.2 0.0 3.5e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 EMD67948.1 - 2.1e-10 39.1 0.0 4.8e-10 37.9 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein CDC45 PF02724.9 EMD67950.1 - 1.7e-235 782.8 0.0 2.1e-235 782.5 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Acyltransferase PF01553.16 EMD67951.1 - 1.1e-11 44.3 0.0 1.7e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Glyco_hydro_76 PF03663.9 EMD67952.1 - 8.9e-122 407.0 14.8 1.2e-121 406.6 10.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1014 PF06244.7 EMD67953.1 - 5.6e-18 65.3 14.8 5.6e-18 65.3 10.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) MIP PF00230.15 EMD67954.1 - 5.8e-06 25.9 0.0 6.2e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein HET PF06985.6 EMD67956.1 - 1.4e-20 73.8 0.0 2.1e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OPT PF03169.10 EMD67957.1 - 1.1e-157 526.2 21.6 1.3e-157 526.0 14.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_C13 PF01650.13 EMD67958.1 - 1.2e-41 142.6 0.1 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family PARP PF00644.15 EMD67959.1 - 3.2e-11 43.0 0.1 1.7e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EMD67959.1 - 2e-05 24.0 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG7 PF10191.4 EMD67960.1 - 8.8e-05 20.6 0.0 0.0011 16.9 0.0 2.0 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) COG5 PF10392.4 EMD67960.1 - 0.0028 17.5 0.2 0.0061 16.5 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 BIR PF00653.16 EMD67961.1 - 8.2e-42 141.4 0.3 1.2e-19 70.5 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain ORC6 PF05460.8 EMD67961.1 - 0.055 12.5 2.7 0.086 11.9 1.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mmp37 PF09139.6 EMD67962.1 - 1.6e-119 398.8 0.0 1.9e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 AT_hook PF02178.14 EMD67963.1 - 0.061 13.0 19.4 0.27 11.0 3.8 3.9 2 0 0 2 2 2 0 AT hook motif XPG_I PF00867.13 EMD67964.1 - 2.6e-23 81.8 0.0 5.1e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMD67964.1 - 1.2e-11 44.7 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EMD67964.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing GRAB PF10375.4 EMD67965.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 GRIP-related Arf-binding domain Thg1 PF04446.7 EMD67966.1 - 2.6e-41 140.4 0.0 3.6e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EMD67966.1 - 3.5e-10 39.6 0.1 4.6e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain SurE PF01975.12 EMD67967.1 - 1.8e-27 95.9 0.5 2.4e-27 95.5 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF3328 PF11807.3 EMD67968.1 - 0.00075 19.2 3.7 0.087 12.5 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EMD67968.1 - 0.023 13.4 10.7 0.031 12.9 7.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MARVEL PF01284.18 EMD67968.1 - 1 9.1 14.1 5.5 6.8 10.0 1.8 1 1 1 2 2 2 0 Membrane-associating domain OAD_gamma PF04277.8 EMD67968.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.0 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Peptidase_C1_2 PF03051.10 EMD67969.1 - 1.8e-155 517.8 0.1 2.1e-155 517.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EMD67969.1 - 4.1e-07 30.1 0.1 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DUF4266 PF14086.1 EMD67969.1 - 0.16 12.4 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Herpes_capsid PF06112.6 EMD67969.1 - 0.22 11.5 1.8 0.35 10.8 0.3 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Thiolase_N PF00108.18 EMD67970.1 - 3.7e-93 311.3 0.6 4.8e-93 310.9 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD67970.1 - 2.6e-36 123.7 3.7 2.6e-36 123.7 0.5 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMD67970.1 - 0.00039 19.9 5.7 0.0015 18.0 1.6 2.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMD67970.1 - 0.0046 16.5 0.3 0.53 9.9 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Homeobox_KN PF05920.6 EMD67971.1 - 1.4e-16 59.9 0.0 4e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMD67971.1 - 6e-05 22.5 0.1 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EMD67971.1 - 0.0083 16.3 1.7 0.0083 16.3 1.2 6.2 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMD67971.1 - 0.015 15.4 10.6 0.56 10.3 4.3 3.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HTH_Tnp_Tc5 PF03221.11 EMD67971.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-C2H2_jaz PF12171.3 EMD67973.1 - 3.3e-07 30.2 0.4 6.6e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD67973.1 - 1.8e-06 27.8 0.3 3.2e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMD67973.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EMD67973.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger Fzo_mitofusin PF04799.8 EMD67973.1 - 0.19 11.0 2.3 0.36 10.2 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region GST_N_3 PF13417.1 EMD67974.1 - 5.7e-21 74.5 0.1 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMD67974.1 - 4e-15 55.5 0.0 8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMD67974.1 - 3.2e-10 40.0 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EMD67974.1 - 4.9e-07 29.6 0.0 1.4e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.1 EMD67974.1 - 4.6e-05 23.2 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD67974.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD67974.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_topoisoIV PF00521.15 EMD67976.1 - 1.4e-123 412.8 0.1 1.4e-123 412.8 0.1 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EMD67976.1 - 2.4e-34 118.0 4.9 6.6e-34 116.6 3.4 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EMD67976.1 - 3e-12 46.3 0.3 2.2e-11 43.5 0.0 2.6 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EMD67976.1 - 3.6e-11 42.7 0.1 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aminotran_1_2 PF00155.16 EMD67979.1 - 6.3e-62 209.6 0.0 7.5e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EMD67979.1 - 0.00043 19.0 0.0 0.00064 18.4 0.0 1.2 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.15 EMD67979.1 - 0.005 15.1 0.0 0.011 14.0 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme YuzL PF14115.1 EMD67980.1 - 0.069 13.4 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 YuzL-like protein HSP70 PF00012.15 EMD67981.1 - 5.4e-271 899.8 7.4 6.1e-271 899.6 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMD67981.1 - 6e-17 61.2 0.0 8.9e-16 57.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EMD67981.1 - 0.001 18.2 0.1 0.021 13.9 0.0 2.4 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EMD67981.1 - 0.0038 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMD67981.1 - 0.13 12.0 3.3 4.6 7.0 2.3 3.3 1 1 0 1 1 1 0 Cell division protein FtsA Sds3 PF08598.6 EMD67982.1 - 1.9e-48 164.7 13.5 1.1e-47 162.1 9.4 2.0 1 1 0 1 1 1 1 Sds3-like DUF3245 PF11595.3 EMD67982.1 - 4.9 7.4 9.1 0.93 9.7 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3128 PF11326.3 EMD67983.1 - 1.8e-28 98.4 2.6 2.8e-28 97.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF1162 PF06650.7 EMD67984.1 - 5.7e-87 291.4 0.0 6.2e-86 288.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EMD67984.1 - 1.2e-40 137.7 0.0 3.5e-40 136.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EMD67984.1 - 0.0016 18.5 0.0 0.0086 16.2 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EMD67985.1 - 3.5e-41 140.4 14.0 8.1e-41 139.3 9.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1751 PF08551.5 EMD67986.1 - 0.024 14.9 1.6 0.024 14.9 1.1 2.0 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMD67986.1 - 0.14 12.1 5.0 0.12 12.3 2.5 1.7 1 1 0 1 1 1 0 Rhomboid family Tweety PF04906.8 EMD67987.1 - 0.02 13.2 2.0 0.034 12.5 1.4 1.3 1 0 0 1 1 1 0 Tweety DUF4164 PF13747.1 EMD67987.1 - 0.027 14.5 27.7 0.21 11.7 2.2 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) GAS PF13851.1 EMD67987.1 - 0.029 13.5 21.6 0.011 14.9 9.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 EMD67987.1 - 0.037 14.3 7.4 0.42 10.9 0.7 3.3 2 1 1 3 3 3 0 Snapin/Pallidin IncA PF04156.9 EMD67987.1 - 0.047 13.2 22.2 1.5 8.3 15.6 2.4 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EMD67987.1 - 0.051 12.7 5.0 0.046 12.9 1.8 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 EMD67987.1 - 0.077 12.4 15.1 0.32 10.5 1.6 3.7 3 1 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.16 EMD67987.1 - 0.12 12.3 17.2 0.28 11.1 3.2 4.0 3 1 0 3 3 3 0 bZIP transcription factor AAA_13 PF13166.1 EMD67987.1 - 0.18 10.2 11.0 0.26 9.6 7.6 1.1 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.11 EMD67987.1 - 0.41 9.1 4.8 0.52 8.8 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BLOC1_2 PF10046.4 EMD67987.1 - 0.42 10.7 9.3 1.8 8.7 1.0 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3373 PF11853.3 EMD67987.1 - 0.46 8.9 7.3 0.27 9.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) UPF0242 PF06785.6 EMD67987.1 - 0.52 8.9 8.5 0.79 8.3 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Fib_alpha PF08702.5 EMD67987.1 - 0.56 10.3 10.5 0.18 11.8 3.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EMD67987.1 - 0.56 10.0 2.1 1 9.1 0.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 EMD67987.1 - 0.74 10.1 19.9 1.8 8.9 3.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EMD67987.1 - 0.75 9.0 10.3 0.073 12.3 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EMD67987.1 - 1.6 7.0 18.9 1.4 7.1 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WD40_alt PF14077.1 EMD67987.1 - 1.9 8.2 5.2 3.4 7.3 1.8 2.7 1 1 1 2 2 2 0 Alternative WD40 repeat motif FlaC_arch PF05377.6 EMD67987.1 - 2 8.3 11.3 6 6.8 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GvpL_GvpF PF06386.6 EMD67987.1 - 3.2 7.2 12.0 5.6 6.4 8.3 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CHD5 PF04420.9 EMD67987.1 - 3.3 7.3 6.1 1.7 8.2 2.3 2.0 1 1 0 1 1 1 0 CHD5-like protein Tnp_P_element PF12017.3 EMD67987.1 - 3.8 6.6 9.1 0.1 11.8 0.9 2.2 2 1 1 3 3 3 0 Transposase protein Uds1 PF15456.1 EMD67987.1 - 6.4 6.7 23.5 0.32 11.0 7.4 3.5 1 1 2 3 3 3 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EMD67987.1 - 7.8 6.2 21.9 1.3 8.7 3.4 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain HALZ PF02183.13 EMD67987.1 - 7.8 6.3 15.8 7.3 6.4 0.5 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3782 PF12644.2 EMD67987.1 - 8.6 6.2 6.8 1.5e+02 2.2 4.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) SlyX PF04102.7 EMD67987.1 - 9.3 6.7 10.7 2.8 8.3 0.1 3.6 2 1 1 3 3 3 0 SlyX TMF_TATA_bd PF12325.3 EMD67987.1 - 9.9 5.9 24.8 0.57 9.9 6.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.20 EMD67988.1 - 6.6e-05 22.8 0.3 0.038 13.9 0.5 3.1 2 1 0 2 2 2 1 short chain dehydrogenase DUF3762 PF12591.3 EMD67989.1 - 0.35 10.9 2.7 0.79 9.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3762) FGGY_C PF02782.11 EMD67991.1 - 9.4e-73 244.0 0.9 1.3e-72 243.5 0.6 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMD67991.1 - 1.4e-62 211.2 0.0 1.9e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain WYL PF13280.1 EMD67992.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 WYL domain DUF3328 PF11807.3 EMD67993.1 - 2.3e-38 132.0 1.7 2.7e-38 131.8 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.27 EMD67995.1 - 3.2e-55 182.1 16.6 3.8e-10 39.2 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EMD67995.1 - 5.3e-10 38.8 0.1 1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD67995.1 - 3e-08 33.1 0.1 5.8e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMD67995.1 - 6.1e-05 21.3 5.3 5.8 4.9 0.0 5.3 2 2 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMD67995.1 - 0.0003 20.3 2.0 0.21 11.0 1.1 3.4 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 EMD67995.1 - 0.015 14.0 0.6 18 3.9 0.0 4.0 1 1 1 3 3 3 0 Nup133 N terminal like DUF4414 PF14377.1 EMD67995.1 - 0.031 14.1 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) BRAP2 PF07576.7 EMD67996.1 - 5.3e-26 90.3 0.0 1.1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EMD67996.1 - 1.4e-19 69.9 5.3 4.1e-19 68.4 3.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EMD67996.1 - 2.3e-09 36.9 9.6 2.3e-09 36.9 6.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMD67996.1 - 5.1e-05 22.8 7.3 5.1e-05 22.8 5.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD67996.1 - 0.00023 20.8 6.5 0.00023 20.8 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD67996.1 - 0.00053 19.5 5.8 0.00053 19.5 4.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD67996.1 - 0.0009 19.3 4.4 0.0009 19.3 3.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD67996.1 - 0.00096 19.1 8.6 0.00096 19.1 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD67996.1 - 0.0024 17.5 5.3 0.0057 16.3 1.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMD67996.1 - 0.0071 16.1 3.9 0.019 14.8 2.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMD67996.1 - 0.011 15.4 3.1 0.011 15.4 2.1 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Urease_gamma PF00547.13 EMD67996.1 - 0.044 13.7 0.8 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Urease, gamma subunit AAA_23 PF13476.1 EMD67996.1 - 0.1 12.9 4.6 0.15 12.3 3.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EMD67996.1 - 0.11 10.9 11.0 0.15 10.4 7.7 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 EMD67996.1 - 0.41 10.7 10.4 0.72 9.9 7.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prok-RING_4 PF14447.1 EMD67996.1 - 0.77 9.3 9.1 3.6 7.1 3.2 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TMF_DNA_bd PF12329.3 EMD67996.1 - 0.99 9.2 21.6 0.69 9.7 3.3 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 EMD67996.1 - 3.8 5.8 11.8 7 4.9 8.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Drf_GBD PF06371.8 EMD67998.1 - 1.8e-19 69.8 0.9 7.4e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Mannosyl_trans2 PF04188.8 EMD68000.1 - 3.4e-68 230.5 12.9 4.8e-68 230.0 8.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Ribosomal_L7Ae PF01248.21 EMD68001.1 - 2.2e-22 78.3 0.8 3.9e-22 77.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family OCD_Mu_crystall PF02423.10 EMD68002.1 - 7.3e-09 34.8 0.0 2e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMD68002.1 - 0.026 14.6 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3437 PF11919.3 EMD68003.1 - 8.2e-33 111.9 0.0 3.2e-32 110.0 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EMD68003.1 - 0.00085 19.2 0.0 2.7 8.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EMD68003.1 - 3.8 8.1 7.6 50 4.5 0.0 5.9 8 0 0 8 8 8 0 HEAT-like repeat Prenyltransf PF01255.14 EMD68005.1 - 9.6e-85 283.2 0.1 1.4e-84 282.6 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase VirE3 PF06661.6 EMD68005.1 - 0.045 12.8 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 VirE3 Peptidase_S10 PF00450.17 EMD68007.1 - 1.1e-67 229.0 0.0 3e-67 227.6 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.27 EMD68008.1 - 9.8e-104 335.9 14.1 2.7e-14 52.4 0.0 12.8 12 0 0 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 EMD68008.1 - 3.1e-24 85.4 0.3 6.8e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD68008.1 - 3.5e-21 75.8 8.3 2.1e-19 70.0 5.7 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD68008.1 - 1.2e-11 43.5 15.6 0.043 11.9 0.6 8.4 2 2 5 8 8 8 6 Nucleoporin Nup120/160 Nbas_N PF15492.1 EMD68008.1 - 3.3e-09 36.2 4.4 1.3 8.1 0.0 7.7 3 1 5 8 8 8 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EMD68008.1 - 2.1e-07 30.4 10.4 0.4 10.4 0.0 8.2 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EMD68008.1 - 3.4e-06 26.0 3.2 1 8.0 0.6 5.8 1 1 4 6 6 6 2 Nup133 N terminal like PQQ_2 PF13360.1 EMD68008.1 - 6.2e-06 25.8 11.6 0.084 12.3 3.4 4.3 2 1 2 4 4 4 4 PQQ-like domain Apc4_WD40 PF12894.2 EMD68008.1 - 7.8e-06 25.2 0.0 1.3 8.5 0.0 5.7 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.1 EMD68008.1 - 0.038 13.9 0.6 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Proteasome_A_N PF10584.4 EMD68008.1 - 0.079 12.2 14.5 12 5.3 0.0 7.4 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Plus-3 PF03126.13 EMD68009.1 - 4.1e-27 94.3 0.0 1.1e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain TIR PF01582.15 EMD68009.1 - 0.052 12.9 2.7 0.11 11.9 1.9 1.5 1 0 0 1 1 1 0 TIR domain SOBP PF15279.1 EMD68009.1 - 4 7.7 11.2 23 5.2 0.0 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein COQ7 PF03232.8 EMD68010.1 - 2.9e-62 209.1 0.1 3.5e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EMD68010.1 - 7.9e-05 22.9 0.1 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin Lipase_GDSL PF00657.17 EMD68011.1 - 2.6e-10 40.5 6.1 7e-10 39.1 4.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMD68011.1 - 4.4e-06 26.9 2.8 6.5e-06 26.3 1.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Oxysterol_BP PF01237.13 EMD68012.1 - 1.1e-111 372.7 0.0 3.3e-111 371.2 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EMD68012.1 - 2.2e-39 133.3 0.1 5.8e-39 132.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMD68012.1 - 0.00012 22.1 0.3 0.00037 20.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMD68012.1 - 0.0056 16.9 0.7 0.027 14.7 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain Mucin PF01456.12 EMD68012.1 - 5.2 6.8 13.1 11 5.7 4.0 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein AAA_16 PF13191.1 EMD68013.1 - 2.1e-09 37.6 0.0 2.5e-08 34.1 0.0 2.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.1 EMD68013.1 - 2.5e-09 36.9 26.2 0.037 13.9 0.1 10.0 10 1 1 11 11 10 3 Tetratricopeptide repeat NACHT PF05729.7 EMD68013.1 - 4.9e-08 32.7 0.1 4.2e-07 29.7 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EMD68013.1 - 1.3e-06 28.5 0.5 5.6e-05 23.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA PF00004.24 EMD68013.1 - 0.00016 21.8 0.2 0.0039 17.3 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.1 EMD68013.1 - 0.00048 19.9 2.7 2.4 8.1 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_17 PF13207.1 EMD68013.1 - 0.00067 20.4 0.0 0.0025 18.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD68013.1 - 0.0021 17.7 0.0 0.0078 15.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EMD68013.1 - 0.0027 17.1 0.0 0.01 15.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EMD68013.1 - 0.011 15.1 7.2 0.13 11.6 0.0 4.4 3 2 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 EMD68013.1 - 0.013 15.1 2.2 0.78 9.3 0.0 3.5 4 0 0 4 4 3 0 Uncharacterised P-loop hydrolase UPF0079 TPR_7 PF13176.1 EMD68013.1 - 0.021 14.5 15.3 22 5.1 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat AAA_18 PF13238.1 EMD68013.1 - 0.041 14.1 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.1 EMD68013.1 - 0.13 12.2 1.1 5.1 7.1 0.0 3.9 4 0 0 4 4 4 0 PPR repeat family AAA_23 PF13476.1 EMD68013.1 - 0.13 12.5 0.1 0.13 12.5 0.1 4.0 4 1 0 4 4 4 0 AAA domain Aldolase_II PF00596.16 EMD68015.1 - 1.4e-47 161.6 0.1 1.8e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain His_Phos_1 PF00300.17 EMD68017.1 - 3.1e-08 33.8 0.4 1.2e-07 31.8 0.1 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) WWbp PF10349.4 EMD68018.1 - 4e-20 72.8 4.8 4.9e-19 69.3 1.0 2.2 2 0 0 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EMD68018.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DUF883 PF05957.8 EMD68018.1 - 0.022 15.1 0.1 5.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Vps36_ESCRT-II PF11605.3 EMD68018.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Thiolase_N PF00108.18 EMD68019.1 - 3.1e-76 255.8 4.0 3.1e-76 255.8 2.8 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMD68019.1 - 7.5e-45 151.3 0.6 1.5e-44 150.3 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMD68019.1 - 0.022 14.4 0.4 9.7 5.9 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4129 PF13559.1 EMD68020.1 - 0.055 13.4 0.3 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Glyco_hydro_47 PF01532.15 EMD68021.1 - 4.1e-77 259.7 0.6 4.5e-77 259.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EMD68021.1 - 0.0061 14.8 0.0 1.5 7.0 0.0 2.3 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) LRR_6 PF13516.1 EMD68021.1 - 0.12 12.5 0.3 30 5.1 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat TBP PF00352.16 EMD68022.1 - 5.6e-68 224.3 0.1 2.2e-34 116.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMD68022.1 - 0.00018 21.5 0.0 0.57 10.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) zf-RING_2 PF13639.1 EMD68024.1 - 1.6e-10 40.6 4.3 1.6e-10 40.6 3.0 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMD68024.1 - 2.2e-08 33.9 4.3 2.2e-08 33.9 3.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD68024.1 - 2e-07 30.5 3.2 2e-07 30.5 2.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD68024.1 - 6.6e-07 28.9 5.5 6.6e-07 28.9 3.8 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMD68024.1 - 8.9e-07 28.9 12.8 2.3e-05 24.3 8.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMD68024.1 - 4.9e-06 26.1 19.0 0.00022 20.8 12.5 2.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD68024.1 - 5.1e-06 26.1 1.1 5.1e-06 26.1 0.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMD68024.1 - 0.00012 21.7 1.0 0.00012 21.7 0.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMD68024.1 - 0.00018 21.0 2.9 0.00018 21.0 2.0 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMD68024.1 - 0.00034 20.4 2.7 0.00034 20.4 1.9 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMD68024.1 - 0.00045 19.6 0.5 0.00045 19.6 0.3 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EMD68024.1 - 0.022 14.6 1.1 0.022 14.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 EMD68024.1 - 1.2 9.0 8.3 2 8.2 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-P11 PF03854.9 EMD68024.1 - 1.3 8.5 7.5 0.17 11.3 1.1 2.3 2 0 0 2 2 2 0 P-11 zinc finger Cript PF10235.4 EMD68024.1 - 2.9 8.3 9.7 0.45 10.8 2.2 2.2 1 1 0 2 2 2 0 Microtubule-associated protein CRIPT C1_4 PF07975.7 EMD68024.1 - 4.1 7.4 10.6 0.21 11.6 1.9 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain Prim_Zn_Ribbon PF08273.7 EMD68024.1 - 5.5 7.1 7.9 13 5.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-MIZ PF02891.15 EMD68024.1 - 5.5 6.5 17.6 0.1 12.1 2.6 3.0 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 EMD68025.1 - 4.1e-06 26.5 7.5 7e-06 25.7 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD68025.1 - 0.00052 20.0 4.1 0.0024 17.9 3.4 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMD68025.1 - 0.093 12.4 4.9 0.19 11.5 3.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD68025.1 - 0.19 11.3 6.0 0.41 10.3 4.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD68025.1 - 0.28 11.0 2.5 0.5 10.2 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EMD68025.1 - 0.29 10.8 7.7 1.9 8.2 5.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD68025.1 - 0.37 10.8 7.1 0.075 13.0 2.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 EMD68025.1 - 0.61 9.6 7.5 5.1 6.6 1.9 2.2 2 0 0 2 2 2 0 P-11 zinc finger MRC1 PF09444.5 EMD68026.1 - 2e-26 93.0 21.2 2e-26 93.0 14.7 7.5 7 1 2 9 9 9 1 MRC1-like domain Mut7-C PF01927.11 EMD68027.1 - 0.0016 18.4 0.9 0.0016 18.4 0.6 2.0 1 1 1 2 2 2 1 Mut7-C RNAse domain zf-FCS PF06467.9 EMD68027.1 - 0.29 10.8 4.0 0.61 9.7 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HypA PF01155.14 EMD68027.1 - 0.54 9.9 2.8 1.2 8.8 2.0 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-Di19 PF05605.7 EMD68027.1 - 9.1 6.4 11.2 2.5 8.2 3.3 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PDGLE PF13190.1 EMD68028.1 - 0.0066 16.1 0.0 0.055 13.1 0.0 2.3 2 0 0 2 2 2 1 PDGLE domain MH2 PF03166.9 EMD68029.1 - 0.00032 20.5 0.1 0.00054 19.8 0.1 1.3 1 0 0 1 1 1 1 MH2 domain Aa_trans PF01490.13 EMD68030.1 - 1.4e-24 86.3 31.1 1.6e-24 86.1 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GP41 PF00517.12 EMD68030.1 - 1.2 8.7 3.9 43 3.5 0.5 3.2 3 0 0 3 3 3 0 Retroviral envelope protein Polysacc_deac_1 PF01522.16 EMD68031.1 - 2.1e-21 75.8 0.0 4.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EMD68031.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.16 EMD68032.1 - 6.2e-95 318.6 0.1 8e-95 318.2 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3762 PF12591.3 EMD68032.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) adh_short PF00106.20 EMD68033.1 - 1.6e-25 89.9 0.9 2.7e-25 89.2 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD68033.1 - 7e-23 81.6 0.0 8.3e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68033.1 - 7.2e-08 32.2 0.3 7.2e-08 32.2 0.2 1.5 2 0 0 2 2 2 1 KR domain ThiF PF00899.16 EMD68033.1 - 0.72 9.6 3.8 0.93 9.3 1.2 2.1 1 1 1 2 2 2 0 ThiF family Fungal_trans PF04082.13 EMD68034.1 - 2.4e-14 52.8 0.6 3.7e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD68035.1 - 3.7e-32 111.3 37.6 3.4e-31 108.2 14.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68035.1 - 8.6e-11 41.0 20.0 2.3e-09 36.3 13.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2534 PF10749.4 EMD68035.1 - 5.5 6.9 8.8 12 5.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) SPC12 PF06645.8 EMD68035.1 - 7.4 6.4 11.7 1.2 8.9 0.1 3.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Iso_dh PF00180.15 EMD68036.1 - 3.1e-89 299.3 0.0 3.6e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RPAP3_C PF13877.1 EMD68036.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Fungal_trans PF04082.13 EMD68037.1 - 7.1e-24 84.0 1.7 1.9e-23 82.6 1.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2383 PF09537.5 EMD68037.1 - 0.16 12.2 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) E1-E2_ATPase PF00122.15 EMD68038.1 - 1.7e-38 131.9 0.3 3e-38 131.1 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMD68038.1 - 1.4e-25 90.9 0.0 2.9e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD68038.1 - 2.5e-15 57.1 0.0 6.8e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD68038.1 - 1.7e-05 24.5 4.4 4.7e-05 23.1 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMD68038.1 - 0.0005 20.1 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Acid_phosphat_B PF03767.9 EMD68038.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF3981 PF13139.1 EMD68038.1 - 0.2 11.6 1.3 4.3 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) DUF1772 PF08592.6 EMD68038.1 - 0.7 9.6 8.0 0.33 10.6 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Rad4 PF03835.10 EMD68039.1 - 9.6e-28 96.4 0.6 2.1e-27 95.2 0.4 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMD68039.1 - 1.4e-27 95.1 0.1 2.5e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMD68039.1 - 1.6e-17 62.7 0.1 3.1e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMD68039.1 - 8.2e-14 51.6 0.0 2.4e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EMD68039.1 - 0.00026 21.1 0.0 0.00099 19.2 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily E1_dh PF00676.15 EMD68040.1 - 2.1e-89 299.1 0.0 2.8e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 EMD68040.1 - 0.00036 19.4 0.1 0.00087 18.1 0.1 1.6 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 EMD68040.1 - 0.0025 17.4 1.3 0.0054 16.3 0.1 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EMD68040.1 - 0.022 13.7 0.0 0.057 12.3 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KapB PF08810.5 EMD68040.1 - 0.053 13.5 0.3 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Kinase associated protein B Ubie_methyltran PF01209.13 EMD68041.1 - 1.8e-79 266.1 0.0 2.4e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMD68041.1 - 9.4e-16 57.7 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD68041.1 - 1.9e-13 50.6 0.0 3.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD68041.1 - 5.4e-10 39.6 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD68041.1 - 6.4e-10 38.9 0.0 1.3e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD68041.1 - 2.1e-09 37.6 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD68041.1 - 4.1e-09 36.9 0.0 9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD68041.1 - 3.4e-06 27.0 0.2 1.3e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Mito_fiss_reg PF05308.6 EMD68041.1 - 0.041 13.2 1.0 0.072 12.4 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_8 PF05148.10 EMD68041.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.8 3 0 0 3 3 3 0 Hypothetical methyltransferase DREV PF05219.7 EMD68041.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CAP_N PF01213.14 EMD68041.1 - 0.29 10.3 3.5 0.44 9.7 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATG13 PF10033.4 EMD68042.1 - 1.6e-59 201.2 0.0 3.1e-59 200.2 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.13 EMD68043.1 - 1.5e-21 76.3 0.1 2.5e-07 30.8 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMD68043.1 - 3.5e-13 48.7 2.5 9.8e-10 37.7 0.1 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EMD68043.1 - 5.3e-10 39.5 0.3 6.2e-09 36.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BTB PF00651.26 EMD68043.1 - 7.4e-10 38.8 0.0 0.00085 19.2 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain Ank_3 PF13606.1 EMD68043.1 - 1.1e-07 31.4 0.4 0.035 14.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMD68043.1 - 3.1e-06 27.4 0.1 2.1e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD68043.1 - 0.0015 18.6 0.6 0.15 12.3 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD68043.1 - 0.0023 17.6 0.1 2.1 8.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Nup96 PF12110.3 EMD68044.1 - 1.3e-89 300.1 0.1 1.8e-89 299.6 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EMD68044.1 - 6.2e-41 139.5 0.0 1.1e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EMD68044.1 - 7.7e-23 80.8 432.9 1.3e-11 44.7 35.9 12.9 4 2 6 10 10 10 6 Nucleoporin FG repeat region DUF4288 PF14119.1 EMD68044.1 - 0.48 10.5 0.3 2.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) EF-hand_1 PF00036.27 EMD68045.1 - 1.3e-20 71.0 7.8 6.1e-09 34.5 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMD68045.1 - 4e-20 71.7 4.0 9.6e-11 41.6 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMD68045.1 - 1.1e-18 65.3 6.4 3.9e-08 32.5 0.2 3.8 3 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMD68045.1 - 5.3e-18 64.3 6.9 1.3e-11 43.9 0.2 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMD68045.1 - 1.4e-13 49.5 5.9 2.7e-05 23.2 0.1 3.8 3 1 1 4 4 4 3 EF hand EF-hand_4 PF12763.2 EMD68045.1 - 1.2e-06 28.2 0.0 0.0006 19.5 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMD68045.1 - 0.00054 19.8 0.1 0.43 10.5 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EMD68045.1 - 0.014 15.3 0.2 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SPX PF03105.14 EMD68045.1 - 0.076 12.7 0.2 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 SPX domain Caleosin PF05042.8 EMD68045.1 - 0.081 12.4 0.0 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Caleosin related protein MgtE_N PF03448.12 EMD68045.1 - 0.26 11.6 2.5 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 MgtE intracellular N domain Complex1_51K PF01512.12 EMD68046.1 - 2e-47 160.7 0.0 3.5e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EMD68046.1 - 7.4e-19 66.6 0.4 7.4e-19 66.6 0.3 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EMD68046.1 - 3.3e-09 36.5 0.0 7.9e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 SLBB domain CN_hydrolase PF00795.17 EMD68048.1 - 2.1e-25 89.1 0.0 3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dehydratase_MU PF02288.10 EMD68048.1 - 0.099 12.3 0.2 0.68 9.6 0.1 2.2 1 1 0 1 1 1 0 Dehydratase medium subunit FMN_dh PF01070.13 EMD68049.1 - 1.4e-88 297.1 0.0 1.3e-46 159.1 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.16 EMD68049.1 - 0.00015 21.0 0.5 0.11 11.7 0.0 3.0 1 1 2 3 3 3 2 Histidine biosynthesis protein IMPDH PF00478.20 EMD68049.1 - 0.00085 18.3 0.0 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMD68049.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 EMD68049.1 - 0.012 14.5 0.2 1.2 7.9 0.0 2.7 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase QRPTase_C PF01729.14 EMD68049.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain VWA_N PF08399.6 EMD68049.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 VWA N-terminal DUF4231 PF14015.1 EMD68050.1 - 6.7 6.7 7.0 6.7 6.7 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_M14 PF00246.19 EMD68051.1 - 1.3e-38 133.2 0.3 1.6e-38 132.9 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AMP-binding PF00501.23 EMD68052.1 - 3.8e-79 266.0 0.0 5.5e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD68052.1 - 0.00091 20.1 0.0 0.004 18.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SCPU PF05229.10 EMD68052.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain FAD_binding_4 PF01565.18 EMD68056.1 - 2.2e-21 75.7 1.5 1.9e-20 72.7 1.0 2.2 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD68056.1 - 0.0013 18.6 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Response_reg PF00072.19 EMD68057.1 - 4.1e-19 68.6 0.4 2e-18 66.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMD68057.1 - 1.3e-10 41.1 0.0 4.4e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAT1 PF09770.4 EMD68058.1 - 9.5 4.3 22.9 11 4.0 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F_actin_bind PF08919.5 EMD68060.1 - 0.0073 16.0 0.4 0.016 14.8 0.3 1.6 1 1 0 1 1 1 1 F-actin binding Laminin_II PF06009.7 EMD68060.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF1395 PF07160.7 EMD68060.1 - 0.019 14.4 0.2 0.027 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Syntaxin-6_N PF09177.6 EMD68060.1 - 0.043 14.2 0.1 0.076 13.4 0.1 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal ALIX_LYPXL_bnd PF13949.1 EMD68060.1 - 0.051 12.5 1.1 1.4 7.8 0.4 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV CagA PF03507.8 EMD68060.1 - 0.079 12.8 0.4 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 CagA exotoxin Effector_1 PF04518.7 EMD68060.1 - 0.55 9.1 2.5 0.39 9.6 0.3 1.6 1 1 1 2 2 2 0 Effector from type III secretion system NAD_synthase PF02540.12 EMD68061.1 - 8.7e-26 90.2 0.0 6.1e-25 87.5 0.0 2.0 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EMD68061.1 - 6.5e-18 64.7 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EMD68061.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Asparagine synthase Response_reg PF00072.19 EMD68062.1 - 3.5e-22 78.5 1.4 2.4e-21 75.8 0.4 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EMD68062.1 - 3.7e-22 78.1 0.0 7.9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD68062.1 - 4.6e-14 52.1 0.2 1.3e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EMD68062.1 - 7.4e-06 26.0 0.0 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 GAF domain HATPase_c_3 PF13589.1 EMD68062.1 - 0.0072 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EMD68062.1 - 0.052 13.6 0.0 0.27 11.3 0.0 2.3 1 1 0 1 1 1 0 GAF domain MetRS-N PF09635.5 EMD68062.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 MetRS-N binding domain YlaH PF14036.1 EMD68063.1 - 0.7 10.0 0.1 0.7 10.0 0.0 3.2 4 0 0 4 4 4 0 YlaH-like protein Reticulon PF02453.12 EMD68064.1 - 1.2e-40 138.8 1.2 1.8e-40 138.3 0.9 1.2 1 0 0 1 1 1 1 Reticulon DUF2515 PF10720.4 EMD68065.1 - 0.043 12.7 0.5 0.072 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) Cupin_8 PF13621.1 EMD68066.1 - 5e-37 127.7 0.0 7.5e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMD68066.1 - 7e-07 28.7 0.0 9.5e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein DUF454 PF04304.8 EMD68067.1 - 2.6 8.1 6.9 0.55 10.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF454) TFIIE_beta PF02186.10 EMD68068.1 - 4.1e-06 26.6 0.1 6.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 TFIIE beta subunit core domain CFEM PF05730.6 EMD68069.1 - 1.6e-11 43.8 16.0 3.3e-11 42.8 11.1 1.6 1 0 0 1 1 1 1 CFEM domain DUF998 PF06197.8 EMD68069.1 - 0.0048 16.2 5.8 0.0048 16.2 4.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF998) Caveolin PF01146.12 EMD68069.1 - 0.29 10.7 7.0 0.085 12.4 1.0 2.4 1 1 1 2 2 2 0 Caveolin TIL PF01826.12 EMD68069.1 - 2 8.5 10.3 4.6 7.4 7.1 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain adh_short PF00106.20 EMD68070.1 - 1.4e-24 86.9 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD68070.1 - 4.6e-11 42.9 0.0 5.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68070.1 - 4.1e-07 29.8 0.0 8e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD68070.1 - 7.1e-07 28.8 0.0 2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD68070.1 - 3e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD68070.1 - 0.00016 20.7 0.1 0.00022 20.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMD68070.1 - 0.00032 21.0 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMD68070.1 - 0.00037 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 EMD68070.1 - 0.00081 18.6 0.1 0.00094 18.3 0.1 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 EMD68070.1 - 0.02 14.8 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 EMD68070.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EMD68070.1 - 0.027 13.3 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EMD68070.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMD68070.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMD68070.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4321 PF14209.1 EMD68070.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) SH3_1 PF00018.23 EMD68071.1 - 1.5e-13 49.8 0.1 2.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMD68071.1 - 5.2e-10 38.7 0.0 7.8e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMD68071.1 - 8.9e-10 37.9 0.0 1.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CDC27 PF09507.5 EMD68071.1 - 6.3 5.8 6.2 15 4.6 4.3 1.7 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Tyrosinase PF00264.15 EMD68072.1 - 1.6e-48 165.8 1.0 1.7e-48 165.6 0.1 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase zf-DHHC PF01529.15 EMD68073.1 - 6.6 6.0 6.4 1.3e+02 1.8 4.5 2.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase MANEC PF07502.9 EMD68075.1 - 6.8 6.7 9.1 1.9 8.5 0.5 2.1 1 1 1 2 2 2 0 MANEC domain Glyco_tran_28_C PF04101.11 EMD68078.1 - 1.5e-18 66.9 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EMD68078.1 - 8.2e-06 25.2 0.0 9.7e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 EMD68078.1 - 0.14 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.4 EMD68079.1 - 2.1e-42 144.2 0.0 3.5e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ino80_Iec3 PF14612.1 EMD68080.1 - 1.4e-76 257.5 2.0 1.4e-76 257.5 1.4 1.5 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling SHOCT PF09851.4 EMD68080.1 - 0.039 13.4 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain CDC45 PF02724.9 EMD68080.1 - 4.1 5.3 10.1 0.067 11.2 1.0 1.9 2 0 0 2 2 2 0 CDC45-like protein ORMDL PF04061.9 EMD68081.1 - 3.8e-58 194.8 1.7 4.4e-58 194.6 1.2 1.0 1 0 0 1 1 1 1 ORMDL family Na_H_Exchanger PF00999.16 EMD68082.1 - 6.2e-51 173.1 29.5 8.1e-51 172.7 20.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_M20 PF01546.23 EMD68083.1 - 1.3e-27 96.5 0.3 4.1e-27 94.9 0.2 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD68083.1 - 3.3e-11 42.9 0.0 8.5e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMD68083.1 - 8.3e-05 22.3 0.0 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 1 Peptidase family M28 DNase_NucA_NucB PF14040.1 EMD68085.1 - 0.0094 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Glyco_hydro_18 PF00704.23 EMD68086.1 - 1.8e-42 146.0 0.7 6.4e-37 127.7 0.1 2.1 1 1 0 2 2 2 2 Glycosyl hydrolases family 18 DUF4428 PF14471.1 EMD68087.1 - 0.064 13.0 0.4 0.28 10.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) RGS PF00615.14 EMD68088.1 - 0.00016 21.7 0.2 0.00099 19.2 0.2 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain UNC-93 PF05978.11 EMD68088.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 ATP_bind_3 PF01171.15 EMD68089.1 - 1.9e-18 66.5 0.0 3.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EMD68089.1 - 0.0018 18.6 0.0 0.0042 17.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EMD68089.1 - 0.0042 16.4 1.3 0.0042 16.4 0.9 3.6 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 EMD68089.1 - 0.0089 14.6 0.0 0.016 13.8 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase zf-UBR PF02207.15 EMD68089.1 - 5 6.9 9.1 2.3 7.9 1.2 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.21 EMD68090.1 - 4.4e-164 546.4 11.7 6.8e-164 545.8 8.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMD68090.1 - 1.6e-09 37.4 0.9 1.6e-09 37.4 0.6 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like YjgF_endoribonc PF14588.1 EMD68090.1 - 0.21 11.5 0.1 9.4 6.1 0.0 2.7 3 0 0 3 3 3 0 YjgF/chorismate_mutase-like, putative endoribonuclease Dynamin_N PF00350.18 EMD68091.1 - 5.9e-14 52.2 0.0 5.2e-12 45.9 0.0 3.1 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 EMD68091.1 - 0.0024 17.8 0.4 0.035 14.0 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 EMD68091.1 - 0.0035 17.8 0.1 1 9.8 0.0 3.8 4 0 0 4 4 4 1 Miro-like protein MMR_HSR1 PF01926.18 EMD68091.1 - 0.0039 17.1 0.0 1.8 8.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMD68091.1 - 0.0075 15.3 1.2 0.029 13.4 0.1 2.3 2 0 0 2 2 2 1 AIG1 family T2SE PF00437.15 EMD68091.1 - 0.017 14.0 0.0 0.045 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.8 EMD68091.1 - 0.02 13.7 0.1 0.02 13.7 0.0 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EMD68091.1 - 0.041 14.1 4.0 0.099 12.9 0.0 3.3 4 0 0 4 4 4 0 ABC transporter AAA_29 PF13555.1 EMD68091.1 - 0.079 12.5 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EMD68091.1 - 0.11 12.3 2.0 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EMD68091.1 - 0.15 11.4 1.8 0.53 9.6 0.0 2.5 2 2 1 3 3 3 0 AAA-like domain Ded_cyto PF06920.8 EMD68091.1 - 0.18 11.1 3.9 4.8 6.4 0.2 3.6 2 1 1 3 3 3 0 Dedicator of cytokinesis HECT PF00632.20 EMD68092.1 - 4.6e-86 288.8 0.0 7.8e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans_2 PF11951.3 EMD68092.1 - 2.9e-12 45.8 5.0 5.6e-12 44.9 1.3 2.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68092.1 - 2.1e-07 30.7 11.2 4.3e-07 29.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IQ PF00612.22 EMD68092.1 - 0.001 18.5 1.7 0.0039 16.6 1.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif ENTH PF01417.15 EMD68094.1 - 3.4e-47 159.3 0.1 5.1e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMD68094.1 - 0.0013 17.5 0.0 0.0021 16.7 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EMD68094.1 - 0.0021 17.4 0.0 0.0046 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 EMD68094.1 - 0.12 12.0 8.0 2 8.2 0.4 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-C2H2 PF00096.21 EMD68095.1 - 1.6e-22 78.4 24.6 2.6e-05 24.2 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD68095.1 - 4.6e-22 77.1 23.2 3.1e-07 30.3 0.7 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD68095.1 - 9.5e-16 56.8 23.7 0.00028 21.0 2.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD68095.1 - 1.7e-05 24.7 9.1 0.83 9.8 0.0 5.3 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMD68095.1 - 0.015 15.2 17.0 1.4 8.8 0.8 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EMD68095.1 - 0.053 13.7 15.1 1.8 8.8 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.13 EMD68095.1 - 0.089 12.4 0.3 0.089 12.4 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EMD68095.1 - 0.11 12.4 11.0 6.5 6.7 1.1 3.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 EMD68095.1 - 0.12 12.0 7.4 5.9 6.6 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.7 EMD68095.1 - 0.27 11.2 1.6 5.2 7.1 0.0 2.7 2 1 1 3 3 3 0 TFIIH C1-like domain C1_1 PF00130.17 EMD68095.1 - 2 8.1 6.6 1.1 9.0 1.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 EMD68095.1 - 9.3 5.8 8.5 40 3.8 2.0 3.3 2 1 0 2 2 2 0 zinc-ribbon domain Peptidase_M17_N PF02789.12 EMD68096.1 - 0.092 12.4 0.0 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain NAD_binding_1 PF00175.16 EMD68097.1 - 2.5e-12 47.2 0.0 4.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMD68097.1 - 5.4e-10 39.5 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 EMD68097.1 - 9.4e-07 28.8 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMD68097.1 - 0.0001 22.2 0.0 0.051 13.4 0.0 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Protoglobin PF11563.3 EMD68097.1 - 0.00028 20.5 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Protoglobin DUF4014 PF13198.1 EMD68098.1 - 4 7.9 6.6 4.6 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4014) Inositol_P PF00459.20 EMD68099.1 - 5.6e-54 183.2 1.0 1.1e-53 182.3 0.7 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 EMD68100.1 - 1.4e-40 138.1 0.1 4.5e-32 110.6 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EMD68100.1 - 1.1e-23 82.8 1.0 1.8e-22 78.9 0.2 2.6 2 0 0 2 2 2 1 Rsm1-like Fungal_trans PF04082.13 EMD68102.1 - 0.0023 16.8 0.9 0.006 15.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EMD68103.1 - 2.7e-09 36.6 1.8 3.9e-09 36.1 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMD68103.1 - 1.5e-07 31.4 0.2 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMD68103.1 - 0.00053 19.7 0.4 0.00078 19.2 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMD68103.1 - 0.0033 17.4 1.5 0.0054 16.7 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD68103.1 - 0.015 14.9 0.9 0.025 14.2 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EMD68103.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 zinc-finger zf-C3HC4_3 PF13920.1 EMD68103.1 - 0.13 11.9 0.4 0.3 10.8 0.3 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 EMD68105.1 - 4.2e-25 88.2 59.3 1.8e-15 56.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD68105.1 - 0.0064 16.2 0.4 0.043 13.5 0.0 2.6 2 1 0 2 2 2 1 MFS_1 like family WD40 PF00400.27 EMD68107.1 - 1.3e-40 135.7 13.8 1.1e-06 28.2 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EMD68107.1 - 6e-11 41.9 1.8 1.2e-10 40.9 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD68107.1 - 6.6e-07 28.8 0.6 1.3e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMD68107.1 - 2.5e-06 25.9 0.1 0.31 9.1 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMD68107.1 - 0.005 16.5 0.0 42 3.9 0.0 3.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EMD68107.1 - 0.011 15.2 0.1 0.087 12.2 0.0 2.3 1 1 0 2 2 2 0 PQQ-like domain PH_10 PF15411.1 EMD68108.1 - 7.2e-43 145.4 0.4 1.7e-42 144.2 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EMD68108.1 - 6.7e-32 109.4 0.1 2.8e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 EMD68108.1 - 1.2e-31 109.9 0.1 2.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EMD68108.1 - 2.8e-10 39.6 0.0 6.9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EMD68108.1 - 0.029 14.5 0.2 0.069 13.3 0.1 1.5 1 0 0 1 1 1 0 PH domain Imm40 PF15582.1 EMD68108.1 - 0.08 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 40 DND1_DSRM PF14709.1 EMD68109.1 - 0.15 12.3 1.5 0.45 10.8 0.4 2.2 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Dabb PF07876.7 EMD68110.1 - 0.0018 18.6 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain NDT80_PhoG PF05224.7 EMD68111.1 - 0.21 11.5 1.9 0.33 10.9 1.3 1.3 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family PAT1 PF09770.4 EMD68111.1 - 2 6.5 7.2 2.2 6.4 5.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NTP_transferase PF00483.18 EMD68112.1 - 6.4e-48 163.2 0.0 1.5e-47 162.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase 2_5_RNA_ligase2 PF13563.1 EMD68112.1 - 7.6e-15 54.9 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Hexapep PF00132.19 EMD68112.1 - 9.4e-14 50.2 6.9 5.9e-10 38.2 0.8 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMD68112.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EMD68112.1 - 8e-08 31.7 6.6 9.9e-07 28.2 0.8 2.9 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EMD68112.1 - 0.0057 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 EMD68112.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YjbR PF04237.8 EMD68112.1 - 0.12 12.7 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 YjbR ubiquitin PF00240.18 EMD68114.1 - 1.1e-137 447.5 19.0 7.1e-34 115.0 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EMD68114.1 - 4e-79 260.3 20.6 2.9e-19 68.4 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMD68114.1 - 3.1e-24 85.0 7.6 0.00028 21.0 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMD68114.1 - 2.7e-19 69.4 0.3 0.0043 16.7 0.0 4.1 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMD68114.1 - 6.7e-14 51.7 3.0 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD68114.1 - 7.6e-14 51.6 1.5 0.15 12.2 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMD68114.1 - 1.6e-09 37.6 0.0 3 7.9 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EMD68114.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EMD68114.1 - 8.4e-07 28.3 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EMD68114.1 - 8.1e-06 25.6 4.5 8.5 6.3 0.0 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EMD68114.1 - 0.00082 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 EMD68114.1 - 0.0016 17.9 0.1 55 3.1 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EMD68114.1 - 0.0058 15.0 14.6 7.3 4.7 0.2 6.5 5 3 0 5 5 5 0 Plexin cytoplasmic RasGAP domain GABP-alpha PF11620.3 EMD68114.1 - 0.007 16.3 6.2 37 4.3 0.0 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain CTDII PF01556.13 EMD68114.1 - 0.0099 15.7 13.8 6.9 6.6 0.2 4.5 1 1 3 4 4 4 1 DnaJ C terminal domain DUF3861 PF12977.2 EMD68114.1 - 0.013 15.5 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 EMD68114.1 - 0.028 14.3 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif CDC48_2 PF02933.12 EMD68114.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 FERM_N PF09379.5 EMD68114.1 - 1.6 8.8 11.8 90 3.2 0.1 5.6 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EMD68114.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) DUF3244 PF11589.3 EMD68114.1 - 6.9 6.4 7.8 1.6e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3244) Aldo_ket_red PF00248.16 EMD68115.1 - 2.2e-67 226.8 0.2 2.4e-67 226.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3647 PF12363.3 EMD68115.1 - 0.14 12.2 1.0 1.6 8.8 0.0 2.8 4 0 0 4 4 4 0 Phage protein RHH_1 PF01402.16 EMD68115.1 - 0.24 11.3 1.1 2 8.4 0.0 3.1 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family HWE_HK PF07536.9 EMD68116.1 - 0.13 12.6 0.9 0.17 12.3 0.7 1.2 1 0 0 1 1 1 0 HWE histidine kinase Zn_clus PF00172.13 EMD68117.1 - 0.0042 16.9 7.8 0.0099 15.7 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 EMD68117.1 - 0.093 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Cupin_2 PF07883.6 EMD68118.1 - 6.7e-07 28.7 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Prenyltrans PF00432.16 EMD68119.1 - 6.4e-37 124.7 26.9 1e-08 34.5 2.5 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMD68119.1 - 3.7e-22 78.8 1.5 3.2e-12 46.8 0.0 3.6 1 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMD68119.1 - 0.0004 20.3 0.1 0.022 14.7 0.0 3.0 3 0 0 3 3 3 1 Prenyltransferase-like ARID PF01388.16 EMD68120.1 - 8.2e-20 70.4 0.0 1.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Diphthamide_syn PF01866.12 EMD68122.1 - 5.9e-55 186.6 0.0 9.3e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PAXIP1_C PF15364.1 EMD68122.1 - 0.86 9.5 6.5 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein PLA2_B PF01735.13 EMD68123.1 - 3.9e-179 595.9 0.9 4.6e-179 595.6 0.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain COesterase PF00135.23 EMD68124.1 - 4.7e-78 263.2 0.4 1.3e-77 261.7 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD68124.1 - 8.5e-09 35.2 0.0 2.1e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DIOX_N PF14226.1 EMD68125.1 - 6.7e-27 94.3 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMD68125.1 - 4.4e-17 62.2 0.0 8.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NTP_transferase PF00483.18 EMD68126.1 - 4.7e-30 104.6 0.0 6.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EMD68126.1 - 1.2e-13 49.8 7.4 1.8e-08 33.4 0.4 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMD68126.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EMD68126.1 - 0.0079 15.7 1.6 0.069 12.7 0.1 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EMD68126.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase zf-RING_4 PF14570.1 EMD68128.1 - 6.4e-20 70.4 12.5 1.2e-19 69.6 8.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EMD68128.1 - 2.5e-09 36.6 0.0 6.6e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EMD68128.1 - 2.3e-05 23.9 10.0 4.2e-05 23.1 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EMD68128.1 - 8.5e-05 22.3 0.1 0.00018 21.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EMD68128.1 - 0.00071 18.1 38.3 0.00071 18.1 26.6 2.5 1 1 1 2 2 1 1 Microtubule-binding protein MIP-T3 RRM_6 PF14259.1 EMD68128.1 - 0.00084 19.2 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 EMD68128.1 - 0.0036 17.1 6.0 0.0093 15.8 4.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger Rtf2 PF04641.7 EMD68128.1 - 0.0036 16.5 3.1 0.0036 16.5 2.2 3.4 4 0 0 4 4 4 1 Rtf2 RING-finger SET_assoc PF11767.3 EMD68128.1 - 0.0047 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Baculo_IE-1 PF05290.6 EMD68128.1 - 0.0055 16.4 6.1 0.011 15.4 4.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Pox_Ag35 PF03286.9 EMD68128.1 - 0.0058 16.1 20.0 0.0058 16.1 13.9 2.9 3 0 0 3 3 3 1 Pox virus Ag35 surface protein zf-C3HC4 PF00097.20 EMD68128.1 - 0.14 11.8 10.2 0.3 10.7 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ycf1 PF05758.7 EMD68128.1 - 0.86 7.2 18.1 0.054 11.2 8.6 1.7 2 0 0 2 2 2 0 Ycf1 Complex1_30kDa PF00329.14 EMD68129.1 - 1.8e-35 121.2 0.0 2.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1349 PF07081.6 EMD68130.1 - 4.9e-11 42.3 0.0 7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF3361 PF11841.3 EMD68131.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) DCX PF03607.12 EMD68131.1 - 0.091 12.3 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Doublecortin FdhE PF04216.7 EMD68131.1 - 0.13 11.9 0.3 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4419 PF14388.1 EMD68131.1 - 1 8.5 2.8 0.31 10.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) TRAM_LAG1_CLN8 PF03798.11 EMD68133.1 - 2.3e-49 167.6 13.9 2.3e-49 167.6 9.6 1.4 2 0 0 2 2 2 1 TLC domain Cutinase PF01083.17 EMD68134.1 - 1e-22 80.7 0.1 1e-22 80.7 0.0 2.3 2 1 0 2 2 2 1 Cutinase tRNA-synt_2b PF00587.20 EMD68136.1 - 1.4e-25 89.8 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMD68136.1 - 6.1e-14 51.9 2.8 6.1e-14 51.9 1.9 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Peptidase_S46 PF10459.4 EMD68136.1 - 0.026 12.9 1.8 0.037 12.4 1.2 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3584 PF12128.3 EMD68136.1 - 0.034 11.4 2.7 0.046 11.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.1 EMD68136.1 - 0.043 13.2 3.6 0.076 12.4 2.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.10 EMD68136.1 - 0.068 12.6 7.9 0.49 9.9 0.2 2.6 3 0 0 3 3 3 0 Septum formation initiator AAA_13 PF13166.1 EMD68136.1 - 0.083 11.3 1.3 0.12 10.8 0.9 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EMD68136.1 - 1.5 9.2 3.7 12 6.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) BTB PF00651.26 EMD68137.1 - 0.13 12.2 0.0 0.85 9.6 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain WSK PF03832.8 EMD68138.1 - 0.15 11.4 5.0 29 4.1 0.0 4.0 5 0 0 5 5 5 0 WSK motif Hydrophobin_2 PF06766.6 EMD68140.1 - 1.6e-09 37.3 9.9 2.9e-09 36.4 6.8 1.4 1 1 0 1 1 1 1 Fungal hydrophobin UQ_con PF00179.21 EMD68141.1 - 1.8e-43 147.3 0.0 2e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD68141.1 - 0.012 15.3 0.1 0.027 14.2 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B CTP_transf_1 PF01148.15 EMD68142.1 - 4.9e-17 62.4 6.5 2.7e-15 56.7 1.0 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family DEAD PF00270.24 EMD68143.1 - 6.9e-36 123.2 0.0 5.2e-35 120.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMD68143.1 - 3.2e-18 65.0 0.0 6.3e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMD68143.1 - 5.9e-18 64.5 0.0 1.7e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD68143.1 - 0.0083 15.9 2.3 0.074 12.8 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SSFA2_C PF14723.1 EMD68143.1 - 0.14 11.9 4.2 0.26 10.9 2.9 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus SLAC1 PF03595.12 EMD68145.1 - 1.8e-85 286.5 50.2 2e-85 286.3 34.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Se-cys_synth_N PF12390.3 EMD68149.1 - 0.033 14.2 0.2 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal DDE_1 PF03184.14 EMD68150.1 - 1.7e-13 50.2 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMD68151.1 - 1.5e-11 43.9 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD68151.1 - 4.1e-06 26.2 0.2 7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD68151.1 - 0.0031 17.6 1.0 0.0042 17.2 0.4 1.5 1 1 1 2 2 2 1 Winged helix-turn helix Drf_GBD PF06371.8 EMD68151.1 - 0.025 13.9 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_28 PF13518.1 EMD68151.1 - 0.047 13.6 0.1 0.29 11.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD68151.1 - 0.066 12.8 0.3 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Aldose_epim PF01263.15 EMD68152.1 - 1.6e-50 171.9 0.1 1.9e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AIRC PF00731.15 EMD68153.1 - 0.1 11.8 0.4 0.23 10.7 0.3 1.5 1 0 0 1 1 1 0 AIR carboxylase Amidohydro_5 PF13594.1 EMD68154.1 - 3.4e-07 29.9 0.0 7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMD68154.1 - 7.7e-05 22.8 0.0 0.00013 22.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase DUF4447 PF14590.1 EMD68154.1 - 0.0059 16.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4447) SWIB PF02201.13 EMD68155.1 - 4.7e-12 45.4 0.0 9.4e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 EMD68156.1 - 9.8e-60 201.8 0.0 1.3e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD68156.1 - 1e-31 109.9 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD68156.1 - 5.8e-06 25.4 0.0 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMD68156.1 - 0.0017 17.4 0.2 0.0036 16.3 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD68156.1 - 0.012 15.4 2.4 0.017 14.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF747 PF05346.6 EMD68157.1 - 9.2e-131 435.8 7.4 1.2e-130 435.4 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family ABC2_membrane PF01061.19 EMD68158.1 - 2.5e-96 320.8 60.2 3e-50 170.3 17.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EMD68158.1 - 2.7e-38 129.7 4.8 3.8e-32 110.0 0.2 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EMD68158.1 - 5.4e-37 127.1 0.0 5.4e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EMD68158.1 - 1.4e-19 69.9 0.0 3.2e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMD68158.1 - 3.2e-07 29.9 0.1 0.00031 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMD68158.1 - 4.6e-06 26.5 0.1 0.015 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EMD68158.1 - 4.9e-06 25.8 42.9 0.00089 18.3 10.6 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 EMD68158.1 - 7.2e-05 22.1 0.0 0.14 11.3 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMD68158.1 - 0.00011 21.4 0.0 0.0084 15.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMD68158.1 - 0.00023 20.6 2.0 0.014 14.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMD68158.1 - 0.0005 20.0 6.9 0.00081 19.4 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_21 PF13304.1 EMD68158.1 - 0.00069 19.6 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EMD68158.1 - 0.0016 17.8 0.3 0.072 12.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EMD68158.1 - 0.0033 17.5 0.4 1.1 9.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain Hum_adeno_E3A PF05393.6 EMD68158.1 - 0.036 13.7 2.0 0.81 9.3 0.2 2.6 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein AAA_18 PF13238.1 EMD68158.1 - 0.055 13.7 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMD68158.1 - 0.073 13.3 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMD68158.1 - 0.13 11.6 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.7 EMD68158.1 - 0.15 11.7 2.1 4.7 6.8 0.4 2.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EMD68158.1 - 0.18 11.5 2.5 15 5.3 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain Phtf-FEM1B_bdg PF12129.3 EMD68158.1 - 0.27 10.5 2.5 0.71 9.2 0.0 2.7 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor UPF0079 PF02367.12 EMD68158.1 - 0.28 10.8 1.1 5.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2615 PF11027.3 EMD68158.1 - 0.39 10.6 2.8 6.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) AAA_10 PF12846.2 EMD68158.1 - 0.8 9.0 3.8 9.7 5.5 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain p450 PF00067.17 EMD68161.1 - 1.8e-44 152.0 0.0 2.3e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMD68162.1 - 6e-20 71.2 41.0 6e-20 71.2 28.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EMD68163.1 - 1.3e-24 85.8 6.6 2.2e-24 85.1 4.6 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Methyltransf_6 PF03737.10 EMD68163.1 - 8.2e-20 71.2 0.6 1.2e-19 70.7 0.4 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase ApbA PF02558.11 EMD68163.1 - 0.011 15.1 0.1 0.026 13.9 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CobT PF06213.7 EMD68163.1 - 0.054 12.6 9.2 0.077 12.1 6.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EMD68163.1 - 1.2 7.0 13.2 1.4 6.7 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMD68163.1 - 6.1 5.2 20.2 7.9 4.8 14.0 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_M41 PF01434.13 EMD68164.1 - 9.2e-66 221.3 0.4 1.4e-65 220.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMD68164.1 - 5.8e-43 146.2 0.0 1.3e-42 145.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD68164.1 - 6.6e-06 25.8 0.0 3.6e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD68164.1 - 3.6e-05 23.8 1.2 0.00028 20.9 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMD68164.1 - 3.7e-05 23.2 0.8 0.017 14.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 EMD68164.1 - 4.5e-05 22.3 0.0 8.6e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EMD68164.1 - 0.00032 21.4 0.0 0.0011 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMD68164.1 - 0.00075 19.6 0.3 0.075 13.1 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD68164.1 - 0.002 18.0 0.1 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD68164.1 - 0.0026 17.4 0.3 0.0095 15.6 0.2 1.9 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EMD68164.1 - 0.0045 16.0 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMD68164.1 - 0.0056 16.1 0.1 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMD68164.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EMD68164.1 - 0.031 13.4 0.1 0.065 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMD68164.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMD68164.1 - 0.049 12.7 0.0 0.96 8.5 0.0 2.3 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EMD68164.1 - 0.1 11.8 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_2 PF07724.9 EMD68164.1 - 0.11 12.4 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EMD68164.1 - 0.14 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 EMD68165.1 - 4.1e-05 23.2 5.1 4.1e-05 23.2 3.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EMD68165.1 - 0.0011 18.9 8.3 0.0011 18.9 5.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor G-alpha PF00503.15 EMD68166.1 - 5e-48 163.7 0.9 8.9e-48 162.9 0.6 1.3 1 0 0 1 1 1 1 G-protein alpha subunit TAFH PF07531.9 EMD68166.1 - 0.096 12.3 0.5 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 NHR1 homology to TAF Syntaxin PF00804.20 EMD68166.1 - 1.1 9.4 6.0 4.6 7.4 0.8 3.4 3 1 0 3 3 3 0 Syntaxin F-box-like PF12937.2 EMD68167.1 - 1.1e-07 31.4 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD68167.1 - 0.0016 18.0 0.1 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EMD68167.1 - 0.011 15.5 0.0 0.27 11.2 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat adh_short_C2 PF13561.1 EMD68169.1 - 1.6e-24 87.0 0.0 1.9e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD68169.1 - 4.2e-24 85.3 3.6 7.1e-24 84.6 2.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68169.1 - 3e-14 53.0 1.9 4.1e-14 52.6 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD68169.1 - 0.0038 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF805 PF05656.9 EMD68169.1 - 0.071 12.9 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ELFV_dehydrog PF00208.16 EMD68169.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Metaviral_G PF09595.5 EMD68170.1 - 0.033 13.8 6.1 0.05 13.2 4.2 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein Peptidase_S49_N PF08496.5 EMD68170.1 - 0.67 9.7 3.0 0.31 10.8 0.7 1.4 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Uso1_p115_head PF04869.9 EMD68171.1 - 6.3e-104 347.0 0.0 1.8e-103 345.6 0.0 1.8 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Adaptin_N PF01602.15 EMD68171.1 - 0.074 11.3 0.2 1.9 6.6 0.1 2.8 2 1 1 3 3 3 0 Adaptin N terminal region FlxA PF14282.1 EMD68171.1 - 0.15 11.9 4.3 0.33 10.9 3.0 1.6 1 0 0 1 1 1 0 FlxA-like protein Nol1_Nop2_Fmu PF01189.12 EMD68172.1 - 1.1e-29 103.7 0.0 6e-20 71.7 0.0 4.1 3 1 1 4 4 4 4 NOL1/NOP2/sun family B2-adapt-app_C PF09066.5 EMD68172.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Ribosomal_L30_N PF08079.7 EMD68173.1 - 5.8e-20 71.0 17.4 1.1e-19 70.1 12.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMD68173.1 - 7.8e-20 70.2 3.3 9.4e-20 69.9 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e ADIP PF11559.3 EMD68173.1 - 1.2 9.0 10.9 2 8.3 7.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 EMD68174.1 - 9e-28 96.8 0.0 5.2e-27 94.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68174.1 - 1.5e-08 34.4 11.3 2.3e-08 33.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMD68175.1 - 3.5e-37 127.9 25.4 5.5e-30 104.2 0.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68175.1 - 1.6e-12 46.7 2.6 2.1e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD68175.1 - 1.3e-05 23.8 20.6 2.2e-05 23.0 3.4 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EMD68175.1 - 0.0018 18.0 0.2 0.088 12.6 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family RFXA_RFXANK_bdg PF15289.1 EMD68176.1 - 0.037 14.2 0.4 0.06 13.5 0.3 1.3 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain UQ_con PF00179.21 EMD68177.1 - 1.1e-08 34.6 0.1 1.8e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMD68177.1 - 0.043 13.7 0.1 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain RNase_H2-Ydr279 PF09468.5 EMD68179.1 - 0.00038 19.7 13.1 0.0004 19.6 9.1 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 EMD68179.1 - 0.0044 17.0 9.9 0.0044 17.0 6.9 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family RR_TM4-6 PF06459.7 EMD68179.1 - 0.01 15.7 5.9 0.011 15.6 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.1 EMD68179.1 - 0.022 14.3 3.8 0.023 14.2 2.6 1.1 1 0 0 1 1 1 0 AAA domain MCM_bind PF09739.4 EMD68179.1 - 0.03 13.8 1.5 0.04 13.4 1.0 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cnd1_N PF12922.2 EMD68179.1 - 0.036 13.6 5.6 0.041 13.5 3.9 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Pox_Ag35 PF03286.9 EMD68179.1 - 0.041 13.4 15.9 0.05 13.1 11.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein US2 PF02476.10 EMD68179.1 - 0.072 13.5 1.7 0.1 13.1 1.1 1.3 1 0 0 1 1 1 0 US2 family LicD PF04991.8 EMD68179.1 - 0.085 12.9 8.3 0.088 12.9 5.7 1.1 1 0 0 1 1 1 0 LicD family Serinc PF03348.10 EMD68179.1 - 0.15 10.7 0.4 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.1 EMD68179.1 - 0.32 10.6 2.9 0.49 10.0 2.0 1.3 1 0 0 1 1 1 0 FAM176 family SRP-alpha_N PF04086.8 EMD68179.1 - 0.35 10.2 17.0 0.37 10.1 11.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Eapp_C PF10238.4 EMD68179.1 - 0.46 10.3 8.5 0.66 9.8 5.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF694 PF05107.7 EMD68179.1 - 0.7 9.0 10.3 0.82 8.8 7.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) Folate_carrier PF01770.13 EMD68179.1 - 1.1 7.6 6.6 1.4 7.3 4.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier YMF19 PF02326.10 EMD68179.1 - 2.2 8.8 6.5 4.5 7.8 4.5 1.5 1 0 0 1 1 1 0 Plant ATP synthase F0 Peroxin-13_N PF04088.8 EMD68179.1 - 2.8 7.8 6.2 3.7 7.5 4.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PEX11 PF05648.9 EMD68179.1 - 3.9 6.6 8.1 4.5 6.4 5.6 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4337 PF14235.1 EMD68179.1 - 5 6.9 8.8 6.4 6.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OATP PF03137.15 EMD68179.1 - 5.6 4.9 7.1 6.4 4.6 4.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3807 PF12720.2 EMD68179.1 - 6.1 6.9 15.7 8.4 6.5 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SR-25 PF10500.4 EMD68179.1 - 8 5.8 35.8 9.8 5.5 24.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short PF00106.20 EMD68181.1 - 1.8e-26 93.0 0.2 2.8e-26 92.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD68181.1 - 9.6e-12 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68181.1 - 1.5e-07 31.2 0.4 3.4e-07 30.0 0.3 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMD68181.1 - 0.00032 19.4 0.0 0.00051 18.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD68181.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD68181.1 - 0.0018 17.4 0.0 0.0041 16.2 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Myco_arth_vir_N PF09610.5 EMD68181.1 - 0.02 14.8 0.3 0.057 13.3 0.2 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) NAD_binding_10 PF13460.1 EMD68181.1 - 0.037 14.0 0.1 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding GTP1_OBG PF01018.17 EMD68182.1 - 4.5e-38 130.3 4.8 1.4e-27 96.3 1.9 2.4 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 EMD68182.1 - 6.6e-21 74.4 0.0 1.1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMD68182.1 - 2.2e-07 30.2 0.3 5.1e-07 29.0 0.0 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 EMD68182.1 - 0.0043 17.3 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EMD68182.1 - 0.0092 15.2 0.0 0.067 12.4 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD68182.1 - 0.01 15.2 0.0 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMD68182.1 - 0.033 12.9 0.0 0.71 8.6 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EMD68182.1 - 0.064 13.0 0.1 7.2 6.4 0.1 2.3 1 1 0 2 2 2 0 Dynamin family Miro PF08477.8 EMD68182.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SUZ-C PF12901.2 EMD68183.1 - 0.004 16.7 0.6 0.018 14.6 0.6 2.0 2 0 0 2 2 2 1 SUZ-C motif Epimerase PF01370.16 EMD68184.1 - 7.9e-25 87.6 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD68184.1 - 9.8e-15 53.9 0.0 1.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD68184.1 - 1.4e-09 38.2 0.0 3.5e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD68184.1 - 1.5e-08 33.8 0.0 4.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMD68184.1 - 2.5e-08 33.1 0.0 1.1e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMD68184.1 - 1e-06 28.7 0.0 6.1e-05 22.9 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 EMD68184.1 - 1.1e-05 25.2 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 EMD68184.1 - 0.0011 18.6 0.0 0.011 15.4 0.0 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMD68184.1 - 0.013 14.4 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MMR_HSR1 PF01926.18 EMD68185.1 - 9.4e-18 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMD68185.1 - 8.8e-06 25.6 0.0 0.013 15.2 0.1 2.4 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.13 EMD68185.1 - 0.00028 20.2 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMD68185.1 - 0.0041 16.3 0.2 0.011 14.9 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMD68185.1 - 0.012 15.0 0.0 0.065 12.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EMD68185.1 - 0.013 15.2 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EMD68185.1 - 0.046 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EMD68185.1 - 0.076 12.0 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Septin Miro PF08477.8 EMD68185.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Complex1_LYR_2 PF13233.1 EMD68186.1 - 1.1e-21 77.2 0.4 1.2e-21 77.0 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EMD68186.1 - 0.011 15.9 1.5 0.018 15.2 1.0 1.6 1 1 0 1 1 1 0 Complex1_LYR-like HLH PF00010.21 EMD68186.1 - 0.059 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Complex1_LYR PF05347.10 EMD68186.1 - 0.075 12.8 1.1 0.14 12.0 0.8 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) SRP40_C PF05022.7 EMD68187.1 - 9.3e-23 80.5 1.5 9.3e-23 80.5 1.0 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain Sec3_C PF09763.4 EMD68188.1 - 2.2e-210 700.4 0.8 2.9e-210 700.0 0.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EMD68188.1 - 8.7e-28 96.0 0.1 1.6e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EMD68188.1 - 0.0006 18.4 0.3 0.0011 17.5 0.2 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 EMD68188.1 - 0.0085 16.1 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Sec3 exocyst complex subunit DUF1295 PF06966.7 EMD68189.1 - 3.6e-41 141.0 0.5 2.1e-39 135.2 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EMD68189.1 - 0.00079 19.4 0.6 0.0034 17.4 0.0 2.4 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 EMD68189.1 - 0.0015 18.6 0.0 0.0045 17.1 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EMD68189.1 - 0.0041 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.12 EMD68189.1 - 0.076 11.5 0.0 0.14 10.6 0.0 1.4 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.11 EMD68190.1 - 1.6e-35 122.4 32.2 2.5e-35 121.8 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Aha1_N PF09229.6 EMD68192.1 - 4.9e-36 123.5 1.3 7.2e-36 123.0 0.9 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EMD68192.1 - 1.8e-17 63.5 1.8 2.7e-17 63.0 0.4 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EMD68192.1 - 0.0051 16.9 1.2 0.0059 16.7 0.3 1.4 2 0 0 2 2 2 1 Poxvirus A12 protein DUF3166 PF11365.3 EMD68192.1 - 0.055 13.9 0.1 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) MFS_1 PF07690.11 EMD68193.1 - 5.8e-29 100.9 28.8 5.8e-29 100.9 19.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68193.1 - 1.8e-10 40.0 20.5 3.9e-10 38.8 14.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Aminotran_1_2 PF00155.16 EMD68195.1 - 1.5e-36 126.1 0.0 1.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMD68195.1 - 0.033 13.3 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase V_ATPase_I PF01496.14 EMD68196.1 - 1.3e-289 962.3 0.0 1.5e-289 962.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EMD68196.1 - 0.00064 19.2 2.1 0.52 9.7 0.1 2.2 2 0 0 2 2 2 2 Intermediate filament protein IncA PF04156.9 EMD68196.1 - 0.018 14.6 2.9 0.47 10.0 0.4 2.5 2 0 0 2 2 2 0 IncA protein CheZ PF04344.8 EMD68196.1 - 0.037 13.6 0.4 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Baculo_PEP_C PF04513.7 EMD68196.1 - 0.078 12.7 0.7 0.63 9.8 0.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EMD68196.1 - 0.2 11.8 2.1 0.25 11.4 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THP2 PF09432.5 EMD68196.1 - 0.26 11.1 2.1 0.24 11.2 0.2 1.9 2 0 0 2 2 2 0 Tho complex subunit THP2 TBPIP PF07106.8 EMD68196.1 - 0.26 10.8 1.2 4.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF869 PF05911.6 EMD68196.1 - 0.52 8.4 3.5 3 5.9 2.5 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Btz PF09405.5 EMD68197.1 - 1.3e-27 96.3 2.4 4e-27 94.8 1.7 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding TFIIF_alpha PF05793.7 EMD68197.1 - 0.4 8.9 7.3 0.62 8.3 5.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4193 PF13834.1 EMD68197.1 - 1.4 9.1 4.4 2.8 8.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) zf-CCCH PF00642.19 EMD68198.1 - 1.8e-05 24.2 0.5 3.2e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1401 PF07180.6 EMD68198.1 - 0.088 12.5 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1401) zf-CCCH_2 PF14608.1 EMD68198.1 - 0.96 9.5 4.3 2 8.5 3.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Na_trans_assoc PF06512.8 EMD68198.1 - 4.9 7.0 18.6 1.6 8.6 1.0 3.1 3 1 0 3 3 3 0 Sodium ion transport-associated Sec1 PF00995.18 EMD68199.1 - 1.5e-132 443.1 0.0 1.7e-132 442.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Syja_N PF02383.13 EMD68199.1 - 0.049 12.3 0.1 0.085 11.6 0.1 1.4 1 0 0 1 1 1 0 SacI homology domain Latexin PF06907.7 EMD68200.1 - 0.06 12.4 0.4 0.062 12.4 0.3 1.1 1 0 0 1 1 1 0 Latexin HET PF06985.6 EMD68201.1 - 1.3e-16 61.0 0.0 2.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Usp PF00582.21 EMD68202.1 - 5.6e-18 65.4 2.5 2.6e-17 63.3 0.3 2.7 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S7 PF00177.16 EMD68203.1 - 4.6e-28 97.6 0.0 7.6e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Baculo_PEP_C PF04513.7 EMD68204.1 - 0.066 13.0 3.9 4 7.2 0.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_88 PF07470.8 EMD68205.1 - 6.3e-11 41.8 0.1 1e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Cellulase PF00150.13 EMD68206.1 - 4.4e-12 45.7 6.0 8.7e-11 41.5 4.1 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EMD68207.1 - 1.6e-20 73.1 23.3 4.2e-20 71.7 16.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EMD68207.1 - 0.19 11.8 2.7 0.29 11.2 0.0 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding adh_short_C2 PF13561.1 EMD68208.1 - 5.6e-22 78.6 0.0 6.3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD68208.1 - 2.3e-21 76.4 0.8 2.9e-21 76.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68208.1 - 3e-09 36.8 0.3 4e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 KR domain CcmE PF03100.10 EMD68208.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CcmE EMP24_GP25L PF01105.19 EMD68209.1 - 3.2e-43 147.5 0.0 4e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tyrosinase PF00264.15 EMD68210.1 - 5.3e-54 183.7 0.1 9.1e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Methyltransf_18 PF12847.2 EMD68211.1 - 7.9e-09 36.0 0.1 2.4e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD68211.1 - 6.8e-08 32.9 0.0 5.5e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD68211.1 - 1.1e-07 31.6 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD68211.1 - 2.9e-07 30.7 0.0 8.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD68211.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD68211.1 - 3.7e-05 24.1 0.0 8.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMD68211.1 - 0.00097 18.3 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EMD68211.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 3HCDH_N PF02737.13 EMD68211.1 - 0.034 13.8 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EMD68211.1 - 0.037 14.0 0.1 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_66 PF13199.1 EMD68211.1 - 0.058 11.7 0.0 0.094 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Methyltransf_9 PF08003.6 EMD68211.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SNF2_N PF00176.18 EMD68212.1 - 7.5e-71 238.3 0.0 1.2e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD68212.1 - 1.3e-10 41.0 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lipase_3 PF01764.20 EMD68213.1 - 2.1e-27 95.4 0.0 3.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMD68213.1 - 0.0009 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD68213.1 - 0.0039 17.1 0.2 0.0071 16.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMD68213.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein TPT PF03151.11 EMD68214.1 - 3.2e-05 23.6 4.9 3.2e-05 23.6 3.4 3.1 3 1 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EMD68214.1 - 0.0016 17.4 11.4 0.0095 14.8 7.9 1.9 1 1 0 1 1 1 1 UAA transporter family Jiraiya PF15038.1 EMD68215.1 - 0.022 14.1 0.1 0.03 13.7 0.0 1.3 1 1 0 1 1 1 0 Jiraiya DUF1691 PF07950.6 EMD68215.1 - 0.034 14.0 0.4 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Peptidase_S8 PF00082.17 EMD68216.1 - 1.4e-50 172.0 13.5 2e-50 171.5 9.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD68216.1 - 5.7e-10 39.6 0.0 1.5e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 EMD68217.1 - 9.6e-39 133.2 0.7 1.3e-38 132.7 0.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD68217.1 - 2.5e-07 31.1 0.0 5.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Urb2 PF10441.4 EMD68218.1 - 0.097 12.2 2.0 0.24 10.9 1.4 1.6 1 0 0 1 1 1 0 Urb2/Npa2 family COesterase PF00135.23 EMD68219.1 - 4.4e-74 250.1 0.0 6.1e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMD68219.1 - 2.7e-05 23.4 0.8 0.00016 20.9 1.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMD68219.1 - 9.9e-05 22.0 0.0 0.00036 20.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EMD68219.1 - 0.0021 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EMD68219.1 - 0.0075 16.1 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD68219.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EMD68221.1 - 1.8e-09 37.3 12.5 2.8e-09 36.7 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EMD68222.1 - 2e-20 71.6 1.9 2e-20 71.6 1.3 2.4 2 0 0 2 2 2 1 Copper fist DNA binding domain MRP-L28 PF09812.4 EMD68224.1 - 0.14 11.9 1.8 0.19 11.5 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Mif2_N PF15624.1 EMD68224.1 - 0.14 12.7 4.8 0.19 12.3 3.3 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal WD40 PF00400.27 EMD68228.1 - 1.1e-79 259.6 23.1 3.4e-13 48.9 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMD68228.1 - 4.1e-08 31.8 0.3 0.00034 18.8 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMD68228.1 - 1.2e-05 24.3 0.5 0.86 8.2 0.0 3.4 2 2 0 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EMD68228.1 - 0.054 11.7 0.1 5.6 5.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain bZIP_1 PF00170.16 EMD68228.1 - 0.097 12.6 0.4 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor CLASP_N PF12348.3 EMD68229.1 - 1.7e-07 30.8 1.4 2.6e-05 23.6 0.4 2.8 2 1 1 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 EMD68229.1 - 1e-05 25.7 1.9 1.8 8.8 0.0 4.3 3 2 2 5 5 5 3 HEAT repeats Adaptin_N PF01602.15 EMD68229.1 - 2.3e-05 22.9 1.6 0.035 12.4 0.2 3.0 2 2 1 3 3 3 2 Adaptin N terminal region IncA PF04156.9 EMD68229.1 - 2.7e-05 23.8 2.5 2.7e-05 23.8 1.8 2.5 3 1 0 3 3 3 1 IncA protein HEAT PF02985.17 EMD68229.1 - 0.00019 21.2 1.2 17 5.7 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EMD68229.1 - 0.003 17.9 1.1 41 4.8 0.1 4.8 3 1 1 4 4 4 0 HEAT-like repeat DUF3647 PF12363.3 EMD68229.1 - 0.017 15.1 0.7 11 6.1 0.1 3.0 2 0 0 2 2 2 0 Phage protein DivIC PF04977.10 EMD68229.1 - 0.062 12.7 10.5 0.052 13.0 3.8 2.8 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 EMD68229.1 - 0.1 10.4 1.3 0.18 9.6 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMS19_N PF14500.1 EMD68229.1 - 0.21 10.8 3.9 0.53 9.5 0.2 3.2 2 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II APG6 PF04111.7 EMD68229.1 - 1.1 8.1 21.5 0.073 12.1 7.2 2.9 2 1 1 3 3 3 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EMD68229.1 - 2.5 8.1 14.0 1 9.3 3.8 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EMD68229.1 - 7 6.4 9.2 0.19 11.4 1.1 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Erythro_esteras PF05139.9 EMD68229.1 - 7.4 5.6 10.1 4 6.5 1.4 2.7 3 0 0 3 3 3 0 Erythromycin esterase G-gamma PF00631.17 EMD68229.1 - 8.6 6.1 8.2 6.7 6.5 0.5 3.4 3 0 0 3 3 3 0 GGL domain Aminotran_1_2 PF00155.16 EMD68230.1 - 1.5e-36 126.1 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DHBP_synthase PF00926.14 EMD68231.1 - 2.8e-71 238.7 0.0 1.1e-70 236.8 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Xan_ur_permease PF00860.15 EMD68232.1 - 4.9e-24 84.5 32.8 4.3e-23 81.4 21.0 2.6 2 1 0 2 2 2 1 Permease family DUF607 PF04678.8 EMD68233.1 - 2.4e-45 154.6 1.0 2.4e-45 154.6 0.7 2.5 2 1 0 2 2 2 1 Protein of unknown function, DUF607 UPF0233 PF06781.7 EMD68233.1 - 0.073 12.6 0.3 0.073 12.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) RRM_1 PF00076.17 EMD68235.1 - 2.2e-80 264.2 4.2 2.2e-19 68.8 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD68235.1 - 3.6e-55 183.8 1.1 4.7e-14 52.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD68235.1 - 2.3e-37 126.6 0.2 1.2e-07 31.4 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMD68235.1 - 9.7e-29 98.8 3.2 2.9e-28 97.3 0.7 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.3 EMD68235.1 - 0.00013 22.1 0.0 0.75 10.0 0.0 3.5 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EMD68235.1 - 0.0017 18.0 4.0 3.8 7.3 0.1 4.1 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EMD68235.1 - 0.0035 17.0 0.1 12 5.7 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EMD68235.1 - 0.025 14.0 1.7 11 5.6 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain TC1 PF15063.1 EMD68235.1 - 0.07 12.6 0.1 11 5.6 0.0 2.8 2 0 0 2 2 2 0 Thyroid cancer protein 1 FBPase PF00316.15 EMD68236.1 - 4.5e-121 403.6 0.0 5.2e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Transket_pyr PF02779.19 EMD68237.1 - 2.7e-64 215.9 0.0 5.6e-64 214.