# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_hydro_71 PF03659.9 GAO81041.1 - 4e-16 58.4 0.1 4.6e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_2_N PF02837.13 GAO81042.1 - 7.2e-29 100.4 4.6 1.2e-28 99.7 1.4 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAO81042.1 - 7.9e-11 42.3 0.3 2.2e-10 40.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAO81042.1 - 1.5e-05 25.1 4.5 0.00077 19.7 0.1 3.5 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Peptidase_S8 PF00082.17 GAO81043.1 - 0.0001 21.5 0.1 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Nodulin_late PF07127.6 GAO81043.1 - 0.061 13.4 2.2 0.17 12.0 1.5 1.8 1 0 0 1 1 1 0 Late nodulin protein Dyp_perox PF04261.7 GAO81046.1 - 2.2e-09 36.5 0.1 4.2e-07 29.0 0.0 3.4 3 1 0 3 3 3 2 Dyp-type peroxidase family DUF1929 PF09118.6 GAO81047.1 - 2.4e-24 85.2 0.0 5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 GAO81047.1 - 2.3e-16 59.7 0.0 5.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.1 GAO81047.1 - 2.4e-15 55.9 1.3 3.2e-07 30.2 0.1 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAO81047.1 - 1e-14 53.7 0.1 2e-08 33.6 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAO81047.1 - 4.1e-14 52.0 7.3 6.2e-07 29.0 0.1 4.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAO81047.1 - 3.5e-10 39.2 0.8 5.7e-07 29.0 0.3 3.9 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.6 GAO81047.1 - 7.1e-09 35.0 0.1 0.00067 18.7 0.1 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 GAO81047.1 - 0.0011 19.1 0.8 0.051 13.7 0.1 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO81047.1 - 0.012 15.5 3.8 4.1 7.4 0.0 4.2 4 0 0 4 4 4 0 Kelch motif PQQ_3 PF13570.1 GAO81047.1 - 0.045 14.0 2.7 2.5 8.4 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain HAD PF12710.2 GAO81048.1 - 1.7e-13 51.1 0.0 2.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAO81048.1 - 0.00039 19.8 0.0 0.00065 19.0 0.0 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 GAO81048.1 - 0.00092 19.4 0.0 0.0027 17.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.18 GAO81048.1 - 0.024 14.1 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Aminotran_4 PF01063.14 GAO81049.1 - 1.6e-36 125.8 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 GAO81049.1 - 0.021 13.3 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Aminotran_3 PF00202.16 GAO81050.1 - 3.5e-85 285.8 0.0 4.3e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Phage_Mu_F PF04233.9 GAO81050.1 - 0.041 14.3 0.0 16 6.0 0.0 3.2 3 0 0 3 3 3 0 Phage Mu protein F like protein Aminotran_1_2 PF00155.16 GAO81050.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II MFS_1 PF07690.11 GAO81051.1 - 6.2e-24 84.3 31.9 6.2e-24 84.3 22.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAO81051.1 - 0.00018 20.0 2.5 0.00018 20.0 1.7 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein RAMP4 PF06624.7 GAO81051.1 - 0.0088 15.5 0.6 0.66 9.5 0.0 3.2 3 0 0 3 3 3 1 Ribosome associated membrane protein RAMP4 DUF1228 PF06779.9 GAO81051.1 - 0.2 11.6 7.5 0.16 11.9 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Hce2 PF14856.1 GAO81052.1 - 2.4e-30 104.2 0.1 3.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TPR_2 PF07719.12 GAO81053.1 - 8.4e-12 44.0 5.0 0.0081 15.9 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAO81053.1 - 3.8e-10 39.2 7.9 0.00059 19.4 0.2 4.1 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 GAO81053.1 - 1.8e-07 31.6 7.0 0.004 17.8 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO81053.1 - 1.2e-06 27.8 3.6 0.19 11.3 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO81053.1 - 2e-05 24.8 5.1 0.22 11.8 0.0 5.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO81053.1 - 5.7e-05 22.9 10.2 0.026 14.4 0.2 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO81053.1 - 0.00012 22.1 6.4 0.46 11.0 0.9 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO81053.1 - 0.0012 18.8 2.9 18 5.8 0.0 5.7 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO81053.1 - 0.0076 16.7 10.1 2.1 9.2 0.1 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAO81053.1 - 0.04 14.2 0.6 0.58 10.5 0.0 3.2 3 0 0 3 3 2 0 Pentatricopeptide repeat domain TPR_8 PF13181.1 GAO81053.1 - 0.055 13.2 2.0 22 5.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAO81053.1 - 0.52 10.2 8.2 9.5 6.3 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat NMO PF03060.10 GAO81055.1 - 8.5e-36 123.7 4.1 1.1e-33 116.8 2.9 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAO81055.1 - 7.7e-05 21.7 0.2 0.0013 17.6 0.2 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO81055.1 - 0.00082 18.3 1.2 0.0012 17.7 0.8 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 GAO81055.1 - 0.0032 16.4 0.5 0.0049 15.8 0.4 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 GAO81055.1 - 0.026 13.3 2.8 0.038 12.8 1.9 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ThiG PF05690.9 GAO81055.1 - 0.088 11.8 0.5 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG adh_short PF00106.20 GAO81057.1 - 6e-18 65.3 0.3 8.3e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81057.1 - 8.1e-08 32.1 0.1 1e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81057.1 - 1.6e-06 28.1 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2779 PF11074.3 GAO81057.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Glyco_hydro_17 PF00332.13 GAO81059.1 - 0.0002 20.4 1.4 0.00038 19.6 1.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 HET-s_218-289 PF11558.3 GAO81059.1 - 0.01 15.8 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 0 Het-s 218-289 Lactamase_B PF00753.22 GAO81060.1 - 1.1e-21 77.4 0.3 1.4e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO81060.1 - 1.9e-07 30.8 0.1 2.9e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO81060.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short PF00106.20 GAO81061.1 - 2.2e-19 69.9 0.2 3.5e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81061.1 - 4.6e-09 36.4 0.0 6.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81061.1 - 3.9e-05 23.4 0.1 9.9e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 KR domain His_Phos_2 PF00328.17 GAO81062.1 - 7.2e-33 114.3 0.0 9.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_11 PF00457.12 GAO81063.1 - 1.2e-79 265.9 25.8 1.4e-79 265.7 17.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 BA14K PF07886.6 GAO81063.1 - 3.4 7.4 6.6 5.6 6.7 0.3 2.6 2 0 0 2 2 2 0 BA14K-like protein Epimerase PF01370.16 GAO81064.1 - 4.2e-13 49.2 0.1 5.5e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81064.1 - 2.4e-11 43.9 0.1 3.6e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81064.1 - 6.7e-07 28.7 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAO81064.1 - 2.9e-05 24.3 0.1 6.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAO81064.1 - 3.3e-05 22.7 0.0 7.9e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 GAO81064.1 - 5.5e-05 22.3 0.2 0.00026 20.1 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 GAO81064.1 - 0.00016 20.6 0.5 0.004 16.1 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein DapB_N PF01113.15 GAO81064.1 - 0.0019 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 GAO81064.1 - 0.0042 17.1 0.1 0.0085 16.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 GAO81064.1 - 0.0098 15.8 1.0 0.032 14.1 0.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_3 PF03447.11 GAO81064.1 - 0.019 15.3 0.1 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_76 PF03663.9 GAO81065.1 - 3.4e-139 464.3 19.7 4.6e-139 463.9 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ABM PF03992.11 GAO81066.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4265 PF14085.1 GAO81066.1 - 0.057 13.1 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) RibD_C PF01872.12 GAO81067.1 - 2.4e-34 118.7 0.0 2.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain UME PF08064.8 GAO81067.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 UME (NUC010) domain XFP_N PF09364.5 GAO81068.1 - 6.9e-181 600.8 0.0 1e-180 600.2 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 GAO81068.1 - 4.1e-87 290.8 0.0 6e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 GAO81068.1 - 2.2e-84 281.5 0.2 6.6e-84 279.9 0.0 1.8 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Glyco_hydro_35 PF01301.14 GAO81069.1 - 9.1e-79 265.0 0.3 1.2e-78 264.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAO81069.1 - 6.5e-65 217.9 0.1 9.6e-65 217.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAO81069.1 - 9.2e-51 170.7 8.6 2.2e-26 92.3 2.4 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAO81069.1 - 6.9e-24 83.0 0.0 1.9e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Dynamin_N PF00350.18 GAO81070.1 - 1.4e-15 57.4 1.1 1.5e-13 50.9 0.0 3.4 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 GAO81070.1 - 1.8e-05 24.6 0.0 0.00049 20.0 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAO81070.1 - 0.00012 22.3 0.0 0.00012 22.3 0.0 2.8 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 GAO81070.1 - 0.00062 18.9 0.0 0.0073 15.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO81070.1 - 0.0043 17.5 0.0 0.016 15.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 GAO81070.1 - 0.006 16.0 0.1 0.066 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Ribosomal_L17 PF01196.14 GAO81070.1 - 0.0096 16.4 0.3 0.074 13.6 0.2 2.6 2 0 0 2 2 2 1 Ribosomal protein L17 FlxA PF14282.1 GAO81070.1 - 0.012 15.5 14.5 0.26 11.2 0.1 4.1 4 0 0 4 4 4 0 FlxA-like protein T2SE PF00437.15 GAO81070.1 - 0.013 14.3 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.8 GAO81070.1 - 0.026 13.3 1.0 0.046 12.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Adeno_IVa2 PF02456.10 GAO81070.1 - 0.053 12.1 0.0 0.17 10.5 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_22 PF13401.1 GAO81070.1 - 0.061 13.4 0.2 1.9 8.6 0.0 3.4 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 GAO81070.1 - 0.11 12.2 18.5 0.31 10.7 2.2 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 GAO81070.1 - 1.1 9.7 9.4 8.7 6.8 1.3 3.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pox_RNA_Pol_19 PF05320.7 GAO81070.1 - 2.5 7.8 11.5 6.2 6.5 6.9 2.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Cutinase PF01083.17 GAO81071.1 - 4.4e-57 192.7 6.9 5.7e-57 192.3 4.8 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 GAO81071.1 - 6.5e-12 44.8 13.8 6.5e-12 44.8 9.5 4.3 4 1 0 4 4 4 1 Fungal cellulose binding domain PE-PPE PF08237.6 GAO81071.1 - 1.6e-05 24.4 1.3 4.9e-05 22.8 0.1 2.2 3 0 0 3 3 3 1 PE-PPE domain Toxin_7 PF05980.7 GAO81071.1 - 0.014 15.3 1.1 0.014 15.3 0.8 3.2 3 1 0 3 3 3 0 Toxin 7 Serglycin PF04360.7 GAO81071.1 - 0.4 10.4 3.7 0.61 9.7 2.6 1.4 1 0 0 1 1 1 0 Serglycin Sugar_tr PF00083.19 GAO81072.1 - 2.8e-102 342.5 35.3 3.3e-102 342.3 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81072.1 - 9.2e-26 90.3 43.6 1.6e-22 79.7 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO81072.1 - 1.3e-05 23.6 6.1 1.3e-05 23.6 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.1 GAO81073.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81073.1 - 1.1e-09 37.8 0.0 3.9e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family F-box-like PF12937.2 GAO81073.1 - 0.0027 17.3 0.1 0.0053 16.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 GAO81073.1 - 0.052 13.5 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 PRANC domain DFP PF04127.10 GAO81073.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF778 PF05608.7 GAO81074.1 - 0.15 12.0 0.1 0.45 10.4 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Glyco_hydro_11 PF00457.12 GAO81075.1 - 3.3e-75 251.4 22.7 4.6e-75 250.9 15.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 RTA1 PF04479.8 GAO81076.1 - 2.5e-08 33.6 4.1 9.3e-08 31.8 2.8 1.8 1 1 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 GAO81076.1 - 5.5 6.7 8.5 1.5 8.5 0.7 2.7 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Oxidored_q2 PF00420.19 GAO81076.1 - 9.1 5.9 8.6 29 4.3 4.1 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Fungal_trans_2 PF11951.3 GAO81077.1 - 4.5e-27 94.6 0.0 5.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3454 PF11936.3 GAO81077.1 - 0.085 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) MARVEL PF01284.18 GAO81078.1 - 3.2e-10 40.0 18.0 3.9e-10 39.7 12.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain H_PPase PF03030.11 GAO81078.1 - 0.0085 14.4 0.1 0.0099 14.1 0.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase AA_permease_2 PF13520.1 GAO81080.1 - 1.5e-27 96.1 33.4 2.2e-27 95.7 23.1 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_30 PF02055.11 GAO81080.1 - 1.1e-21 76.6 0.8 2.7e-13 48.9 0.1 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAO81080.1 - 3.9e-09 35.9 0.2 4.6e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF973 PF06157.6 GAO81080.1 - 0.18 10.7 10.2 0.12 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF973) p450 PF00067.17 GAO81081.1 - 1.3e-53 182.1 0.0 1.8e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 GAO81082.1 - 4e-37 128.3 0.1 5e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAO81082.1 - 0.027 12.9 0.0 0.067 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DAO PF01266.19 GAO81083.1 - 3.5e-11 42.6 0.2 4.1e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Aminotran_4 PF01063.14 GAO81084.1 - 2.3e-39 135.2 0.0 3.3e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 GAO81084.1 - 0.034 12.6 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) SIR2 PF02146.12 GAO81085.1 - 1.7e-52 177.7 0.0 2.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family AAA_33 PF13671.1 GAO81086.1 - 3.4e-20 72.3 0.0 4e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO81086.1 - 1.2e-09 38.5 0.0 1.6e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO81086.1 - 4.5e-09 37.1 0.0 6.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAO81086.1 - 6e-05 22.2 0.0 8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin SKI PF01202.17 GAO81086.1 - 0.00033 20.5 0.0 0.00051 19.9 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase CPT PF07931.7 GAO81086.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein DUF87 PF01935.12 GAO81086.1 - 0.095 12.5 0.1 8.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 GAO81086.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Methyltransf_23 PF13489.1 GAO81087.1 - 2.6e-17 63.0 0.0 3.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81087.1 - 1.2e-10 41.9 0.0 1.1e-09 38.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81087.1 - 1.1e-08 34.7 0.0 1.6e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81087.1 - 1.4e-07 31.8 0.0 4.2e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81087.1 - 3.8e-07 30.4 0.0 5.1e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO81087.1 - 0.00029 20.8 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO81087.1 - 0.0003 20.3 0.0 0.0036 16.8 0.0 2.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 GAO81087.1 - 0.00032 19.8 0.0 0.0015 17.6 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 GAO81087.1 - 0.0012 17.9 0.0 0.029 13.4 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAO81087.1 - 0.0035 17.6 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO81087.1 - 0.0059 15.9 0.0 0.06 12.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 GAO81087.1 - 0.006 16.0 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 GAO81087.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 GAO81087.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 GAO81087.1 - 0.063 12.8 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 GAO81087.1 - 0.076 12.1 0.0 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Aldo_ket_red PF00248.16 GAO81088.1 - 1e-75 254.2 0.0 1.1e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3087 PF11286.3 GAO81089.1 - 0.013 14.7 0.1 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4231 PF14015.1 GAO81089.1 - 0.065 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ninjurin PF04923.7 GAO81089.1 - 0.13 12.0 1.1 0.23 11.2 0.7 1.4 1 1 0 1 1 1 0 Ninjurin DUF4229 PF14012.1 GAO81089.1 - 0.56 10.1 4.3 0.99 9.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) MOSC PF03473.12 GAO81090.1 - 4.4e-06 26.2 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Prefoldin_2 PF01920.15 GAO81091.1 - 0.041 13.6 5.6 0.96 9.2 0.2 4.4 5 0 0 5 5 5 0 Prefoldin subunit Reo_sigmaC PF04582.7 GAO81091.1 - 0.96 8.5 14.5 2.2 7.4 0.1 4.4 5 0 0 5 5 5 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 GAO81091.1 - 1.5 9.1 16.6 20 5.5 0.1 5.9 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.5 GAO81091.1 - 5.9 6.8 24.5 1.6 8.6 3.5 4.9 6 0 0 6 6 6 0 Bacterial type III secretion protein (HrpB7) RelA_SpoT PF04607.12 GAO81092.1 - 4.7e-18 65.2 0.0 8.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins p450 PF00067.17 GAO81093.1 - 8.1e-35 120.2 0.0 1.6e-34 119.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.16 GAO81094.1 - 1.9e-93 313.4 0.0 2.4e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAO81094.1 - 1.6e-26 91.7 1.0 3.4e-26 90.6 0.7 1.6 1 0 0 1 1 1 1 Starch binding domain ADH_N PF08240.7 GAO81095.1 - 1.4e-26 92.3 4.4 1.5e-26 92.2 1.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81095.1 - 1.2e-16 60.4 0.7 2.1e-16 59.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81095.1 - 2.2e-06 28.6 0.2 4.5e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO81095.1 - 0.012 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAO81095.1 - 0.029 14.7 0.1 0.072 13.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N_assoc PF13823.1 GAO81095.1 - 0.042 13.5 0.1 0.092 12.4 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Rad10 PF03834.9 GAO81096.1 - 0.013 15.2 0.4 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF2235 PF09994.4 GAO81097.1 - 9e-71 238.4 0.0 1.1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 GAO81097.1 - 0.0094 15.7 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M28 PF04389.12 GAO81098.1 - 7.4e-34 117.0 0.0 1.3e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAO81098.1 - 3.6e-15 55.4 0.5 8e-15 54.3 0.4 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 GAO81098.1 - 0.028 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Peptidase_M42 PF05343.9 GAO81098.1 - 0.063 12.0 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Cu_amine_oxid PF01179.15 GAO81099.1 - 3.9e-174 579.2 0.5 4.6e-174 578.9 0.4 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAO81099.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAO81099.1 - 0.00029 20.8 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_76 PF03663.9 GAO81100.1 - 4e-152 506.9 20.6 6.2e-152 506.2 14.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAO81100.1 - 0.0046 16.0 10.1 0.027 13.4 0.2 3.1 1 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 GAO81101.1 - 2.1e-14 53.0 0.2 3.3e-13 49.1 0.1 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81101.1 - 4.3e-06 26.5 13.7 7.5e-06 25.7 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 GAO81102.1 - 2.8 7.1 8.6 4.4 6.4 6.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF500 PF04366.7 GAO81104.1 - 1.7e-45 153.4 0.0 3.5e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) UBA PF00627.26 GAO81104.1 - 0.00065 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain PepSY_2 PF13670.1 GAO81104.1 - 0.068 13.0 0.8 0.16 11.8 0.5 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain GST_N_3 PF13417.1 GAO81105.1 - 2.8e-09 37.0 0.0 5.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO81105.1 - 2.1e-07 30.7 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO81105.1 - 3.3e-06 26.8 0.2 1.1e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO81105.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO81105.1 - 0.062 13.2 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 GAO81106.1 - 2.1e-65 221.0 29.4 2.4e-65 220.8 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81106.1 - 3.3e-10 39.2 38.1 1e-09 37.5 21.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO81106.1 - 5.7e-05 21.6 4.7 5.7e-05 21.6 3.2 3.6 2 2 2 5 5 5 2 MFS/sugar transport protein ApbA_C PF08546.6 GAO81107.1 - 2.4e-28 98.6 0.0 3.4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAO81107.1 - 8.3e-17 61.0 1.8 4.8e-16 58.5 1.3 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 GAO81107.1 - 0.06 13.1 2.6 0.097 12.4 1.0 1.9 1 1 1 2 2 2 0 ThiF family adh_short_C2 PF13561.1 GAO81108.1 - 3.6e-24 85.8 0.0 6.5e-24 85.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81108.1 - 7.6e-22 77.9 0.1 6e-21 75.0 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81108.1 - 5.4e-06 26.1 0.1 3.8e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 KR domain Acetyltransf_1 PF00583.19 GAO81109.1 - 7.8e-09 35.4 0.1 2.3e-08 33.9 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO81109.1 - 8.3e-05 22.6 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO81109.1 - 0.043 13.6 0.2 0.24 11.2 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO81109.1 - 0.064 13.0 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_7 PF13508.1 GAO81109.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO81110.1 - 5.6e-38 130.3 0.0 6.6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO81110.1 - 5.7e-05 23.0 0.0 0.00065 19.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO81110.1 - 0.0068 16.5 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Dicty_CAR PF05462.6 GAO81112.1 - 1.2e-11 44.0 15.8 2.7e-10 39.6 8.6 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 GAO81112.1 - 7e-09 35.5 16.3 1.4e-08 34.5 11.3 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 GAO81112.1 - 5.5e-06 25.6 8.2 7.5e-06 25.2 5.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.19 GAO81112.1 - 0.00089 18.4 13.0 0.0015 17.6 9.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4448 PF14610.1 GAO81112.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3671 PF12420.3 GAO81112.1 - 2.8 7.9 14.1 11 6.0 4.9 3.2 3 0 0 3 3 3 0 Protein of unknown function MAAL_C PF07476.6 GAO81113.1 - 2.3e-111 370.6 0.0 2.9e-111 370.3 0.0 1.1 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MAAL_N PF05034.8 GAO81113.1 - 1.5e-38 132.0 0.0 2.5e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase N-terminus MR_MLE_C PF13378.1 GAO81113.1 - 2.6e-11 43.4 0.0 6.8e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like DIOX_N PF14226.1 GAO81114.1 - 4.4e-18 65.8 0.0 8.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO81114.1 - 1.8e-12 47.4 0.0 3.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EBP PF05241.7 GAO81115.1 - 4.8e-62 208.4 11.3 5.9e-62 208.1 7.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Alginate_lyase PF05426.7 GAO81116.1 - 7.2e-84 281.3 0.4 8.7e-84 281.0 0.3 1.1 1 0 0 1 1 1 1 Alginate lyase Alginate_lyase2 PF08787.6 GAO81117.1 - 1e-51 175.9 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.1 GAO81117.1 - 0.00086 19.0 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase PLA2_B PF01735.13 GAO81118.1 - 3.4e-194 645.5 0.3 3.9e-194 645.3 0.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3433 PF11915.3 GAO81119.1 - 2e-31 108.0 25.0 1.1e-17 63.9 3.5 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_hydro_71 PF03659.9 GAO81119.1 - 5.9e-23 80.9 0.0 5.6e-22 77.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Ank_2 PF12796.2 GAO81120.1 - 1.2e-96 317.2 2.1 1.9e-17 63.3 0.1 5.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81120.1 - 7.6e-48 158.0 1.4 4.1e-06 26.3 0.0 9.5 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 GAO81120.1 - 4.5e-43 144.8 2.2 5.4e-11 42.6 0.0 6.9 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81120.1 - 1.1e-42 143.1 3.7 5.3e-08 32.8 0.0 8.9 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81120.1 - 2.3e-36 120.1 0.1 0.0011 19.0 0.0 9.8 10 0 0 10 10 10 8 Ankyrin repeat FAD_binding_4 PF01565.18 GAO81121.1 - 5.3e-20 71.3 3.2 6.6e-20 71.0 1.6 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO81121.1 - 4.7e-05 23.2 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MBOAT PF03062.14 GAO81122.1 - 0.0018 17.4 2.0 0.0018 17.4 1.4 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family YqhR PF11085.3 GAO81122.1 - 1.8 8.0 6.3 0.2 11.1 1.1 1.9 2 0 0 2 2 2 0 Conserved membrane protein YqhR HTH_psq PF05225.11 GAO81124.1 - 0.16 11.5 1.1 6.2 6.4 0.2 2.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Flavin_Reduct PF01613.13 GAO81125.1 - 4.8e-15 55.7 0.0 9.2e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 GAO81125.1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 GAO81125.1 - 0.00019 21.3 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Acetyltransf_1 PF00583.19 GAO81126.1 - 4.9e-08 32.9 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO81126.1 - 7.9e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO81126.1 - 4e-05 23.7 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO81126.1 - 6.4e-05 22.6 0.0 9.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAO81126.1 - 0.094 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GPI-anchored PF10342.4 GAO81127.1 - 1e-18 67.5 2.7 1e-18 67.5 1.8 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cna_B PF05738.8 GAO81127.1 - 0.049 13.3 0.4 0.049 13.3 0.3 2.6 1 1 1 2 2 2 0 Cna protein B-type domain Pneumo_att_G PF05539.6 GAO81127.1 - 3.4 6.9 21.7 4.3 6.5 15.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DNA_pol_viral_N PF00242.12 GAO81127.1 - 3.8 6.4 11.8 4.2 6.3 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 GAO81127.1 - 4 6.5 8.3 5 6.2 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 GAO81127.1 - 5.1 6.8 8.7 7 6.4 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.7 GAO81127.1 - 8.7 4.8 18.5 9.2 4.8 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein Alpha-amylase PF00128.19 GAO81128.1 - 1.3e-59 202.1 4.3 1.8e-59 201.6 2.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO81128.1 - 3.8e-30 103.8 0.4 8.7e-30 102.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 GAO81129.1 - 7.6e-15 55.1 0.2 1.1e-13 51.2 0.2 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 GAO81129.1 - 2.7e-14 53.2 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 GAO81129.1 - 5.7e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAO81129.1 - 7.8e-06 25.4 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2854 PF11016.3 GAO81129.1 - 0.12 11.8 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) RTA1 PF04479.8 GAO81130.1 - 4.3e-37 127.7 1.8 7.4e-37 127.0 1.3 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4328 PF14219.1 GAO81130.1 - 0.062 12.5 2.6 0.21 10.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Fungal_trans_2 PF11951.3 GAO81131.1 - 5.5e-08 31.8 0.0 7.8e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81131.1 - 2.8e-07 30.3 8.4 4.9e-07 29.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 GAO81132.1 - 3.2e-22 78.9 0.0 6.3e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81132.1 - 2.1e-21 76.1 0.0 3e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAO81132.1 - 3.6e-13 49.7 0.0 1.3e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81132.1 - 2e-11 44.2 0.0 1.3e-05 25.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81132.1 - 1.4e-09 38.5 0.2 2.8e-07 31.0 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81132.1 - 3.1e-09 36.6 0.0 1.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 GAO81132.1 - 2.2e-06 27.6 0.1 8.6e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO81132.1 - 1.1e-05 24.8 0.3 0.033 13.5 0.0 3.1 2 1 1 3 3 3 2 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 GAO81132.1 - 1.2e-05 24.5 0.0 0.059 12.4 0.0 2.6 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family UPF0146 PF03686.8 GAO81132.1 - 0.00041 20.1 0.0 0.00098 18.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) CMAS PF02353.15 GAO81132.1 - 0.001 18.2 0.0 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 GAO81132.1 - 0.0011 18.2 0.1 0.0033 16.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 GAO81132.1 - 0.0015 17.8 0.0 0.057 12.7 0.0 2.5 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 GAO81132.1 - 0.0029 16.9 0.0 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAO81132.1 - 0.0049 16.4 0.1 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 GAO81132.1 - 0.0067 15.4 0.0 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 GAO81132.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.13 GAO81132.1 - 0.011 14.9 1.0 0.32 10.1 0.0 2.9 2 1 1 3 3 3 0 O-methyltransferase Methyltransf_4 PF02390.12 GAO81132.1 - 0.034 13.1 0.0 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_9 PF08003.6 GAO81132.1 - 0.16 10.6 0.0 0.76 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DOT1 PF08123.8 GAO81132.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ras PF00071.17 GAO81133.1 - 0.0027 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Ras family TraI_2 PF07514.6 GAO81134.1 - 0.02 13.6 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative helicase Ank_2 PF12796.2 GAO81135.1 - 1.2e-41 140.9 0.1 8.6e-24 83.7 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81135.1 - 6.7e-28 95.0 0.1 1.2e-12 46.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAO81135.1 - 3.1e-22 78.5 0.1 6.3e-12 45.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81135.1 - 4.6e-22 77.5 1.7 2.8e-15 56.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81135.1 - 1.7e-20 71.0 0.0 1.6e-08 33.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat DUF1993 PF09351.5 GAO81136.1 - 2.5e-60 203.0 0.0 2.8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Bul1_C PF04426.7 GAO81136.1 - 0.04 13.1 0.1 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Bul1 C terminus SASP PF00269.15 GAO81137.1 - 0.094 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type ORC6 PF05460.8 GAO81137.1 - 0.11 11.5 1.6 0.13 11.3 1.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RVT_1 PF00078.22 GAO81138.1 - 1.7e-05 24.2 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phe_tRNA-synt_N PF02912.13 GAO81138.1 - 0.094 12.4 1.9 0.18 11.5 0.3 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain GTPase_Cys_C PF12631.2 GAO81138.1 - 0.1 13.0 0.4 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MFS_1 PF07690.11 GAO81139.1 - 1.6e-36 125.7 9.2 1.6e-36 125.7 6.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAO81139.1 - 0.034 14.1 1.2 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) FMO-like PF00743.14 GAO81140.1 - 1.6e-32 112.4 0.0 2.4e-19 68.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAO81140.1 - 1.5e-17 64.3 0.3 6.9e-17 62.1 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO81140.1 - 2e-11 44.1 0.0 3.2e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO81140.1 - 4.9e-08 32.8 2.6 9.5e-07 28.7 1.8 3.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAO81140.1 - 3.2e-07 30.2 0.1 9.8e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO81140.1 - 4.9e-07 28.9 6.5 0.00011 21.2 3.4 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAO81140.1 - 2.9e-06 26.6 1.7 0.035 13.1 0.7 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 GAO81140.1 - 2.3e-05 23.4 0.0 0.00055 18.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAO81140.1 - 0.00076 19.8 6.8 0.0037 17.6 1.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAO81140.1 - 0.0029 17.3 0.1 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAO81140.1 - 0.003 16.6 0.4 0.0061 15.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAO81140.1 - 0.0058 15.7 1.5 0.012 14.6 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO81140.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO81140.1 - 0.017 13.6 2.7 0.028 12.9 1.5 1.5 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 GAO81140.1 - 0.023 14.1 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 GAO81140.1 - 0.031 14.1 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 GAO81140.1 - 0.075 13.1 1.8 3 7.9 0.5 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 GAO81140.1 - 0.3 9.8 2.0 0.58 8.9 1.4 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 GAO81140.1 - 4.3 6.0 4.4 7.2 5.3 3.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TauD PF02668.11 GAO81141.1 - 2.4e-50 171.6 0.2 3.5e-50 171.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_18 PF12847.2 GAO81142.1 - 0.00013 22.4 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81142.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO81142.1 - 0.046 14.0 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RTA1 PF04479.8 GAO81143.1 - 2.3e-54 184.2 4.8 3.5e-54 183.6 3.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 GAO81144.1 - 7.4e-07 28.9 10.0 1.4e-06 28.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO81144.1 - 0.015 13.9 0.2 0.026 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain NAAA-beta PF15508.1 GAO81145.1 - 5.9e-24 84.2 0.0 2.9e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans PF04082.13 GAO81146.1 - 5.7e-10 38.4 0.7 1e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81146.1 - 3.8e-08 33.0 8.6 6.9e-08 32.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 GAO81147.1 - 2.1e-50 171.9 1.9 3e-50 171.4 1.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3292 PF11696.3 GAO81148.1 - 8.9e-246 816.7 0.5 1.1e-245 816.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF999 PF06198.6 GAO81148.1 - 0.046 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) zf-H2C2_2 PF13465.1 GAO81150.1 - 9.4e-10 38.2 10.9 1.2e-06 28.4 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAO81150.1 - 3.6e-07 30.1 28.0 0.0018 18.5 1.0 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO81150.1 - 1.4 9.4 28.8 0.28 11.5 0.9 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger GATase PF00117.23 GAO81151.1 - 1.2e-40 139.0 0.0 2.2e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 GAO81151.1 - 8.2e-35 118.4 0.0 1.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 GAO81151.1 - 3.8e-10 39.0 0.0 3.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 GAO81151.1 - 4.2e-09 36.1 0.0 8.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 GAO81151.1 - 0.00014 20.5 0.1 0.00059 18.5 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 GAO81151.1 - 0.001 18.4 0.0 0.068 12.4 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 GAO81151.1 - 0.0047 16.4 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 GAO81151.1 - 0.0097 15.4 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 GAO81151.1 - 0.047 12.7 0.1 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 GAO81151.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 GAO81151.1 - 0.073 12.5 0.1 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PP-loop family MFS_1 PF07690.11 GAO81152.1 - 8.4e-49 166.1 35.0 8.4e-49 166.1 24.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81152.1 - 9.6e-07 27.7 32.5 9e-06 24.5 22.5 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF373 PF04123.8 GAO81152.1 - 2.1 7.3 9.5 1.9 7.4 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF373) HsbA PF12296.3 GAO81153.1 - 2e-21 76.1 0.2 2.6e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF2244 PF10003.4 GAO81155.1 - 1.5 8.2 5.7 2 7.7 3.9 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF1469 PF07332.6 GAO81155.1 - 5.4 6.7 7.2 7.7 6.2 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ring_hydroxyl_A PF00848.14 GAO81156.1 - 5.2e-38 130.8 5.0 7.1e-38 130.3 2.5 2.0 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 GAO81156.1 - 1.1e-13 50.5 0.0 2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 GAO81156.1 - 7.3e-09 34.8 2.3 1.9e-08 33.5 1.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 GAO81157.1 - 3.2e-57 193.5 0.0 6.7e-57 192.5 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DAO PF01266.19 GAO81158.1 - 2.2e-56 191.3 0.0 2.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAO81158.1 - 0.00084 19.0 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAO81158.1 - 0.0018 18.3 0.2 0.14 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO81158.1 - 0.0041 16.2 0.1 0.0078 15.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAO81158.1 - 0.0043 16.9 0.9 0.011 15.6 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO81158.1 - 0.013 14.4 4.3 0.88 8.3 3.0 2.1 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.17 GAO81158.1 - 0.015 14.1 0.4 0.029 13.2 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAO81158.1 - 0.021 13.9 0.9 0.032 13.3 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 GAO81158.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 GAO81158.1 - 0.072 13.1 0.6 0.22 11.5 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAO81158.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fil_haemagg_2 PF13332.1 GAO81161.1 - 0.19 11.5 16.7 1.2 8.8 1.8 2.3 2 0 0 2 2 2 0 Haemagluttinin repeat APG6 PF04111.7 GAO81162.1 - 0.087 11.8 1.9 0.37 9.8 0.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 GAO81162.1 - 0.3 10.8 6.9 8.2 6.2 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 GAO81162.1 - 1.6 9.1 5.7 5.4 7.4 4.0 1.9 1 0 0 1 1 1 0 SlyX Mnd1 PF03962.10 GAO81162.1 - 2.6 7.6 7.4 1.2 8.7 3.2 1.8 2 0 0 2 2 2 0 Mnd1 family Ank_2 PF12796.2 GAO81165.1 - 1.2e-42 144.1 0.0 1.2e-12 47.9 0.1 4.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81165.1 - 5.5e-30 101.6 16.6 0.00075 19.1 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 GAO81165.1 - 6e-24 81.7 6.0 0.028 14.6 0.2 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 GAO81165.1 - 3.4e-23 81.1 11.1 0.00063 19.9 0.0 6.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO81165.1 - 1.9e-20 72.7 6.6 2.5e-05 24.6 0.1 5.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.2 GAO81165.1 - 3.8e-05 23.3 0.1 7.4e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81165.1 - 0.00016 21.2 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain CopD PF05425.8 GAO81166.1 - 4 7.7 0.0 4 7.7 0.0 3.4 3 1 0 3 3 3 0 Copper resistance protein D Orai-1 PF07856.7 GAO81166.1 - 5.2 6.5 8.9 0.84 9.1 2.6 2.2 2 1 0 2 2 2 0 Mediator of CRAC channel activity DJ-1_PfpI PF01965.19 GAO81167.1 - 4.4e-25 87.8 0.0 9.7e-25 86.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAO81167.1 - 0.0005 19.5 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 GAO81167.1 - 0.096 12.2 0.1 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Asp PF00026.18 GAO81168.1 - 1.8e-52 178.5 2.3 2.4e-52 178.1 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAO81168.1 - 7.8e-05 22.2 0.1 0.0073 15.8 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAO81168.1 - 0.001 19.5 4.3 0.46 11.0 0.6 4.0 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 GAO81168.1 - 0.12 12.2 0.2 6.6 6.6 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.19 GAO81169.1 - 5.7e-92 308.6 20.7 6.6e-92 308.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81169.1 - 2.6e-19 69.1 25.9 3.7e-19 68.6 18.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAO81169.1 - 0.0024 17.8 4.7 0.27 11.2 0.5 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) adh_short PF00106.20 GAO81171.1 - 1.5e-15 57.5 2.3 2.4e-15 56.8 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81171.1 - 1.2e-11 44.5 1.8 1.9e-11 43.9 1.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81171.1 - 3.3e-06 27.0 0.2 5.2e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cas_Csa4 PF09703.5 GAO81172.1 - 0.032 13.2 0.2 0.044 12.7 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) Acetyltransf_1 PF00583.19 GAO81173.1 - 3.3e-13 49.4 0.0 5.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO81173.1 - 4.1e-09 36.0 0.0 6.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAO81173.1 - 7.3e-08 32.4 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAO81173.1 - 3e-07 30.4 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO81173.1 - 4.2e-07 30.0 0.1 1.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO81173.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO81173.1 - 0.0043 16.9 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 GAO81173.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO81173.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ceramidase PF05875.7 GAO81174.1 - 4.9e-39 134.0 5.2 5.5e-39 133.8 3.6 1.0 1 0 0 1 1 1 1 Ceramidase DUF368 PF04018.8 GAO81174.1 - 0.0098 15.1 2.8 0.013 14.7 1.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF368) Leader_Trp PF08255.6 GAO81174.1 - 0.017 14.7 2.2 0.078 12.6 1.3 2.4 2 0 0 2 2 2 0 Trp-operon Leader Peptide Adeno_E3_CR2 PF02439.10 GAO81174.1 - 0.097 12.2 0.5 0.21 11.1 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Abhydrolase_6 PF12697.2 GAO81175.1 - 2.4e-24 86.4 1.4 3.9e-24 85.8 1.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81175.1 - 6.6e-11 42.2 0.0 1.5e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81175.1 - 1.5e-06 27.9 0.5 3.1e-06 26.9 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAO81175.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Ank_2 PF12796.2 GAO81176.1 - 5.8e-110 359.8 27.8 6e-20 71.3 1.0 9.1 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81176.1 - 6e-69 224.6 46.6 2.4e-07 30.2 0.0 18.6 19 0 0 19 19 19 14 Ankyrin repeat Ank_4 PF13637.1 GAO81176.1 - 6.1e-62 205.0 16.8 4.3e-09 36.6 0.1 13.8 7 6 9 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81176.1 - 4.8e-59 190.4 25.3 8.5e-06 25.5 0.0 18.4 20 0 0 20 20 20 15 Ankyrin repeat Ank_5 PF13857.1 GAO81176.1 - 3.5e-34 116.0 32.3 0.00014 21.9 0.1 15.1 8 5 7 15 15 15 11 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 GAO81176.1 - 0.0091 15.5 0.5 61 2.9 0.0 4.5 3 2 2 5 5 5 0 Shigella flexneri OspC protein Pyr_redox PF00070.22 GAO81177.1 - 6.7e-14 52.0 0.3 8.6e-11 42.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO81177.1 - 4.6e-13 49.4 0.0 2.1e-12 47.3 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO81177.1 - 3e-09 36.8 0.9 0.14 11.8 0.0 4.2 3 1 1 4 4 4 4 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO81177.1 - 4.9e-07 30.0 0.1 0.047 13.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO81177.1 - 0.00014 20.9 0.8 6 5.6 0.0 4.0 4 0 0 4 4 4 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO81177.1 - 0.00018 20.5 2.3 0.04 12.8 0.0 3.0 3 1 1 4 4 4 2 Lycopene cyclase protein K_oxygenase PF13434.1 GAO81177.1 - 0.00031 19.7 1.5 0.43 9.4 0.2 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 GAO81177.1 - 0.0029 17.6 0.3 1.2 9.1 0.0 3.4 3 1 1 4 4 4 1 TrkA-N domain DUF1188 PF06690.6 GAO81177.1 - 0.021 13.9 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.9 GAO81177.1 - 0.1 11.1 0.3 6.9 5.1 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 GAO81177.1 - 0.19 10.1 4.0 11 4.2 0.1 3.5 3 1 1 4 4 4 0 HI0933-like protein Lactamase_B PF00753.22 GAO81180.1 - 5.1e-21 75.2 1.8 1e-20 74.2 1.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fungal_trans PF04082.13 GAO81180.1 - 4e-13 48.8 0.5 6.7e-13 48.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81180.1 - 2.1e-07 30.7 6.1 4.7e-07 29.5 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B_2 PF12706.2 GAO81180.1 - 5e-05 22.9 0.1 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO81180.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 GAO81181.1 - 4.4e-13 49.0 4.2 4.7e-05 22.5 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO81181.1 - 5.9e-06 25.4 0.0 2.4e-05 23.4 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAO81181.1 - 0.00016 20.9 0.0 0.14 11.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO81181.1 - 0.00028 20.8 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO81181.1 - 0.027 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Gly-zipper_Omp PF13488.1 GAO81181.1 - 9.6 5.9 15.7 0.29 10.8 6.0 2.0 2 0 0 2 2 2 0 Glycine zipper ketoacyl-synt PF00109.21 GAO81182.1 - 5.1e-75 252.2 0.0 8.8e-75 251.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO81182.1 - 2.5e-43 148.6 0.0 5.4e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO81182.1 - 2e-33 114.7 0.4 2e-33 114.7 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO81182.1 - 3.9e-13 49.4 0.1 1.2e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO81182.1 - 8e-06 25.0 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAO81182.1 - 0.0058 16.4 0.1 0.22 11.2 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Trp_DMAT PF11991.3 GAO81183.1 - 2.8e-93 312.9 0.0 5.1e-93 312.1 0.0 1.4 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase S-methyl_trans PF02574.11 GAO81184.1 - 2.1e-35 122.5 0.0 4.3e-35 121.4 0.0 1.4 1 1 0 1 1 1 1 Homocysteine S-methyltransferase TIM-br_sig_trns PF09370.5 GAO81184.1 - 0.042 12.9 0.1 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 TIM-barrel signal transduction protein Aldolase_II PF00596.16 GAO81185.1 - 2.3e-49 167.4 0.1 3e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GFA PF04828.9 GAO81186.1 - 2.3e-23 81.9 0.4 3.4e-23 81.4 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_4 PF08386.5 GAO81188.1 - 3.8e-15 55.6 0.0 1.1e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 GAO81188.1 - 2e-07 30.8 4.9 2.3e-06 27.3 2.8 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO81188.1 - 0.019 14.8 0.3 0.27 11.0 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 GAO81189.1 - 7e-18 64.4 46.1 2.1e-08 33.3 17.2 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 GAO81190.1 - 6.1e-11 42.2 0.0 1.2e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81190.1 - 1.1e-09 38.4 0.1 1.6e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81190.1 - 5.7e-07 29.0 0.0 5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAO81190.1 - 0.00023 20.4 0.0 0.0049 16.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAO81190.1 - 0.0088 15.4 0.3 0.012 15.0 0.2 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Fungal_trans PF04082.13 GAO81191.1 - 1.1e-06 27.7 0.0 2.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 GAO81192.1 - 2.3e-31 108.8 0.0 2.1e-30 105.7 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81192.1 - 8.1e-08 32.4 0.4 1.1e-07 32.0 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO81192.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAO81193.1 - 2.1e-35 122.0 24.3 2.1e-35 122.0 16.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_7 PF13508.1 GAO81194.1 - 2.1e-07 31.0 0.0 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO81194.1 - 2.9e-07 30.4 0.5 7.8e-07 29.0 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO81194.1 - 9.1e-07 29.0 0.0 3.5e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO81194.1 - 1.9e-05 24.5 0.0 5.7e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO81194.1 - 0.00056 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAO81194.1 - 0.0061 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase OPT PF03169.10 GAO81195.1 - 1.4e-162 542.3 44.5 5.4e-162 540.4 30.8 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Methyltransf_18 PF12847.2 GAO81196.1 - 6.4e-16 58.9 0.0 5e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81196.1 - 1.4e-12 47.6 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81196.1 - 3.4e-09 36.4 0.0 1.3e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAO81196.1 - 4.1e-08 34.0 0.0 1.4e-07 32.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO81196.1 - 7.7e-07 29.4 0.0 2.2e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81196.1 - 1.5e-06 28.5 0.0 4.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 GAO81196.1 - 1.6e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAO81196.1 - 8.1e-06 25.8 0.1 3.3e-05 23.8 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 GAO81196.1 - 0.00011 21.6 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 GAO81196.1 - 0.00047 20.5 0.1 0.0039 17.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO81196.1 - 0.0022 17.1 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.12 GAO81196.1 - 0.0047 15.8 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_3 PF01596.12 GAO81196.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase AFG1_ATPase PF03969.11 GAO81196.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase CMAS PF02353.15 GAO81196.1 - 0.021 13.9 0.1 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CP12 PF02672.10 GAO81196.1 - 0.044 14.2 0.0 45 4.5 0.0 3.3 3 0 0 3 3 3 0 CP12 domain Methyltransf_4 PF02390.12 GAO81196.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Toxin_31 PF08119.6 GAO81197.1 - 0.055 12.9 6.7 74 2.9 0.0 5.3 6 0 0 6 6 6 0 Scorpion acidic alpha-KTx toxin family DUF3914 PF13053.1 GAO81197.1 - 0.33 11.1 5.0 36 4.6 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3914) XAP5 PF04921.9 GAO81197.1 - 0.57 9.7 6.0 13 5.2 0.4 2.6 1 1 1 2 2 2 0 XAP5, circadian clock regulator DUF3328 PF11807.3 GAO81198.1 - 5.3e-58 196.2 2.0 6.6e-58 195.9 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.22 GAO81199.1 - 4.7e-90 298.9 0.0 3.8e-31 108.2 0.0 4.5 4 0 0 4 4 4 4 ABC transporter ABC2_membrane PF01061.19 GAO81199.1 - 2.9e-88 294.5 48.9 1.7e-49 167.8 16.2 4.3 5 0 0 5 5 2 2 ABC-2 type transporter ABC_membrane PF00664.18 GAO81199.1 - 6.9e-35 120.7 39.6 8.6e-22 77.8 7.2 4.5 4 0 0 4 4 4 2 ABC transporter transmembrane region PDR_CDR PF06422.7 GAO81199.1 - 2.1e-27 94.7 0.0 2.1e-27 94.7 0.0 2.8 3 0 0 3 3 2 1 CDR ABC transporter AAA_25 PF13481.1 GAO81199.1 - 6.8e-13 48.4 1.3 0.015 14.7 0.1 4.9 4 1 0 4 4 4 3 AAA domain AAA_21 PF13304.1 GAO81199.1 - 3.1e-12 47.0 0.1 0.87 9.4 0.0 6.6 7 0 0 7 7 7 3 AAA domain ABC2_membrane_3 PF12698.2 GAO81199.1 - 2.1e-11 43.4 37.6 2.5e-08 33.3 14.9 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 GAO81199.1 - 1e-10 41.2 1.7 0.067 12.4 0.0 6.1 5 2 0 6 6 6 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAO81199.1 - 1.6e-09 38.0 1.3 0.71 10.0 0.0 5.8 4 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAO81199.1 - 2.4e-08 33.3 3.8 0.21 11.1 0.2 4.6 4 0 0 4 4 4 3 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO81199.1 - 1.7e-07 31.4 10.2 0.22 11.4 0.1 4.8 4 1 0 4 4 4 3 AAA ATPase domain DUF258 PF03193.11 GAO81199.1 - 3.4e-07 29.5 0.4 0.043 13.0 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAO81199.1 - 1.1e-06 29.5 1.7 3.5 8.4 0.0 4.7 4 0 0 4 4 4 0 AAA domain ABC_trans_N PF14510.1 GAO81199.1 - 2e-06 27.7 0.1 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_10 PF12846.2 GAO81199.1 - 2.1e-05 24.1 5.2 3 7.1 0.0 5.2 5 0 0 5 5 5 1 AAA-like domain SbcCD_C PF13558.1 GAO81199.1 - 4.3e-05 23.3 0.0 3.9 7.4 0.0 4.4 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 GAO81199.1 - 4.4e-05 23.4 0.2 0.37 10.7 0.0 4.3 4 0 0 4 4 4 1 50S ribosome-binding GTPase AAA_23 PF13476.1 GAO81199.1 - 4.4e-05 23.8 3.2 0.1 12.9 0.2 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 GAO81199.1 - 5.8e-05 22.7 3.2 0.59 9.9 0.1 4.3 4 0 0 4 4 4 1 Part of AAA domain Miro PF08477.8 GAO81199.1 - 8.2e-05 23.0 0.8 7.2 7.1 0.0 4.2 4 0 0 4 4 3 0 Miro-like protein cobW PF02492.14 GAO81199.1 - 0.00012 21.6 6.5 0.72 9.2 0.1 4.2 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 GAO81199.1 - 0.00042 20.6 4.4 5.6 7.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 GAO81199.1 - 0.00047 19.8 7.5 0.62 9.7 0.2 4.4 4 0 0 4 4 4 1 NACHT domain FtsK_SpoIIIE PF01580.13 GAO81199.1 - 0.00065 19.2 0.2 6.2 6.2 0.0 4.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 GAO81199.1 - 0.00074 19.0 5.0 1.1 8.7 0.0 4.0 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 GAO81199.1 - 0.0012 18.7 2.0 2.8 7.8 0.0 4.4 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 GAO81199.1 - 0.0019 17.1 1.6 3.3 6.5 0.1 3.9 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA PF00004.24 GAO81199.1 - 0.0023 18.1 0.1 68 3.6 0.0 4.8 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAO81199.1 - 0.013 15.2 2.8 14 5.3 0.0 4.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 GAO81199.1 - 0.023 14.3 4.0 13 5.4 0.1 4.1 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAO81199.1 - 0.043 13.4 3.7 29 4.1 0.1 4.7 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.17 GAO81199.1 - 0.048 13.8 1.1 1e+02 3.1 0.0 4.3 4 0 0 4 4 4 0 RNA helicase Dynamin_N PF00350.18 GAO81199.1 - 0.053 13.3 0.5 4.8 6.9 0.0 2.9 3 0 0 3 3 2 0 Dynamin family DUF2075 PF09848.4 GAO81199.1 - 0.073 12.0 1.3 0.43 9.5 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 GAO81199.1 - 0.073 12.5 0.3 19 4.6 0.0 3.6 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 GAO81199.1 - 0.075 12.9 8.2 0.92 9.4 0.3 4.0 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 GAO81199.1 - 0.078 12.0 0.0 4.7 6.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 GAO81199.1 - 0.082 12.5 1.2 63 3.1 0.0 3.7 4 0 0 4 4 3 0 Archaeal ATPase Zeta_toxin PF06414.7 GAO81199.1 - 0.18 10.9 3.4 22 4.0 0.1 3.7 4 0 0 4 4 4 0 Zeta toxin ArgK PF03308.11 GAO81199.1 - 0.25 10.0 0.4 5.5 5.6 0.0 2.5 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 GAO81199.1 - 0.25 11.1 8.6 0.57 9.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF2024 PF09630.5 GAO81199.1 - 0.33 10.6 0.1 0.82 9.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) NTPase_1 PF03266.10 GAO81199.1 - 0.81 9.3 3.2 37 3.9 0.1 4.3 6 0 0 6 6 5 0 NTPase Pox_A32 PF04665.7 GAO81199.1 - 1.5 8.0 6.3 5.3 6.2 0.2 3.5 4 0 0 4 4 4 0 Poxvirus A32 protein AAA_24 PF13479.1 GAO81199.1 - 1.7 8.1 4.0 58 3.1 0.1 3.7 4 0 0 4 4 4 0 AAA domain CbiA PF01656.18 GAO81199.1 - 4.7 6.5 3.1 26 4.1 0.2 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 GAO81199.1 - 9 6.0 5.8 69 3.1 0.0 4.2 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) ketoacyl-synt PF00109.21 GAO81200.1 - 4.4e-78 262.2 0.0 9.2e-78 261.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAO81200.1 - 1.3e-63 213.9 0.3 6.9e-62 208.3 0.1 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAO81200.1 - 4.2e-62 209.9 0.0 1.3e-61 208.4 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 GAO81200.1 - 1.4e-51 174.7 1.0 4.2e-48 163.4 0.1 3.0 2 0 0 2 2 2 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 GAO81200.1 - 8.6e-51 173.1 0.5 6e-49 167.0 0.0 2.6 2 1 1 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO81200.1 - 2.1e-38 130.8 0.1 1.6e-37 127.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 GAO81200.1 - 7.8e-07 28.7 0.0 0.017 14.5 0.0 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO81200.1 - 1e-06 28.9 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAO81200.1 - 2e-06 27.6 0.0 2.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81200.1 - 5.9e-05 22.6 0.0 0.0018 17.9 0.0 3.1 4 0 0 4 4 3 1 Methyltransferase domain Thiolase_N PF00108.18 GAO81200.1 - 0.00027 20.0 0.2 0.00062 18.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 GAO81200.1 - 0.00045 20.6 0.1 0.0021 18.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 GAO81200.1 - 0.00053 20.0 0.5 0.0086 16.0 0.0 2.8 3 0 0 3 3 2 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO81200.1 - 0.00055 19.0 2.5 0.12 11.3 0.1 3.1 3 0 0 3 3 3 1 Saccharopine dehydrogenase Methyltransf_11 PF08241.7 GAO81200.1 - 0.0006 20.2 0.0 0.0025 18.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 GAO81200.1 - 0.0013 18.0 4.2 0.24 10.6 0.1 3.1 4 0 0 4 4 4 2 NmrA-like family ADH_N PF08240.7 GAO81200.1 - 0.0063 16.2 0.0 0.035 13.8 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 GAO81200.1 - 0.0069 16.9 0.0 3.2 8.3 0.0 3.5 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox PF00070.22 GAO81200.1 - 0.038 14.3 0.1 10 6.6 0.1 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 GAO81200.1 - 0.046 12.6 0.0 6.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.13 GAO81200.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.13 GAO81200.1 - 0.13 11.9 1.0 6.8 6.3 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FSH1 PF03959.8 GAO81201.1 - 1.2e-28 99.9 0.0 1.5e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAO81201.1 - 0.00095 19.1 0.0 0.098 12.5 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81201.1 - 0.013 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family TspO_MBR PF03073.10 GAO81202.1 - 1.9e-46 157.2 16.1 2.2e-46 157.0 11.1 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1212 PF06738.7 GAO81203.1 - 3.5e-54 183.1 13.9 3.6e-50 170.1 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAO81203.1 - 1.6e-29 102.4 6.6 1.6e-29 102.4 4.6 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Transket_pyr PF02779.19 GAO81204.1 - 3.7e-44 150.3 0.2 5.6e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAO81204.1 - 4.2e-31 107.4 0.1 1.1e-30 106.1 0.1 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_3 PF01494.14 GAO81205.1 - 1.1e-14 54.3 3.3 4.9e-12 45.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO81205.1 - 3.5e-05 22.8 1.9 0.0061 15.5 0.2 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81205.1 - 6.3e-05 22.9 0.1 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO81205.1 - 0.00091 19.5 1.1 0.028 14.8 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO81205.1 - 0.0023 17.7 0.3 0.15 11.8 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 GAO81205.1 - 0.0035 16.1 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 GAO81205.1 - 0.013 15.3 0.1 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO81205.1 - 0.026 13.5 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 GAO81205.1 - 0.095 11.5 0.2 2.2 7.0 0.2 2.1 1 1 1 2 2 2 0 Glucose inhibited division protein A DUF1254 PF06863.7 GAO81206.1 - 0.0069 16.2 0.1 0.042 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) BNR PF02012.15 GAO81206.1 - 0.092 12.6 4.1 0.24 11.3 0.4 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Arylsulfotran_2 PF14269.1 GAO81207.1 - 4.9e-60 203.2 2.0 7.9e-60 202.5 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) ADH_N PF08240.7 GAO81207.1 - 3.7e-30 103.8 0.9 7.7e-30 102.8 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arylsulfotrans PF05935.6 GAO81207.1 - 7.1e-15 54.4 4.5 2.2e-14 52.8 3.1 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) ADH_zinc_N PF00107.21 GAO81207.1 - 4.6e-11 42.3 0.1 1.1e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 GAO81207.1 - 0.02 14.9 0.1 0.068 13.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 GAO81208.1 - 1.4e-64 217.6 0.0 1.6e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_psq PF05225.11 GAO81208.1 - 0.025 14.0 1.3 15 5.2 0.0 4.3 4 0 0 4 4 4 0 helix-turn-helix, Psq domain p450 PF00067.17 GAO81209.1 - 7.7e-10 37.8 0.0 6.7e-08 31.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_10 PF13673.1 GAO81210.1 - 1.6e-08 34.6 0.1 6e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO81210.1 - 1.7e-07 31.3 0.0 3.7e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO81210.1 - 3.1e-07 30.3 0.1 6.1e-07 29.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO81210.1 - 0.00045 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAO81210.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAO81210.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 GAO81211.1 - 2.1e-41 140.1 0.4 3.1e-21 75.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81211.1 - 1.4e-36 122.5 0.1 8.9e-09 34.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 GAO81211.1 - 1.1e-33 111.9 0.0 3.5e-07 29.8 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAO81211.1 - 1.3e-30 104.7 3.8 2.7e-10 40.1 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO81211.1 - 2.7e-27 94.6 1.8 4.1e-10 39.8 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAO81211.1 - 4.5e-10 38.9 0.5 7.9e-09 34.8 0.4 2.5 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO81211.1 - 2.9e-08 33.5 0.0 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAO81211.1 - 0.0086 16.2 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO81211.1 - 0.019 14.9 0.3 0.16 11.9 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF1129 PF06570.6 GAO81212.1 - 0.043 13.1 1.4 0.061 12.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7tm_1 PF00001.16 GAO81212.1 - 8.1 5.4 9.8 1.6 7.8 3.3 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Fungal_trans PF04082.13 GAO81213.1 - 2.2e-20 72.6 0.0 4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81213.1 - 4.3e-08 32.9 15.2 4.3e-08 32.9 10.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M30 PF10460.4 GAO81213.1 - 0.091 11.6 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 Dickkopf_N PF04706.7 GAO81213.1 - 0.95 9.6 14.6 2.4 8.4 10.1 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 GAO81214.1 - 4.4e-47 160.5 41.9 1e-46 159.2 29.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81214.1 - 6.8e-13 47.6 21.2 1.4e-12 46.6 14.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4407 PF14362.1 GAO81214.1 - 0.14 11.0 0.1 0.14 11.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Phosphoesterase PF04185.9 GAO81215.1 - 7.6e-74 249.1 0.5 1.9e-73 247.8 0.3 1.6 1 1 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.11 GAO81216.1 - 3.3e-27 95.1 66.7 2.7e-19 69.0 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 GAO81217.1 - 5.6e-132 440.4 48.5 6.8e-132 440.1 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO81217.1 - 1.9e-35 122.2 55.4 2.4e-35 121.8 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease Angiomotin_C PF12240.3 GAO81217.1 - 0.13 11.7 0.6 0.19 11.2 0.4 1.1 1 0 0 1 1 1 0 Angiomotin C terminal DUF2207 PF09972.4 GAO81217.1 - 4.4 5.7 0.0 4.4 5.7 0.0 3.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.14 GAO81218.1 - 3.9e-65 219.9 0.0 5.3e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO81218.1 - 6.7e-39 133.4 0.0 1.1e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO81218.1 - 1.4e-07 30.7 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO81218.1 - 3.9e-05 22.7 4.0 0.0057 15.6 1.2 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO81218.1 - 0.0029 17.9 0.2 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO81218.1 - 0.0042 17.0 0.1 0.016 15.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAO81218.1 - 0.0074 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAO81218.1 - 0.051 12.6 0.2 0.17 10.9 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 GAO81218.1 - 0.074 13.1 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO81218.1 - 0.11 10.8 0.0 0.38 9.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF4293 PF14126.1 GAO81219.1 - 1.2 9.0 8.1 0.082 12.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) FAD_binding_3 PF01494.14 GAO81220.1 - 2.7e-16 59.5 2.2 4.3e-15 55.6 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO81220.1 - 7.4e-13 48.1 3.3 3.4e-06 26.2 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81220.1 - 2.4e-07 30.6 1.4 5.4e-07 29.5 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO81220.1 - 5e-07 29.7 2.9 7.4e-06 25.9 2.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO81220.1 - 7e-06 25.1 4.7 8.9e-06 24.8 1.6 2.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 GAO81220.1 - 1.8e-05 25.0 0.8 4.2e-05 23.8 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO81220.1 - 6.1e-05 22.2 0.5 9.5e-05 21.6 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO81220.1 - 0.00019 20.4 1.7 0.00021 20.2 0.5 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAO81220.1 - 0.00033 19.2 1.2 0.00033 19.2 0.8 1.4 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 GAO81220.1 - 0.0019 16.9 1.3 0.023 13.3 0.5 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 GAO81220.1 - 0.0019 17.3 0.2 0.0037 16.4 0.2 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAO81220.1 - 0.0022 17.7 1.3 0.66 9.7 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 GAO81220.1 - 0.0037 16.4 1.5 0.057 12.4 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAO81220.1 - 0.0045 17.0 0.4 0.019 15.0 0.3 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO81220.1 - 0.0062 16.1 1.0 0.016 14.7 0.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAO81220.1 - 0.022 13.6 1.1 0.83 8.5 0.2 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 GAO81220.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_2 PF12796.2 GAO81221.1 - 8.7e-13 48.4 0.2 7.7e-06 26.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81221.1 - 4e-08 33.5 0.5 0.028 14.9 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81221.1 - 2.2e-07 30.8 0.1 0.00039 20.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAO81221.1 - 1.4e-06 27.8 0.2 0.00033 20.3 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 GAO81221.1 - 3.6e-05 23.6 0.0 0.015 15.4 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Acetyltransf_1 PF00583.19 GAO81222.1 - 0.0001 22.2 0.0 0.00031 20.7 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO81222.1 - 0.00058 19.9 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO81222.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Death PF00531.17 GAO81222.1 - 0.084 12.6 0.9 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Death domain PAD_porph PF04371.10 GAO81223.1 - 7.6e-64 215.8 0.0 1.1e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase MFS_1 PF07690.11 GAO81223.1 - 1e-29 103.3 30.7 1e-29 103.3 21.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.1 GAO81224.1 - 2.4e-34 118.5 48.0 3e-34 118.2 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO81224.1 - 4.2e-17 61.6 39.8 6.1e-17 61.1 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease Chromate_transp PF02417.10 GAO81225.1 - 1.3e-59 200.5 34.0 1e-32 113.0 6.3 2.7 2 1 0 2 2 2 2 Chromate transporter C_GCAxxG_C_C PF09719.5 GAO81225.1 - 0.03 14.1 1.5 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Dioxygenase_C PF00775.16 GAO81227.1 - 6.5e-13 48.3 0.4 1e-12 47.6 0.3 1.3 1 0 0 1 1 1 1 Dioxygenase ADH_zinc_N PF00107.21 GAO81228.1 - 1.7e-25 89.0 1.6 1.8e-24 85.7 0.6 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81228.1 - 4.7e-22 77.8 0.2 1e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 GAO81228.1 - 8e-11 41.6 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N_2 PF13602.1 GAO81228.1 - 2.1e-09 38.3 0.1 0.00035 21.4 0.0 2.7 2 0 0 2 2 2 2 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAO81228.1 - 3.4e-06 27.1 0.3 0.00083 19.4 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 GAO81228.1 - 0.0034 17.2 0.0 3.7 7.4 0.1 2.6 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 GAO81228.1 - 0.0053 16.7 0.6 10 5.9 1.5 3.1 2 1 1 3 3 3 1 short chain dehydrogenase TrkA_N PF02254.13 GAO81228.1 - 0.032 14.2 0.3 0.074 13.0 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 GAO81228.1 - 0.067 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO81228.1 - 0.078 12.5 0.8 0.15 11.6 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 GAO81228.1 - 0.15 12.1 0.1 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 GAO81229.1 - 4.8e-13 49.5 1.1 7.7e-13 48.8 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81229.1 - 1.2e-10 41.2 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81229.1 - 6.4e-05 22.6 0.0 0.00012 21.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAO81229.1 - 8.4e-05 22.2 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAO81229.1 - 0.00031 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_4 PF08386.5 GAO81229.1 - 0.0018 18.1 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 1 TAP-like protein DUF1749 PF08538.5 GAO81229.1 - 0.024 13.5 0.0 0.067 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Zn_clus PF00172.13 GAO81230.1 - 1.7e-07 31.0 5.8 3.1e-07 30.1 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 GAO81231.1 - 1.2e-89 300.6 0.0 1.8e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAO81231.1 - 3.5e-78 262.6 1.0 5.7e-78 261.9 0.1 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAO81231.1 - 2.1e-60 204.4 0.3 3.7e-60 203.6 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAO81231.1 - 1.1e-57 194.5 0.9 2.1e-56 190.4 0.2 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAO81231.1 - 1.7e-50 172.1 0.1 3.9e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAO81231.1 - 6e-50 169.4 1.5 8.3e-46 155.9 0.1 3.0 2 0 0 2 2 2 2 short chain dehydrogenase Condensation PF00668.15 GAO81231.1 - 9.4e-50 169.1 0.1 1.6e-49 168.4 0.1 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 GAO81231.1 - 3.1e-44 150.7 0.0 2e-43 148.1 0.0 2.4 3 0 0 3 3 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAO81231.1 - 4.6e-30 103.9 0.1 1e-28 99.5 0.0 3.0 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO81231.1 - 1.1e-18 67.5 0.0 2.9e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 GAO81231.1 - 2e-18 66.6 0.0 9.8e-16 57.9 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO81231.1 - 5.9e-18 64.8 0.0 4.2e-08 33.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO81231.1 - 2.4e-13 50.2 0.3 9.4e-13 48.2 0.1 2.1 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 GAO81231.1 - 7.2e-13 48.8 0.0 2.3e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81231.1 - 1.2e-12 47.8 0.0 3.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81231.1 - 2.3e-12 46.7 0.0 5.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81231.1 - 4.4e-09 36.9 0.0 4.7e-08 33.6 0.0 3.0 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO81231.1 - 1.1e-07 31.2 0.0 3.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAO81231.1 - 5.7e-07 29.8 0.0 3.7e-06 27.2 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO81231.1 - 6e-06 25.4 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 GAO81231.1 - 3.5e-05 22.6 0.0 0.0015 17.2 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 GAO81231.1 - 7.3e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 GAO81231.1 - 0.0017 17.4 0.0 0.017 14.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 GAO81231.1 - 0.044 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Transferase PF02458.10 GAO81231.1 - 0.92 7.8 0.0 1.4 7.2 0.0 1.2 1 0 0 1 1 1 0 Transferase family DUF2884 PF11101.3 GAO81231.1 - 1.2 8.4 0.1 2.7 7.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Polysacc_synt_2 PF02719.10 GAO81231.1 - 2.6 6.8 0.0 13 4.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AATase PF07247.7 GAO81231.1 - 2.7 6.4 0.1 4.1 5.8 0.1 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Abhydrolase_5 PF12695.2 GAO81232.1 - 1.9e-12 47.1 0.0 1.9e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81232.1 - 1.6e-10 41.2 1.5 1.9e-10 41.0 0.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO81232.1 - 5.2e-06 26.0 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase DUF1100 PF06500.6 GAO81232.1 - 0.0001 21.0 0.0 0.00014 20.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAO81232.1 - 0.00015 21.0 0.3 0.001 18.3 0.1 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAO81232.1 - 0.027 14.0 0.1 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAO81232.1 - 0.037 13.6 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAO81232.1 - 0.043 13.6 0.1 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 GAO81232.1 - 0.16 11.3 0.1 0.39 10.1 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase GST_N PF02798.15 GAO81233.1 - 1.9e-09 37.5 0.0 4.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO81233.1 - 2.4e-09 37.0 0.0 3.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO81233.1 - 3.8e-07 29.8 0.4 7.4e-07 28.9 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO81233.1 - 1.5e-05 25.0 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO81233.1 - 2.3e-05 24.8 0.3 3.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO81233.1 - 0.00065 19.6 0.0 0.0029 17.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 GAO81234.1 - 5e-87 292.3 0.0 5.9e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAO81235.1 - 2.6e-45 154.6 52.9 4.4e-44 150.6 36.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81235.1 - 4.2e-16 58.2 16.8 6.7e-16 57.5 11.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO81235.1 - 4.6e-14 51.8 12.8 4.6e-14 51.8 8.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Phage_holin_3 PF05106.7 GAO81235.1 - 0.023 14.6 0.9 0.16 11.9 0.6 2.5 1 1 0 1 1 1 0 Phage holin family (Lysis protein S) zf-LITAF-like PF10601.4 GAO81235.1 - 5.4 6.9 7.3 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Methyltransf_7 PF03492.10 GAO81236.1 - 1.5e-25 89.6 0.1 3.9e-25 88.3 0.1 1.6 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Asp PF00026.18 GAO81237.1 - 5.9e-20 71.7 0.0 9.6e-20 71.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAO81237.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Aldedh PF00171.17 GAO81238.1 - 6.8e-135 449.9 0.0 8.2e-135 449.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO81238.1 - 0.00078 18.2 0.0 0.011 14.4 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ABC_tran PF00005.22 GAO81239.1 - 1.9e-50 170.7 0.0 4.3e-28 98.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO81239.1 - 4.8e-36 124.5 29.2 2.5e-24 86.1 6.7 3.2 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO81239.1 - 6.1e-14 51.7 3.5 7.2e-05 22.1 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO81239.1 - 1.2e-10 41.8 1.5 0.061 13.2 0.1 4.1 3 1 0 4 4 4 3 AAA domain Dicty_CAR PF05462.6 GAO81239.1 - 4.9e-09 35.5 9.8 4.9e-09 35.5 6.8 2.7 3 0 0 3 3 2 1 Slime mold cyclic AMP receptor AAA_16 PF13191.1 GAO81239.1 - 4.1e-08 33.4 0.2 0.0024 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Git3 PF11710.3 GAO81239.1 - 3.6e-07 29.9 11.0 3.6e-07 29.9 7.7 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 AAA_23 PF13476.1 GAO81239.1 - 1e-06 29.2 0.1 0.022 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO81239.1 - 2.4e-06 26.8 0.2 0.0067 15.