# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Acyl_transf_1 PF00698.16 KIA75322.1 - 1e-34 120.3 0.0 1.7e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75322.1 - 3.3e-33 115.1 0.0 2e-29 102.6 0.0 3.0 2 1 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KIA75322.1 - 0.00019 21.8 0.0 0.021 15.3 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75322.1 - 0.016 15.6 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75322.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KIA75322.1 - 0.056 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family ketoacyl-synt PF00109.21 KIA75323.1 - 5.1e-69 232.5 0.6 5.1e-68 229.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75323.1 - 1.4e-49 169.1 1.2 2.7e-49 168.2 0.4 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA75323.1 - 1.9e-30 105.1 2.1 4.5e-30 103.9 1.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KIA75323.1 - 2.2e-09 37.4 0.8 5.1e-09 36.2 0.6 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA75323.1 - 0.0025 16.8 0.1 0.0064 15.4 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KIA75324.1 - 7.8e-09 35.9 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75324.1 - 1.7e-07 31.6 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75324.1 - 8e-07 29.6 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75324.1 - 4e-06 26.4 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75324.1 - 4.8e-05 23.1 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75324.1 - 0.00024 21.4 0.0 0.00048 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KIA75324.1 - 0.056 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain SnoaL_2 PF12680.2 KIA75325.1 - 4.4e-06 27.0 0.1 8.4e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KIA75325.1 - 0.0027 17.7 0.3 0.0067 16.4 0.2 1.8 1 1 0 1 1 1 1 SnoaL-like domain RIP PF00161.14 KIA75325.1 - 0.07 12.3 0.0 0.076 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosome inactivating protein NAD_binding_10 PF13460.1 KIA75326.1 - 8.9e-16 58.4 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KIA75326.1 - 3e-06 26.6 0.0 5.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KIA75326.1 - 0.00098 17.9 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KIA75326.1 - 0.004 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KIA75326.1 - 0.08 11.8 0.0 0.24 10.2 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 KIA75326.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KIA75327.1 - 4.9e-29 101.3 0.8 7.2e-29 100.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75327.1 - 9.9e-26 90.9 0.1 1.2e-25 90.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75327.1 - 4.4e-11 42.7 0.3 6.2e-11 42.2 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KIA75327.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Scytalone_dh PF02982.9 KIA75328.1 - 9.6e-44 148.7 0.1 2e-26 92.5 0.0 2.0 1 1 1 2 2 2 2 Scytalone dehydratase SnoaL_4 PF13577.1 KIA75328.1 - 4.1e-06 26.7 0.0 0.00012 21.9 0.0 2.1 1 1 0 1 1 1 1 SnoaL-like domain p450 PF00067.17 KIA75329.1 - 2e-68 231.0 0.0 2.4e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1993 PF09351.5 KIA75329.1 - 3.6e-29 101.7 0.0 5.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) YebG PF07130.7 KIA75329.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 YebG protein WVELL PF14043.1 KIA75330.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 WVELL protein MFS_1 PF07690.11 KIA75331.1 - 2.6e-41 141.5 42.7 2.6e-41 141.5 29.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KIA75331.1 - 8.2e-10 37.5 22.4 1.2e-09 36.9 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KIA75331.1 - 6e-09 34.9 36.3 8.3e-09 34.5 9.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter AflR PF08493.5 KIA75332.1 - 1.1e-11 44.2 12.1 6.4e-11 41.8 7.6 2.5 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KIA75332.1 - 2.2e-07 30.6 9.7 2.2e-07 30.6 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4243 PF14027.1 KIA75333.1 - 8.6e-81 271.9 0.1 1e-80 271.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) adh_short PF00106.20 KIA75334.1 - 3.2e-07 30.3 0.0 5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75334.1 - 8.9e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KIA75334.1 - 9.8e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.22 KIA75335.1 - 1.2e-21 77.2 5.7 1.9e-21 76.6 3.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KIA75335.1 - 9.7e-05 21.9 1.9 0.00018 21.0 1.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KIA75335.1 - 0.00089 19.0 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.6 KIA75336.1 - 9.9e-24 83.6 2.2 1.4e-23 83.1 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DcuC PF03606.10 KIA75336.1 - 0.0097 14.1 2.0 0.014 13.6 1.4 1.2 1 1 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Cytochrom_C_asm PF01578.15 KIA75336.1 - 1.5 8.3 6.2 0.35 10.3 1.4 1.8 2 0 0 2 2 2 0 Cytochrome C assembly protein EthD PF07110.6 KIA75337.1 - 9.8e-21 74.5 0.4 1.2e-20 74.2 0.3 1.1 1 0 0 1 1 1 1 EthD domain MarR PF01047.17 KIA75338.1 - 0.0069 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 KIA75338.1 - 0.0091 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 KIA75338.1 - 0.016 14.7 0.0 0.065 12.8 0.0 2.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.2 KIA75338.1 - 0.025 14.2 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 KIA75338.1 - 0.049 13.9 0.0 0.38 11.1 0.0 2.5 3 0 0 3 3 3 0 Winged helix DNA-binding domain ABC_tran PF00005.22 KIA75339.1 - 5e-48 162.8 0.0 8.3e-28 97.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KIA75339.1 - 7.8e-47 159.9 36.6 2.9e-25 89.2 14.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KIA75339.1 - 4.1e-09 36.8 0.2 0.19 11.6 0.0 4.2 3 1 0 3 3 3 3 AAA domain MMR_HSR1 PF01926.18 KIA75339.1 - 2.1e-06 27.6 0.2 0.039 13.9 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KIA75339.1 - 3.5e-06 27.5 0.2 0.098 13.1 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 KIA75339.1 - 4.5e-06 25.8 0.0 0.0039 16.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 KIA75339.1 - 5.3e-06 25.8 0.9 0.12 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KIA75339.1 - 8.6e-06 26.5 0.0 0.073 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KIA75339.1 - 1.7e-05 24.1 1.7 0.88 8.7 0.1 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KIA75339.1 - 2.3e-05 24.8 0.5 0.46 10.7 0.1 3.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KIA75339.1 - 4e-05 23.6 0.4 0.34 10.8 0.4 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 KIA75339.1 - 5.9e-05 22.9 0.6 0.066 13.0 0.0 3.5 3 1 0 3 3 3 1 Dynamin family DUF258 PF03193.11 KIA75339.1 - 0.00011 21.4 0.1 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KIA75339.1 - 0.00073 18.9 0.1 0.13 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KIA75339.1 - 0.0012 17.6 1.0 0.038 12.7 0.5 2.4 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 KIA75339.1 - 0.0012 18.3 0.1 0.85 9.0 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KIA75339.1 - 0.004 16.6 0.2 2 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 KIA75339.1 - 0.0074 16.1 1.2 0.22 11.2 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KIA75339.1 - 0.0099 16.0 1.0 12 6.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.1 KIA75339.1 - 0.035 14.3 0.5 10 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KIA75339.1 - 0.1 12.2 0.2 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KIA75339.1 - 0.12 11.4 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Bunya_G2 PF03563.8 KIA75339.1 - 0.18 10.6 1.2 0.34 9.7 0.9 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 ATP_bind_1 PF03029.12 KIA75339.1 - 0.2 11.1 1.3 13 5.2 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KIA75339.1 - 0.32 10.9 0.0 0.32 10.9 0.0 3.1 4 0 0 4 4 2 0 AAA domain TOBE PF03459.12 KIA75340.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 TOBE domain AMP-binding PF00501.23 KIA75341.1 - 6.5e-35 120.3 0.0 1.4e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KIA75341.1 - 2.2e-28 98.8 0.0 3.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KIA75341.1 - 8.4e-06 25.3 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KIA75341.1 - 0.0098 15.8 0.2 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KIA75341.1 - 0.02 13.7 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PP-binding PF00550.20 KIA75341.1 - 0.032 14.4 0.0 0.23 11.7 0.0 2.4 2 1 0 2 2 2 0 Phosphopantetheine attachment site KR PF08659.5 KIA75341.1 - 0.048 13.3 0.4 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain Myb_DNA-bind_6 PF13921.1 KIA75342.1 - 7e-34 115.7 3.7 1.7e-15 56.8 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KIA75342.1 - 4.2e-29 100.3 10.0 1.3e-08 34.7 0.0 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KIA75342.1 - 0.00045 20.3 1.7 0.16 12.1 0.1 3.2 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.6 KIA75342.1 - 0.025 14.3 1.5 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 KIA75342.1 - 0.13 12.4 10.2 0.45 10.6 1.9 3.6 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3606 PF12244.3 KIA75342.1 - 0.14 11.8 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Myb_DNA-bind_5 PF13873.1 KIA75342.1 - 0.62 9.9 6.8 2.5 8.0 1.0 3.9 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 KIA75342.1 - 0.69 9.8 7.9 9.7 6.1 0.7 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ketoacyl-synt PF00109.21 KIA75343.1 - 1e-72 244.6 0.1 2e-72 243.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75343.1 - 2.3e-36 124.2 2.4 5.9e-36 122.9 1.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KIA75343.1 - 1.7e-34 119.6 0.2 2.3e-32 112.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KIA75343.1 - 5.5e-18 64.9 6.6 1.1e-08 35.2 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 KIA75343.1 - 4e-17 62.4 0.0 4.5e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KIA75343.1 - 5.3e-14 52.2 1.0 2.6e-10 40.1 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA75343.1 - 8.8e-11 41.4 0.0 9.3e-07 28.2 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KIA75343.1 - 8.5e-09 35.6 2.0 1.3e-07 31.7 0.2 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KIA75343.1 - 2e-05 24.1 0.0 0.091 12.1 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 KIA75343.1 - 0.00082 18.7 0.0 0.62 9.3 0.0 3.2 3 0 0 3 3 3 1 Dienelactone hydrolase family Thiolase_N PF00108.18 KIA75343.1 - 0.0032 16.5 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lipase_3 PF01764.20 KIA75343.1 - 0.05 13.2 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) LIP PF03583.9 KIA75343.1 - 0.053 12.7 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Thioesterase PF00975.15 KIA75343.1 - 0.084 13.0 0.4 3.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Thioesterase domain adh_short_C2 PF13561.1 KIA75344.1 - 3.4e-33 115.4 0.2 4.5e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75344.1 - 1.2e-27 96.8 0.3 1.5e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75344.1 - 7.5e-11 42.0 0.2 1.6e-10 40.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75344.1 - 0.00029 20.3 0.2 0.0028 17.1 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KIA75344.1 - 0.0037 17.0 0.3 0.0093 15.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_1_2 PF00155.16 KIA75344.1 - 0.016 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Flavodoxin_1 PF00258.20 KIA75344.1 - 0.025 14.5 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin NAD_binding_10 PF13460.1 KIA75344.1 - 0.036 14.0 1.3 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 NADH(P)-binding Saccharop_dh PF03435.13 KIA75344.1 - 0.12 11.2 0.3 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TauD PF02668.11 KIA75345.1 - 6.4e-32 111.2 0.3 9.1e-32 110.7 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KIA75345.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 KIA75346.1 - 4.7e-51 173.5 27.8 4.7e-51 173.5 19.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75346.1 - 1.4e-15 56.8 5.1 1.4e-15 56.8 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2583 PF10762.4 KIA75346.1 - 0.015 15.4 1.1 0.073 13.2 0.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) p450 PF00067.17 KIA75347.1 - 1.6e-75 254.4 0.0 2.5e-51 174.6 0.0 4.5 1 1 3 4 4 4 4 Cytochrome P450 Fungal_trans PF04082.13 KIA75348.1 - 3e-26 91.8 0.1 4.8e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 KIA75349.1 - 9.7e-71 238.5 0.0 1.2e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KIA75349.1 - 0.0044 15.8 0.5 0.045 12.5 0.0 2.2 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Glyco_hydro_28 PF00295.12 KIA75350.1 - 1.2e-40 139.4 4.9 4.9e-40 137.4 3.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Fungal_trans PF04082.13 KIA75351.1 - 3.1e-09 36.1 0.1 4.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 KIA75352.1 - 8.2e-154 500.4 38.6 1.8e-17 63.4 0.4 13.7 5 3 9 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75352.1 - 1.1e-107 346.9 79.3 6.2e-05 22.6 0.0 33.0 34 0 0 34 34 33 28 Ankyrin repeat Ank_4 PF13637.1 KIA75352.1 - 5.9e-90 294.2 37.6 3.3e-09 36.9 0.2 21.4 8 6 14 23 23 23 20 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75352.1 - 3.2e-72 231.2 46.8 0.00075 19.4 0.0 31.5 32 0 0 32 32 31 14 Ankyrin repeat Ank_5 PF13857.1 KIA75352.1 - 1.6e-58 193.4 63.1 1.4e-07 31.5 0.6 23.7 6 3 19 28 28 27 18 Ankyrin repeats (many copies) HATPase_c PF02518.21 KIA75352.1 - 7.9e-19 67.4 0.9 2e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.20 KIA75352.1 - 5.2e-17 62.2 0.0 3.8e-16 59.4 0.0 2.7 1 0 0 1 1 1 1 short chain dehydrogenase Response_reg PF00072.19 KIA75352.1 - 1.1e-12 47.9 0.0 7.1e-11 42.1 0.0 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KIA75352.1 - 3.6e-12 46.0 0.3 1.2e-11 44.4 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain adh_short_C2 PF13561.1 KIA75352.1 - 4.8e-11 42.8 0.4 2.6e-10 40.4 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75352.1 - 3.8e-09 36.4 0.3 1.6e-08 34.4 0.2 2.1 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KIA75352.1 - 4.2e-09 35.6 0.2 7.5e-09 34.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 KIA75352.1 - 2.8e-05 23.8 0.0 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KIA75352.1 - 0.003 17.6 0.1 0.027 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain gag-asp_proteas PF13975.1 KIA75352.1 - 0.017 14.9 10.5 38 4.2 0.0 6.8 8 0 0 8 8 8 0 gag-polyprotein putative aspartyl protease EAV_GS PF01309.13 KIA75352.1 - 0.063 12.7 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein AdoHcyase PF05221.12 KIA75352.1 - 0.14 11.0 0.0 0.4 9.5 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase 3Beta_HSD PF01073.14 KIA75352.1 - 0.25 10.0 0.1 0.46 9.1 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GST_N_3 PF13417.1 KIA75353.1 - 5.5e-07 29.7 0.0 9.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KIA75353.1 - 5.6e-07 29.6 0.0 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KIA75353.1 - 4.8e-05 23.1 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KIA75353.1 - 6.4e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KIA75353.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KIA75353.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 KIA75354.1 - 0.009 16.3 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) OTT_1508_deam PF14441.1 KIA75355.1 - 1.7e-11 44.0 0.1 6.5e-11 42.2 0.0 2.0 3 0 0 3 3 3 1 OTT_1508-like deaminase AMP-binding PF00501.23 KIA75356.1 - 9.9e-58 195.4 0.0 1.4e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 KIA75356.1 - 2.5e-24 86.7 0.0 1.4e-23 84.2 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KIA75356.1 - 2e-08 34.3 0.5 7.3e-08 32.5 0.4 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 KIA75356.1 - 0.026 14.2 0.0 0.078 12.7 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_2 PF03446.10 KIA75357.1 - 4.5e-24 85.1 0.0 1e-23 84.0 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KIA75357.1 - 1.9e-08 34.4 1.3 1.9e-07 31.1 0.9 2.1 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Methyltransf_2 PF00891.13 KIA75358.1 - 8.6e-34 116.7 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KIA75358.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 KIA75359.1 - 4.5e-67 226.5 0.0 8.6e-67 225.6 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.7 KIA75359.1 - 6.6e-11 42.1 0.0 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 KIA75359.1 - 0.0077 15.0 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KIA75359.1 - 0.008 16.1 0.2 0.026 14.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KIA75359.1 - 0.0094 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KIA75359.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KIA75359.1 - 0.032 13.0 0.3 0.056 12.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KIA75359.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KIA75359.1 - 0.19 10.6 0.0 0.9 8.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KIA75359.1 - 0.19 10.2 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Trp_DMAT PF11991.3 KIA75360.1 - 1.3e-89 300.9 0.0 1.6e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.18 KIA75361.1 - 9.9e-18 63.9 3.1 1.9e-17 63.0 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75361.1 - 1.7e-07 31.0 0.1 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_1_2 PF00155.16 KIA75362.1 - 3.3e-66 223.7 0.0 4e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 KIA75362.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain adh_short_C2 PF13561.1 KIA75363.1 - 1.2e-25 90.6 0.1 1.7e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75363.1 - 7e-24 84.6 1.3 1.2e-23 83.8 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75363.1 - 1e-10 41.5 1.7 5.2e-10 39.2 1.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75363.1 - 0.00019 20.9 0.1 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KIA75363.1 - 0.0064 15.6 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KIA75363.1 - 0.014 15.4 0.3 0.039 13.9 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 KIA75363.1 - 0.033 13.8 0.2 0.054 13.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KIA75363.1 - 0.072 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KIA75364.1 - 3.5e-09 35.9 0.7 7.2e-09 34.8 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75364.1 - 0.062 13.2 6.0 0.12 12.3 4.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec61_beta PF03911.11 KIA75365.1 - 0.0077 16.0 0.8 0.025 14.4 0.6 1.8 1 0 0 1 1 1 1 Sec61beta family Amidohydro_2 PF04909.9 KIA75366.1 - 1.2e-24 87.3 0.1 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase KNTase_C PF07827.6 KIA75366.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 KNTase C-terminal domain Sugar_tr PF00083.19 KIA75367.1 - 1.1e-79 268.1 21.4 1.3e-79 267.9 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75367.1 - 1.1e-13 50.6 31.2 1.1e-13 50.6 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AvrB_AvrC PF05394.6 KIA75367.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Avirulence protein Adeno_E3_14_5 PF04834.7 KIA75367.1 - 9.3 6.7 8.1 3.5 8.1 0.5 3.5 3 1 0 3 3 3 0 Early E3 14.5 kDa protein Amidohydro_2 PF04909.9 KIA75368.1 - 1.6e-23 83.6 0.0 2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.22 KIA75369.1 - 3.4e-55 183.7 10.1 4e-21 74.5 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2232 PF09991.4 KIA75369.1 - 0.11 11.5 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Fungal_trans PF04082.13 KIA75370.1 - 3.2e-17 62.2 1.1 5.7e-17 61.4 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75370.1 - 8.6e-10 38.3 11.2 1.6e-09 37.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_4 PF13577.1 KIA75372.1 - 3.7e-15 55.9 0.6 4.8e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KIA75372.1 - 1.3e-08 35.0 0.7 2e-08 34.4 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KIA75372.1 - 2.8e-05 24.4 1.0 4.3e-05 23.8 0.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.9 KIA75372.1 - 0.00029 20.4 0.5 0.00064 19.3 0.4 1.5 1 1 0 1 1 1 1 Scytalone dehydratase SnoaL_3 PF13474.1 KIA75372.1 - 0.0022 18.0 1.7 0.0065 16.4 1.2 1.7 1 1 0 1 1 1 1 SnoaL-like domain Transferase PF02458.10 KIA75373.1 - 3.9e-19 68.4 0.0 8.3e-19 67.3 0.0 1.4 1 1 0 1 1 1 1 Transferase family Tmemb_55A PF09788.4 KIA75374.1 - 0.57 9.2 4.4 0.99 8.4 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 55A DUF4481 PF14800.1 KIA75374.1 - 8.9 5.1 8.4 1.2 8.0 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) KR PF08659.5 KIA75375.1 - 1.1e-57 194.6 0.9 1.1e-57 194.6 0.6 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KIA75375.1 - 9.9e-57 192.6 0.0 1.5e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KIA75375.1 - 1.5e-44 151.8 0.5 5.2e-44 150.0 0.4 2.1 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KIA75375.1 - 3.4e-44 151.1 0.6 5.4e-44 150.5 0.4 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75375.1 - 2.5e-38 130.5 0.3 1.2e-37 128.3 0.0 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 KIA75375.1 - 1.4e-34 119.7 1.1 1e-21 77.6 0.0 3.6 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.7 KIA75375.1 - 8.4e-17 61.4 0.0 3.1e-16 59.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75375.1 - 6.6e-12 45.4 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75375.1 - 4.2e-11 42.6 0.0 1.3e-10 41.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75375.1 - 2.3e-10 41.0 0.1 9.7e-09 35.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KIA75375.1 - 5.2e-09 36.2 0.1 1.4e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KIA75375.1 - 8.1e-09 35.8 0.0 2.3e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75375.1 - 0.00041 19.5 0.0 0.00079 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KIA75375.1 - 0.00047 20.1 0.3 0.0025 17.8 0.2 2.4 1 0 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.15 KIA75375.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KIA75375.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 KIA75375.1 - 0.26 10.1 0.0 0.45 9.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein JCAD PF15351.1 KIA75375.1 - 3.8 4.9 0.0 6 4.3 0.0 1.2 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease FAD_binding_4 PF01565.18 KIA75376.1 - 3.1e-22 78.5 0.8 5.5e-22 77.7 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75376.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like AMP-binding PF00501.23 KIA75377.1 - 2.7e-78 263.2 0.0 4.1e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KIA75377.1 - 4.6e-25 88.0 0.0 6.5e-24 84.3 0.0 2.6 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.20 KIA75377.1 - 4.3e-07 30.0 0.1 9.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pro_CA PF00484.14 KIA75378.1 - 3e-21 76.0 0.0 3.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Arg_repressor_C PF02863.13 KIA75378.1 - 0.12 11.8 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF2278 PF10042.4 KIA75379.1 - 1.2e-72 243.9 0.0 1.5e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 KIA75379.1 - 3.1e-07 30.4 0.0 1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Lamin Tail Domain Abhydrolase_3 PF07859.8 KIA75380.1 - 1.1e-32 113.3 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KIA75380.1 - 6.9e-06 25.4 0.0 0.079 12.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KIA75380.1 - 4.7e-05 23.3 0.2 7.8e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA75380.1 - 0.00011 21.5 0.0 0.00037 19.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KIA75380.1 - 0.0045 16.7 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KIA75380.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KIA75380.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 KIA75380.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Zn_clus PF00172.13 KIA75381.1 - 1.6e-05 24.7 10.5 4.4e-05 23.3 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KIA75381.1 - 6.4e-05 21.7 0.4 0.0012 17.4 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Peptidase_M19 PF01244.16 KIA75382.1 - 2.9e-103 345.1 0.0 3.9e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.17 KIA75382.1 - 2.8e-47 161.2 0.0 4.3e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KIA75382.1 - 2e-38 132.0 49.1 4.7e-38 130.8 34.1 1.7 1 0 0 1 1 1 1 Major Facilitator Superfamily AIG2_2 PF13772.1 KIA75382.1 - 3.1e-07 30.4 0.1 1.9e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 AIG2-like family Sugar_tr PF00083.19 KIA75382.1 - 8.5e-06 24.5 12.0 8.5e-06 24.5 8.3 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Aminotran_1_2 PF00155.16 KIA75383.1 - 1.6e-29 103.0 0.0 7.9e-29 100.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KIA75383.1 - 0.0029 16.8 0.0 0.0042 16.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Methyltransf_2 PF00891.13 KIA75384.1 - 6.3e-39 133.6 0.0 1e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase GST_N_2 PF13409.1 KIA75384.1 - 8.9e-06 25.6 0.0 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KIA75384.1 - 4e-05 23.7 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_18 PF12847.2 KIA75384.1 - 4.6e-05 23.9 0.1 0.0011 19.4 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain GST_C_2 PF13410.1 KIA75384.1 - 0.0002 21.2 2.5 0.00059 19.6 0.2 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KIA75384.1 - 0.00063 19.8 0.0 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 KIA75384.1 - 0.00078 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GST_C PF00043.20 KIA75384.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 KIA75384.1 - 0.0066 16.0 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Prenyltrans_1 PF13243.1 KIA75384.1 - 0.031 14.2 0.3 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase-like HTH_9 PF08221.6 KIA75384.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain GST_C_3 PF14497.1 KIA75384.1 - 0.062 13.7 0.1 0.24 11.8 0.1 2.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_12 PF08242.7 KIA75384.1 - 0.11 12.9 0.1 0.61 10.6 0.0 2.3 3 0 0 3 3 2 0 Methyltransferase domain p450 PF00067.17 KIA75385.1 - 1.1e-42 146.1 0.0 1.4e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF773 PF05600.7 KIA75385.1 - 0.2 10.4 0.1 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) AMP-binding PF00501.23 KIA75386.1 - 9.9e-77 258.0 0.0 1.5e-76 257.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KIA75386.1 - 1.1e-53 182.0 0.1 7.6e-29 100.4 0.1 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KIA75386.1 - 3.6e-20 71.9 1.6 1.2e-12 47.9 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KIA75386.1 - 9.9e-07 29.0 0.0 2.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 KIA75386.1 - 1.4e-05 25.9 0.0 3.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1857 PF08982.6 KIA75388.1 - 2.2e-28 98.7 0.0 2.5e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) p450 PF00067.17 KIA75389.1 - 1.7e-61 208.1 0.0 1.3e-60 205.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.11 KIA75390.1 - 9.9e-18 63.9 52.2 3.7e-17 62.0 34.5 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KIA75390.1 - 0.0015 18.2 5.4 0.43 10.3 0.7 3.6 3 0 0 3 3 3 2 MFS_1 like family Pet127 PF08634.5 KIA75390.1 - 0.2 10.8 0.1 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Aldo_ket_red PF00248.16 KIA75391.1 - 1.6e-63 214.2 0.0 1.9e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KIA75392.1 - 6.4e-90 301.5 0.0 8.5e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MBOAT_2 PF13813.1 KIA75392.1 - 3e-24 84.9 0.5 8.3e-24 83.4 0.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family AMP-binding_C PF13193.1 KIA75392.1 - 4.1e-11 43.6 0.0 1e-10 42.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMN_dh PF01070.13 KIA75393.1 - 1.6e-117 392.3 0.0 1.8e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KIA75393.1 - 1.3e-05 24.5 1.0 2e-05 23.9 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KIA75393.1 - 3e-05 23.2 0.2 0.014 14.4 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KIA75393.1 - 5.7e-05 22.1 0.5 0.00011 21.1 0.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KIA75393.1 - 0.00023 20.2 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KIA75393.1 - 0.00086 18.6 0.1 0.14 11.4 0.0 3.0 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KIA75393.1 - 0.005 15.9 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 KIA75393.1 - 0.2 10.4 0.2 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Pyr_redox_2 PF07992.9 KIA75394.1 - 4.2e-13 49.6 0.0 8.8e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75394.1 - 0.0027 17.4 0.2 3.3 7.4 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KIA75394.1 - 0.0087 15.0 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KIA75394.1 - 0.018 13.9 0.2 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 KIA75394.1 - 0.024 14.6 0.2 0.071 13.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KIA75394.1 - 0.11 11.5 0.1 0.42 9.5 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.17 KIA75395.1 - 2.7e-23 82.2 0.0 2.5e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KIA75396.1 - 9.6e-08 31.2 2.4 1.5e-07 30.5 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75396.1 - 2.1e-07 30.7 11.3 4.4e-07 29.6 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 KIA75397.1 - 5e-89 298.8 35.3 5.8e-89 298.6 24.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TauD PF02668.11 KIA75398.1 - 1.2e-37 129.9 0.1 1.8e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KIA75398.1 - 0.026 15.0 0.1 2.5 8.6 0.0 2.8 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 KIA75399.1 - 1.3e-33 116.7 0.5 1.5e-33 116.5 0.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75399.1 - 5e-20 71.7 0.1 1.3e-19 70.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KIA75399.1 - 1.2e-11 44.6 0.0 6.5e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KIA75399.1 - 3.3e-06 27.4 0.0 4.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KIA75399.1 - 8.2e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 KIA75399.1 - 0.00068 18.5 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.5 KIA75399.1 - 0.0016 18.3 0.0 0.0069 16.2 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein PGAP1 PF07819.8 KIA75399.1 - 0.0018 17.9 0.1 0.0057 16.2 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 KIA75399.1 - 0.0041 16.7 0.1 0.0098 15.5 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase UPF0227 PF05728.7 KIA75399.1 - 0.0047 16.6 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 KIA75399.1 - 0.014 15.0 0.2 0.11 12.0 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KIA75399.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 KIA75399.1 - 0.032 13.6 0.9 1.7 8.0 0.1 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KIA75399.1 - 0.04 13.1 0.0 0.23 10.6 0.0 2.0 1 1 1 2 2 2 0 Dienelactone hydrolase family DUF915 PF06028.6 KIA75399.1 - 0.044 12.8 0.0 1.9 7.4 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KIA75399.1 - 0.045 13.3 0.3 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KIA75399.1 - 0.048 13.0 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PE-PPE PF08237.6 KIA75399.1 - 0.06 12.7 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 PE-PPE domain ApbA PF02558.11 KIA75400.1 - 3.1e-28 98.1 0.0 4.3e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KIA75400.1 - 2.2e-26 92.3 0.0 3.7e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 KIA75400.1 - 0.0025 17.6 0.8 0.017 14.9 0.1 2.4 3 0 0 3 3 3 1 ThiF family GFO_IDH_MocA PF01408.17 KIA75400.1 - 0.015 15.7 0.3 0.16 12.5 0.2 2.5 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 KIA75400.1 - 0.026 14.6 0.2 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 KIA75401.1 - 4.1e-51 174.4 0.0 6.6e-51 173.7 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 KIA75401.1 - 9.7e-17 60.8 0.0 1.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 KIA75401.1 - 6.5e-12 45.2 0.2 2.1e-11 43.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KIA75401.1 - 2.6e-09 36.4 0.8 4.4e-09 35.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KIA75401.1 - 2.4e-07 30.0 1.0 5.8e-07 28.7 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KIA75401.1 - 1.8e-06 27.2 0.4 3.6e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KIA75401.1 - 4.4e-06 26.9 0.1 2.4e-05 24.5 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KIA75401.1 - 1.2e-05 24.5 0.9 1.8e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KIA75401.1 - 1.6e-05 24.8 0.3 0.00014 21.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KIA75401.1 - 3.3e-05 23.1 0.4 5.1e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KIA75401.1 - 4.7e-05 22.4 0.2 0.00017 20.6 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KIA75401.1 - 0.00011 20.8 0.2 0.00019 20.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KIA75401.1 - 0.0016 17.3 1.0 0.0032 16.4 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KIA75401.1 - 0.072 13.5 0.5 0.17 12.3 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KIA75401.1 - 0.088 12.3 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.1 KIA75402.1 - 1.5e-23 83.8 0.1 2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75402.1 - 1.3e-14 54.4 0.5 7.1e-14 52.0 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase TauD PF02668.11 KIA75403.1 - 6.6e-32 111.1 0.0 9.8e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.20 KIA75404.1 - 2.1e-14 53.7 1.1 5e-14 52.5 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75404.1 - 4.2e-05 23.2 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KIA75404.1 - 0.00079 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KIA75404.1 - 0.0024 17.3 0.1 0.035 13.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KIA75404.1 - 0.029 13.2 0.2 0.56 9.0 0.0 2.6 2 1 0 2 2 2 0 Male sterility protein Methyltransf_2 PF00891.13 KIA75405.1 - 1.8e-27 96.0 0.3 3.9e-27 94.9 0.2 1.5 1 1 0 1 1 1 1 O-methyltransferase ADH_N PF08240.7 KIA75405.1 - 2.7e-11 43.1 0.0 1.2e-10 41.1 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KIA75405.1 - 1.5e-08 34.2 0.2 5.4e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 KIA75406.1 - 5.9e-49 166.3 0.0 7.4e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KIA75407.1 - 1.6e-18 66.6 25.2 1.6e-18 66.6 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75407.1 - 4.5e-07 28.8 4.8 4.5e-07 28.8 3.3 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KIA75407.1 - 3e-05 22.6 7.6 3e-05 22.6 5.3 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein DUF4149 PF13664.1 KIA75407.1 - 0.018 15.0 0.2 0.018 15.0 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) DUF202 PF02656.10 KIA75407.1 - 5.7 7.2 6.9 1.7 8.9 0.8 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF202) DUF3237 PF11578.3 KIA75408.1 - 8.4e-49 164.7 0.0 9.3e-49 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) p450 PF00067.17 KIA75409.1 - 4.5e-32 111.1 0.0 5.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dehydratase_LU PF02286.10 KIA75409.1 - 0.024 12.8 0.1 1.