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EMD68237.1 - 4e-55 186.6 0.0 6.6e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component BSD PF03909.12 EMD68238.1 - 3.1e-22 78.0 0.4 5.9e-14 51.5 0.0 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EMD68238.1 - 1.6e-17 62.8 0.4 2.8e-16 58.9 0.1 2.6 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Proteasome_A_N PF10584.4 EMD68240.1 - 0.1 11.9 0.2 0.23 10.7 0.1 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF1992 PF09350.5 EMD68241.1 - 2.9e-24 84.6 0.2 6.2e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) ScdA_N PF04405.9 EMD68242.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) RRF PF01765.14 EMD68243.1 - 6.2e-26 90.8 0.1 7.9e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF3176 PF11374.3 EMD68246.1 - 5.9e-34 116.2 1.1 1.2e-33 115.2 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) COX2-transmemb PF09125.5 EMD68246.1 - 0.016 14.7 0.8 0.037 13.5 0.6 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Diphthamide_syn PF01866.12 EMD68247.1 - 0.068 12.3 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein DUF3176 PF11374.3 EMD68248.1 - 3.3e-39 133.2 0.6 7.1e-39 132.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3153 PF11353.3 EMD68248.1 - 0.63 9.4 2.7 18 4.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3153) DctQ PF04290.7 EMD68248.1 - 2.6 7.8 7.9 25 4.6 2.6 2.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component EspF PF04806.7 EMD68248.1 - 8.6 6.6 15.0 0.16 12.1 0.2 3.0 2 1 0 2 2 2 0 EspF protein repeat Sugar_tr PF00083.19 EMD68249.1 - 1.5e-74 251.1 9.4 1.9e-74 250.9 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68249.1 - 5e-33 114.2 12.7 4e-29 101.4 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD68249.1 - 7.4e-05 21.3 1.5 7.4e-05 21.3 1.0 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.14 EMD68249.1 - 0.00017 20.2 0.7 0.00035 19.2 0.5 1.5 1 0 0 1 1 1 1 LacY proton/sugar symporter TRI12 PF06609.8 EMD68249.1 - 0.014 13.6 2.3 0.016 13.4 0.9 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_3 PF05106.7 EMD68249.1 - 0.091 12.7 1.7 0.44 10.5 0.5 2.6 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) IlvN PF07991.7 EMD68250.1 - 5.3e-48 162.4 0.0 1.1e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EMD68250.1 - 2.6e-45 153.9 0.0 3.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EMD68250.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMD68250.1 - 0.039 14.3 0.4 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.21 EMD68251.1 - 1.8e-38 131.1 0.0 2.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD68251.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RibD_C PF01872.12 EMD68252.1 - 4.1e-34 117.9 0.0 4.8e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF218 PF02698.12 EMD68253.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 DUF218 domain Chitin_synth_1 PF01644.12 EMD68255.1 - 5.1e-67 224.7 0.0 7.4e-67 224.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMD68255.1 - 1.9e-28 97.9 0.0 5.4e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMD68255.1 - 1.2e-24 86.6 0.0 8.2e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMD68255.1 - 1.5e-12 47.6 1.1 1.6e-11 44.2 0.1 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD68255.1 - 2.1e-07 30.9 0.0 5.6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2264 PF10022.4 EMD68256.1 - 1.1e-132 442.1 0.4 1.7e-132 441.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.13 EMD68257.1 - 1.1e-14 53.9 0.7 1.1e-14 53.9 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EMD68258.1 - 1.6e-08 34.2 7.9 2.5e-08 33.5 4.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMD68258.1 - 4.2e-07 29.9 4.3 1.1e-06 28.6 3.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD68258.1 - 0.0003 20.7 7.6 0.00069 19.5 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD68258.1 - 0.00077 19.1 4.4 0.00077 19.1 3.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMD68258.1 - 0.0031 17.1 6.2 0.0031 17.1 4.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD68258.1 - 0.029 14.0 6.0 0.06 13.0 4.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD68258.1 - 0.048 13.4 6.1 0.056 13.2 3.2 1.7 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EMD68258.1 - 0.071 12.5 7.9 0.15 11.5 5.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 EMD68258.1 - 0.091 12.5 2.6 0.16 11.7 1.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Hexapep PF00132.19 EMD68259.1 - 1.3e-10 40.2 9.3 0.00036 19.9 2.0 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD68259.1 - 4.3e-06 26.1 5.3 0.05 13.1 0.0 3.7 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase FliG_C PF01706.11 EMD68259.1 - 0.17 11.9 0.3 0.28 11.1 0.2 1.2 1 0 0 1 1 1 0 FliG C-terminal domain DUF2890 PF11081.3 EMD68260.1 - 0.28 11.2 2.9 0.31 11.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) S100PBPR PF15427.1 EMD68260.1 - 8.3 5.3 7.6 9.9 5.1 5.3 1.0 1 0 0 1 1 1 0 S100P-binding protein SAPS PF04499.10 EMD68261.1 - 5.5e-190 632.0 0.0 1.5e-189 630.5 0.0 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Arm PF00514.18 EMD68261.1 - 0.03 14.1 0.1 23 5.0 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Snf7 PF03357.16 EMD68262.1 - 1.9e-45 154.3 12.5 2.2e-45 154.1 8.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EMD68262.1 - 0.0032 16.9 10.7 0.012 15.0 7.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) HSDR_N PF04313.9 EMD68262.1 - 0.012 15.3 1.5 0.012 15.3 1.0 1.5 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Reo_sigmaC PF04582.7 EMD68262.1 - 0.017 14.2 3.8 0.071 12.2 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EMD68262.1 - 0.033 13.9 0.0 0.033 13.9 0.0 3.6 2 1 1 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 EMD68262.1 - 0.038 13.6 10.6 0.067 12.8 7.2 1.4 1 1 0 1 1 1 0 Mnd1 family NPV_P10 PF05531.7 EMD68262.1 - 0.044 14.0 11.9 0.64 10.3 0.9 3.3 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1409 PF07197.7 EMD68262.1 - 0.05 13.6 0.4 0.97 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) MitMem_reg PF13012.1 EMD68262.1 - 0.071 13.1 4.8 0.23 11.5 3.3 1.8 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function AAA_13 PF13166.1 EMD68262.1 - 0.097 11.1 6.0 0.12 10.7 4.1 1.2 1 0 0 1 1 1 0 AAA domain FliD_C PF07195.7 EMD68262.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Allexi_40kDa PF05549.6 EMD68262.1 - 0.13 11.5 2.8 0.51 9.5 0.2 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1395 PF07160.7 EMD68262.1 - 0.14 11.6 6.9 0.23 10.9 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) DUF3584 PF12128.3 EMD68262.1 - 0.14 9.4 9.6 0.18 9.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EMD68262.1 - 0.2 11.2 7.2 2.1 7.8 5.0 2.1 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 EMD68262.1 - 0.26 10.2 9.1 0.34 9.8 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMD68262.1 - 0.27 10.2 8.0 0.35 9.8 5.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EMD68262.1 - 0.41 10.5 3.3 7.6 6.5 0.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) OmpH PF03938.9 EMD68262.1 - 0.42 10.5 16.4 1.6 8.6 11.3 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 EMD68262.1 - 0.47 10.2 8.1 0.14 11.9 3.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF342 PF03961.8 EMD68262.1 - 0.64 8.3 11.0 2.2 6.6 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Cob_adeno_trans PF01923.13 EMD68262.1 - 1 9.1 5.4 2.1 8.0 1.3 2.1 1 1 2 3 3 3 0 Cobalamin adenosyltransferase TBPIP PF07106.8 EMD68262.1 - 1 8.8 14.4 4.2 6.8 3.8 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliJ PF02050.11 EMD68262.1 - 1 9.3 15.8 3.5 7.7 2.0 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein FlxA PF14282.1 EMD68262.1 - 1.3 9.0 18.1 0.72 9.8 8.3 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 EMD68262.1 - 1.3 9.5 9.3 1.3 9.5 0.0 3.5 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) NYD-SP28_assoc PF14775.1 EMD68262.1 - 1.3 8.7 7.2 0.47 10.1 1.1 2.7 3 0 0 3 3 2 0 Sperm tail C-terminal domain DUF4407 PF14362.1 EMD68262.1 - 2 7.2 9.4 3 6.7 6.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.14 EMD68262.1 - 2.1 7.8 9.7 2.8 7.4 5.3 2.0 1 1 1 2 2 2 0 GrpE Laminin_II PF06009.7 EMD68262.1 - 3.1 7.5 10.6 18 5.1 3.8 2.2 1 1 1 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.3 EMD68262.1 - 4.2 7.2 13.9 2.2 8.1 0.9 3.2 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Suc_Fer-like PF06999.7 EMD68263.1 - 6.4e-31 108.1 0.0 1.3e-29 103.8 0.0 2.6 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EMD68263.1 - 4.1 7.2 5.4 0.53 10.0 0.4 2.0 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide HET PF06985.6 EMD68265.1 - 1.3e-24 86.9 0.2 2.2e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-TAZ PF02135.11 EMD68265.1 - 0.0081 16.1 0.7 0.025 14.5 0.5 1.8 1 0 0 1 1 1 1 TAZ zinc finger HTH_psq PF05225.11 EMD68266.1 - 1.8e-06 27.3 0.2 2.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EMD68266.1 - 4.5e-06 26.3 1.0 4.7e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 EMD68266.1 - 0.0063 16.6 0.3 0.0079 16.3 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMD68266.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.7 EMD68266.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Cdc6_C PF09079.6 EMD68266.1 - 0.07 12.8 0.0 4.3 7.1 0.0 2.2 1 1 1 2 2 2 0 CDC6, C terminal HTH_Tnp_1 PF01527.15 EMD68266.1 - 0.08 12.9 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Transposase HTH_23 PF13384.1 EMD68266.1 - 0.088 12.4 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain HTH_36 PF13730.1 EMD68266.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.16 EMD68266.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DDRGK PF09756.4 EMD68267.1 - 2.4 7.5 9.5 2.8 7.3 6.6 1.1 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 EMD68267.1 - 3.8 5.6 7.1 3.9 5.6 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Spb1_C PF07780.7 EMD68267.1 - 7.3 6.0 15.3 8.3 5.8 10.6 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain DUF2148 PF09918.4 EMD68268.1 - 0.045 13.4 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Rif1_N PF12231.3 EMD68269.1 - 2.1e-105 352.7 0.6 3.1e-105 352.1 0.4 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 EMD68270.1 - 2.1e-115 386.0 0.1 2.5e-115 385.8 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Tht1 PF04163.7 EMD68271.1 - 6.7e-05 21.4 14.4 0.0019 16.7 10.0 2.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein TCTP PF00838.12 EMD68271.1 - 0.039 13.9 1.4 0.073 13.0 1.0 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein CK2S PF15011.1 EMD68271.1 - 0.14 11.9 3.7 0.39 10.4 1.9 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF948 PF06103.6 EMD68271.1 - 0.24 11.2 5.6 0.2 11.5 0.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NYD-SP28 PF14772.1 EMD68271.1 - 0.42 10.7 5.2 4.7 7.3 2.5 2.4 1 1 1 2 2 2 0 Sperm tail Baculo_PEP_C PF04513.7 EMD68271.1 - 0.7 9.7 7.6 0.48 10.2 1.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KfrA_N PF11740.3 EMD68271.1 - 9.4 6.7 7.4 2.7 8.4 0.3 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Ribosomal_L6 PF00347.18 EMD68272.1 - 3.8e-25 88.1 0.0 2e-12 47.4 0.0 3.4 2 2 0 2 2 2 2 Ribosomal protein L6 PgpA PF04608.8 EMD68273.1 - 0.045 13.5 0.6 0.045 13.5 0.4 2.8 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A Peptidase_S64 PF08192.6 EMD68274.1 - 0.0062 14.9 0.5 0.011 14.1 0.3 1.5 1 1 0 1 1 1 1 Peptidase family S64 zf-C2H2_2 PF12756.2 EMD68275.1 - 9.2e-33 112.3 16.1 1.2e-26 92.6 3.6 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMD68275.1 - 6.6e-10 38.8 16.1 2.8e-05 24.1 2.4 4.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMD68275.1 - 4.4e-07 29.8 10.8 4.6e-06 26.6 3.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-DBF PF07535.7 EMD68275.1 - 0.032 13.9 6.3 0.13 11.9 0.5 3.4 3 0 0 3 3 3 0 DBF zinc finger Mso1_Sec1_bdg PF14475.1 EMD68275.1 - 0.063 12.6 0.7 1.3 8.4 0.0 3.0 2 0 0 2 2 2 0 Sec1-binding region of Mso1 zf-C2H2 PF00096.21 EMD68275.1 - 0.22 11.9 24.6 0.21 11.9 0.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD68275.1 - 1.4 8.9 11.7 0.73 9.8 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.7 EMD68275.1 - 3 7.6 11.2 2.9 7.6 0.1 3.3 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) HECT PF00632.20 EMD68276.1 - 9e-71 238.6 0.0 8.9e-70 235.3 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) NOA36 PF06524.7 EMD68277.1 - 0.014 14.7 4.1 0.021 14.1 2.8 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EMD68277.1 - 0.36 11.0 10.3 0.81 9.9 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EMD68277.1 - 0.49 8.2 9.6 0.67 7.8 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EMD68277.1 - 0.54 9.7 10.1 1 8.8 7.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin ANAPC15 PF15243.1 EMD68277.1 - 5.5 7.1 14.4 15 5.7 10.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nuc_sug_transp PF04142.10 EMD68280.1 - 9.8e-83 276.9 7.9 1.8e-82 276.1 5.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.11 EMD68280.1 - 7.3e-45 153.5 0.0 1.9e-44 152.1 0.0 1.7 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EMD68280.1 - 1.1e-23 83.5 0.0 2.6e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD68280.1 - 4.6e-10 39.2 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD68280.1 - 1.3e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EmrE PF13536.1 EMD68280.1 - 5.1e-07 29.8 3.1 5.1e-07 29.8 2.2 2.4 2 0 0 2 2 1 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD68280.1 - 0.00012 22.1 6.9 0.00012 22.1 4.8 2.6 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EMD68280.1 - 0.00023 20.1 15.4 0.00023 20.1 10.7 2.4 1 1 2 3 3 3 1 UAA transporter family TPT PF03151.11 EMD68280.1 - 0.00026 20.6 6.5 0.00026 20.6 4.5 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family HHH_5 PF14520.1 EMD68280.1 - 0.00041 20.4 0.0 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_23 PF13476.1 EMD68280.1 - 0.08 13.2 1.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD68280.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain HET PF06985.6 EMD68281.1 - 6.2e-32 110.6 0.9 1.4e-31 109.4 0.6 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_25 PF13481.1 EMD68281.1 - 0.035 13.5 0.4 0.087 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain tRNA-synt_2c PF01411.14 EMD68281.1 - 0.091 11.0 0.1 0.14 10.3 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) ABC2_membrane PF01061.19 EMD68282.1 - 7.9e-89 296.3 53.3 8e-49 165.6 14.7 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EMD68282.1 - 7.2e-36 123.4 0.0 1.6e-16 60.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMD68282.1 - 1.4e-34 117.7 0.2 2.4e-28 97.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EMD68282.1 - 7.2e-14 51.5 42.0 6.5e-07 28.7 8.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EMD68282.1 - 6.9e-07 28.8 0.1 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 EMD68282.1 - 1.4e-06 28.2 0.2 5.4e-06 26.3 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_17 PF13207.1 EMD68282.1 - 2.7e-05 24.9 0.0 0.024 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD68282.1 - 2.7e-05 23.3 0.0 0.0002 20.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EMD68282.1 - 0.00013 22.0 0.2 0.43 10.5 0.1 3.2 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMD68282.1 - 0.00016 21.7 0.3 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EMD68282.1 - 0.00032 20.2 0.1 0.0048 16.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD68282.1 - 0.00066 19.1 0.2 0.035 13.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMD68282.1 - 0.0034 17.5 0.4 0.22 11.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMD68282.1 - 0.0073 15.9 1.3 0.17 11.5 0.4 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMD68282.1 - 0.0074 16.5 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMD68282.1 - 0.014 15.3 0.2 0.014 15.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMD68282.1 - 0.019 14.4 0.1 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EMD68282.1 - 0.027 14.3 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMD68282.1 - 0.047 13.6 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EMD68282.1 - 0.058 13.1 0.5 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 EMD68282.1 - 0.074 12.4 0.3 3.2 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EMD68282.1 - 0.075 12.6 1.1 0.25 10.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EMD68282.1 - 0.12 12.5 0.4 4.1 7.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase PEPCK_ATP PF01293.15 EMD68283.1 - 2.9e-217 721.7 0.0 3.3e-217 721.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EMD68283.1 - 0.014 15.7 0.7 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMD68283.1 - 0.022 14.6 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMD68283.1 - 0.034 13.5 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMD68283.1 - 0.048 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FAD_binding_4 PF01565.18 EMD68284.1 - 8.8e-23 80.3 0.1 1.7e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD68284.1 - 3.4e-05 23.6 0.1 0.0001 22.1 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like DUF4220 PF13968.1 EMD68285.1 - 0.16 11.0 0.5 0.21 10.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Stn1 PF10451.4 EMD68286.1 - 7.7e-12 44.5 4.4 1.2e-10 40.7 3.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EMD68286.1 - 8.7e-05 22.3 0.5 0.00053 19.7 0.3 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain SHS2_Rpb7-N PF03876.12 EMD68286.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DDRGK PF09756.4 EMD68286.1 - 9.1 5.6 18.5 14 4.9 12.8 1.3 1 0 0 1 1 1 0 DDRGK domain Granulin PF00396.13 EMD68287.1 - 0.0032 17.5 12.4 0.025 14.6 3.7 2.5 2 0 0 2 2 2 2 Granulin DUF2358 PF10184.4 EMD68288.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) dCMP_cyt_deam_1 PF00383.17 EMD68289.1 - 1.6e-14 53.3 0.0 2.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMD68289.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase DnaJ PF00226.26 EMD68290.1 - 2.1e-23 81.8 2.3 7.4e-23 80.0 1.6 2.0 1 0 0 1 1 1 1 DnaJ domain RNase_H2-Ydr279 PF09468.5 EMD68290.1 - 0.53 9.4 22.9 0.59 9.2 4.9 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DNA_pack_N PF02500.10 EMD68290.1 - 8.4 5.8 7.4 0.39 10.1 0.4 2.0 1 1 0 2 2 2 0 Probable DNA packing protein, N-terminus SMN PF06003.7 EMD68291.1 - 7.5 5.5 10.6 9.6 5.2 7.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3816 PF12822.2 EMD68292.1 - 0.9 9.4 18.9 0.48 10.2 1.2 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3816) CENP-F_leu_zip PF10473.4 EMD68294.1 - 4.9e-05 23.2 18.4 0.0028 17.5 9.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EMD68294.1 - 0.0016 18.0 7.0 0.14 11.9 0.1 3.8 3 1 0 3 3 3 1 Homeobox associated leucine zipper AAA_13 PF13166.1 EMD68294.1 - 0.0039 15.7 4.6 0.0055 15.2 3.2 1.1 1 0 0 1 1 1 1 AAA domain WEMBL PF05701.6 EMD68294.1 - 0.0057 15.1 14.1 0.0083 14.6 9.8 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ATG16 PF08614.6 EMD68294.1 - 0.006 16.4 8.7 0.011 15.5 6.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EMD68294.1 - 0.0099 15.4 9.6 0.018 14.6 6.6 1.5 1 0 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 EMD68294.1 - 0.018 15.0 14.2 1.1 9.3 0.2 3.6 3 0 0 3 3 3 0 bZIP transcription factor Reo_sigmaC PF04582.7 EMD68294.1 - 0.018 14.2 0.2 0.034 13.3 0.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EMD68294.1 - 0.022 14.2 10.6 0.28 10.7 4.4 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliJ PF02050.11 EMD68294.1 - 0.053 13.5 8.7 0.057 13.4 1.3 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF904 PF06005.7 EMD68294.1 - 0.089 13.0 15.4 0.19 12.0 3.6 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) GAS PF13851.1 EMD68294.1 - 0.1 11.7 13.7 0.83 8.8 9.0 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EMD68294.1 - 0.11 12.4 13.0 0.48 10.4 3.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 EMD68294.1 - 0.12 11.3 3.9 0.19 10.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EzrA PF06160.7 EMD68294.1 - 0.12 10.4 8.1 0.3 9.2 5.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF342 PF03961.8 EMD68294.1 - 0.17 10.2 7.3 0.13 10.5 4.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EMD68294.1 - 0.18 10.4 11.9 0.45 9.1 8.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.7 EMD68294.1 - 0.18 10.2 3.9 0.24 9.7 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin_2 PF01920.15 EMD68294.1 - 0.18 11.5 13.7 1.3 8.8 0.1 3.0 2 1 1 3 3 2 0 Prefoldin subunit APG6 PF04111.7 EMD68294.1 - 0.21 10.6 13.5 0.021 13.8 3.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4559 PF15112.1 EMD68294.1 - 0.22 10.6 4.2 0.34 10.0 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF972 PF06156.8 EMD68294.1 - 0.33 11.3 10.7 6.5 7.1 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 EMD68294.1 - 0.34 10.9 11.2 0.73 9.8 7.8 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 EMD68294.1 - 0.35 10.6 6.1 7.7 6.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EMD68294.1 - 0.39 10.8 6.8 14 5.8 0.1 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Macoilin PF09726.4 EMD68294.1 - 0.51 8.5 9.8 0.66 8.1 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EMD68294.1 - 0.55 10.6 3.2 1.5 9.2 0.8 2.8 1 1 1 3 3 2 0 SlyX Bacillus_HBL PF05791.6 EMD68294.1 - 0.57 9.5 4.2 2.7 7.3 0.1 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4201 PF13870.1 EMD68294.1 - 0.71 9.2 12.3 0.63 9.4 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Microtub_assoc PF07989.6 EMD68294.1 - 0.83 9.5 6.1 0.16 11.7 1.3 2.0 2 0 0 2 2 1 0 Microtubule associated DUF4200 PF13863.1 EMD68294.1 - 0.83 9.6 13.3 0.032 14.1 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Bap31 PF05529.7 EMD68294.1 - 0.87 9.0 9.7 0.31 10.4 2.2 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DivIVA PF05103.8 EMD68294.1 - 1.1 9.3 11.3 10 6.1 0.2 2.5 1 1 1 2 2 2 0 DivIVA protein Erp_C PF06780.6 EMD68294.1 - 1.1 9.0 9.2 0.49 10.2 1.7 2.4 1 1 1 2 2 2 0 Erp protein C-terminus CCDC155 PF14662.1 EMD68294.1 - 1.1 8.8 15.1 9 5.8 10.7 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 EMD68294.1 - 1.2 8.7 10.2 4.7 6.7 0.2 3.5 1 1 2 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 EMD68294.1 - 1.4 8.8 16.4 1.6 8.5 0.5 3.6 3 1 0 4 4 3 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.4 EMD68294.1 - 2.1 7.4 10.9 1.5 7.9 0.1 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Syntaxin-6_N PF09177.6 EMD68294.1 - 2.5 8.5 5.7 24 5.4 0.7 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Uds1 PF15456.1 EMD68294.1 - 2.7 8.0 12.3 4.1 7.4 7.7 1.9 1 1 0 1 1 1 0 Up-regulated During Septation ERM PF00769.14 EMD68294.1 - 2.7 7.4 21.0 7.5 6.0 14.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ax_dynein_light PF10211.4 EMD68294.1 - 3.2 7.5 14.0 0.14 11.9 3.1 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain ADIP PF11559.3 EMD68294.1 - 3.9 7.3 12.8 2 8.3 4.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 EMD68294.1 - 4.3 8.1 6.7 2.4 8.9 2.5 2.1 2 1 1 3 3 2 0 Occludin homology domain TPR_MLP1_2 PF07926.7 EMD68294.1 - 5.2 6.8 14.6 30 4.3 10.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EMD68294.1 - 7 4.3 7.1 19 2.9 4.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.1 EMD68294.1 - 9.1 6.2 14.1 14 5.6 4.6 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Acid_PPase PF12689.2 EMD68295.1 - 3.7e-21 75.5 0.0 4.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Exo_endo_phos PF03372.18 EMD68295.1 - 0.14 12.0 0.2 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family G_glu_transpept PF01019.16 EMD68296.1 - 2.5e-144 481.5 0.0 3.2e-144 481.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3356 PF11836.3 EMD68296.1 - 0.05 13.3 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) RF-1 PF00472.15 EMD68297.1 - 3.1e-35 120.4 2.6 6.6e-35 119.3 1.8 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EMD68297.1 - 1.2e-31 108.8 0.0 3.6e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 PCRF domain UQ_con PF00179.21 EMD68299.1 - 9.6e-35 119.0 0.1 1.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.10 EMD68300.1 - 7.3e-104 346.5 0.3 8.8e-104 346.2 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EMD68300.1 - 1.6e-08 34.0 0.8 2.1e-08 33.7 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DEAD PF00270.24 EMD68301.1 - 6e-40 136.4 0.1 9.1e-40 135.9 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD68301.1 - 9.5e-21 73.4 0.0 2.3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD68301.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1206 PF06724.6 EMD68302.1 - 0.12 12.1 0.2 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) TLD PF07534.11 EMD68303.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 TLD Dfp1_Him1_M PF08630.5 EMD68304.1 - 1.9e-37 127.8 0.1 4.9e-37 126.5 0.1 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EMD68304.1 - 1.5e-23 82.2 0.6 2.5e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EMD68304.1 - 0.00034 20.6 0.0 0.0039 17.3 0.0 2.5 2 1 1 3 3 3 1 BRCA1 C Terminus (BRCT) domain Antimicrobial_7 PF08102.6 EMD68304.1 - 0.059 13.3 1.2 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Scorpion antimicrobial peptide HNH PF01844.18 EMD68304.1 - 0.15 11.9 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 HNH endonuclease TMEM247 PF15444.1 EMD68304.1 - 3.3 7.4 7.3 8.6 6.1 2.1 2.4 1 1 1 2 2 2 0 Transmembrane protein 247 APG12 PF04110.8 EMD68305.1 - 8.2e-26 90.0 0.0 9.8e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EMD68305.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.21 EMD68307.1 - 1.5e-51 173.4 0.0 1.7e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD68307.1 - 2.4e-05 24.0 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD68307.1 - 0.083 12.7 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 RWD domain Sulfatase PF00884.18 EMD68308.1 - 1.3e-56 192.0 0.0 1.7e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EMD68308.1 - 2.4e-21 75.2 0.3 9.7e-21 73.3 0.2 2.1 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EMD68308.1 - 2.1e-05 24.0 0.1 0.00039 19.8 0.1 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMD68308.1 - 0.0016 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EMD68308.1 - 0.022 14.9 0.3 0.074 13.2 0.0 2.0 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Metalloenzyme PF01676.13 EMD68308.1 - 0.063 12.6 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Metalloenzyme superfamily Pkinase PF00069.20 EMD68310.1 - 4.5e-45 153.8 0.0 7e-44 149.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD68310.1 - 7.7e-31 107.0 0.0 1.1e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD68310.1 - 5.9e-05 22.1 0.0 0.00013 20.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMD68310.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Piwi PF02171.12 EMD68310.1 - 0.044 12.7 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Piwi domain MadL PF03817.8 EMD68310.1 - 0.23 11.3 0.3 0.42 10.4 0.2 1.4 1 0 0 1 1 1 0 Malonate transporter MadL subunit Aldose_epim PF01263.15 EMD68311.1 - 7.8e-42 143.4 0.0 8.7e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pox_A6 PF04924.7 EMD68311.1 - 0.043 12.6 0.1 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein MFS_1 PF07690.11 EMD68313.1 - 2.4e-28 98.8 16.1 3.9e-28 98.1 11.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68313.1 - 3.1e-09 35.9 17.6 3.9e-06 25.7 1.2 3.3 3 1 1 4 4 4 3 Sugar (and other) transporter PUCC PF03209.10 EMD68313.1 - 0.0015 17.3 1.9 0.0044 15.8 0.0 2.4 3 0 0 3 3 3 1 PUCC protein BT1 PF03092.11 EMD68313.1 - 0.11 11.2 4.5 2.4 6.7 0.1 2.4 2 1 1 3 3 3 0 BT1 family AMP-binding PF00501.23 EMD68315.1 - 1.8e-98 329.6 0.0 2.2e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD68315.1 - 5.6e-14 52.8 0.5 1.4e-13 51.5 0.3 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 EMD68316.1 - 2e-37 128.4 1.3 3.9e-37 127.4 0.9 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_oxygenase PF13434.1 EMD68317.1 - 8e-50 169.6 0.0 9.1e-49 166.1 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMD68317.1 - 0.0032 17.2 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD68317.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD68317.1 - 0.032 13.1 0.0 0.046 12.6 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein ABC_membrane PF00664.18 EMD68318.1 - 4.1e-67 226.4 22.2 3e-36 125.2 1.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD68318.1 - 4.3e-67 224.6 0.1 1.4e-32 112.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD68318.1 - 7.7e-13 48.1 3.8 0.00013 21.3 0.0 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD68318.1 - 1.4e-11 44.8 1.8 0.026 14.4 0.0 4.2 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 EMD68318.1 - 5.6e-10 38.3 1.2 0.00012 20.7 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EMD68318.1 - 3.6e-09 37.4 0.0 0.0012 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD68318.1 - 2.1e-07 31.1 8.7 8.6e-05 22.6 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD68318.1 - 2.6e-07 30.0 1.7 0.0098 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMD68318.1 - 8.4e-07 28.5 0.5 0.15 11.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EMD68318.1 - 4e-06 27.0 1.5 0.4 10.8 0.0 4.3 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EMD68318.1 - 5.5e-06 25.6 0.0 0.052 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EMD68318.1 - 1.8e-05 24.4 2.9 0.45 10.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 EMD68318.1 - 2.8e-05 24.4 0.0 0.22 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EMD68318.1 - 8e-05 23.0 0.2 0.11 12.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMD68318.1 - 0.00013 21.6 0.0 0.57 9.9 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EMD68318.1 - 0.00014 21.7 0.3 0.72 9.7 0.0 3.1 4 0 0 4 4 2 2 AAA domain APS_kinase PF01583.15 EMD68318.1 - 0.00055 19.6 0.1 0.039 13.6 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_10 PF12846.2 EMD68318.1 - 0.00071 19.0 5.2 1.1 8.5 0.0 3.9 4 1 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EMD68318.1 - 0.00078 19.3 0.8 2.8 7.9 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DNA_pol3_beta PF00712.14 EMD68318.1 - 0.0059 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 1 1 DNA polymerase III beta subunit, N-terminal domain DUF87 PF01935.12 EMD68318.1 - 0.0064 16.3 0.3 0.76 9.5 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF87 SRP54 PF00448.17 EMD68318.1 - 0.0071 15.8 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EMD68318.1 - 0.0072 16.0 0.1 9.3 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMD68318.1 - 0.0084 15.2 0.0 2 7.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 EMD68318.1 - 0.015 15.2 0.1 8.5 6.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EMD68318.1 - 0.018 14.9 0.0 14 5.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.17 EMD68318.1 - 0.042 12.7 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 EMD68318.1 - 0.072 12.7 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EMD68318.1 - 0.077 12.0 0.0 9.5 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 EMD68318.1 - 0.099 12.1 0.0 8 5.8 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EMD68318.1 - 0.14 10.7 0.0 1 7.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Acetyltransf_7 PF13508.1 EMD68319.1 - 7.2e-09 35.6 0.0 1.4e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD68319.1 - 8.6e-09 35.3 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMD68319.1 - 0.00039 20.2 0.1 0.00095 19.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD68319.1 - 0.0013 18.8 0.0 0.0058 16.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EMD68320.1 - 3.2e-75 253.1 0.0 4.8e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EMD68320.1 - 1.9e-65 220.7 0.0 3.7e-37 127.7 0.0 2.8 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EMD68320.1 - 3.8e-42 142.3 7.3 4.3e-13 49.3 0.3 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Tyrosinase PF00264.15 EMD68321.1 - 4.6e-27 95.6 0.3 6.2e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase ECH PF00378.15 EMD68323.1 - 1.3e-39 135.8 0.1 9.9e-39 132.9 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family WD40 PF00400.27 EMD68324.1 - 1.2e-60 199.3 27.8 1.6e-11 43.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMD68324.1 - 0.00043 18.5 4.9 0.31 9.1 0.1 3.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMD68324.1 - 0.085 11.1 0.1 3.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain NmrA PF05368.8 EMD68325.1 - 7.5e-14 51.5 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD68325.1 - 2e-08 34.4 0.0 1.1e-05 25.5 0.0 2.5 3 0 0 3 3 3 2 NADH(P)-binding Shikimate_DH PF01488.15 EMD68325.1 - 1.2e-06 28.6 0.0 2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMD68325.1 - 0.093 12.7 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain zf-U1 PF06220.7 EMD68326.1 - 8.1e-22 76.5 3.5 1.1e-21 76.1 2.4 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EMD68326.1 - 0.0094 16.0 3.4 0.02 15.0 2.4 1.5 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 EMD68326.1 - 0.026 14.3 0.1 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) NDUFA12 PF05071.11 EMD68328.1 - 1.1e-10 41.8 0.1 1.1e-10 41.8 0.1 2.0 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 EMD68329.1 - 2.2e-11 43.7 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMD68329.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain HET PF06985.6 EMD68332.1 - 1.1e-38 132.5 1.0 1.8e-38 131.8 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 EMD68332.1 - 9e-28 96.1 0.0 5.4e-11 42.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD68332.1 - 1.5e-24 86.1 0.0 2e-11 44.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD68332.1 - 1.5e-23 81.3 0.0 5.5e-06 25.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EMD68332.1 - 5e-18 63.4 0.0 0.0027 17.7 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMD68332.1 - 1.6e-16 59.9 0.1 9.8e-07 28.8 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) TIR_2 PF13676.1 EMD68332.1 - 0.015 15.3 1.0 7.2 6.8 0.2 3.6 3 1 1 4 4 4 0 TIR domain TPR_12 PF13424.1 EMD68332.1 - 0.071 13.0 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Totivirus_coat PF05518.6 EMD68333.1 - 2.1 6.0 9.7 2.8 5.6 6.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mito_carr PF00153.22 EMD68335.1 - 1.5e-20 72.7 3.6 8.4e-08 31.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 EMD68335.1 - 0.00017 21.5 0.0 0.0025 17.7 0.0 2.4 2 1 0 2 2 2 1 Colicin V production protein NPP1 PF05630.6 EMD68336.1 - 6.3e-60 202.4 3.2 8.4e-60 202.0 2.2 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF4538 PF15061.1 EMD68338.1 - 0.064 12.5 0.1 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DHDPS PF00701.17 EMD68339.1 - 1.9e-42 144.8 0.0 2.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldo_ket_red PF00248.16 EMD68340.1 - 2.8e-65 219.9 0.0 3.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-A20 PF01754.11 EMD68340.1 - 0.16 11.5 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 A20-like zinc finger SPA PF08616.5 EMD68341.1 - 0.083 12.6 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis DUF3328 PF11807.3 EMD68341.1 - 0.12 11.9 0.7 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) MARVEL PF01284.18 EMD68341.1 - 0.22 11.3 3.6 0.36 10.6 2.4 1.6 1 1 0 1 1 1 0 Membrane-associating domain Rtt106 PF08512.7 EMD68342.1 - 1.3e-22 79.5 0.0 2.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CobT PF06213.7 EMD68342.1 - 2.2 7.3 18.1 3.6 6.6 12.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MIP PF00230.15 EMD68343.1 - 1e-49 169.0 12.0 1.3e-49 168.7 8.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein bZIP_2 PF07716.10 EMD68344.1 - 0.04 13.7 3.9 0.056 13.2 2.7 1.2 1 0 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.11 EMD68345.1 - 8e-48 162.9 77.6 2e-41 141.8 37.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68345.1 - 1.8e-11 43.3 33.6 1.4e-07 30.4 9.7 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Glyco_tran_28_C PF04101.11 EMD68346.1 - 3.3e-09 36.6 0.1 5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EMD68346.1 - 3.1e-07 29.3 0.1 7.7e-07 28.0 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EMD68346.1 - 0.0025 17.0 0.0 0.0081 15.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 1 Herpes_TK PF00693.13 EMD68347.1 - 0.04 13.0 0.1 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus UPF0193 PF05250.6 EMD68347.1 - 0.082 12.4 5.0 0.15 11.5 3.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) YceG PF02618.11 EMD68347.1 - 0.13 11.2 0.7 0.19 10.6 0.5 1.1 1 0 0 1 1 1 0 YceG-like family HATPase_c_3 PF13589.1 EMD68349.1 - 3.7e-17 62.2 0.0 8.9e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EMD68349.1 - 1.4e-09 37.7 0.2 4.5e-08 32.8 0.1 2.7 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EMD68349.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1035 PF06281.7 EMD68349.1 - 0.0079 15.9 0.1 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1035) DUF1761 PF08570.5 EMD68350.1 - 2e-25 89.2 1.6 2.3e-25 89.0 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) K_channel_TID PF07941.6 EMD68350.1 - 0.19 11.9 1.9 0.35 11.1 1.3 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CD20 PF04103.10 EMD68350.1 - 0.29 11.0 2.6 0.28 11.0 1.3 1.5 1 1 0 1 1 1 0 CD20-like family Dabb PF07876.7 EMD68351.1 - 1.4e-21 76.7 0.3 1.6e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_L17 PF01196.14 EMD68352.1 - 7.3e-33 113.0 0.1 1.7e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 BBP1_C PF15272.1 EMD68352.1 - 0.068 12.7 0.5 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Ribonuc_red_lgC PF02867.10 EMD68353.1 - 3.1e-217 722.4 0.0 4.2e-217 721.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMD68353.1 - 7.7e-25 86.5 0.0 1.8e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EMD68353.1 - 5.3e-17 62.0 0.0 3.5e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EMD68353.1 - 0.033 12.2 0.0 0.05 11.6 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MMR_HSR1_C PF08438.5 EMD68353.1 - 0.052 13.7 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 GTPase of unknown function C-terminal YCII PF03795.9 EMD68354.1 - 6.8e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain Peptidase_S10 PF00450.17 EMD68356.1 - 2.4e-116 389.3 0.0 3.3e-116 388.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMD68356.1 - 4.1e-05 23.5 0.0 0.00035 20.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family GRA6 PF05084.8 EMD68356.1 - 0.022 14.2 0.3 0.33 10.4 0.0 2.4 1 1 1 2 2 2 0 Granule antigen protein (GRA6) RNA_Me_trans PF04252.8 EMD68357.1 - 1.4e-46 158.3 0.0 1.6e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 EMD68358.1 - 5.8e-24 83.8 0.1 9.5e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Glyco_hydro_63 PF03200.11 EMD68359.1 - 4.1e-197 656.6 0.0 2.4e-195 650.8 0.0 2.0 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMD68359.1 - 0.0011 17.7 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 Trehalase AAA_17 PF13207.1 EMD68360.1 - 1.7e-07 32.0 1.4 2.4e-06 28.3 1.0 2.5 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMD68360.1 - 1.6e-06 27.8 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EMD68360.1 - 5.1e-05 23.5 0.0 0.00096 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMD68360.1 - 0.0004 19.3 0.0 0.00061 18.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EMD68360.1 - 0.00058 20.0 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD68360.1 - 0.001 18.2 0.7 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 EMD68360.1 - 0.0015 17.5 0.0 0.0074 15.2 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 EMD68360.1 - 0.0016 18.4 0.0 0.0063 16.5 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EMD68360.1 - 0.0034 17.2 0.2 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD68360.1 - 0.0046 16.6 0.1 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 EMD68360.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 EMD68360.1 - 0.01 15.2 0.2 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.15 EMD68360.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 EMD68360.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMD68360.1 - 0.034 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMD68360.1 - 0.034 13.3 0.1 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.7 EMD68360.1 - 0.037 13.0 0.1 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMD68360.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EMD68360.1 - 0.067 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 EMD68360.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EMD68360.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMD68360.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMD68360.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 EMD68360.1 - 0.11 12.3 1.4 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Shikimate kinase ArgK PF03308.11 EMD68360.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 EMD68360.1 - 0.15 11.5 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD68360.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EMD68360.1 - 0.19 11.6 0.9 0.31 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain Melibiase PF02065.13 EMD68361.1 - 1.1e-14 53.9 0.0 3.5e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 Melibiase Sugar_tr PF00083.19 EMD68362.1 - 2.6e-79 266.8 31.9 3.1e-79 266.6 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68362.1 - 1.4e-14 53.6 36.0 9.5e-11 41.0 9.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMD68362.1 - 0.021 14.8 5.7 0.59 10.1 0.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) adh_short PF00106.20 EMD68363.1 - 1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD68363.1 - 6.3e-14 52.3 0.0 8.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68363.1 - 6.3e-13 48.7 0.0 9.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD68363.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD68363.1 - 0.0092 14.7 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EMD68363.1 - 0.021 13.8 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EMD68363.1 - 0.025 14.3 0.6 0.78 9.5 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EMD68363.1 - 0.043 13.4 0.1 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EMD68363.1 - 0.045 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 EMD68363.1 - 0.087 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tannase PF07519.6 EMD68364.1 - 9.3e-95 318.0 0.1 2.7e-94 316.5 0.1 1.6 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EMD68364.1 - 3.9e-05 22.9 0.3 0.023 13.8 0.4 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family MOZART1 PF12554.3 EMD68364.1 - 0.018 14.4 0.1 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Abhydrolase_6 PF12697.2 EMD68364.1 - 0.023 14.5 0.2 0.034 14.0 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box PF00646.28 EMD68365.1 - 0.00016 21.2 0.2 0.00032 20.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD68365.1 - 0.0011 18.6 0.6 0.002 17.8 0.4 1.4 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 EMD68366.1 - 2.2e-23 83.0 0.8 2.2e-23 83.0 0.6 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EMD68366.1 - 6.5e-19 68.4 0.1 1.3e-13 50.9 0.0 3.0 2 1 1 3 3 3 2 Acyl transferase domain adh_short_C2 PF13561.1 EMD68366.1 - 3.1e-17 63.1 0.2 7e-17 61.9 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68366.1 - 2.3e-13 50.1 1.0 5.6e-13 48.9 0.3 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMD68366.1 - 1.5e-05 24.6 0.1 7e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD68366.1 - 0.002 16.9 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Med5 PF08689.5 EMD68367.1 - 3.2e-250 832.8 0.0 3.6e-250 832.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Aldo_ket_red PF00248.16 EMD68370.1 - 1.7e-41 141.9 0.0 2.1e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ELFV_dehydrog PF00208.16 EMD68371.1 - 3.1e-84 282.3 1.4 3.9e-84 282.0 1.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EMD68371.1 - 1.6e-47 160.3 0.0 4.3e-47 158.9 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF29 PF01724.11 EMD68372.1 - 0.06 13.1 2.5 0.16 11.8 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF29 FUSC PF04632.7 EMD68372.1 - 0.44 8.9 1.6 0.63 8.3 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3439 PF11921.3 EMD68373.1 - 0.69 9.6 9.0 1.6 8.4 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) adh_short_C2 PF13561.1 EMD68374.1 - 7.3e-28 97.9 0.0 8.7e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD68374.1 - 4.4e-25 88.5 0.0 5.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68374.1 - 3.3e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD68374.1 - 0.061 13.1 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4650 PF15509.1 EMD68375.1 - 0.19 10.6 2.0 0.23 10.3 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Mucin PF01456.12 EMD68375.1 - 0.83 9.4 15.9 1.1 9.0 11.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Coa1 PF08695.5 EMD68376.1 - 8.6e-39 131.6 0.0 1.1e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2157 PF09925.4 EMD68377.1 - 1.4 8.5 5.3 12 5.4 0.3 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) PHD PF00628.24 EMD68378.1 - 5.9e-08 32.2 6.0 1.4e-07 31.0 4.2 1.7 1 0 0 1 1 1 1 PHD-finger Fork_head PF00250.13 EMD68378.1 - 0.0015 18.5 0.1 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Fork head domain PHD_2 PF13831.1 EMD68378.1 - 0.0018 17.5 1.9 0.004 16.4 1.3 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EMD68378.1 - 0.0068 16.1 1.4 0.0068 16.1 1.0 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMD68378.1 - 0.04 13.6 2.4 0.095 12.4 1.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EMD68378.1 - 0.047 12.9 5.0 0.033 13.4 1.7 2.1 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.20 EMD68379.1 - 4.8e-13 48.8 0.0 1.9e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD68379.1 - 3.1e-09 36.3 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EMD68379.1 - 5.4e-09 35.3 4.5 0.13 12.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Kinase-like PF14531.1 EMD68379.1 - 2.4e-05 23.4 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.1 EMD68379.1 - 0.00011 22.5 0.2 1.4 9.5 0.0 3.3 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 EMD68379.1 - 0.0017 18.5 1.1 0.018 15.2 0.1 2.9 2 1 1 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EMD68379.1 - 0.037 14.4 0.1 14 6.1 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EMD68379.1 - 0.1 12.4 0.0 0.68 9.7 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2416 PF10315.4 EMD68380.1 - 0.00012 22.2 0.1 0.00016 21.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DnaJ PF00226.26 EMD68381.1 - 5.4e-24 83.7 1.3 1.1e-23 82.6 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EMD68381.1 - 1.3e-21 76.8 1.7 2e-21 76.2 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Cyto_heme_lyase PF01265.12 EMD68382.1 - 5.1e-86 288.4 0.3 5.8e-86 288.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EMD68383.1 - 3.6e-11 42.9 0.9 9.7e-11 41.5 0.5 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMD68383.1 - 0.0022 18.1 0.1 0.021 15.0 0.0 2.6 3 0 0 3 3 3 1 GHMP kinases C terminal Syntaxin_2 PF14523.1 EMD68384.1 - 1.4e-22 79.5 5.2 1.4e-22 79.5 3.6 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMD68384.1 - 1.1e-17 63.4 3.5 1.1e-17 63.4 2.4 2.4 3 0 0 3 3 2 1 SNARE domain MCPsignal PF00015.16 EMD68384.1 - 0.00025 20.6 8.3 0.056 12.9 1.1 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EMD68384.1 - 0.0018 17.8 0.6 0.0018 17.8 0.4 2.6 3 0 0 3 3 3 1 Synaptobrevin YjgP_YjgQ PF03739.9 EMD68384.1 - 0.016 13.9 0.4 0.027 13.2 0.3 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF651 PF04895.7 EMD68384.1 - 0.044 13.3 2.9 0.054 13.1 0.1 2.4 2 1 1 3 3 3 0 Archaeal protein of unknown function (DUF651) TMPIT PF07851.8 EMD68384.1 - 0.048 12.7 9.8 0.012 14.6 3.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF883 PF05957.8 EMD68384.1 - 0.058 13.8 19.6 0.058 13.7 1.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ODV-E18 PF10717.4 EMD68384.1 - 0.066 12.6 0.4 0.16 11.4 0.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 EMD68384.1 - 0.096 12.7 0.4 0.096 12.7 0.3 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vac_Fusion PF02346.11 EMD68384.1 - 0.1 12.0 0.9 0.83 9.1 0.1 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Syntaxin PF00804.20 EMD68384.1 - 0.41 10.8 15.9 33 4.7 11.0 3.0 1 1 0 1 1 1 0 Syntaxin PMC2NT PF08066.7 EMD68384.1 - 0.44 10.8 4.5 3 8.2 0.1 2.8 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF1664 PF07889.7 EMD68384.1 - 0.62 9.8 8.1 2 8.2 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rifin_STEVOR PF02009.11 EMD68384.1 - 8.8 5.8 10.8 14 5.1 6.2 2.2 1 1 0 2 2 2 0 Rifin/stevor family Ndc1_Nup PF09531.5 EMD68385.1 - 6.1e-130 434.4 0.0 6.9e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rootletin PF15035.1 EMD68385.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion p450 PF00067.17 EMD68386.1 - 1.6e-36 125.8 0.0 3.6e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 DUF1656 PF07869.7 EMD68387.1 - 0.035 13.8 8.3 0.92 9.3 0.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1656) NAD_binding_8 PF13450.1 EMD68388.1 - 1.2e-09 37.9 0.2 2.5e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMD68388.1 - 3.5e-09 36.2 0.4 6.1e-09 35.4 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMD68388.1 - 3.9e-08 32.8 0.0 7.9e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMD68388.1 - 2.5e-06 27.5 1.5 3.6e-05 23.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD68388.1 - 2.8e-06 26.4 3.1 4.6e-06 25.7 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD68388.1 - 4.3e-06 25.4 1.5 4.7e-05 22.0 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMD68388.1 - 1.7e-05 24.0 0.7 3e-05 23.2 0.5 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMD68388.1 - 5.4e-05 22.2 1.0 0.0001 21.3 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD68388.1 - 0.00026 21.3 0.5 0.0014 19.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD68388.1 - 0.00044 20.3 0.1 0.021 14.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD68388.1 - 0.0016 17.4 0.2 0.0027 16.6 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMD68388.1 - 0.0017 17.4 0.8 0.0026 16.8 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Zn_clus PF00172.13 EMD68389.1 - 2.7e-09 36.7 9.4 6.4e-09 35.5 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EMD68389.1 - 0.00069 18.7 9.6 0.0026 16.8 6.7 1.7 1 1 0 1 1 1 1 Aflatoxin regulatory protein DUF506 PF04720.7 EMD68389.1 - 0.033 13.8 1.8 0.44 10.1 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF506) NmrA PF05368.8 EMD68390.1 - 1.2e-14 54.2 0.0 5.6e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EMD68390.1 - 4.5e-12 46.3 0.0 8.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD68390.1 - 0.00049 19.6 0.1 0.0025 17.3 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD68390.1 - 0.029 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EMD68390.1 - 0.042 12.5 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.19 EMD68391.1 - 8.5e-16 57.7 0.0 2.6e-07 29.9 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMD68391.1 - 7.6e-15 54.8 0.0 7.4e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EMD68391.1 - 5.7e-08 32.0 0.0 9.1e-07 28.1 0.0 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMD68391.1 - 1.1e-07 30.6 0.0 0.00016 20.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EMD68391.1 - 3.2e-07 29.5 0.1 6.8e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMD68391.1 - 1.9e-06 27.7 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD68391.1 - 4.5e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD68391.1 - 0.00019 20.6 0.1 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD68391.1 - 0.00024 21.4 0.1 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD68391.1 - 0.00037 19.4 0.0 0.0076 15.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EMD68391.1 - 0.0034 16.5 0.0 0.54 9.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMD68391.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMD68391.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EMD68391.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 EMD68392.1 - 3.8e-11 42.6 0.1 5.3e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD68392.1 - 2.4e-09 37.4 0.1 3.8e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMD68392.1 - 0.00013 21.9 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMD68392.1 - 0.001 18.5 0.1 0.0025 17.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMD68392.1 - 0.065 12.8 0.3 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EMD68392.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EMD68393.1 - 5.2e-08 32.6 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD68393.1 - 5.5e-08 31.8 0.0 8.4e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMD68393.1 - 5.8e-07 28.6 0.0 0.0053 15.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMD68393.1 - 7.1e-05 22.8 0.0 0.00048 20.1 0.1 2.3 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMD68393.1 - 0.0003 20.1 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Methyltransf_2 PF00891.13 EMD68394.1 - 3.5e-44 150.8 0.0 5.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMD68394.1 - 7.6e-06 25.7 0.0 2.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD68394.1 - 9.2e-05 22.9 0.0 0.00031 21.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD68394.1 - 0.0066 16.9 0.0 0.033 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMD68394.1 - 0.14 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase ketoacyl-synt PF00109.21 EMD68395.1 - 2.3e-74 250.0 0.0 4.5e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD68395.1 - 4.8e-52 177.2 0.0 1.7e-51 175.4 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD68395.1 - 5.7e-31 106.8 0.3 1.3e-30 105.7 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EMD68395.1 - 2.6e-25 88.8 0.0 6.3e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EMD68395.1 - 3.5e-22 78.4 6.7 4e-11 43.0 0.6 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EMD68395.1 - 9.2e-14 51.2 0.0 2.1e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMD68395.1 - 1.8e-06 27.9 0.0 6e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68395.1 - 1.3e-05 24.9 0.0 4.8e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.18 EMD68395.1 - 2.2e-05 23.5 0.0 5.9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 EMD68395.1 - 4e-05 23.1 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Abhydrolase_5 PF12695.2 EMD68395.1 - 0.00012 21.8 0.0 1.2 8.8 0.0 3.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Polysacc_synt_2 PF02719.10 EMD68395.1 - 0.037 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein B12D PF06522.6 EMD68395.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit XPA_C PF05181.7 EMD68395.1 - 0.23 11.0 0.3 0.63 9.6 0.2 1.7 1 0 0 1 1 1 0 XPA protein C-terminus Asp PF00026.18 EMD68396.1 - 2.8e-66 223.9 0.9 3.5e-66 223.6 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMD68396.1 - 4e-09 36.6 0.2 4e-09 36.6 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMD68396.1 - 0.0006 20.2 0.2 2.3 8.7 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMD68396.1 - 0.048 13.2 0.0 8.7 5.8 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Ras PF00071.17 EMD68397.1 - 5.8e-55 185.0 0.0 6.8e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD68397.1 - 8.8e-16 58.4 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD68397.1 - 7.1e-07 28.6 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD68397.1 - 0.00072 18.8 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMD68397.1 - 0.0011 18.3 0.1 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMD68397.1 - 0.015 14.7 0.0 2.9 7.3 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EMD68397.1 - 0.033 13.3 0.0 0.04 13.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ufd2P_core PF10408.4 EMD68398.1 - 2.1e-200 667.1 6.8 2.5e-200 666.9 4.7 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMD68398.1 - 2.9e-24 84.8 0.9 8.3e-24 83.3 0.6 1.8 1 0 0 1 1 1 1 U-box domain Cob_adeno_trans PF01923.13 EMD68398.1 - 0.064 13.0 3.7 1.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF1712 PF08217.6 EMD68399.1 - 2e-13 49.4 0.0 4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF1183 PF06682.7 EMD68399.1 - 0.78 9.2 11.5 1.7 8.1 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Formyl_trans_N PF00551.14 EMD68400.1 - 1.8e-27 96.0 0.0 2.3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EMD68400.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3263 PF11662.3 EMD68400.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) zf-C3HC4_3 PF13920.1 EMD68402.1 - 0.0041 16.7 8.8 0.0062 16.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 EMD68402.1 - 1.3 8.2 5.5 7.7 5.7 1.3 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others EamA PF00892.15 EMD68403.1 - 5.6e-18 65.1 23.4 4.5e-09 36.4 2.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family PNGaseA PF12222.3 EMD68404.1 - 3.3e-125 418.3 1.3 5.8e-125 417.5 0.9 1.3 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 EMD68405.1 - 1.5e-24 86.1 0.0 2.2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Polysacc_deac_1 PF01522.16 EMD68407.1 - 2.2e-22 79.0 0.0 5.1e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EMD68407.1 - 0.051 12.5 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase HTH_39 PF14090.1 EMD68407.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rad52_Rad22 PF04098.10 EMD68408.1 - 4.4e-59 198.6 0.1 6.4e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 EMD68408.1 - 0.053 11.7 38.7 0.08 11.1 26.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 EMD68409.1 - 4.2e-23 80.3 5.1 7.7e-09 35.1 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EMD68409.1 - 0.00078 19.2 0.9 0.27 10.9 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EMD68409.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EMD68409.1 - 0.074 11.1 0.1 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Guanylate_kin PF00625.16 EMD68410.1 - 2.6e-60 202.9 0.0 3e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EMD68410.1 - 2e-06 28.0 0.0 7.4e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD68410.1 - 7.3e-06 25.9 0.0 2.5e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD68410.1 - 3.8e-05 24.4 0.0 9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD68410.1 - 3.9e-05 23.7 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EMD68410.1 - 0.00049 20.4 0.0 0.00058 20.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 EMD68410.1 - 0.00099 19.4 0.6 0.011 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMD68410.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMD68410.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMD68410.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMD68410.1 - 0.0018 17.6 0.6 0.78 9.0 0.0 2.3 1 1 1 2 2 2 2 Thymidylate kinase DUF2075 PF09848.4 EMD68410.1 - 0.0024 16.9 0.0 0.047 12.6 0.0 2.0 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EMD68410.1 - 0.0028 17.1 0.1 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 EMD68410.1 - 0.0037 16.7 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EMD68410.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.7 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EMD68410.1 - 0.0061 16.7 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Miro PF08477.8 EMD68410.1 - 0.0066 16.9 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EMD68410.1 - 0.0097 15.8 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EMD68410.1 - 0.011 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EMD68410.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EMD68410.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.5 1 1 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 EMD68410.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 EMD68410.1 - 0.05 12.2 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EMD68410.1 - 0.06 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 EMD68410.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EMD68410.1 - 0.076 12.4 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EMD68410.1 - 0.098 12.2 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EMD68410.1 - 0.1 12.0 0.1 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain YqfD PF06898.6 EMD68410.1 - 0.12 11.0 0.3 5.8 5.4 0.0 2.0 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD AAA_15 PF13175.1 EMD68410.1 - 0.13 11.2 0.3 0.19 10.7 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 EMD68411.1 - 1.4e-31 107.1 4.8 3.7e-10 39.2 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EMD68411.1 - 0.0093 15.6 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A D123 PF07065.9 EMD68412.1 - 6.3e-07 28.7 0.0 0.00018 20.7 0.0 2.1 1 1 1 2 2 2 2 D123 Peptidase_S8 PF00082.17 EMD68413.1 - 2.7e-48 164.5 8.3 3.8e-48 164.0 5.8 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMD68413.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 Pec_lyase_C PF00544.14 EMD68414.1 - 1.8e-40 138.5 9.0 5.2e-40 137.0 6.2 1.7 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMD68414.1 - 0.00019 21.2 9.5 0.0026 17.5 6.1 2.2 1 1 0 1 1 1 1 Right handed beta helix region MRP-S25 PF13741.1 EMD68415.1 - 2.2e-69 233.4 1.0 9.7e-62 208.4 0.9 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EMD68415.1 - 0.013 15.3 1.3 0.045 13.6 0.3 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 EMD68416.1 - 8.1e-13 48.1 0.4 0.00037 20.4 0.0 5.0 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.1 EMD68416.1 - 7.4e-12 44.5 6.1 0.00044 20.3 0.1 6.3 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 EMD68416.1 - 8.7e-11 41.0 0.3 0.0083 16.0 0.0 4.9 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EMD68416.1 - 0.019 14.4 0.8 12 5.4 0.0 4.0 3 2 0 3 3 3 0 PPR repeat OTOS PF15182.1 EMD68418.1 - 0.041 13.5 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Otospiralin BTB PF00651.26 EMD68419.1 - 0.0002 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EMD68420.1 - 3.1e-05 23.9 0.1 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.17 EMD68421.1 - 8.2e-16 57.3 0.1 1.5e-15 56.5 0.0 1.5 2 0 0 2 2 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD68421.1 - 2.8e-11 43.2 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD68421.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lge1 PF11488.3 EMD68421.1 - 0.02 15.0 4.4 0.066 13.4 3.2 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.14 EMD68421.1 - 0.031 12.1 2.0 0.033 12.0 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EAP30 PF04157.11 EMD68421.1 - 0.053 12.6 2.1 0.067 12.3 1.5 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family EMP24_GP25L PF01105.19 EMD68421.1 - 0.095 12.4 6.1 0.14 11.8 4.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CPSF100_C PF13299.1 EMD68421.1 - 0.44 10.7 2.4 0.66 10.1 1.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_27 PF13514.1 EMD68421.1 - 0.57 7.8 8.0 0.7 7.5 5.6 1.0 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.9 EMD68421.1 - 0.9 9.1 9.1 1.3 8.6 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 EMD68421.1 - 1.2 8.1 5.8 1.4 7.8 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EMD68421.1 - 3.6 4.8 9.4 4.5 4.4 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EMD68421.1 - 4.1 6.9 10.5 5.9 6.4 7.3 1.2 1 0 0 1 1 1 0 IncA protein DUF812 PF05667.6 EMD68421.1 - 5.6 5.3 10.1 6.8 5.0 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UQ_con PF00179.21 EMD68422.1 - 1.2e-47 160.8 0.0 1.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD68422.1 - 0.00068 19.3 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMD68422.1 - 0.018 14.8 1.0 0.03 14.2 0.7 1.7 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EMD68423.1 - 9.9e-71 238.2 21.7 9.9e-71 238.2 15.0 1.4 2 0 0 2 2 2 1 Pex19 protein family Rotamase PF00639.16 EMD68423.1 - 0.4 11.4 10.1 1.8 9.3 0.3 2.8 1 1 0 2 2 2 0 PPIC-type PPIASE domain DHHA1 PF02272.14 EMD68423.1 - 0.5 10.0 3.0 1.5 8.5 0.3 2.8 3 0 0 3 3 3 0 DHHA1 domain ABC_tran_2 PF12848.2 EMD68423.1 - 4.8 7.1 18.7 0.085 12.7 0.4 3.2 3 0 0 3 3 3 0 ABC transporter DUF445 PF04286.7 EMD68423.1 - 5.5 6.4 6.7 31 3.9 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF2458 PF10454.4 EMD68423.1 - 8.9 6.1 10.8 1.2 9.0 2.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) AnfO_nitrog PF09582.5 EMD68424.1 - 0.11 11.5 0.3 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Response_reg PF00072.19 EMD68425.1 - 1e-21 77.0 0.1 2.6e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMD68425.1 - 4.7e-21 74.5 0.0 1.3e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EMD68425.1 - 3.3e-11 43.0 0.0 3.5e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EMD68425.1 - 0.004 17.2 0.1 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pyr_redox_3 PF13738.1 EMD68426.1 - 1.4e-25 90.5 0.0 2.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD68426.1 - 2.6e-11 42.4 0.2 4.1e-10 38.4 0.1 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD68426.1 - 3.6e-11 42.9 0.1 3.5e-09 36.5 0.0 3.2 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD68426.1 - 1.9e-07 30.2 0.7 1.1e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMD68426.1 - 3.3e-06 26.2 0.3 0.00035 19.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMD68426.1 - 3.7e-05 22.9 0.2 0.00025 20.2 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EMD68426.1 - 0.00014 21.8 0.0 0.00047 20.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMD68426.1 - 0.00055 19.1 0.0 0.035 13.1 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD68426.1 - 0.00066 18.7 0.0 0.0069 15.3 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EMD68426.1 - 0.0063 15.4 0.2 0.56 8.9 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMD68426.1 - 0.008 15.0 0.0 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EMD68426.1 - 0.01 15.9 0.0 0.29 11.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMD68426.1 - 0.029 14.1 5.5 0.11 12.2 0.1 3.5 4 1 0 4 4 4 0 FAD-NAD(P)-binding Mqo PF06039.10 EMD68426.1 - 0.037 12.1 0.0 2.2 6.3 0.0 2.3 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.19 EMD68426.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMD68426.1 - 0.051 13.9 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EMD68427.1 - 6.4e-29 100.7 38.5 2.3e-20 72.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68427.1 - 1.6e-16 59.9 24.3 6e-12 44.8 3.1 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter Fungal_trans PF04082.13 EMD68428.1 - 5.5e-11 41.8 1.1 9.5e-11 41.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EMD68429.1 - 6.3e-45 153.5 15.6 7.9e-45 153.2 10.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68429.1 - 2.4e-19 69.2 19.1 2.4e-19 69.2 13.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GSDH PF07995.6 EMD68430.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SBBP PF06739.6 EMD68430.1 - 0.0037 17.0 0.0 0.41 10.4 0.0 3.4 3 0 0 3 3 3 1 Beta-propeller repeat NHL PF01436.16 EMD68430.1 - 0.0093 15.8 0.2 9.4 6.4 0.0 3.2 2 0 0 2 2 2 2 NHL repeat Lactonase PF10282.4 EMD68430.1 - 0.1 11.6 0.0 0.88 8.5 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ECH PF00378.15 EMD68431.1 - 1.2e-25 90.0 0.0 1.5e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GvpO PF05800.6 EMD68431.1 - 0.071 13.0 0.1 9.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO Glyco_hydro_6 PF01341.12 EMD68432.1 - 8.9e-84 281.4 0.4 1.1e-83 281.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF2562 PF10814.3 EMD68432.1 - 0.16 11.9 1.2 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Fungal_trans PF04082.13 EMD68433.1 - 4.1e-22 78.2 0.3 7.3e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68433.1 - 5.5e-08 32.5 7.8 1.1e-07 31.6 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_desaturase PF00487.19 EMD68435.1 - 6.1e-30 104.5 15.0 9e-30 103.9 10.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EMD68435.1 - 2.8e-19 68.0 0.6 5.1e-19 67.2 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) IKI3 PF04762.7 EMD68437.1 - 0 1104.5 0.0 0 1103.8 0.0 1.3 1 0 0 1 1 1 1 IKI3 family DUF4279 PF14106.1 EMD68437.1 - 0.049 13.5 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) COX7C PF02935.11 EMD68438.1 - 1.8e-16 59.6 0.7 2e-16 59.5 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EMD68439.1 - 1.3e-103 345.8 0.0 2.4e-103 344.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EMD68439.1 - 6.3e-64 214.5 2.5 6.3e-64 214.5 1.7 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EMD68439.1 - 1.1e-21 77.0 1.9 2.2e-21 76.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD68439.1 - 2.1e-07 30.7 0.0 5.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD68439.1 - 0.001 18.9 0.0 0.014 15.2 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EMD68439.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Cut8_C PF08559.5 EMD68440.1 - 1.8e-50 170.5 0.0 2.4e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EMD68440.1 - 1.8e-17 62.8 0.7 5.1e-17 61.3 0.5 1.8 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EMD68440.1 - 3.2e-08 33.4 2.7 5.8e-08 32.6 1.5 1.8 1 1 0 1 1 1 1 Cut8 proteasome-binding domain DUF1215 PF06744.7 EMD68440.1 - 0.045 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) DUF4184 PF13803.1 EMD68443.1 - 0.031 13.5 1.2 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) PIG-P PF08510.7 EMD68443.1 - 5 6.7 6.2 0.53 9.9 0.2 2.2 3 0 0 3 3 3 0 PIG-P DUF1253 PF06862.7 EMD68445.1 - 1.2e-155 518.2 0.1 1.5e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) JAB PF01398.16 EMD68446.1 - 8.6e-19 67.3 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMD68446.1 - 4.6e-18 65.3 0.5 6.9e-18 64.8 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EMD68446.1 - 0.023 14.1 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) IDO PF01231.13 EMD68446.1 - 0.058 11.8 0.0 0.093 11.1 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase TFIID-18kDa PF02269.11 EMD68447.1 - 1.3e-24 85.7 0.1 1.3e-24 85.7 0.1 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EMD68447.1 - 1.9e-05 24.7 0.1 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EMD68447.1 - 0.00034 20.6 0.1 0.00057 19.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EMD68447.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EMD68447.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF1242 PF06842.7 EMD68448.1 - 3.3e-16 58.4 0.2 4.2e-16 58.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) PAGK PF15284.1 EMD68448.1 - 0.093 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Phage-encoded virulence factor DUF4305 PF14146.1 EMD68448.1 - 0.6 9.9 2.9 3.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) Protoglobin PF11563.3 EMD68450.1 - 8.5e-58 194.4 0.2 1.1e-57 194.1 0.2 1.1 1 0 0 1 1 1 1 Protoglobin NmrA PF05368.8 EMD68452.1 - 6.2e-23 81.2 0.0 7.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD68452.1 - 2.6e-09 37.3 0.1 5.2e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMD68452.1 - 3.8e-05 23.2 0.3 0.00096 18.6 0.0 2.6 2 2 0 2 2 2 1 NAD dependent epimerase/dehydratase family CBS PF00571.23 EMD68452.1 - 0.0015 18.2 0.1 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 CBS domain NAD_binding_2 PF03446.10 EMD68452.1 - 0.0049 16.7 0.1 0.064 13.0 0.0 2.3 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3323 PF11796.3 EMD68452.1 - 0.015 14.5 3.0 0.22 10.8 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) RmlD_sub_bind PF04321.12 EMD68452.1 - 0.016 14.1 0.2 0.038 12.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMD68452.1 - 0.033 14.5 0.4 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain B12-binding PF02310.14 EMD68452.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain NAD_binding_4 PF07993.7 EMD68452.1 - 0.33 9.8 1.8 2.8 6.7 0.0 2.6 2 1 0 2 2 2 0 Male sterility protein CFEM PF05730.6 EMD68453.1 - 7.1e-15 54.5 9.5 1.2e-14 53.8 6.6 1.4 1 0 0 1 1 1 1 CFEM domain DUF4066 PF13278.1 EMD68455.1 - 5.7e-27 94.0 0.2 1.4e-26 92.7 0.1 1.6 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMD68455.1 - 7.2e-14 51.4 0.1 1.8e-13 50.1 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EMD68455.1 - 6.2e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I AAA_16 PF13191.1 EMD68457.1 - 3.3e-05 23.9 0.0 5.3e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMD68457.1 - 5.7e-05 23.9 0.2 0.00028 21.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD68457.1 - 7.3e-05 22.6 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD68457.1 - 0.00023 20.3 0.1 0.00077 18.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EMD68457.1 - 0.00053 19.5 0.0 0.0024 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 EMD68457.1 - 0.0062 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EMD68457.1 - 0.0079 14.9 0.0 0.016 13.9 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 EMD68457.1 - 0.0099 16.1 0.1 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMD68457.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EMD68457.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EMD68457.1 - 0.042 13.2 0.0 0.067 12.6 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EMD68457.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.15 EMD68457.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.1 EMD68457.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD68457.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Thymidylate_kin PF02223.12 EMD68457.1 - 0.084 12.2 0.2 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase Integrase_DNA PF02920.10 EMD68457.1 - 0.09 12.2 0.1 4.7 6.7 0.1 2.7 1 1 0 1 1 1 0 DNA binding domain of tn916 integrase MobB PF03205.9 EMD68457.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF463 PF04317.7 EMD68457.1 - 0.13 10.7 0.1 0.27 9.7 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 PRELI PF04707.9 EMD68459.1 - 7.7e-45 152.2 0.1 9.4e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family UPF0160 PF03690.8 EMD68460.1 - 1.9e-116 388.9 0.0 2.2e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 EMD68461.1 - 1.8e-138 461.6 9.0 2.1e-138 461.4 6.2 1.0 1 0 0 1 1 1 1 ICE2 Hexapep PF00132.19 EMD68462.1 - 1.9e-14 52.4 13.9 1.9e-10 39.7 3.6 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMD68462.1 - 5e-09 35.5 11.5 2.6e-07 30.0 2.1 3.0 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EMD68462.1 - 3.2e-08 33.3 8.8 3.2e-08 33.3 6.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.3 EMD68462.1 - 3.7e-08 33.2 0.2 1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Ribosomal_L3 PF00297.17 EMD68463.1 - 3.9e-34 118.2 7.5 1.8e-33 116.0 5.2 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Pec_lyase_C PF00544.14 EMD68465.1 - 9.7e-19 67.6 3.5 9.7e-19 67.6 2.4 1.7 2 0 0 2 2 2 1 Pectate lyase DUF3405 PF11885.3 EMD68466.1 - 1.5e-210 699.6 5.0 1.5e-210 699.6 3.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DAO PF01266.19 EMD68466.1 - 0.079 11.8 0.1 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Acyl-CoA_dh_1 PF00441.19 EMD68467.1 - 2.5e-31 108.7 5.6 4.9e-31 107.8 3.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD68467.1 - 5.3e-18 65.6 0.0 1.6e-17 64.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMD68467.1 - 1.3e-15 56.6 0.1 4e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMD68467.1 - 1.6e-14 54.2 11.6 7.2e-14 52.1 4.6 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Patatin PF01734.17 EMD68468.1 - 2.2e-22 80.0 2.4 4.1e-12 46.4 0.1 2.6 1 1 1 2 2 2 2 Patatin-like phospholipase TPR_10 PF13374.1 EMD68468.1 - 1.8e-06 27.6 6.9 5.1e-06 26.2 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD68468.1 - 2.8e-06 27.1 0.2 1.6e-05 24.7 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 EMD68468.1 - 2.1e-05 23.5 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EMD68468.1 - 4.2e-05 23.6 0.1 0.00027 20.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain PPV_E1_C PF00519.12 EMD68468.1 - 0.00023 19.8 0.4 0.00058 18.5 0.0 1.7 2 0 0 2 2 2 1 Papillomavirus helicase AAA_22 PF13401.1 EMD68468.1 - 0.01 15.9 0.0 0.045 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.1 EMD68468.1 - 0.32 11.7 5.4 7.7 7.4 0.1 4.5 3 2 2 5 5 5 0 Tetratricopeptide repeat HTH_psq PF05225.11 EMD68469.1 - 1.3e-09 37.4 0.2 2e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EMD68469.1 - 0.00095 19.0 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_7 PF02796.10 EMD68469.1 - 0.0072 16.1 0.1 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.8 EMD68469.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 EMD68469.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 EMD68469.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EMD68470.1 - 9.4e-58 195.8 0.0 1.3e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_synt PF01943.12 EMD68471.1 - 0.16 11.2 13.1 0.011 15.0 4.0 2.2 1 1 2 3 3 3 0 Polysaccharide biosynthesis protein DUF621 PF04789.10 EMD68471.1 - 3.2 6.6 16.9 0.018 14.0 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF621) p450 PF00067.17 EMD68472.1 - 1.1e-11 44.0 0.0 9e-11 40.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EMD68473.1 - 4e-82 267.4 36.3 3.3e-14 52.1 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat HET PF06985.6 EMD68473.1 - 4.7e-24 85.1 6.9 1.9e-22 79.9 4.8 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EMD68473.1 - 2.3e-21 76.1 0.0 4.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD68473.1 - 1.9e-15 56.0 24.1 0.0056 14.8 0.3 6.2 1 1 5 6 6 6 6 Nucleoporin Nup120/160 Nbas_N PF15492.1 EMD68473.1 - 0.0063 15.6 16.3 6.9 5.6 0.1 5.5 1 1 5 6 6 6 3 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 EMD68473.1 - 0.03 14.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Asp_decarbox PF02261.11 EMD68473.1 - 0.099 12.2 0.0 39 3.8 0.0 4.2 1 1 5 6 6 6 0 Aspartate decarboxylase DUF2293 PF10056.4 EMD68473.1 - 0.26 11.3 2.4 2.9 7.9 0.0 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) AATase PF07247.7 EMD68474.1 - 1.7e-21 76.3 0.0 4.3e-20 71.7 0.0 2.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMD68474.1 - 0.035 12.9 0.1 0.14 10.9 0.1 1.8 2 0 0 2 2 2 0 Condensation domain Abhydrolase_3 PF07859.8 EMD68475.1 - 7.5e-46 156.3 0.2 9.8e-46 155.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMD68475.1 - 5.1e-05 22.1 0.0 0.00014 20.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family DIT1_PvcA PF05141.7 EMD68476.1 - 7.1e-87 291.2 0.0 1.2e-86 290.5 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 EMD68476.1 - 9.6e-27 93.4 0.0 2e-26 92.3 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EMD68476.1 - 8e-13 47.8 51.0 9.7e-10 37.6 25.1 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Transferase PF02458.10 EMD68476.1 - 5.8e-10 38.1 0.0 2.2e-08 33.0 0.0 2.8 1 1 0 1 1 1 1 Transferase family PP-binding PF00550.20 EMD68476.1 - 4e-06 27.0 0.0 8.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site WD40 PF00400.27 EMD68477.1 - 3.9e-64 210.4 11.1 3.4e-13 48.9 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 EMD68477.1 - 2.5e-25 89.0 0.1 5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD68477.1 - 4.1e-23 82.0 9.7 3.4e-22 79.0 5.1 3.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Gmad1 PF10647.4 EMD68477.1 - 9.1e-07 28.5 5.8 0.00099 18.5 0.1 4.6 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EMD68477.1 - 9.1e-07 28.4 4.3 10 5.8 0.0 6.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EMD68477.1 - 1.1e-06 27.1 9.3 0.0047 15.1 1.7 4.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 RNA_helicase PF00910.17 EMD68477.1 - 0.0056 16.8 0.1 0.32 11.1 0.0 3.5 4 0 0 4 4 4 1 RNA helicase PQQ_2 PF13360.1 EMD68477.1 - 0.013 14.9 2.3 0.095 12.1 1.0 2.3 1 1 1 2 2 2 0 PQQ-like domain AAA_16 PF13191.1 EMD68477.1 - 0.016 15.2 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Asp_decarbox PF02261.11 EMD68477.1 - 0.022 14.3 0.0 1.3 8.5 0.0 3.3 3 1 1 4 4 4 0 Aspartate decarboxylase Med11 PF10280.4 EMD68477.1 - 0.023 14.7 0.0 5.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Mediator complex protein Ank_2 PF12796.2 EMD68478.1 - 1e-10 41.7 0.0 3.6e-10 40.0 0.0 1.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMD68478.1 - 3.6e-09 35.9 0.6 2.8e-05 23.9 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 EMD68478.1 - 4.8e-09 35.5 0.0 1.1e-05 24.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMD68478.1 - 4.2e-08 33.5 0.0 3e-06 27.5 0.0 3.0 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD68478.1 - 2.2e-05 24.5 0.0 0.032 14.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Hemagglutinin PF00509.13 EMD68478.1 - 0.069 11.2 0.0 0.079 11.0 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin Ank_2 PF12796.2 EMD68479.1 - 3.7e-13 49.6 0.0 4.4e-07 30.1 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMD68479.1 - 1.3e-11 44.2 0.0 0.0065 16.6 0.0 5.6 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD68479.1 - 1.1e-09 37.5 0.0 0.12 12.6 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EMD68479.1 - 6.2e-07 29.7 0.0 0.0011 19.3 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EMD68479.1 - 1.5e-06 27.6 0.0 1.4 8.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.2 EMD68479.1 - 0.054 13.2 0.5 0.13 11.9 0.4 1.7 1 0 0 1 1 1 0 F-box-like Bromodomain PF00439.20 EMD68480.1 - 7.7e-40 134.7 8.0 3.8e-20 71.5 0.2 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EMD68480.1 - 9.5e-17 60.8 0.8 2.2e-16 59.6 0.5 1.7 1 0 0 1 1 1 1 BAH domain DUF3492 PF11997.3 EMD68480.1 - 1.2 8.6 5.8 3.1 7.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) OTU PF02338.14 EMD68481.1 - 3.8e-10 40.4 0.0 6.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease AAA_10 PF12846.2 EMD68482.1 - 5.1e-10 39.2 0.0 4.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EMD68482.1 - 0.00032 20.2 0.1 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) Zeta_toxin PF06414.7 EMD68482.1 - 0.022 13.8 0.0 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EMD68482.1 - 0.029 13.8 0.4 1.2 8.5 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.24 EMD68482.1 - 0.055 13.6 0.2 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD68482.1 - 0.12 12.5 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3804 PF12707.2 EMD68482.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) BTB PF00651.26 EMD68483.1 - 0.075 13.0 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DnaJ PF00226.26 EMD68484.1 - 2.9e-25 87.7 2.3 9.5e-25 86.1 1.6 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EMD68484.1 - 1.5e-19 69.3 8.8 9e-09 34.8 0.0 5.8 3 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 EMD68484.1 - 1.4e-18 65.2 5.2 0.00044 19.9 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EMD68484.1 - 8e-17 60.0 4.6 1.3e-06 27.7 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD68484.1 - 1.5e-12 47.8 2.0 0.00045 20.8 2.4 6.1 3 2 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD68484.1 - 2.1e-12 46.5 4.1 0.39 11.4 0.0 7.2 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMD68484.1 - 2.7e-09 36.1 7.7 0.0015 18.1 0.0 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68484.1 - 1e-07 32.1 8.1 0.049 13.9 0.2 5.2 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD68484.1 - 2.2e-07 30.5 0.7 0.0034 17.4 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD68484.1 - 1.4e-06 28.1 6.7 0.023 14.6 0.2 6.1 3 3 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMD68484.1 - 1.4e-06 28.0 6.2 0.14 12.0 0.0 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMD68484.1 - 1.5e-05 25.1 13.2 1.6 9.3 0.0 6.8 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD68484.1 - 0.013 15.2 2.6 26 4.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SLS PF14611.1 EMD68484.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Fis1_TPR_C PF14853.1 EMD68484.1 - 0.077 12.8 0.7 6.5 6.7 0.0 3.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat tRNA-synt_1g PF09334.6 EMD68484.1 - 0.096 11.3 1.8 0.16 10.5 0.9 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (M) Cellulase PF00150.13 EMD68485.1 - 1.8e-12 47.0 5.5 2.2e-09 36.9 1.4 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.7 EMD68486.1 - 1e-11 44.9 2.1 1.6e-07 31.3 0.0 3.7 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 EMD68486.1 - 2.9e-06 27.0 0.0 0.00015 21.6 0.0 3.6 2 1 1 3 3 3 1 Importin-beta N-terminal domain MOR2-PAG1_N PF14222.1 EMD68486.1 - 0.0027 16.4 0.0 0.0027 16.4 0.0 2.1 3 0 0 3 3 3 1 Cell morphogenesis N-terminal IFRD PF05004.8 EMD68486.1 - 0.0032 16.5 0.6 0.2 10.7 0.0 2.7 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) DHDPS PF00701.17 EMD68487.1 - 7.8e-37 126.4 0.0 9.5e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rsa3 PF14615.1 EMD68488.1 - 1.3e-20 72.4 0.1 1.5e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TPR_16 PF13432.1 EMD68489.1 - 6.3e-09 36.2 6.3 1.7e-08 34.8 2.