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAO81239.1 - 2.5e-06 26.9 0.1 0.09 12.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAO81239.1 - 4.7e-06 27.1 0.2 0.014 15.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAO81239.1 - 5.2e-06 26.3 0.0 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO81239.1 - 3.5e-05 23.6 0.2 0.015 15.1 0.0 2.6 3 0 0 3 3 2 1 Dynamin family T2SE PF00437.15 GAO81239.1 - 3.7e-05 22.7 0.1 0.051 12.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 GAO81239.1 - 8.9e-05 21.9 0.0 0.21 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO81239.1 - 0.0002 21.4 0.4 0.8 9.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 GAO81239.1 - 0.00022 22.0 0.1 0.7 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 GAO81239.1 - 0.0012 19.1 0.0 0.061 13.5 0.0 2.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAO81239.1 - 0.0016 18.7 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 GAO81239.1 - 0.0021 16.7 4.0 1.3 7.5 0.1 3.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 GAO81239.1 - 0.0042 16.8 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 GAO81239.1 - 0.0049 16.3 2.1 0.11 11.9 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 GAO81239.1 - 0.0061 16.1 0.4 8.6 5.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 GAO81239.1 - 0.0076 15.9 1.2 0.88 9.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAO81239.1 - 0.0078 15.6 1.5 1.4 8.2 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 GAO81239.1 - 0.01 15.5 0.1 0.48 10.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 GAO81239.1 - 0.019 14.0 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 GAO81239.1 - 0.021 14.5 0.9 5.4 6.7 0.0 3.1 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 GAO81239.1 - 0.022 14.9 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 GAO81239.1 - 0.022 14.6 0.0 1.3 8.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain UreE_N PF02814.10 GAO81239.1 - 0.032 13.7 0.3 3 7.4 0.0 3.2 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain FtsK_SpoIIIE PF01580.13 GAO81239.1 - 0.038 13.4 0.7 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 GAO81239.1 - 0.05 12.3 0.1 0.71 8.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_14 PF13173.1 GAO81239.1 - 0.055 13.3 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.10 GAO81239.1 - 0.058 12.0 0.1 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 GAO81239.1 - 0.1 12.0 1.3 0.8 9.1 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 GAO81239.1 - 0.12 11.8 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 GAO81239.1 - 0.12 11.8 1.7 11 5.5 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 GAO81239.1 - 0.14 11.6 0.1 8.3 5.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 GAO81239.1 - 0.26 10.2 0.3 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_28 PF13521.1 GAO81239.1 - 0.39 10.6 1.6 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAO81239.1 - 1.3 7.9 0.3 20 4.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain TPR_12 PF13424.1 GAO81241.1 - 5.6e-83 272.9 37.5 3.1e-13 49.4 0.0 6.5 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.1 GAO81241.1 - 5.6e-62 204.0 21.9 6.1e-09 35.5 0.0 10.1 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 GAO81241.1 - 1.9e-13 49.8 8.7 0.015 14.9 0.8 6.4 3 1 4 7 7 7 5 TPR repeat TPR_16 PF13432.1 GAO81241.1 - 9e-12 45.3 21.3 0.0078 16.8 0.0 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAO81241.1 - 2.6e-11 42.3 12.9 0.17 11.7 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO81241.1 - 5e-10 39.1 24.4 0.42 11.3 0.0 8.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO81241.1 - 4.8e-09 35.4 16.5 0.056 13.3 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAO81241.1 - 5.1e-07 29.0 6.5 7.1 6.4 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAO81241.1 - 1.2e-06 28.2 1.8 0.57 10.5 0.0 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO81241.1 - 1.1e-05 25.3 20.8 2.8 8.6 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO81241.1 - 0.0017 18.6 10.6 0.16 12.2 0.0 6.0 4 2 5 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAO81241.1 - 1.3 9.6 20.7 1.7 9.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAO81242.1 - 1.6e-69 234.6 24.0 1.9e-69 234.3 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81242.1 - 2.7e-16 59.2 26.8 1.6e-15 56.7 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 GAO81242.1 - 0.0049 15.4 0.0 0.007 14.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 GAO81243.1 - 2.4e-82 276.9 27.5 2.9e-82 276.6 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81243.1 - 1.6e-29 102.7 21.6 2.6e-29 102.0 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81243.1 - 1.7e-10 39.7 9.2 6.3e-09 34.5 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Tmemb_170 PF10190.4 GAO81243.1 - 7.4 6.6 8.8 0.31 11.1 0.1 2.9 3 0 0 3 3 3 0 Putative transmembrane protein 170 Glyco_hydro_43 PF04616.9 GAO81245.1 - 4.8e-43 147.2 8.0 5.4e-43 147.1 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FhuF PF06276.7 GAO81246.1 - 9.8e-23 80.8 0.0 1.9e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.7 GAO81246.1 - 1.5e-17 63.6 0.2 4.6e-17 62.1 0.1 1.8 1 1 0 1 1 1 1 IucA / IucC family p450 PF00067.17 GAO81247.1 - 2.9e-59 200.8 0.0 3.7e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 GAO81249.1 - 2.1e-76 257.2 0.0 3e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Cys_Met_Meta_PP PF01053.15 GAO81249.1 - 1.3e-34 119.1 0.0 1.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phe_hydrox_dim PF07976.7 GAO81249.1 - 4.2e-27 94.8 0.0 8.7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 GAO81249.1 - 2.1e-05 23.5 0.0 3.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAO81249.1 - 0.00015 20.3 0.0 0.00025 19.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAO81249.1 - 0.00057 19.8 0.0 0.0075 16.1 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO81249.1 - 0.00082 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Aminotran_1_2 PF00155.16 GAO81249.1 - 0.00097 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DAO PF01266.19 GAO81249.1 - 0.0013 17.6 0.5 0.015 14.1 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO81249.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 GAO81249.1 - 0.0037 16.1 0.1 0.0058 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 GAO81249.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.22 GAO81249.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO81249.1 - 0.08 12.9 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAO81249.1 - 0.23 11.0 0.0 0.56 9.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_3 PF01596.12 GAO81250.1 - 3.6e-32 111.0 0.0 4.2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAO81250.1 - 3.5e-13 50.2 0.0 5.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81250.1 - 2.4e-06 28.1 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81250.1 - 6.5e-06 25.8 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO81250.1 - 4.7e-05 23.0 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAO81250.1 - 0.00049 20.1 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAO81250.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 GAO81250.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CP_ATPgrasp_2 PF14403.1 GAO81251.1 - 0.005 15.5 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 ATP-grasp_4 PF13535.1 GAO81251.1 - 0.054 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain TTL PF03133.10 GAO81251.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Host_attach PF10116.4 GAO81251.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells Zn_clus PF00172.13 GAO81253.1 - 0.0031 17.3 0.2 0.0081 16.0 0.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 GAO81254.1 - 6.9e-46 156.5 2.5 8.5e-46 156.2 1.7 1.0 1 0 0 1 1 1 1 RTA1 like protein TctB PF07331.6 GAO81254.1 - 0.94 9.1 8.2 1 9.0 0.3 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family HET PF06985.6 GAO81255.1 - 5.9e-27 94.5 1.4 1.7e-22 80.0 0.2 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 GAO81255.1 - 9.6e-16 57.9 0.0 1.3e-12 47.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81255.1 - 2.2e-12 46.1 0.0 0.00059 19.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAO81255.1 - 8.8e-11 41.6 0.3 7.3e-08 32.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO81255.1 - 2.5e-10 40.6 0.0 8.7e-07 29.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81255.1 - 1.3e-05 24.9 0.0 0.056 13.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Fungal_trans PF04082.13 GAO81256.1 - 2.3e-19 69.2 0.4 3.9e-19 68.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FA_desaturase PF00487.19 GAO81257.1 - 9.9e-14 51.3 19.5 9.9e-14 51.3 13.5 2.2 1 1 1 2 2 2 1 Fatty acid desaturase HTH_23 PF13384.1 GAO81257.1 - 0.043 13.4 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain M-factor PF03855.8 GAO81257.1 - 0.2 11.6 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 M-factor Glyco_hydro_6 PF01341.12 GAO81258.1 - 3.8e-117 390.9 1.4 5e-117 390.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 GAO81258.1 - 5.4e-13 48.3 10.4 2.9e-12 46.0 7.2 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Acyl-CoA_dh_1 PF00441.19 GAO81260.1 - 1.2e-31 109.8 3.9 2.1e-31 109.0 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO81260.1 - 1.1e-20 72.9 0.7 2.1e-20 71.9 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAO81260.1 - 2.7e-14 53.6 1.7 2.4e-13 50.6 0.0 3.0 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAO81260.1 - 4e-09 36.8 3.6 6.1e-09 36.2 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PBP PF01161.15 GAO81261.1 - 2.2e-21 76.2 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.11 GAO81262.1 - 9.1e-50 169.3 20.5 9.1e-50 169.3 14.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81262.1 - 1.7e-12 46.6 24.9 5.5e-12 44.9 17.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAO81262.1 - 2.9e-06 25.7 4.4 5.6e-06 24.8 3.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 GAO81262.1 - 0.0039 16.6 1.3 0.0039 16.6 0.9 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) Corona_S2 PF01601.11 GAO81262.1 - 2.6 6.0 5.6 0.56 8.2 1.3 1.6 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein ADH_N PF08240.7 GAO81263.1 - 5.6e-30 103.3 0.4 9.8e-30 102.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81263.1 - 6.5e-19 67.7 0.0 9.7e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 GAO81264.1 - 2.6e-06 27.2 8.3 4.3e-06 26.5 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO81264.1 - 2.2e-05 23.4 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4632 PF15451.1 GAO81264.1 - 0.097 12.6 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Zn_clus PF00172.13 GAO81265.1 - 3e-06 27.0 9.1 3e-06 27.0 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAO81266.1 - 1.1e-53 182.4 0.0 1.3e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 GAO81267.1 - 5e-06 26.1 1.0 1.6e-05 24.4 0.7 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81267.1 - 0.00036 20.1 0.5 0.00036 20.1 0.3 2.2 2 0 0 2 2 2 1 F-box domain Glyco_hydro_76 PF03663.9 GAO81268.1 - 5.3e-142 473.5 25.5 6.7e-142 473.2 17.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 GAO81270.1 - 2.8e-43 148.0 26.9 2.8e-43 148.0 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81270.1 - 7.2e-10 38.0 5.6 7.2e-10 38.0 3.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO81270.1 - 2e-08 32.9 3.3 2e-08 32.9 2.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.21 GAO81271.1 - 1.2e-09 37.9 11.7 5.7e-06 26.3 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO81271.1 - 2.8e-08 33.5 11.1 0.0011 19.1 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO81271.1 - 1.3e-07 31.5 4.5 1.3e-07 31.5 3.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain DUF2759 PF10958.3 GAO81271.1 - 0.15 11.6 0.7 0.26 10.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) zf-C2H2_6 PF13912.1 GAO81271.1 - 0.21 11.5 6.6 0.88 9.5 2.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 GAO81271.1 - 1.2 8.8 4.9 0.29 10.8 0.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_1 PF07690.11 GAO81272.1 - 1.7e-35 122.4 31.0 2e-35 122.1 21.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 GAO81273.1 - 3.4e-14 53.2 1.1 4.2e-14 52.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81273.1 - 1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO81273.1 - 1.4e-08 34.2 2.2 1.4e-05 24.3 0.6 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 GAO81273.1 - 4.4e-06 26.1 0.1 7.1e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 GAO81273.1 - 4.9e-05 21.9 1.0 9.6e-05 21.0 0.7 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAO81273.1 - 0.00021 21.0 0.0 0.00055 19.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAO81273.1 - 0.00047 19.6 0.0 0.00064 19.2 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 GAO81273.1 - 0.013 14.1 0.1 0.02 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 GAO81273.1 - 0.031 13.8 2.4 0.13 11.8 1.7 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 GAO81273.1 - 0.046 12.9 1.7 0.067 12.4 1.2 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Thiolase_C PF02803.13 GAO81273.1 - 0.13 11.6 0.9 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Thiolase, C-terminal domain Glyco_hydro_3 PF00933.16 GAO81274.1 - 1.4e-62 211.3 0.0 2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO81274.1 - 1.6e-45 155.4 0.1 2.8e-45 154.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO81274.1 - 1.9e-07 30.9 0.0 6.2e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain adh_short PF00106.20 GAO81275.1 - 6.5e-14 52.1 0.2 1.1e-13 51.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81275.1 - 6.5e-06 25.9 0.1 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81275.1 - 2.7e-05 24.0 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO81275.1 - 0.00038 19.9 0.0 0.00099 18.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81275.1 - 0.0024 17.9 0.1 0.0062 16.5 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF3425 PF11905.3 GAO81276.1 - 2.5e-21 76.0 0.0 4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1996 PF09362.5 GAO81277.1 - 8.6e-58 195.7 0.1 1.1e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4066 PF13278.1 GAO81278.1 - 2.3e-24 85.5 0.0 3.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO81278.1 - 3.7e-07 29.6 0.0 5.4e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 DJ-1/PfpI family HET PF06985.6 GAO81279.1 - 1.9e-21 76.6 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MBA1 PF07961.6 GAO81279.1 - 0.064 12.0 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 MBA1-like protein CVNH PF08881.5 GAO81281.1 - 9.1e-17 61.1 0.1 6.1e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 CVNH domain Trp_halogenase PF04820.9 GAO81282.1 - 6.6e-35 120.6 0.1 6.8e-19 67.8 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 GAO81282.1 - 1.6e-11 43.8 0.0 1e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO81282.1 - 2.4e-06 26.9 0.0 5.5e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO81282.1 - 2.7e-06 27.4 0.0 6.8e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO81282.1 - 3.2e-06 26.2 0.0 0.00013 21.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81282.1 - 2e-05 24.5 0.0 8.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAO81282.1 - 0.005 15.7 0.0 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 GAO81282.1 - 0.0053 15.8 0.0 0.079 12.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAO81282.1 - 0.0067 14.9 0.0 0.013 13.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO81282.1 - 0.023 13.5 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.17 GAO81283.1 - 8.1e-48 163.0 0.0 2.6e-42 144.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.21 GAO81284.1 - 3.9e-76 255.9 0.0 7.9e-76 254.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO81284.1 - 1.5e-54 185.4 0.0 2.8e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO81284.1 - 1.6e-31 108.6 1.1 2.9e-31 107.7 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO81284.1 - 3.4e-30 105.9 0.0 1.2e-29 104.1 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAO81284.1 - 5.9e-19 68.1 1.4 2.1e-10 40.7 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 GAO81284.1 - 1.1e-08 34.8 0.1 0.023 14.4 0.0 3.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81284.1 - 1.4e-08 34.9 2.6 2.6e-06 27.5 0.0 3.9 4 0 0 4 4 4 1 Alpha/beta hydrolase family Zn_clus PF00172.13 GAO81284.1 - 7.4e-06 25.7 12.5 7.4e-06 25.7 8.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.18 GAO81284.1 - 0.0011 18.0 0.1 0.0027 16.7 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 GAO81284.1 - 0.013 15.0 0.2 0.072 12.6 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.3 GAO81284.1 - 0.016 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 GAO81285.1 - 1e-18 68.0 2.7 2e-18 67.1 1.6 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 GAO81285.1 - 4.9e-16 58.7 0.7 3e-15 56.1 0.5 1.9 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 GAO81285.1 - 7.2e-16 58.2 0.1 1.2e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO81285.1 - 4.9e-07 29.1 0.1 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 GAO81285.1 - 3.2e-05 23.7 0.0 9.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAO81285.1 - 3.7e-05 23.4 0.2 0.001 18.6 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAO81285.1 - 0.00019 20.8 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.8 GAO81285.1 - 0.025 14.0 0.0 0.15 11.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 GAO81285.1 - 0.039 13.3 0.0 0.86 8.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAO81285.1 - 0.057 12.9 0.8 0.17 11.4 0.5 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cupin_1 PF00190.17 GAO81286.1 - 1.5e-10 40.6 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 GAO81286.1 - 1.8e-05 24.1 0.0 6.9e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Cupin domain MscL PF01741.13 GAO81287.1 - 7e-15 55.3 0.5 1.2e-14 54.5 0.3 1.4 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Stc1 PF12898.2 GAO81287.1 - 0.015 15.2 1.0 0.023 14.7 0.7 1.2 1 0 0 1 1 1 0 Stc1 domain zf-BED PF02892.10 GAO81287.1 - 0.019 14.7 2.0 0.033 13.9 1.4 1.4 1 0 0 1 1 1 0 BED zinc finger C1_1 PF00130.17 GAO81287.1 - 0.026 14.2 1.9 0.043 13.5 1.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VIT1 PF01988.14 GAO81287.1 - 0.027 13.9 1.2 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 VIT family PyrI_C PF02748.10 GAO81287.1 - 0.68 9.4 3.6 0.27 10.7 0.6 1.7 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain MFS_1 PF07690.11 GAO81288.1 - 2.5e-34 118.5 54.5 2.5e-26 92.2 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81288.1 - 7.4e-06 24.8 40.6 0.013 14.1 8.9 3.6 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 GAO81288.1 - 0.0007 19.3 4.8 0.0007 19.3 3.4 3.2 3 0 0 3 3 3 1 MFS_1 like family Cupin_2 PF07883.6 GAO81290.1 - 5.9e-10 38.4 0.0 1.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CFEM PF05730.6 GAO81291.1 - 0.0028 17.4 3.8 0.0065 16.2 2.4 1.7 1 1 1 2 2 2 1 CFEM domain Vps54 PF07928.7 GAO81291.1 - 0.18 11.9 0.4 0.3 11.2 0.3 1.4 1 0 0 1 1 1 0 Vps54-like protein Ashwin PF15323.1 GAO81291.1 - 1.1 9.1 5.5 1.3 8.9 3.8 1.2 1 0 0 1 1 1 0 Developmental protein Acyl_transf_3 PF01757.17 GAO81293.1 - 4.3e-46 157.3 34.8 5e-46 157.0 24.1 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 GAO81294.1 - 1.4e-12 47.9 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pyridoxal_deC PF00282.14 GAO81295.1 - 3.3e-109 364.7 0.0 4e-109 364.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAO81295.1 - 0.029 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Epimerase PF01370.16 GAO81296.1 - 1.4e-17 63.9 0.0 3.9e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO81296.1 - 1.2e-15 57.0 0.0 2.4e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO81296.1 - 2.1e-14 53.9 0.3 9.8e-14 51.7 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO81296.1 - 4.4e-09 35.6 0.1 3.1e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAO81296.1 - 1.3e-08 34.4 0.2 1.8e-07 30.6 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAO81296.1 - 4.2e-05 23.5 1.4 0.00012 22.0 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAO81296.1 - 0.00058 18.8 0.1 0.00094 18.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO81296.1 - 0.00079 18.4 0.1 0.056 12.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 GAO81296.1 - 0.0013 18.4 1.0 0.0044 16.6 0.7 1.8 1 1 0 1 1 1 1 KR domain Ribonuc_L-PSP PF01042.16 GAO81297.1 - 6.2e-10 38.8 0.1 8e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4336 PF14234.1 GAO81298.1 - 1.5e-17 63.7 0.0 2.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) PBP_like_2 PF12849.2 GAO81299.1 - 2.1e-12 47.1 5.6 2.8e-12 46.6 3.9 1.1 1 0 0 1 1 1 1 PBP superfamily domain Catalase PF00199.14 GAO81300.1 - 6.5e-160 532.0 0.6 8.8e-160 531.5 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAO81300.1 - 8.7e-19 67.1 0.1 1.7e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Glyco_hydro_65m PF03632.10 GAO81301.1 - 2.5e-91 306.1 0.3 1.4e-90 303.6 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 GAO81301.1 - 5.4e-54 183.1 0.2 1.4e-53 181.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 GAO81301.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Pro_dh PF01619.13 GAO81302.1 - 8.6e-39 133.3 0.0 2.2e-38 131.9 0.0 1.6 2 0 0 2 2 2 1 Proline dehydrogenase F420_oxidored PF03807.12 GAO81302.1 - 5.2e-17 62.0 0.1 2.6e-16 59.8 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.1 GAO81302.1 - 1.2e-07 31.7 0.7 7.4e-07 29.1 0.1 2.6 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation AAA_assoc PF14363.1 GAO81302.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA ApbA PF02558.11 GAO81302.1 - 0.034 13.5 0.1 0.11 11.8 0.0 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 GAO81302.1 - 0.034 14.6 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IMS_C PF11799.3 GAO81302.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Kin17_mid PF10357.4 GAO81303.1 - 5.8e-51 171.4 3.9 5.8e-51 171.4 2.7 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 GAO81303.1 - 0.0001 22.3 1.5 0.00022 21.2 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO81303.1 - 0.0017 18.4 3.7 0.0022 18.1 1.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAO81303.1 - 0.027 14.5 0.9 0.027 14.5 0.6 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SNAPc_SNAP43 PF09808.4 GAO81303.1 - 0.044 13.4 0.2 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ycf1 PF05758.7 GAO81303.1 - 0.17 9.5 6.6 0.27 8.8 4.6 1.3 1 0 0 1 1 1 0 Ycf1 Menin PF05053.8 GAO81303.1 - 0.24 9.5 3.5 0.28 9.3 2.4 1.2 1 0 0 1 1 1 0 Menin Actin PF00022.14 GAO81304.1 - 8.6e-24 83.6 0.0 1.2e-21 76.6 0.0 2.8 2 1 0 2 2 2 2 Actin CBFD_NFYB_HMF PF00808.18 GAO81305.1 - 2.6e-17 62.6 0.2 2.6e-17 62.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO81305.1 - 4.7e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 GAO81305.1 - 0.0078 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mrr_N PF14338.1 GAO81305.1 - 0.11 12.5 0.8 0.18 11.8 0.2 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain YolD PF08863.5 GAO81305.1 - 0.99 9.2 3.9 2 8.3 2.7 1.5 1 0 0 1 1 1 0 YolD-like protein adh_short PF00106.20 GAO81306.1 - 2.2e-29 102.4 0.1 3.5e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81306.1 - 4.2e-10 39.5 0.2 1.4e-09 37.8 0.2 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81306.1 - 5.8e-10 39.3 0.0 6.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO81306.1 - 2.8e-05 24.2 0.1 4.9e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO81306.1 - 6.4e-05 22.4 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAO81306.1 - 0.0019 18.1 0.1 0.0042 17.0 0.0 1.5 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 GAO81306.1 - 0.0061 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 GAO81306.1 - 0.0087 15.3 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAO81306.1 - 0.047 12.3 0.0 0.16 10.6 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAO81306.1 - 0.071 11.9 0.0 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAO81306.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 GAO81306.1 - 0.11 12.2 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 GAO81307.1 - 4.1e-28 98.3 0.0 5.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase zf-CCCH PF00642.19 GAO81307.1 - 1.3e-07 31.0 13.6 9.7e-07 28.3 1.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pyr_redox PF00070.22 GAO81307.1 - 0.003 17.9 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RRM_5 PF13893.1 GAO81307.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO81307.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4197 PF13852.1 GAO81307.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) NAD_binding_8 PF13450.1 GAO81307.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ldh_1_N PF00056.18 GAO81307.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SMC_Nse1 PF07574.8 GAO81308.1 - 4.8e-41 140.6 0.0 6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 GAO81308.1 - 2.9e-12 46.3 8.1 4.7e-12 45.6 5.6 1.4 1 0 0 1 1 1 1 RING-like domain HTH_27 PF13463.1 GAO81308.1 - 0.00044 20.5 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain Mrr_N PF14338.1 GAO81308.1 - 0.0028 17.7 0.1 0.032 14.3 0.0 2.3 2 0 0 2 2 2 1 Mrr N-terminal domain zf-RING_2 PF13639.1 GAO81308.1 - 0.023 14.5 6.3 0.038 13.8 4.3 1.4 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.17 GAO81308.1 - 0.027 14.2 1.9 0.027 14.2 1.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PaaX PF07848.7 GAO81308.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 PaaX-like protein RQC PF09382.5 GAO81308.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 RQC domain DUF2161 PF09929.4 GAO81308.1 - 0.086 12.7 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) DUF4095 PF13338.1 GAO81308.1 - 0.12 12.4 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) zf-P11 PF03854.9 GAO81308.1 - 0.2 11.1 1.3 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4 PF00097.20 GAO81308.1 - 0.42 10.2 4.1 0.87 9.3 2.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_31 PF13847.1 GAO81309.1 - 4e-30 104.4 0.0 5.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81309.1 - 1.1e-18 67.5 0.0 3.3e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO81309.1 - 7.7e-16 57.9 0.0 1.3e-15 57.1 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAO81309.1 - 1.7e-14 53.9 0.0 5.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81309.1 - 1.3e-12 48.2 0.0 2.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO81309.1 - 3.8e-11 43.0 0.0 6.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81309.1 - 1.5e-10 41.0 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO81309.1 - 3.8e-10 39.3 0.1 6.9e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAO81309.1 - 1.4e-09 37.8 0.1 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 GAO81309.1 - 3e-08 34.0 0.0 5.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAO81309.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAO81309.1 - 2.7e-05 23.6 0.0 3.9e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 GAO81309.1 - 0.00088 18.3 0.0 0.0019 17.2 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 GAO81309.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase UPF0020 PF01170.13 GAO81309.1 - 0.0047 16.5 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 GAO81309.1 - 0.0077 15.5 0.1 0.016 14.5 0.1 1.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_16 PF10294.4 GAO81309.1 - 0.012 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 GAO81309.1 - 0.031 13.2 0.1 2 7.3 0.0 2.1 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 GAO81309.1 - 0.041 12.9 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF739 PF05339.6 GAO81309.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) GCD14 PF08704.5 GAO81309.1 - 0.1 12.0 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.14 GAO81309.1 - 0.12 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 GAO81309.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Mid2 PF04478.7 GAO81310.1 - 0.0026 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor GST_N PF02798.15 GAO81311.1 - 9.3e-13 48.1 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO81311.1 - 2.8e-11 43.4 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO81311.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO81311.1 - 7.5e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO81311.1 - 2e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO81311.1 - 0.0085 16.5 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4066 PF13278.1 GAO81312.1 - 8.2e-22 77.2 0.0 1.8e-21 76.1 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO81312.1 - 2.5e-14 52.9 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Zn_clus PF00172.13 GAO81313.1 - 0.00069 19.4 6.7 0.0013 18.6 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAO81316.1 - 2e-33 115.5 35.3 2e-33 115.5 24.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81316.1 - 6e-07 28.0 19.7 6e-07 28.0 13.7 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF161 PF02588.10 GAO81316.1 - 5.1 7.4 11.8 9.5 6.6 5.5 3.4 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 CpeS PF09367.5 GAO81317.1 - 0.041 13.7 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 CpeS-like protein Beta-lactamase PF00144.19 GAO81318.1 - 8.4e-45 153.2 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Integrin_b_cyt PF08725.6 GAO81318.1 - 0.024 14.0 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Peptidase_S11 PF00768.15 GAO81318.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Abhydrolase_3 PF07859.8 GAO81319.1 - 2.3e-18 66.5 0.0 3.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81319.1 - 1.4e-07 31.3 0.0 2.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81319.1 - 4.2e-06 26.8 0.3 6.5e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO81319.1 - 7.4e-06 25.0 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 GAO81319.1 - 1.1e-05 24.7 0.0 0.0062 15.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 GAO81319.1 - 2.5e-05 23.2 0.0 0.00011 21.1 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 GAO81319.1 - 2.8e-05 23.6 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAO81319.1 - 0.0013 18.3 0.0 0.1 12.1 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAO81319.1 - 0.0075 15.0 0.1 0.014 14.1 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 GAO81319.1 - 0.08 11.4 0.0 0.3 9.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 GAO81320.1 - 1.4e-10 40.5 0.4 1.4e-10 40.5 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3425 PF11905.3 GAO81321.1 - 3.7e-20 72.2 0.2 1e-19 70.8 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO81321.1 - 0.015 15.2 8.8 0.025 14.5 6.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor MGDG_synth PF06925.6 GAO81321.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase NmrA PF05368.8 GAO81322.1 - 4.5e-28 98.0 0.0 1.2e-23 83.5 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 GAO81322.1 - 5.4e-10 39.5 0.1 7.5e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAO81322.1 - 0.00031 20.7 0.0 0.00084 19.3 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 GAO81322.1 - 0.00085 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAO81322.1 - 0.002 16.9 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO81322.1 - 0.0037 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO81322.1 - 0.0079 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 GAO81322.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 GAO81323.1 - 9.9e-25 87.3 0.5 5.1e-24 85.0 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81323.1 - 8.7e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81323.1 - 1.6e-08 34.3 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAO81323.1 - 4.1e-08 33.2 0.0 9.8e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO81323.1 - 3.4e-06 27.1 0.1 1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO81323.1 - 4.2e-05 22.7 0.1 6.1e-05 22.1 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Glyco_tran_WecB PF03808.8 GAO81323.1 - 0.029 13.7 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family F420_oxidored PF03807.12 GAO81323.1 - 0.031 14.6 0.0 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MgsA_C PF12002.3 GAO81324.1 - 3.6e-33 114.6 0.0 7.1e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAO81324.1 - 9.5e-14 51.7 0.0 2.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO81324.1 - 1.8e-12 46.8 0.0 5e-11 42.1 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAO81324.1 - 3.2e-08 33.3 0.0 1.1e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 GAO81324.1 - 0.001 18.9 0.0 1.6 8.5 0.0 2.6 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAO81324.1 - 0.0013 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAO81324.1 - 0.0015 18.6 0.0 0.007 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAO81324.1 - 0.0017 17.9 0.0 0.0043 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.13 GAO81324.1 - 0.0022 16.8 1.0 0.0052 15.6 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_14 PF13173.1 GAO81324.1 - 0.0024 17.7 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO81324.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO81324.1 - 0.0032 17.4 0.0 0.033 14.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 GAO81324.1 - 0.0033 16.9 0.0 0.36 10.2 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAO81324.1 - 0.0042 16.2 0.0 0.01 15.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 GAO81324.1 - 0.0061 16.0 0.1 1.5 8.1 0.0 2.6 1 1 1 2 2 2 1 AAA-like domain AAA_17 PF13207.1 GAO81324.1 - 0.0067 17.2 0.1 0.031 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 GAO81324.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase AAA_2 PF07724.9 GAO81324.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 GAO81324.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 GAO81324.1 - 0.031 13.0 0.0 0.075 11.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus Zeta_toxin PF06414.7 GAO81324.1 - 0.031 13.3 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 GAO81324.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 GAO81324.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAO81324.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAO81324.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 GAO81324.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 GAO81324.1 - 0.089 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.11 GAO81325.1 - 2.6e-26 92.1 45.9 2.6e-26 92.1 31.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 GAO81326.1 - 3.2e-13 49.3 0.2 1.1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81326.1 - 2.1e-07 30.6 0.2 5.5e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO81326.1 - 0.00024 22.0 0.0 0.00048 21.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EthD PF07110.6 GAO81327.1 - 2.6e-10 41.1 0.7 3.6e-10 40.6 0.5 1.2 1 0 0 1 1 1 1 EthD domain Abhydrolase_5 PF12695.2 GAO81328.1 - 2.6e-13 49.9 0.0 4.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81328.1 - 1.8e-12 47.6 2.3 1.8e-12 47.6 1.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAO81328.1 - 1.2e-08 33.9 0.0 1.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAO81328.1 - 9.2e-05 21.7 0.1 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 GAO81328.1 - 0.0076 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase MFS_1 PF07690.11 GAO81329.1 - 9.6e-45 152.8 47.6 3.2e-44 151.1 33.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81329.1 - 2e-17 62.6 21.8 2.5e-17 62.3 15.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO81329.1 - 2.7e-12 46.0 12.1 2.7e-12 46.0 8.4 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter AMP-binding PF00501.23 GAO81330.1 - 2e-83 280.1 0.0 5.2e-83 278.7 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAO81330.1 - 8.4e-74 248.2 0.0 1.6e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAO81330.1 - 4.3e-54 182.9 0.1 1.2e-52 178.2 0.0 3.1 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 GAO81330.1 - 1.1e-49 168.9 0.0 1.9e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 GAO81330.1 - 2e-47 161.2 0.1 3.1e-44 150.8 0.0 3.7 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 GAO81330.1 - 1.2e-44 152.7 0.5 4.1e-43 147.6 0.0 2.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAO81330.1 - 1.6e-44 152.5 0.2 7.5e-44 150.3 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 GAO81330.1 - 1.3e-38 132.3 0.0 1.6e-37 128.8 0.0 2.7 3 0 0 3 3 3 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAO81330.1 - 2e-28 98.5 0.0 5.9e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 GAO81330.1 - 1.6e-18 67.0 0.0 4e-16 59.1 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO81330.1 - 1.5e-16 60.4 0.2 1.2e-10 41.4 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO81330.1 - 3.4e-11 43.2 0.0 1.7e-10 41.0 0.0 2.4 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 GAO81330.1 - 2e-07 29.9 0.0 5.5e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 GAO81330.1 - 9e-06 24.8 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 GAO81330.1 - 0.016 14.1 0.0 9.4 5.0 0.0 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Methyltransf_23 PF13489.1 GAO81330.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81330.1 - 0.071 13.6 0.0 0.35 11.3 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81330.1 - 0.64 9.5 0.0 2.5 7.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Glucan_synthase PF02364.10 GAO81330.1 - 8.3 4.1 0.0 13 3.4 0.0 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Zn_clus PF00172.13 GAO81331.1 - 4.5e-06 26.4 9.2 4.5e-06 26.4 6.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.19 GAO81332.1 - 0.0012 18.4 2.9 0.0012 18.4 2.0 2.8 3 0 0 3 3 3 1 Sodium/calcium exchanger protein DUF3792 PF12670.2 GAO81332.1 - 0.0072 16.1 3.1 0.0072 16.1 2.2 3.5 4 1 0 4 4 4 1 Protein of unknown function (DUF3792) Strep_67kDa_ant PF06100.6 GAO81334.1 - 2.6e-114 382.3 0.0 3.3e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 GAO81334.1 - 0.00011 22.1 0.1 0.00027 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AIF-MLS PF14962.1 GAO81334.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Ldh_1_N PF00056.18 GAO81336.1 - 2e-25 89.2 0.2 3.1e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAO81336.1 - 1.3e-18 67.3 0.0 2.3e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 GAO81336.1 - 0.0042 16.8 0.2 0.0084 15.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family Malic_M PF03949.10 GAO81336.1 - 0.0055 16.2 0.1 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Glyco_hydro_4 PF02056.11 GAO81336.1 - 0.011 15.0 0.0 0.15 11.3 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.9 GAO81336.1 - 0.027 13.8 0.6 0.078 12.3 0.4 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 GAO81336.1 - 0.13 12.6 1.2 0.62 10.5 0.8 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PPDK_N PF01326.14 GAO81337.1 - 5.8e-92 308.2 0.1 1.2e-91 307.2 0.1 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 GAO81337.1 - 5.5e-58 196.1 0.0 8.9e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 GAO81337.1 - 1.1e-24 85.8 0.7 2.5e-24 84.6 0.2 1.9 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain LRR_4 PF12799.2 GAO81338.1 - 0.0025 17.3 1.1 11 5.7 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAO81338.1 - 0.09 12.8 2.8 4.6 7.6 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.2 GAO81338.1 - 0.12 12.0 0.0 0.43 10.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 GAO81338.1 - 0.2 11.3 2.0 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.1 GAO81338.1 - 0.27 11.3 1.5 5.4 7.3 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 GAO81338.1 - 1.3 9.5 7.7 4.4 7.9 0.0 5.3 8 0 0 8 8 8 0 Leucine rich repeat Zn_clus PF00172.13 GAO81339.1 - 2.2e-07 30.6 9.5 2.2e-07 30.6 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 GAO81340.1 - 8.8e-28 97.3 0.0 1.8e-25 89.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.1 GAO81340.1 - 1.2e-12 48.0 0.0 2.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81340.1 - 1.2e-08 35.3 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81340.1 - 2.5e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81340.1 - 4.9e-07 30.3 0.1 9.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81340.1 - 9.9e-07 29.1 0.0 1.7e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81340.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain COesterase PF00135.23 GAO81340.1 - 0.019 13.7 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family CheR PF01739.13 GAO81340.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 GAO81340.1 - 0.065 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 GAO81341.1 - 1.5e-36 125.8 49.9 2.7e-36 125.0 34.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81341.1 - 2.4e-12 45.8 15.5 2.4e-12 45.8 10.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO81341.1 - 2.4e-09 36.2 17.1 2.4e-09 36.2 11.9 3.6 2 2 2 4 4 4 2 Sugar (and other) transporter DHBP_synthase PF00926.14 GAO81342.1 - 1.6e-59 200.3 0.0 1.1e-58 197.6 0.0 2.0 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase adh_short_C2 PF13561.1 GAO81343.1 - 2.1e-24 86.6 0.0 2.5e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81343.1 - 1.9e-12 47.4 0.1 3.9e-12 46.4 0.1 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO81343.1 - 3e-06 27.0 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO81343.1 - 0.0062 16.5 0.3 0.02 14.8 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding RTA1 PF04479.8 GAO81344.1 - 6.5e-36 123.9 3.0 9.5e-36 123.3 2.1 1.2 1 0 0 1 1 1 1 RTA1 like protein CopD PF05425.8 GAO81344.1 - 4.8 7.4 7.3 4.1 7.6 0.6 2.4 2 0 0 2 2 2 0 Copper resistance protein D Fungal_trans PF04082.13 GAO81345.1 - 1.8e-10 40.1 2.4 3.1e-10 39.3 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81345.1 - 8.8e-07 28.7 6.1 2.5e-06 27.2 4.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_75 PF07335.6 GAO81346.1 - 9.1e-48 162.0 0.2 1.2e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Cellulase PF00150.13 GAO81348.1 - 1.8e-16 60.2 5.0 2.4e-16 59.7 3.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAO81348.1 - 4.6e-13 48.5 11.3 1.4e-12 47.0 7.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 GAO81348.1 - 0.00019 20.4 0.3 0.00034 19.6 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 GAO81348.1 - 0.00023 21.5 0.0 0.00047 20.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 GAO81348.1 - 0.00046 19.4 0.1 0.0019 17.3 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 GAO81348.1 - 0.011 14.7 1.3 0.17 10.8 0.1 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 10 ABC_tran PF00005.22 GAO81349.1 - 9.2e-11 42.1 0.9 1.2e-10 41.8 0.1 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 GAO81349.1 - 0.01 15.8 0.1 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 GAO81349.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.1 GAO81349.1 - 0.053 13.8 0.4 0.37 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAO81349.1 - 0.12 11.8 0.1 0.33 10.3 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO81349.1 - 0.12 12.2 0.4 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAO81349.1 - 0.13 11.3 0.1 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAO81349.1 - 0.14 12.9 0.1 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAO81349.1 - 0.33 11.2 0.2 0.33 11.2 0.2 2.0 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 GAO81349.1 - 0.41 7.9 4.6 0.094 10.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAO81349.1 - 0.69 8.3 2.9 0.29 9.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain Fungal_trans_2 PF11951.3 GAO81350.1 - 2.5e-12 46.1 1.8 3.4e-12 45.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81350.1 - 4.5e-07 29.6 6.7 7.4e-07 28.9 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CcmD PF04995.9 GAO81351.1 - 0.019 14.6 0.7 0.061 13.0 0.5 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SieB PF14163.1 GAO81351.1 - 5.9 6.4 5.8 0.84 9.2 0.5 2.1 3 0 0 3 3 3 0 Superinfection exclusion protein B p450 PF00067.17 GAO81352.1 - 6.4e-28 97.4 0.0 8.8e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 GAO81353.1 - 1.2e-49 167.4 15.3 1.1e-15 58.0 0.1 5.6 3 2 3 6 6 6 6 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAO81353.1 - 3.5e-34 117.1 2.6 2.9e-14 52.9 0.0 6.2 5 1 1 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 GAO81353.1 - 1.9e-30 104.0 11.5 4.7e-10 38.8 0.0 7.2 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 GAO81353.1 - 6.8e-07 28.7 3.6 0.85 8.7 0.0 5.1 5 1 1 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 GAO81353.1 - 3.2e-05 23.3 0.0 0.14 11.3 0.0 3.4 3 1 0 3 3 3 2 A-macroglobulin complement component p450 PF00067.17 GAO81354.1 - 2.3e-43 148.3 0.0 3.1e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAO81356.1 - 0.58 10.1 16.5 1.1 9.1 11.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 GAO81357.1 - 3.6e-10 39.5 0.0 1.3e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81357.1 - 1.3e-09 37.6 0.2 2.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 GAO81357.1 - 0.04 13.3 0.0 0.084 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81357.1 - 0.046 13.7 0.3 0.095 12.6 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 GAO81357.1 - 0.076 12.9 0.5 0.5 10.2 0.1 2.1 1 1 1 2 2 2 0 short chain dehydrogenase Nucleoplasmin PF03066.10 GAO81358.1 - 0.95 8.9 5.8 0.44 10.0 0.7 2.1 2 0 0 2 2 2 0 Nucleoplasmin MFS_1 PF07690.11 GAO81359.1 - 5.6e-41 140.4 48.8 1.4e-40 139.1 33.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81359.1 - 8.3e-10 37.8 14.5 8.3e-10 37.8 10.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.20 GAO81360.1 - 1.1e-25 90.5 0.1 1.6e-25 89.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81360.1 - 1.4e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81360.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAO81360.1 - 0.029 13.2 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 GAO81361.1 - 4e-23 81.4 0.8 9.2e-23 80.2 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO81361.1 - 0.0027 17.6 0.5 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like Glyco_hydro_3_C PF01915.17 GAO81362.1 - 4.6e-32 111.3 0.6 1.6e-30 106.3 0.4 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain zf-3CxxC PF13695.1 GAO81363.1 - 0.31 11.3 4.2 5.6 7.2 0.6 2.8 2 0 0 2 2 2 0 Zinc-binding domain Methyltransf_33 PF10017.4 GAO81364.1 - 0.085 12.7 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.11 GAO81365.1 - 1.3e-32 112.8 62.5 4.5e-24 84.8 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO81365.1 - 0.0008 19.1 0.0 0.0052 16.5 0.0 2.5 1 1 0 1 1 1 1 MFS_1 like family Abhydrolase_6 PF12697.2 GAO81366.1 - 1.6e-35 123.0 1.6 1.9e-35 122.8 1.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81366.1 - 2.7e-15 56.5 0.0 9.4e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81366.1 - 3.2e-14 52.9 0.1 4.4e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO81366.1 - 0.00026 20.7 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAO81366.1 - 0.02 13.3 0.0 0.033 12.6 0.0 1.3 1 1 0 1 1 1 0 Ndr family MFS_1 PF07690.11 GAO81367.1 - 1.7e-28 99.3 40.7 1.9e-27 95.9 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO81367.1 - 2.9e-06 25.7 2.1 2.9e-06 25.7 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MIP PF00230.15 GAO81368.1 - 8.9e-43 146.3 7.1 1.3e-42 145.8 4.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1212 PF06738.7 GAO81368.1 - 4.2 6.7 5.4 1 8.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) DUF2953 PF11167.3 GAO81368.1 - 6.7 6.7 6.5 2 8.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Acetyltransf_2 PF00797.12 GAO81369.1 - 8.4e-31 107.3 0.0 2.4e-30 105.8 0.0 1.7 1 1 0 1 1 1 1 N-acetyltransferase SUKH-4 PF14435.1 GAO81373.1 - 3.8e-09 36.5 0.0 5.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 SUKH-4 immunity protein F-box-like PF12937.2 GAO81373.1 - 0.00099 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81373.1 - 0.0067 16.0 0.1 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain TFIIA PF03153.8 GAO81374.1 - 0.0016 18.4 3.8 0.0017 18.3 2.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ABC2_membrane_3 PF12698.2 GAO81374.1 - 0.0017 17.4 3.5 0.0024 16.9 2.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Lin-8 PF03353.10 GAO81374.1 - 1.7 7.8 5.2 2.4 7.3 3.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.8 GAO81374.1 - 4.2 6.4 7.6 7.1 5.7 5.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rifin_STEVOR PF02009.11 GAO81374.1 - 6.9 6.2 10.0 13 5.2 7.0 1.5 1 0 0 1 1 1 0 Rifin/stevor family Ank_2 PF12796.2 GAO81375.1 - 5.6e-139 452.8 16.6 1.8e-20 73.0 0.1 8.8 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81375.1 - 1.1e-117 378.4 17.4 8.6e-10 37.9 0.1 18.2 18 0 0 18 18 18 18 Ankyrin repeat Ank_4 PF13637.1 GAO81375.1 - 1.1e-94 309.2 9.3 3.5e-11 43.3 0.0 14.9 3 2 12 15 15 15 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81375.1 - 5e-92 299.8 44.6 5.2e-10 39.2 0.0 12.3 3 2 12 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81375.1 - 1.5e-83 266.2 3.9 1.1e-05 25.1 0.0 18.1 18 0 0 18 18 18 17 Ankyrin repeat Shigella_OspC PF06128.6 GAO81375.1 - 3.2e-06 26.8 0.1 0.16 11.4 0.0 5.5 4 1 2 6 6 6 1 Shigella flexneri OspC protein DUF937 PF06078.6 GAO81375.1 - 1.2 9.3 9.9 1.9 8.7 0.5 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF937) ADH_N PF08240.7 GAO81376.1 - 3.3e-08 33.2 0.0 1.5e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81376.1 - 3.8e-08 32.9 1.9 1.9e-07 30.6 1.3 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 GAO81377.1 - 2.2e-32 112.1 33.4 2.2e-32 112.1 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 GAO81378.1 - 3.4e-20 71.9 0.0 4.1e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 GAO81379.1 - 3.5e-16 58.8 0.6 6.1e-16 58.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 GAO81380.1 - 1.4e-91 307.0 0.0 1.6e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PRAI PF00697.17 GAO81380.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase BTB PF00651.26 GAO81381.1 - 3.9e-13 49.3 0.9 9.1e-13 48.1 0.6 1.6 1 1 0 1 1 1 1 BTB/POZ domain SLT PF01464.15 GAO81382.1 - 3.1e-11 42.8 0.4 7.5e-11 41.5 0.3 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 GAO81382.1 - 0.0052 16.2 0.1 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Lysozyme-like adh_short PF00106.20 GAO81384.1 - 4.4e-24 85.2 1.1 5.9e-24 84.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81384.1 - 1.6e-13 50.9 0.1 2.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81384.1 - 3.5e-08 33.3 0.5 5e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO81384.1 - 0.00019 21.4 0.6 0.00045 20.2 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAO81384.1 - 0.00044 19.4 0.0 0.00055 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 GAO81384.1 - 0.0066 15.3 0.3 0.02 13.7 0.1 1.9 1 1 1 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAO81384.1 - 0.011 14.6 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAO81384.1 - 0.047 13.4 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF383 PF04063.9 GAO81384.1 - 0.048 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Epimerase PF01370.16 GAO81384.1 - 0.19 11.1 0.9 0.29 10.5 0.6 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_A4 PF01828.12 GAO81386.1 - 1e-91 305.6 10.4 1.3e-91 305.3 7.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family SKG6 PF08693.5 GAO81387.1 - 0.0001 21.5 0.1 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PolyA_pol PF01743.15 GAO81388.1 - 6.8e-23 81.2 0.1 4.5e-22 78.6 0.1 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAO81388.1 - 7.9e-09 34.9 0.0 1.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 GAO81388.1 - 0.041 13.6 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Ferric_reduct PF01794.14 GAO81389.1 - 9.5e-16 58.0 12.9 9.5e-16 58.0 8.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO81389.1 - 1.8e-14 53.9 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO81389.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 GAO81389.1 - 0.0089 16.1 0.0 0.05 13.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAO81389.1 - 0.03 14.8 0.0 5.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Senescence PF06911.7 GAO81390.1 - 0.00058 19.6 4.2 0.00078 19.1 2.9 1.2 1 0 0 1 1 1 1 Senescence-associated protein PBP PF01161.15 GAO81391.1 - 2.3e-21 76.1 0.0 2.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PHO4 PF01384.15 GAO81392.1 - 7.8e-117 389.5 14.8 9.8e-117 389.2 10.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 GAO81392.1 - 4.5 6.7 7.2 2.9 7.3 1.4 2.6 1 1 1 2 2 2 0 PgaD-like protein HLH PF00010.21 GAO81393.1 - 7.5e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 GAO81393.1 - 0.00099 19.3 2.1 0.038 14.2 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF904) Enterotoxin_b PF01376.13 GAO81393.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain PGM_PMM_I PF02878.11 GAO81394.1 - 3.9e-19 68.5 0.0 7.9e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 GAO81394.1 - 2.4e-08 33.8 0.1 8.4e-08 32.1 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 GAO81394.1 - 3.4e-08 33.5 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAO81394.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Dioxygenase_C PF00775.16 GAO81395.1 - 2.5e-44 150.7 0.0 3.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAO81395.1 - 7.3e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Ribonucleas_3_3 PF14622.1 GAO81396.1 - 1.2e-11 44.6 0.1 1.7e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAO81396.1 - 4.5e-11 43.2 0.0 1.3e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain DUF1408 PF07193.6 GAO81397.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Surf_Ag_VNR PF07244.10 GAO81399.1 - 0.049 14.0 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 Surface antigen variable number repeat EF-hand_7 PF13499.1 GAO81400.1 - 2.1e-07 30.9 0.2 3.1e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO81400.1 - 7.8e-06 24.8 0.6 0.045 13.0 0.0 2.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 GAO81400.1 - 1.6e-05 24.9 0.3 3e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.1 GAO81400.1 - 3.7e-05 23.2 0.4 0.035 13.9 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 GAO81400.1 - 0.0014 17.8 1.0 0.0046 16.2 0.0 2.3 3 1 0 3 3 3 1 EF hand Kinase-like PF14531.1 GAO81400.1 - 0.019 13.9 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 Kinase-like CDI PF02234.14 GAO81400.1 - 0.8 9.5 3.2 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Cellulase PF00150.13 GAO81401.1 - 6.1e-23 81.4 0.4 1.5e-22 80.1 0.3 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAO81401.1 - 4.1e-05 22.8 0.1 0.0001 21.6 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 GAO81401.1 - 0.00023 20.6 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Ceramidase PF05875.7 GAO81402.1 - 9.4e-78 260.9 7.1 1.1e-77 260.6 4.9 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 GAO81402.1 - 0.035 13.7 1.0 0.095 12.4 0.7 1.7 1 0 0 1 1 1 0 Trp-operon Leader Peptide RhodobacterPufX PF11511.3 GAO81404.1 - 0.58 9.6 0.0 0.58 9.6 0.0 2.7 3 0 0 3 3 3 0 Intrinsic membrane protein PufX MFS_1 PF07690.11 GAO81405.1 - 1.7e-27 96.0 54.1 1.7e-16 59.9 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.1 GAO81405.1 - 1.1 9.2 6.6 0.51 10.3 1.6 2.7 2 1 0 2 2 2 0 YrhC-like protein Fungal_trans PF04082.13 GAO81406.1 - 0.0026 16.6 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2165 PF09933.4 GAO81406.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) p450 PF00067.17 GAO81407.1 - 5e-40 137.4 0.0 9e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAO81407.1 - 1.5e-08 33.8 1.7 2.8e-08 32.9 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 GAO81410.1 - 1.2e-89 294.8 1.5 6.5e-20 71.2 0.0 7.7 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81410.1 - 3.3e-71 231.7 12.3 6.1e-07 28.9 0.0 13.4 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.1 GAO81410.1 - 2.8e-53 172.5 9.6 0.00056 19.9 0.0 13.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 GAO81410.1 - 3.4e-53 177.1 9.3 1.2e-08 35.2 0.1 10.9 5 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81410.1 - 1.1e-47 158.9 15.2 1.9e-07 31.0 0.0 11.5 7 2 6 13 13 13 11 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAO81410.1 - 1.6e-12 46.8 0.2 3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO81410.1 - 0.032 13.8 0.1 0.12 11.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain PDDEXK_4 PF14281.1 GAO81410.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily adh_short PF00106.20 GAO81411.1 - 1.5e-10 41.2 0.3 4.7e-10 39.6 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO81411.1 - 0.00015 21.4 0.1 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAO81411.1 - 0.00049 19.9 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Hydrolase_4 PF12146.3 GAO81411.1 - 0.04 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Polysacc_synt_2 PF02719.10 GAO81411.1 - 0.051 12.4 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Death PF00531.17 GAO81413.1 - 0.096 12.4 0.0 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Death domain GMC_oxred_N PF00732.14 GAO81414.1 - 1.2e-52 178.9 0.1 1.7e-52 178.4 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO81414.1 - 3.7e-34 118.0 0.4 6.2e-34 117.3 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAO81414.1 - 3.2e-05 23.0 1.2 0.012 14.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81414.1 - 4.4e-05 23.4 0.9 0.00018 21.4 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO81414.1 - 0.0016 17.3 0.4 0.032 13.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO81414.1 - 0.0023 17.8 0.2 0.0088 15.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO81414.1 - 0.0031 16.5 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAO81414.1 - 0.0061 15.6 0.3 0.014 14.4 0.2 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAO81414.1 - 0.0068 14.9 0.0 0.013 14.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 GAO81414.1 - 0.067 12.9 0.4 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAO81414.1 - 0.083 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 GAO81414.1 - 0.13 12.2 0.1 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Tautomerase_3 PF14832.1 GAO81416.1 - 7.9e-54 181.3 0.2 9.2e-54 181.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 GAO81416.1 - 0.0088 15.6 0.0 0.065 12.8 0.0 2.2 2 0 0 2 2 2 1 Tautomerase enzyme DUF1542 PF07564.6 GAO81416.1 - 0.02 14.8 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) bZIP_1 PF00170.16 GAO81417.1 - 0.00047 20.0 0.8 0.001 18.9 0.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Synaptonemal_3 PF15191.1 GAO81417.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Allexi_40kDa PF05549.6 GAO81417.1 - 0.12 11.6 1.4 0.22 10.8 1.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein MFS_1 PF07690.11 GAO81418.1 - 1.3e-26 93.1 54.7 5.6e-25 87.7 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81418.1 - 3.1e-07 29.3 41.3 3.1e-05 22.7 6.1 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAO81418.1 - 0.0029 17.3 2.2 0.0075 16.0 0.3 2.8 3 0 0 3 3 3 1 MFS_1 like family DUF1418 PF07214.7 GAO81418.1 - 0.049 13.2 0.6 0.049 13.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Aldedh PF00171.17 GAO81419.1 - 4.5e-149 496.7 0.0 5.7e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO81419.1 - 0.025 13.3 0.1 0.042 12.5 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1266 PF06889.6 GAO81419.1 - 0.031 14.0 0.1 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) S4 PF01479.20 GAO81419.1 - 0.1 12.0 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 S4 domain Isochorismatase PF00857.15 GAO81420.1 - 1.3e-19 70.7 0.4 2.1e-19 70.1 0.3 1.3 1 0 0 1 1 1 1 Isochorismatase family DUF2809 PF10990.3 GAO81420.1 - 0.057 13.8 0.1 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) FAD_binding_3 PF01494.14 GAO81421.1 - 5.5e-79 265.8 0.1 6.8e-79 265.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO81421.1 - 8.4e-06 24.9 0.0 4e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO81421.1 - 9.4e-05 22.7 0.0 0.0082 16.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO81421.1 - 0.00041 19.0 0.0 0.0015 17.2 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 GAO81421.1 - 0.00045 19.3 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAO81421.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO81421.1 - 0.00076 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO81421.1 - 0.0013 17.6 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAO81421.1 - 0.0041 15.6 0.0 0.0096 14.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 GAO81421.1 - 0.0056 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 GAO81421.1 - 0.0073 15.1 0.0 0.013 14.3 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 GAO81421.1 - 0.014 15.1 0.1 0.046 13.4 0.0 1.9 2 0 0 2 2 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAO81421.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAO81421.1 - 0.035 14.1 0.0 0.094 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAO81421.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.1 GAO81421.1 - 0.038 14.2 0.1 0.43 10.8 0.0 2.8 4 0 0 4 4 3 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 GAO81421.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 GAO81422.1 - 8.6e-11 41.7 1.1 2.6e-10 40.2 0.7 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO81422.1 - 2.9e-08 33.7 0.0 2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO81422.1 - 5.4e-06 26.5 0.1 0.00017 21.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO81422.1 - 5.4e-05 23.0 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO81422.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Glycolipid_bind PF06475.6 GAO81424.1 - 2.4e-60 202.7 0.0 2.8e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Putative glycolipid-binding CFEM PF05730.6 GAO81425.1 - 1.5e-06 27.9 3.3 2.7e-06 27.0 2.3 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 GAO81425.1 - 0.00036 19.7 0.5 0.00086 18.5 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 GAO81425.1 - 0.0064 15.1 0.3 0.0096 14.5 0.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein P12 PF12669.2 GAO81425.1 - 0.023 14.9 0.3 0.055 13.6 0.2 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family FAD_binding_4 PF01565.18 GAO81427.1 - 8.2e-21 73.9 0.3 1.4e-20 73.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain RTA1 PF04479.8 GAO81428.1 - 3.1e-53 180.5 10.0 3.1e-53 180.5 6.9 1.4 2 0 0 2 2 2 1 RTA1 like protein MFS_1 PF07690.11 GAO81430.1 - 2.6e-25 88.8 59.5 2.8e-20 72.3 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 GAO81431.1 - 2.1e-05 24.2 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81431.1 - 4.8e-05 22.9 0.0 0.00013 21.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_3 PF05899.7 GAO81431.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AMP-binding PF00501.23 GAO81432.1 - 3.3e-175 582.4 0.0 2.8e-99 332.3 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO81432.1 - 1.6e-47 161.8 0.3 1.1e-26 93.3 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO81432.1 - 1.9e-23 82.5 1.3 2.9e-11 43.4 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO81432.1 - 1.8e-13 51.2 0.1 1.5e-05 25.8 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain IucA_IucC PF04183.7 GAO81433.1 - 3.3e-24 85.5 2.1 5.2e-24 84.8 1.5 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 GAO81433.1 - 3.2e-15 56.4 0.4 1.1e-14 54.7 0.1 2.1 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter DUF1615 PF07759.7 GAO81433.1 - 0.17 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) DUF1924 PF09086.6 GAO81434.1 - 0.025 14.6 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1924) Mac PF12464.3 GAO81436.1 - 9.5e-17 60.7 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAO81436.1 - 3.6e-14 51.5 14.1 1.9e-12 46.0 3.8 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAO81436.1 - 5.6e-11 41.8 6.5 5.6e-11 41.8 4.5 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF1749 PF08538.5 GAO81437.1 - 6.8e-97 324.0 0.0 7.5e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAO81437.1 - 1.4e-07 31.6 0.6 1.9e-07 31.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81437.1 - 3.7e-05 23.5 0.0 7.9e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family XPA_C PF05181.7 GAO81437.1 - 0.069 12.7 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 XPA protein C-terminus Acetyltransf_8 PF13523.1 GAO81438.1 - 3.6e-37 127.5 1.0 6.1e-37 126.8 0.7 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 GAO81439.1 - 7e-50 169.4 0.0 8.7e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAO81439.1 - 1.7e-05 24.9 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 GAO81440.1 - 2.1e-87 293.2 0.0 1e-81 274.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO81440.1 - 8.3e-70 235.0 0.0 1.6e-37 128.9 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO81440.1 - 1.2e-26 92.7 0.1 2.4e-12 46.8 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO81440.1 - 1.1e-09 39.1 3.6 0.0025 18.7 0.1 3.9 2 1 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 GAO81440.1 - 0.33 9.4 0.0 9.8 4.5 0.0 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase ABC_membrane PF00664.18 GAO81441.1 - 7.8e-76 255.0 22.5 2.4e-46 158.3 1.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO81441.1 - 2.1e-64 215.8 0.0 2.5e-31 108.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAO81441.1 - 3.9e-15 55.7 2.3 0.00031 20.0 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO81441.1 - 3.4e-10 40.3 0.1 0.015 15.2 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAO81441.1 - 6.8e-09 35.1 0.6 0.0021 17.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO81441.1 - 1.1e-07 32.6 0.0 0.016 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO81441.1 - 3.1e-07 30.6 0.2 0.33 11.1 0.1 4.5 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 GAO81441.1 - 4.8e-07 29.8 0.3 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_16 PF13191.1 GAO81441.1 - 9.4e-07 28.9 4.6 0.0021 18.1 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 GAO81441.1 - 8.4e-06 25.0 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAO81441.1 - 1.1e-05 25.8 0.2 0.061 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO81441.1 - 1.9e-05 24.1 1.3 0.14 11.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 GAO81441.1 - 2.3e-05 24.0 0.3 0.37 10.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 GAO81441.1 - 0.00011 22.4 0.0 0.48 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 GAO81441.1 - 0.00015 21.4 0.1 0.1 12.2 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 GAO81441.1 - 0.00018 20.6 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 GAO81441.1 - 0.00032 20.5 0.0 1.2 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 GAO81441.1 - 0.00035 20.7 0.3 2.9 8.0 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 GAO81441.1 - 0.00037 19.1 0.5 0.0092 14.6 0.0 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 GAO81441.1 - 0.00063 19.2 1.4 0.27 10.6 0.1 3.0 4 0 0 4 4 2 2 AAA-like domain SbcCD_C PF13558.1 GAO81441.1 - 0.00078 19.3 0.2 2.2 8.2 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 GAO81441.1 - 0.0035 16.8 0.0 0.04 13.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.9 GAO81441.1 - 0.0035 17.0 0.0 2.9 7.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAO81441.1 - 0.0045 16.8 0.0 2.3 8.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 GAO81441.1 - 0.0046 16.8 0.1 1.5 8.8 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase MobB PF03205.9 GAO81441.1 - 0.049 13.3 0.2 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 GAO81441.1 - 0.068 11.7 0.0 6.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 GAO81441.1 - 0.11 11.2 0.0 4 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 GAO81441.1 - 0.15 10.8 0.2 13 4.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 GAO81441.1 - 0.21 10.6 0.0 1 8.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 GAO81442.1 - 2.7e-19 69.1 57.8 6.2e-19 67.9 34.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO81442.1 - 6e-08 31.3 23.9 2.4e-07 29.3 16.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 GAO81442.1 - 0.0025 17.7 4.4 0.023 14.6 0.7 3.5 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 DUF788 PF05620.6 GAO81442.1 - 0.019 14.8 7.5 0.072 12.9 5.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF788) UPF0233 PF06781.7 GAO81442.1 - 3.6 7.2 12.4 0.18 11.4 0.1 4.0 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0233) adh_short PF00106.20 GAO81443.1 - 5.1e-12 46.0 0.0 7.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81443.1 - 5.7e-06 26.1 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81443.1 - 0.0042 16.8 0.0 0.0086 15.8 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 GAO81443.1 - 0.045 12.7 0.0 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase TctA PF01970.11 GAO81443.1 - 0.063 11.6 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family HeLo PF14479.1 GAO81444.1 - 2.8e-25 89.3 0.2 9.5e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation adh_short PF00106.20 GAO81445.1 - 6.1e-20 71.7 0.5 1.3e-19 70.6 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81445.1 - 3.7e-08 33.4 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81445.1 - 6.3e-07 29.2 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81445.1 - 0.00012 21.6 0.3 0.00033 20.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81445.1 - 0.012 15.6 0.3 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding DXPR_C PF13288.1 GAO81445.1 - 0.14 12.1 0.2 0.66 10.0 0.0 2.0 1 1 1 2 2 2 0 DXP reductoisomerase C-terminal domain TPR_12 PF13424.1 GAO81446.1 - 1e-16 60.5 11.2 1.3e-07 31.4 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 GAO81446.1 - 1.1e-13 50.7 0.0 5.4e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_11 PF13414.1 GAO81446.1 - 0.00022 20.7 6.9 0.32 10.6 0.0 4.0 3 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAO81446.1 - 0.00027 20.6 11.6 2.9 8.0 0.4 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO81446.1 - 0.00043 20.8 3.6 4 8.2 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAO81446.1 - 0.00098 19.2 0.0 0.008 16.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain CorA PF01544.13 GAO81446.1 - 0.005 15.9 0.1 0.011 14.7 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_1 PF00515.23 GAO81446.1 - 0.044 13.4 3.5 8.3 6.1 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO81446.1 - 0.064 13.7 1.2 12 6.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO81446.1 - 0.12 12.3 11.3 4.3 7.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO81446.1 - 0.13 12.6 3.0 39 4.6 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 GAO81447.1 - 1.1e-13 51.8 0.0 1.7e-13 51.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO81447.1 - 3.7e-09 37.3 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO81447.1 - 1.7e-07 30.8 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like UPF0449 PF15136.1 GAO81448.1 - 0.13 12.4 0.2 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 RTBV_P46 PF06216.6 GAO81449.1 - 0.015 14.2 0.5 0.024 13.4 0.3 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF2277 PF10041.4 GAO81449.1 - 0.035 14.0 3.7 0.099 12.6 0.5 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) CENP-H PF05837.7 GAO81449.1 - 0.07 13.3 10.2 0.15 12.2 1.7 3.7 2 2 0 2 2 2 0 Centromere protein H (CENP-H) DUF2223 PF09985.4 GAO81449.1 - 0.11 11.7 0.0 0.49 9.6 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2223) Ded_cyto PF06920.8 GAO81449.1 - 0.19 10.9 3.3 1.4 8.2 0.2 2.8 2 1 1 3 3 3 0 Dedicator of cytokinesis FIVAR PF07554.8 GAO81449.1 - 0.33 11.2 2.6 88 3.4 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain DUF904 PF06005.7 GAO81449.1 - 0.61 10.4 9.5 0.89 9.8 1.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF904) YicC_N PF03755.8 GAO81449.1 - 0.74 9.7 8.0 0.6 10.0 1.8 2.7 2 1 1 3 3 3 0 YicC-like family, N-terminal region NPV_P10 PF05531.7 GAO81449.1 - 0.87 9.8 10.4 15 5.8 0.2 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TraF_2 PF13729.1 GAO81449.1 - 0.98 8.1 7.7 4.8 5.8 0.2 3.2 2 1 0 3 3 3 0 F plasmid transfer operon, TraF, protein AAA_13 PF13166.1 GAO81449.1 - 2.6 6.4 6.9 0.46 8.8 0.9 2.0 2 0 0 2 2 2 0 AAA domain FliJ PF02050.11 GAO81449.1 - 6.2 6.8 14.6 14 5.7 2.1 3.4 3 1 0 3 3 3 0 Flagellar FliJ protein NmrA PF05368.8 GAO81451.1 - 8.8e-24 84.0 0.0 1.4e-22 80.1 0.0 2.3 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 GAO81451.1 - 0.00024 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 GAO81451.1 - 0.00038 20.4 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO81451.1 - 0.0079 14.9 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO81451.1 - 0.0096 15.3 0.0 0.025 14.