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Dehydratase large subunit FAD_binding_3 PF01494.14 KIA75410.1 - 1.4e-23 83.5 0.1 6e-23 81.4 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KIA75410.1 - 1.3e-05 24.4 0.6 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KIA75410.1 - 0.0003 19.8 3.2 0.027 13.3 0.6 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KIA75410.1 - 0.00049 20.0 0.5 0.0012 18.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KIA75410.1 - 0.00059 18.8 1.2 0.0039 16.1 0.8 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KIA75410.1 - 0.0086 16.4 1.8 0.036 14.4 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KIA75410.1 - 0.019 15.0 0.6 0.069 13.2 0.4 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA75410.1 - 0.031 13.1 0.5 0.051 12.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 KIA75410.1 - 0.15 10.8 0.0 4.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.19 KIA75412.1 - 3.1e-64 217.2 10.0 4.6e-64 216.6 4.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KIA75412.1 - 9.8e-24 83.7 23.2 2.4e-19 69.2 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1962 PF09227.5 KIA75412.1 - 0.15 12.1 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) UPF0075 PF03702.9 KIA75413.1 - 1.1e-12 47.6 0.1 5.6e-11 41.9 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0075) polyprenyl_synt PF00348.12 KIA75415.1 - 8.8e-52 175.5 0.0 1.4e-51 174.8 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KIA75415.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF3239 PF11580.3 KIA75415.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) UbiA PF01040.13 KIA75416.1 - 5.1e-30 104.5 15.3 6.3e-30 104.2 10.5 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 KIA75417.1 - 7.5e-37 126.9 0.0 1e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KIA75418.1 - 1.8e-25 89.7 0.1 4.6e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KIA75418.1 - 1.9e-06 27.0 0.1 0.003 16.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KIA75418.1 - 0.0002 21.2 0.1 0.0006 19.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KIA75418.1 - 0.0024 17.0 0.2 0.2 10.6 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KIA75418.1 - 0.0097 14.8 1.1 0.11 11.3 0.2 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KIA75418.1 - 0.028 13.0 0.1 4.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 KIA75418.1 - 0.045 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 KIA75418.1 - 0.054 12.3 0.0 3.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 KIA75418.1 - 0.14 12.0 0.1 0.39 10.5 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 KIA75419.1 - 3.8e-28 98.2 0.0 1.2e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.21 KIA75420.1 - 1.7e-65 221.0 1.2 4.7e-65 219.5 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75420.1 - 1.1e-36 125.2 0.8 2.5e-36 124.1 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KIA75420.1 - 2.7e-23 82.8 0.0 5.8e-22 78.4 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KIA75420.1 - 7.6e-18 64.5 0.7 1.7e-07 31.3 0.1 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 KIA75420.1 - 2.1e-13 50.1 0.0 6.3e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KIA75420.1 - 3.3e-08 32.8 0.9 1.5e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Oxidored_FMN PF00724.15 KIA75421.1 - 5.6e-94 314.9 0.0 6.4e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Trp_DMAT PF11991.3 KIA75423.1 - 1.4e-90 304.1 0.0 1.6e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase GFO_IDH_MocA PF01408.17 KIA75424.1 - 3.7e-13 50.0 0.5 7.2e-10 39.4 0.0 3.2 3 0 0 3 3 3 2 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KIA75424.1 - 5.1e-07 30.0 0.2 0.0019 18.4 0.0 3.1 3 0 0 3 3 3 2 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KIA75424.1 - 1.1e-05 24.9 0.1 0.00017 21.0 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA_C PF02894.12 KIA75424.1 - 2e-05 24.3 0.1 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans PF04082.13 KIA75425.1 - 3.3e-15 55.6 0.5 6.3e-15 54.7 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75425.1 - 1.1e-06 28.3 8.1 2e-06 27.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 KIA75426.1 - 4e-45 153.8 0.1 5.1e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 KIA75427.1 - 2.5e-29 102.1 33.3 3.5e-29 101.6 23.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KIA75428.1 - 1.9e-18 66.2 5.4 3.3e-18 65.4 3.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75428.1 - 3.9e-07 29.8 12.5 6.9e-07 29.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1963 PF09234.5 KIA75429.1 - 0.14 12.4 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Cellulase PF00150.13 KIA75430.1 - 2.5e-32 112.2 0.4 4e-32 111.5 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.13 KIA75430.1 - 0.076 12.3 0.1 1 8.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF295) INCENP_N PF12178.3 KIA75430.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Glyco_hydro_43 PF04616.9 KIA75431.1 - 2.6e-72 243.3 0.0 3.6e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 KIA75432.1 - 2.2e-72 244.0 32.8 2.6e-72 243.8 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75432.1 - 2.2e-23 82.5 52.8 6.1e-22 77.8 19.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KIA75432.1 - 1.6e-06 26.6 3.4 3e-06 25.7 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HlyC PF02794.11 KIA75432.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 RTX toxin acyltransferase family PLAC8 PF04749.12 KIA75433.1 - 7.7e-28 97.1 17.4 9.4e-28 96.8 12.1 1.1 1 0 0 1 1 1 1 PLAC8 family SUR7 PF06687.7 KIA75434.1 - 1.9e-40 138.7 12.0 2.3e-40 138.4 8.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family FAD_binding_4 PF01565.18 KIA75435.1 - 9.1e-24 83.5 1.3 1.6e-23 82.7 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75435.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like ADH_zinc_N PF00107.21 KIA75436.1 - 1.2e-09 37.7 0.8 5.7e-09 35.6 0.6 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KIA75436.1 - 1.1e-06 28.4 0.0 7.1e-06 25.7 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KIA75436.1 - 0.013 15.5 0.2 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Tannase PF07519.6 KIA75437.1 - 3.5e-107 359.0 0.3 4.2e-107 358.7 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase TraW_N PF12477.3 KIA75437.1 - 0.27 11.2 3.2 0.32 11.0 1.0 2.1 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Methyltransf_11 PF08241.7 KIA75438.1 - 3.5e-23 81.8 0.0 7.5e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75438.1 - 8.1e-22 77.4 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75438.1 - 4.6e-17 62.2 0.0 8.2e-17 61.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75438.1 - 1.2e-15 58.0 0.0 3.9e-15 56.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75438.1 - 1.3e-15 57.7 0.0 3.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75438.1 - 4.8e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75438.1 - 2.5e-13 49.6 0.0 3.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KIA75438.1 - 8.5e-12 45.1 0.0 2.3e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KIA75438.1 - 3.1e-08 33.1 0.0 5.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KIA75438.1 - 2.3e-05 23.7 0.0 0.0027 17.0 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PCMT PF01135.14 KIA75438.1 - 5.9e-05 22.6 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 KIA75438.1 - 0.00019 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 KIA75438.1 - 0.00024 20.1 0.0 0.0015 17.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 KIA75438.1 - 0.00074 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KIA75438.1 - 0.0027 17.4 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KIA75438.1 - 0.0036 16.6 0.0 0.013 14.8 0.0 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 KIA75438.1 - 0.0072 15.4 0.4 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.12 KIA75438.1 - 0.01 14.8 0.0 0.42 9.5 0.0 2.4 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family PrmA PF06325.8 KIA75438.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KIA75438.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 KIA75438.1 - 0.059 13.0 0.0 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.11 KIA75438.1 - 0.082 11.2 0.0 0.3 9.3 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyl_transf_1 PF00698.16 KIA75439.1 - 7.9e-68 229.1 0.0 1.5e-67 228.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KIA75439.1 - 3.1e-66 223.4 0.0 5.6e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75439.1 - 5.9e-61 205.2 0.0 2e-60 203.5 0.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KIA75439.1 - 4.6e-50 169.7 0.1 2.1e-49 167.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KIA75439.1 - 5e-48 163.7 0.0 8.1e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75439.1 - 2.8e-27 94.9 0.1 7e-27 93.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75439.1 - 4e-17 61.9 0.0 1.9e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KIA75439.1 - 3.4e-10 40.2 0.0 1.8e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75439.1 - 9.4e-08 31.7 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75439.1 - 1.2e-07 32.6 0.0 6.8e-07 30.2 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KIA75439.1 - 6.5e-05 23.4 0.0 0.00039 20.9 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75439.1 - 0.00017 21.3 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KIA75439.1 - 0.00018 21.2 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KIA75439.1 - 0.00069 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KIA75439.1 - 0.0027 17.7 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75439.1 - 0.0069 16.8 0.0 0.034 14.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KIA75439.1 - 0.01 14.5 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KIA75439.1 - 0.059 12.3 0.4 0.25 10.3 0.1 2.0 2 0 0 2 2 2 0 Thiolase, N-terminal domain HsbA PF12296.3 KIA75440.1 - 1e-22 80.3 0.5 1.4e-22 79.8 0.4 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A IspD PF01128.14 KIA75440.1 - 0.0023 17.5 0.2 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pyr_redox_3 PF13738.1 KIA75441.1 - 1.9e-25 90.1 0.0 3.7e-24 85.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KIA75441.1 - 8.4e-10 38.0 0.0 2.5e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KIA75441.1 - 6.4e-09 34.5 0.0 1.2e-07 30.3 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KIA75441.1 - 2.6e-05 24.2 0.0 9.5e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75441.1 - 0.032 13.9 0.0 3.1 7.5 0.0 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 KIA75443.1 - 3e-19 68.9 0.5 5.1e-19 68.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75443.1 - 2.4e-05 24.1 11.2 4.6e-05 23.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHY PF00360.15 KIA75444.1 - 8e-31 106.5 0.0 1.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KIA75444.1 - 4.7e-19 68.1 0.1 1.9e-18 66.1 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KIA75444.1 - 5.2e-17 61.8 0.0 1.5e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 KIA75444.1 - 2.9e-13 50.2 0.1 1.2e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 KIA75444.1 - 1.1e-11 44.5 0.1 4.4e-11 42.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KIA75444.1 - 1.4e-08 35.1 0.0 2.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 KIA75444.1 - 0.078 12.6 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase p450 PF00067.17 KIA75445.1 - 5.4e-73 246.0 0.0 7.7e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2233 PF09992.4 KIA75445.1 - 0.02 14.9 0.2 5.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2233) ComX PF05952.7 KIA75445.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX GMC_oxred_N PF00732.14 KIA75446.1 - 1.8e-55 188.1 0.0 2.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KIA75446.1 - 1.3e-38 132.5 0.1 2.4e-38 131.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KIA75446.1 - 1.7e-08 33.7 0.1 0.00017 20.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KIA75446.1 - 8.6e-07 28.1 0.6 0.00036 19.4 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KIA75446.1 - 2.2e-06 27.6 0.1 0.00027 20.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KIA75446.1 - 6.8e-05 21.9 0.3 0.00011 21.2 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KIA75446.1 - 8.5e-05 22.4 0.2 0.00022 21.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KIA75446.1 - 0.00018 21.6 0.0 0.29 11.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KIA75446.1 - 0.00035 19.7 0.3 0.0006 18.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KIA75446.1 - 0.0025 16.3 0.6 0.013 14.0 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KIA75446.1 - 0.036 12.9 0.6 0.96 8.2 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KIA75446.1 - 0.042 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KIA75446.1 - 0.098 11.2 0.3 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 KIA75446.1 - 0.18 11.8 0.4 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Zn_clus PF00172.13 KIA75447.1 - 3.8e-07 29.9 10.1 7.4e-07 28.9 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.13 KIA75448.1 - 1.4e-28 99.7 0.0 2.2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KIA75448.1 - 3.1e-20 72.3 0.0 4.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KIA75448.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KIA75448.1 - 0.022 14.7 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 KIA75448.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 KIA75448.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KIA75449.1 - 3.2e-36 124.7 28.6 4e-36 124.4 19.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KIA75449.1 - 0.011 15.5 2.8 0.031 14.0 2.0 1.8 1 0 0 1 1 1 0 MFS_1 like family YesK PF14150.1 KIA75449.1 - 0.014 15.4 1.1 0.014 15.4 0.7 4.1 4 1 1 5 5 5 0 YesK-like protein GMC_oxred_N PF00732.14 KIA75450.1 - 1.1e-59 201.9 0.0 1.5e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KIA75450.1 - 2.3e-31 109.0 0.4 9.2e-31 107.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KIA75450.1 - 0.00022 20.2 0.6 0.086 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KIA75450.1 - 0.0014 17.5 0.0 0.0034 16.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KIA75450.1 - 0.0073 16.3 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KIA75450.1 - 0.0095 14.8 0.0 0.021 13.7 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KIA75450.1 - 0.029 14.4 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KIA75450.1 - 0.058 12.4 0.2 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KIA75450.1 - 0.17 11.8 1.1 9.3 6.2 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Antimicrobial10 PF08105.6 KIA75450.1 - 0.29 10.7 1.9 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Metchnikowin family F-box PF00646.28 KIA75451.1 - 3.9e-05 23.1 0.5 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KIA75451.1 - 0.0064 16.1 1.3 0.0081 15.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like adh_short PF00106.20 KIA75452.1 - 2.3e-16 60.1 0.0 3.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75452.1 - 2.9e-08 33.5 0.0 4.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KIA75452.1 - 0.00015 20.7 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KIA75452.1 - 0.00035 20.4 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KIA75452.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MoCF_biosynth PF00994.19 KIA75452.1 - 0.036 13.4 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Probable molybdopterin binding domain Methyltransf_2 PF00891.13 KIA75453.1 - 1.1e-27 96.7 0.0 3.2e-27 95.2 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase HTH_20 PF12840.2 KIA75453.1 - 0.13 12.0 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Asp_Glu_race PF01177.17 KIA75454.1 - 8.6e-17 61.7 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase SARS_lipid_bind PF09399.5 KIA75454.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 SARS lipid binding protein MFS_1 PF07690.11 KIA75455.1 - 6e-42 143.6 46.9 6e-42 143.6 32.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KIA75456.1 - 3.7e-13 49.2 0.1 6.2e-07 28.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KIA75456.1 - 5.7e-06 25.4 1.3 0.034 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KIA75456.1 - 0.00054 18.9 0.1 0.0014 17.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KIA75456.1 - 0.0013 17.2 0.2 0.22 9.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KIA75456.1 - 0.0033 17.3 1.3 0.017 14.9 0.6 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KIA75456.1 - 0.041 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KIA75456.1 - 0.23 10.8 0.9 0.48 9.7 0.6 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 KIA75457.1 - 2.9e-30 105.2 0.0 4.2e-28 98.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.23 KIA75458.1 - 1.4e-248 824.1 0.0 6e-86 288.4 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KIA75458.1 - 2.4e-139 463.3 0.0 4.4e-38 130.8 0.0 5.7 6 0 0 6 6 6 5 Condensation domain PP-binding PF00550.20 KIA75458.1 - 9.4e-35 118.7 1.9 4.4e-13 49.2 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site DAHP_synth_2 PF01474.11 KIA75462.1 - 1.7e-192 639.6 0.0 2.2e-192 639.2 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family FAD_binding_4 PF01565.18 KIA75462.1 - 1.4e-20 73.1 0.7 5.3e-20 71.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain But2 PF09792.4 KIA75464.1 - 6.5e-60 201.0 3.2 1.4e-59 199.9 2.2 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Prefoldin_3 PF13758.1 KIA75465.1 - 1.9e-37 127.0 1.1 7.5e-37 125.0 0.8 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KIA75465.1 - 7.4e-20 71.7 2.7 7.4e-20 71.7 1.9 4.7 5 2 0 5 5 5 2 Domain of unknown function (DUF3835) DUF1730 PF08331.5 KIA75465.1 - 0.029 14.0 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) MAT1 PF06391.8 KIA75466.1 - 2.1e-35 122.1 12.8 2.7e-35 121.7 8.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KIA75466.1 - 0.00025 20.6 4.7 0.001 18.6 3.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KIA75466.1 - 0.00088 19.2 5.2 0.002 18.1 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KIA75466.1 - 0.0016 18.1 6.0 0.003 17.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KIA75466.1 - 0.0042 16.8 5.5 0.0089 15.8 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KIA75466.1 - 0.015 14.8 5.5 0.15 11.6 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KIA75466.1 - 0.016 14.9 8.9 0.2 11.4 6.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain VID27 PF08553.5 KIA75466.1 - 0.15 10.2 4.8 0.2 9.8 3.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NGP1NT PF08153.7 KIA75468.1 - 1.9e-47 160.4 0.0 2.9e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KIA75468.1 - 2.2e-19 69.5 0.1 2.3e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KIA75468.1 - 5.4e-05 22.5 0.0 0.00079 18.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KIA75468.1 - 0.00027 20.2 0.0 0.1 11.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 KIA75468.1 - 0.00046 20.0 0.1 0.32 10.8 0.0 3.4 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KIA75468.1 - 0.0027 17.1 0.0 0.51 9.7 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KIA75468.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KIA75468.1 - 0.11 13.0 0.1 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Pkinase PF00069.20 KIA75469.1 - 3.5e-41 141.0 0.0 3e-40 138.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KIA75469.1 - 1.1e-27 96.7 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KIA75469.1 - 0.00076 18.5 0.0 0.0021 17.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KIA75469.1 - 0.006 16.3 0.1 0.1 12.3 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KIA75469.1 - 0.0093 15.0 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KIA75469.1 - 0.22 10.2 0.0 0.64 8.7 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Rad50_zn_hook PF04423.9 KIA75469.1 - 2.1 7.8 4.7 0.9 9.0 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif NAD_binding_4 PF07993.7 KIA75471.1 - 1.1e-44 152.2 0.0 1.6e-42 145.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KIA75471.1 - 2.9e-30 105.0 0.2 6.5e-30 103.8 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KIA75471.1 - 9.8e-11 41.5 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_33 PF13671.1 KIA75471.1 - 1.3e-07 31.5 0.0 4.2e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain PP-binding PF00550.20 KIA75471.1 - 1.6e-06 28.3 0.3 4.3e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AAA_17 PF13207.1 KIA75471.1 - 7.8e-06 26.7 0.0 7.5e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 KIA75471.1 - 1.2e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase 3Beta_HSD PF01073.14 KIA75471.1 - 2e-05 23.4 0.0 6.8e-05 21.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KIA75471.1 - 5.2e-05 22.9 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KIA75471.1 - 6.4e-05 22.9 0.2 0.00035 20.5 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase AAA_18 PF13238.1 KIA75471.1 - 0.00017 21.8 0.0 0.0014 18.9 0.0 2.7 3 1 0 3 3 2 1 AAA domain SKI PF01202.17 KIA75471.1 - 0.00042 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase NAD_binding_10 PF13460.1 KIA75471.1 - 0.0012 18.8 0.2 0.11 12.4 0.1 3.5 3 1 0 3 3 3 1 NADH(P)-binding Zeta_toxin PF06414.7 KIA75471.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Polysacc_synt_2 PF02719.10 KIA75471.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SRPRB PF09439.5 KIA75471.1 - 0.062 12.5 0.0 5.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 KIA75471.1 - 0.067 12.7 0.3 0.41 10.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KIA75471.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Aldo_ket_red PF00248.16 KIA75472.1 - 4.5e-50 170.0 0.0 5.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 KIA75473.1 - 7.6e-22 77.4 0.0 1.2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75473.1 - 1e-05 25.3 10.4 1e-05 25.3 7.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KIA75475.1 - 6.2e-29 101.4 0.0 7.5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75475.1 - 1.9e-27 96.2 2.7 2.4e-27 95.9 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75475.1 - 6.9e-16 58.4 1.2 9.5e-16 57.9 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75475.1 - 0.0079 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alk_phosphatase PF00245.15 KIA75475.1 - 0.038 12.6 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase DUF3277 PF11681.3 KIA75475.1 - 0.042 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) ADH_N PF08240.7 KIA75476.1 - 4.1e-24 84.4 0.7 8.6e-24 83.4 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KIA75476.1 - 5.3e-17 61.5 0.5 8.2e-17 60.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CW_binding_2 PF04122.7 KIA75476.1 - 0.036 14.2 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 HAD_2 PF13419.1 KIA75477.1 - 2.9e-25 89.4 0.0 4.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KIA75477.1 - 9.6e-05 22.8 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KIA75477.1 - 0.00024 20.7 0.0 0.00067 19.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like PfkB PF00294.19 KIA75478.1 - 5.5e-30 104.5 0.4 1.8e-28 99.5 0.3 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MFS_1 PF07690.11 KIA75479.1 - 1.6e-41 142.1 46.2 1.6e-41 142.1 32.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75479.1 - 3.6e-11 42.3 12.1 3.6e-11 42.3 8.4 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter RTA1 PF04479.8 KIA75480.1 - 2.1e-21 76.4 5.9 3.8e-21 75.6 4.1 1.4 1 1 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 KIA75480.1 - 0.06 12.7 1.1 0.5 9.7 0.5 2.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase Zn_clus PF00172.13 KIA75481.1 - 2e-08 34.0 13.2 3.1e-08 33.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KIA75482.1 - 3.2e-11 42.5 1.7 3.2e-11 42.5 1.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75482.1 - 5.8e-06 26.1 15.3 1.3e-05 25.0 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPH3 PF03000.9 KIA75482.1 - 0.061 12.8 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 NPH3 family Pyr_redox_3 PF13738.1 KIA75483.1 - 1.6e-22 80.5 0.0 2.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KIA75483.1 - 1.8e-12 46.2 0.0 2.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KIA75483.1 - 1.4e-09 38.1 0.0 0.017 15.0 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KIA75483.1 - 7.9e-09 35.4 0.0 1.1e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KIA75483.1 - 3.9e-08 32.6 0.0 7.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KIA75483.1 - 0.00017 21.4 0.3 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KIA75483.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KIA75483.1 - 0.0024 18.2 0.1 0.32 11.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KIA75483.1 - 0.0034 17.3 1.1 0.13 12.3 0.0 3.6 4 1 0 4 4 4 1 TrkA-N domain FAD_binding_3 PF01494.14 KIA75483.1 - 0.015 14.3 0.1 3.1 6.7 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 KIA75483.1 - 0.038 14.0 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 KIA75483.1 - 0.082 13.0 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_Gly3P_dh_N PF01210.18 KIA75483.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 KIA75483.1 - 0.089 12.1 0.1 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KIA75483.1 - 0.11 12.7 0.0 9.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding DAO PF01266.19 KIA75483.1 - 0.13 11.1 0.7 36 3.1 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.11 KIA75483.1 - 0.16 11.4 0.2 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KIA75483.1 - 0.23 11.1 0.2 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 KIA75484.1 - 1.3e-44 152.2 0.0 1.7e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KIA75484.1 - 5.8e-12 45.1 0.0 8.7e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KIA75484.1 - 2e-06 27.5 0.1 3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KIA75484.1 - 0.0071 15.0 0.0 0.0098 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Lgl_C PF08596.5 KIA75485.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal 7TM_GPCR_Srd PF10317.4 KIA75485.1 - 0.82 8.5 13.6 0.55 9.1 0.1 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd p450 PF00067.17 KIA75486.1 - 9.6e-61 205.7 0.0 1.3e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RPE65 PF03055.10 KIA75487.1 - 1.1e-109 367.1 0.0 1.4e-109 366.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ATP_synt_I PF03899.10 KIA75488.1 - 9.9 6.3 13.2 0.058 13.5 2.1 2.5 2 2 0 2 2 2 0 ATP synthase I chain Zn_clus PF00172.13 KIA75489.1 - 8.2e-06 25.6 4.6 2.1e-05 24.3 3.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 KIA75490.1 - 2.3e-77 259.8 0.4 4.6e-77 258.9 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75490.1 - 8.3e-64 214.5 0.0 1.9e-63 213.4 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KIA75490.1 - 1.2e-53 182.4 0.1 2.1e-53 181.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KIA75490.1 - 5.4e-50 169.5 0.0 2.2e-49 167.5 0.0 2.2 2 0 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 KIA75490.1 - 1.5e-45 155.6 0.1 2.6e-45 154.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75490.1 - 1.2e-34 118.7 0.2 3.1e-34 117.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75490.1 - 1.2e-18 66.8 0.0 3.5e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA75490.1 - 1.4e-08 35.7 0.0 4.8e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KIA75490.1 - 4.3e-07 29.6 0.1 9.5e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KIA75490.1 - 4.7e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KIA75490.1 - 2.6e-05 24.5 0.0 6.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 KIA75490.1 - 0.00059 18.9 0.9 0.034 13.1 0.0 2.7 3 0 0 3 3 3 1 Saccharopine dehydrogenase Thiolase_N PF00108.18 KIA75490.1 - 0.0088 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 KIA75490.1 - 0.013 15.1 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ACP_syn_III PF08545.5 KIA75490.1 - 0.024 14.2 0.2 0.098 12.3 0.1 2.1 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.16 KIA75490.1 - 0.039 13.3 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75490.1 - 0.29 9.8 0.0 0.53 8.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M6 PF05547.6 KIA75490.1 - 1.7 6.6 0.0 2.7 5.9 0.0 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 MFS_1 PF07690.11 KIA75491.1 - 2.9e-28 98.6 53.9 3.3e-27 95.1 37.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3353 PF11833.3 KIA75491.1 - 5.5 6.4 11.1 0.19 11.1 0.4 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3353) HsbA PF12296.3 KIA75492.1 - 1.6e-23 82.9 5.2 2.2e-23 82.4 3.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FSH1 PF03959.8 KIA75493.1 - 2.1e-24 86.1 0.0 7.2e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KIA75493.1 - 0.00037 20.4 0.1 0.00067 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_zinc_N_2 PF13602.1 KIA75494.1 - 4.9e-21 75.9 0.1 9.3e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KIA75494.1 - 1.3e-15 57.1 0.0 3.5e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aa_trans PF01490.13 KIA75495.1 - 3.1e-41 141.2 10.0 3.4e-35 121.3 1.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 KIA75495.1 - 0.00018 21.2 0.2 0.026 14.2 0.4 2.4 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction SKG6 PF08693.5 KIA75495.1 - 0.00091 18.4 0.0 0.0031 16.7 0.0 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KIA75495.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AMP-binding PF00501.23 KIA75496.1 - 1.9e-79 267.0 0.1 2.5e-79 266.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KIA75496.1 - 9.9e-59 198.6 1.7 1.3e-30 106.3 0.0 3.4 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KIA75496.1 - 9.5e-05 22.5 0.0 0.0004 20.5 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75496.1 - 0.043 14.7 0.0 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain p450 PF00067.17 KIA75497.1 - 6.1e-57 193.1 0.0 7.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GLE1 PF07817.8 KIA75497.1 - 0.13 11.1 0.2 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 GLE1-like protein MFS_1 PF07690.11 KIA75498.1 - 6.9e-19 67.7 25.3 6.9e-19 67.7 17.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KIA75499.1 - 1.2e-66 224.4 0.1 1.4e-66 224.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LacI PF00356.16 KIA75499.1 - 0.098 12.2 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial regulatory proteins, lacI family Sulfate_transp PF00916.15 KIA75500.1 - 2e-06 27.0 4.8 2e-06 27.0 3.3 3.5 3 1 0 3 3 3 2 Sulfate transporter family PhyH PF05721.8 KIA75502.1 - 2.3e-42 145.4 0.0 2.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.13 KIA75503.1 - 3.5e-07 30.0 8.8 3.5e-07 30.0 6.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4521 PF15021.1 KIA75503.1 - 0.12 11.9 4.0 0.25 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) Paramyxo_C PF01692.13 KIA75503.1 - 0.12 11.9 1.3 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c DUF1117 PF06547.7 KIA75503.1 - 1.9 8.6 7.6 2.9 8.0 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) ketoacyl-synt PF00109.21 KIA75504.1 - 9.8e-62 208.7 1.0 2.7e-61 207.2 0.3 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KIA75504.1 - 5.1e-60 203.1 0.0 8.7e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KIA75504.1 - 9.3e-58 196.0 0.0 1.5e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KIA75504.1 - 5.1e-48 163.1 0.6 5.1e-48 163.1 0.4 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KIA75504.1 - 4.2e-39 134.1 4.3 8.5e-39 133.1 0.6 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75504.1 - 1.1e-37 128.4 0.2 7.8e-37 125.7 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75504.1 - 9.8e-15 54.2 0.0 2.7e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KIA75504.1 - 2.1e-08 33.8 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KIA75504.1 - 1.6e-07 32.2 0.0 6e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KIA75504.1 - 0.013 15.7 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site adh_short_C2 PF13561.1 KIA75505.1 - 2e-25 89.9 0.7 4.3e-25 88.8 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75505.1 - 8.8e-25 87.5 4.9 1.8e-24 86.5 3.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75505.1 - 6.8e-11 42.1 1.0 8.7e-11 41.8 0.7 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KIA75505.1 - 0.0002 20.3 0.4 0.00032 19.7 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KIA75505.1 - 0.0013 18.1 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75505.1 - 0.026 13.2 0.4 0.15 10.7 0.1 2.2 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 KIA75506.1 - 3.8e-78 263.0 0.0 4.8e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 KIA75507.1 - 1.3e-93 314.1 0.0 1.8e-93 313.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.20 KIA75507.1 - 3.1e-18 66.2 0.5 5.6e-18 65.4 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75507.1 - 9e-13 48.2 0.5 2e-12 47.1 0.4 1.5 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.6 KIA75508.1 - 0.00011 21.6 0.0 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Auxin_BP PF02041.11 KIA75508.1 - 0.0099 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Auxin binding protein adh_short PF00106.20 KIA75509.1 - 1.5e-24 86.8 0.1 2.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75509.1 - 5e-10 39.3 0.0 1.5e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KIA75509.1 - 4.1e-09 36.5 0.0 5.8e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KIA75509.1 - 0.00035 20.6 0.1 0.00053 20.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_3 PF01494.14 KIA75510.1 - 1.6e-17 63.6 1.2 2.7e-16 59.5 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KIA75510.1 - 7.7e-05 21.7 2.0 0.065 12.1 0.2 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KIA75510.1 - 8.9e-05 22.4 0.2 0.00045 20.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KIA75510.1 - 0.00032 19.4 0.3 0.00095 17.9 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 KIA75510.1 - 0.013 15.8 1.5 0.36 11.2 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KIA75510.1 - 0.08 11.8 3.5 0.056 12.3 0.6 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KIA75510.1 - 0.13 12.1 0.6 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA75510.1 - 0.55 9.0 3.6 0.27 10.0 0.8 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_4 PF01565.18 KIA75511.1 - 9.3e-24 83.4 0.6 1.8e-23 82.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75511.1 - 0.00015 21.6 0.1 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.14 KIA75512.1 - 1.6e-69 234.6 0.0 1.9e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KIA75512.1 - 4.4e-11 42.3 0.2 3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KIA75512.1 - 6.8e-06 26.2 0.2 0.00011 22.3 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KIA75512.1 - 7.2e-05 23.1 0.1 0.0038 17.