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMD68489.1 - 3.5e-08 33.3 4.8 0.011 16.2 0.2 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD68489.1 - 2.6e-07 29.9 3.9 0.029 14.1 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD68489.1 - 9.7e-07 28.3 11.5 0.00014 21.4 1.9 3.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMD68489.1 - 1.4e-05 24.6 6.5 0.38 10.7 0.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68489.1 - 1.9e-05 24.8 7.4 0.35 11.2 0.2 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMD68489.1 - 0.00033 20.6 0.2 0.93 9.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMD68489.1 - 0.0011 18.4 5.1 0.0021 17.5 0.6 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD68489.1 - 0.0033 17.7 1.6 0.59 10.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD68489.1 - 0.0086 15.9 4.7 1.4 8.9 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EMD68489.1 - 0.029 14.3 5.8 0.097 12.6 1.8 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMD68489.1 - 0.071 13.2 3.2 5 7.3 0.4 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMD68489.1 - 0.11 12.3 2.5 8.8 6.4 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD68490.1 - 7.2e-39 131.2 29.8 9.5e-07 28.3 0.0 10.9 10 1 1 12 12 12 7 TPR repeat TPR_1 PF00515.23 EMD68490.1 - 9.8e-36 119.9 19.6 0.00014 21.3 0.0 13.4 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_17 PF13431.1 EMD68490.1 - 1.6e-29 99.5 6.2 0.0059 16.7 0.4 13.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMD68490.1 - 1.5e-28 96.3 40.5 0.0022 17.7 0.0 14.6 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_12 PF13424.1 EMD68490.1 - 6.7e-27 93.2 32.4 0.00028 20.7 0.5 11.7 8 4 3 12 12 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EMD68490.1 - 1.3e-22 79.8 31.5 0.0036 17.9 0.1 12.5 11 1 2 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMD68490.1 - 7.6e-22 75.4 14.4 0.029 14.1 0.0 12.1 12 1 1 13 13 13 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMD68490.1 - 4e-21 73.5 20.6 0.023 15.3 0.1 12.9 10 3 4 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68490.1 - 4.1e-20 71.8 18.0 0.001 19.3 0.0 10.7 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMD68490.1 - 1.5e-08 33.7 19.6 3.1 7.8 0.0 11.6 13 1 0 13 13 13 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD68490.1 - 4.9e-07 29.7 29.0 7.4 7.2 0.0 13.1 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMD68490.1 - 1.2e-05 25.0 12.6 0.63 9.9 0.5 7.7 9 2 2 11 11 9 3 Tetratricopeptide repeat ChAPs PF09295.5 EMD68490.1 - 0.0074 15.0 0.8 14 4.2 0.0 4.7 4 1 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.7 EMD68490.1 - 0.013 15.0 2.8 18 4.8 0.0 4.3 5 0 0 5 5 4 0 Plant specific mitochondrial import receptor subunit TOM20 Apc5 PF12862.2 EMD68490.1 - 0.019 14.7 6.9 1.9 8.3 0.1 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 Tcf25 PF04910.9 EMD68490.1 - 0.028 13.3 0.4 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Fis1_TPR_C PF14853.1 EMD68490.1 - 0.47 10.3 3.2 4.9 7.1 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Glyco_hydro_17 PF00332.13 EMD68494.1 - 0.0046 16.0 0.1 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 XPG_I PF00867.13 EMD68495.1 - 3.2e-25 87.9 0.0 7.7e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMD68495.1 - 1.7e-23 82.7 0.0 3.3e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EMD68495.1 - 6e-07 29.2 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EMD68495.1 - 0.00013 22.0 0.0 0.00038 20.6 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF2962 PF11176.3 EMD68496.1 - 1.3e-45 154.7 4.4 1.4e-45 154.5 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3616 PF12275.3 EMD68496.1 - 0.016 14.1 0.3 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) DUF465 PF04325.8 EMD68496.1 - 0.064 12.9 0.1 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) ABM PF03992.11 EMD68497.1 - 0.00046 20.1 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.6 EMD68497.1 - 0.0035 17.1 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1330) Gly_transf_sug PF04488.10 EMD68498.1 - 2e-09 37.7 0.0 6.1e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMD68498.1 - 1.4e-05 23.7 0.0 0.0042 15.6 0.0 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EMD68498.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein WD40 PF00400.27 EMD68499.1 - 0.0059 16.4 0.8 0.047 13.6 0.5 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat CorA PF01544.13 EMD68499.1 - 0.64 9.0 1.7 1.1 8.1 1.2 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Proteasome PF00227.21 EMD68500.1 - 1.3e-44 151.7 0.0 1.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EMD68500.1 - 9e-14 50.4 1.9 2.4e-13 49.0 1.3 1.8 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Actin PF00022.14 EMD68501.1 - 3.6e-132 440.5 0.0 4.1e-132 440.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMD68501.1 - 0.17 10.4 0.0 13 4.3 0.0 2.4 3 0 0 3 3 3 0 MreB/Mbl protein MBOAT PF03062.14 EMD68502.1 - 2.8e-44 151.5 17.3 5.2e-44 150.6 12.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Glyco_hydro_17 PF00332.13 EMD68503.1 - 6.9e-05 22.0 0.1 6.9e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF605 PF04652.11 EMD68503.1 - 7.1 5.9 17.0 10 5.3 11.8 1.1 1 0 0 1 1 1 0 Vta1 like Pyridoxal_deC PF00282.14 EMD68504.1 - 7.2e-79 264.9 0.0 1.8e-78 263.6 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMD68504.1 - 1.3e-08 34.3 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMD68504.1 - 0.004 15.9 0.0 0.0076 15.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V PUF PF00806.14 EMD68505.1 - 1.5e-11 43.0 0.0 0.35 10.4 0.0 7.0 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat RINT1_TIP1 PF04437.8 EMD68506.1 - 3.8e-140 467.7 0.0 6.2e-140 467.0 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Baculo_PEP_C PF04513.7 EMD68506.1 - 0.026 14.3 6.6 11 5.8 0.0 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med2 PF11214.3 EMD68506.1 - 0.028 14.4 2.5 1.1 9.2 0.5 3.4 2 1 0 2 2 2 0 Mediator complex subunit 2 MT0933_antitox PF14013.1 EMD68507.1 - 0.72 10.0 6.6 2.2 8.4 1.2 2.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein MT0933_antitox PF14013.1 EMD68508.1 - 0.0017 18.4 3.7 0.26 11.4 0.2 2.1 1 1 1 2 2 2 2 MT0933-like antitoxin protein Y_phosphatase3C PF13348.1 EMD68508.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Folliculin PF11704.3 EMD68509.1 - 4e-37 127.3 0.0 1.2e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport F-box PF00646.28 EMD68510.1 - 0.049 13.2 0.2 0.049 13.2 0.2 2.1 2 0 0 2 2 2 0 F-box domain DUF1880 PF08976.6 EMD68510.1 - 0.23 11.6 1.4 0.5 10.4 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) COesterase PF00135.23 EMD68511.1 - 9.8e-82 275.3 0.0 1.1e-81 275.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD68511.1 - 1.7e-07 30.9 0.2 3.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold LEA_4 PF02987.11 EMD68512.1 - 0.0014 18.4 20.3 0.012 15.4 6.1 2.4 2 1 1 3 3 3 2 Late embryogenesis abundant protein DUF883 PF05957.8 EMD68512.1 - 0.016 15.5 2.7 0.03 14.7 1.7 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 EMD68512.1 - 0.32 11.0 3.5 0.46 10.5 2.5 1.4 1 1 0 1 1 1 0 DivIVA protein ISG65-75 PF11727.3 EMD68512.1 - 0.35 9.8 6.4 0.48 9.4 4.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein CsbD PF05532.7 EMD68512.1 - 1.1 8.9 19.6 0.2 11.3 3.5 2.9 2 1 1 3 3 3 0 CsbD-like ATP-synt_B PF00430.13 EMD68512.1 - 4.3 7.1 7.1 3.5 7.4 2.9 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Baculo_helicase PF04735.7 EMD68514.1 - 0.054 10.8 0.1 0.074 10.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase Acetyltransf_13 PF13880.1 EMD68519.1 - 1.4e-25 88.8 0.0 3.3e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EMD68519.1 - 2.6e-15 55.6 0.3 5.3e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EMD68519.1 - 0.035 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD68519.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD68520.1 - 4.7e-27 94.8 0.0 5.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMD68520.1 - 4.5e-06 26.7 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD68520.1 - 7.7e-06 25.8 0.2 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CLP_protease PF00574.18 EMD68522.1 - 2.2e-76 255.5 0.0 2.7e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.1 EMD68522.1 - 0.0036 17.1 2.6 0.0053 16.6 0.6 2.0 2 0 0 2 2 2 1 Clr5 domain Peptidase_S49 PF01343.13 EMD68522.1 - 0.058 13.1 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 RdRP PF05183.7 EMD68523.1 - 3.4e-168 560.9 0.0 4.6e-168 560.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ank PF00023.25 EMD68524.1 - 3.8e-12 45.3 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMD68524.1 - 4.8e-12 46.0 0.0 6.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD68524.1 - 1.1e-11 44.8 0.1 1.9e-07 31.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD68524.1 - 1.7e-08 34.4 0.6 0.00033 20.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD68524.1 - 0.00064 19.7 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat ATG22 PF11700.3 EMD68526.1 - 0.21 10.0 3.8 1.5 7.2 0.8 2.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Cellulase PF00150.13 EMD68528.1 - 4.2e-24 85.2 0.2 5.8e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CUE PF02845.11 EMD68532.1 - 4.2e-11 42.0 0.1 1.1e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 CUE domain Ribosomal_S10 PF00338.17 EMD68533.1 - 4e-30 103.5 0.8 4.8e-30 103.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e COG5 PF10392.4 EMD68534.1 - 0.019 14.9 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 D-ser_dehydrat PF14031.1 EMD68536.1 - 2e-22 79.1 0.0 4.2e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EMD68536.1 - 4.2e-13 49.3 0.0 6.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PKD_channel PF08016.7 EMD68537.1 - 0.0078 14.6 5.9 0.4 9.0 0.7 2.3 2 0 0 2 2 2 2 Polycystin cation channel DnaJ PF00226.26 EMD68538.1 - 5e-11 42.1 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_2 PF13923.1 EMD68538.1 - 2.1 8.4 11.5 4.2 7.4 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF791 PF05631.9 EMD68539.1 - 5.1e-61 206.3 3.6 7.8e-61 205.7 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EMD68539.1 - 1.2e-25 89.9 20.6 1.8e-25 89.4 14.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMD68539.1 - 0.068 11.5 17.0 0.019 13.3 5.3 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein Methyltransf_22 PF13383.1 EMD68540.1 - 2.2e-18 66.6 0.0 3.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EMD68540.1 - 5.2e-06 26.5 0.0 7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain 2_5_RNA_ligase2 PF13563.1 EMD68541.1 - 2.5e-26 92.2 0.3 1.1e-25 90.1 0.0 2.2 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EMD68541.1 - 2.6e-23 82.1 0.0 6.1e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EMD68541.1 - 1.7e-15 57.6 0.1 4.6e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EMD68541.1 - 4.1e-09 36.4 0.3 1.6e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF504) Nrap PF03813.9 EMD68541.1 - 7.6e-06 23.7 0.1 1.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Nrap protein NTP_transf_2 PF01909.18 EMD68541.1 - 0.00016 21.9 0.0 0.0006 20.0 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EMD68541.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase Exo_endo_phos_2 PF14529.1 EMD68541.1 - 0.026 14.1 2.3 0.084 12.4 0.2 2.8 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase TPR_6 PF13174.1 EMD68541.1 - 0.08 13.4 0.3 1 9.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Transferase PF02458.10 EMD68542.1 - 0.032 12.6 0.0 0.72 8.2 0.0 2.1 2 0 0 2 2 2 0 Transferase family Condensation PF00668.15 EMD68542.1 - 0.07 11.9 0.3 0.12 11.1 0.2 1.3 1 0 0 1 1 1 0 Condensation domain DUF1282 PF06930.7 EMD68543.1 - 0.0032 17.1 2.2 0.0042 16.7 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF3357 PF11837.3 EMD68543.1 - 0.64 9.9 2.2 0.83 9.5 0.1 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) Cortexin PF11057.3 EMD68543.1 - 0.85 9.2 0.0 0.85 9.2 0.0 2.5 2 1 1 3 3 3 0 Cortexin of kidney Peptidase_C14 PF00656.17 EMD68545.1 - 0.0087 15.7 0.1 0.058 13.0 0.0 1.9 1 1 1 2 2 2 1 Caspase domain MFS_1 PF07690.11 EMD68546.1 - 1.7e-43 148.6 40.5 1.7e-43 148.6 28.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68546.1 - 5.4e-07 28.5 39.9 3.5e-06 25.8 28.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3671 PF12420.3 EMD68546.1 - 2.5 8.1 6.1 18 5.3 2.3 3.0 2 1 0 2 2 2 0 Protein of unknown function Herpes_LMP1 PF05297.6 EMD68546.1 - 2.7 6.8 6.1 5.9 5.7 4.2 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PNP_UDP_1 PF01048.15 EMD68547.1 - 3.4e-13 49.1 1.3 1e-12 47.5 0.9 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Peptidase_S28 PF05577.7 EMD68548.1 - 4.4e-22 78.2 0.0 6.3e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF4185 PF13810.1 EMD68548.1 - 0.0048 15.8 0.1 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) PNP_UDP_1 PF01048.15 EMD68549.1 - 1.2e-07 30.9 2.8 1.5e-06 27.4 1.9 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 EMD68550.1 - 2.4e-48 160.3 21.2 2.4e-12 46.2 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat NACHT PF05729.7 EMD68550.1 - 1.8e-06 27.6 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EMD68550.1 - 8.2e-05 20.9 14.9 0.77 7.8 0.0 5.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Asp_decarbox PF02261.11 EMD68550.1 - 0.0001 21.8 0.0 11 5.6 0.0 4.7 2 2 2 4 4 4 1 Aspartate decarboxylase AAA_16 PF13191.1 EMD68550.1 - 0.00083 19.3 0.2 0.0026 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD68550.1 - 0.0042 17.2 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EMD68550.1 - 0.0094 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_19 PF13245.1 EMD68550.1 - 0.03 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EMD68550.1 - 0.031 15.0 0.1 0.23 12.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain CDtoxinA PF03498.9 EMD68550.1 - 0.042 13.2 2.7 1.4 8.2 0.4 3.6 1 1 2 4 4 4 0 Cytolethal distending toxin A/C family AAA_33 PF13671.1 EMD68550.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMD68550.1 - 0.1 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMD68550.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.16 EMD68551.1 - 1.3e-21 77.1 0.0 1.9e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD68551.1 - 4.8e-12 45.1 0.0 3.3e-10 39.1 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD68551.1 - 7.3e-12 45.6 0.0 4.8e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMD68551.1 - 2.8e-08 33.2 0.0 4.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMD68551.1 - 3.9e-06 26.8 0.1 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMD68551.1 - 7.1e-06 25.1 0.0 0.0042 16.0 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 EMD68551.1 - 0.00039 19.4 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMD68551.1 - 0.0084 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMD68552.1 - 2.3e-32 112.1 0.0 2.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD68552.1 - 2.4e-06 27.7 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMD68552.1 - 0.0052 15.5 0.0 0.0085 14.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMD68552.1 - 0.022 14.1 0.0 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EMD68552.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.2 EMD68554.1 - 6e-22 77.7 0.1 7.5e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD68554.1 - 1.5e-18 65.5 0.2 3.9e-08 32.7 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EMD68554.1 - 1.8e-14 52.3 0.5 0.00033 20.6 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMD68554.1 - 3.5e-12 46.4 0.1 1.1e-06 28.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD68554.1 - 4.8e-12 45.7 0.3 0.00014 22.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1987 PF09345.5 EMD68555.1 - 0.043 13.6 0.2 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) HET PF06985.6 EMD68557.1 - 2e-22 79.8 0.0 2.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EMD68558.1 - 2.7e-10 39.3 0.0 2.8e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EMD68559.1 - 2.8e-34 118.2 3.2 4.7e-34 117.5 2.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIR_2 PF13676.1 EMD68559.1 - 0.013 15.5 0.2 0.043 13.9 0.1 1.9 1 0 0 1 1 1 0 TIR domain Yip1 PF04893.12 EMD68560.1 - 0.0031 17.0 3.1 0.0046 16.4 2.2 1.2 1 0 0 1 1 1 1 Yip1 domain Amastin PF07344.6 EMD68560.1 - 0.01 15.4 4.0 0.01 15.4 2.8 1.4 2 0 0 2 2 2 0 Amastin surface glycoprotein Tetraspannin PF00335.15 EMD68560.1 - 0.17 11.1 6.5 0.25 10.5 4.5 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4231 PF14015.1 EMD68560.1 - 0.31 11.0 3.2 0.7 9.9 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DSBA PF01323.15 EMD68561.1 - 2.9e-11 43.2 0.0 3.3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GST_C PF00043.20 EMD68562.1 - 6e-14 51.8 0.0 8.6e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMD68562.1 - 4.3e-12 46.0 0.0 8.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMD68562.1 - 3.6e-11 43.1 0.0 6.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD68562.1 - 5.3e-10 39.0 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMD68562.1 - 1.2e-08 34.7 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMD68562.1 - 1.7e-06 28.4 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 EMD68563.1 - 2.2e-14 52.9 0.0 3.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.11 EMD68564.1 - 0.0063 16.2 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Cu_amine_oxid PF01179.15 EMD68565.1 - 9e-170 564.8 0.0 1.6e-169 564.0 0.0 1.4 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EMD68565.1 - 9.3e-19 67.3 0.1 4.7e-18 65.1 0.0 2.1 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMD68565.1 - 2e-13 50.1 0.0 3.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.17 EMD68566.1 - 1.1e-154 515.2 0.0 1.2e-154 515.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cupin_2 PF07883.6 EMD68567.1 - 1.4e-05 24.5 0.4 1.9e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMD68567.1 - 0.0001 21.5 0.2 0.00015 21.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EMD68567.1 - 0.057 13.0 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Cupin EutQ PF06249.7 EMD68567.1 - 0.057 12.9 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 EMD68567.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Amino_oxidase PF01593.19 EMD68568.1 - 3.7e-41 141.6 0.9 1.5e-40 139.6 0.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD68568.1 - 8e-11 41.8 0.1 1.9e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD68568.1 - 8e-08 31.5 0.0 1.1e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMD68568.1 - 1.9e-07 30.4 0.0 3.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMD68568.1 - 1.6e-06 27.3 0.2 5.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMD68568.1 - 2.9e-05 24.0 0.1 0.0001 22.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD68568.1 - 5.2e-05 22.2 0.0 8.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMD68568.1 - 0.00028 20.0 0.2 0.0012 18.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMD68568.1 - 0.0016 16.9 0.1 0.0031 16.0 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EMD68568.1 - 0.0026 17.5 0.1 0.085 12.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD68568.1 - 0.0028 17.7 0.0 0.0089 16.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD68568.1 - 0.019 15.3 0.2 0.047 14.1 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DSRB PF10781.4 EMD68568.1 - 0.12 11.8 0.4 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Dextransucrase DSRB AA_permease_2 PF13520.1 EMD68569.1 - 1.5e-42 145.6 47.9 1.9e-42 145.2 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD68569.1 - 7.7e-16 57.4 41.6 1e-15 57.0 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_N PF02776.13 EMD68570.1 - 1.1e-37 129.1 0.7 2.4e-37 128.0 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD68570.1 - 2e-18 66.4 0.0 1.3e-17 63.8 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD68570.1 - 3.4e-18 65.6 0.5 7.6e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NTP_transf_3 PF12804.2 EMD68570.1 - 0.064 13.3 0.6 0.73 9.8 0.1 2.7 2 1 0 2 2 2 0 MobA-like NTP transferase domain Fungal_trans_2 PF11951.3 EMD68571.1 - 2.8e-31 108.4 7.3 9.8e-31 106.6 5.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD-oxidase_C PF02913.14 EMD68572.1 - 1.4e-64 217.8 0.4 2.3e-64 217.0 0.1 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMD68572.1 - 5.1e-34 116.7 0.0 1.1e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain LysM PF01476.15 EMD68574.1 - 6.2e-23 80.4 7.0 1e-06 28.5 0.0 6.4 6 0 0 6 6 6 6 LysM domain Glyco_hydro_18 PF00704.23 EMD68575.1 - 3.6e-79 266.6 0.9 5.5e-79 266.1 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMD68575.1 - 2.2e-09 37.1 10.6 2.2e-09 37.1 7.4 4.1 4 0 0 4 4 4 2 Chitin recognition protein NdhN PF11909.3 EMD68575.1 - 0.35 10.1 0.0 0.68 9.2 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N DPBB_1 PF03330.13 EMD68576.1 - 6e-05 22.9 2.2 8.3e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EMD68576.1 - 0.0052 16.5 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Pollen allergen UNC-50 PF05216.8 EMD68577.1 - 5.1e-80 268.0 13.7 6.1e-80 267.7 9.5 1.0 1 0 0 1 1 1 1 UNC-50 family Suf PF05843.9 EMD68578.1 - 2.3e-84 283.4 16.1 2.5e-82 276.7 0.0 4.9 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EMD68578.1 - 1.4e-05 25.5 0.0 0.099 13.3 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68578.1 - 0.0011 19.2 0.0 0.013 15.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.11 EMD68578.1 - 0.089 12.5 11.6 0.085 12.6 0.7 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EMD68578.1 - 0.14 12.8 11.0 0.16 12.6 0.0 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat Piwi PF02171.12 EMD68579.1 - 3.8e-73 246.0 0.0 5.3e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMD68579.1 - 1.1e-19 69.4 0.3 2.7e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EMD68579.1 - 3.4e-14 52.2 0.1 5.9e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 PAZ domain PP28 PF10252.4 EMD68580.1 - 4.2e-28 97.1 20.6 4.2e-28 97.1 14.3 3.3 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 HNH PF01844.18 EMD68581.1 - 0.0011 18.8 1.1 0.0025 17.6 0.8 1.7 1 0 0 1 1 1 1 HNH endonuclease E2_bind PF08825.5 EMD68581.1 - 0.096 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 E2 binding domain Dopey_N PF04118.9 EMD68583.1 - 1.9e-114 381.6 0.1 1.6e-112 375.3 0.0 3.5 4 1 0 4 4 4 1 Dopey, N-terminal DUF202 PF02656.10 EMD68584.1 - 0.033 14.4 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ER-remodelling PF14755.1 EMD68585.1 - 1.3 9.0 13.6 15 5.6 9.4 2.0 1 1 0 1 1 1 0 Intracellular membrane remodeller DUF3796 PF12676.2 EMD68586.1 - 0.054 13.7 2.8 0.065 13.4 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) PRA1 PF03208.14 EMD68586.1 - 2.6 7.3 7.8 3.2 7.0 5.4 1.1 1 0 0 1 1 1 0 PRA1 family protein zf-C2H2_4 PF13894.1 EMD68587.1 - 1e-05 25.4 11.4 0.11 12.8 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD68587.1 - 0.0053 17.0 15.7 0.064 13.6 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type DAO PF01266.19 EMD68589.1 - 2.4e-42 145.1 0.0 3.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD68589.1 - 3.5e-07 29.4 0.2 7.5e-07 28.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EMD68589.1 - 2.6e-05 24.0 0.0 6.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.9 EMD68589.1 - 0.00051 19.9 0.2 0.01 15.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD68589.1 - 0.0011 17.8 0.1 0.74 8.6 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EMD68589.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 EMD68589.1 - 0.0021 17.2 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMD68589.1 - 0.006 16.3 0.3 0.041 13.5 0.2 2.2 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EMD68589.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.11 EMD68589.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EMD68589.1 - 0.014 15.5 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMD68589.1 - 0.039 14.3 0.1 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD68589.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RrnaAD PF00398.15 EMD68590.1 - 1.6e-09 37.2 0.0 1.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase APH PF01636.18 EMD68591.1 - 8.3e-10 38.7 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family UBX PF00789.15 EMD68591.1 - 0.064 13.3 0.0 0.27 11.3 0.0 2.0 1 1 0 1 1 1 0 UBX domain THUMP PF02926.12 EMD68592.1 - 3.4e-13 49.7 0.0 5.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 THUMP domain SR-25 PF10500.4 EMD68593.1 - 1.8 7.9 31.8 3.7 6.9 0.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-rbx1 PF12678.2 EMD68594.1 - 6e-11 42.2 1.0 1.1e-10 41.4 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMD68594.1 - 4.2e-10 39.2 7.3 1.6e-09 37.4 5.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD68594.1 - 1.7e-07 30.8 4.4 5.1e-06 26.0 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD68594.1 - 8e-07 28.6 0.3 1.7e-06 27.6 0.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMD68594.1 - 1.4e-06 27.8 1.7 3.1e-06 26.7 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD68594.1 - 1.1e-05 25.2 2.0 1.1e-05 25.2 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMD68594.1 - 0.00014 21.4 1.8 0.00049 19.7 1.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMD68594.1 - 0.011 15.5 0.9 0.028 14.2 0.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMD68594.1 - 0.086 12.6 3.2 0.21 11.4 2.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMD68594.1 - 1.2 8.8 4.8 0.36 10.4 0.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_32N PF00251.15 EMD68595.1 - 5e-45 154.1 7.8 2.8e-44 151.7 5.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMD68595.1 - 4.4e-09 36.5 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Thioredoxin PF00085.15 EMD68597.1 - 9.6e-64 211.5 5.0 7.4e-32 109.1 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EMD68597.1 - 2.1e-54 184.0 2.0 7.8e-38 130.1 0.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMD68597.1 - 2.3e-11 43.5 0.3 0.00045 20.1 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD68597.1 - 5.2e-10 39.5 8.1 6.8e-05 23.0 0.1 4.7 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMD68597.1 - 5.3e-10 39.2 0.1 0.0018 18.3 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EMD68597.1 - 6.3e-10 38.3 1.9 1.4e-09 37.2 0.5 2.0 2 0 0 2 2 2 1 Calsequestrin Redoxin PF08534.5 EMD68597.1 - 9.3e-07 28.4 3.0 0.0091 15.5 0.0 3.6 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 EMD68597.1 - 2.8e-06 27.0 0.8 0.026 14.2 0.1 3.2 4 0 0 4 4 4 2 AhpC/TSA family ERp29_N PF07912.8 EMD68597.1 - 4.3e-05 23.4 0.4 0.27 11.1 0.0 4.1 3 2 0 3 3 3 2 ERp29, N-terminal domain DUF883 PF05957.8 EMD68597.1 - 0.22 11.9 13.4 0.51 10.7 9.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 EMD68597.1 - 0.3 11.5 15.4 0.58 10.6 10.7 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Pyridox_oxidase PF01243.15 EMD68598.1 - 1.4e-05 25.0 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CH PF00307.26 EMD68598.1 - 6.5e-05 22.9 0.0 0.0013 18.7 0.0 2.8 2 1 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EMD68598.1 - 0.00029 20.2 16.3 0.0014 18.1 0.9 3.8 3 0 0 3 3 3 2 IQ calmodulin-binding motif DsrH PF04077.7 EMD68599.1 - 0.018 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein RPN7 PF10602.4 EMD68599.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 CobT PF06213.7 EMD68599.1 - 0.13 11.4 14.8 0.18 10.9 10.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.6 EMD68599.1 - 0.85 9.1 17.9 1.3 8.5 12.4 1.2 1 0 0 1 1 1 0 PPP4R2 Ycf1 PF05758.7 EMD68599.1 - 0.96 7.0 6.7 1.2 6.7 4.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EMD68599.1 - 5 6.4 21.6 7.1 5.9 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mon1 PF03164.9 EMD68600.1 - 3.6e-86 289.3 0.0 4.8e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Epimerase PF01370.16 EMD68601.1 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD68601.1 - 5.4e-05 23.2 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD68601.1 - 0.0004 19.3 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMD68601.1 - 0.14 11.0 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2697 PF10906.3 EMD68602.1 - 3e-05 23.9 0.1 5.6e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) TonB_2 PF13103.1 EMD68602.1 - 0.096 12.7 0.0 0.65 10.0 0.0 1.9 2 0 0 2 2 2 0 TonB C terminal Y_phosphatase PF00102.22 EMD68603.1 - 1.2e-56 191.7 0.0 1.5e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMD68603.1 - 0.0018 17.8 0.1 0.0063 16.1 0.0 2.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMD68603.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Zn_clus PF00172.13 EMD68605.1 - 5.6e-09 35.7 13.4 8.7e-09 35.1 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EMD68606.1 - 5.9e-59 199.6 0.1 7.4e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase JAB PF01398.16 EMD68607.1 - 1.2e-15 57.2 0.1 4.7e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EMD68607.1 - 4.1e-07 29.9 0.9 8.2e-07 28.9 0.6 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EMD68607.1 - 2.8e-05 23.6 0.0 7.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2396 PF09654.5 EMD68607.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Pkr1 PF08636.5 EMD68608.1 - 7.2e-36 122.0 5.7 9.6e-36 121.6 4.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Trypan_PARP PF05887.6 EMD68608.1 - 0.0016 18.2 1.2 0.0025 17.6 0.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FHIPEP PF00771.15 EMD68608.1 - 0.007 14.7 0.0 0.0088 14.4 0.0 1.0 1 0 0 1 1 1 1 FHIPEP family Mem_trans PF03547.13 EMD68608.1 - 0.054 11.7 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Totivirus_coat PF05518.6 EMD68608.1 - 1.3 6.7 5.3 1.7 6.3 3.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein PPR_3 PF13812.1 EMD68610.1 - 0.11 12.8 0.2 67 4.1 0.0 4.3 5 0 0 5 5 5 0 Pentatricopeptide repeat domain 2-oxoacid_dh PF00198.18 EMD68612.1 - 9.3e-79 263.9 0.1 1.3e-78 263.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMD68612.1 - 1.8e-19 69.1 3.5 3.5e-19 68.2 2.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMD68612.1 - 0.00053 19.5 1.1 0.086 12.5 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 EMD68612.1 - 0.0021 17.2 7.9 0.0059 15.8 3.6 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EMD68612.1 - 0.011 16.1 0.6 0.95 9.8 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF605 PF04652.11 EMD68612.1 - 0.013 14.9 14.9 0.016 14.5 10.3 1.1 1 0 0 1 1 1 0 Vta1 like Tape_meas_lam_C PF09718.5 EMD68612.1 - 0.027 14.3 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RnfC_N PF13375.1 EMD68612.1 - 0.062 13.0 0.4 3.4 7.4 0.0 2.8 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GAGA_bind PF06217.7 EMD68612.1 - 1.8 8.4 9.0 2.9 7.7 6.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.1 EMD68612.1 - 3.8 7.6 5.9 8.8 6.4 4.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.2 EMD68612.1 - 9.3 3.7 10.0 12 3.4 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sugar_tr PF00083.19 EMD68613.1 - 8.3e-81 271.8 30.0 1.2e-80 271.3 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68613.1 - 2.8e-18 65.7 43.7 8.5e-15 54.3 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.7 EMD68614.1 - 3.5e-46 157.5 0.0 4.4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EMD68614.1 - 5.7e-10 38.6 0.0 0.085 12.8 0.0 5.8 6 0 0 6 6 6 2 NHL repeat Str_synth PF03088.11 EMD68614.1 - 7.2e-07 29.1 0.0 0.00028 20.8 0.0 3.2 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EMD68614.1 - 1.4e-06 28.1 0.0 0.0014 18.5 0.0 3.5 3 1 0 3 3 3 1 Arylesterase Lactonase PF10282.4 EMD68614.1 - 0.00057 19.0 0.0 0.0031 16.6 0.0 2.0 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Ldl_recept_b PF00058.12 EMD68614.1 - 0.2 12.0 0.6 61 4.0 0.0 4.0 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B Lgl_C PF08596.5 EMD68615.1 - 2.3e-119 398.3 0.0 5.6e-119 397.1 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EMD68615.1 - 8.5e-09 34.9 0.0 0.00043 20.0 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CCDC155 PF14662.1 EMD68616.1 - 4.3e-05 23.1 17.7 4.3e-05 23.1 12.3 1.7 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 DUF2353 PF09789.4 EMD68616.1 - 5.6e-05 22.5 5.9 7.6e-05 22.1 4.1 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Shugoshin_N PF07558.6 EMD68616.1 - 0.00011 21.8 1.7 0.00011 21.8 1.2 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region ERM PF00769.14 EMD68616.1 - 0.003 17.1 13.4 0.003 17.1 9.3 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF972 PF06156.8 EMD68616.1 - 0.0053 17.0 18.6 0.0089 16.3 2.0 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF972) HALZ PF02183.13 EMD68616.1 - 0.09 12.5 12.6 3.6 7.3 0.1 4.4 3 1 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EMD68616.1 - 0.16 11.9 16.3 0.11 12.4 0.7 4.5 2 1 3 5 5 5 0 bZIP transcription factor V_ATPase_I PF01496.14 EMD68616.1 - 0.23 9.2 7.5 0.3 8.8 5.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMD68616.1 - 0.24 10.9 16.6 0.31 10.5 10.3 2.0 1 1 1 2 2 2 0 IncA protein NYD-SP28_assoc PF14775.1 EMD68616.1 - 0.28 10.8 4.5 0.39 10.4 0.8 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain Phlebovirus_NSM PF07246.6 EMD68616.1 - 0.34 10.0 12.2 0.21 10.6 5.0 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF2205 PF10224.4 EMD68616.1 - 0.46 10.0 17.8 0.16 11.5 2.7 3.9 2 1 2 4 4 4 0 Predicted coiled-coil protein (DUF2205) Cep57_CLD_2 PF14197.1 EMD68616.1 - 0.6 10.0 15.5 1.1 9.2 1.8 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Kinesin-relat_1 PF12711.2 EMD68616.1 - 1.3 9.4 10.1 9.7 6.6 0.2 3.3 1 1 2 3 3 3 0 Kinesin motor GAS PF13851.1 EMD68616.1 - 2.7 7.1 20.4 1.3 8.1 11.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EMD68616.1 - 4.1 6.9 19.7 1.1 8.7 4.0 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EMD68616.1 - 4.9 6.0 20.1 23 3.9 12.5 2.2 1 1 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EMD68616.1 - 7.6 6.4 35.9 0.043 13.7 4.7 2.8 3 1 1 4 4 3 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 EMD68616.1 - 8.3 6.3 19.1 0.42 10.4 0.3 4.7 3 2 2 5 5 5 0 Basic region leucine zipper RNA_polI_A34 PF08208.6 EMD68617.1 - 1.9e-34 119.0 7.8 1.9e-34 119.0 5.4 3.2 3 0 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 AAA_22 PF13401.1 EMD68618.1 - 0.00061 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD68618.1 - 0.00083 19.3 0.4 0.0041 17.1 0.0 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EMD68618.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMD68618.1 - 0.0065 17.2 0.0 0.017 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMD68618.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EMD68618.1 - 0.027 14.3 0.2 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD68618.1 - 0.054 13.0 0.2 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EMD68618.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMD68618.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EMD68618.1 - 0.086 12.2 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EMD68618.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Complex1_LYR PF05347.10 EMD68619.1 - 4e-09 36.1 1.4 5.8e-09 35.6 1.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD68619.1 - 3.2e-07 30.4 1.0 4.3e-07 30.0 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EMD68620.1 - 8.5e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMD68620.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD68621.1 - 2.3e-22 78.8 0.2 3.2e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMD68621.1 - 5.6e-05 23.1 1.0 0.0001 22.2 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMD68621.1 - 0.00022 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EMD68621.1 - 0.022 15.2 0.2 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EMD68621.1 - 0.026 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.14 EMD68622.1 - 4.4e-94 314.7 0.0 9.9e-94 313.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C54 R3H PF01424.17 EMD68623.1 - 9.3e-14 50.8 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EMD68623.1 - 3.7e-10 39.4 0.4 3.1e-09 36.4 0.2 2.5 2 0 0 2 2 2 1 G-patch domain Chromo PF00385.19 EMD68623.1 - 8.8e-05 22.1 0.1 0.00037 20.1 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3449 PF11931.3 EMD68623.1 - 0.16 11.4 1.7 0.37 10.2 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Nucleoplasmin PF03066.10 EMD68623.1 - 0.19 11.2 12.8 0.57 9.6 8.9 1.9 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 EMD68623.1 - 0.78 8.6 11.1 1.8 7.4 7.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-MYND PF01753.13 EMD68624.1 - 1.5e-08 34.3 13.4 3e-08 33.3 9.3 1.5 1 0 0 1 1 1 1 MYND finger DUF4259 PF14078.1 EMD68624.1 - 0.0025 18.3 0.1 0.0043 17.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) MRF_C1 PF13887.1 EMD68624.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 zf-HIT PF04438.11 EMD68624.1 - 0.038 13.6 9.8 0.15 11.7 6.8 2.0 1 1 0 1 1 1 0 HIT zinc finger DUF2985 PF11204.3 EMD68625.1 - 1.1e-28 98.8 4.0 2.2e-28 97.8 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) HTH_Tnp_Tc5 PF03221.11 EMD68627.1 - 1.1e-11 44.3 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD68627.1 - 2.6e-06 26.8 0.2 4.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD68627.1 - 0.0013 18.8 0.3 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMD68627.1 - 0.034 14.1 0.1 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD68627.1 - 0.05 13.2 0.6 0.28 10.8 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Ribosomal_S13_N PF08069.7 EMD68627.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain HTH_Tnp_1 PF01527.15 EMD68627.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Transposase Cdc6_C PF09079.6 EMD68627.1 - 0.12 12.1 0.0 5.7 6.7 0.0 2.2 1 1 1 2 2 2 0 CDC6, C terminal HTH_36 PF13730.1 EMD68627.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 2 1 1 3 3 3 0 Helix-turn-helix domain Rtf2 PF04641.7 EMD68628.1 - 2.7 7.1 8.3 3.1 6.9 5.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CP2 PF04516.10 EMD68631.1 - 1.5e-88 295.8 0.0 2.4e-88 295.1 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 EMD68631.1 - 0.064 11.7 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Tektin family CENP-K PF11802.3 EMD68633.1 - 0.00016 21.0 3.7 0.047 12.9 0.0 2.3 2 1 0 2 2 2 1 Centromere-associated protein K 4HB_MCP_1 PF12729.2 EMD68633.1 - 0.14 11.5 4.4 1.1 8.5 0.2 2.6 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction Mod_r PF07200.8 EMD68633.1 - 0.15 11.9 15.1 0.16 11.8 3.7 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 EMD68633.1 - 0.27 10.8 14.6 0.61 9.7 3.0 2.3 2 0 0 2 2 2 0 Mnd1 family Bestrophin PF01062.16 EMD68633.1 - 0.48 9.3 5.2 0.67 8.8 3.2 1.5 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel TipAS PF07739.8 EMD68633.1 - 2.1 8.6 12.5 0.066 13.5 2.5 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain OmpH PF03938.9 EMD68633.1 - 3.6 7.5 26.0 0.65 9.9 7.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EMD68633.1 - 3.6 7.1 25.1 7.9 6.0 6.2 2.3 1 1 1 2 2 2 0 IncA protein KH_1 PF00013.24 EMD68634.1 - 1.1e-38 130.6 5.8 2.1e-16 59.3 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMD68634.1 - 1.1e-29 101.5 11.2 2.2e-12 46.3 1.4 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMD68634.1 - 8.6e-12 44.4 3.0 0.0043 16.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMD68634.1 - 0.0003 20.5 3.9 0.63 9.8 0.1 3.7 3 1 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 EMD68634.1 - 0.0042 16.6 3.2 5.1 6.8 0.1 3.7 4 0 0 4 4 4 2 KH domain Baculo_PEP_C PF04513.7 EMD68635.1 - 0.47 10.2 6.2 8.3 6.2 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus 4HBT_2 PF13279.1 EMD68637.1 - 9.7e-29 100.2 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EMD68637.1 - 0.033 14.2 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Methyltransf_11 PF08241.7 EMD68638.1 - 3.5e-11 43.4 0.0 6.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMD68638.1 - 1e-09 38.6 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD68638.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD68638.1 - 2.6e-07 30.4 0.0 1.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD68638.1 - 8.1e-07 29.0 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD68638.1 - 3.3e-06 27.6 0.0 1.1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD68638.1 - 3.6e-06 27.3 0.0 7.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD68638.1 - 3.8e-06 26.1 0.0 6.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EMD68638.1 - 0.0032 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EMD68638.1 - 0.04 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMD68638.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Exo_endo_phos PF03372.18 EMD68639.1 - 1.5e-19 70.9 0.3 2.8e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMD68639.1 - 1.2e-12 47.1 13.5 1.5e-06 27.6 0.6 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD68639.1 - 1.6e-08 34.1 20.7 7.8e-07 28.7 5.9 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EMD68639.1 - 2.9e-05 23.5 10.0 0.052 13.5 0.4 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat DUF3921 PF13060.1 EMD68639.1 - 0.022 14.6 0.1 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) LRR_7 PF13504.1 EMD68639.1 - 0.11 12.7 12.3 7.5 7.2 1.2 4.1 4 0 0 4 4 4 0 Leucine rich repeat CRAL_TRIO PF00650.15 EMD68640.1 - 1.1e-36 125.7 0.0 1.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD68640.1 - 9.3e-10 38.4 1.4 1.7e-09 37.6 0.4 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMD68640.1 - 1.9e-05 24.5 0.0 6.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mito_carr PF00153.22 EMD68641.1 - 2.2e-57 190.7 3.2 2.2e-22 78.5 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein MAM33 PF02330.11 EMD68642.1 - 1.1e-34 120.0 5.3 2.8e-26 92.5 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial glycoprotein BTB PF00651.26 EMD68643.1 - 1.1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HUN PF08729.5 EMD68645.1 - 5.9e-13 48.4 0.4 1e-12 47.6 0.3 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Nop PF01798.13 EMD68646.1 - 2.7e-58 195.5 0.1 2.7e-58 195.5 0.1 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD68646.1 - 1.7e-26 91.7 0.1 3.9e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMD68646.1 - 1.2e-19 70.1 0.0 1.2e-19 70.1 0.0 2.3 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EMD68646.1 - 0.00013 21.6 21.2 0.00021 21.0 14.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 V-ATPase_G PF03179.10 EMD68646.1 - 3.6 7.9 21.8 46 4.3 13.0 3.1 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit NARP1 PF12569.3 EMD68646.1 - 3.8 6.1 21.7 7.6 5.1 15.0 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cpn60_TCP1 PF00118.19 EMD68647.1 - 5.2e-152 506.8 0.4 5.8e-152 506.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_47 PF01532.15 EMD68648.1 - 9.1e-186 617.9 0.0 1.1e-185 617.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_12 PF01670.11 EMD68649.1 - 2.2e-43 147.7 1.1 2.2e-43 147.7 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 MARVEL PF01284.18 EMD68650.1 - 0.025 14.3 0.1 0.028 14.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associating domain GTP_EFTU PF00009.22 EMD68651.1 - 1.2e-37 129.1 2.6 8.7e-37 126.3 1.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMD68651.1 - 7.9e-23 80.4 0.5 1.8e-22 79.2 0.3 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMD68651.1 - 9.1e-11 41.7 9.0 8.1e-08 32.2 0.2 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EMD68651.1 - 8e-09 35.0 0.4 2.1e-08 33.6 0.0 2.0 2 0 0 2 2 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EMD68651.1 - 2.3e-07 30.7 0.1 5.4e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMD68651.1 - 2.3e-06 28.0 0.1 5.6e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EMD68651.1 - 8.2e-05 21.9 0.1 0.0002 20.6 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EMD68651.1 - 0.00019 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMD68651.1 - 0.00029 20.1 0.8 0.0019 17.4 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit zf-CCHC PF00098.18 EMD68651.1 - 0.0096 15.8 1.7 0.0096 15.8 1.2 2.0 2 0 0 2 2 2 1 Zinc knuckle Dynamin_N PF00350.18 EMD68651.1 - 0.032 14.0 2.2 9.1 6.0 0.3 3.5 2 1 1 3 3 3 0 Dynamin family GTP_EFTU_D4 PF14578.1 EMD68651.1 - 0.04 13.5 5.6 0.064 12.8 2.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EMD68651.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CheC PF04509.7 EMD68651.1 - 0.16 11.6 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 CheC-like family Cu_bind_like PF02298.12 EMD68652.1 - 0.077 12.7 0.3 0.46 10.3 0.2 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain p450 PF00067.17 EMD68653.1 - 5.1e-55 186.8 0.0 6.6e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prenylcys_lyase PF07156.9 EMD68654.1 - 2.4e-36 125.3 0.0 7.3e-36 123.8 0.0 1.7 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.19 EMD68654.1 - 2.3e-12 46.7 0.0 1.2e-05 24.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMD68654.1 - 6e-11 42.2 0.1 1.7e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD68654.1 - 3.8e-09 36.5 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EMD68654.1 - 5.3e-09 35.4 0.1 7.5e-06 25.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD68654.1 - 1.7e-07 31.5 0.2 0.0024 17.9 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD68654.1 - 3e-06 25.9 0.7 0.026 13.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMD68654.1 - 2.1e-05 24.4 0.2 0.0015 18.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EMD68654.1 - 0.00027 20.5 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain ApbA PF02558.11 EMD68654.1 - 0.0014 18.0 0.2 0.083 12.3 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EMD68654.1 - 0.0026 18.1 0.2 3 8.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMD68654.1 - 0.004 16.0 1.1 0.0065 15.3 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMD68654.1 - 0.0063 15.6 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EMD68654.1 - 0.0092 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EMD68654.1 - 0.01 14.9 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMD68654.1 - 0.018 14.7 0.1 0.35 10.5 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EMD68654.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 1 0 ThiF family FAD_binding_2 PF00890.19 EMD68654.1 - 0.026 13.3 0.5 0.04 12.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EMD68654.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMD68654.1 - 0.038 13.0 0.1 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MMTV_SAg PF01054.12 EMD68654.1 - 0.057 12.3 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen F420_oxidored PF03807.12 EMD68654.1 - 0.13 12.7 0.1 0.46 10.9 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2263 PF10021.4 EMD68656.1 - 5.1e-22 78.4 0.0 9.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EMD68656.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Macro domain DNA_pol_A_exo1 PF01612.15 EMD68657.1 - 9.4e-38 129.4 0.1 1.9e-37 128.4 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EMD68657.1 - 6e-27 93.7 0.0 6e-25 87.3 0.0 2.8 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EMD68657.1 - 2.5e-10 39.9 0.0 8.1e-10 38.2 0.0 2.0 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.7 EMD68658.1 - 9.5e-29 99.0 1.4 1.1e-28 98.8 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EMD68658.1 - 0.00083 19.3 0.6 0.0021 18.0 0.4 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EMD68658.1 - 0.0046 16.6 3.9 0.18 11.5 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EMD68658.1 - 0.0049 16.7 1.7 0.5 10.3 0.1 2.3 2 1 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein FeS PF04060.8 EMD68658.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster MAPEG PF01124.13 EMD68659.1 - 2.5e-20 72.4 2.3 2.9e-20 72.1 1.6 1.0 1 0 0 1 1 1 1 MAPEG family VHS PF00790.14 EMD68660.1 - 3.6e-48 162.7 0.2 1e-47 161.3 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EMD68660.1 - 1e-24 86.4 0.4 4.8e-24 84.2 0.1 2.3 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EMD68660.1 - 2.6e-18 66.3 4.5 4e-18 65.8 1.4 2.5 2 1 0 2 2 2 1 Adaptin C-terminal domain Mei5 PF10376.4 EMD68660.1 - 0.00095 18.7 1.3 0.0021 17.6 0.9 1.5 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF367 PF04034.8 EMD68661.1 - 5.6e-49 164.9 0.0 7.8e-49 164.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EMD68661.1 - 5.3e-10 38.7 0.6 1.1e-09 37.6 0.4 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI GLTSCR1 PF15249.1 EMD68661.1 - 0.84 9.7 0.0 0.84 9.7 0.0 3.3 2 2 0 2 2 2 0 Glioma tumor suppressor candidate region adh_short PF00106.20 EMD68662.1 - 2e-28 99.4 0.5 2.6e-28 99.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD68662.1 - 2.4e-24 86.4 0.0 3.1e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD68662.1 - 4.4e-11 42.7 0.2 6.1e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EMD68662.1 - 0.0073 15.3 0.4 0.016 14.2 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EMD68662.1 - 0.13 12.0 2.8 0.28 11.0 2.0 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Zn_clus PF00172.13 EMD68664.1 - 2.7e-08 33.5 13.9 5.3e-08 32.6 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD68664.1 - 1.3e-07 30.8 1.9 2.6e-07 29.7 0.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EMD68669.1 - 3.7e-78 262.5 0.0 8.3e-78 261.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMD68669.1 - 2.4e-47 161.8 0.0 5.6e-47 160.6 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMD68669.1 - 3.9e-32 110.5 3.0 3.9e-32 110.5 2.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EMD68669.1 - 1.6e-28 100.5 0.0 6.6e-28 98.4 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EMD68669.1 - 6.4e-21 74.3 7.4 2.4e-10 40.5 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EMD68669.1 - 1.3e-13 50.8 0.0 3.9e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EMD68669.1 - 1.4e-08 34.9 1.9 4.5e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD68669.1 - 2.3e-08 33.9 0.0 0.0016 18.2 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EMD68669.1 - 4.2e-05 22.6 0.2 0.0003 19.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EMD68669.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Prefoldin PF02996.12 EMD68670.1 - 3.2e-35 120.3 0.1 7.3e-35 119.2 0.0 1.6 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EMD68670.1 - 0.0002 21.0 0.2 0.0088 15.7 0.1 2.6 1 1 1 2 2 2 1 Prefoldin subunit Filament PF00038.16 EMD68670.1 - 0.0028 17.1 0.6 0.29 10.5 0.1 2.0 2 0 0 2 2 2 2 Intermediate filament protein HR1 PF02185.11 EMD68670.1 - 0.013 15.2 0.1 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Hr1 repeat MAD PF05557.8 EMD68670.1 - 0.024 12.7 1.1 0.08 11.0 0.0 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein Syntaxin-6_N PF09177.6 EMD68670.1 - 0.025 14.9 0.7 6 7.3 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EMD68670.1 - 0.042 13.6 0.1 6 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DIL PF01843.14 EMD68670.1 - 0.055 13.3 0.0 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 DIL domain Fmp27_WPPW PF10359.4 EMD68670.1 - 0.081 11.3 1.0 0.34 9.2 0.1 1.8 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Lebercilin PF15619.1 EMD68670.1 - 0.6 9.5 3.6 3.9 6.8 0.1 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.10 EMD68672.1 - 1.3e-28 99.6 0.9 2.3e-28 98.8 0.2 1.7 2 0 0 2 2 2 1 Sec34-like family RCC1 PF00415.13 EMD68673.1 - 7.9e-30 102.8 0.4 4.2e-05 23.6 0.0 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMD68673.1 - 6.6e-14 51.0 16.4 3.6e-07 29.6 0.0 6.4 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DnaJ PF00226.26 EMD68675.1 - 3.3e-07 29.9 0.4 6.3e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L31 PF01197.13 EMD68676.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31 KAR9 PF08580.5 EMD68676.1 - 0.16 10.2 1.1 0.17 10.0 0.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Flavin_Reduct PF01613.13 EMD68677.1 - 1e-22 80.6 0.2 2.2e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Flavin reductase like domain MaoC_dehydrat_N PF13452.1 EMD68677.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase LSM PF01423.17 EMD68678.1 - 1.3e-16 59.8 0.1 1.7e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD68678.1 - 4.5e-05 23.2 0.1 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain TauD PF02668.11 EMD68679.1 - 8e-23 81.4 0.0 1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.1 EMD68679.1 - 0.0014 19.0 0.1 0.0027 18.1 0.1 1.4 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 DUF1744 PF08490.7 EMD68680.1 - 4.2e-144 479.9 0.0 5.9e-144 479.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EMD68680.1 - 1.2e-64 218.2 2.9 2.1e-64 217.4 2.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EMD68680.1 - 7.4e-24 84.3 0.1 4.7e-23 81.7 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EMD68680.1 - 6.3e-10 38.9 0.1 2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMD68680.1 - 1.1e-05 25.2 0.1 6.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EMD68681.1 - 2.5e-32 111.0 0.8 3.4e-32 110.5 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF677 PF05055.7 EMD68681.1 - 0.077 11.6 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SHR3_chaperone PF08229.6 EMD68681.1 - 0.11 11.4 0.3 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 PBP_sp32 PF07222.7 EMD68681.1 - 0.71 9.0 7.9 0.97 8.5 5.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Methyltransf_26 PF13659.1 EMD68682.1 - 9.9e-19 67.5 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD68682.1 - 0.00015 21.2 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMD68682.1 - 0.0062 16.9 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD68682.1 - 0.046 13.3 0.0 0.073 12.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 EMD68683.1 - 2.5e-10 39.9 0.1 6e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMD68683.1 - 6.2e-08 32.7 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMD68683.1 - 1.4e-06 28.7 0.7 8.5e-06 26.1 0.5 1.9 1 1 0 1 1 1 1 Complex1_LYR-like PaaSYMP PF14738.1 EMD68683.1 - 0.014 15.0 0.5 0.019 14.6 0.3 1.1 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 CSTF2_hinge PF14327.1 EMD68683.1 - 0.028 14.5 0.2 0.042 13.9 0.2 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 PMT_C PF11647.3 EMD68683.1 - 0.046 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 HBS1_N PF08938.5 EMD68683.1 - 0.051 13.6 0.5 0.067 13.3 0.3 1.3 1 0 0 1 1 1 0 HBS1 N-terminus zf-RING_3 PF14369.1 EMD68684.1 - 0.041 13.8 0.1 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 zinc-finger Ribosomal_L29e PF01779.12 EMD68685.1 - 5.6e-22 77.3 13.2 9.7e-22 76.5 9.2 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family AMMECR1 PF01871.12 EMD68686.1 - 3.2e-49 166.3 0.0 7.2e-49 165.1 0.0 1.5 2 0 0 2 2 2 1 AMMECR1 Sporozoite_P67 PF05642.6 EMD68686.1 - 0.47 8.2 4.9 0.64 7.8 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C14 PF00656.17 EMD68687.1 - 5.1e-71 239.2 0.0 6.2e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Sec7 PF01369.15 EMD68688.1 - 9.8e-36 123.2 0.0 2.2e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMD68688.1 - 4.1e-19 68.8 0.0 1.1e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain CBS PF00571.23 EMD68689.1 - 2.8e-21 75.0 3.8 1.8e-06 27.6 0.0 5.4 5 0 0 5 5 5 5 CBS domain DUF3348 PF11828.3 EMD68689.1 - 0.0093 15.4 0.3 0.015 14.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) tRNA-synt_2b PF00587.20 EMD68691.1 - 1e-43 148.9 0.1 2.2e-43 147.8 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD68691.1 - 7.2e-18 64.3 0.6 1.6e-17 63.2 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EMD68691.1 - 1.4e-13 50.4 0.1 3.4e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EMD68691.1 - 2e-10 40.3 0.0 4.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 EMD68692.1 - 1.6e-35 121.8 0.1 1.6e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MARVEL PF01284.18 EMD68694.1 - 0.0019 18.0 11.2 0.0046 16.7 7.7 1.7 1 1 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EMD68694.1 - 0.32 10.2 14.3 0.23 10.7 8.3 1.8 1 1 1 2 2 2 0 Tetraspanin family BPD_transp_2 PF02653.11 EMD68694.1 - 0.71 8.7 16.1 3.6 6.4 9.6 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Whi5 PF08528.6 EMD68697.1 - 5e-10 38.7 0.1 1.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.3 EMD68698.1 - 1e-167 557.8 0.0 1.3e-167 557.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EMD68698.1 - 0.015 15.1 0.0 0.13 12.1 0.0 2.4 2 1 1 3 3 3 0 Jacalin-like lectin domain Reprolysin_2 PF13574.1 EMD68698.1 - 0.04 13.9 0.3 0.088 12.8 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMD68698.1 - 0.083 12.4 0.3 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ACPS PF01648.15 EMD68698.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Reprolysin_5 PF13688.1 EMD68698.1 - 0.32 10.8 3.5 0.12 12.2 0.4 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 CDP-OH_P_transf PF01066.16 EMD68699.1 - 1.1e-13 51.3 2.5 2.2e-13 50.3 1.7 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Mob1_phocein PF03637.12 EMD68699.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Mob1/phocein family Aminotran_1_2 PF00155.16 EMD68700.1 - 1.1e-36 126.5 0.0 1.4e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glucan_synthase PF02364.10 EMD68701.1 - 0 1457.1 0.0 0 1456.6 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMD68701.1 - 7.9e-38 128.9 0.1 1.9e-37 127.7 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EMD68702.1 - 8.3e-129 429.0 5.2 1.1e-128 428.7 3.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMD68702.1 - 1.3e-19 70.3 3.8 3.6e-19 69.0 2.6 1.8 1 0 0 1 1 1 1 X8 domain Period_C PF12114.3 EMD68702.1 - 7.9 6.0 6.5 15 5.0 4.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Gln-synt_C PF00120.19 EMD68703.1 - 1.2e-42 145.8 0.0 1.8e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EMD68703.1 - 3e-25 89.3 0.1 5.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MR_MLE_C PF13378.1 EMD68703.1 - 0.02 14.8 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like FUR PF01475.14 EMD68704.1 - 0.1 12.4 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Ferric uptake regulator family WSC PF01822.14 EMD68705.1 - 8.5e-14 51.2 7.2 8.5e-14 51.2 5.0 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMD68705.1 - 4.3e-08 32.3 0.1 4.3e-08 32.3 0.1 2.6 3 0 0 3 3 3 2 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EMD68705.1 - 0.028 12.7 0.0 0.037 12.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EMD68705.1 - 0.037 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4381 PF14316.1 EMD68705.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PepSY_TM_2 PF13703.1 EMD68705.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix VPEP PF07589.6 EMD68705.1 - 6.7 6.7 6.3 19 5.3 4.3 1.8 1 0 0 1 1 1 0 PEP-CTERM motif PH PF00169.24 EMD68706.1 - 1.8e-09 37.7 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EMD68706.1 - 0.01 13.4 0.8 0.015 12.8 0.5 1.1 1 0 0 1 1 1 0 Prominin DUF269 PF03270.8 EMD68706.1 - 0.01 15.8 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF269 Inhibitor_I10 PF12559.3 EMD68706.1 - 0.02 15.1 0.2 5.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Serine endopeptidase inhibitors DUF4615 PF15393.1 EMD68706.1 - 0.047 13.9 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Glyco_hydro_61 PF03443.9 EMD68707.1 - 2.9e-57 194.0 0.2 3.3e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TIG PF01833.19 EMD68707.1 - 0.0033 17.3 1.7 0.32 11.0 0.1 2.2 2 0 0 2 2 2 2 IPT/TIG domain ADH_zinc_N PF00107.21 EMD68708.1 - 8.8e-14 51.1 0.0 1.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD68708.1 - 4e-11 43.9 0.3 7.8e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD68708.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 EMD68708.1 - 0.0061 15.7 0.0 0.0086 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) UCH PF00443.24 EMD68709.1 - 4.5e-59 199.7 0.3 6.5e-59 199.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD68709.1 - 1.4e-32 113.2 0.1 2.2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMD68709.1 - 1.3e-06 28.3 3.5 1.6e-06 28.0 0.2 2.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein COesterase PF00135.23 EMD68711.1 - 1e-71 242.3 0.5 1.3e-71 241.9 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD68711.1 - 0.0015 18.1 0.3 0.011 15.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD68711.1 - 0.0018 18.0 0.2 0.0041 16.8 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family NUFIP2 PF15293.1 EMD68711.1 - 0.067 11.9 0.1 0.098 11.3 0.1 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Gmx_para_CXXCG PF09535.5 EMD68712.1 - 0.071 12.1 1.2 0.1 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF3431 PF11913.3 EMD68713.1 - 1.7e-18 66.9 0.4 2.9e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4131 PF13567.1 EMD68713.1 - 4.4 6.6 17.3 2.8 7.3 0.1 4.3 3 1 1 5 5 5 0 Domain of unknown function (DUF4131) adh_short PF00106.20 EMD68715.1 - 3.4e-16 59.6 0.0 4e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68715.1 - 6.9e-06 25.8 0.0 8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain RPAP1_C PF08620.5 EMD68717.1 - 8.9e-30 102.3 0.0 1.7e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EMD68717.1 - 3.3e-16 58.5 4.9 6.5e-16 57.6 3.4 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Glyoxalase PF00903.20 EMD68718.1 - 6.5e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMD68718.1 - 2.2e-13 50.7 0.1 8.7e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMD68718.1 - 1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMD68718.1 - 0.11 12.4 0.0 0.53 10.1 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain UCH PF00443.24 EMD68719.1 - 5.9e-35 120.6 0.0 1.3e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EMD68719.1 - 3.9e-30 103.0 1.9 3.9e-20 71.0 0.1 4.7 5 0 0 5 5 5 3 A repeated domain in UCH-protein UCH_1 PF13423.1 EMD68719.1 - 3.2e-09 36.6 0.0 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Totivirus_coat PF05518.6 EMD68719.1 - 0.44 8.3 6.0 0.67 7.7 4.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein Tim17 PF02466.14 EMD68720.1 - 3.4e-07 30.3 9.2 1e-06 28.8 6.4 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.7 EMD68721.1 - 9.5e-33 112.1 1.4 1.5e-32 111.5 1.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Cob_adeno_trans PF01923.13 EMD68721.1 - 0.068 12.9 0.1 0.48 10.2 0.1 2.1 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Snapin_Pallidin PF14712.1 EMD68721.1 - 0.2 11.9 0.5 3 8.2 0.2 2.4 2 1 1 3 3 3 0 Snapin/Pallidin S-methyl_trans PF02574.11 EMD68724.1 - 2.5e-78 263.4 0.0 3e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Med11 PF10280.4 EMD68725.1 - 3.8e-09 36.6 0.1 4.5e-08 33.1 0.0 2.2 1 1 1 2 2 2 1 Mediator complex protein WD40 PF00400.27 EMD68726.1 - 8.5e-58 190.3 18.8 9.4e-11 41.1 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMD68726.1 - 4.7e-45 153.1 0.3 6.6e-45 152.6 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EMD68726.1 - 1.7e-06 27.5 0.1 3.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EMD68726.1 - 9.5e-06 24.0 6.4 0.19 9.8 0.0 3.6 3 1 0 4 4 4 3 Nucleoporin Nup120/160 IKI3 PF04762.7 EMD68726.1 - 0.072 10.9 0.1 0.13 10.0 0.1 1.4 1 0 0 1 1 1 0 IKI3 family Med9 PF07544.8 EMD68727.1 - 2.9e-21 74.9 0.9 4.9e-21 74.2 0.7 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 EMD68727.1 - 0.0091 15.9 9.7 0.015 15.3 6.7 1.4 1 1 0 1 1 1 1 Subunit 21 of Mediator complex IncA PF04156.9 EMD68727.1 - 0.0094 15.5 0.6 0.012 15.2 0.4 1.1 1 0 0 1 1 1 1 IncA protein SlyX PF04102.7 EMD68727.1 - 0.0099 16.2 0.8 0.027 14.8 0.6 1.8 1 0 0 1 1 1 1 SlyX AATF-Che1 PF13339.1 EMD68727.1 - 0.016 15.3 0.5 0.026 14.6 0.3 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Viral_P18 PF04521.8 EMD68727.1 - 0.028 13.8 0.2 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 EMD68727.1 - 0.034 13.6 2.0 0.049 13.1 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1993 PF09351.5 EMD68727.1 - 0.051 13.5 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) HR1 PF02185.11 EMD68727.1 - 0.073 12.8 3.2 0.12 12.1 2.2 1.4 1 1 0 1 1 1 0 Hr1 repeat FlxA PF14282.1 EMD68727.1 - 0.086 12.7 1.6 0.11 12.4 1.1 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF4424 PF14415.1 EMD68727.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) TBPIP PF07106.8 EMD68727.1 - 0.18 11.3 0.8 0.24 10.9 0.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 EMD68727.1 - 0.19 11.4 1.7 0.24 11.0 0.9 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HalX PF08663.5 EMD68727.1 - 0.27 11.2 3.5 0.43 10.6 2.4 1.3 1 0 0 1 1 1 0 HalX domain DUF4140 PF13600.1 EMD68727.1 - 0.7 10.3 4.2 1.7 9.0 2.9 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PEP-utilisers_N PF05524.8 EMD68727.1 - 1.4 8.7 4.9 5.5 6.8 2.1 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Metalloenzyme PF01676.13 EMD68728.1 - 7.6e-75 251.5 0.2 8.8e-75 251.3 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EMD68728.1 - 6.7e-69 231.6 0.0 1.1e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EMD68728.1 - 7.7e-07 28.7 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMD68728.1 - 2.9e-06 26.7 0.0 0.00062 19.0 0.0 3.0 2 1 0 2 2 2 2 Sulfatase Alk_phosphatase PF00245.15 EMD68728.1 - 0.001 17.8 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.7 EMD68728.1 - 0.019 14.6 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Pkinase PF00069.20 EMD68729.1 - 2.5e-68 230.0 0.0 3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD68729.1 - 2.2e-27 95.8 0.0 2.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD68729.1 - 1.4e-06 27.4 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD68729.1 - 0.00031 20.5 0.3 0.00056 19.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMD68729.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMD68729.1 - 0.067 12.5 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Peptidase_C15 PF01470.12 EMD68730.1 - 2.5e-09 37.2 0.0 0.00042 20.2 0.0 2.4 2 1 0 2 2 2 2 Pyroglutamyl peptidase FAD_binding_3 PF01494.14 EMD68731.1 - 1.8e-13 50.2 4.7 8.9e-11 41.4 0.5 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMD68731.1 - 1.7e-06 27.9 0.3 6.7e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD68731.1 - 3.9e-05 23.4 0.9 0.014 15.2 0.2 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding SE PF08491.5 EMD68731.1 - 6e-05 22.0 0.0 0.00017 20.5 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EMD68731.1 - 0.00067 18.6 0.2 0.0013 17.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD68731.1 - 0.0057 17.0 0.4 0.016 15.6 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD68731.1 - 0.0085 16.1 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD68731.1 - 0.026 14.4 0.2 0.083 12.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMD68731.1 - 0.037 13.0 0.1 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Abhydrolase_1 PF00561.15 EMD68732.1 - 6.2e-09 35.7 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD68732.1 - 1.5e-08 34.7 0.0 3.2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD68732.1 - 2.7e-08 33.7 0.0 7.5e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMD68732.1 - 0.0029 16.8 0.0 0.047 12.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EMD68732.1 - 0.0086 15.9 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S37 PF05576.6 EMD68732.1 - 0.017 13.5 0.0 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 PS-10 peptidase S37 Esterase PF00756.15 EMD68732.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Kelch_3 PF13415.1 EMD68733.1 - 2.8e-28 97.3 14.8 5e-09 36.0 0.0 7.6 9 0 0 9 9 9 5 Galactose oxidase, central domain DUF4110 PF13422.1 EMD68733.1 - 1.3e-27 95.4 0.4 1.3e-27 95.4 0.3 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EMD68733.1 - 4.8e-25 87.0 13.2 1.5e-06 27.8 0.0 7.3 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD68733.1 - 1e-22 79.6 0.6 5.7e-07 29.3 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EMD68733.1 - 7.3e-21 73.4 8.5 4.6e-05 23.4 0.1 6.3 5 2 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EMD68733.1 - 8.5e-17 60.4 1.3 1.1e-06 28.0 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMD68733.1 - 9.9e-14 50.4 4.9 0.016 14.9 0.1 6.1 6 1 0 6 6 6 3 Kelch motif CENP-B_dimeris PF09026.5 EMD68733.1 - 6.1 7.1 23.6 18 5.6 0.2 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OB_NTP_bind PF07717.11 EMD68734.1 - 6e-21 74.3 0.0 1.9e-20 72.7 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMD68734.1 - 3.5e-15 55.8 0.0 1.2e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMD68734.1 - 8.6e-13 47.9 0.0 2.7e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMD68734.1 - 1e-06 28.8 0.1 5.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EMD68734.1 - 1.2e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.22 EMD68734.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 EMD68734.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EMD68734.1 - 0.0045 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 EMD68734.1 - 0.0067 15.1 0.7 0.014 14.1 0.5 1.4 1 0 0 1 1 1 1 G-protein alpha subunit AAA_30 PF13604.1 EMD68734.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMD68734.1 - 0.019 14.7 0.3 0.11 12.3 0.2 2.3 1 1 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EMD68734.1 - 0.026 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EMD68734.1 - 0.026 13.6 0.0 0.065 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DAP3 PF10236.4 EMD68734.1 - 0.045 12.6 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 EMD68734.1 - 0.083 11.9 0.1 0.56 9.2 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_16 PF13191.1 EMD68734.1 - 0.092 12.7 3.8 0.52 10.2 0.1 3.2 3 2 0 3 3 3 0 AAA ATPase domain Peptidase_M3 PF01432.15 EMD68735.1 - 6.6e-124 414.4 0.0 8.4e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 PA28_beta PF02252.13 EMD68735.1 - 0.14 11.5 0.6 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit Peptidase_M50B PF13398.1 EMD68735.1 - 0.2 10.9 0.2 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 EMD68736.1 - 1.6e-44 151.4 0.7 3e-44 150.4 0.1 1.8 1 1 1 2 2 2 1 Apolipoprotein O Methyltransf_23 PF13489.1 EMD68737.1 - 1.6e-21 76.6 0.1 3.2e-21 75.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD68737.1 - 2.9e-09 36.7 0.0 8.5e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD68737.1 - 6.1e-09 36.4 0.0 3.8e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD68737.1 - 8.3e-07 29.4 0.0 2.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMD68737.1 - 7e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EMD68737.1 - 7.8e-05 23.1 0.0 0.0002 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMD68737.1 - 0.00011 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EMD68737.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMD68737.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMD68737.1 - 0.0054 15.4 0.0 0.088 11.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MTS PF05175.9 EMD68737.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMD68737.1 - 0.013 14.6 0.0 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EMD68737.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EMD68737.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.13 EMD68737.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Gpi1 PF05024.10 EMD68738.1 - 1.3e-60 204.3 8.4 2.1e-60 203.6 5.9 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF454 PF04304.8 EMD68739.1 - 0.019 14.9 0.1 0.019 14.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF454) zf-CCCH PF00642.19 EMD68740.1 - 0.00096 18.7 3.2 0.0019 17.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 EMD68740.1 - 0.06 13.5 189.4 0.051 13.8 32.3 6.3 2 1 3 5 5 5 0 Nucleoporin FG repeat region Apc1 PF12859.2 EMD68741.1 - 1.8e-25 89.1 0.3 1.4e-24 86.2 0.2 2.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EMD68741.1 - 0.056 13.7 6.7 0.69 10.2 0.0 4.4 5 0 0 5 5 5 0 Proteasome/cyclosome repeat GTP_EFTU PF00009.22 EMD68743.1 - 8.6e-10 38.3 0.1 4.5e-09 36.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMD68743.1 - 0.013 14.3 0.8 0.34 9.6 0.1 2.7 3 0 0 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 EMD68743.1 - 0.02 14.4 1.2 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EMD68743.1 - 0.041 12.5 0.2 0.099 11.3 0.1 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 EMD68743.1 - 0.13 11.8 0.5 0.34 10.4 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytochrom_B559 PF00283.14 EMD68744.1 - 0.23 10.7 1.6 0.38 10.0 0.2 2.1 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits zf-C2H2_4 PF13894.1 EMD68745.1 - 7.8e-05 22.7 4.1 0.018 15.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD68745.1 - 0.016 15.5 6.7 0.33 11.3 0.4 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMD68745.1 - 0.11 12.4 4.6 3 7.8 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Cys_Met_Meta_PP PF01053.15 EMD68747.1 - 1e-34 119.5 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMD68747.1 - 0.0078 15.1 0.0 0.027 13.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DUF1633 PF07794.6 EMD68748.1 - 0.002 16.2 1.2 0.0026 15.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Uds1 PF15456.1 EMD68748.1 - 0.028 14.4 3.0 0.028 14.4 2.1 3.2 2 1 2 4 4 4 0 Up-regulated During Septation DUF4559 PF15112.1 EMD68748.1 - 0.028 13.5 5.6 0.016 14.4 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) CENP-F_leu_zip PF10473.4 EMD68748.1 - 0.03 14.1 1.0 0.03 14.1 0.7 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EMD68748.1 - 0.052 13.7 7.6 0.11 12.8 0.0 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 EMD68748.1 - 0.064 13.6 11.1 0.081 13.3 2.1 3.6 2 2 1 3 3 3 0 SlyX DUF677 PF05055.7 EMD68748.1 - 0.15 10.6 3.7 0.089 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF677) YlqD PF11068.3 EMD68748.1 - 0.86 9.6 10.8 0.045 13.8 1.2 2.7 1 1 1 2 2 2 0 YlqD protein TMF_DNA_bd PF12329.3 EMD68748.1 - 1.2 8.9 15.3 0.13 12.1 1.9 3.5 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding FliD_N PF02465.13 EMD68748.1 - 1.4 9.3 8.5 0.31 11.4 1.8 2.8 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TBPIP PF07106.8 EMD68748.1 - 1.9 8.0 13.0 0.11 12.0 2.4 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EMD68748.1 - 1.9 8.6 10.3 3.4 7.9 2.2 3.1 1 1 2 3 3 3 0 Syntaxin PCMT PF01135.14 EMD68749.1 - 1.3e-68 230.6 0.0 1.5e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EMD68749.1 - 4e-11 43.4 0.0 6.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD68749.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD68749.1 - 2.3e-05 24.1 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD68749.1 - 0.00011 22.6 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD68749.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMD68749.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMD68749.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMD68749.1 - 0.00048 19.5 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EMD68749.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW GCD14 PF08704.5 EMD68749.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 EMD68749.1 - 0.0016 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMD68749.1 - 0.0028 17.6 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EMD68749.1 - 0.0035 16.5 0.1 0.0056 15.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EMD68749.1 - 0.0076 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EMD68749.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EMD68749.1 - 0.018 15.8 0.0 0.054 14.3 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Fibrillarin PF01269.12 EMD68749.1 - 0.034 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Nrap PF03813.9 EMD68750.1 - 0 1135.2 0.0 0 1135.0 0.0 1.0 1 0 0 1 1 1 1 Nrap protein SDA1 PF05285.7 EMD68750.1 - 0.019 14.2 15.0 0.036 13.3 10.4 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EMD68750.1 - 0.36 9.8 21.7 0.81 8.6 15.1 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EMD68750.1 - 0.41 8.4 19.4 0.62 7.9 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family COesterase PF00135.23 EMD68751.1 - 2.8e-47 161.6 3.0 2e-45 155.5 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD68751.1 - 5.9e-07 29.2 0.1 0.0067 16.0 0.1 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD68751.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD68751.1 - 0.003 17.3 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 EMD68752.1 - 1.1e-18 67.7 0.0 2.4e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68752.1 - 0.00018 21.2 0.0 0.012 15.2 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD68752.1 - 0.0022 17.8 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PAS_10 PF13596.1 EMD68752.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 PAS domain Epimerase PF01370.16 EMD68752.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EMD68753.1 - 2e-69 234.3 0.0 2.4e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EMD68754.1 - 1.1e-29 103.8 0.3 1.4e-29 103.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD68754.1 - 5.9e-18 65.2 0.0 3.4e-15 56.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD68754.1 - 2.2e-10 40.4 0.0 7e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD68754.1 - 3e-05 23.7 0.2 5.5e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EMD68754.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein AXE1 PF05448.7 EMD68754.1 - 0.01 14.3 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mito_carr PF00153.22 EMD68755.1 - 5.3e-66 218.3 0.0 6.9e-22 76.9 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein F-box-like PF12937.2 EMD68756.1 - 7.1e-09 35.2 0.2 1.4e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD68756.1 - 0.00024 20.6 0.4 0.00048 19.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 EMD68756.1 - 0.0018 18.0 0.2 1.8 8.6 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD68756.1 - 0.0019 17.7 0.1 0.38 10.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD68756.1 - 0.0052 16.3 0.1 0.07 12.7 0.0 2.3 1 1 1 2 2 2 2 TPR repeat MIT PF04212.13 EMD68756.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cpn60_TCP1 PF00118.19 EMD68757.1 - 1.3e-140 469.2 5.0 1.5e-140 469.0 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box-like PF12937.2 EMD68758.1 - 0.071 12.8 0.4 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EMD68758.1 - 0.14 11.8 3.9 0.79 9.4 2.7 2.2 1 1 0 1 1 1 0 F-box domain MFS_1 PF07690.11 EMD68759.1 - 4.9e-23 81.4 83.0 6e-21 74.5 34.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OmdA PF13376.1 EMD68761.1 - 6.6e-10 38.4 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated ELYS PF13934.1 EMD68762.1 - 8.6e-66 221.9 0.1 9.9e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly Fungal_trans PF04082.13 EMD68763.1 - 1.1e-11 44.1 0.4 1.5e-11 43.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68763.1 - 5.8e-10 38.9 7.3 1.1e-09 38.0 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_9 PF14658.1 EMD68763.1 - 0.046 13.6 0.8 1 9.3 0.0 3.1 3 1 1 4 4 4 0 EF-hand domain MFS_1 PF07690.11 EMD68764.1 - 2.3e-35 121.9 39.7 2.3e-35 121.9 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD68764.1 - 1.5e-08 33.6 38.2 2.8e-07 29.4 26.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1673 PF07895.6 EMD68764.1 - 0.3 10.5 2.7 0.42 10.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Ytp1 PF10355.4 EMD68765.1 - 2.5e-111 371.2 13.1 2.5e-111 371.2 9.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMD68765.1 - 1.3e-25 88.9 8.4 1.3e-25 88.9 5.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DASH_Dam1 PF08653.5 EMD68766.1 - 1.9e-27 94.7 0.7 2.6e-27 94.3 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Neogenin_C PF06583.7 EMD68766.1 - 0.051 13.1 0.6 0.051 13.1 0.4 1.6 2 0 0 2 2 2 0 Neogenin C-terminus CRAL_TRIO PF00650.15 EMD68767.1 - 7e-44 149.1 0.0 1.3e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD68767.1 - 2.7e-17 62.6 0.4 1.5e-16 60.2 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMD68767.1 - 1.3e-09 38.1 0.0 7e-09 35.7 0.0 2.0 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain Ribosomal_S2 PF00318.15 EMD68768.1 - 1.9e-49 167.7 0.0 2.9e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 DsbC PF11412.3 EMD68768.1 - 0.095 12.5 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Disulphide bond corrector protein DsbC PAS_9 PF13426.1 EMD68769.1 - 1.5e-28 99.2 0.0 1.2e-15 57.7 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EMD68769.1 - 8.2e-18 64.2 0.0 1.2e-10 41.2 0.0 4.1 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EMD68769.1 - 3.5e-15 55.0 8.5 8.4e-15 53.8 5.9 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EMD68769.1 - 1.3e-13 50.6 0.0 7.2e-06 25.7 0.0 4.3 4 1 0 4 4 4 3 PAS fold PAS_11 PF14598.1 EMD68769.1 - 5.7e-09 35.9 0.0 0.0027 17.6 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EMD68769.1 - 6.8e-06 26.0 0.0 0.043 13.8 0.0 3.5 3 0 0 3 3 3 2 PAS fold Cytochrom_c3_2 PF14537.1 EMD68769.1 - 0.059 13.7 3.2 0.16 12.3 2.2 1.7 1 0 0 1 1 1 0 Cytochrome c3 Ras PF00071.17 EMD68770.1 - 1.7e-40 138.1 0.0 2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD68770.1 - 2.5e-13 50.5 0.0 3.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD68770.1 - 5.1e-05 22.5 0.0 6.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMD68770.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMD68770.1 - 0.0012 18.3 0.0 0.032 13.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PRK PF00485.13 EMD68770.1 - 0.091 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Flocculin_t3 PF13928.1 EMD68770.1 - 0.17 12.0 2.1 0.4 10.8 1.5 1.6 1 1 0 1 1 1 0 Flocculin type 3 repeat Mito_carr PF00153.22 EMD68771.1 - 1.8e-63 210.2 4.6 1.9e-22 78.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.22 EMD68774.1 - 0.0044 16.4 0.1 0.0044 16.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EABR PF12180.3 EMD68774.1 - 0.75 9.2 3.7 10 5.5 2.6 2.1 1 1 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 SGL PF08450.7 EMD68776.1 - 0.076 12.3 0.1 0.31 10.4 0.0 1.9 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EMD68776.1 - 0.082 11.9 0.4 0.16 11.0 0.3 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Glyco_transf_90 PF05686.7 EMD68777.1 - 7.4e-39 133.5 2.1 9.2e-39 133.2 1.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EMD68777.1 - 0.004 17.4 0.1 0.0072 16.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.26 EMD68778.1 - 2.1e-23 81.7 0.7 2.1e-23 81.7 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 EMD68778.1 - 1.4e-11 44.2 9.2 1.5e-08 34.5 1.7 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD68778.1 - 9.6e-11 41.5 13.8 5.4e-10 39.1 5.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD68778.1 - 1e-05 25.5 8.7 0.0025 17.9 2.1 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMD68778.1 - 0.0001 22.3 5.6 0.051 13.9 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD68778.1 - 0.00057 20.0 7.6 0.11 12.8 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Herpes_LMP1 PF05297.6 EMD68778.1 - 0.071 12.0 10.2 0.097 11.5 7.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-LYAR PF08790.6 EMD68778.1 - 0.18 11.5 2.3 0.33 10.6 0.2 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SPX PF03105.14 EMD68779.1 - 8.2e-35 120.9 0.0 1.6e-34 119.9 0.0 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EMD68779.1 - 2.7e-07 30.3 13.5 3e-07 30.1 8.1 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMD68779.1 - 8e-07 28.7 10.6 2e-06 27.5 7.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD68779.1 - 5.2e-06 26.0 12.3 1.4e-05 24.6 8.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD68779.1 - 1.2e-05 24.9 9.2 2.3e-05 23.9 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD68779.1 - 1.7e-05 24.4 10.9 7.2e-05 22.4 7.6 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD68779.1 - 0.00043 20.2 12.4 0.001 19.0 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 EMD68779.1 - 0.00065 19.6 2.1 0.0013 18.6 1.4 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_UBOX PF13445.1 EMD68779.1 - 0.0081 15.8 7.9 0.0081 15.8 5.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EMD68779.1 - 0.03 13.8 6.6 0.071 12.6 4.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1660 PF07874.6 EMD68779.1 - 0.15 12.3 2.4 0.63 10.3 1.7 2.2 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-MIZ PF02891.15 EMD68779.1 - 0.2 11.2 12.2 0.46 10.0 8.3 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EMD68779.1 - 0.27 11.0 2.9 0.61 9.9 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EMD68779.1 - 0.62 9.9 6.9 1.8 8.4 4.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_4 PF07975.7 EMD68779.1 - 2.9 7.9 8.5 1.1 9.2 2.8 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_4 PF14570.1 EMD68779.1 - 3.9 7.1 17.0 1.9 8.1 8.5 2.8 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain DUF2370 PF10176.4 EMD68780.1 - 1.9e-84 282.6 0.9 2.3e-84 282.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 EMD68780.