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 GAO81452.1 - 7.4e-18 64.3 4.0 1.8e-17 63.0 0.4 3.0 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81452.1 - 1.9e-17 63.0 1.5 4.1e-17 61.9 1.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81452.1 - 2.3e-10 41.4 0.1 2.3e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO81452.1 - 0.0039 16.3 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 GAO81453.1 - 3.3e-13 49.3 0.0 1.1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81453.1 - 6.8e-07 29.0 0.0 1.2e-05 24.9 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO81453.1 - 0.00015 22.6 0.0 0.00039 21.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase bZIP_1 PF00170.16 GAO81454.1 - 3.8e-05 23.5 4.3 7.3e-05 22.6 3.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor adh_short PF00106.20 GAO81455.1 - 2.3e-27 95.9 0.1 5.2e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81455.1 - 3.2e-21 76.1 0.1 4.3e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAO81455.1 - 3.8e-07 29.5 0.3 6.2e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81455.1 - 1.5e-06 28.3 0.1 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO81455.1 - 1.1e-05 25.1 0.1 1.9e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAO81455.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.21 GAO81455.1 - 0.00019 20.9 0.9 0.0029 17.1 0.2 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.16 GAO81455.1 - 0.0012 18.3 0.2 0.0036 16.7 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAO81455.1 - 0.0099 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 GAO81455.1 - 0.025 13.5 0.1 0.031 13.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase QRPTase_C PF01729.14 GAO81455.1 - 0.025 14.1 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain 3Beta_HSD PF01073.14 GAO81455.1 - 0.036 12.7 0.1 0.056 12.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 GAO81455.1 - 0.039 13.3 0.1 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAO81455.1 - 0.041 13.0 0.1 0.083 12.0 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAE PF03283.8 GAO81455.1 - 0.051 12.2 0.1 0.077 11.6 0.1 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Abhydrolase_6 PF12697.2 GAO81456.1 - 2.3e-23 83.2 0.0 2.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81456.1 - 6e-13 48.8 0.0 8.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81456.1 - 6e-08 32.5 0.3 1.1e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81456.1 - 4e-05 22.9 0.3 0.00021 20.6 0.1 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAO81456.1 - 0.013 15.1 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 GAO81456.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 GAO81456.1 - 0.032 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein ADH_zinc_N PF00107.21 GAO81457.1 - 1.1e-12 47.6 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81457.1 - 1.7e-05 24.5 0.0 5e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.19 GAO81458.1 - 7.2e-29 100.6 12.5 3e-15 55.7 4.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO81458.1 - 1.1e-09 37.4 12.2 5e-09 35.3 8.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ABM PF03992.11 GAO81459.1 - 0.038 14.0 2.3 0.17 11.9 0.3 2.5 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Serglycin PF04360.7 GAO81459.1 - 0.23 11.1 1.1 0.39 10.4 0.8 1.3 1 0 0 1 1 1 0 Serglycin NAD_binding_10 PF13460.1 GAO81460.1 - 1.6e-12 47.8 0.1 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO81460.1 - 2.4e-10 40.2 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO81460.1 - 9.4e-09 34.5 0.2 3.5e-06 26.1 0.1 2.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAO81460.1 - 6.1e-08 32.2 0.0 1.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAO81460.1 - 2.4e-07 29.7 0.1 0.00086 18.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO81460.1 - 1.6e-06 27.2 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Acylphosphatase PF00708.13 GAO81460.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Acylphosphatase adh_short PF00106.20 GAO81460.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Ank_2 PF12796.2 GAO81461.1 - 9.9e-18 64.2 2.7 9.4e-05 22.6 0.1 5.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81461.1 - 3.9e-17 62.2 4.7 0.0067 16.9 0.0 7.7 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81461.1 - 1.4e-11 44.2 8.0 0.16 12.2 0.1 6.5 6 1 0 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 GAO81461.1 - 1.2e-09 37.4 14.4 0.44 10.4 0.1 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 GAO81461.1 - 2.9e-09 36.2 6.1 1.3 9.4 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Transferase PF02458.10 GAO81462.1 - 3.3e-37 127.9 0.0 7.2e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Transferase family adh_short PF00106.20 GAO81463.1 - 4.9e-21 75.3 0.0 7.9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81463.1 - 3e-11 43.5 0.0 3.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81463.1 - 1.7e-06 27.8 0.1 5e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAO81463.1 - 0.0057 15.5 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAO81463.1 - 0.038 13.9 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Ank_2 PF12796.2 GAO81464.1 - 5.2e-61 202.9 0.0 7.7e-15 55.0 0.0 7.9 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81464.1 - 5e-36 122.4 4.7 1.8e-07 31.5 0.0 9.8 5 3 7 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81464.1 - 2.2e-32 110.3 2.1 8.4e-08 32.2 0.2 6.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 GAO81464.1 - 1e-31 107.1 0.0 0.0076 16.0 0.0 11.7 12 1 0 12 12 12 6 Ankyrin repeat Ank_3 PF13606.1 GAO81464.1 - 2e-27 92.5 0.0 0.016 15.3 0.0 11.7 13 0 0 13 13 13 6 Ankyrin repeat F-box-like PF12937.2 GAO81464.1 - 0.002 17.8 0.2 0.0046 16.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81464.1 - 0.044 13.4 0.1 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain Abhydrolase_3 PF07859.8 GAO81465.1 - 9.4e-35 120.1 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO81465.1 - 2.5e-09 36.6 0.0 5.2e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 GAO81465.1 - 1.5e-07 30.9 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 GAO81465.1 - 3.5e-05 23.6 0.0 5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 GAO81465.1 - 5e-05 23.2 1.8 8.4e-05 22.5 0.9 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO81465.1 - 0.00019 20.9 0.0 0.00036 20.0 0.0 1.5 2 0 0 2 2 2 1 Putative esterase AXE1 PF05448.7 GAO81465.1 - 0.0037 15.8 0.1 0.12 10.8 0.0 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 GAO81465.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAO81465.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 GAO81465.1 - 0.036 13.6 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Tannase PF07519.6 GAO81465.1 - 0.058 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Tannase and feruloyl esterase TrkH PF02386.11 GAO81466.1 - 5.3e-95 317.9 9.3 3.7e-93 311.9 1.5 2.2 2 0 0 2 2 2 2 Cation transport protein Metallophos PF00149.23 GAO81466.1 - 5.8e-13 48.6 0.2 1e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO81466.1 - 2.6e-05 24.1 0.0 7.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_12 PF01670.11 GAO81467.1 - 1.9e-12 47.2 4.2 1.4e-11 44.3 2.9 2.3 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 GAO81468.1 - 6e-39 134.1 0.0 8.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAO81468.1 - 4.6e-21 75.4 0.6 4.6e-21 75.4 0.4 3.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 GAO81468.1 - 1.8e-13 49.7 3.3 2.2e-08 32.8 1.3 2.9 1 1 2 3 3 3 2 Cellulose synthase Glycos_transf_2 PF00535.21 GAO81468.1 - 4e-13 49.3 0.0 6.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAO81468.1 - 5.7e-12 45.2 0.0 9.8e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 GAO81468.1 - 0.0059 15.0 0.0 0.075 11.4 0.0 2.3 2 1 0 2 2 2 1 Chitin synthase T2SF PF00482.18 GAO81468.1 - 0.4 10.6 2.9 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF465 PF04325.8 GAO81472.1 - 1.4 8.6 4.1 0.58 9.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) IBV_3B PF03622.8 GAO81473.1 - 0.053 13.5 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 IBV 3B protein Epimerase PF01370.16 GAO81474.1 - 4.1e-24 85.3 0.0 5.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO81474.1 - 9.2e-17 60.6 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO81474.1 - 3.2e-12 45.9 0.0 9.2e-12 44.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAO81474.1 - 2.7e-09 37.2 0.0 6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO81474.1 - 3.2e-06 27.1 0.0 1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81474.1 - 9.9e-06 25.3 0.0 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO81474.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAO81474.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family PrmA PF06325.8 GAO81474.1 - 0.068 12.2 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_6 PF12697.2 GAO81475.1 - 2.1e-26 93.2 0.1 6.6e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81475.1 - 2e-12 47.1 0.1 4.8e-12 45.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81475.1 - 1.1e-08 34.8 0.1 7.2e-08 32.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81475.1 - 7.3e-05 22.1 0.1 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 GAO81475.1 - 0.00051 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 GAO81475.1 - 0.0011 18.2 0.3 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAO81475.1 - 0.003 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 GAO81475.1 - 0.0039 16.6 0.2 0.023 14.1 0.1 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 GAO81475.1 - 0.005 16.3 0.2 0.026 13.9 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.8 GAO81475.1 - 0.006 16.1 0.3 0.085 12.4 0.1 2.1 2 0 0 2 2 2 1 PGAP1-like protein BAAT_C PF08840.6 GAO81475.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PRRSV_2b PF07069.6 GAO81475.1 - 0.033 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b DUF2048 PF09752.4 GAO81475.1 - 0.13 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF676 PF05057.9 GAO81475.1 - 0.17 11.1 0.2 0.38 9.9 0.1 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ribonuclease PF00545.15 GAO81476.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ribonuclease Plasmid_RAQPRD PF09686.5 GAO81476.1 - 0.00036 20.5 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 Plasmid protein of unknown function (Plasmid_RAQPRD) UAA PF08449.6 GAO81477.1 - 5.6e-14 51.7 17.9 7.5e-14 51.3 12.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAO81477.1 - 2.6e-10 40.1 6.0 2.6e-10 40.1 4.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family HSP70 PF00012.15 GAO81478.1 - 0.00062 17.8 0.0 0.0012 16.8 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO81478.1 - 0.12 10.8 0.0 0.64 8.5 0.0 2.0 3 0 0 3 3 3 0 MreB/Mbl protein Syndecan PF01034.15 GAO81479.1 - 0.019 14.6 0.1 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_YMGG PF13441.1 GAO81479.1 - 3.3 7.2 9.1 8.2 6.0 6.3 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper MFS_1 PF07690.11 GAO81480.1 - 9.3e-39 133.1 28.7 9.3e-39 133.1 19.9 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RasGEF_N PF00618.15 GAO81480.1 - 0.17 11.9 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif zf-H2C2_2 PF13465.1 GAO81481.1 - 1.6e-06 28.0 3.4 1.6e-06 28.0 2.3 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAO81481.1 - 5.2e-06 26.4 25.6 0.001 19.2 5.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO81481.1 - 0.012 15.8 23.4 0.064 13.6 5.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBR PF02207.15 GAO81481.1 - 0.14 11.8 4.0 0.31 10.8 2.8 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_jaz PF12171.3 GAO81481.1 - 1.6 8.9 3.9 23 5.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 GAO81481.1 - 9.3 6.1 10.4 9.4 6.0 0.2 2.5 1 1 1 2 2 2 0 BED zinc finger 3HCDH_N PF02737.13 GAO81482.1 - 1.8e-31 109.1 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAO81482.1 - 3.5e-11 43.3 0.0 7.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAO81482.1 - 3e-05 23.9 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAO81482.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 GAO81482.1 - 0.0058 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 GAO81482.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO81482.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAO81482.1 - 0.051 13.8 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Sortase PF04203.8 GAO81482.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Sortase family NAD_binding_8 PF13450.1 GAO81482.1 - 0.14 12.2 0.1 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_61 PF03443.9 GAO81483.1 - 3.1e-84 282.1 0.1 3.1e-84 282.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAO81483.1 - 1.1e-11 44.2 14.4 3.5e-11 42.5 10.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Zn_clus PF00172.13 GAO81485.1 - 3.1e-07 30.2 12.3 3.1e-07 30.2 8.6 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KTSC PF13619.1 GAO81485.1 - 0.0051 16.4 0.1 0.8 9.3 0.0 2.9 2 1 1 3 3 3 2 KTSC domain BTB PF00651.26 GAO81486.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3072 PF11272.3 GAO81486.1 - 0.0092 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3072) p450 PF00067.17 GAO81487.1 - 4.1e-41 140.9 0.0 7.4e-37 126.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HAD PF12710.2 GAO81488.1 - 3.1e-09 37.2 0.1 5.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAO81488.1 - 0.00026 20.2 0.0 0.002 17.3 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase Chitin_bind_3 PF03067.10 GAO81488.1 - 0.0077 16.5 0.1 0.034 14.4 0.1 1.9 1 1 0 1 1 1 1 Chitin binding domain NAD_binding_1 PF00175.16 GAO81490.1 - 1.7e-30 105.7 0.0 1.7e-29 102.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 GAO81490.1 - 2.1e-26 91.5 0.1 4.1e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 GAO81490.1 - 6.5e-26 90.3 0.0 1.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAO81490.1 - 1.6e-06 28.1 0.0 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAO81490.1 - 0.0007 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 GAO81491.1 - 4e-73 246.5 0.0 5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1359 PF07097.6 GAO81491.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) MFS_1 PF07690.11 GAO81493.1 - 3.8e-28 98.2 28.8 5.5e-14 51.6 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO81493.1 - 1.7e-07 30.0 21.7 0.0026 16.2 3.3 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 GAO81493.1 - 1.1e-06 27.5 17.9 1.9e-06 26.7 12.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 GAO81493.1 - 0.00047 18.3 7.0 0.052 11.6 0.1 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 GAO81493.1 - 0.011 15.4 16.1 0.044 13.5 0.1 5.0 5 1 1 6 6 6 0 MFS_1 like family MFS_1 PF07690.11 GAO81494.1 - 1e-31 109.9 23.5 1.5e-31 109.4 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily X8 PF07983.8 GAO81494.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 X8 domain Ceramidase PF05875.7 GAO81494.1 - 0.39 9.8 5.1 0.18 10.8 0.8 2.2 3 0 0 3 3 3 0 Ceramidase DALR_2 PF09190.6 GAO81495.1 - 0.091 13.0 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 DALR domain CoA_trans PF01144.18 GAO81496.1 - 5.3e-98 326.5 0.9 5.6e-57 192.4 0.0 3.0 3 0 0 3 3 3 2 Coenzyme A transferase Fungal_trans PF04082.13 GAO81496.1 - 2.6e-05 23.2 0.1 4.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AcetylCoA_hyd_C PF13336.1 GAO81496.1 - 0.00096 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain bZIP_2 PF07716.10 GAO81498.1 - 1.3e-11 44.0 17.1 1.3e-11 44.0 11.8 3.7 2 1 1 3 3 3 2 Basic region leucine zipper Snf7 PF03357.16 GAO81498.1 - 9.3e-06 25.1 8.7 9.3e-06 25.1 6.1 2.3 2 0 0 2 2 2 1 Snf7 bZIP_1 PF00170.16 GAO81498.1 - 6.9e-05 22.7 17.9 6.9e-05 22.7 12.4 3.2 3 1 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.12 GAO81498.1 - 0.0017 18.6 15.4 0.0017 18.6 10.7 2.6 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF4157 PF13699.1 GAO81498.1 - 0.56 10.3 4.1 1.5 9.0 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Bystin PF05291.6 GAO81499.1 - 1.6e-128 427.9 0.0 2.4e-128 427.3 0.0 1.2 1 0 0 1 1 1 1 Bystin Amidase PF01425.16 GAO81501.1 - 1.1e-105 354.0 0.3 1.4e-105 353.7 0.2 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 GAO81502.1 - 4.3e-11 42.4 0.0 1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81502.1 - 0.00038 20.1 0.0 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 GAO81502.1 - 0.0068 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase T2SL PF05134.8 GAO81502.1 - 0.034 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L Metallophos PF00149.23 GAO81503.1 - 6e-11 42.1 0.8 9.8e-11 41.4 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 GAO81504.1 - 3.1e-46 157.1 0.0 4.4e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAO81504.1 - 1.4e-35 121.9 0.1 5e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF1691 PF07950.6 GAO81505.1 - 1.2e-55 186.0 10.0 9.6e-39 131.7 3.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 GAO81505.1 - 9.9 6.0 14.1 7.2 6.4 0.2 2.5 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TRM PF02005.11 GAO81506.1 - 7.2e-109 364.1 0.0 1.2e-93 314.1 0.0 2.1 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 GAO81506.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 GAO81506.1 - 0.028 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF2067 PF09840.4 GAO81506.1 - 0.029 13.8 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Cut8_N PF14482.1 GAO81506.1 - 0.062 13.3 0.1 0.24 11.4 0.1 2.1 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Methyltransf_31 PF13847.1 GAO81506.1 - 0.085 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.21 GAO81507.1 - 1.7e-21 76.8 0.0 4.1e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 GAO81507.1 - 7.9e-21 74.9 0.0 2.6e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 GAO81507.1 - 9.3e-18 64.1 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 GAO81507.1 - 9.7e-11 41.5 0.0 2.5e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAO81507.1 - 1.3e-06 28.4 0.0 3.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81507.1 - 0.00087 18.9 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAO81508.1 - 2.1e-81 273.7 0.0 6e-80 268.9 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 GAO81508.1 - 1.9e-39 133.8 0.0 4.3e-39 132.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 GAO81508.1 - 3.3e-31 106.8 0.4 1.3e-30 104.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 GAO81508.1 - 6.2e-21 74.5 0.1 2.2e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAO81508.1 - 0.00036 19.7 0.2 0.0038 16.4 0.2 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase MCRS_N PF13325.1 GAO81508.1 - 0.24 10.8 0.1 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein TFIIF_alpha PF05793.7 GAO81509.1 - 2.7e-09 35.9 57.4 8.8e-07 27.6 0.9 3.4 1 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF676 PF05057.9 GAO81510.1 - 1e-42 145.9 0.0 7.5e-28 97.3 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAO81510.1 - 0.0037 17.0 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAO81510.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 GAO81510.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 GAO81510.1 - 0.053 12.6 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Inositol_P PF00459.20 GAO81511.1 - 9.3e-63 212.0 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family CAP_GLY PF01302.20 GAO81511.1 - 0.045 13.4 0.5 8.9 6.0 0.0 2.5 2 0 0 2 2 2 0 CAP-Gly domain DUF383 PF04063.9 GAO81512.1 - 1.2e-74 250.0 1.6 2.2e-74 249.1 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 GAO81512.1 - 2e-24 84.9 2.3 2.5e-24 84.5 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) H_kinase_N PF12282.3 GAO81512.1 - 0.069 12.7 0.3 0.18 11.4 0.2 1.7 1 0 0 1 1 1 0 Signal transduction histidine kinase His_Phos_2 PF00328.17 GAO81513.1 - 3.6e-119 398.1 0.4 4.8e-119 397.7 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DAGK_cat PF00781.19 GAO81513.1 - 4.2e-10 39.1 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RimK PF08443.6 GAO81513.1 - 8e-07 28.7 0.0 2.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 GAO81514.1 - 2.9e-65 219.7 0.6 1.2e-63 214.3 0.0 2.4 1 1 1 2 2 2 2 Utp21 specific WD40 associated putative domain WD40 PF00400.27 GAO81514.1 - 9.4e-21 72.8 34.5 3.2e-05 23.6 0.1 9.2 11 0 0 11 11 11 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAO81514.1 - 0.047 11.9 0.0 0.12 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain YccV-like PF08755.6 GAO81515.1 - 3.9e-26 90.8 0.0 7e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DEAD PF00270.24 GAO81517.1 - 2.4e-06 27.1 0.1 4e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAO81517.1 - 0.0061 16.4 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glutenin_hmw PF03157.8 GAO81518.1 - 5.3e-05 21.7 22.5 7.9e-05 21.1 15.6 1.2 1 0 0 1 1 1 1 High molecular weight glutenin subunit Collagen PF01391.13 GAO81518.1 - 0.066 12.7 13.7 0.032 13.7 7.8 1.7 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3505 PF12013.3 GAO81519.1 - 2.3e-15 56.7 0.5 2.3e-15 56.7 0.3 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF3505) Pyridoxal_deC PF00282.14 GAO81521.1 - 1.3e-17 63.3 0.0 5.1e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Cytomega_UL20A PF05984.7 GAO81522.1 - 0.056 13.6 0.2 0.059 13.5 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein HTH_6 PF01418.12 GAO81523.1 - 0.085 12.6 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Herpes_ORF11 PF04797.8 GAO81524.1 - 0.0043 15.5 0.1 0.01 14.2 0.1 1.6 1 1 0 1 1 1 1 Herpesvirus dUTPase protein DUF4232 PF14016.1 GAO81524.1 - 0.2 11.2 1.2 0.94 9.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) Chromo PF00385.19 GAO81525.1 - 2.2e-12 46.4 1.4 3.3e-12 45.8 1.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 GAO81525.1 - 0.03 14.0 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PWWP PF00855.12 GAO81525.1 - 0.045 13.9 0.2 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 PWWP domain ArsR PF09824.4 GAO81525.1 - 0.075 12.3 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 ArsR transcriptional regulator Arch_fla_DE PF04659.8 GAO81527.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal flagella protein DUF262 PF03235.9 GAO81528.1 - 0.0083 16.1 1.1 0.0083 16.1 0.7 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF262 PAS_10 PF13596.1 GAO81528.1 - 0.029 14.6 0.4 0.056 13.7 0.3 1.4 1 0 0 1 1 1 0 PAS domain Nucleo_P87 PF07267.6 GAO81528.1 - 0.03 13.0 3.9 0.024 13.3 0.7 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Allexi_40kDa PF05549.6 GAO81528.1 - 0.19 11.0 2.1 0.42 9.8 1.5 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Phage_GPO PF05929.6 GAO81528.1 - 0.33 10.1 3.7 0.52 9.5 2.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 GAO81528.1 - 2 7.9 9.6 3.9 7.0 6.6 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 GAO81528.1 - 5.9 7.1 14.6 11 6.2 10.1 1.3 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.14 GAO81530.1 - 7.2e-55 185.4 0.0 1.1e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAO81530.1 - 2e-12 46.7 0.1 9e-12 44.6 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAO81530.1 - 3e-10 39.4 0.1 9.5e-10 37.8 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 GAO81530.1 - 6.2e-07 29.2 2.5 1.6e-06 27.9 1.7 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) RicinB_lectin_2 PF14200.1 GAO81531.1 - 4.3e-07 30.2 0.2 1.8e-05 25.0 0.1 2.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Botulinum_HA-17 PF05588.6 GAO81531.1 - 0.0041 17.0 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Clostridium botulinum HA-17 protein G8 PF10162.4 GAO81531.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.5 1 1 0 1 1 1 0 G8 domain Tyrosinase PF00264.15 GAO81532.1 - 1.3e-51 175.8 3.4 3.1e-51 174.6 2.4 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M20 PF01546.23 GAO81533.1 - 3.5e-12 46.2 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO81533.1 - 0.00017 21.2 0.0 0.00048 19.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain DegQ PF08181.6 GAO81534.1 - 0.039 13.6 1.2 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 DegQ (SacQ) family Pyridox_ox_2 PF12900.2 GAO81535.1 - 2.1e-10 40.5 0.1 2.3e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase G_glu_transpept PF01019.16 GAO81536.1 - 1.5e-141 472.4 0.5 1.9e-141 472.0 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PSDC PF12588.3 GAO81537.1 - 2.4e-32 111.4 0.0 3.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 GAO81537.1 - 1.2e-23 83.4 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase GILT PF03227.11 GAO81537.1 - 3.2e-13 49.4 0.4 7.1e-13 48.3 0.1 1.7 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) RnfC_N PF13375.1 GAO81537.1 - 0.0033 17.1 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Peptidase_M20 PF01546.23 GAO81538.1 - 6.2e-30 104.1 0.0 1.1e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO81538.1 - 1.4e-12 47.3 0.0 3.6e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO81538.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 RcsC PF09456.5 GAO81538.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) PS_Dcarbxylase PF02666.10 GAO81539.1 - 1.2e-53 181.3 0.0 1.9e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3725 PF12523.3 GAO81539.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3725) ketoacyl-synt PF00109.21 GAO81540.1 - 2.5e-72 243.4 0.0 6.1e-72 242.1 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO81540.1 - 2.3e-51 175.0 0.1 5.4e-51 173.8 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO81540.1 - 4.2e-32 110.4 1.0 3.5e-31 107.5 0.3 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAO81540.1 - 7.8e-32 110.6 0.5 3.4e-31 108.5 0.1 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 GAO81540.1 - 2e-09 37.3 0.0 5.8e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAO81540.1 - 5.8e-08 32.8 0.1 1.5e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 GAO81540.1 - 9.8e-08 32.3 0.0 8.4e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.5 GAO81540.1 - 2e-05 24.3 0.1 2e-05 24.3 0.1 3.2 3 1 0 3 3 3 1 KR domain adh_short PF00106.20 GAO81540.1 - 0.00032 20.6 0.1 0.0032 17.4 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.1 GAO81540.1 - 0.00047 19.7 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO81540.1 - 0.00059 18.9 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 GAO81540.1 - 0.0014 19.0 0.0 0.0052 17.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAO81540.1 - 0.016 14.6 0.0 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 GAO81540.1 - 0.03 13.4 0.0 0.074 12.1 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FAE1_CUT1_RppA PF08392.7 GAO81540.1 - 0.13 11.3 0.1 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein p450 PF00067.17 GAO81541.1 - 1.6e-23 83.0 0.0 2.4e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO81542.1 - 1.2e-26 93.2 0.0 2.1e-26 92.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PSI_8 PF00796.13 GAO81542.1 - 0.18 11.3 0.6 0.38 10.3 0.4 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII adh_short PF00106.20 GAO81543.1 - 9.8e-25 87.3 3.4 1.6e-24 86.6 2.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81543.1 - 1.5e-17 64.1 0.1 2.1e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81543.1 - 3.5e-07 30.0 2.9 2.3e-06 27.4 2.0 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO81543.1 - 7.2e-05 22.5 1.6 0.00034 20.3 1.1 2.1 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAO81543.1 - 0.00033 20.7 0.4 0.0013 18.7 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO81543.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 GAO81543.1 - 0.019 14.5 0.3 0.051 13.1 0.2 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.10 GAO81543.1 - 0.045 13.3 0.5 0.065 12.8 0.3 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FtsJ PF01728.14 GAO81543.1 - 0.15 11.9 0.1 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase polyprenyl_synt PF00348.12 GAO81544.1 - 7.8e-54 182.2 0.0 9.2e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAO81544.1 - 0.0099 15.1 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain FAD_binding_3 PF01494.14 GAO81545.1 - 2.3e-21 76.2 0.1 6.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 GAO81545.1 - 0.011 14.5 0.0 0.79 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 GAO81545.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 GAO81546.1 - 3.8e-71 239.9 0.0 5e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO81547.1 - 2.6e-27 95.5 0.0 3.1e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 GAO81547.1 - 3.7e-27 95.7 0.0 5.8e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAO81547.1 - 0.12 10.8 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AMP-binding PF00501.23 GAO81548.1 - 3.1e-60 203.7 0.0 4.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_3 PF01494.14 GAO81549.1 - 6e-08 32.1 0.0 6.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_31 PF01055.21 GAO81550.1 - 1.5e-86 291.0 0.2 1.7e-86 290.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Alpha-amylase PF00128.19 GAO81551.1 - 9.3e-53 179.6 0.0 4.8e-29 101.7 0.0 2.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO81551.1 - 1.8e-33 114.4 0.4 6.7e-33 112.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 GAO81551.1 - 5.9e-31 105.9 0.0 1.1e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain DUF2235 PF09994.4 GAO81553.1 - 1.6e-96 322.8 0.0 2.1e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.11 GAO81554.1 - 1.6e-30 106.0 49.5 7.1e-30 103.8 34.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.6 GAO81554.1 - 0.0042 16.4 1.2 0.076 12.3 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1129) NADH_dh_m_C1 PF15088.1 GAO81554.1 - 0.098 12.1 1.4 0.3 10.5 0.5 2.2 1 1 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial ADH_N PF08240.7 GAO81555.1 - 6.4e-26 90.2 3.6 1.1e-25 89.4 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81555.1 - 1e-14 54.1 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81555.1 - 0.00012 23.0 0.0 0.0002 22.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO81555.1 - 0.0013 17.9 0.1 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAO81555.1 - 0.0019 17.8 0.2 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 GAO81555.1 - 0.027 14.0 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 GAO81556.1 - 3.1e-24 85.2 0.9 5e-24 84.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81556.1 - 1.1e-06 28.4 11.3 1.1e-06 28.4 7.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 GAO81556.1 - 0.0082 15.8 2.5 0.024 14.3 1.8 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat LssY_C PF14067.1 GAO81556.1 - 0.072 12.0 0.4 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 LssY C-terminus CASP_C PF08172.7 GAO81556.1 - 0.13 11.3 1.8 0.26 10.2 1.2 1.5 1 0 0 1 1 1 0 CASP C terminal TPR_10 PF13374.1 GAO81557.1 - 1.6e-52 173.9 48.1 1.7e-06 27.7 0.4 10.6 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.1 GAO81557.1 - 5.5e-46 154.3 39.2 1.4e-10 40.9 0.8 7.4 3 2 4 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 GAO81557.1 - 2.9e-24 82.9 30.2 0.042 13.6 0.1 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.1 GAO81557.1 - 1.1e-21 76.9 38.9 0.00014 22.1 0.6 8.9 1 1 8 9 9 9 8 Tetratricopeptide repeat Patatin PF01734.17 GAO81557.1 - 5.8e-21 75.3 0.1 2.1e-20 73.5 0.1 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_14 PF13428.1 GAO81557.1 - 8.6e-20 69.4 43.9 0.17 12.5 1.8 11.4 8 3 3 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAO81557.1 - 1.6e-18 65.2 20.1 0.77 10.1 0.1 10.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAO81557.1 - 1.2e-17 62.2 17.3 2.8 8.0 0.0 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAO81557.1 - 3.9e-17 62.4 38.6 0.0017 18.9 1.2 7.4 2 1 5 8 8 8 8 Tetratricopeptide repeat Apc3 PF12895.2 GAO81557.1 - 9.2e-17 60.9 30.7 0.0015 18.6 0.7 8.8 1 1 7 9 9 9 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 GAO81557.1 - 1.7e-16 60.1 50.4 0.15 12.1 0.4 10.8 1 1 9 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 GAO81557.1 - 6.3e-16 56.8 0.8 2 8.3 0.0 10.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO81557.1 - 4.6e-14 51.8 19.3 4.4 7.9 0.0 11.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO81557.1 - 4.1e-12 45.3 59.6 0.074 13.5 0.5 11.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAO81557.1 - 4.3e-10 39.0 27.7 0.16 11.6 0.2 6.6 1 1 9 10 10 10 10 TPR repeat NB-ARC PF00931.17 GAO81557.1 - 9.1e-10 37.8 0.0 1.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 GAO81557.1 - 7.1e-09 34.9 18.1 8.2 6.2 0.0 10.2 10 0 0 10 10 10 0 Tetratricopeptide repeat NACHT PF05729.7 GAO81557.1 - 8.6e-09 35.2 0.0 2.3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_3 PF07720.7 GAO81557.1 - 1.2e-08 34.5 51.4 0.18 11.6 0.4 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat ATP13 PF12921.2 GAO81557.1 - 1e-05 24.8 6.0 42 3.5 0.0 8.6 6 3 3 10 10 10 0 Mitochondrial ATPase expression AAA_22 PF13401.1 GAO81557.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain PPR PF01535.15 GAO81557.1 - 0.00014 21.6 0.0 62 3.8 0.0 7.7 10 0 0 10 10 10 0 PPR repeat AAA_31 PF13614.1 GAO81557.1 - 0.011 15.6 0.8 5.2 6.9 0.0 4.1 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAO81557.1 - 0.036 13.7 0.0 0.09 12.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 GAO81557.1 - 0.056 13.3 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C3HC PF07967.8 GAO81557.1 - 0.13 11.9 0.3 18 5.0 0.0 2.8 2 0 0 2 2 2 0 C3HC zinc finger-like Phage_Gp23 PF10669.4 GAO81557.1 - 0.28 11.2 9.4 8.5 6.5 0.0 6.1 5 3 4 9 9 8 0 Protein gp23 (Bacteriophage A118) AAA_10 PF12846.2 GAO81557.1 - 3.7 6.8 6.7 99 2.2 0.0 4.1 2 1 0 2 2 2 0 AAA-like domain F-box PF00646.28 GAO81558.1 - 0.0013 18.2 2.0 0.0044 16.6 0.2 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAO81558.1 - 0.0014 18.3 0.3 0.0032 17.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like AA_permease PF00324.16 GAO81559.1 - 6.1e-69 232.5 31.9 2.6e-68 230.5 22.1 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO81559.1 - 5.5e-23 81.1 31.3 1.1e-21 76.9 16.1 2.0 1 1 1 2 2 2 2 Amino acid permease DUF2207 PF09972.4 GAO81559.1 - 0.061 11.9 4.6 1.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 GAO81561.1 - 8.9e-22 77.2 26.4 8.9e-22 77.2 18.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81561.1 - 4.9e-08 31.9 32.1 3.6e-07 29.1 22.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter ATP-grasp_2 PF08442.5 GAO81563.1 - 6.8e-54 182.3 0.0 1.2e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HATPase_c PF02518.21 GAO81563.1 - 7.7e-21 73.8 0.0 1.9e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO81563.1 - 1.3e-18 67.0 0.0 5.1e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain Ligase_CoA PF00549.14 GAO81563.1 - 1.5e-18 66.8 0.4 3.6e-18 65.6 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase HisKA PF00512.20 GAO81563.1 - 6.1e-15 54.9 0.1 1.6e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ATP-grasp_5 PF13549.1 GAO81563.1 - 5.6e-11 42.0 0.0 9.8e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GAF_3 PF13492.1 GAO81563.1 - 0.00077 19.5 0.0 0.044 13.8 0.0 2.9 2 1 0 2 2 2 1 GAF domain ATP-grasp_4 PF13535.1 GAO81563.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain LysM PF01476.15 GAO81564.1 - 0.00034 20.4 0.6 0.00098 18.9 0.0 2.1 2 0 0 2 2 2 1 LysM domain SLT PF01464.15 GAO81564.1 - 0.075 12.5 0.1 0.21 11.0 0.1 1.8 1 1 0 1 1 1 0 Transglycosylase SLT domain DUF605 PF04652.11 GAO81564.1 - 1.9 7.7 13.5 2.9 7.1 9.4 1.2 1 0 0 1 1 1 0 Vta1 like NMO PF03060.10 GAO81565.1 - 2.8e-22 79.3 0.0 3.5e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 GAO81565.1 - 1.2e-07 30.8 0.7 3.2e-07 29.5 0.4 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAO81565.1 - 0.037 12.9 0.3 0.052 12.4 0.2 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase FA_hydroxylase PF04116.8 GAO81566.1 - 1.2e-14 54.6 15.2 1.2e-14 54.6 10.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SYF2 PF08231.7 GAO81568.1 - 0.09 12.8 3.5 0.097 12.7 2.4 1.0 1 0 0 1 1 1 0 SYF2 splicing factor YkyA PF10368.4 GAO81568.1 - 0.44 9.8 3.7 0.47 9.7 2.5 1.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4175 PF13779.1 GAO81568.1 - 0.53 7.9 6.1 0.48 8.0 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Amidase PF01425.16 GAO81570.1 - 1.5e-87 294.2 0.0 2e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 GAO81572.1 - 3.5e-15 55.5 0.1 3.6e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_2 PF00703.16 GAO81572.1 - 5e-14 52.6 0.6 1.9e-13 50.8 0.4 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAO81572.1 - 4.3e-09 36.1 0.0 8.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Cu-oxidase_3 PF07732.10 GAO81572.1 - 0.008 15.9 1.6 0.04 13.6 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_2_C PF02836.12 GAO81572.1 - 0.0098 14.8 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Methyltransf_11 PF08241.7 GAO81573.1 - 4.8e-19 68.6 0.0 7.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81573.1 - 7.6e-15 55.4 0.0 1.8e-14 54.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO81573.1 - 8.6e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81573.1 - 5.4e-14 52.4 0.0 8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81573.1 - 1.4e-13 50.8 0.0 1.8e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81573.1 - 5.7e-13 48.7 0.0 7.8e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO81573.1 - 5.8e-10 39.2 0.0 8.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO81573.1 - 5.9e-08 32.1 0.0 8.6e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAO81573.1 - 3.1e-07 29.9 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 GAO81573.1 - 4e-05 22.9 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 GAO81573.1 - 0.0029 16.6 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 GAO81573.1 - 0.022 14.0 0.0 0.87 8.8 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain N2227 PF07942.7 GAO81573.1 - 0.033 13.1 0.0 0.061 12.2 0.0 1.5 1 1 0 1 1 1 0 N2227-like protein Methyltransf_4 PF02390.12 GAO81573.1 - 0.035 13.1 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 GAO81573.1 - 0.054 13.1 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 GAO81573.1 - 0.072 12.3 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase T5orf172 PF10544.4 GAO81574.1 - 9.2e-15 54.8 0.0 2.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 GAO81574.1 - 1.9e-12 47.4 0.1 3.8e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF4658 PF15555.1 GAO81574.1 - 0.037 13.9 1.2 0.09 12.6 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Uso1_p115_C PF04871.8 GAO81575.1 - 4.3e-05 23.4 25.6 4.3e-05 23.4 17.8 3.4 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 GAO81575.1 - 0.002 17.6 30.4 0.05 13.0 6.3 2.6 1 1 0 2 2 2 2 Intermediate filament protein Tup_N PF08581.5 GAO81575.1 - 0.0048 17.0 11.8 0.015 15.4 0.0 4.2 1 1 2 4 4 4 1 Tup N-terminal BBP1_C PF15272.1 GAO81575.1 - 0.0088 15.6 0.9 0.0088 15.6 0.6 3.2 1 1 2 3 3 3 1 Spindle pole body component BBP1, C-terminal ADIP PF11559.3 GAO81575.1 - 0.041 13.7 33.1 0.81 9.5 8.2 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.6 GAO81575.1 - 0.047 13.4 4.7 0.7 9.6 0.1 2.6 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF4618 PF15397.1 GAO81575.1 - 0.12 11.7 22.8 0.27 10.5 5.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Tropomyosin PF00261.15 GAO81575.1 - 0.13 11.3 40.0 0.085 11.9 10.8 3.2 1 1 2 3 3 3 0 Tropomyosin CALCOCO1 PF07888.6 GAO81575.1 - 0.14 10.4 28.0 0.79 7.9 12.1 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.5 GAO81575.1 - 0.35 10.9 17.5 2.6 8.1 1.5 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 GAO81575.1 - 0.35 8.1 39.2 1.3 6.2 19.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 GAO81575.1 - 0.52 10.1 11.7 0.089 12.6 1.9 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 GAO81575.1 - 0.55 9.9 41.6 0.34 10.6 12.3 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 GAO81575.1 - 0.81 8.8 19.6 1.9 7.5 7.9 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 GAO81575.1 - 0.84 8.0 29.4 0.82 8.0 19.4 1.5 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 GAO81575.1 - 4.7 6.7 36.7 17 4.9 5.7 3.1 1 1 1 2 2 1 0 IncA protein DUF1664 PF07889.7 GAO81575.1 - 6.6 6.5 18.7 0.52 10.1 0.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) tRNA-synt_1 PF00133.17 GAO81576.1 - 1.4e-217 723.4 0.0 2.1e-217 722.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAO81576.1 - 1e-25 90.3 0.0 3.1e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAO81576.1 - 2.9e-18 65.7 0.1 6.7e-07 28.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAO81576.1 - 0.085 11.9 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Phage_NinH PF06322.6 GAO81576.1 - 0.15 11.7 0.1 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 Phage NinH protein Ank_2 PF12796.2 GAO81577.1 - 5.8e-17 61.8 0.0 2.5e-13 50.1 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81577.1 - 1.4e-15 57.3 2.1 1.5e-07 31.7 0.4 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 GAO81577.1 - 1.4e-15 56.1 1.7 9.3e-09 34.6 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAO81577.1 - 9.7e-12 44.7 2.2 1.7e-08 34.4 0.2 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81577.1 - 5.1e-11 41.6 3.0 4e-06 26.5 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat FAD_binding_4 PF01565.18 GAO81578.1 - 1.4e-20 73.2 1.1 2.4e-20 72.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO81578.1 - 9.4e-09 35.0 0.1 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 GAO81579.1 - 3.6e-16 59.5 0.8 5.6e-16 58.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81579.1 - 2.2e-06 27.4 0.2 3.3e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81579.1 - 4.1e-06 26.3 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81579.1 - 1.4e-05 25.1 0.2 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81579.1 - 0.046 12.9 0.1 0.1 11.8 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.1 GAO81579.1 - 0.049 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Tub_2 PF04525.7 GAO81580.1 - 3.3e-26 91.8 0.1 3.7e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 fn3 PF00041.16 GAO81581.1 - 5e-15 55.4 0.5 6e-10 39.1 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL PF00657.17 GAO81581.1 - 0.0016 18.3 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_6 PF12697.2 GAO81582.1 - 8.7e-13 48.6 0.1 1.3e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81582.1 - 9e-13 48.2 0.0 2.8e-12 46.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81582.1 - 2.6e-07 30.1 0.0 7.4e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.6 GAO81582.1 - 0.00071 18.2 0.0 0.0011 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 GAO81582.1 - 0.0021 17.5 0.2 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAO81582.1 - 0.0028 16.1 0.0 0.024 13.1 0.0 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAO81582.1 - 0.076 12.7 0.4 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.20 GAO81583.1 - 1.2e-14 54.5 0.0 2.4e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81583.1 - 0.037 13.6 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 KR domain SGL PF08450.7 GAO81584.1 - 0.00019 20.8 0.5 0.00029 20.2 0.4 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Methyltransf_2 PF00891.13 GAO81585.1 - 8.1e-14 51.3 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAO81585.1 - 0.0038 17.0 0.0 0.016 15.0 0.0 2.2 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.5 GAO81585.1 - 0.081 12.5 0.2 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain Sulfatase PF00884.18 GAO81585.1 - 0.11 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Sulfatase An_peroxidase PF03098.10 GAO81586.1 - 9.5e-81 271.7 0.0 3.2e-61 207.3 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 GAO81586.1 - 5.8e-05 21.7 0.0 0.00039 19.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 DUF676 PF05057.9 GAO81586.1 - 0.028 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAO81586.1 - 0.032 14.1 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO81586.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein CDO_I PF05995.7 GAO81587.1 - 2.8e-08 33.1 0.0 6.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 GAO81587.1 - 0.00076 18.8 0.0 0.0022 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Cupin_2 PF07883.6 GAO81587.1 - 0.0098 15.3 0.0 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Kelch_5 PF13854.1 GAO81588.1 - 4.3e-20 71.2 4.7 1e-17 63.6 0.7 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 GAO81588.1 - 5.8e-09 35.8 7.5 2e-06 27.8 0.2 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO81588.1 - 1.2e-05 25.2 1.8 0.0026 17.8 0.2 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 GAO81588.1 - 3.3e-05 23.3 3.1 0.0066 15.9 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 GAO81588.1 - 0.00014 21.5 5.3 0.0051 16.5 0.1 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Adeno_E3_CR2 PF02439.10 GAO81588.1 - 0.024 14.1 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 GAO81588.1 - 0.11 12.8 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.6 GAO81588.1 - 1.5 8.6 7.8 0.51 10.1 0.3 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) MFS_1 PF07690.11 GAO81590.1 - 8.4e-32 110.2 27.7 8.4e-32 110.2 19.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3017 PF11222.3 GAO81590.1 - 0.23 11.2 8.6 0.78 9.5 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) GFO_IDH_MocA PF01408.17 GAO81591.1 - 3.5e-18 66.2 0.0 6.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO81591.1 - 2.2e-15 56.4 0.2 5.3e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.11 GAO81592.1 - 5e-31 107.6 32.0 5e-31 107.6 22.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81592.1 - 1.3e-08 33.8 34.8 9.9e-08 30.9 24.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter GWT1 PF06423.7 GAO81592.1 - 2.8 8.0 8.9 7.6 6.6 3.8 2.9 2 1 0 2 2 2 0 GWT1 FecCD PF01032.13 GAO81593.1 - 0.022 13.6 4.9 0.028 13.2 1.7 2.1 2 0 0 2 2 2 0 FecCD transport family DUF773 PF05600.7 GAO81593.1 - 0.23 10.2 0.7 0.33 9.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) FAD_binding_3 PF01494.14 GAO81595.1 - 1.6e-24 86.6 0.1 5.5e-24 84.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO81595.1 - 2.6e-09 36.4 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81595.1 - 9.3e-05 22.3 0.3 0.00038 20.4 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO81595.1 - 0.00043 18.8 0.0 0.019 13.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAO81595.1 - 0.00076 19.8 0.0 0.1 13.0 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO81595.1 - 0.0058 15.5 0.3 0.053 12.3 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO81595.1 - 0.013 15.6 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAO81595.1 - 0.034 13.8 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAO81595.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 GAO81595.1 - 0.061 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO81595.1 - 0.072 12.8 0.2 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 GAO81595.1 - 0.086 12.2 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAO81595.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AOX PF01786.12 GAO81597.1 - 0.27 10.6 4.0 0.38 10.1 2.8 1.3 1 1 0 1 1 1 0 Alternative oxidase GMC_oxred_N PF00732.14 GAO81598.1 - 3.9e-63 213.3 0.0 4.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO81598.1 - 2.9e-37 128.1 0.0 5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO81598.1 - 5.6e-06 25.4 0.6 0.065 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO81598.1 - 9.1e-05 22.4 0.4 0.00045 20.1 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO81598.1 - 0.00089 18.2 2.1 0.033 13.1 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO81598.1 - 0.0013 17.7 0.5 0.002 17.1 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAO81598.1 - 0.0047 16.8 0.4 0.036 13.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO81598.1 - 0.022 14.8 0.1 7.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO81598.1 - 0.04 12.9 0.1 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 GAO81598.1 - 0.054 13.2 1.6 0.44 10.3 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAO81598.1 - 0.099 11.7 0.8 0.37 9.8 0.1 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 GAO81598.1 - 0.14 10.6 0.8 1.9 6.8 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Ribonuclease_3 PF00636.21 GAO81599.1 - 1.3e-28 99.6 0.1 4.5e-13 49.6 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 GAO81599.1 - 1.7e-21 75.8 0.0 4.5e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 GAO81599.1 - 1.3e-19 70.4 0.9 8.2e-07 29.0 0.0 3.8 2 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 GAO81599.1 - 1.5e-16 59.9 0.0 4e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2499 PF10693.4 GAO81599.1 - 0.026 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) dsrm PF00035.20 GAO81600.1 - 8.5e-05 23.0 0.1 0.00016 22.2 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Anillin PF08174.6 GAO81600.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 2 0 0 2 2 2 0 Cell division protein anillin OTT_1508_deam PF14441.1 GAO81601.1 - 1.7e-18 66.7 0.0 3.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Glyco_hydro_76 PF03663.9 GAO81602.1 - 3.5e-154 513.6 21.6 4.3e-154 513.3 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aminotran_1_2 PF00155.16 GAO81603.1 - 4.3e-48 164.1 0.0 5.3e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TauD PF02668.11 GAO81605.1 - 2.3e-30 106.1 0.1 2.9e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAO81605.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 CsiD ADH_N PF08240.7 GAO81606.1 - 4.1e-25 87.6 0.0 1e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81606.1 - 1.5e-19 69.8 2.9 2.2e-19 69.2 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81606.1 - 1.7e-06 28.9 0.6 2.9e-06 28.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 GAO81606.1 - 0.0058 16.3 0.4 0.67 9.7 0.0 3.3 2 1 2 4 4 4 1 HAD-hyrolase-like Tyrosinase PF00264.15 GAO81608.1 - 1.1e-50 172.8 0.1 2.1e-50 171.9 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase dCMP_cyt_deam_1 PF00383.17 GAO81609.1 - 6.3e-09 35.4 0.0 7.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAO81609.1 - 0.12 12.2 0.6 2.2 8.1 0.4 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase Ank_2 PF12796.2 GAO81610.1 - 4.4e-141 459.6 33.5 4.4e-21 75.0 0.1 9.2 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81610.1 - 3.4e-128 411.5 43.4 9.2e-10 37.8 0.0 18.3 19 1 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 GAO81610.1 - 1.6e-93 305.5 21.1 6.4e-16 58.4 0.1 12.9 4 4 9 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81610.1 - 1.5e-87 285.6 31.0 3.8e-11 42.8 0.3 14.1 4 3 9 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81610.1 - 8.4e-79 251.5 23.3 2e-06 27.4 0.0 17.9 18 1 0 18 18 18 16 Ankyrin repeat F-box-like PF12937.2 GAO81610.1 - 0.011 15.3 0.2 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 GAO81610.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF2384 PF09722.5 GAO81610.1 - 0.082 12.7 0.3 5.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) Shigella_OspC PF06128.6 GAO81610.1 - 0.15 11.4 0.0 88 2.4 0.0 4.1 4 0 0 4 4 4 0 Shigella flexneri OspC protein FAD_binding_2 PF00890.19 GAO81611.1 - 3.3e-80 269.9 1.3 3.9e-80 269.7 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO81611.1 - 3.9e-09 36.1 0.1 6.3e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAO81611.1 - 5.6e-09 35.3 0.1 2.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81611.1 - 1.2e-07 31.6 0.7 3e-07 30.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO81611.1 - 3.8e-07 28.9 0.1 5.3e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAO81611.1 - 3.4e-06 26.3 0.2 1.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 GAO81611.1 - 1.1e-05 25.3 0.2 0.00034 20.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO81611.1 - 4.2e-05 22.7 0.4 6.8e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO81611.1 - 0.0014 18.7 0.2 0.0034 17.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO81611.1 - 0.073 11.9 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 GAO81611.1 - 0.16 10.7 0.9 0.25 10.1 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transferase PF02458.10 GAO81612.1 - 8e-21 73.9 0.0 1.6e-08 33.4 0.0 3.1 3 0 0 3 3 3 3 Transferase family p450 PF00067.17 GAO81613.1 - 2.6e-69 233.9 0.0 3.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 GAO81614.1 - 7.4e-27 93.8 0.0 1.8e-20 72.8 0.0 2.5 2 1 0 2 2 2 2 Transferase family p450 PF00067.17 GAO81615.1 - 7.9e-64 215.8 0.0 1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAO81616.1 - 2.6e-25 89.2 0.7 3.6e-25 88.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81616.1 - 5.1e-14 52.6 0.0 6.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81616.1 - 2.4e-06 27.3 0.2 3.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81616.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 GAO81617.1 - 1.8e-65 221.2 0.0 2.4e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2771 PF10969.3 GAO81617.1 - 0.024 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) Nitrate_red_gam PF02665.9 GAO81617.1 - 0.027 13.8 0.2 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Nitrate reductase gamma subunit p450 PF00067.17 GAO81618.1 - 8.2e-65 219.1 0.0 1e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_1 PF13243.1 GAO81619.1 - 4.6e-31 107.0 0.0 5.4e-18 65.0 0.0 5.0 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 GAO81619.1 - 2.2e-29 100.7 8.2 6.7e-09 35.1 1.5 5.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAO81619.1 - 7.8e-28 97.1 0.2 3.6e-16 59.5 0.1 5.1 2 2 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 GAO81619.1 - 5e-11 42.2 0.1 8.7e-05 21.8 0.0 4.9 3 1 2 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 GAO81619.1 - 0.0012 18.1 0.0 0.05 12.8 0.0 3.2 2 1 0 3 3 3 1 A-macroglobulin complement component GMC_oxred_C PF05199.8 GAO81620.1 - 6.5e-18 65.4 0.0 1.2e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAO81620.1 - 5.9e-07 28.9 0.0 5.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAO81620.1 - 5.7e-05 23.0 1.6 0.00025 21.0 1.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO81620.1 - 6.7e-05 21.9 5.6 0.0014 17.5 3.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO81620.1 - 0.00061 19.7 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO81620.1 - 0.00081 18.3 3.3 0.2 10.5 1.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO81620.1 - 0.00082 18.5 0.6 0.0023 17.0 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.13 GAO81620.1 - 0.0066 14.8 0.1 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.22 GAO81620.1 - 0.012 16.0 0.1 0.032 14.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO81620.1 - 0.015 14.2 0.2 0.032 13.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 GAO81620.1 - 0.028 13.5 0.2 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 GAO81620.1 - 0.21 10.0 1.3 0.33 9.3 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 GAO81620.1 - 0.29 9.9 0.7 0.88 8.3 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAO81620.1 - 0.74 8.8 3.2 1.3 7.9 2.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4246 PF14033.1 GAO81622.1 - 5.2e-183 609.2 0.0 6.3e-183 608.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PRP1_N PF06424.7 GAO81622.1 - 0.024 14.9 2.8 0.085 13.1 0.1 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal 2OG-FeII_Oxy_5 PF13759.1 GAO81622.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Pyr_redox_2 PF07992.9 GAO81624.1 - 9.1e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO81624.1 - 0.002 17.1 0.0 0.63 8.9 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAO81624.1 - 0.0022 17.7 1.0 1.4 8.6 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GARS_N PF02844.10 GAO81624.1 - 0.0033 17.8 0.1 0.097 13.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain Thi4 PF01946.12 GAO81624.1 - 0.0051 15.9 0.0 0.033 13.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAO81624.1 - 0.0054 15.6 0.8 0.0087 14.9 0.2 1.7 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAO81624.1 - 0.0079 15.2 2.9 0.069 12.1 0.5 2.4 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 GAO81624.1 - 0.021 14.8 0.2 0.047 13.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO81624.1 - 0.029 14.4 0.4 2 8.3 0.1 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO81624.1 - 0.11 11.4 1.9 0.28 10.0 1.3 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Response_reg PF00072.19 GAO81625.1 - 4.9e-23 81.2 0.1 1.4e-22 79.8 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAO81625.1 - 1.7e-16 59.8 0.0 3.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAO81625.1 - 2.2e-12 46.8 0.0 7.9e-12 45.0 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 GAO81625.1 - 1.5e-05 25.4 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 GAO81625.1 - 0.00013 22.0 0.0 0.0012 18.9 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 GAO81625.1 - 0.00022 21.3 0.1 0.00082 19.5 0.0 2.0 2 0 0 2 2 2 1 GAF domain NAD_binding_10 PF13460.1 GAO81626.1 - 2.7e-06 27.5 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO81626.1 - 0.007 15.3 0.0 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 GAO81626.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MIP PF00230.15 GAO81627.1 - 2.8e-42 144.7 9.0 4e-42 144.2 6.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein Herpes_UL45 PF05473.7 GAO81628.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UL45 protein ADH_zinc_N PF00107.21 GAO81629.1 - 9.2e-09 34.9 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81629.1 - 2.9e-07 30.2 0.0 5.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1295 PF06966.7 GAO81630.1 - 1.3e-12 47.5 0.1 1.7e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 GAO81630.1 - 0.0034 15.9 0.8 0.0059 15.1 0.5 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 GAO81630.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase SRP54 PF00448.17 GAO81630.1 - 0.068 12.5 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Epimerase PF01370.16 GAO81631.1 - 9.4e-24 84.1 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO81631.1 - 1.9e-16 59.6 0.0 2.5e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO81631.1 - 5.1e-11 41.9 0.4 7.4e-10 38.1 0.3 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAO81631.1 - 9.2e-11 42.0 0.0 1.6e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO81631.1 - 2.6e-09 37.2 0.0 4.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81631.1 - 7.5e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO81631.1 - 0.00018 20.5 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAO81631.1 - 0.00055 19.2 0.0 0.0018 17.5 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 GAO81631.1 - 0.0063 16.8 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAO81631.1 - 0.016 14.1 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain DUF4621 PF15414.1 GAO81631.1 - 0.034 12.8 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Saccharop_dh PF03435.13 GAO81631.1 - 0.054 12.4 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DJ-1_PfpI PF01965.19 GAO81632.1 - 7.6e-23 80.5 0.0 2.1e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAO81632.1 - 3.8e-08 32.7 0.0 8.1e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family EthD PF07110.6 GAO81633.1 - 0.06 14.2 0.3 0.18 12.7 0.2 1.7 1 1 0 1 1 1 0 EthD domain G-alpha PF00503.15 GAO81634.1 - 8.2e-31 107.0 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit F-box-like PF12937.2 GAO81635.1 - 4.4e-07 29.5 0.1 8.7e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81635.1 - 0.0055 16.3 0.5 0.091 12.4 0.1 2.7 2 0 0 2 2 2 1 F-box domain NUC130_3NT PF08158.7 GAO81635.1 - 0.08 13.2 0.1 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 NUC130/3NT domain Sigma70_ner PF04546.8 GAO81635.1 - 0.094 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region ADH_N PF08240.7 GAO81636.1 - 2.8e-12 46.3 0.0 5.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81636.1 - 1.7e-11 43.7 0.2 2.6e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_32N PF00251.15 GAO81637.1 - 2.9e-130 434.1 6.6 4.5e-71 239.7 1.4 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAO81637.1 - 3.3e-32 110.6 0.2 6.6e-18 64.8 0.1 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAO81637.1 - 0.028 14.2 7.3 1.5 8.9 0.1 4.1 3 0 0 3 3 3 0 BNR/Asp-box repeat Zn_clus PF00172.13 GAO81638.1 - 1.9e-10 40.4 6.1 5.2e-10 39.0 4.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO81638.1 - 0.00033 19.6 1.1 0.0073 15.2 0.5 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2961 PF11175.3 GAO81639.1 - 4.1e-88 294.6 5.2 5.2e-88 294.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Sugar_tr PF00083.19 GAO81640.1 - 8.2e-76 255.3 21.0 1.3e-75 254.7 14.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81640.1 - 1.1e-15 57.1 26.6 1.1e-15 57.1 18.4 1.9 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF2149 PF09919.4 GAO81640.1 - 0.16 12.0 0.4 0.31 11.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) AGTRAP PF06396.6 GAO81640.1 - 2 8.0 8.5 6.8 6.3 0.9 2.3 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Sugar_tr PF00083.19 GAO81641.1 - 1.2e-123 413.0 20.3 1.5e-123 412.7 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81641.1 - 1.6e-23 82.9 22.6 1.6e-23 82.9 15.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily EBP PF05241.7 GAO81641.1 - 0.65 8.9 5.8 1.1 8.1 4.0 1.3 1 0 0 1 1 1 0 Emopamil binding protein Zn_clus PF00172.13 GAO81642.1 - 2e-09 37.2 8.9 4.1e-09 36.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO81642.1 - 0.0011 17.9 0.4 0.0021 16.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 GAO81643.1 - 3.2e-88 296.0 3.9 7.6e-72 242.2 0.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAO81643.1 - 5.3e-19 68.3 0.1 1.7e-18 66.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal TLD PF07534.11 GAO81645.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 TLD PP2C PF00481.16 GAO81646.1 - 3.5e-41 141.2 0.1 4.3e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAO81646.1 - 7e-09 35.3 0.0 3.3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAO81646.1 - 0.0011 18.6 0.3 0.063 12.9 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Hemerythrin PF01814.18 GAO81647.1 - 3e-15 56.5 1.6 4.2e-15 56.0 1.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NmrA PF05368.8 GAO81648.1 - 4.4e-06 26.1 0.0 1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81648.1 - 8.6e-06 25.8 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding fn3 PF00041.16 GAO81650.1 - 4.9e-13 49.0 11.3 6.1e-07 29.4 0.2 4.1 4 1 0 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 GAO81650.1 - 1e-08 35.4 0.7 2.7e-07 30.8 0.0 2.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO81650.1 - 9.8e-07 28.8 0.2 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase PNP_UDP_1 PF01048.15 GAO81651.1 - 1.2e-11 44.0 0.1 4.6e-11 42.1 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAO81652.1 - 8.1e-60 199.1 0.0 9.4e-14 51.5 0.0 5.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81652.1 - 2e-37 126.9 0.4 3.6e-08 33.7 0.0 7.8 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.25 GAO81652.1 - 4.7e-35 117.6 0.0 7.3e-06 25.5 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAO81652.1 - 1.3e-33 114.2 0.0 1e-08 35.1 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81652.1 - 1.6e-26 89.7 0.0 0.0019 18.2 0.0 9.0 8 0 0 8 8 8 5 Ankyrin repeat PNP_UDP_1 PF01048.15 GAO81652.1 - 2.1e-13 49.7 0.0 4.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO81652.1 - 0.00016 21.4 0.1 0.00055 19.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 GAO81652.1 - 0.0041 17.3 0.0 0.059 13.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 GAO81652.1 - 0.026 13.5 0.4 0.47 9.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 GAO81652.1 - 0.039 14.0 0.0 0.22 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO81652.1 - 0.089 11.6 0.0 2 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain adh_short_C2 PF13561.1 GAO81653.1 - 1.8e-24 86.8 0.0 2.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81653.1 - 1.7e-22 80.1 0.5 2e-22 79.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81653.1 - 4.1e-13 49.3 0.1 5e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81653.1 - 0.00012 21.5 0.1 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1399 PF07173.7 GAO81654.1 - 1.2e-19 70.9 0.1 1.3e-17 64.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Fungal_trans_2 PF11951.3 GAO81654.1 - 1.1e-05 24.2 0.0 2.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 GAO81656.1 - 0.0081 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain DDE_1 PF03184.14 GAO81657.1 - 4.8e-13 48.7 0.0 9.9e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 GAO81657.1 - 2.3e-11 43.0 2.8 2.8e-11 42.7 0.1 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 GAO81657.1 - 2.5e-11 43.2 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain UPF0175 PF03683.8 GAO81657.1 - 0.0006 19.2 0.1 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) Sugar_tr PF00083.19 GAO81658.1 - 4.1e-124 414.5 19.2 4.8e-124 414.3 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81658.1 - 1.4e-21 76.6 23.3 1.4e-21 76.6 16.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Codanin-1_C PF15296.1 GAO81659.1 - 0.02 14.7 1.2 0.075 12.9 0.0 2.5 3 0 0 3 3 3 0 Codanin-1 C-terminus Herpes_US12 PF05363.7 GAO81659.1 - 0.041 14.3 1.1 0.12 12.9 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus US12 family CK_II_beta PF01214.13 GAO81659.1 - 0.11 11.9 0.8 0.36 10.3 0.2 2.0 2 0 0 2 2 2 0 Casein kinase II regulatory subunit zf-C2H2_4 PF13894.1 GAO81659.1 - 0.25 11.7 3.9 0.66 10.4 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger GFA PF04828.9 GAO81660.1 - 2.8e-09 36.7 0.9 2.8e-09 36.7 0.6 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CodY PF06018.9 GAO81660.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 CodY GAF-like domain zf-CSL PF05207.8 GAO81660.1 - 0.4 10.2 4.9 0.21 11.1 1.0 2.1 2 0 0 2 2 2 0 CSL zinc finger PTR2 PF00854.16 GAO81661.1 - 6.3e-31 107.4 7.6 6.3e-31 107.4 5.3 1.4 2 0 0 2 2 2 1 POT family MFS_1 PF07690.11 GAO81661.1 - 2.6e-09 36.2 26.3 2.6e-09 36.2 18.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 GAO81661.1 - 0.0047 16.9 10.4 0.19 11.8 0.7 3.9 3 1 0 3 3 3 1 2TM domain CcmH PF03918.9 GAO81661.1 - 0.091 11.7 0.2 1.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF2058 PF09831.4 GAO81662.1 - 1.6 8.5 9.1 2.2 8.1 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) IncA PF04156.9 GAO81662.1 - 1.7 8.2 6.9 2 7.9 4.8 1.1 1 0 0 1 1 1 0 IncA protein SurE PF01975.12 GAO81664.1 - 3.8e-36 124.2 1.6 4.8e-36 123.9 0.9 1.2 1 1 0 1 1 1 1 Survival protein SurE DUF3360 PF11840.3 GAO81664.1 - 0.097 10.9 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) adh_short PF00106.20 GAO81665.1 - 2.6e-14 53.4 0.4 3.6e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81665.1 - 7.6e-07 28.9 0.2 1.2e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO81665.1 - 5.4e-06 26.3 0.1 8.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO81665.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4322 PF14210.1 GAO81665.1 - 0.041 13.3 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) Transferase PF02458.10 GAO81666.1 - 4.8e-17 61.5 0.0 1.9e-15 56.2 0.0 2.7 1 1 0 1 1 1 1 Transferase family TPR_12 PF13424.1 GAO81667.1 - 5.6e-20 71.0 1.3 7.7e-10 38.5 0.0 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAO81667.1 - 2.8e-14 52.4 0.3 3.6e-06 26.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO81667.1 - 0.069 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.1 GAO81667.1 - 0.13 12.1 0.2 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 GAO81669.1 - 1.5e-85 285.6 50.0 9.4e-49 165.4 11.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAO81669.1 - 1e-39 135.9 0.0 6.9e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO81669.1 - 8.6e-24 83.1 8.2 6e-23 80.4 0.0 3.3 4 0 0 4 4 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAO81669.1 - 5.6e-09 35.4 13.5 5.6e-09 35.4 9.4 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.1 GAO81669.1 - 7.3e-07 29.3 0.1 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAO81669.1 - 3.2e-05 24.0 0.0 0.008 16.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 GAO81669.1 - 0.00018 21.5 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAO81669.1 - 0.00036 19.7 0.0 0.0066 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAO81669.1 - 0.00041 20.6 0.0 0.071 13.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 GAO81669.1 - 0.00083 18.8 0.1 0.061 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAO81669.1 - 0.00084 18.9 0.3 0.095 12.3 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 GAO81669.1 - 0.0024 17.6 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_28 PF13521.1 GAO81669.1 - 0.0024 17.8 0.1 0.043 13.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 GAO81669.1 - 0.0031 17.0 0.2 0.037 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 GAO81669.1 - 0.0046 16.4 0.0 0.41 10.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAO81669.1 - 0.006 17.3 0.0 0.045 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO81669.1 - 0.009 15.7 0.0 1.8 8.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 GAO81669.1 - 0.021 14.7 0.0 0.19 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 GAO81669.1 - 0.034 13.8 0.0 0.94 9.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 GAO81669.1 - 0.044 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 GAO81669.1 - 0.053 12.9 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 GAO81669.1 - 0.055 12.9 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 GAO81669.1 - 0.074 13.0 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 GAO81669.1 - 0.087 13.3 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PDR_assoc PF08370.6 GAO81669.1 - 0.19 11.2 7.2 0.02 14.3 1.0 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ArgK PF03308.11 GAO81669.1 - 0.33 9.6 0.0 0.76 8.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein DUF1129 PF06570.6 GAO81669.1 - 1.4 8.2 4.2 1 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) adh_short_C2 PF13561.1 GAO81670.1 - 4.7e-36 124.7 0.1 5.4e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81670.1 - 6.5e-35 120.5 2.3 1.1e-34 119.8 1.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81670.1 - 5.4e-15 55.5 1.6 7.7e-15 55.0 1.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO81670.1 - 4.7e-05 23.4 0.7 8.6e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 GAO81670.1 - 0.00028 20.1 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAO81670.1 - 0.0033 16.9 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAO81670.1 - 0.031 13.3 0.3 0.071 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TetR_N PF00440.18 GAO81670.1 - 0.044 13.4 1.0 1.8 8.2 0.0 3.6 4 1 1 5 5 5 0 Bacterial regulatory proteins, tetR family AdoHcyase_NAD PF00670.16 GAO81670.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAO81670.1 - 0.13 12.0 3.9 0.11 12.3 0.6 2.4 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SyrA PF11089.3 GAO81670.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 Exopolysaccharide production repressor HEAT_2 PF13646.1 GAO81671.1 - 6.8e-26 90.3 15.3 2.6e-06 27.5 1.3 6.2 1 1 3 6 6 6 5 HEAT repeats HEAT PF02985.17 GAO81671.1 - 2.6e-18 64.3 10.7 0.32 11.2 0.0 10.2 10 0 0 10 10 10 3 HEAT repeat NACHT PF05729.7 GAO81671.1 - 7.6e-16 58.2 0.2 3.1e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Cohesin_HEAT PF12765.2 GAO81671.1 - 7.3e-07 29.0 6.9 0.015 15.2 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 GAO81671.1 - 2.5e-06 27.8 17.0 0.67 10.5 0.0 7.9 4 2 4 8 8 8 4 HEAT-like repeat NB-ARC PF00931.17 GAO81671.1 - 4.2e-06 25.8 0.0 1.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Adaptin_N PF01602.15 GAO81671.1 - 1.6e-05 23.4 6.2 0.0034 15.7 0.1 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm PF00514.18 GAO81671.1 - 3e-05 23.6 0.2 2 8.3 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 GAO81671.1 - 3.5e-05 23.7 1.1 2.7 7.7 0.0 5.1 3 2 2 5 5 4 1 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.1 GAO81671.1 - 0.001 19.2 0.2 0.0073 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rrf2 PF02082.15 GAO81671.1 - 0.0018 18.3 8.0 7.5 6.7 0.2 5.7 2 2 5 7 7 7 1 Transcriptional regulator AAA_10 PF12846.2 GAO81671.1 - 0.016 14.6 0.3 1 8.7 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain TolA PF06519.6 GAO81671.1 - 0.018 15.0 0.3 23 5.0 0.0 4.3 4 1 2 6 6 5 0 TolA C-terminal AAA_18 PF13238.1 GAO81671.1 - 0.021 15.1 1.0 0.11 12.8 0.0 2.8 4 0 0 4 4 2 0 AAA domain VHS PF00790.14 GAO81671.1 - 0.057 13.0 7.9 2.7 7.6 0.2 4.5 4 1 1 5 5 5 0 VHS domain AAA_17 PF13207.1 GAO81671.1 - 0.1 13.4 0.0 0.69 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAO81671.1 - 0.19 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IFRD PF05004.8 GAO81671.1 - 0.24 10.4 7.9 21 4.0 0.1 5.0 1 1 4 6 6 6 0 Interferon-related developmental regulator (IFRD) AAA_16 PF13191.1 GAO81671.1 - 0.54 10.2 0.0 0.54 10.2 0.0 4.3 3 2 0 4 4 3 0 AAA ATPase domain Pentapeptide PF00805.17 GAO81672.1 - 0.019 14.2 0.1 0.068 12.4 0.1 1.9 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF1263 PF06882.7 GAO81672.