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KIA75512.1 - 0.00013 21.9 0.0 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KIA75512.1 - 0.0014 18.5 0.0 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA75512.1 - 0.0021 16.9 0.0 0.091 11.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KIA75512.1 - 0.0039 15.7 0.0 0.15 10.5 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 KIA75512.1 - 0.0072 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KIA75512.1 - 0.046 12.6 0.2 0.089 11.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 KIA75512.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KIA75512.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_43 PF04616.9 KIA75513.1 - 1.2e-10 40.9 4.3 4.9e-09 35.6 1.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 APH PF01636.18 KIA75514.1 - 0.006 16.3 0.0 0.008 15.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.17 KIA75514.1 - 0.046 12.2 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 YidC_periplas PF14849.1 KIA75514.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 YidC periplasmic domain Ank_2 PF12796.2 KIA75517.1 - 8.1e-51 170.3 0.3 9.5e-16 57.9 0.0 9.4 6 2 4 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KIA75517.1 - 3.7e-39 132.4 5.6 5.5e-10 39.4 0.0 10.6 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KIA75517.1 - 3.9e-31 106.3 10.2 0.0017 18.5 0.0 11.3 11 1 2 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.25 KIA75517.1 - 1.2e-29 100.6 18.2 5.8e-05 22.7 0.0 13.2 14 0 0 14 14 14 7 Ankyrin repeat Ank_3 PF13606.1 KIA75517.1 - 4.2e-27 91.4 11.0 0.00086 19.3 0.0 12.3 13 0 0 13 13 13 5 Ankyrin repeat MFS_1 PF07690.11 KIA75518.1 - 2.5e-33 115.2 27.6 2.5e-33 115.2 19.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KIA75518.1 - 4 7.5 10.5 0.29 11.2 0.2 3.4 4 1 0 4 4 4 0 NfeD-like C-terminal, partner-binding PP2C PF00481.16 KIA75519.1 - 1.2e-37 129.6 0.0 2.4e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KIA75519.1 - 0.038 13.6 0.1 1.1 8.9 0.0 3.1 4 0 0 4 4 4 0 Stage II sporulation protein E (SpoIIE) DUF4298 PF14131.1 KIA75519.1 - 0.13 12.1 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) SUKH-4 PF14435.1 KIA75521.1 - 1.2e-05 25.1 0.3 0.036 13.7 0.0 2.2 2 0 0 2 2 2 2 SUKH-4 immunity protein F-box-like PF12937.2 KIA75521.1 - 0.00042 19.9 0.1 0.00074 19.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF2201_N PF13203.1 KIA75521.1 - 0.073 12.2 0.9 0.1 11.7 0.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 KIA75521.1 - 1.5 6.7 9.0 2 6.3 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 KIA75521.1 - 2 8.2 6.8 3.3 7.5 4.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 KIA75521.1 - 2.8 6.3 9.9 3.8 5.8 6.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KIA75521.1 - 3.3 7.0 10.3 4.9 6.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) adh_short PF00106.20 KIA75522.1 - 1.8e-24 86.5 0.2 1.1e-22 80.6 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75522.1 - 4.6e-17 62.5 0.6 1.2e-16 61.2 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75522.1 - 4.3e-10 39.5 0.4 3.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KIA75522.1 - 0.00011 22.3 1.0 0.00037 20.5 0.7 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KIA75522.1 - 0.00077 18.4 0.1 0.0012 17.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AA_kinase PF00696.23 KIA75522.1 - 0.0033 16.9 0.2 0.16 11.4 0.1 2.0 2 0 0 2 2 2 1 Amino acid kinase family ADH_zinc_N PF00107.21 KIA75522.1 - 0.0035 16.8 0.1 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KIA75522.1 - 0.012 15.1 0.8 0.031 13.7 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KIA75522.1 - 0.012 14.7 0.1 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KIA75522.1 - 0.067 13.1 0.2 0.19 11.7 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding SKI PF01202.17 KIA75522.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase F420_oxidored PF03807.12 KIA75522.1 - 0.081 13.3 0.6 0.24 11.8 0.4 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 KIA75522.1 - 0.085 13.2 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3822 PF12864.2 KIA75522.1 - 0.11 11.7 0.3 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) NAD_binding_7 PF13241.1 KIA75522.1 - 0.11 12.7 0.1 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NIF3 PF01784.13 KIA75522.1 - 0.34 10.4 2.2 0.78 9.2 0.4 2.0 1 1 1 2 2 2 0 NIF3 (NGG1p interacting factor 3) Trp_DMAT PF11991.3 KIA75523.1 - 1.5e-80 271.1 0.0 1.7e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Melibiase PF02065.13 KIA75524.1 - 7.5e-158 525.3 0.0 9.2e-158 525.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KIA75524.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 MFS_1 PF07690.11 KIA75525.1 - 1.5e-16 60.0 70.9 3.8e-15 55.4 44.0 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ABC_membrane PF00664.18 KIA75526.1 - 6.3e-74 248.8 22.6 3.8e-45 154.4 3.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KIA75526.1 - 4.2e-66 221.4 0.1 1.2e-32 113.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KIA75526.1 - 4.2e-15 55.5 4.5 6.2e-06 25.6 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KIA75526.1 - 2.8e-09 37.3 1.3 0.021 14.7 0.1 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KIA75526.1 - 4.8e-09 35.6 0.2 0.0028 17.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KIA75526.1 - 2e-08 34.4 2.7 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KIA75526.1 - 2.2e-07 31.7 0.1 0.0079 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KIA75526.1 - 5.8e-07 29.7 1.7 0.16 12.1 0.1 4.4 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KIA75526.1 - 8.3e-06 25.0 0.0 0.009 15.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KIA75526.1 - 9.8e-06 25.2 0.4 0.21 11.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KIA75526.1 - 1e-05 25.0 0.9 0.3 10.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 KIA75526.1 - 2.1e-05 23.3 2.9 0.00093 17.8 0.0 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class DUF87 PF01935.12 KIA75526.1 - 3e-05 23.9 0.2 0.0046 16.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KIA75526.1 - 0.00042 20.6 0.1 0.63 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KIA75526.1 - 0.00066 19.5 0.3 1.8 8.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KIA75526.1 - 0.00084 18.8 0.4 0.27 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain APS_kinase PF01583.15 KIA75526.1 - 0.00089 18.9 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.1 KIA75526.1 - 0.00093 19.5 3.6 0.78 10.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KIA75526.1 - 0.00098 19.3 0.6 6.6 6.9 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KIA75526.1 - 0.001 18.5 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 KIA75526.1 - 0.0011 18.2 0.0 0.14 11.3 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.1 KIA75526.1 - 0.0011 18.7 0.2 2.3 8.1 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KIA75526.1 - 0.0038 15.8 0.0 1.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Zeta_toxin PF06414.7 KIA75526.1 - 0.005 15.9 0.1 0.62 9.1 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 KIA75526.1 - 0.011 15.4 0.0 4.5 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KIA75526.1 - 0.018 14.9 0.0 4.4 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 KIA75526.1 - 0.046 13.6 0.2 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase KdpD PF02702.12 KIA75526.1 - 0.059 12.4 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain MobB PF03205.9 KIA75526.1 - 0.093 12.4 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AMP-binding PF00501.23 KIA75527.1 - 2.8e-84 282.9 0.0 1.3e-77 260.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KIA75527.1 - 3.2e-71 239.6 0.1 5.8e-37 127.1 0.0 2.8 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KIA75527.1 - 4.4e-25 87.7 0.2 4.1e-11 42.9 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75527.1 - 1.5e-09 38.6 1.0 0.00027 21.8 0.0 3.6 2 1 1 3 3 3 2 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 KIA75528.1 - 4.4e-14 52.2 0.6 8.8e-05 21.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KIA75528.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KIA75528.1 - 0.0037 16.2 1.6 0.0062 15.4 0.4 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KIA75528.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lactamase_B PF00753.22 KIA75529.1 - 2e-21 76.5 0.7 2.9e-21 76.0 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KIA75529.1 - 1.5e-05 24.6 0.1 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KIA75529.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.21 KIA75530.1 - 2.6e-72 243.3 0.2 4.2e-72 242.6 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75530.1 - 5.9e-45 153.9 0.0 9.8e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA75530.1 - 2.6e-32 111.1 1.3 6.9e-32 109.8 0.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KIA75530.1 - 8e-13 48.4 0.1 2e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA75530.1 - 3.1e-05 23.1 0.0 5.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KIA75531.1 - 1.1e-23 83.0 0.8 2.3e-23 82.0 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KIA75531.1 - 2.5e-23 82.0 0.2 6.7e-23 80.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KIA75531.1 - 7.3e-06 25.5 0.0 2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KIA75531.1 - 2e-05 25.4 0.0 3.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KIA75531.1 - 0.00012 22.2 0.1 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KIA75531.1 - 0.0007 18.7 0.1 0.00086 18.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KIA75531.1 - 0.012 15.1 0.1 0.042 13.4 0.1 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KIA75531.1 - 0.033 14.5 0.2 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KIA75531.1 - 0.035 13.9 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KIA75531.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase MARVEL PF01284.18 KIA75532.1 - 0.0003 20.6 12.5 0.00072 19.3 8.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 KIA75532.1 - 0.13 11.7 0.1 0.13 11.7 0.0 2.3 1 1 1 2 2 2 0 SUR7/PalI family Claudin_2 PF13903.1 KIA75532.1 - 3.7 7.1 9.8 16 5.1 5.2 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3498 PF12004.3 KIA75533.1 - 0.067 12.3 6.2 0.11 11.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) UvdE PF03851.9 KIA75534.1 - 2.8e-111 370.9 0.0 4.1e-111 370.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.4 KIA75534.1 - 3.9e-31 106.9 0.0 9.3e-31 105.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 KIA75534.1 - 0.018 15.1 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain AMP-binding PF00501.23 KIA75535.1 - 4.5e-218 723.6 0.0 3.6e-74 249.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KIA75535.1 - 5.3e-152 504.8 0.0 2.2e-35 121.9 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KIA75535.1 - 5.5e-48 161.0 5.0 3.4e-10 40.0 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75535.1 - 2.7e-20 73.0 0.3 2.4e-09 38.0 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KIA75535.1 - 0.028 14.7 0.3 0.25 11.6 0.2 2.8 3 0 0 3 3 3 0 HxxPF-repeated domain AMP-binding PF00501.23 KIA75536.1 - 3.7e-289 957.8 0.3 1.5e-87 293.7 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KIA75536.1 - 4.1e-239 790.9 0.0 3.6e-47 160.6 0.0 9.9 8 2 0 8 8 8 7 Condensation domain PP-binding PF00550.20 KIA75536.1 - 5.1e-44 148.3 4.5 2.4e-10 40.5 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75536.1 - 1e-12 48.7 0.1 0.0012 19.6 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain SBP_bac_5 PF00496.17 KIA75536.1 - 0.0043 15.9 0.0 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Transferase PF02458.10 KIA75536.1 - 0.0087 14.5 0.0 1.7 7.0 0.0 2.6 3 0 0 3 3 3 2 Transferase family ABC_tran PF00005.22 KIA75537.1 - 3.9e-44 150.2 0.0 6.5e-25 88.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KIA75537.1 - 2.6e-30 105.7 28.8 8.4e-24 84.4 6.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KIA75537.1 - 3.5e-10 40.3 1.6 0.0017 18.3 0.1 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KIA75537.1 - 1.4e-08 34.2 5.8 0.0054 15.9 0.1 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KIA75537.1 - 8e-06 26.0 1.3 0.13 12.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KIA75537.1 - 9.3e-06 25.7 1.7 0.06 13.3 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KIA75537.1 - 1.1e-05 24.9 0.3 0.055 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KIA75537.1 - 7.5e-05 23.1 0.7 0.1 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KIA75537.1 - 0.00062 18.9 1.8 0.1 11.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KIA75537.1 - 0.0012 18.2 1.8 0.46 10.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KIA75537.1 - 0.0015 18.2 1.2 0.15 11.7 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KIA75537.1 - 0.0016 18.3 0.0 0.083 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KIA75537.1 - 0.0022 17.8 0.1 1.3 9.0 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KIA75537.1 - 0.0025 17.3 5.3 0.29 10.5 0.3 2.9 2 1 1 3 3 3 2 AAA-like domain AAA PF00004.24 KIA75537.1 - 0.003 17.7 0.1 6.7 6.9 0.1 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KIA75537.1 - 0.0038 17.7 0.4 0.92 10.0 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 KIA75537.1 - 0.0047 17.7 0.1 7.1 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KIA75537.1 - 0.0055 16.8 0.4 2.1 8.5 0.0 3.2 3 0 0 3 3 3 1 RNA helicase T2SE PF00437.15 KIA75537.1 - 0.007 15.2 0.0 2 7.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Pox_A32 PF04665.7 KIA75537.1 - 0.009 15.3 0.8 2.3 7.4 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KIA75537.1 - 0.0097 15.3 0.2 2.1 7.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 KIA75537.1 - 0.01 15.4 0.3 3.8 7.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KIA75537.1 - 0.014 15.0 1.0 4.2 7.0 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KIA75537.1 - 0.017 15.0 0.1 8.7 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KIA75537.1 - 0.022 13.8 0.4 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 KIA75537.1 - 0.026 14.2 0.4 2.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_5 PF07728.9 KIA75537.1 - 0.059 13.1 0.9 13 5.4 0.1 3.7 4 1 1 5 5 4 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KIA75537.1 - 0.061 12.4 0.1 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 KIA75537.1 - 0.094 12.5 2.0 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 KIA75537.1 - 0.12 11.2 1.1 4.9 5.9 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain Guanylate_kin PF00625.16 KIA75537.1 - 0.18 11.2 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.14 KIA75537.1 - 0.18 11.2 2.8 6.6 6.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KIA75537.1 - 0.2 11.2 0.2 20 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KIA75537.1 - 0.25 11.6 0.9 27 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KIA75537.1 - 0.35 10.3 1.7 5.2 6.5 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.4 KIA75537.1 - 0.46 9.4 0.4 14 4.5 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.11 KIA75539.1 - 6.1e-36 123.8 44.6 6.1e-36 123.8 30.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 KIA75540.1 - 3.1e-08 33.3 0.5 4.7e-08 32.7 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KIA75540.1 - 3.4e-08 33.2 0.3 9.5e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KIA75541.1 - 2.9e-17 62.3 0.9 6e-17 61.3 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75541.1 - 5.4e-09 35.8 15.2 9.7e-09 34.9 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leptin PF02024.10 KIA75541.1 - 0.043 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Leptin MFS_1 PF07690.11 KIA75542.1 - 2.7e-36 125.0 30.8 2.7e-36 125.0 21.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KIA75542.1 - 0.54 10.6 4.0 0.16 12.3 0.2 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) VirB8 PF04335.8 KIA75542.1 - 2.5 7.6 4.4 2 7.9 0.2 2.5 2 1 0 2 2 2 0 VirB8 protein AMP-binding PF00501.23 KIA75543.1 - 9.5e-63 212.0 0.0 1.2e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KIA75543.1 - 8.4e-14 52.2 0.1 1.9e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KIA75544.1 - 2.3e-21 75.7 0.0 5.6e-15 54.7 0.0 2.4 2 1 0 2 2 2 2 Transferase family ketoacyl-synt PF00109.21 KIA75545.1 - 2e-73 247.0 0.1 3.3e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75545.1 - 3.5e-57 194.1 0.0 6.5e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KIA75545.1 - 2.5e-55 186.9 0.0 9e-55 185.1 0.0 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KIA75545.1 - 1e-49 169.3 0.0 2e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KIA75545.1 - 3e-40 137.8 0.1 1.1e-39 136.0 0.1 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75545.1 - 3.5e-37 126.8 0.8 1.4e-36 124.9 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75545.1 - 1.3e-19 70.0 0.0 7.2e-19 67.6 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KIA75545.1 - 2.5e-18 66.3 0.0 1.2e-17 64.1 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75545.1 - 6.6e-15 56.1 0.0 1.8e-13 51.5 0.0 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75545.1 - 2.3e-14 53.4 0.0 5.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75545.1 - 7.6e-09 35.9 0.0 5.9e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75545.1 - 9.2e-09 35.8 0.0 4.2e-08 33.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75545.1 - 2.1e-08 33.9 0.0 5.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75545.1 - 2.5e-08 33.3 0.0 4.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KIA75545.1 - 7.1e-06 26.2 0.1 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KIA75545.1 - 7.7e-05 22.7 0.0 0.00043 20.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75545.1 - 0.0017 18.6 0.0 0.0072 16.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KIA75545.1 - 0.0018 17.9 0.1 0.0067 16.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PCMT PF01135.14 KIA75545.1 - 0.0034 16.9 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KIA75545.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 KIA75545.1 - 0.042 14.6 0.0 0.33 11.7 0.0 2.6 2 0 0 2 2 1 0 Methyltransferase domain zf-C2H2 PF00096.21 KIA75546.1 - 3.5e-06 27.0 5.7 0.0057 16.9 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KIA75546.1 - 0.00049 20.2 1.2 0.0038 17.4 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KIA75546.1 - 0.04 14.2 6.8 0.44 10.9 1.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger Plasmod_MYXSPDY PF07981.6 KIA75546.1 - 0.056 13.1 3.1 0.056 13.1 2.1 2.7 3 1 0 3 3 3 0 Plasmodium repeat_MYXSPDY zf-C2H2_6 PF13912.1 KIA75546.1 - 0.25 11.3 3.2 0.61 10.0 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 KIA75546.1 - 1.9 8.8 7.3 0.29 11.4 2.3 1.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain AMP-binding PF00501.23 KIA75547.1 - 0 1355.0 3.7 1.5e-89 300.3 0.1 6.8 6 1 0 6 6 6 5 AMP-binding enzyme Condensation PF00668.15 KIA75547.1 - 2.3e-279 923.0 0.0 6e-45 153.3 0.0 9.2 9 0 0 9 9 9 8 Condensation domain PP-binding PF00550.20 KIA75547.1 - 2.5e-64 213.4 0.6 4.3e-10 39.6 0.0 7.6 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75547.1 - 5.7e-25 88.0 0.1 0.00019 22.2 0.0 6.2 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KIA75547.1 - 2.4e-05 24.5 0.2 1.6 9.0 0.0 4.1 3 0 0 3 3 3 2 HxxPF-repeated domain Transposase_31 PF04754.7 KIA75547.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF3243 PF11588.3 KIA75547.1 - 0.18 11.8 0.1 5.9 6.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) AATase PF07247.7 KIA75547.1 - 5.8 5.3 0.5 2.5e+02 -0.1 0.0 3.4 5 0 0 5 5 5 0 Alcohol acetyltransferase HAD_2 PF13419.1 KIA75548.1 - 3.1e-31 108.9 0.0 4.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KIA75548.1 - 0.076 13.4 0.0 1 9.7 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peroxidase_2 PF01328.12 KIA75549.1 - 1.1e-18 66.9 0.4 5.9e-12 44.8 0.0 2.7 2 1 0 2 2 2 2 Peroxidase, family 2 HET PF06985.6 KIA75550.1 - 0.00045 20.4 1.2 0.00082 19.5 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 KIA75551.1 - 3e-17 62.6 0.0 3.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KIA75551.1 - 0.00042 19.4 0.0 0.0006 18.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 KIA75551.1 - 0.013 15.3 0.0 0.37 10.5 0.0 2.7 3 0 0 3 3 3 0 ThiF family ApbA PF02558.11 KIA75551.1 - 0.038 13.4 0.1 0.096 12.1 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.1 KIA75551.1 - 0.044 12.7 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KIA75551.1 - 0.066 13.3 0.0 7.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KIA75551.1 - 0.082 12.9 0.2 1.2 9.1 0.1 2.7 1 1 0 1 1 1 0 NADH(P)-binding CBM_5_12 PF02839.9 KIA75551.1 - 0.14 11.7 0.8 0.36 10.4 0.5 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain Sugar_tr PF00083.19 KIA75552.1 - 3.3e-65 220.4 28.2 3.9e-65 220.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75552.1 - 3.2e-18 65.5 35.7 1.6e-09 36.9 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KIA75553.1 - 2.7e-45 154.7 0.0 1.9e-44 151.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 FA_hydroxylase PF04116.8 KIA75554.1 - 1.8e-16 60.5 10.5 1.8e-16 60.5 7.3 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF89 PF01937.14 KIA75554.1 - 0.052 12.3 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 PIG-L PF02585.12 KIA75556.1 - 1.3e-17 64.4 0.0 3.4e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_16 PF00722.16 KIA75557.1 - 2.2e-14 53.1 2.1 1.7e-13 50.2 1.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 E1-E2_ATPase PF00122.15 KIA75559.1 - 8.9e-60 201.5 0.2 1.6e-59 200.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KIA75559.1 - 7.2e-40 136.4 14.2 6.2e-35 120.3 1.0 3.5 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KIA75559.1 - 1.1e-30 107.6 0.0 3.5e-30 106.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KIA75559.1 - 3.3e-19 68.6 0.0 6.6e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KIA75559.1 - 2.5e-17 63.6 0.0 6.4e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KIA75559.1 - 2e-10 39.9 0.2 1.6e-08 33.8 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KIA75559.1 - 9.5e-07 28.6 0.0 0.0067 16.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 KIA75560.1 - 8.6e-75 247.1 3.9 4.8e-22 78.0 0.0 7.2 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75560.1 - 3.6e-68 222.1 20.5 6.3e-09 35.2 0.0 13.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 KIA75560.1 - 2.4e-49 164.2 16.1 7.2e-12 45.1 0.1 10.2 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75560.1 - 1.6e-48 157.8 4.9 1.5e-05 24.7 0.0 13.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KIA75560.1 - 3.8e-45 151.4 10.8 8.7e-10 38.8 0.0 9.9 3 2 7 11 11 11 10 Ankyrin repeats (many copies) NACHT PF05729.7 KIA75560.1 - 5.3e-08 32.7 0.0 1.8e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Amidohydro_4 PF13147.1 KIA75561.1 - 3.5e-22 79.7 0.1 4.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KIA75561.1 - 6.2e-15 54.7 0.8 1.9e-14 53.2 0.6 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KIA75561.1 - 2.2e-14 53.8 0.0 5.1e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 KIA75561.1 - 0.00013 22.0 1.1 0.00026 21.0 0.5 1.7 1 1 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.6 KIA75561.1 - 0.00013 21.2 0.0 0.035 13.3 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family DUF3425 PF11905.3 KIA75562.1 - 2.6e-17 62.9 0.0 5.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KIA75562.1 - 0.0012 18.7 8.0 0.002 18.0 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor NmrA PF05368.8 KIA75563.1 - 7e-41 140.0 0.0 1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KIA75563.1 - 6e-11 42.6 0.1 1.7e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KIA75563.1 - 3.8e-05 22.5 0.0 5.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KIA75563.1 - 0.00037 19.9 0.1 0.0046 16.4 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KIA75563.1 - 0.0006 19.7 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 KIA75563.1 - 0.0065 16.7 0.1 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KIA75563.1 - 0.017 15.0 0.3 0.03 14.2 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KIA75563.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.13 KIA75564.1 - 0.00045 20.0 6.4 0.0012 18.7 4.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KIA75565.1 - 2.3e-39 135.1 50.1 6.7e-38 130.3 33.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KIA75565.1 - 1.7e-10 39.7 23.6 2.4e-10 39.2 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.2 KIA75567.1 - 1.8e-48 162.8 0.4 1.1e-12 48.1 0.0 8.2 4 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75567.1 - 1.4e-37 125.6 17.1 1.6e-05 24.4 0.0 12.5 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.1 KIA75567.1 - 1.5e-30 102.1 3.1 0.022 14.9 0.0 12.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 KIA75567.1 - 1.4e-27 95.5 4.0 0.0004 20.8 0.0 9.5 4 2 7 11 11 11 8 Ankyrin repeats (many copies) Pkinase PF00069.20 KIA75567.1 - 1.9e-26 92.8 0.0 3.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 KIA75567.1 - 3e-23 81.2 7.3 0.0012 19.0 0.0 10.0 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KIA75567.1 - 3.6e-19 68.8 0.0 5.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.7 KIA75567.1 - 0.11 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Sel1 repeat p450 PF00067.17 KIA75568.1 - 2.2e-59 201.2 0.0 3.1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prenyltransf PF01255.14 KIA75570.1 - 4.5e-69 231.9 0.0 5.8e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Abhydrolase_6 PF12697.2 KIA75571.1 - 6.8e-07 29.4 0.4 1.3e-06 28.4 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75571.1 - 6.8e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KIA75571.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KIA75571.1 - 0.00041 19.7 0.0 0.00095 18.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KIA75571.1 - 0.0018 17.9 0.1 0.0058 16.2 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 KIA75571.1 - 0.013 14.9 0.6 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 KIA75571.1 - 0.016 14.7 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KIA75571.1 - 0.028 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KIA75571.1 - 0.13 12.4 0.3 0.33 11.1 0.2 1.6 1 1 0 1 1 1 0 Thioesterase domain PNP_UDP_1 PF01048.15 KIA75572.1 - 6.1e-11 41.7 0.1 1.2e-10 40.8 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Herpes_US9 PF06072.6 KIA75572.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Strep_his_triad PF04270.8 KIA75573.1 - 1.4 8.6 9.1 74 3.1 0.0 4.5 4 0 0 4 4 4 0 Streptococcal histidine triad protein DUF4644 PF15486.1 KIA75573.1 - 6 6.8 15.4 0.81 9.6 0.6 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4644) p450 PF00067.17 KIA75574.1 - 4.9e-66 223.1 0.0 6.7e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.23 KIA75575.1 - 9.3e-23 79.8 0.0 1.1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.19 KIA75576.1 - 2.5e-86 290.0 17.9 2.8e-86 289.8 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75576.1 - 8.9e-17 60.8 35.7 3.4e-11 42.4 8.7 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KIA75576.1 - 3.2e-05 23.8 3.2 0.097 12.7 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 KIA75577.1 - 5.3e-17 61.5 1.0 2e-11 43.1 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter ADH_zinc_N PF00107.21 KIA75577.1 - 1.3e-08 34.4 0.0 3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Na_Pi_cotrans PF02690.10 KIA75577.1 - 0.061 13.0 1.1 0.12 12.0 0.7 1.4 1 0 0 1 1 1 0 Na+/Pi-cotransporter Acyl_transf_1 PF00698.16 KIA75578.1 - 2.3e-62 211.1 0.0 3.8e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KIA75578.1 - 3.5e-60 203.6 0.1 7e-60 202.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75578.1 - 4.4e-55 186.1 0.7 1.1e-54 184.9 0.5 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KIA75578.1 - 1.6e-49 168.6 0.0 2.8e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KIA75578.1 - 1.5e-40 138.8 0.2 4.1e-40 137.4 0.2 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75578.1 - 3.5e-29 101.0 0.0 1.3e-28 99.2 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KIA75578.1 - 6e-18 65.1 0.0 2e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KIA75578.1 - 1e-13 50.9 0.1 3.8e-13 49.1 0.0 1.9 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75578.1 - 1.1e-13 51.2 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75578.1 - 1.7e-07 31.7 0.0 9.8e-07 29.3 0.0 2.4 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75578.1 - 2.1e-07 30.6 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75578.1 - 7e-07 29.6 0.0 2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75578.1 - 9.1e-07 29.8 0.1 9.1e-06 26.5 0.0 2.8 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KIA75578.1 - 5e-06 25.6 0.8 1.1e-05 24.6 0.6 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KIA75578.1 - 5.1e-06 26.6 0.0 2e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KIA75578.1 - 0.0099 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KIA75578.1 - 0.25 10.7 0.0 1.1 8.6 0.0 2.0 2 1 0 2 2 2 0 Putative methyltransferase DREV PF05219.7 KIA75578.1 - 0.29 9.9 0.0 0.59 8.9 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KIA75578.1 - 0.4 9.6 0.0 0.74 8.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Transferase PF02458.10 KIA75579.1 - 7e-12 44.5 0.0 2.5e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Transferase family PNP_UDP_1 PF01048.15 KIA75580.1 - 6.6e-13 48.1 1.0 1.6e-12 46.8 0.7 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KIA75580.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KIA75580.1 - 5.5e-07 29.7 0.1 4e-06 26.9 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KIA75580.1 - 3.5e-05 24.0 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KIA75580.1 - 7.6e-05 22.8 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KIA75580.1 - 0.0013 19.0 0.2 0.0042 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KIA75580.1 - 0.058 12.7 0.9 1.2 8.5 0.6 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KIA75580.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 KIA75580.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 KIA75580.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit adh_short PF00106.20 KIA75581.1 - 3.6e-15 56.2 0.1 5.7e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75581.1 - 7.3e-07 29.0 0.1 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75581.1 - 0.00024 20.6 0.0 0.00082 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KIA75581.1 - 0.0026 17.7 0.1 0.012 15.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding EF1_GNE PF00736.14 KIA75582.1 - 2.8e-27 94.2 2.1 4.6e-27 93.5 1.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KIA75582.1 - 1e-10 41.5 11.2 1e-10 41.5 7.7 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 KIA75582.1 - 0.013 15.4 0.5 0.041 13.8 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KIA75582.1 - 0.089 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.18 KIA75583.1 - 8.1e-24 83.6 1.6 1.7e-23 82.6 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75583.1 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3425 PF11905.3 KIA75584.1 - 1.3e-32 112.5 2.1 2.3e-32 111.7 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) ADH_N PF08240.7 KIA75585.1 - 5e-16 58.4 0.0 9.9e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KIA75585.1 - 1.2e-09 37.8 0.0 6e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 KIA75585.1 - 0.017 13.9 0.2 0.025 13.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KIA75585.1 - 0.048 12.1 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein vMSA PF00695.14 KIA75586.1 - 1 8.5 3.6 1.1 8.3 2.5 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus AMP-binding PF00501.23 KIA75587.1 - 1.3e-32 112.7 0.0 4.5e-32 110.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KIA75587.1 - 1.6e-24 86.2 0.0 2.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KIA75587.1 - 1.3e-06 28.4 0.7 9.1e-06 25.6 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 KIA75587.1 - 1.5e-06 28.3 0.0 5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KIA75587.1 - 5.5e-06 25.9 0.0 2.6e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KIA75587.1 - 2.1e-05 24.2 0.2 6e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KIA75587.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3926 PF13080.1 KIA75587.1 - 0.098 12.2 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Epimerase PF01370.16 KIA75588.1 - 2.2e-20 73.1 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75588.1 - 3.2e-13 49.0 0.0 4.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KIA75588.1 - 5.6e-09 36.2 0.4 1.2e-08 35.2 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KIA75588.1 - 1.6e-08 33.7 0.0 1.1e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KIA75588.1 - 4.5e-08 33.1 0.0 7.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75588.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KIA75588.1 - 0.00095 19.5 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KIA75588.1 - 0.016 14.4 0.0 0.066 12.4 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 KIA75588.1 - 0.045 12.6 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain DIOX_N PF14226.1 KIA75589.1 - 8.2e-29 100.4 0.0 1.5e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KIA75589.1 - 5.1e-23 81.2 0.0 9.7e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAP_N PF01213.14 KIA75589.1 - 0.072 12.3 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.11 KIA75590.1 - 4.9e-29 101.1 37.8 4.9e-29 101.1 26.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KIA75590.1 - 3.4e-06 25.5 13.6 1.3e-05 23.5 7.0 2.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4538 PF15061.1 KIA75590.1 - 7.5 5.9 5.4 2.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Methyltransf_2 PF00891.13 KIA75591.1 - 1.2e-33 116.2 0.0 1.6e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KIA75591.1 - 0.0005 19.6 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75591.1 - 0.00055 20.4 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75591.1 - 0.0068 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75591.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF1731 PF08338.6 KIA75591.1 - 0.035 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) CheR PF01739.13 KIA75591.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_24 PF13412.1 KIA75591.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_6 PF03737.10 KIA75591.1 - 0.14 12.0 0.1 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase FAD_binding_4 PF01565.18 KIA75592.1 - 1.4e-24 86.1 0.4 3.6e-24 84.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KIA75592.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Myb_DNA-bind_6 PF13921.1 KIA75593.1 - 1.2e-15 57.3 8.1 1.5e-06 28.1 0.1 4.