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Cwf_Cwc_15 PF04889.7 EMD68780.1 - 0.39 10.3 4.1 0.61 9.7 2.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GRIM-19 PF06212.7 EMD68782.1 - 3.4e-24 84.9 0.1 6.7e-24 84.0 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EMD68783.1 - 4.2e-33 114.5 0.7 1.5e-30 106.1 0.0 2.8 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase TLD PF07534.11 EMD68784.1 - 1.1e-26 93.4 0.0 3.7e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 TLD zf-RING_2 PF13639.1 EMD68786.1 - 1.2e-06 28.1 2.9 2.2e-06 27.3 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 EMD68786.1 - 0.0013 18.3 1.4 0.0024 17.5 1.0 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EMD68786.1 - 0.0028 17.3 3.0 0.0031 17.2 1.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EMD68786.1 - 0.0051 16.5 2.7 0.012 15.2 1.9 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4206 PF13901.1 EMD68786.1 - 0.0086 15.6 2.0 0.011 15.2 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-rbx1 PF12678.2 EMD68786.1 - 0.014 15.4 3.6 0.025 14.6 2.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD68786.1 - 0.027 14.4 2.9 0.066 13.2 2.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EMD68786.1 - 0.072 13.0 2.6 0.12 12.3 1.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 EMD68786.1 - 0.09 12.4 3.4 0.2 11.3 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMD68786.1 - 0.42 10.3 4.6 1.4 8.7 3.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.2 EMD68786.1 - 1.3 9.0 7.5 0.65 10.0 3.3 2.0 2 1 0 2 2 1 0 RING-variant domain FA_desaturase PF00487.19 EMD68787.1 - 3e-17 62.9 17.2 3.6e-17 62.6 11.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMD68787.1 - 2.8e-14 52.6 0.0 5.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDCD2_C PF04194.8 EMD68788.1 - 6.5e-56 188.4 0.0 7.6e-55 184.9 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF605 PF04652.11 EMD68788.1 - 1.6 8.0 12.0 2.2 7.5 8.3 1.1 1 0 0 1 1 1 0 Vta1 like PCI_Csn8 PF10075.4 EMD68789.1 - 9.5e-36 122.6 0.0 1.5e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EMD68789.1 - 3.8e-25 88.6 0.0 5.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Peptidase_S41 PF03572.13 EMD68790.1 - 9.5e-07 28.3 0.0 3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 SUI1 PF01253.17 EMD68791.1 - 4e-30 103.4 4.0 6e-30 102.8 2.8 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DNA_ligase_A_M PF01068.16 EMD68792.1 - 5.7e-50 169.4 0.1 7.6e-47 159.3 0.0 2.9 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMD68792.1 - 1.2e-40 139.1 0.2 2.2e-40 138.3 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMD68792.1 - 1.5e-18 66.9 0.1 9.3e-18 64.4 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Med14 PF08638.6 EMD68793.1 - 2.8e-51 173.5 0.2 6.6e-51 172.3 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 DUF4407 PF14362.1 EMD68793.1 - 0.32 9.9 11.2 0.66 8.8 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG22 PF11700.3 EMD68794.1 - 1.7e-207 689.6 13.9 2e-207 689.3 9.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EMD68794.1 - 3.6e-05 22.6 54.5 3.6e-05 22.6 16.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily TBPIP PF07106.8 EMD68795.1 - 2.6e-36 124.7 1.7 3.1e-36 124.4 1.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EMD68795.1 - 2.8e-05 23.8 0.3 7.8e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TPM PF04536.9 EMD68795.1 - 0.0011 18.7 2.3 0.35 10.7 0.0 3.1 3 0 0 3 3 3 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Penicillinase_R PF03965.11 EMD68795.1 - 0.0022 18.0 0.3 0.0048 16.9 0.0 1.8 2 1 0 2 2 2 1 Penicillinase repressor MarR_2 PF12802.2 EMD68795.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 MarR family DUF3811 PF11656.3 EMD68795.1 - 0.0042 17.1 4.3 0.007 16.4 1.2 2.3 2 0 0 2 2 2 1 YjbD family (DUF3811) Mnd1 PF03962.10 EMD68795.1 - 0.0044 16.7 0.9 0.0067 16.1 0.6 1.3 1 0 0 1 1 1 1 Mnd1 family Rrf2 PF02082.15 EMD68795.1 - 0.01 15.9 1.3 0.57 10.3 0.1 2.3 1 1 0 2 2 2 0 Transcriptional regulator RNA_pol_Rpc34 PF05158.7 EMD68795.1 - 0.011 14.9 1.1 0.016 14.4 0.2 1.6 1 1 0 2 2 2 0 RNA polymerase Rpc34 subunit CtsR PF05848.6 EMD68795.1 - 0.051 13.5 0.5 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 Firmicute transcriptional repressor of class III stress genes (CtsR) HutP PF09021.6 EMD68795.1 - 0.059 13.5 0.7 0.12 12.5 0.1 1.8 2 1 0 2 2 2 0 HutP DivIC PF04977.10 EMD68795.1 - 0.12 11.9 1.8 0.92 9.0 0.0 2.7 2 1 0 2 2 2 0 Septum formation initiator FUSC PF04632.7 EMD68795.1 - 0.5 8.7 4.2 0.61 8.4 2.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.16 EMD68795.1 - 2.1 8.3 6.9 28 4.7 0.0 3.4 2 1 1 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EMD68795.1 - 4.4 7.0 7.9 0.26 11.0 1.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA PF00004.24 EMD68796.1 - 6.6e-39 133.1 0.0 1.4e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMD68796.1 - 5e-08 32.7 0.0 0.00012 21.9 0.0 3.2 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EMD68796.1 - 2.4e-06 27.7 0.1 0.00015 21.9 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMD68796.1 - 3.1e-05 23.1 0.0 5.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMD68796.1 - 0.0002 21.2 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMD68796.1 - 0.00047 19.8 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMD68796.1 - 0.00067 18.4 0.1 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EMD68796.1 - 0.00093 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMD68796.1 - 0.0018 17.9 0.3 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EMD68796.1 - 0.0025 17.8 2.4 0.0061 16.5 0.1 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EMD68796.1 - 0.0026 17.3 0.5 0.029 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMD68796.1 - 0.0035 16.5 0.1 0.0078 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EMD68796.1 - 0.0052 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EMD68796.1 - 0.0054 16.6 0.1 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMD68796.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMD68796.1 - 0.014 14.8 0.2 0.23 10.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EMD68796.1 - 0.018 15.8 0.4 0.16 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMD68796.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMD68796.1 - 0.05 13.3 0.0 0.26 10.9 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EMD68796.1 - 0.065 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMD68796.1 - 0.078 12.6 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 EMD68796.1 - 0.093 12.1 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 Guanylate kinase AAA_28 PF13521.1 EMD68796.1 - 0.12 12.3 1.6 0.26 11.2 0.1 2.4 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 EMD68796.1 - 0.14 11.3 0.1 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EMD68796.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mito_carr PF00153.22 EMD68798.1 - 3.2e-68 225.4 1.8 1.1e-23 82.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2 PF00152.15 EMD68798.1 - 9.6e-51 172.5 0.0 1.4e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2263 PF10021.4 EMD68799.1 - 1.8e-34 118.8 0.0 3.3e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) COX6B PF02297.12 EMD68800.1 - 1.1e-23 82.9 6.1 1.4e-23 82.6 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EMD68800.1 - 0.14 12.2 2.9 0.6 10.1 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.4 EMD68801.1 - 5e-59 198.4 10.9 5.6e-59 198.2 7.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4407 PF14362.1 EMD68801.1 - 5.3 5.9 5.0 7.5 5.4 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_11 PF13414.1 EMD68802.1 - 6.3e-10 38.5 7.5 4.8e-06 26.1 0.7 4.5 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 EMD68802.1 - 1.5e-06 27.5 0.4 0.0033 16.9 0.5 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68802.1 - 5.4e-06 26.6 5.6 0.0075 16.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD68802.1 - 3.8e-05 23.7 0.3 0.31 11.1 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EMD68802.1 - 0.00021 20.9 8.8 0.011 15.6 0.5 6.1 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMD68802.1 - 0.00022 21.0 14.3 0.066 13.1 0.5 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD68802.1 - 0.0014 18.3 0.3 1.4 8.8 0.2 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD68802.1 - 0.0037 17.8 0.2 0.0037 17.8 0.1 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EMD68802.1 - 0.0068 16.6 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_17 PF13431.1 EMD68802.1 - 0.044 13.9 0.4 1 9.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMD68802.1 - 0.094 13.4 14.2 21 6.1 0.0 8.1 8 1 1 9 9 9 0 Tetratricopeptide repeat Daxx PF03344.10 EMD68802.1 - 2.1 6.7 15.3 3.8 5.8 10.6 1.3 1 0 0 1 1 1 0 Daxx Family NACHT PF05729.7 EMD68803.1 - 4.8e-10 39.3 0.0 1.6e-07 31.1 0.0 3.2 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EMD68803.1 - 1.3e-06 28.5 0.1 1.7e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD68803.1 - 5.8e-05 23.2 0.0 0.00076 19.6 0.0 2.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EMD68803.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Cullin PF00888.17 EMD68804.1 - 2.8e-32 112.0 0.0 5.2e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EMD68804.1 - 1.7e-08 34.6 0.0 6.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 ATP_bind_2 PF03668.10 EMD68804.1 - 0.13 11.3 0.3 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 P-loop ATPase protein family SMC_N PF02463.14 EMD68806.1 - 2.9e-28 98.6 0.0 5.3e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMD68806.1 - 8.3e-10 39.3 29.3 8.3e-10 39.3 20.3 5.7 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EMD68806.1 - 1.1e-08 35.4 3.7 1.9e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMD68806.1 - 5.2e-05 22.6 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EMD68806.1 - 0.00049 19.3 6.3 0.16 11.1 0.0 3.6 2 2 1 3 3 3 2 Reovirus sigma C capsid protein AAA_15 PF13175.1 EMD68806.1 - 0.00092 18.3 1.4 0.00092 18.3 1.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sel1 PF08238.7 EMD68807.1 - 1.6e-17 63.5 27.6 8.7e-06 26.2 0.1 7.0 7 1 0 7 7 7 5 Sel1 repeat TPR_14 PF13428.1 EMD68807.1 - 3.4 8.5 9.7 75 4.3 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD68807.1 - 8.2 6.2 7.8 3 7.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 EMD68808.1 - 1e-67 226.5 0.1 1.4e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EMD68808.1 - 2.7 5.8 22.7 3.3 5.5 15.7 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L11_N PF03946.9 EMD68809.1 - 4.9e-17 61.1 0.1 1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Fungal_trans PF04082.13 EMD68809.1 - 2.7e-15 55.9 0.0 4.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68809.1 - 1.7e-08 34.2 9.4 2.9e-08 33.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L11 PF00298.14 EMD68809.1 - 2e-07 31.0 0.3 3.8e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SHS2_FTSA PF02491.15 EMD68809.1 - 0.052 13.4 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Glyco_transf_8 PF01501.15 EMD68810.1 - 0.0021 17.4 0.3 0.0058 16.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_hydro_20 PF00728.17 EMD68811.1 - 1e-93 314.3 0.3 1.3e-93 314.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMD68811.1 - 1.9e-18 67.3 0.0 3.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMD68811.1 - 8.4e-05 23.1 0.4 0.00026 21.5 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Myf5 PF12232.3 EMD68812.1 - 0.069 13.7 1.3 0.069 13.7 0.9 2.0 2 0 0 2 2 2 0 Myogenic determination factor 5 HET PF06985.6 EMD68813.1 - 6.5e-21 74.9 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1767 PF08585.7 EMD68814.1 - 4.7e-19 68.4 0.0 7.3e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Rad52_Rad22 PF04098.10 EMD68814.1 - 0.13 12.0 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Rad52/22 family double-strand break repair protein Vps51 PF08700.6 EMD68815.1 - 8.6e-33 112.0 0.0 2e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EMD68815.1 - 0.0018 16.7 0.2 0.0023 16.4 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EMD68815.1 - 0.0019 18.1 0.2 0.0046 16.9 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 TPR_12 PF13424.1 EMD68816.1 - 6.4e-140 455.3 33.8 8.6e-21 73.6 0.1 8.0 3 1 7 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.1 EMD68816.1 - 1.3e-119 387.2 31.1 1.3e-12 47.2 0.1 11.8 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EMD68816.1 - 5.5e-46 150.7 32.7 0.00087 18.9 0.2 12.0 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 EMD68816.1 - 9.7e-42 140.4 12.0 5.4e-09 35.5 0.1 7.1 2 2 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 EMD68816.1 - 1e-39 132.5 37.6 0.00022 20.6 0.2 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMD68816.1 - 2.9e-29 98.5 40.2 0.008 16.0 0.3 11.9 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 EMD68816.1 - 2.2e-27 95.0 22.2 2.5e-06 27.9 0.3 7.7 4 1 4 9 9 8 7 Tetratricopeptide repeat HET PF06985.6 EMD68816.1 - 1e-22 80.7 10.4 1.7e-20 73.6 6.3 3.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_17 PF13431.1 EMD68816.1 - 7.8e-21 72.4 0.2 0.98 9.7 0.0 10.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD68816.1 - 4.7e-18 64.0 27.6 0.48 11.1 0.1 12.4 8 2 4 12 12 11 4 Tetratricopeptide repeat TPR_4 PF07721.9 EMD68816.1 - 5.7e-17 60.3 0.9 2 9.0 0.0 9.9 10 0 0 10 10 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD68816.1 - 8.6e-17 61.0 8.0 0.0045 17.0 0.1 6.4 1 1 6 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.17 EMD68816.1 - 2.6e-15 56.0 0.1 4.5e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Rab5-bind PF09311.6 EMD68816.1 - 1.8e-11 44.2 31.6 0.0044 16.9 1.5 5.9 1 1 6 7 7 7 7 Rabaptin-like protein DUF1925 PF09094.6 EMD68816.1 - 2.7e-11 43.2 13.5 8.9 6.3 0.0 9.7 5 1 3 9 9 9 0 Domain of unknown function (DUF1925) TPR_8 PF13181.1 EMD68816.1 - 9.2e-11 40.7 26.5 1.6 8.7 0.0 11.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD68816.1 - 2.1e-10 40.7 16.3 0.24 11.7 0.0 7.1 1 1 6 8 8 8 3 Tetratricopeptide repeat AAA_22 PF13401.1 EMD68816.1 - 1.6e-08 34.7 1.4 3.2e-08 33.7 0.1 2.3 2 1 1 3 3 1 1 AAA domain AAA_16 PF13191.1 EMD68816.1 - 3.5e-08 33.6 0.6 2e-07 31.1 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain FTCD PF02971.9 EMD68816.1 - 4.6e-07 29.5 1.2 18 4.9 0.0 7.5 2 2 6 8 8 8 0 Formiminotransferase domain nec1 PF10379.4 EMD68816.1 - 1.9e-06 27.2 0.0 1.1 8.4 0.0 6.0 1 1 6 7 7 7 1 Virulence protein nec1 Arch_ATPase PF01637.13 EMD68816.1 - 7.1e-06 25.8 0.0 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase Pilus_PilP PF11356.3 EMD68816.1 - 0.00013 22.1 2.0 13 6.0 0.0 5.9 7 0 0 7 7 6 0 Type IV pilus biogenesis NACHT PF05729.7 EMD68816.1 - 0.00017 21.2 0.2 0.0004 20.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 EMD68816.1 - 0.0018 17.7 0.2 0.0035 16.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EMD68816.1 - 0.0031 16.9 0.1 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMD68816.1 - 0.0067 16.6 0.0 0.044 13.9 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) TPR_6 PF13174.1 EMD68816.1 - 0.038 14.4 21.6 1.8e+02 2.8 0.0 10.4 10 0 0 10 10 10 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.7 EMD68818.1 - 2.2e-18 65.6 1.0 4.7e-18 64.5 0.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pan_kinase PF03309.9 EMD68818.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Type III pantothenate kinase Glyco_hydro_61 PF03443.9 EMD68819.1 - 1.7e-42 145.6 0.4 2.6e-42 145.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMD68819.1 - 5.3e-14 51.5 10.9 1.7e-13 49.9 7.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.11 EMD68820.1 - 2.1e-39 134.7 1.5 2.1e-39 134.7 1.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 CBM_4_9 PF02018.12 EMD68821.1 - 1.2 9.1 3.7 8.7 6.3 0.1 2.6 1 1 1 2 2 2 0 Carbohydrate binding domain Oxysterol_BP PF01237.13 EMD68823.1 - 6.6e-56 189.2 0.0 1.4e-55 188.2 0.0 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C2 PF00648.16 EMD68824.1 - 3.3e-21 75.5 0.0 5.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMD68824.1 - 5.3e-14 52.0 0.1 1.9e-12 47.0 0.0 3.0 2 2 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 EMD68824.1 - 4.5e-07 29.6 1.3 8.8e-07 28.7 0.9 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EMD68825.1 - 4.6e-54 180.1 1.2 2.8e-21 75.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.15 EMD68827.1 - 1.3e-171 571.2 0.1 1.6e-171 570.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF812 PF05667.6 EMD68828.1 - 0.00012 20.7 21.2 0.00012 20.7 14.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF812) CotH PF08757.6 EMD68828.1 - 0.0058 15.9 0.3 0.015 14.5 0.2 1.7 1 0 0 1 1 1 1 CotH protein FHA PF00498.21 EMD68829.1 - 8.9e-14 51.3 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EMD68830.1 - 3.3e-10 39.6 6.1 3.3e-10 39.6 4.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMD68830.1 - 4.5e-08 32.6 3.2 4.5e-08 32.6 2.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD68830.1 - 1.8e-06 27.9 5.1 7.3e-06 25.9 3.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD68830.1 - 3.1e-06 27.0 6.0 3.1e-06 27.0 4.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD68830.1 - 3.5e-06 26.5 4.5 3.5e-06 26.5 3.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD68830.1 - 0.0046 16.7 1.3 0.011 15.5 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMD68830.1 - 0.0052 16.4 4.7 0.03 14.0 2.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain RINGv PF12906.2 EMD68830.1 - 0.2 11.7 1.9 0.54 10.3 1.3 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EMD68830.1 - 0.63 9.6 2.7 1.4 8.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 EMD68830.1 - 1.4 8.5 5.0 1.3 8.6 2.4 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2410 PF10307.4 EMD68831.1 - 1.5e-77 259.4 0.0 2.1e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Glyoxalase_2 PF12681.2 EMD68834.1 - 1.2e-06 29.0 0.0 3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain EMG1 PF03587.9 EMD68835.1 - 2.5e-75 252.2 0.0 2.9e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LGT PF01790.13 EMD68836.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.0 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase OAD_gamma PF04277.8 EMD68836.1 - 0.04 14.3 0.4 0.054 13.8 0.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PMP22_Claudin PF00822.15 EMD68836.1 - 0.091 12.4 0.0 0.094 12.3 0.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family NAD_binding_6 PF08030.7 EMD68837.1 - 4.4e-32 111.1 0.0 7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMD68837.1 - 7.9e-20 70.6 0.1 2.1e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EMD68837.1 - 8.7e-16 58.1 18.4 9.2e-16 58.0 7.0 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMD68837.1 - 4.9e-05 23.3 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4131 PF13567.1 EMD68837.1 - 1.5 8.2 7.0 0.55 9.6 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Lactamase_B PF00753.22 EMD68838.1 - 7e-07 29.0 1.0 7e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD68838.1 - 5.1e-06 26.1 0.1 0.00022 20.8 0.1 2.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain DOR PF14839.1 EMD68839.1 - 0.0087 15.8 4.0 0.011 15.4 2.8 1.1 1 0 0 1 1 1 1 DOR family zf-CCHC PF00098.18 EMD68839.1 - 0.02 14.7 2.8 0.031 14.2 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle HemY_N PF07219.8 EMD68839.1 - 0.75 9.3 3.0 0.85 9.1 2.1 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Peptidase_C12 PF01088.16 EMD68840.1 - 9.7e-50 168.7 0.2 4.5e-48 163.2 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FAM60A PF15396.1 EMD68840.1 - 0.71 9.5 5.4 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 Protein Family FAM60A CRAL_TRIO PF00650.15 EMD68842.1 - 6.5e-24 84.2 0.0 9.7e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMD68842.1 - 1.3e-09 38.0 0.0 3.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain YccV-like PF08755.6 EMD68843.1 - 5.7e-26 90.3 0.1 1.3e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EMD68843.1 - 1.4e-15 57.1 0.0 3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EMD68843.1 - 4.6e-07 29.4 0.1 9.4e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD68843.1 - 3.3e-05 23.4 0.1 7.9e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EMD68843.1 - 0.0022 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sugar_tr PF00083.19 EMD68844.1 - 2.7e-123 411.8 24.7 3.1e-123 411.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68844.1 - 8.8e-20 70.7 34.7 3.2e-13 49.1 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Linker_histone PF00538.14 EMD68845.1 - 1.3e-20 73.2 0.1 3.1e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family TFIIF_alpha PF05793.7 EMD68845.1 - 6.8 4.9 41.0 8.7 4.5 28.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribonuclease_T2 PF00445.13 EMD68847.1 - 3.8e-46 157.1 0.6 3.8e-46 157.1 0.4 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family SHMT PF00464.14 EMD68848.1 - 3.8e-205 680.8 0.0 4.5e-205 680.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EMD68848.1 - 2.7e-06 26.6 0.0 6.6e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMD68848.1 - 6.1e-05 21.9 0.0 9.3e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMD68848.1 - 0.0011 18.2 0.0 0.0025 17.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.5 EMD68848.1 - 0.17 11.6 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Fig1 PF12351.3 EMD68849.1 - 3e-58 196.7 4.2 3e-58 196.7 2.9 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EMD68849.1 - 1.6e-11 44.2 7.4 2.1e-11 43.7 5.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EMD68849.1 - 0.0023 16.8 4.5 0.0023 16.8 3.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) MLTD_N PF06474.7 EMD68849.1 - 0.62 10.2 4.9 0.77 9.9 1.8 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF202 PF02656.10 EMD68849.1 - 3.2 8.0 12.7 1.4 9.1 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PGG PF13962.1 EMD68849.1 - 3.9 7.1 7.5 0.51 9.9 1.7 2.2 2 1 0 2 2 2 0 Domain of unknown function HSP9_HSP12 PF04119.7 EMD68850.1 - 2.2e-18 66.0 7.6 2.2e-18 66.0 5.3 1.4 2 0 0 2 2 2 1 Heat shock protein 9/12 DEAD PF00270.24 EMD68851.1 - 3.7e-22 78.5 0.1 7.3e-21 74.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD68851.1 - 1.4e-19 69.6 0.1 1.5e-18 66.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 EMD68851.1 - 1e-13 50.8 0.1 2.3e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EMD68851.1 - 7.5e-10 38.3 0.1 1.9e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Pyridoxal_deC PF00282.14 EMD68852.1 - 2.9e-31 108.2 0.0 4.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMD68852.1 - 0.00053 19.2 0.0 0.0012 18.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SMC_N PF02463.14 EMD68854.1 - 1.7e-73 246.5 19.4 3.8e-73 245.3 13.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMD68854.1 - 2.2e-29 101.8 0.2 6.2e-28 97.1 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMD68854.1 - 7.9e-11 42.4 11.9 2.3e-05 24.5 0.3 3.5 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMD68854.1 - 0.00058 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EMD68854.1 - 0.00083 18.6 27.5 0.0021 17.3 1.1 6.1 4 2 3 7 7 7 3 Reovirus sigma C capsid protein IncA PF04156.9 EMD68854.1 - 0.0016 18.0 123.7 0.0072 15.9 7.6 7.9 3 2 4 7 7 7 3 IncA protein Tropomyosin_1 PF12718.2 EMD68854.1 - 0.0027 17.5 13.0 0.0027 17.5 9.0 8.3 3 2 4 7 7 6 1 Tropomyosin like Bacillus_HBL PF05791.6 EMD68854.1 - 0.0039 16.5 2.1 0.0039 16.5 1.4 6.9 4 2 4 9 9 9 2 Bacillus haemolytic enterotoxin (HBL) Tropomyosin PF00261.15 EMD68854.1 - 0.0046 16.0 17.8 0.0046 16.0 12.4 6.4 4 1 1 6 6 5 1 Tropomyosin GAS PF13851.1 EMD68854.1 - 0.0084 15.3 113.0 0.0093 15.1 5.2 7.4 5 2 2 7 7 7 4 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EMD68854.1 - 0.0094 15.4 0.5 0.0094 15.4 0.3 11.6 5 3 6 12 12 12 1 Septum formation initiator AAA_13 PF13166.1 EMD68854.1 - 0.025 13.0 100.4 0.023 13.1 19.4 6.2 4 2 2 6 6 6 0 AAA domain DUF869 PF05911.6 EMD68854.1 - 0.099 10.8 97.6 0.029 12.6 28.0 3.1 2 1 0 3 3 3 0 Plant protein of unknown function (DUF869) DUF3591 PF12157.3 EMD68855.1 - 2.3e-187 622.9 0.1 2.3e-187 622.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EMD68855.1 - 0.0081 15.8 1.3 0.023 14.3 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMD68855.1 - 0.024 14.5 0.8 0.041 13.8 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.5 EMD68856.1 - 2.8e-50 170.0 0.0 3.4e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EMD68856.1 - 1.1e-09 38.1 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMD68856.1 - 3.4e-09 36.7 0.0 5.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMD68856.1 - 6.3e-09 35.6 0.0 9.7e-09 35.0 0.0 1.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EMD68856.1 - 3e-07 29.9 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EMD68856.1 - 7.7e-06 26.4 0.0 1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EMD68856.1 - 0.00054 19.1 0.0 0.00075 18.6 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase MTS PF05175.9 EMD68856.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMD68856.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.12 EMD68856.1 - 0.092 11.8 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_5 PF01795.14 EMD68856.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family PrmA PF06325.8 EMD68856.1 - 0.096 11.7 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GRASP55_65 PF04495.9 EMD68857.1 - 1.4e-48 164.4 0.0 2.3e-46 157.2 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Lactamase_B_3 PF13483.1 EMD68860.1 - 1.8e-08 34.2 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PIP5K PF01504.13 EMD68861.1 - 3.2e-86 288.5 0.3 3.2e-86 288.5 0.2 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA PF00004.24 EMD68863.1 - 1.7e-45 154.4 0.1 5.4e-45 152.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD68863.1 - 4.9e-09 36.0 0.1 1.6e-08 34.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMD68863.1 - 5.5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMD68863.1 - 5e-07 29.8 0.0 2e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD68863.1 - 1e-06 28.8 0.7 0.0003 20.9 0.5 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMD68863.1 - 5.6e-06 25.4 0.2 1.2e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMD68863.1 - 0.00021 21.2 0.0 0.00076 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD68863.1 - 0.00044 19.3 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EMD68863.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD68863.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EMD68863.1 - 0.00079 20.2 0.0 0.0051 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD68863.1 - 0.0013 18.4 0.1 0.056 13.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EMD68863.1 - 0.0014 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EMD68863.1 - 0.0018 17.0 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EMD68863.1 - 0.0024 17.5 0.0 0.0083 15.8 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_11 PF13086.1 EMD68863.1 - 0.0034 16.9 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD68863.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMD68863.1 - 0.0038 16.3 0.1 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EMD68863.1 - 0.0045 16.5 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EMD68863.1 - 0.0049 16.5 0.0 0.037 13.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EMD68863.1 - 0.0063 16.2 0.5 0.079 12.6 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 EMD68863.1 - 0.0072 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EMD68863.1 - 0.0076 16.5 0.9 0.82 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMD68863.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMD68863.1 - 0.013 14.9 0.3 0.03 13.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMD68863.1 - 0.013 14.8 1.8 0.084 12.2 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 EMD68863.1 - 0.014 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD68863.1 - 0.017 15.4 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMD68863.1 - 0.021 13.9 1.3 0.46 9.5 0.0 2.7 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 EMD68863.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_Hsp90 PF03225.9 EMD68863.1 - 0.042 12.1 0.0 0.067 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activat PF00158.21 EMD68863.1 - 0.046 13.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EMD68863.1 - 0.092 12.7 0.1 0.51 10.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMD68863.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EMD68863.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.16 EMD68865.1 - 1.5e-13 50.3 0.2 1.5e-13 50.3 0.1 3.2 2 1 0 2 2 2 1 ARID/BRIGHT DNA binding domain Caldesmon PF02029.10 EMD68865.1 - 2.5e-09 36.1 10.5 3.1e-09 35.8 7.3 1.3 1 0 0 1 1 1 1 Caldesmon LMBR1 PF04791.11 EMD68865.1 - 0.027 13.0 9.3 0.04 12.5 6.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Abhydrolase_2 PF02230.11 EMD68866.1 - 4.4e-24 85.1 0.0 1.9e-21 76.5 0.0 2.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMD68866.1 - 2.8e-05 23.8 0.0 4.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD68866.1 - 0.00037 20.4 0.3 0.031 14.1 0.3 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family SynMuv_product PF06047.6 EMD68866.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Ras-induced vulval development antagonist zf-HIT PF04438.11 EMD68867.1 - 1.4e-08 34.2 4.2 2.1e-08 33.6 2.9 1.3 1 0 0 1 1 1 1 HIT zinc finger KRE9 PF05390.6 EMD68867.1 - 0.025 14.9 0.9 0.053 13.8 0.1 1.9 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Antimicrobial10 PF08105.6 EMD68867.1 - 0.1 12.2 0.3 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 Metchnikowin family zf-ribbon_3 PF13248.1 EMD68867.1 - 0.55 9.5 3.9 6.8 6.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rhomboid PF01694.17 EMD68869.1 - 3.1e-12 46.7 7.7 3.1e-12 46.7 5.3 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EMD68870.1 - 5.7e-94 315.6 20.1 1.6e-89 300.9 0.0 3.1 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component DUF1176 PF06674.6 EMD68870.1 - 0.07 12.2 2.3 0.11 11.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Peptidase_M28 PF04389.12 EMD68870.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 PCI PF01399.22 EMD68871.1 - 1.8e-08 34.6 0.2 5.6e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain Apc5 PF12862.2 EMD68871.1 - 0.029 14.2 2.9 0.046 13.5 0.8 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Spo0A_C PF08769.6 EMD68871.1 - 0.046 13.5 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal NAD_binding_10 PF13460.1 EMD68872.1 - 1e-18 68.0 0.0 1.4e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD68872.1 - 1.1e-14 54.3 0.1 2.1e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMD68872.1 - 3.2e-14 52.7 0.0 3.9e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMD68872.1 - 3.7e-12 45.5 0.0 6.6e-12 44.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMD68872.1 - 2.4e-08 33.2 0.0 1.3e-06 27.5 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMD68872.1 - 1.1e-06 27.7 1.5 0.0001 21.3 0.1 3.2 2 1 1 3 3 3 1 Male sterility protein KR PF08659.5 EMD68872.1 - 0.00087 19.0 0.0 0.76 9.4 0.0 2.4 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 EMD68872.1 - 0.0015 18.4 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EMD68872.1 - 0.0038 16.2 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMD68872.1 - 0.023 13.5 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_synthase PF02540.12 EMD68872.1 - 0.1 11.4 0.1 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 NAD synthase DUF155 PF02582.9 EMD68873.1 - 3.1e-43 147.7 0.0 4.6e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 EMD68873.1 - 0.0049 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMD68873.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin HATPase_c_2 PF13581.1 EMD68873.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Methyltransf_9 PF08003.6 EMD68873.1 - 0.14 10.8 0.1 0.62 8.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Clathrin PF00637.15 EMD68874.1 - 2.4e-17 62.8 0.2 5.9e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_5 PF14634.1 EMD68874.1 - 0.021 14.5 0.8 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.27 EMD68874.1 - 0.054 13.4 2.0 4.6 7.2 0.0 3.7 3 1 0 3 3 3 0 WD domain, G-beta repeat zf-rbx1 PF12678.2 EMD68874.1 - 0.076 13.1 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EMD68874.1 - 0.23 11.3 3.5 0.71 9.7 2.4 1.9 1 1 0 1 1 1 0 Ring finger domain ECH PF00378.15 EMD68875.1 - 1.2e-45 155.5 0.0 1.5e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HIT PF01230.18 EMD68876.1 - 1.2e-23 83.4 0.4 1.8e-23 82.9 0.3 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMD68876.1 - 7.4e-14 51.9 0.2 9.9e-14 51.5 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EMD68876.1 - 3.4e-05 23.4 0.1 4.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 N6-adenineMlase PF10237.4 EMD68877.1 - 1.3e-57 193.9 0.0 1.6e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EMD68877.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EMD68877.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMD68877.1 - 0.023 14.7 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.22 EMD68878.1 - 2.9e-22 79.2 0.2 4e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD68878.1 - 5.1e-06 26.1 0.2 7.2e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 EMD68879.1 - 7.1e-123 410.5 24.1 9.2e-123 410.1 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD68879.1 - 4.2e-28 98.0 55.9 1.4e-24 86.4 22.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD68879.1 - 0.00023 19.5 11.6 0.00046 18.5 3.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMD68879.1 - 1.4 8.7 13.3 1.2 8.9 0.2 3.5 3 1 0 3 3 3 0 MFS_1 like family Zn_clus PF00172.13 EMD68880.1 - 4.5e-06 26.4 13.3 8.8e-06 25.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Img2 PF05046.9 EMD68881.1 - 2.1e-24 85.5 0.1 3e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EMD68881.1 - 0.0088 15.8 0.1 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 Translation initiation factor SUI1 eIF3_N PF09440.5 EMD68882.1 - 1.6e-44 151.3 5.1 3.7e-44 150.1 3.5 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EMD68882.1 - 4.5e-15 55.8 1.2 9e-15 54.8 0.0 2.1 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EMD68882.1 - 0.012 15.4 0.2 0.085 12.6 0.0 2.3 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 XhlA PF10779.4 EMD68882.1 - 0.033 14.1 0.4 0.44 10.4 0.0 2.9 3 0 0 3 3 3 0 Haemolysin XhlA RPN7 PF10602.4 EMD68882.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Frag1 PF10277.4 EMD68883.1 - 2.2e-40 138.4 10.1 2.2e-40 138.4 7.0 2.9 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EMD68883.1 - 0.0001 22.3 0.0 0.00027 20.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.6 EMD68884.1 - 4.5e-26 90.4 2.5 1.1e-25 89.2 1.7 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EMD68884.1 - 0.016 15.8 2.5 5.6 7.8 0.0 4.5 2 2 4 6 6 6 0 Tetratricopeptide repeat RF-1 PF00472.15 EMD68885.1 - 9.1e-14 51.2 0.3 1.4e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain M20_dimer PF07687.9 EMD68885.1 - 0.077 12.7 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase dimerisation domain RRM_1 PF00076.17 EMD68886.1 - 7.7e-08 31.8 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD68886.1 - 1.2e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMD68886.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.1 EMD68886.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.8 EMD68888.1 - 1.5e-10 40.6 0.8 6.1e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF2013 PF09431.5 EMD68889.1 - 1.2e-46 157.9 0.7 1.2e-46 157.9 0.5 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2013) MFS_1 PF07690.11 EMD68890.1 - 6.1e-31 107.4 29.4 1.4e-25 89.8 20.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3176 PF11374.3 EMD68892.1 - 1e-20 73.6 1.5 6.6e-19 67.8 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3176) ubiquitin PF00240.18 EMD68894.1 - 1.4e-10 40.4 0.0 3.3e-10 39.2 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin family zf-AN1 PF01428.11 EMD68894.1 - 5.8e-09 35.6 14.0 8.9e-09 35.0 9.7 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Telomere_Sde2 PF13019.1 EMD68894.1 - 0.00024 20.8 0.2 0.00038 20.1 0.1 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD PF11976.3 EMD68894.1 - 0.00038 20.0 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMD68894.1 - 0.0092 16.1 0.1 0.012 15.8 0.1 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Acyl-CoA_dh_1 PF00441.19 EMD68895.1 - 3.6e-34 118.0 0.7 6.1e-34 117.2 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EMD68895.1 - 9.9e-20 70.1 0.1 3.1e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EMD68895.1 - 2.5e-18 65.3 0.8 5.4e-18 64.2 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMD68895.1 - 3.2e-06 27.6 0.3 9.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD68895.1 - 4.1e-06 27.0 0.0 9.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Gag_p19 PF02228.11 EMD68896.1 - 0.013 15.7 0.3 0.02 15.1 0.2 1.3 1 0 0 1 1 1 0 Major core protein p19 HEAT PF02985.17 EMD68898.1 - 1.5e-22 77.5 11.0 0.00011 21.9 0.0 11.3 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 EMD68898.1 - 3.1e-18 65.8 7.0 7e-10 39.0 0.1 8.6 5 3 5 10 10 10 3 HEAT repeats HEAT_EZ PF13513.1 EMD68898.1 - 4.2e-17 62.0 22.6 2.1e-09 37.6 0.4 10.3 8 3 4 12 12 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMD68898.1 - 5e-10 39.6 0.2 0.013 15.9 0.0 5.9 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMD68898.1 - 1.9e-06 27.3 0.4 0.011 15.1 0.1 4.2 4 1 0 4 4 4 2 CLASP N terminal MMS19_C PF12460.3 EMD68898.1 - 2.9e-06 26.2 4.2 0.00012 20.9 0.4 4.1 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EMD68898.1 - 3.2e-06 26.9 0.2 0.072 12.7 0.0 4.5 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis DUF4042 PF13251.1 EMD68898.1 - 0.00074 19.0 0.7 4.7 6.6 0.0 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.2 EMD68898.1 - 0.0011 18.8 0.0 0.44 10.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EMD68898.1 - 0.0056 16.5 2.3 0.67 9.7 0.0 4.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EMD68898.1 - 0.0061 14.8 0.1 0.049 11.9 0.0 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit IBN_N PF03810.14 EMD68898.1 - 0.033 14.0 0.2 0.12 12.3 0.1 2.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF3385 PF11865.3 EMD68898.1 - 0.055 13.4 0.0 28 4.6 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) V-ATPase_H_N PF03224.9 EMD68898.1 - 0.18 10.8 3.9 0.83 8.7 0.0 3.2 3 1 0 3 3 3 0 V-ATPase subunit H DRIM PF07539.7 EMD68898.1 - 0.22 10.9 1.9 0.49 9.8 0.3 2.5 2 1 1 3 3 3 0 Down-regulated in metastasis Arm PF00514.18 EMD68898.1 - 1.8 8.5 10.1 17 5.4 0.0 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CBS PF00571.23 EMD68899.1 - 1.4e-40 136.8 8.2 4.1e-11 42.4 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EMD68899.1 - 1.7e-09 37.2 0.0 5e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 PB1 domain DUF3235 PF11574.3 EMD68899.1 - 0.088 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Ribosomal_S26e PF01283.14 EMD68900.1 - 7.8e-51 171.1 8.3 9.4e-51 170.8 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EMD68900.1 - 0.039 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 EMD68900.1 - 0.04 14.2 0.1 8.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EMD68900.1 - 0.053 13.9 0.7 1.7 9.1 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain VanZ PF04892.7 EMD68901.1 - 9.4e-12 45.0 0.3 1.2e-11 44.6 0.2 1.2 1 0 0 1 1 1 1 VanZ like family Herpes_LMP1 PF05297.6 EMD68901.1 - 0.88 8.4 2.5 0.33 9.8 0.1 1.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Bromodomain PF00439.20 EMD68902.1 - 1.6e-22 79.2 1.4 7.3e-22 77.0 0.6 2.3 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EMD68902.1 - 2.9e-06 26.9 0.1 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated CASP_C PF08172.7 EMD68902.1 - 0.069 12.1 4.5 0.22 10.4 3.1 1.9 1 0 0 1 1 1 0 CASP C terminal AT_hook PF02178.14 EMD68903.1 - 5.3 7.0 21.0 4.9 7.1 5.8 4.3 3 1 0 3 3 3 0 AT hook motif Rhomboid PF01694.17 EMD68904.1 - 4e-13 49.6 9.8 4e-13 49.6 6.8 1.4 2 0 0 2 2 2 1 Rhomboid family Lysis_S PF04971.7 EMD68904.1 - 0.0026 17.4 1.2 0.41 10.3 0.0 2.4 2 0 0 2 2 2 2 Lysis protein S RseC_MucC PF04246.7 EMD68904.1 - 0.39 10.2 2.5 8.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DEAD PF00270.24 EMD68905.1 - 1.2e-41 142.0 0.0 1.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD68905.1 - 8e-24 83.3 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain COX14 PF14880.1 EMD68905.1 - 0.21 11.2 0.1 0.42 10.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly COG5 PF10392.4 EMD68906.1 - 1.3e-42 144.8 3.9 7.8e-42 142.3 0.1 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 MutS_III PF05192.13 EMD68906.1 - 0.00055 19.7 1.8 0.0024 17.6 0.1 2.2 2 1 0 2 2 2 1 MutS domain III AAA PF00004.24 EMD68907.1 - 1.6e-42 144.8 0.0 2.7e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMD68907.1 - 1.7e-28 98.3 0.0 1.3e-27 95.4 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EMD68907.1 - 1.2e-21 76.2 4.4 1.2e-21 76.2 3.1 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EMD68907.1 - 3.4e-06 27.8 0.1 2.1e-05 25.3 0.0 2.4 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EMD68907.1 - 1.4e-05 24.2 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMD68907.1 - 2e-05 24.3 0.0 0.00012 21.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMD68907.1 - 3.1e-05 23.4 0.0 6.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EMD68907.1 - 3.5e-05 23.9 0.1 0.0019 18.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMD68907.1 - 5e-05 23.4 0.0 0.0096 16.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EMD68907.1 - 6.1e-05 22.9 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMD68907.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD68907.1 - 0.00014 21.9 0.0 0.00066 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EMD68907.1 - 0.00017 20.4 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EMD68907.1 - 0.0003 19.8 0.0 0.0015 17.5 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EMD68907.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMD68907.1 - 0.00056 19.3 0.1 0.2 11.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD68907.1 - 0.0055 17.0 0.2 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMD68907.1 - 0.009 15.6 0.5 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMD68907.1 - 0.016 14.2 0.0 0.16 11.0 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EMD68907.1 - 0.019 14.6 0.1 0.31 10.6 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 EMD68907.1 - 0.019 14.1 0.2 0.062 12.4 0.0 1.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMD68907.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EMD68907.1 - 0.035 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin USP8_dimer PF08969.6 EMD68907.1 - 0.041 13.8 3.3 0.079 12.9 2.3 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain PhoH PF02562.11 EMD68907.1 - 0.044 13.0 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EMD68907.1 - 0.046 13.1 0.0 0.18 11.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMD68907.1 - 0.052 12.4 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EMD68907.1 - 0.065 12.8 0.0 0.48 10.0 0.0 2.1 1 1 0 1 1 1 0 NACHT domain ResIII PF04851.10 EMD68907.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_21 PF13304.1 EMD68907.1 - 0.12 12.2 0.5 2.8 7.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF4398 PF14346.1 EMD68907.1 - 1.5 8.8 5.4 0.93 9.5 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Prefoldin_2 PF01920.15 EMD68908.1 - 2.4e-17 62.6 6.0 2.9e-17 62.3 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.6 EMD68908.1 - 0.002 17.7 2.5 0.0024 17.5 1.7 1.1 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Mnd1 PF03962.10 EMD68908.1 - 0.0064 16.1 3.4 0.0067 16.1 2.4 1.0 1 0 0 1 1 1 1 Mnd1 family PAXIP1_C PF15364.1 EMD68908.1 - 0.02 14.7 0.4 0.023 14.6 0.3 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein FTA4 PF13093.1 EMD68908.1 - 0.082 12.3 2.2 0.095 12.1 1.5 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2968 PF11180.3 EMD68908.1 - 0.12 11.8 2.7 0.14 11.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EMD68908.1 - 0.25 10.8 9.6 0.18 11.2 1.6 2.2 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EMD68908.1 - 0.42 10.8 3.5 0.71 10.1 2.4 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMD68908.1 - 2.5 7.6 7.5 3.3 7.2 5.2 1.3 1 1 0 1 1 1 0 IncA protein M PF02370.11 EMD68908.1 - 7.3 7.3 9.4 20 5.9 0.8 2.8 2 0 0 2 2 2 0 M protein repeat SAM_2 PF07647.12 EMD68909.1 - 9.3e-09 35.0 0.1 2.3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMD68909.1 - 9.5e-07 28.8 1.2 1.9e-06 27.9 0.2 2.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Fungal_trans PF04082.13 EMD68910.1 - 2.6e-14 52.7 0.2 4.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1258 PF06869.7 EMD68910.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) MFS_1 PF07690.11 EMD68911.1 - 7.7e-35 120.2 22.3 7.7e-35 120.2 15.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EMD68912.1 - 1.8e-06 28.1 0.1 1.9e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) QRPTase_C PF01729.14 EMD68914.1 - 3.2e-54 182.9 0.1 3.9e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EMD68914.1 - 3.2e-25 87.7 0.1 1e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1341 PF07071.6 EMD68914.1 - 0.13 11.7 1.3 5.2 6.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1341) Adenylsucc_synt PF00709.16 EMD68916.1 - 2.9e-161 536.8 0.0 3.6e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase MFS_1 PF07690.11 EMD68916.1 - 1e-32 113.2 31.8 1.8e-32 112.4 22.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.6 EMD68916.1 - 0.017 14.5 0.3 0.093 12.2 0.2 2.2 1 0 0 1 1 1 0 ATPase proteolipid family PBP PF01161.15 EMD68917.1 - 2.3e-17 63.2 0.3 2.9e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPP_enzyme_N PF02776.13 EMD68918.1 - 4.6e-34 117.3 0.0 8.2e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMD68918.1 - 3.1e-24 85.3 0.0 6.3e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMD68918.1 - 3.6e-12 46.0 0.0 7.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Vpu PF00558.14 EMD68919.1 - 0.74 9.4 4.3 1.5 8.4 3.0 1.4 1 0 0 1 1 1 0 Vpu protein Pkinase PF00069.20 EMD68920.1 - 1.7e-65 220.7 0.0 2.7e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD68920.1 - 1.2e-45 155.6 0.0 2e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD68920.1 - 4e-09 35.8 0.0 8.1e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMD68920.1 - 0.041 12.9 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LacY_symp PF01306.14 EMD68921.1 - 1.5e-05 23.7 1.0 1.6e-05 23.6 0.7 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter TspO_MBR PF03073.10 EMD68921.1 - 0.085 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 TspO/MBR family Tyrosinase PF00264.15 EMD68922.1 - 3.8e-46 158.0 0.0 1.2e-45 156.3 0.0 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase zf-H2C2 PF09337.5 EMD68923.1 - 2.9e-21 74.5 3.9 4.8e-21 73.8 2.7 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EMD68923.1 - 0.00065 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMD68923.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMD68923.1 - 0.086 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAT1 PF09770.4 EMD68923.1 - 0.48 8.5 14.7 0.55 8.3 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mog1 PF04603.7 EMD68924.1 - 2e-21 76.3 0.0 1.9e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Ran-interacting Mog1 protein zf-C2H2_jaz PF12171.3 EMD68925.1 - 8e-09 35.3 2.6 1.9e-08 34.1 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EMD68925.1 - 0.00064 19.2 0.3 0.0015 18.0 0.2 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.2 EMD68925.1 - 0.0037 17.4 0.7 0.007 16.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMD68925.1 - 0.072 13.4 0.2 0.17 12.3 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Aconitase PF00330.15 EMD68926.1 - 3e-178 593.0 0.0 5.7e-178 592.1 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMD68926.1 - 3.4e-47 159.8 0.0 5.6e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SprT-like PF10263.4 EMD68927.1 - 4.8e-50 169.2 2.7 8e-50 168.5 1.9 1.4 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EMD68927.1 - 0.0093 15.8 1.4 0.026 14.4 1.0 1.7 1 0 0 1 1 1 1 Zinc ribbon domain RNase_T PF00929.19 EMD68928.1 - 6.1e-13 49.3 0.2 4.1e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Exonuclease DUF842 PF05811.8 EMD68928.1 - 0.0098 15.3 2.8 0.024 14.1 1.9 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DNA_pol_A_exo1 PF01612.15 EMD68928.1 - 0.036 13.5 0.2 0.18 11.2 0.1 2.2 1 1 0 1 1 1 0 3'-5' exonuclease Pyr_redox_3 PF13738.1 EMD68929.1 - 2.2e-14 53.9 0.0 3.8e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD68929.1 - 1.2e-12 46.8 0.0 5.5e-09 34.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD68929.1 - 4.8e-10 38.8 0.1 7.7e-09 34.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD68929.1 - 7e-07 29.3 0.0 1.4e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD68929.1 - 3.9e-05 23.5 0.0 0.00031 20.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD68929.1 - 3.9e-05 22.7 0.1 0.12 11.2 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMD68929.1 - 0.0035 16.2 0.1 2.8 6.6 0.0 2.6 2 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.12 EMD68929.1 - 0.0073 15.4 0.0 0.034 13.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EMD68929.1 - 0.0087 15.8 0.3 1.4 8.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD68929.1 - 0.23 9.8 0.3 15 3.9 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Ureidogly_hydro PF04115.7 EMD68930.1 - 2.9e-60 202.3 0.0 3.4e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase eIF2A PF08662.6 EMD68931.1 - 8e-81 270.3 0.1 3.8e-80 268.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EMD68931.1 - 1.1e-06 28.3 0.6 0.36 10.7 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat CDV3 PF15359.1 EMD68931.1 - 0.0053 16.8 0.4 0.0053 16.8 0.3 2.6 3 1 0 3 3 3 1 Carnitine deficiency-associated protein 3 DPPIV_N PF00930.16 EMD68931.1 - 0.035 12.7 0.0 1.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region KGG PF10685.4 EMD68932.1 - 9.6e-18 63.6 8.0 1.3e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Mago-bind PF09282.5 EMD68932.1 - 0.38 10.3 2.4 1.5 8.4 0.2 2.1 2 0 0 2 2 2 0 Mago binding PsbI PF02532.9 EMD68932.1 - 1 9.0 4.7 15 5.3 0.8 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) UDG PF03167.14 EMD68933.1 - 1.8e-25 89.2 0.0 2.7e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ThuA PF06283.6 EMD68934.1 - 5.9e-51 173.2 0.2 6.7e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 EMD68934.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1355) p450 PF00067.17 EMD68935.1 - 7.1e-62 209.4 0.0 1e-61 208.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2839 PF10999.3 EMD68935.1 - 0.13 12.3 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) BLOC1_2 PF10046.4 EMD68936.1 - 0.07 13.2 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 peroxidase PF00141.18 EMD68937.1 - 4.6e-32 111.3 0.1 5.9e-32 111.0 0.1 1.2 1 0 0 1 1 1 1 Peroxidase DUF1326 PF07040.6 EMD68937.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Fungal_trans_2 PF11951.3 EMD68938.1 - 1.1e-32 113.1 0.2 1.4e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68938.1 - 3.1e-06 26.9 12.6 3.1e-06 26.9 8.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_45 PF02015.11 EMD68939.1 - 8.1e-75 251.2 15.8 9.3e-75 251.1 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 WLM PF08325.5 EMD68940.1 - 1.3e-45 155.5 0.1 3.4e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EMD68940.1 - 4.9e-10 39.5 0.3 1e-09 38.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 EMD68940.1 - 0.046 13.5 6.4 0.12 12.2 4.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EMD68940.1 - 0.095 12.0 3.0 0.63 9.4 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RanBP PF00641.13 EMD68940.1 - 0.096 11.8 7.6 0.11 11.6 0.4 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 EMD68940.1 - 0.86 9.6 3.6 2.3 8.3 2.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PACT_coil_coil PF10495.4 EMD68941.1 - 4.8e-05 23.2 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF4231 PF14015.1 EMD68941.1 - 0.0028 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Myc-LZ PF02344.10 EMD68941.1 - 0.0034 16.9 0.8 0.0064 16.0 0.6 1.5 1 0 0 1 1 1 1 Myc leucine zipper domain SSP160 PF06933.6 EMD68941.1 - 0.0085 14.1 0.3 0.0088 14.0 0.2 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 SGT1 PF07093.6 EMD68942.1 - 2.5e-128 429.0 24.7 3.1e-126 422.1 17.1 2.0 1 1 0 1 1 1 1 SGT1 protein LRR_4 PF12799.2 EMD68943.1 - 0.008 15.7 1.8 0.53 9.9 0.0 3.7 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD68943.1 - 0.014 15.1 2.6 1.1 9.0 0.1 3.7 4 1 0 4 4 4 0 Leucine rich repeat DUF1727 PF08353.5 EMD68943.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) LRR_6 PF13516.1 EMD68943.1 - 0.19 11.9 3.1 1.4 9.1 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 EMD68943.1 - 0.24 11.5 0.1 0.24 11.5 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EMD68943.1 - 0.26 11.6 1.7 2.4 8.7 0.0 3.2 2 1 0 2 2 2 0 Leucine rich repeat Kinesin PF00225.18 EMD68945.1 - 9.1e-111 369.7 0.3 2.2e-110 368.5 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain zf-CCHC PF00098.18 EMD68947.1 - 4e-08 32.8 16.2 1.1e-05 25.0 1.4 4.2 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMD68947.1 - 0.014 15.0 5.4 1.1 9.0 0.7 2.7 2 0 0 2 2 2 0 Zinc knuckle MSA_2 PF00985.12 EMD68947.1 - 0.2 11.7 2.3 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family RVP_2 PF08284.6 EMD68948.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Lactamase_B_2 PF12706.2 EMD68950.1 - 3.3e-22 78.9 0.6 4.4e-22 78.5 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMD68950.1 - 1.2e-13 51.1 1.0 2.5e-13 50.0 0.7 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMD68950.1 - 0.005 16.5 5.4 0.027 14.1 2.4 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Peptidase_M7 PF02031.11 EMD68951.1 - 0.058 13.1 0.2 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Cytomega_UL84 PF06284.6 EMD68951.1 - 0.12 10.7 1.1 0.2 10.0 0.1 1.7 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein DDE_1 PF03184.14 EMD68952.1 - 1.6e-14 53.6 0.0 1.7e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2583 PF10762.4 EMD68954.1 - 0.051 13.7 0.2 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) GlgS PF08971.6 EMD68954.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycogen synthesis protein DUF202 PF02656.10 EMD68954.1 - 3.7 7.8 0.0 3.7 7.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Borrelia_P13 PF05628.7 EMD68955.1 - 0.063 13.0 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Borrelia membrane protein P13 DUF1270 PF06900.6 EMD68955.1 - 3 8.0 5.8 2.1 8.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) BTV_NS2 PF04514.7 EMD68956.1 - 0.75 8.6 11.1 0.83 8.4 7.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 OHCU_decarbox PF09349.5 EMD68956.1 - 0.84 9.9 9.4 0.86 9.8 5.4 1.9 1 1 1 2 2 2 0 OHCU decarboxylase Tannase PF07519.6 EMD68957.1 - 5.9e-101 338.5 0.9 7.3e-101 338.2 0.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Glyco_hydro_61 PF03443.9 EMD68959.1 - 1.2e-30 107.0 0.1 1.5e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_5 PF12695.2 EMD68960.1 - 0.00033 20.4 0.1 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD68960.1 - 0.0012 18.2 0.1 0.0044 16.4 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EMD68960.1 - 0.0023 17.2 0.2 0.0058 15.9 0.1 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMD68960.1 - 0.0034 16.6 0.1 0.0071 15.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMD68960.1 - 0.053 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMD68960.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 EMD68962.1 - 5.8e-39 133.8 0.0 1.7e-38 132.3 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Arginase PF00491.16 EMD68963.1 - 2.3e-88 296.1 0.0 2.6e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.3 EMD68964.1 - 8.3e-47 159.5 1.6 1.1e-46 159.1 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68964.1 - 3.2e-09 36.5 6.6 9.1e-09 35.0 4.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 EMD68965.1 - 8.3e-18 64.2 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 EMD68965.1 - 0.012 13.6 0.0 0.018 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 EMD68965.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Na_Ca_ex PF01699.19 EMD68966.1 - 2.6e-27 95.1 25.0 1.5e-14 53.7 3.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FixQ PF05545.6 EMD68966.1 - 0.73 9.5 0.1 0.73 9.5 0.0 3.8 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ CN_hydrolase PF00795.17 EMD68967.1 - 9.9e-32 109.7 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dehydratase_hem PF13816.1 EMD68968.1 - 4.4e-83 278.8 0.2 5e-83 278.7 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Sdh_cyt PF01127.17 EMD68969.1 - 8.6e-23 80.4 4.6 1.1e-22 80.1 3.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit p450 PF00067.17 EMD68971.1 - 1.3e-19 70.0 0.0 1.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1800 PF08811.6 EMD68971.1 - 0.00058 18.8 0.3 0.00085 18.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) NmrA PF05368.8 EMD68972.1 - 3.1e-22 78.9 0.1 4e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD68972.1 - 1.2e-10 41.6 0.1 2.4e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD68972.1 - 4.1e-10 39.4 0.1 7.9e-07 28.7 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMD68972.1 - 1.3e-06 28.4 0.1 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD68972.1 - 9.4e-06 25.4 0.1 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMD68972.1 - 4.6e-05 22.2 0.1 6.9e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EMD68972.1 - 0.0002 21.3 0.4 0.00033 20.6 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EMD68972.1 - 0.00031 19.7 0.4 0.00046 19.1 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMD68972.1 - 0.00045 19.3 0.2 0.00067 18.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EMD68972.1 - 0.0018 18.6 1.0 0.01 16.2 0.7 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EMD68972.1 - 0.002 18.0 1.0 0.0054 16.6 0.7 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EMD68972.1 - 0.0051 15.7 0.1 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMD68972.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 EMD68972.1 - 0.03 14.4 0.3 0.069 13.2 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EMD68972.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Amidase PF01425.16 EMD68973.1 - 1.4e-31 109.8 0.2 2.6e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Amidase NUDIX PF00293.23 EMD68974.1 - 1e-17 64.0 0.1 1.3e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.10 EMD68975.1 - 3.9e-43 146.5 2.1 6.5e-43 145.8 1.5 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EMD68975.1 - 2.3e-27 94.6 1.1 1.1e-25 89.2 0.4 2.4 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EMD68975.1 - 0.36 10.7 3.5 0.71 9.8 1.2 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Steroid_dh PF02544.11 EMD68976.1 - 7.7e-35 119.8 0.0 1e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EMD68976.1 - 2.9e-06 27.3 0.9 7.9e-06 25.9 0.3 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMD68976.1 - 0.005 16.1 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) An_peroxidase PF03098.10 EMD68977.1 - 1.3e-102 343.9 0.0 1.5e-100 337.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EMD68977.1 - 2e-09 36.5 0.0 2.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PAD PF03068.10 EMD68980.1 - 6.5e-47 159.7 0.0 3.6e-31 107.9 0.0 2.5 2 1 0 2 2 2 2 Protein-arginine deiminase (PAD) Fungal_trans_2 PF11951.3 EMD68981.1 - 3.4e-07 29.2 0.1 5.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD68981.1 - 5.1e-07 29.5 10.7 1.1e-06 28.4 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PB1 PF00564.19 EMD68981.1 - 0.071 12.7 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 PB1 domain MmgE_PrpD PF03972.9 EMD68982.1 - 2.8e-51 174.1 10.3 1.9e-48 164.7 7.1 2.1 1 1 0 1 1 1 1 MmgE/PrpD family Tape_meas_lam_C PF09718.5 EMD68982.1 - 0.041 13.7 0.1 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) BING4CT PF08149.6 EMD68983.1 - 2.3e-37 126.3 0.0 6e-35 118.6 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EMD68983.1 - 1.4e-05 24.7 0.0 9.6e-05 22.1 0.0 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF663 PF04950.7 EMD68984.1 - 3.3e-99 331.5 0.0 6.3e-99 330.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMD68984.1 - 6e-20 70.5 0.0 1.5e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Pex26 PF07163.7 EMD68984.1 - 0.13 11.1 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein Stc1 PF12898.2 EMD68985.1 - 1.1e-22 79.8 10.3 2.2e-22 78.9 7.2 1.5 1 0 0 1 1 1 1 Stc1 domain Ribosomal_L34e PF01199.13 EMD68985.1 - 1.2 9.4 4.9 0.58 10.4 0.3 2.5 2 1 0 3 3 3 0 Ribosomal protein L34e zf-CHY PF05495.7 EMD68985.1 - 2.6 8.2 8.2 18 5.5 0.8 2.5 1 1 1 2 2 2 0 CHY zinc finger SRCR_2 PF15494.1 EMD68985.1 - 2.6 8.3 7.2 0.2 11.8 1.1 2.0 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Cytochrom_c3_2 PF14537.1 EMD68985.1 - 3.3 8.1 7.7 9.5 6.6 2.5 2.6 1 1 1 2 2 2 0 Cytochrome c3 HypA PF01155.14 EMD68985.1 - 7.1 6.3 7.9 24 4.6 3.0 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family LRR_6 PF13516.1 EMD68986.1 - 2.9e-06 26.7 1.6 0.99 9.6 0.0 6.9 9 0 0 9 9 9 1 Leucine Rich repeat LRR_4 PF12799.2 EMD68986.1 - 9.7e-06 25.0 0.0 1.1 9.0 0.0 4.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD68986.1 - 0.00012 21.7 0.0 0.71 9.6 0.0 4.0 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EMD68986.1 - 0.00019 21.0 0.0 13 6.3 0.0 5.3 4 1 0 4 4 4 1 Leucine Rich Repeat GATA PF00320.22 EMD68986.1 - 0.0066 15.7 0.3 0.016 14.5 0.2 1.6 1 0 0 1 1 1 1 GATA zinc finger LRR_7 PF13504.1 EMD68986.1 - 0.027 14.5 3.4 26 5.6 0.0 5.2 6 0 0 6 6 6 0 Leucine rich repeat YIF1 PF03878.10 EMD68987.1 - 3.2e-75 252.3 1.7 3.8e-75 252.1 1.2 1.0 1 0 0 1 1 1 1 YIF1 DUF221 PF02714.10 EMD68988.1 - 4.7e-105 351.0 15.5 8.1e-105 350.2 10.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 SRP-alpha_N PF04086.8 EMD68988.1 - 5.3e-74 249.1 0.1 5.3e-74 249.1 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EMD68988.1 - 4.5e-38 130.6 0.0 8.6e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RSN1_TM PF13967.1 EMD68988.1 - 2.8e-30 104.9 0.2 2.8e-30 104.9 0.2 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMD68988.1 - 9.9e-18 63.8 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMD68988.1 - 8.3e-10 39.0 1.7 1.6e-09 38.1 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) SRP54_N PF02881.14 EMD68988.1 - 8.9e-07 28.9 0.3 3.8e-06 26.9 0.1 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EMD68988.1 - 8.7e-06 24.7 0.0 1.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EMD68988.1 - 0.022 14.7 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EMD68988.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMD68988.1 - 0.055 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Peptidase_S10 PF00450.17 EMD68990.1 - 2.5e-80 270.7 0.3 3.5e-80 270.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HSCB_C PF07743.8 EMD68991.1 - 0.12 12.8 0.2 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4428 PF14471.1 EMD68992.1 - 0.012 15.3 1.8 5.4 6.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Trp_syntA PF00290.15 EMD68993.1 - 4.5e-91 303.9 0.0 8.8e-91 303.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain SPX PF03105.14 EMD68993.1 - 2.8e-46 158.5 8.0 4.4e-46 157.8 5.5 1.3 1 0 0 1 1 1 1 SPX domain PALP PF00291.20 EMD68993.1 - 1.7e-42 145.6 1.8 1.7e-42 145.6 1.2 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Na_sulph_symp PF00939.14 EMD68993.1 - 2.5e-32 112.4 43.7 3.5e-32 111.8 30.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMD68993.1 - 2.2e-16 59.4 46.9 3.4e-13 48.9 18.5 2.2 1 1 1 2 2 2 2 Citrate transporter PBP_sp32 PF07222.7 EMD68994.1 - 0.042 13.0 1.2 0.047 12.8 0.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNA_pol_3_Rpc31 PF11705.3 EMD68994.1 - 0.14 12.1 2.3 0.15 12.0 1.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.13 EMD68994.1 - 1.8 7.6 8.0 2.9 6.9 5.6 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Tetraspannin PF00335.15 EMD68995.1 - 0.0031 16.8 3.9 0.012 14.9 2.7 2.1 1 1 0 1 1 1 1 Tetraspanin family FAD_binding_2 PF00890.19 EMD68997.1 - 6.7e-117 390.8 7.6 6.7e-117 390.8 5.3 1.6 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMD68997.1 - 2.6e-41 140.4 3.1 4.7e-41 139.6 2.1 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMD68997.1 - 2.3e-06 27.6 0.3 0.002 18.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMD68997.1 - 0.00021 20.3 2.2 0.0051 15.7 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMD68997.1 - 0.0026 16.6 3.3 0.25 10.1 2.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EMD68997.1 - 0.0026 16.8 0.4 0.22 10.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EMD68997.1 - 0.0074 15.3 0.7 0.016 14.2 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMD68997.1 - 0.23 9.8 4.2 1.2 7.5 0.5 3.2 4 0 0 4 4 4 0 HI0933-like protein ETX_MTX2 PF03318.8 EMD68998.1 - 0.0037 16.8 11.9 0.0054 16.3 6.6 2.1 2 0 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Pro_dh PF01619.13 EMD68999.1 - 2.7e-39 135.0 0.0 3.8e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 EMD68999.1 - 0.023 13.9 0.0 0.058 12.6 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel TauD PF02668.11 EMD68999.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family P5CR_dimer PF14748.1 EMD69000.1 - 4.5e-27 94.1 2.9 7.5e-27 93.4 2.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMD69000.1 - 6.7e-07 29.6 0.1 2.5e-05 24.6 0.0 2.6 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Cyclin PF08613.6 EMD69001.1 - 5.9e-14 52.7 2.7 5.1e-13 49.6 1.8 2.2 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMD69001.1 - 0.0083 15.6 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain SnoaL PF07366.7 EMD69003.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMD69003.1 - 0.021 15.2 0.1 0.092 13.1 0.1 2.2 1 1 0 1 1 1 0 SnoaL-like domain PIP5K PF01504.13 EMD69004.1 - 1.5e-35 122.5 0.0 1.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Gly-zipper_OmpA PF13436.1 EMD69005.1 - 0.0018 17.8 2.4 0.0058 16.2 1.7 1.8 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EMD69005.1 - 0.011 15.3 16.3 0.016 14.8 11.3 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF533 PF04391.7 EMD69005.1 - 0.016 14.5 1.0 0.033 13.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gly-zipper_YMGG PF13441.1 EMD69005.1 - 3.2 7.3 14.6 5.2 6.6 10.1 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EMD69005.1 - 8.3 6.1 14.4 14 5.3 10.0 1.3 1 0 0 1 1 1 0 Glycine zipper DNA_methylase PF00145.12 EMD69009.1 - 1.5e-37 129.5 0.0 3.2e-23 82.3 0.0 2.8 1 1 1 3 3 3 3 C-5 cytosine-specific DNA methylase DUF1690 PF07956.6 EMD69010.1 - 6.4e-26 91.0 13.2 1.3e-16 60.8 5.5 2.1 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) AAA_13 PF13166.1 EMD69010.1 - 0.057 11.8 10.0 0.065 11.6 7.0 1.0 1 0 0 1 1 1 0 AAA domain Herpes_UL25 PF01499.11 EMD69010.1 - 0.07 11.4 5.4 0.083 11.1 3.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family COG2 PF06148.6 EMD69010.1 - 0.22 11.3 6.1 0.53 10.1 4.0 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 eIF3_N PF09440.5 EMD69010.1 - 1 9.5 9.1 2.4 8.3 1.7 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Cgr1 PF03879.9 EMD69010.1 - 1.1 9.4 10.1 2.9 8.0 7.0 1.8 1 1 0 1 1 1 0 Cgr1 family Tup_N PF08581.5 EMD69010.1 - 1.5 9.0 9.2 1.7 8.9 4.0 2.7 2 1 1 3 3 3 0 Tup N-terminal DUF4375 PF14300.1 EMD69010.1 - 2.9 7.9 5.1 1.8 8.5 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF1192 PF06698.6 EMD69010.1 - 3.5 7.4 7.9 3.8 7.4 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Acetyltransf_1 PF00583.19 EMD69011.1 - 2.1e-10 40.4 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CBM_1 PF00734.13 EMD69011.1 - 1.4e-09 37.4 11.6 2.5e-09 36.6 8.0 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Acetyltransf_10 PF13673.1 EMD69011.1 - 0.00075 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD69011.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMD69011.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dicty_REP PF05086.7 EMD69011.1 - 2.9 5.5 4.0 4 5.0 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_Phos_1 PF00300.17 EMD69012.1 - 4.6e-32 111.2 0.0 5.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.21 EMD69013.1 - 4.3e-14 51.8 32.1 0.0049 17.1 0.0 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-met PF12874.2 EMD69013.1 - 2.8e-09 36.8 20.7 0.0056 16.8 0.5 6.5 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMD69013.1 - 3.8e-09 36.2 31.4 0.15 12.4 0.0 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD69013.1 - 4.6e-07 29.8 29.9 0.057 13.5 0.4 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMD69013.1 - 0.0049 16.7 27.4 0.4 10.6 1.0 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMD69013.1 - 0.05 13.8 8.8 0.56 10.5 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc-ribbons_6 PF07191.7 EMD69013.1 - 1.5 8.6 16.2 3.4 7.5 0.9 4.1 3 1 1 4 4 4 0 zinc-ribbons C1_1 PF00130.17 EMD69013.1 - 1.6 8.4 14.3 8.4 6.2 2.2 4.2 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EMD69013.1 - 2.1 8.2 9.6 17 5.3 4.9 3.3 2 1 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.11 EMD69014.1 - 2.2e-27 95.7 15.2 2.2e-27 95.7 10.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD69014.1 - 5e-06 25.0 3.0 7.9e-06 24.3 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_6 PF08030.7 EMD69015.1 - 5.6e-20 71.8 0.0 3.6e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMD69015.1 - 3.8e-18 65.7 6.4 9.1e-18 64.5 4.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMD69015.1 - 3.4e-15 55.8 0.0 7.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMD69015.1 - 4.7e-05 23.9 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EMD69015.1 - 8.6 6.5 12.9 3.4 7.8 1.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Sporozoite_P67 PF05642.6 EMD69016.1 - 2.1 6.1 5.7 2.3 5.9 4.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2365 PF10157.4 EMD69017.1 - 0.0035 17.2 0.1 0.0045 16.8 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Ndc1_Nup PF09531.5 EMD69019.1 - 0.11 10.9 0.1 0.2 10.0 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MmgE_PrpD PF03972.9 EMD69020.1 - 2.6e-145 484.0 0.0 3e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family WH1 PF00568.18 EMD69021.1 - 4.6e-28 97.1 0.0 6.4e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EMD69021.1 - 8.7e-07 28.3 0.4 2e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 WH2 motif Zn_clus PF00172.13 EMD69022.1 - 2.2e-07 30.6 8.8 3.7e-07 29.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMD69022.1 - 0.0026 16.4 0.3 0.0037 15.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_15 PF01793.11 EMD69023.1 - 1.6e-117 392.1 0.2 2e-117 391.8 0.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.7 EMD69023.1 - 0.055 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF512) adh_short PF00106.20 EMD69024.1 - 2e-17 63.6 0.0 3.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69024.1 - 6.5e-13 49.0 0.0 8.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMD69024.1 - 0.0017 18.4 0.0 0.0041 17.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EMD69024.1 - 0.007 15.5 0.0 0.062 12.4 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EMD69024.1 - 0.039 13.6 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 KR domain SbcD_C PF12320.3 EMD69024.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Methyltransf_23 PF13489.1 EMD69025.1 - 6.5e-16 58.4 0.0 9.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD69025.1 - 1.1e-06 28.3 0.0 1.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD69025.1 - 1.6e-06 28.4 0.0 7.9e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD69025.1 - 4.8e-06 27.1 0.0 1.6e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD69025.1 - 1.2e-05 25.6 0.0 4.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD69025.1 - 0.079 12.0 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PBP PF01161.15 EMD69026.1 - 2.8e-05 24.0 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L37ae PF01780.14 EMD69027.1 - 2.2e-40 136.3 9.9 2.5e-40 136.2 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EMD69027.1 - 0.006 16.3 3.6 0.0093 15.7 2.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain GFA PF04828.9 EMD69027.1 - 0.011 15.6 4.3 0.23 11.4 0.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 EMD69027.1 - 0.012 15.0 3.2 0.027 13.9 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-DHHC PF01529.15 EMD69027.1 - 0.043 13.1 0.6 0.056 12.8 0.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Elf1 PF05129.8 EMD69027.1 - 0.045 13.4 2.5 0.079 12.6 1.7 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Terminase_GpA PF05876.7 EMD69027.1 - 0.059 11.7 0.5 0.067 11.5 0.4 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) CarbpepA_inh PF02977.10 EMD69027.1 - 0.066 12.7 4.8 0.12 11.9 0.2 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Zn_Tnp_IS1 PF03811.8 EMD69027.1 - 0.093 12.2 2.4 1 8.9 0.1 2.6 2 0 0 2 2 2 0 InsA N-terminal domain zf-BED PF02892.10 EMD69027.1 - 0.12 12.1 5.4 2.8 7.7 0.4 2.4 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 EMD69027.1 - 0.13 11.9 1.5 0.18 11.4 1.0 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EMD69027.1 - 0.52 10.3 2.5 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 EMD69027.1 - 1.2 9.5 4.3 13 6.3 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 EMD69027.1 - 2 8.0 5.8 1.4 8.4 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger MFS_1 PF07690.11 EMD69028.1 - 7.1e-34 117.0 34.3 8.5e-34 116.8 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.19 EMD69029.1 - 7.9e-91 302.8 58.0 1.8e-45 154.6 19.7 2.6 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EMD69029.1 - 1.6e-37 127.2 4.1 1.5e-32 111.3 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EMD69029.1 - 2.4e-37 128.2 0.0 1.5e-16 60.9 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EMD69029.1 - 1.2e-19 70.1 0.1 2.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMD69029.1 - 7.6e-07 28.7 0.0 0.00087 18.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EMD69029.1 - 1.1e-06 27.9 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EMD69029.1 - 8.3e-06 25.7 0.1 0.006 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EMD69029.1 - 6.3e-05 22.1 22.0 6.3e-05 22.1 15.2 3.1 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.1 EMD69029.1 - 0.00014 21.9 1.1 0.0033 17.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EMD69029.1 - 0.00028 20.1 0.0 0.12 11.5 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 EMD69029.1 - 0.00037 19.9 0.6 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMD69029.1 - 0.00042 19.7 0.7 0.032 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EMD69029.1 - 0.00047 20.2 0.0 1.6 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMD69029.1 - 0.0011 19.1 0.0 0.95 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD69029.1 - 0.0021 18.8 0.0 0.044 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMD69029.1 - 0.0041 17.4 0.2 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMD69029.1 - 0.017 15.0 0.3 1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMD69029.1 - 0.074 12.6 0.9 5 6.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EMD69029.1 - 0.09 12.7 0.0 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EMD69029.1 - 0.21 11.3 1.4 7.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EMD69029.1 - 0.53 9.9 2.3 3.2 7.3 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Zn_clus PF00172.13 EMD69031.1 - 2.3e-05 24.1 13.8 2.3e-05 24.1 9.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC PF00098.18 EMD69033.1 - 1.6e-05 24.5 2.0 2.7e-05 23.8 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Aldo_ket_red PF00248.16 EMD69034.1 - 9e-72 241.2 0.0 1.1e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EMD69037.1 - 4.9e-62 209.9 0.0 6.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 EMD69038.1 - 2.7e-15 55.9 0.2 3.5e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 EMD69038.1 - 0.023 13.9 0.1 1.6 7.9 0.0 2.3 1 1 0 2 2 2 0 Terpene synthase family, metal binding domain p450 PF00067.17 EMD69040.1 - 9.1e-18 64.0 0.0 2.3e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 polyprenyl_synt PF00348.12 EMD69041.1 - 1.9e-36 125.2 0.2 4.5e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EMD69041.1 - 2.3e-09 36.8 0.4 3.1e-07 29.8 0.0 2.9 2 1 1 3 3 3 2 Terpene synthase family, metal binding domain DUF1020 PF06255.8 EMD69041.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1020) ANTAR PF03861.9 EMD69041.1 - 0.061 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 ANTAR domain DUF606 PF04657.8 EMD69042.1 - 0.026 14.5 0.0 0.029 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF606 DUF755 PF05501.6 EMD69043.1 - 0.032 14.3 0.1 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Zn_clus PF00172.13 EMD69044.1 - 0.085 12.7 1.5 0.7 9.8 0.2 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 EMD69046.1 - 3.8e-10 39.2 1.4 5.2e-10 38.8 1.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Rep_fac_C PF08542.6 EMD69047.1 - 3.2e-24 84.7 0.1 1e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMD69047.1 - 1.3e-10 41.1 0.0 4e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EMD69047.1 - 4.6e-06 26.8 0.5 1.3e-05 25.4 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD69047.1 - 3.9e-05 23.8 1.5 0.00065 19.8 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD69047.1 - 5.6e-05 23.2 2.6 0.034 14.1 0.4 3.1 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EMD69047.1 - 0.0077 16.2 0.1 0.25 11.3 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 EMD69047.1 - 0.014 15.7 0.0 0.05 13.9 0.0 2.0 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.8 EMD69047.1 - 0.023 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_33 PF13671.1 EMD69047.1 - 0.024 14.4 0.3 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EMD69047.1 - 0.06 12.1 0.2 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EMD69047.1 - 0.061 12.7 0.3 1.8 7.9 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain Rad17 PF03215.10 EMD69047.1 - 0.085 11.5 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T4SS-DNA_transf PF02534.9 EMD69047.1 - 0.088 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_5 PF07728.9 EMD69047.1 - 0.12 12.1 0.5 0.35 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Aldedh PF00171.17 EMD69048.1 - 5.8e-118 394.1 0.0 7.2e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1270 PF06900.6 EMD69048.1 - 9.3 6.4 6.8 15 5.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) adh_short PF00106.20 EMD69049.1 - 9.7e-26 90.6 1.2 1.2e-25 90.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69049.1 - 2.2e-14 53.8 0.0 2.6e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69049.1 - 5.3e-09 35.9 0.7 8e-09 35.4 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMD69049.1 - 5.5e-05 22.9 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EMD69049.1 - 0.048 14.1 0.0 0.095 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EMD69049.1 - 0.076 12.3 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EMD69049.1 - 0.17 12.3 3.1 1.3 9.4 0.8 2.6 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gln-synt_C PF00120.19 EMD69050.1 - 1.8e-62 210.8 0.0 2.5e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Rpr2 PF04032.11 EMD69051.1 - 2.2e-21 75.4 0.0 3.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 EMD69052.1 - 2.6e-37 127.8 0.1 4.2e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD69052.1 - 2e-23 82.0 0.0 1.3e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMD69052.1 - 6.9e-05 22.7 0.2 0.00016 21.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMD69052.1 - 0.0019 17.2 0.0 0.0061 15.6 0.0 1.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ApbA PF02558.11 EMD69055.1 - 4.9e-24 84.4 0.0 1.6e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EMD69055.1 - 4.9e-23 81.4 0.0 7.3e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Hexokinase_1 PF00349.16 EMD69056.1 - 1.6e-66 223.5 0.1 2.3e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EMD69056.1 - 3.5e-62 209.7 0.0 4.6e-59 199.5 0.0 2.5 1 1 0 1 1 1 1 Hexokinase zf-HIT PF04438.11 EMD69058.1 - 1.2e-11 44.0 10.2 1.6e-11 43.6 7.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EMD69058.1 - 0.007 16.2 6.5 0.01 15.6 4.5 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 EMD69058.1 - 0.43 10.5 6.4 0.66 9.9 4.4 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-Mss51 PF13824.1 EMD69058.1 - 0.69 9.8 5.6 1.5 8.7 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CtaG_Cox11 PF04442.9 EMD69059.1 - 1.8e-57 193.4 0.2 2.9e-57 192.7 0.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.26 EMD69060.1 - 1.4e-21 75.9 0.9 2.4e-21 75.2 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DUF605 PF04652.11 EMD69060.1 - 4.3 6.6 17.7 6 6.1 12.3 1.3 1 0 0 1 1 1 0 Vta1 like NmrA PF05368.8 EMD69061.1 - 1.5e-30 106.2 0.7 1.9e-30 105.8 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD69061.1 - 3.3e-13 50.0 0.1 1.5e-12 47.8 0.0 1.9 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EMD69061.1 - 3.3e-07 29.6 0.5 2.7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMD69061.1 - 7.9e-05 22.2 0.1 0.00021 20.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD69061.1 - 0.0097 14.6 0.1 0.031 12.9 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMD69061.1 - 0.044 13.7 0.8 0.091 12.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EMD69061.1 - 0.058 13.3 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain PAPA-1 PF04795.7 EMD69062.1 - 8.2e-26 90.5 4.2 8.2e-26 90.5 2.9 3.3 2 1 1 3 3 3 1 PAPA-1-like conserved region ADH_N PF08240.7 EMD69063.1 - 3e-25 88.0 5.1 4.6e-25 87.5 3.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69063.1 - 8.1e-13 48.0 0.0 2.6e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD69063.1 - 0.081 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EMD69064.1 - 1.1e-30 105.7 0.0 1.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD69064.1 - 4.5e-30 103.6 0.2 1.2e-29 102.2 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 EMD69064.1 - 0.00022 21.4 0.1 0.00038 20.6 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.1 EMD69064.1 - 0.00097 20.0 0.0 0.0016 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EMD69064.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EMD69064.1 - 0.026 14.5 0.1 0.057 13.4 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMD69064.1 - 0.053 13.5 0.1 0.14 12.2 0.0 1.7 1 1 1 2 2 2 0 TrkA-N domain NUDIX PF00293.23 EMD69065.1 - 2.8e-15 56.1 0.4 3.7e-14 52.5 0.0 2.2 1 1 2 3 3 3 2 NUDIX domain p450 PF00067.17 EMD69066.1 - 1.4e-67 228.1 0.0 2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 EMD69066.1 - 0.0067 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Bacillus competence pheromone ComX Lipase_GDSL PF00657.17 EMD69067.1 - 1.9e-10 40.9 0.1 2.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMD69067.1 - 2.3e-10 40.8 0.2 2.8e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.2 EMD69069.1 - 5.8e-43 145.1 23.2 5.7e-06 26.5 0.0 11.3 6 2 5 12 12 12 10 Ankyrin repeats (3 copies) Ank PF00023.25 EMD69069.1 - 2.2e-24 83.9 31.4 0.00049 19.7 0.0 17.9 21 0 0 21 21 21 7 Ankyrin repeat Ank_4 PF13637.1 EMD69069.1 - 6.3e-14 52.0 21.7 0.0016 18.8 0.0 11.1 11 3 2 13 13 13 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69069.1 - 6.6e-13 47.5 17.0 1.3 9.4 0.0 15.5 18 1 1 19 19 19 3 Ankyrin repeat Ank_5 PF13857.1 EMD69069.1 - 1.5e-07 31.4 23.6 0.082 13.1 0.0 11.3 13 1 1 14 14 14 2 Ankyrin repeats (many copies) Zn_clus PF00172.13 EMD69070.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3455 PF11937.3 EMD69071.1 - 2.2e-35 122.1 2.2 3.7e-35 121.4 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) Exo_endo_phos PF03372.18 EMD69072.1 - 4.7e-07 29.9 1.1 6.4e-07 29.5 0.8 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EMD69072.1 - 2.8e-05 23.9 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain 4HBT PF03061.17 EMD69073.1 - 9.6e-06 25.6 0.2 5.6e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 Thioesterase superfamily NACHT PF05729.7 EMD69074.1 - 1.2e-08 34.7 0.0 3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 EMD69074.1 - 5.6e-05 23.5 0.0 0.00028 21.