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Response_reg PF00072.19 GAO81673.1 - 2.5e-21 75.7 0.1 4.7e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAO81673.1 - 1.4e-20 73.0 0.1 2.7e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAO81673.1 - 1.2e-12 47.6 0.3 3.3e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 GAO81673.1 - 5.9e-06 26.4 0.2 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain Peptidase_M75 PF09375.5 GAO81673.1 - 0.066 12.5 0.2 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Imelysin Fungal_trans PF04082.13 GAO81674.1 - 3.8e-11 42.3 0.3 2.3e-10 39.8 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81674.1 - 1.8e-09 37.3 14.9 3.9e-09 36.2 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAO81675.1 - 7.1e-35 120.3 30.6 1.9e-34 118.9 20.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1542 PF07564.6 GAO81675.1 - 0.048 13.6 0.1 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Sugar_tr PF00083.19 GAO81676.1 - 1.3e-79 267.9 20.4 1.7e-79 267.5 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81676.1 - 4.5e-19 68.3 39.1 6.1e-18 64.6 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4646 PF15496.1 GAO81677.1 - 1.1e-18 67.4 0.2 5.1e-18 65.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 GAO81677.1 - 0.059 13.2 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ISN1 PF06437.6 GAO81678.1 - 1.3e-181 603.8 0.0 1.7e-181 603.4 0.0 1.2 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ead_Ea22 PF13935.1 GAO81678.1 - 0.16 12.3 0.8 1.7 9.0 0.0 2.5 3 0 0 3 3 3 0 Ead/Ea22-like protein PFK PF00365.15 GAO81679.1 - 9.5e-166 549.7 0.5 2.2e-119 397.6 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 GAO81679.1 - 0.013 14.3 0.1 1.3 7.7 0.1 2.2 2 0 0 2 2 2 0 ATP-NAD kinase DUF4646 PF15496.1 GAO81679.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) FAM216B PF15107.1 GAO81679.1 - 0.18 11.6 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 FAM216B protein family Med17 PF10156.4 GAO81680.1 - 7.2e-133 443.2 0.0 9.1e-133 442.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex CorA PF01544.13 GAO81681.1 - 1.1e-37 129.6 0.0 1.6e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short PF00106.20 GAO81681.1 - 1.3e-28 100.0 1.1 2.5e-28 99.0 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81681.1 - 8.6e-14 51.5 0.3 2.1e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO81681.1 - 0.00073 19.2 0.1 0.0021 17.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO81681.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 GAO81682.1 - 2.9e-30 105.1 22.2 2.9e-30 105.1 15.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 GAO81683.1 - 2.1e-12 47.2 0.2 7.5e-11 42.2 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO81683.1 - 6e-09 35.8 0.0 8.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81683.1 - 3.4e-05 23.4 0.3 0.0037 16.7 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO81683.1 - 0.00026 19.7 0.0 0.00033 19.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 GAO81683.1 - 0.00044 20.0 0.0 0.088 12.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO81683.1 - 0.0014 18.7 0.2 0.04 13.9 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding F-box-like PF12937.2 GAO81684.1 - 2.7e-11 43.0 1.3 6.9e-11 41.6 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO81684.1 - 1.4e-06 27.7 0.2 3.9e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 F-box domain YpzI PF14140.1 GAO81686.1 - 0.94 9.0 10.2 18 4.9 0.0 3.8 4 0 0 4 4 4 0 YpzI-like protein HsbA PF12296.3 GAO81687.1 - 8.5e-34 116.0 5.7 8.5e-34 116.0 3.9 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A HNH_2 PF13391.1 GAO81688.1 - 1.4e-05 24.7 0.2 2.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease DDE_Tnp_1_6 PF13751.1 GAO81688.1 - 0.15 12.0 0.3 0.25 11.3 0.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC PF00098.18 GAO81689.1 - 0.0037 17.1 3.5 0.0059 16.4 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 GAO81689.1 - 0.0052 16.4 0.4 0.015 15.0 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 GAO81689.1 - 0.049 13.2 1.2 0.072 12.7 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 GAO81689.1 - 0.081 12.4 6.3 0.17 11.4 4.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HCV_NS5a_C PF12941.2 GAO81689.1 - 0.23 11.0 2.0 0.3 10.6 1.4 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region GTPase_Cys_C PF12631.2 GAO81689.1 - 0.84 10.0 4.6 1.9 8.9 2.9 1.7 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE REV PF00424.13 GAO81689.1 - 1.3 8.9 17.3 0.054 13.3 8.1 1.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CAP_N PF01213.14 GAO81690.1 - 0.14 11.4 0.4 0.16 11.2 0.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ACC_epsilon PF13822.1 GAO81690.1 - 0.97 9.8 5.6 0.27 11.5 0.8 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit HNH_2 PF13391.1 GAO81691.1 - 0.00059 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_61 PF03443.9 GAO81694.1 - 1.3e-83 280.1 0.5 1.3e-83 280.1 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAO81694.1 - 2.3e-13 49.5 12.4 5.5e-13 48.3 8.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.17 GAO81694.1 - 0.0055 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Rrn6 PF10214.4 GAO81694.1 - 6.8 4.6 5.1 9.3 4.2 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor p450 PF00067.17 GAO81695.1 - 8.7e-53 179.4 0.0 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_3 PF13469.1 GAO81697.1 - 0.0023 18.9 1.4 0.0041 18.0 0.8 1.6 1 1 0 1 1 1 1 Sulfotransferase family adh_short PF00106.20 GAO81699.1 - 5.2e-22 78.5 0.0 6.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81699.1 - 5.9e-09 36.0 0.0 7.1e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81699.1 - 1.1e-07 31.7 0.0 2.5e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO81699.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAO81699.1 - 0.09 12.1 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO81699.1 - 0.096 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DLH PF01738.13 GAO81700.1 - 8.8e-32 110.1 0.0 1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO81700.1 - 6.9e-07 29.1 0.0 9.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81700.1 - 0.041 13.7 0.0 0.33 10.8 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.6 GAO81700.1 - 0.13 11.2 0.0 0.64 9.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 GAO81701.1 - 2.4e-40 138.3 28.7 2.4e-40 138.3 19.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81701.1 - 1e-10 40.8 28.0 1.5e-10 40.2 19.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_4 PF13637.1 GAO81703.1 - 6.7e-22 77.4 5.7 0.0073 16.8 0.0 9.8 6 5 5 11 11 11 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO81703.1 - 7.7e-21 74.2 0.7 2.3e-07 31.0 0.0 6.8 4 3 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81703.1 - 8.5e-19 66.3 4.2 3.8e-05 23.2 0.0 9.1 8 2 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 GAO81703.1 - 1.3e-14 53.8 9.4 0.0041 17.3 0.0 8.1 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81703.1 - 4e-11 42.0 3.8 1.5 9.3 0.0 9.2 9 3 0 10 10 10 2 Ankyrin repeat Ribonuclease PF00545.15 GAO81704.1 - 1e-23 83.1 12.8 4.2e-13 49.1 0.2 3.4 2 1 0 2 2 2 2 ribonuclease Acetyltransf_10 PF13673.1 GAO81704.1 - 0.092 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1510 PF07423.6 GAO81704.1 - 0.15 11.3 21.5 0.13 11.6 12.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 GAO81704.1 - 6.3 5.8 7.9 9.3 5.3 5.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 GAO81704.1 - 8.9 3.8 5.9 11 3.5 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3632 PF12311.3 GAO81705.1 - 2.5e-30 105.6 1.6 3.4e-30 105.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) LtrA PF06772.6 GAO81706.1 - 0.032 13.1 5.7 0.058 12.2 1.5 2.4 1 1 2 3 3 3 0 Bacterial low temperature requirement A protein (LtrA) Cytochrom_B_C PF00032.12 GAO81706.1 - 0.6 10.3 3.8 0.8 9.9 0.6 2.6 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF4396 PF14342.1 GAO81706.1 - 4.1 7.4 6.9 1 9.5 0.4 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4396) AA_permease_2 PF13520.1 GAO81707.1 - 1.8e-52 178.3 49.2 2.1e-52 178.0 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO81707.1 - 8.7e-28 96.8 42.2 1.2e-27 96.4 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease Tmemb_18A PF09771.4 GAO81707.1 - 0.86 9.5 5.3 10 6.1 0.1 2.8 2 0 0 2 2 2 0 Transmembrane protein 188 DUF2189 PF09955.4 GAO81708.1 - 0.018 14.9 0.2 0.018 14.9 0.2 3.3 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) YqhR PF11085.3 GAO81708.1 - 0.11 11.9 5.5 0.2 11.2 3.2 1.9 1 1 0 1 1 1 0 Conserved membrane protein YqhR DUF1761 PF08570.5 GAO81708.1 - 1.9 8.5 10.3 1.1 9.3 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) BCD PF15461.1 GAO81708.1 - 3.3 7.0 18.8 0.12 11.8 6.5 2.7 1 1 2 3 3 3 0 Beta-carotene 15,15'-dioxygenase BCS1_N PF08740.6 GAO81709.1 - 1.6e-45 155.0 0.0 2.3e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAO81709.1 - 4.9e-17 62.3 0.0 9.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAO81709.1 - 0.00011 22.9 0.1 0.00079 20.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 GAO81709.1 - 0.00027 20.6 0.0 0.0012 18.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO81709.1 - 0.00084 19.3 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 GAO81709.1 - 0.0021 17.5 0.0 0.0077 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 GAO81709.1 - 0.073 13.3 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 GAO81709.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 GAO81709.1 - 0.085 12.4 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAO81709.1 - 0.11 11.4 0.7 0.26 10.1 0.0 2.0 3 1 0 3 3 3 0 Protein of unknown function (DUF815) TIP49 PF06068.8 GAO81709.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus CBM_4_9 PF02018.12 GAO81710.1 - 2.8e-11 43.5 0.0 3.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain MAM PF00629.18 GAO81710.1 - 0.00065 19.5 0.0 0.00077 19.2 0.0 1.1 1 0 0 1 1 1 1 MAM domain DUF4307 PF14155.1 GAO81711.1 - 0.95 9.2 5.0 4 7.2 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4307) Epimerase PF01370.16 GAO81712.1 - 3.3e-10 39.7 0.0 3.1e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81712.1 - 7.9e-09 35.7 0.0 1.7e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO81712.1 - 5.3e-05 23.1 0.2 0.0001 22.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO81712.1 - 0.00013 21.0 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 GAO81712.1 - 0.00028 20.2 0.0 0.0012 18.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 GAO81712.1 - 0.003 16.4 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 GAO81712.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAO81712.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 GAO81712.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAO81712.1 - 0.063 11.9 0.0 2 7.0 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAO81712.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GXWXG PF14231.1 GAO81713.1 - 7.2e-21 73.5 0.1 1.4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 GXWXG protein DUF4334 PF14232.1 GAO81713.1 - 3.2e-17 61.8 0.2 5e-16 58.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) MFS_1 PF07690.11 GAO81713.1 - 6.4e-11 41.5 18.9 6.4e-11 41.5 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.15 GAO81714.1 - 1.9e-14 53.4 0.0 6.1e-09 35.3 0.0 3.0 1 1 2 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Epimerase PF01370.16 GAO81715.1 - 7.3e-09 35.4 0.0 9.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81715.1 - 0.00025 21.1 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO81715.1 - 0.0019 18.1 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO81715.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 GAO81715.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAO81716.1 - 1.4e-15 57.3 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO81716.1 - 3.1e-11 42.6 0.0 9.8e-11 41.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAO81716.1 - 8.4e-10 38.9 0.1 3.6e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO81716.1 - 2.1e-07 29.9 0.0 2.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO81716.1 - 0.00066 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 GAO81717.1 - 1.5e-11 43.6 0.0 2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BPD_transp_1 PF00528.17 GAO81718.1 - 0.073 12.5 11.9 0.16 11.4 8.3 1.6 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component PDR_assoc PF08370.6 GAO81718.1 - 0.079 12.4 1.5 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Nairovirus_M PF07948.6 GAO81718.1 - 0.14 10.2 0.1 0.17 9.9 0.1 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like NmrA PF05368.8 GAO81719.1 - 3e-21 75.7 0.0 3.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81719.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Abhydrolase_6 PF12697.2 GAO81720.1 - 2.3e-28 99.6 0.3 3.1e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81720.1 - 2.9e-06 27.0 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81720.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAO81720.1 - 0.028 12.9 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.16 GAO81720.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Aminotran_4 PF01063.14 GAO81721.1 - 1.8e-20 73.4 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV ApbA_C PF08546.6 GAO81722.1 - 1.8e-29 102.3 0.1 3.5e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAO81722.1 - 5e-27 94.2 0.0 7.6e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 GAO81723.1 - 5.7e-17 61.4 0.1 1.2e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81723.1 - 3.4e-05 23.6 2.6 9.8e-05 22.1 1.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_7 PF13499.1 GAO81726.1 - 1.1e-06 28.7 0.2 1.4e-06 28.3 0.2 1.3 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAO81726.1 - 3.7e-06 26.9 1.6 6.7e-06 26.1 1.1 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 GAO81726.1 - 0.00011 21.1 0.1 0.0082 15.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAO81726.1 - 0.00016 21.2 0.4 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 GAO81726.1 - 0.0042 16.3 0.0 0.012 14.8 0.0 1.8 1 0 0 1 1 1 1 EF hand DUF3863 PF12979.2 GAO81726.1 - 0.0052 15.4 0.0 0.0063 15.1 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3863) EF-hand_8 PF13833.1 GAO81726.1 - 0.071 12.7 0.9 2.8 7.6 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 GAO81727.1 - 4.3e-07 29.9 0.0 6.4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO81727.1 - 3e-05 22.9 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAO81727.1 - 0.00055 19.5 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.4 GAO81727.1 - 0.0047 16.9 0.1 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 GAO81727.1 - 0.029 13.6 0.0 0.075 12.4 0.0 1.7 1 0 0 1 1 1 0 EF hand RGS PF00615.14 GAO81728.1 - 6.3e-07 29.5 0.0 4.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain AMP-binding PF00501.23 GAO81729.1 - 4e-13 48.5 0.0 6.2e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAO81729.1 - 1.6e-08 33.7 0.0 4.3e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Condensation domain Mito_carr PF00153.22 GAO81730.1 - 9e-60 198.4 10.1 1.5e-20 72.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 GAO81731.1 - 2.2e-30 105.4 4.2 6.6e-30 103.8 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81731.1 - 5.3e-09 35.8 9.1 8.9e-09 35.1 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.8 GAO81732.1 - 2.3e-93 312.8 1.1 3.9e-92 308.8 0.7 1.9 1 1 0 1 1 1 1 PrpF protein Sugar_tr PF00083.19 GAO81733.1 - 2e-92 310.1 16.7 2.4e-92 309.8 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81733.1 - 6.6e-19 67.8 14.4 6.6e-19 67.8 10.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 GAO81733.1 - 0.19 11.7 0.0 0.19 11.7 0.0 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.19 GAO81734.1 - 2.6e-45 154.8 6.4 3.6e-45 154.3 4.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81734.1 - 3.1e-12 45.8 13.7 4e-12 45.5 9.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81735.1 - 7.8e-40 136.7 14.4 8.8e-40 136.6 10.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81735.1 - 8.6e-05 21.4 10.6 0.00011 21.1 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.13 GAO81736.1 - 6.3e-38 130.3 35.3 7.8e-38 130.0 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.6 GAO81736.1 - 0.013 14.8 0.9 0.013 14.8 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) TB2_DP1_HVA22 PF03134.14 GAO81736.1 - 0.12 12.0 5.3 0.46 10.2 3.7 2.0 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Ank_2 PF12796.2 GAO81737.1 - 8.3e-13 48.4 0.0 2e-07 31.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81737.1 - 1e-10 40.8 0.2 0.00037 20.1 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAO81737.1 - 1.6e-06 28.4 0.0 0.037 14.5 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81737.1 - 7.9e-05 22.7 0.0 0.075 13.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81737.1 - 0.0002 21.3 0.0 2.8 8.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Zn_clus PF00172.13 GAO81738.1 - 0.00059 19.6 12.1 0.00059 19.6 8.4 2.4 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SecG PF03840.9 GAO81738.1 - 0.056 13.1 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit MAP2_projctn PF08377.5 GAO81738.1 - 0.24 8.8 0.0 0.34 8.4 0.0 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain Trp_halogenase PF04820.9 GAO81739.1 - 2.4e-12 46.2 0.0 1.4e-08 33.7 0.0 3.2 2 1 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 GAO81739.1 - 0.00095 18.1 0.1 0.0018 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO81739.1 - 0.0046 16.0 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81739.1 - 0.0097 15.9 0.3 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-ribbon_3 PF13248.1 GAO81739.1 - 0.01 15.0 1.5 0.025 13.8 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HI0933_like PF03486.9 GAO81739.1 - 0.017 13.6 0.2 0.026 13.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAO81739.1 - 0.031 13.1 0.6 0.59 8.9 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DZR PF12773.2 GAO81739.1 - 0.18 11.6 2.0 0.4 10.5 1.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon DAHP_synth_1 PF00793.15 GAO81740.1 - 1.4e-85 286.3 0.0 1.7e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family GST_N PF02798.15 GAO81741.1 - 1.2e-12 47.7 0.0 3.2e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO81741.1 - 6.3e-11 42.1 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO81741.1 - 1.9e-10 40.8 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO81741.1 - 6.5e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO81741.1 - 2e-07 30.8 0.1 4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO81741.1 - 0.015 15.7 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAO81741.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain DIT1_PvcA PF05141.7 GAO81742.1 - 1.3e-88 296.9 0.0 1.8e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein FAM110_N PF14161.1 GAO81742.1 - 0.18 12.1 0.3 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Centrosome-associated N terminus DUF4066 PF13278.1 GAO81744.1 - 7.6e-24 83.8 0.0 1.2e-23 83.2 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO81744.1 - 3.5e-15 55.7 0.0 4.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 GAO81744.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Zn_clus PF00172.13 GAO81745.1 - 5.5e-06 26.1 11.8 1e-05 25.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.1 GAO81746.1 - 1e-29 102.3 0.0 2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO81746.1 - 1.1e-14 53.8 0.0 2.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO81746.1 - 1.4e-08 35.4 0.0 3.4e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAO81746.1 - 1.8e-05 25.0 0.3 0.078 13.1 0.1 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DIT1_PvcA PF05141.7 GAO81747.1 - 2.1e-69 233.9 0.0 1.8e-68 230.8 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 GAO81747.1 - 8.6e-35 120.6 0.1 1.6e-34 119.7 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAO81748.1 - 1.9e-32 112.3 27.9 1.9e-32 112.3 19.3 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81748.1 - 4.3e-12 45.3 14.0 4.3e-12 45.3 9.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter SID-1_RNA_chan PF13965.1 GAO81748.1 - 0.25 9.4 0.9 0.46 8.5 0.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_1 PF07690.11 GAO81749.1 - 1.1e-32 113.1 86.4 1.6e-27 96.1 46.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81749.1 - 1.5e-05 23.7 39.7 0.00087 17.9 6.5 3.5 3 1 1 4 4 4 3 Sugar (and other) transporter MFS_2 PF13347.1 GAO81749.1 - 0.0026 16.2 7.7 0.0026 16.2 5.3 4.5 1 1 3 5 5 5 2 MFS/sugar transport protein DUF4246 PF14033.1 GAO81750.1 - 1.5e-26 93.1 0.0 1.7e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_2 PF12796.2 GAO81751.1 - 1.6e-47 159.7 2.5 3.4e-18 65.7 0.0 9.1 4 2 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO81751.1 - 6.6e-39 131.0 6.5 0.00012 22.2 0.1 11.2 10 1 2 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.25 GAO81751.1 - 1.8e-34 115.7 14.6 1.9e-06 27.4 0.0 12.2 15 0 0 15 15 15 8 Ankyrin repeat Ank_4 PF13637.1 GAO81751.1 - 1.9e-31 107.8 4.4 5e-06 26.8 0.0 11.0 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81751.1 - 2.4e-26 89.1 11.3 0.0017 18.4 0.0 11.8 13 0 0 13 13 13 6 Ankyrin repeat Methyltransf_23 PF13489.1 GAO81752.1 - 1.1e-07 31.6 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81752.1 - 1.9e-06 28.4 0.0 1.4e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81752.1 - 0.00017 21.2 0.0 0.51 9.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81752.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81752.1 - 0.0034 17.8 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO81752.1 - 0.011 16.0 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.11 GAO81752.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PTase_Orf2 PF11468.3 GAO81753.1 - 5.7e-82 275.2 0.0 7e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 Fungal_trans_2 PF11951.3 GAO81754.1 - 2.1e-09 36.4 0.0 2.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO81755.1 - 4.4e-28 98.0 62.0 5.7e-15 54.8 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO81755.1 - 0.00013 20.4 18.0 0.00013 20.4 12.5 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 GAO81756.1 - 7.8e-108 360.9 26.0 8.8e-108 360.8 18.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like GerA PF03323.8 GAO81756.1 - 0.33 9.0 1.4 0.77 7.8 1.0 1.6 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Acyl_transf_3 PF01757.17 GAO81758.1 - 5.7e-47 160.1 34.0 6.7e-47 159.9 23.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 GAO81759.1 - 4e-12 46.4 0.0 7.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trp_halogenase PF04820.9 GAO81759.1 - 0.085 11.4 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase RVT_1 PF00078.22 GAO81760.1 - 1.1e-30 106.5 0.0 2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 GAO81760.1 - 6.3e-18 65.3 0.0 1.5e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 GAO81760.1 - 4e-17 61.9 0.5 4e-17 61.9 0.3 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_3 PF13456.1 GAO81760.1 - 2.9e-05 23.7 0.0 9.7e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like DUF3505 PF12013.3 GAO81761.1 - 5.1e-31 107.1 2.3 5.1e-31 107.1 1.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3505) Peptidase_M10 PF00413.19 GAO81763.1 - 5.7e-27 94.3 0.0 9.1e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 GAO81763.1 - 1e-09 38.2 0.0 2.9e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PAS_4 PF08448.5 GAO81763.1 - 0.0055 16.7 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold Metallopep PF12044.3 GAO81763.1 - 0.014 13.8 0.2 0.02 13.3 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 GAO81763.1 - 0.019 15.0 0.5 0.033 14.2 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAO81763.1 - 0.071 13.6 0.9 0.12 12.8 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 GAO81763.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.6 GAO81763.1 - 0.13 11.9 0.2 0.22 11.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.1 GAO81763.1 - 0.14 11.6 0.2 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4231 PF14015.1 GAO81764.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4106 PF13388.1 GAO81764.1 - 4 6.3 5.8 6.2 5.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HTH_psq PF05225.11 GAO81765.1 - 1.9e-05 24.1 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 GAO81765.1 - 0.011 15.6 0.1 0.016 15.1 0.0 1.5 1 1 0 1 1 1 0 Transposase CENP-B_N PF04218.8 GAO81765.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 GAO81765.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 GAO81765.1 - 0.063 12.4 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Phage_CP76 PF06892.6 GAO81765.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) Nitroreductase PF00881.19 GAO81766.1 - 1.6e-09 37.8 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family FSH1 PF03959.8 GAO81767.1 - 2.8e-29 102.1 0.0 3.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAO81767.1 - 3.1e-05 23.7 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family EBV-NA1 PF02905.9 GAO81767.1 - 0.042 13.3 0.1 7.6 6.0 0.0 2.1 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain ketoacyl-synt PF00109.21 GAO81768.1 - 2.6e-60 204.0 0.0 1.2e-59 201.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO81768.1 - 2.9e-34 118.8 2.2 5.1e-32 111.4 0.3 2.7 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO81768.1 - 2.8e-31 107.8 0.0 7.1e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAO81768.1 - 2e-27 95.6 0.0 3.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAO81768.1 - 3.3e-12 46.4 0.2 8.4e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAO81768.1 - 2.1e-08 33.8 0.0 6.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO81768.1 - 8.5e-05 22.5 0.3 0.00042 20.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.18 GAO81768.1 - 0.0011 18.0 0.6 0.0078 15.2 0.0 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain DapB_N PF01113.15 GAO81768.1 - 0.006 16.5 0.1 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAO81768.1 - 0.18 10.4 0.0 0.48 9.0 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.14 GAO81769.1 - 5.4e-20 71.7 1.7 5.1e-19 68.5 1.2 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO81769.1 - 2.6e-05 23.2 3.4 8.2e-05 21.6 2.5 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO81769.1 - 0.0026 18.1 0.9 0.0058 17.0 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO81769.1 - 0.0033 16.3 1.8 0.65 8.7 0.2 2.8 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 GAO81769.1 - 0.022 13.2 0.5 0.071 11.5 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.5 GAO81769.1 - 0.041 12.6 0.0 0.31 9.8 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.2 GAO81769.1 - 0.041 12.9 0.1 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO81769.1 - 0.048 13.5 0.6 0.084 12.7 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO81769.1 - 0.059 13.4 0.7 0.15 12.1 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO81769.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_4 PF13577.1 GAO81770.1 - 8.4e-16 58.0 0.1 9.6e-16 57.8 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain Rop-like PF05082.8 GAO81770.1 - 0.1 12.0 0.4 0.37 10.2 0.1 1.9 2 0 0 2 2 2 0 Rop-like ketoacyl-synt PF00109.21 GAO81771.1 - 2.7e-69 233.4 0.2 1.3e-68 231.2 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAO81771.1 - 4.1e-56 190.3 0.6 1e-55 189.0 0.1 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAO81771.1 - 8.8e-48 163.2 0.1 1.9e-47 162.1 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAO81771.1 - 6.2e-44 149.8 0.0 2.5e-43 147.8 0.0 2.2 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 GAO81771.1 - 1e-36 125.3 0.1 3e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAO81771.1 - 1.6e-30 106.2 0.8 1e-29 103.6 0.0 2.9 4 0 0 4 4 4 1 short chain dehydrogenase Methyltransf_23 PF13489.1 GAO81771.1 - 1.6e-12 47.4 0.0 3.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO81771.1 - 1.8e-12 47.5 0.0 6.4e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO81771.1 - 5.7e-10 38.9 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81771.1 - 5.1e-09 36.5 0.0 1.9e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO81771.1 - 3.1e-07 29.9 0.0 1.5e-06 27.7 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAO81771.1 - 7.5e-07 29.7 0.0 3.7e-06 27.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 GAO81771.1 - 0.0001 22.5 0.3 0.00027 21.1 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAO81771.1 - 0.00024 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 GAO81772.1 - 4.7e-09 36.0 8.6 9.2e-09 35.0 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO81772.1 - 5e-08 32.1 0.1 1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CENP-Q PF13094.1 GAO81772.1 - 0.003 17.5 0.1 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MFS_1 PF07690.11 GAO81773.1 - 1.5e-06 27.1 14.3 1.5e-06 27.1 9.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PsbH PF00737.15 GAO81773.1 - 6.1 6.5 8.9 0.31 10.6 1.1 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein NmrA PF05368.8 GAO81774.1 - 4.2e-17 62.1 0.1 1.2e-16 60.6 0.1 1.7 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81774.1 - 6.8e-13 49.0 0.4 1.3e-12 48.0 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO81774.1 - 1.6e-08 33.9 0.1 2e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAO81774.1 - 0.00089 19.5 0.2 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAO81774.1 - 0.00097 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAO81774.1 - 0.0011 18.8 0.5 0.0038 17.1 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 GAO81774.1 - 0.0032 17.9 0.1 0.0057 17.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 GAO81774.1 - 0.0036 17.6 0.4 0.011 16.1 0.3 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAO81774.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 GAO81774.1 - 0.029 14.3 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.18 GAO81774.1 - 0.034 13.9 0.4 0.071 12.9 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain GARS_N PF02844.10 GAO81774.1 - 0.042 14.3 0.2 0.08 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain KR PF08659.5 GAO81774.1 - 0.08 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 KR domain DUF3405 PF11885.3 GAO81777.1 - 9e-169 561.8 1.0 2e-168 560.6 0.9 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) Arylsulfotran_2 PF14269.1 GAO81777.1 - 3e-08 33.1 0.1 1.3e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.13 GAO81778.1 - 4.5e-10 38.8 1.3 1.4e-09 37.2 0.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 GAO81779.1 - 2.6e-23 81.9 0.8 4.4e-23 81.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81779.1 - 3.5e-13 50.5 0.2 7e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81779.1 - 3.9e-13 49.1 0.1 8.2e-12 44.8 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribonuc_L-PSP PF01042.16 GAO81780.1 - 3.7e-27 94.4 0.5 4.9e-27 94.0 0.3 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Transferase PF02458.10 GAO81781.1 - 7e-11 41.2 0.0 7.1e-10 37.9 0.0 2.0 1 1 0 1 1 1 1 Transferase family Trypsin PF00089.21 GAO81782.1 - 2.7e-08 33.6 0.2 2.7e-08 33.6 0.1 1.5 2 0 0 2 2 2 1 Trypsin Sugar_tr PF00083.19 GAO81783.1 - 0.01 14.4 2.1 0.016 13.8 1.5 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Ribosomal_L2_C PF03947.13 GAO81783.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain MFS_1 PF07690.11 GAO81784.1 - 3.1e-17 62.3 60.1 1.2e-09 37.3 14.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Acetyltransf_3 PF13302.1 GAO81785.1 - 2.8e-12 46.9 0.0 8.2e-07 29.2 0.0 2.5 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain ABC_tran PF00005.22 GAO81786.1 - 1e-63 213.6 0.0 1.9e-32 112.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO81786.1 - 8.5e-62 209.0 38.6 3.9e-37 128.1 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO81786.1 - 6.6e-13 48.4 4.0 5.1e-06 25.8 0.0 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO81786.1 - 9.1e-10 38.9 0.2 0.015 15.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAO81786.1 - 1.1e-08 34.4 0.2 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 GAO81786.1 - 5.6e-08 32.6 1.4 0.00056 19.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAO81786.1 - 4.2e-07 30.1 2.4 0.0053 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 GAO81786.1 - 9.9e-07 29.6 0.0 0.051 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO81786.1 - 3.8e-06 26.1 0.0 0.0096 15.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO81786.1 - 4.7e-06 26.1 1.3 0.083 12.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 GAO81786.1 - 5.3e-06 26.6 1.3 0.26 11.4 0.1 4.1 2 2 1 3 3 3 2 AAA domain APS_kinase PF01583.15 GAO81786.1 - 4.9e-05 23.0 0.3 0.071 12.7 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase Zeta_toxin PF06414.7 GAO81786.1 - 8.5e-05 21.7 0.1 0.38 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 GAO81786.1 - 0.00012 21.9 0.3 0.11 12.2 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 GAO81786.1 - 0.00019 21.2 0.4 1 9.3 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAO81786.1 - 0.00021 21.2 0.1 0.61 9.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 GAO81786.1 - 0.00023 21.5 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO81786.1 - 0.00036 20.8 0.0 0.96 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 GAO81786.1 - 0.0007 19.1 0.2 0.46 9.9 0.0 3.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 GAO81786.1 - 0.0019 16.8 0.9 0.04 12.4 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 GAO81786.1 - 0.0022 17.4 0.7 0.96 8.8 0.1 3.0 4 0 0 4 4 3 1 AAA-like domain AAA_5 PF07728.9 GAO81786.1 - 0.0067 16.1 0.1 3.2 7.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 GAO81786.1 - 0.0083 16.0 0.0 4.6 7.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 GAO81786.1 - 0.024 14.3 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAO81786.1 - 0.063 13.4 0.9 16 5.6 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.1 GAO81786.1 - 0.076 11.5 0.0 7.7 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_15 PF13175.1 GAO81786.1 - 0.088 11.8 0.0 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 GAO81786.1 - 0.13 11.8 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 GAO81786.1 - 0.18 10.6 0.0 14 4.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Peptidase_M10 PF00413.19 GAO81788.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 GAO81788.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAO81788.1 - 0.02 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAO81788.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 GAO81788.1 - 0.042 14.3 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 GAO81788.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.6 GAO81788.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M43 PF05572.8 GAO81788.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_S28 PF05577.7 GAO81789.1 - 0.042 12.4 0.3 0.066 11.7 0.2 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Reprolysin_4 PF13583.1 GAO81790.1 - 7.5e-07 28.8 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAO81790.1 - 8.6e-07 29.1 0.0 1.8e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAO81790.1 - 0.00041 20.3 0.0 0.00074 19.5 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 GAO81790.1 - 0.00054 19.7 0.2 0.0021 17.8 0.1 2.2 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 GAO81790.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Astacin PF01400.19 GAO81790.1 - 0.0053 16.1 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M64 PF09471.5 GAO81790.1 - 0.0065 16.1 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 IgA Peptidase M64 Peptidase_M57 PF12388.3 GAO81790.1 - 0.0096 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 GAO81790.1 - 0.017 14.0 0.1 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 GAO81790.1 - 0.03 14.8 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NAD_binding_8 PF13450.1 GAO81791.1 - 8.1e-12 45.0 0.1 2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO81791.1 - 1.5e-07 30.6 0.3 0.00018 20.4 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 GAO81791.1 - 3.2e-06 26.4 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 GAO81791.1 - 2.9e-05 23.3 0.0 6.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO81791.1 - 0.00022 21.1 0.0 0.0051 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO81791.1 - 0.00032 19.3 0.0 0.0007 18.1 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 GAO81791.1 - 0.00057 18.8 0.0 0.0034 16.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO81791.1 - 0.0008 19.5 0.0 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO81791.1 - 0.0052 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO81791.1 - 0.058 12.4 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAO81791.1 - 0.066 12.9 0.3 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 GAO81791.1 - 0.071 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAO81791.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO81791.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Nitroreductase PF00881.19 GAO81792.1 - 4.9e-05 23.1 0.0 0.00022 21.0 0.0 1.8 1 1 0 1 1 1 1 Nitroreductase family KR PF08659.5 GAO81793.1 - 3.8e-13 49.4 0.9 5.5e-09 35.9 0.1 3.0 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 GAO81793.1 - 9.7e-05 22.3 3.2 0.026 14.4 0.2 3.1 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_23 PF13489.1 GAO81793.1 - 0.0022 17.7 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAO81793.1 - 0.012 15.8 0.1 0.034 14.4 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Fungal_trans PF04082.13 GAO81794.1 - 7e-14 51.3 3.1 8.7e-14 51.0 1.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.8 GAO81795.1 - 5.7e-20 71.5 0.1 1.6e-19 70.1 0.0 1.7 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81795.1 - 2e-14 54.0 0.2 3.4e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO81795.1 - 2.4e-05 23.8 0.1 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO81795.1 - 0.00023 19.9 0.0 0.00037 19.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAO81795.1 - 0.00077 19.7 0.1 0.0016 18.6 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO81795.1 - 0.00079 19.3 0.4 0.0021 17.9 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAO81795.1 - 0.028 13.3 0.2 0.05 12.5 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein ApbA PF02558.11 GAO81795.1 - 0.03 13.7 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 GAO81795.1 - 0.037 14.5 0.2 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.18 GAO81795.1 - 0.075 12.8 0.7 0.19 11.5 0.5 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAO81795.1 - 0.098 11.5 0.2 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_5 PF07994.7 GAO81795.1 - 0.098 12.1 0.3 0.17 11.3 0.1 1.5 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase TrkA_N PF02254.13 GAO81795.1 - 0.11 12.4 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.11 GAO81796.1 - 9.9e-50 169.2 81.8 1.4e-40 139.1 39.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CHASE2 PF05226.6 GAO81796.1 - 0.0019 17.4 0.5 0.003 16.8 0.4 1.3 1 0 0 1 1 1 1 CHASE2 domain Zn_clus PF00172.13 GAO81797.1 - 4.1e-10 39.3 8.0 7.3e-10 38.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO81797.1 - 8.7e-06 24.7 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pack_C PF02499.10 GAO81797.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus His_Phos_1 PF00300.17 GAO81798.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.7 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 GAO81799.1 - 1.1e-30 106.5 69.6 3.4e-30 104.9 44.4 3.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 GAO81800.1 - 8.4e-33 113.4 4.7 3.7e-32 111.3 3.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.16 GAO81800.1 - 3.6e-29 101.6 0.1 5.7e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAA_hydrolase PF01557.13 GAO81800.1 - 3.9e-18 65.7 0.0 2.7e-09 36.8 0.0 2.4 1 1 1 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family DLH PF01738.13 GAO81801.1 - 6e-32 110.6 0.1 6.8e-32 110.5 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO81801.1 - 4e-07 29.8 0.1 5.9e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81801.1 - 0.0039 17.0 0.2 0.012 15.5 0.1 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO81801.1 - 0.043 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Rbsn PF11464.3 GAO81801.1 - 0.091 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain BsuPI PF12690.2 GAO81801.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Intracellular proteinase inhibitor Fungal_trans PF04082.13 GAO81802.1 - 8.4e-13 47.7 2.2 1.5e-12 46.9 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81802.1 - 2.1e-07 30.7 9.9 4.1e-07 29.8 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.16 GAO81803.1 - 8.8e-24 84.1 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAO81803.1 - 7e-13 48.5 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAO81803.1 - 1e-06 28.7 0.0 0.0014 18.5 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain DUF1772 PF08592.6 GAO81804.1 - 4.2e-13 49.2 1.8 5.6e-13 48.8 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Orai-1 PF07856.7 GAO81804.1 - 0.049 13.2 0.8 0.066 12.7 0.6 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity FTP PF07504.8 GAO81805.1 - 0.00061 19.2 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif CARDB PF07705.6 GAO81805.1 - 0.012 15.5 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 CARDB zf-C2H2 PF00096.21 GAO81806.1 - 1.6e-09 37.5 9.9 0.00023 21.3 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO81806.1 - 5.1e-06 26.4 9.2 0.0063 16.7 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO81806.1 - 2.6e-05 24.2 3.9 2.6e-05 24.2 2.7 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.7 GAO81806.1 - 0.0042 17.1 1.4 0.013 15.5 0.9 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 GAO81806.1 - 0.0074 16.1 4.3 0.1 12.5 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-XS PF03470.9 GAO81806.1 - 0.19 11.7 1.3 0.97 9.5 0.0 2.7 3 0 0 3 3 3 0 XS zinc finger domain zf-C2H2_2 PF12756.2 GAO81806.1 - 0.33 11.0 1.9 4.1 7.5 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 GAO81806.1 - 0.49 10.7 5.6 0.12 12.6 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FAD_binding_3 PF01494.14 GAO81807.1 - 9.3e-50 169.6 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO81807.1 - 7e-06 25.1 0.3 8.5e-05 21.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO81807.1 - 0.00012 21.2 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAO81807.1 - 0.00012 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO81807.1 - 0.00023 21.5 0.0 0.0035 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO81807.1 - 0.00083 17.9 0.0 0.0022 16.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAO81807.1 - 0.0046 16.8 0.1 0.0086 15.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO81807.1 - 0.0058 15.5 0.1 0.019 13.9 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO81807.1 - 0.0094 14.8 0.2 0.036 12.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAO81807.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAO81807.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3525 PF12039.3 GAO81808.1 - 0.049 12.1 0.0 0.072 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DLH PF01738.13 GAO81809.1 - 6.8e-30 103.9 0.0 8e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO81809.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81809.1 - 0.00032 20.6 0.0 0.024 14.5 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO81809.1 - 0.018 14.2 0.0 0.045 12.9 0.0 1.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 GAO81810.1 - 2.2e-38 131.6 0.2 3.5e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81810.1 - 2.9e-08 33.4 13.2 5.8e-08 32.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dispanin PF04505.7 GAO81810.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein NMT1 PF09084.6 GAO81811.1 - 8.7e-05 22.2 0.0 0.001 18.6 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.2 GAO81811.1 - 0.0017 17.8 0.0 0.0037 16.6 0.0 1.6 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 GAO81811.1 - 0.017 14.3 0.0 0.07 12.3 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 p450 PF00067.17 GAO81812.1 - 1.5e-31 109.4 0.0 2.8e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ADH_N PF08240.7 GAO81813.1 - 1.9e-10 40.4 0.0 3.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81813.1 - 1.6e-08 34.1 0.0 4.7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81813.1 - 3.4e-05 24.7 0.0 8.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF320 PF03777.8 GAO81813.1 - 0.11 12.2 0.5 0.28 10.9 0.4 1.7 1 0 0 1 1 1 0 Small secreted domain (DUF320) Glyco_hydro_2_N PF02837.13 GAO81814.1 - 3.1e-10 39.8 0.2 7.4e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAO81814.1 - 3e-06 27.6 0.5 2.1e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAO81814.1 - 3.5e-06 26.1 0.1 6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4243 PF14027.1 GAO81816.1 - 1.5e-67 228.4 0.6 1.7e-67 228.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 GAO81817.1 - 1.1e-10 41.8 0.0 1.4e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81817.1 - 2e-06 27.2 0.0 2.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAO81817.1 - 0.0027 17.1 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAO81817.1 - 0.044 14.0 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SBP_bac_3 PF00497.15 GAO81818.1 - 0.0013 17.9 0.1 0.17 11.1 0.0 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Abhydrolase_5 PF12695.2 GAO81820.1 - 7.7e-16 58.1 0.1 1.2e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81820.1 - 2e-06 27.2 0.4 6.7e-06 25.5 0.1 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 GAO81820.1 - 0.047 13.5 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative lysophospholipase BAAT_C PF08840.6 GAO81820.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Met_asp_mut_E PF06368.6 GAO81823.1 - 0.12 10.5 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Orexin_rec2 PF03827.8 GAO81823.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Orexin receptor type 2 FAD_binding_3 PF01494.14 GAO81824.1 - 1.2e-16 60.7 0.2 2.4e-09 36.7 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO81824.1 - 3.4e-05 23.7 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO81824.1 - 0.001 19.1 0.1 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO81824.1 - 0.0023 16.8 0.0 0.011 14.6 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.12 GAO81824.1 - 0.0061 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAO81824.1 - 0.0061 16.3 0.0 0.017 14.8 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 GAO81824.1 - 0.068 12.0 0.3 0.4 9.5 0.1 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 GAO81825.1 - 7.7e-16 57.7 1.1 1.8e-15 56.5 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAO81826.1 - 1.9e-17 63.0 0.3 3.9e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81826.1 - 2.2e-08 33.8 7.2 3.7e-08 33.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.7 GAO81826.1 - 0.044 13.7 0.3 0.23 11.4 0.0 2.3 3 0 0 3 3 3 0 Phage shock protein B adh_short PF00106.20 GAO81827.1 - 1.6e-14 54.1 0.0 2.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAO81827.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAO81827.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 KR domain AIRC PF00731.15 GAO81827.1 - 0.076 12.2 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 AIR carboxylase Glyco_hyd_65N_2 PF14498.1 GAO81828.1 - 0.046 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain HET PF06985.6 GAO81829.1 - 1.2e-17 64.3 0.1 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_5 PF12695.2 GAO81830.1 - 2e-10 40.5 0.0 2.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO81830.1 - 8.8e-09 35.5 0.1 1.3e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81830.1 - 5.7e-06 25.7 0.0 1.3e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 GAO81830.1 - 0.00074 19.0 0.0 0.00088 18.7 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 GAO81830.1 - 0.016 15.0 0.0 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase AXE1 PF05448.7 GAO81830.1 - 0.16 10.4 0.1 0.31 9.4 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 GAO81831.1 - 5.8e-13 48.3 0.0 1.7e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_tran_WecB PF03808.8 GAO81832.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_4 PF07993.7 GAO81832.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAO81832.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81832.1 - 0.036 14.0 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 GAO81832.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fringe PF02434.11 GAO81833.1 - 1.7e-07 30.7 0.0 1.1e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 GAO81833.1 - 0.00014 21.4 0.2 0.00028 20.5 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 GAO81833.1 - 0.00016 21.3 2.3 0.00049 19.7 1.6 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 GAO81833.1 - 0.017 14.9 0.7 0.04 13.7 0.5 1.5 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.16 GAO81833.1 - 0.026 14.0 0.1 0.64 9.5 0.0 2.2 1 1 1 2 2 2 0 Galactosyltransferase Pectinesterase PF01095.14 GAO81834.1 - 2.5e-28 98.5 0.2 1.5e-22 79.5 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase Sugar_tr PF00083.19 GAO81835.1 - 1.4e-78 264.4 17.0 1.7e-78 264.2 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81835.1 - 7.4e-17 61.0 25.7 1.4e-14 53.5 14.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO81836.1 - 0.00028 19.8 0.1 0.00061 18.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.18 GAO81837.1 - 7.5e-66 222.5 4.4 8.9e-66 222.2 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO81837.1 - 2.6e-10 40.5 0.0 1.1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAO81837.1 - 3.7e-05 24.1 1.0 0.021 15.2 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 GAO81837.1 - 9e-05 22.2 0.1 0.04 13.7 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 GAO81837.1 - 0.0057 16.2 0.2 0.055 13.0 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 GAO81837.1 - 0.021 14.7 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Mucin PF01456.12 GAO81838.1 - 2.7 7.7 9.2 3.2 7.5 6.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MLTD_N PF06474.7 GAO81838.1 - 5.9 7.1 5.4 19 5.5 0.2 2.7 2 1 0 2 2 2 0 MltD lipid attachment motif Ribosomal_L2 PF00181.18 GAO81839.1 - 0.095 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain HMG_CoA_synt_C PF08540.5 GAO81841.1 - 4.9e-96 321.5 0.4 6e-96 321.2 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 GAO81841.1 - 4.3e-86 286.8 0.0 6.3e-86 286.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3330 PF11809.3 GAO81841.1 - 0.018 14.9 0.1 0.062 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) Aa_trans PF01490.13 GAO81842.1 - 4.2e-54 183.5 34.1 4.8e-54 183.3 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SNARE_assoc PF09335.6 GAO81843.1 - 0.051 13.7 1.1 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 SNARE associated Golgi protein Romo1 PF10247.4 GAO81843.1 - 0.06 13.5 0.3 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ATPase_gene1 PF09527.5 GAO81843.1 - 0.093 12.5 0.3 0.093 12.5 0.2 2.1 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Fungal_trans PF04082.13 GAO81844.1 - 1e-10 40.9 0.0 1.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4177 PF13783.1 GAO81845.1 - 0.0027 17.2 0.2 2.6 7.7 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4177) Glyoxalase_4 PF13669.1 GAO81845.1 - 0.0083 16.1 0.1 1.2 9.2 0.0 3.3 3 1 1 4 4 4 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.20 GAO81846.1 - 1.3e-23 83.5 0.0 2.8e-23 82.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO81846.1 - 1.5e-05 24.1 0.5 0.3 10.1 0.1 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 GAO81846.1 - 0.0034 17.1 1.5 0.017 14.8 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO81846.1 - 0.0093 14.9 0.2 0.35 9.7 0.1 2.4 3 0 0 3 3 3 1 Kinase-like DUF3950 PF13132.1 GAO81847.1 - 0.27 10.7 0.1 0.27 10.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) FMN_red PF03358.10 GAO81848.1 - 2.3e-25 88.8 0.0 3.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Aconitase PF00330.15 GAO81849.1 - 8.3e-61 205.8 0.0 7.9e-41 140.0 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAO81849.1 - 2.8e-18 66.2 0.0 5.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain AhpC-TSA PF00578.16 GAO81850.1 - 2.3e-33 114.5 0.0 3.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 GAO81850.1 - 6.4e-14 51.3 0.4 1.1e-13 50.6 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 GAO81850.1 - 2.9e-12 46.3 0.0 3.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Glyco_hydro_30 PF02055.11 GAO81851.1 - 1.8e-45 155.1 3.6 2.3e-45 154.7 2.5 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 tRNA-synt_2c PF01411.14 GAO81852.1 - 7.3e-08 31.1 0.1 9.8e-08 30.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAO81852.1 - 1.6e-05 24.6 0.4 3e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SH3_3 PF08239.6 GAO81853.1 - 3.8e-07 30.1 0.1 7.8e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain GPI-anchored PF10342.4 GAO81854.1 - 2.2e-19 69.6 4.0 2.2e-19 69.6 2.7 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2808 PF10989.3 GAO81854.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Peptidase_M36 PF02128.10 GAO81855.1 - 9.2e-165 548.0 4.9 1.2e-164 547.6 3.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 GAO81855.1 - 1.9e-15 56.0 3.8 2.2e-14 52.6 3.2 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 GAO81855.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain SnoaL_2 PF12680.2 GAO81855.1 - 0.027 14.8 0.8 0.21 12.0 0.0 2.6 3 0 0 3 3 3 0 SnoaL-like domain Peptidase_MA_2 PF13485.1 GAO81855.1 - 0.031 14.3 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Dioxygenase_C PF00775.16 GAO81856.1 - 2.6e-09 36.6 0.0 5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Fungal_trans PF04082.13 GAO81857.1 - 2e-15 56.3 0.4 3.4e-15 55.6 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 GAO81858.1 - 8.8e-66 221.6 0.0 1.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 GAO81858.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Alpha-amylase PF00128.19 GAO81859.1 - 7.5e-95 317.9 0.2 1.4e-94 317.0 0.1 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAO81859.1 - 0.0068 15.3 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Hydrophobin PF01185.13 GAO81860.1 - 5.3e-12 46.0 7.1 6.7e-12 45.6 4.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin NAD_binding_10 PF13460.1 GAO81861.1 - 1.3e-05 25.3 0.0 2.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_3 PF01494.14 GAO81862.1 - 1.8e-19 70.0 0.1 5.5e-19 68.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 GAO81862.1 - 5.6e-16 58.1 0.0 8.9e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 GAO81862.1 - 2.4e-07 30.0 1.7 0.0014 17.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAO81862.1 - 3.1e-05 23.2 0.1 0.0029 16.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAO81862.1 - 0.00018 21.4 0.5 0.051 13.4 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO81862.1 - 0.0011 18.9 0.4 0.0027 17.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO81862.1 - 0.0012 17.7 0.7 0.0026 16.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAO81862.1 - 0.0022 16.9 0.6 0.077 11.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 GAO81862.1 - 0.0034 16.2 0.0 1.9 7.2 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.1 GAO81862.1 - 0.015 15.3 0.9 0.2 11.6 0.6 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO81862.1 - 0.031 13.1 1.3 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 GAO81862.1 - 0.24 10.4 0.3 0.56 9.2 0.2 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAO81862.1 - 0.25 11.0 2.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAO81862.1 - 0.3 9.6 0.9 28 3.1 0.1 3.0 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 GAO81862.1 - 0.46 8.8 1.3 1.6 7.0 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_25 PF01183.15 GAO81863.1 - 1.1e-44 152.4 2.3 1.3e-44 152.2 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Zn_clus PF00172.13 GAO81865.1 - 2.5e-05 24.0 12.5 6.1e-05 22.8 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO81865.1 - 0.025 13.2 0.0 0.056 12.0 0.0 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain TPR_12 PF13424.1 GAO81865.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO81865.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 GAO81867.1 - 3.8e-79 266.6 4.7 9.5e-79 265.3 3.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAO81867.1 - 1.7e-08 34.2 8.1 1.7e-08 34.2 5.6 5.7 7 0 0 7 7 7 2 Chitin recognition protein LysM PF01476.15 GAO81868.1 - 4.9e-35 119.1 2.6 1.2e-10 41.0 0.0 4.5 4 0 0 4 4 4 4 LysM domain Glyco_hydro_1 PF00232.13 GAO81869.1 - 2.9e-77 259.8 0.2 4.3e-75 252.6 0.2 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 MGC-24 PF05283.6 GAO81869.1 - 1.1 9.0 4.8 2.1 8.1 3.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_6 PF12697.2 GAO81870.1 - 7e-15 55.5 0.0 1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO81870.1 - 3.1e-14 52.9 0.0 7.2e-14 51.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81870.1 - 4.4e-10 39.4 0.2 5.6e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO81870.1 - 7.4e-10 38.4 0.0 0.00016 20.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 GAO81870.1 - 1.2e-08 34.5 0.0 5.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 GAO81870.1 - 5.7e-07 29.3 0.2 4.7e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAO81870.1 - 1.2e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.6 GAO81870.1 - 3e-05 23.8 0.0 7.1e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 GAO81870.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 GAO81870.1 - 0.0025 17.2 0.0 0.019 14.3 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAO81870.1 - 0.0044 15.5 0.0 0.014 13.9 0.0 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 GAO81870.1 - 0.0048 16.3 0.0 0.03 13.7 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAO81870.1 - 0.0051 16.4 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Albumin_I PF08027.6 GAO81870.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Albumin I Ser_hydrolase PF06821.8 GAO81870.1 - 0.0098 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 GAO81870.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF676 PF05057.9 GAO81870.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MoCF_biosynth PF00994.19 GAO81870.1 - 0.032 13.6 0.0 0.092 12.1 0.0 1.7 2 0 0 2 2 2 0 Probable molybdopterin binding domain DUF1100 PF06500.6 GAO81870.1 - 0.066 11.7 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 GAO81870.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Fungal_trans PF04082.13 GAO81872.1 - 1.4e-19 70.0 0.6 2.6e-19 69.1 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81872.1 - 3.3e-08 33.2 8.7 6e-08 32.4 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.8 GAO81872.1 - 0.03 14.0 2.7 0.063 13.0 1.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Na_H_Exchanger PF00999.16 GAO81873.1 - 1.7e-59 201.3 52.5 3.5e-58 196.9 36.4 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.21 GAO81873.1 - 0.00055 20.1 0.1 0.24 11.5 0.0 2.9 2 1 0 2 2 2 2 Universal stress protein family HA2 PF04408.18 GAO81873.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Helicase associated domain (HA2) MFS_1 PF07690.11 GAO81874.1 - 8.1e-32 110.2 37.8 1.1e-30 106.5 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.12 GAO81875.1 - 2.9e-49 167.7 13.1 3.7e-49 167.4 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 GAO81876.1 - 1.3e-54 184.7 6.8 1.7e-54 184.4 4.7 1.1 1 0 0 1 1 1 1 Pectinesterase Ank_2 PF12796.2 GAO81877.1 - 6.4e-16 58.4 0.0 1.2e-08 35.1 0.1 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81877.1 - 1.1e-12 47.0 0.1 0.00013 21.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAO81877.1 - 1.2e-10 41.5 0.1 0.00017 21.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81877.1 - 1.3e-08 34.8 0.2 0.00019 21.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81877.1 - 0.0013 18.7 0.0 3.8 8.0 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Sugar_tr PF00083.19 GAO81879.1 - 9.5e-89 298.0 22.5 1.2e-88 297.7 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO81879.1 - 1.3e-18 66.8 50.1 2.3e-17 62.7 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 GAO81879.1 - 0.51 9.6 5.5 1 8.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Zn_clus PF00172.13 GAO81880.1 - 2.5e-06 27.2 10.8 2.5e-06 27.2 7.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1688 PF07958.6 GAO81883.1 - 3.1e-170 566.2 0.0 3.5e-170 566.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) adh_short_C2 PF13561.1 GAO81884.1 - 1.5e-19 70.7 0.0 1.9e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81884.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81884.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain Kelch_4 PF13418.1 GAO81884.1 - 0.041 13.6 0.2 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain NAD_binding_10 PF13460.1 GAO81884.1 - 0.041 13.8 0.1 0.1 12.5 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding NSP2-B_epitope PF14757.1 GAO81885.1 - 0.13 11.6 3.1 0.15 11.5 2.2 1.0 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein LZ_Tnp_IS66 PF13007.2 GAO81885.1 - 0.24 12.0 3.3 0.18 12.4 1.3 1.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Glyco_hydro_61 PF03443.9 GAO81887.1 - 1.1e-65 221.4 0.5 1.7e-65 220.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAO81887.1 - 7.5e-11 41.4 8.5 7.5e-11 41.4 5.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DNA_pol_A_exo1 PF01612.15 GAO81888.1 - 3.6e-06 26.5 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Abhydrolase_3 PF07859.8 GAO81889.1 - 7.3e-21 74.7 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81889.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO81889.1 - 1.7e-07 30.7 0.0 0.0009 18.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 GAO81889.1 - 1.4e-06 27.0 0.0 0.014 13.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.23 GAO81889.1 - 6.1e-06 25.2 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAO81889.1 - 9.1e-06 25.7 1.0 1.3e-05 25.1 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO81889.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_42M PF08532.5 GAO81889.1 - 0.024 13.8 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain MFS_1 PF07690.11 GAO81891.1 - 1.8e-36 125.6 60.8 1.9e-32 112.3 31.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 GAO81891.1 - 5.4e-05 21.9 0.0 5.4e-05 21.9 0.0 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter Glyco_transf_28 PF03033.15 GAO81892.1 - 5.2e-22 78.0 0.1 3.1e-21 75.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAO81892.1 - 1.1e-06 27.4 0.0 1.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 GAO81892.1 - 0.0034 17.4 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 GAO81892.1 - 0.014 15.0 0.2 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PI3K_1B_p101 PF10486.4 GAO81892.1 - 1.9 5.9 5.1 3.8 4.9 3.5 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.6 GAO81892.1 - 2.4 5.9 10.8 2.4 5.9 4.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Glyco_hydro_28 PF00295.12 GAO81893.1 - 1.2e-95 320.2 16.7 1.8e-95 319.6 11.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAO81893.1 - 1e-05 25.3 43.0 0.00027 20.7 17.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region Annexin PF00191.15 GAO81894.1 - 1.5e-55 184.9 0.9 1e-20 73.3 0.0 3.8 4 0 0 4 4 4 3 Annexin Ank_2 PF12796.2 GAO81896.1 - 9.4e-27 93.1 0.0 7.9e-15 54.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81896.1 - 1.3e-25 87.8 2.2 4e-08 32.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAO81896.1 - 1.6e-22 79.4 0.4 2.9e-12 46.7 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81896.1 - 1.1e-17 62.2 0.8 0.00027 20.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 GAO81896.1 - 3.2e-16 58.9 0.6 6e-10 39.0 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) ABC_tran PF00005.22 GAO81897.1 - 2.4e-22 79.6 0.0 6.2e-20 71.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 GAO81897.1 - 8.1e-19 68.0 14.1 1.4e-13 50.9 7.6 2.3 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO81897.1 - 1.9e-07 30.5 0.0 8.7e-05 21.8 0.0 2.8 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO81897.1 - 7.8e-07 29.3 0.1 0.0001 22.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO81897.1 - 0.0013 18.8 0.0 0.018 15.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO81897.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 GAO81897.1 - 0.003 17.0 0.1 0.012 15.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 GAO81897.1 - 0.0055 15.6 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 GAO81897.1 - 0.01 15.2 0.1 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 GAO81897.1 - 0.023 13.2 0.2 0.15 10.6 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 GAO81897.1 - 0.024 14.3 0.0 0.062 13.0 0.0 1.7 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.1 GAO81897.1 - 0.03 14.2 3.9 4.2 7.3 0.0 3.5 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAO81897.1 - 0.063 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 GAO81897.1 - 0.063 12.9 0.4 0.51 10.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAO81897.1 - 0.088 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 GAO81897.1 - 0.091 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 GAO81897.1 - 0.1 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAO81897.1 - 0.14 11.8 0.1 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DAP3 PF10236.4 GAO81897.1 - 0.18 10.7 0.9 1 8.1 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PMM PF03332.8 GAO81898.1 - 1.8e-75 253.2 0.0 2e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF1932 PF09130.6 GAO81898.1 - 0.091 12.5 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) COesterase PF00135.23 GAO81900.1 - 2.4e-90 303.7 0.0 3.7e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family GalP_UDP_transf PF01087.17 GAO81900.1 - 2.6e-49 167.7 0.0 4.4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 GAO81900.1 - 6e-37 126.7 0.0 1.1e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 GAO81900.1 - 0.012 16.1 0.0 0.034 14.6 0.0 1.8 2 0 0 2 2 2 0 HIT domain Abhydrolase_3 PF07859.8 GAO81900.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_9 PF13527.1 GAO81900.1 - 0.08 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_25 PF01755.12 GAO81902.1 - 8.6e-07 28.8 0.3 1.1e-05 25.2 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short PF00106.20 GAO81903.1 - 2.5e-15 56.7 0.2 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO81903.1 - 2e-10 40.6 0.0 1.2e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAO81903.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAO81903.1 - 0.0057 16.7 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAO81903.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAO81903.1 - 0.015 14.7 0.0 1.3 8.3 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ADH_N PF08240.7 GAO81904.1 - 6.2e-12 45.2 0.0 1.7e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO81904.1 - 1.2e-09 39.1 0.1 2.9e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO81904.1 - 9.4e-06 25.2 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Collar PF07484.7 GAO81905.1 - 3.1e-39 132.5 4.3 5.6e-15 54.8 0.1 4.4 4 0 0 4 4 4 3 Phage Tail Collar Domain Bac_rhamnosid PF05592.6 GAO81906.1 - 4.4e-29 101.0 0.0 1.1e-23 83.2 0.1 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Laminin_G_2 PF02210.19 GAO81906.1 - 0.025 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Laminin_G_1 PF00054.18 GAO81906.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain FAA_hydrolase PF01557.13 GAO81907.1 - 4.2e-55 186.5 0.0 6e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ATP_transf PF09830.4 GAO81908.1 - 2.3e-16 59.3 0.0 4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase FAD_binding_3 PF01494.14 GAO81909.1 - 1.8e-40 139.1 0.0 2.1e-24 86.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAO81909.1 - 9.3e-06 24.8 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAO81909.1 - 1.7e-05 23.8 0.0 0.00014 20.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO81909.1 - 0.00016 20.6 0.1 0.00033 19.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO81909.1 - 0.00023 21.0 0.1 0.00065 19.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO81909.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO81909.1 - 0.0067 15.3 0.4 0.069 12.0 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein CCDC71L PF15374.1 GAO81909.1 - 0.0068 15.7 0.1 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L HI0933_like PF03486.9 GAO81909.1 - 0.012 14.1 0.0 0.017 13.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAO81909.1 - 0.045 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO81909.1 - 0.13 12.0 0.2 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO81909.1 - 0.14 12.6 0.1 0.14 12.6 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyoxalase PF00903.20 GAO81910.1 - 1.8e-11 44.1 1.3 8.1e-11 42.0 0.9 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO81910.1 - 1.1e-07 32.3 0.9 0.0044 17.5 0.1 3.0 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAO81910.1 - 0.0078 16.2 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NmrA PF05368.8 GAO81911.1 - 1.1e-60 204.8 0.0 1.2e-58 198.1 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAO81911.1 - 7.5e-19 68.2 0.2 2.5e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO81911.1 - 2.2e-15 57.1 0.0 4.3e-14 52.9 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 GAO81911.1 - 9e-13 48.5 0.0 1.8e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 GAO81911.1 - 8.5e-12 44.4 0.2 1.5e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 GAO81911.1 - 8.3e-06 24.6 0.0 1.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.13 GAO81911.1 - 0.0024 17.7 0.5 0.0043 16.9 0.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.5 GAO81911.1 - 0.05 12.7 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.13 GAO81913.1 - 1.3e-29 102.9 0.1 1.8e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.19 GAO81914.1 - 1.2e-11 44.2 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase ECH PF00378.15 GAO81915.1 - 8.3e-39 133.1 0.2 1.6e-38 132.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S26 PF10502.4 GAO81916.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 EthD PF07110.6 GAO81916.1 - 0.065 14.1 0.1 0.36 11.7 0.0 1.9 1 1 0 1 1 1 0 EthD domain ADH_zinc_N_2 PF13602.1 GAO81917.1 - 8.7e-10 39.5 0.0 1.8e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO81917.1 - 0.018 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81917.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 GAO81918.1 - 1.3e-18 67.2 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81918.1 - 9.1e-18 64.9 0.3 1.2e-17 64.5 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81918.1 - 1.9e-10 40.3 0.2 2.9e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 GAO81918.1 - 6.9e-10 38.2 0.0 1.1e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAO81918.1 - 1.5e-08 33.7 0.1 2e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAO81918.1 - 9.5e-07 28.8 0.1 1.6e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 GAO81918.1 - 5e-06 25.6 0.9 0.00016 20.7 0.2 2.5 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 GAO81918.1 - 7.5e-05 21.8 0.4 0.00011 21.2 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 GAO81918.1 - 0.0018 18.2 1.5 0.0056 16.6 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAO81918.1 - 0.0021 17.0 0.1 0.014 14.3 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 GAO81918.1 - 0.0068 16.3 0.3 0.04 13.8 0.1 2.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 GAO81918.1 - 0.008 16.5 0.1 0.025 14.9 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAO81918.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAO81918.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.10 GAO81918.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 GAO81918.1 - 0.059 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.21 GAO81918.1 - 0.064 12.7 1.0 0.14 11.6 0.7 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1440 PF07274.7 GAO81919.1 - 0.02 14.9 0.4 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) AA_permease_2 PF13520.1 GAO81920.1 - 2.2e-54 184.6 41.8 3e-54 184.1 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO81920.1 - 3.5e-23 81.6 36.2 4.8e-23 81.2 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease Esterase_phd PF10503.4 GAO81921.1 - 1.1e-24 86.8 0.6 1.7e-24 86.2 0.