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KIA75593.1 - 2.7e-12 46.5 9.3 4.8e-05 23.3 0.1 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KIA75593.1 - 0.71 9.8 8.6 7.2 6.5 0.2 4.6 3 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain p450 PF00067.17 KIA75594.1 - 9.2e-67 225.5 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KIA75595.1 - 9.9e-26 89.8 0.5 1.7e-25 89.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75595.1 - 4.7e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.21 KIA75596.1 - 1.8e-70 237.3 0.3 3.8e-70 236.2 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75596.1 - 6.5e-32 109.8 0.0 1.4e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KIA75596.1 - 9.2e-23 81.0 0.0 1.5e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 KIA75596.1 - 2.3e-20 72.6 8.2 2.4e-11 43.7 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KIA75596.1 - 4e-20 72.1 0.4 9e-20 71.0 0.2 1.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KIA75596.1 - 7.6e-17 61.6 0.0 2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KIA75596.1 - 7.6e-16 58.3 0.0 2.8e-12 46.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 KIA75596.1 - 2.4e-15 56.6 0.0 5.8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KIA75596.1 - 2.3e-10 40.3 0.0 1.6e-07 31.2 0.0 3.3 3 1 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KIA75596.1 - 1.4e-09 37.7 0.0 2.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KIA75596.1 - 9.2e-09 34.8 0.0 5.3e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_11 PF08241.7 KIA75596.1 - 2.2e-08 34.4 0.0 8e-08 32.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75596.1 - 2.1e-07 31.5 0.0 2e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75596.1 - 1.7e-05 24.0 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DLH PF01738.13 KIA75596.1 - 2.8e-05 23.5 0.0 0.058 12.6 0.0 3.2 3 0 0 3 3 3 1 Dienelactone hydrolase family Thiolase_N PF00108.18 KIA75596.1 - 4.8e-05 22.4 0.0 9.6e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KIA75596.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KIA75596.1 - 0.00015 21.7 0.0 0.00071 19.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KIA75596.1 - 0.002 17.5 0.0 0.0055 16.1 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Abhydrolase_2 PF02230.11 KIA75596.1 - 0.0028 17.1 0.0 1.3 8.3 0.0 2.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KIA75596.1 - 0.11 10.9 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 KIA75596.1 - 0.28 9.8 0.9 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family Methyltransf_32 PF13679.1 KIA75596.1 - 0.4 10.3 0.0 0.92 9.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PhyH PF05721.8 KIA75597.1 - 2.5e-09 37.5 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KIA75597.1 - 0.00038 19.0 0.1 0.18 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 KIA75598.1 - 7.7e-09 34.7 0.2 1.3e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPOC PF07744.8 KIA75601.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 SPOC domain AMP-binding PF00501.23 KIA75602.1 - 3.5e-34 117.9 0.0 1.5e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 KIA75602.1 - 4.4e-26 91.3 0.0 7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KIA75602.1 - 9.7e-11 41.5 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KIA75602.1 - 1.2e-06 28.6 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KIA75602.1 - 0.00011 22.1 0.0 0.014 15.3 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KIA75602.1 - 0.00065 19.4 0.0 0.015 14.9 0.0 2.8 3 0 0 3 3 3 1 KR domain p450 PF00067.17 KIA75603.1 - 5.7e-46 157.0 0.0 9.1e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KIA75604.1 - 3.4e-28 98.4 0.0 9.7e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase adh_short PF00106.20 KIA75604.1 - 3.1e-25 89.0 0.0 5.8e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75604.1 - 2.4e-13 50.4 0.0 3.5e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75604.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KIA75604.1 - 8.3e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Dimerisation PF08100.6 KIA75604.1 - 0.035 13.9 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain Saccharop_dh PF03435.13 KIA75604.1 - 0.11 11.4 0.3 0.32 9.9 0.0 1.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KIA75604.1 - 0.12 12.2 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KIA75604.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 KIA75604.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KIA75604.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Shikimate_DH PF01488.15 KIA75604.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 KIA75605.1 - 8.9e-48 162.7 43.4 5.7e-45 153.5 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75605.1 - 1.2e-14 53.7 10.8 1.2e-14 53.7 7.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1646 PF07854.7 KIA75605.1 - 1.3 8.0 7.3 0.88 8.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1646) OATP PF03137.15 KIA75605.1 - 1.6 6.6 7.3 0.83 7.6 0.8 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Lactamase_B PF00753.22 KIA75606.1 - 0.0054 16.4 1.7 0.015 15.0 1.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KIA75606.1 - 0.0082 15.7 0.2 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KIA75606.1 - 0.098 12.3 0.1 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain GMC_oxred_N PF00732.14 KIA75607.1 - 5.7e-62 209.5 0.0 7e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KIA75607.1 - 8.5e-26 90.9 0.0 1.7e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KIA75607.1 - 6.6e-10 38.4 0.2 0.001 18.0 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KIA75607.1 - 2.8e-07 29.7 0.1 4.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KIA75607.1 - 0.00017 20.7 0.1 0.0048 16.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KIA75607.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KIA75607.1 - 0.00021 21.2 0.4 0.0006 19.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KIA75607.1 - 0.00062 18.7 0.1 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KIA75607.1 - 0.0018 16.9 0.1 0.003 16.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KIA75607.1 - 0.017 15.1 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75607.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KIA75607.1 - 0.035 13.1 0.2 0.14 11.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KIA75607.1 - 0.064 11.7 0.1 0.097 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KIA75607.1 - 0.099 13.0 0.3 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 KIA75608.1 - 3.3e-53 180.8 0.0 4.2e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KIA75609.1 - 3.1e-74 249.6 0.1 5.9e-74 248.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75609.1 - 1.1e-37 128.4 0.1 2.6e-37 127.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KIA75609.1 - 4.3e-32 110.1 4.4 9.3e-16 57.8 0.3 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 KIA75609.1 - 1.7e-26 93.3 0.4 1.5e-25 90.2 0.0 2.4 3 0 0 3 3 2 1 Acyl transferase domain PS-DH PF14765.1 KIA75609.1 - 1.2e-23 83.6 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KIA75609.1 - 3.6e-20 72.2 0.0 1e-19 70.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KIA75609.1 - 8.6e-16 58.1 0.0 2.1e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 KIA75609.1 - 1.4e-13 50.8 0.0 4.6e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KIA75609.1 - 1.2e-12 47.8 0.0 1.9e-09 37.4 0.0 3.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KIA75609.1 - 1.7e-12 47.1 0.0 4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KIA75609.1 - 1.5e-10 41.3 0.7 1.9e-08 34.5 0.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA75609.1 - 7.7e-09 35.0 0.0 2.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_11 PF08241.7 KIA75609.1 - 1.1e-08 35.4 0.0 3.5e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75609.1 - 1.3e-08 35.4 0.0 6.6e-08 33.1 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain DLH PF01738.13 KIA75609.1 - 6.2e-06 25.6 0.0 0.00011 21.5 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Methyltransf_25 PF13649.1 KIA75609.1 - 2.3e-05 24.6 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KIA75609.1 - 3.8e-05 23.2 0.0 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Thiolase_N PF00108.18 KIA75609.1 - 0.0001 21.4 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_2 PF02230.11 KIA75609.1 - 0.00017 21.1 0.0 0.0058 16.1 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ubie_methyltran PF01209.13 KIA75609.1 - 0.00076 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family COesterase PF00135.23 KIA75609.1 - 0.0012 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Methyltransf_26 PF13659.1 KIA75609.1 - 0.0015 18.5 0.0 0.0077 16.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KIA75609.1 - 0.0048 16.2 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Esterase PF00756.15 KIA75609.1 - 0.036 13.4 0.0 4.8 6.5 0.0 2.9 2 0 0 2 2 2 0 Putative esterase LIP PF03583.9 KIA75609.1 - 0.039 13.1 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase RrnaAD PF00398.15 KIA75609.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KIA75609.1 - 0.26 10.7 0.0 0.65 9.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase ketoacyl-synt PF00109.21 KIA75610.1 - 5e-68 229.3 0.5 1.6e-67 227.6 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75610.1 - 6.6e-63 212.9 0.0 1.7e-62 211.6 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75610.1 - 3.6e-59 200.3 0.0 5.7e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KIA75610.1 - 1.7e-55 187.5 0.2 3.5e-55 186.4 0.2 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KIA75610.1 - 3e-41 141.1 0.1 9.9e-41 139.4 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75610.1 - 5.3e-36 123.0 0.5 1.4e-34 118.4 0.0 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KIA75610.1 - 7e-18 64.9 0.0 2e-17 63.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75610.1 - 1.9e-11 43.9 0.0 8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75610.1 - 7.7e-10 39.3 0.0 2.3e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75610.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KIA75610.1 - 1.3e-07 31.1 0.2 1.6e-06 27.6 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KIA75610.1 - 8.2e-07 29.4 0.0 3e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KIA75610.1 - 6.2e-06 26.3 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KIA75610.1 - 7.6e-05 22.7 0.0 0.00028 20.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KIA75610.1 - 0.0021 17.1 0.5 0.0039 16.1 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KIA75610.1 - 0.0031 16.9 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Shikimate_DH PF01488.15 KIA75610.1 - 0.19 11.8 0.0 0.54 10.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF276 PF03434.8 KIA75610.1 - 0.44 9.4 0.0 0.8 8.6 0.0 1.3 1 0 0 1 1 1 0 DUF276 Golgin_A5 PF09787.4 KIA75610.1 - 4.3 5.7 0.0 6.9 5.0 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Abhydrolase_5 PF12695.2 KIA75611.1 - 1.8e-13 50.4 0.0 5.2e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KIA75611.1 - 5.4e-12 46.0 0.0 9.9e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KIA75611.1 - 0.00013 20.5 0.1 0.0038 15.7 0.0 2.6 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KIA75611.1 - 0.0054 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KIA75611.1 - 0.026 13.7 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Carn_acyltransf PF00755.15 KIA75612.1 - 1.4e-77 261.1 0.0 4.9e-41 140.5 0.0 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 KIA75612.1 - 5.1e-77 258.7 0.9 9.4e-77 257.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75612.1 - 3.1e-55 187.7 0.6 5.4e-55 186.9 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75612.1 - 1e-45 156.2 0.0 3.6e-45 154.3 0.0 2.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75612.1 - 1.4e-36 124.9 0.4 5e-36 123.1 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75612.1 - 1.2e-10 41.0 0.2 2.9e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA75612.1 - 1.7e-10 41.8 0.0 8.8e-10 39.5 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KIA75612.1 - 1.5e-06 28.3 0.5 4.4e-06 26.8 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KIA75612.1 - 3.6e-06 26.6 0.1 9e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.5 KIA75612.1 - 5.8e-05 22.8 3.9 0.00034 20.3 0.0 4.0 4 1 0 4 4 4 1 KR domain adh_short PF00106.20 KIA75612.1 - 0.00012 22.0 3.7 0.0062 16.4 0.0 4.3 4 0 0 4 4 4 1 short chain dehydrogenase Thiolase_N PF00108.18 KIA75612.1 - 0.00066 18.7 0.1 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain p450 PF00067.17 KIA75613.1 - 2e-53 181.5 0.0 2.9e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3303 PF11746.3 KIA75613.1 - 0.091 13.1 0.2 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) ABC_membrane PF00664.18 KIA75614.1 - 2e-83 279.9 29.9 1.3e-42 146.1 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KIA75614.1 - 3.4e-68 228.2 0.1 3.3e-34 118.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KIA75614.1 - 5.2e-16 58.5 5.0 6.5e-08 32.0 0.6 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KIA75614.1 - 1.1e-15 58.4 0.8 0.014 15.3 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_17 PF13207.1 KIA75614.1 - 5.2e-08 33.7 0.2 0.0058 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KIA75614.1 - 7.7e-08 31.3 1.4 0.0051 15.4 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KIA75614.1 - 1e-07 31.3 3.1 0.00022 20.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KIA75614.1 - 6.7e-07 29.5 0.8 0.019 15.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KIA75614.1 - 1.4e-06 27.5 0.2 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KIA75614.1 - 2.6e-06 27.4 1.0 0.047 13.4 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KIA75614.1 - 4.6e-06 27.0 1.4 0.0012 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KIA75614.1 - 1.3e-05 24.8 0.4 0.22 11.3 0.0 3.4 3 0 0 3 3 2 2 Part of AAA domain AAA_30 PF13604.1 KIA75614.1 - 2.3e-05 24.0 0.1 0.39 10.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KIA75614.1 - 6.4e-05 22.5 0.2 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KIA75614.1 - 0.0001 22.6 0.0 0.4 10.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain PRK PF00485.13 KIA75614.1 - 0.00016 21.2 0.5 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KIA75614.1 - 0.00049 20.1 6.7 0.39 10.6 0.5 3.3 2 2 0 2 2 2 2 AAA ATPase domain ATP-synt_ab PF00006.20 KIA75614.1 - 0.00072 19.1 0.4 0.71 9.3 0.0 2.6 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KIA75614.1 - 0.00091 18.9 0.8 0.75 9.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KIA75614.1 - 0.0011 18.1 1.7 0.59 9.1 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.1 KIA75614.1 - 0.0016 18.2 2.7 0.6 10.0 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KIA75614.1 - 0.002 17.9 0.1 1.7 8.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KIA75614.1 - 0.0024 17.3 0.2 1.1 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KIA75614.1 - 0.0028 18.1 0.1 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KIA75614.1 - 0.0029 17.0 2.5 0.29 10.5 0.1 3.1 4 0 0 4 4 3 1 AAA-like domain AAA_15 PF13175.1 KIA75614.1 - 0.0057 15.7 0.5 2.8 6.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 KIA75614.1 - 0.0091 15.9 0.5 2.3 8.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KIA75614.1 - 0.018 13.8 0.1 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KIA75614.1 - 0.026 14.1 0.6 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KIA75614.1 - 0.029 14.1 0.2 7.7 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KIA75614.1 - 0.032 12.8 0.2 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 KIA75614.1 - 0.036 13.9 0.2 4.2 7.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 KIA75614.1 - 0.051 13.1 0.1 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 KIA75614.1 - 0.085 12.5 0.4 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 KIA75614.1 - 0.087 12.7 0.3 17 5.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KIA75614.1 - 0.09 11.8 1.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 KIA75614.1 - 0.096 12.3 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.15 KIA75614.1 - 0.25 9.9 0.1 8.2 4.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.7 KIA75614.1 - 0.29 10.4 0.3 16 4.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 KIA75614.1 - 0.39 10.1 4.7 7.1 6.0 0.1 2.9 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4267 PF14087.1 KIA75615.1 - 2.4e-26 91.5 1.1 2.9e-26 91.2 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4243 PF14027.1 KIA75616.1 - 3.8e-86 289.5 0.0 5e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 KIA75617.1 - 3.5e-16 59.7 0.1 5e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KIA75617.1 - 2.5e-07 30.2 0.0 4.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KIA75617.1 - 2.9e-07 30.1 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75617.1 - 0.00022 20.0 0.0 0.00028 19.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KIA75617.1 - 0.0047 17.2 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KIA75617.1 - 0.0094 15.6 0.8 0.44 10.1 0.6 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KIA75617.1 - 0.075 12.9 1.6 0.32 10.8 1.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KIA75617.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_2 PF00891.13 KIA75618.1 - 6.5e-30 104.1 0.0 8.9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KIA75618.1 - 4e-06 26.5 0.2 1.3e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 Dimerisation domain NAD_binding_10 PF13460.1 KIA75619.1 - 5.7e-08 32.9 0.0 0.00052 20.0 0.0 2.3 2 1 0 2 2 2 2 NADH(P)-binding Semialdhyde_dh PF01118.19 KIA75619.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KIA75620.1 - 2e-54 184.7 0.0 2.7e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KIA75620.1 - 3.4e-37 127.9 0.0 5.8e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KIA75620.1 - 1.1e-07 31.0 0.5 9.4e-05 21.4 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KIA75620.1 - 1.3e-07 30.9 0.3 3.4e-05 22.9 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KIA75620.1 - 9e-05 22.6 0.0 0.0043 17.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KIA75620.1 - 0.00013 21.9 0.7 0.0003 20.7 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KIA75620.1 - 0.0025 16.7 0.1 0.0041 16.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KIA75620.1 - 0.0047 16.0 0.5 0.13 11.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KIA75620.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KIA75620.1 - 0.025 13.2 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KIA75620.1 - 0.046 14.1 1.8 0.57 10.6 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75620.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KIA75620.1 - 0.062 11.7 0.3 0.099 11.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KIA75620.1 - 0.075 12.0 0.3 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1772 PF08592.6 KIA75621.1 - 2.3e-23 82.4 5.1 2.9e-23 82.1 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Cytochrom_B_N PF00033.14 KIA75621.1 - 0.12 11.7 5.9 0.81 9.0 0.6 2.3 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB p450 PF00067.17 KIA75622.1 - 3e-61 207.3 0.0 3.6e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 KIA75623.1 - 3.3e-77 259.9 0.9 2.7e-73 247.0 0.0 3.1 3 0 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 KIA75623.1 - 6.7e-30 102.9 0.1 2.3e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 KIA75623.1 - 1.3e-29 101.7 0.3 3.2e-29 100.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KIA75623.1 - 1.5e-10 40.9 0.0 4.4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ketoacyl-synt PF00109.21 KIA75624.1 - 1.3e-23 83.7 0.4 1.3e-23 83.7 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KIA75624.1 - 4.6e-14 52.7 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KIA75624.1 - 2.2e-12 46.8 0.0 9.3e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KIA75624.1 - 1.5e-11 44.0 0.0 4.4e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 KIA75624.1 - 5.7e-09 36.0 0.5 2e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KIA75624.1 - 1.2e-06 28.3 1.1 5.7e-06 26.1 0.0 2.6 3 0 0 3 3 3 1 KR domain PP-binding PF00550.20 KIA75624.1 - 0.037 14.3 0.9 0.42 10.8 0.0 3.0 3 0 0 3 3 3 0 Phosphopantetheine attachment site Epimerase PF01370.16 KIA75624.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KIA75625.1 - 3.1e-43 147.7 0.0 4.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KIA75625.1 - 6.9e-06 26.1 1.3 6.9e-06 26.1 0.9 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75625.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KIA75625.1 - 0.00011 20.9 0.0 0.00016 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KIA75625.1 - 0.063 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 KIA75625.1 - 0.13 11.7 0.2 2 7.7 0.2 2.3 2 0 0 2 2 2 0 Putative esterase Dabb PF07876.7 KIA75626.1 - 4.9e-10 39.7 0.0 5.3e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 KIA75626.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase adh_short PF00106.20 KIA75627.1 - 1.2e-10 41.5 0.7 2.5e-05 24.2 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KIA75627.1 - 0.011 15.4 0.8 2.8 7.5 0.1 3.1 3 0 0 3 3 3 0 KR domain p450 PF00067.17 KIA75628.1 - 2e-67 227.7 0.0 2.5e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AflR PF08493.5 KIA75630.1 - 1.3e-93 313.0 12.9 1.3e-93 313.0 9.0 2.3 3 0 0 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KIA75630.1 - 4.6e-11 42.4 9.3 8.5e-11 41.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KIA75631.1 - 5.8e-14 52.3 0.4 5.8e-14 52.3 0.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KIA75631.1 - 3.6e-07 29.8 0.0 5e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KIA75631.1 - 7e-06 25.8 0.3 9.8e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KIA75631.1 - 3.6e-05 23.6 0.0 5.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peroxidase_2 PF01328.12 KIA75632.1 - 2.1e-42 144.9 0.0 2.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.17 KIA75633.1 - 1.3e-54 185.4 0.0 1.8e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KIA75634.1 - 3.1e-79 266.0 0.0 7.6e-79 264.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75634.1 - 3.5e-43 148.1 0.0 8.1e-41 140.3 0.0 3.0 2 1 1 3 3 3 1 Acyl transferase domain Thioesterase PF00975.15 KIA75634.1 - 1.9e-36 126.4 0.0 4e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KIA75634.1 - 1.8e-32 111.6 0.0 4.2e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KIA75634.1 - 2.1e-21 75.9 6.1 5e-12 45.8 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KIA75634.1 - 1.5e-14 53.8 0.0 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 KIA75634.1 - 5.8e-08 32.6 0.2 0.0015 18.3 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KIA75634.1 - 8.3e-06 25.8 0.3 0.0049 16.7 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KIA75634.1 - 0.00028 19.9 0.0 0.00056 18.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain p450 PF00067.17 KIA75635.1 - 5e-47 160.4 0.0 9.6e-47 159.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 KIA75636.1 - 1.2e-16 61.3 0.2 1.5e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 EthD domain GST_N PF02798.15 KIA75637.1 - 4e-11 42.9 0.0 9.3e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KIA75637.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KIA75637.1 - 5.1e-09 36.0 0.0 7.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KIA75637.1 - 3.3e-07 30.1 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KIA75637.1 - 4.3e-05 23.9 0.0 6.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KIA75637.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 KIA75638.1 - 1.1e-34 119.7 1.6 1.7e-34 119.1 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75638.1 - 6.1e-28 98.1 0.1 7.3e-28 97.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75638.1 - 1.2e-17 64.2 1.0 1.7e-17 63.6 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75638.1 - 0.00052 19.5 0.3 0.00069 19.1 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KIA75638.1 - 0.024 15.2 0.1 0.047 14.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KIA75638.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KIA75638.1 - 0.048 12.7 0.2 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KIA75638.1 - 0.067 12.3 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Aldo_ket_red PF00248.16 KIA75639.1 - 3.5e-60 203.2 0.0 4e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_3 PF13738.1 KIA75640.1 - 1.6e-21 77.3 0.0 6.5e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KIA75640.1 - 3.6e-18 65.0 0.0 2.8e-16 58.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KIA75640.1 - 5e-11 42.4 0.4 3.2e-08 33.4 0.0 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KIA75640.1 - 3.6e-07 29.4 0.1 1.2e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KIA75640.1 - 0.051 13.9 0.3 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KIA75640.1 - 0.067 12.0 0.5 0.34 9.7 0.0 2.3 2 2 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KIA75640.1 - 0.078 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DUF877 PF05943.7 KIA75640.1 - 0.12 10.7 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF877) NAD_binding_9 PF13454.1 KIA75640.1 - 0.61 9.8 3.2 3.4 7.4 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.20 KIA75641.1 - 3.1e-26 92.2 1.6 4.4e-26 91.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75641.1 - 8.2e-18 65.0 0.1 1.1e-17 64.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75641.1 - 1.1e-08 34.9 1.0 1.8e-08 34.2 0.7 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KIA75641.1 - 7.7e-07 29.2 0.2 2.5e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KIA75641.1 - 6.6e-05 22.4 0.1 9.9e-05 21.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KIA75641.1 - 0.00049 19.4 0.1 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KIA75641.1 - 0.045 12.6 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain OppC_N PF12911.2 KIA75642.1 - 0.1 11.9 5.7 2.3 7.6 0.2 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF3671 PF12420.3 KIA75642.1 - 0.67 9.9 5.1 1.3 8.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function Abhydrolase_6 PF12697.2 KIA75643.1 - 2.4e-26 93.0 1.1 3.5e-26 92.4 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75643.1 - 1.3e-14 54.2 0.0 2.5e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KIA75643.1 - 1.8e-12 47.3 0.3 1.4e-08 34.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KIA75643.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KIA75643.1 - 0.011 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 KIA75643.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KIA75643.1 - 0.13 11.4 0.1 0.95 8.6 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Aldo_ket_red PF00248.16 KIA75644.1 - 2.2e-67 226.8 0.0 2.5e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 KIA75645.1 - 1.7e-33 115.4 0.7 3.4e-33 114.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KIA75645.1 - 0.057 13.3 6.4 0.12 12.3 4.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor MCM2_N PF12619.3 KIA75645.1 - 0.79 9.6 5.2 0.45 10.4 2.3 1.6 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 adh_short PF00106.20 KIA75646.1 - 6.9e-30 104.1 0.4 8.6e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75646.1 - 3.8e-20 72.6 0.1 5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KIA75646.1 - 2.8e-09 37.2 0.0 5.8e-09 36.2 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KIA75646.1 - 3.3e-09 36.6 0.2 4.9e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75646.1 - 1.5e-05 24.5 0.0 3.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KIA75646.1 - 1.8e-05 24.0 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KIA75646.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KIA75646.1 - 0.011 14.9 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 KIA75646.1 - 0.04 12.8 0.1 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain HMG-CoA_red PF00368.13 KIA75647.1 - 7.7e-153 508.5 5.3 1e-152 508.1 3.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KIA75647.1 - 3.8e-15 55.9 0.0 6.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KIA75647.1 - 2.6e-13 49.7 1.2 7.3e-13 48.2 0.9 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KIA75647.1 - 0.19 9.5 9.5 0.014 13.3 3.3 1.4 2 0 0 2 2 2 0 Patched family Fungal_trans PF04082.13 KIA75649.1 - 5.1e-23 81.2 0.8 9.9e-23 80.3 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_J PF04911.7 KIA75649.1 - 0.14 11.6 0.3 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase j chain DUF4263 PF14082.1 KIA75649.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Glyco_hydro_43 PF04616.9 KIA75650.1 - 4.7e-45 153.8 6.9 8.7e-44 149.7 1.9 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KIA75650.1 - 1.9e-38 131.4 0.6 1.9e-38 131.4 0.4 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 KIA75650.1 - 0.00041 19.8 3.7 0.00079 18.8 2.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain SKG6 PF08693.5 KIA75651.1 - 0.00066 18.9 0.6 0.0013 17.9 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RAMP PF04901.8 KIA75651.1 - 0.17 11.6 0.2 0.77 9.5 0.0 2.1 3 0 0 3 3 3 0 Receptor activity modifying family ketoacyl-synt PF00109.21 KIA75652.1 - 2.2e-78 263.2 0.0 5.2e-78 262.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75652.1 - 3.4e-59 199.5 0.3 3.4e-59 199.5 0.2 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KIA75652.1 - 3.4e-57 194.1 0.1 6.4e-57 193.2 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75652.1 - 3.1e-50 171.0 1.1 6.6e-50 169.9 0.8 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KIA75652.1 - 1.2e-46 158.7 0.5 1.2e-46 158.7 0.3 3.7 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75652.1 - 2.5e-41 140.2 0.2 1e-40 138.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75652.1 - 4.3e-19 68.3 1.3 2.4e-18 65.9 0.1 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KIA75652.1 - 2.3e-16 60.0 0.0 7.1e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75652.1 - 8.6e-14 52.5 0.0 3.9e-13 50.3 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75652.1 - 1.2e-10 41.3 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75652.1 - 1.1e-08 35.5 0.1 1.3e-07 32.1 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 KIA75652.1 - 5.6e-08 32.5 0.1 1.4e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KIA75652.1 - 2.6e-05 24.3 0.2 6.5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KIA75652.1 - 5.4e-05 23.5 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75652.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KIA75652.1 - 0.0017 17.4 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KIA75652.1 - 0.029 14.0 1.7 0.078 12.6 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.13 KIA75652.1 - 0.043 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family YflT PF11181.3 KIA75652.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT F420_oxidored PF03807.12 KIA75652.1 - 0.064 13.6 3.8 0.5 10.8 0.1 3.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 KIA75653.1 - 1.7e-57 194.9 0.0 2.7e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRAM_LAG1_CLN8 PF03798.11 KIA75654.1 - 1.9e-27 96.1 16.9 1.9e-27 96.1 11.7 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KIA75654.1 - 1.3e-08 34.2 0.0 3.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein p450 PF00067.17 KIA75655.1 - 9.2e-55 185.9 0.0 1.3e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KIA75656.1 - 6.2e-93 311.8 0.0 2e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_M3 PF01432.15 KIA75656.1 - 0.34 9.8 0.0 0.53 9.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M3 peroxidase PF00141.18 KIA75657.1 - 6.8e-86 287.4 0.0 1.6e-46 158.6 0.0 2.3 2 1 0 2 2 2 2 Peroxidase Ribonuclease_3 PF00636.21 KIA75658.1 - 2.5e-06 27.8 0.0 6.2e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KIA75658.1 - 7.1e-05 22.7 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like P5CR_dimer PF14748.1 KIA75659.1 - 1.2e-33 115.3 2.1 2.2e-32 111.2 0.6 2.7 1 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KIA75659.1 - 1.4e-15 57.5 0.5 3.7e-15 56.1 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KIA75659.1 - 8.8e-05 22.2 3.4 0.0012 18.5 2.3 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding_2 PF13380.1 KIA75659.1 - 0.0088 16.2 0.1 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain PDH PF02153.12 KIA75659.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 0 Prephenate dehydrogenase NMT1_2 PF13379.1 KIA75659.1 - 0.017 14.4 0.2 0.081 12.3 0.0 2.2 2 1 0 2 2 2 0 NMT1-like family ApbA PF02558.11 KIA75659.1 - 0.022 14.2 0.1 0.046 13.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 KIA75659.1 - 0.026 13.4 0.1 0.068 12.0 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein NAD_binding_2 PF03446.10 KIA75659.1 - 0.028 14.2 0.1 0.2 11.4 0.1 2.1 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amidohydro_4 PF13147.1 KIA75659.1 - 0.055 13.4 1.6 0.96 9.4 0.1 2.4 1 1 1 2 2 2 0 Amidohydrolase GFO_IDH_MocA PF01408.17 KIA75659.1 - 0.085 13.3 0.1 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PS_Dcarbxylase PF02666.10 KIA75661.1 - 2.6e-52 177.0 0.0 3.4e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Acetyltransf_1 PF00583.19 KIA75661.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4632 PF15451.1 KIA75661.1 - 0.0083 16.0 0.4 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4632) Acetyltransf_6 PF13480.1 KIA75661.1 - 0.1 12.5 0.2 0.4 10.6 0.1 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DsbC PF11412.3 KIA75662.1 - 0.033 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC DUF4409 PF14365.1 KIA75662.1 - 0.22 11.6 0.8 0.57 10.3 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4409) Arg_tRNA_synt_N PF03485.11 KIA75663.1 - 0.096 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Lactamase_B PF00753.22 KIA75664.1 - 6.3e-18 65.1 0.0 1.4e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KIA75664.1 - 2.4e-06 27.2 0.1 5.6e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KIA75664.1 - 0.03 14.0 0.2 0.7 9.5 0.0 2.4 1 1 1 2 2 2 0 Beta-lactamase superfamily domain MFS_1 PF07690.11 KIA75665.1 - 4.1e-22 78.3 26.0 3.9e-18 65.2 6.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KIA75665.1 - 1.2e-07 31.3 0.8 1.2e-07 31.3 0.5 1.8 2 0 0 2 2 2 1 Nodulin-like PVL_ORF50 PF07768.6 KIA75665.1 - 0.05 13.6 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family IPK PF03770.11 KIA75666.1 - 5.6e-58 195.8 0.0 1.1e-57 194.8 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KIA75666.1 - 0.039 13.6 0.1 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Sulfotransfer_3 PF13469.1 KIA75667.1 - 0.017 16.0 0.7 0.072 14.0 0.5 1.9 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.22 KIA75667.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase domain PNP_UDP_1 PF01048.15 KIA75668.1 - 5.3e-09 35.3 0.4 1.1e-08 34.3 0.2 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.24 KIA75668.1 - 3e-05 24.2 0.0 8.