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 EMD69074.1 - 0.00012 22.2 0.1 0.00058 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 EMD69074.1 - 0.00015 22.0 0.0 0.00061 20.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Arch_ATPase PF01637.13 EMD69074.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EMD69074.1 - 0.0022 17.0 0.0 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ank PF00023.25 EMD69074.1 - 0.0055 16.4 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EMD69074.1 - 0.0064 16.7 0.1 0.052 13.8 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69074.1 - 0.013 15.6 0.1 1.4 9.3 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat AAA PF00004.24 EMD69074.1 - 0.014 15.6 0.1 0.15 12.2 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMD69074.1 - 0.048 14.4 0.1 0.78 10.5 0.0 2.9 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EMD69074.1 - 0.099 12.9 0.0 0.35 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EMD69075.1 - 7.9e-37 127.3 0.0 9.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FMN_dh PF01070.13 EMD69076.1 - 2.1e-120 401.8 0.0 2.5e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMD69076.1 - 3.7e-05 22.7 0.5 0.00011 21.1 0.4 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EMD69076.1 - 3.8e-05 22.8 0.1 0.034 13.2 0.1 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EMD69076.1 - 0.0012 18.0 0.8 0.0023 17.1 0.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EMD69076.1 - 0.002 17.1 0.2 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 EMD69076.1 - 0.0062 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EMD69076.1 - 0.018 14.3 0.3 1.3 8.2 0.0 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein PcrB PF01884.12 EMD69076.1 - 0.029 13.6 0.4 0.32 10.2 0.0 2.2 1 1 1 2 2 2 0 PcrB family WD40 PF00400.27 EMD69077.1 - 1.7e-30 103.7 15.8 2.1e-07 30.5 0.1 8.8 8 1 0 8 8 8 5 WD domain, G-beta repeat SGL PF08450.7 EMD69077.1 - 0.052 12.9 0.2 1.9 7.8 0.0 3.6 3 2 2 5 5 5 0 SMP-30/Gluconolaconase/LRE-like region AAA PF00004.24 EMD69079.1 - 7.1e-40 136.2 0.0 5e-38 130.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMD69079.1 - 1.4e-05 24.2 0.1 0.00018 20.6 0.0 2.8 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMD69079.1 - 0.00018 21.6 0.2 0.01 15.9 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMD69079.1 - 0.00076 19.3 3.5 0.019 14.8 0.1 3.8 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 EMD69079.1 - 0.0011 19.7 1.1 0.0037 18.0 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EMD69079.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EMD69079.1 - 0.0014 18.3 0.3 0.0091 15.7 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EMD69079.1 - 0.0016 18.2 0.0 0.0046 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMD69079.1 - 0.0026 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMD69079.1 - 0.004 17.1 0.1 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EMD69079.1 - 0.0052 15.5 0.9 0.014 14.0 0.1 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 EMD69079.1 - 0.0056 16.9 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMD69079.1 - 0.0062 15.9 0.2 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EMD69079.1 - 0.0091 15.9 3.0 0.0091 15.9 2.1 4.0 3 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EMD69079.1 - 0.067 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EMD69079.1 - 0.069 12.7 0.0 0.069 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EMD69079.1 - 0.075 12.6 0.4 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 AAA domain DUF4325 PF14213.1 EMD69080.1 - 0.045 13.3 0.2 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) vATP-synt_E PF01991.13 EMD69082.1 - 2e-62 209.9 14.2 2.3e-62 209.7 9.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.9 EMD69083.1 - 4.2e-16 58.7 4.6 5.9e-16 58.2 3.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EMD69083.1 - 0.0013 18.7 0.3 0.0013 18.7 0.2 3.2 2 1 1 3 3 3 2 EamA-like transporter family TMEM61 PF15105.1 EMD69083.1 - 0.023 14.2 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 TMEM61 protein family DUF423 PF04241.10 EMD69083.1 - 2.1 8.3 5.9 0.59 10.0 0.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF423) DUF202 PF02656.10 EMD69083.1 - 4.4 7.5 10.3 21 5.4 0.6 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 EMD69083.1 - 4.9 6.5 18.8 6 6.2 0.3 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) Neurensin PF14927.1 EMD69083.1 - 6.5 6.1 10.6 11 5.4 0.2 4.1 3 2 0 3 3 3 0 Neurensin FAD_binding_4 PF01565.18 EMD69086.1 - 9.6e-22 76.9 3.3 1.6e-21 76.2 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain Patatin PF01734.17 EMD69089.1 - 8.9e-27 94.3 0.0 2.4e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase TilS PF09179.6 EMD69089.1 - 0.03 14.3 0.0 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 TilS substrate binding domain SKG6 PF08693.5 EMD69090.1 - 0.43 9.9 3.9 1.2 8.5 2.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M20 PF01546.23 EMD69092.1 - 3.5e-24 85.3 0.1 4.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMD69092.1 - 0.00026 20.6 0.0 0.00057 19.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMD69092.1 - 0.00089 19.0 0.0 0.0023 17.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Telomere_Sde2 PF13019.1 EMD69093.1 - 2.1e-58 196.6 0.4 2.1e-58 196.6 0.3 1.5 2 0 0 2 2 2 1 Telomere stability and silencing DUF3827 PF12877.2 EMD69093.1 - 2.9 5.8 9.2 0.81 7.7 4.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) S10_plectin PF03501.10 EMD69094.1 - 1.7e-40 136.7 0.1 2e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain AdoMet_MTase PF07757.8 EMD69095.1 - 3.2e-33 114.1 0.0 1.7e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Acetyltransf_1 PF00583.19 EMD69095.1 - 3.9e-09 36.4 0.0 9.7e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD69095.1 - 7.5e-09 35.6 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.1 EMD69095.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF3906 PF13046.1 EMD69095.1 - 0.16 11.6 1.8 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) SEN1_N PF12726.2 EMD69097.1 - 1.3e-203 678.1 2.4 1.6e-203 677.7 1.7 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EMD69097.1 - 7.9e-70 235.0 2.0 7.9e-70 235.0 1.4 3.2 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EMD69097.1 - 3.5e-61 206.1 0.0 7.9e-61 204.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD69097.1 - 7.6e-11 41.6 1.0 1.6e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMD69097.1 - 1.2e-09 38.0 0.1 5.4e-06 26.1 0.1 3.0 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMD69097.1 - 9.7e-07 28.5 0.0 0.0088 15.5 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EMD69097.1 - 0.0013 17.7 0.1 0.0035 16.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EMD69097.1 - 0.0063 15.9 0.4 0.095 12.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMD69097.1 - 0.13 11.8 0.1 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMD69097.1 - 0.94 9.4 10.0 0.032 14.2 0.5 3.2 2 2 0 2 2 2 0 AAA ATPase domain AA_permease_2 PF13520.1 EMD69098.1 - 4.5e-50 170.4 41.2 5.5e-50 170.1 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD69098.1 - 3.5e-24 85.0 40.1 1.9e-23 82.5 27.7 1.8 1 1 0 1 1 1 1 Amino acid permease SRF-TF PF00319.13 EMD69099.1 - 1.4e-23 81.8 0.2 2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EMD69099.1 - 0.04 11.9 0.2 0.058 11.4 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Bd3614_N PF14442.1 EMD69099.1 - 0.14 12.1 1.3 0.24 11.3 0.9 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Tetraspannin PF00335.15 EMD69100.1 - 6.6e-09 35.3 9.2 9.4e-09 34.8 6.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2650 PF10853.3 EMD69100.1 - 1.2 8.7 3.8 5.7 6.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Syntaxin_2 PF14523.1 EMD69101.1 - 0.62 10.1 4.5 0.47 10.5 0.0 2.8 3 0 0 3 3 3 0 Syntaxin-like protein HAD PF12710.2 EMD69102.1 - 3.9e-13 50.0 0.0 1.4e-12 48.1 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMD69102.1 - 3.3e-12 45.9 1.9 3.9e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EMD69102.1 - 8.6e-12 44.8 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EMD69102.1 - 5e-10 40.1 0.2 4.7e-08 33.6 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMD69102.1 - 0.016 14.7 0.3 0.034 13.7 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CBM-like PF14683.1 EMD69104.1 - 6.9e-11 42.0 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMD69104.1 - 7.3e-10 38.8 0.0 2.9e-09 36.9 0.0 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II MFS_1 PF07690.11 EMD69105.1 - 4.6e-20 71.6 25.4 4.6e-20 71.6 17.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Lyase_1 PF00206.15 EMD69107.1 - 1.1e-92 310.5 0.0 1.8e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EMD69107.1 - 2.2e-25 88.4 0.0 6.6e-25 86.9 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal MRP-S33 PF08293.6 EMD69108.1 - 0.049 13.6 0.3 14 5.7 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal subunit S27 DOR PF14839.1 EMD69109.1 - 0.013 15.2 2.7 0.017 14.8 1.9 1.1 1 0 0 1 1 1 0 DOR family zf-CCHC PF00098.18 EMD69109.1 - 0.021 14.7 2.8 0.032 14.1 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle NDUFB10 PF10249.4 EMD69109.1 - 0.069 13.2 0.3 0.083 13.0 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HemY_N PF07219.8 EMD69109.1 - 0.31 10.6 2.5 0.35 10.4 1.7 1.2 1 0 0 1 1 1 0 HemY protein N-terminus eIF3g PF12353.3 EMD69109.1 - 0.31 10.9 4.2 0.51 10.2 2.9 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SNF2_N PF00176.18 EMD69110.1 - 4.4e-52 176.7 0.0 8.6e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD69110.1 - 2.1e-08 33.9 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD69110.1 - 0.00039 19.9 0.0 0.011 15.2 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EMD69110.1 - 0.0015 18.2 10.0 0.0015 18.2 7.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMD69110.1 - 0.0017 18.0 1.1 0.0053 16.4 0.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EMD69110.1 - 0.027 14.3 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EMD69110.1 - 0.091 12.6 9.7 0.28 11.0 6.7 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 EMD69110.1 - 0.25 10.8 9.0 4.3 6.9 6.2 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EMD69110.1 - 0.37 10.8 8.2 0.035 14.1 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) A2L_zn_ribbon PF08792.5 EMD69110.1 - 3 7.4 9.2 2.6 7.6 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EMD69110.1 - 3.2 7.7 8.2 4.2 7.4 2.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 EMD69111.1 - 1e-10 41.2 20.3 0.00037 20.6 1.0 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69111.1 - 7.7e-08 32.1 21.2 0.0026 17.9 0.3 5.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD69111.1 - 1.2e-05 25.2 13.2 0.0011 19.1 0.0 5.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-Di19 PF05605.7 EMD69111.1 - 0.00015 21.7 1.5 0.00015 21.7 1.1 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EMD69111.1 - 0.0011 19.0 8.9 0.0046 17.1 0.3 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD69111.1 - 0.002 18.1 11.8 0.025 14.7 1.0 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding NACHT PF05729.7 EMD69111.1 - 0.026 14.2 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain zf-C2H2_6 PF13912.1 EMD69111.1 - 0.49 10.3 3.2 2.8 7.9 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2470 PF10615.4 EMD69112.1 - 1.9e-16 60.0 0.5 3.1e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Transformer PF06495.6 EMD69113.1 - 0.038 13.8 5.7 0.063 13.1 3.9 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Inhibitor_I53 PF11714.3 EMD69113.1 - 0.66 10.0 6.1 0.39 10.7 2.6 1.8 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Macoilin PF09726.4 EMD69113.1 - 2.4 6.3 5.0 2.6 6.2 3.5 1.2 1 0 0 1 1 1 0 Transmembrane protein HpaP PF09483.5 EMD69113.1 - 7.6 6.4 9.7 12 5.8 6.7 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) PAPS_reduct PF01507.14 EMD69114.1 - 0.08 12.7 0.7 0.1 12.4 0.5 1.1 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family RasGEF PF00617.14 EMD69117.1 - 2.1e-44 151.5 0.0 6.9e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EMD69117.1 - 4.3e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EMD69117.1 - 2.5e-11 44.0 0.0 9.2e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EMD69117.1 - 1.5e-05 24.4 0.1 3.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Ras family AAA_33 PF13671.1 EMD69117.1 - 0.0058 16.5 0.1 0.025 14.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMD69117.1 - 0.015 16.1 0.0 0.086 13.6 0.0 2.4 1 0 0 1 1 1 0 AAA domain PRTP PF01366.13 EMD69118.1 - 0.019 13.0 0.2 0.021 12.8 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Lamp PF01299.12 EMD69119.1 - 0.055 12.6 0.0 0.055 12.6 0.0 3.1 3 1 0 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) Corona_S2 PF01601.11 EMD69119.1 - 0.21 9.6 14.0 0.3 9.1 9.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein LRR19-TM PF15176.1 EMD69119.1 - 0.43 10.2 2.7 1.1 8.9 1.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain LSR PF05624.9 EMD69119.1 - 1.1 9.0 27.3 1.7 8.4 18.9 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Prominin PF05478.6 EMD69119.1 - 7.7 3.9 17.4 11 3.4 12.0 1.1 1 0 0 1 1 1 0 Prominin TRP PF06011.7 EMD69121.1 - 6.1e-75 252.4 21.3 1e-74 251.7 14.8 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMD69121.1 - 4.7e-26 91.5 0.0 7.2e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 ML-like domain SP_C-Propep PF08999.5 EMD69121.1 - 0.012 15.0 1.7 0.082 12.3 0.0 2.8 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide 4HBT PF03061.17 EMD69122.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily GFA PF04828.9 EMD69123.1 - 1.4e-06 28.1 0.1 1.4e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EMD69123.1 - 0.043 13.3 1.8 0.071 12.6 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EMD69123.1 - 0.092 11.9 0.1 0.092 11.9 0.0 2.2 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMD69123.1 - 0.51 10.0 0.2 0.51 10.0 0.1 2.8 3 0 0 3 3 3 0 Nudix N-terminal zf-C2H2 PF00096.21 EMD69127.1 - 1.6e-10 40.6 16.0 4.5e-06 26.6 0.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69127.1 - 1e-09 37.9 9.5 3.4e-05 23.8 0.2 3.4 2 1 1 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD69127.1 - 4.4e-08 33.0 12.6 2.1e-06 27.7 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMD69127.1 - 0.00062 19.8 3.4 0.015 15.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMD69127.1 - 0.013 15.2 2.7 0.03 14.0 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 EMD69127.1 - 0.021 15.0 2.3 0.021 15.0 1.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EMD69127.1 - 0.029 14.2 4.1 1.6 8.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EMD69127.1 - 0.37 11.0 0.2 0.37 11.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 EMD69128.1 - 8.9e-72 241.3 0.0 1.6e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD69128.1 - 8.4e-32 110.2 0.0 1.7e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMD69128.1 - 0.0047 16.0 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMD69128.1 - 0.0092 15.7 0.1 0.024 14.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD69128.1 - 0.024 13.6 0.0 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EMD69128.1 - 0.065 12.8 1.6 0.067 12.7 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L24e PF01246.15 EMD69129.1 - 3.4e-31 106.9 0.5 3.4e-31 106.9 0.3 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e DREPP PF05558.7 EMD69129.1 - 0.25 11.1 12.5 0.33 10.7 8.6 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF336 PF03928.9 EMD69131.1 - 1e-36 125.6 0.4 1.2e-36 125.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Diacid_rec PF05651.8 EMD69131.1 - 0.025 14.0 4.1 0.71 9.2 0.1 2.2 1 1 0 2 2 2 0 Putative sugar diacid recognition DEC-1_N PF04625.8 EMD69131.1 - 2.3 6.8 8.7 2.7 6.5 6.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3632 PF12311.3 EMD69132.1 - 2.9e-46 157.5 2.5 3.7e-46 157.2 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AMP-binding PF00501.23 EMD69133.1 - 1.8e-73 247.3 0.0 2.6e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD69133.1 - 2.4e-14 54.0 0.7 5.8e-14 52.7 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Wbp11 PF09429.5 EMD69135.1 - 1.5e-22 79.3 17.7 1.5e-22 79.3 12.3 2.5 2 1 1 3 3 3 1 WW domain binding protein 11 HSP9_HSP12 PF04119.7 EMD69136.1 - 2.3e-22 78.8 1.3 2.3e-22 78.8 0.9 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 Glyco_hydro_76 PF03663.9 EMD69137.1 - 4.7e-46 157.8 10.3 5.9e-46 157.5 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EMD69137.1 - 0.0028 16.0 0.0 0.0036 15.6 0.0 1.4 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 EMD69137.1 - 0.032 13.5 0.6 0.17 11.1 0.2 2.2 1 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_47 PF01532.15 EMD69137.1 - 0.048 12.3 0.2 0.19 10.3 0.1 2.0 2 1 0 2 2 2 0 Glycosyl hydrolase family 47 MatE PF01554.13 EMD69138.1 - 2.6e-58 196.2 18.3 1.7e-32 112.2 2.9 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMD69138.1 - 5.5e-07 29.4 5.7 5.5e-07 29.4 4.0 4.3 3 2 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 EMD69138.1 - 0.018 14.5 4.5 0.021 14.3 0.9 2.6 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Arginase PF00491.16 EMD69139.1 - 7.9e-91 304.1 0.0 1e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMD69139.1 - 0.078 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain DUF2407_C PF13373.1 EMD69140.1 - 1.2e-36 125.6 0.0 1.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EMD69140.1 - 2.4e-27 94.9 0.0 4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMD69140.1 - 0.0029 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Dabb PF07876.7 EMD69141.1 - 2.7e-25 88.6 0.0 3.1e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.15 EMD69142.1 - 3.8e-17 62.2 0.0 4.9e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-C2HC_2 PF13913.1 EMD69142.1 - 0.54 9.9 6.7 0.49 10.1 1.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Arc PF03869.9 EMD69143.1 - 7.8e-05 22.2 2.3 0.34 10.5 0.0 3.1 3 0 0 3 3 3 2 Arc-like DNA binding domain Annexin PF00191.15 EMD69143.1 - 0.011 15.6 0.8 4.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Annexin Ribosomal_S8e PF01201.17 EMD69145.1 - 1.6e-47 160.9 2.7 1.9e-47 160.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EMD69145.1 - 0.26 11.5 3.2 0.77 10.0 2.2 2.0 1 1 0 1 1 1 0 Small acidic protein family Malate_synthase PF01274.17 EMD69146.1 - 2.3e-232 771.6 0.1 2.6e-232 771.4 0.1 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EMD69146.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Herpes_gE PF02480.11 EMD69148.1 - 0.027 12.7 0.0 0.03 12.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box-like PF12937.2 EMD69149.1 - 1e-07 31.5 0.1 2.7e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD69149.1 - 8.7e-07 28.4 0.2 4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain adh_short PF00106.20 EMD69150.1 - 8.9e-24 84.2 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69150.1 - 9.2e-10 38.4 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMD69150.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMD69150.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMD69150.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMD69150.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cytochrom_C PF00034.16 EMD69151.1 - 2.1e-08 34.8 0.1 3.5e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EMD69151.1 - 2.7e-08 33.8 2.0 1.2e-07 31.7 1.4 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EMD69151.1 - 0.0056 16.1 2.2 0.045 13.1 1.5 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EMD69151.1 - 0.015 14.9 0.1 0.021 14.4 0.1 1.4 1 1 0 1 1 1 0 Cytochrome C1 family BCDHK_Adom3 PF10436.4 EMD69152.1 - 9.7e-71 236.5 0.0 1.4e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMD69152.1 - 7.2e-18 64.3 0.0 2.9e-17 62.3 0.0 2.1 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMD69152.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SF3b10 PF07189.6 EMD69153.1 - 0.033 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) 6PF2K PF01591.13 EMD69154.1 - 1.5e-82 276.0 0.1 2.1e-82 275.5 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMD69154.1 - 2.7e-29 102.3 0.0 4.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMD69154.1 - 9.1e-08 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMD69154.1 - 0.00018 20.7 0.1 0.0003 20.0 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMD69154.1 - 0.043 14.6 0.1 0.17 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Rxt3 PF08642.5 EMD69155.1 - 1.8e-21 76.5 0.0 3.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EMD69155.1 - 5.1e-05 23.1 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 LCCL domain CLN3 PF02487.12 EMD69156.1 - 6.9e-105 351.1 15.1 1.8e-102 343.1 10.5 2.7 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EMD69156.1 - 1.9e-06 26.8 20.6 3.7e-05 22.6 13.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily EmrE PF13536.1 EMD69156.1 - 0.012 15.8 4.1 0.012 15.8 2.8 3.6 4 1 0 5 5 5 0 Multidrug resistance efflux transporter PIG-P PF08510.7 EMD69156.1 - 0.41 10.2 5.8 4.4 6.9 0.7 3.0 3 0 0 3 3 3 0 PIG-P CAF-1_p150 PF11600.3 EMD69157.1 - 0.048 13.0 25.9 0.048 13.0 18.0 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FYDLN_acid PF09538.5 EMD69157.1 - 0.45 11.1 10.5 0.6 10.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SprA-related PF12118.3 EMD69157.1 - 0.62 9.3 47.4 0.69 9.1 32.8 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 EMD69157.1 - 0.68 9.7 25.4 0.8 9.5 17.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EMD69157.1 - 0.83 8.9 22.3 0.89 8.8 15.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pneumo_phosprot PF02478.11 EMD69157.1 - 0.93 8.9 13.1 0.95 8.9 9.1 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Raftlin PF15250.1 EMD69157.1 - 1.1 7.7 19.9 1.2 7.6 13.8 1.0 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.6 EMD69157.1 - 1.5 8.2 19.0 1.5 8.2 13.2 1.0 1 0 0 1 1 1 0 PPP4R2 Spore_coat_CotO PF14153.1 EMD69157.1 - 2 7.8 31.7 2.4 7.5 21.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Dynamin_N PF00350.18 EMD69157.1 - 2.1 8.1 11.7 2.4 7.9 8.1 1.1 1 0 0 1 1 1 0 Dynamin family NARP1 PF12569.3 EMD69157.1 - 2.3 6.8 23.3 2.6 6.7 16.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_transf_15 PF01793.11 EMD69157.1 - 2.5 6.9 20.3 2.7 6.8 14.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FLO_LFY PF01698.11 EMD69157.1 - 2.7 6.7 18.8 2.9 6.6 13.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 EMD69157.1 - 2.9 6.3 20.0 3.3 6.1 13.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.7 EMD69157.1 - 3.6 7.4 25.1 4 7.3 17.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Pal1 PF08316.6 EMD69157.1 - 3.7 8.0 11.9 4.6 7.6 8.3 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein DDHD PF02862.12 EMD69157.1 - 4 7.1 21.2 4.6 6.9 14.7 1.1 1 0 0 1 1 1 0 DDHD domain Hom_end_hint PF05203.11 EMD69157.1 - 4.6 6.9 12.3 5.1 6.7 8.5 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint PIH1 PF08190.7 EMD69157.1 - 5.1 6.4 33.1 5.9 6.2 23.0 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Rtf2 PF04641.7 EMD69157.1 - 6 5.9 22.2 6.6 5.8 15.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger CobT PF06213.7 EMD69157.1 - 6.1 5.8 17.1 6.5 5.8 11.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.8 EMD69157.1 - 6.7 6.1 22.4 7.6 5.9 15.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4045 PF13254.1 EMD69157.1 - 7 5.8 24.2 7.9 5.6 16.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pox_RNA_Pol_19 PF05320.7 EMD69157.1 - 7 6.3 10.5 8.1 6.1 7.3 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4557 PF15101.1 EMD69157.1 - 7.1 6.4 35.7 8.9 6.0 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ycf1 PF05758.7 EMD69157.1 - 7.4 4.1 22.4 7.9 4.0 15.5 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EMD69157.1 - 7.5 4.4 21.3 8.2 4.3 14.8 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.5 EMD69157.1 - 7.9 5.9 23.7 9.3 5.7 16.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SpoVR PF04293.8 EMD69157.1 - 8.3 4.6 24.0 9.3 4.4 16.6 1.0 1 0 0 1 1 1 0 SpoVR like protein RNA_pol_Rpb1_2 PF00623.15 EMD69157.1 - 8.4 6.3 13.2 9.9 6.0 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Gti1_Pac2 PF09729.4 EMD69157.1 - 8.4 6.2 16.2 10 5.9 11.2 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Paf1 PF03985.8 EMD69157.1 - 8.6 4.9 27.5 9.9 4.7 19.0 1.0 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 EMD69157.1 - 8.7 5.8 18.4 10 5.6 12.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Baculo_PP31 PF05311.6 EMD69157.1 - 8.7 5.5 21.8 11 5.2 15.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gag_spuma PF03276.9 EMD69157.1 - 8.9 4.5 43.8 9.8 4.3 30.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein FAM176 PF14851.1 EMD69157.1 - 10 5.8 13.9 13 5.4 9.6 1.4 1 0 0 1 1 1 0 FAM176 family OSCP PF00213.13 EMD69158.1 - 1.9e-41 141.7 1.3 2.3e-41 141.4 0.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 EMD69158.1 - 0.043 13.5 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Asp PF00026.18 EMD69160.1 - 3.1e-12 46.3 1.3 4.4e-12 45.8 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EMD69160.1 - 3.4e-05 23.0 0.4 7.1e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EMD69160.1 - 0.0013 19.0 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EMD69160.1 - 0.0097 15.4 0.6 0.02 14.4 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.13 EMD69160.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 0 Glycophorin A Rax2 PF12768.2 EMD69160.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity IncA PF04156.9 EMD69160.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein Dehydrin PF00257.14 EMD69161.1 - 0.34 11.2 7.7 0.11 12.8 0.4 2.2 1 1 1 2 2 2 0 Dehydrin Rgp1 PF08737.5 EMD69163.1 - 1.4e-122 409.8 0.0 1.8e-121 406.1 0.0 2.3 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EMD69163.1 - 0.013 15.3 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Sigma70_ECF PF07638.6 EMD69164.1 - 0.00011 21.9 1.9 0.00012 21.8 1.3 1.1 1 0 0 1 1 1 1 ECF sigma factor SR-25 PF10500.4 EMD69164.1 - 0.00055 19.4 5.1 0.00064 19.2 3.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2956 PF11169.3 EMD69164.1 - 0.016 15.1 5.9 0.019 14.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TT_ORF2 PF02957.10 EMD69164.1 - 0.021 15.5 0.4 0.025 15.2 0.3 1.1 1 0 0 1 1 1 0 TT viral ORF2 DUF2072 PF09845.4 EMD69164.1 - 0.037 13.9 3.6 0.046 13.6 2.5 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DDHD PF02862.12 EMD69164.1 - 0.05 13.3 2.8 0.057 13.1 1.9 1.0 1 0 0 1 1 1 0 DDHD domain Med19 PF10278.4 EMD69164.1 - 0.15 11.7 9.4 0.19 11.3 6.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 UPF0172 PF03665.8 EMD69164.1 - 0.26 10.7 1.2 0.29 10.5 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF2058 PF09831.4 EMD69164.1 - 0.26 11.1 6.9 0.31 10.8 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) BLVR PF06375.6 EMD69164.1 - 0.67 9.7 8.4 0.77 9.5 5.8 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TSGP1 PF07771.6 EMD69164.1 - 3.3 7.6 7.2 4.7 7.1 5.0 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 YqfQ PF14181.1 EMD69164.1 - 4.6 7.2 8.9 5.8 6.9 6.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Herpes_DNAp_acc PF04929.7 EMD69164.1 - 4.7 6.0 7.1 5.2 5.9 4.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNase_H2-Ydr279 PF09468.5 EMD69164.1 - 8.5 5.4 7.8 10 5.2 5.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2236 PF09995.4 EMD69165.1 - 2.5e-38 131.7 0.1 4e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.6 EMD69166.1 - 2.6e-12 47.0 0.3 4.4e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EMD69166.1 - 2.5e-06 27.5 1.5 4.1e-06 26.8 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EMD69166.1 - 0.038 14.1 0.0 0.16 12.0 0.0 2.0 1 1 1 2 2 2 0 Winged helix-turn helix DUF3366 PF11846.3 EMD69167.1 - 0.08 12.8 0.2 0.093 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Pkinase PF00069.20 EMD69171.1 - 2.5e-65 220.2 0.0 4.9e-65 219.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD69171.1 - 2.6e-46 157.8 0.0 4.4e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EMD69171.1 - 3e-27 94.5 0.0 5.5e-26 90.5 0.0 2.5 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EMD69171.1 - 4.3e-16 58.4 0.3 1e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMD69171.1 - 3e-15 56.1 0.5 5.8e-15 55.2 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EMD69171.1 - 1.2e-07 30.9 0.2 0.00071 18.6 0.0 3.1 3 0 0 3 3 3 2 Kinase-like RA PF00788.18 EMD69171.1 - 6.1e-05 23.4 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IGR PF09597.5 EMD69171.1 - 0.027 14.3 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif SAM_PNT PF02198.11 EMD69171.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3322 PF11795.3 EMD69171.1 - 0.12 12.0 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Seadorna_VP7 PF07387.6 EMD69171.1 - 0.12 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 ADH_N PF08240.7 EMD69172.1 - 7e-26 90.1 2.4 7e-26 90.1 1.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69172.1 - 1e-25 89.7 2.1 1.8e-25 88.9 1.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UBA PF00627.26 EMD69174.1 - 0.00092 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain F-box PF00646.28 EMD69174.1 - 0.0037 16.8 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.3 EMD69177.1 - 9.5e-56 189.0 3.6 1.3e-55 188.5 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69177.1 - 3.4e-05 23.6 10.6 6.7e-05 22.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain L51_S25_CI-B8 PF05047.11 EMD69178.1 - 5e-15 54.9 0.0 6.4e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EMD69179.1 - 1.7e-42 144.1 0.2 2.1e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) WD40 PF00400.27 EMD69180.1 - 1.4e-13 50.1 2.6 1.5e-05 24.7 0.1 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Rav1p_C PF12234.3 EMD69180.1 - 0.6 8.1 0.1 0.91 7.6 0.1 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal UQ_con PF00179.21 EMD69181.1 - 2.2e-48 163.2 0.0 2.5e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMD69181.1 - 0.00017 21.3 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMD69181.1 - 0.016 14.8 0.1 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EMD69181.1 - 0.036 13.9 0.3 0.089 12.6 0.2 1.8 1 1 0 1 1 1 0 RWD domain Sugar_tr PF00083.19 EMD69184.1 - 2.1e-74 250.7 17.7 3e-74 250.2 12.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69184.1 - 1.7e-18 66.4 36.5 1e-15 57.3 4.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Bestrophin PF01062.16 EMD69185.1 - 3.7e-50 170.5 0.7 3.7e-48 163.9 0.5 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pmp3 PF01679.12 EMD69185.1 - 2.3 7.9 7.8 2.1 8.1 2.3 2.4 2 0 0 2 2 2 0 Proteolipid membrane potential modulator SARS_lipid_bind PF09399.5 EMD69186.1 - 0.079 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 SARS lipid binding protein ABC_tran PF00005.22 EMD69187.1 - 1.6e-49 167.7 0.0 3.4e-26 92.1 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMD69187.1 - 2.5e-19 70.3 0.4 1.2e-05 25.4 1.0 4.1 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EMD69187.1 - 6.5e-14 51.6 0.4 0.00025 20.3 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMD69187.1 - 3.9e-07 29.4 0.9 0.014 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EMD69187.1 - 4.7e-07 29.2 0.0 0.12 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 EMD69187.1 - 9.4e-07 29.3 0.0 0.0033 17.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EMD69187.1 - 1.5e-06 28.7 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMD69187.1 - 1.8e-06 27.8 0.0 0.011 15.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EMD69187.1 - 2e-06 28.6 0.0 0.13 13.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMD69187.1 - 3.8e-06 26.1 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EMD69187.1 - 6.5e-06 25.9 0.0 0.099 12.5 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit HEAT_2 PF13646.1 EMD69187.1 - 6.6e-06 26.3 1.4 0.22 11.8 0.0 3.8 1 1 3 4 4 4 2 HEAT repeats AAA_28 PF13521.1 EMD69187.1 - 1.7e-05 24.8 0.0 0.021 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMD69187.1 - 2.1e-05 24.6 0.0 0.18 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMD69187.1 - 5.6e-05 22.8 0.2 0.09 12.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EMD69187.1 - 7.3e-05 22.3 2.3 0.95 8.8 0.1 4.3 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EMD69187.1 - 0.00031 20.6 0.0 0.65 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EMD69187.1 - 0.00054 19.8 0.0 0.069 12.9 0.0 3.2 2 1 0 2 2 2 1 Dynamin family MobB PF03205.9 EMD69187.1 - 0.00071 19.2 0.1 0.34 10.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMD69187.1 - 0.00074 19.3 1.0 0.17 11.7 0.1 3.1 3 0 0 3 3 2 1 Domain of unknown function DUF87 HEAT PF02985.17 EMD69187.1 - 0.0011 18.8 0.1 20 5.6 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat RNA_helicase PF00910.17 EMD69187.1 - 0.0031 17.6 0.1 2.3 8.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 EMD69187.1 - 0.0031 16.3 0.2 0.81 8.4 0.0 2.5 2 0 0 2 2 2 1 ArgK protein Chromo PF00385.19 EMD69187.1 - 0.0031 17.1 0.1 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_25 PF13481.1 EMD69187.1 - 0.0032 16.9 0.0 1.5 8.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EMD69187.1 - 0.0033 15.9 0.0 0.87 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EMD69187.1 - 0.0042 16.5 0.1 0.3 10.5 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EMD69187.1 - 0.0085 16.3 0.2 2.1 8.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMD69187.1 - 0.0091 14.9 0.6 0.22 10.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMD69187.1 - 0.012 15.4 0.0 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMD69187.1 - 0.021 15.0 0.0 7.4 6.7 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.3 EMD69187.1 - 0.026 11.8 1.5 1.9 5.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_30 PF13604.1 EMD69187.1 - 0.031 13.8 0.4 16 5.0 0.1 3.2 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 EMD69187.1 - 0.031 13.2 0.0 2.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Septin CLASP_N PF12348.3 EMD69187.1 - 0.043 13.1 0.1 2 7.7 0.0 2.5 2 1 0 2 2 2 0 CLASP N terminal FtsK_SpoIIIE PF01580.13 EMD69187.1 - 0.046 13.2 1.4 1.9 7.9 0.1 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EMD69187.1 - 0.05 13.0 0.1 14 5.0 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EMD69187.1 - 0.059 12.8 0.0 14 5.0 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EMD69187.1 - 0.16 11.0 2.3 2.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 EMD69187.1 - 0.61 10.0 3.5 5.3 6.9 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain zf-C2H2 PF00096.21 EMD69190.1 - 2.2e-08 33.9 14.1 0.00022 21.3 0.9 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMD69190.1 - 3.7e-07 30.0 9.8 1.2e-06 28.5 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMD69190.1 - 9.8e-05 22.4 9.8 0.011 16.0 0.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EMD69190.1 - 0.031 14.4 1.5 0.031 14.4 1.1 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD69190.1 - 0.076 13.1 4.4 0.23 11.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EMD69190.1 - 0.13 12.2 1.3 2.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Pyrid_oxidase_2 PF13883.1 EMD69191.1 - 5.4e-51 172.7 0.0 6.6e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.9 EMD69192.1 - 2e-29 101.0 7.4 2.1e-29 101.0 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1687 PF07955.6 EMD69193.1 - 2.6e-15 56.5 0.8 3e-14 53.1 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EMD69193.1 - 0.0039 17.2 0.0 0.93 9.5 0.0 2.9 1 1 0 1 1 1 1 ArsC family Mus7 PF09462.5 EMD69195.1 - 1.2e-153 513.2 1.9 2e-153 512.4 1.3 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family PPTA PF01239.17 EMD69196.1 - 1.4e-38 128.6 19.2 9.2e-08 31.1 0.1 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.1 EMD69196.1 - 0.12 11.8 0.3 6.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) WD40 PF00400.27 EMD69197.1 - 3.4e-09 36.2 8.1 0.00068 19.4 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_S6e PF01092.14 EMD69198.1 - 1.1e-63 212.5 0.4 1.8e-63 211.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Calcipressin PF04847.7 EMD69199.1 - 7.4e-43 146.2 0.3 9.9e-43 145.8 0.2 1.2 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.17 EMD69199.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD69199.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_A_bac PF01000.21 EMD69200.1 - 1.2e-31 109.1 0.0 2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMD69200.1 - 8e-13 47.3 0.0 1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GrpE PF01025.14 EMD69201.1 - 2e-49 167.3 5.1 2.5e-49 167.0 3.6 1.1 1 0 0 1 1 1 1 GrpE DUF4201 PF13870.1 EMD69201.1 - 0.0054 16.1 3.9 0.0086 15.5 2.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) DUF848 PF05852.6 EMD69201.1 - 0.029 14.1 2.2 0.057 13.2 1.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PEARLI-4 PF05278.7 EMD69201.1 - 0.035 13.4 1.7 0.052 12.9 1.2 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) IncA PF04156.9 EMD69201.1 - 0.039 13.5 1.9 0.05 13.2 1.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EMD69201.1 - 0.049 13.4 10.5 0.12 12.1 7.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EMD69201.1 - 0.11 11.9 10.1 0.18 11.2 6.9 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Bap31 PF05529.7 EMD69201.1 - 0.12 11.8 5.4 0.1 12.0 3.1 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 EMD69201.1 - 0.13 12.2 8.0 0.16 11.9 4.6 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PrpF PF04303.8 EMD69202.1 - 4.9e-90 301.9 0.9 1.3e-74 251.1 0.2 2.1 2 0 0 2 2 2 2 PrpF protein Cbl_N PF02262.11 EMD69202.1 - 0.019 14.7 0.7 0.037 13.7 0.5 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DUF572 PF04502.8 EMD69202.1 - 0.094 11.9 12.9 0.032 13.4 6.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) TRAUB PF08164.7 EMD69202.1 - 0.68 10.0 8.2 1.7 8.7 5.7 1.7 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Pribosyltran_N PF13793.1 EMD69204.1 - 2.3e-44 149.8 0.1 2.5e-43 146.4 0.0 2.5 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMD69204.1 - 1.1e-43 149.1 0.5 9.3e-37 126.5 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMD69204.1 - 1.4e-11 44.1 0.5 1.3e-10 41.0 0.3 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMD69204.1 - 0.00044 19.5 0.1 0.00082 18.6 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Uds1 PF15456.1 EMD69205.1 - 2.7e-32 111.3 5.4 4.5e-32 110.6 3.7 1.4 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 EMD69205.1 - 0.084 12.4 3.3 0.15 11.6 2.3 1.4 1 0 0 1 1 1 0 IncA protein ScpA_ScpB PF02616.9 EMD69205.1 - 0.2 11.1 2.8 0.31 10.5 1.9 1.2 1 0 0 1 1 1 0 ScpA/B protein tRNA-synt_2d PF01409.15 EMD69207.1 - 6.3e-47 159.8 0.0 1.4e-26 93.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EMD69207.1 - 5.5e-23 80.9 0.0 1.7e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EMD69208.1 - 3.3e-58 193.4 2.3 9.1e-20 70.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 EMD69209.1 - 7.6e-18 64.9 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69209.1 - 3e-11 43.3 0.0 5.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD69209.1 - 4.2e-07 29.6 0.1 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMD69209.1 - 9.2e-07 28.8 0.1 1.3e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EMD69209.1 - 0.0034 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMD69209.1 - 0.0034 17.4 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMD69209.1 - 0.0034 16.3 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Angiomotin_C PF12240.3 EMD69211.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.0 1 0 0 1 1 1 0 Angiomotin C terminal HET PF06985.6 EMD69213.1 - 3.5e-21 75.8 8.1 2.7e-18 66.4 0.1 3.1 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMD69213.1 - 5.2e-21 74.7 0.0 1.5e-10 41.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD69213.1 - 1.6e-16 60.3 0.2 5.6e-09 36.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMD69213.1 - 3e-16 58.3 0.5 0.00023 20.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMD69213.1 - 6.2e-14 50.7 0.1 0.0021 18.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMD69213.1 - 5e-11 42.4 0.3 0.00039 20.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Put_DNA-bind_N PF06971.8 EMD69213.1 - 0.059 13.1 0.2 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Ank_5 PF13857.1 EMD69214.1 - 4e-21 74.5 0.1 3.6e-13 49.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD69214.1 - 3.3e-20 72.2 0.0 4.3e-16 59.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD69214.1 - 4.3e-19 67.2 0.0 2.5e-07 30.1 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMD69214.1 - 1.4e-18 66.8 0.0 3.2e-13 49.7 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69214.1 - 2.3e-17 61.3 0.0 9.5e-06 25.3 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Neil1-DNA_bind PF09292.5 EMD69214.1 - 0.059 13.1 1.3 6 6.7 0.0 3.0 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind Rad21_Rec8_N PF04825.8 EMD69215.1 - 2.1e-30 104.9 0.1 3.6e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein UCH PF00443.24 EMD69216.1 - 1.7e-57 194.5 0.0 2.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMD69216.1 - 8.3e-19 68.1 1.0 2.5e-18 66.5 0.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EMD69216.1 - 1.7e-12 46.5 0.3 5e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Cystatin PF00031.16 EMD69216.1 - 0.049 13.7 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 Cystatin domain ARPC4 PF05856.7 EMD69217.1 - 4.8e-76 253.8 4.2 5.3e-76 253.7 2.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.9 EMD69217.1 - 0.056 12.7 1.8 0.64 9.2 0.1 2.0 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc DUF1902 PF08972.6 EMD69217.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Redoxin PF08534.5 EMD69218.1 - 8.5e-38 129.1 0.0 9.5e-38 129.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMD69218.1 - 1.4e-10 40.8 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 EMD69219.1 - 1.8e-48 163.9 4.2 2.1e-48 163.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EMD69219.1 - 7.1e-06 26.3 0.2 1.1e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMD69219.1 - 0.00065 19.8 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Robl_LC7 PF03259.12 EMD69220.1 - 1.3e-10 40.6 0.0 1.1e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 EMD69221.1 - 3.1e-27 94.5 0.0 9.9e-27 92.8 0.0 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Mpv17_PMP22 PF04117.7 EMD69222.1 - 3.7e-16 58.5 0.6 3.7e-16 58.5 0.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Glyco_hydro_16 PF00722.16 EMD69223.1 - 1.9e-16 59.8 1.0 3e-16 59.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ala_racemase_N PF01168.15 EMD69224.1 - 2.5e-25 89.3 0.2 3.2e-25 88.9 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 EMD69224.1 - 2.7e-20 72.3 0.0 6.5e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Glyco_trans_4_4 PF13579.1 EMD69224.1 - 0.017 15.2 0.7 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Aminotran_3 PF00202.16 EMD69226.1 - 1.9e-95 319.6 0.0 2.3e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMD69226.1 - 3e-06 26.4 0.0 7e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SNF2_N PF00176.18 EMD69227.1 - 1.5e-33 115.9 0.0 2.2e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD69227.1 - 0.026 14.3 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain adh_short PF00106.20 EMD69229.1 - 4.2e-15 56.0 0.2 2.1e-13 50.5 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69229.1 - 4.7e-06 26.5 0.2 0.00069 19.4 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69229.1 - 3.2e-05 23.6 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 KR domain ABC_membrane_2 PF06472.10 EMD69230.1 - 6.3e-110 366.7 1.6 1e-109 366.0 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMD69230.1 - 1.6e-17 64.1 0.0 3.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMD69230.1 - 0.00017 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD69230.1 - 0.017 15.1 0.1 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EMD69230.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMD69230.1 - 0.026 14.0 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EMD69230.1 - 0.043 13.0 0.5 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.7 EMD69230.1 - 0.088 11.8 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EMD69230.1 - 0.13 11.3 0.1 0.36 9.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EMD69230.1 - 0.18 11.0 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pyr_redox_3 PF13738.1 EMD69231.1 - 1.6e-24 87.0 0.0 7.1e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD69231.1 - 1.6e-12 46.4 0.1 1e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMD69231.1 - 3.5e-08 32.7 0.0 7e-07 28.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD69231.1 - 1.6e-07 31.2 0.0 4.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMD69231.1 - 1.8e-05 24.7 0.0 0.00018 21.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 EMD69231.1 - 6.6e-05 22.6 1.8 2.1 8.3 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat LisH PF08513.6 EMD69231.1 - 0.0001 21.9 0.2 0.00022 20.8 0.1 1.5 1 0 0 1 1 1 1 LisH NAD_binding_9 PF13454.1 EMD69231.1 - 0.00038 20.2 0.2 0.023 14.4 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding eIF2A PF08662.6 EMD69231.1 - 0.0059 16.3 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Thi4 PF01946.12 EMD69231.1 - 0.034 13.2 0.1 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EMD69231.1 - 0.037 12.4 0.1 0.074 11.5 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein DUF1751 PF08551.5 EMD69232.1 - 3.6e-26 91.3 1.7 3.6e-26 91.3 1.2 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMD69232.1 - 0.84 9.6 11.4 1.7 8.6 7.9 1.6 1 0 0 1 1 1 0 Rhomboid family GATase_2 PF00310.16 EMD69233.1 - 4.4e-18 65.1 0.1 1.4e-13 50.3 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMD69233.1 - 3.9e-15 55.9 0.0 2.8e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMD69233.1 - 2.2e-13 50.0 0.0 4.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EMD69233.1 - 1.8e-11 43.8 0.0 3.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EMD69233.1 - 0.00039 19.1 0.0 0.00069 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II MSP1a PF11670.3 EMD69235.1 - 0.012 15.4 0.4 0.018 14.8 0.2 1.3 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3430 PF11912.3 EMD69235.1 - 0.023 14.5 1.8 0.026 14.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Ctf8 PF09696.5 EMD69236.1 - 7.4e-31 106.4 0.0 1.8e-30 105.1 0.0 1.6 1 1 0 1 1 1 1 Ctf8 CBM_1 PF00734.13 EMD69237.1 - 2.7e-12 46.1 10.7 2.7e-12 46.1 7.4 2.6 3 1 0 3 3 3 1 Fungal cellulose binding domain DEC-1_N PF04625.8 EMD69237.1 - 3.1 6.3 7.2 4.3 5.9 5.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region polyprenyl_synt PF00348.12 EMD69239.1 - 3.4e-16 58.8 0.2 2.4e-09 36.4 0.0 2.1 1 1 0 2 2 2 2 Polyprenyl synthetase adh_short PF00106.20 EMD69240.1 - 1.4e-05 25.1 0.4 6.3e-05 22.9 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69240.1 - 0.00056 19.6 0.1 0.0014 18.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Tweety PF04906.8 EMD69243.1 - 0.2 10.0 2.7 0.21 9.9 1.9 1.2 1 0 0 1 1 1 0 Tweety Zn_clus PF00172.13 EMD69244.1 - 3.2e-08 33.3 6.4 4.6e-08 32.8 4.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 EMD69245.1 - 4e-70 235.5 0.1 5.6e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) TYW3 PF02676.9 EMD69246.1 - 5.3e-65 218.3 0.0 6.7e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Methyltransf_23 PF13489.1 EMD69247.1 - 5e-17 62.0 0.2 1e-16 61.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD69247.1 - 3.5e-11 43.6 0.0 5.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD69247.1 - 5.2e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD69247.1 - 2e-10 41.0 0.0 4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD69247.1 - 6.8e-10 38.7 0.0 9.4e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD69247.1 - 4.3e-07 29.2 0.0 2.7e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMD69247.1 - 1.6e-06 28.4 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD69247.1 - 0.00013 21.9 0.0 0.00069 19.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain SelP_N PF04592.9 EMD69247.1 - 0.00086 18.7 7.5 0.0013 18.2 5.2 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.17 EMD69247.1 - 0.0047 15.9 0.4 0.0049 15.9 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Methyltransf_24 PF13578.1 EMD69247.1 - 0.0058 17.4 0.1 0.014 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EMD69247.1 - 0.018 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 EMD69247.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase BAF1_ABF1 PF04684.8 EMD69247.1 - 2.6 6.8 10.7 3.5 6.3 7.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_3 PF00933.16 EMD69248.1 - 6.4e-92 307.7 0.0 9.1e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD69248.1 - 2.1e-57 194.2 0.1 3.2e-56 190.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMD69248.1 - 1.5e-22 79.3 0.1 2.7e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Citrate_synt PF00285.16 EMD69249.1 - 4.2e-100 334.9 0.0 5.6e-100 334.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 EMD69250.1 - 1.2e-194 647.3 0.0 1.4e-194 647.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMD69250.1 - 8.3e-09 35.0 0.0 2.3e-07 30.2 0.0 2.3 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF726 PF05277.7 EMD69251.1 - 5.4e-121 403.6 0.2 8.3e-121 403.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pex14_N PF04695.8 EMD69251.1 - 3.7e-20 72.3 0.0 3.7e-20 72.3 0.0 4.3 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioesterase PF00975.15 EMD69251.1 - 6.6e-05 23.2 0.2 0.00031 21.0 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMD69251.1 - 0.00029 20.7 0.1 0.00094 19.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD69251.1 - 0.0012 18.4 0.0 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pro-NT_NN PF07421.6 EMD69251.1 - 0.0029 17.0 0.0 0.0078 15.7 0.0 1.6 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor Abhydrolase_5 PF12695.2 EMD69251.1 - 0.026 14.3 3.7 0.036 13.8 0.0 2.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF4293 PF14126.1 EMD69252.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) VSP PF03302.8 EMD69252.1 - 0.15 10.6 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein AMP-binding PF00501.23 EMD69253.1 - 2.8e-90 302.6 0.1 3.7e-90 302.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD69253.1 - 4.3e-22 78.8 0.2 1.7e-19 70.5 0.4 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MerE PF05052.7 EMD69253.1 - 0.056 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 MerE protein Reprolysin_5 PF13688.1 EMD69254.1 - 1.3e-59 201.3 10.2 1.3e-59 201.3 7.1 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMD69254.1 - 3.2e-47 160.7 3.7 3.2e-47 160.7 2.5 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMD69254.1 - 2.8e-45 154.5 5.6 2.8e-45 154.5 3.8 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMD69254.1 - 2.4e-19 70.0 0.9 7e-19 68.5 0.6 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EMD69254.1 - 6e-18 64.8 31.4 6e-18 64.8 21.8 4.3 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 EMD69254.1 - 0.00035 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide DUF1049 PF06305.6 EMD69254.1 - 0.1 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) NmrA PF05368.8 EMD69255.1 - 2e-11 43.6 0.0 2.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD69255.1 - 1.1e-07 32.0 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 EMD69256.1 - 0.0056 15.5 0.3 0.86 8.4 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain NACHT PF05729.7 EMD69257.1 - 1.7e-12 47.3 0.0 2.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EMD69257.1 - 0.0044 17.1 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EMD69257.1 - 0.0064 16.0 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMD69257.1 - 0.014 14.4 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.11 EMD69257.1 - 0.017 13.9 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_19 PF13245.1 EMD69257.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF159 PF02586.9 EMD69257.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 NB-ARC PF00931.17 EMD69257.1 - 0.043 12.6 0.1 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_35 PF14516.1 EMD69257.1 - 0.051 12.1 0.1 0.058 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EMD69257.1 - 0.097 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Neil1-DNA_bind PF09292.5 EMD69257.1 - 0.2 11.4 1.0 1 9.2 0.3 2.4 2 1 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind Zn_clus PF00172.13 EMD69258.1 - 2.5e-07 30.5 10.2 4.1e-07 29.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD69258.1 - 2.9e-06 26.3 1.7 4.9e-06 25.6 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.13 EMD69259.1 - 9.6e-16 57.7 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMD69259.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BTB PF00651.26 EMD69260.1 - 8.1e-26 90.1 0.2 3.2e-12 46.4 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EMD69260.1 - 1e-12 47.1 0.3 6.9e-07 28.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMD69260.1 - 1.5e-10 41.2 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD69260.1 - 1.7e-10 41.1 0.0 3.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD69260.1 - 2.2e-08 34.0 0.1 1.6e-07 31.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69260.1 - 1.6e-07 30.9 0.1 0.0012 18.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.20 EMD69261.1 - 3.3e-60 203.4 0.0 5.4e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD69261.1 - 5.2e-35 120.7 0.0 5.2e-34 117.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD69261.1 - 0.0047 15.9 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMD69261.1 - 0.06 13.0 1.3 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF572 PF04502.8 EMD69261.1 - 0.63 9.2 7.4 1.2 8.2 5.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAD_binding_8 PF08022.7 EMD69262.1 - 4.6e-19 68.2 0.0 1.2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMD69262.1 - 9.9e-19 67.7 0.0 7.5e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMD69262.1 - 1.5e-16 60.6 9.0 1.2e-15 57.6 7.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMD69262.1 - 4.9e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ctr PF04145.10 EMD69263.1 - 1.2e-33 116.1 1.5 1.5e-33 115.9 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MGC-24 PF05283.6 EMD69264.1 - 0.011 15.5 3.4 0.017 14.9 2.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) NAC PF01849.13 EMD69265.1 - 2e-21 75.2 0.1 3.2e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 NAC domain Sigma70_ner PF04546.8 EMD69265.1 - 0.074 12.6 3.6 0.18 11.4 2.2 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region IFT57 PF10498.4 EMD69265.1 - 0.25 10.0 3.5 0.11 11.1 0.9 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Pyr_redox_2 PF07992.9 EMD69266.1 - 5.9e-12 45.8 0.0 7.9e-06 25.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD69266.1 - 9.4e-07 29.0 0.1 0.049 13.6 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD69266.1 - 0.00078 19.7 0.0 0.19 12.1 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD69266.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RNase_PH PF01138.16 EMD69267.1 - 9.7e-19 67.9 0.0 1.5e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1996 PF09362.5 EMD69268.1 - 1.9e-56 191.3 0.6 3e-56 190.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AMP-binding PF00501.23 EMD69269.1 - 1.7e-68 230.9 0.0 2.4e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD69269.1 - 3.5e-09 37.4 0.0 1.9e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Dynamin_N PF00350.18 EMD69270.1 - 1e-13 51.4 3.3 5.3e-13 49.1 0.5 2.6 2 1 1 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EMD69270.1 - 9.5e-10 37.7 0.8 1.6e-09 36.9 0.2 1.8 2 1 0 2 2 2 1 Dynamin central region CagA PF03507.8 EMD69270.1 - 0.037 13.8 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 CagA exotoxin DUF4548 PF15081.1 EMD69270.1 - 0.11 12.0 0.2 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) cobW PF02492.14 EMD69271.1 - 9.1e-35 119.7 0.0 1.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EMD69271.1 - 8.8e-08 31.2 0.2 0.00019 20.2 0.1 2.1 2 0 0 2 2 2 2 ArgK protein ResIII PF04851.10 EMD69271.1 - 0.0035 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EMD69271.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EMD69271.1 - 0.017 15.9 0.2 0.032 15.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMD69271.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMD69271.1 - 0.078 12.3 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 EMD69271.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EMD69271.1 - 0.1 11.3 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus KAP_NTPase PF07693.9 EMD69271.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EMD69271.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EMD69271.1 - 0.14 11.9 0.1 0.57 9.8 0.0 2.1 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EMD69271.1 - 0.15 12.3 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ProSAAS PF07259.7 EMD69272.1 - 0.058 12.9 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 ProSAAS precursor Fer4_6 PF12837.2 EMD69272.1 - 3.2 7.7 7.0 0.85 9.6 0.9 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2_4 PF13894.1 EMD69272.1 - 3.3 8.2 6.5 3.3 8.2 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-AD PF07776.10 EMD69272.1 - 6.1 6.9 7.6 1.2 9.1 0.3 2.9 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.21 EMD69272.1 - 9.5 6.7 7.3 1.7 9.1 0.7 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF566 PF04484.7 EMD69273.1 - 2 7.8 7.1 2.8 7.3 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) AMP-binding PF00501.23 EMD69274.1 - 2.3e-72 243.6 0.0 3.2e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMD69274.1 - 4.8e-67 225.5 0.0 1.3e-66 224.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EMD69274.1 - 2.3e-11 43.7 0.0 5.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMD69274.1 - 3e-09 37.6 0.0 1.1e-08 35.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EMD69274.1 - 3.1e-09 36.6 0.0 7.6e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMD69274.1 - 0.00011 21.0 0.0 0.00026 19.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMD69274.1 - 0.0021 18.1 0.0 0.024 14.6 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding IBR PF01485.16 EMD69276.1 - 7.9e-08 32.0 21.7 6.2e-06 25.9 5.0 2.7 3 0 0 3 3 3 2 IBR domain zf-LYAR PF08790.6 EMD69276.1 - 7.4 6.3 11.3 4.8 6.9 0.0 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Ank_2 PF12796.2 EMD69277.1 - 9.5e-10 38.6 0.1 1.9e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD69277.1 - 0.0071 16.8 0.0 0.22 12.0 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Glyco_hydro_76 PF03663.9 EMD69278.1 - 2e-148 494.7 20.7 2.4e-148 494.4 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.16 EMD69279.1 - 4.4e-33 112.7 0.6 5.1e-33 112.5 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF619 PF04768.8 EMD69280.1 - 1.4e-37 128.6 0.2 2.6e-37 127.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EMD69280.1 - 1.4e-31 109.2 0.0 3.6e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EMD69280.1 - 6.2e-25 88.1 0.0 1.2e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 EMD69280.1 - 0.00043 20.8 0.0 0.0027 18.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EMD69280.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glu-tRNAGln PF02686.10 EMD69282.1 - 9.6e-05 22.1 0.3 0.00039 20.1 0.1 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Caps_synth_GfcC PF06251.6 EMD69282.1 - 0.095 11.8 0.5 0.18 10.9 0.3 1.3 1 1 0 1 1 1 0 Capsule biosynthesis GfcC SNAP PF14938.1 EMD69283.1 - 6.5e-112 373.2 16.5 7.3e-112 373.1 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EMD69283.1 - 0.0002 21.2 14.8 0.035 14.0 0.6 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69283.1 - 0.0066 16.0 18.7 0.18 11.4 1.9 3.9 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EMD69283.1 - 0.024 15.3 20.8 0.041 14.5 2.6 3.8 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69283.1 - 0.085 12.8 19.9 2 8.5 0.1 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69283.1 - 1.1 8.9 20.2 4 7.2 0.4 6.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD69283.1 - 1.9 9.1 17.9 5.2 7.7 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMD69283.1 - 2.9 7.7 9.3 4.3 7.2 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fasciclin PF02469.17 EMD69284.1 - 6.5e-44 149.0 0.0 3.3e-23 82.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Pyridoxal_deC PF00282.14 EMD69285.1 - 1.6e-60 204.5 0.0 2.1e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMD69285.1 - 3.2e-05 22.8 0.0 5.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_7 PF03441.9 EMD69286.1 - 6e-57 192.9 0.0 8.4e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMD69286.1 - 1.3e-10 41.3 0.0 3.7e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 DNA photolyase PGA2 PF07543.7 EMD69289.1 - 1.3e-16 60.6 0.0 1.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 GBP PF02263.14 EMD69289.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain CENP-S PF15630.1 EMD69290.1 - 1.8e-33 114.5 0.0 2.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EMD69290.1 - 5.8e-06 25.8 0.7 9.2e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EMD69290.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMD69290.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EMD69290.1 - 0.034 14.2 0.1 0.08 13.0 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EMD69290.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sigma70_r4_2 PF08281.7 EMD69291.1 - 0.00016 21.0 0.2 0.00038 19.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 EMD69291.1 - 0.00028 20.4 0.1 0.00091 18.7 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EMD69291.1 - 0.00096 19.2 0.0 0.0079 16.3 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix GerE PF00196.14 EMD69291.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EMD69291.1 - 0.017 14.6 0.1 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.1 EMD69291.1 - 0.026 14.5 1.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2316 PF10078.4 EMD69291.1 - 0.027 14.4 0.0 0.034 14.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Homeobox PF00046.24 EMD69291.1 - 0.039 13.5 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Homeobox domain HTH_11 PF08279.7 EMD69291.1 - 0.043 13.4 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_Tnp_IS630 PF01710.11 EMD69291.1 - 0.046 13.3 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_Mga PF08280.6 EMD69291.1 - 0.049 13.3 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_10 PF04967.7 EMD69291.1 - 0.05 13.1 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.1 EMD69291.1 - 0.067 12.5 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Terminase_5 PF06056.7 EMD69291.1 - 0.078 12.5 0.2 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Crp_2 PF13545.1 EMD69291.1 - 0.11 12.2 0.0 2.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Erythro-docking PF09277.6 EMD69292.1 - 0.0066 16.1 0.1 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Erythronolide synthase, docking NIF PF03031.13 EMD69292.1 - 0.057 13.0 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase FA_FANCE PF11510.3 EMD69292.1 - 0.14 11.2 0.3 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE TPR_12 PF13424.1 EMD69293.1 - 5.3e-192 622.2 90.3 8.3e-19 67.3 0.3 10.4 2 2 12 15 15 15 15 Tetratricopeptide repeat TPR_10 PF13374.1 EMD69293.1 - 1.2e-162 523.9 80.1 8.4e-13 47.7 0.1 17.7 18 0 0 18 18 17 16 Tetratricopeptide repeat TPR_4 PF07721.9 EMD69293.1 - 3.1e-31 104.5 12.7 0.85 10.2 0.0 14.6 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMD69293.1 - 7.4e-30 100.6 12.7 0.18 12.0 0.0 14.1 16 0 0 16 16 13 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69293.1 - 1.6e-28 96.1 35.3 0.02 14.6 0.0 15.4 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69293.1 - 3.1e-26 89.8 44.5 0.16 11.6 0.0 15.5 16 0 0 16 16 16 9 Tetratricopeptide repeat Apc3 PF12895.2 EMD69293.1 - 8.3e-22 77.1 28.6 0.0054 16.8 0.8 8.9 1 1 8 10 10 10 10 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMD69293.1 - 1.3e-21 76.6 26.7 0.11 13.2 0.1 10.7 9 2 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69293.1 - 2.7e-21 74.9 34.3 0.00028 20.4 0.1 10.8 3 2 9 14 14 14 9 TPR repeat Rab5-bind PF09311.6 EMD69293.1 - 1.3e-17 64.2 27.4 0.084 12.7 0.1 9.7 2 2 9 11 11 11 10 Rabaptin-like protein TPR_2 PF07719.12 EMD69293.1 - 8e-15 53.4 48.7 0.33 10.9 0.2 16.0 16 0 0 16 16 16 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMD69293.1 - 1.2e-14 53.4 40.6 11 6.9 0.0 16.5 16 1 1 17 17 17 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMD69293.1 - 1.9e-13 50.5 20.1 0.023 15.0 0.1 11.3 3 2 12 15 15 15 7 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69293.1 - 1e-10 40.5 19.9 9.3 6.2 0.0 11.5 12 0 0 12 12 12 0 Tetratricopeptide repeat NACHT PF05729.7 EMD69293.1 - 2.2e-06 27.4 0.1 7.1e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF627 PF04781.7 EMD69293.1 - 7.2e-06 25.5 12.0 10 5.7 0.0 8.2 2 2 5 7 7 7 0 Protein of unknown function (DUF627) NB-ARC PF00931.17 EMD69293.1 - 2.2e-05 23.4 0.0 5.4e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Extensin-like_C PF06904.7 EMD69293.1 - 0.026 14.3 8.7 1.2 8.9 0.8 2.5 2 0 0 2 2 2 0 Extensin-like protein C-terminus Glyco_hydro_61 PF03443.9 EMD69294.1 - 9.9e-46 156.2 0.0 9.9e-46 156.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMD69294.1 - 8.9e-12 44.4 4.5 8.9e-12 44.4 3.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain RabGAP-TBC PF00566.13 EMD69295.1 - 1.8e-48 164.8 1.6 4.2e-48 163.6 0.0 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF4472 PF14739.1 EMD69295.1 - 0.0096 16.3 17.9 0.048 14.1 7.6 2.7 1 1 0 2 2 2 2 Domain of unknown function (DUF4472) SPAM PF02090.10 EMD69295.1 - 0.085 12.8 7.2 0.076 13.0 3.6 1.9 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF972 PF06156.8 EMD69295.1 - 1.5 9.2 21.4 5 7.5 6.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PspB PF06667.7 EMD69295.1 - 1.8 8.5 6.5 3 7.8 0.6 2.7 1 1 1 2 2 2 0 Phage shock protein B TMEM171 PF15471.1 EMD69295.1 - 2.6 6.7 5.2 4.8 5.8 3.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DivIC PF04977.10 EMD69295.1 - 4.9 6.7 18.2 0.34 10.4 3.7 3.6 1 1 2 3 3 3 0 Septum formation initiator KH_1 PF00013.24 EMD69296.1 - 9.5e-42 140.4 14.0 4.3e-15 55.0 1.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMD69296.1 - 3.6e-28 96.6 18.4 1.2e-10 40.8 1.0 3.8 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EMD69296.1 - 6.7e-14 51.2 5.1 0.00012 21.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMD69296.1 - 3e-10 39.5 1.6 0.0022 17.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMD69296.1 - 8.1e-05 22.3 4.1 0.02 14.6 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain Ald_Xan_dh_C2 PF02738.13 EMD69297.1 - 1.1e-196 654.4 1.2 1.6e-196 653.9 0.8 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMD69297.1 - 8.9e-48 161.9 0.0 1.8e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EMD69297.1 - 4.5e-35 120.0 0.1 1.1e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EMD69297.1 - 5.6e-34 116.1 0.3 2.4e-33 114.1 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EMD69297.1 - 3.1e-28 97.4 0.0 6.8e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EMD69297.1 - 6e-08 32.3 0.1 6e-08 32.3 0.1 2.7 3 1 1 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EMD69297.1 - 0.092 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-70 region 3 UvdE PF03851.9 EMD69298.1 - 3.4e-113 377.2 0.0 4.4e-113 376.8 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Fungal_trans_2 PF11951.3 EMD69299.1 - 3.8e-51 173.8 0.1 5.7e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69299.1 - 1.2e-07 31.5 7.6 2.3e-07 30.6 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.14 EMD69300.1 - 5e-39 134.3 0.1 2.1e-29 102.8 0.1 2.1 2 0 0 2 2 2 2 HMGL-like SUR7 PF06687.7 EMD69302.1 - 0.0012 18.4 2.3 0.63 9.5 1.9 2.2 2 0 0 2 2 2 2 SUR7/PalI family MARVEL PF01284.18 EMD69302.1 - 0.0048 16.7 13.4 0.0071 16.1 9.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srz PF10325.4 EMD69302.1 - 0.07 12.2 1.9 0.45 9.6 0.6 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz Nfu_N PF08712.6 EMD69303.1 - 6.6e-28 96.1 0.0 2.8e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EMD69303.1 - 8.1e-22 76.7 0.1 1.3e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain DUF848 PF05852.6 EMD69304.1 - 0.0031 17.3 0.2 0.0059 16.4 0.2 1.4 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Perilipin PF03036.11 EMD69304.1 - 0.02 13.7 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Perilipin family Med28 PF11594.3 EMD69304.1 - 0.021 15.0 2.3 0.54 10.5 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 NPV_P10 PF05531.7 EMD69304.1 - 0.038 14.2 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3209 PF11483.3 EMD69304.1 - 0.09 13.1 0.2 1 9.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) Chorismate_bind PF00425.13 EMD69305.1 - 2.1e-88 295.9 0.0 1e-87 293.7 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EMD69305.1 - 1.8e-30 105.8 0.1 1.4e-26 93.2 0.0 3.4 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region CFEM PF05730.6 EMD69306.1 - 6.2e-11 41.9 9.7 1.9e-10 40.4 6.7 1.8 1 0 0 1 1 1 1 CFEM domain Mitofilin PF09731.4 EMD69306.1 - 0.74 8.4 10.1 0.91 8.1 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GFO_IDH_MocA PF01408.17 EMD69307.1 - 1.6e-28 99.6 0.2 2.6e-28 98.9 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMD69307.1 - 0.00031 20.5 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.1 EMD69307.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_N PF08240.7 EMD69309.1 - 6.5e-27 93.4 1.8 6.7e-27 93.4 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69309.1 - 2.8e-16 59.2 0.9 7.7e-16 57.8 0.6 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EMD69309.1 - 0.0027 17.5 0.5 0.0057 16.4 0.3 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EMD69309.1 - 0.021 14.9 0.9 0.12 12.4 0.2 2.3 1 1 2 3 3 3 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EMD69309.1 - 0.044 14.3 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EMD69310.1 - 6.3e-31 107.5 2.3 6.3e-31 107.5 1.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69310.1 - 3.3e-23 82.6 0.1 4.1e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69310.1 - 3.7e-14 52.7 1.1 6.7e-14 51.9 0.8 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD69310.1 - 0.00026 20.7 0.2 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMD69310.1 - 0.0012 18.3 0.1 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.6 EMD69310.1 - 0.0026 17.2 0.0 0.041 13.3 0.0 2.4 2 1 1 3 3 3 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.14 EMD69310.1 - 0.012 14.6 0.1 0.071 12.1 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMD69310.1 - 0.017 15.1 1.9 0.17 11.8 0.5 2.6 2 1 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 EMD69310.1 - 0.018 14.2 0.2 0.033 13.4 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 EMD69310.1 - 0.091 13.1 0.9 1.3 9.5 0.1 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CW_binding_2 PF04122.7 EMD69310.1 - 0.1 12.8 0.2 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Aldo_ket_red PF00248.16 EMD69311.1 - 7.3e-48 162.8 0.0 9.4e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF706 PF05153.10 EMD69312.1 - 2e-126 420.4 5.8 2.8e-126 420.0 4.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) tRNA-synt_1 PF00133.17 EMD69313.1 - 1.4e-32 112.4 0.0 3.4e-24 84.8 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMD69313.1 - 2.7e-15 55.9 0.0 4.2e-09 35.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMD69313.1 - 9e-13 48.2 0.9 3.1e-12 46.5 0.7 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMD69313.1 - 1.5e-08 34.1 0.0 3.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ribonuclease PF00545.15 EMD69314.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 ribonuclease ATP-synt_ab PF00006.20 EMD69315.1 - 8.9e-61 205.1 0.0 1.1e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMD69315.1 - 2.3e-16 60.2 0.0 4.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMD69315.1 - 1.3e-12 47.7 0.7 2.6e-12 46.7 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMD69315.1 - 0.00057 19.7 0.3 0.0012 18.6 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain LIM_bind PF01803.11 EMD69316.1 - 3e-56 190.2 0.5 3e-56 190.2 0.3 4.7 3 1 0 3 3 3 1 LIM-domain binding protein LMBR1 PF04791.11 EMD69316.1 - 4.6 5.6 14.0 6.8 5.1 9.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein LAM_C PF12544.3 EMD69317.1 - 1.9e-05 24.7 0.0 5.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EMD69317.1 - 0.004 17.3 0.1 0.011 15.8 0.0 1.9 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 EMD69317.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.1 EMD69317.1 - 0.022 14.8 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Couple_hipA PF13657.1 EMD69317.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 HipA N-terminal domain GET2 PF08690.5 EMD69319.1 - 2.1e-06 27.1 8.8 0.0016 17.7 0.0 3.0 1 1 1 2 2 2 2 GET complex subunit GET2 TRAM_LAG1_CLN8 PF03798.11 EMD69319.1 - 0.042 13.3 0.1 0.064 12.7 0.1 1.3 1 0 0 1 1 1 0 TLC domain PTH2 PF01981.11 EMD69320.1 - 2.8e-47 159.2 0.1 3.6e-47 158.8 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribosomal_L28 PF00830.14 EMD69321.1 - 1.7e-18 66.1 1.2 3.8e-18 65.0 0.8 1.6 1 0 0 1 1 1 1 Ribosomal L28 family F-box-like_2 PF13013.1 EMD69322.1 - 0.00012 21.7 0.0 0.00037 20.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain TPR_2 PF07719.12 EMD69322.1 - 0.044 13.7 0.0 0.2 11.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69322.1 - 0.063 12.9 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 TPR repeat PMI_typeI PF01238.16 EMD69323.1 - 7e-77 258.9 0.0 4.7e-76 256.1 0.0 1.8 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EMD69323.1 - 4.6e-07 29.2 0.0 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EMD69323.1 - 0.00067 19.3 0.0 0.0086 15.7 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Glyco_transf_34 PF05637.7 EMD69324.1 - 1e-64 218.3 0.0 1.3e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MMR_HSR1 PF01926.18 EMD69325.1 - 0.00012 21.9 0.0 0.00099 19.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Aminotran_1_2 PF00155.16 EMD69326.1 - 2e-88 296.7 0.0 2.3e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.18 EMD69327.1 - 3.1e-11 43.1 0.5 4.4e-11 42.6 0.0 1.6 2 1 0 2 2 2 1 Hpt domain Cep57_MT_bd PF06657.8 EMD69327.1 - 0.065 13.1 0.6 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF356 PF04009.7 EMD69327.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DUF3887 PF13026.1 EMD69327.1 - 0.16 12.2 8.5 0.42 10.9 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) YojJ PF10372.4 EMD69327.1 - 0.17 11.7 2.4 9.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DHC_N1 PF08385.7 EMD69327.1 - 0.25 9.7 4.6 0.3 9.4 3.2 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Seryl_tRNA_N PF02403.17 EMD69327.1 - 4.4 7.3 7.4 2.8 8.0 1.6 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Isy1 PF06246.7 EMD69327.1 - 5.6 6.2 9.6 8.5 5.6 5.5 1.8 1 1 0 1 1 1 0 Isy1-like splicing family AKAP7_NLS PF10469.4 EMD69328.1 - 1.1e-23 84.0 0.0 1.9e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EMD69328.1 - 6.6e-05 22.6 0.1 0.00015 21.4 0.1 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Sensor_TM1 PF13755.1 EMD69329.1 - 0.011 15.2 1.7 0.42 10.1 0.0 3.3 3 0 0 3 3 3 0 Sensor N-terminal transmembrane domain Cutinase PF01083.17 EMD69331.1 - 2.9e-47 160.7 10.4 3.4e-47 160.4 7.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMD69331.1 - 4.7e-05 22.9 0.1 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EMD69331.1 - 0.00047 19.7 0.1 0.0023 17.5 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold VirJ PF06057.6 EMD69331.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EMD69331.1 - 0.015 15.1 0.0 0.6 9.9 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD69331.1 - 0.027 14.2 0.9 0.084 12.6 0.7 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EMD69331.1 - 0.75 9.0 5.2 2.2 7.5 3.6 1.7 1 1 0 1 1 1 0 Lipase (class 2) DAO PF01266.19 EMD69332.1 - 1.8e-47 161.9 0.0 2.9e-47 161.3 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMD69332.1 - 1.1e-07 31.6 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMD69332.1 - 1e-06 28.9 2.2 0.00076 19.5 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMD69332.1 - 4.4e-05 23.4 0.1 0.15 11.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD69332.1 - 0.00037 19.2 0.1 0.0043 15.7 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EMD69332.1 - 0.00057 19.8 0.4 0.0031 17.4 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD69332.1 - 0.00058 18.8 0.3 0.38 9.6 0.0 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 EMD69332.1 - 0.00094 18.1 0.5 0.0021 16.9 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A ThiF PF00899.16 EMD69332.1 - 0.039 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EMD69332.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_3_C PF01915.17 EMD69333.1 - 1.1e-59 201.6 0.4 1.8e-59 201.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EMD69333.1 - 1.2e-59 201.8 0.0 1.6e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EMD69333.1 - 3.9e-21 74.7 1.9 3.9e-21 74.7 1.3 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 EMD69333.1 - 0.00044 20.2 4.2 0.0017 18.3 2.2 2.5 1 1 1 2 2 2 1 Domain of unknown function DUF11 Sugar-bind PF04198.8 EMD69333.1 - 0.018 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Levi_coat PF01819.12 EMD69333.1 - 0.049 13.2 1.0 0.13 11.8 0.7 1.7 1 0 0 1 1 1 0 Levivirus coat protein His_Phos_1 PF00300.17 EMD69335.1 - 2.8e-25 89.2 0.0 3.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EPL1 PF10513.4 EMD69336.1 - 0.71 10.1 6.7 1.5 9.0 4.6 1.5 1 1 0 1 1 1 0 Enhancer of polycomb-like MFS_1 PF07690.11 EMD69337.1 - 8.7e-24 83.8 16.8 1.1e-23 83.5 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD69337.1 - 3.9e-05 23.3 1.0 0.00016 21.3 0.3 2.4 2 0 0 2 2 2 1 MFS_1 like family CBFB_NFYA PF02045.10 EMD69337.1 - 0.082 13.4 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TauD PF02668.11 EMD69338.1 - 6.9e-52 176.6 0.5 8.3e-52 176.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EMD69338.1 - 0.026 15.0 0.2 0.49 10.9 0.0 2.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF913 PF06025.7 EMD69339.1 - 1e-117 393.1 0.0 1e-117 393.1 0.0 5.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EMD69339.1 - 1.3e-94 316.9 0.1 2.3e-94 316.1 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EMD69339.1 - 2.2e-85 286.8 0.0 2.8e-84 283.2 0.0 3.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EMD69339.1 - 5.6e-26 90.5 21.1 5.6e-26 90.5 14.6 5.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) GCN5L1 PF06320.8 EMD69340.1 - 2.3e-12 46.8 2.4 3.1e-12 46.4 1.6 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.3 EMD69340.1 - 0.018 14.2 1.3 0.018 14.2 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) HAUS6_N PF14661.1 EMD69340.1 - 0.28 10.4 4.1 0.32 10.2 2.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Syntaxin-6_N PF09177.6 EMD69340.1 - 1 9.7 4.3 3.2 8.2 0.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Alb1 PF09135.6 EMD69340.1 - 9.9 6.8 9.5 50 4.5 6.6 1.9 1 1 0 1 1 1 0 Alb1 Cutinase PF01083.17 EMD69341.1 - 3.1e-45 154.0 0.0 4.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EMD69341.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EMD69341.1 - 0.12 11.7 0.1 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 PE-PPE domain Acetyltransf_1 PF00583.19 EMD69342.1 - 2.4e-07 30.6 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD69342.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD69342.1 - 2e-05 24.7 0.1 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain YbaJ PF10757.4 EMD69344.1 - 0.14 12.2 2.0 2.8 8.1 1.4 2.8 1 1 0 1 1 1 0 Biofilm formation regulator YbaJ Phasin PF05597.6 EMD69344.1 - 0.2 11.4 0.3 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Vps39_1 PF10366.4 EMD69346.1 - 1.8e-33 114.8 0.0 1.7e-32 111.6 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EMD69346.1 - 1.7e-31 108.5 0.0 1.1e-30 106.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EMD69346.1 - 9.4e-22 77.7 0.0 3.2e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EMD69346.1 - 1.5e-06 27.8 4.4 1.5e-06 27.8 3.1 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_12 PF13424.1 EMD69346.1 - 0.00015 21.6 6.8 0.78 9.7 0.6 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD69346.1 - 0.00017 21.8 12.9 0.089 13.1 1.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EMD69346.1 - 0.00049 20.1 8.0 0.0014 18.7 0.1 3.3 3 1 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMD69346.1 - 0.0026 17.2 9.6 3 7.5 1.6 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69346.1 - 0.004 17.7 12.3 2.2 9.0 0.6 5.6 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69346.1 - 0.0098 15.7 7.4 6.9 6.8 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMD69346.1 - 0.034 14.0 3.2 14 5.8 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69346.1 - 0.06 13.0 9.0 7 6.3 0.2 4.6 3 2 0 3 3 3 0 TPR repeat PPR PF01535.15 EMD69346.1 - 0.16 12.0 0.2 8.3 6.6 0.0 3.1 2 0 0 2 2 2 0 PPR repeat APC8 PF04049.8 EMD69346.1 - 0.17 11.5 1.2 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 EMD69346.1 - 0.4 10.5 10.3 2.1 8.3 0.5 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMD69346.1 - 3 7.7 5.3 16 5.4 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HbrB PF08539.6 EMD69347.1 - 6.5e-53 178.7 0.0 9.7e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Cupin_3 PF05899.7 EMD69348.1 - 2.7e-05 23.4 0.1 5.3e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 EMD69348.1 - 0.00077 19.0 0.0 0.00089 18.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Retinal PF15449.1 EMD69349.1 - 0.12 10.0 13.1 0.12 10.0 9.1 1.1 1 0 0 1 1 1 0 Retinal protein COesterase PF00135.23 EMD69350.1 - 1.6e-78 264.7 0.1 2.8e-77 260.6 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD69350.1 - 3.6e-07 29.9 0.3 2.2e-06 27.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD69350.1 - 9.1e-06 25.0 0.4 1.7e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD69350.1 - 0.0037 17.0 1.3 0.012 15.3 0.3 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1674 PF07896.7 EMD69351.1 - 1.7e-16 60.1 3.0 3.7e-16 59.0 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Macoilin PF09726.4 EMD69351.1 - 0.12 10.6 0.6 0.15 10.3 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein ORC6 PF05460.8 EMD69351.1 - 0.56 9.2 5.4 0.63 9.0 3.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MAGE_N PF12440.3 EMD69351.1 - 4.1 7.7 13.8 1.7 8.9 7.6 1.8 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal TIP49 PF06068.8 EMD69352.1 - 9.3e-181 600.8 0.0 1.1e-180 600.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMD69352.1 - 1.3e-10 41.5 0.1 2.9e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMD69352.1 - 3.3e-09 36.1 0.2 1.3e-06 27.6 0.0 2.5 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMD69352.1 - 5.8e-08 32.9 0.1 1.7e-05 24.8 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMD69352.1 - 2.9e-05 24.2 0.1 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EMD69352.1 - 3.4e-05 23.8 0.5 0.00092 19.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMD69352.1 - 4.9e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMD69352.1 - 0.00026 20.7 0.1 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMD69352.1 - 0.00054 19.1 0.2 0.0012 17.9 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EMD69352.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EMD69352.1 - 0.0015 18.0 0.1 0.46 9.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMD69352.1 - 0.009 15.4 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMD69352.1 - 0.016 14.4 0.2 0.51 9.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EMD69352.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EMD69352.1 - 0.029 14.6 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EMD69352.1 - 0.038 13.1 0.2 0.077 12.0 0.0 1.7 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 EMD69352.1 - 0.038 13.4 0.3 5 6.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DnaB_C PF03796.10 EMD69352.1 - 0.038 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EMD69352.1 - 0.068 13.9 0.1 0.16 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMD69352.