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 GAO81921.1 - 8.2e-15 54.1 13.3 4.6e-14 51.7 9.3 2.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 GAO81921.1 - 3.1e-10 39.6 2.4 4.9e-10 38.9 1.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO81921.1 - 4.8e-06 26.3 0.2 7.3e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO81921.1 - 0.0013 18.2 1.2 0.0021 17.5 0.8 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 GAO81921.1 - 0.0027 17.3 0.1 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO81921.1 - 0.0038 17.1 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Toxin_7 PF05980.7 GAO81921.1 - 0.0043 17.0 2.3 0.0043 17.0 1.6 2.0 2 0 0 2 2 2 1 Toxin 7 COesterase PF00135.23 GAO81921.1 - 0.0062 15.2 0.7 0.0062 15.2 0.5 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.15 GAO81921.1 - 0.025 14.1 0.1 0.044 13.3 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 GAO81921.1 - 0.08 12.6 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal hEGF PF12661.2 GAO81921.1 - 6.5 7.0 8.7 54 4.1 0.3 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF MFS_1 PF07690.11 GAO81922.1 - 2.2e-13 49.6 35.5 6.3e-13 48.1 24.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAO81922.1 - 1.3e-08 34.4 7.5 1.3e-08 34.4 5.2 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Pro_CA PF00484.14 GAO81923.1 - 7.1e-49 165.7 0.2 9.2e-49 165.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AMP-binding PF00501.23 GAO81924.1 - 1.5e-83 280.5 0.0 2.1e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO81924.1 - 9e-59 198.3 0.0 1.3e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAO81924.1 - 4.8e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAO81924.1 - 6.9e-10 38.0 0.0 1.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO81924.1 - 1.1e-09 38.0 0.0 3.4e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 GAO81924.1 - 1.1e-08 35.8 0.0 4.4e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 GAO81924.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lipase_GDSL_2 PF13472.1 GAO81929.1 - 5.4e-10 39.6 0.0 6.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DAO PF01266.19 GAO81930.1 - 5.4e-65 219.6 0.9 1e-64 218.6 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 GAO81930.1 - 3e-53 180.3 0.0 5.1e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAO81930.1 - 9.1e-16 57.6 0.1 2.4e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 GAO81930.1 - 3.7e-05 23.8 0.0 0.00019 21.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 GAO81930.1 - 0.00024 21.0 0.0 0.0029 17.4 0.0 2.5 2 1 0 2 2 2 1 Sarcosine oxidase, gamma subunit family NAD_binding_9 PF13454.1 GAO81930.1 - 0.0021 17.8 0.3 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 GAO81930.1 - 0.0059 16.6 0.1 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 GAO81930.1 - 0.0065 15.5 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain ThiF PF00899.16 GAO81930.1 - 0.0092 15.8 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 GAO81930.1 - 0.011 14.5 0.4 0.029 13.2 0.3 1.7 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAO81930.1 - 0.012 15.9 6.0 0.028 14.8 0.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO81930.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81930.1 - 0.024 14.6 0.0 0.094 12.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAO81930.1 - 0.03 12.9 1.6 0.19 10.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase IGFL PF14653.1 GAO81930.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Insulin growth factor-like family Fungal_trans PF04082.13 GAO81931.1 - 6.1e-10 38.4 0.3 1.1e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.14 GAO81932.1 - 4.5e-37 127.7 2.8 2.8e-36 125.1 1.9 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 GAO81932.1 - 3.1e-15 55.4 0.0 6.2e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 GAO81933.1 - 2.8e-52 177.8 0.0 3.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO81933.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO81933.1 - 3.5e-07 30.3 0.0 0.021 14.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO81933.1 - 2.3e-05 24.2 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO81933.1 - 0.00023 21.2 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO81933.1 - 0.00083 18.3 0.0 0.052 12.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAO81933.1 - 0.0022 18.3 0.0 0.076 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO81933.1 - 0.0023 16.6 0.0 0.088 11.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 GAO81933.1 - 0.0029 16.1 0.1 0.23 9.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 GAO81933.1 - 0.004 16.2 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 GAO81933.1 - 0.038 13.8 0.1 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.19 GAO81933.1 - 0.044 12.6 0.2 0.61 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAO81933.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DIOX_N PF14226.1 GAO81933.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Shikimate_DH PF01488.15 GAO81933.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3328 PF11807.3 GAO81935.1 - 6.6e-55 186.1 0.3 8.5e-55 185.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 GAO81936.1 - 4.2e-14 52.0 22.6 4.2e-14 52.0 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO81937.1 - 5.6e-68 229.5 16.9 1.3e-67 228.3 11.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter NmrA PF05368.8 GAO81937.1 - 7.9e-27 94.0 0.1 1.2e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.11 GAO81937.1 - 1.9e-17 63.0 41.6 1.4e-11 43.7 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 GAO81937.1 - 4e-10 39.9 0.0 6.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 GAO81937.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arteri_Gl PF00951.13 GAO81937.1 - 0.022 14.3 0.1 0.022 14.3 0.1 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Semialdhyde_dh PF01118.19 GAO81937.1 - 0.031 14.5 0.1 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAO81937.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 GAO81938.1 - 9e-36 122.0 0.6 6.2e-15 55.3 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO81938.1 - 4.2e-25 87.6 1.7 2.6e-07 30.9 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81938.1 - 5.7e-23 80.4 0.1 1.5e-11 44.1 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 GAO81938.1 - 2.7e-21 74.2 4.8 6.9e-06 25.6 0.0 6.4 6 1 0 6 6 6 4 Ankyrin repeat Pkinase PF00069.20 GAO81938.1 - 2.1e-19 69.7 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 GAO81938.1 - 4.1e-17 60.5 0.2 0.00045 20.1 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Pkinase_Tyr PF07714.12 GAO81938.1 - 1.7e-10 40.4 0.0 3.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2855 PF11017.3 GAO81939.1 - 1.5e-94 316.6 0.0 1.8e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Beta-lactamase PF00144.19 GAO81940.1 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase AA_permease_2 PF13520.1 GAO81941.1 - 9.6e-64 215.4 43.7 1.2e-63 215.0 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO81941.1 - 2.3e-26 92.1 34.5 3.2e-26 91.7 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease Amidohydro_4 PF13147.1 GAO81942.1 - 2.7e-31 109.6 10.1 2.4e-29 103.2 7.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAO81942.1 - 1e-12 48.3 1.3 9.1e-11 41.9 0.9 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAO81942.1 - 6.9e-09 35.4 0.4 2.4e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAO81942.1 - 7.5e-09 35.2 9.8 5.3e-07 29.2 3.4 2.9 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 GAO81943.1 - 1.1e-26 93.9 0.5 1.4e-26 93.6 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase GvpG PF05120.7 GAO81943.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G MFS_1 PF07690.11 GAO81945.1 - 5.3e-31 107.6 27.0 5.3e-31 107.6 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-C2H2 PF00096.21 GAO81945.1 - 2.6e-08 33.7 10.8 0.00028 21.0 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO81945.1 - 1.2e-06 28.4 3.0 1.2e-06 28.4 2.1 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO81945.1 - 1.9e-06 27.7 11.2 0.0034 17.6 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 GAO81945.1 - 0.0049 16.9 1.4 0.0049 16.9 1.0 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 GAO81945.1 - 0.053 13.7 4.2 0.12 12.6 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GerA PF03323.8 GAO81945.1 - 0.69 7.9 2.4 1.4 6.9 1.6 1.4 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein FAA_hydrolase PF01557.13 GAO81946.1 - 1.3e-56 191.4 0.0 1.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 GAO81947.1 - 2.8e-09 37.0 5.7 2.4e-08 34.0 1.6 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO81947.1 - 4.6e-09 36.8 1.0 0.0011 19.4 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain FAD_binding_3 PF01494.14 GAO81948.1 - 1.9e-34 119.2 0.0 1.8e-33 116.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAO81948.1 - 0.0097 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Glyco_hydro_71 PF03659.9 GAO81950.1 - 9.2e-157 521.4 3.8 9.2e-157 521.4 2.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Pyridoxal_deC PF00282.14 GAO81950.1 - 2e-74 250.2 0.0 2.7e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NAD_binding_10 PF13460.1 GAO81951.1 - 2.9e-11 43.7 0.0 4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO81951.1 - 2.6e-10 39.9 0.0 3.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF348 PF03990.9 GAO81951.1 - 0.0054 16.2 0.2 1.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF348) adh_short PF00106.20 GAO81951.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAO81951.1 - 0.049 13.0 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 GAO81951.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 GAO81952.1 - 3.2e-06 26.2 0.1 7.5e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4129 PF13559.1 GAO81952.1 - 0.049 13.6 0.3 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) ADH_zinc_N_2 PF13602.1 GAO81954.1 - 1.9e-13 51.4 0.0 3.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO81954.1 - 2.3e-12 46.5 0.0 4.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO81954.1 - 4.8e-06 26.2 0.6 5.1e-05 23.0 0.3 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAO81954.1 - 0.0011 18.9 0.1 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding HisG_C PF08029.6 GAO81954.1 - 0.11 12.4 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 HisG, C-terminal domain NmrA PF05368.8 GAO81955.1 - 2.3e-36 125.2 0.2 7e-36 123.6 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81955.1 - 3e-10 40.3 0.1 7.9e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 GAO81955.1 - 1.6e-05 24.8 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 GAO81955.1 - 0.00064 19.6 1.0 0.001 19.0 0.2 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO81955.1 - 0.0074 15.9 1.0 0.052 13.2 0.0 2.3 2 1 0 3 3 3 1 KR domain Semialdhyde_dh PF01118.19 GAO81955.1 - 0.045 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF4286 PF14114.1 GAO81955.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Epimerase PF01370.16 GAO81955.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4267 PF14087.1 GAO81956.1 - 1.4e-19 69.7 2.2 1.7e-19 69.4 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) YesK PF14150.1 GAO81956.1 - 0.12 12.4 1.5 3 8.0 0.0 2.2 2 0 0 2 2 2 0 YesK-like protein T5orf172 PF10544.4 GAO81957.1 - 1.5e-22 79.8 0.5 4.1e-22 78.4 0.4 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 GAO81957.1 - 4.3e-21 75.1 1.8 1.5e-20 73.4 1.2 2.0 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 A2L_zn_ribbon PF08792.5 GAO81957.1 - 0.11 11.9 0.1 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain RelA_SpoT PF04607.12 GAO81958.1 - 5.5e-16 58.6 0.1 1.2e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Amidohydro_2 PF04909.9 GAO81959.1 - 8.2e-35 120.6 0.1 9.4e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 GAO81960.1 - 3.3e-30 104.8 0.0 5e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81960.1 - 1.6e-06 27.9 9.2 1.6e-06 27.9 6.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 GAO81961.1 - 7.1e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IDO PF01231.13 GAO81962.1 - 1e-79 268.0 0.0 1.1e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AMP-binding PF00501.23 GAO81963.1 - 2e-64 217.5 0.0 2.7e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAO81963.1 - 1.2e-07 30.9 0.0 1.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 GAO81963.1 - 0.00058 20.0 0.2 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO81963.1 - 0.0063 17.4 0.2 0.029 15.3 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 GAO81964.1 - 4e-64 216.5 1.2 5e-64 216.2 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO81964.1 - 6.4e-61 206.4 0.0 1.1e-60 205.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAO81964.1 - 1.1e-55 188.1 0.0 3.2e-55 186.6 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAO81964.1 - 1.8e-55 188.2 0.0 3.1e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAO81964.1 - 1.7e-40 138.7 0.3 7.5e-40 136.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO81964.1 - 9.4e-34 115.8 0.2 2.6e-33 114.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO81964.1 - 1.1e-19 70.6 0.0 1.7e-18 66.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO81964.1 - 3.4e-18 65.4 0.0 1.8e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO81964.1 - 1.2e-14 55.2 0.0 7.8e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAO81964.1 - 7.4e-13 48.3 0.0 1.9e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO81964.1 - 8.3e-12 45.1 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO81964.1 - 1.3e-10 41.8 0.0 4.6e-10 40.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO81964.1 - 1.8e-08 34.7 0.0 4.5e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAO81964.1 - 1.3e-07 31.3 0.1 5.7e-07 29.2 0.1 2.2 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAO81964.1 - 1.4e-07 31.6 0.1 3.7e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO81964.1 - 0.0002 20.4 0.5 0.00041 19.4 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAO81964.1 - 0.00032 20.1 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 GAO81964.1 - 0.0011 18.1 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO81964.1 - 0.012 15.6 0.0 0.04 13.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 GAO81964.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 GAO81964.1 - 0.014 14.9 0.0 0.042 13.3 0.0 1.7 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ACP_syn_III PF08545.5 GAO81964.1 - 0.036 13.7 0.8 0.093 12.3 0.6 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RrnaAD PF00398.15 GAO81964.1 - 0.25 10.3 0.0 0.46 9.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1645 PF07816.6 GAO81964.1 - 0.47 10.8 0.0 0.88 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) WD40 PF00400.27 GAO81965.1 - 3.6e-21 74.1 12.3 2.7e-09 36.5 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Fungal_lectin PF07938.7 GAO81965.1 - 1.6e-16 60.4 4.5 3.3e-08 33.1 0.2 2.4 1 1 1 2 2 2 2 Fungal fucose-specific lectin DUF2424 PF10340.4 GAO81966.1 - 3.3e-21 75.3 0.0 2.8e-17 62.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 GAO81966.1 - 2.4e-17 63.2 0.0 4.8e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO81966.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO81966.1 - 0.00045 20.0 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAO81966.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 GAO81966.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AA_permease PF00324.16 GAO81967.1 - 5.3e-44 150.3 43.7 3.6e-42 144.3 30.3 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO81967.1 - 7.5e-21 74.1 34.9 1e-20 73.6 24.2 1.3 1 0 0 1 1 1 1 Amino acid permease PrkA PF06798.7 GAO81968.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain CorA PF01544.13 GAO81968.1 - 0.15 11.0 13.0 0.86 8.5 9.0 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 GAO81969.1 - 2.2e-25 89.3 0.0 3.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO81969.1 - 4e-19 68.6 0.0 7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 GAO81970.1 - 1.5e-30 103.9 0.7 1.8e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Robl_LC7 PF03259.12 GAO81970.1 - 0.044 13.3 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain TT_ORF2a PF08197.6 GAO81971.1 - 0.0041 16.8 0.1 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 pORF2a truncated protein adh_short PF00106.20 GAO81973.1 - 6.8e-24 84.6 0.0 8.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81973.1 - 4.3e-13 49.5 0.0 5.6e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO81973.1 - 8.1e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO81973.1 - 0.0006 19.5 0.3 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO81973.1 - 0.00083 18.8 0.1 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81973.1 - 0.0045 17.0 0.1 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO81973.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAO81973.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApoLp-III PF07464.6 GAO81973.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ThiF PF00899.16 GAO81973.1 - 1.1 9.1 3.0 3.4 7.4 0.0 2.4 1 1 1 2 2 2 0 ThiF family Fungal_trans_2 PF11951.3 GAO81974.1 - 2.8e-07 29.4 0.1 4.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vma12 PF11712.3 GAO81974.1 - 0.024 14.3 0.2 0.07 12.8 0.2 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2985 PF11204.3 GAO81975.1 - 6.4e-21 73.8 0.9 1.8e-20 72.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Epimerase PF01370.16 GAO81976.1 - 4.1e-15 55.8 0.0 1.5e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO81976.1 - 1e-11 45.1 0.1 3.5e-11 43.4 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO81976.1 - 5.5e-10 38.4 0.0 9.1e-10 37.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAO81976.1 - 7.9e-06 25.2 0.1 7.5e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAO81976.1 - 1.3e-05 25.2 0.4 3.7e-05 23.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO81976.1 - 0.00011 21.2 0.7 0.0014 17.6 0.3 2.3 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO81976.1 - 0.0031 16.4 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_N PF08240.7 GAO81978.1 - 1.1e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO81978.1 - 1.7e-08 34.0 0.3 3.3e-08 33.1 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_FMN PF00724.15 GAO81979.1 - 8.3e-44 149.9 0.0 1e-39 136.4 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family ABM PF03992.11 GAO81980.1 - 0.094 12.7 0.9 1.3 9.1 0.1 2.6 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase NmrA PF05368.8 GAO81981.1 - 1.7e-15 56.9 0.0 2.1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO81981.1 - 1.7e-11 44.4 0.0 3.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 GAO81981.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_6 PF12697.2 GAO81982.1 - 8.2e-23 81.4 0.0 1e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO81982.1 - 8.8e-16 58.1 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO81982.1 - 2.2e-09 37.2 0.0 3.5e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAO81982.1 - 0.016 14.5 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_hydro_3 PF00933.16 GAO81983.1 - 3.2e-49 167.5 0.0 4.4e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO81983.1 - 1.3e-39 136.0 0.0 3.8e-39 134.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_43 PF04616.9 GAO81984.1 - 7e-22 77.8 0.8 8.4e-22 77.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_14 PF01373.12 GAO81984.1 - 0.015 14.0 0.4 0.019 13.7 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 COesterase PF00135.23 GAO81985.1 - 2.3e-95 320.3 0.0 3.1e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO81985.1 - 0.00034 20.2 0.7 0.0022 17.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 GAO81986.1 - 5e-22 78.5 0.2 8.9e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO81986.1 - 1.1e-16 61.3 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 GAO81986.1 - 5.1e-11 41.9 0.1 8.3e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 GAO81986.1 - 2.1e-07 30.7 0.1 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Aminotran_3 PF00202.16 GAO81987.1 - 4.1e-38 131.0 0.1 8.6e-38 130.0 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.16 GAO81988.1 - 3.6e-81 272.6 0.0 4.3e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 GAO81989.1 - 2.3e-09 36.3 4.5 5.1e-09 35.1 3.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO81989.1 - 7.6e-06 25.7 8.2 1.4e-05 24.8 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 GAO81990.1 - 2.3e-27 95.1 3.9 3.8e-14 52.7 1.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81990.1 - 5e-26 89.1 5.7 6.7e-09 35.1 0.0 6.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAO81990.1 - 9e-25 86.5 5.5 1.2e-07 32.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO81990.1 - 2.3e-19 68.9 2.4 4.2e-10 39.5 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81990.1 - 1.2e-15 56.0 0.2 5.5e-05 23.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ribosomal_S6 PF01250.12 GAO81990.1 - 0.14 12.0 0.1 7.3 6.5 0.0 2.8 1 1 2 3 3 3 0 Ribosomal protein S6 Shigella_OspC PF06128.6 GAO81990.1 - 0.14 11.6 1.0 9.7 5.5 0.0 2.6 2 1 1 3 3 3 0 Shigella flexneri OspC protein MORN PF02493.15 GAO81991.1 - 1.6e-38 128.1 63.3 5.4e-07 28.9 1.8 9.6 10 0 0 10 10 10 9 MORN repeat NAP PF00956.13 GAO81992.1 - 4.8e-61 205.9 0.1 4.8e-61 205.9 0.1 3.0 2 1 1 3 3 3 1 Nucleosome assembly protein (NAP) DUF605 PF04652.11 GAO81992.1 - 3.8 6.8 15.5 5 6.4 10.8 1.3 1 0 0 1 1 1 0 Vta1 like Myosin_tail_1 PF01576.14 GAO81993.1 - 3.3e-05 21.8 1.8 4e-05 21.5 1.3 1.0 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 GAO81993.1 - 0.00019 21.1 0.2 0.00025 20.6 0.1 1.1 1 0 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 GAO81993.1 - 0.00046 20.0 7.9 0.0024 17.8 2.7 2.4 1 1 1 2 2 2 2 bZIP transcription factor Spc7 PF08317.6 GAO81993.1 - 0.0025 16.5 0.2 0.0035 16.0 0.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein MAD PF05557.8 GAO81993.1 - 0.0048 15.0 3.0 0.0062 14.6 2.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein ADIP PF11559.3 GAO81993.1 - 0.005 16.7 3.7 0.0093 15.8 2.6 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 GAO81993.1 - 0.009 15.5 2.8 0.017 14.6 2.0 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 GAO81993.1 - 0.0095 16.2 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 GAO81993.1 - 0.017 14.9 1.7 0.027 14.2 1.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain APG6 PF04111.7 GAO81993.1 - 0.022 13.8 1.1 0.029 13.4 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 GAO81993.1 - 0.025 14.4 8.1 0.049 13.4 5.6 1.4 1 0 0 1 1 1 0 Tropomyosin like CCDC155 PF14662.1 GAO81993.1 - 0.045 13.3 4.2 0.15 11.6 2.9 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 BLOC1_2 PF10046.4 GAO81993.1 - 0.064 13.3 1.7 0.16 12.1 1.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 GAO81993.1 - 0.072 13.3 9.8 0.38 11.0 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Lectin_N PF03954.9 GAO81993.1 - 0.12 11.7 0.7 0.18 11.2 0.5 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Shugoshin_N PF07558.6 GAO81993.1 - 0.12 12.0 1.6 0.29 10.8 1.1 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.7 GAO81993.1 - 0.24 11.1 6.9 0.4 10.4 4.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 GAO81993.1 - 0.25 11.1 6.0 3 7.7 3.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 GAO81993.1 - 0.26 11.2 3.2 4.3 7.3 0.1 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 GAO81993.1 - 0.37 10.6 11.4 0.63 9.8 7.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2353 PF09789.4 GAO81993.1 - 0.4 9.8 9.8 0.32 10.1 5.1 1.7 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 GAO81993.1 - 0.88 9.1 9.8 9.8 5.7 6.8 2.2 1 1 0 1 1 1 0 Septum formation initiator DUF3552 PF12072.3 GAO81993.1 - 0.88 8.7 7.9 1.3 8.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) adh_short_C2 PF13561.1 GAO81994.1 - 7.7e-31 107.6 0.1 9.4e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO81994.1 - 1.2e-29 103.3 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO81994.1 - 2e-11 43.8 0.1 3e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO81994.1 - 0.015 14.7 0.1 0.15 11.4 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO81994.1 - 0.036 13.8 0.6 0.085 12.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAO81994.1 - 0.047 12.7 0.1 0.13 11.3 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 GAO81994.1 - 0.067 13.0 1.3 0.16 11.7 0.5 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bacteriocin_IId PF09221.5 GAO81994.1 - 0.32 10.9 10.3 1.1 9.2 0.2 3.2 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like MBOAT_2 PF13813.1 GAO81996.1 - 2.3e-23 82.0 1.5 6.7e-23 80.5 1.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MARVEL PF01284.18 GAO81997.1 - 2.8e-15 56.4 17.2 4.1e-15 55.8 11.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain Renin_r PF07850.9 GAO81997.1 - 0.37 11.1 0.1 0.37 11.1 0.1 1.9 3 0 0 3 3 3 0 Renin receptor-like protein HemY_N PF07219.8 GAO81997.1 - 1.7 8.2 8.6 0.52 9.8 0.3 2.6 2 1 0 2 2 2 0 HemY protein N-terminus DUF202 PF02656.10 GAO81998.1 - 5.5e-18 64.9 3.8 5.5e-18 64.9 2.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ank_2 PF12796.2 GAO81999.1 - 3.7e-45 152.1 0.1 1.1e-11 44.9 0.2 5.9 7 0 0 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO81999.1 - 2.7e-41 137.3 6.8 7.7e-07 28.6 0.1 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAO81999.1 - 1.7e-32 111.2 1.6 3.8e-07 30.4 0.0 6.0 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO81999.1 - 9.2e-31 102.8 0.5 0.0001 22.1 0.0 8.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 GAO81999.1 - 6.5e-23 80.2 6.7 0.00022 21.3 0.1 7.4 4 2 3 8 8 8 6 Ankyrin repeats (many copies) F-box-like PF12937.2 GAO81999.1 - 2e-09 37.0 1.6 3e-08 33.2 0.1 3.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAO81999.1 - 7.5e-07 28.6 0.1 7.5e-07 28.6 0.1 2.5 4 0 0 4 4 4 1 F-box domain Polysacc_lyase PF14099.1 GAO82000.1 - 1.4e-22 80.4 0.1 1.7e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.1 GAO82000.1 - 7.7e-05 22.9 0.1 0.0001 22.5 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Phenol_MetA_deg PF13557.1 GAO82000.1 - 0.075 12.8 0.5 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation Ank_2 PF12796.2 GAO82003.1 - 3.9e-21 75.1 0.7 2.2e-16 59.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82003.1 - 8.4e-19 66.3 0.2 3.3e-06 26.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAO82003.1 - 1.3e-18 67.0 0.7 8.3e-07 29.3 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO82003.1 - 7.3e-16 57.8 0.1 6.3e-08 32.6 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82003.1 - 2.4e-15 55.0 0.0 0.00034 20.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Pectate_lyase PF03211.8 GAO82004.1 - 2e-67 226.7 7.3 2.5e-67 226.4 5.1 1.0 1 0 0 1 1 1 1 Pectate lyase Lipocalin_7 PF14651.1 GAO82004.1 - 0.14 11.8 1.4 0.14 11.8 0.2 1.6 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Glug PF07581.7 GAO82004.1 - 0.17 12.1 2.1 0.54 10.5 0.5 2.5 2 0 0 2 2 2 0 The GLUG motif NmrA PF05368.8 GAO82005.1 - 9.1e-33 113.4 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO82005.1 - 4.2e-08 33.4 0.0 7.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO82005.1 - 3.2e-05 22.7 0.0 5.8e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO82005.1 - 0.00036 20.0 0.0 0.0012 18.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAO82005.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 GAO82005.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82005.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAO82005.1 - 0.029 14.3 0.1 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 GAO82005.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ank_2 PF12796.2 GAO82010.1 - 1.7e-58 194.9 4.1 8.1e-17 61.3 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82010.1 - 3.2e-51 168.6 7.4 4.3e-07 29.4 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 GAO82010.1 - 3.6e-44 148.3 5.4 5.9e-11 42.5 0.0 6.7 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82010.1 - 1.2e-36 121.0 2.6 0.00032 20.6 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 GAO82010.1 - 6.7e-31 105.6 14.4 5e-09 36.1 0.0 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 GAO82010.1 - 0.027 13.9 0.0 17 4.7 0.0 3.5 3 2 1 4 4 4 0 Shigella flexneri OspC protein T2SE PF00437.15 GAO82010.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UbiA PF01040.13 GAO82011.1 - 1.7e-36 125.7 20.1 2.3e-36 125.3 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiD PF01977.11 GAO82012.1 - 1.6e-09 36.7 0.2 1.2e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Cpn10 PF00166.16 GAO82014.1 - 2.6e-12 46.4 0.2 4e-12 45.8 0.1 1.4 1 1 0 1 1 1 1 Chaperonin 10 Kd subunit Hydrophobin PF01185.13 GAO82014.1 - 2.7e-07 30.9 11.1 4.7e-07 30.1 7.7 1.4 1 0 0 1 1 1 1 Fungal hydrophobin DUF3104 PF11302.3 GAO82014.1 - 0.11 11.8 0.2 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) HAD_2 PF13419.1 GAO82015.1 - 7.8e-30 104.3 0.1 9.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO82015.1 - 0.00093 19.6 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 GAO82016.1 - 1.2e-104 350.3 35.8 1.4e-104 350.1 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO82016.1 - 1.2e-37 129.4 36.3 1.6e-37 129.0 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.19 GAO82017.1 - 2.6e-53 181.1 0.5 3.1e-53 180.9 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO82017.1 - 6.7e-05 22.8 0.4 0.00019 21.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO82017.1 - 0.00079 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAO82017.1 - 0.0017 18.1 0.2 0.007 16.1 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO82017.1 - 0.0021 18.1 0.0 0.044 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO82017.1 - 0.003 17.4 0.1 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO82017.1 - 0.0064 16.8 0.1 0.19 12.1 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO82017.1 - 0.022 13.6 0.1 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO82017.1 - 0.049 12.4 0.8 0.087 11.6 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain UCR_14kD PF02271.11 GAO82017.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit GIDA PF01134.17 GAO82017.1 - 0.12 11.2 0.3 0.17 10.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.13 GAO82018.1 - 1.7e-21 76.2 0.2 2.8e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO82018.1 - 5.1e-06 26.3 10.6 1e-05 25.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCL_N PF04714.8 GAO82018.1 - 1.5 8.4 7.8 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region zf-DHHC PF01529.15 GAO82019.1 - 1.6e-15 56.9 18.0 1.1e-14 54.2 4.7 3.0 4 0 0 4 4 4 2 DHHC palmitoyltransferase DUF4636 PF15468.1 GAO82019.1 - 0.38 10.1 4.2 0.69 9.3 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) HATPase_c PF02518.21 GAO82020.1 - 7.2e-12 45.0 0.0 1.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 GAO82020.1 - 1.8e-11 43.5 0.0 4.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAO82020.1 - 2.4e-09 36.9 0.0 5.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1295 PF06966.7 GAO82021.1 - 1.3e-30 106.4 0.3 2e-30 105.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 GAO82021.1 - 2.8e-05 24.1 0.3 0.00013 22.0 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 GAO82021.1 - 0.00017 21.6 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 GAO82021.1 - 0.0042 16.8 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.12 GAO82021.1 - 0.015 13.8 0.1 0.028 12.9 0.0 1.4 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family DUF3007 PF11460.3 GAO82021.1 - 0.061 13.4 0.1 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF2534 PF10749.4 GAO82021.1 - 0.1 12.5 0.8 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Cytochrom_B561 PF03188.11 GAO82022.1 - 3.8e-06 26.7 11.0 3.8e-06 26.7 7.7 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 GAO82022.1 - 4.5e-06 26.6 0.1 8.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 GAO82022.1 - 0.00063 19.2 5.9 0.0018 17.8 4.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2306 PF10067.4 GAO82022.1 - 0.052 13.6 0.6 0.052 13.6 0.4 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) PPV_E2_C PF00511.12 GAO82022.1 - 0.22 11.5 0.6 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 E2 (early) protein, C terminal EphA2_TM PF14575.1 GAO82022.1 - 0.37 11.1 0.0 0.37 11.1 0.0 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ferric_reduct PF01794.14 GAO82022.1 - 7.6 6.6 11.5 0.7 9.9 2.6 2.7 1 1 1 2 2 2 0 Ferric reductase like transmembrane component 2-Hacid_dh_C PF02826.14 GAO82023.1 - 9.4e-39 132.3 0.2 3.3e-26 91.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2874 PF11396.3 GAO82023.1 - 0.076 12.9 0.2 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) 2-Hacid_dh PF00389.25 GAO82023.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 GAO82023.1 - 0.097 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-rbx1 PF12678.2 GAO82023.1 - 0.15 12.1 0.0 4 7.6 0.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger DUF4231 PF14015.1 GAO82024.1 - 0.00051 20.0 0.1 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Claudin_2 PF13903.1 GAO82024.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Acetyltransf_1 PF00583.19 GAO82025.1 - 7.8e-11 41.8 0.1 1.4e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO82025.1 - 2.4e-09 37.2 0.0 5.4e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO82025.1 - 1.9e-08 34.4 0.1 6.7e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO82025.1 - 3.5e-07 30.1 0.1 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO82025.1 - 0.022 14.4 0.0 0.075 12.7 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 GAO82025.1 - 0.042 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_N PF08240.7 GAO82026.1 - 2.9e-32 110.6 0.4 2.9e-32 110.6 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO82026.1 - 3.9e-15 55.5 2.0 4.6e-15 55.3 0.1 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 GAO82026.1 - 0.00042 20.0 0.2 0.00062 19.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAO82026.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 GAO82026.1 - 0.003 17.1 0.1 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 GAO82026.1 - 0.0043 16.3 0.1 0.006 15.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AdoHcyase_NAD PF00670.16 GAO82026.1 - 0.0089 15.8 0.4 0.027 14.3 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAO82026.1 - 0.012 16.4 0.0 0.034 15.0 0.0 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 GAO82026.1 - 0.03 14.7 0.2 0.091 13.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAO82026.1 - 0.037 13.8 0.4 0.07 12.9 0.3 1.5 1 1 0 1 1 1 0 ThiF family HI0933_like PF03486.9 GAO82026.1 - 0.074 11.5 0.1 0.099 11.0 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Peptidase_M24 PF00557.19 GAO82026.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Metallopeptidase family M24 FAD_binding_2 PF00890.19 GAO82026.1 - 0.098 11.4 0.3 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_18 PF12847.2 GAO82026.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 GAO82027.1 - 1.6e-69 233.9 0.0 3.2e-69 232.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82027.1 - 1.3e-44 152.2 0.0 1.9e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO82027.1 - 4.3e-09 35.7 0.0 7.4e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 GAO82027.1 - 5.1e-08 32.7 0.1 0.003 17.5 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Myosin_head PF00063.16 GAO82028.1 - 7.3e-232 771.2 3.3 1.1e-231 770.7 2.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAO82028.1 - 3.8e-50 169.9 0.0 6.9e-50 169.1 0.0 1.5 1 0 0 1 1 1 1 Myosin tail OPA3 PF07047.7 GAO82028.1 - 8.7e-29 99.9 3.8 1.5e-28 99.1 2.0 1.9 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.23 GAO82028.1 - 3.8e-14 51.7 0.1 7.7e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO82028.1 - 1e-09 37.8 0.0 2.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO82028.1 - 1.4e-09 37.2 0.0 3.4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 GAO82028.1 - 0.0053 16.2 7.0 0.6 9.9 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 GAO82028.1 - 0.0075 16.4 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO82028.1 - 0.077 13.8 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 GAO82028.1 - 0.11 11.7 0.5 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 GAO82028.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF3759 PF12585.3 GAO82029.1 - 0.031 14.1 3.5 0.056 13.3 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) WD40 PF00400.27 GAO82030.1 - 3.7e-09 36.1 0.5 7.9e-08 31.8 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Chitin_synth_2 PF03142.10 GAO82031.1 - 1.5e-293 974.0 0.2 2.2e-293 973.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAO82031.1 - 2.7e-18 66.4 0.8 1.1e-17 64.3 0.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO82031.1 - 2.4e-15 56.9 0.0 2.4e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 GAO82031.1 - 3.3e-08 33.1 0.1 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 GAO82031.1 - 3.8e-05 23.0 0.0 0.0003 20.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAO82031.1 - 4.4e-05 23.2 0.1 0.0057 16.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 GAO82032.1 - 1.3e-36 124.2 34.7 1.8e-06 28.3 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat Glyco_hydro_17 PF00332.13 GAO82034.1 - 0.0002 20.5 0.9 0.33 9.9 0.2 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 adh_short_C2 PF13561.1 GAO82037.1 - 2.7e-22 79.7 0.0 5.3e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82037.1 - 1.7e-08 34.5 2.1 7e-08 32.5 0.1 2.4 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAO82037.1 - 7.9e-06 25.6 0.2 2.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAO82037.1 - 3.4e-05 23.9 0.2 0.00012 22.1 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAO82037.1 - 0.0016 18.1 0.3 0.0029 17.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 GAO82037.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_Coat_B PF05356.6 GAO82037.1 - 0.048 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Phage Coat protein B MEDS PF14417.1 GAO82037.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AcetylCoA_hydro PF02550.10 GAO82038.1 - 2.2e-52 177.7 0.0 3.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 GAO82038.1 - 7.9e-40 136.0 0.0 1.4e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PAH PF02671.16 GAO82039.1 - 5.4e-46 153.9 1.1 6.2e-17 60.9 0.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 GAO82039.1 - 3.5e-40 135.8 0.1 8.2e-40 134.6 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor WD40 PF00400.27 GAO82040.1 - 5.7e-14 51.3 2.0 0.07 13.0 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat FAD_binding_2 PF00890.19 GAO82042.1 - 4.9e-84 282.5 0.9 6.1e-84 282.2 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 GAO82042.1 - 2.5e-22 78.4 0.5 4e-20 71.4 0.1 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 GAO82042.1 - 2e-11 43.4 3.2 1.1e-10 40.9 2.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO82042.1 - 6.6e-09 35.3 1.7 2.4e-08 33.5 1.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO82042.1 - 7.2e-09 35.5 0.2 8.9e-08 32.0 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO82042.1 - 1.3e-08 34.9 0.0 1.5e-06 28.1 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO82042.1 - 2.1e-07 29.7 2.2 0.0032 15.9 0.1 3.2 3 0 0 3 3 3 3 HI0933-like protein Thi4 PF01946.12 GAO82042.1 - 5.6e-06 25.6 0.2 0.0054 15.8 0.0 2.6 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 GAO82042.1 - 0.00048 19.3 1.4 0.00097 18.2 1.0 1.4 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 GAO82042.1 - 0.00063 18.7 1.5 0.12 11.1 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAO82042.1 - 0.00087 18.4 0.6 0.22 10.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAO82042.1 - 0.0034 17.1 0.8 0.028 14.1 0.5 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO82042.1 - 0.012 15.6 0.9 0.029 14.4 0.6 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO82042.1 - 0.46 10.9 5.6 6 7.3 1.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 GAO82043.1 - 3.3e-135 451.0 1.0 3.9e-135 450.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO82043.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PCI PF01399.22 GAO82045.1 - 2.3e-12 47.1 0.0 7.8e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 GAO82045.1 - 6.4e-08 32.1 0.2 1.1e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 GAO82045.1 - 0.00088 19.5 0.3 0.007 16.6 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO82045.1 - 0.0046 17.4 0.8 6.4 7.7 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 GAO82045.1 - 0.038 13.9 4.2 0.053 13.4 1.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82045.1 - 0.073 12.8 0.1 8.3 6.4 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PilJ PF13675.1 GAO82045.1 - 0.11 12.8 4.1 0.15 12.4 0.3 2.8 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RRM_1 PF00076.17 GAO82045.1 - 0.14 11.8 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_beta PF02270.10 GAO82046.1 - 1.7e-84 283.8 0.6 2.1e-84 283.5 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 GAO82047.1 - 0.74 9.5 5.0 8 6.2 0.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) bZIP_2 PF07716.10 GAO82048.1 - 5.1e-06 26.2 10.7 5.1e-06 26.2 7.4 2.9 2 1 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 GAO82048.1 - 1.4e-05 25.3 14.6 1.4e-05 25.3 10.1 2.9 1 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 GAO82048.1 - 4.2e-05 23.4 23.1 0.00012 21.9 11.0 2.6 2 0 0 2 2 2 2 bZIP transcription factor Endotoxin_N PF03945.9 GAO82048.1 - 1.3 8.3 11.4 0.21 10.9 3.6 2.3 1 1 0 2 2 2 0 delta endotoxin, N-terminal domain Sel1 PF08238.7 GAO82049.1 - 1.2e-18 67.0 2.6 6.8e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat Polysacc_lyase PF14099.1 GAO82049.1 - 0.0032 17.1 0.2 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase NODP PF07684.7 GAO82049.1 - 0.15 11.7 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 NOTCH protein TPR_12 PF13424.1 GAO82049.1 - 0.16 11.8 0.5 5.1 7.1 0.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 GAO82050.1 - 9.9e-53 177.9 8.2 1.2e-52 177.6 5.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4034 PF13226.1 GAO82050.1 - 0.042 12.9 1.9 1.7 7.6 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4034) CBF PF03914.12 GAO82051.1 - 4.1e-47 159.6 1.3 5.3e-47 159.3 0.2 1.7 2 0 0 2 2 2 1 CBF/Mak21 family RIX1 PF08167.7 GAO82051.1 - 0.04 13.5 1.4 11 5.6 0.0 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis LemA PF04011.7 GAO82051.1 - 0.065 12.3 1.3 0.65 9.0 0.0 2.7 3 0 0 3 3 3 0 LemA family DUF1395 PF07160.7 GAO82052.1 - 0.024 14.1 0.3 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) GLTP PF08718.6 GAO82052.1 - 0.031 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) TetR_C_6 PF13977.1 GAO82052.1 - 0.032 14.2 0.4 0.084 12.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor Corona_S2 PF01601.11 GAO82052.1 - 0.05 11.7 0.1 0.075 11.1 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Piwi PF02171.12 GAO82052.1 - 0.076 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Piwi domain Mitofilin PF09731.4 GAO82052.1 - 0.43 9.1 4.7 0.6 8.7 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GPI-anchored PF10342.4 GAO82053.1 - 7.3e-15 55.2 0.1 1.7e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.1 GAO82053.1 - 0.015 15.8 2.2 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 Bacterial Ig-like domain bZIP_C PF12498.3 GAO82053.1 - 0.12 13.6 1.8 0.17 13.0 1.3 1.3 1 0 0 1 1 1 0 Basic leucine-zipper C terminal HpaP PF09483.5 GAO82053.1 - 2.8 7.8 5.3 4.4 7.2 3.7 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) APG6 PF04111.7 GAO82054.1 - 8.7e-05 21.7 16.9 8.7e-05 21.7 11.7 2.2 1 1 1 2 2 2 1 Autophagy protein Apg6 ISG65-75 PF11727.3 GAO82054.1 - 0.00013 21.1 8.2 0.00013 21.1 5.7 2.0 1 1 1 2 2 2 1 Invariant surface glycoprotein Filament PF00038.16 GAO82054.1 - 0.0056 16.1 32.3 0.19 11.1 16.1 2.6 1 1 1 2 2 2 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 GAO82054.1 - 0.0063 16.2 15.2 0.0063 16.2 10.5 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Tup_N PF08581.5 GAO82054.1 - 0.023 14.8 26.6 0.054 13.6 2.7 3.4 2 1 1 3 3 3 0 Tup N-terminal Cep57_MT_bd PF06657.8 GAO82054.1 - 0.036 13.9 13.6 0.28 11.1 0.9 4.1 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Reo_sigmaC PF04582.7 GAO82054.1 - 0.042 13.0 0.2 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMPIT PF07851.8 GAO82054.1 - 0.43 9.5 18.2 1.3 8.0 4.9 2.3 2 1 0 2 2 2 0 TMPIT-like protein DUF3775 PF12616.3 GAO82054.1 - 0.6 9.9 6.1 42 4.0 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3775) BLOC1_2 PF10046.4 GAO82054.1 - 0.63 10.2 16.8 0.17 12.0 3.2 3.6 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 GAO82054.1 - 0.66 8.5 26.8 0.61 8.7 7.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 GAO82054.1 - 0.73 9.3 31.8 0.026 14.1 10.7 2.2 1 1 1 2 2 2 0 IncA protein TMCO5 PF14992.1 GAO82054.1 - 0.92 8.5 22.4 0.11 11.6 8.4 2.1 1 1 1 2 2 2 0 TMCO5 family Atg14 PF10186.4 GAO82054.1 - 0.95 8.3 29.7 1.5 7.7 11.4 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 GAO82054.1 - 1.3 8.2 22.4 1.3 8.2 3.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Noelin-1 PF12308.3 GAO82054.1 - 1.4 8.7 8.6 0.14 12.0 1.8 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein ERM PF00769.14 GAO82054.1 - 1.7 8.1 35.6 0.58 9.6 21.3 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family COG2 PF06148.6 GAO82054.1 - 2.7 7.8 16.9 1.9 8.3 0.0 3.8 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.1 GAO82054.1 - 3.7 7.5 40.9 0.45 10.4 7.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF2265 PF10023.4 GAO82054.1 - 3.7 6.5 18.4 7.8 5.5 6.1 2.2 1 1 1 2 2 2 0 Predicted aminopeptidase (DUF2265) TMF_TATA_bd PF12325.3 GAO82054.1 - 4.7 6.9 24.6 0.031 14.0 6.1 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 GAO82054.1 - 7.6 6.3 21.8 0.22 11.3 4.7 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 GAO82054.1 - 8.2 6.3 34.0 0.18 11.7 8.8 3.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Trypan_PARP PF05887.6 GAO82055.1 - 0.11 12.3 10.7 0.27 11.0 7.4 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MMS19_C PF12460.3 GAO82056.1 - 1.9e-130 435.3 14.4 2.5e-129 431.6 3.8 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 GAO82056.1 - 3.8e-97 324.6 0.1 5.6e-96 320.8 0.0 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 GAO82056.1 - 7.8e-08 32.4 14.0 1 9.7 0.2 7.4 8 0 0 8 8 8 3 HEAT repeats HEAT PF02985.17 GAO82056.1 - 0.00047 19.9 14.9 6.5 7.1 0.2 7.7 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 GAO82056.1 - 0.0021 17.8 0.5 1.3 8.9 0.0 4.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAO82056.1 - 0.16 12.5 22.5 5.9 7.5 0.7 7.1 7 1 0 7 7 7 0 HEAT-like repeat CLASP_N PF12348.3 GAO82056.1 - 1.2 8.4 6.2 4.9 6.4 0.0 4.5 5 0 0 5 5 5 0 CLASP N terminal Fasciclin PF02469.17 GAO82057.1 - 5.5e-07 29.6 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 GAO82058.1 - 5.5e-56 188.7 1.2 7.2e-56 188.3 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 GAO82059.1 - 2.7e-49 166.8 0.0 3.1e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PI3Ka PF00613.15 GAO82059.1 - 0.037 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) THF_DHG_CYH PF00763.18 GAO82060.1 - 1.9e-19 69.8 0.1 2.9e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 GAO82060.1 - 4.6e-13 48.5 0.1 9.2e-11 41.0 0.1 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 GAO82061.1 - 7.2e-71 238.1 0.0 1.1e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAO82061.1 - 4.2e-26 91.6 0.1 1.4e-25 89.9 0.0 2.0 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAO82061.1 - 2.3e-15 56.5 3.1 7e-15 55.0 2.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAO82061.1 - 0.016 15.1 3.0 0.017 15.0 0.6 2.2 2 0 0 2 2 2 0 HAS barrel domain DUF962 PF06127.6 GAO82062.1 - 2.8e-14 52.7 0.9 5.2e-14 51.8 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) RDD PF06271.7 GAO82062.1 - 0.17 11.7 5.6 1.8 8.4 4.6 2.0 1 1 1 2 2 2 0 RDD family DUF4282 PF14110.1 GAO82062.1 - 2.1 8.5 4.6 0.57 10.4 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) SHS2_Rpb7-N PF03876.12 GAO82063.1 - 2.1e-15 56.5 0.0 4.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAO82063.1 - 3.4e-08 33.4 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Piwi PF02171.12 GAO82064.1 - 9.9e-75 251.3 0.0 1.5e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 GAO82064.1 - 5.7e-13 48.0 0.0 1.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 GAO82064.1 - 7e-10 38.3 0.0 1.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain RRM_1 PF00076.17 GAO82065.1 - 2e-35 120.2 0.1 7.1e-19 67.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82065.1 - 2.2e-30 104.4 1.0 1.3e-16 60.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 GAO82065.1 - 4.6e-16 58.4 0.0 7.8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_5 PF13893.1 GAO82065.1 - 1.5e-15 56.7 0.0 5.9e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 GAO82065.1 - 0.019 14.2 0.1 0.09 12.1 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.3 GAO82065.1 - 0.1 12.3 0.2 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_3 PF08777.6 GAO82065.1 - 0.13 12.1 0.1 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif TPR_11 PF13414.1 GAO82066.1 - 3.9e-26 90.4 3.2 5.1e-11 42.0 0.2 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 GAO82066.1 - 1.5e-23 81.3 2.3 1e-08 34.4 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAO82066.1 - 2.3e-22 77.0 2.3 4.5e-07 29.2 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO82066.1 - 3.8e-18 64.3 4.8 3.7e-05 23.9 0.0 6.1 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAO82066.1 - 1.1e-16 60.9 2.7 6.2e-06 26.7 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAO82066.1 - 1e-15 56.5 3.7 0.0032 17.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAO82066.1 - 1.8e-13 50.6 3.1 0.00023 21.4 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO82066.1 - 1e-11 44.6 7.8 4.3e-08 32.9 0.2 4.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 GAO82066.1 - 4.8e-11 42.6 0.3 0.0023 18.0 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82066.1 - 7.5e-11 41.0 0.2 0.0003 20.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO82066.1 - 1.1e-10 40.4 1.8 0.00074 19.1 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAO82066.1 - 2.2e-07 30.6 4.4 0.0028 17.4 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAO82066.1 - 1.9e-06 27.9 1.4 0.00017 21.6 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAO82066.1 - 3.5e-05 23.9 3.1 1.5 9.4 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAO82066.1 - 0.00025 20.7 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAO82066.1 - 0.001 18.1 0.3 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAO82066.1 - 0.0025 17.7 1.1 0.17 11.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 GAO82066.1 - 0.0099 15.4 0.2 2 7.9 0.0 3.2 3 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 NatB_MDM20 PF09797.4 GAO82066.1 - 0.059 12.0 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit MIT PF04212.13 GAO82066.1 - 0.11 12.4 1.3 3.5 7.5 0.3 3.5 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.6 GAO82066.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4192 PF13830.1 GAO82066.1 - 4.7 6.7 8.2 2.7 7.5 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) TPP_enzyme_N PF02776.13 GAO82067.1 - 1e-45 155.3 0.2 3.4e-45 153.6 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO82067.1 - 3.2e-38 130.5 0.0 7.8e-38 129.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAO82067.1 - 6.5e-17 61.5 0.0 1.5e-15 57.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 GAO82067.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Amidase PF01425.16 GAO82068.1 - 4e-91 306.0 0.0 5.1e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_28 PF02636.12 GAO82069.1 - 1.7e-35 122.6 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.20 GAO82070.1 - 3.9e-54 183.9 0.2 4.6e-54 183.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 GAO82071.1 - 3.1e-24 84.2 0.8 6.6e-24 83.1 0.6 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 GAO82071.1 - 3.8e-06 26.9 2.2 0.013 15.5 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO82071.1 - 0.002 18.1 1.1 0.14 12.1 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain APG6 PF04111.7 GAO82072.1 - 1e-130 435.4 0.0 1.2e-130 435.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 bZIP_2 PF07716.10 GAO82072.1 - 1.2 9.0 5.2 3.6 7.4 3.6 1.9 1 0 0 1 1 1 0 Basic region leucine zipper FliT PF05400.8 GAO82072.1 - 4.4 7.7 12.3 3.7 8.0 6.9 2.0 1 1 1 2 2 2 0 Flagellar protein FliT Peroxin-13_N PF04088.8 GAO82074.1 - 3.4e-61 205.8 0.0 5.2e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 GAO82074.1 - 6.3e-09 35.1 0.0 1.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO82074.1 - 4.4e-08 32.3 0.0 7.4e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO82074.1 - 1.9e-07 30.5 0.1 3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ERO1 PF04137.10 GAO82075.1 - 2.4e-140 467.5 0.0 3e-140 467.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PRY PF13765.1 GAO82075.1 - 0.096 12.2 0.1 6.3 6.4 0.0 3.1 3 0 0 3 3 3 0 SPRY-associated domain Abhydrolase_5 PF12695.2 GAO82076.1 - 0.0002 21.1 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO82076.1 - 0.03 14.2 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pal1 PF08316.6 GAO82077.1 - 4.6e-09 36.8 0.1 8.3e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 GAO82078.1 - 3.4e-82 275.0 0.0 5e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 GAO82078.1 - 4.3e-46 157.2 4.6 4.3e-46 157.2 3.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3807) MFS_1 PF07690.11 GAO82079.1 - 1e-25 90.2 53.0 5e-18 64.9 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO82079.1 - 1.1e-06 27.3 33.0 1.4e-06 27.0 12.5 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 GAO82079.1 - 0.17 11.9 11.4 0.94 9.5 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Aa_trans PF01490.13 GAO82080.1 - 2.1e-45 154.9 37.8 2.5e-45 154.6 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAS4 PF15460.1 GAO82081.1 - 6e-35 119.1 9.4 1.4e-34 117.9 6.5 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHDPS PF00701.17 GAO82082.1 - 4.7e-52 176.3 0.0 5.4e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF4396 PF14342.1 GAO82083.1 - 1.6e-40 138.4 7.2 2.3e-40 137.9 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Glyco_hydro_20 PF00728.17 GAO82084.1 - 7.6e-98 327.8 4.2 1e-97 327.4 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAO82084.1 - 2.2e-22 80.0 0.1 4.7e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAO82084.1 - 6.8e-06 26.6 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ATP_transf PF09830.4 GAO82085.1 - 5.6e-23 80.5 0.0 9.5e-23 79.7 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C2H2_4 PF13894.1 GAO82085.1 - 0.0003 20.9 15.9 0.14 12.5 0.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO82085.1 - 0.0022 18.2 19.1 1.2 9.6 0.1 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type GalP_UDP_transf PF01087.17 GAO82085.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-C2H2_6 PF13912.1 GAO82085.1 - 0.031 14.2 0.6 0.37 10.7 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 GAO82085.1 - 0.2 11.8 1.6 5.4 7.3 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NTR2 PF15458.1 GAO82087.1 - 3.2e-77 259.2 22.5 4.8e-77 258.6 15.6 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LtrA PF06772.6 GAO82087.1 - 2e-15 56.5 18.0 2e-15 56.5 12.5 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) PGA2 PF07543.7 GAO82087.1 - 6 6.6 11.9 21 4.9 8.3 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 LSM PF01423.17 GAO82088.1 - 7.4e-20 70.2 0.3 8.4e-20 70.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 GAO82089.1 - 3.7e-06 26.2 0.0 0.13 11.3 0.0 3.3 2 1 0 3 3 3 3 Peptidase family M1 CDP-OH_P_transf PF01066.16 GAO82090.1 - 6.3e-14 52.1 4.1 6.3e-14 52.1 2.8 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3659 PF12396.3 GAO82091.1 - 2.7e-239 773.2 119.2 1.7e-24 85.2 3.8 11.5 11 0 0 11 11 11 11 Protein of unknown function (DUF3659) DUF883 PF05957.8 GAO82091.1 - 0.0034 17.7 7.4 0.0034 17.7 5.1 4.9 5 0 0 5 5 5 1 Bacterial protein of unknown function (DUF883) YlqD PF11068.3 GAO82091.1 - 0.015 15.3 1.3 0.015 15.3 0.9 3.4 3 0 0 3 3 3 0 YlqD protein YtxH PF12732.2 GAO82091.1 - 0.26 11.6 40.9 0.29 11.5 9.7 6.1 5 3 1 6 6 6 0 YtxH-like protein Transpep_BrtH PF14399.1 GAO82091.1 - 2.3 7.4 4.0 4.3 6.5 2.1 2.0 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase AA_permease_2 PF13520.1 GAO82092.1 - 2.7e-52 177.7 48.3 2.7e-52 177.7 33.5 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAO82092.1 - 1.2e-16 60.0 39.8 3e-16 58.8 27.5 1.5 1 1 0 1 1 1 1 Amino acid permease Transglycosylas PF06737.9 GAO82092.1 - 0.043 14.0 0.1 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase-like domain PX PF00787.19 GAO82093.1 - 1.8e-19 69.6 0.0 2.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 PX domain RPN7 PF10602.4 GAO82094.1 - 1.8e-55 187.0 0.0 3.1e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAO82094.1 - 1.7e-10 41.1 0.1 7.6e-10 39.0 0.0 2.2 3 0 0 3 3 3 1 PCI domain PilX PF13681.1 GAO82094.1 - 0.25 11.8 5.0 0.55 10.7 3.4 1.6 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term GFO_IDH_MocA PF01408.17 GAO82095.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAO82095.1 - 0.00021 21.5 0.0 0.00075 19.7 0.0 1.8 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 GAO82095.1 - 0.002 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 GAO82095.1 - 0.14 12.0 0.0 0.71 9.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain Dehydrin PF00257.14 GAO82097.1 - 0.18 12.1 2.1 0.23 11.7 1.5 1.2 1 0 0 1 1 1 0 Dehydrin RunxI PF08504.6 GAO82097.1 - 2.1 8.8 9.6 2.1 8.8 4.8 2.1 2 0 0 2 2 2 0 Runx inhibition domain Sporozoite_P67 PF05642.6 GAO82097.1 - 3.7 5.2 14.8 4 5.1 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 GAO82098.1 - 0.00012 20.2 1.4 0.00012 20.2 1.0 1.2 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 GAO82098.1 - 0.17 10.9 14.3 0.28 10.2 9.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TLP-20 PF06088.6 GAO82098.1 - 0.56 9.8 4.7 0.94 9.1 3.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2457 PF10446.4 GAO82098.1 - 2.9 6.5 21.0 3.6 6.2 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 GAO82098.1 - 3.7 6.1 15.6 5.1 5.7 10.8 1.1 1 0 0 1 1 1 0 Paf1 RNA_pol_3_Rpc31 PF11705.3 GAO82098.1 - 6.7 6.5 23.2 11 5.8 16.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MFS_1 PF07690.11 GAO82099.1 - 3.7e-13 48.9 27.3 1.7e-11 43.4 13.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO82099.1 - 0.19 10.0 8.7 0.73 8.1 4.3 2.8 1 1 1 2 2 2 0 MFS/sugar transport protein zf-rbx1 PF12678.2 GAO82100.1 - 1.3e-11 44.4 0.7 2.6e-11 43.4 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAO82100.1 - 8.1e-11 41.5 4.7 4.5e-10 39.1 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAO82100.1 - 1.7e-07 30.7 0.1 4.2e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO82100.1 - 1.3e-06 27.9 4.9 9.6e-06 25.1 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO82100.1 - 2e-05 24.4 2.5 2e-05 24.4 1.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO82100.1 - 6.8e-05 22.5 3.7 0.00045 19.8 2.8 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAO82100.1 - 0.00021 20.9 2.4 0.00057 19.5 1.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAO82100.1 - 0.021 14.6 1.3 0.05 13.4 0.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 GAO82100.1 - 0.032 14.0 5.7 0.53 10.1 3.9 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAO82100.1 - 3.7 7.2 5.5 0.58 9.7 1.1 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.3 GAO82101.1 - 8.8e-93 309.8 0.1 1.3e-92 309.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RNase_P_p30 PF01876.11 GAO82103.1 - 3.1e-51 172.5 0.0 4.4e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 GAO82104.1 - 5.5e-55 186.3 0.1 6.4e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82104.1 - 2.1e-20 72.8 0.0 2.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO82104.1 - 1.7e-08 34.4 0.4 9.1e-05 22.3 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO82104.1 - 0.0077 15.8 0.1 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 GAO82104.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAO82104.1 - 0.032 13.2 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAO82104.1 - 0.06 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1 PF00133.17 GAO82105.1 - 1.5e-219 729.9 0.0 7.7e-219 727.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAO82105.1 - 7.6e-34 116.6 0.7 2.1e-33 115.2 0.5 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAO82105.1 - 1.1e-17 63.7 0.0 8.8e-08 31.2 0.0 4.9 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAO82105.1 - 2e-08 33.7 0.0 0.00012 21.4 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAO82105.1 - 0.029 13.4 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Brix PF04427.13 GAO82106.1 - 6.3e-32 110.7 0.0 8.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 GAO82107.1 - 1.2e-24 86.7 0.9 2.1e-24 86.0 0.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2207 PF09972.4 GAO82107.1 - 0.02 13.4 0.4 0.024 13.2 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BTB PF00651.26 GAO82108.1 - 2.2e-13 50.1 0.0 7.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF287 PF03384.9 GAO82108.1 - 0.032 14.3 0.9 0.072 13.2 0.2 1.9 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 AMP-binding PF00501.23 GAO82109.1 - 7.2e-46 156.4 0.0 1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ureidogly_hydro PF04115.7 GAO82110.1 - 1.1e-56 190.7 0.0 1.3e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MutS_V PF00488.16 GAO82111.1 - 9.7e-85 283.7 0.0 1.6e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO82111.1 - 1.2e-40 139.4 7.4 2.7e-40 138.3 5.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAO82111.1 - 2.4e-21 75.8 0.0 6.3e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAO82111.1 - 1.4e-07 31.6 0.0 3.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAO82111.1 - 8.9e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 GAO82111.1 - 0.032 13.7 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAO82111.1 - 0.074 13.3 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO82111.1 - 0.31 11.2 2.0 8.4 6.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain Sec63 PF02889.11 GAO82112.1 - 2.1e-196 651.3 0.0 7.6e-109 363.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAO82112.1 - 1.3e-55 187.5 0.0 1.6e-30 105.8 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 GAO82112.1 - 1.5e-15 57.4 0.0 2.2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAO82112.1 - 1.8e-09 37.2 0.0 1e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAO82112.1 - 1.1e-05 25.6 1.5 0.029 14.5 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 GAO82112.1 - 0.00072 19.0 0.6 4.6 6.6 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain AAA_19 PF13245.1 GAO82112.1 - 0.002 17.8 0.0 0.83 9.4 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain PhoH PF02562.11 GAO82112.1 - 0.0025 17.0 0.0 0.76 8.9 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 GAO82112.1 - 0.006 15.5 0.0 0.69 8.7 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 GAO82112.1 - 0.022 14.9 0.5 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_S9 PF00326.16 GAO82113.1 - 9.5e-50 168.7 0.0 1.6e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO82113.1 - 2.3e-08 33.8 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO82113.1 - 2.9e-06 27.3 0.8 1.4e-05 25.1 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO82113.1 - 4.7e-05 22.0 0.0 0.0086 14.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DUF605 PF04652.11 GAO82114.1 - 9.8 5.4 8.8 12 5.1 6.1 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_43 PF04616.9 GAO82115.1 - 3.1e-28 98.7 3.7 1.2e-26 93.5 2.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 GAO82116.1 - 3.6e-27 95.0 29.1 3.6e-27 95.0 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 GAO82117.1 - 2.9e-07 30.5 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82117.1 - 7.3e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1641 PF07849.6 GAO82117.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Pkinase PF00069.20 GAO82118.1 - 9.2e-39 133.1 0.0 2.5e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82118.1 - 3.4e-14 52.5 0.0 1.6e-12 47.0 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO82118.1 - 0.00096 18.1 0.0 0.82 8.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAO82118.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.20 GAO82119.1 - 2.1e-17 62.5 1.1 5.1e-17 61.3 0.8 1.7 1 0 0 1 1 1 1 CAP-Gly domain TMF_DNA_bd PF12329.3 GAO82119.1 - 0.00026 20.7 37.2 0.066 13.0 3.3 5.2 5 0 0 5 5 5 3 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 GAO82119.1 - 0.0025 18.5 15.8 0.95 10.2 1.9 3.5 3 0 0 3 3 3 2 Occludin homology domain AAA_13 PF13166.1 GAO82119.1 - 0.0033 15.9 13.4 0.0033 15.9 9.3 2.2 1 1 0 2 2 2 1 AAA domain Med4 PF10018.4 GAO82119.1 - 0.0041 16.5 1.1 0.0041 16.5 0.8 3.6 2 1 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3584 PF12128.3 GAO82119.1 - 0.021 12.2 27.5 0.0018 15.7 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 GAO82119.1 - 0.028 13.5 8.3 4.3 6.4 0.1 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 GAO82119.1 - 0.08 13.2 12.5 1.3 9.3 1.2 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.13 GAO82119.1 - 0.081 13.2 13.0 1.3 9.4 0.4 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Cast PF10174.4 GAO82119.1 - 0.37 8.7 40.1 0.46 8.4 0.8 2.5 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone SlyX PF04102.7 GAO82119.1 - 0.38 11.1 28.6 0.15 12.4 4.9 3.9 3 0 0 3 3 3 0 SlyX EzrA PF06160.7 GAO82119.1 - 0.39 8.8 26.5 0.051 11.7 7.6 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Pox_A_type_inc PF04508.7 GAO82119.1 - 0.53 10.2 16.2 1.2 9.0 1.3 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat BLOC1_2 PF10046.4 GAO82119.1 - 0.55 10.3 20.3 0.44 10.7 2.1 4.2 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 GAO82119.1 - 0.63 8.6 32.2 0.3 9.6 5.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF812 PF05667.6 GAO82119.1 - 0.71 8.3 31.5 0.072 11.5 11.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Mod_r PF07200.8 GAO82119.1 - 0.93 9.3 28.4 0.58 10.0 4.8 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 GAO82119.1 - 2.3 7.0 35.0 0.085 11.7 3.0 3.4 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 GAO82119.1 - 3.1 6.9 26.8 0.32 10.2 2.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Gp58 PF07902.6 GAO82119.1 - 3.4 5.7 7.8 5.3 5.1 5.4 1.4 1 1 0 1 1 1 0 gp58-like protein Tropomyosin PF00261.15 GAO82119.1 - 4.4 6.3 40.1 1.5 7.8 1.8 3.0 2 1 1 3 3 3 0 Tropomyosin DUF1664 PF07889.7 GAO82119.1 - 7.9 6.3 17.5 4.4 7.1 1.9 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 GAO82119.1 - 8.1 5.8 27.5 0.58 9.5 3.2 3.9 3 1 2 5 5 5 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 GAO82119.1 - 8.9 6.1 43.9 9.7 6.0 4.0 4.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3373 PF11853.3 GAO82119.1 - 9.4 4.6 15.4 0.98 7.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3373) 3-HAO PF06052.7 GAO82120.1 - 6.8e-54 181.3 0.0 8.2e-54 181.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAO82120.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DZR PF12773.2 GAO82120.1 - 0.005 16.6 1.8 0.017 14.8 1.3 1.9 1 1 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.17 GAO82120.1 - 0.014 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 GAO82120.1 - 0.021 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain FYVE PF01363.16 GAO82120.1 - 0.036 13.9 1.2 0.067 13.1 0.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger RNA_POL_M_15KD PF02150.11 GAO82120.1 - 0.046 13.4 1.0 6.5 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit A2L_zn_ribbon PF08792.5 GAO82120.1 - 0.047 13.1 1.5 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 GAO82120.1 - 0.15 11.2 1.0 9.5 5.5 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 GAO82120.1 - 0.38 10.7 2.7 4.3 7.3 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 GAO82120.1 - 0.5 10.0 6.2 11 5.8 0.7 3.0 1 1 1 2 2 2 0 Nudix N-terminal Baculo_LEF5_C PF11792.3 GAO82120.1 - 0.87 9.0 3.7 1.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Rpr2 PF04032.11 GAO82120.1 - 1.3 8.9 5.2 4.7 7.1 0.7 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADK_lid PF05191.9 GAO82120.1 - 2.8 7.6 5.1 15 5.3 0.2 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid RTC_insert PF05189.8 GAO82121.1 - 1.1e-32 112.0 0.0 1.9e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 GAO82121.1 - 2.8e-30 104.8 0.0 4.1e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase SLAC1 PF03595.12 GAO82122.1 - 3.5e-84 282.2 41.5 4e-84 282.0 28.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HSCB_C PF07743.8 GAO82124.1 - 1.9e-22 79.4 0.6 9e-22 77.3 0.1 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 GAO82124.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 GAO82125.1 - 1.6e-43 145.0 24.7 2.4e-09 36.7 0.2 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 GAO82125.1 - 2.4e-14 52.2 5.1 2.4e-14 52.2 3.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like PRTP PF01366.13 GAO82125.1 - 0.35 8.8 0.8 0.5 8.3 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein SpoIIE PF07228.7 GAO82126.1 - 6.3e-11 42.3 0.1 3.7e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAO82126.1 - 1.6e-10 40.7 0.0 2.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAO82126.1 - 1.2e-06 28.1 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PWWP PF00855.12 GAO82127.1 - 4e-16 59.0 1.6 3.6e-15 55.9 1.1 2.7 1 1 0 1 1 1 1 PWWP domain Med26 PF08711.6 GAO82127.1 - 0.082 12.4 0.3 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PAP2_3 PF14378.1 GAO82128.1 - 1.9e-22 79.7 11.9 1.2e-11 44.5 0.2 3.8 3 1 0 3 3 3 3 PAP2 superfamily MFS_1 PF07690.11 GAO82128.1 - 0.03 13.0 6.8 0.058 12.0 4.7 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily PAP2 PF01569.16 GAO82128.1 - 0.5 10.0 10.2 0.08 12.6 2.1 2.7 2 1 1 3 3 3 0 PAP2 superfamily PAP2_C PF14360.1 GAO82128.1 - 2.2 8.6 7.8 0.3 11.3 0.2 2.8 2 1 0 2 2 2 0 PAP2 superfamily C-terminal ComA PF02679.10 GAO82129.1 - 7.2e-65 218.4 0.0 1.1e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Fungal_trans PF04082.13 GAO82129.1 - 2.1e-14 53.0 0.0 3.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRKCSH PF07915.8 GAO82130.1 - 5.6e-21 75.1 0.1 5.6e-21 75.1 0.1 3.0 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein DHquinase_II PF01220.14 GAO82130.1 - 0.0023 17.2 0.1 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Dehydroquinase class II PRKCSH_1 PF13015.1 GAO82130.1 - 0.0037 16.7 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein bPH_5 PF10882.3 GAO82130.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain SHD1 PF03983.7 GAO82131.1 - 4.7e-36 122.2 0.0 9e-36 121.3 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 GAO82131.1 - 3.4e-35 119.1 7.3 4e-13 48.5 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 GAO82131.1 - 4.2e-32 109.4 8.0 1.5e-13 50.0 0.5 4.0 4 0 0 4 4 4 3 Variant SH3 domain Pirin PF02678.11 GAO82131.1 - 1.3e-31 108.5 0.1 2.8e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Pirin SH3_2 PF07653.12 GAO82131.1 - 8.4e-23 79.6 0.2 8.4e-09 34.7 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain Pirin_C PF05726.8 GAO82131.1 - 7e-22 77.4 0.0 1.8e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Pirin C-terminal cupin domain SH3_3 PF08239.6 GAO82131.1 - 0.00055 20.0 3.0 0.24 11.6 0.2 3.0 3 0 0 3 3 3 2 Bacterial SH3 domain Cupin_2 PF07883.6 GAO82131.1 - 0.0018 17.7 1.4 0.0018 17.7 0.9 2.3 3 0 0 3 3 3 1 Cupin domain SAM_1 PF00536.25 GAO82131.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Cupin_3 PF05899.7 GAO82131.1 - 0.32 10.4 2.2 8.5 5.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF861) DUF1720 PF08226.6 GAO82131.1 - 0.76 9.8 165.5 2.6e+02 1.7 0.0 7.8 2 1 3 5 5 3 0 Domain of unknown function (DUF1720) PMT PF02366.13 GAO82132.1 - 1e-82 277.2 19.3 2e-82 276.2 13.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAO82132.1 - 2.8e-17 62.8 1.6 5.4e-17 61.9 0.7 1.7 1 1 1 2 2 2 1 MIR domain PMT_2 PF13231.1 GAO82132.1 - 0.0025 17.7 10.9 0.0025 17.7 7.6 3.4 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase AF1Q PF15017.1 GAO82133.1 - 1 9.3 6.5 0.24 11.3 1.8 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator MFS_1 PF07690.11 GAO82134.1 - 4.7e-35 120.9 29.4 4.7e-35 120.9 20.