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KIA75668.1 - 0.00018 21.6 0.0 0.00059 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KIA75668.1 - 0.00022 20.9 0.4 0.0019 17.8 0.2 2.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KIA75668.1 - 0.00025 21.0 0.2 1.2 9.0 0.0 3.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 KIA75668.1 - 0.0013 18.9 0.0 0.0052 17.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 KIA75668.1 - 0.039 12.7 0.1 0.18 10.6 0.1 1.9 1 1 0 1 1 1 0 NB-ARC domain DUF2326 PF10088.4 KIA75668.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) AAA_33 PF13671.1 KIA75668.1 - 0.072 12.9 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 KIA75669.1 - 6.5e-25 87.9 0.0 9.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75669.1 - 8.4e-15 55.1 0.0 1.1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KIA75669.1 - 1.6e-09 37.3 0.0 2e-08 33.7 0.0 2.4 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KIA75669.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KIA75669.1 - 0.0031 17.5 0.0 0.0088 16.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KIA75669.1 - 0.0047 16.3 0.0 0.0086 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F-box-like PF12937.2 KIA75670.1 - 2.1e-05 24.1 0.1 4.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KIA75671.1 - 1.9e-21 76.1 51.9 2.2e-21 75.9 33.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily RHS_repeat PF05593.9 KIA75672.1 - 1.5e-12 47.3 49.5 0.075 13.2 0.2 15.0 12 4 2 14 14 14 7 RHS Repeat DUF4595 PF15283.1 KIA75672.1 - 6e-07 29.3 12.3 0.052 13.2 0.1 6.1 6 0 0 6 6 6 2 Domain of unknown function (DUF4595) with porin-like fold SET PF00856.23 KIA75674.1 - 6.2e-12 46.1 0.0 4.1e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KIA75674.1 - 2.7e-10 39.7 3.1 6.6e-10 38.5 0.3 2.7 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 KIA75674.1 - 0.00011 21.6 3.3 0.16 11.6 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KIA75674.1 - 0.00082 19.1 5.0 1.1 9.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KIA75674.1 - 0.15 12.7 1.1 19 6.2 0.0 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KIA75674.1 - 0.26 11.2 3.1 1.6 8.7 0.6 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KIA75674.1 - 6 7.6 9.5 0.33 11.6 0.1 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat ketoacyl-synt PF00109.21 KIA75675.1 - 5.5e-58 196.4 0.0 1.2e-57 195.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75675.1 - 2.4e-56 190.2 0.9 1.1e-55 188.0 0.1 2.7 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 KIA75675.1 - 4.4e-49 167.2 0.1 8.4e-49 166.3 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KIA75675.1 - 3.3e-48 164.6 0.0 6e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KIA75675.1 - 1.4e-43 148.6 0.1 5.6e-43 146.7 0.1 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75675.1 - 7.9e-37 125.7 1.1 2.4e-36 124.1 0.7 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75675.1 - 2.5e-16 59.3 0.0 6.3e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA75675.1 - 2.5e-12 47.8 0.0 1.2e-11 45.6 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KIA75675.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KIA75675.1 - 5.8e-06 26.4 0.0 2.1e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KIA75675.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HAD_2 PF13419.1 KIA75676.1 - 6.4e-27 94.8 0.0 1e-26 94.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KIA75676.1 - 0.0041 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 KIA75676.1 - 0.089 11.7 0.0 0.36 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) FAD_binding_4 PF01565.18 KIA75677.1 - 5.8e-23 80.9 1.5 1.2e-22 79.8 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75677.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KIA75678.1 - 4.2e-69 233.2 0.0 5.4e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KIA75679.1 - 7.7e-14 52.1 0.0 1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75679.1 - 2.1e-11 43.7 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KIA75679.1 - 2.8e-06 26.0 0.1 0.00022 19.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 KIA75679.1 - 7.3e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KIA75679.1 - 2.1e-05 24.3 0.0 5e-05 23.1 0.0 1.6 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 KIA75679.1 - 0.026 12.7 0.0 0.036 12.3 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 KIA75679.1 - 0.038 13.2 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KIA75679.1 - 0.052 13.1 0.0 0.083 12.4 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 KIA75680.1 - 8.9e-18 64.7 0.8 1.4e-17 64.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75680.1 - 2.4e-10 40.3 0.2 3.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KIA75680.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KIA75680.1 - 0.00039 19.9 0.2 0.00083 18.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KIA75680.1 - 0.0026 17.7 1.9 0.042 13.8 1.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KIA75680.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tweety PF04906.8 KIA75680.1 - 0.13 10.6 0.1 0.53 8.6 0.0 1.8 2 0 0 2 2 2 0 Tweety GST_N_3 PF13417.1 KIA75681.1 - 2.2e-14 53.4 0.0 4.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KIA75681.1 - 1.8e-12 47.0 0.0 3.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KIA75681.1 - 3.3e-12 46.3 0.0 6.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KIA75681.1 - 1.9e-08 34.1 0.1 3.6e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KIA75681.1 - 2.6e-08 33.7 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KIA75681.1 - 0.00049 20.5 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KIA75681.1 - 0.08 13.3 0.0 0.58 10.5 0.0 2.0 1 1 1 2 2 2 0 MetRS-N binding domain DUF3750 PF12570.3 KIA75682.1 - 0.18 12.1 0.6 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) ADH_N PF08240.7 KIA75684.1 - 7.9e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KIA75684.1 - 2.2e-07 30.4 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KIA75685.1 - 4.7e-10 38.7 0.1 7.2e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75685.1 - 3.6e-08 33.1 10.8 6.4e-08 32.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KIA75686.1 - 2.3e-11 43.3 0.2 5.5e-11 42.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KIA75686.1 - 7.6e-09 34.9 1.0 0.0027 16.6 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KIA75686.1 - 3.3e-05 22.9 0.4 0.0024 16.8 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KIA75686.1 - 0.0019 16.7 0.1 0.15 10.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KIA75686.1 - 0.0042 17.0 0.0 0.041 13.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KIA75686.1 - 0.03 13.6 0.6 0.06 12.7 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3215 PF11503.3 KIA75686.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) AlaDh_PNT_C PF01262.16 KIA75686.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 KIA75687.1 - 5e-62 209.9 0.0 6e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KIA75688.1 - 1.8e-244 810.6 0.3 4.3e-81 272.4 0.1 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KIA75688.1 - 1.1e-141 471.0 0.0 2.2e-36 125.2 0.0 6.4 6 1 0 6 6 6 5 Condensation domain PP-binding PF00550.20 KIA75688.1 - 2.4e-32 111.0 0.0 1.1e-12 48.0 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75688.1 - 4.6e-17 62.7 0.4 0.00018 22.3 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KIA75689.1 - 4.2e-18 65.1 27.6 4.6e-12 45.3 10.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily APH PF01636.18 KIA75690.1 - 0.00015 21.5 0.0 0.0017 18.1 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Beta_helix PF13229.1 KIA75691.1 - 3.5e-05 23.6 21.0 3.5e-05 23.6 14.5 2.2 1 1 1 2 2 2 1 Right handed beta helix region adh_short PF00106.20 KIA75692.1 - 3.5e-27 95.3 2.1 4.9e-27 94.8 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75692.1 - 2.6e-18 66.6 0.0 3.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75692.1 - 2.5e-10 40.3 0.2 3.7e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KIA75692.1 - 0.0026 17.7 0.2 0.0048 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KIA75692.1 - 0.013 14.4 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1776 PF08643.5 KIA75692.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KIA75692.1 - 0.026 13.3 0.2 0.048 12.5 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 KIA75692.1 - 0.034 13.6 0.2 0.069 12.6 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KIA75693.1 - 2.6e-10 39.6 0.0 3.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 KIA75694.1 - 1.8e-43 147.9 0.0 2.4e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KIA75694.1 - 4.7e-10 39.3 0.0 7.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Ribonuc_L-PSP PF01042.16 KIA75695.1 - 3.9e-06 26.6 0.0 5.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP HET PF06985.6 KIA75696.1 - 1.5e-09 38.1 0.0 1.3e-06 28.6 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAAA-beta PF15508.1 KIA75696.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ank_2 PF12796.2 KIA75698.1 - 1.6e-85 281.5 0.2 1.2e-20 73.6 0.0 7.5 3 3 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75698.1 - 9e-52 170.4 9.9 6.6e-07 28.8 0.0 11.8 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KIA75698.1 - 3.8e-42 141.9 3.8 4.4e-10 39.8 0.0 9.9 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KIA75698.1 - 2.9e-41 138.5 11.2 3.9e-06 26.9 0.0 10.8 7 3 3 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75698.1 - 1.6e-37 123.7 4.1 0.0012 18.8 0.0 12.0 13 0 0 13 13 13 8 Ankyrin repeat CBM_1 PF00734.13 KIA75700.1 - 7.7e-13 47.8 8.7 1.8e-12 46.6 6.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 KIA75700.1 - 1.1e-11 45.1 6.2 2.6e-11 43.9 4.3 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KIA75700.1 - 1.1e-07 32.0 3.7 1.9e-07 31.1 2.5 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.19 KIA75701.1 - 1.6e-77 261.0 24.9 2.5e-77 260.3 17.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75701.1 - 6.4e-22 77.7 34.1 4.3e-20 71.7 16.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MU117 PF15474.1 KIA75702.1 - 4.2e-10 39.9 0.6 5.4e-10 39.6 0.4 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene family Aspzincin_M35 PF14521.1 KIA75703.1 - 0.0014 19.1 0.2 0.0023 18.4 0.1 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pox_LP_H2 PF03356.10 KIA75703.1 - 0.061 12.9 0.1 0.5 10.0 0.0 2.0 1 1 1 2 2 2 0 Viral late protein H2 MdcE PF06833.6 KIA75703.1 - 0.11 11.6 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) NmrA PF05368.8 KIA75704.1 - 3.8e-23 81.9 0.0 5.3e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KIA75704.1 - 6.4e-07 29.5 0.1 9.2e-06 25.7 0.2 2.2 1 1 1 2 2 2 2 NADH(P)-binding adh_short PF00106.20 KIA75704.1 - 0.034 14.0 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KIA75704.1 - 0.039 13.3 0.1 0.079 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75704.1 - 0.17 10.5 0.0 0.54 8.8 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.18 KIA75705.1 - 8.1e-32 109.5 7.1 1.4e-31 108.8 4.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75705.1 - 2.6e-08 33.6 0.1 4.9e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like AMP-binding PF00501.23 KIA75706.1 - 1.1e-70 238.2 0.0 1.6e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KIA75706.1 - 2.6e-56 190.3 0.0 4e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KIA75706.1 - 9.3e-14 51.4 0.0 2.2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KIA75706.1 - 3.2e-11 43.1 0.1 1.1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KIA75706.1 - 1.3e-05 26.0 1.4 3.2e-05 24.7 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KIA75706.1 - 0.00045 19.0 0.0 0.0038 15.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KIA75707.1 - 1.3e-28 99.8 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KIA75707.1 - 8.9e-06 25.8 0.0 2.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KIA75707.1 - 0.0024 16.6 0.0 0.004 15.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KIA75707.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 KR domain AMP-binding PF00501.23 KIA75709.1 - 3.9e-291 964.3 0.0 1.9e-83 280.2 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KIA75709.1 - 2.2e-238 788.5 0.0 4.7e-43 147.1 0.2 9.2 8 1 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KIA75709.1 - 3e-51 171.5 0.0 7.9e-11 42.0 0.0 6.2 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75709.1 - 6.1e-13 49.5 0.4 1e-05 26.3 0.0 4.7 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KIA75709.1 - 0.0011 17.5 0.4 3.3 6.1 0.0 4.3 5 1 1 6 6 6 2 Alcohol acetyltransferase Transferase PF02458.10 KIA75709.1 - 0.012 14.1 0.1 0.94 7.8 0.0 3.0 3 0 0 3 3 3 0 Transferase family MFS_1 PF07690.11 KIA75710.1 - 3.5e-34 118.0 42.4 3.5e-34 118.0 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75710.1 - 1.7e-10 40.1 6.0 1.7e-10 40.1 4.2 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3808 PF10300.4 KIA75711.1 - 7.8e-152 506.0 0.0 9.7e-152 505.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KIA75711.1 - 0.023 14.3 1.9 0.41 10.3 1.7 2.7 2 0 0 2 2 2 0 TPR repeat DUF3857 PF12969.2 KIA75711.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) DSS1_SEM1 PF05160.8 KIA75712.1 - 5.5e-26 90.1 14.8 8.5e-26 89.5 10.2 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 KIA75713.1 - 2.5e-147 490.4 0.8 2.8e-147 490.2 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.3 KIA75713.1 - 0.1 11.5 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Mpv17_PMP22 PF04117.7 KIA75714.1 - 2.7e-22 78.1 0.1 7e-22 76.8 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Trs65 PF12735.2 KIA75715.1 - 6e-76 255.6 0.2 8.4e-76 255.2 0.1 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 KIA75716.1 - 8.8e-58 192.0 18.1 1.3e-13 50.6 0.5 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.21 KIA75716.1 - 2e-15 56.3 8.9 6.6e-08 32.2 0.2 2.7 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 KIA75717.1 - 7.9e-35 120.1 0.0 1.9e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KIA75717.1 - 3.8e-13 50.0 2.0 0.048 13.6 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KIA75717.1 - 2.6e-09 36.6 2.7 0.0068 15.6 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 KIA75717.1 - 5.7e-07 29.0 1.6 5.7e-07 29.0 1.1 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.1 KIA75717.1 - 7.5e-06 25.2 0.0 2.5 7.0 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KIA75717.1 - 7.8e-06 26.0 0.0 0.003 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KIA75717.1 - 2.9e-05 24.8 0.5 0.46 11.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KIA75717.1 - 6.8e-05 23.0 0.0 0.064 13.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.22 KIA75717.1 - 7.1e-05 22.2 2.5 7.1e-05 22.2 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 KIA75717.1 - 8.8e-05 21.9 0.3 0.071 12.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KIA75717.1 - 0.00014 21.1 0.0 0.46 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KIA75717.1 - 0.00017 21.4 0.1 0.064 13.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KIA75717.1 - 0.00027 21.2 0.1 0.46 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 KIA75717.1 - 0.00058 19.4 0.1 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 KIA75717.1 - 0.00082 19.1 8.3 0.0018 18.1 5.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 KIA75717.1 - 0.0009 19.7 0.0 0.058 13.8 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 KIA75717.1 - 0.0011 18.9 0.0 0.3 11.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KIA75717.1 - 0.0012 18.5 0.6 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 KIA75717.1 - 0.0015 18.0 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_23 PF13476.1 KIA75717.1 - 0.0027 18.0 0.2 0.23 11.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KIA75717.1 - 0.0036 17.4 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.10 KIA75717.1 - 0.0037 16.0 0.0 0.064 11.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 KIA75717.1 - 0.0047 16.4 1.9 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KIA75717.1 - 0.005 16.5 1.6 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KIA75717.1 - 0.0055 16.1 0.3 4.8 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Fer4_6 PF12837.2 KIA75717.1 - 0.0091 15.8 2.1 0.0091 15.8 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_13 PF13166.1 KIA75717.1 - 0.013 13.9 0.0 0.013 13.9 0.0 1.8 2 1 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 KIA75717.1 - 0.013 15.3 0.1 9 6.2 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 KIA75717.1 - 0.015 15.0 1.5 0.015 15.0 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KIA75717.1 - 0.019 15.6 3.3 0.042 14.5 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KIA75717.1 - 0.046 13.6 0.0 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 KIA75717.1 - 0.073 12.4 0.3 15 4.8 0.0 3.0 3 0 0 3 3 2 0 Thymidylate kinase Fer4_9 PF13187.1 KIA75717.1 - 0.085 13.1 10.8 0.059 13.6 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 KIA75717.1 - 0.1 12.1 2.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HflK_N PF12221.3 KIA75717.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal AAA_5 PF07728.9 KIA75717.1 - 0.11 12.2 0.1 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_7 PF12838.2 KIA75717.1 - 0.11 12.9 9.5 0.32 11.4 6.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 KIA75717.1 - 0.12 12.3 8.0 0.46 10.5 5.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_14 PF13173.1 KIA75717.1 - 0.13 12.1 0.1 12 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 KIA75717.1 - 0.17 12.2 0.2 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 KIA75717.1 - 0.17 10.6 0.1 9.3 5.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KIA75717.1 - 0.26 10.8 1.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_2 PF12797.2 KIA75717.1 - 9.3 6.4 10.0 0.52 10.3 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain p450 PF00067.17 KIA75718.1 - 3.1e-54 184.2 0.0 4.5e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KIA75719.1 - 7.7e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75719.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.14 KIA75719.1 - 0.078 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KIA75719.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KIA75719.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.14 KIA75720.1 - 4.4e-20 72.0 0.2 2.7e-19 69.4 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KIA75720.1 - 6e-10 38.5 0.3 3.8e-08 32.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KIA75720.1 - 2.4e-05 24.2 0.1 6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KIA75720.1 - 7.6e-05 23.0 0.4 7.6e-05 23.0 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KIA75720.1 - 0.0062 15.9 0.3 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 KIA75720.1 - 0.011 14.6 0.0 0.024 13.4 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 KIA75720.1 - 0.013 14.0 0.1 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 KIA75720.1 - 0.026 13.3 0.3 0.044 12.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KIA75720.1 - 0.031 14.1 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KIA75720.1 - 0.037 13.6 0.1 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KIA75720.1 - 0.049 13.0 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KIA75720.1 - 0.053 13.5 0.0 0.65 10.0 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75720.1 - 0.056 13.2 0.5 0.34 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.10 KIA75720.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.19 KIA75720.1 - 0.53 9.2 3.7 1.8 7.5 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UbiA PF01040.13 KIA75721.1 - 1.3e-25 90.1 16.5 1.3e-25 90.1 11.5 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family Transgly_assoc PF04226.8 KIA75721.1 - 0.3 11.1 4.2 0.42 10.7 1.9 2.1 2 0 0 2 2 2 0 Transglycosylase associated protein GMC_oxred_N PF00732.14 KIA75722.1 - 2.4e-61 207.4 0.0 3.2e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KIA75722.1 - 1.9e-40 138.4 0.0 3.4e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KIA75722.1 - 6.2e-09 35.2 0.2 1.2e-05 24.4 0.2 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KIA75722.1 - 1.6e-05 23.9 0.9 0.0028 16.5 0.6 2.5 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KIA75722.1 - 7.2e-05 22.7 0.4 0.00019 21.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KIA75722.1 - 0.00064 18.7 0.1 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KIA75722.1 - 0.0019 18.0 0.2 0.0052 16.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KIA75722.1 - 0.0021 17.1 0.4 0.004 16.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KIA75722.1 - 0.0042 17.1 0.5 2.8 7.9 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75722.1 - 0.02 14.6 1.2 0.031 14.0 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KIA75722.1 - 0.042 12.3 0.1 0.062 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ketoacyl-synt PF00109.21 KIA75723.1 - 6.6e-70 235.4 1.5 1.5e-69 234.3 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75723.1 - 6.4e-32 109.9 1.4 8.3e-31 106.3 0.3 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KIA75723.1 - 4.6e-30 104.3 0.0 7.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 KIA75723.1 - 5.9e-27 94.8 0.1 2.6e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KIA75723.1 - 2.7e-13 49.9 0.2 7.2e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA75723.1 - 1.9e-07 30.3 0.1 4.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 KIA75723.1 - 9.3e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KIA75723.1 - 0.00015 21.7 1.3 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KIA75723.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 KIA75724.1 - 8.5e-57 192.6 0.0 1.1e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cnd3 PF12719.2 KIA75724.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Prenyltrans_2 PF13249.1 KIA75725.1 - 6e-37 126.5 7.2 1e-12 48.4 0.0 6.0 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 KIA75725.1 - 7.4e-27 93.5 6.7 2.4e-11 43.5 0.1 6.3 4 2 1 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 KIA75725.1 - 3.7e-26 90.3 9.7 7.1e-08 31.8 0.2 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 KIA75725.1 - 5.3e-07 29.1 0.1 1.4 8.1 0.0 4.3 5 0 0 5 5 5 3 A-macroglobulin complement component Pec_lyase PF09492.5 KIA75725.1 - 8.3e-05 21.8 1.4 1.4 8.0 0.0 4.3 4 1 1 5 5 5 2 Pectic acid lyase DUF373 PF04123.8 KIA75726.1 - 0.048 12.6 1.0 0.98 8.3 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF373) TM_helix PF05552.7 KIA75726.1 - 0.12 12.0 1.6 0.28 10.8 1.1 1.5 1 0 0 1 1 1 0 Conserved TM helix Peptidase_M35 PF02102.10 KIA75727.1 - 7.3e-57 192.6 17.0 1.1e-56 192.0 11.8 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KIA75727.1 - 6.7e-08 33.1 1.6 6.7e-08 33.1 1.1 2.0 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 KIA75727.1 - 0.22 10.9 10.8 4.6 6.5 7.5 2.1 1 1 0 1 1 1 0 Putative peptidase family Abhydrolase_3 PF07859.8 KIA75728.1 - 1.5e-37 129.2 0.0 2.4e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KIA75728.1 - 0.00023 19.9 0.0 0.00048 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KIA75728.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family APH PF01636.18 KIA75730.1 - 2.5e-07 30.6 0.0 3.9e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KIA75730.1 - 0.00093 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KIA75730.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_4 PF07993.7 KIA75731.1 - 1.3e-33 115.9 0.0 3.6e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KIA75731.1 - 3e-33 114.8 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KIA75731.1 - 3.9e-11 42.8 0.0 7.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KIA75731.1 - 5.1e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KIA75731.1 - 0.00042 20.2 0.1 0.0016 18.3 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_3 PF03447.11 KIA75731.1 - 0.022 15.1 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KIA75731.1 - 0.096 12.6 0.0 1.3 9.0 0.0 2.7 1 1 0 1 1 1 0 NADH(P)-binding DXP_reductoisom PF02670.11 KIA75731.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.14 KIA75731.1 - 0.18 10.4 0.0 0.58 8.8 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MaoC_dehydrat_N PF13452.1 KIA75732.1 - 0.0004 20.1 0.0 0.094 12.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase AMP-binding PF00501.23 KIA75733.1 - 5.6e-65 219.3 0.0 7.3e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KIA75733.1 - 1.5e-09 38.6 0.1 3.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 KIA75734.1 - 3.2e-40 138.1 0.0 4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KIA75734.1 - 1.7e-08 33.9 0.0 2.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KIA75734.1 - 4.2e-07 29.0 0.0 6.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KIA75734.1 - 1.1e-05 23.9 0.0 1.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KIA75734.1 - 0.0082 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KIA75734.1 - 0.14 10.7 0.0 0.31 9.6 0.0 1.5 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.19 KIA75735.1 - 1.2e-35 122.5 19.6 1.2e-35 122.5 13.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KIA75735.1 - 6.5e-25 88.0 0.1 1.6e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KIA75735.1 - 9.6e-10 38.8 0.0 1.2e-08 35.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KIA75735.1 - 2.5e-05 23.4 33.2 0.00031 19.8 21.3 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 KIA75735.1 - 0.00048 19.5 0.0 0.038 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KIA75735.1 - 0.0048 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KIA75735.1 - 0.0055 15.9 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KIA75735.1 - 0.0071 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KIA75735.1 - 0.019 15.8 0.0 0.045 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KIA75735.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 KIA75735.1 - 0.037 13.0 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KIA75735.1 - 0.04 14.2 0.3 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KIA75735.1 - 0.059 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 KIA75735.1 - 0.068 13.2 7.4 0.097 12.7 1.2 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF AAA_14 PF13173.1 KIA75735.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KIA75735.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KIA75735.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Cornichon PF03311.9 KIA75736.1 - 2.6e-53 179.5 11.5 2.9e-53 179.3 8.0 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KIA75736.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Peptidase_M50 PF02163.17 KIA75736.1 - 0.31 9.9 4.6 0.39 9.6 3.2 1.2 1 0 0 1 1 1 0 Peptidase family M50 WD40 PF00400.27 KIA75737.1 - 2.3e-35 119.1 5.7 1.2e-07 31.3 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KIA75737.1 - 0.014 13.5 0.1 0.076 11.1 0.1 2.2 1 1 0 1 1 1 0 Nucleoporin Nup120/160 EF-hand_1 PF00036.27 KIA75738.1 - 2.4e-13 48.3 3.7 1.6e-06 26.9 0.2 3.6 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 KIA75738.1 - 1.3e-11 43.8 4.8 2.3e-11 43.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 KIA75738.1 - 1.5e-10 40.0 2.3 0.00014 21.4 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KIA75738.1 - 4.8e-10 39.4 4.3 6.6e-10 38.9 1.7 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KIA75738.1 - 2.7e-08 33.2 4.5 0.0018 17.8 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KIA75738.1 - 8.3e-05 21.7 5.0 0.043 13.1 0.2 3.3 3 0 0 3 3 3 2 EF hand MFS_1 PF07690.11 KIA75739.1 - 1e-45 156.0 48.9 1e-45 156.0 33.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75739.1 - 1.4e-14 53.5 13.5 1.4e-14 53.5 9.4 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Peptidase_M24 PF00557.19 KIA75740.1 - 8.3e-44 149.6 0.0 1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KIA75740.1 - 0.00046 19.9 3.7 0.00046 19.9 2.6 2.2 2 0 0 2 2 2 1 MYND finger FAD_binding_3 PF01494.14 KIA75741.1 - 1.4e-15 57.1 0.0 9.5e-15 54.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KIA75741.1 - 3.3e-06 27.4 0.0 5.7e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KIA75741.1 - 0.00035 19.5 0.6 0.00097 18.1 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KIA75741.1 - 0.00047 20.1 0.2 0.0012 18.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KIA75741.1 - 0.002 16.6 0.2 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KIA75741.1 - 0.0028 17.5 0.0 0.007 16.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KIA75741.1 - 0.016 14.3 5.4 0.037 13.1 1.0 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KIA75741.1 - 0.029 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 KIA75741.1 - 0.039 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KIA75741.1 - 0.052 12.6 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KIA75741.1 - 0.25 10.1 0.8 0.43 9.3 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain 3Beta_HSD PF01073.14 KIA75743.1 - 1.3e-56 191.3 0.0 1.7e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KIA75743.1 - 1.1e-40 139.5 0.0 1.6e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_S8 PF00410.14 KIA75743.1 - 2.1e-22 79.3 0.0 4.1e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S8 RmlD_sub_bind PF04321.12 KIA75743.1 - 6.1e-19 67.9 0.0 8.6e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KIA75743.1 - 1.1e-15 57.2 0.0 4.1e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KIA75743.1 - 2.3e-14 53.6 0.4 7.1e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KIA75743.1 - 1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KIA75743.1 - 2.3e-08 33.9 0.1 6.6e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KIA75743.1 - 1.5e-07 30.6 0.0 1.9e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KIA75743.1 - 8.4e-06 25.0 0.1 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ldh_1_N PF00056.18 KIA75743.1 - 0.00092 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.19 KIA75743.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KIA75743.1 - 0.03 14.0 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KIA75743.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NmrA PF05368.8 KIA75743.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Zip PF02535.17 KIA75744.1 - 0.18 10.7 0.8 0.23 10.4 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.11 KIA75745.1 - 8.9e-37 126.6 52.9 2.8e-36 124.9 36.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KIA75745.1 - 3e-07 29.3 3.7 2e-06 26.6 2.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KIA75745.1 - 0.37 9.3 30.9 0.42 9.1 9.5 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter PIP5K PF01504.13 KIA75746.1 - 5.3e-51 173.1 0.0 1.3e-50 171.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KIA75746.1 - 2.1e-27 95.9 0.0 3.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KIA75746.1 - 4.4e-14 52.1 3.2 4.4e-14 52.1 2.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.6 KIA75746.1 - 0.3 10.5 3.6 0.18 11.2 0.5 2.1 2 0 0 2 2 2 0 XPC-binding domain TPP1 PF10341.4 KIA75747.1 - 0.00042 20.2 0.0 0.00096 19.1 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SUR7 PF06687.7 KIA75748.1 - 1.2e-53 181.8 9.1 1.4e-53 181.6 6.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF348 PF03990.9 KIA75748.1 - 0.034 13.7 0.2 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF348) Cellulase PF00150.13 KIA75750.1 - 7.8e-56 189.3 4.6 9.9e-56 188.9 3.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pyr_redox_3 PF13738.1 KIA75751.1 - 2.1e-22 80.1 0.0 1.6e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KIA75751.1 - 6.1e-16 57.7 0.4 6.5e-15 54.3 0.3 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KIA75751.1 - 4e-12 45.9 0.0 1.1e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KIA75751.1 - 5.9e-10 38.5 0.0 1.6e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KIA75751.1 - 6.3e-05 22.0 0.0 0.011 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KIA75751.1 - 0.00011 21.9 0.0 0.00066 19.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KIA75751.1 - 0.019 15.3 0.0 6.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KIA75751.1 - 0.019 14.0 0.0 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Trp_DMAT PF11991.3 KIA75752.1 - 8.1e-95 318.0 0.0 1.1e-94 317.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase WD40 PF00400.27 KIA75753.1 - 4.2e-25 86.6 20.6 4.6e-10 38.9 0.2 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat CPSF_A PF03178.10 KIA75753.1 - 0.0041 16.2 0.0 0.017 14.1 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region XPG_N PF00752.12 KIA75754.1 - 1.2e-36 124.9 0.0 3.6e-36 123.4 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KIA75754.1 - 6.2e-25 87.0 0.0 1.5e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KIA75754.1 - 0.00028 21.0 0.0 0.00078 19.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 KIA75754.1 - 0.00036 19.8 3.9 0.00036 19.8 2.7 4.0 4 0 0 4 4 4 1 Ubiquitin interaction motif XPG_I_2 PF12813.2 KIA75754.1 - 0.0027 17.2 0.0 0.0078 15.7 0.0 1.7 1 1 0 1 1 1 1 XPG domain containing Transposase_20 PF02371.11 KIA75754.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Pil1 PF13805.1 KIA75755.1 - 2.8e-151 502.2 0.5 3.3e-151 501.9 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KIA75755.1 - 0.084 12.1 2.1 0.17 11.1 1.5 1.5 1 0 0 1 1 1 0 FAM92 protein V_ATPase_I PF01496.14 KIA75755.1 - 0.28 8.9 2.2 0.36 8.6 1.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KIA75756.1 - 3.8e-12 45.8 16.0 6.2e-12 45.1 11.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KIA75756.1 - 4.5e-05 23.3 14.8 0.00012 21.8 10.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 KIA75756.1 - 0.0021 17.8 0.7 0.0021 17.8 0.5 1.8 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 KIA75756.1 - 0.01 16.2 2.0 0.021 15.2 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3552 PF12072.3 KIA75756.1 - 0.056 12.6 8.3 0.079 12.1 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ketoacyl-synt PF00109.21 KIA75757.1 - 4.8e-72 242.4 0.1 9.2e-72 241.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75757.1 - 5.4e-56 189.1 0.0 1.9e-55 187.3 0.0 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KIA75757.1 - 4.5e-53 180.6 0.0 2.7e-51 174.8 0.0 2.7 2 1 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KIA75757.1 - 4e-44 150.4 0.0 1.3e-43 148.8 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KIA75757.1 - 4.6e-42 144.2 0.0 1.1e-41 142.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75757.1 - 4e-38 129.9 0.0 1.1e-37 128.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75757.1 - 3.3e-17 62.2 0.1 1.7e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KIA75757.1 - 7.1e-15 55.2 0.0 2e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75757.1 - 1.4e-13 51.8 0.0 8.8e-13 49.2 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75757.1 - 2.5e-11 43.5 0.0 5.