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Bromodomain PF00439.20 EMD69353.1 - 4.8e-41 138.5 2.7 4.2e-22 77.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EMD69354.1 - 4.9e-24 84.3 0.1 8.1e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.5 EMD69354.1 - 0.087 11.8 26.1 0.013 14.5 10.4 2.2 2 0 0 2 2 2 0 BUD22 zf-C2H2 PF00096.21 EMD69356.1 - 0.0023 18.1 10.1 0.014 15.7 0.8 2.9 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69356.1 - 0.085 13.2 5.5 1.1 9.6 0.6 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C3H1 PF10650.4 EMD69356.1 - 0.41 10.1 3.3 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 Putative zinc-finger domain Clr5 PF14420.1 EMD69357.1 - 5.1e-16 58.3 0.4 9.5e-16 57.4 0.3 1.5 1 0 0 1 1 1 1 Clr5 domain MRP-S27 PF10037.4 EMD69357.1 - 0.027 13.4 0.6 0.032 13.1 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 YebF PF13995.1 EMD69357.1 - 0.23 11.4 1.6 0.38 10.7 0.5 1.7 1 1 1 2 2 2 0 YebF-like protein PaaSYMP PF14738.1 EMD69357.1 - 0.41 10.3 6.6 1.3 8.7 1.5 2.1 1 1 1 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 TPR_12 PF13424.1 EMD69358.1 - 8.6e-56 185.8 8.1 4.8e-22 77.6 0.0 2.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMD69358.1 - 3.3e-43 144.4 10.8 3.4e-12 45.8 0.1 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69358.1 - 2e-17 62.6 1.9 2.4e-07 30.2 0.0 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMD69358.1 - 3.8e-17 61.0 1.1 0.00019 20.8 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69358.1 - 1.2e-14 52.8 7.2 0.00012 21.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD69358.1 - 1.1e-10 41.1 6.3 0.0086 16.6 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69358.1 - 1.2e-10 40.5 5.7 0.022 14.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69358.1 - 5.1e-10 39.7 6.7 2.8e-05 24.6 0.4 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.9 EMD69358.1 - 4.2e-08 32.8 5.1 0.32 11.5 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69358.1 - 2.7e-06 26.7 1.1 0.81 9.6 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMD69358.1 - 9.4e-06 25.4 1.6 1.6 9.1 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMD69358.1 - 4.7e-05 23.6 0.8 0.019 15.3 0.0 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat Atu4866 PF11512.3 EMD69358.1 - 0.00034 20.2 1.5 1.1 9.0 0.0 3.1 2 1 1 3 3 3 2 Agrobacterium tumefaciens protein Atu4866 TPR_6 PF13174.1 EMD69358.1 - 0.00041 20.6 6.4 29 5.4 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PspB PF06667.7 EMD69358.1 - 0.0005 19.9 0.9 1.5 8.8 0.0 3.1 3 0 0 3 3 3 1 Phage shock protein B DUF1925 PF09094.6 EMD69358.1 - 0.0017 18.3 0.1 0.44 10.5 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1925) Apc3 PF12895.2 EMD69358.1 - 0.0028 17.7 0.1 0.1 12.7 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EMD69358.1 - 0.014 15.2 0.5 8.4 6.6 0.0 3.2 3 0 0 3 3 3 0 PPR repeat Phage_int_SAM_4 PF13495.1 EMD69358.1 - 0.08 13.2 0.1 4.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain TPR_9 PF13371.1 EMD69358.1 - 0.48 10.3 3.5 2.2 8.1 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1897 PF09005.5 EMD69358.1 - 1 8.8 4.5 15 5.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Esterase_phd PF10503.4 EMD69360.1 - 7.8e-23 80.8 0.6 1.1e-22 80.4 0.4 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMD69360.1 - 1.8e-09 37.1 0.1 2.7e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD69360.1 - 6e-07 29.3 0.1 8.1e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMD69360.1 - 0.00015 21.7 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EMD69360.1 - 0.0011 18.7 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EMD69360.1 - 0.0039 16.7 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMD69360.1 - 0.0075 15.7 0.2 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.23 EMD69360.1 - 0.032 12.9 1.6 0.051 12.2 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.8 EMD69360.1 - 0.035 13.6 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Clat_adaptor_s PF01217.15 EMD69361.1 - 6e-42 142.7 0.1 1.9e-41 141.1 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EMD69362.1 - 3.1e-29 100.9 0.0 4e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 EMD69363.1 - 1.5e-21 75.6 3.1 1.8e-21 75.3 2.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EMD69363.1 - 0.051 13.5 0.3 0.087 12.7 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-TFIIB PF13453.1 EMD69363.1 - 0.74 9.0 4.1 1.3 8.2 1.2 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger Sec6 PF06046.8 EMD69364.1 - 2.5e-159 531.0 2.4 2.5e-159 531.0 1.7 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 AAA_13 PF13166.1 EMD69364.1 - 0.016 13.7 6.6 0.015 13.8 3.6 1.6 1 1 0 1 1 1 0 AAA domain DELLA PF12041.3 EMD69364.1 - 0.069 12.8 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DASH_Duo1 PF08651.5 EMD69364.1 - 0.12 11.9 2.9 0.41 10.2 0.3 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 YjcZ PF13990.1 EMD69364.1 - 0.18 10.9 3.5 1.1 8.3 0.9 2.5 2 0 0 2 2 2 0 YjcZ-like protein MutS_III PF05192.13 EMD69364.1 - 1.2 8.9 4.0 13 5.4 1.7 3.1 2 1 0 2 2 2 0 MutS domain III Retrotrans_gag PF03732.12 EMD69364.1 - 7.8 6.6 8.2 4.1 7.5 0.1 4.3 4 1 1 5 5 5 0 Retrotransposon gag protein Atrophin-1 PF03154.10 EMD69365.1 - 4.7 5.2 11.4 5.2 5.0 7.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family Abhydrolase_4 PF08386.5 EMD69366.1 - 1.5e-17 63.3 0.0 3.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMD69366.1 - 8.4e-15 54.9 0.5 1.3e-14 54.3 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMD69366.1 - 3.2e-07 30.4 1.0 7.4e-07 29.2 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Auxin_BP PF02041.11 EMD69366.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein TPR_10 PF13374.1 EMD69368.1 - 1.6e-142 459.9 0.2 8.1e-14 51.0 0.0 12.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 EMD69368.1 - 2.7e-133 434.1 8.6 6.2e-15 54.9 0.0 8.9 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69368.1 - 5.8e-41 135.0 10.8 0.003 17.2 0.0 11.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69368.1 - 3.7e-25 86.4 0.4 0.084 12.5 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69368.1 - 7.3e-25 84.8 2.5 0.078 12.9 0.0 11.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMD69368.1 - 1.4e-23 81.0 6.2 0.33 11.2 0.0 10.5 10 0 0 10 10 9 6 Tetratricopeptide repeat HET PF06985.6 EMD69368.1 - 2.5e-22 79.5 9.7 2.1e-20 73.2 6.0 3.5 2 1 0 2 2 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 EMD69368.1 - 3.4e-22 77.8 0.1 7e-05 22.3 0.0 6.6 2 1 7 9 9 9 8 TPR repeat TPR_19 PF14559.1 EMD69368.1 - 2.3e-20 72.6 0.0 0.011 15.9 0.0 9.3 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69368.1 - 1.3e-19 70.2 0.1 0.0087 16.7 0.0 8.3 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 EMD69368.1 - 7.6e-18 63.0 0.0 1.5 9.4 0.0 9.5 9 0 0 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD69368.1 - 4.3e-15 55.6 0.6 0.033 14.3 0.0 7.4 2 2 7 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMD69368.1 - 5.1e-15 54.0 2.1 1.2 9.0 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat NB-ARC PF00931.17 EMD69368.1 - 2.6e-14 52.7 0.7 3.3e-13 49.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PPR PF01535.15 EMD69368.1 - 4.8e-12 44.9 1.9 0.69 10.0 0.0 9.5 10 0 0 10 10 10 1 PPR repeat TPR_14 PF13428.1 EMD69368.1 - 5.8e-11 42.0 12.2 4.6 8.1 0.0 10.8 10 2 2 12 12 10 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMD69368.1 - 5.4e-08 32.8 8.3 12 6.1 0.0 9.4 2 1 10 12 12 11 0 Tetratricopeptide repeat AAA_16 PF13191.1 EMD69368.1 - 2.7e-06 27.5 0.1 2e-05 24.6 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain TPR_6 PF13174.1 EMD69368.1 - 4.2e-06 26.8 12.9 9.5 6.9 0.0 9.5 10 0 0 10 10 9 0 Tetratricopeptide repeat AAA_22 PF13401.1 EMD69368.1 - 1.6e-05 25.0 0.0 5.7e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain PPR_3 PF13812.1 EMD69368.1 - 0.00056 19.9 4.0 70 4.0 0.0 8.0 10 0 0 10 10 6 0 Pentatricopeptide repeat domain DUF2664 PF10867.3 EMD69368.1 - 0.0013 19.3 16.8 96 3.7 0.0 9.2 7 2 2 10 10 10 0 Protein of unknown function (DUF2664) PPR_2 PF13041.1 EMD69368.1 - 0.0073 16.2 0.8 25 4.9 0.0 5.6 6 0 0 6 6 5 0 PPR repeat family Arch_ATPase PF01637.13 EMD69368.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EMD69368.1 - 0.018 15.3 0.1 7.9 6.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 EMD69368.1 - 0.019 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMD69368.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_chlorC PF02043.12 EMD69368.1 - 0.076 12.8 0.0 17 5.3 0.0 3.3 2 1 1 3 3 3 0 Bacteriochlorophyll C binding protein ADH_N PF08240.7 EMD69370.1 - 1.6e-30 105.0 0.4 3e-30 104.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69370.1 - 2e-26 92.0 0.1 2.8e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CLTH PF10607.4 EMD69371.1 - 5.7e-31 107.1 0.0 7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EMD69371.1 - 1.1e-09 37.7 0.0 1.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 LisH OGFr_III PF04680.8 EMD69371.1 - 2 8.6 9.1 9.9 6.4 0.0 4.1 4 0 0 4 4 4 0 Opioid growth factor receptor repeat PRK PF00485.13 EMD69372.1 - 4.8e-58 195.9 0.0 6.6e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EMD69372.1 - 6.8e-40 136.4 0.0 1e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EMD69372.1 - 3.1e-09 37.7 0.0 6.3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EMD69372.1 - 7e-06 25.7 0.0 2.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EMD69372.1 - 0.00068 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD69372.1 - 0.0038 17.0 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD69372.1 - 0.0074 16.2 0.0 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EMD69372.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EMD69372.1 - 0.028 14.6 0.0 0.075 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EMD69372.1 - 0.035 12.8 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 EMD69372.1 - 0.053 13.2 0.0 1.1 8.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EMD69372.1 - 0.096 12.3 0.0 0.44 10.2 0.0 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EMD69372.1 - 0.11 12.8 0.9 0.22 11.7 0.3 1.7 2 0 0 2 2 2 0 ABC transporter Metallophos PF00149.23 EMD69373.1 - 1.2e-41 142.2 0.6 1.6e-41 141.9 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pmp3 PF01679.12 EMD69375.1 - 2.7e-18 65.3 2.1 3.7e-18 64.9 1.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Na_Ca_ex PF01699.19 EMD69376.1 - 2e-43 147.3 29.0 1.3e-21 76.6 5.3 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SNF2_N PF00176.18 EMD69377.1 - 6.1e-55 186.1 0.0 1.1e-54 185.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD69377.1 - 3.1e-09 36.5 0.0 6.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMD69377.1 - 0.00043 19.9 9.4 0.00089 18.9 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 EMD69377.1 - 0.0019 18.0 3.7 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.1 EMD69377.1 - 0.025 14.1 0.9 0.063 12.8 0.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 EMD69377.1 - 0.042 13.5 8.6 0.1 12.2 5.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMD69377.1 - 0.11 12.5 7.3 0.25 11.3 4.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD69377.1 - 0.86 9.3 10.9 2.7 7.7 7.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.13 EMD69378.1 - 9.9e-41 139.3 0.0 1.5e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69378.1 - 4.5e-09 36.0 8.3 1.2e-08 34.7 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 EMD69380.1 - 8.8e-50 169.5 0.0 1.5e-49 168.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rib_5-P_isom_A PF06026.9 EMD69381.1 - 2.1e-35 121.6 0.0 3.3e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EMD69381.1 - 0.0041 16.7 0.8 0.91 9.1 0.1 2.4 2 1 0 3 3 3 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 EMD69381.1 - 0.028 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain ThiF PF00899.16 EMD69382.1 - 1.6e-05 24.7 0.0 4.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 ThiF family zf-RING_5 PF14634.1 EMD69383.1 - 3e-07 30.0 17.9 1.8e-06 27.5 10.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMD69383.1 - 5.1e-06 26.4 15.6 5.1e-06 26.4 10.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD69383.1 - 5.5e-06 25.9 15.0 5.5e-06 25.9 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMD69383.1 - 6.9e-06 25.7 7.9 6.9e-06 25.7 5.5 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EMD69383.1 - 6.4e-05 22.7 17.8 8.8e-05 22.2 9.2 2.4 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.10 EMD69383.1 - 7.4e-05 22.6 0.1 0.00025 20.9 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-C3HC4_3 PF13920.1 EMD69383.1 - 7.5e-05 22.3 19.3 0.00017 21.1 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EMD69383.1 - 0.00012 21.4 0.0 0.00036 19.9 0.0 1.9 2 0 0 2 2 2 1 SAP domain zf-C3HC4_4 PF15227.1 EMD69383.1 - 0.0012 18.6 14.0 0.0012 18.6 9.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMD69383.1 - 0.0046 16.6 9.0 0.0046 16.6 6.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger PRP21_like_P PF12230.3 EMD69383.1 - 0.023 14.1 0.1 0.023 14.1 0.1 2.6 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Mob_synth_C PF06463.8 EMD69383.1 - 0.18 11.4 4.3 0.66 9.6 3.0 2.0 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 EMD69383.1 - 0.81 9.8 10.3 0.22 11.6 4.5 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EMD69383.1 - 1.5 8.4 16.4 1.8 8.2 8.7 2.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 EMD69383.1 - 2.8 7.5 6.9 0.64 9.5 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif MRI PF15325.1 EMD69383.1 - 8.8 7.3 13.9 0.53 11.2 0.8 3.1 2 1 1 3 3 3 0 Modulator of retrovirus infection DEAD PF00270.24 EMD69384.1 - 4.2e-40 136.9 0.2 6.8e-40 136.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMD69384.1 - 2.8e-21 75.1 0.0 6.7e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMD69384.1 - 4.1e-17 61.4 0.2 8.2e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMD69384.1 - 0.00073 19.4 1.8 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pantoate_ligase PF02569.10 EMD69385.1 - 9.3e-79 264.0 0.0 1.4e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Aldedh PF00171.17 EMD69387.1 - 1.3e-132 442.4 0.0 1.5e-132 442.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD69387.1 - 7.1e-07 28.2 0.0 3.1e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_DME PF15628.1 EMD69389.1 - 0.064 12.9 0.1 0.072 12.7 0.1 1.3 1 1 0 1 1 1 0 RRM in Demeter Fungal_trans PF04082.13 EMD69391.1 - 4.5e-31 107.6 0.0 2.9e-30 105.0 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69391.1 - 5.3e-08 32.6 9.3 1.1e-07 31.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EMD69391.1 - 6.9 5.9 15.8 20 4.4 11.0 1.9 1 0 0 1 1 1 0 Vta1 like DUF3648 PF12364.3 EMD69392.1 - 0.63 10.0 3.2 0.3 11.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) Nipped-B_C PF12830.2 EMD69394.1 - 1.5e-47 161.6 2.2 3.1e-46 157.3 0.2 3.2 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EMD69394.1 - 1.3e-10 40.9 0.4 6.2e-10 38.8 0.3 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EMD69394.1 - 0.00026 20.9 0.4 0.0037 17.1 0.0 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMD69394.1 - 0.0042 17.3 0.6 0.085 13.1 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EMD69394.1 - 0.0052 16.7 0.1 2 8.6 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EMD69395.1 - 9.4e-32 109.1 5.5 1.4e-15 57.3 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EMD69395.1 - 2.1e-21 74.1 2.1 0.0044 17.3 0.1 6.2 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EMD69395.1 - 1.1e-08 35.3 8.5 0.00098 19.5 0.0 4.9 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.17 EMD69395.1 - 2.4e-08 33.3 2.8 0.57 10.4 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.2 EMD69395.1 - 0.025 14.5 0.1 1 9.4 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EMD69395.1 - 0.082 12.7 1.4 15 5.5 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3533 PF12051.3 EMD69397.1 - 7.3e-116 387.0 20.2 8.4e-116 386.8 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Glyco_hydro_2_N PF02837.13 EMD69398.1 - 8.4e-29 100.2 1.2 2.4e-28 98.8 0.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMD69398.1 - 2.3e-14 53.0 0.0 7.3e-14 51.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMD69398.1 - 1.2e-08 35.3 0.1 5.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF2293 PF10056.4 EMD69399.1 - 9.4e-31 105.6 0.1 2.2e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_trans_4_2 PF13477.1 EMD69399.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF814 PF05670.8 EMD69400.1 - 1.1e-22 79.6 0.1 1.8e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Mgr1 PF08602.5 EMD69400.1 - 8 5.3 7.5 1.7 7.6 0.2 2.0 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Peptidase_S49_N PF08496.5 EMD69401.1 - 0.3 10.8 4.3 0.35 10.6 3.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.1 EMD69401.1 - 0.34 10.2 9.8 0.43 9.9 6.8 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Med19 PF10278.4 EMD69401.1 - 0.52 9.9 9.0 0.66 9.6 6.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 EMD69401.1 - 1.7 7.7 6.4 2.1 7.4 4.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) MARVEL PF01284.18 EMD69402.1 - 0.11 12.3 16.2 0.29 10.9 11.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain Amidase PF01425.16 EMD69403.1 - 2.6e-94 316.5 0.0 3.2e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Amidase GFA PF04828.9 EMD69404.1 - 1.8e-11 43.8 0.5 1.8e-11 43.8 0.3 2.0 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NCD3G PF07562.9 EMD69404.1 - 2.5 7.8 9.0 0.66 9.7 0.4 2.2 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-C3HC4_3 PF13920.1 EMD69404.1 - 4.6 7.0 10.3 4.9 6.9 1.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YyzF PF14116.1 EMD69404.1 - 6.8 6.7 8.2 2.8 7.9 0.6 2.2 2 0 0 2 2 2 0 YyzF-like protein GFA PF04828.9 EMD69405.1 - 0.00018 21.3 0.0 0.00042 20.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PMSR PF01625.16 EMD69406.1 - 6.8e-60 201.4 0.2 8e-60 201.2 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4360 PF14273.1 EMD69407.1 - 9.8e-67 224.1 5.3 1.1e-66 223.9 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Kinesin PF00225.18 EMD69408.1 - 5e-117 390.3 0.1 6.7e-117 389.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain ADH_N PF08240.7 EMD69409.1 - 1e-05 25.2 0.7 2.5e-05 23.9 0.1 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69409.1 - 0.0003 20.3 0.5 0.00063 19.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NPCBM_assoc PF10633.4 EMD69409.1 - 0.5 10.4 2.4 3 7.9 0.0 3.0 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Bac_rhamnosid PF05592.6 EMD69410.1 - 3.5e-34 117.8 0.8 7.7e-30 103.5 0.5 2.6 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EMD69410.1 - 0.001 17.8 0.6 0.0016 17.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 NUDIX PF00293.23 EMD69411.1 - 4.4e-15 55.5 0.0 4.9e-12 45.6 0.0 2.9 1 1 1 2 2 2 2 NUDIX domain IMPDH PF00478.20 EMD69412.1 - 5.8e-132 439.8 2.3 6.9e-132 439.5 1.6 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EMD69412.1 - 1.8e-16 59.6 0.0 3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EMD69412.1 - 1.7e-06 27.4 7.3 0.022 13.9 4.5 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EMD69412.1 - 1.4e-05 24.1 0.3 3.8e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EMD69412.1 - 0.0062 15.8 4.5 0.01 15.0 1.1 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EMD69412.1 - 0.029 13.4 0.9 0.063 12.3 0.2 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PK PF00224.16 EMD69412.1 - 0.04 12.5 0.0 0.12 11.0 0.0 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain DUF1273 PF06908.6 EMD69412.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) RasGAP_C PF03836.10 EMD69413.1 - 7.9e-45 152.0 4.0 2.8e-44 150.2 2.8 2.1 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EMD69413.1 - 2.8e-39 134.8 0.0 6.3e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EMD69413.1 - 4.4e-14 50.6 58.9 0.012 15.1 0.4 14.7 15 0 0 15 15 15 9 IQ calmodulin-binding motif CH PF00307.26 EMD69413.1 - 1.1e-07 31.7 0.0 5.2e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 EMD69414.1 - 2e-09 36.6 25.8 2.7e-09 36.2 17.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily LicD PF04991.8 EMD69415.1 - 1.5e-34 119.8 6.0 3.3e-34 118.7 3.3 2.2 2 1 0 2 2 2 1 LicD family DUF3405 PF11885.3 EMD69416.1 - 2.3e-192 639.6 18.8 6.8e-192 638.1 13.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) tRNA-synt_2d PF01409.15 EMD69417.1 - 5.8e-85 284.4 0.0 7.5e-85 284.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EMD69417.1 - 1.5e-07 30.5 0.1 0.00038 19.3 0.0 3.4 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMD69417.1 - 0.0008 19.0 0.0 0.0048 16.5 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EMD69417.1 - 0.1 11.6 0.2 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Tim17 PF02466.14 EMD69418.1 - 0.039 14.0 2.7 1.1 9.2 0.3 2.7 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family NmrA PF05368.8 EMD69420.1 - 6.3e-35 120.5 0.0 7.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD69420.1 - 5.1e-08 33.1 0.0 7.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding MLIP PF15274.1 EMD69420.1 - 0.52 9.7 2.4 0.89 8.9 1.6 1.4 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Zn_clus PF00172.13 EMD69421.1 - 8.5e-08 31.9 11.5 1.4e-07 31.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD69421.1 - 1.4e-05 24.1 0.0 1.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain ThiS PF02597.15 EMD69422.1 - 1.1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 ThiS family RNB PF00773.14 EMD69423.1 - 2.8e-58 197.7 0.0 1.5e-57 195.3 0.0 2.0 2 0 0 2 2 2 1 RNB domain Fungal_trans PF04082.13 EMD69425.1 - 1.5e-21 76.4 0.0 3.4e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69425.1 - 2e-05 24.3 11.1 4.3e-05 23.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EMD69426.1 - 6.4e-18 65.5 0.0 2.4e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD69426.1 - 3.8e-11 42.8 0.0 1.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMD69426.1 - 4.6e-11 41.6 0.2 1.8e-09 36.3 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EMD69426.1 - 3.6e-06 26.8 0.0 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD69426.1 - 2.4e-05 23.4 0.0 0.28 10.0 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMD69426.1 - 0.053 12.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase SH3_6 PF12913.2 EMD69427.1 - 0.031 13.5 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type Aldedh PF00171.17 EMD69428.1 - 3.1e-162 540.0 0.1 3.5e-162 539.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD69428.1 - 0.0012 17.6 0.0 0.0025 16.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMD69428.1 - 0.0046 16.1 0.0 0.039 13.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) adh_short PF00106.20 EMD69429.1 - 4.1e-15 56.1 0.0 1.9e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69429.1 - 8.5e-05 22.4 0.4 0.00081 19.2 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69429.1 - 0.00057 19.6 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD69429.1 - 0.0042 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMD69429.1 - 0.039 12.9 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EMD69429.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EMD69429.1 - 0.081 11.6 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 EMD69429.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EMD69430.1 - 3.8e-28 98.4 0.3 4.9e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69430.1 - 1.4e-26 93.7 0.0 1.8e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69430.1 - 5.3e-13 49.0 0.1 7.8e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD69430.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMD69430.1 - 0.06 13.1 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMP-binding PF00501.23 EMD69431.1 - 1.8e-78 263.8 0.0 2.3e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD69431.1 - 1.8e-10 41.5 0.4 6.7e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 EMD69432.1 - 8.2e-22 77.1 0.0 1.3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD69432.1 - 5.4e-18 64.7 0.4 9.2e-18 64.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EMD69432.1 - 0.0014 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EMD69432.1 - 0.0073 16.1 0.3 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 ThiF family CMAS PF02353.15 EMD69432.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AlaDh_PNT_C PF01262.16 EMD69432.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 EMD69432.1 - 0.068 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 EMD69432.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMD69432.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_3 PF07859.8 EMD69433.1 - 9.7e-46 155.9 0.2 1.2e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMD69433.1 - 9.8e-07 27.8 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMD69433.1 - 0.00048 19.9 0.2 0.00065 19.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMD69433.1 - 0.0039 16.6 0.0 0.038 13.4 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Acyl-CoA_dh_1 PF00441.19 EMD69434.1 - 2.3e-24 86.2 0.2 3.9e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMD69434.1 - 1.9e-10 41.3 0.0 4.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD69434.1 - 5.7e-08 33.0 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMD69434.1 - 0.0035 16.8 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RNA_pol_Rbc25 PF08292.7 EMD69434.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 adh_short PF00106.20 EMD69435.1 - 4.8e-26 91.6 0.1 6.1e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69435.1 - 1.4e-23 83.8 0.1 1.8e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69435.1 - 2.8e-09 36.8 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD69435.1 - 8e-05 22.1 0.2 0.00018 21.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.16 EMD69435.1 - 9.2e-05 22.2 0.1 0.0003 20.6 0.0 1.9 1 1 1 2 2 2 1 ThiF family Ldh_1_N PF00056.18 EMD69435.1 - 0.014 15.2 0.3 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EMD69436.1 - 2.3e-19 70.2 0.0 7.7e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD69436.1 - 4.5e-13 48.2 0.0 3.2e-10 38.8 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMD69436.1 - 1e-11 44.6 0.0 2.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD69436.1 - 2.2e-05 24.2 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD69436.1 - 4.6e-05 22.5 0.0 0.055 12.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMD69436.1 - 0.0015 18.4 0.0 0.14 12.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD69436.1 - 0.073 11.5 0.0 0.14 10.5 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EMD69436.1 - 0.079 11.8 0.0 0.48 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Dioxygenase_C PF00775.16 EMD69438.1 - 1.7e-08 33.9 0.1 3.4e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 Dioxygenase Bax1-I PF01027.15 EMD69440.1 - 1.5e-32 112.9 9.9 2e-32 112.4 6.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EMD69440.1 - 0.85 9.7 7.5 4.6 7.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) MerC PF03203.9 EMD69440.1 - 2 8.8 10.4 0.66 10.3 0.8 2.6 2 1 1 3 3 3 0 MerC mercury resistance protein Sugar_tr PF00083.19 EMD69442.1 - 2.5e-33 115.3 25.0 6.1e-33 114.0 17.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69442.1 - 5.5e-32 110.8 46.7 1.1e-29 103.3 19.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.7 EMD69442.1 - 0.031 14.0 0.1 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) PIRT PF15099.1 EMD69442.1 - 0.078 12.1 2.0 0.13 11.4 0.2 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family HeLo PF14479.1 EMD69443.1 - 5.2e-33 114.5 0.1 9.1e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 EMD69443.1 - 6.8e-09 35.6 0.2 2.2e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EMD69443.1 - 6.1e-07 29.6 0.0 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMD69443.1 - 0.00093 18.7 0.1 0.0087 15.5 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EMD69443.1 - 0.00097 19.1 0.2 0.016 15.2 0.0 3.0 4 1 0 4 4 3 1 AAA ATPase domain AAA_17 PF13207.1 EMD69443.1 - 0.0015 19.3 0.1 0.014 16.2 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EMD69443.1 - 0.0058 16.9 0.0 0.022 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EMD69443.1 - 0.012 15.7 0.1 0.03 14.5 0.1 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EMD69443.1 - 0.026 14.8 0.1 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EMD69443.1 - 0.041 13.7 0.5 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMD69443.1 - 0.046 13.2 0.3 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMD69443.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EMD69443.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EMD69443.1 - 0.068 13.3 0.0 0.59 10.3 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMD69443.1 - 0.12 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Mononeg_mRNAcap PF14318.1 EMD69443.1 - 0.13 11.2 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V cNMP_binding PF00027.24 EMD69444.1 - 3.6e-32 110.0 0.0 1.6e-18 66.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EMD69444.1 - 1.8e-12 45.9 3.2 1.8 8.9 0.0 8.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.1 EMD69444.1 - 4.9e-07 29.4 0.0 0.0021 17.7 0.1 3.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EMD69444.1 - 4e-05 23.1 0.0 1.8 8.2 0.0 5.1 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMD69444.1 - 0.00078 19.1 8.6 42 4.7 0.2 7.9 5 3 1 6 6 6 0 Leucine Rich Repeat F-box-like PF12937.2 EMD69444.1 - 0.0013 18.3 0.7 0.0059 16.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD69444.1 - 0.0073 15.9 0.3 0.0073 15.9 0.2 3.2 3 0 0 3 3 3 1 F-box domain Ste50p-SAM PF09235.5 EMD69444.1 - 0.043 13.8 0.1 6 6.9 0.0 3.3 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EMD69444.1 - 0.067 13.4 13.5 29 5.4 0.0 7.1 8 0 0 8 8 8 0 Leucine rich repeat Rick_17kDa_Anti PF05433.10 EMD69445.1 - 5.3e-06 25.9 13.5 1.2e-05 24.8 9.4 1.6 1 1 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMD69445.1 - 0.002 17.7 6.5 0.004 16.8 4.5 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EMD69445.1 - 0.013 14.9 9.5 0.022 14.2 6.6 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF533 PF04391.7 EMD69445.1 - 0.046 13.1 2.5 0.08 12.3 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TraT PF05818.7 EMD69445.1 - 0.086 12.2 1.8 0.13 11.7 1.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 EMD69445.1 - 0.22 11.6 3.9 0.37 10.9 2.7 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 EMD69445.1 - 0.31 10.7 13.3 0.19 11.3 3.3 2.0 1 1 1 2 2 2 0 Glycine zipper Ribonucleas_3_3 PF14622.1 EMD69446.1 - 1.2e-08 34.9 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD69446.1 - 1.9e-07 31.5 0.0 4.8e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMD69447.1 - 5.8e-11 42.4 0.0 9.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMD69447.1 - 1.4e-09 38.3 0.0 5e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain RNase_PH PF01138.16 EMD69448.1 - 1.2e-36 125.8 0.1 2.1e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMD69448.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 SNF2_N PF00176.18 EMD69449.1 - 1.2e-56 191.6 0.1 1.8e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EMD69449.1 - 8.7e-18 63.9 0.1 3.3e-17 62.1 0.1 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EMD69449.1 - 2.1e-15 56.3 0.0 7.1e-13 48.2 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMD69449.1 - 7.2e-06 25.9 0.9 3.4e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMD69449.1 - 6.8e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase p450 PF00067.17 EMD69450.1 - 1.6e-55 188.4 0.0 3e-55 187.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 PSI_8 PF00796.13 EMD69450.1 - 0.061 12.9 2.0 0.12 11.9 1.4 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Glyco_hydro_3 PF00933.16 EMD69451.1 - 8e-48 162.9 0.0 1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMD69451.1 - 3.5e-08 33.2 0.7 2.4e-06 27.2 0.0 2.9 1 1 1 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_28 PF00295.12 EMD69453.1 - 1.7e-52 178.4 12.3 5.2e-52 176.8 8.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EMD69453.1 - 0.00052 19.8 11.6 0.00052 19.8 8.0 2.7 2 1 1 3 3 3 1 Right handed beta helix region Fork_head PF00250.13 EMD69454.1 - 5.8e-19 67.9 0.1 1.3e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EMD69455.1 - 8.4e-63 211.0 5.7 8.4e-63 211.0 4.0 1.9 1 1 1 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EMD69455.1 - 7e-56 187.2 4.7 1.2e-55 186.4 3.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Chorion_2 PF03964.10 EMD69455.1 - 0.013 16.0 0.1 0.013 16.0 0.1 2.5 2 0 0 2 2 2 0 Chorion family 2 23S_rRNA_IVP PF05635.6 EMD69455.1 - 0.018 14.9 0.4 0.044 13.7 0.2 1.7 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein YgaB PF14182.1 EMD69455.1 - 0.32 11.2 3.2 7 6.9 0.3 2.9 2 0 0 2 2 2 0 YgaB-like protein XLF PF09302.6 EMD69456.1 - 3.8e-27 95.1 1.1 6.7e-27 94.3 0.7 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) TPR_11 PF13414.1 EMD69459.1 - 3.4e-10 39.4 3.7 4.1e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 EMD69459.1 - 1.9e-09 38.0 1.1 7.1e-08 32.9 0.0 3.4 3 1 0 3 3 3 1 SET domain TPR_2 PF07719.12 EMD69459.1 - 7.7e-06 25.4 2.0 0.005 16.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69459.1 - 0.0017 18.9 2.7 0.31 11.7 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69459.1 - 0.0053 16.3 0.3 0.26 10.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69459.1 - 0.075 12.8 0.4 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMD69459.1 - 0.088 12.7 1.2 0.25 11.2 0.5 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMD69459.1 - 0.8 10.3 5.4 0.18 12.3 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EMD69460.1 - 4e-07 29.6 0.0 6.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Transketolase_N PF00456.16 EMD69461.1 - 1.2e-113 379.3 0.0 1.8e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMD69461.1 - 4.9e-44 149.9 0.1 9.5e-44 148.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMD69461.1 - 1.6e-08 34.5 0.0 4.2e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EMD69461.1 - 1.1e-07 31.0 0.0 3.4e-06 26.2 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EMD69461.1 - 3.5e-05 22.6 0.0 7.9e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.7 EMD69462.1 - 1.4e-28 98.7 2.8 2.2e-28 98.1 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69462.1 - 3e-12 46.2 0.0 5.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMD69462.1 - 0.016 15.2 0.4 0.053 13.5 0.1 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PGAP1 PF07819.8 EMD69463.1 - 0.00013 21.6 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 2 PGAP1-like protein Malic_M PF03949.10 EMD69465.1 - 3.4e-86 288.9 0.0 4.9e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMD69465.1 - 3e-67 225.7 0.0 4.6e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RVP_2 PF08284.6 EMD69470.1 - 0.0078 16.1 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Seryl_tRNA_N PF02403.17 EMD69471.1 - 0.023 14.7 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PRTase_3 PF15610.1 EMD69473.1 - 2.6e-75 252.8 0.3 3.1e-75 252.5 0.2 1.1 1 0 0 1 1 1 1 PRTase ComF-like p450 PF00067.17 EMD69475.1 - 1.6e-46 158.7 0.0 2.2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2CSK_N PF08521.5 EMD69475.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal HTH_Tnp_Tc3_2 PF01498.13 EMD69476.1 - 3.2e-18 65.5 1.1 4.9e-18 64.9 0.3 1.7 2 0 0 2 2 1 1 Transposase HTH_32 PF13565.1 EMD69476.1 - 1.7e-08 35.1 2.8 5.3e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EMD69476.1 - 3e-08 33.7 2.4 1.4e-07 31.6 0.2 2.5 1 1 1 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.11 EMD69476.1 - 8.3e-07 28.2 0.2 0.035 13.4 0.0 2.8 2 1 0 2 2 2 2 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EMD69476.1 - 9.5e-06 24.9 0.3 0.00045 19.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 EMD69476.1 - 1e-05 25.0 0.0 0.0015 18.0 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 EMD69476.1 - 0.0002 20.2 0.1 0.00025 19.9 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain HTH_24 PF13412.1 EMD69476.1 - 0.00093 18.5 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_33 PF13592.1 EMD69476.1 - 0.003 17.0 0.1 0.0092 15.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 EMD69476.1 - 0.009 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 HTH-like domain UB2H PF14814.1 EMD69476.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain CENP-B_N PF04218.8 EMD69476.1 - 0.03 13.7 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Glyco_hydro_43 PF04616.9 EMD69478.1 - 2.4e-72 243.4 0.1 3.1e-72 243.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 EMD69479.1 - 1.5e-77 261.1 18.4 1.8e-77 260.8 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69479.1 - 2.8e-25 88.8 22.4 1.8e-17 63.1 3.3 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily HET PF06985.6 EMD69480.1 - 1.7e-36 125.3 2.3 3.2e-36 124.5 1.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S28 PF05577.7 EMD69481.1 - 3.1e-47 161.1 0.0 7.3e-47 159.9 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EMD69481.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_7 PF13508.1 EMD69482.1 - 0.0002 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD69482.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMD69482.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMD69482.1 - 0.0016 18.5 0.1 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EMD69482.1 - 0.05 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EMD69482.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase 6PGD PF00393.14 EMD69483.1 - 5.2e-67 226.0 0.0 6.5e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMD69483.1 - 8.3e-25 87.5 0.0 1.6e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD69483.1 - 0.0012 18.9 0.2 0.003 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 EMD69484.1 - 2.3e-16 59.1 0.0 3.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD69484.1 - 5.7e-13 48.6 0.0 8.5e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD69484.1 - 7.1e-07 28.9 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMD69484.1 - 0.039 13.7 0.1 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_76 PF03663.9 EMD69486.1 - 1.3e-21 77.4 7.5 2.6e-15 56.7 0.1 3.4 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 DUF4245 PF14030.1 EMD69486.1 - 0.059 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) IBN_N PF03810.14 EMD69487.1 - 3.8e-16 58.7 0.5 2.5e-15 56.1 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMD69487.1 - 0.0066 16.3 0.1 0.0066 16.3 0.1 3.0 4 0 0 4 4 4 1 Exportin 1-like protein Pex2_Pex12 PF04757.9 EMD69488.1 - 1.4e-40 139.1 3.3 2.1e-40 138.5 2.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EMD69488.1 - 0.0028 17.4 5.0 0.0054 16.5 3.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMD69488.1 - 0.39 10.4 2.4 0.28 10.9 0.2 1.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMD69488.1 - 1.6 8.8 8.8 0.63 10.1 2.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EMD69489.1 - 0.00045 20.3 2.8 0.019 15.2 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69489.1 - 0.00062 19.9 1.3 0.044 14.1 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD69489.1 - 0.039 14.0 1.8 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMD69489.1 - 0.099 12.7 1.3 2.4 8.3 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMD69489.1 - 0.16 11.9 2.8 4.2 7.4 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Peptidase_C12 PF01088.16 EMD69490.1 - 6e-57 192.2 0.0 6.9e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 F-box-like PF12937.2 EMD69491.1 - 0.00018 21.1 0.0 0.00062 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EMD69492.1 - 3.2e-06 26.7 0.2 9.1e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMD69492.1 - 3.4e-06 26.5 0.4 6.5e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 F-box domain Utp12 PF04003.7 EMD69492.1 - 0.01 15.7 0.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family Aldedh PF00171.17 EMD69493.1 - 6.6e-135 450.0 0.4 7.8e-135 449.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD69493.1 - 0.00022 20.0 0.0 0.00035 19.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MetW PF07021.7 EMD69493.1 - 0.05 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fungal_trans PF04082.13 EMD69495.1 - 4.2e-15 55.3 0.0 8.9e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMD69496.1 - 7.6e-34 116.9 23.5 7.6e-34 116.9 16.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.3 EMD69496.1 - 0.25 11.4 2.0 0.41 10.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) NIF PF03031.13 EMD69498.1 - 7.5e-38 129.6 0.0 1.4e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_47 PF01532.15 EMD69499.1 - 6.6e-136 453.5 0.0 8.1e-136 453.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M36 PF02128.10 EMD69501.1 - 2.6e-149 497.1 4.4 3.3e-149 496.8 3.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EMD69501.1 - 1.6e-10 40.2 0.1 6.6e-10 38.3 0.1 2.0 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EMD69501.1 - 3.1e-05 23.7 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain ER_lumen_recept PF00810.13 EMD69502.1 - 5.3e-33 114.5 12.7 7.3e-33 114.1 8.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF3816 PF12822.2 EMD69502.1 - 0.34 10.7 6.5 0.52 10.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Myb_DNA-bind_6 PF13921.1 EMD69503.1 - 0.0065 16.5 6.2 0.014 15.4 0.3 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain CAF-1_p150 PF11600.3 EMD69503.1 - 0.02 14.2 4.2 0.047 13.0 2.9 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myb_DNA-binding PF00249.26 EMD69503.1 - 0.19 11.8 2.9 0.99 9.5 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Aldo_ket_red PF00248.16 EMD69505.1 - 4.6e-46 156.9 0.0 6.4e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DJ-1_PfpI PF01965.19 EMD69506.1 - 2.9e-24 85.2 0.0 4.7e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.9 EMD69506.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI_N PF13587.1 EMD69506.1 - 0.018 14.5 0.0 0.055 13.0 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Hydantoinase_A PF01968.13 EMD69507.1 - 6.4e-76 255.2 7.3 4.7e-75 252.3 1.5 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EMD69507.1 - 1.4e-65 221.4 0.0 3.7e-65 220.1 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EMD69507.1 - 1.8e-48 164.3 2.7 7.9e-46 155.7 0.0 3.6 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EMD69507.1 - 0.0013 18.0 0.7 0.091 12.0 0.1 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family p450 PF00067.17 EMD69510.1 - 3.7e-70 236.7 0.0 5e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMD69510.1 - 1.6e-26 93.1 0.1 4.5e-26 91.6 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD69510.1 - 2.1e-18 66.7 0.0 4.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMD69510.1 - 7.9e-13 48.9 0.0 3.2e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EMD69510.1 - 0.025 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain NAD_binding_6 PF08030.7 EMD69510.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Pro_dh PF01619.13 EMD69511.1 - 1.1e-30 106.7 1.0 1.2e-30 106.5 0.1 1.5 2 0 0 2 2 2 1 Proline dehydrogenase TP_methylase PF00590.15 EMD69511.1 - 0.021 14.5 0.2 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases ADH_N PF08240.7 EMD69513.1 - 2.1e-23 82.1 0.4 2.1e-23 82.1 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69513.1 - 1.5e-15 56.9 0.2 2.3e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD69513.1 - 2.2e-05 25.3 0.1 5e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EMD69513.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EMD69513.1 - 0.021 14.3 0.4 0.041 13.4 0.1 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMD69513.1 - 0.088 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EMD69514.1 - 1e-07 31.5 0.1 9.8e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EMD69514.1 - 0.032 13.2 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.1 EMD69514.1 - 0.044 13.7 0.0 0.51 10.3 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding Thi4 PF01946.12 EMD69514.1 - 0.045 12.8 0.1 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EMD69514.1 - 0.058 13.4 0.5 0.13 12.3 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD69514.1 - 0.18 10.6 0.6 0.36 9.6 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HTH_23 PF13384.1 EMD69515.1 - 8.8e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EMD69515.1 - 2.8e-05 24.2 0.0 3.7e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EMD69515.1 - 0.0081 15.3 0.1 0.072 12.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EMD69515.1 - 0.021 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.18 EMD69515.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein HTH_32 PF13565.1 EMD69515.1 - 0.076 13.8 0.7 0.93 10.3 0.2 2.0 1 1 1 2 2 2 0 Homeodomain-like domain Mito_carr PF00153.22 EMD69516.1 - 8.3e-19 67.0 5.0 7.3e-14 51.2 0.5 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein AMP-binding PF00501.23 EMD69517.1 - 3.6e-48 164.0 0.0 5.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMD69517.1 - 0.00038 21.3 0.0 0.00083 20.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HMGL-like PF00682.14 EMD69518.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Acyl-CoA_dh_1 PF00441.19 EMD69519.1 - 5.4e-31 107.7 0.7 6.7e-31 107.4 0.5 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EMD69519.1 - 1.1e-13 51.5 0.4 1.7e-13 51.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans_2 PF11951.3 EMD69520.1 - 2.9e-11 42.5 4.0 2.9e-10 39.2 2.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69520.1 - 7.9e-07 28.8 11.1 1.5e-06 28.0 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suf PF05843.9 EMD69520.1 - 9.4 5.8 10.9 13 5.3 4.7 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) HET PF06985.6 EMD69521.1 - 3.5e-21 75.8 11.6 7.5e-20 71.5 6.0 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AIG2 PF06094.7 EMD69521.1 - 1.7e-07 31.6 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family DUF1664 PF07889.7 EMD69521.1 - 1.3 8.7 4.7 9.6 6.0 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EMD69522.1 - 1.6e-21 75.3 8.9 0.00079 19.2 0.3 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Acyltransferase PF01553.16 EMD69523.1 - 1.9e-17 62.9 0.0 4.1e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Adaptin_N PF01602.15 EMD69524.1 - 4e-101 338.9 0.0 5.7e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EMD69524.1 - 7.2e-09 35.8 10.1 5.9e-05 23.2 0.0 5.3 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EMD69524.1 - 3.1e-05 23.6 1.1 6.6 7.0 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat DUF3922 PF13059.1 EMD69524.1 - 0.087 13.0 0.1 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) HEAT_EZ PF13513.1 EMD69524.1 - 0.46 11.0 8.6 0.74 10.3 0.0 4.9 5 2 1 6 6 6 0 HEAT-like repeat Rho_GDI PF02115.12 EMD69525.1 - 2.9e-58 196.6 0.3 3.1e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 EMD69526.1 - 0.0044 16.6 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain tRNA_int_end_N2 PF12928.2 EMD69526.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term DUF1395 PF07160.7 EMD69526.1 - 0.31 10.4 4.5 0.51 9.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Ligase_CoA PF00549.14 EMD69527.1 - 4.1e-31 107.6 2.0 6e-15 55.1 0.3 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EMD69527.1 - 4.2e-17 62.4 1.9 8.4e-17 61.4 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EMD69527.1 - 1e-08 34.8 0.2 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 EMD69527.1 - 0.041 14.4 0.1 7.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_15 PF00723.16 EMD69528.1 - 3.2e-68 230.3 0.0 3.8e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_11 PF00457.12 EMD69529.1 - 1.8e-80 268.6 23.2 2.1e-80 268.3 16.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Aminotran_3 PF00202.16 EMD69530.1 - 6e-62 209.4 0.1 1.8e-54 184.8 0.0 2.4 1 1 1 2 2 2 2 Aminotransferase class-III SepQ PF06622.6 EMD69531.1 - 0.07 12.0 0.3 0.079 11.8 0.2 1.0 1 0 0 1 1 1 0 SepQ protein DUF1191 PF06697.7 EMD69532.1 - 0.0097 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EMD69532.1 - 0.01 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMD69532.1 - 3.2 7.4 5.4 12 5.5 3.8 1.8 1 1 0 1 1 1 0 TMEM154 protein family Cpn60_TCP1 PF00118.19 EMD69533.1 - 2.4e-143 478.2 15.8 2.8e-143 478.0 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.6 EMD69534.1 - 6.6e-23 80.4 0.2 1.5e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EMD69534.1 - 4.3e-19 68.7 0.0 6.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMD69534.1 - 6.7e-19 67.6 0.1 1.4e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Proteasom_Rpn13 PF04683.8 EMD69535.1 - 1.8e-28 98.4 0.0 3.1e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UCR_14kD PF02271.11 EMD69535.1 - 0.064 13.0 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribosomal_L6e PF01159.14 EMD69536.1 - 7e-37 125.9 0.2 7e-37 125.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.24 EMD69536.1 - 0.055 13.2 0.5 0.23 11.2 0.2 2.2 2 0 0 2 2 2 0 KOW motif FA_hydroxylase PF04116.8 EMD69537.1 - 2.1e-08 34.5 12.3 2.1e-08 34.5 8.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ADH_zinc_N PF00107.21 EMD69538.1 - 1.9e-33 114.8 0.0 5.4e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD69538.1 - 4e-15 56.8 0.0 7.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD69538.1 - 1.1e-10 41.2 0.0 9e-10 38.2 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EMD69538.1 - 0.0033 17.3 0.3 0.0099 15.8 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase DUF938 PF06080.7 EMD69538.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) HTH_AsnC-type PF13404.1 EMD69539.1 - 0.0017 17.8 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain Ndc1_Nup PF09531.5 EMD69539.1 - 0.0055 15.1 2.8 0.0078 14.6 2.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup HTH_24 PF13412.1 EMD69539.1 - 0.037 13.4 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Vps51 PF08700.6 EMD69540.1 - 3e-15 55.8 4.2 3e-15 55.8 2.9 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EMD69540.1 - 0.00065 19.5 0.8 0.00065 19.5 0.6 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Bacteriocin_IIc PF10439.4 EMD69540.1 - 0.0023 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Atg14 PF10186.4 EMD69540.1 - 0.039 12.8 10.3 0.007 15.3 4.1 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MAS20 PF02064.10 EMD69541.1 - 1.9e-22 79.4 0.9 5.2e-22 78.0 0.6 1.6 1 1 0 1 1 1 1 MAS20 protein import receptor DUF2328 PF10090.4 EMD69541.1 - 0.053 12.6 0.3 0.088 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) Ras PF00071.17 EMD69542.1 - 1.5e-59 199.9 0.5 2e-59 199.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD69542.1 - 1.6e-20 73.7 0.2 2.8e-20 72.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMD69542.1 - 9e-18 64.1 0.3 1.1e-17 63.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD69542.1 - 1e-07 31.6 0.1 4.7e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMD69542.1 - 3e-06 26.5 0.2 3.8e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMD69542.1 - 4.3e-06 26.0 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMD69542.1 - 9.1e-06 25.6 0.1 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMD69542.1 - 0.043 13.9 0.1 1.3 9.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMD69542.1 - 0.054 13.3 0.2 2.8 7.7 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EMD69542.1 - 0.078 12.6 0.1 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EMD69542.1 - 0.13 12.1 0.3 0.28 11.0 0.2 1.6 1 1 1 2 2 2 0 AAA domain Nop53 PF07767.6 EMD69543.1 - 1.5e-99 333.5 41.7 1.9e-99 333.3 28.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2937 PF11157.3 EMD69543.1 - 9 5.5 7.5 0.87 8.8 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SPX PF03105.14 EMD69543.1 - 9.3 5.9 20.9 8.7 6.0 13.8 1.3 1 1 0 1 1 1 0 SPX domain MFS_1 PF07690.11 EMD69544.1 - 8.2e-33 113.5 15.3 1.2e-32 112.9 9.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Syja_N PF02383.13 EMD69545.1 - 1.5e-92 309.7 0.7 2.4e-92 309.1 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Hexokinase_2 PF03727.11 EMD69546.1 - 8.1e-32 110.3 0.0 2.3e-30 105.5 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMD69546.1 - 1.5e-24 86.5 0.0 4.7e-24 84.8 0.0 1.8 1 1 0 1 1 1 1 Hexokinase Gly-zipper_OmpA PF13436.1 EMD69546.1 - 0.055 13.1 1.5 0.08 12.6 0.0 2.0 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain GILT PF03227.11 EMD69547.1 - 1.9e-11 43.7 0.0 3.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF2921 PF11145.3 EMD69547.1 - 0.059 11.0 0.0 0.066 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) DUF1681 PF07933.9 EMD69548.1 - 2e-56 189.9 0.0 3.2e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tyrosinase PF00264.15 EMD69549.1 - 4.7e-46 157.7 3.9 7.6e-46 157.0 2.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-RING_4 PF14570.1 EMD69549.1 - 3.2 7.4 5.2 0.52 9.9 0.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NADH5_C PF06455.6 EMD69550.1 - 0.34 10.2 9.5 0.15 11.4 2.8 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus HAD PF12710.2 EMD69551.1 - 2.3e-12 47.4 0.0 3.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMD69551.1 - 0.00066 18.9 0.1 0.7 9.0 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EMD69551.1 - 0.002 18.3 0.0 0.0073 16.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EMD69551.1 - 0.0046 16.3 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.6 EMD69552.1 - 2e-57 194.1 8.9 3.7e-57 193.2 6.2 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family DUF898 PF05987.8 EMD69552.1 - 0.11 11.4 0.3 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2564 PF10819.3 EMD69552.1 - 4.1 7.6 15.2 0.088 12.9 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) RNase_P_Rpp14 PF01900.14 EMD69553.1 - 1.3e-36 124.7 0.0 1.8e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Synaptobrevin PF00957.16 EMD69554.1 - 3.9e-31 106.5 0.1 5.5e-31 106.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMD69554.1 - 5.4e-16 57.9 0.0 9.4e-16 57.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 EMD69554.1 - 0.27 11.0 1.6 0.52 10.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) CPSase_L_D2 PF02786.12 EMD69555.1 - 4.7e-113 375.6 0.5 2.2e-82 275.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EMD69555.1 - 2e-46 157.8 0.0 4.9e-46 156.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EMD69555.1 - 3.1e-44 149.6 0.0 7.6e-44 148.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 EMD69555.1 - 8.9e-43 144.9 0.3 2.2e-42 143.7 0.1 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 EMD69555.1 - 1.9e-42 144.2 0.0 4.1e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EMD69555.1 - 2.4e-40 137.0 0.0 7e-19 67.9 0.0 3.0 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EMD69555.1 - 1.8e-38 131.8 0.2 6.6e-38 130.0 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EMD69555.1 - 8.6e-34 116.8 0.1 1.9e-20 73.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMD69555.1 - 1.1e-22 80.2 0.1 9e-11 41.0 0.0 4.2 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EMD69555.1 - 3.2e-20 71.8 0.0 2.1e-19 69.2 0.0 2.6 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EMD69555.1 - 3.1e-15 56.1 0.6 1.1e-07 31.4 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMD69555.1 - 1.6e-14 53.6 0.2 4e-06 26.2 0.0 3.0 4 0 0 4 4 4 2 ATP-grasp domain Peptidase_C26 PF07722.8 EMD69555.1 - 3.8e-07 29.7 0.2 2e-05 24.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EMD69555.1 - 3.5e-06 26.9 0.5 0.038 13.8 0.0 2.9 3 0 0 3 3 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EMD69555.1 - 0.00057 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EMD69555.1 - 0.0028 17.2 0.3 2.5 7.6 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ion_trans PF00520.26 EMD69557.1 - 1.7e-05 24.1 21.4 5.6e-05 22.4 14.6 2.0 1 1 0 1 1 1 1 Ion transport protein DUF605 PF04652.11 EMD69558.1 - 9.9 5.4 15.9 13 5.0 11.0 1.2 1 0 0 1 1 1 0 Vta1 like Rad60-SLD PF11976.3 EMD69559.1 - 9.9e-19 66.8 0.3 1.3e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMD69559.1 - 9.4e-09 34.5 0.1 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1903 PF08991.5 EMD69560.1 - 8.9e-24 83.4 9.6 1e-23 83.2 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EMD69560.1 - 0.00089 19.1 6.5 0.0016 18.2 4.5 1.6 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EMD69560.1 - 0.027 14.2 3.4 0.027 14.2 2.4 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Brr6_like_C_C PF10104.4 EMD69560.1 - 1.4 8.4 5.5 1.4 8.4 3.8 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Nup84_Nup100 PF04121.8 EMD69561.1 - 5.8e-58 196.1 8.8 3.9e-32 110.8 0.1 3.5 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF1295 PF06966.7 EMD69562.1 - 3.8e-30 104.9 0.1 5.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EMD69562.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EMD69562.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase ICMT PF04140.9 EMD69562.1 - 0.028 14.6 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Exo_endo_phos PF03372.18 EMD69563.1 - 6.4e-10 39.3 0.0 8.1e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribonuc_L-PSP PF01042.16 EMD69564.1 - 5.8e-13 48.6 0.0 9.5e-13 47.9 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Ketoacyl-synt_C PF02801.17 EMD69564.1 - 0.11 12.2 0.1 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Arginase PF00491.16 EMD69565.1 - 4.9e-77 258.9 1.1 5.9e-77 258.6 0.7 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMD69565.1 - 0.12 12.5 1.1 0.21 11.7 0.8 1.3 1 0 0 1 1 1 0 UPF0489 domain Cyt-b5 PF00173.23 EMD69566.1 - 3.7e-05 23.4 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 EMD69568.1 - 5.7e-65 214.8 1.0 1.5e-20 72.5 0.1 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD69568.1 - 1.4e-49 165.9 0.2 7.1e-15 54.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD69568.1 - 1.2e-27 95.5 0.6 9.5e-11 41.3 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 EMD69568.1 - 0.0024 17.8 13.7 0.0024 17.8 9.5 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Limkain-b1 PF11608.3 EMD69568.1 - 0.0031 17.2 4.6 0.026 14.2 0.5 4.0 4 0 0 4 4 4 1 Limkain b1 MFS_1 PF07690.11 EMD69569.1 - 1.7e-25 89.5 40.7 1.1e-17 63.8 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69569.1 - 3.9e-15 55.3 25.0 6.7e-14 51.3 17.3 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter OCIA PF07051.6 EMD69569.1 - 0.42 10.0 4.2 0.42 10.0 0.1 2.6 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) ABC_tran PF00005.22 EMD69571.1 - 1.5e-20 73.9 0.0 2.1e-10 41.0 0.0 2.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EMD69571.1 - 3.2e-09 37.1 0.0 0.0021 18.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EMD69571.1 - 0.00016 21.4 0.0 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EMD69571.1 - 0.071 12.6 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 EMD69571.1 - 0.11 10.9 0.0 0.21 9.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EMD69571.1 - 0.19 9.0 0.3 0.33 8.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EMD69571.1 - 0.65 10.2 3.8 0.32 11.3 0.7 1.8 2 0 0 2 2 2 0 AAA domain Cupin_8 PF13621.1 EMD69572.1 - 5.2e-39 134.2 0.0 9.5e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EMD69572.1 - 1.4e-23 83.3 0.0 2.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EMD69572.1 - 8e-18 63.9 7.7 2e-06 27.4 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EMD69572.1 - 1.8e-14 53.4 10.1 6.6e-07 29.3 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMD69572.1 - 3.5e-09 36.4 0.1 0.3 11.0 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Cupin_4 PF08007.7 EMD69572.1 - 5.5e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein WD40 PF00400.27 EMD69573.1 - 6.4e-07 29.0 0.1 4.4e-05 23.1 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMD69573.1 - 0.00042 19.7 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 EMD69573.1 - 0.0022 17.1 0.0 0.09 11.8 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region DNA_gyraseA_C PF03989.8 EMD69573.1 - 0.019 14.2 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Hira PF07569.6 EMD69573.1 - 0.096 11.8 0.0 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 TUP1-like enhancer of split PI31_Prot_N PF11566.3 EMD69574.1 - 1.1e-29 103.0 0.0 1.3e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EMD69574.1 - 7.5e-15 55.3 17.9 7.5e-15 55.3 12.4 3.4 3 1 1 4 4 4 1 PI31 proteasome regulator zf-C2H2 PF00096.21 EMD69575.1 - 3.9e-10 39.4 12.2 0.0089 16.3 0.7 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69575.1 - 5e-09 35.8 11.4 0.027 14.8 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD69575.1 - 2.1e-06 27.7 10.1 0.022 15.0 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMD69575.1 - 0.044 13.6 2.1 2.3 8.2 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD69575.1 - 0.5 10.5 3.7 5 7.4 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ion_trans PF00520.26 EMD69576.1 - 3.5e-07 29.6 12.3 8e-07 28.4 8.6 1.8 1 1 0 1 1 1 1 Ion transport protein Asn_synthase PF00733.16 EMD69577.1 - 1.9e-51 175.0 0.0 2.6e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMD69577.1 - 2.9e-05 23.7 0.0 0.00016 21.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMD69577.1 - 0.004 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMD69577.1 - 0.034 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein VPS9 PF02204.13 EMD69578.1 - 1.9e-28 98.5 0.0 3.4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EMD69578.1 - 4.5e-10 38.8 0.1 8e-09 34.8 0.0 2.3 2 0 0 2 2 2 1 CUE domain zf-C2H2 PF00096.21 EMD69579.1 - 3.1e-12 46.0 76.3 0.16 12.4 0.1 11.9 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD69579.1 - 9.7e-10 38.0 61.9 0.046 14.0 0.1 11.0 11 0 0 11 11 11 8 C2H2-type zinc finger zf-met PF12874.2 EMD69579.1 - 3.1e-08 33.5 40.5 0.017 15.3 0.1 9.9 10 0 0 10 10 10 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMD69579.1 - 6.3e-07 29.3 39.8 0.00011 22.1 0.3 8.9 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMD69579.1 - 0.27 11.3 45.0 1 9.5 2.6 6.6 2 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) Aldedh PF00171.17 EMD69581.1 - 1.2e-153 511.7 0.3 1.5e-153 511.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMD69581.1 - 1.4e-05 24.0 0.0 2.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMD69581.1 - 0.0097 15.1 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ank_2 PF12796.2 EMD69582.1 - 1.2e-15 57.5 0.0 3.8e-10 39.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD69582.1 - 3.7e-12 45.3 0.2 0.0013 18.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMD69582.1 - 3e-09 37.1 0.0 0.0021 18.4 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD69582.1 - 5.6e-09 35.9 0.0 3.1e-06 27.2 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69582.1 - 1.8e-08 33.8 0.1 0.0003 20.7 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat eRF1_3 PF03465.10 EMD69582.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 eRF1 domain 3 Glyco_hydro_67M PF07488.7 EMD69583.1 - 3.9e-145 482.8 0.1 6.2e-145 482.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EMD69583.1 - 5e-95 317.2 1.8 9.5e-95 316.2 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EMD69583.1 - 7e-28 97.1 0.1 1.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EMD69583.1 - 0.0003 21.3 0.2 0.00085 19.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_S9 PF00326.16 EMD69584.1 - 5.1e-48 163.1 0.5 9.3e-48 162.2 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD69584.1 - 1.3e-08 34.7 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 EMD69584.1 - 0.043 12.8 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PTR2 PF00854.16 EMD69585.1 - 6.6e-43 146.9 13.5 2.8e-42 144.8 9.4 1.9 1 1 0 1 1 1 1 POT family FixQ PF05545.6 EMD69585.1 - 0.057 13.0 1.6 4.2 7.0 0.2 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Bac_rhodopsin PF01036.13 EMD69585.1 - 1.1 8.5 9.7 0.33 10.2 0.3 3.0 3 0 0 3 3 3 0 Bacteriorhodopsin-like protein F-box PF00646.28 EMD69586.1 - 0.00033 20.2 0.1 0.00092 18.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 EMD69588.1 - 8.7e-10 38.3 9.9 1.7e-09 37.4 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD69588.1 - 3.9e-06 25.9 0.0 7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 EMD69590.1 - 0.041 13.5 0.1 0.041 13.5 0.1 2.3 3 0 0 3 3 3 0 F-box domain IPK PF03770.11 EMD69591.1 - 6.2e-60 202.2 0.0 7.3e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 EMD69592.1 - 1.7e-114 382.7 0.0 2.3e-114 382.3 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.12 EMD69592.1 - 4.1e-12 45.7 0.0 9.2e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 La domain RTA1 PF04479.8 EMD69593.1 - 2.8e-31 108.7 1.4 5.1e-31 107.9 1.0 1.4 1 0 0 1 1 1 1 RTA1 like protein PMP1_2 PF08114.6 EMD69593.1 - 0.034 13.6 0.2 0.12 11.8 0.1 1.9 1 0 0 1 1 1 0 ATPase proteolipid family NADH-u_ox-rdase PF10785.4 EMD69593.1 - 0.19 12.0 1.9 2.1 8.6 0.5 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit UPF0086 PF01868.11 EMD69594.1 - 1.4e-11 43.8 0.1 2.8e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L6 PF00347.18 EMD69595.1 - 1.3e-24 86.4 5.4 2.7e-13 50.2 1.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Aldo_ket_red PF00248.16 EMD69596.1 - 1e-65 221.3 0.0 1.3e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_60s PF00428.14 EMD69597.1 - 0.029 14.7 0.1 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like_2 PF13013.1 EMD69598.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Clp1 PF06807.9 EMD69599.1 - 3.9e-22 78.9 0.0 6.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EMD69599.1 - 1.6e-08 34.3 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EMD69599.1 - 4.6e-06 26.3 0.0 9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EMD69599.1 - 0.00036 20.4 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMD69599.1 - 0.0032 16.6 0.1 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EMD69599.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EMD69599.1 - 0.035 13.8 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EMD69599.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EMD69599.1 - 0.047 14.1 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EMD69599.1 - 0.054 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.1 EMD69599.1 - 0.07 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EMD69599.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EMD69599.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1237 PF06824.6 EMD69600.1 - 1.9e-180 600.0 0.0 2.2e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Abhydrolase_6 PF12697.2 EMD69601.1 - 5.7e-19 68.9 2.7 1.9e-18 67.1 0.6 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD69601.1 - 4.3e-08 33.0 0.0 7.6e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD69601.1 - 7.2e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMD69601.1 - 0.15 11.2 0.0 0.97 8.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family V_ATPase_I PF01496.14 EMD69601.1 - 4.6 4.9 3.7 6.9 4.3 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EMD69601.1 - 9.4 5.1 9.4 19 4.1 6.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 ORC6 PF05460.8 EMD69603.1 - 0.9 8.5 15.4 1.5 7.8 0.3 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RhoGEF PF00621.15 EMD69604.1 - 9.2e-26 90.8 0.0 3e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EMD69604.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF342 PF03961.8 EMD69604.1 - 3.3 6.0 6.6 1.1 7.5 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2036 PF09724.4 EMD69605.1 - 8.4e-23 81.0 0.0 1.1e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Hemerythrin PF01814.18 EMD69606.1 - 4.2e-13 49.5 2.7 5.7e-13 49.1 1.9 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ribosomal_L30_N PF08079.7 EMD69606.1 - 2 8.4 4.0 0.84 9.6 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain DUF3112 PF11309.3 EMD69607.1 - 2.5e-37 128.1 17.1 1.7e-35 122.1 2.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Tyrosinase PF00264.15 EMD69610.1 - 1.7e-44 152.6 0.2 2.3e-44 152.2 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1100 PF06500.6 EMD69610.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF4202 PF13875.1 EMD69611.1 - 9.8e-83 276.3 0.1 1.1e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) RepB-RCR_reg PF10723.4 EMD69611.1 - 0.0036 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Replication regulatory protein RepB Fungal_trans PF04082.13 EMD69612.1 - 3.9e-20 71.8 3.1 6.4e-20 71.1 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69612.1 - 5.8e-08 32.5 9.9 9.2e-08 31.8 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMD69613.1 - 4.3e-20 71.6 0.0 7.2e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69613.1 - 2.5e-07 30.4 14.2 4e-07 29.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A2M PF00207.17 EMD69614.1 - 0.077 12.5 0.0 0.95 9.0 0.0 2.3 1 1 1 2 2 2 0 Alpha-2-macroglobulin family Sulfate_transp PF00916.15 EMD69616.1 - 7.3e-66 222.0 6.3 1.1e-65 221.3 4.4 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMD69616.1 - 2.2e-28 97.7 3.3 2.2e-28 97.7 2.3 3.2 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMD69616.1 - 3.2e-07 29.7 0.0 6.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_1 PF07690.11 EMD69619.1 - 1.1e-25 90.1 42.3 2.3e-25 89.0 29.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD69619.1 - 3.8e-25 88.1 28.8 4.9e-25 87.7 20.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMD69619.1 - 0.00057 18.3 5.8 0.00057 18.3 4.0 3.3 1 1 0 2 2 2 1 MFS/sugar transport protein Myco_19_kDa PF05481.7 EMD69619.1 - 0.0077 16.0 1.2 0.027 14.3 0.9 1.9 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen adh_short PF00106.20 EMD69621.1 - 1.8e-35 122.3 0.0 2.7e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69621.1 - 1.6e-14 54.2 0.0 2.2e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69621.1 - 9.4e-13 48.2 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMD69621.1 - 0.0032 16.3 0.0 0.013 14.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMD69621.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lin0512_fam PF09585.5 EMD69621.1 - 0.024 14.1 0.1 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Epimerase PF01370.16 EMD69621.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMD69621.1 - 0.047 12.7 0.1 1.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EMD69621.1 - 0.059 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Filo_glycop PF01611.11 EMD69622.1 - 0.59 8.8 2.5 0.62 8.7 1.7 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein TP53IP5 PF15331.1 EMD69622.1 - 8.8 6.1 8.1 9.7 6.0 5.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Peptidase_S10 PF00450.17 EMD69623.1 - 5.4e-96 322.2 0.0 6.8e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMD69623.1 - 0.0069 16.2 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family CBFD_NFYB_HMF PF00808.18 EMD69624.1 - 2.8e-12 46.5 0.4 5.1e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMD69624.1 - 0.0012 18.8 0.5 0.0022 18.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4653 PF15546.1 EMD69624.1 - 0.06 12.6 2.1 0.078 12.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF2796 PF10986.3 EMD69624.1 - 0.15 12.0 0.7 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF4124 PF13511.1 EMD69624.1 - 1.2 9.1 4.7 1.9 8.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Macro PF01661.16 EMD69625.1 - 6e-18 64.8 0.0 9.2e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Macro domain UCR_TM PF02921.9 EMD69626.1 - 6.8e-20 71.0 0.3 1.3e-19 70.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EMD69626.1 - 1.4e-17 63.0 0.0 2.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain BCIP PF13862.1 EMD69627.1 - 5.7e-71 238.0 0.0 7.2e-71 237.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GATase PF00117.23 EMD69628.1 - 3.6e-40 137.4 0.0 5.8e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EMD69628.1 - 1.3e-38 130.5 0.0 3.9e-38 129.0 0.0 1.8 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EMD69628.1 - 3e-12 45.9 0.2 6.8e-07 28.4 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EMD69628.1 - 2.1e-08 33.8 0.0 3.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EMD69628.1 - 6.1e-05 22.4 0.0 0.0012 18.2 0.0 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EMD69628.1 - 0.0003 20.3 0.0 0.0088 15.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EMD69628.1 - 0.0016 17.1 0.2 0.0077 14.8 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.14 EMD69628.1 - 0.014 14.4 0.1 0.052 12.5 0.1 1.8 2 0 0 2 2 2 0 Arginosuccinate synthase Asn_synthase PF00733.16 EMD69628.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EMD69628.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Voltage_CLC PF00654.15 EMD69629.1 - 2.4e-88 296.5 25.2 2.4e-88 296.5 17.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMD69629.1 - 5.3e-13 48.5 0.1 2.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain IRK PF01007.15 EMD69629.1 - 0.65 8.7 2.9 0.96 8.1 1.6 1.5 1 1 1 2 2 2 0 Inward rectifier potassium channel DHC_N1 PF08385.7 EMD69630.1 - 3e-190 633.4 4.2 3e-190 633.4 2.9 4.7 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EMD69630.1 - 4.2e-129 430.6 7.4 4.2e-129 430.6 5.2 5.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EMD69630.1 - 1.9e-106 356.8 0.0 1.9e-106 356.8 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EMD69630.1 - 2.8e-79 265.9 0.0 1e-78 264.0 0.0 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EMD69630.1 - 6.9e-44 149.3 0.3 3.2e-43 147.1 0.0 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EMD69630.1 - 2.5e-42 144.7 0.1 3.2e-41 141.1 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EMD69630.1 - 5e-41 140.5 9.5 5e-41 140.5 6.6 2.9 4 0 0 4 4 4 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMD69630.1 - 2.1e-31 108.5 0.0 1.3e-11 44.3 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EMD69630.1 - 8.5e-21 74.2 0.0 6.8e-20 71.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EMD69630.1 - 1.4e-14 54.3 2.8 0.019 15.0 0.0 7.1 8 0 0 8 8 4 3 AAA domain AAA PF00004.24 EMD69630.1 - 2e-12 47.4 0.0 0.0026 17.9 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMD69630.1 - 4.7e-11 42.7 0.1 0.066 13.0 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EMD69630.1 - 9.5e-08 32.8 0.0 0.072 13.9 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EMD69630.1 - 5.9e-07 29.4 0.7 0.17 11.8 0.0 6.3 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.1 EMD69630.1 - 6.8e-07 29.6 4.2 0.09 13.0 0.0 5.5 5 0 0 5 5 4 2 AAA domain T2SE PF00437.15 EMD69630.1 - 1.2e-06 27.6 0.0 0.065 12.1 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 EMD69630.1 - 6.5e-06 25.5 0.1 0.93 9.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 EMD69630.1 - 1.7e-05 25.1 0.6 4.9 7.4 0.0 5.7 4 0 0 4 4 4 1 ABC transporter AAA_19 PF13245.1 EMD69630.1 - 2.6e-05 23.9 0.3 0.83 9.4 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EMD69630.1 - 7.5e-05 22.3 5.1 0.19 11.1 0.1 5.2 6 0 0 6 6 5 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EMD69630.1 - 7.6e-05 21.9 1.4 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EMD69630.1 - 9.1e-05 22.5 20.2 0.21 11.5 0.0 8.8 8 2 1 9 9 9 2 AAA ATPase domain AAA_25 PF13481.1 EMD69630.1 - 0.0072 15.7 1.1 0.32 10.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EMD69630.1 - 0.016 15.3 0.1 35 4.6 0.0 4.4 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EMD69630.1 - 0.045 13.4 0.6 22 4.7 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Troponin PF00992.15 EMD69631.1 - 1 9.4 8.7 4.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Troponin Fringe PF02434.11 EMD69632.1 - 0.00033 19.9 0.0 0.0025 17.0 0.0 2.1 2 0 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EMD69632.1 - 0.0017 18.0 2.6 0.004 16.8 1.8 1.6 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 EMD69632.1 - 0.016 14.8 0.0 0.067 12.7 0.0 1.9 1 1 1 2 2 2 0 Galactosyltransferase NYN PF01936.13 EMD69635.1 - 8.2e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 NYN domain Apc4 PF12896.2 EMD69635.1 - 0.05 12.9 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 TPR_12 PF13424.1 EMD69636.1 - 4.8e-91 298.7 21.4 2.2e-17 62.7 0.0 6.0 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 EMD69636.1 - 1.3e-90 295.0 23.7 3.5e-13 48.9 0.0 9.5 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69636.1 - 2.7e-27 92.3 16.1 0.0039 16.8 0.0 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat HET PF06985.6 EMD69636.1 - 8.7e-21 74.5 11.0 2.4e-18 66.6 7.4 3.7 2 1 0 2 2 1 1 Heterokaryon incompatibility protein (HET) TPR_4 PF07721.9 EMD69636.1 - 4.3e-19 66.9 1.0 0.12 12.9 0.0 9.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69636.1 - 2.6e-18 64.7 7.0 0.13 11.8 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMD69636.1 - 3.6e-18 64.1 11.9 0.062 13.5 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69636.1 - 4.4e-17 60.5 10.9 0.071 13.0 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69636.1 - 4.7e-14 51.7 8.2 7.6e-05 22.2 0.1 5.6 2 1 4 6 6 6 5 TPR repeat NB-ARC PF00931.17 EMD69636.1 - 9.6e-14 50.8 0.0 5.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_19 PF14559.1 EMD69636.1 - 1.3e-12 47.8 5.9 0.061 13.6 0.0 8.2 1 1 7 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69636.1 - 2.8e-10 39.2 6.0 4.1 7.4 0.0 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69636.1 - 1.4e-09 38.3 14.8 0.076 13.7 0.0 7.6 2 1 6 8 8 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EMD69636.1 - 2e-08 34.2 9.9 0.24 11.5 0.0 7.2 2 1 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 EMD69636.1 - 1e-07 32.1 0.4 1e-07 32.1 0.3 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD69636.1 - 1.6e-07 31.5 0.0 6.5e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 EMD69636.1 - 7e-06 26.2 21.5 2.5 8.9 0.0 9.3 9 1 0 9 9 7 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EMD69636.1 - 5.2e-05 23.0 0.0 0.00018 21.3 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase PPR PF01535.15 EMD69636.1 - 0.00012 21.8 2.8 21 5.3 0.0 7.0 7 0 0 7 7 7 0 PPR repeat TPR_20 PF14561.1 EMD69636.1 - 0.00033 20.7 9.9 4.9 7.3 0.0 6.6 1 1 5 7 7 7 1 Tetratricopeptide repeat IstB_IS21 PF01695.12 EMD69636.1 - 0.00083 18.8 0.0 0.0024 17.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_6 PF13174.1 EMD69636.1 - 0.0026 18.1 15.5 17 6.1 0.1 8.0 7 1 0 7 7 7 0 Tetratricopeptide repeat AAA PF00004.24 EMD69636.1 - 0.0033 17.6 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PPR_3 PF13812.1 EMD69636.1 - 0.0055 16.8 2.0 99 3.6 0.0 6.0 6 0 0 6 6 5 0 Pentatricopeptide repeat domain DNAJ_related PF12339.3 EMD69636.1 - 0.012 15.5 5.0 0.82 9.5 0.7 3.6 2 1 1 3 3 3 0 DNA-J related protein TPR_3 PF07720.7 EMD69636.1 - 0.021 14.6 0.1 5.4 6.9 0.0 4.7 7 0 0 7 7 5 0 Tetratricopeptide repeat AAA_5 PF07728.9 EMD69636.1 - 0.021 14.5 0.1 0.071 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMD69636.1 - 0.022 14.1 0.0 0.086 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain zf-Mss51 PF13824.1 EMD69636.1 - 0.055 13.3 7.1 11 6.0 0.1 5.3 6 0 0 6 6 5 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA_17 PF13207.1 EMD69636.1 - 0.11 13.2 0.0 0.7 10.7 0.0 2.5 2 0 0 2 2 1 0 AAA domain DUF3382 PF11862.3 EMD69637.1 - 0.014 15.3 0.6 0.54 10.2 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) TraX PF05857.6 EMD69637.1 - 0.14 11.7 4.5 0.12 12.0 1.8 1.7 1 1 0 2 2 2 0 TraX protein VWA_2 PF13519.1 EMD69638.1 - 2.9e-07 30.7 0.1 2.5e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain YjeF_N PF03853.10 EMD69638.1 - 0.0089 15.6 0.0 0.064 12.8 0.0 2.4 3 0 0 3 3 3 1 YjeF-related protein N-terminus VWA PF00092.23 EMD69638.1 - 0.018 14.7 0.1 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain SWIM PF04434.12 EMD69638.1 - 0.05 13.0 0.4 0.13 11.7 0.3 1.8 1 0 0 1 1 1 0 SWIM zinc finger zf-C2HC_2 PF13913.1 EMD69638.1 - 0.062 12.9 2.1 0.12 12.0 0.9 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Lipase_3 PF01764.20 EMD69639.1 - 1.4e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMD69639.1 - 0.0014 18.4 0.1 0.0032 17.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMD69639.1 - 0.011 14.9 0.2 0.053 12.8 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family AIRS PF00586.19 EMD69639.1 - 0.014 15.6 0.2 0.034 14.3 0.1 1.7 1 1 1 2 2 2 0 AIR synthase related protein, N-terminal domain Abhydrolase_2 PF02230.11 EMD69639.1 - 0.056 12.8 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EMD69639.1 - 0.056 12.9 0.3 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMD69639.1 - 0.056 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BTB PF00651.26 EMD69640.1 - 2.1e-07 30.8 0.2 4.7e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Lipase_GDSL_2 PF13472.1 EMD69641.1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF972 PF06156.8 EMD69642.1 - 0.034 14.5 1.6 0.034 14.5 1.1 5.8 3 1 2 5 5 5 0 Protein of unknown function (DUF972) Bcr-Abl_Oligo PF09036.5 EMD69642.1 - 0.12 12.4 7.7 0.36 10.8 0.2 3.8 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF1192 PF06698.6 EMD69642.1 - 0.14 11.9 5.0 3.1 7.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Filament PF00038.16 EMD69642.1 - 0.25 10.7 40.8 0.26 10.7 7.0 3.4 2 1 1 3 3 3 0 Intermediate filament protein Nbl1_Borealin_N PF10444.4 EMD69642.1 - 4.1 6.8 7.4 12 5.3 0.1 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF334 PF03904.8 EMD69642.1 - 6.4 6.0 12.2 4.8 6.4 4.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF334) Sugar_tr PF00083.19 EMD69643.1 - 4e-74 249.8 24.4 4.6e-74 249.6 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69643.1 - 4.1e-31 107.9 23.6 1.2e-29 103.1 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD69643.1 - 3.8e-07 28.8 3.0 3.8e-07 28.8 2.1 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 EMD69643.1 - 5.5e-05 21.5 2.9 9e-05 20.8 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMD69643.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 4.2 4 0 0 4 4 4 1 MFS_1 like family MARVEL PF01284.18 EMD69644.1 - 1.6e-21 76.6 24.1 1.8e-21 76.4 16.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2306 PF10067.4 EMD69644.1 - 7.4 6.7 17.4 0.54 10.4 6.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF1422 PF07226.6 EMD69644.1 - 7.7 6.2 8.0 0.88 9.3 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Antimicrobial_1 PF08018.6 EMD69645.1 - 0.0094 15.8 0.9 0.015 15.1 0.6 1.4 1 0 0 1 1 1 1 Frog antimicrobial peptide SapB_2 PF03489.12 EMD69645.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Saposin-like type B, region 2 DPPIV_N PF00930.16 EMD69646.1 - 3e-102 341.8 2.5 4.4e-102 341.2 1.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMD69646.1 - 2.1e-37 128.4 0.2 3.7e-37 127.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD69646.1 - 1.7e-06 27.8 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMD69646.1 - 0.00027 20.4 1.0 0.00079 18.9 0.7 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EMD69646.1 - 0.00043 20.2 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EMD69646.1 - 0.011 15.4 3.6 0.16 11.6 0.1 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LSM PF01423.17 EMD69647.1 - 1.4e-16 59.7 0.0 1.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMD69647.1 - 0.0087 15.9 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2689 PF10894.3 EMD69647.1 - 0.05 13.3 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) PITH PF06201.8 EMD69648.1 - 2.6e-46 157.1 0.0 3.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EMD69648.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Snf7 PF03357.16 EMD69649.1 - 2.2e-33 115.0 14.8 2.2e-33 115.0 10.2 1.4 2 0 0 2 2 2 1 Snf7 CbiA PF01656.18 EMD69649.1 - 0.039 13.3 0.9 0.077 12.3 0.6 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Silic_transp PF03842.8 EMD69649.1 - 0.05 11.6 1.0 0.071 11.1 0.7 1.2 1 0 0 1 1 1 0 Silicon transporter Ead_Ea22 PF13935.1 EMD69649.1 - 1.7 8.9 12.8 0.16 12.2 2.6 2.1 2 0 0 2 2 2 0 Ead/Ea22-like protein PMSR PF01625.16 EMD69649.1 - 2.5 7.9 5.4 2.5 7.9 0.5 2.6 2 1 1 3 3 3 0 Peptide methionine sulfoxide reductase AAA PF00004.24 EMD69650.1 - 1.6e-88 293.6 0.0 2.1e-44 150.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMD69650.1 - 2.5e-11 43.1 0.0 0.00023 20.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMD69650.1 - 2.9e-11 43.6 5.8 0.00072 19.5 0.0 4.9 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EMD69650.1 - 6.1e-11 42.5 1.8 0.0082 16.2 0.0 5.6 3 2 2 5 5 4 2 AAA domain AAA_5 PF07728.9 EMD69650.1 - 1.4e-10 41.0 0.1 0.0011 18.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMD69650.1 - 4.1e-10 40.5 0.0 0.0001 23.