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82134.1 - 6.9e-10 38.0 23.5 9e-10 37.7 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter GlpM PF06942.7 GAO82134.1 - 0.0091 16.2 2.8 0.041 14.1 1.9 2.2 1 0 0 1 1 1 1 GlpM protein WD40 PF00400.27 GAO82135.1 - 3.5e-18 64.7 5.1 2.3e-05 24.0 0.0 5.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 GAO82136.1 - 3.4e-22 78.1 0.3 3.5e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF1762 PF08574.5 GAO82136.1 - 0.083 13.3 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) PCI_Csn8 PF10075.4 GAO82137.1 - 6.2e-35 120.0 0.0 8.3e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAO82137.1 - 1.6e-05 24.5 0.3 1.9e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family STT3 PF02516.9 GAO82138.1 - 1.6e-135 452.7 41.0 7.6e-131 437.4 26.5 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF3453 PF11935.3 GAO82140.1 - 5.1e-78 261.7 0.3 1.5e-77 260.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 GAO82141.1 - 4.7e-25 88.3 4.6 4.7e-25 88.3 3.2 2.6 2 2 0 2 2 2 1 Sds3-like DUF1487 PF07368.6 GAO82141.1 - 0.013 14.7 0.8 1.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.17 GAO82142.1 - 9.4e-09 34.7 0.1 3e-06 26.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82142.1 - 1.9e-08 34.0 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82142.1 - 4.3e-05 23.4 0.1 0.0068 16.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.8 GAO82142.1 - 0.67 9.1 26.0 0.12 11.5 14.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pyr_redox_3 PF13738.1 GAO82144.1 - 3.5e-30 105.6 0.0 5e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO82144.1 - 4.8e-12 46.1 0.0 6.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO82144.1 - 1.1e-05 24.5 0.0 0.0003 19.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAO82144.1 - 2.4e-05 24.1 0.2 0.0032 17.2 0.2 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding GPI-anchored PF10342.4 GAO82145.1 - 1.4e-19 70.3 3.5 1.4e-19 70.3 2.4 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 GAO82145.1 - 0.0004 19.9 2.3 0.00093 18.7 1.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF966 PF06136.8 GAO82145.1 - 0.13 11.6 6.0 0.14 11.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF605 PF04652.11 GAO82145.1 - 1.7 7.9 10.1 1.8 7.8 7.0 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 GAO82145.1 - 4.5 5.8 17.0 4.8 5.7 11.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 GAO82145.1 - 6.4 4.9 13.4 7.8 4.6 9.3 1.0 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 GAO82145.1 - 7.3 6.1 15.6 8.7 5.9 10.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 NUFIP1 PF10453.4 GAO82146.1 - 2.3e-18 65.4 3.2 2.3e-18 65.4 2.2 2.9 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 GAO82146.1 - 2.1e-06 27.2 4.5 3.4e-06 26.5 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.7 GAO82147.1 - 3.4e-37 127.3 0.0 4.8e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 GAO82147.1 - 5.2e-15 55.3 0.0 8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 GAO82148.1 - 7.2e-139 462.3 0.1 8.2e-139 462.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAO82148.1 - 7.3e-09 35.0 0.2 1.3e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO82148.1 - 1.3e-06 27.6 0.5 2.5e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAO82148.1 - 2.1e-06 26.7 0.4 4.4e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO82148.1 - 0.00039 19.6 0.1 0.00068 18.8 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Methyltransf_16 PF10294.4 GAO82149.1 - 0.006 16.0 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Filament PF00038.16 GAO82151.1 - 0.00034 20.2 66.8 0.023 14.1 38.5 2.6 1 1 1 2 2 2 2 Intermediate filament protein Fez1 PF06818.10 GAO82151.1 - 0.0047 16.9 21.8 0.0047 16.9 15.1 3.1 1 1 1 2 2 2 1 Fez1 DUF3584 PF12128.3 GAO82151.1 - 0.0066 13.8 69.5 0.12 9.7 12.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 GAO82151.1 - 0.096 11.8 18.3 0.37 9.9 3.7 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein VirB3 PF05101.8 GAO82151.1 - 0.27 11.2 0.3 0.47 10.4 0.2 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein TPR_MLP1_2 PF07926.7 GAO82151.1 - 0.47 10.1 81.1 0.035 13.8 14.5 4.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.21 GAO82152.1 - 0.00097 19.3 30.4 0.38 11.1 1.0 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO82153.1 - 0.0056 16.9 42.1 0.096 13.0 0.3 7.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO82153.1 - 0.59 10.3 14.1 0.44 10.7 1.5 4.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AAA PF00004.24 GAO82155.1 - 2.8e-49 166.7 0.0 1.9e-42 144.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAO82155.1 - 7.1e-08 32.0 0.0 4.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAO82155.1 - 1.9e-06 27.9 0.0 3.6e-05 23.8 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAO82155.1 - 4.8e-06 26.7 0.0 0.00092 19.3 0.0 3.8 3 1 0 3 3 2 1 AAA domain AAA_2 PF07724.9 GAO82155.1 - 5.2e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 GAO82155.1 - 4.3e-05 23.3 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 GAO82155.1 - 0.00017 21.3 0.0 0.00086 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 GAO82155.1 - 0.00018 21.5 0.0 0.067 13.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 GAO82155.1 - 0.0014 19.4 0.5 0.011 16.5 0.0 2.9 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.1 GAO82155.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO82155.1 - 0.0028 17.1 0.0 0.0098 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 GAO82155.1 - 0.0038 17.3 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 GAO82155.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO82155.1 - 0.0084 15.8 4.8 0.023 14.4 0.0 3.3 4 0 0 4 4 2 1 Part of AAA domain AAA_18 PF13238.1 GAO82155.1 - 0.011 16.0 0.0 0.056 13.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAO82155.1 - 0.012 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 GAO82155.1 - 0.014 15.0 0.0 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 GAO82155.1 - 0.026 13.5 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAO82155.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAO82155.1 - 0.039 13.4 0.0 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 GAO82155.1 - 0.04 13.5 0.1 0.18 11.4 0.0 2.2 2 1 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 GAO82155.1 - 0.042 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 GAO82155.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 GAO82155.1 - 0.072 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 GAO82155.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 GAO82155.1 - 0.093 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 GAO82155.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAO82155.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein QRPTase_C PF01729.14 GAO82155.1 - 0.15 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Torsin PF06309.6 GAO82155.1 - 0.25 11.2 0.0 0.51 10.2 0.0 1.4 1 0 0 1 1 1 0 Torsin PIF1 PF05970.9 GAO82155.1 - 0.51 9.2 0.0 0.85 8.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sec66 PF09802.4 GAO82156.1 - 3.2e-84 281.0 0.3 3.8e-84 280.8 0.2 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3440 PF11922.3 GAO82156.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) DUF3848 PF12959.2 GAO82156.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Duffy_binding PF05424.6 GAO82156.1 - 0.065 13.0 2.6 0.15 11.9 1.8 1.6 1 1 0 1 1 1 0 Duffy binding domain DUF964 PF06133.6 GAO82156.1 - 0.31 11.0 3.4 0.4 10.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF964) Rabaptin PF03528.10 GAO82156.1 - 0.36 10.7 3.7 2.3 8.1 0.2 2.3 2 0 0 2 2 2 0 Rabaptin PPR_2 PF13041.1 GAO82157.1 - 4e-10 39.4 0.5 0.028 14.3 0.0 5.8 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 GAO82157.1 - 2.3e-07 30.5 1.5 0.98 9.8 0.0 6.3 8 0 0 8 8 8 2 Pentatricopeptide repeat domain Enkurin PF13864.1 GAO82157.1 - 0.0058 16.8 2.1 2.3 8.4 0.3 3.0 2 0 0 2 2 2 2 Calmodulin-binding PPR PF01535.15 GAO82157.1 - 0.6 10.2 8.8 1.7 8.8 0.0 4.1 5 0 0 5 5 5 0 PPR repeat ORC3_N PF07034.6 GAO82158.1 - 2.4e-31 108.9 0.0 2.8e-30 105.4 0.0 2.4 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus HEAT_2 PF13646.1 GAO82159.1 - 0.023 14.9 0.5 0.064 13.5 0.4 1.7 1 0 0 1 1 1 0 HEAT repeats Nop14 PF04147.7 GAO82160.1 - 4.9e-302 1003.9 28.3 5.7e-302 1003.7 19.6 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 GAO82160.1 - 0.11 11.3 0.1 0.25 10.1 0.0 1.5 1 0 0 1 1 1 0 Noc2p family COesterase PF00135.23 GAO82161.1 - 1.2e-94 317.9 0.3 1.6e-94 317.5 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO82161.1 - 2.9e-08 33.5 0.1 1.6e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO82161.1 - 0.006 16.3 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO82161.1 - 0.038 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4187 PF13821.1 GAO82162.1 - 2.4e-18 65.4 3.0 9.3e-18 63.5 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 GAO82162.1 - 6e-08 32.3 2.2 6.1e-07 29.1 1.5 2.2 1 1 0 1 1 1 1 G-patch domain Peptidase_S49_N PF08496.5 GAO82164.1 - 0.097 12.4 8.7 0.41 10.4 3.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DbpA PF03880.10 GAO82165.1 - 0.02 14.5 1.2 0.034 13.8 0.0 2.1 3 0 0 3 3 3 0 DbpA RNA binding domain MFS_1 PF07690.11 GAO82166.1 - 3.5e-30 104.9 34.6 3.8e-27 94.9 7.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82166.1 - 3.6e-11 42.2 2.2 3.6e-11 42.2 1.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 GAO82166.1 - 5.4 4.9 12.8 0.31 9.1 1.1 2.9 2 2 0 3 3 3 0 Transmembrane secretion effector Kinetocho_Slk19 PF12709.2 GAO82167.1 - 5.4e-27 93.6 26.4 5.8e-25 87.1 4.3 4.3 4 1 0 4 4 4 2 Central kinetochore-associated DUF208 PF02677.9 GAO82167.1 - 0.0075 16.0 6.1 0.014 15.1 4.3 1.4 1 0 0 1 1 1 1 Uncharacterized BCR, COG1636 Herpes_U30 PF04523.8 GAO82167.1 - 0.1 10.0 6.6 0.17 9.3 4.6 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 PV-1 PF06637.6 GAO82167.1 - 3.3 6.1 33.9 0.86 8.0 12.8 3.1 1 1 1 2 2 2 0 PV-1 protein (PLVAP) ADIP PF11559.3 GAO82167.1 - 7.6 6.4 31.4 5.5 6.8 1.2 4.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 GAO82167.1 - 9.5 6.2 8.7 1.2 9.1 0.2 3.2 2 1 1 3 3 3 0 FlxA-like protein Fungal_trans PF04082.13 GAO82168.1 - 6.2e-35 120.3 0.8 9.3e-35 119.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Toxin_62 PF15540.1 GAO82168.1 - 0.086 12.9 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 62 Peptidase_S10 PF00450.17 GAO82169.1 - 2.5e-113 379.4 0.8 2.9e-113 379.1 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 GAO82170.1 - 1.4e-13 50.3 33.8 2e-13 49.7 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAO82170.1 - 3.2e-10 39.7 5.2 3.2e-10 39.7 3.6 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Amidohydro_1 PF01979.15 GAO82171.1 - 6.3e-16 58.9 0.0 1.8e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO82171.1 - 1.4e-13 51.4 1.4 6.6e-13 49.3 1.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAO82171.1 - 7.4e-07 28.7 0.0 3.3e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAO82171.1 - 1.9e-05 24.3 0.0 5.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase GMC_oxred_N PF00732.14 GAO82172.1 - 6.5e-53 179.7 0.0 8.3e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO82172.1 - 4.6e-39 133.9 0.0 7.1e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAO82172.1 - 1.4e-06 27.4 0.1 0.00062 18.7 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO82172.1 - 1.7e-06 27.1 0.1 0.028 13.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO82172.1 - 5.7e-05 23.0 0.2 0.00021 21.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAO82172.1 - 0.00029 19.8 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 GAO82172.1 - 0.0028 16.7 0.2 0.04 13.0 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO82172.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO82172.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 GAO82172.1 - 0.097 12.7 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO82172.1 - 0.12 11.2 0.2 4.4 6.0 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAO82172.1 - 0.13 12.7 0.2 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 GAO82173.1 - 1e-156 521.8 0.0 1.2e-156 521.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 GAO82174.1 - 6.8e-16 58.5 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 GAO82175.1 - 5.9e-56 189.6 0.0 7.6e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 GAO82175.1 - 0.00012 21.9 0.0 0.00063 19.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 GAO82175.1 - 0.00042 19.9 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 GAO82175.1 - 0.028 14.5 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 GAO82175.1 - 0.065 13.1 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 GAO82176.1 - 2.1e-37 128.9 0.1 8e-37 127.0 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family CPSF_A PF03178.10 GAO82177.1 - 3.8e-101 338.3 0.0 1.1e-100 336.8 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 GAO82177.1 - 1.7e-08 33.0 0.0 0.00018 19.7 0.0 2.4 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 GAO82178.1 - 3.3e-07 29.2 9.3 1.6e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein UPF0233 PF06781.7 GAO82178.1 - 8 6.1 6.9 2 8.0 0.1 3.3 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) Zip PF02535.17 GAO82179.1 - 1e-30 106.8 0.3 1.4e-30 106.4 0.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Thiolase_N PF00108.18 GAO82180.1 - 1.3e-85 286.5 0.2 2e-85 285.9 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO82180.1 - 7.1e-45 151.4 2.1 1.4e-44 150.4 1.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAO82180.1 - 2.1e-06 27.4 0.3 5.9e-06 25.9 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAO82180.1 - 0.0086 15.7 2.3 0.24 11.0 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 GAO82181.1 - 4.4e-44 150.1 0.0 6.4e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAO82181.1 - 2.5e-27 94.8 0.0 7.6e-27 93.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 GAO82181.1 - 2.8e-19 68.7 0.0 7.3e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO82181.1 - 1.8e-08 34.3 0.0 4.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAO82181.1 - 3.6e-07 29.9 0.1 2.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAO82181.1 - 1.6e-05 24.8 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO82181.1 - 0.00017 22.0 0.1 0.00046 20.6 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAO82181.1 - 0.003 16.7 0.4 0.061 12.5 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 GAO82181.1 - 0.049 13.4 0.1 10 5.9 0.1 2.6 1 1 1 2 2 2 0 Dynamin family Ras PF00071.17 GAO82181.1 - 0.062 12.6 0.1 0.29 10.5 0.0 2.1 1 1 0 1 1 1 0 Ras family DUF59 PF01883.14 GAO82182.1 - 1.4e-06 28.1 0.0 3.8e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 GAO82183.1 - 1.1e-08 34.3 0.3 2.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain APC_CDC26 PF10471.4 GAO82184.1 - 1e-21 77.4 0.7 1.1e-21 77.2 0.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 PELOTA_1 PF15608.1 GAO82184.1 - 0.034 13.9 0.3 4.9 6.9 0.1 2.0 1 1 1 2 2 2 0 PELOTA RNA binding domain Mcm10 PF09332.6 GAO82185.1 - 1 8.6 5.0 6.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Mcm10 replication factor HSP70 PF00012.15 GAO82186.1 - 8e-233 773.7 7.8 8e-233 773.7 5.4 1.8 2 0 0 2 2 2 1 Hsp70 protein RRF PF01765.14 GAO82186.1 - 2.6e-37 127.8 0.7 2.6e-37 127.8 0.5 2.2 2 0 0 2 2 2 1 Ribosome recycling factor MreB_Mbl PF06723.8 GAO82186.1 - 5.4e-17 61.3 0.1 4.7e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAO82186.1 - 0.00083 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MRC1 PF09444.5 GAO82186.1 - 1.8 8.8 10.0 0.073 13.3 1.1 2.5 2 0 0 2 2 2 0 MRC1-like domain zf-RING_2 PF13639.1 GAO82188.1 - 7.7e-14 51.2 6.4 1.4e-13 50.4 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO82188.1 - 3.4e-08 33.4 2.7 9.1e-08 32.0 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAO82188.1 - 4.7e-08 32.5 4.0 4.7e-08 32.5 2.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO82188.1 - 3.2e-06 26.7 5.0 3.6e-06 26.5 2.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAO82188.1 - 3.4e-06 26.9 5.5 6.8e-06 26.0 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO82188.1 - 2.2e-05 24.0 2.5 4.7e-05 22.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAO82188.1 - 0.0035 17.1 3.4 0.0099 15.6 2.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAO82188.1 - 0.013 15.0 5.9 0.022 14.3 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 GAO82188.1 - 0.032 13.9 5.6 0.06 13.0 3.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 GAO82188.1 - 0.13 12.1 4.8 0.38 10.6 3.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 GAO82188.1 - 0.18 11.8 5.6 0.38 10.8 3.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 GAO82188.1 - 0.38 10.7 3.9 1.1 9.2 2.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 GAO82188.1 - 4.6 7.0 8.0 0.47 10.2 1.0 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 tRNA-synt_2c PF01411.14 GAO82189.1 - 3.2e-216 718.9 0.0 4.5e-216 718.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAO82189.1 - 4.3e-17 61.7 0.6 1e-16 60.5 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAO82189.1 - 0.0015 18.1 1.9 0.0045 16.6 1.3 1.9 1 0 0 1 1 1 1 DHHA1 domain Ribosomal_S3Ae PF01015.13 GAO82190.1 - 5.9e-80 267.1 5.0 8.4e-80 266.6 3.5 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family UPRTase PF14681.1 GAO82190.1 - 1.1e-66 224.0 0.0 1.8e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAO82190.1 - 0.00017 21.2 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 GAO82190.1 - 0.13 12.0 0.3 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 GAO82191.1 - 5.6e-92 308.2 1.2 7.9e-92 307.7 0.8 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 GAO82191.1 - 2.3e-40 137.6 0.2 4.1e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO82191.1 - 2.7e-10 40.7 0.0 5.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO82191.1 - 7.9e-08 31.7 0.0 1.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO82191.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAO82191.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_2b PF00587.20 GAO82192.1 - 1.1e-33 116.3 0.0 1.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAO82192.1 - 1.1e-18 67.2 5.7 1.1e-18 67.2 3.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 GAO82192.1 - 0.0062 16.2 3.6 0.0062 16.2 2.5 2.1 2 0 0 2 2 2 1 Mnd1 family DUF4375 PF14300.1 GAO82192.1 - 0.27 11.2 5.6 0.29 11.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) IFT57 PF10498.4 GAO82192.1 - 0.34 9.6 8.5 0.17 10.6 2.5 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Atg14 PF10186.4 GAO82192.1 - 0.78 8.6 5.5 4.1 6.2 4.2 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 GAO82192.1 - 4.4 7.1 7.3 9.8 5.9 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-Hacid_dh_C PF02826.14 GAO82193.1 - 6.3e-51 172.0 0.0 9.3e-51 171.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO82193.1 - 1.3e-34 118.5 0.0 1.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAO82193.1 - 5e-05 23.1 0.1 0.00013 21.8 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 GAO82193.1 - 0.00059 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 GAO82193.1 - 0.0096 15.3 0.0 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain 3HCDH_N PF02737.13 GAO82193.1 - 0.04 13.5 0.9 1.2 8.7 0.3 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAD PF12710.2 GAO82194.1 - 4e-32 111.9 0.0 2.4e-31 109.4 0.0 2.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAO82194.1 - 3.2e-31 108.1 0.3 3.5e-30 104.7 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Pkinase PF00069.20 GAO82194.1 - 7.6e-28 97.3 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Hydrolase PF00702.21 GAO82194.1 - 3.9e-18 66.6 0.0 5.3e-17 62.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 GAO82194.1 - 3.1e-08 33.5 1.1 4.2e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter Pkinase_Tyr PF07714.12 GAO82194.1 - 9.1e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cation_ATPase_N PF00690.21 GAO82194.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAO82194.1 - 0.0066 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO82194.1 - 0.033 13.7 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Myosin_head PF00063.16 GAO82195.1 - 4e-227 755.5 11.5 5.4e-214 712.1 1.9 2.6 2 1 1 3 3 3 2 Myosin head (motor domain) NAP PF00956.13 GAO82195.1 - 1.4e-85 286.3 11.6 1.4e-85 286.3 8.0 3.3 3 1 0 3 3 1 1 Nucleosome assembly protein (NAP) DIL PF01843.14 GAO82195.1 - 1.1e-34 118.4 3.4 3.5e-34 116.8 2.3 2.0 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.1 GAO82195.1 - 0.00068 19.7 1.0 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAO82195.1 - 0.0019 17.4 0.0 0.0058 15.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 TMP_2 PF06791.8 GAO82195.1 - 0.0019 17.8 3.4 0.0039 16.8 1.7 1.9 1 1 1 2 2 2 1 Prophage tail length tape measure protein AAA_16 PF13191.1 GAO82195.1 - 0.015 15.2 3.4 0.097 12.6 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 GAO82195.1 - 0.021 14.5 0.0 0.069 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain IQ PF00612.22 GAO82195.1 - 0.13 11.9 17.4 0.12 12.0 1.5 3.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 GAO82195.1 - 0.32 10.1 2.9 0.67 9.0 2.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 GAO82195.1 - 0.51 9.4 39.8 0.0057 15.8 10.3 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2457 PF10446.4 GAO82195.1 - 4 6.0 35.6 1.4 7.5 13.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Fib_alpha PF08702.5 GAO82195.1 - 4.7 7.3 14.8 2.2 8.4 7.2 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.7 GAO82195.1 - 6 5.1 8.1 10 4.4 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ham1p_like PF01725.11 GAO82196.1 - 1.1e-52 178.1 0.0 1.3e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.8 GAO82197.1 - 5.8e-73 244.6 0.0 7.3e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 AA_kinase PF00696.23 GAO82198.1 - 4.4e-37 127.9 0.0 9.8e-37 126.7 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 GAO82198.1 - 7.6e-12 44.5 1.0 6.5e-10 38.3 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 GAO82198.1 - 3.4e-11 42.3 2.2 1.9e-09 36.8 0.1 2.9 3 1 0 3 3 3 2 ACT domain Fork_head PF00250.13 GAO82199.1 - 1.4e-36 124.3 0.1 2.6e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Ribosomal_L23eN PF03939.8 GAO82200.1 - 4.9e-23 80.9 7.8 1.1e-22 79.7 5.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 GAO82200.1 - 1.7e-17 63.1 1.5 3.4e-17 62.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3321 PF11968.3 GAO82201.1 - 2.2e-93 311.9 0.0 2.6e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 GAO82201.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aa_trans PF01490.13 GAO82202.1 - 2.9e-70 236.8 23.2 3.4e-70 236.5 16.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.10 GAO82203.1 - 1.7e-47 161.0 0.2 2.9e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAO82203.1 - 2.9e-39 133.8 0.9 5.8e-39 132.8 0.6 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 GAO82203.1 - 3.4e-28 97.8 0.0 6.1e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 GAO82203.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family VanY PF02557.12 GAO82203.1 - 0.12 12.2 0.2 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PDT PF00800.13 GAO82204.1 - 2.8e-68 229.0 0.1 3.9e-68 228.5 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 GAO82204.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain DER1 PF04511.10 GAO82205.1 - 2.2e-30 105.6 5.7 2.5e-30 105.4 3.9 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 GAO82205.1 - 5.3 7.0 14.4 0.83 9.6 7.1 1.8 2 1 0 2 2 2 0 Rhomboid family DKCLD PF08068.7 GAO82206.1 - 5.8e-30 103.0 1.5 3.4e-29 100.5 0.0 2.8 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 GAO82206.1 - 1.6e-24 86.7 0.1 1.1e-21 77.6 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 GAO82206.1 - 2.7e-21 75.0 1.6 5.2e-21 74.1 1.1 1.5 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 GAO82206.1 - 4.6 6.8 21.3 8.2 6.0 14.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.4 GAO82207.1 - 2e-36 124.8 1.1 2.9e-36 124.3 0.1 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAO82207.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 LisH V_ATPase_I PF01496.14 GAO82207.1 - 0.46 8.2 3.7 0.6 7.9 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2431 PF10354.4 GAO82208.1 - 2.3e-44 151.2 0.0 1.3e-32 113.0 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF2431) Uds1 PF15456.1 GAO82208.1 - 4.8 7.2 7.8 0.26 11.3 1.5 1.8 2 0 0 2 2 2 0 Up-regulated During Septation U1snRNP70_N PF12220.3 GAO82208.1 - 7.9 6.8 9.1 3.1 8.1 2.9 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UAA PF08449.6 GAO82209.1 - 2e-12 46.6 19.7 2.6e-12 46.2 13.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAO82209.1 - 5.6e-10 39.0 6.3 5.6e-10 39.0 4.3 2.6 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 GAO82209.1 - 0.00087 19.3 7.5 0.00087 19.3 5.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 GAO82209.1 - 0.0067 15.1 3.9 0.0067 15.1 2.7 2.5 2 1 0 2 2 2 1 Phosphate transporter family Thioredoxin PF00085.15 GAO82210.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin SMI1_KNR4 PF09346.5 GAO82211.1 - 1.8e-36 125.0 0.0 4.1e-36 123.8 0.0 1.6 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.1 GAO82212.1 - 2.1e-07 30.8 3.0 2.1e-07 30.8 2.1 5.0 6 0 0 6 6 6 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 GAO82213.1 - 8.4e-36 121.9 13.5 1.1e-35 121.6 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAO82213.1 - 1.7e-17 63.0 10.3 2.2e-17 62.6 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 GAO82213.1 - 3.3e-07 30.0 12.6 2e-06 27.4 8.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAO82213.1 - 0.0013 18.3 11.9 0.023 14.3 8.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO82213.1 - 0.0031 17.1 9.5 0.29 10.8 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO82213.1 - 0.049 13.6 13.1 0.051 13.6 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAO82213.1 - 0.17 11.8 9.3 0.81 9.6 6.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 GAO82213.1 - 0.32 11.1 10.2 21 5.3 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 GAO82213.1 - 0.55 9.9 6.7 1.2 8.8 2.2 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 GAO82213.1 - 0.57 10.1 9.6 1.4 8.9 6.6 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 GAO82213.1 - 1.1 9.0 11.8 7.9 6.2 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain GHMP_kinases_N PF00288.21 GAO82214.1 - 7.7e-10 38.7 0.1 1.2e-08 34.8 0.1 2.4 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAO82214.1 - 2.7e-05 24.2 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Mid1 PF12929.2 GAO82215.1 - 2.3e-151 504.3 1.4 3.4e-151 503.7 1.0 1.3 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component CorA PF01544.13 GAO82215.1 - 4.5e-42 144.0 0.0 7.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein A_thal_3526 PF09713.5 GAO82215.1 - 0.031 14.4 0.1 0.078 13.1 0.1 1.7 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Es2 PF09751.4 GAO82216.1 - 3.2e-118 395.7 6.4 3.8e-118 395.5 4.4 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 TPR_2 PF07719.12 GAO82218.1 - 6e-28 94.4 33.7 0.00051 19.7 0.1 11.9 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 GAO82218.1 - 2.6e-24 83.7 23.6 0.0001 21.7 0.0 10.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAO82218.1 - 4.6e-24 83.8 40.1 1.4e-06 27.8 0.9 10.8 9 3 4 13 13 13 7 TPR repeat TPR_19 PF14559.1 GAO82218.1 - 1.7e-20 73.1 23.5 0.00056 20.1 0.0 9.1 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82218.1 - 1.4e-16 58.9 27.7 0.00012 21.5 0.0 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAO82218.1 - 1.2e-13 50.3 46.2 0.0093 16.5 0.1 12.2 11 2 2 13 13 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAO82218.1 - 1.9e-13 50.1 42.0 6.7e-05 22.7 0.7 9.6 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAO82218.1 - 2.9e-11 43.7 50.1 0.0016 19.0 0.0 11.2 10 1 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO82218.1 - 1.1e-08 34.5 15.9 0.6 10.4 0.0 10.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO82218.1 - 9.1e-07 28.9 38.1 0.078 13.4 0.1 11.3 14 0 0 14 14 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAO82218.1 - 5.2e-05 22.7 35.1 0.00055 19.5 0.3 9.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAO82218.1 - 0.013 15.4 25.2 0.21 11.5 0.2 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat Acyltransferase PF01553.16 GAO82219.1 - 5.4e-27 93.8 0.0 1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 GAO82220.1 - 5.4e-34 117.2 0.0 7.7e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.20 GAO82221.1 - 3.6e-69 232.8 0.0 6.3e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82221.1 - 1.1e-51 175.4 0.0 1.8e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAO82221.1 - 1.2e-23 83.2 0.3 7.6e-23 80.7 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 GAO82221.1 - 7.9e-22 77.6 0.3 3e-21 75.7 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 GAO82221.1 - 1.2e-07 31.9 0.1 2.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 GAO82221.1 - 8.8e-07 28.1 0.0 1.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO82221.1 - 0.033 13.9 0.3 0.033 13.9 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO82221.1 - 0.084 11.6 0.1 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_2b PF00587.20 GAO82223.1 - 3.1e-68 228.7 0.2 5.3e-68 227.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAO82223.1 - 4.3e-22 77.8 5.1 6.3e-22 77.3 0.0 3.4 3 1 0 3 3 3 1 Anticodon binding domain Brix PF04427.13 GAO82224.1 - 6.6e-39 133.5 0.1 9.6e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain AMPKBI PF04739.10 GAO82224.1 - 0.66 9.8 2.7 1.4 8.8 0.5 2.1 1 1 1 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Nop14 PF04147.7 GAO82224.1 - 0.66 7.8 21.1 0.89 7.3 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAO82224.1 - 1.7 6.5 13.2 2.4 6.0 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pept_tRNA_hydro PF01195.14 GAO82225.1 - 1.5e-20 73.4 0.0 1.6e-05 24.4 0.0 3.5 2 2 1 3 3 3 3 Peptidyl-tRNA hydrolase BAR PF03114.13 GAO82226.1 - 3.8e-63 213.0 5.0 4.7e-63 212.7 3.5 1.1 1 0 0 1 1 1 1 BAR domain DUF3987 PF13148.1 GAO82226.1 - 0.35 9.3 4.0 0.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FliD_N PF02465.13 GAO82226.1 - 0.59 10.5 2.6 6.4 7.2 0.4 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.20 GAO82227.1 - 4.1e-62 209.6 0.0 6.7e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82227.1 - 1.5e-26 93.0 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAO82227.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAO82227.1 - 0.01 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAO82227.1 - 0.028 14.1 0.9 1.9 8.1 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Apt1 PF10351.4 GAO82227.1 - 5.8 5.6 6.4 8.8 5.0 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sybindin PF04099.7 GAO82228.1 - 1.1e-26 93.2 0.0 1.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAO82228.1 - 0.00046 20.0 0.1 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 GAO82229.1 - 3e-60 203.5 0.0 5.1e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82229.1 - 2.3e-35 121.9 0.0 3.2e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO82229.1 - 8.8e-10 38.0 0.0 1.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAO82229.1 - 0.02 14.6 0.1 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AT_hook PF02178.14 GAO82230.1 - 0.0061 16.0 1.5 0.045 13.4 1.1 2.7 1 0 0 1 1 1 1 AT hook motif SRI PF08236.6 GAO82231.1 - 1.1e-22 79.7 13.3 3e-22 78.3 9.2 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 GAO82231.1 - 3.3e-22 79.5 0.2 3.3e-22 79.5 0.1 4.0 2 2 0 2 2 2 1 SET domain DUF3287 PF11690.3 GAO82231.1 - 0.0048 16.9 1.2 0.0048 16.9 0.8 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3287) WW PF00397.21 GAO82231.1 - 0.0091 15.8 1.0 0.0091 15.8 0.7 2.7 3 0 0 3 3 3 1 WW domain Pox_H7 PF04787.7 GAO82231.1 - 0.056 13.2 2.1 0.17 11.6 1.4 1.8 1 0 0 1 1 1 0 Late protein H7 eIF-6 PF01912.13 GAO82232.1 - 8.3e-84 279.6 0.4 1.1e-83 279.2 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family FA PF08736.6 GAO82234.1 - 0.014 15.1 0.4 0.064 13.0 0.3 2.1 1 0 0 1 1 1 0 FERM adjacent (FA) DUF3353 PF11833.3 GAO82234.1 - 4.2 6.7 9.2 1.1 8.7 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) XPC-binding PF09280.6 GAO82235.1 - 5.5e-23 80.1 13.9 1.2e-22 79.1 9.6 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 GAO82235.1 - 5.6e-20 70.5 0.9 8.6e-20 69.9 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAO82235.1 - 2.1e-19 68.7 0.2 1.6e-09 37.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 GAO82235.1 - 6.9e-08 32.0 0.7 1.1e-07 31.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAO82235.1 - 0.00027 20.7 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 GAO82235.1 - 0.0048 16.7 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain UBA_3 PF09288.5 GAO82235.1 - 0.015 14.9 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2407 PF10302.4 GAO82235.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain CUE PF02845.11 GAO82235.1 - 0.084 12.3 0.0 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 CUE domain Glyco_transf_22 PF03901.12 GAO82236.1 - 8.1e-65 219.4 20.7 1.1e-64 219.0 14.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4383 PF14325.1 GAO82236.1 - 0.82 9.6 5.9 0.35 10.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Skp1 PF01466.14 GAO82237.1 - 9.3e-40 134.5 2.2 1.4e-39 133.9 1.6 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAO82237.1 - 1.1e-23 83.0 0.4 2.3e-23 82.0 0.2 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC_membrane PF00664.18 GAO82238.1 - 1.6e-96 322.9 37.6 2e-50 171.7 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO82238.1 - 4e-65 218.2 0.0 4.7e-32 111.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAO82238.1 - 9.7e-14 51.1 1.4 0.00031 20.0 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO82238.1 - 5e-11 43.0 0.2 0.23 11.4 0.0 4.4 2 2 0 4 4 4 4 AAA domain AAA_29 PF13555.1 GAO82238.1 - 1.5e-08 34.0 0.7 0.00049 19.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO82238.1 - 1.7e-08 34.6 0.6 0.0013 18.7 0.0 3.6 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 GAO82238.1 - 2.7e-08 34.6 0.1 0.0073 17.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain ABC_ATPase PF09818.4 GAO82238.1 - 3.9e-08 32.3 3.4 0.00099 17.7 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAO82238.1 - 4.5e-07 29.1 0.1 0.084 12.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO82238.1 - 5.1e-06 26.0 0.2 0.12 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 GAO82238.1 - 1.2e-05 25.4 2.3 8.7 6.5 0.0 4.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO82238.1 - 1.7e-05 25.0 2.4 0.17 12.0 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAO82238.1 - 8.9e-05 22.0 2.3 1.3 8.3 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 GAO82238.1 - 0.00042 20.2 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO82238.1 - 0.00074 19.8 0.1 0.92 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAO82238.1 - 0.0021 17.7 1.5 2.9 7.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 GAO82238.1 - 0.0026 17.4 0.9 0.99 9.1 0.2 3.0 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 GAO82238.1 - 0.0027 17.5 5.6 1 9.3 0.3 3.9 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 GAO82238.1 - 0.0044 15.7 0.1 0.074 11.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 GAO82238.1 - 0.0048 16.3 0.5 0.72 9.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 GAO82238.1 - 0.0051 16.4 7.6 2.3 7.7 0.0 4.4 5 0 0 5 5 5 1 AAA domain AAA_14 PF13173.1 GAO82238.1 - 0.0063 16.4 0.2 0.82 9.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 GAO82238.1 - 0.0072 16.0 0.5 5.9 6.5 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 GAO82238.1 - 0.0091 16.1 0.3 3.5 7.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.1 GAO82238.1 - 0.011 16.0 0.3 5.4 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 GAO82238.1 - 0.017 15.0 0.5 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAO82238.1 - 0.13 11.8 0.7 8 6.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Swi5 PF07061.6 GAO82239.1 - 6e-36 122.0 0.4 9.6e-36 121.4 0.1 1.4 1 1 0 1 1 1 1 Swi5 DUF812 PF05667.6 GAO82239.1 - 0.0077 14.7 0.7 0.0084 14.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3373 PF11853.3 GAO82239.1 - 0.011 14.3 0.5 0.011 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4200 PF13863.1 GAO82239.1 - 0.017 15.0 4.4 0.026 14.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 GAO82239.1 - 0.017 15.1 1.1 0.021 14.8 0.8 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DivIC PF04977.10 GAO82239.1 - 0.021 14.3 2.7 0.033 13.6 1.6 1.5 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 GAO82239.1 - 0.023 14.5 0.8 0.03 14.1 0.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain ALIX_LYPXL_bnd PF13949.1 GAO82239.1 - 0.024 13.6 0.3 0.03 13.2 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TMF_DNA_bd PF12329.3 GAO82239.1 - 0.03 14.1 2.1 0.05 13.4 1.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 GAO82239.1 - 0.038 13.6 0.4 0.045 13.4 0.3 1.1 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 GAO82239.1 - 0.04 13.8 3.3 0.05 13.4 2.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DASH_Spc34 PF08657.5 GAO82239.1 - 0.05 13.2 0.8 0.092 12.3 0.6 1.4 1 1 0 1 1 1 0 DASH complex subunit Spc34 Filament PF00038.16 GAO82239.1 - 0.054 12.9 2.1 0.065 12.7 1.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein Occludin_ELL PF07303.8 GAO82239.1 - 0.1 13.3 0.4 0.14 12.8 0.3 1.3 1 0 0 1 1 1 0 Occludin homology domain Fib_alpha PF08702.5 GAO82239.1 - 0.12 12.5 1.0 0.15 12.2 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 GAO82239.1 - 0.14 11.0 3.8 0.17 10.7 2.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 GAO82239.1 - 0.18 12.2 1.9 0.29 11.5 1.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TcdB_N PF12918.2 GAO82239.1 - 0.22 11.6 1.5 2 8.5 0.1 2.3 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain Mito_fiss_reg PF05308.6 GAO82239.1 - 0.24 10.7 1.6 0.27 10.5 1.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Seryl_tRNA_N PF02403.17 GAO82239.1 - 0.31 11.0 3.0 0.43 10.6 1.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FERM_M PF00373.13 GAO82239.1 - 0.34 11.1 1.5 0.62 10.2 0.8 1.6 2 0 0 2 2 2 0 FERM central domain Ytp1 PF10355.4 GAO82240.1 - 1.7e-87 293.0 15.7 1.7e-87 293.0 10.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAO82240.1 - 1.1e-32 111.6 2.7 1.1e-32 111.6 1.9 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) PIRT PF15099.1 GAO82240.1 - 0.55 9.4 4.3 16 4.7 0.0 3.5 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family ThiF PF00899.16 GAO82241.1 - 6.5e-19 68.0 0.0 1.3e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 ThiF family DUF4407 PF14362.1 GAO82242.1 - 0.31 9.9 4.7 0.1 11.5 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.10 GAO82243.1 - 2.9e-29 101.0 0.2 8.2e-29 99.5 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain CoA_binding PF02629.14 GAO82243.1 - 3.1e-24 85.2 4.5 4.1e-24 84.9 0.9 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAO82243.1 - 2e-21 76.2 0.3 3.2e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAO82243.1 - 2.7e-06 27.0 0.0 5.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Radical_SAM PF04055.16 GAO82244.1 - 1.3e-18 67.7 0.1 3.6e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 GAO82244.1 - 1.1e-12 47.8 0.0 3.1e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO82244.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MARVEL PF01284.18 GAO82245.1 - 0.0072 16.1 1.8 0.0083 15.9 1.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 GAO82245.1 - 0.017 13.8 0.3 0.019 13.6 0.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4013 PF13197.1 GAO82245.1 - 0.031 13.5 0.3 0.037 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) MIG-14_Wnt-bd PF06664.7 GAO82245.1 - 0.045 12.5 0.2 0.052 12.3 0.1 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Yip1 PF04893.12 GAO82245.1 - 0.058 12.9 0.3 0.07 12.6 0.2 1.2 1 0 0 1 1 1 0 Yip1 domain DUF4064 PF13273.1 GAO82245.1 - 0.06 13.4 0.1 0.087 12.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.16 GAO82245.1 - 0.076 12.1 0.2 0.09 11.9 0.1 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) VIT1 PF01988.14 GAO82245.1 - 2.3 7.6 5.3 7.3 6.0 3.6 1.7 1 1 0 1 1 1 0 VIT family Col_cuticle_N PF01484.12 GAO82245.1 - 9.9 5.9 11.6 5.5 6.7 1.5 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain His_biosynth PF00977.16 GAO82246.1 - 9e-33 113.4 0.0 1.1e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.6 GAO82246.1 - 0.14 12.1 0.7 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Ribul_P_3_epim PF00834.14 GAO82246.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Glyco_transf_9 PF01075.12 GAO82246.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) DUF4602 PF15375.1 GAO82247.1 - 1.5e-05 25.1 12.4 1.5e-05 25.1 8.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Amidinotransf PF02274.12 GAO82247.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Mso1_Sec1_bdg PF14475.1 GAO82247.1 - 0.22 10.9 1.3 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 RXT2_N PF08595.6 GAO82247.1 - 5.2 6.8 9.8 0.56 10.0 3.2 2.1 1 1 2 3 3 3 0 RXT2-like, N-terminal STE PF02200.11 GAO82248.1 - 3.3e-62 207.4 0.1 6e-62 206.6 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 GAO82248.1 - 5.6e-12 45.2 9.4 1.1e-06 28.5 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO82248.1 - 7e-10 38.7 11.4 1.1e-09 38.1 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO82248.1 - 1.1e-09 37.8 10.2 9e-05 22.5 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAO82248.1 - 0.0057 16.5 0.4 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO82248.1 - 0.018 15.1 0.3 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 GAO82248.1 - 0.035 14.4 2.3 0.059 13.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-RING_3 PF14369.1 GAO82248.1 - 0.051 13.5 0.2 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-finger FYDLN_acid PF09538.5 GAO82248.1 - 0.14 12.7 0.3 0.39 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 GAO82248.1 - 0.95 9.6 3.6 2.5 8.3 2.5 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 GAO82248.1 - 1.2 8.8 4.9 1.9 8.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_2 PF13347.1 GAO82249.1 - 8.5e-07 27.7 9.3 8.5e-07 27.7 6.4 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1772 PF08592.6 GAO82249.1 - 0.23 11.2 6.1 1.8 8.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Na_H_Exchanger PF00999.16 GAO82250.1 - 1.3e-66 224.7 40.8 1.6e-66 224.4 28.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease_2 PF13520.1 GAO82251.1 - 5.7e-62 209.6 43.0 7.2e-62 209.2 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO82251.1 - 4.3e-14 51.7 33.1 6.3e-14 51.1 23.0 1.2 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.1 GAO82251.1 - 0.043 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase BCLP PF12304.3 GAO82251.1 - 0.18 11.1 6.5 3.6 6.9 1.1 3.9 4 0 0 4 4 4 0 Beta-casein like protein ADH_N PF08240.7 GAO82252.1 - 3.6e-31 107.1 0.6 6.5e-31 106.3 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO82252.1 - 6.4e-28 96.9 0.5 6.4e-28 96.9 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAO82252.1 - 0.0086 15.6 0.3 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 GAO82252.1 - 0.019 14.1 0.2 0.031 13.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAO82252.1 - 0.085 13.7 0.1 0.16 12.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1967 PF09269.6 GAO82252.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) SNF2_N PF00176.18 GAO82253.1 - 2.3e-70 236.7 3.6 2.3e-70 236.7 2.5 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 GAO82253.1 - 7.5e-53 178.3 20.1 7.5e-53 178.3 13.9 4.2 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 GAO82253.1 - 1.2e-16 60.3 0.0 3.5e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aminotran_1_2 PF00155.16 GAO82254.1 - 2.5e-88 296.5 0.0 3.1e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAO82254.1 - 3.2e-06 25.6 0.0 5.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO82254.1 - 6.5e-06 25.1 0.0 1.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAO82254.1 - 8e-05 21.8 0.5 0.00025 20.1 0.4 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAO82254.1 - 0.012 14.7 0.5 0.025 13.7 0.4 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Adeno_hexon_C PF03678.9 GAO82254.1 - 0.14 11.5 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain RNA_pol_I_A49 PF06870.7 GAO82255.1 - 4.8e-54 183.4 0.5 3.5e-39 134.4 0.3 2.9 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor DUF1153 PF06627.6 GAO82255.1 - 0.17 11.7 1.2 3.1 7.7 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1153) MFS_1 PF07690.11 GAO82256.1 - 4.5e-38 130.8 27.8 4.5e-38 130.8 19.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF63 PF01889.12 GAO82256.1 - 0.06 13.4 4.1 0.03 14.4 0.6 2.1 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 Peroxin-3 PF04882.7 GAO82257.1 - 5.2e-145 483.4 0.0 6.1e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 BaffR-Tall_bind PF09256.5 GAO82257.1 - 0.033 13.7 0.1 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding DUF1649 PF07855.7 GAO82258.1 - 4.4e-66 221.5 0.0 5e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) TB2_DP1_HVA22 PF03134.14 GAO82259.1 - 3.2e-31 106.9 6.2 4.3e-31 106.5 4.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SNF2_N PF00176.18 GAO82260.1 - 1.2e-83 280.4 1.0 1.2e-83 280.4 0.7 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 GAO82260.1 - 4.4e-26 90.6 0.3 1.5e-25 88.9 0.2 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 GAO82260.1 - 2.2e-19 69.3 1.7 2.2e-19 69.3 1.2 4.2 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 GAO82260.1 - 3.1e-17 62.1 2.8 2.1e-16 59.5 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 GAO82260.1 - 8.9e-17 60.6 16.6 8.9e-17 60.6 11.5 3.2 3 0 0 3 3 3 1 HSA QLQ PF08880.6 GAO82260.1 - 9.2e-12 44.1 0.8 9.2e-12 44.1 0.5 2.9 3 0 0 3 3 3 1 QLQ M11L PF11099.3 GAO82260.1 - 0.058 13.1 0.1 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11L like BAR PF03114.13 GAO82261.1 - 5.6e-49 166.7 8.4 8e-49 166.2 5.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 GAO82261.1 - 9.9e-06 24.6 5.5 1.7e-05 23.8 3.8 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 GAO82261.1 - 0.75 8.7 12.3 0.1 11.5 5.9 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Ada_Zn_binding PF02805.11 GAO82262.1 - 5.2e-30 102.8 6.4 8.7e-30 102.1 4.4 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 GAO82262.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 GAO82262.1 - 0.00076 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.13 GAO82263.1 - 1.6e-37 128.1 4.3 1.6e-37 128.1 3.0 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAO82263.1 - 4.1e-15 55.5 0.0 9.1e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 GAO82264.1 - 0.001 18.8 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.5 GAO82265.1 - 2.1e-32 111.6 1.5 3e-32 111.1 1.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 GAO82266.1 - 2.5e-66 223.8 0.0 2.8e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase EST1_DNA_bind PF10373.4 GAO82267.1 - 6.4e-66 222.3 1.0 7.4e-66 222.2 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 GAO82267.1 - 2e-24 86.0 0.1 4.5e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 GAO82267.1 - 0.00015 21.2 1.0 0.00038 20.0 0.7 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 GAO82267.1 - 0.021 15.4 1.2 0.074 13.7 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 GAO82269.1 - 1.2e-67 227.8 0.0 2.4e-67 226.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82269.1 - 8.5e-49 165.9 0.0 2.5e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 GAO82269.1 - 8.9e-33 112.3 0.0 2.1e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 GAO82269.1 - 2.3e-15 56.4 0.1 4.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAO82269.1 - 2.3e-13 49.7 0.1 7.2e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 GAO82269.1 - 1.4e-07 30.7 0.0 0.00042 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 GAO82269.1 - 8.8e-06 26.1 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 GAO82269.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 GAO82270.1 - 1.9e-26 91.6 0.0 3e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus UCH_1 PF13423.1 GAO82271.1 - 4.8e-76 256.0 0.0 2.3e-75 253.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pep3_Vps18 PF05131.9 GAO82272.1 - 3.2e-49 166.1 0.1 2.3e-48 163.3 0.0 2.4 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 GAO82272.1 - 5.1e-10 39.1 4.4 3e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 GAO82272.1 - 0.0025 17.5 0.4 0.0058 16.3 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAO82272.1 - 0.0032 17.2 0.4 0.0074 16.0 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.4 GAO82272.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF1664 PF07889.7 GAO82272.1 - 0.024 14.4 1.0 0.6 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NTS PF15447.1 GAO82272.1 - 0.12 12.8 0.2 0.28 11.5 0.2 1.7 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 zf-rbx1 PF12678.2 GAO82272.1 - 0.15 12.2 0.3 0.47 10.6 0.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger DUF2175 PF09943.4 GAO82272.1 - 0.54 10.3 2.9 3.3 7.8 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Zn_clus PF00172.13 GAO82273.1 - 1.4e-10 40.8 10.4 2.6e-10 40.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO82273.1 - 3.6e-05 22.7 0.3 0.00016 20.6 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 GAO82274.1 - 2.7e-59 200.4 0.0 4e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82274.1 - 8.4e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO82274.1 - 2.4e-11 43.1 0.0 7.2e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAO82274.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 GAO82275.1 - 2.5e-34 117.9 0.1 5e-34 117.0 0.0 1.6 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Spo12 PF05032.7 GAO82276.1 - 1.2e-16 59.9 2.8 1.2e-16 59.9 1.9 2.1 2 1 1 3 3 3 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 GAO82277.1 - 2.7e-30 105.4 1.0 4.4e-30 104.7 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO82277.1 - 5.1e-16 57.9 0.0 1.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO82277.1 - 1.4e-15 57.6 1.8 2.9e-15 56.7 1.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO82277.1 - 1.1e-14 55.0 0.1 2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MMR_HSR1 PF01926.18 GAO82278.1 - 1e-17 64.1 0.2 1.5e-14 53.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO82278.1 - 2.5e-07 30.1 0.3 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 GAO82278.1 - 0.00038 20.3 1.0 0.17 11.7 0.1 3.2 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 GAO82278.1 - 0.00043 19.5 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAO82278.1 - 0.0035 16.4 0.0 0.0087 15.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 GAO82278.1 - 0.035 13.5 0.3 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 GAO82278.1 - 0.062 13.8 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein LTV PF04180.9 GAO82279.1 - 6.8e-79 266.3 2.7 1.1e-78 265.6 1.9 1.3 1 1 0 1 1 1 1 Low temperature viability protein YL1 PF05764.8 GAO82279.1 - 3 7.4 9.1 22 4.5 6.3 2.3 1 1 0 1 1 1 0 YL1 nuclear protein PLDc_2 PF13091.1 GAO82280.1 - 7.4e-15 54.8 0.0 5.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAO82280.1 - 1e-07 31.5 0.3 0.11 12.2 0.0 3.4 3 0 0 3 3 3 3 Phospholipase D Active site motif Glyco_trans_1_2 PF13524.1 GAO82280.1 - 0.064 13.5 0.0 6.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 NDUFA12 PF05071.11 GAO82281.1 - 6.5e-27 94.0 0.2 8.8e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribonuclease PF00545.15 GAO82281.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 ribonuclease TPR_2 PF07719.12 GAO82282.1 - 4.8e-07 29.1 16.6 0.35 10.8 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAO82282.1 - 9.3e-07 28.4 7.8 0.12 12.0 0.2 5.3 5 1 0 5 5 5 2 TPR repeat TPR_14 PF13428.1 GAO82282.1 - 6.9e-06 26.2 25.7 4.2 8.2 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO82282.1 - 8e-06 25.2 6.6 0.29 10.8 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82282.1 - 1.8e-05 24.1 2.3 0.35 10.7 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO82282.1 - 0.00011 22.0 17.7 0.0095 15.8 0.7 5.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAO82282.1 - 0.00066 19.5 4.4 0.34 10.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAO82282.1 - 0.00077 19.4 1.5 12 6.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO82282.1 - 0.012 15.3 15.9 11 6.0 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO82282.1 - 0.051 14.2 27.0 3.9 8.2 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat RIX1 PF08167.7 GAO82283.1 - 6e-61 204.9 0.7 6e-61 204.9 0.5 1.9 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Cwf_Cwc_15 PF04889.7 GAO82283.1 - 3.5 7.2 6.3 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MBOAT_2 PF13813.1 GAO82284.1 - 3.9e-21 74.9 3.0 3.9e-21 74.9 2.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 GAO82285.1 - 1.3e-34 119.4 50.5 4.9e-34 117.5 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SNF2_N PF00176.18 GAO82286.1 - 5.1e-69 232.3 0.0 7.5e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAO82286.1 - 4e-19 68.5 0.0 7.6e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 GAO82286.1 - 5.6e-11 42.0 6.2 1.5e-10 40.7 4.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAO82286.1 - 6.2e-09 35.7 6.3 6.2e-09 35.7 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO82286.1 - 8.4e-09 34.9 6.0 2.1e-08 33.6 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 GAO82286.1 - 1.4e-08 34.4 0.0 3.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 GAO82286.1 - 1.8e-08 33.9 4.0 1.8e-08 33.9 2.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAO82286.1 - 2.5e-08 33.6 6.4 4.6e-08 32.8 4.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 GAO82286.1 - 2.4e-07 30.1 3.8 7.5e-07 28.5 2.3 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 GAO82286.1 - 1.2e-05 24.8 4.5 2.5e-05 23.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAO82286.1 - 1.6e-05 24.9 1.6 4.6e-05 23.4 1.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 GAO82286.1 - 1.8e-05 24.6 1.4 4.7e-05 23.2 0.0 2.4 3 0 0 3 3 2 1 U-box domain zf-RING_UBOX PF13445.1 GAO82286.1 - 3.4e-05 23.4 3.1 9.9e-05 21.9 2.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF1644 PF07800.7 GAO82286.1 - 0.063 13.1 3.1 5.2 6.8 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-Apc11 PF12861.2 GAO82286.1 - 0.066 13.0 1.2 0.16 11.7 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HDA2-3 PF11496.3 GAO82286.1 - 0.09 11.5 0.0 3.7 6.2 0.0 2.6 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Rad50_zn_hook PF04423.9 GAO82286.1 - 0.18 11.2 1.6 0.66 9.4 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 GAO82286.1 - 1.1 8.9 4.2 2.9 7.5 3.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SNF2_N PF00176.18 GAO82287.1 - 1.8e-48 164.9 1.3 4.6e-48 163.5 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO82287.1 - 1.2e-12 47.4 0.0 3.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO82287.1 - 6.4e-07 29.3 0.4 2.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.12 GAO82287.1 - 0.00033 20.4 0.1 0.00081 19.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAO82287.1 - 0.052 13.7 0.1 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_34 PF13872.1 GAO82287.1 - 0.071 11.8 0.0 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 GSH_synth_ATP PF03917.12 GAO82288.1 - 1.6e-99 333.0 0.0 1.9e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAO82288.1 - 4.2e-30 103.9 0.0 8.5e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF167 PF02594.11 GAO82292.1 - 9.1e-18 63.9 0.1 1.3e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Bestrophin PF01062.16 GAO82294.1 - 7.5e-51 172.8 0.5 2.6e-49 167.7 0.3 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1097 PF06496.6 GAO82294.1 - 0.02 14.7 3.5 0.025 14.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) DUF876 PF05936.7 GAO82294.1 - 0.12 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) DUF4231 PF14015.1 GAO82295.1 - 1.8 8.6 7.3 0.56 10.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Aminotran_3 PF00202.16 GAO82296.1 - 1e-106 356.6 0.0 1.2e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAO82296.1 - 0.046 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.8 GAO82297.1 - 1.6e-31 108.0 0.2 1.9e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Metallophos PF00149.23 GAO82298.1 - 5.5e-40 136.8 0.0 9e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 GAO82298.1 - 1.2e-30 105.3 0.4 2.8e-30 104.1 0.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 GAO82298.1 - 1.1e-20 72.9 2.1 3.1e-15 55.5 0.2 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAO82298.1 - 6.4e-11 41.3 3.8 5.1e-05 22.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO82298.1 - 1.3e-09 37.1 4.7 0.0044 16.8 0.1 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAO82298.1 - 4.5e-07 30.3 2.8 0.0049 17.5 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAO82298.1 - 0.00036 20.3 0.1 0.0028 17.4 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO82298.1 - 0.00088 19.5 0.5 0.11 12.8 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAO82298.1 - 0.0031 17.3 0.5 0.019 14.8 0.1 2.3 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 GAO82298.1 - 0.0082 16.6 1.6 0.42 11.3 0.1 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO82298.1 - 0.014 15.8 3.8 0.3 11.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 GAO82298.1 - 0.014 15.2 3.6 0.049 13.5 0.7 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Metallophos_2 PF12850.2 GAO82298.1 - 0.02 14.7 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Apc3 PF12895.2 GAO82298.1 - 0.097 12.8 0.9 2.4 8.3 0.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAO82298.1 - 0.54 10.5 3.6 9.4 6.7 0.1 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF89 PF01937.14 GAO82299.1 - 1.3e-139 464.9 0.0 1.5e-139 464.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 ketoacyl-synt PF00109.21 GAO82300.1 - 3.6e-73 246.1 0.0 7.7e-73 245.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO82300.1 - 1.7e-47 162.3 0.1 3.4e-46 158.0 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO82300.1 - 1.2e-35 121.9 0.6 2.3e-35 121.0 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO82300.1 - 1.2e-08 35.1 0.6 2.8e-08 33.9 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO82300.1 - 0.0038 16.2 0.1 0.0077 15.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.13 GAO82301.1 - 7.2e-28 97.4 0.0 1.5e-27 96.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAO82301.1 - 0.061 13.1 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Cut12 PF11500.3 GAO82302.1 - 7.6e-53 178.2 11.4 7.6e-53 178.2 7.9 4.0 2 1 0 3 3 3 1 Spindle pole body formation-associated protein HGTP_anticodon2 PF12745.2 GAO82303.1 - 2.6e-83 279.3 1.1 2.6e-83 279.3 0.8 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 GAO82303.1 - 7.3e-74 248.1 0.0 3.6e-38 131.1 0.0 4.9 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82303.1 - 1.7e-42 145.2 0.0 1.8e-18 66.5 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 GAO82303.1 - 2.4e-17 62.8 0.2 7.1e-17 61.3 0.1 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 GAO82303.1 - 3.2e-12 46.1 1.1 1.1e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 GAO82303.1 - 1.4e-05 24.2 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAO82303.1 - 0.00014 21.7 4.3 0.0011 18.7 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.15 GAO82303.1 - 0.029 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain RRM_1 PF00076.17 GAO82304.1 - 8.6e-09 34.9 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82304.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82304.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO82304.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 GAO82304.1 - 0.14 11.8 1.7 0.23 11.1 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TGS PF02824.16 GAO82305.1 - 1.5e-21 75.9 0.1 3.4e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAO82305.1 - 3.9e-19 68.7 0.1 1.3e-18 67.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO82305.1 - 5.8e-12 45.1 0.0 9.7e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAO82305.1 - 2.7e-05 24.0 0.2 0.024 14.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 GAO82305.1 - 0.0022 18.4 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 GAO82305.1 - 0.028 13.2 0.1 0.062 12.0 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 GAO82305.1 - 0.042 12.6 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AIG1 PF04548.11 GAO82305.1 - 0.053 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CPSase_sm_chain PF00988.17 GAO82306.1 - 5.8e-46 155.2 0.0 1.1e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 GAO82306.1 - 8.1e-46 155.8 0.0 1.2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAO82306.1 - 4.8e-06 26.1 0.1 0.00015 21.2 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 Fungal_trans PF04082.13 GAO82307.1 - 1.7e-10 40.2 0.0 2.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIG-X PF08320.7 GAO82308.1 - 3.7e-73 245.2 0.0 5.3e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 HSP20 PF00011.16 GAO82309.1 - 4.6e-07 29.6 1.3 4.3e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Hsp20/alpha crystallin family Ank_2 PF12796.2 GAO82311.1 - 3.3e-62 206.8 15.1 2.4e-13 50.1 0.0 7.6 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82311.1 - 4.4e-48 158.7 24.7 5.6e-08 32.2 0.1 12.6 12 2 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 GAO82311.1 - 2.7e-45 151.3 20.0 6.7e-13 48.4 0.2 8.9 7 1 2 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO82311.1 - 7.2e-45 150.6 17.3 8.1e-08 32.5 0.0 11.9 5 4 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82311.1 - 4.6e-40 131.6 15.7 7.7e-06 25.6 0.1 12.6 11 1 0 11 11 11 8 Ankyrin repeat NACHT PF05729.7 GAO82311.1 - 5.9e-08 32.5 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAO82311.1 - 0.014 15.5 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 GAO82312.1 - 7.3e-21 74.7 0.0 1e-19 71.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO82312.1 - 4.8e-09 36.1 0.0 8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO82312.1 - 0.00033 20.1 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO82312.1 - 0.003 16.3 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO82312.1 - 0.0033 16.3 0.0 0.0052 15.7 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAO82312.1 - 0.036 14.0 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO82312.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAO82313.1 - 7e-13 48.3 0.0 1.3e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAO82313.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 GAO82314.1 - 0.00054 19.8 11.8 0.00095 19.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 GAO82315.1 - 3.8e-33 113.6 1.7 1.4e-08 34.9 0.2 5.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO82315.1 - 4.4e-24 84.4 11.0 0.00024 21.5 0.1 8.4 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO82315.1 - 2.7e-21 75.0 13.6 1.2e-05 25.3 0.1 9.1 6 3 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82315.1 - 5e-20 69.6 12.7 0.00014 21.7 0.0 10.5 11 0 0 11 11 11 3 Ankyrin repeat Ank PF00023.25 GAO82315.1 - 6.7e-18 63.5 21.9 0.00012 21.6 0.0 10.2 10 2 0 10 10 10 4 Ankyrin repeat HsbA PF12296.3 GAO82316.1 - 1.8e-21 76.2 1.0 2.8e-21 75.6 0.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 GAO82316.1 - 0.87 9.4 5.2 2.9 7.7 0.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Strumpellin PF10266.4 GAO82317.1 - 0.11 9.9 1.8 0.14 9.5 1.2 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin AAA_32 PF13654.1 GAO82317.1 - 0.23 10.0 3.8 0.46 9.0 0.9 2.0 1 1 1 2 2 2 0 AAA domain GMC_oxred_N PF00732.14 GAO82318.1 - 2.3e-54 184.5 0.0 3.4e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO82318.1 - 2.4e-32 112.2 0.0 4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAO82318.1 - 3.8e-07 29.3 0.0 0.00083 18.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO82318.1 - 2.1e-05 24.4 0.0 6.2e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAO82318.1 - 3.2e-05 22.9 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO82318.1 - 0.00011 21.3 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAO82318.1 - 0.00021 19.9 0.0 0.011 14.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAO82318.1 - 0.0029 17.4 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO82318.1 - 0.0045 15.8 0.0 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAO82318.1 - 0.022 13.8 0.0 0.054 12.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 GAO82318.1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO82318.1 - 0.094 12.7 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.13 GAO82319.1 - 2e-18 66.1 27.4 2e-18 66.1 19.0 2.1 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein AAA PF00004.24 GAO82320.1 - 2.5e-18 66.5 0.0 7.4e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO82320.1 - 0.004 17.1 0.9 0.014 15.3 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAO82320.1 - 0.0044 16.9 0.0 0.023 14.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO82320.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAO82320.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 GAO82320.1 - 0.03 15.1 2.1 0.099 13.4 0.2 2.9 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO82320.1 - 0.038 14.1 0.6 0.35 11.0 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.9 GAO82320.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAO82320.1 - 0.049 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAO82320.1 - 0.055 13.2 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 GAO82320.1 - 0.071 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain 5_nucleotid_C PF02872.13 GAO82320.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain GFA PF04828.9 GAO82322.1 - 2.2e-19 69.1 0.3 3e-19 68.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme COesterase PF00135.23 GAO82323.1 - 1.2e-55 189.2 0.0 1.5e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO82323.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.2 GAO82324.1 - 2.4e-104 341.9 0.0 2.6e-23 82.1 0.0 5.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82324.1 - 4.4e-96 310.2 0.0 7.5e-10 38.1 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 GAO82324.1 - 2.6e-68 225.2 0.1 3.2e-10 40.2 0.0 8.4 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82324.1 - 6.3e-64 205.5 0.0 1.6e-06 27.7 0.0 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.1 GAO82324.1 - 6.7e-62 204.1 10.2 3.5e-09 36.6 0.0 8.6 2 2 9 11 11 11 11 Ankyrin repeats (many copies) DUF1110 PF06533.7 GAO82324.1 - 0.0033 17.2 0.1 3.7 7.3 0.0 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF1110) GPI-anchored PF10342.4 GAO82324.1 - 0.0033 17.8 0.4 15 6.1 0.0 4.9 3 2 1 5 5 5 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_zinc_N_2 PF13602.1 GAO82325.1 - 5.2e-16 59.7 0.0 1.1e-15 58.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO82325.1 - 8.5e-15 54.4 0.3 1.6e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO82325.1 - 2e-09 37.1 0.1 4.2e-08 32.9 0.0 2.8 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.3 GAO82325.1 - 0.002 16.7 0.2 0.0029 16.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ELFV_dehydrog PF00208.16 GAO82325.1 - 0.018 14.5 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase bZIP_1 PF00170.16 GAO82327.1 - 0.1 12.5 5.0 0.19 11.7 3.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_gE PF02480.11 GAO82328.1 - 0.00013 20.4 0.0 0.00018 19.9 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 GAO82328.1 - 0.0027 16.9 1.0 0.0058 15.9 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CSF-1 PF05337.6 GAO82328.1 - 0.039 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DUF4328 PF14219.1 GAO82328.1 - 0.16 11.2 1.6 3.1 7.0 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4328) Sugar_tr PF00083.19 GAO82329.1 - 2.6e-83 280.1 24.4 3e-83 279.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO82329.1 - 1.9e-22 79.4 41.9 3e-15 55.8 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAO82330.1 - 1.1e-08 34.8 14.6 2.4e-08 33.7 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 GAO82331.1 - 7.4e-34 115.7 0.1 1.9e-33 114.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO82331.1 - 2.8e-20 72.1 0.4 4.5e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO82331.1 - 0.00064 20.6 0.1 0.0016 19.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAO82331.1 - 0.0069 16.9 0.1 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 GAO82331.1 - 0.037 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 GAO82331.1 - 0.071 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO82331.1 - 0.086 13.2 0.3 0.33 11.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 GAO82331.1 - 0.11 12.3 0.2 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FGGY_C PF02782.11 GAO82332.1 - 1.1e-46 158.9 0.8 2e-46 158.1 0.3 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAO82332.1 - 9.9e-21 74.1 0.0 9.9e-19 67.6 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain LexA_DNA_bind PF01726.11 GAO82332.1 - 0.16 11.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 LexA DNA binding domain Epimerase PF01370.16 GAO82333.1 - 1.4e-22 80.2 0.0 2.2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO82333.1 - 2.5e-11 42.8 0.0 3.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO82333.1 - 7.8e-10 38.0 0.1 6.8e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAO82333.1 - 1.2e-07 31.7 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO82333.1 - 2.3e-06 27.7 0.0 4.1e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO82333.1 - 9.6e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO82333.1 - 0.0046 15.8 0.0 0.021 13.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO82333.1 - 0.036 12.9 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 GAO82333.1 - 0.039 13.1 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family S1-P1_nuclease PF02265.11 GAO82334.1 - 5.7e-75 252.1 1.6 6.5e-75 252.0 1.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Ctr PF04145.10 GAO82335.1 - 2.7 8.0 5.4 0.73 9.8 1.3 1.7 2 0 0 2 2 2 0 Ctr copper transporter family Peptidase_M49 PF03571.10 GAO82337.1 - 4.7e-197 655.4 0.0 6e-197 655.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 TPR_11 PF13414.1 GAO82338.1 - 2e-09 36.9 4.1 3.3e-06 26.6 0.8 2.7 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAO82338.1 - 5.8e-07 28.9 6.0 0.0023 17.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO82338.1 - 0.00026 20.5 0.8 0.43 10.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAO82338.1 - 0.00029 21.0 1.4 0.012 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO82338.1 - 0.00034 20.5 4.1 0.025 14.4 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO82338.1 - 0.00041 20.6 0.1 0.016 15.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO82338.1 - 0.00092 19.8 2.4 1 10.1 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82338.1 - 0.0016 18.0 0.4 0.064 13.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAO82338.1 - 0.0036 17.1 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO82338.1 - 0.008 15.7 1.1 3.5 7.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.5 GAO82338.1 - 0.009 15.1 0.1 0.36 9.8 0.0 2.1 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like Apc3 PF12895.2 GAO82338.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAO82338.1 - 0.054 14.1 3.2 0.16 12.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO82338.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.0 4 1 1 5 5 5 0 Tetratricopeptide repeat MARVEL PF01284.18 GAO82339.1 - 4.5e-09 36.2 5.8 6.4e-09 35.7 4.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 GAO82339.1 - 0.0075 15.0 3.4 0.011 14.5 2.4 1.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter Peptidase_M56 PF05569.6 GAO82339.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF161 PF02588.10 GAO82339.1 - 0.095 13.0 1.2 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 DUF3262 PF11660.3 GAO82339.1 - 3 7.9 8.5 0.36 10.9 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) ATPgrasp_Ter PF15632.1 GAO82340.1 - 0.1 11.3 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Methyltransf_3 PF01596.12 GAO82341.1 - 1.3e-13 50.4 0.0 1.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAO82341.1 - 2.1e-08 34.9 0.0 3.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 GAO82341.1 - 0.00089 18.6 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 GAO82341.1 - 0.0099 15.9 0.0 0.029 14.