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75757.1 - 4.9e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KIA75757.1 - 5.9e-08 32.4 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KIA75757.1 - 1.5e-07 31.9 0.0 8.9e-07 29.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KIA75757.1 - 4.9e-06 26.7 0.1 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KIA75757.1 - 7.4e-06 25.2 0.0 1.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KIA75757.1 - 2.2e-05 24.8 0.0 6.6e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KIA75757.1 - 0.0012 18.3 0.0 0.017 14.4 0.0 2.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Thiolase_N PF00108.18 KIA75757.1 - 0.0081 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 KIA75757.1 - 0.0087 15.1 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 KIA75757.1 - 0.15 11.5 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FSH1 PF03959.8 KIA75758.1 - 6.1e-27 94.4 0.0 7.6e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KIA75758.1 - 0.035 13.9 0.1 3.1 7.6 0.0 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KIA75759.1 - 3.6e-27 95.0 49.5 1.2e-22 80.1 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 KIA75761.1 - 0.00036 20.2 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_43 PF04616.9 KIA75762.1 - 3.9e-68 229.6 7.4 4.9e-68 229.3 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ank_2 PF12796.2 KIA75763.1 - 1.2e-52 176.2 6.6 1.2e-14 54.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75763.1 - 1.1e-50 166.9 13.8 6.5e-08 32.0 0.1 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 KIA75763.1 - 4.1e-45 150.7 14.9 1e-09 38.2 0.0 8.1 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75763.1 - 1.6e-38 126.8 11.6 6.4e-05 22.8 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KIA75763.1 - 4.8e-38 128.8 13.3 2.6e-11 43.7 0.0 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) DUF1843 PF08898.5 KIA75763.1 - 0.0015 18.5 0.1 0.032 14.2 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) Fungal_trans PF04082.13 KIA75764.1 - 2.1e-13 49.7 0.2 4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75764.1 - 4.1e-11 42.6 7.8 1e-10 41.3 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 KIA75765.1 - 1.9e-42 145.3 0.2 2.2e-42 145.0 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BCHF PF07284.6 KIA75765.1 - 0.085 12.7 1.2 0.15 11.8 0.8 1.3 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF4231 PF14015.1 KIA75765.1 - 0.17 11.8 1.2 0.3 11.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 KIA75766.1 - 8.5e-36 123.3 23.9 8.5e-36 123.3 16.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MOSC PF03473.12 KIA75768.1 - 5e-20 71.3 0.0 1.8e-19 69.5 0.0 2.0 3 0 0 3 3 3 1 MOSC domain Fer2 PF00111.22 KIA75768.1 - 3.8e-09 36.1 0.0 9.3e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 KIA75768.1 - 1.4e-05 25.5 0.0 3.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KIA75768.1 - 0.0041 17.0 0.6 0.47 10.3 0.1 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain 3-alpha PF03475.9 KIA75768.1 - 0.0077 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 3-alpha domain Sugar_tr PF00083.19 KIA75769.1 - 1.7e-70 237.8 34.7 5.7e-52 176.7 12.4 3.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KIA75769.1 - 1.5e-09 37.0 59.0 8.2e-07 28.0 8.0 4.6 1 1 3 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.1 KIA75769.1 - 3.1e-06 25.8 1.1 3.1e-06 25.8 0.8 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein adh_short PF00106.20 KIA75770.1 - 2e-22 79.9 0.3 3.1e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75770.1 - 1.1e-09 38.2 0.2 1.5e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KIA75770.1 - 0.00053 19.2 0.2 0.0012 18.0 0.1 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KIA75770.1 - 0.021 14.8 0.3 0.079 12.9 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KIA75770.1 - 0.047 13.1 0.0 0.092 12.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3632 PF12311.3 KIA75771.1 - 4.6e-26 91.7 0.0 7.2e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) APH PF01636.18 KIA75771.1 - 4.8e-09 36.2 0.0 5.2e-07 29.6 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KIA75771.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KIA75771.1 - 0.1 11.9 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Ribonuclease PF00545.15 KIA75772.1 - 0.0048 16.9 7.1 0.0048 16.9 4.9 2.1 2 1 0 2 2 2 1 ribonuclease PBCV_basic_adap PF08789.5 KIA75772.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain Sugar_tr PF00083.19 KIA75773.1 - 1e-71 241.8 23.9 1.2e-71 241.6 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75773.1 - 6.3e-19 67.8 27.4 6.3e-19 67.8 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KIA75774.1 - 4.8e-29 101.1 31.4 9.2e-28 96.9 21.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily AAT PF03417.11 KIA75775.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans_2 PF11951.3 KIA75775.1 - 3.4e-07 29.1 3.1 0.0096 14.5 2.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain NAAA-beta PF15508.1 KIA75775.1 - 5.1e-05 23.5 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MFS_1 PF07690.11 KIA75776.1 - 2.9e-38 131.4 49.9 2.9e-38 131.4 34.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KIA75776.1 - 1.1e-14 53.5 22.6 2.7e-14 52.2 15.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 KIA75777.1 - 7.2e-21 74.8 8.4 1.7e-15 57.3 1.3 3.6 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 KIA75777.1 - 3.6e-07 30.0 6.9 5.1e-06 26.2 0.5 3.5 4 0 0 4 4 4 2 KR domain adh_short_C2 PF13561.1 KIA75777.1 - 1.1e-06 28.5 0.0 0.0057 16.4 0.0 2.7 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KIA75777.1 - 0.00074 19.0 0.2 0.053 12.9 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 KIA75778.1 - 4.7e-20 71.4 3.1 8.2e-20 70.7 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75778.1 - 6.8e-07 29.1 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KIA75779.1 - 8.3e-17 61.6 0.1 2.2e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KIA75779.1 - 2.9e-08 33.6 0.0 7.5e-08 32.2 0.1 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KIA75779.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cupin_2 PF07883.6 KIA75780.1 - 3.7e-05 23.1 0.1 5.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.18 KIA75781.1 - 1.4e-25 89.3 0.4 2.8e-25 88.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75781.1 - 2.2e-09 37.0 0.0 2.4e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.17 KIA75782.1 - 1.3e-65 221.6 0.0 1.7e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotJA PF11007.3 KIA75782.1 - 0.17 11.5 0.9 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) adh_short PF00106.20 KIA75783.1 - 4.9e-12 46.0 0.7 8e-12 45.3 0.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75783.1 - 0.0092 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KIA75783.1 - 0.031 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Cupin_2 PF07883.6 KIA75784.1 - 1.4e-07 30.8 0.7 3.6e-07 29.5 0.0 2.0 2 1 1 3 3 3 1 Cupin domain adh_short PF00106.20 KIA75785.1 - 3.7e-23 82.2 4.0 9.9e-23 80.8 2.8 1.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75785.1 - 2.1e-20 73.5 0.0 2.5e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75785.1 - 3.1e-12 46.5 3.4 1.4e-11 44.3 2.4 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75785.1 - 0.00046 19.6 0.3 0.0032 16.9 0.2 2.0 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KIA75785.1 - 0.03 14.0 3.2 0.1 12.4 2.2 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 KIA75786.1 - 1.6e-54 184.3 1.2 5.8e-54 182.4 0.8 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KIA75786.1 - 8.4e-54 182.7 0.0 1.6e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KIA75786.1 - 7.9e-48 163.4 0.3 7.9e-48 163.4 0.2 1.9 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.21 KIA75786.1 - 2.2e-47 161.6 4.4 9.1e-24 84.3 0.7 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 KIA75786.1 - 2.2e-43 148.0 2.4 4.9e-43 146.9 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75786.1 - 7.5e-35 119.3 0.1 7.5e-35 119.3 0.1 3.5 4 0 0 4 4 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75786.1 - 2.8e-20 72.2 0.0 2.9e-19 68.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA75786.1 - 5.3e-12 46.7 0.0 6.7e-11 43.1 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KIA75786.1 - 0.00056 18.9 0.2 0.0011 17.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KIA75786.1 - 0.0063 16.7 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KIA75786.1 - 0.022 14.5 0.5 0.078 12.7 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KIA75787.1 - 8.3e-15 55.0 0.6 1.2e-14 54.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75787.1 - 9.1e-14 51.8 0.1 1.1e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KIA75787.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 KIA75787.1 - 0.0034 16.9 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 KIA75787.1 - 0.0066 15.6 0.0 0.015 14.4 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.11 KIA75787.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PAE PF03283.8 KIA75787.1 - 0.12 10.9 0.2 1.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Pectinacetylesterase TPR_12 PF13424.1 KIA75788.1 - 2.9e-64 212.9 16.6 1.3e-15 57.0 0.0 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KIA75788.1 - 1.1e-54 180.8 18.0 2.9e-09 36.5 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 KIA75788.1 - 3.1e-37 124.6 13.5 2.2e-05 23.8 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KIA75788.1 - 9.7e-36 118.8 14.1 0.00033 20.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 KIA75788.1 - 4.5e-32 109.5 8.1 1e-06 28.3 0.1 5.7 5 0 0 5 5 5 5 TPR repeat TPR_7 PF13176.1 KIA75788.1 - 2.4e-27 92.5 10.2 0.0003 20.3 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KIA75788.1 - 1.2e-23 81.3 9.5 0.04 14.5 0.0 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KIA75788.1 - 1.8e-17 63.4 4.8 0.0001 22.8 0.0 6.8 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KIA75788.1 - 1.9e-16 60.1 3.1 0.0041 17.4 0.0 6.0 3 1 3 6 6 6 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KIA75788.1 - 7e-13 48.0 0.2 2.5e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_8 PF13181.1 KIA75788.1 - 1.4e-12 46.4 12.4 0.013 15.1 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KIA75788.1 - 2.3e-11 42.9 0.0 1.8 9.2 0.0 8.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KIA75788.1 - 1.1e-10 40.8 5.5 0.68 10.2 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KIA75788.1 - 2.8e-09 36.8 15.0 0.29 11.6 0.0 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat PPR PF01535.15 KIA75788.1 - 5.6e-07 29.1 3.5 3.7 7.7 0.0 6.3 6 0 0 6 6 6 1 PPR repeat RPN7 PF10602.4 KIA75788.1 - 0.00012 21.4 0.6 5.5 6.3 0.0 4.7 3 1 2 5 5 5 1 26S proteasome subunit RPN7 HemY_N PF07219.8 KIA75788.1 - 0.00033 20.1 1.5 12 5.4 0.0 5.1 5 0 0 5 5 5 0 HemY protein N-terminus DUF2225 PF09986.4 KIA75788.1 - 0.0064 15.9 1.0 2.3 7.6 0.0 3.6 1 1 3 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) PPR_1 PF12854.2 KIA75788.1 - 0.009 15.4 0.5 1.9 8.0 0.0 3.5 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 KIA75788.1 - 0.022 14.7 5.2 4.4 7.3 0.0 5.2 7 0 0 7 7 6 0 PPR repeat family Bac_luciferase PF00296.15 KIA75789.1 - 1.5e-70 237.7 0.0 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Spuma_A9PTase PF03539.9 KIA75789.1 - 0.031 14.1 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) AP_endonuc_2 PF01261.19 KIA75789.1 - 0.088 12.0 0.1 3.2 6.9 0.0 2.6 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Aldedh PF00171.17 KIA75791.1 - 2.8e-43 147.9 0.3 3.4e-43 147.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KIA75792.1 - 1e-33 116.5 27.3 1e-33 116.5 18.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KIA75792.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.2 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding CMD PF02627.15 KIA75793.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family ATP-grasp_4 PF13535.1 KIA75793.1 - 0.052 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain ABM PF03992.11 KIA75794.1 - 4.5e-09 36.2 6.8 5.9e-05 23.0 0.5 2.7 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Isochorismatase PF00857.15 KIA75794.1 - 0.056 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family Cyclase PF04199.8 KIA75795.1 - 5.3e-16 58.7 0.0 9.2e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.13 KIA75797.1 - 1.9e-18 66.3 0.6 3.2e-18 65.5 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75797.1 - 1.7e-10 40.6 10.6 3.7e-10 39.5 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KIA75798.1 - 2.6e-19 70.1 0.0 1.3e-18 67.7 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KIA75798.1 - 2.2e-18 65.7 0.6 1.7e-17 62.8 0.2 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KIA75798.1 - 4.3e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KIA75798.1 - 0.00011 21.2 0.1 0.0095 14.8 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KIA75798.1 - 0.0027 17.5 0.1 0.13 12.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KIA75798.1 - 0.097 13.0 0.6 0.63 10.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KIA75799.1 - 1.3e-74 251.3 16.2 1.7e-74 251.0 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75799.1 - 5.4e-27 94.4 23.9 2.7e-21 75.6 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KIA75799.1 - 0.00094 17.4 2.9 0.0016 16.6 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 KIA75800.1 - 2.5e-21 75.5 1.0 4.3e-21 74.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75800.1 - 0.093 12.6 0.2 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Berberine and berberine like Sugar_tr PF00083.19 KIA75801.1 - 5.1e-76 256.0 20.0 5.1e-76 256.0 13.8 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 KIA75801.1 - 1e-54 185.2 0.0 1.3e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KIA75801.1 - 1.8e-16 59.8 28.4 1.8e-16 59.8 19.7 2.5 1 1 3 4 4 4 1 Major Facilitator Superfamily MFS_2 PF13347.1 KIA75801.1 - 7.2e-10 37.8 15.2 2.2e-05 23.0 4.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF4064 PF13273.1 KIA75801.1 - 1 9.5 8.0 0.33 11.0 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Transketolase_N PF00456.16 KIA75802.1 - 4.5e-18 65.1 0.5 4.9e-17 61.7 0.4 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KIA75802.1 - 1.2e-10 41.3 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KIA75802.1 - 0.00015 21.3 0.2 0.00015 21.3 0.1 2.4 4 0 0 4 4 4 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KIA75802.1 - 0.0015 17.3 0.0 0.003 16.3 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KIA75802.1 - 0.018 14.6 1.0 0.1 12.1 0.7 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NmrA PF05368.8 KIA75803.1 - 4.6e-22 78.4 0.1 5.9e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KIA75803.1 - 1.3e-12 48.0 0.2 2.1e-12 47.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KIA75803.1 - 8.4e-05 21.7 0.1 0.0002 20.4 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KIA75803.1 - 0.032 13.6 0.0 0.19 11.1 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KIA75804.1 - 1.8e-13 49.9 1.4 2.9e-13 49.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75804.1 - 1.5e-06 28.0 18.8 1.5e-06 28.0 13.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KIA75804.1 - 6e-05 23.1 20.1 0.00011 22.3 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KIA75804.1 - 0.0024 18.0 0.5 0.0024 18.0 0.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KIA75804.1 - 0.006 16.7 0.2 0.021 14.9 0.1 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KIA75804.1 - 0.017 15.3 1.3 0.017 15.3 0.9 3.2 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KIA75804.1 - 0.066 13.1 0.6 0.066 13.1 0.4 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KIA75804.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Macro PF01661.16 KIA75805.1 - 1.7e-30 105.3 0.0 2.8e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Macro domain adh_short PF00106.20 KIA75806.1 - 1.4e-15 57.6 0.3 8.3e-12 45.3 0.2 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KIA75806.1 - 6.8e-05 22.6 0.1 0.00013 21.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KIA75807.1 - 6.6e-17 61.2 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75807.1 - 8.8e-11 41.5 11.0 1.7e-10 40.6 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAN PF11640.3 KIA75807.1 - 0.2 11.4 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair adh_short_C2 PF13561.1 KIA75808.1 - 1.3e-38 133.1 0.3 1.5e-38 132.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KIA75808.1 - 6.1e-30 104.3 1.2 8.8e-30 103.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KIA75808.1 - 4.1e-12 46.1 0.8 7.1e-12 45.3 0.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75808.1 - 4.6e-06 26.2 0.2 1.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KIA75808.1 - 0.0006 19.5 1.8 0.0017 18.1 1.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KIA75808.1 - 0.019 14.0 0.3 0.054 12.5 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KIA75808.1 - 0.055 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cyclase PF04199.8 KIA75809.1 - 3.4e-11 43.1 0.0 6.7e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase HsbA PF12296.3 KIA75810.1 - 1.4e-11 44.2 0.1 2.6e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 Hydrophobic surface binding protein A T4SS PF07996.6 KIA75810.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins WXG100 PF06013.7 KIA75810.1 - 0.093 12.7 0.6 0.74 9.8 0.0 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG TACC PF05010.9 KIA75810.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) CPSF100_C PF13299.1 KIA75810.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.14 KIA75810.1 - 0.13 10.1 0.0 0.14 9.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_4 PF07993.7 KIA75811.1 - 1.1e-08 34.3 0.0 1.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein ketoacyl-synt PF00109.21 KIA75812.1 - 3.5e-63 213.4 0.2 6.6e-63 212.5 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75812.1 - 7.1e-60 202.9 0.0 1.3e-59 202.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75812.1 - 3.5e-58 197.0 2.9 6.7e-58 196.1 2.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KIA75812.1 - 7.8e-50 169.0 2.3 3.6e-28 98.4 0.1 2.6 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 KIA75812.1 - 2.7e-38 131.5 1.5 4e-22 78.9 0.1 2.9 2 0 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75812.1 - 7.2e-27 93.5 0.1 1.8e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KIA75812.1 - 3.9e-16 59.3 0.0 9.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KIA75812.1 - 4.2e-16 58.6 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75812.1 - 2.1e-13 50.3 0.0 4.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75812.1 - 9.5e-11 41.5 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KIA75812.1 - 1.7e-10 41.8 0.0 6.6e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KIA75812.1 - 1.5e-08 34.9 0.0 4.3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75812.1 - 2.2e-08 34.6 0.0 5.9e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KIA75812.1 - 4.7e-07 29.5 0.1 4.7e-07 29.5 0.1 2.3 3 0 0 3 3 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KIA75812.1 - 4.9e-07 29.1 0.0 8.8e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KIA75812.1 - 6.4e-05 23.2 0.0 0.00021 21.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KIA75812.1 - 0.0017 17.4 0.3 0.0033 16.4 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KIA75812.1 - 0.0045 16.6 0.7 0.012 15.2 0.5 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 KIA75812.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KIA75812.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 KIA75812.1 - 0.032 13.6 0.4 0.087 12.2 0.0 1.9 2 0 0 2 2 1 0 Putative methyltransferase NodS PF05401.6 KIA75812.1 - 0.049 13.0 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) Fn3-like PF14310.1 KIA75813.1 - 2.5e-24 85.0 0.1 5.3e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 KIA75813.1 - 1e-17 64.4 0.2 1.8e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KIA75813.1 - 1.8e-07 30.4 0.0 2.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Sugar_tr PF00083.19 KIA75815.1 - 2.5e-85 286.7 19.7 3e-85 286.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KIA75815.1 - 1.8e-21 76.2 32.1 1e-15 57.3 5.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.23 KIA75816.1 - 7.1e-58 196.6 0.0 9.5e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KIA75816.1 - 0.0079 15.7 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_1N PF02870.10 KIA75816.1 - 0.16 12.6 0.3 0.33 11.5 0.2 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF3425 PF11905.3 KIA75817.1 - 3.2e-35 120.9 0.2 5.5e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sugar_tr PF00083.19 KIA75817.1 - 2.3e-29 102.2 5.4 4.5e-25 88.1 0.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter NAD_binding_10 PF13460.1 KIA75817.1 - 1.3e-05 25.2 0.2 2.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding TauD PF02668.11 KIA75818.1 - 2e-49 168.5 0.3 2.3e-49 168.3 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_3 PF01596.12 KIA75818.1 - 0.027 13.5 0.0 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase 2OG-FeII_Oxy_3 PF13640.1 KIA75818.1 - 0.044 14.3 0.1 8.5 6.9 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TauD PF02668.11 KIA75819.1 - 7.2e-46 156.9 0.0 8.4e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMN_dh PF01070.13 KIA75820.1 - 5.7e-95 318.1 0.1 7.6e-95 317.7 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KIA75820.1 - 1.7e-06 27.2 0.8 0.00021 20.3 0.0 3.2 4 0 0 4 4 4 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KIA75820.1 - 3.3e-06 26.2 0.1 5.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KIA75820.1 - 0.041 13.1 0.1 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF3425 PF11905.3 KIA75821.1 - 1.5e-34 118.8 5.6 1.5e-34 118.8 3.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.13 KIA75821.1 - 0.0012 17.8 0.3 0.0068 15.3 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KIA75822.1 - 3.7e-21 75.2 56.7 6.6e-19 67.8 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 KIA75823.1 - 1.8e-22 79.9 0.2 2.6e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KIA75823.1 - 4.1e-07 29.7 0.1 6.8e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 KIA75824.1 - 3.5e-14 52.6 0.2 0.001 18.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Amino_oxidase PF01593.19 KIA75824.1 - 3.1e-05 23.2 0.0 0.048 12.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KIA75824.1 - 0.00018 21.4 0.0 0.00057 19.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KIA75824.1 - 0.00023 20.1 0.1 0.024 13.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KIA75824.1 - 0.0021 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KIA75824.1 - 0.0052 17.1 0.1 0.15 12.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KIA75824.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA75824.1 - 0.049 12.4 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain ketoacyl-synt PF00109.21 KIA75825.1 - 2.2e-79 266.5 0.1 1.1e-78 264.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75825.1 - 7.1e-46 156.9 0.0 3.5e-44 151.4 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA75825.1 - 1.3e-31 108.9 0.2 3.3e-31 107.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KIA75825.1 - 6.4e-18 64.9 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 KIA75825.1 - 9.2e-18 65.2 0.0 2.7e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KIA75825.1 - 2.8e-11 43.7 0.3 9.2e-09 35.5 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family PP-binding PF00550.20 KIA75825.1 - 1e-10 41.6 1.1 2.4e-10 40.4 0.7 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 KIA75825.1 - 1.7e-06 27.8 0.0 0.0098 15.6 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KIA75825.1 - 2.8e-06 26.5 0.0 6.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 KIA75825.1 - 0.022 14.2 0.0 0.44 10.0 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KIA75825.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ACP_syn_III PF08545.5 KIA75825.1 - 0.066 12.8 2.3 0.13 11.9 0.7 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.6 KIA75826.1 - 2.3e-19 70.0 0.0 2.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 EthD domain Methyltransf_2 PF00891.13 KIA75827.1 - 2.2e-35 122.0 0.0 2.9e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KIA75827.1 - 9.2e-05 22.9 0.2 0.00018 22.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75827.1 - 0.0076 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Wzt_C PF14524.1 KIA75827.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Wzt C-terminal domain Cu-oxidase_3 PF07732.10 KIA75828.1 - 9e-38 128.6 0.3 3.1e-37 126.8 0.2 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KIA75828.1 - 2.8e-32 111.1 8.9 4.7e-24 84.4 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KIA75828.1 - 6.6e-20 71.6 0.0 2e-18 66.8 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase ABC_tran PF00005.22 KIA75829.1 - 2.3e-49 167.2 0.0 5.4e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KIA75829.1 - 6.9e-48 163.4 36.5 4.2e-28 98.5 10.9 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KIA75829.1 - 2.9e-08 33.2 0.1 0.004 16.3 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KIA75829.1 - 1.3e-06 28.6 2.5 0.71 9.7 0.2 4.2 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KIA75829.1 - 4.2e-05 22.9 0.1 0.16 11.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KIA75829.1 - 8.9e-05 22.4 0.0 0.34 10.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KIA75829.1 - 0.00031 21.5 0.0 0.14 12.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KIA75829.1 - 0.00082 19.2 1.3 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KIA75829.1 - 0.0009 19.7 0.2 0.36 11.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KIA75829.1 - 0.0018 18.2 0.3 3 7.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KIA75829.1 - 0.0076 15.4 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KIA75829.1 - 0.01 15.2 0.0 2.9 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KIA75829.1 - 0.02 13.6 0.2 1 8.0 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 KIA75829.1 - 0.031 13.7 0.0 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KIA75829.1 - 0.076 13.3 1.2 2.2 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain PRK PF00485.13 KIA75829.1 - 0.097 12.2 0.2 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 KIA75829.1 - 0.15 12.3 6.6 0.93 9.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 KIA75829.1 - 0.55 9.2 0.0 1.3 7.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KIA75829.1 - 0.79 9.2 5.6 4.9 6.6 0.1 3.2 3 1 0 3 3 2 0 AAA domain Zn_clus PF00172.13 KIA75830.1 - 1.1e-08 34.8 10.1 1.7e-08 34.1 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FRQ PF09421.5 KIA75830.1 - 0.0037 15.1 1.0 0.0058 14.4 0.7 1.2 1 0 0 1 1 1 1 Frequency clock protein Methyltransf_12 PF08242.7 KIA75831.1 - 5.1e-13 49.3 0.0 9.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75831.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75831.1 - 2.5e-07 30.9 0.0 4.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75831.1 - 5.9e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75831.1 - 7.3e-06 26.3 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KIA75831.1 - 3.1e-05 24.1 0.1 6.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KIA75831.1 - 0.00017 22.0 0.0 0.00057 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75831.1 - 0.0015 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KIA75831.1 - 0.0035 17.3 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3077 PF11275.3 KIA75831.1 - 0.12 12.3 0.1 8.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) Zn_clus PF00172.13 KIA75832.1 - 2.8e-06 27.1 6.6 2.8e-06 27.1 4.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta_elim_lyase PF01212.16 KIA75833.1 - 1.4e-59 201.6 0.0 1.7e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KIA75833.1 - 0.015 13.6 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TCR PF03638.10 KIA75833.1 - 0.18 11.6 0.6 0.32 10.8 0.4 1.3 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain 2OG-FeII_Oxy PF03171.15 KIA75834.1 - 5.9e-15 55.3 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KIA75834.1 - 3e-07 30.9 0.1 7.6e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal ketoacyl-synt PF00109.21 KIA75835.1 - 4.3e-71 239.3 0.2 9.1e-71 238.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75835.1 - 7.2e-51 173.3 0.1 1.6e-50 172.2 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA75835.1 - 7.7e-34 116.0 0.2 2.1e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KIA75835.1 - 3.5e-11 43.2 0.5 1.2e-10 41.4 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA75835.1 - 8.8e-06 24.8 0.0 2.1e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KIA75835.1 - 0.021 14.5 0.4 0.084 12.6 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family AMP-binding PF00501.23 KIA75836.1 - 5.7e-39 133.6 0.0 7.9e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KIA75836.1 - 0.00042 21.2 0.1 0.0013 19.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Trp_DMAT PF11991.3 KIA75837.1 - 1.4e-66 225.2 0.0 5e-66 223.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Orexin PF02072.10 KIA75837.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Prepro-orexin polyprenyl_synt PF00348.12 KIA75838.1 - 4.6e-65 219.0 0.0 5.5e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase FAD_binding_3 PF01494.14 KIA75839.1 - 4.4e-16 58.8 0.2 1.2e-15 57.4 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FTO_NTD PF12933.2 KIA75839.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 FTO catalytic domain NAD_binding_8 PF13450.1 KIA75839.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 KIA75840.1 - 7.2e-58 196.2 0.0 9.7e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KIA75841.1 - 5.7e-39 133.8 32.9 5.7e-39 133.8 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KIA75841.1 - 0.0039 15.3 3.8 0.0072 14.4 1.9 2.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KIA75842.1 - 6.7e-40 136.8 51.6 1.1e-39 136.2 34.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KIA75842.1 - 5.4e-13 47.9 24.7 9.3e-13 47.2 17.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sporozoite_P67 PF05642.6 KIA75843.1 - 1.2e-05 23.3 17.5 0.00046 18.1 11.7 2.7 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Trp_DMAT PF11991.3 KIA75844.1 - 1.4e-66 225.1 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DAO PF01266.19 KIA75845.1 - 1.1e-10 40.9 2.9 4.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KIA75845.1 - 2.8e-10 39.7 7.9 6.8e-06 25.3 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KIA75845.1 - 1.2e-06 27.6 1.9 2.1e-06 26.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KIA75845.1 - 2.8e-05 23.3 0.0 0.00036 19.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KIA75845.1 - 3.9e-05 22.9 0.3 5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KIA75845.1 - 0.0013 17.2 0.7 0.0046 15.4 0.5 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KIA75845.1 - 0.0017 18.2 3.4 0.0028 17.5 1.9 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KIA75845.1 - 0.0022 16.9 1.3 0.0055 15.6 0.9 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KIA75845.1 - 0.0086 16.0 1.7 0.029 14.3 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KIA75845.1 - 0.022 13.7 0.9 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KIA75845.1 - 0.11 11.0 1.8 0.61 8.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KIA75845.1 - 0.12 12.4 0.1 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transferase PF02458.10 KIA75846.1 - 1.1e-05 24.1 0.0 2.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Transferase family Transferase PF02458.10 KIA75847.1 - 2.2e-26 92.3 0.0 3.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Transferase family AMP-binding PF00501.23 KIA75848.1 - 1.7e-152 507.6 0.0 9.5e-79 264.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KIA75848.1 - 6.2e-59 199.2 0.0 1.7e-34 119.0 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KIA75848.1 - 9.3e-14 51.4 0.2 2.2e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KIA75848.1 - 2e-08 35.0 0.0 0.014 16.3 0.1 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KIA75848.1 - 0.00095 19.4 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Transferase PF02458.10 KIA75848.1 - 0.1 10.9 0.0 1.9 6.8 0.0 2.3 3 0 0 3 3 3 0 Transferase family HET PF06985.6 KIA75851.1 - 0.003 17.7 0.1 0.11 12.6 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulfotransfer_3 PF13469.1 KIA75852.1 - 0.00082 20.3 0.4 0.0011 19.9 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family Peroxidase_2 PF01328.12 KIA75853.1 - 8.1e-43 146.2 0.1 9.4e-43 146.0 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1993 PF09351.5 KIA75854.1 - 3.9e-42 143.9 0.0 5.9e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) zf-met2 PF12907.2 KIA75854.1 - 2.3e-17 62.6 0.6 3.9e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KIA75854.1 - 0.00073 20.2 9.7 0.0022 18.7 6.7 1.8 1 0 0 1 1 1 1 4F5 protein family DUF2894 PF11445.3 KIA75854.1 - 0.8 9.9 3.9 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) MFS_1 PF07690.11 KIA75855.1 - 1.8e-34 119.0 66.3 8.8e-26 90.4 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75855.1 - 1.4e-10 40.3 36.6 5.7e-08 31.7 11.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_43 PF04616.9 KIA75856.1 - 1.5e-41 142.3 6.1 1.7e-41 142.1 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KIA75858.1 - 1.5e-27 96.1 0.2 2.6e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_BMRF2 PF04633.7 KIA75858.1 - 0.047 12.6 0.1 0.075 11.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein DUF2629 PF10945.3 KIA75858.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2629) Acetyltransf_1 PF00583.19 KIA75859.1 - 1e-12 47.9 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KIA75859.1 - 1.8e-07 31.2 0.2 3.5e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KIA75859.1 - 3.5e-07 30.2 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KIA75859.1 - 1.4e-06 28.3 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KIA75859.1 - 2.5e-06 27.7 0.0 3.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KIA75859.1 - 1.2e-05 24.9 0.0 3.6e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KIA75859.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KIA75859.1 - 0.00071 19.4 0.0 0.0024 17.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KIA75859.1 - 0.014 15.3 0.2 1.1 9.2 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KIA75859.