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EMD69650.1 - 6.3e-09 35.8 0.0 0.0036 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EMD69650.1 - 1e-08 35.2 0.0 0.0018 18.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EMD69650.1 - 1.1e-08 35.0 0.0 0.0022 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMD69650.1 - 2e-08 33.3 0.1 0.00076 18.2 0.0 2.5 2 1 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EMD69650.1 - 4.1e-08 32.5 0.1 0.0026 16.8 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 EMD69650.1 - 8.8e-08 31.7 0.1 0.035 13.8 0.0 3.6 4 0 0 4 4 3 2 Part of AAA domain AAA_28 PF13521.1 EMD69650.1 - 1.3e-07 31.7 0.0 0.01 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMD69650.1 - 8.2e-07 29.1 0.0 0.063 13.4 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_3 PF07726.6 EMD69650.1 - 8.9e-07 28.5 0.0 0.0056 16.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMD69650.1 - 2.5e-06 27.0 0.2 0.02 14.3 0.1 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EMD69650.1 - 3.7e-06 27.2 3.6 0.01 16.1 0.0 3.8 5 0 0 5 5 2 2 AAA domain Mg_chelatase PF01078.16 EMD69650.1 - 5.3e-06 25.7 0.2 0.041 13.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EMD69650.1 - 3e-05 23.7 0.6 0.8 9.3 0.0 4.0 3 1 1 4 4 4 2 NACHT domain KaiC PF06745.8 EMD69650.1 - 5.7e-05 22.3 0.1 0.3 10.1 0.0 2.8 2 1 1 3 3 3 2 KaiC SKI PF01202.17 EMD69650.1 - 0.0001 22.2 0.7 0.19 11.5 0.0 3.3 4 0 0 4 4 2 2 Shikimate kinase ABC_tran PF00005.22 EMD69650.1 - 0.00012 22.3 0.0 0.11 12.7 0.0 3.1 3 0 0 3 3 2 1 ABC transporter Rad17 PF03215.10 EMD69650.1 - 0.00032 19.5 0.0 0.11 11.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EMD69650.1 - 0.00034 20.1 0.0 0.17 11.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EMD69650.1 - 0.00046 19.6 3.4 1 8.7 0.3 4.0 3 2 1 4 4 3 2 AAA domain DUF815 PF05673.8 EMD69650.1 - 0.00052 19.0 0.0 0.081 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EMD69650.1 - 0.00054 20.0 0.0 0.59 10.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 EMD69650.1 - 0.00063 19.0 0.1 0.37 9.9 0.1 2.9 4 0 0 4 4 3 1 PhoH-like protein AAA_11 PF13086.1 EMD69650.1 - 0.00077 19.1 0.5 3.6 7.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EMD69650.1 - 0.00084 18.9 0.1 0.65 9.6 0.0 2.7 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 EMD69650.1 - 0.0011 18.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family ResIII PF04851.10 EMD69650.1 - 0.0014 18.4 0.0 2.6 7.8 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EMD69650.1 - 0.0015 18.2 0.0 5.2 6.6 0.0 3.5 2 2 1 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 EMD69650.1 - 0.0021 16.9 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATP-synt_ab PF00006.20 EMD69650.1 - 0.0021 17.5 0.0 0.68 9.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EMD69650.1 - 0.003 17.1 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EMD69650.1 - 0.011 15.4 0.2 1.8 8.2 0.0 3.0 2 1 1 3 3 3 0 NTPase CPT PF07931.7 EMD69650.1 - 0.044 13.4 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.11 EMD69650.1 - 0.078 11.7 0.2 8.9 5.0 0.1 2.7 2 1 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.1 EMD69650.1 - 0.15 11.6 3.4 1.3 8.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.12 EMD69650.1 - 0.17 10.7 0.1 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ADH_zinc_N_2 PF13602.1 EMD69653.1 - 5.8e-13 49.8 0.0 1.2e-12 48.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD69653.1 - 1.1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD69653.1 - 3.8e-06 26.4 0.0 7.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PAP2 PF01569.16 EMD69654.1 - 3.5e-25 88.1 0.0 6e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily CUE PF02845.11 EMD69655.1 - 8.9e-12 44.2 0.0 1.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Herpes_BLLF1 PF05109.8 EMD69655.1 - 0.5 8.2 4.7 0.81 7.5 3.3 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Podoplanin PF05808.6 EMD69656.1 - 0.34 10.4 3.7 0.12 11.9 0.3 1.8 2 0 0 2 2 2 0 Podoplanin Pyr_redox_3 PF13738.1 EMD69657.1 - 1.5e-22 80.7 0.0 1.2e-21 77.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMD69657.1 - 4.8e-12 44.8 0.1 4.5e-11 41.6 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMD69657.1 - 1.1e-09 38.4 0.0 2.5e-05 24.2 0.0 3.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMD69657.1 - 1.4e-09 37.3 0.0 1.5e-07 30.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMD69657.1 - 0.0012 18.8 0.0 0.0091 15.9 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMD69657.1 - 0.0014 17.8 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMD69657.1 - 0.0062 16.2 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMD69657.1 - 0.0075 16.6 0.1 0.58 10.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMD69657.1 - 0.046 12.7 0.0 0.97 8.4 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain adh_short PF00106.20 EMD69658.1 - 6.3e-17 61.9 0.1 2.6e-16 59.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69658.1 - 7e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMD69658.1 - 0.069 12.9 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF385 PF04075.9 EMD69659.1 - 0.036 14.0 0.5 24 4.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF385) Sulfate_transp PF00916.15 EMD69660.1 - 3.8e-53 180.2 8.6 7.3e-53 179.3 5.9 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMD69660.1 - 3.5e-29 100.2 0.9 3.5e-29 100.2 0.6 3.6 3 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMD69660.1 - 9.6e-13 47.5 0.0 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMD69660.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.1 EMD69660.1 - 0.013 14.8 0.4 0.033 13.5 0.3 1.7 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Lipase_chap PF03280.9 EMD69662.1 - 0.012 15.1 0.3 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein EMP24_GP25L PF01105.19 EMD69663.1 - 1.3e-45 155.3 0.3 1.5e-45 155.1 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 EMD69664.1 - 0.0042 17.1 1.2 0.017 15.2 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMD69664.1 - 0.043 13.8 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.3 EMD69664.1 - 0.17 11.7 5.3 0.95 9.3 0.2 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Alpha-amylase PF00128.19 EMD69665.1 - 4e-98 328.6 1.7 6.6e-98 327.9 1.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMD69665.1 - 3.5e-05 22.8 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Imm15 PF15590.1 EMD69665.1 - 0.0027 16.7 0.1 0.0074 15.3 0.1 1.7 1 0 0 1 1 1 1 Immunity protein 15 Alpha-amylase_C PF02806.13 EMD69665.1 - 0.019 15.0 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain AA_permease PF00324.16 EMD69666.1 - 0.0028 16.0 0.3 0.0051 15.2 0.2 1.4 1 0 0 1 1 1 1 Amino acid permease NfeD PF01957.13 EMD69666.1 - 0.035 14.2 1.0 3.8 7.6 0.6 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding FAD_binding_4 PF01565.18 EMD69668.1 - 5.7e-24 84.1 2.2 9.4e-24 83.4 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EMD69669.1 - 1.2e-45 154.8 0.0 1.9e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMD69669.1 - 4.8e-30 103.7 0.0 5.6e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EMD69669.1 - 0.0031 17.9 0.0 0.0088 16.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EMD69669.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EMD69669.1 - 0.034 14.2 0.0 0.098 12.7 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EMD69669.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EMD69670.1 - 2.6e-50 171.3 0.6 3.1e-50 171.0 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD69670.1 - 1.1e-06 27.8 0.0 0.0026 16.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMD69670.1 - 0.00017 21.7 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD69670.1 - 0.00055 19.9 0.1 0.00055 19.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD69670.1 - 0.0041 16.9 0.3 0.014 15.2 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMD69670.1 - 0.0048 15.8 0.0 0.073 11.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMD69670.1 - 0.025 13.6 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EMD69670.1 - 0.025 14.4 3.9 0.031 14.1 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMD69670.1 - 0.035 12.5 0.2 3 6.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 EMD69671.1 - 6.2e-26 90.9 46.7 5.5e-24 84.5 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69671.1 - 1e-22 80.3 18.8 1.1e-22 80.2 11.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter GMC_oxred_N PF00732.14 EMD69672.1 - 5.7e-54 183.2 0.0 8.1e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD69672.1 - 4.9e-36 124.1 0.3 9.2e-36 123.2 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD69672.1 - 3.6e-06 26.1 0.0 0.00023 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD69672.1 - 2.2e-05 24.5 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMD69672.1 - 0.0013 17.6 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMD69672.1 - 0.037 12.8 0.1 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EMD69672.1 - 0.046 12.5 0.2 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A EmrE PF13536.1 EMD69673.1 - 0.018 15.2 2.4 0.018 15.2 1.7 1.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter PhyH PF05721.8 EMD69675.1 - 7e-14 52.3 0.0 9.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.19 EMD69676.1 - 1.3e-11 44.3 0.0 3.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin DUF1510 PF07423.6 EMD69676.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Thioredoxin_7 PF13899.1 EMD69676.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like ARGLU PF15346.1 EMD69677.1 - 0.072 12.8 22.7 0.1 12.3 15.8 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 TTKRSYEDQ PF10212.4 EMD69677.1 - 0.097 11.5 3.9 0.11 11.4 2.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein HAUS6_N PF14661.1 EMD69677.1 - 0.39 10.0 6.8 0.47 9.7 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spore_coat_CotO PF14153.1 EMD69677.1 - 0.85 9.0 9.2 1.1 8.6 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_3_Rpc31 PF11705.3 EMD69677.1 - 1.2 9.0 6.8 2 8.2 4.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Podoplanin PF05808.6 EMD69678.1 - 0.22 11.0 0.1 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Podoplanin DUF2668 PF10873.3 EMD69678.1 - 2.7 8.1 10.9 0.23 11.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Adeno_E3_CR2 PF02439.10 EMD69678.1 - 4.9 6.7 6.4 13 5.4 4.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ThiF PF00899.16 EMD69679.1 - 4.1e-51 172.3 0.0 4.9e-33 113.8 0.0 2.6 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EMD69679.1 - 3.3e-41 140.3 0.0 8.1e-41 139.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EMD69679.1 - 1.4e-36 123.9 4.0 2e-26 91.3 0.3 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMD69679.1 - 3.3e-24 83.9 1.9 6.8e-21 73.3 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site ParA PF10609.4 EMD69680.1 - 8.6e-35 118.4 0.0 1.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMD69680.1 - 3.7e-13 49.3 0.0 5.8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMD69680.1 - 2e-05 24.5 0.0 7.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EMD69680.1 - 0.00035 19.6 1.1 0.0012 17.9 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 EMD69680.1 - 0.0016 18.0 0.0 0.059 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EMD69680.1 - 0.0069 15.4 0.0 0.015 14.3 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 EMD69680.1 - 0.012 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 EMD69680.1 - 0.15 11.1 0.0 1.8 7.6 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.10 EMD69680.1 - 0.2 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PhoD PF09423.5 EMD69681.1 - 4.6e-08 32.0 0.1 6.6e-06 24.9 0.2 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase FAD_binding_4 PF01565.18 EMD69684.1 - 2.8e-17 62.4 0.8 5.4e-17 61.5 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMD69684.1 - 1.9e-11 43.6 0.1 4.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FMN_dh PF01070.13 EMD69685.1 - 1.6e-108 362.7 0.0 2e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMD69685.1 - 4.9e-21 74.3 0.0 8.4e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMD69685.1 - 2.9e-05 23.1 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EMD69685.1 - 0.00063 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EMD69685.1 - 0.00094 18.3 0.0 0.021 13.8 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EMD69685.1 - 0.0049 15.8 0.1 0.014 14.2 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Methyltransf_11 PF08241.7 EMD69686.1 - 2.9e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMD69686.1 - 6.8e-06 25.3 0.0 0.00075 18.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMD69686.1 - 1.4e-05 24.7 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD69686.1 - 2.5e-05 24.0 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD69686.1 - 3.1e-05 24.3 0.0 5.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD69686.1 - 0.078 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 4HBT_3 PF13622.1 EMD69687.1 - 8.8e-31 107.5 0.2 1.2e-30 107.1 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMD69687.1 - 6.5e-05 22.5 1.2 0.26 10.8 0.0 3.9 3 1 0 3 3 3 3 Acyl-CoA thioesterase AA_permease_2 PF13520.1 EMD69688.1 - 3e-54 184.2 36.3 3.8e-54 183.8 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD69688.1 - 4.4e-26 91.2 22.7 4.4e-26 91.2 15.8 2.2 2 1 0 2 2 2 1 Amino acid permease XH PF03469.9 EMD69689.1 - 8.7e-05 22.1 13.9 0.041 13.5 0.1 4.6 1 1 2 4 4 4 2 XH domain PhoU_div PF01865.11 EMD69689.1 - 0.0011 18.1 7.0 0.074 12.2 0.3 3.2 3 1 1 4 4 4 2 Protein of unknown function DUF47 Apolipoprotein PF01442.13 EMD69689.1 - 0.0012 18.3 9.5 0.023 14.1 3.8 3.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ArsC PF03960.10 EMD69689.1 - 0.0033 17.4 4.9 6.6 6.8 0.1 4.2 3 2 1 4 4 4 1 ArsC family Peptidase_M41 PF01434.13 EMD69689.1 - 0.013 15.0 5.4 0.072 12.5 1.0 3.0 1 1 1 3 3 3 0 Peptidase family M41 PhoU PF01895.14 EMD69689.1 - 0.038 14.4 4.2 0.77 10.2 0.0 3.8 4 0 0 4 4 4 0 PhoU domain TipAS PF07739.8 EMD69689.1 - 0.039 14.2 14.3 2.6 8.3 0.0 5.1 2 1 3 5 5 5 0 TipAS antibiotic-recognition domain HisKA_3 PF07730.8 EMD69689.1 - 0.23 11.8 6.3 5.3 7.4 0.0 4.1 4 1 1 5 5 5 0 Histidine kinase CDC37_N PF03234.9 EMD69689.1 - 1.9 8.7 13.8 4.7 7.4 0.5 2.7 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding ATP-synt_B PF00430.13 EMD69689.1 - 3.1 7.6 17.5 0.24 11.1 4.5 3.6 3 1 0 4 4 4 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 EMD69689.1 - 4.1 7.8 0.0 4.1 7.8 0.0 5.8 3 2 4 7 7 6 0 Bacterial protein of unknown function (DUF883) Shadoo PF14999.1 EMD69689.1 - 8.2 6.2 10.9 16 5.3 7.6 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective FlgN PF05130.7 EMD69689.1 - 9.2 6.5 12.5 7.9 6.7 0.1 3.5 2 1 1 3 3 3 0 FlgN protein HAD_2 PF13419.1 EMD69690.1 - 7.9e-23 81.5 0.0 1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMD69690.1 - 1.7e-12 48.2 0.0 8.3e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMD69690.1 - 1e-08 34.7 0.0 2.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMD69690.1 - 0.00032 20.5 0.0 0.0027 17.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EMD69690.1 - 0.00047 20.3 0.0 0.0006 20.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EFP PF01132.15 EMD69690.1 - 0.024 14.3 0.2 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain NIF PF03031.13 EMD69690.1 - 0.06 13.0 0.0 1.8 8.1 0.0 2.2 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase LVIVD PF08309.6 EMD69691.1 - 0.00056 18.8 0.7 0.72 8.9 0.0 4.2 4 0 0 4 4 4 2 LVIVD repeat Peptidase_M28 PF04389.12 EMD69692.1 - 1.5e-27 96.4 0.0 2.6e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMD69692.1 - 1.1e-13 50.6 0.3 2.4e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMD69692.1 - 8.1e-05 22.2 0.3 0.00022 20.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 zf-RING_2 PF13639.1 EMD69694.1 - 0.0042 16.8 5.4 0.0042 16.8 3.8 4.1 3 1 1 4 4 4 2 Ring finger domain PHD PF00628.24 EMD69694.1 - 0.0049 16.5 7.2 0.0049 16.5 5.0 3.6 3 1 1 4 4 4 2 PHD-finger FAD_binding_3 PF01494.14 EMD69695.1 - 3.2e-11 42.8 2.6 3.4e-07 29.6 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EMD69695.1 - 5e-05 23.1 0.4 0.035 13.8 0.2 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding SE PF08491.5 EMD69695.1 - 0.00027 19.8 0.0 0.0021 16.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EMD69695.1 - 0.00031 20.7 0.7 0.00074 19.4 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMD69695.1 - 0.00032 19.7 1.5 0.002 17.0 1.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD69695.1 - 0.016 14.1 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMD69695.1 - 0.043 12.4 2.6 0.056 12.0 0.5 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EMD69695.1 - 0.094 11.5 0.2 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMD69695.1 - 0.11 10.9 0.8 0.16 10.3 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMD69695.1 - 0.16 12.3 0.9 0.36 11.2 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EMD69697.1 - 6e-23 81.1 30.4 1.3e-21 76.6 21.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.3 EMD69697.1 - 0.1 11.7 1.6 0.26 10.4 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) AA_permease_2 PF13520.1 EMD69698.1 - 3.3e-78 263.1 30.9 4.1e-78 262.8 21.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD69698.1 - 2.2e-20 72.4 25.9 3.5e-20 71.8 18.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pectinesterase PF01095.14 EMD69699.1 - 5.2e-28 97.4 0.0 4.1e-24 84.6 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase p450 PF00067.17 EMD69700.1 - 2.8e-64 217.3 0.0 3.5e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EMD69701.1 - 6.7e-37 126.5 2.3 1e-36 125.9 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EMD69701.1 - 0.66 10.0 10.4 1.8 8.5 7.2 1.7 1 0 0 1 1 1 0 Chitin recognition protein DSPc PF00782.15 EMD69702.1 - 1.2e-22 79.9 0.0 1.6e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain DSPn PF14671.1 EMD69702.1 - 0.026 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Peptidase_S28 PF05577.7 EMD69703.1 - 5e-53 180.2 1.5 7.4e-53 179.6 1.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 CorA PF01544.13 EMD69704.1 - 2.6e-05 23.4 16.9 0.0013 17.8 11.7 2.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PNP_UDP_1 PF01048.15 EMD69705.1 - 2.2e-11 43.2 2.1 6.7e-11 41.6 1.5 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 EMD69706.1 - 1.2e-16 60.7 0.7 6.1e-12 45.7 0.0 4.4 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMD69706.1 - 2.5e-10 39.6 1.3 0.1 12.4 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EMD69706.1 - 3.1e-10 40.3 0.8 0.0059 17.0 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 EMD69706.1 - 1.1e-06 28.3 0.7 4.8e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.1 EMD69706.1 - 5.1e-06 26.5 0.0 0.77 10.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69706.1 - 7.7e-06 25.6 5.0 3.8 8.0 0.0 6.5 7 0 0 7 7 6 1 Ankyrin repeat AAA_16 PF13191.1 EMD69706.1 - 2.7e-05 24.2 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD69706.1 - 8.6e-05 22.6 0.0 0.00069 19.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMD69706.1 - 0.084 11.8 4.1 0.066 12.1 0.2 2.1 1 1 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.1 EMD69706.1 - 0.12 11.9 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMD69706.1 - 0.18 12.0 0.7 0.77 10.0 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Fungal_trans PF04082.13 EMD69707.1 - 6.8e-12 44.8 1.3 7.5e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69707.1 - 1.3e-06 28.2 11.0 2.1e-06 27.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EMD69707.1 - 0.23 10.4 8.6 0.46 9.4 6.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CGI-121 PF08617.5 EMD69708.1 - 8.1e-53 178.3 0.1 9.5e-53 178.1 0.1 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 COX5B PF01215.14 EMD69709.1 - 1.3e-38 131.7 0.0 2.1e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Isochorismatase PF00857.15 EMD69710.1 - 9.5e-32 110.3 0.1 2.1e-31 109.1 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF1009 PF06230.6 EMD69710.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) Oxysterol_BP PF01237.13 EMD69711.1 - 2.1e-92 309.3 0.0 3e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein TP1 PF02079.11 EMD69713.1 - 0.14 11.9 0.5 0.14 11.9 0.3 1.5 2 0 0 2 2 2 0 Nuclear transition protein 1 Myb_DNA-bind_6 PF13921.1 EMD69715.1 - 4.5e-15 55.4 0.6 1.7e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMD69715.1 - 7.5e-11 41.9 0.1 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DNA_ligase_A_C PF04679.10 EMD69715.1 - 0.015 15.7 0.2 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Spt20 PF12090.3 EMD69715.1 - 0.036 13.4 2.3 0.056 12.7 1.6 1.4 1 0 0 1 1 1 0 Spt20 family PKI PF02827.11 EMD69715.1 - 0.067 13.3 4.8 0.14 12.2 3.3 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Suf PF05843.9 EMD69715.1 - 0.17 11.5 5.5 0.29 10.8 3.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OmpH PF03938.9 EMD69715.1 - 0.61 9.9 14.1 0.95 9.3 9.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4175 PF13779.1 EMD69715.1 - 3.7 5.1 18.5 6.2 4.3 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Myb_DNA-binding PF00249.26 EMD69716.1 - 7.6e-12 45.0 1.4 1.2e-06 28.5 0.5 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMD69716.1 - 8.6e-11 41.7 0.6 1.6e-06 28.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 EMD69716.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PAT1 PF09770.4 EMD69716.1 - 9.8 4.2 9.1 11 4.0 6.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SP_C-Propep PF08999.5 EMD69717.1 - 0.00023 20.5 8.4 0.00042 19.7 5.3 1.8 2 0 0 2 2 2 1 Surfactant protein C, N terminal propeptide Shisa PF13908.1 EMD69717.1 - 0.021 15.0 12.8 0.14 12.3 2.2 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator T2SF PF00482.18 EMD69717.1 - 1 9.3 2.8 1.8 8.4 2.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Renin_r PF07850.9 EMD69717.1 - 1.2 9.5 4.7 1.1 9.6 2.3 1.6 2 0 0 2 2 2 0 Renin receptor-like protein EphA2_TM PF14575.1 EMD69717.1 - 6 7.3 9.0 19 5.7 6.2 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-bind_6 PF13921.1 EMD69718.1 - 4.3e-07 29.9 0.1 0.00016 21.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMD69718.1 - 0.0063 16.5 0.7 0.025 14.6 0.6 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ATPase_gene1 PF09527.5 EMD69719.1 - 0.0099 15.6 2.1 0.013 15.2 0.9 1.6 1 1 1 2 2 2 1 Putative F0F1-ATPase subunit (ATPase_gene1) TrkH PF02386.11 EMD69720.1 - 1.2e-81 274.0 9.3 4.1e-81 272.3 2.9 2.5 2 1 0 2 2 2 2 Cation transport protein MFS_1 PF07690.11 EMD69721.1 - 7.7e-31 107.0 29.8 7.1e-21 74.2 3.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69721.1 - 7.4e-10 37.9 1.5 7.4e-10 37.9 1.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter GPI-anchored PF10342.4 EMD69723.1 - 1.3e-20 73.6 0.2 2.3e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cellulase PF00150.13 EMD69724.1 - 2.7e-14 53.0 1.4 3.3e-14 52.7 0.0 1.8 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EMD69724.1 - 0.00044 19.4 0.1 0.041 12.9 0.2 2.2 1 1 1 2 2 2 2 Beta-galactosidase TENA_THI-4 PF03070.11 EMD69725.1 - 1e-05 25.3 0.0 2.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family zf-BED PF02892.10 EMD69725.1 - 0.0015 18.2 1.0 0.0015 18.2 0.7 2.1 2 0 0 2 2 2 1 BED zinc finger PNP_UDP_1 PF01048.15 EMD69726.1 - 2e-10 40.0 0.4 4.3e-10 38.9 0.3 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EMD69726.1 - 9e-06 25.4 0.1 2.5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMD69726.1 - 1e-05 25.6 0.1 0.00029 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMD69726.1 - 7.3e-05 21.9 2.7 0.00046 19.2 0.1 2.3 1 1 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.1 EMD69726.1 - 9e-05 22.5 0.1 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EMD69726.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD69726.1 - 0.05 13.7 0.0 0.53 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF3962 PF13111.1 EMD69726.1 - 0.051 12.9 0.1 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) NB-ARC PF00931.17 EMD69726.1 - 0.075 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Ank PF00023.25 EMD69727.1 - 2.2e-27 93.4 8.9 9.1e-08 31.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMD69727.1 - 1.1e-25 89.7 2.3 9.4e-18 64.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD69727.1 - 1.5e-23 82.7 7.0 3.4e-09 36.9 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMD69727.1 - 6.1e-16 58.0 4.2 9.5e-05 22.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD69727.1 - 4.7e-15 54.2 2.2 0.00094 19.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat YajC PF02699.10 EMD69727.1 - 0.067 12.8 1.0 4.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Preprotein translocase subunit DUF3219 PF11514.3 EMD69727.1 - 0.12 12.2 0.0 41 4.1 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3219) DUF1843 PF08898.5 EMD69727.1 - 0.12 12.4 1.7 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Turandot PF07240.6 EMD69727.1 - 0.12 11.8 0.6 60 3.2 0.0 3.2 1 1 2 3 3 3 0 Stress-inducible humoral factor Turandot ApbA PF02558.11 EMD69727.1 - 1.8 7.9 6.0 6.5 6.1 0.2 2.8 1 1 2 3 3 3 0 Ketopantoate reductase PanE/ApbA HET PF06985.6 EMD69728.1 - 8.3e-22 77.8 0.0 1.4e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EMD69729.1 - 3.5e-80 269.7 27.9 4.3e-80 269.4 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69729.1 - 5.3e-14 51.6 31.3 5.3e-14 51.6 21.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SAGA-Tad1 PF12767.2 EMD69730.1 - 0.004 16.8 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit AAA PF00004.24 EMD69732.1 - 1.4e-17 64.1 0.0 3.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMD69732.1 - 0.0001 22.4 0.9 0.016 15.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EMD69732.1 - 0.00021 22.1 0.0 0.00078 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD69732.1 - 0.00053 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMD69732.1 - 0.0078 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMD69732.1 - 0.0088 15.9 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMD69732.1 - 0.0097 16.2 0.0 0.037 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMD69732.1 - 0.014 15.3 0.4 0.065 13.2 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain KaiC PF06745.8 EMD69732.1 - 0.027 13.5 0.3 0.55 9.3 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.1 EMD69732.1 - 0.062 13.1 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMD69732.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AIRS_C PF02769.17 EMD69733.1 - 4.6e-32 111.1 0.0 8.8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMD69733.1 - 2.2e-16 59.8 2.4 2.9e-16 59.4 0.6 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.21 EMD69733.1 - 3.9e-14 52.4 0.0 1.3e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMD69733.1 - 0.0064 16.6 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Pribosyltran PF00156.22 EMD69734.1 - 1.8e-15 56.7 0.0 2.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMD69734.1 - 0.0064 15.7 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribonuc_L-PSP PF01042.16 EMD69735.1 - 5.1e-39 132.7 0.0 5.7e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.17 EMD69736.1 - 7.6e-58 196.1 0.0 9.9e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S9 PF00326.16 EMD69737.1 - 1.4e-44 151.8 0.9 2.1e-44 151.3 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMD69737.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EMD69737.1 - 0.00085 18.9 1.0 0.085 12.5 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Corona_nucleoca PF00937.13 EMD69737.1 - 0.014 14.3 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TRP PF06011.7 EMD69738.1 - 4.6e-89 298.9 25.6 1.4e-88 297.4 17.8 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMD69738.1 - 1.9e-23 83.0 0.1 2.9e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 ML-like domain FYVE PF01363.16 EMD69739.1 - 3.9e-22 77.9 0.7 3.9e-22 77.9 0.5 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EMD69739.1 - 1e-08 34.8 3.3 1e-08 34.8 2.3 3.5 3 0 0 3 3 3 2 Ring finger domain Rad50_zn_hook PF04423.9 EMD69739.1 - 0.0031 16.9 4.0 0.71 9.3 0.2 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif FYVE_2 PF02318.11 EMD69739.1 - 0.0041 16.9 1.6 0.0041 16.9 1.1 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 EMD69739.1 - 0.013 15.5 3.1 0.013 15.5 2.1 3.7 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMD69739.1 - 0.014 15.0 1.4 0.014 15.0 1.0 3.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD69739.1 - 0.27 11.3 14.9 0.05 13.7 2.7 3.3 3 0 0 3 3 3 0 RING-H2 zinc finger FANCL_C PF11793.3 EMD69739.1 - 7.3 6.6 11.4 0.48 10.4 1.9 2.9 3 0 0 3 3 3 0 FANCL C-terminal domain Glyco_hydro_18 PF00704.23 EMD69740.1 - 6.8e-31 107.9 0.1 2e-30 106.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_2 PF02230.11 EMD69741.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMD69741.1 - 0.038 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAS PF03059.11 EMD69742.1 - 8.3e-69 231.8 0.0 9.8e-69 231.5 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EMD69742.1 - 5.3e-07 29.3 0.0 9.4e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD69742.1 - 0.022 15.3 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMD69742.1 - 0.063 13.3 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EMD69742.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Amidohydro_3 PF07969.6 EMD69743.1 - 5.5e-62 210.2 0.0 6.7e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EMD69743.1 - 1.6e-07 31.3 0.0 8.9e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMD69743.1 - 0.00022 21.3 0.2 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EMD69743.1 - 0.0037 17.0 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase CorA PF01544.13 EMD69744.1 - 1.3e-11 44.0 2.2 2.2e-11 43.3 0.1 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2635 PF10948.3 EMD69744.1 - 0.14 11.4 1.5 0.29 10.4 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) THOC7 PF05615.8 EMD69744.1 - 1.1 9.5 6.1 2.7 8.2 0.4 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 GMC_oxred_N PF00732.14 EMD69746.1 - 1.6e-62 211.3 0.0 2.1e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD69746.1 - 4.4e-31 108.1 0.0 1.1e-30 106.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EMD69746.1 - 3.2e-08 32.8 0.1 0.00017 20.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMD69746.1 - 8.2e-07 29.2 0.1 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMD69746.1 - 1.3e-05 24.2 0.2 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMD69746.1 - 6.4e-05 22.9 0.1 0.097 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD69746.1 - 8.4e-05 22.5 0.3 0.0003 20.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMD69746.1 - 0.0022 17.0 0.0 0.0069 15.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMD69746.1 - 0.015 15.7 0.2 0.051 13.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMD69746.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMD69746.1 - 0.038 12.4 0.0 0.2 10.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EMD69746.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain eRF1_1 PF03463.10 EMD69747.1 - 1.4e-45 154.1 0.2 2.8e-45 153.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EMD69747.1 - 3.7e-17 62.9 0.0 2e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 EMD69747.1 - 2.1e-14 53.7 0.0 3.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 MOZART1 PF12554.3 EMD69748.1 - 4e-24 83.8 0.6 4.8e-24 83.5 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Acetyltransf_1 PF00583.19 EMD69749.1 - 7.6e-06 25.8 0.3 2e-05 24.5 0.2 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD69749.1 - 0.00024 21.2 0.0 0.00071 19.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EMD69749.1 - 0.012 14.5 0.1 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Pkinase PF00069.20 EMD69751.1 - 2.3e-59 200.6 0.0 3.9e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD69751.1 - 5.9e-23 81.2 0.0 1.4e-22 80.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMD69751.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMD69751.1 - 0.0084 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SAB PF04382.8 EMD69751.1 - 0.013 15.1 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 SAB domain Svf1 PF08622.5 EMD69752.1 - 6.8e-127 422.9 0.1 7.8e-127 422.7 0.1 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EMD69752.1 - 0.014 14.6 0.8 0.017 14.4 0.1 1.5 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) Histone PF00125.19 EMD69753.1 - 0.0015 18.6 0.2 0.002 18.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_mis_repair PF01119.14 EMD69755.1 - 4e-34 116.6 0.0 6.5e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMD69755.1 - 2.2e-14 53.2 0.0 5.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMD69755.1 - 1.4e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sin_N PF04801.8 EMD69756.1 - 1.6e-25 89.8 3.9 1.2e-24 86.9 2.7 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region MMS1_N PF10433.4 EMD69757.1 - 8.6e-105 350.7 0.0 1.7e-104 349.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EMD69757.1 - 4.5e-77 259.2 0.0 1.4e-74 251.1 0.0 3.2 4 0 0 4 4 4 2 CPSF A subunit region PAM2 PF07145.10 EMD69758.1 - 0.06 12.8 3.0 0.14 11.6 2.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Baculo_helicase PF04735.7 EMD69758.1 - 0.42 7.8 4.7 0.58 7.4 3.3 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase EmrE PF13536.1 EMD69759.1 - 0.001 19.2 7.0 0.001 19.2 4.9 1.9 1 1 1 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EMD69759.1 - 0.025 14.6 20.9 0.17 11.9 13.9 2.0 1 1 1 2 2 2 0 EamA-like transporter family UPF0546 PF10639.4 EMD69759.1 - 0.14 12.0 5.2 0.23 11.3 3.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EMD69759.1 - 0.79 9.3 10.7 1.4 8.5 7.4 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family TFIIA_gamma_C PF02751.9 EMD69760.1 - 1.4e-27 95.2 2.1 2e-27 94.7 1.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EMD69760.1 - 4.3e-25 87.0 0.2 6e-25 86.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MoCF_biosynth PF00994.19 EMD69761.1 - 5.8e-56 187.9 0.2 3.5e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EMD69761.1 - 7.1e-35 119.7 1.9 1.1e-34 119.0 1.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) ATP-synt_C PF00137.16 EMD69761.1 - 1.5e-26 92.0 22.6 7.5e-16 57.7 4.1 2.6 2 0 0 2 2 2 2 ATP synthase subunit C MoeA_C PF03454.10 EMD69761.1 - 2.5e-17 62.5 0.0 7.4e-17 61.0 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF1043 PF06295.7 EMD69763.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF1191 PF06697.7 EMD69763.1 - 0.015 14.0 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1049 PF06305.6 EMD69763.1 - 0.015 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF543 PF04418.7 EMD69763.1 - 0.034 14.0 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) I-set PF07679.11 EMD69763.1 - 0.17 11.7 0.6 0.32 10.8 0.1 1.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain SET PF00856.23 EMD69764.1 - 3.1e-14 53.6 0.0 8.7e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 SET domain TRAUB PF08164.7 EMD69764.1 - 0.12 12.4 0.1 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal TPR_12 PF13424.1 EMD69765.1 - 1.2e-10 41.1 0.8 0.17 11.8 0.0 7.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD69765.1 - 9.2e-09 35.1 19.4 2.2 9.1 0.0 10.8 10 3 3 13 13 12 2 Tetratricopeptide repeat Suf PF05843.9 EMD69765.1 - 2.5e-08 34.0 8.3 0.029 14.0 0.0 5.5 3 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EMD69765.1 - 8.7e-08 31.6 3.8 0.62 9.7 0.0 7.4 8 1 0 8 8 8 2 TPR repeat TPR_15 PF13429.1 EMD69765.1 - 1.3e-06 27.6 4.6 0.00032 19.8 0.4 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD69765.1 - 1.7e-06 28.2 0.6 2.8 8.3 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMD69765.1 - 3.7e-06 26.4 19.3 0.035 14.0 0.0 7.6 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69765.1 - 3.7e-05 24.2 6.8 3.3 8.4 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69765.1 - 0.00011 21.7 4.4 0.36 10.7 0.0 6.5 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69765.1 - 0.00019 20.9 9.0 0.053 13.3 0.0 5.5 7 0 0 7 7 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMD69765.1 - 0.00021 21.0 12.0 1.1 8.9 0.1 6.8 6 1 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 EMD69765.1 - 0.0012 18.8 3.7 1 9.7 0.0 5.3 8 0 0 8 8 6 1 Tetratricopeptide repeat RPN7 PF10602.4 EMD69765.1 - 0.006 15.9 1.3 0.016 14.5 0.2 2.4 3 1 0 3 3 3 1 26S proteasome subunit RPN7 HAT PF02184.11 EMD69765.1 - 0.0088 15.7 2.3 2.4 7.9 0.0 5.4 5 0 0 5 5 5 1 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 EMD69765.1 - 0.0091 16.3 5.9 8.2 7.1 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat CKAP2_C PF15297.1 EMD69765.1 - 0.016 14.0 0.9 0.056 12.2 0.3 2.1 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus TPR_10 PF13374.1 EMD69765.1 - 0.53 10.2 4.4 15 5.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 EMD69766.1 - 1.3e-65 220.5 4.5 2.1e-65 219.9 3.1 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Viral_P18 PF04521.8 EMD69766.1 - 2 7.9 7.6 2.7 7.4 0.2 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RNase_H2-Ydr279 PF09468.5 EMD69766.1 - 3.2 6.8 7.9 4.6 6.3 5.5 1.5 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ribosomal_L6e PF01159.14 EMD69766.1 - 8.8 6.6 10.5 2.7 8.2 4.5 2.2 2 1 1 3 3 3 0 Ribosomal protein L6e RRM_1 PF00076.17 EMD69767.1 - 1.2e-22 79.2 2.0 2.3e-10 39.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMD69767.1 - 8.4e-15 54.5 0.7 1.2e-06 28.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMD69767.1 - 1.1e-11 44.3 0.4 6.3e-07 29.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EMD69767.1 - 0.00038 20.0 0.7 0.01 15.4 0.0 2.4 2 1 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 EMD69767.1 - 0.075 12.7 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 MFS_1 PF07690.11 EMD69768.1 - 8.2e-44 149.7 24.2 1.2e-38 132.7 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMD69768.1 - 0.00063 19.4 2.3 0.037 13.8 0.3 3.3 3 0 0 3 3 3 1 MFS_1 like family MFS_2 PF13347.1 EMD69768.1 - 0.007 14.8 17.8 0.063 11.6 6.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein KRTAP PF11759.3 EMD69769.1 - 5.6 7.2 10.2 16 5.8 7.1 1.9 1 1 0 1 1 1 0 Keratin-associated matrix Cu-oxidase PF00394.17 EMD69770.1 - 3.6e-31 108.2 0.0 1.3e-28 99.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMD69770.1 - 8.8e-25 86.7 2.6 3.1e-24 84.9 0.2 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMD69770.1 - 9.9e-21 73.6 12.3 2.1e-20 72.6 1.6 3.4 2 1 0 2 2 2 1 Multicopper oxidase PAPS_reduct PF01507.14 EMD69773.1 - 1.1e-28 100.2 0.0 5e-19 68.7 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ImpA-rel_N PF06812.7 EMD69773.1 - 0.082 12.6 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 ImpA-related N-terminal NIR_SIR PF01077.17 EMD69774.1 - 8.6e-53 177.8 0.0 6.2e-46 155.6 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EMD69774.1 - 9.2e-32 108.4 0.0 1e-15 57.0 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EMD69774.1 - 1.3e-25 90.0 0.0 3.5e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EMD69774.1 - 1.9e-10 40.6 1.4 2.4e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TraF PF13728.1 EMD69774.1 - 0.026 14.0 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein Ehbp PF10622.4 EMD69774.1 - 0.18 11.7 0.1 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) PNPOx_C PF10590.4 EMD69775.1 - 6.3e-21 73.5 1.3 6.3e-21 73.5 0.9 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EMD69775.1 - 6.3e-17 61.3 0.0 9.2e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EMD69775.1 - 0.014 15.7 0.1 0.027 14.7 0.1 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TPR_2 PF07719.12 EMD69776.1 - 4e-12 45.0 12.2 0.001 18.7 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMD69776.1 - 5.7e-11 42.7 11.4 0.11 13.1 1.3 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMD69776.1 - 5.3e-10 38.7 9.1 0.0005 19.6 0.0 5.6 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.1 EMD69776.1 - 2.4e-09 37.3 6.7 0.054 13.8 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMD69776.1 - 8.7e-08 31.4 10.3 0.083 12.5 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMD69776.1 - 5.9e-07 29.3 6.2 0.17 11.8 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD69776.1 - 5.7e-06 26.4 11.7 4 8.3 0.0 7.7 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMD69776.1 - 4.4e-05 22.9 3.2 1.1 9.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMD69776.1 - 8.4e-05 22.0 4.8 1.9 8.4 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD69776.1 - 0.00018 21.4 1.0 10 6.6 0.0 5.7 7 1 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD69776.1 - 0.0019 18.2 2.9 0.17 12.0 0.0 4.7 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMD69776.1 - 0.0022 17.7 0.8 6.8 6.6 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 EMD69776.1 - 2.3 8.6 5.3 3.8 8.0 0.3 4.0 5 1 1 6 6 3 0 Pentatricopeptide repeat domain TPR_4 PF07721.9 EMD69776.1 - 6.6 7.4 13.5 12 6.7 0.5 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EMD69778.1 - 2.7e-67 226.7 0.0 3.5e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Menin PF05053.8 EMD69778.1 - 2.5 6.1 4.3 3.4 5.7 3.0 1.1 1 0 0 1 1 1 0 Menin FAM60A PF15396.1 EMD69778.1 - 8.7 6.0 6.9 46 3.6 4.8 2.0 1 1 0 1 1 1 0 Protein Family FAM60A PAP2 PF01569.16 EMD69779.1 - 3.4e-18 65.5 2.6 3.4e-18 65.5 1.8 2.0 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 EMD69780.1 - 3.1e-48 163.2 0.0 4.3e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD69780.1 - 9.2e-11 42.2 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD69780.1 - 6.5e-06 25.4 0.0 1.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family DASH_Dad1 PF08649.5 EMD69781.1 - 1.5e-26 91.8 0.9 1.8e-26 91.5 0.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 EMD69781.1 - 0.068 12.8 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 WVELL protein PilJ PF13675.1 EMD69781.1 - 0.085 13.1 0.5 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term tRNA_int_endo PF01974.12 EMD69782.1 - 1.7e-12 46.9 0.0 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MscS_TM PF12794.2 EMD69782.1 - 0.32 9.5 0.3 0.44 9.1 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Wyosine_form PF08608.7 EMD69783.1 - 2.6e-22 78.7 0.0 5.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 EMD69783.1 - 1.4e-21 77.3 0.1 3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 EMD69783.1 - 3.1e-09 36.9 0.8 4.5e-08 33.1 0.5 2.5 1 1 0 1 1 1 1 Flavodoxin ADH_zinc_N PF00107.21 EMD69785.1 - 7.3e-29 99.9 0.3 1.1e-28 99.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMD69785.1 - 1.7e-13 51.6 0.0 4.8e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMD69785.1 - 3.7e-13 49.1 0.3 1.4e-12 47.3 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EMD69785.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EMD69785.1 - 0.026 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Peptidase_C48 PF02902.14 EMD69786.1 - 6.7e-17 61.8 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.23 EMD69787.1 - 1e-43 149.0 0.9 1.3e-43 148.7 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cu_bind_like PF02298.12 EMD69789.1 - 0.012 15.3 0.3 0.03 14.1 0.2 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Sec7 PF01369.15 EMD69790.1 - 1.9e-65 220.0 0.0 3.3e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EMD69790.1 - 5.1e-18 65.0 0.0 5.5e-13 48.6 0.1 3.0 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 EMD69791.1 - 2.4e-121 403.9 0.0 4.7e-121 403.0 0.0 1.4 1 0 0 1 1 1 1 Anp1 DUF3849 PF12960.2 EMD69791.1 - 0.049 13.5 2.3 0.097 12.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DUF2146 PF10220.4 EMD69791.1 - 1.7 6.5 9.2 2.1 6.2 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RNase_PH PF01138.16 EMD69792.1 - 7.8e-24 84.4 0.0 1.7e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_hydro_72 PF03198.9 EMD69793.1 - 2.9e-115 384.5 0.8 3.6e-115 384.2 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMD69793.1 - 0.0052 16.0 0.2 0.012 14.8 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TAP42 PF04177.7 EMD69793.1 - 0.1 11.4 0.1 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 TAP42-like family Ribonuclease_3 PF00636.21 EMD69794.1 - 5.9e-38 129.8 0.0 3.4e-18 66.1 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 EMD69794.1 - 2.8e-20 71.8 0.1 4.1e-19 68.1 0.0 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EMD69794.1 - 3.9e-16 59.1 0.0 2.1e-07 30.9 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.26 EMD69794.1 - 2.2e-14 53.0 0.1 5.4e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD69794.1 - 1.2e-11 44.3 0.0 1.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMD69794.1 - 1.9e-09 37.6 0.0 2.1e-08 34.2 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TAP42 PF04177.7 EMD69795.1 - 5.7e-102 341.1 0.5 6.4e-102 340.9 0.4 1.0 1 0 0 1 1 1 1 TAP42-like family Lipase_GDSL_2 PF13472.1 EMD69796.1 - 6.5e-17 62.2 0.0 1.2e-16 61.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD69796.1 - 7.6e-15 55.3 0.0 9.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_71 PF03659.9 EMD69798.1 - 1.5e-58 198.1 0.1 1.8e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Hamartin PF04388.7 EMD69799.1 - 6.5e-42 144.0 9.4 1.4e-41 143.0 6.5 1.5 1 0 0 1 1 1 1 Hamartin protein DUF812 PF05667.6 EMD69799.1 - 1.8 6.9 30.0 4.3 5.7 20.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.16 EMD69800.1 - 0.0043 16.5 6.5 0.0069 15.8 4.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein Asp-B-Hydro_N PF05279.6 EMD69800.1 - 0.24 11.1 4.3 0.35 10.6 3.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lzipper-MIP1 PF14389.1 EMD69800.1 - 0.74 9.9 9.2 0.13 12.3 2.5 2.3 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Rrn6 PF10214.4 EMD69801.1 - 4.3e-125 418.6 0.0 5.4e-125 418.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF3237 PF11578.3 EMD69801.1 - 3.4e-35 120.5 0.1 5.3e-35 119.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NARP1 PF12569.3 EMD69801.1 - 0.23 10.1 3.1 11 4.6 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Spindle_Spc25 PF08234.7 EMD69802.1 - 3.2e-25 87.9 1.3 1.4e-24 85.8 0.1 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 MtlR PF05068.7 EMD69802.1 - 0.059 12.8 0.2 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Mannitol repressor Tht1 PF04163.7 EMD69802.1 - 0.57 8.5 2.7 0.73 8.1 1.9 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein TMPIT PF07851.8 EMD69802.1 - 1.4 7.9 7.1 1.9 7.4 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.7 EMD69802.1 - 1.7 6.9 4.8 1.9 6.8 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 EMD69802.1 - 1.8 7.4 13.2 2.8 6.7 9.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1843 PF08898.5 EMD69802.1 - 2.3 8.3 5.9 3.3 7.8 2.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) AAA_23 PF13476.1 EMD69802.1 - 5.4 7.2 7.2 2.6 8.3 3.1 1.7 2 0 0 2 2 2 0 AAA domain HA2 PF04408.18 EMD69803.1 - 1e-20 73.6 0.1 2.1e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMD69803.1 - 6.9e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMD69803.1 - 5.1e-11 42.2 0.0 1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD69803.1 - 1.7e-06 27.6 0.1 3.7e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMD69803.1 - 3e-06 27.3 0.1 9.1e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMD69803.1 - 0.0041 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 EMD69803.1 - 0.069 12.5 0.1 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EMD69803.1 - 0.069 13.4 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EMD69803.1 - 0.075 11.9 0.0 0.18 10.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 EMD69803.1 - 0.11 11.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EMD69803.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.1 EMD69804.1 - 3.5e-07 30.2 0.9 1.9e-06 27.9 0.6 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMD69804.1 - 4.1e-06 26.2 1.5 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMD69804.1 - 7.2e-06 24.9 1.7 5.3e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMD69804.1 - 8.9e-06 25.2 0.9 1.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMD69804.1 - 0.00013 21.0 0.1 0.00043 19.4 0.1 1.8 1 0 0 1 1 1 1 EF hand PAXNEB PF05625.6 EMD69805.1 - 5.7e-112 374.1 0.0 6.3e-112 374.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein WD40 PF00400.27 EMD69806.1 - 1.1e-18 66.3 1.0 0.00053 19.7 0.3 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ATP_bind_1 PF03029.12 EMD69807.1 - 5.2e-75 252.0 0.0 1.6e-74 250.4 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EMD69807.1 - 0.00081 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EMD69807.1 - 0.0033 18.2 0.2 0.0033 18.2 0.2 2.7 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMD69807.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 EMD69807.1 - 0.02 13.6 0.0 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 EMD69807.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EMD69807.1 - 0.032 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EMD69807.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMD69807.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EMD69807.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Trypan_PARP PF05887.6 EMD69807.1 - 0.12 12.1 3.1 0.22 11.3 2.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Fer4_NifH PF00142.13 EMD69807.1 - 0.19 10.8 0.3 3.2 6.8 0.2 2.2 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Snf7 PF03357.16 EMD69808.1 - 2.4e-19 69.3 10.8 2.4e-19 69.3 7.5 1.9 1 1 1 2 2 2 1 Snf7 SKIP_SNW PF02731.10 EMD69808.1 - 0.35 10.3 17.6 0.26 10.7 1.4 2.4 2 0 0 2 2 2 0 SKIP/SNW domain Bac_globin PF01152.16 EMD69808.1 - 0.39 10.7 2.8 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial-like globin ESSS PF10183.4 EMD69809.1 - 3.4e-28 98.1 0.4 4e-28 97.8 0.3 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_7 PF00840.15 EMD69810.1 - 4e-209 694.3 21.6 4.6e-209 694.1 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CarbpepA_inh PF02977.10 EMD69811.1 - 0.082 12.4 1.8 0.18 11.4 1.2 1.5 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Kei1 PF08552.6 EMD69812.1 - 5.1e-46 156.7 0.8 6.9e-46 156.2 0.6 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 PqiA PF04403.8 EMD69812.1 - 0.029 13.9 0.6 0.057 12.9 0.4 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A SUV3_C PF12513.3 EMD69814.1 - 2.5e-18 65.2 0.4 2.5e-18 65.2 0.3 2.3 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EMD69814.1 - 4.2e-10 39.3 0.0 8.9e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.18 EMD69815.1 - 2.8e-137 458.7 0.0 3.3e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DIM1 PF02966.11 EMD69816.1 - 1.8e-61 205.4 0.1 2.1e-61 205.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EMD69816.1 - 0.0081 15.8 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Tnp_DNA_bind PF14706.1 EMD69817.1 - 0.23 11.2 0.9 0.41 10.3 0.2 1.8 2 0 0 2 2 2 0 Transposase DNA-binding DUF2477 PF10631.4 EMD69817.1 - 0.23 11.6 1.5 0.31 11.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) F-box-like PF12937.2 EMD69818.1 - 1.4e-08 34.3 0.0 3.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD69818.1 - 9.4e-08 31.5 0.3 2.9e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain Ribosom_S12_S23 PF00164.20 EMD69819.1 - 2.7e-42 143.0 1.9 3.4e-42 142.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NAD_binding_2 PF03446.10 EMD69820.1 - 3.3e-39 134.3 0.1 5e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD69820.1 - 3.3e-29 101.4 0.1 5.3e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EMD69820.1 - 0.00017 20.4 0.0 0.00036 19.4 0.0 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EMD69820.1 - 0.00028 21.2 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMD69820.1 - 0.00076 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EMD69820.1 - 0.0023 18.4 0.0 0.0047 17.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DSPc PF00782.15 EMD69821.1 - 5.4e-29 100.4 0.0 7.7e-22 77.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMD69821.1 - 0.00012 21.5 0.0 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMD69821.1 - 0.089 12.8 0.1 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate DNA_pol_delta_4 PF04081.8 EMD69822.1 - 4.9e-26 91.4 0.8 7.3e-26 90.8 0.5 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DcpS_C PF11969.3 EMD69823.1 - 1.4e-29 102.7 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EMD69823.1 - 2.3e-26 92.3 0.0 3.7e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Git3 PF11710.3 EMD69824.1 - 2.2e-26 92.6 6.6 2.2e-26 92.6 4.5 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMD69824.1 - 9.9e-21 73.3 3.4 9.9e-21 73.3 2.4 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_C12 PF01088.16 EMD69825.1 - 4e-66 222.2 0.0 4.5e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 tRNA_bind PF01588.15 EMD69826.1 - 4.7e-22 77.6 0.1 4.1e-21 74.6 0.1 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EMD69826.1 - 2.3e-08 34.4 0.0 5.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMD69826.1 - 0.00084 19.1 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMD69826.1 - 0.015 15.2 0.0 0.061 13.3 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Med3 PF11593.3 EMD69826.1 - 2.8 7.1 8.0 4.9 6.2 5.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sad1_UNC PF07738.8 EMD69827.1 - 3.2e-20 72.3 0.0 4.2e-19 68.6 0.0 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Epimerase PF01370.16 EMD69828.1 - 6.3e-43 146.8 0.0 9.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMD69828.1 - 4.7e-26 90.5 0.1 8.6e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EMD69828.1 - 1.8e-16 59.7 0.1 7e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMD69828.1 - 6e-13 48.3 0.0 5.2e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMD69828.1 - 9.7e-13 47.6 0.0 1.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMD69828.1 - 3e-11 43.5 0.0 4.9e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69828.1 - 2e-07 30.8 0.0 4.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMD69828.1 - 2.9e-07 30.6 0.0 5.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMD69828.1 - 5.3e-05 22.2 0.0 0.0011 18.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Methyltransf_18 PF12847.2 EMD69828.1 - 0.0015 19.0 0.0 0.59 10.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 EMD69828.1 - 0.003 16.8 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 EMD69828.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 EMD69828.1 - 0.046 13.0 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EMD69828.1 - 0.075 11.9 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phage_lysozyme PF00959.14 EMD69828.1 - 0.089 13.0 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Phage lysozyme MCM PF00493.18 EMD69829.1 - 1.7e-137 457.6 0.4 1.7e-137 457.6 0.3 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EMD69829.1 - 1.1e-20 74.3 1.5 1.9e-20 73.5 0.0 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMD69829.1 - 2.1e-08 33.6 0.8 7.5e-07 28.5 0.0 2.9 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMD69829.1 - 0.00098 18.6 0.0 0.0026 17.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EMD69829.1 - 0.0014 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD69829.1 - 0.0058 16.3 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HA2 PF04408.18 EMD69830.1 - 2.5e-28 98.0 0.1 9.2e-28 96.2 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMD69830.1 - 1.1e-26 92.9 0.0 3.4e-26 91.3 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 EMD69830.1 - 1.6e-12 47.3 0.4 3.8e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 EMD69830.1 - 1.7e-11 43.7 0.0 5.5e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMD69830.1 - 9.2e-06 25.2 0.1 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EMD69830.1 - 2.4e-05 23.3 0.0 8.4e-05 21.5 0.0 1.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.1 EMD69830.1 - 3.6e-05 23.9 0.1 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMD69830.1 - 0.01 15.4 0.0 0.038 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMD69830.1 - 0.011 15.6 0.1 0.17 11.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD69830.1 - 0.019 14.7 0.4 0.045 13.4 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain RimM PF01782.13 EMD69830.1 - 0.035 14.0 0.1 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 RimM N-terminal domain SRP54 PF00448.17 EMD69830.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.10 EMD69830.1 - 0.11 10.4 0.1 0.18 9.6 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein TauD PF02668.11 EMD69832.1 - 4e-51 174.1 0.1 5.7e-51 173.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_15 PF01793.11 EMD69833.1 - 1.2e-141 471.4 8.9 1.4e-141 471.2 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 EMD69834.1 - 5.5e-246 818.7 76.0 1.7e-244 813.8 52.7 2.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Asp PF00026.18 EMD69835.1 - 6.9e-67 225.9 5.9 8.2e-67 225.6 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMD69835.1 - 3.1e-07 30.7 2.2 0.00062 20.2 0.7 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EMD69835.1 - 9.9e-06 25.5 0.0 0.00023 21.1 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMD69835.1 - 0.059 12.9 0.5 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal UL73_N PF12522.3 EMD69835.1 - 0.58 9.7 5.1 1.5 8.4 3.5 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DUF775 PF05603.7 EMD69837.1 - 4e-54 183.2 0.0 4.7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) HD PF01966.17 EMD69838.1 - 1.1e-10 41.6 0.1 2.2e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 EMD69838.1 - 0.0038 16.5 0.1 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 HDOD domain Asparaginase PF00710.15 EMD69839.1 - 8.2e-65 218.7 0.4 9.7e-65 218.4 0.3 1.0 1 0 0 1 1 1 1 Asparaginase DUF3608 PF12257.3 EMD69840.1 - 1.5e-77 260.2 0.0 2.2e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EMD69840.1 - 4.5e-27 93.5 0.2 9.8e-27 92.5 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NAD_binding_10 PF13460.1 EMD69841.1 - 4.8e-14 52.7 0.6 2.5e-13 50.4 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMD69841.1 - 0.0038 16.6 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMD69841.1 - 0.0047 15.8 0.0 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EMD69841.1 - 0.012 15.5 0.1 0.023 14.5 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase SgrR_N PF12793.2 EMD69841.1 - 0.093 12.7 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term E1-E2_ATPase PF00122.15 EMD69842.1 - 3.6e-59 199.5 2.4 9.2e-59 198.2 1.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMD69842.1 - 3.6e-46 156.9 9.9 3.6e-46 156.9 6.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMD69842.1 - 6.2e-28 98.6 0.0 3.6e-27 96.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMD69842.1 - 7.7e-17 61.0 0.0 1.9e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMD69842.1 - 1.7e-14 54.4 0.0 3.5e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMD69842.1 - 2e-07 30.3 0.0 1.8e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMD69842.1 - 2.6e-07 30.5 0.1 2.8e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EMD69842.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) KAR9 PF08580.5 EMD69842.1 - 7.2 4.7 6.4 0.89 7.7 0.0 2.2 2 0 0 2 2 2 0 Yeast cortical protein KAR9 MFS_1 PF07690.11 EMD69843.1 - 7.4e-39 133.4 55.8 9.4e-32 110.0 20.6 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD69843.1 - 4.1e-07 28.5 21.4 5.4e-07 28.2 14.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.1 EMD69843.1 - 0.086 12.2 3.4 0.46 9.8 0.9 2.7 2 0 0 2 2 2 0 Neurensin GATase PF00117.23 EMD69844.1 - 1.6e-10 40.7 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EMD69844.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EMD69844.1 - 0.0085 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase UPF0180 PF03698.8 EMD69844.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) GDA1_CD39 PF01150.12 EMD69845.1 - 1.4e-106 356.6 0.0 1.9e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Rifin_STEVOR PF02009.11 EMD69845.1 - 3.7 7.1 5.6 0.31 10.6 0.3 1.7 2 0 0 2 2 2 0 Rifin/stevor family F-box PF00646.28 EMD69846.1 - 0.065 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 F-box domain RNA_pol_Rpb8 PF03870.10 EMD69847.1 - 3.8e-33 114.5 0.1 4.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EMD69848.1 - 3.9e-09 36.2 0.1 6.4e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain PHB_depo_C PF06850.6 EMD69848.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Met_10 PF02475.11 EMD69849.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FNIP_N PF14636.1 EMD69850.1 - 3e-32 111.8 0.0 3e-32 111.8 0.0 4.6 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EMD69850.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain GST_N_2 PF13409.1 EMD69851.1 - 3.3e-21 75.0 0.0 9.1e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMD69851.1 - 1.9e-13 50.1 0.0 5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMD69851.1 - 4.5e-06 26.7 0.1 9.5e-05 22.5 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMD69851.1 - 0.00027 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMD69851.1 - 0.0043 17.4 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2317 PF10079.4 EMD69851.1 - 0.027 13.0 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Nucleoporin_FG PF13634.1 EMD69852.1 - 2.2e-15 56.8 74.1 4.2e-09 36.6 26.7 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF1515 PF07439.6 EMD69852.1 - 0.038 13.8 0.5 0.096 12.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1664 PF07889.7 EMD69852.1 - 0.048 13.4 0.3 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fip1 PF05182.8 EMD69853.1 - 3e-16 58.4 0.5 5.3e-16 57.6 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif Nop14 PF04147.7 EMD69853.1 - 0.49 8.2 12.2 0.6 7.9 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 EMD69853.1 - 0.59 9.6 4.3 0.79 9.2 3.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.7 EMD69853.1 - 0.63 8.3 9.9 0.87 7.8 6.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LRR_9 PF14580.1 EMD69854.1 - 3.2e-52 176.6 0.0 4.4e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EMD69854.1 - 1.1e-15 56.7 6.0 3.6e-09 36.0 0.1 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMD69854.1 - 9.4e-11 41.3 3.2 2.1e-09 37.0 0.4 3.4 4 1 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EMD69854.1 - 0.00056 19.6 5.6 4.6 7.8 0.0 5.4 6 1 1 7 7 7 2 Leucine rich repeat LRR_1 PF00560.28 EMD69854.1 - 0.003 17.3 9.4 7.9 6.9 0.2 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 EMD69854.1 - 0.21 11.7 9.9 11 6.4 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat Glycos_transf_1 PF00534.15 EMD69855.1 - 1.9e-31 108.7 0.0 9.4e-30 103.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMD69855.1 - 1.1e-08 35.3 0.2 5.2e-08 33.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EMD69855.1 - 3.1e-07 30.2 0.0 2.4e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EMD69855.1 - 2.8e-05 24.3 0.0 0.00036 20.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMD69855.1 - 0.0039 17.4 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MRF_C1 PF13887.1 EMD69855.1 - 0.0081 15.1 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Pkinase PF00069.20 EMD69856.1 - 7.8e-18 64.5 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EMD69856.1 - 1.7e-15 56.1 3.3 3.7e-10 39.2 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 EMD69856.1 - 3.2e-12 45.4 8.2 0.009 16.0 0.1 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 EMD69856.1 - 1.2e-09 38.2 5.0 0.0037 17.4 0.1 3.7 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EMD69856.1 - 0.00058 20.2 6.2 0.067 13.7 0.4 4.7 5 0 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 EMD69856.1 - 0.022 14.6 0.3 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Pkinase_Tyr PF07714.12 EMD69856.1 - 0.03 13.4 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Adaptin_N PF01602.15 EMD69856.1 - 0.037 12.3 0.7 1.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Aa_trans PF01490.13 EMD69858.1 - 3.3e-41 141.1 25.9 3.9e-41 140.8 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMD69858.1 - 2.5e-07 29.8 11.2 2.5e-07 29.8 7.7 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EMD69858.1 - 0.00035 19.3 15.1 0.016 13.8 0.6 2.2 2 0 0 2 2 2 2 Spore germination protein Bac_DNA_binding PF00216.16 EMD69859.1 - 0.14 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial DNA-binding protein zf-CCHC PF00098.18 EMD69861.1 - 0.0081 16.0 1.4 0.012 15.4 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle IL28A PF15177.1 EMD69861.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin-28A 2OG-FeII_Oxy PF03171.15 EMD69871.1 - 4.5e-22 78.2 0.0 8.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMD69871.1 - 2.4e-13 50.6 0.0 4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RNA_pol PF00940.14 EMD69872.1 - 2.5e-161 536.6 0.0 4.4e-161 535.8 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMD69872.1 - 4.6e-68 229.8 5.3 8.6e-68 228.9 3.7 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal TPR_16 PF13432.1 EMD69872.1 - 0.02 15.5 0.1 0.69 10.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_psq PF05225.11 EMD69873.1 - 1.7e-09 37.0 0.1 2.6e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EMD69873.1 - 0.005 16.7 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_24 PF13412.1 EMD69873.1 - 0.0055 16.0 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.8 EMD69873.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.1 EMD69873.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain p450 PF00067.17 EMD69875.1 - 4.1e-62 210.2 0.0 5.1e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chitin_bind_3 PF03067.10 EMD69877.1 - 1.1e-08 35.5 0.6 1.7e-08 34.9 0.4 1.3 1 0 0 1 1 1 1 Chitin binding domain ThiI PF02568.9 EMD69877.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) But2 PF09792.4 EMD69878.1 - 4.3e-26 91.3 0.1 5.2e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AMIN PF11741.3 EMD69878.1 - 0.071 13.0 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AMIN domain Radical_SAM PF04055.16 EMD69879.1 - 4.9e-11 43.0 0.0 7.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMD69879.1 - 3e-06 27.3 0.0 7.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMD69879.1 - 0.0025 17.8 0.1 0.007 16.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Pec_lyase_C PF00544.14 EMD69882.1 - 7.8e-39 133.2 4.1 1.1e-38 132.7 2.5 1.6 1 1 0 1 1 1 1 Pectate lyase WD40 PF00400.27 EMD69883.1 - 2.8e-59 195.0 14.3 1.6e-14 53.1 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 EMD69883.1 - 7.6e-29 100.5 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD69883.1 - 9.1e-23 80.9 9.1 4.2e-20 72.3 0.3 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD69883.1 - 8.5e-05 20.8 4.2 0.077 11.1 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_16 PF13191.1 EMD69883.1 - 0.0013 18.7 0.0 0.0057 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMD69883.1 - 0.011 15.9 0.1 0.04 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMD69883.1 - 0.051 12.4 0.0 0.093 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EMD69883.1 - 0.058 13.1 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain PIF1 PF05970.9 EMD69883.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Arch_ATPase PF01637.13 EMD69883.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Fungal_trans PF04082.13 EMD69885.1 - 2e-12 46.5 0.0 3.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69885.1 - 3.4e-08 33.2 9.5 7.3e-08 32.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EMD69885.1 - 0.0017 17.9 0.8 0.0073 15.9 0.6 2.1 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Sporozoite_P67 PF05642.6 EMD69885.1 - 0.78 7.5 4.2 1.1 7.0 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HTH_Tnp_Tc5 PF03221.11 EMD69887.1 - 1.2e-11 44.2 0.0 2.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD69887.1 - 3.3e-06 26.5 0.2 5.5e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD69887.1 - 0.0017 18.5 0.3 0.0024 17.9 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMD69887.1 - 0.035 14.1 0.1 0.2 11.6 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD69887.1 - 0.06 13.0 0.5 0.36 10.5 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EMD69887.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Transposase Drf_GBD PF06371.8 EMD69887.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Ribosomal_S13_N PF08069.7 EMD69887.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain MFS_1 PF07690.11 EMD69888.1 - 4.7e-06 25.5 10.5 5.2e-06 25.4 7.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM101 PF15111.1 EMD69888.1 - 0.1 11.8 0.8 0.16 11.2 0.2 1.5 1 1 0 1 1 1 0 TMEM101 protein family PLDc_N PF13396.1 EMD69889.1 - 1.2e-12 47.3 5.5 2e-12 46.5 3.8 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.7 EMD69889.1 - 0.027 14.4 0.3 0.027 14.4 0.2 1.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PEN-2 PF10251.4 EMD69889.1 - 0.1 12.8 1.2 0.13 12.5 0.5 1.5 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Tetraspannin PF00335.15 EMD69889.1 - 0.1 11.8 0.6 0.12 11.6 0.4 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF3397 PF11877.3 EMD69889.1 - 0.2 11.6 0.2 0.2 11.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) DUF2207 PF09972.4 EMD69889.1 - 0.23 10.0 1.3 0.23 10.0 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3951 PF13131.1 EMD69889.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) RseC_MucC PF04246.7 EMD69889.1 - 0.89 9.1 3.7 3 7.4 0.2 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF805 PF05656.9 EMD69889.1 - 1.1 9.0 4.2 1.7 8.4 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4064 PF13273.1 EMD69889.1 - 1.4 9.0 6.2 11 6.2 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Ammonium_transp PF00909.16 EMD69891.1 - 7.1e-109 363.9 27.4 8.4e-109 363.6 19.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3482 PF11981.3 EMD69891.1 - 0.47 9.6 2.3 0.78 8.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Rhomboid PF01694.17 EMD69892.1 - 2.7e-12 46.9 12.9 5.2e-12 46.0 8.9 1.4 1 0 0 1 1 1 1 Rhomboid family Autophagy_N PF03986.8 EMD69894.1 - 2 8.1 6.6 1.2 8.9 0.4 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain Methyltransf_33 PF10017.4 EMD69895.1 - 1.1e-36 125.5 0.0 2e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EMD69895.1 - 1.1e-20 74.1 0.6 3.1e-10 39.8 0.1 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EMD69895.1 - 7.9e-05 23.0 0.3 0.00018 21.8 0.2 1.7 1 0 0 1 1 1 1 DinB superfamily PEMT PF04191.8 EMD69897.1 - 1.5e-58 195.4 10.8 2e-35 121.0 1.1 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase Lon_C PF05362.8 EMD69898.1 - 3.1e-64 216.0 0.3 5.9e-64 215.1 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMD69898.1 - 1.8e-25 89.8 0.3 1.8e-25 89.8 0.2 2.2 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMD69898.1 - 8.1e-24 84.3 0.1 8.3e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EMD69898.1 - 2.5e-08 33.4 0.3 4.2e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EMD69898.1 - 5.8e-08 32.5 0.0 2.3e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMD69898.1 - 7.5e-06 26.0 0.3 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMD69898.1 - 1.7e-05 25.5 0.4 9.5e-05 23.2 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_3 PF07726.6 EMD69898.1 - 4.3e-05 23.1 0.0 0.00015 21.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMD69898.1 - 6.1e-05 22.5 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EMD69898.1 - 0.00014 21.0 0.1 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMD69898.1 - 0.00019 20.2 0.2 0.0013 17.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EMD69898.1 - 0.00036 20.6 0.0 0.0051 16.9 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EMD69898.1 - 0.0006 19.7 0.0 0.0025 17.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMD69898.1 - 0.0017 18.2 0.0 0.0049 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMD69898.1 - 0.0018 17.9 0.0 0.0058 16.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EMD69898.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMD69898.1 - 0.0049 16.4 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMD69898.1 - 0.0062 15.6 0.5 0.018 14.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EMD69898.1 - 0.0066 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMD69898.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.9 2 0 0 2 2 1 0 NACHT domain NB-ARC PF00931.17 EMD69898.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EMD69898.1 - 0.016 15.5 0.1 0.065 13.5 0.1 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMD69898.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.6 EMD69898.1 - 0.022 13.4 0.4 3.5 6.2 0.1 2.3 2 0 0 2 2 2 0 PrkA AAA domain DUF258 PF03193.11 EMD69898.1 - 0.029 13.5 0.1 0.086 12.0 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EMD69898.1 - 0.043 13.5 0.0 0.39 10.3 0.0 2.6 1 1 1 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 EMD69898.1 - 0.044 12.9 0.1 0.11 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EMD69898.1 - 0.063 13.6 7.7 0.1 12.8 0.0 3.0 1 1 1 2 2 1 0 AAA domain UPF0079 PF02367.12 EMD69898.1 - 0.066 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EMD69898.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMD69898.1 - 0.14 11.8 1.8 0.21 11.3 0.1 2.3 2 1 0 2 2 1 0 NTPase ABC_tran PF00005.22 EMD69898.1 - 0.92 9.7 3.6 1.2 9.4 0.0 2.8 3 1 0 3 3 2 0 ABC transporter PAT1 PF09770.4 EMD69900.1 - 0.002 16.4 34.3 0.0023 16.2 23.8 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Mem_trans PF03547.13 EMD69900.1 - 0.048 11.9 0.6 0.049 11.9 0.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Mitofilin PF09731.4 EMD69900.1 - 0.074 11.6 14.2 0.097 11.3 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FYVE_2 PF02318.11 EMD69900.1 - 0.076 12.9 30.3 1.1 9.2 1.3 3.4 2 1 1 3 3 3 0 FYVE-type zinc finger DUF4557 PF15101.1 EMD69900.1 - 0.54 10.0 16.3 0.11 12.3 8.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 EMD69900.1 - 0.83 7.2 24.2 1.1 6.8 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.2 EMD69900.1 - 1.5 6.3 13.5 2 5.9 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1675 PF07897.6 EMD69900.1 - 1.9 8.2 13.7 5.1 6.8 9.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PPP4R2 PF09184.6 EMD69900.1 - 2.4 7.6 11.5 3.9 6.9 7.9 1.3 1 0 0 1 1 1 0 PPP4R2 zf-C3HC4 PF00097.20 EMD69900.1 - 7.1 6.3 37.8 3.9 7.2 4.3 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4097 PF13349.1 EMD69901.1 - 0.17 11.4 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DDE_Tnp_ISAZ013 PF07592.6 EMD69902.1 - 0.071 11.8 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain FRQ PF09421.5 EMD69903.1 - 0.03 12.1 1.1 0.039 11.7 0.8 1.0 1 0 0 1 1 1 0 Frequency clock protein MOR2-PAG1_N PF14222.1 EMD69904.1 - 1.3e-207 690.9 0.1 1.2e-206 687.6 0.0 2.1 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EMD69904.1 - 1.3e-85 287.3 2.3 3.6e-85 285.8 1.6 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMD69904.1 - 1.8e-37 128.5 4.3 3.9e-14 51.2 0.1 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.15 EMD69906.1 - 2.6e-57 193.7 0.0 3.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMD69906.1 - 2.6e-33 115.0 1.0 2.6e-33 115.0 0.7 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMD69906.1 - 2e-21 76.6 0.3 1e-20 74.2 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF685 PF05085.7 EMD69906.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF685) Flavodoxin_5 PF12724.2 EMD69906.1 - 0.09 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain RRM_1 PF00076.17 EMD69907.1 - 3.2e-07 29.8 0.2 0.027 14.1 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PC_rep PF01851.17 EMD69908.1 - 8.5e-22 76.1 17.9 1.8e-06 27.8 0.1 8.9 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMD69908.1 - 3e-07 30.6 2.0 0.018 15.3 0.1 4.4 4 1 0 4 4 4 2 HEAT repeats RIO1 PF01163.17 EMD69909.1 - 2.2e-41 141.3 0.0 3.7e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EMD69909.1 - 7.1e-31 106.1 0.0 1.6e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EMD69909.1 - 2.1e-08 34.1 0.2 0.00081 19.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMD69909.1 - 5.6e-06 25.5 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3620 PF12281.3 EMD69910.1 - 0.2 11.3 0.6 0.29 10.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) IF-2B PF01008.12 EMD69911.1 - 1.6e-55 188.1 0.0 1.9e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EMD69911.1 - 0.017 14.7 0.0 0.26 10.9 0.0 2.4 1 1 0 1 1 1 0 DeoR C terminal sensor domain ATP_bind_2 PF03668.10 EMD69912.1 - 7.3e-06 25.2 0.0 1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family Rsc14 PF08586.5 EMD69912.1 - 0.15 12.5 1.2 0.27 11.7 0.4 1.8 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit SLAC1 PF03595.12 EMD69914.1 - 2.7e-75 253.0 42.8 3e-75 252.9 29.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1422 PF07226.6 EMD69914.1 - 2.2 8.0 9.5 0.16 11.6 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1422) DUF1939 PF09154.5 EMD69915.1 - 0.0086 15.9 0.5 0.043 13.7 0.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) ERG2_Sigma1R PF04622.7 EMD69916.1 - 2.2e-90 301.6 0.4 2.5e-90 301.4 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF70 PF01901.11 EMD69916.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF70 DUF2483 PF10656.4 EMD69917.1 - 0.052 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Acetyltransf_7 PF13508.1 EMD69918.1 - 9.3e-09 35.3 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMD69918.1 - 5.9e-08 32.6 0.2 2.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD69918.1 - 8.4e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMD69918.1 - 6.9e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD69918.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein NUDIX PF00293.23 EMD69919.1 - 2.6e-28 98.3 0.0 3.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HMGL-like PF00682.14 EMD69920.1 - 1.1e-69 234.6 0.3 1.9e-69 233.9 0.2 1.4 1 0 0 1 1 1 1 HMGL-like Nuf2 PF03800.9 EMD69921.1 - 2.7e-44 150.7 0.8 8e-44 149.1 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family Thioredoxin PF00085.15 EMD69924.1 - 1.6e-28 98.3 0.1 2.2e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMD69924.1 - 3.7e-06 27.0 0.7 8.9e-05 22.6 0.5 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EMD69924.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMD69924.1 - 0.00021 21.3 0.0 0.0037 17.3 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EMD69924.1 - 0.0097 15.4 0.3 0.19 11.3 0.2 2.1 1 1 1 2 2 2 1 Redoxin Phosducin PF02114.11 EMD69924.1 - 0.014 14.1 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin F-box PF00646.28 EMD69925.1 - 0.00093 18.7 0.2 0.0023 17.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMD69925.1 - 0.035 13.8 0.1 0.12 12.0 0.1 2.0 1 0 0 1 1 1 0 F-box-like DUF2373 PF10180.4 EMD69926.1 - 2.9e-20 71.5 0.0 5e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EMD69927.1 - 2.9e-51 173.4 0.0 3.9e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMD69927.1 - 5.5e-13 47.9 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-RING_2 PF13639.1 EMD69929.1 - 2.6e-08 33.5 7.1 4.2e-08 32.8 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMD69929.1 - 2.4e-05 23.9 8.5 4e-05 23.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMD69929.1 - 0.00043 19.8 5.3 0.00071 19.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMD69929.1 - 0.00074 19.5 3.1 0.0013 18.7 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMD69929.1 - 0.0011 18.9 7.9 0.0019 18.1 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMD69929.1 - 0.0011 18.7 3.1 0.011 15.4 2.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMD69929.1 - 0.0032 17.1 6.9 0.0056 16.3 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EMD69929.1 - 0.074 12.6 5.3 0.45 10.1 3.9 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMD69929.1 - 0.17 11.6 5.0 0.34 10.6 3.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3552 PF12072.3 EMD69929.1 - 4.6 6.4 9.0 0.2 10.8 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Pectate_lyase PF03211.8 EMD69930.1 - 1.5e-79 266.4 7.4 1.8e-79 266.1 5.2 1.0 1 0 0 1 1 1 1 Pectate lyase ICAM_N PF03921.9 EMD69930.1 - 0.8 9.2 4.6 0.93 9.0 2.3 1.8 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF1168 PF06658.7 EMD69934.1 - 2.3e-41 140.6 18.6 3.9e-41 139.8 12.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Vma12 PF11712.3 EMD69934.1 - 0.032 13.9 5.0 0.059 13.0 3.5 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RNase_H2-Ydr279 PF09468.5 EMD69934.1 - 1 8.5 9.6 1.5 7.9 6.7 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) His_Phos_1 PF00300.17 EMD69935.1 - 3.2e-31 108.5 0.0 9.4e-31 107.0 0.0 1.9 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EMD69935.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MEA1 PF06910.6 EMD69935.1 - 0.2 11.3 5.3 0.17 11.5 0.8 2.3 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Fungal_trans_2 PF11951.3 EMD69936.1 - 1.2e-32 112.9 0.4 1.6e-32 112.5 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD69936.1 - 2.7e-07 30.3 8.5 4.9e-07 29.5 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMD69937.1 - 3.7e-24 85.5 0.5 6.1e-15 55.5 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMD69937.1 - 3.3e-19 69.6 0.8 8.4e-18 65.0 0.5 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD69937.1 - 1e-09 38.3 1.8 4.8e-09 36.1 0.0 2.2 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMD69937.1 - 0.009 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding Pyr_redox PF00070.22 EMD69937.1 - 0.011 16.1 0.3 0.033 14.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 EMD69937.1 - 0.034 13.5 0.1 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M24 PF00557.19 EMD69940.1 - 1e-37 129.7 0.3 1.7e-37 129.0 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1803 PF08820.5 EMD69940.1 - 0.072 12.8 0.0 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) ERF PF04404.7 EMD69940.1 - 4.1 6.9 8.6 5.4 6.5 4.0 2.4 3 0 0 3 3 3 0 ERF superfamily C2 PF00168.25 EMD69941.1 - 2.2e-14 53.0 0.0 4.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain FlxA PF14282.1 EMD69941.1 - 0.38 10.7 8.8 0.97 9.4 6.1 1.6 1 0 0 1 1 1 0 FlxA-like protein Sugar_tr PF00083.19 EMD69944.1 - 5.4e-84 282.3 35.9 7.2e-84 281.9 24.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD69944.1 - 2.5e-14 52.7 52.1 5.5e-12 45.0 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M50 PF02163.17 EMD69944.1 - 0.03 13.2 0.0 0.15 10.9 0.0 2.2 1 1 0 1 1 1 0 Peptidase family M50 GTP_EFTU PF00009.22 EMD69945.1 - 2.2e-47 160.9 0.0 3.5e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EMD69945.1 - 4.4e-38 129.5 2.7 6.9e-38 128.8 1.9 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EMD69945.1 - 7.3e-18 64.2 0.0 1.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMD69945.1 - 1.1e-06 28.6 0.0 2.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMD69945.1 - 6.5e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EMD69945.1 - 0.0004 19.7 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 EMD69945.1 - 0.0032 17.2 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EMD69945.1 - 0.011 14.9 0.1 0.033 13.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit HORMA PF02301.13 EMD69946.1 - 5.6e-49 166.4 0.1 5.6e-49 166.4 0.0 1.4 2 0 0 2 2 2 1 HORMA domain Mre11_DNA_bind PF04152.9 EMD69946.1 - 0.33 10.7 2.3 6.6 6.5 0.1 2.6 3 0 0 3 3 3 0 Mre11 DNA-binding presumed domain Glyco_trans_2_3 PF13632.1 EMD69947.1 - 6.3e-48 163.0 5.2 2.8e-47 160.9 3.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMD69947.1 - 3.1e-11 43.5 0.0 1e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMD69947.1 - 3.3e-09 36.6 0.1 4.6e-07 29.6 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMD69947.1 - 4.8e-05 22.7 0.0 0.00021 20.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Lig_chan PF00060.21 EMD69947.1 - 0.77 9.4 3.4 0.71 9.5 0.9 2.0 2 1 0 2 2 2 0 Ligand-gated ion channel Aldedh PF00171.17 EMD69948.1 - 3.2e-112 375.2 1.0 3.9e-112 374.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 EMD69949.1 - 3.4e-33 114.8 29.0 3.4e-33 114.8 20.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69949.1 - 1e-10 40.7 2.5 1e-10 40.7 1.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3638 PF12340.3 EMD69950.1 - 8.4e-101 335.7 0.3 2.4e-100 334.2 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EMD69950.1 - 1.4e-14 52.8 0.1 3.1e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) BTB PF00651.26 EMD69951.