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 GAO82342.1 - 4.5e-26 91.7 0.1 8.2e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO82342.1 - 1.1e-12 47.6 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 GAO82342.1 - 6.3e-05 23.3 0.1 0.00012 22.4 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO82342.1 - 6.9e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAO82342.1 - 0.0054 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAO82342.1 - 0.029 13.3 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase CoA_binding PF02629.14 GAO82342.1 - 0.088 13.3 0.1 0.21 12.0 0.1 1.6 1 1 0 1 1 1 0 CoA binding domain HPP PF04982.8 GAO82343.1 - 2.3e-34 117.7 11.5 2.3e-34 117.7 8.0 1.5 2 0 0 2 2 2 1 HPP family ResB PF05140.9 GAO82343.1 - 0.046 12.2 0.0 0.063 11.8 0.0 1.2 1 0 0 1 1 1 0 ResB-like family ABC_tran PF00005.22 GAO82344.1 - 2.1e-47 160.8 0.0 1.9e-22 80.0 0.0 2.9 2 1 1 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 GAO82344.1 - 5.5e-20 70.9 2.5 5.5e-20 70.9 1.7 3.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 GAO82344.1 - 1.9e-18 67.4 0.8 0.00079 19.4 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 GAO82344.1 - 1.4e-10 40.8 0.6 0.014 14.5 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAO82344.1 - 6.8e-09 35.1 0.4 0.00047 19.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAO82344.1 - 4.8e-08 33.5 3.7 0.083 13.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 GAO82344.1 - 4.4e-07 29.2 0.0 0.00063 18.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO82344.1 - 1.8e-06 28.1 0.0 0.061 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAO82344.1 - 2.9e-06 27.7 0.0 0.012 16.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 GAO82344.1 - 5.2e-06 26.7 0.1 0.016 15.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 GAO82344.1 - 6.2e-06 27.0 0.0 0.12 13.2 0.0 2.9 2 1 0 3 3 2 2 AAA domain NACHT PF05729.7 GAO82344.1 - 7.7e-06 25.6 0.1 0.063 12.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 GAO82344.1 - 1.1e-05 25.4 0.1 0.079 12.9 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAO82344.1 - 1.4e-05 25.1 0.5 0.057 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 GAO82344.1 - 1.8e-05 24.7 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAO82344.1 - 4.2e-05 23.4 1.3 0.044 13.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 GAO82344.1 - 4.7e-05 23.6 0.0 0.71 10.0 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAO82344.1 - 0.00011 22.3 0.6 0.93 9.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.9 GAO82344.1 - 0.00016 21.4 0.0 0.85 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAO82344.1 - 0.00031 20.2 0.6 1 8.7 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain Arch_ATPase PF01637.13 GAO82344.1 - 0.00033 20.4 0.0 0.41 10.3 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 GAO82344.1 - 0.0008 18.3 0.0 0.58 8.9 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 GAO82344.1 - 0.001 18.4 0.0 1.1 8.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAO82344.1 - 0.0012 18.7 0.0 2.2 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAO82344.1 - 0.002 17.2 0.9 0.27 10.2 0.0 3.1 5 0 0 5 5 3 1 AAA ATPase domain SbcCD_C PF13558.1 GAO82344.1 - 0.0025 17.6 0.4 0.29 11.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 GAO82344.1 - 0.0031 17.2 0.1 0.36 10.5 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 GAO82344.1 - 0.0049 15.4 0.4 6.8 5.0 0.1 3.4 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 GAO82344.1 - 0.018 14.0 1.0 3.2 6.6 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 GAO82344.1 - 0.023 14.1 0.1 0.27 10.6 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 GAO82344.1 - 0.045 13.0 0.1 3.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF2813 PF11398.3 GAO82344.1 - 0.049 12.7 1.8 4.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Ras PF00071.17 GAO82344.1 - 0.052 12.9 0.0 4.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.10 GAO82344.1 - 0.067 12.8 0.1 7.3 6.2 0.0 2.6 2 0 0 2 2 2 0 NTPase VirE PF05272.6 GAO82344.1 - 0.071 12.5 0.4 4.4 6.7 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E Dynamin_N PF00350.18 GAO82344.1 - 0.075 12.8 1.9 9.4 6.0 0.0 3.5 3 1 1 4 4 4 0 Dynamin family DUF87 PF01935.12 GAO82344.1 - 0.1 12.3 1.4 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 GAO82344.1 - 0.14 11.6 0.7 9.9 5.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Exonuc_VII_S PF02609.11 GAO82344.1 - 0.2 11.4 4.0 5.9 6.7 0.0 3.5 5 0 0 5 5 2 0 Exonuclease VII small subunit AAA_24 PF13479.1 GAO82344.1 - 0.77 9.2 4.7 9.5 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain UQ_con PF00179.21 GAO82345.1 - 1.5e-42 144.3 0.0 2.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cyclin_N PF00134.18 GAO82345.1 - 4.3e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain UBA_3 PF09288.5 GAO82345.1 - 1.4e-06 27.7 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 GAO82345.1 - 0.0005 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Ribosomal_60s PF00428.14 GAO82345.1 - 9.1 6.7 17.5 0.063 13.6 1.5 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA PF00004.24 GAO82346.1 - 1.5e-40 138.4 0.0 2.8e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 GAO82346.1 - 7.4e-30 103.1 0.0 4e-12 46.3 0.0 4.5 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82346.1 - 6.8e-18 63.4 5.8 0.011 15.4 0.0 8.0 9 0 0 9 9 8 4 Ankyrin repeat Ank_3 PF13606.1 GAO82346.1 - 3.6e-17 60.7 1.0 0.002 18.1 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 GAO82346.1 - 1.1e-16 60.8 1.4 0.0022 18.4 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO82346.1 - 1.1e-16 60.4 0.4 0.0052 16.9 0.0 7.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) AAA_22 PF13401.1 GAO82346.1 - 6.7e-07 29.5 0.1 0.00014 21.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAO82346.1 - 2.7e-05 23.2 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 GAO82346.1 - 3e-05 24.0 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAO82346.1 - 3.6e-05 23.4 0.0 0.00014 21.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO82346.1 - 0.0007 19.6 0.1 0.0034 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 GAO82346.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAO82346.1 - 0.0028 17.6 0.2 0.0095 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAO82346.1 - 0.0044 17.8 0.0 0.029 15.1 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAO82346.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO82346.1 - 0.0082 16.0 0.1 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain F-box-like PF12937.2 GAO82346.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like AAA_19 PF13245.1 GAO82346.1 - 0.014 15.1 0.3 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAO82346.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAO82346.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 GAO82346.1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAO82346.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAO82346.1 - 0.045 12.4 0.0 0.089 11.4 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 GAO82346.1 - 0.047 13.3 0.4 0.72 9.4 0.0 2.6 2 1 0 3 3 2 0 NACHT domain PhoH PF02562.11 GAO82346.1 - 0.056 12.6 0.9 0.45 9.6 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 GAO82346.1 - 0.068 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 GAO82346.1 - 0.084 12.2 2.4 0.62 9.4 0.3 2.7 2 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 GAO82346.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 GAO82346.1 - 0.11 12.1 0.2 0.3 10.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAO82346.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAO82346.1 - 0.15 11.1 0.2 1 8.3 0.1 2.1 1 1 1 2 2 2 0 KaiC Fungal_trans_2 PF11951.3 GAO82347.1 - 1.9e-08 33.3 0.0 2.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF719 PF05334.8 GAO82348.1 - 0.0086 16.1 0.8 0.01 15.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF719) Radial_spoke PF04712.7 GAO82348.1 - 0.024 13.3 5.7 0.029 13.1 3.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Sigma70_ner PF04546.8 GAO82348.1 - 0.029 13.9 5.1 0.035 13.7 3.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 GAO82348.1 - 0.033 13.6 6.1 0.042 13.3 4.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2514 PF10721.4 GAO82348.1 - 0.041 13.5 6.4 0.054 13.2 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TRAP_alpha PF03896.11 GAO82348.1 - 0.089 11.7 1.5 0.093 11.7 1.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SspB PF04386.8 GAO82348.1 - 0.13 11.9 2.5 0.18 11.3 1.7 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RNA_pol_Rpc4 PF05132.9 GAO82348.1 - 0.2 11.6 0.8 0.26 11.2 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.7 GAO82348.1 - 0.22 11.4 4.8 0.27 11.0 3.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-B_dimeris PF09026.5 GAO82348.1 - 0.34 11.1 6.6 0.41 10.9 4.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Paf1 PF03985.8 GAO82348.1 - 0.66 8.6 6.1 0.74 8.4 4.2 1.0 1 0 0 1 1 1 0 Paf1 HSP90 PF00183.13 GAO82348.1 - 0.82 7.9 4.8 0.92 7.8 3.3 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF2890 PF11081.3 GAO82348.1 - 1.4 8.9 8.5 1.6 8.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) VID27 PF08553.5 GAO82348.1 - 2 6.5 6.2 2.2 6.3 4.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein YqfQ PF14181.1 GAO82348.1 - 2.1 8.3 4.1 2.5 8.0 2.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein Cytomega_UL84 PF06284.6 GAO82348.1 - 2.3 6.5 4.5 2.7 6.3 3.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3306 PF11748.3 GAO82348.1 - 2.5 8.8 6.8 3.2 8.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Adeno_terminal PF02459.10 GAO82348.1 - 2.8 5.9 10.4 3.4 5.7 7.2 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein AIF-MLS PF14962.1 GAO82348.1 - 3.1 7.4 12.8 4 7.0 8.9 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Nop14 PF04147.7 GAO82348.1 - 3.6 5.3 8.7 4.2 5.1 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 GAO82348.1 - 4.7 7.0 8.4 6 6.7 5.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 GAO82348.1 - 5.4 5.3 11.7 6.3 5.1 8.1 1.0 1 0 0 1 1 1 0 Daxx Family Atrophin-1 PF03154.10 GAO82348.1 - 9.2 4.2 7.9 9.9 4.1 5.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 GAO82349.1 - 5.7e-19 67.2 16.3 4.2e-07 29.6 0.3 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat NOA36 PF06524.7 GAO82349.1 - 2.7 7.1 9.9 4.4 6.4 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 GAO82349.1 - 7 4.5 10.5 5.3 4.9 6.3 1.4 2 0 0 2 2 2 0 CDC45-like protein Mg_trans_NIPA PF05653.9 GAO82350.1 - 1.3e-50 172.1 8.5 2.8e-32 111.9 1.1 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA EmrE PF13536.1 GAO82350.1 - 4.4e-05 23.6 0.0 4.4e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAO82350.1 - 0.0034 17.4 2.1 0.0034 17.4 1.5 3.4 3 1 0 3 3 3 1 EamA-like transporter family DUF605 PF04652.11 GAO82350.1 - 6.9 5.9 17.3 16 4.7 12.0 1.7 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_3 PF00933.16 GAO82351.1 - 1.6e-67 227.5 0.0 2.2e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO82351.1 - 3.6e-63 213.1 0.1 5.5e-63 212.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO82351.1 - 1.3e-20 73.0 0.5 1.3e-20 73.0 0.4 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 GAO82351.1 - 0.016 14.0 0.1 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain Sugarporin_N PF11471.3 GAO82352.1 - 0.048 13.3 2.3 0.18 11.4 1.6 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Med30 PF11315.3 GAO82352.1 - 0.065 13.3 6.9 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 30 FlaC_arch PF05377.6 GAO82352.1 - 0.13 12.1 1.0 0.37 10.7 0.7 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Rootletin PF15035.1 GAO82352.1 - 0.23 11.3 12.6 0.03 14.3 1.2 2.6 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 GAO82352.1 - 0.49 10.1 6.6 3 7.6 0.9 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FadA PF09403.5 GAO82352.1 - 1 9.3 5.7 0.78 9.7 2.0 2.2 3 0 0 3 3 3 0 Adhesion protein FadA TBPIP PF07106.8 GAO82352.1 - 1.4 8.4 6.0 5.2 6.5 0.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC-167 PF15188.1 GAO82352.1 - 1.8 8.5 8.5 0.28 11.1 0.4 3.3 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF972 PF06156.8 GAO82352.1 - 2.8 8.3 10.7 1.4 9.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 GAO82352.1 - 7.9 5.6 14.1 0.11 11.6 1.7 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 GAO82352.1 - 8.4 5.9 6.3 14 5.2 2.6 2.4 2 0 0 2 2 2 0 Septum formation initiator GRAM PF02893.15 GAO82353.1 - 3.6e-17 61.6 0.0 8.4e-17 60.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain DUF2985 PF11204.3 GAO82354.1 - 2.1e-26 91.4 4.9 2.1e-26 91.4 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) RRM_1 PF00076.17 GAO82355.1 - 2.4e-32 110.3 0.3 3.3e-15 55.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82355.1 - 8.9e-24 83.2 0.0 5.8e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82355.1 - 4.7e-08 32.7 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 GAO82355.1 - 0.041 13.5 0.1 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain API5 PF05918.6 GAO82355.1 - 0.73 8.2 4.6 1 7.7 3.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.13 GAO82356.1 - 0.03 14.1 0.1 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 GAO82357.1 - 7e-55 185.3 0.0 1e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAO82357.1 - 9.9e-26 89.3 0.0 2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 GAO82357.1 - 5.5e-16 58.2 0.0 4.2e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO82357.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 GAO82357.1 - 0.014 14.9 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV MMR_HSR1 PF01926.18 GAO82357.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 GAO82358.1 - 2.5e-16 59.6 2.3 3.8e-16 59.0 1.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAO82358.1 - 4.6e-08 32.8 0.0 9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 GAO82358.1 - 0.11 11.7 0.3 0.23 10.6 0.2 1.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein GFA PF04828.9 GAO82359.1 - 5.7e-19 67.8 1.3 9.1e-19 67.2 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 GAO82359.1 - 0.15 11.6 0.2 0.15 11.6 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 GAO82359.1 - 0.28 10.9 0.2 0.28 10.9 0.2 2.6 3 0 0 3 3 3 0 Nudix N-terminal Tho2 PF11262.3 GAO82360.1 - 1.4e-95 319.8 0.0 2e-95 319.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 GAO82360.1 - 4.4e-30 103.2 0.4 3.9e-29 100.2 0.0 2.7 3 0 0 3 3 3 1 Transcription- and export-related complex subunit Epimerase PF01370.16 GAO82360.1 - 7.2e-11 41.9 0.0 2.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO82360.1 - 3.5e-07 29.7 0.1 5.8e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAO82360.1 - 7.4e-06 26.2 0.1 2.3e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAO82360.1 - 0.005 15.5 0.1 0.024 13.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO82360.1 - 0.0098 14.8 0.0 0.03 13.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 GAO82360.1 - 0.024 14.7 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAO82360.1 - 0.033 13.1 0.1 0.055 12.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_trans_1_4 PF13692.1 GAO82360.1 - 0.17 12.0 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_hydro_3 PF00933.16 GAO82361.1 - 6.5e-83 278.1 0.0 9.6e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO82361.1 - 8.2e-65 218.5 0.0 4.6e-64 216.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO82361.1 - 8.8e-24 83.2 0.9 3.4e-23 81.3 0.4 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 GAO82361.1 - 4.3e-17 62.1 0.1 8.1e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.13 GAO82361.1 - 0.00076 19.4 0.2 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 BatD PF13584.1 GAO82361.1 - 0.18 10.3 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance Abhydrolase_1 PF00561.15 GAO82362.1 - 1.1e-45 155.9 0.0 3.1e-45 154.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO82362.1 - 6.4e-15 55.6 0.5 4.9e-14 52.7 0.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO82362.1 - 0.00024 20.8 0.0 0.039 13.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family PEP_mutase PF13714.1 GAO82363.1 - 2.6e-72 242.8 1.1 2.9e-72 242.7 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.16 GAO82363.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.7 1 1 1 2 2 2 0 Radical SAM superfamily SAP PF02037.22 GAO82364.1 - 1.3e-08 34.1 0.1 2.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 GAO82364.1 - 0.0004 20.1 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO82364.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Solute_trans_a PF03619.11 GAO82365.1 - 8.1e-74 248.3 15.8 1e-73 248.0 10.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF457 PF04307.9 GAO82365.1 - 0.31 10.3 3.8 0.56 9.5 2.7 1.5 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Brr6_like_C_C PF10104.4 GAO82365.1 - 0.66 9.4 6.5 0.26 10.7 0.8 2.5 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain JAB PF01398.16 GAO82366.1 - 2e-09 37.2 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAO82366.1 - 0.015 15.3 0.0 0.22 11.6 0.0 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function RNA_pol_3_Rpc31 PF11705.3 GAO82367.1 - 8e-69 232.1 14.4 1.1e-68 231.6 10.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peripla_BP_3 PF13377.1 GAO82367.1 - 0.052 13.5 0.2 0.052 13.5 0.1 1.9 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Flavodoxin_1 PF00258.20 GAO82368.1 - 7.3e-32 110.3 0.0 1.4e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 GAO82368.1 - 5.7e-31 107.6 0.0 1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAO82368.1 - 6.5e-14 52.4 0.0 3e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAO82368.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 GAO82368.1 - 0.0044 16.4 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain ETF PF01012.16 GAO82369.1 - 3e-38 131.1 0.6 3.8e-38 130.7 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF500 PF04366.7 GAO82370.1 - 3.8e-44 149.1 0.0 6.6e-44 148.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF3403 PF11883.3 GAO82370.1 - 3.2 8.1 13.7 0.5 10.6 0.4 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3403) Peptidase_S10 PF00450.17 GAO82371.1 - 2e-86 290.7 1.7 4.6e-86 289.5 1.2 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.15 GAO82371.1 - 3.3e-60 203.0 0.0 1.1e-59 201.3 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAO82371.1 - 5.7e-45 152.2 0.5 9e-45 151.6 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 GAO82371.1 - 7.3e-21 73.9 0.5 2e-20 72.5 0.3 1.8 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.2 GAO82371.1 - 4.8e-07 29.5 0.1 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAO82371.1 - 1.7e-06 28.0 0.0 4.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DnaJ PF00226.26 GAO82372.1 - 1.3e-26 92.0 7.2 2e-26 91.4 5.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAO82372.1 - 2.6e-23 81.7 2.2 3.1e-21 75.0 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain Malate_DH PF12434.3 GAO82372.1 - 0.062 13.0 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Malate dehydrogenase enzyme SNF2_N PF00176.18 GAO82374.1 - 6.5e-13 48.1 0.1 9.1e-13 47.6 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain BASP1 PF05466.7 GAO82374.1 - 0.7 9.6 4.6 1.3 8.8 3.2 1.3 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Cu_amine_oxid PF01179.15 GAO82375.1 - 4.8e-169 562.4 0.0 6.2e-169 562.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAO82375.1 - 1.5e-21 76.3 0.7 1.7e-20 72.9 0.0 2.3 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAO82375.1 - 3.6e-15 55.8 0.0 6.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.15 GAO82376.1 - 2.3e-64 217.2 0.0 3.2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 GAO82377.1 - 9.4e-18 63.6 1.8 1.4e-17 63.1 1.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family MdcE PF06833.6 GAO82377.1 - 0.031 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) WD40 PF00400.27 GAO82378.1 - 2.3e-33 112.8 4.5 4.2e-06 26.4 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAO82378.1 - 4.1e-05 22.9 0.0 0.8 9.2 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.23 GAO82379.1 - 1.2e-73 247.8 0.0 1.6e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO82379.1 - 1.9e-15 57.5 0.3 6.2e-15 55.9 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CNH PF00780.17 GAO82380.1 - 2e-74 250.4 0.0 3.3e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 GAO82380.1 - 6.6e-32 110.8 1.2 1.1e-31 110.0 0.8 1.4 1 0 0 1 1 1 1 RhoGEF domain 2OG-FeII_Oxy_2 PF13532.1 GAO82380.1 - 1e-28 100.5 0.0 5.9e-28 98.0 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PH_5 PF15405.1 GAO82380.1 - 7.1e-14 51.9 0.0 5e-13 49.1 0.0 2.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 GAO82380.1 - 0.0075 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Phe_tRNA-synt_N PF02912.13 GAO82380.1 - 0.022 14.4 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain SHOCT PF09851.4 GAO82380.1 - 0.36 10.3 2.0 0.63 9.6 0.2 2.1 2 0 0 2 2 2 0 Short C-terminal domain Flu_NS2 PF00601.14 GAO82380.1 - 0.83 9.9 2.0 1.7 8.8 0.7 1.9 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) RabGAP-TBC PF00566.13 GAO82381.1 - 1.3e-46 158.7 0.0 2.2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 GAO82381.1 - 0.00024 20.6 0.1 0.0043 16.8 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 GAO82381.1 - 0.0051 16.1 0.8 0.022 14.0 0.6 2.2 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 GAO82381.1 - 0.013 14.7 0.3 0.045 13.0 0.2 2.1 1 0 0 1 1 1 0 EF hand GRAM PF02893.15 GAO82381.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 GRAM domain EF-hand_7 PF13499.1 GAO82381.1 - 0.016 15.3 0.3 0.074 13.1 0.2 2.2 1 1 0 1 1 1 0 EF-hand domain pair DUF4198 PF10670.4 GAO82382.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) AAA_13 PF13166.1 GAO82383.1 - 0.003 16.0 20.8 0.005 15.3 14.4 1.2 1 0 0 1 1 1 1 AAA domain DUF641 PF04859.7 GAO82383.1 - 0.0073 16.0 4.4 0.0073 16.0 3.0 2.8 1 1 2 3 3 3 1 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 GAO82383.1 - 0.017 14.9 27.9 0.04 13.7 19.3 1.6 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.6 GAO82383.1 - 0.13 10.8 21.7 0.014 14.0 11.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 GAO82383.1 - 0.33 10.3 22.1 0.94 8.8 4.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 GAO82383.1 - 0.51 9.4 5.2 0.35 10.0 0.5 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 GAO82383.1 - 0.67 9.3 12.2 0.75 9.1 2.1 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 GAO82383.1 - 1.8 7.7 27.4 3.2 6.9 4.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 GAO82383.1 - 2.8 7.4 31.6 66 3.0 3.1 3.3 1 1 1 2 2 2 0 IncA protein Phage_GP20 PF06810.6 GAO82383.1 - 3.1 7.2 23.7 0.084 12.3 4.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 GAO82383.1 - 4.6 6.9 28.1 0.77 9.5 6.3 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 GAO82383.1 - 6.5 6.5 27.9 1.7 8.4 8.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PilO PF04350.8 GAO82383.1 - 9.7 6.0 10.7 0.33 10.8 0.1 2.7 1 1 2 3 3 3 0 Pilus assembly protein, PilO adh_short_C2 PF13561.1 GAO82384.1 - 3e-19 69.7 0.0 4.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82384.1 - 5.1e-18 65.5 1.6 1.1e-17 64.4 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82384.1 - 1.1e-06 28.4 0.9 2.6e-06 27.2 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAO82384.1 - 0.044 13.2 0.3 0.13 11.6 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 GAO82386.1 - 1.1e-21 77.8 0.0 1.9e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO82386.1 - 6.4e-15 54.3 0.6 7.4e-12 44.2 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAO82386.1 - 2.7e-10 40.4 0.0 2.4e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO82386.1 - 2.4e-08 33.8 3.1 3.1e-07 30.3 0.3 3.5 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAO82386.1 - 3.2e-08 32.8 0.1 6e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAO82386.1 - 5.9e-08 32.0 0.0 0.0065 15.4 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO82386.1 - 1.4e-05 24.2 0.4 0.0011 18.0 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO82386.1 - 8.9e-05 21.5 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAO82386.1 - 0.0009 18.4 0.5 0.0025 16.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAO82386.1 - 0.0012 19.2 0.3 1.3 9.4 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO82386.1 - 0.039 13.0 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO82386.1 - 0.049 12.1 0.9 0.24 9.8 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 GAO82386.1 - 0.06 13.1 6.4 14 5.4 0.0 4.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 GAO82386.1 - 0.32 9.8 0.5 2.7 6.7 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Beta-lactamase PF00144.19 GAO82387.1 - 2.8e-35 121.9 0.0 1e-18 67.5 0.0 2.5 2 1 0 2 2 2 2 Beta-lactamase Zn_clus PF00172.13 GAO82388.1 - 6.4e-07 29.1 13.3 0.00043 20.1 0.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO82388.1 - 0.012 14.4 0.0 0.03 13.1 0.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.17 GAO82389.1 - 6.5e-76 255.7 0.0 8.3e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAO82390.1 - 4.9e-13 48.5 0.8 7.4e-13 47.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2422 PF10337.4 GAO82391.1 - 1.3e-130 436.3 0.2 3.8e-127 424.8 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAO82391.1 - 4.6e-66 222.7 0.2 7.6e-64 215.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 GAO82391.1 - 2.2e-07 30.8 14.9 2.2e-07 30.8 10.3 4.2 4 1 0 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAO82391.1 - 1.2 7.6 6.3 0.53 8.8 2.4 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter Gly-zipper_YMGG PF13441.1 GAO82391.1 - 3.2 7.3 7.3 10 5.7 0.4 2.8 3 0 0 3 3 3 0 YMGG-like Gly-zipper Ank_2 PF12796.2 GAO82392.1 - 1.4e-91 300.9 0.9 3.6e-16 59.2 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82392.1 - 1.2e-73 239.4 3.5 1.5e-07 30.8 0.0 12.2 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 GAO82392.1 - 5e-57 189.3 6.5 3.5e-10 40.1 0.0 10.3 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82392.1 - 5.3e-53 171.6 1.1 5.1e-05 23.1 0.0 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 GAO82392.1 - 1.7e-42 142.4 12.2 1.6e-06 28.1 0.0 9.9 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Glyco_transf_90 PF05686.7 GAO82393.1 - 1.1e-13 50.6 0.9 6e-10 38.3 0.0 3.0 3 0 0 3 3 3 3 Glycosyl transferase family 90 CPSase_L_D2 PF02786.12 GAO82395.1 - 1.2e-57 194.6 0.0 1.7e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAO82395.1 - 2.9e-33 114.0 0.0 6.7e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAO82395.1 - 8.2e-29 99.9 0.0 1.6e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 GAO82395.1 - 2.1e-21 75.9 0.0 1.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 GAO82395.1 - 7.2e-21 74.7 0.1 1.2e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAO82395.1 - 2.3e-10 40.2 0.0 5e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 GAO82395.1 - 4.1e-10 39.1 0.7 1.9e-09 37.0 0.1 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp PF02222.17 GAO82395.1 - 8.2e-07 28.5 0.0 2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAO82395.1 - 5.4e-05 22.7 0.0 0.00028 20.4 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAO82395.1 - 0.00015 21.7 0.0 0.00049 19.9 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 GAO82395.1 - 0.00043 19.5 0.0 0.0011 18.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 GAO82395.1 - 0.0033 16.5 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.1 GAO82395.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp GARS_A PF01071.14 GAO82395.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.1 GAO82395.1 - 0.03 13.9 0.3 0.16 11.6 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like GSH-S_ATP PF02955.11 GAO82395.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Carboxyl_trans PF01039.17 GAO82396.1 - 3.9e-81 272.8 0.0 4.9e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ATP-synt_C PF00137.16 GAO82398.1 - 3e-24 84.6 23.1 3.5e-13 49.2 6.0 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Nucleoplasmin PF03066.10 GAO82398.1 - 0.00097 18.6 4.2 0.0015 18.0 2.9 1.2 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 GAO82398.1 - 0.35 10.4 7.3 0.47 10.0 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 GAO82398.1 - 8 6.6 10.0 18 5.5 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 GAO82398.1 - 9.5 6.6 16.1 23 5.3 11.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 GAO82399.1 - 6e-07 29.1 0.0 1.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat 5_nucleotid_C PF02872.13 GAO82401.1 - 9.5e-38 129.6 0.0 1.8e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Exo_endo_phos PF03372.18 GAO82401.1 - 2.5e-16 60.3 0.4 3.9e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1212 PF06738.7 GAO82402.1 - 8.1e-53 178.7 10.0 6.4e-49 166.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAO82402.1 - 6.5e-28 97.2 9.7 6.5e-28 97.2 6.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) RTC PF01137.16 GAO82403.1 - 3e-44 150.5 0.0 3.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Ank_2 PF12796.2 GAO82404.1 - 4.2e-34 116.7 0.4 6.5e-12 45.6 0.0 4.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82404.1 - 1.1e-18 66.0 11.7 0.00088 18.9 0.0 6.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 GAO82404.1 - 1.1e-17 62.3 3.2 0.022 14.9 0.0 6.9 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAO82404.1 - 3.1e-16 59.3 5.1 2.9e-05 24.4 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO82404.1 - 8.8e-12 44.8 3.8 0.047 13.9 0.0 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) SH3_9 PF14604.1 GAO82406.1 - 1.7e-16 59.4 0.1 3.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 GAO82406.1 - 3.5e-14 52.8 0.5 5.3e-14 52.2 0.3 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAO82406.1 - 7e-14 50.9 0.0 1.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAO82406.1 - 1.2e-12 47.1 0.0 2.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAS PF13851.1 GAO82406.1 - 0.14 11.3 10.9 0.26 10.4 7.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 GAO82406.1 - 0.55 9.7 9.3 1.7 8.1 6.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Mito_fiss_reg PF05308.6 GAO82406.1 - 0.61 9.4 14.3 0.7 9.2 1.4 3.3 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF2439 PF10382.4 GAO82407.1 - 1.5e-28 98.7 0.1 3e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Mcp5_PH PF12814.2 GAO82408.1 - 1.6e-42 144.2 0.1 3.1e-42 143.3 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_23 PF13489.1 GAO82408.1 - 3.7e-14 52.7 0.0 7.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO82408.1 - 3.8e-06 27.2 0.0 2.5e-05 24.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO82408.1 - 6.6e-05 23.3 0.0 0.00056 20.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO82408.1 - 0.0004 20.9 1.2 0.00084 19.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO82408.1 - 0.014 14.9 0.0 0.08 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain zf-C3HC4_3 PF13920.1 GAO82409.1 - 1e-08 34.6 4.6 1.7e-08 34.0 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO82409.1 - 1.5e-08 34.5 10.9 2.3e-08 33.9 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO82409.1 - 7e-07 28.8 11.0 1.1e-06 28.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO82409.1 - 1.5e-06 27.9 6.8 2.3e-06 27.3 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAO82409.1 - 3.5e-06 26.6 9.0 5.5e-06 25.9 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAO82409.1 - 0.0016 18.3 9.1 0.0029 17.4 6.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Cript PF10235.4 GAO82409.1 - 0.013 15.8 1.5 0.037 14.3 1.1 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-RING_UBOX PF13445.1 GAO82409.1 - 0.032 13.9 6.1 0.074 12.7 4.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 GAO82409.1 - 0.1 12.1 2.4 0.19 11.3 1.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 GAO82409.1 - 4 7.6 6.3 10 6.3 4.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DUF3431 PF11913.3 GAO82410.1 - 3.7e-85 284.9 0.3 5.1e-85 284.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MoaF PF10703.4 GAO82410.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F Ku PF02735.11 GAO82411.1 - 3.3e-36 124.5 0.0 5.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAO82411.1 - 9e-35 120.1 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 GAO82411.1 - 5.2e-16 58.9 0.5 1.4e-15 57.5 0.1 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 GAO82411.1 - 1.6e-12 46.6 0.5 3.8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 GAO82411.1 - 0.037 13.5 0.2 0.24 10.9 0.2 2.2 1 1 0 1 1 1 0 HeH/LEM domain Ferrochelatase PF00762.14 GAO82412.1 - 1.7e-93 313.0 0.0 2e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 GAO82413.1 - 2e-28 99.1 34.4 6.6e-27 94.1 15.0 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1751 PF08551.5 GAO82413.1 - 0.015 15.6 2.0 0.015 15.6 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) OATP PF03137.15 GAO82413.1 - 0.11 10.5 3.3 0.092 10.7 0.8 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MRAP PF15183.1 GAO82413.1 - 0.21 11.1 0.1 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family PPR_3 PF13812.1 GAO82414.1 - 9.4e-07 28.6 2.7 0.00055 20.0 0.0 5.3 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAO82414.1 - 1.2e-05 25.1 0.2 0.26 11.2 0.0 4.6 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 GAO82414.1 - 1.2e-05 24.8 0.8 0.92 9.6 0.0 4.8 4 0 0 4 4 4 1 PPR repeat RRM_5 PF13893.1 GAO82414.1 - 0.021 14.6 0.1 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPR_1 PF12854.2 GAO82414.1 - 0.14 11.6 0.0 1.5 8.3 0.0 2.8 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.12 GAO82414.1 - 0.17 11.8 1.7 3.3 7.8 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SE PF08491.5 GAO82415.1 - 1.9e-98 328.6 0.0 2.4e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 GAO82415.1 - 3e-10 39.5 3.0 1.5e-06 27.4 1.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO82415.1 - 4.2e-10 39.2 0.2 6e-09 35.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO82415.1 - 4.5e-05 22.6 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO82415.1 - 0.00036 19.5 1.1 0.0092 14.9 0.6 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAO82415.1 - 0.00053 19.9 0.0 0.00083 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO82415.1 - 0.00097 19.4 0.5 0.0023 18.3 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO82415.1 - 0.0012 17.7 0.1 0.008 15.0 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAO82415.1 - 0.0017 17.2 3.9 0.0027 16.5 1.6 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAO82415.1 - 0.0028 17.6 1.5 0.006 16.5 1.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO82415.1 - 0.016 14.3 0.2 0.036 13.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 GAO82415.1 - 0.021 14.0 0.3 4.1 6.4 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.9 GAO82415.1 - 0.023 13.3 0.3 0.078 11.5 0.2 1.9 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 GAO82415.1 - 0.033 12.6 0.4 0.064 11.7 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 GAO82415.1 - 0.08 12.3 0.3 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAO82415.1 - 0.085 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAO82415.1 - 0.18 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP_assoc PF03828.14 GAO82416.1 - 4.5e-20 71.3 0.1 1.1e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAO82416.1 - 2.9e-06 27.4 0.0 5.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain TruD PF01142.13 GAO82417.1 - 0.088 11.4 1.0 0.13 10.8 0.7 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) DUF914 PF06027.7 GAO82418.1 - 8.6e-104 346.9 17.6 1.2e-103 346.5 12.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAO82418.1 - 0.0012 18.8 11.2 0.0012 18.8 7.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 GAO82418.1 - 9.8 5.8 24.4 0.16 11.6 3.5 2.8 2 1 0 3 3 3 0 Triose-phosphate Transporter family SMK-1 PF04802.10 GAO82419.1 - 7.5e-77 257.2 0.2 1.3e-76 256.4 0.1 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 GAO82419.1 - 0.023 13.7 0.1 0.086 11.9 0.0 1.7 1 1 0 2 2 2 0 Chlamydia virulence protein PGP3-D GalKase_gal_bdg PF10509.4 GAO82419.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature DUF2305 PF10230.4 GAO82420.1 - 2.8e-89 299.0 0.0 3.2e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 GAO82420.1 - 2.2e-05 24.4 0.5 5e-05 23.2 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO82420.1 - 3.7e-05 23.5 1.3 0.00028 20.6 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.5 GAO82420.1 - 0.00021 20.2 0.0 0.00049 19.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) DUF3089 PF11288.3 GAO82420.1 - 0.0029 16.7 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PGAP1 PF07819.8 GAO82420.1 - 0.0068 16.0 1.1 0.02 14.4 0.0 1.8 1 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAO82420.1 - 0.01 15.3 0.6 0.02 14.4 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAO82420.1 - 0.012 15.2 0.4 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Lipase (class 3) LCAT PF02450.10 GAO82420.1 - 0.016 14.2 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1057 PF06342.7 GAO82420.1 - 0.019 13.8 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 GAO82420.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 GAO82420.1 - 0.036 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 GAO82420.1 - 0.042 14.0 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Thioesterase domain DCP1 PF06058.8 GAO82421.1 - 6.1e-17 61.8 0.1 9.2e-16 58.0 0.0 2.3 2 1 0 2 2 2 1 Dcp1-like decapping family DUF664 PF04978.7 GAO82421.1 - 0.022 15.0 0.3 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF664) Exo_endo_phos PF03372.18 GAO82422.1 - 1.3e-19 71.0 0.1 1.9e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ycf4 PF02392.11 GAO82422.1 - 0.0072 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Ycf4 PapD-like PF14874.1 GAO82422.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like RhoGAP PF00620.22 GAO82422.1 - 0.21 11.1 0.6 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 RhoGAP domain DUF2636 PF11120.3 GAO82423.1 - 0.12 11.8 0.7 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Cob_adeno_trans PF01923.13 GAO82423.1 - 0.15 11.8 1.5 0.63 9.8 0.1 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3373 PF11853.3 GAO82423.1 - 0.26 9.7 0.1 0.36 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3090 PF11290.3 GAO82423.1 - 0.29 10.5 1.7 0.26 10.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) OmpH PF03938.9 GAO82423.1 - 0.31 10.9 4.9 0.55 10.1 3.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ScpA_ScpB PF02616.9 GAO82423.1 - 1.2 8.6 4.0 0.22 11.0 0.4 1.4 2 0 0 2 2 2 0 ScpA/B protein STE3 PF02076.10 GAO82424.1 - 1.9e-106 355.2 19.8 2.3e-106 355.0 13.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.20 GAO82425.1 - 3.4e-16 58.9 0.0 4.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4203 PF13886.1 GAO82426.1 - 5.8e-44 150.0 22.4 7.5e-44 149.7 15.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 GAO82426.1 - 4.6e-33 113.5 0.0 1e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.16 GAO82427.1 - 7.4e-85 284.2 0.0 9.2e-85 283.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAO82427.1 - 0.00013 21.7 0.1 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 GAO82427.1 - 0.013 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Myb_DNA-bind_6 PF13921.1 GAO82428.1 - 3.4e-05 23.8 0.6 6.8e-05 22.8 0.2 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO82428.1 - 0.045 13.8 0.2 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain ORC6 PF05460.8 GAO82428.1 - 2.1 7.3 12.3 2.9 6.8 8.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.20 GAO82429.1 - 9.9e-60 201.8 0.0 2.5e-58 197.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82429.1 - 4.6e-28 97.9 0.0 4.8e-26 91.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO82429.1 - 2.7e-06 27.2 0.1 1.6e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family FHA PF00498.21 GAO82429.1 - 8.4e-06 25.8 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAO82429.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO82429.1 - 0.0034 16.4 0.0 0.0094 15.0 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO82429.1 - 0.0071 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 GAO82429.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ank_5 PF13857.1 GAO82430.1 - 2.4e-07 30.7 0.0 5.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 GAO82430.1 - 0.00037 20.1 0.1 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 GAO82430.1 - 0.0039 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82430.1 - 0.0089 16.1 0.0 0.095 12.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 GAO82430.1 - 0.013 15.7 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 GAO82430.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ABC_membrane PF00664.18 GAO82431.1 - 4.9e-74 249.2 30.0 2.8e-39 135.1 7.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO82431.1 - 2.6e-50 170.2 1.3 2.3e-29 102.4 0.0 3.1 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.14 GAO82431.1 - 3.9e-09 36.0 5.0 6.7e-05 22.2 0.4 4.6 1 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAO82431.1 - 3.7e-06 26.4 0.0 0.036 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO82431.1 - 9.2e-06 25.7 0.6 0.038 13.9 0.6 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 GAO82431.1 - 0.00019 21.3 0.1 0.48 10.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAO82431.1 - 0.00046 19.6 0.1 1.4 8.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAO82431.1 - 0.001 18.2 0.1 0.35 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 GAO82431.1 - 0.0047 16.9 2.4 14 5.5 0.0 4.7 5 0 0 5 5 5 0 AAA domain AAA_23 PF13476.1 GAO82431.1 - 0.0099 16.2 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAO82431.1 - 0.023 14.5 2.1 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.13 GAO82431.1 - 0.026 13.9 0.0 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 GAO82431.1 - 0.031 14.0 1.1 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 GAO82431.1 - 0.033 13.6 1.7 6.9 5.9 0.3 2.6 2 1 0 2 2 2 0 AAA-like domain Miro PF08477.8 GAO82431.1 - 0.051 14.0 2.2 5.4 7.5 0.2 2.7 2 0 0 2 2 2 0 Miro-like protein DUF2841 PF11001.3 GAO82432.1 - 8.1e-51 171.1 0.2 1.2e-50 170.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) BLYB PF05289.6 GAO82432.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein SAC3_GANP PF03399.11 GAO82433.1 - 5.3e-56 189.4 0.2 7.4e-56 188.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAO82433.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 CN_hydrolase PF00795.17 GAO82434.1 - 1.1e-12 47.7 0.0 4.3e-11 42.5 0.0 2.1 1 1 0 2 2 2 2 Carbon-nitrogen hydrolase HLH PF00010.21 GAO82435.1 - 1.2e-13 50.4 1.7 2.7e-13 49.3 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DPBB_1 PF03330.13 GAO82436.1 - 3.3e-12 46.2 0.1 1.1e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAO82436.1 - 0.0013 18.6 0.3 0.0024 17.8 0.2 1.5 1 0 0 1 1 1 1 Cerato-platanin BNR PF02012.15 GAO82436.1 - 0.029 14.1 0.5 0.029 14.1 0.4 2.5 3 0 0 3 3 3 0 BNR/Asp-box repeat Pollen_allerg_1 PF01357.16 GAO82436.1 - 0.052 13.3 0.3 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Pollen allergen Mo-co_dimer PF03404.11 GAO82436.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF605 PF04652.11 GAO82436.1 - 2.5 7.3 13.3 3.5 6.9 9.2 1.1 1 0 0 1 1 1 0 Vta1 like Sec8_exocyst PF04048.9 GAO82437.1 - 7e-53 178.0 1.6 2e-52 176.6 1.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 GAO82437.1 - 1.2e-09 37.5 0.9 2.4e-09 36.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 GAO82437.1 - 0.0023 16.1 1.0 0.0037 15.5 0.7 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 GAO82437.1 - 0.012 15.3 0.9 0.025 14.3 0.6 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF3829 PF12889.2 GAO82437.1 - 0.021 14.0 0.2 0.044 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Vps51 PF08700.6 GAO82437.1 - 7.7 6.4 7.9 0.74 9.7 0.2 3.0 3 0 0 3 3 3 0 Vps51/Vps67 Peptidase_M24 PF00557.19 GAO82438.1 - 8.2e-42 143.1 0.0 1.2e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAO82438.1 - 5.5e-09 36.6 0.0 7.3e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain IBN_N PF03810.14 GAO82439.1 - 0.0055 16.5 0.3 0.035 14.0 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain MUG113 PF13455.1 GAO82440.1 - 4.3e-36 123.2 0.6 1.2e-35 121.7 0.4 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 GAO82440.1 - 2.4e-26 92.0 0.1 7.2e-26 90.5 0.1 1.8 1 0 0 1 1 1 1 T5orf172 domain zf-primase PF09329.6 GAO82440.1 - 1.8 8.2 4.7 1.8 8.2 0.1 2.8 3 1 0 3 3 3 0 Primase zinc finger Plasmodium_Vir PF05795.6 GAO82441.1 - 0.076 12.2 0.0 0.15 11.2 0.1 1.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ABC2_membrane_4 PF12730.2 GAO82441.1 - 0.42 9.7 14.9 0.54 9.3 10.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SOR_SNZ PF01680.12 GAO82442.1 - 1.3e-110 367.8 6.8 2.2e-110 367.1 4.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 GAO82442.1 - 4e-09 35.9 6.2 1.2e-06 27.7 0.0 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAO82442.1 - 0.00032 20.0 0.3 0.025 13.8 0.0 3.0 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 GAO82442.1 - 0.00075 18.4 0.6 0.28 9.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 GAO82442.1 - 0.0011 18.1 0.0 0.027 13.5 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 GAO82442.1 - 0.0083 15.1 1.4 0.11 11.3 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 GAO82442.1 - 0.86 8.6 9.8 0.049 12.7 0.7 2.4 2 2 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 GAO82443.1 - 5.4e-11 42.6 3.3 2.8e-10 40.3 2.3 2.1 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.9 GAO82444.1 - 3.7e-103 344.8 0.0 4.5e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Drc1-Sld2 PF11719.3 GAO82444.1 - 0.041 12.9 15.8 0.0086 15.2 8.7 1.5 2 0 0 2 2 2 0 DNA replication and checkpoint protein ArgJ PF01960.13 GAO82445.1 - 2.1e-147 490.5 0.0 2.4e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 GAO82446.1 - 1.4e-97 326.6 6.8 1.8e-97 326.3 4.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAO82446.1 - 2.7e-18 65.1 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p ABC_tran PF00005.22 GAO82448.1 - 1.2e-48 164.8 0.0 6.9e-32 110.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO82448.1 - 4.5e-33 114.8 18.5 3.4e-21 75.8 6.4 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO82448.1 - 1.2e-09 37.7 0.0 0.015 14.5 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO82448.1 - 3.9e-07 30.3 0.1 1.5 8.7 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAO82448.1 - 1.6e-06 28.6 0.0 0.0012 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO82448.1 - 2.2e-05 23.9 0.0 0.075 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO82448.1 - 4.4e-05 22.9 0.0 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 GAO82448.1 - 0.00016 21.5 0.3 0.13 12.0 0.0 2.8 3 0 0 3 3 2 1 Domain of unknown function DUF87 T2SE PF00437.15 GAO82448.1 - 0.00036 19.5 0.0 0.36 9.6 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAO82448.1 - 0.00042 20.2 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 GAO82448.1 - 0.001 18.5 0.8 0.56 9.5 0.1 3.1 2 1 1 3 3 3 1 AAA-like domain AAA_22 PF13401.1 GAO82448.1 - 0.0012 19.0 0.1 2.2 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO82448.1 - 0.0013 18.2 0.0 0.7 9.3 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF258 PF03193.11 GAO82448.1 - 0.0074 15.4 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO82448.1 - 0.01 16.3 0.0 7.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 GAO82448.1 - 0.013 15.4 5.8 0.27 11.2 1.0 3.4 3 1 0 3 3 2 0 AAA ATPase domain Zeta_toxin PF06414.7 GAO82448.1 - 0.023 13.7 0.1 7.8 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 GAO82448.1 - 0.024 15.4 0.0 0.97 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 GAO82448.1 - 0.037 13.9 0.8 6.5 6.7 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 GAO82448.1 - 0.05 13.7 0.0 31 4.7 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 GAO82448.1 - 0.081 12.7 0.1 24 4.7 0.0 3.1 3 0 0 3 3 3 0 Dynamin family DUF2075 PF09848.4 GAO82448.1 - 0.089 11.7 0.1 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 GAO82448.1 - 0.2 11.0 3.3 3.1 7.1 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein MobB PF03205.9 GAO82448.1 - 0.22 11.2 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cyclin_N PF00134.18 GAO82449.1 - 0.0065 16.0 0.0 0.03 13.9 0.0 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Autophagy_N PF03986.8 GAO82450.1 - 8.3e-51 171.5 0.1 1.5e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 GAO82450.1 - 3.1e-22 78.5 0.1 7.1e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 GAO82450.1 - 2e-14 52.3 0.5 3.4e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal IFT43 PF15305.1 GAO82450.1 - 0.034 14.1 1.2 0.066 13.2 0.8 1.4 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Nucleoplasmin PF03066.10 GAO82450.1 - 3.1 7.3 6.6 5.5 6.4 4.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF605 PF04652.11 GAO82451.1 - 3 7.1 17.5 3.8 6.8 12.1 1.2 1 0 0 1 1 1 0 Vta1 like SpecificRecomb PF10136.4 GAO82452.1 - 0.16 9.9 0.0 0.24 9.4 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase MerR PF00376.18 GAO82453.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein Glycos_transf_2 PF00535.21 GAO82454.1 - 8.6e-20 71.0 0.0 3.3e-10 39.8 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAO82454.1 - 2e-07 31.0 0.6 0.027 14.2 0.1 3.9 2 2 2 4 4 4 2 Glycosyltransferase like family 2 OSTMP1 PF09777.4 GAO82454.1 - 0.061 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor LrgB PF04172.11 GAO82454.1 - 0.069 12.2 0.1 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 LrgB-like family EST1_DNA_bind PF10373.4 GAO82455.1 - 7.5e-11 41.7 0.2 1.7e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain NUDIX PF00293.23 GAO82457.1 - 9.5e-07 28.5 0.0 3.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 GAO82458.1 - 1.3e-16 60.4 0.0 2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 GAO82460.1 - 2.6e-18 66.8 0.0 3.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO82460.1 - 9.8e-09 34.8 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO82460.1 - 1.1e-08 35.7 0.1 2.6e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 GAO82460.1 - 7.4e-06 25.7 0.0 0.00013 21.7 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.2 GAO82460.1 - 0.0018 18.5 0.0 0.0024 18.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hexokinase_1 PF00349.16 GAO82460.1 - 0.072 12.4 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Hexokinase DUF1456 PF07308.8 GAO82460.1 - 0.086 12.8 1.0 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Init_tRNA_PT PF04179.7 GAO82461.1 - 6.7e-143 476.8 0.0 3.3e-109 365.7 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase Herpes_gE PF02480.11 GAO82461.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Aldo_ket_red PF00248.16 GAO82462.1 - 1.2e-45 155.5 0.0 1.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CH PF00307.26 GAO82463.1 - 2.9e-34 117.3 0.0 5e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 GAO82463.1 - 2.3e-28 97.9 0.1 6.3e-28 96.5 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 GAO82463.1 - 7.1e-10 38.3 1.8 7.5e-07 28.7 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 GAO82463.1 - 0.0019 17.9 1.6 0.0046 16.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 GAO82463.1 - 0.0035 16.5 0.1 0.033 13.4 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF761 PF05553.6 GAO82463.1 - 0.0053 16.0 1.5 0.015 14.6 1.0 1.8 1 0 0 1 1 1 1 Cotton fibre expressed protein EF-hand_8 PF13833.1 GAO82463.1 - 0.01 15.4 0.0 0.04 13.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair Thermopsin PF05317.6 GAO82463.1 - 0.078 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Thermopsin Spectrin PF00435.16 GAO82463.1 - 0.2 11.9 7.9 0.88 9.8 0.0 3.1 3 0 0 3 3 3 0 Spectrin repeat RRM_1 PF00076.17 GAO82464.1 - 5e-17 61.2 0.0 7.4e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82464.1 - 7.7e-12 45.0 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAO82464.1 - 5.9e-07 29.8 3.7 5.9e-07 29.8 2.6 2.5 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 GAO82464.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAO82465.1 - 1.2e-33 113.7 9.7 1e-10 41.0 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAO82465.1 - 0.041 12.6 0.4 1.2 7.8 0.2 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Me-amine-dh_H PF06433.6 GAO82465.1 - 0.06 11.9 0.0 4.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.3 GAO82465.1 - 0.11 10.5 0.5 3.9 5.4 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 GAO82465.1 - 0.77 9.1 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PUL PF08324.6 GAO82466.1 - 8.7e-58 195.2 0.0 1.2e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 GAO82466.1 - 4.3e-44 149.2 0.3 8.1e-44 148.3 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 GAO82466.1 - 3.5e-38 128.1 15.6 2.9e-07 30.0 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAO82466.1 - 0.0014 18.4 0.1 0.17 11.6 0.0 3.4 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region GCV_T_C PF08669.6 GAO82466.1 - 0.013 15.4 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain YjeF_N PF03853.10 GAO82467.1 - 1.5e-33 115.8 0.0 2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 GAO82468.1 - 3.2e-27 94.0 0.1 4e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 GAO82469.1 - 2.1e-16 59.3 0.0 5.5e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82469.1 - 3.8e-10 39.5 0.0 1.1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 GAO82470.1 - 2.9e-56 190.1 0.9 4.6e-56 189.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Cohesin_HEAT PF12765.2 GAO82470.1 - 0.052 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Response_reg PF00072.19 GAO82471.1 - 4.3e-20 71.7 0.0 3.8e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.9 GAO82472.1 - 7.8e-20 70.1 14.8 1.5e-19 69.2 0.9 3.6 3 1 1 4 4 4 2 PQ loop repeat DUF2270 PF10028.4 GAO82472.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Vpu PF00558.14 GAO82472.1 - 0.33 10.5 1.6 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Vpu protein SH3_1 PF00018.23 GAO82473.1 - 1.9e-09 36.7 0.9 2.4e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 GAO82473.1 - 1.6e-07 30.6 0.0 3.9e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAO82473.1 - 4.6e-07 29.3 0.0 9e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LMP1 PF05297.6 GAO82473.1 - 0.12 11.2 0.8 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4149 PF13664.1 GAO82473.1 - 0.33 11.0 5.2 0.71 9.9 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Dispanin PF04505.7 GAO82473.1 - 1.4 8.4 7.4 0.091 12.3 0.9 2.2 2 1 0 2 2 2 0 Interferon-induced transmembrane protein 7tm_6 PF02949.15 GAO82473.1 - 1.6 7.4 11.4 0.46 9.2 1.8 2.1 1 1 1 2 2 2 0 7tm Odorant receptor DUF1129 PF06570.6 GAO82473.1 - 3.4 6.9 10.2 0.13 11.5 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2156 PF09924.4 GAO82474.1 - 7.5e-32 110.3 0.0 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) UBA_4 PF14555.1 GAO82475.1 - 2.3e-10 39.8 0.0 6.7e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain HsbA PF12296.3 GAO82475.1 - 0.011 15.5 0.0 0.039 13.7 0.0 2.0 1 0 0 1 1 1 0 Hydrophobic surface binding protein A SET PF00856.23 GAO82476.1 - 5.2e-15 56.1 0.0 6.6e-14 52.5 0.0 2.3 1 1 0 1 1 1 1 SET domain AMP-binding PF00501.23 GAO82477.1 - 2.1e-76 257.0 0.0 2.5e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO82477.1 - 6.6e-19 68.6 0.0 1.9e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 GAO82478.1 - 3.6e-52 177.0 0.0 5.9e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2052 PF09747.4 GAO82478.1 - 2.8e-37 128.3 8.7 6.7e-37 127.1 6.0 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pkinase_Tyr PF07714.12 GAO82478.1 - 7.2e-24 84.2 0.0 2e-23 82.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO82478.1 - 0.076 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Kinase-like Spermine_synth PF01564.12 GAO82479.1 - 4.3e-09 35.6 0.0 7.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 GAO82479.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAO82479.1 - 0.046 14.1 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAO82479.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DLIC PF05783.6 GAO82480.1 - 1.7e-35 122.6 0.2 1.9e-32 112.5 0.0 3.3 4 0 0 4 4 4 2 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 GAO82480.1 - 0.24 11.0 2.2 0.59 9.7 1.5 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif RRM_1 PF00076.17 GAO82481.1 - 9.2e-20 70.0 0.0 1.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82481.1 - 2.3e-13 49.9 0.0 4.2e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82481.1 - 1.7e-07 30.9 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAO82482.1 - 1.3e-08 34.3 0.1 0.004 16.9 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 GAO82482.1 - 0.0026 15.6 0.0 0.0032 15.3 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Nbas_N PF15492.1 GAO82482.1 - 0.027 13.5 0.0 0.71 8.9 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 GAO82483.1 - 8.5e-89 297.2 2.2 1.5e-77 260.3 0.0 2.4 2 1 1 3 3 3 2 Septin AAA_17 PF13207.1 GAO82483.1 - 0.0018 19.1 1.0 0.18 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAO82483.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAO82483.1 - 0.039 13.1 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 GAO82483.1 - 0.09 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 GAO82483.1 - 0.21 11.7 0.9 0.44 10.6 0.1 2.1 2 2 0 2 2 2 0 AAA domain DUF3653 PF12375.3 GAO82483.1 - 0.29 11.3 2.4 6.1 7.1 0.9 2.7 2 1 0 2 2 2 0 Phage protein Dynamin_N PF00350.18 GAO82483.1 - 0.36 10.6 1.7 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 GAO82483.1 - 0.43 10.8 1.8 2.7 8.2 1.3 2.4 1 1 0 1 1 1 0 ABC transporter CNH PF00780.17 GAO82484.1 - 1.3e-83 280.5 0.0 7.8e-83 278.0 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 GAO82484.1 - 1.6e-42 144.6 0.0 4.9e-42 143.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 GAO82484.1 - 6.7e-39 133.6 0.0 1.4e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 GAO82484.1 - 1.2e-14 53.8 0.0 3.5e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YorP PF09629.5 GAO82484.1 - 0.18 11.7 0.1 8 6.5 0.0 2.5 2 0 0 2 2 2 0 YorP protein ATP-synt_C PF00137.16 GAO82485.1 - 1.9e-25 88.5 29.8 5.4e-14 51.8 6.4 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 GAO82486.1 - 1e-64 218.2 0.0 1.3e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82486.1 - 6.8e-37 126.9 0.0 8.9e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO82486.1 - 0.00018 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO82486.1 - 0.00032 20.5 0.2 0.021 14.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO82486.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.10 GAO82487.1 - 7.8e-13 48.7 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_43 PF04616.9 GAO82488.1 - 1.9e-36 125.6 0.3 2.5e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_1 PF00561.15 GAO82489.1 - 8.4e-19 68.0 0.0 6.1e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO82489.1 - 2.6e-10 40.6 0.4 6.1e-09 36.0 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO82489.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ThiF PF00899.16 GAO82490.1 - 6.7e-35 119.8 0.0 1.3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 GAO82490.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 GAO82490.1 - 0.033 13.6 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 GAO82490.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_17 PF00332.13 GAO82490.1 - 0.067 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Kinocilin PF15033.1 GAO82490.1 - 0.075 12.5 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinocilin protein Metallophos PF00149.23 GAO82491.1 - 6.6e-13 48.5 1.0 9.4e-12 44.7 0.7 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO82491.1 - 6.3e-07 29.3 0.3 1.1e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LCCL PF03815.14 GAO82492.1 - 1.1e-14 54.1 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 LCCL domain TctB PF07331.6 GAO82492.1 - 0.0093 15.6 2.8 0.0093 15.6 2.0 2.3 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family FUSC PF04632.7 GAO82492.1 - 0.4 9.0 14.1 0.92 7.8 3.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family MARVEL PF01284.18 GAO82493.1 - 5.7e-22 78.0 15.3 7.1e-22 77.7 10.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF308 PF03729.8 GAO82493.1 - 0.13 12.3 18.7 1.5 8.8 0.5 3.1 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) GH114_assoc PF14741.1 GAO82493.1 - 0.54 9.9 2.7 0.74 9.5 1.9 1.2 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Polysacc_synt_C PF14667.1 GAO82493.1 - 0.89 9.3 8.2 0.79 9.5 3.5 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Nse4_C PF08743.5 GAO82494.1 - 3.7e-36 123.0 0.0 1e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 GAO82494.1 - 6.4e-20 70.7 0.1 1.6e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.1 GAO82494.1 - 2.2e-16 59.8 0.0 5e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Pox_A_type_inc PF04508.7 GAO82494.1 - 0.15 11.9 7.2 0.62 9.9 5.0 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_S64 PF08192.6 GAO82494.1 - 1.8 6.8 8.3 0.18 10.1 2.7 1.5 2 0 0 2 2 2 0 Peptidase family S64 PI3Ka PF00613.15 GAO82495.1 - 4.1e-60 202.1 0.1 6.9e-60 201.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAO82495.1 - 2e-42 145.2 0.0 4.7e-41 140.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAO82495.1 - 7.4e-27 93.8 0.0 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 MMR_HSR1 PF01926.18 GAO82496.1 - 9.5e-14 51.3 0.0 3.4e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAO82496.1 - 5.6e-06 25.6 0.0 9.4e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 GAO82496.1 - 3e-05 23.3 0.1 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 GAO82496.1 - 0.00051 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin MobB PF03205.9 GAO82496.1 - 0.00058 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 GAO82496.1 - 0.0018 17.3 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 GAO82496.1 - 0.0056 16.1 0.0 0.29 10.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 GAO82496.1 - 0.0068 16.9 0.1 0.1 13.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 GAO82496.1 - 0.0072 15.8 0.0 0.35 10.3 0.0 2.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 GAO82496.1 - 0.028 14.7 0.1 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAO82496.1 - 0.033 14.0 0.3 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Dynamin family AAA_17 PF13207.1 GAO82496.1 - 0.041 14.7 0.1 0.14 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 GAO82496.1 - 0.041 14.0 0.1 0.53 10.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain ArgK PF03308.11 GAO82496.1 - 0.058 12.1 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 GAO82496.1 - 0.069 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 GAO82496.1 - 0.15 11.3 0.0 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 GAO82496.1 - 0.15 11.2 0.0 0.36 10.0 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Isy1 PF06246.7 GAO82497.1 - 1.3e-87 293.4 0.4 1.7e-87 293.0 0.3 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.16 GAO82498.1 - 5.4e-249 827.8 0.0 1.9e-248 826.1 0.0 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAO82498.1 - 2.3e-37 128.2 299.1 8.8e-25 86.6 95.8 6.0 1 1 4 5 5 5 5 Myosin tail Myosin_N PF02736.14 GAO82498.1 - 0.0093 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 GAO82498.1 - 0.071 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 GAO82498.1 - 0.7 9.0 83.7 0.037 13.2 2.8 9.6 3 2 6 10 10 10 0 Reovirus sigma C capsid protein zf-C3H1 PF10650.4 GAO82499.1 - 3e-12 45.7 0.7 4.7e-12 45.1 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Spc7 PF08317.6 GAO82499.1 - 0.77 8.3 12.0 1.1 7.8 3.6 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-RING_5 PF14634.1 GAO82500.1 - 1.2 8.9 12.4 5.2 6.8 8.7 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-DHHC PF01529.15 GAO82501.1 - 5.2e-25 87.8 4.4 1.6e-24 86.2 3.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transformer PF06495.6 GAO82501.1 - 0.025 14.4 5.9 1.9 8.3 1.6 2.5 2 0 0 2 2 2 0 Fruit fly transformer protein Lig_chan PF00060.21 GAO82501.1 - 0.62 9.7 2.3 1.5 8.5 1.1 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel Glyco_hydro_17 PF00332.13 GAO82504.1 - 2.1e-06 27.0 4.0 8.5e-05 21.7 0.8 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Wzz PF02706.10 GAO82504.1 - 5.3 6.8 6.0 2.7 7.8 0.3 2.3 2 1 0 2 2 2 0 Chain length determinant protein SRR1 PF07985.7 GAO82505.1 - 6.8e-17 61.1 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 GAO82505.1 - 0.011 15.7 0.4 0.021 14.8 0.3 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) CATSPERB PF15149.1 GAO82506.1 - 0.0067 14.6 0.0 0.0093 14.2 0.0 1.1 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit beta protein family Abhydrolase_6 PF12697.2 GAO82507.1 - 2.6e-24 86.3 1.2 6e-24 85.1 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO82507.1 - 1.3e-09 38.0 0.1 5.6e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO82507.1 - 1e-07 31.7 0.0 5.2e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO82507.1 - 3.3e-07 30.0 0.0 9.5e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 GAO82507.1 - 0.00037 19.9 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Putative esterase eIF-5a PF01287.15 GAO82508.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF4541 PF15074.1 GAO82508.1 - 0.06 13.9 3.2 1 9.9 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) PHD PF00628.24 GAO82509.1 - 1.1e-09 37.7 2.2 2.8e-09 36.5 1.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAO82509.1 - 0.026 13.8 2.4 0.042 13.1 1.7 1.4 1 0 0 1 1 1 0 PHD-finger FAM70 PF14967.1 GAO82510.1 - 3.8 6.6 4.4 6.8 5.8 3.0 1.3 1 0 0 1 1 1 0 FAM70 protein MARVEL PF01284.18 GAO82511.1 - 4.6e-09 36.2 4.6 6.7e-09 35.7 3.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain Keratin_assoc PF09775.4 GAO82511.1 - 0.0066 16.0 0.6 0.02 14.4 0.2 1.8 2 0 0 2 2 2 1 Keratinocyte-associated protein 2 DUF1752 PF08550.5 GAO82512.1 - 3.8e-05 23.1 0.2 9.4e-05 21.9 0.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Aconitase PF00330.15 GAO82513.1 - 3.7e-72 243.2 0.8 8.6e-69 232.2 0.6 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAO82513.1 - 1.5e-17 63.9 0.0 3.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain adh_short_C2 PF13561.1 GAO82514.1 - 3.9e-29 102.1 0.0 5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82514.1 - 2.7e-23 82.7 0.4 3.6e-23 82.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82514.1 - 5.2e-14 52.3 0.3 8e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO82514.1 - 4e-05 23.1 0.2 0.00018 21.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO82514.1 - 0.033 13.1 0.0 0.065 12.1 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein CPSase_L_D2 PF02786.12 GAO82515.1 - 5.8e-76 254.4 0.0 8.8e-76 253.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAO82515.1 - 1.8e-36 124.3 0.0 4.9e-36 122.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAO82515.1 - 5.7e-35 119.7 0.0 1.6e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAO82515.1 - 1.3e-18 67.3 0.0 3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAO82515.1 - 3.9e-18 64.8 1.2 3.9e-18 64.8 0.8 2.1 2 0 0 2 2 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAO82515.1 - 2.4e-12 46.2 0.0 6.5e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAO82515.1 - 2.7e-10 39.9 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAO82515.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAO82515.1 - 2.9e-06 26.8 0.8 0.0012 18.4 0.0 3.1 2 1 1 3 3 3 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 GAO82515.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 GAO82515.1 - 0.00038 20.7 0.0 0.63 10.4 0.0 3.1 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 GAO82515.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 GAO82515.1 - 0.0012 18.3 0.0 0.0059 16.1 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 GAO82515.1 - 0.0056 16.3 0.3 0.06 13.0 0.1 2.2 2 0 0 2 2 2 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.1 GAO82515.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD PF00529.15 GAO82515.1 - 0.31 10.2 3.0 13 4.9 0.0 2.9 2 1 1 3 3 3 0 HlyD family secretion protein Acyl-CoA_dh_1 PF00441.19 GAO82517.1 - 1.8e-41 141.7 0.8 3.5e-41 140.7 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO82517.1 - 2.2e-33 115.1 0.2 4.4e-33 114.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAO82517.1 - 2.7e-21 74.8 0.5 5.8e-21 73.7 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO82517.1 - 6.5e-16 58.7 0.1 1.2e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAO82517.1 - 0.00087 18.7 0.3 0.0048 16.3 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 GAO82518.1 - 9.8e-145 482.6 0.2 1.2e-144 482.3 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 GAO82518.1 - 0.041 13.0 0.3 1.5 7.9 0.0 2.5 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.17 GAO82519.1 - 6e-43 146.0 0.0 7.7e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO82519.1 - 6.2e-15 55.7 0.0 9.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAO82519.1 - 1.4e-05 24.6 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 GAO82519.1 - 2e-05 23.9 0.0 2.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Abhydro_lipase PF04083.11 GAO82520.1 - 9.2e-22 76.1 0.1 8.3e-21 73.1 0.0 2.2 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAO82520.1 - 3.6e-18 65.9 0.3 5.1e-18 65.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO82520.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO82520.1 - 0.00024 20.8 0.0 0.0018 18.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 GAO82520.1 - 0.012 15.1 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pet191_N PF10203.4 GAO82521.1 - 7.7e-17 61.1 0.4 9.9e-17 60.7 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DDOST_48kD PF03345.9 GAO82522.1 - 6.6e-173 575.0 0.0 7.5e-173 574.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta IMS PF00817.15 GAO82525.1 - 3.2e-36 124.3 0.0 1.9e-35 121.8 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAO82525.1 - 1.9e-14 53.6 0.0 4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain WSC PF01822.14 GAO82527.1 - 5.4e-11 42.2 10.5 5.4e-11 42.2 7.3 2.3 2 0 0 2 2 2 1 WSC domain Dicty_REP PF05086.7 GAO82527.1 - 6.7e-05 20.8 0.8 7.7e-05 20.6 0.5 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein MerE PF05052.7 GAO82527.1 - 0.048 13.6 0.8 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 MerE protein Ank_2 PF12796.2 GAO82528.1 - 8.1e-62 205.5 2.3 1.9e-12 47.3 0.0 6.1 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82528.1 - 7e-42 139.2 12.3 4.9e-05 22.9 0.0 13.0 12 1 1 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 GAO82528.1 - 2.3e-41 139.4 5.4 4e-06 27.1 0.0 9.4 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82528.1 - 4.4e-41 134.7 8.0 0.0039 17.2 0.0 13.4 12 2 1 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 GAO82528.1 - 4.8e-36 121.9 8.2 6.8e-07 29.3 0.0 9.5 4 3 7 11 11 11 10 Ankyrin repeats (many copies) F-box PF00646.28 GAO82528.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO82528.1 - 0.0044 16.7 0.3 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 F-box-like Phage_30_3 PF08010.6 GAO82529.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 DUF3445 PF11927.3 GAO82530.1 - 1.5e-76 257.0 0.0 2e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PRP38 PF03371.10 GAO82531.1 - 5e-68 228.1 0.0 6e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 GAO82533.1 - 2.8e-21 74.5 1.7 0.011 15.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat CPSF_A PF03178.10 GAO82533.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 CPSF A subunit region Pkinase PF00069.20 GAO82534.1 - 4.7e-51 173.4 0.0 7.4e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AAA_12 PF13087.1 GAO82534.1 - 8.7e-38 129.7 0.2 1.5e-37 128.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAO82534.1 - 4.1e-21 75.6 0.2 2.7e-20 72.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.12 GAO82534.1 - 5.7e-19 68.2 0.0 9.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_19 PF13245.1 GAO82534.1 - 1.2e-07 31.3 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAO82534.1 - 2.2e-06 27.4 0.0 7.6e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 GAO82534.1 - 5.2e-06 26.1 0.0 0.004 16.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 GAO82534.1 - 0.00067 19.1 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAO82534.1 - 0.00073 19.4 0.0 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 GAO82534.1 - 0.0028 16.9 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 GAO82534.1 - 0.0072 15.6 0.0 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ParA PF10609.4 GAO82534.1 - 0.0099 15.7 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF2075 PF09848.4 GAO82534.1 - 0.01 14.8 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Kdo PF06293.9 GAO82534.1 - 0.026 13.5 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UvrD_C_2 PF13538.1 GAO82534.1 - 0.05 13.7 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.12 GAO82534.