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FMO-like PF00743.14 KIA75860.1 - 1.6e-29 102.5 0.0 8.7e-13 47.3 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KIA75860.1 - 1.9e-17 64.0 0.5 4.9e-16 59.3 0.4 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KIA75860.1 - 8.6e-08 32.1 0.1 0.00057 19.6 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KIA75860.1 - 4.5e-06 26.6 0.0 0.051 13.4 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KIA75860.1 - 6.5e-06 25.2 0.5 0.00069 18.6 0.0 3.0 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KIA75860.1 - 5.5e-05 23.1 0.0 0.0004 20.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain OCD_Mu_crystall PF02423.10 KIA75860.1 - 0.061 12.0 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family HI0933_like PF03486.9 KIA75860.1 - 0.12 10.7 0.3 0.32 9.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein RVT_1 PF00078.22 KIA75861.1 - 6.5e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_trans PF04082.13 KIA75862.1 - 9e-13 47.6 0.1 3.1e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75862.1 - 6.5e-08 32.3 11.3 1.2e-07 31.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.1 KIA75862.1 - 0.00083 19.2 3.0 0.00083 19.2 2.1 2.0 2 0 0 2 2 2 1 FlxA-like protein Pox_A_type_inc PF04508.7 KIA75862.1 - 0.02 14.6 1.0 0.097 12.5 0.7 2.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 KIA75862.1 - 0.036 14.0 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family ALIX_LYPXL_bnd PF13949.1 KIA75862.1 - 0.092 11.6 0.6 0.26 10.2 0.1 1.8 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Dickkopf_N PF04706.7 KIA75862.1 - 2.9 8.1 10.3 6.2 7.0 7.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 KIA75863.1 - 2.9e-26 92.0 80.7 9.1e-18 64.0 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KIA75863.1 - 0.027 14.2 9.8 0.031 14.0 1.5 3.3 4 0 0 4 4 4 0 MFS_1 like family MFS_2 PF13347.1 KIA75863.1 - 8.5 4.6 36.1 0.27 9.5 12.7 2.9 1 1 1 3 3 3 0 MFS/sugar transport protein Glyco_hydro_61 PF03443.9 KIA75864.1 - 3.1e-52 177.5 0.0 3.7e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 KIA75865.1 - 1.9e-23 82.7 0.0 3.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75865.1 - 4e-06 26.6 7.2 8.4e-06 25.6 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KIA75866.1 - 5.5e-29 100.9 40.8 6.7e-29 100.6 28.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KIA75866.1 - 0.11 12.9 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 KIA75867.1 - 9.4e-96 321.6 0.0 1.2e-95 321.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KIA75867.1 - 1.2e-07 31.5 0.7 7.8e-07 28.8 0.5 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 KIA75868.1 - 5e-20 72.2 0.1 1e-19 71.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KIA75868.1 - 0.031 13.4 0.0 3.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 KIA75868.1 - 0.034 13.7 0.0 0.096 12.2 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 KIA75868.1 - 0.039 13.0 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HipA_N PF07805.7 KIA75868.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 HipA-like N-terminal domain PALP PF00291.20 KIA75869.1 - 8.1e-33 113.9 0.0 9.3e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4628 PF15429.1 KIA75869.1 - 0.086 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) LYTB PF02401.13 KIA75869.1 - 0.096 11.5 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 LytB protein Epimerase PF01370.16 KIA75870.1 - 2.6e-13 49.9 0.0 7e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KIA75870.1 - 3.1e-12 45.7 0.0 4.6e-11 41.9 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KIA75870.1 - 1.6e-10 40.3 0.0 3.7e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KIA75870.1 - 2e-08 34.4 0.2 6.1e-07 29.6 0.0 2.5 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KIA75870.1 - 0.015 14.2 0.0 0.041 12.7 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M43 PF05572.8 KIA75871.1 - 7.5e-12 45.1 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KIA75871.1 - 0.00052 20.5 0.2 0.0015 19.0 0.2 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KIA75871.1 - 0.0028 17.7 0.0 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KIA75871.1 - 0.056 13.1 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.1 KIA75871.1 - 0.26 11.1 1.9 1.9 8.3 1.3 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 Abhydrolase_6 PF12697.2 KIA75872.1 - 9.9e-21 74.6 3.3 1.7e-20 73.8 2.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75872.1 - 2.4e-06 27.3 0.1 1.4e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KIA75872.1 - 4e-06 26.5 0.0 3.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KIA75872.1 - 0.00065 19.2 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.8 KIA75872.1 - 0.0015 18.1 0.0 0.0068 16.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 KIA75872.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Cellulase PF00150.13 KIA75873.1 - 1.1e-17 64.2 1.8 1.4e-17 63.8 1.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KIA75873.1 - 2.5e-07 31.0 0.0 6.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KIA75873.1 - 8.7e-07 28.1 0.0 1.4e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KIA75873.1 - 0.0019 17.3 0.1 0.0041 16.2 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase Acyl_transf_1 PF00698.16 KIA75874.1 - 2.8e-59 201.0 0.0 4.2e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA75874.1 - 1.4e-54 185.2 0.0 2.6e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KIA75874.1 - 4.3e-52 176.4 0.0 3e-51 173.6 0.0 2.3 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 KIA75874.1 - 2e-49 168.3 1.0 2.8e-48 164.6 0.7 2.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 KIA75874.1 - 1.7e-38 132.1 0.2 7.9e-38 129.9 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA75874.1 - 2e-28 98.6 0.4 4.2e-28 97.5 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KIA75874.1 - 5e-18 65.3 0.0 1.3e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KIA75874.1 - 7.5e-17 61.0 0.0 5.7e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KIA75874.1 - 1e-11 44.7 0.0 3.6e-11 43.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75874.1 - 2.7e-10 40.0 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75874.1 - 1.5e-09 38.4 0.0 9.5e-08 32.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75874.1 - 6.9e-09 36.0 0.0 1.9e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KIA75874.1 - 1.7e-08 34.2 0.1 5e-08 32.6 0.0 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KIA75874.1 - 2.3e-08 34.9 0.0 9.7e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.1 KIA75874.1 - 9.7e-06 25.8 0.0 3e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KIA75874.1 - 0.00019 20.5 0.2 0.00033 19.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KIA75874.1 - 0.0019 17.3 0.0 0.0056 15.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KIA75874.1 - 0.0073 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KIA75875.1 - 5.4e-35 120.5 0.0 6.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KIA75875.1 - 1.4e-06 27.9 0.0 4e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KIA75875.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KIA75875.1 - 0.052 13.5 0.0 3.8 7.4 0.0 2.7 2 1 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 KIA75875.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Fungal_trans PF04082.13 KIA75876.1 - 4.2e-31 107.7 0.3 6.7e-31 107.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75876.1 - 1.7e-07 31.0 16.7 3.4e-07 30.0 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RB_B PF01857.15 KIA75876.1 - 0.032 13.7 0.3 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain Epimerase PF01370.16 KIA75877.1 - 2.4e-06 27.1 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KIA75877.1 - 1.4e-05 25.2 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KIA75877.1 - 9e-05 21.5 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 KIA75877.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Aldedh PF00171.17 KIA75878.1 - 1.7e-138 461.8 0.0 2e-138 461.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KIA75878.1 - 0.027 13.6 0.0 0.087 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Abhydrolase_3 PF07859.8 KIA75879.1 - 3.1e-10 40.0 0.2 4.1e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KIA75879.1 - 4.4e-09 36.2 0.4 6.2e-09 35.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KIA75879.1 - 4.6e-06 26.6 0.6 6.7e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA75879.1 - 9.3e-06 25.0 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KIA75879.1 - 0.00064 18.5 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Lipase PF00151.14 KIA75879.1 - 0.0011 18.2 0.4 0.0011 18.2 0.2 1.6 2 0 0 2 2 2 1 Lipase PGAP1 PF07819.8 KIA75879.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase PF07224.6 KIA75879.1 - 0.003 16.3 0.3 0.0046 15.7 0.2 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 KIA75879.1 - 0.0031 16.9 0.0 0.0087 15.5 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 KIA75879.1 - 0.0041 16.0 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2305 PF10230.4 KIA75879.1 - 0.0057 16.1 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KIA75879.1 - 0.026 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.7 KIA75879.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Acyl-CoA_dh_1 PF00441.19 KIA75880.1 - 5.2e-34 117.5 6.9 8.8e-34 116.7 4.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KIA75880.1 - 1.1e-23 84.0 0.6 3.3e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KIA75880.1 - 1.1e-13 50.4 0.0 2.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KIA75880.1 - 1.8e-13 50.9 3.9 1.8e-13 50.9 2.7 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.15 KIA75880.1 - 0.0029 17.7 0.3 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase HTH_8 PF02954.14 KIA75880.1 - 2.3 7.8 6.3 41 3.8 0.1 3.5 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family AAA PF00004.24 KIA75882.1 - 1.5e-15 57.5 0.0 4.1e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KIA75882.1 - 0.0038 17.2 1.2 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KIA75882.1 - 0.006 16.7 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain FAM60A PF15396.1 KIA75882.1 - 0.012 15.3 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A AAA_5 PF07728.9 KIA75882.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KIA75882.1 - 0.043 14.6 0.4 0.38 11.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain CPT PF07931.7 KIA75882.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 KIA75882.1 - 0.16 11.7 0.6 0.58 9.9 0.0 2.2 3 0 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 KIA75882.1 - 0.34 10.7 2.8 1.5 8.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain Dicty_REP PF05086.7 KIA75883.1 - 0.086 10.5 0.2 0.11 10.1 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF427 PF04248.7 KIA75884.1 - 3.8e-29 100.2 1.1 4.2e-29 100.0 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.11 KIA75885.1 - 3.6e-16 58.8 39.6 1.1e-11 44.1 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KIA75886.1 - 1.3e-05 24.9 4.2 3.3e-05 23.6 2.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KIA75887.1 - 7.1e-24 84.1 61.5 3.5e-18 65.4 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_fiss_reg PF05308.6 KIA75887.1 - 7 5.9 5.8 10 5.4 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAD_binding_3 PF01494.14 KIA75888.1 - 7.4e-18 64.7 0.4 1.2e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KIA75888.1 - 4.6e-11 42.2 4.3 6e-05 22.1 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KIA75888.1 - 7e-06 26.0 0.4 1.7e-05 24.8 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA75888.1 - 7.6e-06 25.0 2.5 7.7e-06 25.0 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KIA75888.1 - 8.8e-06 25.6 0.7 2.4e-05 24.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KIA75888.1 - 9.8e-05 22.6 0.8 9.8e-05 22.6 0.6 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KIA75888.1 - 0.0001 21.2 0.1 0.00059 18.7 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KIA75888.1 - 0.00044 18.8 1.2 0.00072 18.1 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KIA75888.1 - 0.00065 18.9 0.2 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KIA75888.1 - 0.0019 17.8 2.2 0.0088 15.6 0.3 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KIA75888.1 - 0.0048 16.0 0.3 1.8 7.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KIA75888.1 - 0.011 14.4 0.3 0.09 11.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 KIA75888.1 - 0.012 14.7 0.1 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KIA75888.1 - 0.039 13.7 2.1 2.3 7.9 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KIA75888.1 - 0.044 13.8 0.1 0.13 12.2 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KIA75888.1 - 0.089 11.6 1.2 1.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Methyltransf_2 PF00891.13 KIA75889.1 - 1.2e-37 129.4 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KIA75889.1 - 2.9e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75889.1 - 1.9e-06 28.4 0.0 5.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75889.1 - 7.7e-06 26.3 0.0 2.7e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75889.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KIA75889.1 - 0.00018 20.9 0.0 0.00062 19.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain DREV PF05219.7 KIA75889.1 - 0.0097 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.4 KIA75889.1 - 0.024 14.0 0.0 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase IPPT PF01715.12 KIA75889.1 - 0.032 13.2 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 IPP transferase Methyltransf_26 PF13659.1 KIA75889.1 - 0.051 13.6 0.1 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 KIA75889.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 KIA75889.1 - 0.1 13.0 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.21 KIA75890.1 - 1.2e-75 254.3 0.4 5e-75 252.2 0.0 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75890.1 - 1.1e-52 179.3 0.2 3.4e-52 177.7 0.0 1.9 3 0 0 3 3 3 1 Acyl transferase domain p450 PF00067.17 KIA75890.1 - 6.5e-42 143.6 0.0 1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ketoacyl-synt_C PF02801.17 KIA75890.1 - 1.1e-33 115.6 1.7 2.8e-33 114.2 1.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KIA75890.1 - 1.2e-27 97.6 0.0 5.7e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KIA75890.1 - 8.1e-25 86.8 10.8 3e-13 49.8 2.8 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KIA75890.1 - 1.5e-07 31.5 13.2 2.1e-05 24.5 0.0 4.5 5 0 0 5 5 5 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75890.1 - 1.3e-06 28.2 1.2 0.067 12.9 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KIA75890.1 - 0.00035 19.6 0.1 0.001 18.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 KIA75890.1 - 0.0059 16.1 0.0 0.35 10.3 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold AA_permease_2 PF13520.1 KIA75891.1 - 7.4e-45 153.2 45.9 9.4e-45 152.9 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KIA75891.1 - 3.3e-24 85.1 39.4 4.3e-24 84.6 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2678 PF10856.3 KIA75891.1 - 0.85 9.3 7.0 0.24 11.1 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Ank_2 PF12796.2 KIA75892.1 - 3.3e-58 194.0 7.1 1.1e-18 67.2 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KIA75892.1 - 8e-50 164.2 22.5 1.9e-07 30.5 0.1 9.4 8 1 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KIA75892.1 - 3.5e-37 126.1 10.7 6.4e-08 32.9 0.0 7.3 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75892.1 - 1.5e-34 114.5 13.3 8e-06 25.6 0.0 10.0 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 KIA75892.1 - 1.5e-33 114.0 20.1 1.1e-08 35.0 1.7 8.5 3 2 6 9 9 9 7 Ankyrin repeats (many copies) F-box-like PF12937.2 KIA75892.1 - 1.2e-05 24.9 0.1 2.4e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KIA75892.1 - 0.0047 16.5 0.3 0.0096 15.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain Orthopox_F14 PF06076.7 KIA75892.1 - 0.13 12.3 0.0 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F14 protein CSD PF00313.17 KIA75894.1 - 6.5e-10 38.6 0.0 8.4e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain adh_short PF00106.20 KIA75896.1 - 1.4e-21 77.1 2.0 4.1e-21 75.6 0.2 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75896.1 - 1.5e-16 60.9 0.0 1.9e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75896.1 - 2e-08 34.1 0.3 5.6e-08 32.6 0.1 1.7 1 1 1 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KIA75896.1 - 0.00075 19.2 0.2 0.002 17.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyridox_oxidase PF01243.15 KIA75896.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AMP-binding PF00501.23 KIA75897.1 - 2.5e-87 292.9 0.1 3.4e-87 292.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CIA30 PF08547.7 KIA75897.1 - 4.8e-13 49.2 0.0 8.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) AMP-binding_C PF13193.1 KIA75897.1 - 1.8e-10 41.5 0.1 4.3e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Caps_synth PF05704.7 KIA75900.1 - 5.7e-07 28.9 0.0 1.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KIA75900.1 - 0.00038 20.8 0.0 0.00097 19.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AIG2 PF06094.7 KIA75901.1 - 9.9e-13 48.4 0.1 1.3e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family NeA_P2 PF12312.3 KIA75901.1 - 0.9 8.7 4.9 1.5 8.0 3.4 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.6 KIA75901.1 - 2.5 7.4 5.2 3.3 7.0 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Ank_2 PF12796.2 KIA75902.1 - 1.4e-118 387.4 2.2 1.7e-15 57.0 0.0 17.5 7 5 8 16 16 16 14 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KIA75902.1 - 2.9e-87 285.6 31.1 2.7e-08 34.1 0.0 25.5 15 6 9 25 25 25 18 Ankyrin repeats (many copies) Ank PF00023.25 KIA75902.1 - 3.4e-71 231.6 44.4 4.8e-07 29.2 0.0 27.2 27 2 0 27 27 27 17 Ankyrin repeat p450 PF00067.17 KIA75902.1 - 2e-68 231.0 0.0 3.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ank_5 PF13857.1 KIA75902.1 - 8.8e-63 206.9 45.7 2.3e-06 27.6 0.0 22.3 18 3 6 24 24 24 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KIA75902.1 - 3.7e-57 184.5 20.8 1.4e-05 24.8 0.0 26.5 29 0 0 29 29 29 11 Ankyrin repeat NACHT PF05729.7 KIA75902.1 - 9.3e-08 31.8 0.2 3.1e-07 30.2 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KIA75902.1 - 0.012 15.7 0.0 0.045 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 KIA75903.1 - 2.8e-07 30.3 13.6 2.8e-07 30.3 9.4 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.6 KIA75903.1 - 0.46 10.1 0.1 0.46 10.1 0.0 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-DHHC PF01529.15 KIA75903.1 - 5.2 6.4 6.3 9 5.6 4.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase MBOAT_2 PF13813.1 KIA75904.1 - 6.3e-21 74.2 1.9 2.9e-20 72.1 1.3 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 KIA75905.1 - 1.6e-33 115.9 56.1 7.4e-33 113.7 34.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75905.1 - 4.7e-08 32.0 16.3 4.7e-08 32.0 11.3 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Pex14_N PF04695.8 KIA75905.1 - 0.22 11.5 0.2 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.17 KIA75906.1 - 1.8e-63 214.6 0.0 2.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KIA75907.1 - 3.8e-73 246.0 0.2 7.2e-73 245.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75907.1 - 5.5e-60 202.1 1.8 7.5e-60 201.6 0.2 2.2 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.16 KIA75907.1 - 6.8e-58 196.4 0.4 1.5e-57 195.3 0.2 1.6 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KIA75907.1 - 4.6e-47 160.0 0.2 4.6e-46 156.7 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KIA75907.1 - 3.8e-46 157.5 0.1 3.8e-46 157.5 0.1 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75907.1 - 9.2e-39 131.9 0.2 4.6e-38 129.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain FSH1 PF03959.8 KIA75907.1 - 1.6e-27 96.3 0.0 3.9e-26 91.8 0.0 2.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) NAD_binding_1 PF00175.16 KIA75907.1 - 2.9e-24 85.7 0.0 8e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KIA75907.1 - 1e-21 76.4 0.1 2.1e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KIA75907.1 - 2.9e-13 49.7 0.0 6.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PP-binding PF00550.20 KIA75907.1 - 3.8e-05 23.8 0.1 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 KIA75907.1 - 0.00059 19.3 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.5 KIA75907.1 - 0.0012 18.4 0.2 0.003 17.1 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KIA75907.1 - 0.0038 16.2 0.0 0.0089 15.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_2 PF02230.11 KIA75907.1 - 0.051 13.0 0.1 0.16 11.4 0.1 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase NAD_binding_6 PF08030.7 KIA75907.1 - 0.087 12.7 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Macro_2 PF14519.1 KIA75907.1 - 0.19 10.8 0.0 0.45 9.5 0.0 1.6 1 0 0 1 1 1 0 Macro-like domain DUF915 PF06028.6 KIA75907.1 - 0.9 8.5 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) NAD_binding_10 PF13460.1 KIA75908.1 - 0.0046 16.9 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Arginase PF00491.16 KIA75909.1 - 1.6e-85 286.7 0.1 1.9e-85 286.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.3 KIA75910.1 - 2.9e-59 200.6 2.7 4.2e-59 200.0 1.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75910.1 - 8.5e-07 28.7 8.2 1.7e-06 27.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SoxD PF04267.7 KIA75910.1 - 0.08 12.7 0.6 6.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Sarcosine oxidase, delta subunit family AA_permease PF00324.16 KIA75911.1 - 7.2e-98 327.9 41.1 8.7e-98 327.7 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KIA75911.1 - 1.3e-24 86.5 43.6 1.6e-24 86.2 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KIA75912.1 - 1.8e-58 198.1 0.0 7.8e-58 196.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 KIA75913.1 - 2.4e-40 137.8 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KIA75913.1 - 5.1e-06 26.6 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KIA75913.1 - 4.5e-05 23.1 0.1 0.00028 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KIA75913.1 - 0.00025 21.0 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KIA75913.1 - 0.00038 20.4 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KIA75913.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KIA75913.1 - 0.0033 18.2 0.1 0.012 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KIA75913.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KIA75913.1 - 0.0099 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KIA75913.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KIA75913.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KIA75913.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KIA75913.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KIA75913.1 - 0.058 12.9 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KIA75913.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KIA75913.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KIA75913.1 - 0.095 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KIA75913.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KIA75913.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KIA75913.1 - 0.14 11.5 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 KIA75914.1 - 2.8e-128 428.5 10.5 3.7e-128 428.1 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KIA75914.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X zf-C2H2 PF00096.21 KIA75915.1 - 0.00067 19.8 3.1 0.00067 19.8 2.2 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type EBP50_C-term PF09007.6 KIA75915.1 - 0.072 12.9 3.8 0.29 11.0 2.6 2.1 1 0 0 1 1 1 0 EBP50, C-terminal C1_4 PF07975.7 KIA75915.1 - 0.097 12.6 0.1 0.097 12.6 0.1 2.1 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_4 PF13894.1 KIA75915.1 - 0.12 12.7 18.2 0.07 13.4 0.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KIA75915.1 - 0.84 10.0 18.1 0.85 10.0 3.0 3.7 3 0 0 3 3 3 0 Zinc-finger double domain NAD_binding_4 PF07993.7 KIA75916.1 - 3.3e-29 101.5 0.0 2.5e-28 98.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KIA75916.1 - 7.5e-23 80.5 0.0 1e-18 66.9 0.0 2.6 1 1 1 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KIA75916.1 - 5.5e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KIA75916.1 - 0.0027 17.9 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KIA75916.1 - 0.0042 15.8 0.0 0.0079 14.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KIA75916.1 - 0.054 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding AAA PF00004.24 KIA75917.1 - 2.3e-48 163.7 0.0 3.7e-43 146.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KIA75917.1 - 6.5e-05 22.4 0.0 0.00023 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KIA75917.1 - 0.00014 20.9 0.0 0.0004 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KIA75917.1 - 0.00027 21.7 0.0 0.0013 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KIA75917.1 - 0.00047 19.1 0.0 0.00079 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KIA75917.1 - 0.00086 19.3 0.2 0.025 14.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KIA75917.1 - 0.00095 19.3 0.0 0.0065 16.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KIA75917.1 - 0.0013 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KIA75917.1 - 0.0031 17.4 0.0 0.0077 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KIA75917.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KIA75917.1 - 0.005 16.5 0.1 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 KIA75917.1 - 0.0054 15.5 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KIA75917.1 - 0.018 14.2 0.1 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KIA75917.1 - 0.022 14.4 0.0 0.074 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KIA75917.1 - 0.03 13.4 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KIA75917.1 - 0.036 13.2 0.0 0.084 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 KIA75917.1 - 0.042 14.1 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KIA75917.1 - 0.057 13.2 0.2 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KIA75917.1 - 0.079 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KIA75917.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KIA75917.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KIA75917.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF815 PF05673.8 KIA75917.1 - 0.34 9.8 0.0 0.75 8.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GPI2 PF06432.6 KIA75918.1 - 5.1e-124 413.1 1.8 6.7e-124 412.8 1.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PBP1_TM PF14812.1 KIA75918.1 - 0.091 13.0 6.0 0.3 11.4 4.2 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KIA75918.1 - 0.25 10.4 10.5 0.63 9.1 7.3 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Fumble PF03630.9 KIA75919.1 - 9.2e-140 465.3 1.9 7e-139 462.4 1.3 1.9 1 1 0 1 1 1 1 Fumble DEAD PF00270.24 KIA75920.1 - 2.8e-38 131.0 0.0 5.7e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KIA75920.1 - 2.1e-21 75.5 0.1 6.6e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Polysacc_deac_1 PF01522.16 KIA75920.1 - 3.5e-17 62.1 0.0 7.3e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SNF2_N PF00176.18 KIA75920.1 - 0.0008 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2334 PF10096.4 KIA75920.1 - 0.028 13.8 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Fringe PF02434.11 KIA75921.1 - 3e-09 36.4 0.0 4.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KIA75921.1 - 0.033 13.8 2.0 0.072 12.8 1.4 1.5 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.7 KIA75921.1 - 0.055 12.9 0.8 0.11 12.0 0.6 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PAN_1 PF00024.21 KIA75921.1 - 0.057 13.1 1.5 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 KIA75921.1 - 0.22 11.1 2.0 0.43 10.2 1.4 1.4 1 0 0 1 1 1 0 PAN-like domain Pectate_lyase_3 PF12708.2 KIA75922.1 - 3.8e-39 135.1 13.1 8.7e-35 120.8 2.9 2.6 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KIA75922.1 - 0.073 12.5 0.4 1.5 8.3 0.1 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase MFS_1 PF07690.11 KIA75923.1 - 1.3e-36 126.0 21.8 1.3e-36 126.0 15.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_4 PF07993.7 KIA75924.1 - 1.4e-38 132.2 0.0 4.8e-38 130.4 0.0 1.9 3 0 0 3 3 3 1 Male sterility protein AMP-binding PF00501.23 KIA75924.1 - 2e-34 118.7 0.0 5.7e-34 117.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KIA75924.1 - 1.2e-12 47.7 0.0 2.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KIA75924.1 - 6.2e-05 23.1 0.0 0.00022 21.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KIA75924.1 - 0.0017 17.1 0.0 0.0087 14.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KIA75924.1 - 0.0031 17.1 0.1 0.013 15.2 0.1 1.9 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KIA75925.1 - 4.5e-30 104.3 0.1 7.5e-30 103.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75925.1 - 3.4e-08 33.2 9.5 3.4e-08 33.2 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 KIA75926.1 - 4.2e-30 103.9 0.5 1.1e-29 102.6 0.1 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KIA75926.1 - 5.4e-17 61.8 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KIA75926.1 - 2.2e-08 34.5 0.0 7.1e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Aldo_ket_red PF00248.16 KIA75927.1 - 1.2e-59 201.4 0.0 1.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DFP PF04127.10 KIA75928.1 - 1e-15 57.8 0.0 2.4e-05 24.0 0.0 3.3 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Abhydrolase_3 PF07859.8 KIA75929.1 - 8.6e-41 139.8 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KIA75929.1 - 1.9e-05 24.0 0.0 4.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KIA75929.1 - 0.00015 21.7 0.2 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75929.1 - 0.00038 20.2 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KIA75929.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KIA75929.1 - 0.0058 15.9 0.0 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KIA75929.1 - 0.022 13.2 0.0 0.094 11.1 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 KIA75929.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 KIA75929.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 KIA75929.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 KIA75929.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CENP-O PF09496.5 KIA75931.1 - 1.9e-27 95.3 0.0 3.7e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component TIR_2 PF13676.1 KIA75931.1 - 0.002 18.2 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 TIR domain Acatn PF13000.2 KIA75932.1 - 3.1e-142 474.9 25.3 3.6e-75 253.5 6.3 3.7 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Fungal_trans PF04082.13 KIA75933.1 - 2.8e-19 69.0 1.4 3.6e-19 68.6 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KIA75933.1 - 1.5e-12 47.7 0.1 6.4e-12 45.7 0.0 2.0 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KIA75933.1 - 1.9e-05 24.3 0.1 4.9e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KIA75933.1 - 0.00044 20.0 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KIA75933.1 - 0.051 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KIA75933.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF572 PF04502.8 KIA75934.1 - 1.5e-53 182.1 0.0 2.2e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) MFS_1 PF07690.11 KIA75934.1 - 7.6e-36 123.5 28.9 1.7e-33 115.8 13.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KIA75934.1 - 0.0055 15.2 10.1 0.51 8.7 0.1 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like TauD PF02668.11 KIA75935.1 - 1.5e-11 44.4 5.1 7.5e-06 25.7 0.3 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KIA75935.1 - 0.018 13.9 0.1 0.3 9.9 0.0 2.3 3 0 0 3 3 3 0 CsiD AMP-binding PF00501.23 KIA75936.1 - 2.1e-110 369.0 0.2 2.8e-58 197.3 0.0 4.2 2 2 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KIA75936.1 - 2.2e-21 76.0 0.0 1.4e-15 56.9 0.0 2.6 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 KIA75936.1 - 9.2e-07 29.0 0.0 2.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KIA75937.1 - 3.1e-30 104.9 0.0 1.1e-20 73.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.20 KIA75937.1 - 1.2e-09 38.2 0.1 2.6e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KIA75937.1 - 9.4e-05 21.9 0.0 0.0008 18.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KIA75937.1 - 0.022 14.7 0.0 0.31 11.0 0.0 2.3 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 KIA75937.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KIA75937.1 - 0.066 13.1 0.5 0.44 10.4 0.0 2.1 1 1 1 2 2 2 0 short chain dehydrogenase Glyco_hydro_3 PF00933.16 KIA75938.1 - 2.4e-89 299.2 0.0 3.2e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KIA75938.1 - 6.9e-54 182.7 0.0 4.8e-52 176.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KIA75938.1 - 7.6e-21 73.8 0.3 1.2e-20 73.1 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 KIA75939.1 - 3e-76 256.2 0.0 4.4e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KIA75939.1 - 8.3e-65 218.4 0.0 2.2e-64 217.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KIA75939.1 - 4.9e-24 84.0 0.1 1.2e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KIA75939.1 - 3.1e-15 56.1 0.0 6.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.13 KIA75940.1 - 4.3e-20 71.3 24.9 2.8e-10 39.9 4.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KIA75940.1 - 3.6e-08 32.6 4.6 3e-05 23.0 0.6 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain p450 PF00067.17 KIA75941.1 - 7.9e-32 110.3 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 KIA75942.1 - 5.7e-41 140.0 0.0 1.1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KIA75942.1 - 3.2e-06 26.5 1.9 0.017 14.3 0.3 2.5 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain Ifi-6-16 PF06140.8 KIA75943.1 - 2.6e-06 27.1 29.5 2.6e-06 27.1 20.5 2.0 2 0 0 2 2 2 1 Interferon-induced 6-16 family TMF_DNA_bd PF12329.3 KIA75944.1 - 6.5e-05 22.6 1.4 0.00027 20.6 1.0 2.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 KIA75944.1 - 0.015 14.6 1.8 0.015 14.6 1.3 2.2 3 0 0 3 3 3 0 Laminin Domain I Spc7 PF08317.6 KIA75944.1 - 0.029 13.0 1.4 0.051 12.2 0.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 KIA75944.1 - 0.039 13.7 1.9 0.13 12.0 0.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HALZ PF02183.13 KIA75944.1 - 0.044 13.4 0.2 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 KIA75944.1 - 0.31 10.5 3.0 0.73 9.3 0.4 2.6 1 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KIA75944.1 - 3 8.2 5.3 0.5 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 KIA75944.1 - 3.2 8.2 9.1 15 6.0 0.6 3.7 3 1 0 3 3 3 0 SlyX Trp_DMAT PF11991.3 KIA75945.1 - 7e-57 193.2 0.0 2.6e-44 151.8 0.0 2.2 2 0 0 2 2 2 2 Tryptophan dimethylallyltransferase EF-hand_1 PF00036.27 KIA75947.1 - 9.9e-35 115.2 13.6 3e-08 32.3 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KIA75947.1 - 1.2e-31 108.5 6.9 1e-16 60.8 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KIA75947.1 - 4.5e-29 97.6 11.3 1.2e-08 34.0 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KIA75947.1 - 1.3e-26 91.9 12.4 2.6e-12 46.1 0.5 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KIA75947.1 - 2.8e-25 86.4 12.3 7.2e-07 28.