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain CbbQ_C PF08406.5 EMD69951.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal Glyco_hydro_16 PF00722.16 EMD69952.1 - 2.8e-14 52.8 0.0 2.8e-14 52.8 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 PAT1 PF09770.4 EMD69952.1 - 4.2 5.4 37.6 5.3 5.1 26.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_1 PF00583.19 EMD69954.1 - 0.00029 20.8 0.1 0.0007 19.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMD69954.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMD69954.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EMD69954.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.11 EMD69955.1 - 7.3e-42 143.3 46.7 7.3e-42 143.3 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69955.1 - 3.1e-10 39.2 34.2 9.2e-09 34.3 23.9 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter PAGK PF15284.1 EMD69955.1 - 0.29 10.9 2.7 0.45 10.3 0.1 2.6 2 0 0 2 2 2 0 Phage-encoded virulence factor NDUF_B8 PF05821.6 EMD69955.1 - 8 6.0 5.7 3.3 7.3 0.2 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) adh_short_C2 PF13561.1 EMD69956.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMD69956.1 - 1.7e-26 93.0 0.5 2.1e-26 92.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMD69956.1 - 5.4e-16 58.7 0.1 7.2e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMD69956.1 - 0.028 13.8 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF885 PF05960.6 EMD69958.1 - 0.0014 17.8 0.8 0.0019 17.4 0.5 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) YopH_N PF09013.5 EMD69958.1 - 0.021 14.4 4.0 0.029 14.0 2.3 1.6 1 1 0 1 1 1 0 YopH, N-terminal Snapin_Pallidin PF14712.1 EMD69958.1 - 0.12 12.6 0.2 0.12 12.6 0.1 3.0 1 1 2 3 3 3 0 Snapin/Pallidin GvpO PF05800.6 EMD69958.1 - 0.19 11.6 1.6 12 5.8 0.3 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO DOG1 PF14144.1 EMD69958.1 - 1 9.4 6.1 15 5.6 1.0 2.6 1 1 1 2 2 2 0 Seed dormancy control NmrA PF05368.8 EMD69959.1 - 2.8e-16 59.4 0.0 4.8e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMD69959.1 - 3.9e-10 40.0 0.0 6e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMD69959.1 - 0.0039 17.4 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EMD69960.1 - 1.2e-48 165.6 48.4 6.6e-48 163.2 33.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMD69960.1 - 1.5e-16 59.7 13.7 1.5e-16 59.7 9.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMD69960.1 - 1.3e-13 50.3 5.5 1.3e-13 50.3 3.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMD69960.1 - 1.4e-08 33.5 29.6 2.3e-05 22.9 2.1 3.5 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EMD69960.1 - 0.00029 20.5 7.5 0.019 14.7 0.7 3.1 3 0 0 3 3 3 2 MFS_1 like family MerC PF03203.9 EMD69960.1 - 0.005 17.2 5.5 0.005 17.2 3.8 4.0 4 2 0 4 4 4 1 MerC mercury resistance protein DUF1911 PF08929.5 EMD69961.1 - 0.59 10.8 5.4 0.99 10.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Aa_trans PF01490.13 EMD69963.1 - 9e-34 116.6 36.9 1.1e-33 116.3 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMD69963.1 - 4.4e-07 28.7 54.8 5.9e-07 28.3 38.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMD69963.1 - 0.0043 15.4 47.4 0.014 13.7 32.9 1.8 1 1 0 1 1 1 1 Amino acid permease NAD_binding_9 PF13454.1 EMD69963.1 - 0.056 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cutinase PF01083.17 EMD69964.1 - 1.8e-26 92.9 0.1 2.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EMD69964.1 - 0.0091 15.7 0.4 0.021 14.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0565 PF10561.4 EMD69964.1 - 0.11 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RhgB_N PF09284.5 EMD69966.1 - 3.4e-62 210.0 0.1 6.1e-62 209.1 0.1 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EMD69966.1 - 2.3e-48 163.9 0.1 1.7e-47 161.1 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMD69966.1 - 2.1e-14 53.3 0.8 2.1e-14 53.3 0.6 2.5 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMD69966.1 - 0.00037 20.5 0.2 0.0012 18.8 0.2 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain WW PF00397.21 EMD69967.1 - 1.8e-07 30.8 6.0 1.8e-07 30.8 4.2 2.0 2 0 0 2 2 2 1 WW domain F-box-like_2 PF13013.1 EMD69968.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain OTU PF02338.14 EMD69972.1 - 5.5e-14 52.8 0.3 5.5e-14 52.8 0.2 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMD69972.1 - 0.00032 20.1 0.0 0.76 9.0 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain PepSY_2 PF13670.1 EMD69972.1 - 1.3 9.0 6.3 2.5 8.0 0.2 3.2 2 1 1 3 3 3 0 Peptidase propeptide and YPEB domain MC1 PF05854.6 EMD69972.1 - 1.6 8.7 7.5 0.16 11.9 0.6 2.4 1 1 1 2 2 2 0 Non-histone chromosomal protein MC1 Neur_chan_memb PF02932.11 EMD69972.1 - 3.4 7.5 8.6 5 6.9 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2031 PF09592.5 EMD69972.1 - 3.9 6.5 8.8 6 5.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) TPMT PF05724.6 EMD69973.1 - 9.5e-27 93.8 0.0 6.7e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 EMD69973.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMD69973.1 - 3.6e-06 26.8 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD69973.1 - 8.2e-05 23.1 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD69973.1 - 0.011 16.1 0.0 0.035 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMD69973.1 - 0.027 14.9 0.0 0.067 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMD69973.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EMD69973.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein MFS_1 PF07690.11 EMD69974.1 - 6.5e-45 153.3 30.6 6.5e-45 153.3 21.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD69974.1 - 6.8e-09 34.8 17.1 6.8e-09 34.8 11.9 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EMD69974.1 - 0.0015 16.7 4.8 1.1 7.2 0.5 3.4 3 1 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family SPC25 PF06703.6 EMD69974.1 - 0.1 12.1 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ABC_tran PF00005.22 EMD69975.1 - 9.7e-70 233.2 0.1 2.4e-34 118.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMD69975.1 - 3.5e-68 229.9 36.7 3.2e-34 118.6 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMD69975.1 - 2.1e-14 53.3 2.4 9.4e-05 21.7 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD69975.1 - 1.8e-12 47.8 0.0 0.066 13.1 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 EMD69975.1 - 4.7e-11 43.0 2.2 2e-05 24.6 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD69975.1 - 2.6e-09 36.4 0.1 0.00028 20.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EMD69975.1 - 7.8e-09 34.6 2.1 0.0027 16.3 0.0 3.3 4 0 0 4 4 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EMD69975.1 - 1.4e-07 30.8 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMD69975.1 - 1.4e-06 28.4 2.3 0.19 11.8 0.1 4.4 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EMD69975.1 - 1.5e-06 29.0 0.0 0.049 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMD69975.1 - 6.2e-06 25.7 1.9 0.16 11.3 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EMD69975.1 - 2.2e-05 24.3 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMD69975.1 - 3.8e-05 23.4 0.2 0.3 10.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EMD69975.1 - 3.8e-05 22.5 0.0 0.055 12.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.1 EMD69975.1 - 8.4e-05 22.8 0.0 2.8 8.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EMD69975.1 - 0.00039 20.6 0.0 4 7.6 0.0 4.7 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EMD69975.1 - 0.00061 19.6 6.5 0.28 11.1 0.1 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMD69975.1 - 0.0014 18.9 0.0 0.89 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EMD69975.1 - 0.0021 17.1 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EMD69975.1 - 0.0024 17.4 4.7 2.1 7.8 0.4 4.1 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EMD69975.1 - 0.0029 16.7 0.3 0.82 8.7 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin DUF3676 PF12429.3 EMD69975.1 - 0.0038 16.8 0.4 0.0077 15.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3676) SRP54 PF00448.17 EMD69975.1 - 0.0056 16.1 0.2 2.2 7.6 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EMD69975.1 - 0.0078 16.1 0.0 4.4 7.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.12 EMD69975.1 - 0.011 15.5 0.6 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 EMD69975.1 - 0.013 15.5 0.0 0.37 10.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EMD69975.1 - 0.014 15.0 0.5 5.2 6.7 0.1 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EMD69975.1 - 0.015 15.2 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 EMD69975.1 - 0.018 14.5 0.1 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EMD69975.1 - 0.019 15.1 0.0 2.6 8.2 0.0 3.1 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 EMD69975.1 - 0.025 13.2 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EMD69975.1 - 0.036 12.9 0.1 2 7.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 EMD69975.1 - 0.044 13.4 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EMD69975.1 - 0.062 12.2 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 EMD69975.1 - 0.08 13.4 0.3 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein ATP-synt_ab PF00006.20 EMD69975.1 - 0.084 12.3 0.7 0.7 9.3 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EMD69975.1 - 0.17 11.2 3.5 16 4.7 0.1 4.1 4 1 0 5 5 5 0 AAA-like domain NACHT PF05729.7 EMD69975.1 - 0.18 11.4 0.3 15 5.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MFS_1 PF07690.11 EMD69976.1 - 3e-32 111.7 26.6 3e-32 111.7 18.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MatE PF01554.13 EMD69977.1 - 6.4e-57 191.7 26.8 5.1e-31 107.4 6.0 2.4 2 0 0 2 2 2 2 MatE Pex2_Pex12 PF04757.9 EMD69977.1 - 7.9e-56 189.0 1.4 7.9e-56 189.0 1.0 1.7 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EMD69977.1 - 7.5e-05 22.6 0.8 0.00014 21.8 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMD69977.1 - 0.00058 19.6 0.6 0.001 18.8 0.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMD69977.1 - 0.011 15.3 0.3 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMD69977.1 - 0.018 14.8 0.6 0.033 14.0 0.4 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EMD69977.1 - 0.25 11.0 0.2 0.42 10.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M28 PF04389.12 EMD69978.1 - 1.4e-35 122.6 0.0 2.2e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PQ-loop PF04193.9 EMD69978.1 - 3.4e-23 80.9 16.8 2.1e-12 46.3 0.9 3.2 3 0 0 3 3 3 2 PQ loop repeat PA PF02225.17 EMD69978.1 - 3.9e-12 45.7 0.1 8.8e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EMD69978.1 - 0.015 14.1 0.0 0.065 11.9 0.0 1.7 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase DctQ PF04290.7 EMD69978.1 - 1.2 8.8 15.1 8.2 6.1 6.6 3.1 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Chlamy_scaf PF09675.5 EMD69981.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Spc97_Spc98 PF04130.8 EMD69982.1 - 6.5e-74 249.1 3.1 6.5e-74 249.1 2.2 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family Cytochrom_B559a PF00284.15 EMD69983.1 - 0.038 13.5 0.7 5 6.7 0.0 3.2 2 1 1 3 3 3 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit F1F0-ATPsyn_F PF10791.4 EMD69985.1 - 7e-41 138.3 0.2 7.9e-41 138.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.7 EMD69986.1 - 1.1e-34 118.3 1.1 1.7e-34 117.6 0.7 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region HrpA_pilin PF09589.5 EMD69987.1 - 2 8.8 7.5 2.5 8.5 5.2 1.1 1 0 0 1 1 1 0 HrpA pilus formation protein Lipase_GDSL_2 PF13472.1 EMD69988.1 - 7.5e-13 48.9 0.2 1.2e-12 48.3 0.1 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMD69988.1 - 6.5e-09 35.9 0.0 9.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GAGA_bind PF06217.7 EMD69989.1 - 3.6 7.4 7.5 26 4.6 5.2 2.0 1 1 0 1 1 1 0 GAGA binding protein-like family Pyridox_oxase_2 PF12766.2 EMD69992.1 - 6.1e-26 90.6 0.0 1.5e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CDC27 PF09507.5 EMD69993.1 - 1.4e-83 281.5 31.6 2.3e-83 280.8 21.9 1.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 TFCD_C PF12612.3 EMD69994.1 - 5.6e-27 94.4 3.1 8.8e-26 90.5 2.2 2.7 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EMD69994.1 - 0.0022 17.9 11.6 2.4 8.4 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EMD69994.1 - 0.0084 16.3 6.7 0.09 13.0 0.0 5.3 6 0 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EMD69994.1 - 0.023 15.0 0.0 0.16 12.3 0.0 2.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMD69994.1 - 0.35 11.4 0.0 0.35 11.4 0.0 6.7 8 1 0 8 8 8 0 HEAT-like repeat DAO PF01266.19 EMD69995.1 - 7.7e-29 100.7 0.4 8.8e-29 100.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMD69995.1 - 0.019 15.3 0.1 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMD69995.1 - 0.043 13.8 0.2 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMD69995.1 - 0.045 12.8 2.3 0.053 12.6 0.1 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 EMD69995.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding OTU PF02338.14 EMD69996.1 - 2.9e-17 63.3 1.3 1e-16 61.6 0.9 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMD69996.1 - 3.5e-05 23.2 0.6 0.032 13.5 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain TRAPPC-Trs85 PF12739.2 EMD69997.1 - 1.3e-119 399.6 2.6 5.5e-119 397.5 2.4 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.12 EMD69997.1 - 0.12 12.3 1.1 2.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2454 PF10521.4 EMD69998.1 - 2e-52 177.9 1.0 3.3e-52 177.2 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EMD69998.1 - 4e-20 72.2 0.6 3.8e-19 69.1 0.4 2.3 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EMD69998.1 - 9.1e-08 31.5 0.1 3e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EMD69998.1 - 4.4e-05 23.3 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF1218 PF06749.7 EMD69999.1 - 0.078 13.4 9.2 2.1 8.8 4.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Spore_YabQ PF09578.5 EMD69999.1 - 0.22 11.4 4.4 2.9 7.9 0.3 2.7 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF4013 PF13197.1 EMD69999.1 - 0.59 9.4 5.3 1.4 8.2 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) Mito_fiss_reg PF05308.6 EMD69999.1 - 0.8 9.0 3.8 1.3 8.3 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3357 PF11837.3 EMD69999.1 - 1.7 8.5 4.5 3.6 7.4 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Npa1 PF11707.3 EMD70000.1 - 7.2e-89 298.0 0.0 2.4e-88 296.3 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal HEAT PF02985.17 EMD70000.1 - 0.032 14.2 0.1 13 6.1 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat HET PF06985.6 EMD70002.1 - 4.9e-20 72.1 6.8 1.4e-17 64.1 4.6 3.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EMD70002.1 - 2.9e-10 39.4 0.0 5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EMD70002.1 - 3.1e-06 27.3 0.0 1e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD70002.1 - 1e-05 25.6 0.1 2.4e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMD70002.1 - 0.0092 15.3 0.0 0.041 13.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EMD70002.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EMD70002.1 - 0.013 15.2 0.0 0.05 13.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 EMD70002.1 - 0.022 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_35 PF14516.1 EMD70002.1 - 0.044 12.4 0.0 0.081 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TPR_10 PF13374.1 EMD70003.1 - 1.7e-38 129.4 0.0 2.5e-11 43.0 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMD70003.1 - 4.7e-29 100.1 0.0 1.5e-11 44.0 0.0 3.6 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMD70003.1 - 6.8e-09 34.9 0.0 0.06 13.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMD70003.1 - 8.4e-09 34.6 0.0 0.0084 15.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMD70003.1 - 9.5e-09 34.7 0.0 1.8e-05 24.2 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 EMD70003.1 - 7.6e-07 29.6 0.0 0.00025 21.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMD70003.1 - 5.8e-06 26.4 0.3 0.73 10.4 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMD70003.1 - 1e-05 25.3 0.0 3.5 8.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMD70003.1 - 9.5e-05 22.6 0.2 0.25 11.7 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMD70003.1 - 0.00014 21.9 0.0 0.015 15.4 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EMD70003.1 - 0.00075 19.6 0.0 6.3 7.5 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMD70003.1 - 0.0021 18.5 0.0 4.7 8.1 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMD70003.1 - 0.0026 17.4 0.4 3.5 7.6 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EMD70003.1 - 0.016 14.9 0.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1897 PF09005.5 EMD70003.1 - 0.063 12.7 0.8 8.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) SPATIAL PF15256.1 EMD70003.1 - 0.12 12.3 0.3 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 SPATIAL Opiods_neuropep PF01160.13 EMD70003.1 - 0.13 12.0 0.7 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide Glyco_hydro_72 PF03198.9 EMD70004.1 - 5.5e-111 370.5 2.6 5.5e-111 370.5 1.8 1.4 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 EMD70004.1 - 6.5e-20 71.4 8.9 6.5e-20 71.4 6.2 2.0 2 0 0 2 2 2 1 X8 domain bZIP_1 PF00170.16 EMD70005.1 - 1.7e-05 24.6 9.2 3.4e-05 23.7 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF1875 PF08961.5 EMD70005.1 - 0.0007 18.9 0.5 0.001 18.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) TMF_DNA_bd PF12329.3 EMD70005.1 - 0.016 14.9 1.2 0.028 14.2 0.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EMD70005.1 - 0.079 12.4 1.0 0.16 11.5 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 EMD70005.1 - 0.085 13.1 0.3 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pex14_N PF04695.8 EMD70005.1 - 0.11 12.5 1.9 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region bZIP_2 PF07716.10 EMD70005.1 - 0.13 12.1 10.5 0.22 11.3 7.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Prominin PF05478.6 EMD70005.1 - 0.3 8.5 0.5 0.38 8.2 0.3 1.0 1 0 0 1 1 1 0 Prominin Oligomerisation PF02410.10 EMD70006.1 - 1.1e-06 28.5 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 2 Oligomerisation domain NMD3 PF04981.8 EMD70007.1 - 3.6e-72 242.2 1.5 6.6e-72 241.4 1.0 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 EMD70007.1 - 0.053 13.3 6.2 1.9 8.4 0.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 EMD70007.1 - 2.1 8.0 4.4 16 5.1 0.1 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family CENP-L PF13092.1 EMD70009.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 GMC_oxred_N PF00732.14 EMD70010.1 - 1.1e-49 169.1 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMD70010.1 - 1.3e-41 142.2 0.0 2e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMD70010.1 - 9.2e-07 28.0 0.3 9.8e-06 24.7 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMD70010.1 - 0.0021 17.0 0.1 0.0041 16.0 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HHH PF00633.18 EMD70010.1 - 0.014 15.1 0.2 1.2 9.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif NAD_binding_8 PF13450.1 EMD70010.1 - 0.015 15.2 0.2 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMD70010.1 - 0.061 13.0 0.4 5.3 6.7 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMD70010.1 - 0.11 12.4 0.1 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD70010.1 - 0.11 11.0 0.1 0.19 10.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase IncA PF04156.9 EMD70011.1 - 0.019 14.5 0.4 0.025 14.1 0.3 1.3 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 EMD70011.1 - 0.03 14.6 0.3 0.045 14.0 0.2 1.4 1 1 0 1 1 1 0 Striatin family DUF2205 PF10224.4 EMD70011.1 - 0.03 13.8 0.5 0.059 12.9 0.3 1.5 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4559 PF15112.1 EMD70011.1 - 0.046 12.8 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3654 PF12376.3 EMD70011.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Shugoshin_N PF07558.6 EMD70011.1 - 0.1 12.2 0.2 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Filament PF00038.16 EMD70011.1 - 0.11 11.8 4.2 3.1 7.1 1.7 2.0 1 1 1 2 2 2 0 Intermediate filament protein CENP-Q PF13094.1 EMD70011.1 - 0.45 10.5 4.3 0.47 10.4 2.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_CLD_2 PF14197.1 EMD70011.1 - 0.81 9.6 5.8 0.5 10.3 2.1 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Glyco_hydro_30 PF02055.11 EMD70012.1 - 3.2e-17 61.9 0.1 1e-16 60.2 0.1 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EMD70012.1 - 0.0046 15.9 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 HET PF06985.6 EMD70013.1 - 3.1e-35 121.3 0.3 5.2e-35 120.6 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SurE PF01975.12 EMD70015.1 - 2e-37 128.4 0.0 3e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Clr2 PF10383.4 EMD70016.1 - 2.7e-24 85.7 0.0 5e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.18 EMD70017.1 - 2e-61 207.3 0.0 1.1e-60 204.9 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD70017.1 - 2.2e-10 40.2 0.1 8.5e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMD70017.1 - 9.3e-06 24.6 0.0 3.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EMD70017.1 - 0.0049 16.3 0.0 0.038 13.4 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EMD70017.1 - 0.019 14.6 17.1 0.019 14.6 5.5 2.8 2 1 1 3 3 3 0 PHD-finger C1_1 PF00130.17 EMD70017.1 - 0.14 11.8 18.2 0.36 10.5 2.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EMD70017.1 - 0.25 10.5 9.2 0.95 8.7 0.8 2.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.1 EMD70017.1 - 5.1 7.0 18.3 1.8 8.4 3.2 2.6 2 0 0 2 2 2 0 Ring finger domain Thioredoxin PF00085.15 EMD70018.1 - 1.1e-09 37.9 0.0 1.3e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EMD70018.1 - 0.0024 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMD70018.1 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EMD70018.1 - 0.011 15.8 0.0 0.045 13.8 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.16 EMD70018.1 - 0.012 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.1 EMD70018.1 - 0.035 14.3 0.0 0.55 10.4 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 EMD70018.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin Peptidase_C48 PF02902.14 EMD70019.1 - 0.00098 18.8 0.1 0.46 10.0 0.0 2.9 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Stork_head PF10264.4 EMD70019.1 - 0.14 12.3 0.1 57 3.9 0.0 4.1 4 0 0 4 4 4 0 Winged helix Storkhead-box1 domain UBA PF00627.26 EMD70020.1 - 0.14 12.0 0.2 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain bZIP_1 PF00170.16 EMD70020.1 - 0.2 11.6 8.6 0.11 12.4 4.4 1.7 1 1 1 2 2 2 0 bZIP transcription factor Colicin_V PF02674.11 EMD70021.1 - 1.9 8.3 15.2 0.13 12.0 2.7 2.4 2 0 0 2 2 2 0 Colicin V production protein His_Phos_1 PF00300.17 EMD70022.1 - 1.3e-21 77.3 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNase_H2_suC PF08615.6 EMD70023.1 - 1.1e-25 90.0 0.0 1.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EMD70024.1 - 5.1e-68 229.1 0.0 1.2e-67 227.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMD70024.1 - 3.2e-08 33.4 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMD70024.1 - 3.6e-08 33.9 0.0 6.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD70024.1 - 1.1e-07 32.1 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD70024.1 - 1.6e-05 24.5 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMD70024.1 - 0.00033 21.0 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMD70024.1 - 0.00065 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMD70024.1 - 0.0016 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EMD70024.1 - 0.0032 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4165 PF13752.1 EMD70026.1 - 0.094 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) NUC153 PF08159.7 EMD70027.1 - 1.3e-13 50.2 0.3 1.3e-13 50.2 0.2 4.3 4 0 0 4 4 4 2 NUC153 domain DHquinase_II PF01220.14 EMD70029.1 - 4.2e-62 207.5 0.1 4.8e-62 207.3 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.20 EMD70030.1 - 1.1e-80 270.8 0.0 1.3e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 EMD70031.1 - 1.1e-23 83.1 0.0 2.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMD70031.1 - 9.3e-15 54.9 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1143 PF06608.6 EMD70031.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) YoaP PF14268.1 EMD70031.1 - 0.13 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 YoaP-like Sugar_tr PF00083.19 EMD70032.1 - 5.4e-130 433.9 22.2 6.2e-130 433.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD70032.1 - 1.8e-21 76.2 39.0 9.8e-21 73.8 25.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily AP_endonuc_2 PF01261.19 EMD70033.1 - 2.7e-30 105.2 0.0 1.2e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel ATP-grasp PF02222.17 EMD70033.1 - 0.096 12.0 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Fungal_trans PF04082.13 EMD70034.1 - 3.6e-09 35.8 1.2 1.1e-08 34.2 0.9 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMD70034.1 - 1.9e-07 30.8 13.4 3.2e-07 30.1 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EMD70035.1 - 3.2e-43 147.9 0.0 6.4e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EMD70035.1 - 1.1e-17 63.7 0.0 2.9e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EMD70035.1 - 4.5e-15 55.8 0.0 8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EMD70035.1 - 2e-11 44.1 0.7 3.9e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMD70035.1 - 0.018 14.8 0.2 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 ThiF family AAA_17 PF13207.1 EMD70035.1 - 0.027 15.2 0.0 0.059 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMD70035.1 - 0.076 12.7 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CM_2 PF01817.16 EMD70036.1 - 3.2e-08 33.5 0.1 0.00019 21.4 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 EMD70037.1 - 3.1e-38 128.3 8.9 2.1e-09 36.9 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMD70037.1 - 1.3e-05 23.5 12.1 0.073 11.2 0.6 4.8 2 2 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMD70037.1 - 0.00025 20.8 0.0 0.017 14.8 0.0 3.3 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region APG6 PF04111.7 EMD70037.1 - 0.089 11.8 0.9 0.14 11.1 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HTH_psq PF05225.11 EMD70038.1 - 8.8e-07 28.3 0.4 1.2e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EMD70038.1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EMD70038.1 - 0.044 13.7 0.0 0.058 13.3 0.0 1.3 1 1 0 1 1 1 0 Transposase HTH_23 PF13384.1 EMD70038.1 - 0.059 13.0 0.0 0.092 12.4 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EMD70038.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.16 EMD70038.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_3 PF01381.17 EMD70038.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_36 PF13730.1 EMD70038.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pyr_redox_2 PF07992.9 EMD70039.1 - 1.1e-19 71.0 0.0 1.8e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMD70039.1 - 1.7e-12 47.5 0.0 1.3e-09 38.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EMD70039.1 - 1.9e-06 26.7 0.3 5.7e-06 25.2 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMD70039.1 - 1.2e-05 24.7 1.1 4.5e-05 22.9 0.4 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EMD70039.1 - 6.2e-05 22.1 0.7 6.2e-05 22.1 0.5 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EMD70039.1 - 0.00012 22.1 0.1 0.00029 20.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 EMD70039.1 - 0.15 12.1 0.0 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 EMD70040.1 - 4.2e-07 29.5 0.1 1.2e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD70040.1 - 3.2e-06 26.6 0.3 7.9e-06 25.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain DUF1772 PF08592.6 EMD70041.1 - 1.2e-14 54.2 0.8 3.6e-11 42.9 0.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.11 EMD70042.1 - 4.6e-32 111.1 40.3 4.4e-23 81.5 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD70042.1 - 1.6e-06 26.8 23.8 1.4e-05 23.6 5.7 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Tetraspannin PF00335.15 EMD70042.1 - 0.012 14.9 1.5 0.012 14.9 1.0 2.9 2 1 1 3 3 3 0 Tetraspanin family ALG3 PF05208.8 EMD70043.1 - 7.6e-132 439.9 13.8 8.8e-132 439.7 9.6 1.0 1 0 0 1 1 1 1 ALG3 protein HTH_Tnp_Tc5 PF03221.11 EMD70044.1 - 2.1e-11 43.4 0.0 4.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EMD70044.1 - 6.1e-06 25.6 0.2 1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EMD70044.1 - 0.0045 17.1 1.3 0.0077 16.3 0.4 1.7 1 1 1 2 2 2 1 Winged helix-turn helix DUF2500 PF10694.4 EMD70044.1 - 0.038 14.0 0.7 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Drf_GBD PF06371.8 EMD70044.1 - 0.041 13.2 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_28 PF13518.1 EMD70044.1 - 0.07 13.1 0.1 0.36 10.8 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EMD70044.1 - 0.085 12.5 0.2 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain MOZ_SAS PF01853.13 EMD70046.1 - 5.2e-88 293.2 0.1 7.9e-88 292.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EMD70046.1 - 1.5e-24 85.4 0.4 3e-24 84.4 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EMD70046.1 - 0.031 13.6 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) RNase_T PF00929.19 EMD70047.1 - 2.5e-27 96.1 0.0 3.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Aldo_ket_red PF00248.16 EMD70048.1 - 2.5e-62 210.3 0.0 2.8e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-MYND PF01753.13 EMD70049.1 - 4.4e-10 39.2 11.8 6.8e-10 38.6 8.2 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EMD70049.1 - 0.22 11.3 4.3 0.43 10.4 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Fer4_2 PF12797.2 EMD70049.1 - 0.32 11.0 5.8 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain HypA PF01155.14 EMD70049.1 - 1.8 8.2 4.0 3.2 7.4 2.8 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GATA PF00320.22 EMD70050.1 - 9.8e-32 108.0 15.6 6.7e-17 60.5 1.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMD70050.1 - 4e-06 26.0 3.0 0.005 16.1 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 EMD70050.1 - 2.5e-05 23.6 3.1 0.065 12.7 0.2 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EMD70050.1 - 0.0012 18.7 1.9 0.86 9.6 0.0 2.7 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EMD70050.1 - 0.0018 17.9 7.4 0.0087 15.6 0.1 2.8 3 0 0 3 3 3 2 Putative transposase DNA-binding domain DZR PF12773.2 EMD70050.1 - 0.03 14.1 10.5 0.52 10.1 0.1 3.3 3 0 0 3 3 3 0 Double zinc ribbon ArfGap PF01412.13 EMD70050.1 - 0.036 13.8 6.1 2.7 7.8 0.0 3.2 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.7 EMD70050.1 - 0.046 13.4 3.2 1.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Elf1 PF05129.8 EMD70050.1 - 0.089 12.4 0.9 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 EMD70050.1 - 0.099 12.2 8.0 0.057 12.9 0.5 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-CHY PF05495.7 EMD70050.1 - 0.18 11.9 2.4 4.1 7.6 0.2 2.9 2 0 0 2 2 2 0 CHY zinc finger eIF-5_eIF-2B PF01873.12 EMD70050.1 - 0.2 11.3 5.3 2.7 7.6 0.6 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FYVE PF01363.16 EMD70050.1 - 1 9.2 6.0 6.4 6.7 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger FAM163 PF15069.1 EMD70050.1 - 2.6 8.6 11.2 4.6 7.8 3.0 3.2 2 2 1 3 3 3 0 FAM163 family COPI_assoc PF08507.5 EMD70051.1 - 2.3e-42 143.9 4.7 2.4e-42 143.8 3.2 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3096 PF11295.3 EMD70051.1 - 0.014 14.9 6.8 0.27 10.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) DUF2636 PF11120.3 EMD70051.1 - 1.3 8.6 3.5 3 7.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) YtpI PF14007.1 EMD70051.1 - 1.5 8.7 10.1 0.075 12.9 2.6 1.9 1 1 1 2 2 2 0 YtpI-like protein DUF2964 PF11177.3 EMD70051.1 - 6.9 6.6 6.9 1.8 8.5 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) Adeno_E3_14_5 PF04834.7 EMD70053.1 - 0.26 11.7 0.9 0.79 10.1 0.4 2.0 1 1 0 1 1 1 0 Early E3 14.5 kDa protein zf-C2H2 PF00096.21 EMD70054.1 - 0.0017 18.6 14.0 0.074 13.4 0.2 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD70054.1 - 0.041 14.2 14.3 0.12 12.7 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD70054.1 - 0.061 13.4 1.9 0.25 11.5 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CAP_assoc_N PF14504.1 EMD70055.1 - 0.036 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 CAP-associated N-terminal RNA_pol_I_TF PF04090.7 EMD70055.1 - 0.12 11.6 0.0 0.6 9.3 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Ndc1_Nup PF09531.5 EMD70055.1 - 1.4 7.2 5.4 1.8 6.8 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ras PF00071.17 EMD70058.1 - 8e-59 197.6 0.2 9.5e-59 197.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMD70058.1 - 3.1e-19 69.6 0.0 4.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMD70058.1 - 6.2e-09 35.3 0.0 7e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMD70058.1 - 9.2e-08 31.7 0.2 5e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EMD70058.1 - 0.00016 20.9 0.0 0.00025 20.3 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EMD70058.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase phiKZ_IP PF12699.2 EMD70058.1 - 0.041 12.8 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins ATP_bind_1 PF03029.12 EMD70058.1 - 0.054 13.0 1.9 0.58 9.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EMD70058.1 - 0.054 12.6 0.1 0.2 10.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EMD70058.1 - 0.1 11.9 0.7 0.68 9.3 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein MoCF_biosynth PF00994.19 EMD70059.1 - 6.2e-37 126.1 0.0 9.6e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 EMD70060.1 - 4.4e-09 36.2 0.0 5.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1344 PF07076.6 EMD70060.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF4385 PF14328.1 EMD70061.1 - 1.3e-56 190.5 3.1 1.7e-56 190.1 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Metallophos PF00149.23 EMD70063.1 - 7.8e-38 129.8 0.2 8.5e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase MFS_1 PF07690.11 EMD70064.1 - 4.2e-31 107.9 37.6 4.2e-31 107.9 26.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.16 EMD70065.1 - 7.4e-41 140.1 13.5 5.5e-39 134.0 9.3 2.6 1 1 0 1 1 1 1 POT family Ank PF00023.25 EMD70066.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EMD70066.1 - 0.0037 17.4 0.0 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMD70066.1 - 0.021 15.1 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMD70066.1 - 0.042 14.3 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 EMD70067.1 - 1.2e-17 64.4 0.0 1.3e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 EMD70069.1 - 8.4e-17 61.8 1.0 1.9e-16 60.6 0.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD70069.1 - 2e-12 47.0 0.2 3.5e-12 46.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMD70069.1 - 9.4e-05 22.1 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMD70069.1 - 0.49 9.5 1.8 0.5 9.5 0.4 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aft1_HRA PF11786.3 EMD70070.1 - 1.5e-28 98.8 10.3 1.5e-28 98.8 7.1 2.9 1 1 1 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EMD70070.1 - 1e-15 58.4 16.2 1e-15 58.4 11.3 4.0 3 2 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.3 EMD70070.1 - 8.8e-15 54.9 7.0 8.8e-15 54.9 4.8 4.4 3 1 2 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EMD70070.1 - 2.9e-13 49.5 5.4 5.1e-13 48.7 3.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMD70070.1 - 8.7e-06 25.4 5.4 1.7e-05 24.5 3.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMD70070.1 - 0.0029 17.8 4.3 0.0091 16.2 3.0 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor Transthyretin PF00576.16 EMD70072.1 - 3.4e-28 97.7 0.2 1e-27 96.2 0.1 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.11 EMD70072.1 - 0.0052 16.6 0.2 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Opy2 PF09463.5 EMD70073.1 - 0.0035 17.3 16.2 0.0061 16.6 11.3 1.4 1 0 0 1 1 1 1 Opy2 protein GCIP PF13324.1 EMD70073.1 - 0.031 13.5 0.4 0.031 13.5 0.3 1.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Ras PF00071.17 EMD70075.1 - 2.8e-17 62.5 0.0 7.8e-17 61.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMD70075.1 - 1.3e-07 32.1 0.0 3.9e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EMD70075.1 - 0.036 13.5 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.18 EMD70075.1 - 0.044 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family G-alpha PF00503.15 EMD70075.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_M14 PF00246.19 EMD70076.1 - 2.5e-42 145.4 1.3 3.6e-42 144.9 0.9 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase HET PF06985.6 EMD70077.1 - 5.4e-25 88.1 0.0 1e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pribosyl_synth PF14572.1 EMD70078.1 - 2.8e-40 138.0 2.5 2.1e-35 122.1 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMD70078.1 - 3.3e-34 117.0 0.0 1.4e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMD70078.1 - 8e-12 44.9 0.3 2.2e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMD70078.1 - 0.0067 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ICL PF00463.16 EMD70080.1 - 2.1e-284 943.5 3.0 2.4e-284 943.4 2.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMD70080.1 - 3.4e-12 46.0 0.3 5.7e-11 42.0 0.1 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fae PF08714.6 EMD70080.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) DUF1365 PF07103.6 EMD70081.1 - 6.9e-31 107.2 0.0 5.6e-30 104.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) RasGAP PF00616.14 EMD70083.1 - 3.6e-45 154.0 0.0 3.6e-45 154.0 0.0 2.7 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMD70083.1 - 0.00011 21.9 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Nucleo_P87 PF07267.6 EMD70083.1 - 5.1 5.6 6.6 9.1 4.8 4.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pro_isomerase PF00160.16 EMD70084.1 - 5.2e-45 153.4 0.7 7.9e-45 152.8 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EMD70084.1 - 3.9e-14 52.0 9.4 8.2e-09 34.9 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.1 EMD70084.1 - 3.9e-05 23.5 4.9 0.00017 21.4 2.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMD70084.1 - 4.3e-05 23.1 13.8 0.0069 16.2 1.9 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMD70084.1 - 6.7e-05 22.3 14.0 0.039 13.5 1.4 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMD70084.1 - 0.14 12.9 4.2 0.7 10.6 1.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EMD70084.1 - 0.22 11.4 5.1 3.2 7.7 1.2 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 EMD70084.1 - 0.26 12.0 5.4 5.2 7.8 3.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMD70084.1 - 1.3 9.0 15.8 0.091 12.5 1.6 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat IFRD PF05004.8 EMD70085.1 - 1.5e-34 119.4 6.1 2.2e-34 118.9 4.2 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EMD70085.1 - 0.028 14.8 0.5 13 6.4 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat GlutR_N PF05201.10 EMD70085.1 - 0.068 12.7 3.0 0.046 13.3 0.3 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain zf-C2H2 PF00096.21 EMD70087.1 - 5.3e-05 23.3 8.8 0.027 14.7 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD70087.1 - 5.9e-05 23.1 10.2 0.051 13.9 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD70087.1 - 1.8 9.0 7.4 1.1 9.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Not3 PF04065.10 EMD70088.1 - 2.3e-99 331.3 32.4 3.7e-99 330.7 22.4 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EMD70088.1 - 9.1e-44 148.5 11.4 2.7e-43 147.0 7.9 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EMD70088.1 - 0.0072 15.8 3.0 0.017 14.6 2.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CorA PF01544.13 EMD70088.1 - 0.12 11.4 6.4 0.052 12.5 2.4 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1192 PF06698.6 EMD70088.1 - 0.21 11.4 4.5 0.63 9.8 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CHD5 PF04420.9 EMD70088.1 - 0.97 9.0 5.2 5 6.7 0.4 2.5 2 0 0 2 2 2 0 CHD5-like protein Syntaxin PF00804.20 EMD70088.1 - 1.2 9.2 21.1 0.28 11.3 3.2 3.3 2 1 1 3 3 3 0 Syntaxin DUF948 PF06103.6 EMD70088.1 - 6.3 6.7 5.6 2.6 7.9 1.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tyr_Deacylase PF02580.11 EMD70089.1 - 8e-47 158.8 0.0 9.4e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2914 PF11141.3 EMD70089.1 - 0.039 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) ABC_membrane PF00664.18 EMD70090.1 - 1.1e-85 287.3 41.1 3.9e-46 157.6 13.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMD70090.1 - 2e-68 228.9 0.0 7.1e-33 113.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMD70090.1 - 2.7e-14 52.9 6.4 1.5e-05 24.3 1.8 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMD70090.1 - 6.8e-14 52.5 0.0 0.0042 17.0 0.0 4.4 2 2 0 3 3 3 3 AAA domain AAA_17 PF13207.1 EMD70090.1 - 4.4e-10 40.4 0.0 0.00044 21.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMD70090.1 - 2.4e-09 37.4 8.8 2.1e-05 24.5 0.2 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMD70090.1 - 1.2e-08 34.2 2.0 0.0016 17.9 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EMD70090.1 - 3.3e-07 30.6 0.0 0.0076 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMD70090.1 - 4.9e-07 28.7 5.6 0.0086 14.7 0.0 4.1 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EMD70090.1 - 7.6e-07 29.3 3.8 0.0069 16.5 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMD70090.1 - 1.8e-05 24.4 0.9 0.036 13.6 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMD70090.1 - 2.4e-05 23.8 0.1 0.14 11.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EMD70090.1 - 3.1e-05 23.1 0.1 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EMD70090.1 - 5e-05 23.1 0.3 0.41 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.15 EMD70090.1 - 5.3e-05 22.0 0.0 0.012 14.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.1 EMD70090.1 - 0.00017 21.6 0.0 0.27 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMD70090.1 - 0.00027 20.4 2.7 1.9 7.8 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain AAA_5 PF07728.9 EMD70090.1 - 0.00027 20.6 0.2 1.8 8.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMD70090.1 - 0.0003 20.6 0.0 0.81 9.5 0.0 3.9 3 1 1 4 4 4 1 AAA domain DUF87 PF01935.12 EMD70090.1 - 0.00032 20.5 0.1 1.5 8.5 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 EMD70090.1 - 0.00064 19.5 3.4 0.6 10.0 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit PRK PF00485.13 EMD70090.1 - 0.0011 18.5 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EMD70090.1 - 0.003 17.2 0.0 2.9 7.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EMD70090.1 - 0.0038 16.7 0.2 2.8 7.3 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family APS_kinase PF01583.15 EMD70090.1 - 0.0048 16.5 0.1 2 8.0 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EMD70090.1 - 0.0049 15.9 0.5 1.9 7.5 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.18 EMD70090.1 - 0.0056 16.6 0.5 4.7 7.2 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase GCN5L1 PF06320.8 EMD70090.1 - 0.0057 16.4 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) AAA_15 PF13175.1 EMD70090.1 - 0.0064 15.5 0.0 2.1 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EMD70090.1 - 0.022 14.9 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EMD70090.1 - 0.036 14.4 2.6 4.4 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain CPT PF07931.7 EMD70090.1 - 0.038 13.6 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EMD70090.1 - 0.064 12.1 1.6 6 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EMD70090.1 - 0.12 12.0 1.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Lipocalin_2 PF08212.7 EMD70092.1 - 1.1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Hemerythrin PF01814.18 EMD70094.1 - 4.8e-11 42.9 0.7 6.8e-11 42.4 0.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MoeZ_MoeB PF05237.8 EMD70094.1 - 0.085 12.4 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain Actin PF00022.14 EMD70095.1 - 3.5e-131 437.2 0.0 4e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMD70095.1 - 0.00093 17.8 0.0 0.014 14.0 0.0 2.5 1 1 0 1 1 1 1 MreB/Mbl protein DUF3602 PF12223.3 EMD70096.1 - 9.9e-20 70.7 13.6 4.1e-16 59.1 0.3 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) SR-25 PF10500.4 EMD70096.1 - 0.024 14.1 5.2 0.029 13.8 3.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SLY PF12485.3 EMD70096.1 - 0.084 13.1 7.6 0.12 12.5 5.1 1.5 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein PNPase_C PF12111.3 EMD70096.1 - 4.3 6.6 10.3 2 7.6 0.1 3.6 4 0 0 4 4 4 0 Polyribonucleotide phosphorylase C terminal SH2_2 PF14633.1 EMD70097.1 - 6.9e-76 254.1 0.1 1.8e-75 252.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.1 EMD70097.1 - 7.5e-39 132.7 0.2 1.4e-37 128.5 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EMD70097.1 - 1.2e-33 115.6 3.0 1.2e-33 115.6 2.1 3.4 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EMD70097.1 - 6.3e-28 96.9 0.0 2.1e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EMD70097.1 - 8.2e-18 64.3 32.0 8.2e-18 64.3 22.2 4.5 5 1 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EMD70097.1 - 1.1e-15 57.7 1.6 4.4e-15 55.7 1.1 2.0 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EMD70097.1 - 0.00027 20.6 0.1 0.00069 19.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EMD70097.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Pkinase PF00069.20 EMD70098.1 - 2.7e-62 210.2 0.0 3.7e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70098.1 - 1.5e-38 132.3 0.0 2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMD70098.1 - 0.00026 20.0 0.0 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMD70098.1 - 0.021 14.5 0.0 0.099 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMD70098.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.2 EMD70099.1 - 0.00069 19.2 0.3 0.002 17.8 0.0 1.9 1 1 1 2 2 2 1 F-box-like DUF466 PF04328.8 EMD70099.1 - 0.16 11.7 1.3 0.43 10.4 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF466) Pkinase PF00069.20 EMD70100.1 - 6.5e-18 64.8 0.0 4.4e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70100.1 - 1.7e-07 30.5 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1376 PF07120.6 EMD70100.1 - 0.003 17.6 0.1 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1376) Solute_trans_a PF03619.11 EMD70101.1 - 6.5e-39 133.8 12.6 1.8e-38 132.4 8.7 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha WBP-1 PF11669.3 EMD70101.1 - 0.1 12.7 0.2 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 TT_ORF1 PF02956.9 EMD70101.1 - 0.19 10.1 0.1 0.28 9.5 0.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF4293 PF14126.1 EMD70101.1 - 4.3 7.2 12.2 0.12 12.2 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Cpn60_TCP1 PF00118.19 EMD70102.1 - 7.8e-161 535.9 2.7 8.9e-161 535.7 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peripla_BP_2 PF01497.13 EMD70102.1 - 0.1 11.7 1.0 2.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Periplasmic binding protein PLDc PF00614.17 EMD70105.1 - 2.2e-16 59.0 1.7 1.5e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMD70105.1 - 8.3e-13 48.1 0.0 2.6e-08 33.6 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EMD70105.1 - 4.2e-11 42.6 0.0 1.6e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 PX domain Abhydrolase_6 PF12697.2 EMD70106.1 - 3e-07 30.5 0.1 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMD70106.1 - 5.5e-05 22.9 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA PF08736.6 EMD70111.1 - 0.11 12.3 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 FERM adjacent (FA) MFS_1 PF07690.11 EMD70112.1 - 3.1e-32 111.6 32.7 3.1e-32 111.6 22.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0182 PF03699.8 EMD70112.1 - 0.02 12.8 0.1 0.032 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) F-box-like PF12937.2 EMD70113.1 - 8.9e-05 22.1 0.1 0.00025 20.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMD70113.1 - 0.00087 18.8 0.0 0.0029 17.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EMD70114.1 - 6.9e-33 113.8 28.6 9.6e-33 113.3 19.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EMD70114.1 - 0.069 12.2 4.7 0.17 11.0 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) EPSP_synthase PF00275.15 EMD70115.1 - 6e-124 413.6 0.0 8.9e-124 413.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EMD70115.1 - 1.3e-99 332.3 0.0 2e-99 331.7 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EMD70115.1 - 1.2e-59 201.7 0.0 2.2e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EMD70115.1 - 5.5e-38 130.3 0.0 9.4e-37 126.3 0.0 2.6 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 EMD70115.1 - 6.5e-22 77.3 0.0 1.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 EMD70115.1 - 7.7e-09 35.2 0.0 1.7e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 EMD70115.1 - 8.6e-09 35.6 0.0 2.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EMD70115.1 - 4.1e-06 27.6 0.0 1.6e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMD70115.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Iso_dh PF00180.15 EMD70117.1 - 2.6e-75 253.5 0.0 3.1e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3887 PF13026.1 EMD70117.1 - 0.3 11.3 2.5 7.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) VWA_3 PF13768.1 EMD70119.1 - 7e-30 103.7 0.0 1.3e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EMD70119.1 - 3.1e-20 72.0 0.0 1.2e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EMD70119.1 - 2.8e-16 60.1 0.0 6.4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMD70119.1 - 1.6e-10 40.9 0.0 2.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EMD70119.1 - 1.1e-07 31.1 0.0 2.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EMD70119.1 - 0.0013 17.9 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein PseudoU_synth_1 PF01416.15 EMD70120.1 - 4.9e-28 97.6 0.0 3e-20 72.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase ubiquitin PF00240.18 EMD70121.1 - 7.8e-06 25.1 0.0 8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Peptidase_S9 PF00326.16 EMD70121.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family DIM1 PF02966.11 EMD70122.1 - 1.9e-69 231.3 0.1 2.1e-69 231.1 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Ribosomal_L35Ae PF01247.13 EMD70123.1 - 4.3e-39 132.1 0.1 5e-39 131.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EMD70123.1 - 0.011 15.6 0.0 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain vATP-synt_AC39 PF01992.11 EMD70124.1 - 2.8e-114 381.7 0.0 3.2e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit zf-C2H2_2 PF12756.2 EMD70126.1 - 7.8e-25 86.9 1.9 6.3e-21 74.3 0.4 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMD70126.1 - 0.00055 19.9 2.5 0.04 14.0 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMD70126.1 - 0.085 13.2 0.6 0.085 13.2 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type FHA PF00498.21 EMD70127.1 - 2.8e-14 52.9 0.0 4.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Zw10 PF06248.8 EMD70127.1 - 0.3 9.1 0.2 0.41 8.7 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 RNA_pol_Rpb1_5 PF04998.12 EMD70128.1 - 4.5e-90 301.6 0.2 7.3e-90 300.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EMD70128.1 - 1.2e-83 281.1 0.0 1.9e-83 280.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EMD70128.1 - 1.8e-65 219.9 0.0 4.1e-65 218.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMD70128.1 - 1e-34 119.5 0.0 3.4e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMD70128.1 - 3.7e-27 94.2 0.0 1.4e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Ank_2 PF12796.2 EMD70129.1 - 7.6e-44 147.9 9.5 5.8e-16 58.6 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMD70129.1 - 1.2e-31 106.9 8.0 9.4e-05 22.0 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EMD70129.1 - 8e-25 86.7 6.6 1.6e-10 41.1 0.1 6.8 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMD70129.1 - 1.3e-20 71.4 4.5 0.0013 18.8 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EMD70129.1 - 2.3e-20 72.1 0.8 1.1e-07 31.8 0.0 5.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) ZZ PF00569.12 EMD70129.1 - 1.5e-07 30.8 0.3 1.5e-07 30.8 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type Beta-lactamase PF00144.19 EMD70131.1 - 4.6e-29 101.4 0.4 7e-29 100.8 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase SNF2_N PF00176.18 EMD70133.1 - 2.7e-20 72.3 0.0 2.9e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMD70134.1 - 1.7e-07 30.9 0.0 1.8e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CRPA PF05745.6 EMD70134.1 - 0.056 13.2 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) cNMP_binding PF00027.24 EMD70136.1 - 3e-43 145.5 0.0 3.2e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EMD70136.1 - 1.4e-09 37.1 0.1 3.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 EMD70136.1 - 0.035 13.1 0.1 0.079 11.9 0.1 1.5 2 0 0 2 2 2 0 GXGXG motif HET PF06985.6 EMD70139.1 - 1e-22 80.7 0.4 1.9e-22 79.9 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4560 PF15118.1 EMD70139.1 - 0.092 12.5 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) Lactamase_B PF00753.22 EMD70140.1 - 1.3e-11 44.5 0.1 2.2e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD70140.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 EMD70142.1 - 4.4e-125 403.6 65.5 2.4e-13 49.3 0.5 11.6 11 0 0 11 11 11 11 WD domain, G-beta repeat NACHT PF05729.7 EMD70142.1 - 8.2e-26 90.6 0.0 1.8e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EMD70142.1 - 3.3e-22 79.1 6.7 3.4e-20 72.6 4.6 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EMD70142.1 - 2.5e-17 62.2 37.5 0.0002 19.6 2.4 9.8 2 2 7 9 9 9 9 Nucleoporin Nup120/160 AAA_16 PF13191.1 EMD70142.1 - 0.011 15.6 0.4 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Asp_decarbox PF02261.11 EMD70142.1 - 0.036 13.6 0.0 32 4.1 0.0 4.4 3 2 0 4 4 4 0 Aspartate decarboxylase AAA_19 PF13245.1 EMD70142.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2_6 PF13912.1 EMD70142.1 - 3 7.8 7.4 32 4.5 0.0 5.4 7 0 0 7 7 7 0 C2H2-type zinc finger ADH_N PF08240.7 EMD70143.1 - 1.1e-24 86.2 2.2 2.2e-24 85.2 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMD70143.1 - 3.7e-17 62.1 0.0 5.5e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMD70143.1 - 9.3e-05 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMD70143.1 - 0.015 14.8 0.4 0.031 13.8 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EMD70143.1 - 0.017 15.0 0.2 0.054 13.3 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMD70143.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Med12 PF09497.5 EMD70144.1 - 0.028 14.3 0.4 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 TRP PF06011.7 EMD70145.1 - 2.7e-149 497.4 30.8 3.4e-149 497.1 21.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMD70145.1 - 3.4e-41 140.6 0.0 5.1e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EMD70145.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Pkinase PF00069.20 EMD70146.1 - 3.4e-11 42.8 0.0 9.1e-11 41.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70146.1 - 1.4e-07 30.8 0.0 6.2e-07 28.7 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase His_Phos_1 PF00300.17 EMD70147.1 - 5.9e-09 36.1 0.0 3.6e-08 33.6 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) MBF1 PF08523.5 EMD70148.1 - 2.5e-24 85.0 1.0 4.7e-24 84.2 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EMD70148.1 - 1.1e-07 31.5 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EMD70148.1 - 0.0033 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EMD70148.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 EMD70149.1 - 6e-29 98.8 0.6 1.7e-08 33.9 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EMD70149.1 - 0.00038 20.2 0.0 0.79 9.3 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MIR PF02815.14 EMD70149.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 MIR domain Gmad1 PF10647.4 EMD70149.1 - 0.095 12.0 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain FTHFS PF01268.14 EMD70151.1 - 3.6e-254 843.9 0.6 4.7e-254 843.5 0.4 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMD70151.1 - 4e-68 227.5 0.8 9.4e-68 226.3 0.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMD70151.1 - 3.1e-38 130.3 1.3 6.8e-38 129.2 0.9 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Trehalase PF01204.13 EMD70152.1 - 1.4e-192 640.9 0.0 1.7e-192 640.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EMD70152.1 - 2.9e-16 58.4 0.2 4.5e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lactamase_B PF00753.22 EMD70155.1 - 1.5e-08 34.5 1.2 4.2e-07 29.8 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMD70155.1 - 7.2e-06 25.6 0.3 2.3e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_2 PF03446.10 EMD70156.1 - 2e-30 105.7 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMD70156.1 - 1.7e-22 79.7 0.0 3.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMD70156.1 - 8.5e-05 22.9 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CMD PF02627.15 EMD70157.1 - 1.5e-21 76.0 0.1 3.1e-21 74.9 0.1 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.13 EMD70158.1 - 4.9e-12 45.2 1.4 6.1e-12 44.9 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain UQ_con PF00179.21 EMD70159.1 - 2.4e-20 72.4 0.0 4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EMD70159.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 UEV domain dsDNA_bind PF01984.15 EMD70159.1 - 0.09 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Dor1 PF04124.7 EMD70160.1 - 9.7e-54 182.0 1.4 2.7e-44 151.0 3.5 2.2 1 1 1 2 2 2 2 Dor1-like family Cellulase-like PF12876.2 EMD70160.1 - 0.048 14.0 3.6 0.11 13.0 0.2 3.2 4 1 1 5 5 5 0 Sugar-binding cellulase-like Peptidase_C69 PF03577.10 EMD70162.1 - 2.4e-27 95.8 0.1 4.5e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C69 Peptidase_S58 PF03576.9 EMD70163.1 - 1.4e-108 362.9 0.1 1.6e-108 362.7 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Soyouz_module PF14313.1 EMD70163.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) HMG_box PF00505.14 EMD70164.1 - 2.5e-09 37.2 1.0 6e-09 36.0 0.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_2 PF07647.12 EMD70164.1 - 2e-06 27.5 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMD70164.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Fungal_trans PF04082.13 EMD70164.1 - 0.0017 17.3 0.6 0.0035 16.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box_2 PF09011.5 EMD70164.1 - 0.002 18.4 1.6 0.0044 17.3 1.1 1.6 1 0 0 1 1 1 1 HMG-box domain FAM60A PF15396.1 EMD70164.1 - 0.16 11.7 1.9 0.27 10.9 1.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A adh_short PF00106.20 EMD70166.1 - 3.4e-27 95.3 0.9 4.6e-27 94.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMD70166.1 - 9e-24 84.5 0.1 1.2e-23 84.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMD70166.1 - 3.4e-08 33.3 0.2 5.8e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EMD70166.1 - 0.00088 18.3 0.1 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EMD70166.1 - 0.0042 16.5 0.0 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMD70166.1 - 0.041 13.0 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMD70166.1 - 0.059 13.3 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding AA_kinase PF00696.23 EMD70166.1 - 0.092 12.2 0.1 0.35 10.3 0.1 2.0 1 1 0 1 1 1 0 Amino acid kinase family BCAS2 PF05700.6 EMD70167.1 - 4.5e-38 130.9 0.4 5.4e-38 130.6 0.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Cep57_MT_bd PF06657.8 EMD70167.1 - 0.016 15.1 1.9 0.021 14.7 0.6 1.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.4 EMD70167.1 - 0.017 15.2 1.0 0.035 14.2 0.7 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 EMD70167.1 - 0.088 12.7 2.7 0.24 11.3 1.9 1.7 1 0 0 1 1 1 0 FlxA-like protein Ceramidase_alk PF04734.8 EMD70168.1 - 1.5e-281 935.2 0.0 1.7e-281 935.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase TMEM190 PF15431.1 EMD70169.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 190 Phage_CP76 PF06892.6 EMD70169.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DUF221 PF02714.10 EMD70170.1 - 5e-110 367.3 13.9 9.5e-110 366.4 9.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMD70170.1 - 8.3e-40 135.9 0.2 8.3e-40 135.9 0.1 2.5 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMD70170.1 - 2e-25 88.4 0.0 3.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMD70170.1 - 4.4e-18 65.5 0.8 8.8e-18 64.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) IncA PF04156.9 EMD70170.1 - 1.8 8.1 0.0 1.8 8.1 0.0 3.9 5 0 0 5 5 5 0 IncA protein Glyco_hydro_61 PF03443.9 EMD70171.1 - 7.2e-53 179.6 0.3 1e-52 179.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Asp PF00026.18 EMD70173.1 - 9.2e-09 34.9 0.1 1.4e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF347 PF03988.7 EMD70173.1 - 0.013 15.3 0.7 0.066 13.1 0.3 2.3 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Pkinase PF00069.20 EMD70174.1 - 4.9e-64 215.9 0.0 9.3e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.24 EMD70174.1 - 2e-43 147.8 0.0 5.2e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.12 EMD70174.1 - 1.1e-25 90.1 0.1 1.5e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4217 PF13959.1 EMD70174.1 - 2.9e-22 77.9 0.4 8e-22 76.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMD70174.1 - 6.5e-21 73.9 0.0 2e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HemY_N PF07219.8 EMD70174.1 - 0.026 14.0 2.1 0.058 12.9 1.5 1.6 1 0 0 1 1 1 0 HemY protein N-terminus APH PF01636.18 EMD70174.1 - 0.029 14.1 0.2 0.14 11.8 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF966 PF06136.8 EMD70174.1 - 2.6 7.3 10.5 4 6.7 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pox_Ag35 PF03286.9 EMD70174.1 - 7.4 6.0 14.4 13 5.2 9.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 EMD70174.1 - 8.5 4.7 14.7 13 4.0 10.2 1.2 1 0 0 1 1 1 0 Daxx Family zf-C2H2_6 PF13912.1 EMD70177.1 - 0.00019 21.2 5.1 0.00035 20.3 0.3 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 EMD70177.1 - 0.0003 20.4 5.6 0.23 11.2 0.1 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_4 PF13894.1 EMD70177.1 - 0.00084 19.5 5.1 0.0046 17.2 1.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMD70177.1 - 0.0015 18.7 2.0 0.0015 18.7 1.4 3.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMD70177.1 - 0.0028 17.7 0.6 0.0053 16.8 0.4 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.1 EMD70177.1 - 0.0063 16.0 0.4 0.19 11.3 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.1 EMD70177.1 - 0.062 13.6 6.8 0.073 13.3 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EMD70177.1 - 0.11 12.7 0.3 0.37 11.0 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Actin PF00022.14 EMD70178.1 - 4.3e-31 107.7 0.0 1.5e-30 105.9 0.0 1.8 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 EMD70178.1 - 0.00062 18.4 0.0 0.3 9.6 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EMD70178.1 - 0.0034 16.3 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FAM220 PF15487.1 EMD70178.1 - 0.0097 15.3 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 FAM220 family Nop PF01798.13 EMD70179.1 - 3e-54 182.3 1.7 1.2e-53 180.4 1.2 2.1 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMD70179.1 - 2.5e-24 84.8 0.1 4.8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMD70179.1 - 4.7e-18 65.0 1.2 1.9e-17 63.1 0.9 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF760 PF05542.6 EMD70179.1 - 0.0073 16.4 0.3 0.042 14.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF760) RNA_pol_Rpb4 PF03874.11 EMD70180.1 - 1.5e-19 70.1 0.0 2.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 SMC_Nse1 PF07574.8 EMD70180.1 - 0.059 12.9 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex zf-MYND PF01753.13 EMD70182.1 - 8.9e-09 35.0 17.6 1.6e-08 34.3 12.2 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 EMD70182.1 - 0.2 9.2 5.2 0.21 9.2 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C2HC5 PF06221.8 EMD70182.1 - 0.32 10.7 9.1 0.33 10.7 5.6 1.5 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DZR PF12773.2 EMD70182.1 - 3.3 7.5 11.5 16 5.3 8.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.1 EMD70182.1 - 6 6.8 10.1 12 5.8 6.9 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2 PF00096.21 EMD70182.1 - 10 6.7 9.9 40 4.8 3.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type GrpB PF04229.9 EMD70184.1 - 5.1e-40 136.9 0.1 8.4e-40 136.2 0.1 1.3 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.1 EMD70184.1 - 4.9e-24 85.1 0.0 7.2e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD70184.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMD70184.1 - 0.00084 19.3 0.1 0.0025 17.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMD70184.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD70184.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Repressor_Mnt PF11423.3 EMD70185.1 - 0.25 10.6 2.5 0.45 9.8 1.7 1.3 1 0 0 1 1 1 0 Regulatory protein Mnt EAF PF09816.4 EMD70186.1 - 8.4e-17 61.1 1.3 1.5e-16 60.3 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF515 PF04415.7 EMD70186.1 - 0.24 9.6 4.7 0.39 8.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Bys1 PF04681.7 EMD70187.1 - 1.9e-07 30.9 0.1 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pkinase PF00069.20 EMD70188.1 - 5.5e-16 58.4 0.0 9.3e-15 54.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70188.1 - 9.7e-10 37.9 0.0 2e-06 27.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_2_N PF02837.13 EMD70189.1 - 1.4e-29 102.7 0.2 2.8e-29 101.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMD70189.1 - 4e-13 48.9 0.0 1e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMD70189.1 - 1.2e-09 38.5 0.2 4e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMD70189.1 - 0.011 16.0 0.3 0.03 14.5 0.2 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Acetyltransf_3 PF13302.1 EMD70190.1 - 1e-13 51.6 0.0 1.5e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMD70190.1 - 1.6e-12 47.2 0.5 2.3e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMD70190.1 - 7.5e-09 35.7 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMD70190.1 - 3.6e-05 23.8 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMD70190.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EMD70190.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S15 PF00312.17 EMD70191.1 - 6.1e-17 61.1 0.3 1.6e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 SPATA25 PF15218.1 EMD70191.1 - 0.033 13.6 0.4 0.095 12.1 0.1 1.8 2 1 0 2 2 2 0 Spermatogenesis-associated protein 25 Ribosomal_S2 PF00318.15 EMD70192.1 - 8.3e-41 139.5 0.0 5.1e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Glyco_hydro_72 PF03198.9 EMD70193.1 - 2.3e-99 332.3 0.4 3e-99 331.9 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMD70193.1 - 0.00098 18.3 1.3 0.019 14.1 0.9 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.1 EMD70193.1 - 0.0077 15.9 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_2_C PF02836.12 EMD70193.1 - 0.044 12.6 0.2 0.087 11.7 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain PhnJ PF06007.6 EMD70195.1 - 0.068 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ HATPase_c PF02518.21 EMD70196.1 - 4.6e-22 77.8 0.0 1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMD70196.1 - 1.6e-17 63.5 0.1 2.5e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EMD70196.1 - 2.1e-11 43.6 0.0 7.3e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EMD70196.1 - 1.3e-06 28.4 0.7 0.0012 18.8 0.0 4.0 4 0 0 4 4 4 1 PAS fold GAF_3 PF13492.1 EMD70196.1 - 0.00033 20.7 0.0 0.0009 19.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.1 EMD70196.1 - 0.003 17.8 0.0 0.35 11.2 0.0 2.9 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EMD70196.1 - 0.025 15.0 0.0 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 GAF domain PAS PF00989.19 EMD70196.1 - 0.036 13.8 0.0 0.39 10.5 0.0 2.9 3 1 0 3 3 3 0 PAS fold PAS_3 PF08447.6 EMD70196.1 - 0.1 12.6 0.2 3.6 7.7 0.1 2.8 2 0 0 2 2 2 0 PAS fold Snapin_Pallidin PF14712.1 EMD70196.1 - 0.17 12.1 1.4 0.25 11.6 0.2 1.8 2 0 0 2 2 1 0 Snapin/Pallidin PUB PF09409.5 EMD70196.1 - 0.2 11.4 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 PUB domain Peroxidase_2 PF01328.12 EMD70197.1 - 2.6e-18 65.7 0.0 3.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans PF04082.13 EMD70198.1 - 2.1e-14 53.0 1.5 4.2e-14 52.0 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMD70198.1 - 4.7e-09 36.0 14.3 4.9e-05 23.4 3.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMD70198.1 - 6.4e-08 32.3 9.7 0.00024 21.2 2.1 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMD70198.1 - 0.0014 18.7 11.1 0.0042 17.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMD70198.1 - 0.0072 16.1 4.3 0.027 14.3 0.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMD70198.1 - 0.12 12.6 4.1 0.18 12.0 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Aldedh PF00171.17 EMD70199.1 - 7.1e-79 265.2 0.0 8.8e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GFO_IDH_MocA PF01408.17 EMD70200.1 - 5.7e-14 52.6 0.1 8.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMD70200.1 - 0.00036 20.9 0.1 0.00067 20.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Abhydrolase_4 PF08386.5 EMD70201.1 - 1.5e-14 53.7 0.0 3.6e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EMD70201.1 - 5.4e-08 32.9 0.0 2.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMD70201.1 - 7.8e-08 32.1 0.0 5.5e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMD70201.1 - 0.0028 17.3 0.0 0.11 12.2 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioredoxin PF00085.15 EMD70202.1 - 5.5e-28 96.6 0.1 7.1e-28 96.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMD70202.1 - 1e-10 41.5 0.2 5.8e-07 29.5 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMD70202.1 - 8.9e-08 32.3 0.1 2.7e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMD70202.1 - 5.5e-07 29.3 0.2 0.0027 17.3 0.1 2.2 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EMD70202.1 - 3.8e-06 26.8 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMD70202.1 - 1.3e-05 24.8 0.2 0.087 12.3 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EMD70202.1 - 7.8e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EMD70202.1 - 0.01 15.6 0.2 0.022 14.5 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EMD70202.1 - 0.021 14.8 0.1 2.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 EMD70202.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.6 EMD70202.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 EMD70202.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 EMD70202.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-PARP PF00645.13 EMD70203.1 - 1.9e-24 85.7 7.1 5.9e-14 52.0 0.5 2.6 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CALCOCO1 PF07888.6 EMD70204.1 - 0.00012 20.5 13.4 0.00015 20.2 9.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CCDC155 PF14662.1 EMD70204.1 - 0.0016 18.0 14.6 0.0025 17.4 10.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Tropomyosin PF00261.15 EMD70204.1 - 0.0058 15.7 7.9 0.0058 15.7 5.5 1.8 2 0 0 2 2 2 1 Tropomyosin ERM PF00769.14 EMD70204.1 - 0.012 15.1 11.4 0.018 14.5 7.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CCDC92 PF14916.1 EMD70204.1 - 0.013 15.1 0.7 0.013 15.1 0.5 3.0 1 1 2 3 3 3 0 Coiled-coil domain of unknown function V_ATPase_I PF01496.14 EMD70204.1 - 0.017 12.9 4.5 0.019 12.8 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2353 PF09789.4 EMD70204.1 - 0.028 13.6 12.0 0.047 12.9 8.2 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF837 PF05769.6 EMD70204.1 - 0.072 12.6 11.4 0.19 11.2 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF837) TMF_TATA_bd PF12325.3 EMD70204.1 - 0.079 12.6 16.0 0.37 10.5 0.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EMD70204.1 - 0.14 11.6 16.4 0.58 9.6 2.7 2.9 1 1 2 3 3 3 0 Septum formation initiator ADIP PF11559.3 EMD70204.1 - 0.23 11.3 23.1 0.32 10.8 7.9 2.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 EMD70204.1 - 0.32 9.3 5.9 0.44 8.8 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Striatin PF08232.7 EMD70204.1 - 0.53 10.5 16.5 0.35 11.1 9.0 2.0 1 1 1 2 2 2 0 Striatin family Ax_dynein_light PF10211.4 EMD70204.1 - 1.3 8.8 18.2 1.5 8.5 4.0 2.6 2 1 1 3 3 3 0 Axonemal dynein light chain DUF1664 PF07889.7 EMD70204.1 - 1.5 8.5 6.2 2 8.2 3.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2312 PF10073.4 EMD70204.1 - 1.8 7.9 8.7 0.79 9.1 0.5 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Viral_P18 PF04521.8 EMD70204.1 - 4 6.8 7.4 4.6 6.7 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HALZ PF02183.13 EMD70204.1 - 4.2 7.1 9.9 4.3 7.1 0.2 3.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Gon7 PF08738.5 EMD70204.1 - 8.5 6.4 14.2 0.38 10.7 5.5 2.0 2 0 0 2 2 2 0 Gon7 family bZIP_1 PF00170.16 EMD70204.1 - 9.8 6.2 14.3 5.3 7.0 0.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor FYVE PF01363.16 EMD70205.1 - 0.0019 18.0 4.6 0.0019 18.0 3.2 2.7 4 0 0 4 4 4 1 FYVE zinc finger DUF3454 PF11936.3 EMD70205.1 - 0.03 14.5 0.1 0.03 14.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3454) Amidohydro_4 PF13147.1 EMD70206.1 - 3.7e-19 69.8 0.1 1.2e-18 68.1 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMD70206.1 - 1e-11 45.1 0.3 1.1e-09 38.4 0.2 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMD70206.1 - 4e-09 36.1 0.0 1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMD70206.1 - 9.4e-07 28.3 3.8 0.00071 18.9 0.3 2.9 1 1 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.20 EMD70207.1 - 4.8e-58 196.3 0.0 6.7e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70207.1 - 5e-25 88.0 0.0 6.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMD70207.1 - 6e-05 22.8 0.1 0.016 14.9 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EMD70207.1 - 0.0014 18.0 1.2 0.0051 16.1 0.0 2.3 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.9 EMD70207.1 - 0.0014 17.7 0.0 0.003 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMD70207.1 - 0.015 14.8 0.0 0.049 13.2 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EMD70207.1 - 0.038 12.9 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Sugar_tr PF00083.19 EMD70208.1 - 2.5e-73 247.1 22.6 2.9e-73 246.9 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMD70208.1 - 3.5e-18 65.4 36.7 1.7e-10 40.1 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMD70208.1 - 2.3e-05 22.9 36.4 0.00039 18.9 4.9 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein tRNA-synt_1b PF00579.20 EMD70209.1 - 3.4e-21 75.6 0.0 5.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PRELI PF04707.9 EMD70210.1 - 1.3e-21 76.8 0.0 8.1e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family BTB PF00651.26 EMD70211.1 - 6.2e-08 32.6 0.7 3.2e-06 27.1 0.1 2.6 2 0 0 2 2 2 1 BTB/POZ domain PIN_2 PF10130.4 EMD70211.1 - 0.074 13.0 2.0 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 PIN domain Spc97_Spc98 PF04130.8 EMD70212.1 - 1.8e-118 396.2 0.0 2.3e-118 395.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family V-set_CD47 PF08204.6 EMD70212.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain PhyH PF05721.8 EMD70213.1 - 8.9e-09 35.6 0.1 3.2e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EMD70213.1 - 8e-05 21.2 0.2 1.4 7.3 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EMD70213.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ComJ PF11033.3 EMD70213.1 - 0.13 11.9 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Competence protein J (ComJ) FAD_binding_3 PF01494.14 EMD70214.1 - 1.6e-17 63.5 0.1 7.5e-17 61.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMD70214.1 - 4.3e-07 29.1 0.1 7.7e-05 21.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD70214.1 - 3.2e-05 23.8 0.1 0.00012 22.0 0.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMD70214.1 - 0.00014 20.8 0.2 0.00026 19.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMD70214.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMD70214.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMD70214.1 - 0.0057 15.3 0.1 0.81 8.2 0.1 2.8 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EMD70214.1 - 0.018 13.9 0.5 3 6.6 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 EMD70214.1 - 0.054 11.9 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMD70214.1 - 0.078 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMD70214.1 - 0.11 12.0 0.4 0.99 8.9 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 EMD70215.1 - 6e-27 94.2 21.3 6e-27 94.2 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMD70215.1 - 1.3e-05 23.6 2.6 1.3e-05 23.6 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Chitin_synth_1 PF01644.12 EMD70216.1 - 5.1e-83 276.7 1.0 9.8e-83 275.8 0.7 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMD70216.1 - 1.3e-30 104.9 0.0 2.9e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMD70216.1 - 1.6e-21 76.3 7.0 7.3e-19 67.5 0.1 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EMD70216.1 - 2.3e-10 40.6 0.0 1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMD70216.1 - 3.6e-10 39.8 12.0 3.7e-09 36.5 8.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pilus_CpaD PF09476.5 EMD70216.1 - 0.18 11.2 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) LMWPc PF01451.16 EMD70217.1 - 1.6e-27 96.4 0.0 2.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase BetaGal_dom3 PF13363.1 EMD70219.1 - 0.04 13.2 0.1 0.089 12.1 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 LAT PF15234.1 EMD70219.1 - 1.1 8.7 6.5 2.1 7.7 4.1 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells MFS_1 PF07690.11 EMD70220.1 - 3e-09 36.0 8.8 3e-09 36.0 6.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMD70220.1 - 0.0028 16.3 8.9 0.0028 16.3 6.1 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter AAA PF00004.24 EMD70221.1 - 1.5e-19 70.4 0.0 2.6e-17 63.2 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMD70221.1 - 0.00035 20.3 0.0 0.00084 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMD70221.1 - 0.0053 16.8 0.2 0.026 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMD70221.1 - 0.01 15.8 0.1 0.038 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EMD70221.1 - 0.029 15.1 0.3 0.18 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain zinc_ribbon_2 PF13240.1 EMD70221.1 - 0.045 13.2 5.4 0.1 12.1 3.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain AAA_14 PF13173.1 EMD70221.1 - 0.1 12.5 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMD70221.1 - 0.11 12.2 0.4 0.31 10.8 0.3 1.7 1 0 0 1 1 1 0 Part of AAA domain COMPASS-Shg1 PF05205.7 EMD70222.1 - 0.033 14.4 1.9 3.2 8.0 0.6 2.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 MFS_1 PF07690.11 EMD70223.1 - 3.5e-30 104.9 30.5 3.5e-30 104.9 21.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMD70223.1 - 0.0013 18.2 2.7 0.0024 17.3 1.9 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GNVR PF13807.1 EMD70223.1 - 8.4 6.2 5.6 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Pkinase PF00069.20 EMD70224.1 - 1.7e-75 253.5 0.0 2.4e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMD70224.1 - 4.7e-39 134.0 0.0 6.6e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EMD70224.1 - 1.3e-18 66.8 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EMD70224.1 - 3.6e-07 29.4 0.0 7.6e-06 25.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EMD70224.1 - 0.0013 18.1 0.2 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMD70224.1 - 0.014 14.4 0.1 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EMD70224.1 - 0.026 13.0 0.1 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EMD70224.1 - 0.031 13.9 0.5 0.18 11.5 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_11 PF13414.1 EMD70225.1 - 3.8e-47 157.8 28.3 3.3e-12 45.8 1.9 6.5 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMD70225.1 - 2.2e-34 115.6 29.0 0.00033 20.1 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMD70225.1 - 4.3e-34 113.6 26.1 0.00022 20.8 0.0 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EMD70225.1 - 8.6e-24 83.6 11.0 3e-05 24.5 0.1 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMD70225.1 - 1.5e-20 72.8 23.7 2.4e-08 33.7 0.0 7.3 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMD70225.1 - 2e-17 61.8 13.4 0.0017 18.3 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMD70225.1 - 9.4e-12 43.8 15.3 0.11 12.3 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMD70225.1 - 1.2e-11 44.1 15.9 0.04 14.5 0.2 7.8 5 3 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMD70225.1 - 2.3e-10 40.6 20.9 1.1e-06 28.8 0.2 6.5 4 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMD70225.1 - 7e-10 37.9 18.7 0.056 13.2 0.1 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EMD70225.1 - 8e-09 35.5 17.9 0.0001 22.3 0.1 5.3 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMD70225.1 - 1e-08 34.8 14.7 0.00066 19.4 0.3 6.1 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMD70225.1 - 3.1e-05 23.7 4.2 1.2 9.1 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMD70225.1 - 0.0019 17.3 10.0 0.61 9.3 0.0 5.7 7 0 0 7 7 7 1 SHNi-TPR TPR_6 PF13174.1 EMD70225.1 - 0.01 16.2 18.2 4.5 7.9 0.3 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMD70225.1 - 0.4 10.5 10.7 31 4.4 0.3 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HET PF06985.6 EMD70226.1 - 2.7e-21 76.2 0.5 5.5e-21 75.1 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_4 PF01063.14 EMD70227.1 - 5.1e-16 58.8 0.2 3.3e-12 46.3 0.2 2.9 2 1 0 2 2 2 2 Aminotransferase class IV Tyrosinase PF00264.15 EMD70229.1 - 5.6e-48 164.0 0.1 9.9e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.14 EMD70229.1 - 1.2e-14 54.1 0.1 1.3e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMD70229.1 - 0.00098 18.1 0.0 0.073 11.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMD70229.1 - 0.082 12.9 3.7 0.12 12.4 0.2 3.0 3 1 1 4 4 4 0 NAD(P)-binding Rossmann-like domain DUF3455 PF11937.3 EMD70231.1 - 9e-31 107.1 1.3 1.2e-30 106.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) p450 PF00067.17 EMD70232.1 - 8.4e-59 199.2 0.0 9.6e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2621 PF11084.3 EMD70232.1 - 0.066 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) PipA PF07108.6 EMD70232.1 - 0.16 11.3 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 PipA protein Ten1 PF12658.2 EMD70233.1 - 3.7e-35 120.3 0.0 4.1e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EMD70233.1 - 3.2e-07 29.9 0.0 4.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EMD70233.1 - 0.00061 19.6 0.0 0.00074 19.3 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Snf7 PF03357.16 EMD70234.1 - 4.7e-41 140.0 18.3 4.7e-41 140.0 12.7 2.0 1 1 1 2 2 2 1 Snf7 Rhamno_transf PF11316.3 EMD70234.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative rhamnosyl transferase Ribosomal_60s PF00428.14 EMD70234.1 - 0.66 10.4 6.3 0.17 12.3 1.2 2.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein Syntaxin-6_N PF09177.6 EMD70234.1 - 1.1 9.6 8.5 0.34 11.3 2.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2229 PF09989.4 EMD70234.1 - 9.2 5.6 7.3 9 5.6 3.5 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Fork_head PF00250.13 EMD70235.1 - 4e-21 74.8 0.2 1e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMD70235.1 - 7.9e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.1 EMD70236.1 - 3.6e-10 40.2 0.0 5.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMD70236.1 - 4.3e-08 32.6 0.0 7.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMD70236.1 - 0.0082 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EMD70238.1 - 7.3e-30 103.8 30.1 1.1e-29 103.2 20.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AKNA PF12443.3 EMD70238.1 - 0.031 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor BTP PF05232.7 EMD70238.1 - 0.046 13.4 0.4 0.046 13.4 0.2 3.3 3 1 0 3 3 3 0 Bacterial Transmembrane Pair family Methyltransf_25 PF13649.1 EMD70240.1 - 1.2e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMD70240.1 - 0.00029 21.2 0.0 0.00054 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMD70240.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_3 PF00202.16 EMD70241.1 - 1.6e-95 319.8 0.0 1.8e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 EMD70242.1 - 1.4e-12 47.0 0.0 2.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2838 PF10998.3 EMD70244.1 - 0.12 12.2 0.4 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Peptidase_S28 PF05577.7 EMD70245.1 - 2.1e-30 105.6 1.4 4e-30 104.7 1.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 p450 PF00067.17 EMD70247.1 - 8.5e-16 57.5 0.0 9.5e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMD70248.1 - 7.7e-11 41.1 0.0 7.8e-11 41.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_92 PF07971.7 EMD70250.1 - 2.8e-155 517.7 4.2 3.5e-155 517.4 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RNase_H PF00075.19 EMD70252.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase H CRF PF00473.12 EMD70253.1 - 0.13 12.3 1.2 0.24 11.5 0.8 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family