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KIA75947.1 - 2.3e-18 65.8 0.5 9.9e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KIA75947.1 - 1e-10 41.2 1.8 0.00028 20.5 0.1 2.2 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KIA75947.1 - 0.00051 20.0 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KIA75947.1 - 0.00074 19.0 0.0 0.63 9.6 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 KIA75947.1 - 0.00096 18.9 0.2 0.8 9.4 0.0 2.6 1 1 2 3 3 3 1 Tellurite resistance protein TerB EF-hand_10 PF14788.1 KIA75947.1 - 0.0073 15.9 0.8 0.029 14.0 0.0 2.2 3 0 0 3 3 3 1 EF hand Toprim_2 PF13155.1 KIA75947.1 - 0.012 15.9 0.3 5.3 7.4 0.0 2.2 1 1 0 2 2 2 0 Toprim-like Caleosin PF05042.8 KIA75947.1 - 0.019 14.5 0.0 1.7 8.1 0.0 2.2 1 1 0 2 2 2 0 Caleosin related protein DUF3164 PF11363.3 KIA75947.1 - 0.035 13.5 0.5 0.22 10.8 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3164) Toprim_4 PF13662.1 KIA75947.1 - 0.051 13.5 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Toprim domain RNA_pol_Rpb4 PF03874.11 KIA75947.1 - 0.1 12.5 0.3 14 5.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 GTPase_Cys_C PF12631.2 KIA75947.1 - 0.14 12.6 0.2 5.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE VCBS PF13517.1 KIA75947.1 - 1.3 9.4 6.8 1.1 9.7 2.1 2.3 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.13 KIA75947.1 - 3.1 7.6 5.4 3 7.7 1.9 2.4 2 0 0 2 2 2 0 Dockerin type I repeat F-box-like PF12937.2 KIA75949.1 - 0.00059 19.4 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KIA75949.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain Nucleo_P87 PF07267.6 KIA75949.1 - 0.042 12.5 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fungal_trans_2 PF11951.3 KIA75950.1 - 1.3e-52 178.6 0.7 1.8e-52 178.2 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75950.1 - 0.00029 20.6 0.7 0.00062 19.6 0.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S24 PF00717.18 KIA75951.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like Aa_trans PF01490.13 KIA75952.1 - 5.3e-35 120.6 31.0 6.1e-35 120.4 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.20 KIA75953.1 - 4.5e-26 91.7 2.3 6.1e-26 91.3 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75953.1 - 2.7e-21 76.4 0.2 3.3e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75953.1 - 9.5e-12 44.9 2.1 5.4e-11 42.4 1.5 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KIA75953.1 - 0.0013 17.7 0.0 0.0045 15.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KIA75953.1 - 0.069 12.9 0.6 0.23 11.2 0.4 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.1 KIA75954.1 - 5.4e-27 95.1 0.0 8.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KIA75954.1 - 2.3e-12 45.8 0.0 5.9e-12 44.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KIA75954.1 - 1.6e-10 40.8 0.0 2.2e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KIA75954.1 - 2.1e-09 36.7 0.1 3.1e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KIA75954.1 - 2.7e-06 26.5 0.3 0.00059 18.8 0.1 3.5 4 2 1 5 5 5 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KIA75954.1 - 7e-05 22.6 0.0 0.013 15.2 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KIA75954.1 - 0.0016 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KIA75954.1 - 0.0039 16.3 0.0 0.033 13.2 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 KIA75954.1 - 0.0079 16.2 0.0 0.26 11.3 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KIA75954.1 - 0.0092 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KIA75954.1 - 0.011 14.7 0.1 0.04 12.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KIA75954.1 - 0.06 12.3 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KIA75955.1 - 7.1e-17 61.4 3.5 6.8e-10 38.5 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KIA75955.1 - 3.7e-06 26.0 1.8 9e-06 24.8 1.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KIA75955.1 - 0.00038 20.4 0.3 0.0013 18.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KIA75955.1 - 0.002 18.5 0.2 0.002 18.5 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KIA75955.1 - 0.0094 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KIA75955.1 - 0.016 15.2 0.0 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 KIA75955.1 - 0.022 14.5 0.1 0.072 12.8 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.10 KIA75955.1 - 0.038 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KIA75955.1 - 0.04 14.3 0.4 0.077 13.4 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KIA75955.1 - 0.052 12.9 0.4 0.084 12.3 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KIA75955.1 - 0.11 12.4 0.3 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KIA75955.1 - 0.15 11.4 0.2 0.28 10.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain WHH PF14414.1 KIA75955.1 - 0.68 9.2 4.1 0.75 9.0 0.0 2.8 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH MFS_1 PF07690.11 KIA75956.1 - 1.6e-39 135.6 56.7 1.9e-39 135.3 36.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KIA75956.1 - 1.1e-23 83.3 22.2 1.4e-23 82.9 15.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KIA75956.1 - 2.7e-16 59.2 14.7 2.7e-16 59.2 10.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Transferase PF02458.10 KIA75957.1 - 1.6e-08 33.4 0.0 2.3e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 Transferase family Fungal_trans PF04082.13 KIA75958.1 - 1.7e-20 72.9 2.2 2.2e-20 72.6 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 KIA75959.1 - 4.6e-71 239.2 0.1 8.3e-71 238.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75959.1 - 3e-32 112.2 0.0 5.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA75959.1 - 1.2e-29 102.5 0.1 2.9e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KIA75959.1 - 3.5e-29 101.4 0.0 5.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KIA75959.1 - 1.3e-13 50.9 0.5 3.2e-13 49.7 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KIA75959.1 - 3e-12 46.8 0.0 7.9e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75959.1 - 2.3e-07 30.5 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KIA75959.1 - 1e-05 25.1 0.0 2.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KIA75959.1 - 8.8e-05 22.9 0.0 0.00025 21.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75959.1 - 0.0002 21.6 0.0 0.00081 19.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75959.1 - 0.00021 21.0 0.0 0.00065 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75959.1 - 0.0077 16.7 0.0 0.042 14.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KIA75959.1 - 0.0084 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KIA75959.1 - 0.02 13.8 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KIA75959.1 - 0.026 14.1 0.8 0.071 12.7 0.6 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 KIA75959.1 - 0.28 10.0 0.0 0.55 9.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KIA75959.1 - 0.57 8.8 0.4 1.3 7.6 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_7 PF13508.1 KIA75960.1 - 3.8e-05 23.7 1.6 0.26 11.4 0.0 4.1 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KIA75960.1 - 6.5e-05 22.8 1.1 1.1 9.2 0.3 4.0 3 1 0 3 3 3 2 Acetyltransferase (GNAT) family FR47 PF08445.5 KIA75960.1 - 0.032 13.9 0.1 8.9 6.1 0.0 3.0 3 0 0 3 3 3 0 FR47-like protein Peptidase_C58 PF03543.9 KIA75960.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen AA_permease PF00324.16 KIA75962.1 - 5.1e-108 361.4 44.7 6.3e-108 361.1 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KIA75962.1 - 5.7e-32 110.7 47.7 6.9e-32 110.5 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease FAA_hydrolase PF01557.13 KIA75963.1 - 4.4e-43 147.2 0.0 4.7e-25 88.3 0.1 2.5 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 KIA75963.1 - 3.7e-35 121.8 1.0 7.5e-35 120.8 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KIA75963.1 - 5.6e-18 65.0 0.0 1.5e-17 63.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KIA75963.1 - 1.4e-12 47.6 0.0 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Amidohydro_1 PF01979.15 KIA75963.1 - 1.7e-07 31.1 0.6 3.1e-07 30.3 0.4 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KIA75963.1 - 4.2e-06 27.0 6.0 8.1e-06 26.0 4.2 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KIA75963.1 - 1.9e-05 24.4 0.0 6.1e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Thioesterase PF00975.15 KIA75963.1 - 6.2e-05 23.3 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KIA75963.1 - 0.00047 19.6 0.1 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KIA75963.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KIA75963.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_8 PF06259.7 KIA75963.1 - 0.004 16.6 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Ser_hydrolase PF06821.8 KIA75963.1 - 0.0045 16.6 0.0 0.72 9.4 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase BAAT_C PF08840.6 KIA75963.1 - 0.018 14.7 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amidohydro_3 PF07969.6 KIA75963.1 - 0.019 14.1 0.8 0.049 12.8 0.1 2.0 1 1 0 2 2 2 0 Amidohydrolase family Lipase_3 PF01764.20 KIA75963.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 KIA75963.1 - 0.041 12.3 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.11 KIA75963.1 - 0.094 12.1 0.0 14 5.0 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF726 PF05277.7 KIA75963.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TRI12 PF06609.8 KIA75964.1 - 4.6e-51 173.7 19.0 5.8e-51 173.3 13.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KIA75964.1 - 9.2e-28 96.9 39.4 9.2e-28 96.9 27.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA75964.1 - 1.2e-10 40.5 9.8 1.2e-10 40.5 6.8 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter Thioesterase PF00975.15 KIA75964.1 - 0.23 11.6 1.2 0.4 10.8 0.8 1.2 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.13 KIA75965.1 - 4.8e-08 32.1 0.0 1.1e-07 30.9 0.0 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KIA75965.1 - 3.7e-06 26.7 11.8 3.7e-06 26.7 8.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KIA75966.1 - 3.8e-26 91.9 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KIA75966.1 - 2.5e-15 56.9 0.0 3.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KIA75966.1 - 1.6e-09 37.6 0.1 3.3e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA75966.1 - 0.00069 19.1 0.1 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KIA75966.1 - 0.0023 17.9 0.1 0.0041 17.1 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KIA75966.1 - 0.0023 17.6 0.2 0.0041 16.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KIA75966.1 - 0.0043 15.9 0.4 0.0085 15.0 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KIA75966.1 - 0.055 13.5 0.2 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KIA75966.1 - 0.13 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NACHT PF05729.7 KIA75967.1 - 4.5e-07 29.6 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KIA75967.1 - 2.9e-05 24.3 0.0 0.00013 22.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KIA75967.1 - 8e-05 22.5 0.0 0.18 12.1 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KIA75967.1 - 0.008 15.9 0.0 9.1 6.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KIA75967.1 - 0.019 15.4 0.0 0.25 11.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_30 PF13604.1 KIA75967.1 - 0.094 12.2 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain LKAAEAR PF15478.1 KIA75968.1 - 0.066 13.4 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif ketoacyl-synt PF00109.21 KIA75969.1 - 7.6e-71 238.5 0.1 2.1e-70 237.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA75969.1 - 1.8e-61 208.2 4.9 2.1e-61 208.0 1.4 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KIA75969.1 - 3.7e-44 151.0 0.2 3.7e-44 151.0 0.2 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 KIA75969.1 - 8e-39 133.1 0.8 8e-39 133.1 0.5 2.5 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.17 KIA75969.1 - 1.9e-34 118.0 0.1 6.2e-34 116.3 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KIA75969.1 - 2.2e-31 109.0 2.2 1.6e-30 106.2 1.5 2.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KIA75969.1 - 3.3e-06 27.2 0.0 1.2e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 KIA75969.1 - 0.013 15.1 0.6 0.037 13.6 0.4 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KIA75969.1 - 0.14 11.1 4.0 0.07 12.0 0.1 2.5 4 0 0 4 4 4 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KIA75970.1 - 1e-72 244.6 0.6 1e-72 244.6 0.4 2.4 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA75970.1 - 3.8e-33 113.8 0.2 8.9e-33 112.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KIA75970.1 - 1.1e-25 90.6 0.1 2.8e-25 89.3 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KIA75970.1 - 1.6e-18 66.7 0.4 3.3e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KIA75970.1 - 3.5e-17 62.6 0.0 1.3e-16 60.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75970.1 - 3.7e-11 42.8 0.0 1.3e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA75970.1 - 7.5e-11 42.0 0.0 3.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75970.1 - 1.7e-08 34.9 0.0 1.2e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75970.1 - 2.3e-08 34.3 0.0 8.8e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KIA75970.1 - 6.4e-06 26.1 0.3 0.00013 22.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 KIA75970.1 - 1.2e-05 24.4 0.5 2.4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KIA75970.1 - 7.3e-05 22.2 0.0 0.00024 20.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 KIA75970.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.7 KIA75970.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KIA75970.1 - 0.015 14.3 0.0 0.044 12.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family UbiA PF01040.13 KIA75971.1 - 3.4e-31 108.3 13.6 5.4e-31 107.7 9.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Fungal_trans_2 PF11951.3 KIA75973.1 - 0.00038 19.1 0.2 0.00088 17.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KIA75974.1 - 5.2e-13 48.7 2.2 5.1e-07 29.0 0.3 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KIA75974.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KIA75974.1 - 0.018 13.9 0.4 0.04 12.8 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KIA75974.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.10 KIA75974.1 - 0.2 9.8 0.1 0.42 8.7 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) ketoacyl-synt PF00109.21 KIA75975.1 - 4.9e-75 252.3 0.0 2.6e-74 249.8 0.0 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA75975.1 - 5.8e-61 205.2 0.3 1.5e-60 203.9 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KIA75975.1 - 2.9e-57 194.4 0.0 4.9e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KIA75975.1 - 7.9e-47 159.2 1.0 3.9e-46 157.0 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KIA75975.1 - 1.4e-46 159.0 0.1 2.7e-46 158.1 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KIA75975.1 - 2.5e-37 127.3 0.6 8.3e-37 125.6 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA75975.1 - 5.7e-13 48.5 0.0 1.5e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA75975.1 - 4.6e-11 43.7 0.0 6.1e-10 40.0 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KIA75975.1 - 3.6e-05 24.1 0.0 8.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KIA75975.1 - 0.00011 22.3 0.0 0.00033 20.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KIA75975.1 - 0.0004 20.1 0.0 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KIA75975.1 - 0.00062 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 KIA75975.1 - 0.0026 16.5 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KIA75975.1 - 0.0064 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KIA75975.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KIA75975.1 - 0.083 12.9 0.7 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 KIA75976.1 - 1.8e-55 188.3 0.0 2.9e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KIA75977.1 - 8.7e-39 133.3 0.0 7.5e-38 130.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 KIA75978.1 - 5.2e-24 84.4 0.0 2.2e-16 59.3 0.0 3.0 3 0 0 3 3 3 3 Transferase family p450 PF00067.17 KIA75979.1 - 3.1e-55 187.5 0.0 2.9e-50 171.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 KIA75980.1 - 1.1e-28 99.3 1.1 2.3e-28 98.4 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KIA75981.1 - 1.6e-13 50.0 0.0 5.3e-13 48.2 0.0 1.8 2 1 0 2 2 2 1 Cytochrome P450 Terpene_synth_C PF03936.11 KIA75982.1 - 2.8e-23 82.5 0.6 3.8e-23 82.0 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Methyltransf_2 PF00891.13 KIA75983.1 - 8.3e-19 67.7 0.0 1.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase ApbA PF02558.11 KIA75985.1 - 1.4e-35 121.9 0.1 1.9e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KIA75985.1 - 6.1e-29 100.5 0.0 9.8e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Glyco_hydro_61 PF03443.9 KIA75986.1 - 9.6e-43 146.5 0.0 1.4e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_4 PF01565.18 KIA75987.1 - 1.9e-21 75.9 0.8 4e-21 74.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KIA75987.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like AMP-binding PF00501.23 KIA75990.1 - 1.1e-33 116.2 0.0 2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KIA75990.1 - 1.9e-29 102.3 0.0 3.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KIA75990.1 - 1.1e-11 44.6 0.0 2.9e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KIA75990.1 - 2.7e-05 24.3 0.1 6.2e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 KIA75990.1 - 0.026 14.1 0.6 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 KIA75990.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KIA75990.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_2 PF00891.13 KIA75991.1 - 1.3e-27 96.5 0.0 3.4e-27 95.2 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KIA75991.1 - 6.7e-05 22.6 0.1 0.0002 21.1 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.1 KIA75992.1 - 6e-15 55.3 0.0 8.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA75992.1 - 2.4e-13 50.3 0.0 1.3e-11 44.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA75992.1 - 1.1e-11 45.0 0.1 5.7e-05 23.5 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KIA75992.1 - 5e-11 43.1 0.0 9.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA75992.1 - 6.1e-11 42.1 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KIA75992.1 - 8.4e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA75992.1 - 0.00095 19.4 0.0 0.01 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KIA75992.1 - 0.002 17.2 0.0 0.0039 16.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KIA75992.1 - 0.0045 16.3 0.0 0.2 11.0 0.1 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) SSP160 PF06933.6 KIA75992.1 - 0.014 13.4 4.6 0.018 13.0 3.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PCMT PF01135.14 KIA75992.1 - 0.054 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dicty_REP PF05086.7 KIA75992.1 - 0.1 10.3 1.6 0.12 10.0 1.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_16 PF10294.4 KIA75992.1 - 0.15 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KIA75992.1 - 0.17 10.9 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PEMT PF04191.8 KIA75993.1 - 4.2e-12 46.1 0.3 6e-10 39.1 0.2 2.5 1 1 1 2 2 2 2 Phospholipid methyltransferase ICMT PF04140.9 KIA75993.1 - 1.9e-11 43.9 1.4 4e-09 36.5 0.0 2.7 2 1 0 3 3 3 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KIA75993.1 - 0.00053 18.6 0.1 0.0021 16.6 0.1 2.2 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KIA75993.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) polyprenyl_synt PF00348.12 KIA75995.1 - 9.3e-36 123.0 0.0 1.5e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KIA75995.1 - 5.3e-06 25.8 0.1 0.00019 20.7 0.0 2.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Zn_clus PF00172.13 KIA75995.1 - 2.1e-05 24.3 7.6 3.7e-05 23.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PROL5-SMR PF15621.1 KIA75995.1 - 0.27 11.6 6.6 2.6 8.5 2.5 2.6 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family RTA1 PF04479.8 KIA75996.1 - 8.9e-25 87.4 3.4 1.3e-24 86.9 2.3 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3439 PF11921.3 KIA75996.1 - 0.00015 21.5 5.9 0.00015 21.5 4.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF1145 PF06611.7 KIA75996.1 - 0.027 14.0 2.0 0.098 12.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) AOX PF01786.12 KIA75996.1 - 6 6.2 6.5 0.71 9.2 0.0 2.4 3 1 1 4 4 4 0 Alternative oxidase WSC PF01822.14 KIA75997.1 - 5.8e-12 45.3 6.2 1.1e-11 44.5 4.3 1.5 1 0 0 1 1 1 1 WSC domain NMU PF02070.10 KIA75998.1 - 0.051 13.0 0.7 0.12 11.9 0.5 1.7 1 0 0 1 1 1 0 Neuromedin U p450 PF00067.17 KIA75999.1 - 1.4e-68 231.4 0.0 1.9e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KIA76000.1 - 2.1e-22 79.5 0.0 4.4e-22 78.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KIA76000.1 - 1.5e-10 40.8 0.0 1.1e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KIA76000.1 - 3.8e-10 40.3 0.0 2.6e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KIA76000.1 - 4.4e-08 33.4 0.0 1.2e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KIA76000.1 - 1.9e-06 28.2 0.0 1.7e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KIA76000.1 - 0.0009 18.3 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KIA76000.1 - 0.0032 17.8 0.0 0.0084 16.4 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 KIA76000.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.8 KIA76000.1 - 0.0096 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KIA76000.1 - 0.019 14.0 0.0 1.4 7.9 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 KIA76000.1 - 0.022 14.1 0.0 0.082 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KIA76000.1 - 0.023 14.6 0.0 0.068 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KIA76000.1 - 0.058 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KIA76001.1 - 4.4e-51 173.8 0.0 5.7e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KIA76002.1 - 3.7e-15 55.5 23.9 3.7e-15 55.5 16.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KIA76002.1 - 5.6e-15 55.1 1.9 5.6e-15 55.1 1.3 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 OATP PF03137.15 KIA76002.1 - 0.012 13.6 6.3 0.1 10.6 0.0 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_23 PF13489.1 KIA76003.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KIA76003.1 - 0.012 15.9 0.0 0.032 14.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KIA76003.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KIA76003.1 - 0.023 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KIA76003.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Aldo_ket_red PF00248.16 KIA76004.1 - 2.1e-64 217.1 0.1 2.6e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 KIA76005.1 - 3e-13 49.8 0.6 6.9e-13 48.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) EVC2_like PF12297.3 KIA76005.1 - 0.0084 14.7 1.3 0.011 14.3 0.9 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein bZIP_Maf PF03131.12 KIA76005.1 - 0.037 14.3 3.8 0.061 13.6 2.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Aldo_ket_red PF00248.16 KIA76006.1 - 1.8e-64 217.2 0.0 2.9e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KIA76006.1 - 2.3e-28 98.9 22.4 2.3e-28 98.9 15.6 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3782 PF12644.2 KIA76006.1 - 0.18 11.6 0.3 27 4.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Fungal_trans PF04082.13 KIA76007.1 - 3.4e-22 78.5 0.1 5.9e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gallidermin PF02052.10 KIA76007.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Gallidermin HAD_2 PF13419.1 KIA76008.1 - 4e-33 115.0 0.1 4.9e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DAO PF01266.19 KIA76009.1 - 1.8e-51 175.1 0.2 2.1e-51 174.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KIA76009.1 - 3.2e-05 24.1 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KIA76009.1 - 0.00013 21.9 0.1 0.00034 20.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KIA76009.1 - 0.00017 21.4 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KIA76009.1 - 0.019 13.9 0.0 0.055 12.3 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KIA76009.1 - 0.048 13.5 0.4 0.094 12.5 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KIA76009.1 - 0.069 11.9 0.4 0.098 11.4 0.3 1.5 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KIA76009.1 - 0.07 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AA_permease PF00324.16 KIA76010.1 - 7.1e-95 318.1 31.1 8.6e-95 317.8 21.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KIA76010.1 - 3.2e-26 91.8 33.3 3.8e-26 91.5 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease 2-Hacid_dh_C PF02826.14 KIA76011.1 - 1e-49 168.1 0.5 1.5e-49 167.5 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KIA76011.1 - 2.1e-09 36.9 0.0 2.8e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KIA76011.1 - 4.7e-06 26.5 0.1 7.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 KIA76011.1 - 0.0043 17.1 0.0 0.4 10.8 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HTH_1 PF00126.22 KIA76011.1 - 0.068 12.9 0.0 0.32 10.7 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ketoacyl-synt PF00109.21 KIA76012.1 - 3.7e-68 229.7 0.1 7.1e-68 228.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KIA76012.1 - 1e-49 169.6 0.1 1.9e-49 168.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KIA76012.1 - 1.1e-34 118.8 2.1 2.9e-34 117.4 1.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KIA76012.1 - 5.4e-26 92.2 0.0 1.3e-25 90.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 KIA76012.1 - 1.6e-14 53.7 0.0 3.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KIA76012.1 - 1.1e-10 41.6 0.8 2.5e-10 40.4 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA76012.1 - 0.0047 15.9 0.0 0.0095 14.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ABC_membrane PF00664.18 KIA76013.1 - 2.4e-73 246.9 28.2 2.6e-37 128.7 7.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KIA76013.1 - 5e-69 230.8 0.1 1.3e-34 119.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KIA76013.1 - 2.4e-13 49.8 4.9 0.00028 20.2 0.0 4.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KIA76013.1 - 2.1e-12 47.6 0.0 0.049 13.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KIA76013.1 - 1.3e-10 40.6 0.1 0.00074 18.9 0.1 3.2 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KIA76013.1 - 1e-08 36.0 0.0 0.01 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KIA76013.1 - 1.9e-08 33.3 0.8 0.0036 15.9 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KIA76013.1 - 2.2e-08 33.4 2.1 0.0022 17.1 0.0 3.3 3 1 0 4 4 4 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KIA76013.1 - 2.4e-08 34.2 5.8 0.0029 17.6 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 KIA76013.1 - 4.7e-06 26.5 0.5 0.028 14.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 KIA76013.1 - 1.5e-05 25.1 2.7 0.27 11.4 0.1 3.9 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KIA76013.1 - 1.6e-05 24.8 0.0 0.1 12.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 KIA76013.1 - 2.3e-05 24.1 4.2 0.16 11.9 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KIA76013.1 - 2.6e-05 24.1 0.3 0.046 13.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KIA76013.1 - 3.5e-05 23.3 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 KIA76013.1 - 4.9e-05 22.8 0.3 0.14 11.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KIA76013.1 - 4.9e-05 22.5 0.4 0.12 11.4 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.9 KIA76013.1 - 6.1e-05 22.7 0.7 2 8.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KIA76013.1 - 9.2e-05 22.1 1.2 1.7 8.2 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KIA76013.1 - 0.00012 22.3 0.0 0.62 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KIA76013.1 - 0.00024 20.3 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.18 KIA76013.1 - 0.00025 20.8 0.2 0.13 12.0 0.0 2.9 2 0 0 2 2 2 1 Dynamin family G-alpha PF00503.15 KIA76013.1 - 0.00028 19.6 0.1 0.32 9.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MobB PF03205.9 KIA76013.1 - 0.00035 20.3 0.1 0.56 9.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KIA76013.1 - 0.00048 19.6 4.8 0.81 9.0 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_28 PF13521.1 KIA76013.1 - 0.00051 20.0 0.1 0.84 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KIA76013.1 - 0.0017 18.7 0.1 4.5 7.7 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein DUF815 PF05673.8 KIA76013.1 - 0.0018 17.2 0.0 0.99 8.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 KIA76013.1 - 0.0034 17.7 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KIA76013.1 - 0.0046 16.6 0.1 1.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase IIGP PF05049.8 KIA76013.1 - 0.0091 14.8 0.3 0.32 9.7 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 KIA76013.1 - 0.02 14.4 0.1 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 KIA76013.1 - 0.025 13.6 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pyr_redox_3 PF13738.1 KIA76013.1 - 0.036 14.1 0.0 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_14 PF13173.1 KIA76013.1 - 0.037 13.9 0.0 7.9 6.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain NACHT PF05729.7 KIA76013.1 - 0.041 13.5 0.2 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Septin PF00735.13 KIA76013.1 - 0.047 12.6 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.17 KIA76013.1 - 0.053 13.6 0.0 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.4 KIA76013.1 - 0.073 11.6 0.0 2.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PRK PF00485.13 KIA76013.1 - 0.09 12.3 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 KIA76013.1 - 0.12 11.3 0.0 3.4 6.5 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Pox_A32 PF04665.7 KIA76013.1 - 0.18 11.0 0.2 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein UDPGT PF00201.13 KIA76014.1 - 1.1e-26 93.4 0.0 1.8e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KIA76014.1 - 7.2e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KIA76014.1 - 1.1e-06 28.1 0.0 7.1e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 1 RTA1 PF04479.8 KIA76016.1 - 1.3e-44 152.4 12.4 1.9e-44 151.8 8.6 1.2 1 0 0 1 1 1 1 RTA1 like protein ketoacyl-synt PF00109.21 KIA76017.1 - 1.6e-77 260.4 0.6 3.7e-77 259.2 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KIA76017.1 - 6e-62 208.5 0.7 2.3e-61 206.6 0.5 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KIA76017.1 - 2.5e-57 194.6 0.1 5.7e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KIA76017.1 - 2.1e-47 161.7 0.4 2.4e-46 158.2 0.0 2.6 2 1 1 3 3 3 1 Polyketide synthase dehydratase adh_short PF00106.20 KIA76017.1 - 9.5e-47 159.0 0.8 3.2e-46 157.2 0.5 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KIA76017.1 - 1e-34 118.9 0.2 2.4e-34 117.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KIA76017.1 - 2e-21 75.8 0.0 1.5e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KIA76017.1 - 6e-11 43.3 0.0 4.5e-10 40.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KIA76017.1 - 5.6e-08 32.5 0.4 1.3e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KIA76017.1 - 9.4e-06 25.8 0.0 2.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KIA76017.1 - 8.6e-05 21.6 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KIA76017.1 - 0.0004 19.1 0.0 0.00071 18.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 KIA76017.1 - 0.00073 19.9 0.0 0.003 17.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KIA76017.1 - 0.02 14.5 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KIA76017.1 - 0.026 14.1 0.1 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 KIA76017.1 - 0.028 13.3 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.13 KIA76017.1 - 0.035 13.2 0.0 0.15 11.1 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 KIA76018.1 - 1.6e-47 161.9 27.8 1.6e-47 161.9 19.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KIA76018.1 - 2.8e-09 36.0 13.1 2.8e-09 36.0 9.1 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter DUF791 PF05631.9 KIA76018.1 - 5.3e-05 22.0 2.1 5.3e-05 22.0 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Abhydrolase_3 PF07859.8 KIA76019.1 - 6.2e-61 205.6 0.0 8.3e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KIA76019.1 - 5e-06 26.3 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KIA76019.1 - 2.6e-05 24.2 1.0 6.5e-05 22.9 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA76019.1 - 0.00051 19.3 0.0 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 KIA76019.1 - 0.0011 17.7 0.2 0.0037 16.0 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 KIA76019.1 - 0.016 14.5 0.0 0.07 12.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.4 KIA76019.1 - 0.093 11.9 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2920 PF11144.3 KIA76019.1 - 0.16 10.9 0.0 3.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) adh_short PF00106.20 KIA76020.1 - 3e-13 50.0 0.1 6.7e-13 48.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KIA76020.1 - 3.9e-09 36.4 0.0 5.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KIA76020.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KIA76020.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 KIA76020.1 - 0.044 13.7 0.0 0.97 9.4 0.0 2.7 3 0 0 3 3 3 0 NADH(P)-binding NmrA PF05368.8 KIA76020.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KIA76021.1 - 1.7e-18 66.4 0.0 4.1e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_Tnp_Tc5 PF03221.11 KIA76021.1 - 1e-12 47.6 0.0 2.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 KIA76021.1 - 0.017 15.2 0.1 0.051 13.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Abhydrolase_3 PF07859.8 KIA76022.1 - 5.2e-26 91.5 0.1 6.5e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KIA76022.1 - 2.1e-17 62.8 0.0 3.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KIA76022.1 - 2.6e-05 23.9 0.1 3.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KIA76022.1 - 0.003 16.7 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KIA76022.1 - 0.29 9.7 0.7 1.4 7.5 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Rubrerythrin PF02915.12 KIA76024.1 - 0.59 10.4 4.0 8.5 6.6 2.7 2.3 1 1 0 1 1 1 0 Rubrerythrin IncA PF04156.9 KIA76024.1 - 1.6 8.2 5.0 2.4 7.7 3.5 1.2 1 0 0 1 1 1 0 IncA protein ketoacyl-synt PF00109.21 KIA76026.1 - 2.1e-39 135.5 0.0 3e-29 102.2 0.0 2.3 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KIA76026.1 - 9.4e-39 131.9 0.0 2.7e-38 130.4 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KIA76027.1 - 5.2e-31 108.1 0.8 1.9e-13 50.4 0.0 3.2 1 1 2 3 3 3 3 Acyl transferase domain AP_endonuc_2 PF01261.19 KIA76027.1 - 0.057 12.7 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4576 PF15144.1 KIA76027.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4576)