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Aa_trans PF01490.13 GAO82535.1 - 9.6e-28 96.7 30.6 1.1e-27 96.5 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 GAO82535.1 - 2.6e-06 26.2 40.4 0.00031 19.4 28.0 2.0 1 1 0 1 1 1 1 Amino acid permease Polysacc_deac_1 PF01522.16 GAO82536.1 - 1.1e-22 79.9 0.0 2.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAO82536.1 - 0.065 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4110 PF13422.1 GAO82536.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Amidase PF01425.16 GAO82537.1 - 1.7e-79 267.7 0.5 4.7e-79 266.2 0.4 1.6 1 1 0 1 1 1 1 Amidase adh_short_C2 PF13561.1 GAO82538.1 - 2.3e-26 93.0 0.0 2.7e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82538.1 - 7.3e-23 81.3 0.1 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82538.1 - 1.1e-06 28.3 0.1 2.2e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAO82538.1 - 0.00014 21.3 0.1 0.00026 20.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAO82538.1 - 0.00048 19.8 0.1 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO82538.1 - 0.0013 17.6 0.0 0.0028 16.6 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 GAO82538.1 - 0.051 13.4 0.9 0.12 12.1 0.5 1.7 1 1 0 1 1 1 0 ThiF family Fungal_trans PF04082.13 GAO82539.1 - 2e-12 46.5 1.1 2e-12 46.5 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO82539.1 - 4.6e-08 32.9 10.7 4.5e-05 23.5 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO82539.1 - 2.1e-06 27.6 10.5 0.00068 19.7 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO82539.1 - 7.8e-06 25.9 2.2 7.8e-06 25.9 1.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAO82539.1 - 0.027 14.6 0.5 0.027 14.6 0.4 2.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.15 GAO82539.1 - 0.18 11.5 1.4 0.33 10.6 0.9 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Ferritin_2 PF13668.1 GAO82540.1 - 1.3e-14 54.3 1.8 1.6e-14 53.9 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain ABC_tran PF00005.22 GAO82541.1 - 4.8e-54 182.3 0.0 1.6e-31 109.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO82541.1 - 1.4e-44 152.6 29.2 3.9e-27 95.3 1.6 4.0 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 GAO82541.1 - 1.7e-09 38.0 0.1 0.012 15.6 0.0 3.7 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 GAO82541.1 - 3.9e-07 29.5 6.3 0.0064 15.7 0.3 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAO82541.1 - 7.5e-07 29.6 0.2 0.00056 20.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO82541.1 - 7.7e-06 25.4 0.1 0.15 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO82541.1 - 8.4e-05 22.7 0.7 6.7 6.8 0.1 3.5 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 GAO82541.1 - 0.00018 20.5 0.0 0.0053 15.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 GAO82541.1 - 0.00018 20.9 0.8 0.36 10.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 GAO82541.1 - 0.0002 20.9 0.6 1.3 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 GAO82541.1 - 0.00023 21.1 1.7 0.85 9.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 GAO82541.1 - 0.00027 20.8 0.0 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAO82541.1 - 0.00035 19.7 1.4 0.089 11.8 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 GAO82541.1 - 0.00051 20.5 0.1 1.7 9.1 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 GAO82541.1 - 0.00061 19.0 0.3 0.38 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAO82541.1 - 0.0014 19.4 1.2 3.5 8.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO82541.1 - 0.0059 16.9 2.8 2.6 8.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 GAO82541.1 - 0.0069 15.8 0.1 2.3 7.6 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 GAO82541.1 - 0.011 15.2 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMPL PF03176.10 GAO82541.1 - 0.016 13.9 2.5 0.038 12.7 1.8 1.6 1 0 0 1 1 1 0 MMPL family DUF87 PF01935.12 GAO82541.1 - 0.034 13.9 5.1 0.097 12.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 GAO82541.1 - 0.039 13.6 0.2 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAO82541.1 - 0.045 13.9 2.0 4.8 7.3 0.1 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 GAO82541.1 - 0.11 12.3 0.3 10 5.9 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 GAO82541.1 - 0.18 11.4 2.3 2.6 7.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 GAO82541.1 - 0.23 11.1 0.9 18 4.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 GAO82541.1 - 0.71 9.2 2.7 1.5 8.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 GAO82541.1 - 3.6 6.4 4.3 21 3.9 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UQ_con PF00179.21 GAO82542.1 - 3.9e-37 126.7 0.0 5e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO82542.1 - 0.048 13.4 0.0 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Paxillin PF03535.8 GAO82542.1 - 0.091 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Paxillin family Peptidase_S8 PF00082.17 GAO82543.1 - 1.4e-54 185.2 8.5 2e-54 184.6 5.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAO82543.1 - 5.1e-18 65.4 1.1 9e-18 64.6 0.4 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Beach PF02138.13 GAO82544.1 - 7.9e-110 366.5 0.0 1.8e-109 365.3 0.0 1.7 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 GAO82544.1 - 1.7e-12 47.0 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 GAO82544.1 - 6.7e-09 36.1 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 GAO82544.1 - 4.7e-05 23.1 0.7 0.0037 17.0 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Transaldolase PF00923.14 GAO82545.1 - 1.9e-96 322.5 0.2 2.2e-96 322.3 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Sod_Cu PF00080.15 GAO82546.1 - 1.1e-45 155.3 4.2 1.3e-45 155.0 2.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 GAO82547.1 - 1.2e-77 257.1 0.2 5.1e-25 87.8 0.0 5.6 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 GAO82547.1 - 1.1e-24 86.5 0.0 2.9e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 GAO82547.1 - 0.00013 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF442 PF04273.8 GAO82547.1 - 0.15 11.9 0.7 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Putative phosphatase (DUF442) CRAL_TRIO PF00650.15 GAO82548.1 - 2.5e-25 88.8 0.0 3.7e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO82548.1 - 1.6e-11 44.1 0.0 3.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1620 PF07774.8 GAO82549.1 - 6.1e-78 261.0 0.0 1.1e-77 260.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 GAO82549.1 - 1.2e-19 70.7 19.6 1e-17 64.4 1.0 3.7 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 GAO82549.1 - 2.8e-07 29.7 4.5 0.21 11.1 0.0 6.1 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.1 GAO82549.1 - 0.02 15.1 0.2 1.1 9.6 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain DUF1479 PF07350.7 GAO82550.1 - 1.3e-169 564.0 0.0 1.6e-169 563.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Aa_trans PF01490.13 GAO82551.1 - 6e-96 321.4 10.1 1e-95 320.6 7.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.20 GAO82551.1 - 1.6e-12 47.6 0.0 7.1e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO82551.1 - 2.6e-05 24.1 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Trp_Tyr_perm PF03222.8 GAO82551.1 - 9.3e-05 21.4 14.8 9.3e-05 21.4 10.3 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family KR PF08659.5 GAO82551.1 - 0.031 13.9 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 KR domain Bax1-I PF01027.15 GAO82552.1 - 2.2e-47 161.3 32.0 2.5e-47 161.1 22.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2721 PF11026.3 GAO82552.1 - 0.015 14.9 0.2 0.015 14.9 0.2 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) 7TMR-DISM_7TM PF07695.6 GAO82552.1 - 0.8 9.3 33.1 6.9 6.2 8.8 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Orbi_NS3 PF01616.11 GAO82552.1 - 0.95 8.3 2.7 2.8 6.8 0.3 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DUF4131 PF13567.1 GAO82552.1 - 6.1 6.2 22.0 22 4.3 5.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Abhydrolase_2 PF02230.11 GAO82553.1 - 2.6e-14 53.1 0.0 2.3e-13 50.1 0.0 1.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAO82553.1 - 1.5e-08 34.7 3.5 7.7e-07 29.2 1.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO82553.1 - 3.6e-08 33.2 0.1 5.2e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO82553.1 - 0.06 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 GAO82553.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2215 PF10225.4 GAO82554.1 - 0.014 14.8 0.1 0.014 14.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Phage_connect_1 PF05135.8 GAO82554.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Metallophos PF00149.23 GAO82555.1 - 1.9e-41 141.6 0.4 2.8e-41 141.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Voldacs PF03517.8 GAO82557.1 - 4e-31 107.6 0.0 8.7e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1049 PF06305.6 GAO82558.1 - 0.11 12.0 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) PepSY_TM_2 PF13703.1 GAO82558.1 - 0.24 11.6 0.4 0.51 10.5 0.3 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix adh_short_C2 PF13561.1 GAO82559.1 - 1.9e-28 99.8 0.2 2.5e-28 99.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82559.1 - 3.5e-24 85.5 1.6 5.9e-24 84.8 1.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82559.1 - 8.4e-10 38.6 3.9 1.4e-08 34.6 2.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO82559.1 - 0.00047 19.6 0.6 0.0038 16.6 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAO82559.1 - 0.0041 16.2 0.3 0.012 14.8 0.1 1.8 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAO82559.1 - 0.0083 16.5 0.6 0.021 15.2 0.5 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAO82559.1 - 0.019 14.4 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 GAO82559.1 - 0.047 13.6 0.3 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox_2 PF07992.9 GAO82559.1 - 0.11 12.4 0.4 0.15 11.9 0.3 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HMG_CoA_synt_C PF08540.5 GAO82559.1 - 0.14 11.6 0.1 0.45 9.9 0.1 1.7 1 1 1 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal 3HCDH_N PF02737.13 GAO82559.1 - 0.14 11.7 0.5 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3301 PF11743.3 GAO82559.1 - 0.28 10.7 1.5 15 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Opi1 PF08618.5 GAO82561.1 - 2.8e-93 313.1 11.2 2.5e-54 184.8 2.5 4.0 2 1 2 4 4 4 3 Transcription factor Opi1 Perilipin PF03036.11 GAO82561.1 - 0.0094 14.8 0.2 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Perilipin family RdRP PF05183.7 GAO82562.1 - 1.8e-131 439.7 0.0 2.5e-131 439.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Root_cap PF06830.6 GAO82562.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Root cap AA_permease PF00324.16 GAO82563.1 - 1.3e-60 205.1 24.4 1.7e-60 204.7 16.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO82563.1 - 5.9e-12 44.8 22.2 5.9e-12 44.8 15.4 1.9 1 1 1 2 2 2 2 Amino acid permease NmrA PF05368.8 GAO82564.1 - 7.2e-32 110.4 0.0 9.1e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO82564.1 - 3.2e-14 53.3 0.0 5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAO82564.1 - 0.00012 22.4 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAO82564.1 - 0.00024 20.1 0.1 0.00035 19.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO82564.1 - 0.0035 17.4 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 GAO82564.1 - 0.027 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO82564.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 GAO82564.1 - 0.078 12.8 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 GAO82564.1 - 0.14 11.8 0.1 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 KR domain TMEM95 PF15203.1 GAO82565.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM95 family ABC2_membrane PF01061.19 GAO82566.1 - 2.3e-89 298.1 53.6 8.1e-45 152.5 11.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAO82566.1 - 6e-36 123.7 0.0 1.7e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO82566.1 - 3e-27 94.2 0.2 1.6e-23 82.3 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAO82566.1 - 1.2e-16 60.7 33.6 5.9e-11 41.9 11.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAO82566.1 - 1.8e-08 34.3 0.0 5.3e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO82566.1 - 1.4e-06 27.8 0.1 0.0026 17.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 GAO82566.1 - 4.2e-06 26.9 0.3 0.072 13.0 0.0 3.2 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAO82566.1 - 5e-05 22.7 0.2 0.0035 16.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO82566.1 - 5.3e-05 23.2 0.7 0.014 15.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 GAO82566.1 - 0.00013 21.4 1.3 0.02 14.3 0.5 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO82566.1 - 0.00016 21.5 0.0 0.28 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 GAO82566.1 - 0.00029 21.6 0.0 0.18 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO82566.1 - 0.00031 20.8 0.1 0.3 11.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAO82566.1 - 0.00074 18.7 0.0 0.0064 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 GAO82566.1 - 0.0014 18.2 2.3 1 9.0 0.1 2.8 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 GAO82566.1 - 0.0025 18.1 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO82566.1 - 0.0056 16.4 1.1 2.1 8.1 0.3 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 GAO82566.1 - 0.0063 16.4 0.5 0.049 13.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO82566.1 - 0.013 14.9 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 GAO82566.1 - 0.015 14.9 0.4 5.3 6.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 GAO82566.1 - 0.024 13.8 0.0 1.7 7.8 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 GAO82566.1 - 0.025 14.0 0.7 2 7.8 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 GAO82566.1 - 0.028 13.8 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 GAO82566.1 - 0.048 13.3 0.1 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 GAO82566.1 - 0.17 12.3 0.0 14 6.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 GAO82566.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAO82566.1 - 0.76 9.3 3.2 6.6 6.2 0.2 2.8 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 GAO82567.1 - 1.7e-34 119.1 22.3 1.7e-34 119.1 15.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 GAO82568.1 - 2.3e-49 167.2 0.6 2.3e-23 82.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAO82568.1 - 3.6e-23 82.1 45.4 1.8e-15 56.8 14.2 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 GAO82568.1 - 2.6e-18 66.9 2.2 0.00064 19.7 0.7 4.3 3 1 1 4 4 4 4 AAA domain Ribosomal_L19 PF01245.15 GAO82568.1 - 7.1e-18 64.4 0.4 1.8e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 AAA_29 PF13555.1 GAO82568.1 - 4.2e-10 38.9 1.8 6.7e-06 25.5 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAO82568.1 - 1.1e-09 38.9 0.5 0.00045 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAO82568.1 - 6e-09 35.4 0.0 0.057 12.6 0.1 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 GAO82568.1 - 9.5e-05 21.6 0.2 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAO82568.1 - 0.00086 18.4 0.1 0.53 9.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.1 GAO82568.1 - 0.0018 17.4 0.0 0.75 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 GAO82568.1 - 0.0018 17.9 2.6 1.1 9.0 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 GAO82568.1 - 0.0026 17.7 0.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 GAO82568.1 - 0.0091 15.4 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAO82568.1 - 0.011 15.6 0.6 2.8 7.8 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO82568.1 - 0.02 14.7 0.1 5.4 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.16 GAO82568.1 - 0.022 14.1 0.1 0.78 9.0 0.0 2.8 3 0 0 3 3 3 0 MutS domain V AAA_22 PF13401.1 GAO82568.1 - 0.029 14.4 0.4 8.2 6.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAO82568.1 - 0.031 13.7 4.4 0.36 10.2 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 GAO82568.1 - 0.04 13.3 0.2 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 GAO82568.1 - 0.04 13.5 0.5 8.3 6.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAO82568.1 - 0.057 12.9 2.3 8.9 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 GAO82568.1 - 0.095 13.2 0.1 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 GAO82568.1 - 0.17 11.2 0.2 18 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_13 PF13166.1 GAO82568.1 - 0.61 8.4 0.4 9.9 4.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.23 GAO82570.1 - 3.1e-12 45.6 0.1 1.3e-11 43.5 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Hid1 PF12722.2 GAO82571.1 - 5.1e-281 934.4 0.0 7.9e-281 933.8 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAO82571.1 - 7.6e-83 278.8 0.0 1.2e-82 278.1 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 GAO82571.1 - 2e-37 128.2 0.0 6.4e-37 126.6 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore complex component GHL1-3 PF11308.3 GAO82571.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 KAT11 PF08214.6 GAO82573.1 - 7.2e-111 370.6 0.0 1.3e-110 369.8 0.0 1.3 2 0 0 2 2 2 1 Histone acetylation protein Glyco_transf_21 PF13506.1 GAO82574.1 - 2.9e-13 49.4 0.1 2.3e-06 27.0 0.0 3.9 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 GAO82574.1 - 1e-09 38.5 0.0 3.1e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAO82574.1 - 0.002 17.8 0.0 0.0093 15.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.2 GAO82575.1 - 3e-14 53.1 1.0 7.6e-14 51.8 0.7 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82575.1 - 6.3e-13 47.8 0.4 1.3e-10 40.5 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAO82575.1 - 1.4e-12 47.8 4.2 8.4e-07 29.3 0.6 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO82575.1 - 2.6e-12 46.5 3.2 1e-08 35.1 0.5 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82575.1 - 4.3e-11 41.9 1.0 1.1e-07 31.3 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.21 GAO82576.1 - 1.9e-08 33.9 3.2 4.3e-08 32.8 2.2 1.6 1 0 0 1 1 1 1 WW domain Pneumo_att_G PF05539.6 GAO82576.1 - 4.9 6.4 7.4 7.4 5.8 5.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hydrophobin PF01185.13 GAO82577.1 - 4.3e-15 55.9 6.5 6.1e-15 55.4 4.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin VacA2 PF03077.9 GAO82577.1 - 0.078 12.5 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative vacuolating cytotoxin NMO PF03060.10 GAO82579.1 - 1.6e-63 214.8 0.5 2.8e-63 214.0 0.3 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAO82579.1 - 5.4e-11 41.9 0.0 0.00022 20.2 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAO82579.1 - 5e-05 22.3 0.2 0.0001 21.2 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAO82579.1 - 0.0044 15.9 0.4 0.012 14.5 0.3 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAO82579.1 - 0.024 13.9 0.1 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 GAO82579.1 - 0.091 11.7 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 GAO82579.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI tRNA-synt_1e PF01406.14 GAO82580.1 - 3.5e-115 384.2 0.0 5.9e-115 383.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAO82580.1 - 1.2e-05 24.2 0.4 0.13 10.8 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) GCD14 PF08704.5 GAO82581.1 - 4.8e-62 209.6 0.1 2.5e-61 207.3 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 GAO82581.1 - 0.00041 20.3 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO82581.1 - 0.03 14.9 0.1 0.091 13.3 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain TPR_11 PF13414.1 GAO82582.1 - 1.6e-09 37.2 0.8 1.9e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 GAO82582.1 - 2.8e-07 31.0 0.2 0.014 16.0 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAO82582.1 - 6e-07 28.8 3.7 0.075 12.9 1.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 GAO82582.1 - 5.7e-05 22.8 1.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.23 GAO82582.1 - 5.7e-05 22.5 1.6 0.39 10.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO82582.1 - 0.0061 16.4 1.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 GAO82582.1 - 0.0096 15.6 0.0 0.036 13.7 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 GAO82582.1 - 0.33 11.6 5.7 1.1 10.0 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1688 PF07958.6 GAO82583.1 - 1.3e-181 603.7 0.0 1.5e-181 603.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 GAO82584.1 - 5.5e-95 316.9 0.2 6.7e-95 316.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 GAO82584.1 - 1.1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAO82584.1 - 3.2e-08 33.1 0.0 5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 GAO82584.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO82584.1 - 2.4e-05 24.8 0.0 5.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAO82584.1 - 0.00015 21.3 0.0 0.00036 20.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 GAO82584.1 - 0.0032 16.9 0.1 0.0086 15.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 GAO82584.1 - 0.0081 15.1 0.1 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAO82584.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 GAO82584.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 GAO82584.1 - 0.08 12.0 0.2 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 AIG1 family G-alpha PF00503.15 GAO82584.1 - 0.15 10.7 2.9 1.9 7.1 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Adap_comp_sub PF00928.16 GAO82585.1 - 6.6e-90 300.7 0.0 8.8e-90 300.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAO82585.1 - 4.2e-06 26.5 2.6 1.7e-05 24.5 1.9 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain muHD PF10291.4 GAO82585.1 - 0.099 11.8 0.0 0.58 9.3 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 GAO82586.1 - 1.2e-28 99.6 0.0 2.2e-28 98.7 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAO82586.1 - 4.5e-08 33.5 0.0 9.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 GAO82587.1 - 3.3e-25 88.2 3.7 3.3e-25 88.2 2.5 1.4 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Transaldolase PF00923.14 GAO82588.1 - 2.3e-51 174.6 0.0 3e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Peptidase_C50 PF03568.12 GAO82590.1 - 3e-128 427.7 0.0 6.2e-128 426.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 GAO82590.1 - 0.0027 17.6 24.7 0.1 12.5 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO82590.1 - 5.7 7.1 16.4 5 7.2 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Esterase PF00756.15 GAO82591.1 - 4.7e-55 186.7 0.1 5.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAO82591.1 - 3.9e-07 29.9 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAO82591.1 - 4.7e-06 26.0 0.0 4.4e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAO82591.1 - 4.9e-05 22.6 0.2 8.5e-05 21.8 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAO82591.1 - 9.3e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO82591.1 - 0.0037 16.1 0.0 0.0074 15.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 GAO82591.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 GAO82591.1 - 0.0096 15.5 0.0 0.056 13.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 GAO82591.1 - 0.011 15.3 0.0 0.23 10.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 GAO82591.1 - 0.023 13.2 0.0 0.033 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 GAO82591.1 - 0.045 13.1 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 GAO82591.1 - 0.052 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Xpo1 PF08389.7 GAO82592.1 - 2.3e-42 144.3 2.1 1.1e-41 142.2 0.0 3.3 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 GAO82592.1 - 4.3e-05 23.2 1.2 0.099 12.7 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Nop14 PF04147.7 GAO82592.1 - 0.045 11.6 0.1 0.082 10.8 0.0 1.4 1 0 0 1 1 1 0 Nop14-like family DUF826 PF05696.6 GAO82592.1 - 0.15 12.2 0.5 39 4.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF826) FGGY_C PF02782.11 GAO82593.1 - 1.7e-35 122.4 0.0 2.6e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAO82593.1 - 9.4e-22 77.5 0.0 2.1e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 GAO82594.1 - 1.1e-61 208.4 0.5 1.4e-61 208.0 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 GAO82594.1 - 0.007 14.9 0.3 0.01 14.4 0.2 1.2 1 0 0 1 1 1 1 Cation transport protein Abhydrolase_3 PF07859.8 GAO82596.1 - 1.4e-24 86.8 0.3 1.8e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO82596.1 - 2.5e-17 62.6 0.0 3.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAO82596.1 - 3.3e-07 30.1 0.1 4.6e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO82596.1 - 0.00015 21.7 4.7 0.00015 21.7 3.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO82596.1 - 0.0012 18.1 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family HAD_2 PF13419.1 GAO82596.1 - 0.072 13.2 0.1 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Inhibitor_I9 PF05922.11 GAO82597.1 - 0.00011 22.6 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beta-lactamase PF00144.19 GAO82598.1 - 7.3e-64 215.8 0.2 8.3e-64 215.6 0.2 1.0 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 GAO82599.1 - 9.8e-40 136.3 44.5 9.8e-40 136.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82599.1 - 3.3e-09 35.8 13.9 3.3e-09 35.8 9.7 1.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 GAO82599.1 - 4.9 5.0 12.7 0.99 7.3 0.1 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.20 GAO82600.1 - 4.3e-20 72.3 0.1 6.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82600.1 - 3.1e-16 59.5 0.1 4.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Tmemb_14 PF03647.8 GAO82600.1 - 0.058 13.7 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane proteins 14C Fungal_trans_2 PF11951.3 GAO82601.1 - 3.3e-05 22.6 0.6 0.0039 15.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Xan_ur_permease PF00860.15 GAO82602.1 - 4.7e-24 84.6 28.4 3.7e-22 78.3 19.2 2.7 2 1 0 2 2 2 1 Permease family BK_channel_a PF03493.13 GAO82602.1 - 0.03 14.2 0.2 0.36 10.8 0.1 2.4 3 0 0 3 3 3 0 Calcium-activated BK potassium channel alpha subunit Zn_clus PF00172.13 GAO82603.1 - 1.1e-09 38.0 11.4 2e-09 37.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO82603.1 - 2e-05 23.6 0.1 2e-05 23.6 0.1 2.7 3 1 0 3 3 3 2 Fungal specific transcription factor domain CorA PF01544.13 GAO82604.1 - 2.6e-14 52.9 2.3 2.8e-12 46.2 1.8 2.1 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TFR_dimer PF04253.10 GAO82604.1 - 0.017 14.7 0.0 0.051 13.1 0.0 1.8 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain FadA PF09403.5 GAO82604.1 - 0.065 13.2 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Amino_oxidase PF01593.19 GAO82605.1 - 2.7e-68 231.1 0.3 6.6e-68 229.8 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO82605.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MmgE_PrpD PF03972.9 GAO82607.1 - 1.3e-101 340.0 0.4 1.7e-101 339.6 0.3 1.1 1 0 0 1 1 1 1 MmgE/PrpD family AIG2 PF06094.7 GAO82607.1 - 1.8e-10 41.1 0.1 4.6e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 AIG2-like family WSC PF01822.14 GAO82608.1 - 2e-34 117.3 32.5 4.8e-19 68.0 8.7 3.0 3 1 0 3 3 3 2 WSC domain Chitin_bind_1 PF00187.14 GAO82608.1 - 2.7e-06 27.2 22.5 2.7e-06 27.2 15.6 5.2 5 2 1 6 6 6 1 Chitin recognition protein DUF2817 PF10994.3 GAO82608.1 - 0.0013 17.9 0.4 0.58 9.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2817) BIR PF00653.16 GAO82608.1 - 4.3 7.8 7.4 0.95 9.9 0.6 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Glyco_hydro_16 PF00722.16 GAO82609.1 - 3.1e-18 65.7 0.4 1e-17 64.0 0.2 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 GAO82610.1 - 6.9e-45 153.1 2.4 6.9e-45 153.1 1.7 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO82610.1 - 2.8e-05 24.0 0.1 0.0049 16.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Fungal_trans_2 PF11951.3 GAO82611.1 - 8.7e-10 37.7 0.2 1.6e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO82611.1 - 0.0002 21.1 2.2 0.00043 20.1 1.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Radical_SAM PF04055.16 GAO82611.1 - 0.0093 16.1 0.0 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily RTA1 PF04479.8 GAO82612.1 - 1.7e-37 129.1 2.6 2.3e-37 128.6 1.8 1.2 1 0 0 1 1 1 1 RTA1 like protein NAGidase PF07555.8 GAO82612.1 - 0.18 10.6 0.2 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF2207 PF09972.4 GAO82612.1 - 0.29 9.6 3.3 0.46 9.0 2.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Nitroreductase PF00881.19 GAO82613.1 - 1.1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Peptidase_M20 PF01546.23 GAO82614.1 - 2.7e-25 88.9 2.5 6.5e-25 87.7 1.7 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO82614.1 - 3.6e-18 65.3 0.1 6.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO82614.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TIR_2 PF13676.1 GAO82614.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 TIR domain DUF3632 PF12311.3 GAO82615.1 - 1.3e-50 171.7 0.7 1.9e-50 171.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MFS_1 PF07690.11 GAO82616.1 - 6.2e-42 143.5 58.0 1.3e-41 142.4 38.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2236 PF09995.4 GAO82617.1 - 1.4e-12 47.4 0.1 4.8e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Macoilin PF09726.4 GAO82618.1 - 0.3 9.3 1.3 0.37 9.0 0.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Strep_67kDa_ant PF06100.6 GAO82619.1 - 6.3e-101 338.1 0.0 7.3e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 GAO82619.1 - 0.0006 19.7 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO82619.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 GAO82619.1 - 0.066 12.1 0.0 0.62 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO82619.1 - 0.19 10.5 0.2 3.3 6.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Acyl-CoA_dh_1 PF00441.19 GAO82620.1 - 3.3e-17 62.9 0.1 8.4e-17 61.6 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO82620.1 - 1.2e-05 24.7 0.8 7.9e-05 22.0 0.4 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO82620.1 - 0.00044 20.5 0.3 0.0032 17.7 0.2 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 GAO82621.1 - 1.7e-16 59.8 0.0 3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO82621.1 - 2.8e-08 33.5 13.1 4.6e-08 32.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.4 GAO82622.1 - 1.8e-25 89.1 0.4 1.8e-25 89.1 0.3 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 GAO82622.1 - 8.1 4.5 14.7 10 4.2 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_TAF50 PF03326.8 GAO82622.1 - 8.6 5.1 17.1 11 4.8 11.8 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) HATPase_c PF02518.21 GAO82623.1 - 3.6e-26 91.0 0.0 8e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO82623.1 - 3e-25 88.4 0.4 7.4e-25 87.1 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAO82623.1 - 6.8e-10 38.8 0.1 2e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 GAO82623.1 - 2.5e-05 24.2 0.1 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold DRY_EERY PF09750.4 GAO82623.1 - 0.055 13.5 0.3 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Alternative splicing regulator Fungal_trans PF04082.13 GAO82624.1 - 8.9e-28 96.8 1.0 1.3e-27 96.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 GAO82625.1 - 2.5e-71 240.6 0.0 2.9e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 GAO82626.1 - 4.8e-31 107.5 0.0 8.1e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAO82626.1 - 1.7e-26 92.2 0.0 5.6e-26 90.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 GAO82626.1 - 3.7e-25 87.5 0.4 6.4e-25 86.7 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 GAO82626.1 - 1.3e-05 25.1 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAO82626.1 - 0.026 14.4 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.13 GAO82627.1 - 1.7e-31 109.2 0.0 2.5e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAO82627.1 - 8e-09 35.7 0.0 2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 GAO82627.1 - 2.4e-07 30.6 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 GAO82627.1 - 9.4e-07 28.8 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.12 GAO82627.1 - 0.00051 20.3 3.7 2 8.7 0.0 4.8 5 0 0 5 5 5 1 Low-density lipoprotein receptor repeat class B 2-Hacid_dh_C PF02826.14 GAO82627.1 - 0.0069 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAO82627.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 GAO82627.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 GAO82628.1 - 7e-06 25.6 2.1 1.8e-05 24.3 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO82628.1 - 0.043 13.4 5.4 0.23 11.1 3.7 2.3 1 1 0 1 1 1 0 F-box domain AMP-binding PF00501.23 GAO82629.1 - 4e-82 275.8 0.0 6e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO82629.1 - 3.3e-63 212.9 0.0 3e-62 209.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAO82629.1 - 5.1e-38 130.6 9.5 4.9e-36 124.1 2.1 3.8 4 0 0 4 4 4 2 short chain dehydrogenase KR PF08659.5 GAO82629.1 - 3.3e-21 75.7 4.0 6.1e-18 65.1 1.7 2.7 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 GAO82629.1 - 1.1e-17 64.6 0.1 3.2e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO82629.1 - 2.1e-16 60.1 0.0 6.5e-10 38.8 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO82629.1 - 2e-11 43.9 0.0 6.1e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 GAO82629.1 - 2.1e-08 34.3 0.6 8.9e-05 22.5 0.4 3.7 2 1 1 3 3 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO82629.1 - 2.5e-07 29.6 0.0 0.0075 14.9 0.0 3.1 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO82629.1 - 4.2e-07 29.1 0.1 0.00022 20.2 0.0 3.0 3 0 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.1 GAO82629.1 - 8.9e-07 29.7 0.7 1.3e-05 26.0 0.1 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DFP PF04127.10 GAO82629.1 - 0.0004 20.0 0.6 0.0072 15.9 0.4 2.5 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 GAO82629.1 - 0.0019 17.1 0.5 0.45 9.3 0.0 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAO82629.1 - 0.025 13.8 1.2 0.36 10.0 0.6 2.9 5 0 0 5 5 5 0 NmrA-like family THF_DHG_CYH_C PF02882.14 GAO82629.1 - 0.04 13.0 0.1 0.15 11.0 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 GAO82629.1 - 0.12 12.2 0.9 0.3 10.8 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Wax2_C PF12076.3 GAO82629.1 - 0.31 10.7 0.0 0.56 9.9 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain bZIP_1 PF00170.16 GAO82630.1 - 8e-05 22.5 24.1 0.00084 19.2 16.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor MMR1 PF08505.5 GAO82630.1 - 0.00037 20.5 1.2 0.00043 20.3 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein DUF1501 PF07394.7 GAO82630.1 - 0.11 11.3 2.1 0.15 10.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) bZIP_2 PF07716.10 GAO82630.1 - 0.15 11.8 29.6 0.19 11.5 16.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 GAO82630.1 - 0.18 11.7 10.8 0.25 11.3 7.5 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 GAO82630.1 - 0.54 9.8 8.7 0.75 9.3 6.0 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 GAO82630.1 - 1.2 7.9 10.7 1.8 7.4 7.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NmrA PF05368.8 GAO82632.1 - 4.2e-33 114.5 0.0 5.2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO82632.1 - 8.1e-15 55.2 0.1 1.3e-14 54.6 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO82632.1 - 1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO82632.1 - 3e-05 24.0 0.0 6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82632.1 - 0.00012 21.7 0.4 0.00021 20.9 0.0 1.6 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 GAO82632.1 - 0.00056 18.6 0.0 0.001 17.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO82632.1 - 0.0025 16.7 0.0 0.01 14.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO82632.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAO82632.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO82632.1 - 0.027 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus BRK PF07533.11 GAO82632.1 - 0.11 11.9 0.1 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 BRK domain Pec_lyase_C PF00544.14 GAO82633.1 - 2.3e-18 66.4 9.6 6.2e-18 64.9 6.6 1.7 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 GAO82633.1 - 4.6e-05 23.2 12.8 0.00094 18.9 8.8 2.2 1 1 0 1 1 1 1 Right handed beta helix region FAD_binding_3 PF01494.14 GAO82634.1 - 6.2e-12 45.2 0.1 4.3e-11 42.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO82634.1 - 8.9e-05 21.5 0.1 0.00016 20.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 GAO82636.1 - 1.9e-07 30.2 0.5 2.9e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.11 GAO82637.1 - 1.2e-09 38.0 14.1 1.7e-09 37.6 8.1 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAO82637.1 - 1.1e-07 31.4 5.3 1.1e-07 31.4 3.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) DUF347 PF03988.7 GAO82637.1 - 0.53 10.2 4.3 13 5.7 0.2 3.4 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Ferric_reduct PF01794.14 GAO82637.1 - 6.8 6.7 14.1 0.39 10.8 3.3 2.9 1 1 2 3 3 3 0 Ferric reductase like transmembrane component ADH_zinc_N PF00107.21 GAO82640.1 - 3e-09 36.4 0.0 4.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO82640.1 - 2.1e-05 24.1 0.0 4.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO82640.1 - 0.039 14.8 0.0 0.076 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Amnionless PF14828.1 GAO82641.1 - 0.0083 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless VSP PF03302.8 GAO82641.1 - 0.011 14.4 0.6 0.017 13.7 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM154 PF15102.1 GAO82641.1 - 0.04 13.6 0.8 0.18 11.5 0.3 2.0 2 0 0 2 2 2 0 TMEM154 protein family Plasmodium_Vir PF05795.6 GAO82641.1 - 0.041 13.0 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF908 PF06012.7 GAO82641.1 - 0.1 11.8 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF912 PF06024.7 GAO82641.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sporozoite_P67 PF05642.6 GAO82641.1 - 0.65 7.7 8.8 0.81 7.4 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSA-2c PF12238.3 GAO82641.1 - 1.1 8.8 7.6 2.1 7.9 5.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med3 PF11593.3 GAO82641.1 - 2.4 7.3 11.2 3.1 6.9 7.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 GAO82641.1 - 3.3 5.5 17.4 4.6 5.1 12.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-LITAF-like PF10601.4 GAO82642.1 - 2.8e-07 30.3 0.2 3.8e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 GAO82642.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc ribbon domain DUF605 PF04652.11 GAO82642.1 - 3.8 6.8 6.6 3.5 6.9 4.6 1.1 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 GAO82643.1 - 9.2e-184 596.4 58.6 9.1e-24 83.6 1.3 10.0 2 2 11 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAO82643.1 - 1.1e-127 409.9 30.6 1.1e-09 37.5 0.0 20.0 19 1 1 20 20 20 17 Ankyrin repeat Ank_4 PF13637.1 GAO82643.1 - 1.1e-89 293.4 19.4 9.4e-12 45.1 0.0 14.6 10 4 5 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82643.1 - 2e-87 278.2 23.2 7.8e-06 25.6 0.0 20.0 19 1 1 20 20 20 17 Ankyrin repeat Ank_5 PF13857.1 GAO82643.1 - 3.3e-75 246.4 31.7 6.2e-09 35.8 0.0 16.2 5 4 13 19 19 19 16 Ankyrin repeats (many copies) HET PF06985.6 GAO82643.1 - 3.3e-07 30.5 4.7 4.4e-06 26.8 0.3 2.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mic1 PF07035.7 GAO82643.1 - 0.15 11.4 0.0 43 3.4 0.0 3.6 4 0 0 4 4 4 0 Colon cancer-associated protein Mic1-like HSP20 PF00011.16 GAO82644.1 - 4.6e-24 84.2 0.0 6.3e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family NAD_binding_2 PF03446.10 GAO82645.1 - 2.5e-40 137.9 0.0 4.1e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAO82645.1 - 1.5e-39 134.7 3.5 1.1e-28 99.7 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAO82645.1 - 0.00012 22.4 0.0 0.00047 20.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAO82645.1 - 0.00027 20.6 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO82645.1 - 0.021 14.0 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAO82645.1 - 0.088 12.1 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F_bP_aldolase PF01116.15 GAO82646.1 - 5.9e-86 288.1 0.0 6.6e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ERG4_ERG24 PF01222.12 GAO82648.1 - 9.2e-130 433.0 6.9 1.1e-129 432.7 4.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAO82648.1 - 6e-06 25.7 0.5 1.8e-05 24.1 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_hydro_71 PF03659.9 GAO82650.1 - 1.3e-147 491.3 8.7 1.7e-147 490.9 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.1 GAO82650.1 - 5.8e-14 52.6 0.2 1.2e-13 51.5 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aspzincin_M35 PF14521.1 GAO82650.1 - 1.1e-07 32.4 0.1 4.2e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF1804 PF08822.6 GAO82651.1 - 0.063 13.0 0.4 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) MBOAT_2 PF13813.1 GAO82652.1 - 9.6e-20 70.4 8.5 9.6e-20 70.4 5.9 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Methyltransf_3 PF01596.12 GAO82653.1 - 4.1e-15 55.3 0.0 5.4e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAO82653.1 - 3.7e-11 43.8 0.0 5.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 GAO82653.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 GAO82653.1 - 0.0054 17.3 0.0 0.0088 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO82653.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAD_binding_3 PF01494.14 GAO82654.1 - 3.6e-13 49.2 0.1 7.1e-13 48.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAO82655.1 - 2.7e-33 115.4 0.0 3.5e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO82655.1 - 1.7e-08 34.2 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 GAO82655.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Pectate_lyase_3 PF12708.2 GAO82656.1 - 3.5e-61 207.1 16.7 4.9e-50 170.7 4.6 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein Gelsolin PF00626.17 GAO82656.1 - 7.6e-38 128.0 0.3 2.3e-12 46.4 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat End_N_terminal PF12218.3 GAO82656.1 - 0.097 12.1 0.2 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Fer2_3 PF13085.1 GAO82657.1 - 1.7e-31 108.3 0.0 2.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 GAO82657.1 - 2.2e-09 37.5 6.2 2.2e-09 37.5 4.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAO82657.1 - 8.5e-09 35.3 4.6 8.5e-09 35.3 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAO82657.1 - 0.00051 20.4 2.2 0.00051 20.4 1.5 2.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAO82657.1 - 0.00057 20.0 4.0 0.037 14.2 0.4 3.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAO82657.1 - 0.00074 19.2 4.2 0.00074 19.2 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAO82657.1 - 0.0045 17.3 4.2 0.0045 17.3 2.9 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 GAO82657.1 - 0.0085 15.8 0.3 0.0085 15.8 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 GAO82657.1 - 1.6 9.1 4.6 2.1 8.8 0.8 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 GAO82657.1 - 5.7 7.5 7.5 1.2 9.7 0.1 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Pec_lyase_C PF00544.14 GAO82658.1 - 2.3e-20 72.9 6.9 3.7e-20 72.2 4.8 1.4 1 0 0 1 1 1 1 Pectate lyase DUF3480 PF11979.3 GAO82659.1 - 0.045 12.3 0.0 0.076 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Oxidored_molyb PF00174.14 GAO82661.1 - 2.3e-44 150.7 0.0 3.9e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAO82661.1 - 5.1e-38 129.6 0.6 1.1e-37 128.5 0.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 GAO82661.1 - 3.1e-22 79.1 0.0 1.2e-21 77.3 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAO82661.1 - 4.3e-22 78.0 0.0 1.8e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 GAO82661.1 - 2.3e-18 65.7 0.0 6.4e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 GAO82661.1 - 0.0043 16.9 0.0 0.2 11.5 0.0 2.5 1 1 0 2 2 2 1 Ferric reductase NAD binding domain MFS_1 PF07690.11 GAO82662.1 - 2e-23 82.7 38.9 2e-23 82.7 27.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82662.1 - 1.5e-09 36.9 11.2 1.5e-09 36.9 7.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO82662.1 - 2.6e-08 32.5 17.3 4.8e-08 31.6 12.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2422 PF10337.4 GAO82663.1 - 4.5e-132 441.1 0.6 4.5e-132 441.1 0.4 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAO82663.1 - 1.3e-16 60.6 14.5 1.3e-16 60.6 10.1 2.8 3 0 0 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAO82663.1 - 6e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 GAO82663.1 - 0.0048 16.7 6.1 0.0048 16.7 4.2 3.4 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF939) Tad PF13400.1 GAO82663.1 - 0.05 13.6 1.9 0.33 11.0 1.3 2.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like ALMT PF11744.3 GAO82663.1 - 0.39 9.3 8.6 0.76 8.3 0.0 3.3 2 2 1 3 3 3 0 Aluminium activated malate transporter DPBB_1 PF03330.13 GAO82664.1 - 2.7e-09 36.9 0.0 6.2e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MASE1 PF05231.9 GAO82664.1 - 0.056 12.4 0.1 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 MASE1 Barwin PF00967.12 GAO82664.1 - 0.1 12.2 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Barwin family ThiF PF00899.16 GAO82665.1 - 2.5e-42 143.9 0.0 4.4e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAO82665.1 - 8.4e-27 92.5 0.1 1.6e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 GAO82665.1 - 1.9e-10 41.0 0.0 4.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 GAO82665.1 - 0.0068 16.5 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAO82665.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 GAO82665.1 - 0.026 13.4 2.1 0.033 13.1 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO82665.1 - 0.027 13.5 0.4 0.32 9.9 0.9 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 GAO82665.1 - 0.029 14.5 0.0 0.09 13.0 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding TMF_DNA_bd PF12329.3 GAO82665.1 - 0.059 13.1 1.4 0.12 12.2 1.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 GAO82665.1 - 0.17 11.8 1.8 0.28 11.1 1.2 1.4 1 0 0 1 1 1 0 FlxA-like protein Amidase PF01425.16 GAO82666.1 - 4.1e-69 233.5 0.0 3.1e-67 227.3 0.0 2.1 1 1 0 1 1 1 1 Amidase Glyco_hydro_43 PF04616.9 GAO82667.1 - 1.6e-38 132.4 1.7 1.6e-38 132.4 1.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 NmrA PF05368.8 GAO82668.1 - 1.2e-24 86.8 0.1 1.6e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO82668.1 - 9e-17 61.6 0.4 1.4e-16 61.0 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO82668.1 - 6.3e-07 29.0 0.3 1.1e-06 28.2 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAO82668.1 - 0.0047 15.9 1.6 0.0056 15.7 0.4 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAO82668.1 - 0.0063 16.8 0.3 0.015 15.5 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Lact_bio_phlase PF09508.5 GAO82668.1 - 0.04 11.5 0.0 0.055 11.1 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase RmlD_sub_bind PF04321.12 GAO82668.1 - 0.048 12.5 0.2 0.85 8.4 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 GAO82668.1 - 0.058 13.3 0.2 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAO82668.1 - 0.099 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 GAO82668.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 GAO82668.1 - 0.65 9.0 3.4 4.1 6.4 1.8 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ABC_tran PF00005.22 GAO82669.1 - 1.1e-53 181.2 0.0 8.3e-32 110.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO82669.1 - 2.2e-26 92.8 14.5 4.3e-19 68.9 5.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO82669.1 - 2.8e-10 39.7 0.1 0.0011 18.1 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO82669.1 - 8.2e-07 29.2 0.3 0.14 12.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 GAO82669.1 - 1.5e-06 27.7 0.1 0.021 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO82669.1 - 8.4e-06 25.2 0.1 0.039 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAO82669.1 - 9.3e-06 24.9 0.0 0.045 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAO82669.1 - 1.8e-05 25.1 0.0 0.0085 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO82669.1 - 2e-05 24.6 0.5 0.29 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAO82669.1 - 5.6e-05 23.3 0.1 0.052 13.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAO82669.1 - 7.9e-05 22.5 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAO82669.1 - 0.00013 21.5 0.0 0.27 10.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.7 GAO82669.1 - 0.00055 19.0 0.3 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 GAO82669.1 - 0.00075 20.3 0.3 0.29 11.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAO82669.1 - 0.0046 16.8 0.0 15 5.6 0.0 3.8 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAO82669.1 - 0.006 16.0 0.6 2.6 7.3 0.0 3.0 2 1 1 3 3 3 1 AAA-like domain Miro PF08477.8 GAO82669.1 - 0.0087 16.5 0.6 5.8 7.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ATP-synt_ab PF00006.20 GAO82669.1 - 0.073 12.5 0.0 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 GAO82669.1 - 0.11 11.4 0.0 6.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 GAO82669.1 - 0.12 11.9 0.0 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 GAO82669.1 - 0.13 11.6 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_18 PF13238.1 GAO82669.1 - 0.17 12.2 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAO82669.1 - 0.26 10.2 0.5 0.96 8.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 GAO82669.1 - 3.6 7.3 6.0 1.1 9.0 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 Glyco_hydro_92 PF07971.7 GAO82670.1 - 2.2e-154 514.8 1.7 2.6e-154 514.5 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ACC_epsilon PF13822.1 GAO82671.1 - 0.074 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Glyco_hydro_28 PF00295.12 GAO82672.1 - 5.8e-32 110.9 3.3 7.3e-32 110.6 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 GAO82672.1 - 5.7e-09 36.4 7.5 3.6e-08 33.8 5.3 2.3 1 1 1 2 2 2 1 Pectate lyase superfamily protein Alpha-amylase_C PF02806.13 GAO82673.1 - 7.6e-24 83.6 0.0 1.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 GAO82673.1 - 4.3e-19 69.0 0.0 7.6e-15 55.1 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 GAO82673.1 - 2.6e-18 65.8 0.2 6.8e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 GAO82673.1 - 0.085 11.2 0.1 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 ATP-synt_ab PF00006.20 GAO82674.1 - 3.5e-62 209.7 0.0 5.2e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAO82674.1 - 1.5e-25 89.8 0.4 2.8e-25 88.9 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAO82674.1 - 1.3e-23 82.9 0.8 5.1e-23 81.0 0.3 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 GAO82674.1 - 0.0016 17.6 0.2 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 GAO82674.1 - 0.0033 16.8 0.1 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAO82674.1 - 0.0095 15.6 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 GAO82674.1 - 0.018 15.2 0.1 0.61 10.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO82674.1 - 0.02 14.9 0.4 0.31 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAO82674.1 - 0.027 14.1 0.1 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 GAO82674.1 - 0.028 13.6 0.1 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 GAO82674.1 - 0.041 13.5 0.2 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 GAO82674.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 GAO82674.1 - 0.093 12.8 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO82674.1 - 0.22 10.3 1.2 0.7 8.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain COX4 PF02936.9 GAO82675.1 - 3.9e-53 179.0 0.7 5e-53 178.6 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 GAO82675.1 - 2.9 8.3 10.1 0.57 10.6 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Cofilin_ADF PF00241.15 GAO82676.1 - 1.1e-22 80.2 0.1 1.3e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.1 GAO82677.1 - 1.3e-06 27.8 0.1 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO82677.1 - 0.00095 18.5 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3948 PF13134.1 GAO82677.1 - 2 7.9 4.8 4 6.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) She9_MDM33 PF05546.6 GAO82678.1 - 1.9e-93 311.8 10.9 2.8e-93 311.2 7.5 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Pmp3 PF01679.12 GAO82678.1 - 2e-19 69.0 7.7 2e-19 69.0 5.4 1.6 2 0 0 2 2 2 1 Proteolipid membrane potential modulator PsbH PF00737.15 GAO82678.1 - 0.67 9.5 6.2 0.049 13.1 0.6 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein UCR_TM PF02921.9 GAO82679.1 - 5.3e-18 65.0 0.8 1e-17 64.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 GAO82679.1 - 2.6e-17 62.1 0.1 4.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CBFD_NFYB_HMF PF00808.18 GAO82680.1 - 5.6e-08 32.7 1.6 0.0024 17.8 0.0 2.9 3 0 0 3 3 3 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 GAO82681.1 - 8.3e-91 304.6 30.9 8.3e-91 304.6 21.4 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAO82681.1 - 1.8e-13 50.0 0.0 7.1e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain EamA PF00892.15 GAO82682.1 - 2.8e-06 27.4 6.8 2.8e-06 27.4 4.7 1.7 1 1 1 2 2 2 1 EamA-like transporter family EmrE PF13536.1 GAO82682.1 - 0.00074 19.7 9.3 0.0011 19.1 6.3 1.6 1 1 0 1 1 1 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 GAO82682.1 - 0.0025 17.6 1.2 0.0033 17.2 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 TPT PF03151.11 GAO82682.1 - 0.6 9.7 6.4 2.8 7.5 4.4 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF543 PF04418.7 GAO82682.1 - 4.8 7.2 6.5 1.2 9.1 1.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF543) tRNA-synt_1b PF00579.20 GAO82683.1 - 1.8e-54 184.8 0.0 3.5e-54 183.9 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PNPOx_C PF10590.4 GAO82684.1 - 1.6e-20 72.2 5.4 3.5e-20 71.2 2.4 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 GAO82684.1 - 6.9e-10 38.8 0.0 0.00082 19.3 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 GAO82685.1 - 1.7e-49 165.6 8.1 5.5e-10 39.0 0.0 15.1 12 5 5 17 17 17 10 PPR repeat family PPR_3 PF13812.1 GAO82685.1 - 1e-31 106.4 30.3 5.9e-05 23.0 0.0 17.1 19 0 0 19 19 19 8 Pentatricopeptide repeat domain PPR PF01535.15 GAO82685.1 - 3.2e-29 98.8 11.8 0.00043 20.0 0.0 14.5 16 1 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 GAO82685.1 - 1e-21 76.0 0.1 3e-07 29.7 0.0 10.6 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 GAO82685.1 - 1.5e-07 31.5 0.1 0.00017 21.6 0.0 4.2 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 GAO82685.1 - 0.0016 17.3 0.0 1.6 7.5 0.0 3.4 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway SelB-wing_2 PF09106.6 GAO82685.1 - 0.015 15.1 0.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 0 Elongation factor SelB, winged helix TPR_8 PF13181.1 GAO82685.1 - 0.031 14.0 0.4 13 5.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO82685.1 - 0.052 14.1 23.7 17 6.3 0.4 11.3 16 0 0 16 16 16 0 Tetratricopeptide repeat FA_hydroxylase PF04116.8 GAO82686.1 - 4e-13 49.7 13.2 4e-13 49.7 9.2 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GHMP_kinases_N PF00288.21 GAO82687.1 - 5.4e-14 51.9 1.4 1.3e-13 50.7 0.4 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAO82687.1 - 8e-11 41.9 0.0 2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Sugar_tr PF00083.19 GAO82688.1 - 4e-94 315.7 32.2 7e-69 232.5 12.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO82688.1 - 3.3e-21 75.3 32.9 2.5e-16 59.3 5.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 GAO82688.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3040 PF11239.3 GAO82688.1 - 1.5 8.9 4.0 1.1 9.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Arrestin_C PF02752.17 GAO82689.1 - 2.1e-06 27.9 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAO82689.1 - 0.00013 21.8 0.3 0.00087 19.1 0.2 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rad60-SLD_2 PF13881.1 GAO82690.1 - 1.7e-13 50.3 0.3 3.4e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAO82690.1 - 8.6e-06 25.0 0.0 2.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 GAO82690.1 - 0.0018 18.4 0.1 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 GAO82691.1 - 9.8e-21 74.0 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 GAO82692.1 - 3.5e-41 139.4 2.0 4.5e-41 139.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 GAO82693.1 - 4.8e-142 472.7 6.7 5.9e-142 472.4 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 GAO82694.1 - 6.6e-299 993.7 9.5 7.5e-299 993.6 6.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 GAO82695.1 - 5e-47 160.3 0.0 6.6e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAO82695.1 - 5.1e-27 93.6 0.2 9.2e-27 92.7 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 GAO82695.1 - 3.9e-16 58.5 0.0 5.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO82695.1 - 1.2e-12 47.3 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAO82695.1 - 3.7e-12 45.7 0.1 7.1e-11 41.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAO82695.1 - 5.7e-11 42.6 0.0 9.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO82695.1 - 2.6e-09 37.3 0.0 4.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO82695.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAO82695.1 - 1.2e-06 27.6 0.1 8.8e-06 24.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAO82695.1 - 0.0017 17.6 0.0 0.0051 16.0 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 GAO82695.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_lysozyme PF00959.14 GAO82695.1 - 0.018 15.3 0.2 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 Phage lysozyme UDPG_MGDP_dh_N PF03721.9 GAO82695.1 - 0.027 13.8 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 GAO82695.1 - 0.11 10.7 0.0 0.19 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.20 GAO82696.1 - 6.1e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO82696.1 - 1.6e-07 31.1 0.0 6.4e-07 29.2 0.0 1.9 3 0 0 3 3 3 1 KR domain adh_short_C2 PF13561.1 GAO82696.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAO82696.1 - 0.006 15.7 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Apt1 PF10351.4 GAO82696.1 - 0.025 13.4 0.4 0.033 13.0 0.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_10 PF13460.1 GAO82696.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAO82696.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G-patch PF01585.18 GAO82697.1 - 0.00026 20.6 0.4 0.00057 19.6 0.1 1.7 2 0 0 2 2 2 1 G-patch domain DUF3439 PF11921.3 GAO82697.1 - 0.43 10.3 3.5 0.69 9.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SUV3_C PF12513.3 GAO82698.1 - 3.2e-15 55.2 0.1 7.3e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 GAO82698.1 - 8.5e-09 35.1 0.0 2.8e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4614 PF15391.1 GAO82698.1 - 0.063 13.0 1.7 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TK PF00265.13 GAO82698.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase HA2 PF04408.18 GAO82699.1 - 5.6e-29 100.1 0.2 2.2e-28 98.2 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAO82699.1 - 1.4e-27 95.7 0.0 1.5e-26 92.4 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAO82699.1 - 2.1e-12 46.7 0.0 5.4e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 GAO82699.1 - 7.6e-11 41.9 0.4 1.6e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 GAO82699.1 - 4.6e-06 26.2 0.0 9.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO82699.1 - 9.5e-05 22.5 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAO82699.1 - 0.00028 19.8 0.0 0.00066 18.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAO82699.1 - 0.0025 17.5 0.2 0.0079 15.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAO82699.1 - 0.006 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO82699.1 - 0.042 13.8 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 GAO82699.1 - 0.14 12.2 0.0 0.55 10.2 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Npa1 PF11707.3 GAO82700.1 - 4.7e-110 367.6 0.1 1.3e-109 366.2 0.1 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal SNF2_N PF00176.18 GAO82703.1 - 6.9e-53 179.3 0.1 1.5e-52 178.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO82703.1 - 4.1e-07 29.7 0.0 1.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAO82703.1 - 0.00028 20.8 8.5 0.00068 19.6 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO82703.1 - 0.0011 18.5 5.4 0.0021 17.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO82703.1 - 0.0032 17.1 7.0 0.0066 16.1 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO82703.1 - 0.011 15.4 5.6 0.031 13.9 3.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCM PF00493.18 GAO82704.1 - 9.9e-132 438.7 0.2 1.6e-131 438.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAO82704.1 - 2e-18 67.0 0.2 2e-18 67.0 0.1 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO82704.1 - 1.7e-05 24.1 0.0 0.00012 21.2 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAO82704.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 GAO82704.1 - 0.0016 18.1 0.0 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAO82704.1 - 0.0043 16.6 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.1 GAO82705.1 - 0.00064 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF221 PF02714.10 GAO82706.1 - 4e-107 357.8 17.5 4e-107 357.8 12.1 3.5 4 0 0 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAO82706.1 - 6.1e-45 152.5 3.1 6.1e-45 152.5 2.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAO82706.1 - 6.5e-33 112.4 2.2 1.2e-32 111.6 0.7 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 GAO82706.1 - 9.2e-21 74.1 0.2 1.8e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ODV-E18 PF10717.4 GAO82706.1 - 0.29 10.6 7.2 7.5 6.0 0.1 3.4 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 ABC_tran PF00005.22 GAO82707.1 - 1.5e-46 158.1 0.0 4.2e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO82707.1 - 3.3e-38 131.6 30.4 3.9e-24 85.5 10.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 GAO82707.1 - 9.1e-11 42.2 0.1 0.5 10.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 GAO82707.1 - 2.8e-06 27.4 0.2 0.0064 16.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 GAO82707.1 - 9.5e-06 26.1 0.4 0.068 13.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAO82707.1 - 1e-05 24.9 0.3 0.14 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAO82707.1 - 1.1e-05 24.7 0.6 1.7 7.7 0.0 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 GAO82707.1 - 2e-05 24.4 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAO82707.1 - 0.0001 23.1 2.1 0.073 13.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAO82707.1 - 0.00012 22.4 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAO82707.1 - 0.00013 21.1 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 GAO82707.1 - 0.00031 19.9 0.3 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAO82707.1 - 0.00094 19.1 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO82707.1 - 0.0013 19.0 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO82707.1 - 0.0014 18.7 0.0 0.33 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 GAO82707.1 - 0.0038 16.8 2.0 1.4 8.4 0.1 2.7 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAO82707.1 - 0.0039 16.6 0.1 0.43 10.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 GAO82707.1 - 0.0048 15.5 0.8 0.32 9.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 GAO82707.1 - 0.0053 15.6 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 GAO82707.1 - 0.0063 15.9 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAO82707.1 - 0.0088 15.1 0.0 0.9 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 GAO82707.1 - 0.0098 15.7 2.0 0.43 10.3 0.2 2.8 3 0 0 3 3 2 1 Dynamin family MobB PF03205.9 GAO82707.1 - 0.01 15.5 1.1 0.46 10.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 GAO82707.1 - 0.022 14.2 0.7 0.17 11.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAO82707.1 - 0.023 14.5 2.4 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 GAO82707.1 - 0.025 13.9 0.2 0.61 9.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 GAO82707.1 - 0.037 12.6 0.0 4.2 5.8 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ArgK PF03308.11 GAO82707.1 - 0.046 12.4 1.2 5.7 5.6 0.0 2.4 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 GAO82707.1 - 0.064 12.9 0.7 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 GAO82707.1 - 0.093 12.1 0.3 18 4.6 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain ATP-synt_ab PF00006.20 GAO82707.1 - 0.12 11.8 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 GAO82707.1 - 0.22 11.3 0.0 30 4.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 GAO82707.1 - 0.25 10.8 0.6 3.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 GAO82707.1 - 0.26 10.9 1.0 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MFS_1 PF07690.11 GAO82708.1 - 3.4e-13 49.0 11.6 3.4e-13 49.0 8.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO82710.1 - 6.9e-08 31.6 0.1 2e-07 30.1 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Polysacc_lyase PF14099.1 GAO82711.1 - 2.3e-52 177.8 9.2 2.6e-52 177.7 6.3 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Triabin PF03973.8 GAO82711.1 - 0.015 14.9 0.3 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 Triabin Laminin_G_2 PF02210.19 GAO82711.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain DUF3405 PF11885.3 GAO82712.1 - 2.8e-184 612.9 3.4 5.8e-184 611.9 2.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Zn_clus PF00172.13 GAO82714.1 - 0.044 13.7 2.1 0.044 13.7 1.4 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxase_2 PF12766.2 GAO82715.1 - 1e-28 99.5 0.0 2e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.1 GAO82716.1 - 5e-54 182.5 2.1 8.5e-54 181.7 0.1 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 GAO82716.1 - 5.6e-10 38.6 7.3 8.7e-05 22.0 1.3 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO82716.1 - 8.5e-10 38.2 16.2 2.3e-06 27.2 3.1 3.4 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 GAO82716.1 - 0.088 12.8 5.8 37 4.8 0.1 5.0 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 GAO82716.1 - 7 7.3 6.5 2.6e+02 2.5 0.0 4.3 3 1 0 3 3 3 0 Leucine rich repeat Ammonium_transp PF00909.16 GAO82717.1 - 1.3e-105 353.1 23.6 1.8e-105 352.7 16.3 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family GDA1_CD39 PF01150.12 GAO82717.1 - 2.5e-96 322.8 0.0 3.6e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF1691 PF07950.6 GAO82717.1 - 0.22 11.4 3.3 1.8 8.4 2.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) Acyltransferase PF01553.16 GAO82718.1 - 4.2e-17 61.8 0.0 1.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.10 GAO82719.1 - 1.1e-80 270.4 0.0 2e-80 269.5 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 GAO82720.1 - 3.8e-40 137.1 0.0 5.5e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO82720.1 - 2.5e-19 68.9 0.0 5.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAO82720.1 - 2.3e-18 65.4 0.1 4.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAO82720.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 GAO82721.1 - 4.3e-21 73.9 7.7 0.00086 19.0 0.0 7.7 7 2 0 7 7 7 6 WD domain, G-beta repeat MFS_1 PF07690.11 GAO82722.1 - 1.1e-52 178.8 63.3 2e-45 155.0 29.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82722.1 - 8.2e-09 34.5 16.3 8.2e-09 34.5 11.3 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.3 GAO82722.1 - 6.4e-08 31.5 6.7 4.5e-05 22.2 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain TRI12 PF06609.8 GAO82722.1 - 2.2e-06 26.2 21.5 3.2e-06 25.6 14.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 GAO82722.1 - 0.0006 19.6 12.0 0.0006 19.6 8.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF485 PF04341.7 GAO82722.1 - 5.3 6.8 9.9 0.095 12.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 GATase PF00117.23 GAO82723.1 - 1.8e-11 43.8 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAO82723.1 - 0.032 13.6 0.1 0.52 9.7 0.1 2.5 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 GAO82723.1 - 0.064 12.8 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.7 GAO82724.1 - 1.9e-62 210.3 0.0 2.2e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GLTT PF01744.15 GAO82724.1 - 0.038 13.4 1.0 0.54 9.7 0.2 2.2 2 0 0 2 2 2 0 GLTT repeat (6 copies) NUDIX PF00293.23 GAO82725.1 - 1e-09 38.1 0.1 1.6e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 GAO82726.1 - 2.9e-36 124.6 0.0 3.2e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 GAO82727.1 - 1.1e-131 439.0 0.0 1.2e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 GAO82728.1 - 8.5e-14 51.1 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2361 PF10153.4 GAO82728.1 - 0.016 15.3 2.7 0.024 14.8 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) UPF0086 PF01868.11 GAO82729.1 - 1.3e-26 92.0 0.9 7.8e-17 60.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function UPF0086 2OG-FeII_Oxy PF03171.15 GAO82730.1 - 3.5e-14 52.8 0.0 1.1e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAO82730.1 - 3.2e-13 50.2 0.0 1.1e-12 48.5 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal SNF2_N PF00176.18 GAO82731.1 - 6.5e-55 186.0 0.0 9.6e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 GAO82731.1 - 2.7e-08 32.9 0.0 7.5e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 GAO82731.1 - 1.1e-07 31.5 0.0 3.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO82731.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.24 GAO82731.1 - 1.2 8.8 24.0 0.11 12.2 9.2 2.9 1 1 1 2 2 2 0 PHD-finger FYVE PF01363.16 GAO82732.1 - 0.0069 16.2 2.9 0.019 14.8 1.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger Cofilin_ADF PF00241.15 GAO82733.1 - 6e-11 42.3 0.0 6.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 GAO82734.1 - 1.9e-36 124.6 0.0 3.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 GAO82735.1 - 3.2e-59 198.9 0.1 3.8e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO82735.1 - 1.1e-18 67.8 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO82735.1 - 1.3e-08 34.2 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO82735.1 - 1.6e-07 30.9 0.1 7.6e-07 28.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAO82735.1 - 0.0032 16.7 0.0 0.0054 16.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 GAO82735.1 - 0.0045 16.9 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 GAO82735.1 - 0.062 12.7 0.9 1.4 8.3 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 GAO82735.1 - 0.076 11.9 0.1 1.8 7.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 GAO82735.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 GAO82735.1 - 0.3 10.6 1.7 3.2 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 GAO82736.1 - 2.6e-34 118.5 0.0 3.8e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO82736.1 - 4.3e-15 56.1 0.0 5.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO82736.1 - 3.5e-13 49.6 0.0 5.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO82736.1 - 0.0047 15.8 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAO82736.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO82736.1 - 0.08 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAO82736.1 - 0.11 12.6 0.3 0.38 10.8 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Adeno_E3_CR2 PF02439.10 GAO82737.1 - 0.49 9.9 0.1 0.49 9.9 0.1 2.9 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 PGA_cap PF09587.5 GAO82738.1 - 5.3e-71 238.8 0.2 6.4e-71 238.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap GATA PF00320.22 GAO82739.1 - 2.8e-30 103.3 19.4 5.7e-16 57.5 4.8 2.9 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 GAO82739.1 - 1.3e-05 24.3 3.1 0.0065 15.7 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 GAO82739.1 - 0.0023 17.0 7.6 0.15 11.3 0.3 2.9 2 1 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 GAO82739.1 - 0.0027 17.3 4.1 0.12 12.0 0.3 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.7 GAO82739.1 - 0.005 16.5 4.0 0.2 11.4 0.2 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 GAO82739.1 - 0.045 13.6 2.4 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.13 GAO82739.1 - 0.057 13.2 1.7 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 GAO82739.1 - 0.087 12.4 3.8 3.1 7.4 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 GAO82739.1 - 0.27 11.0 14.4 3.6 7.4 0.9 3.3 2 2 1 3 3 3 0 Double zinc ribbon HypA PF01155.14 GAO82739.1 - 0.85 9.3 2.2 6 6.5 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family COPI_assoc PF08507.5 GAO82740.1 - 2e-45 153.8 7.6 2.2e-45 153.7 5.3 1.0 1 0 0 1 1 1 1 COPI associated protein Bax1-I PF01027.15 GAO82740.1 - 0.0011 18.6 7.8 0.0014 18.2 5.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DAO PF01266.19 GAO82742.1 - 3.6e-22 78.7 0.4 1.6e-21 76.5 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO82742.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OTU PF02338.14 GAO82743.1 - 1.1e-13 51.8 0.0 4.4e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAO82743.1 - 0.11 11.8 0.1 3.8 6.8 0.0 2.6 2 1 0 2 2 2 0 Peptidase C65 Otubain MHYT PF03707.11 GAO82744.1 - 5.7e-09 35.9 21.7 1.2e-06 28.5 2.6 3.9 3 1 1 4 4 4 2 Bacterial signalling protein N terminal repeat Thioredoxin PF00085.15 GAO82745.1 - 2.8e-28 97.6 0.3 3.1e-28 97.5 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAO82745.1 - 3.9e-08 33.4 0.3 3.4e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 GAO82745.1 - 9.7e-05 21.9 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAO82745.1 - 0.00084 19.4 0.0 0.054 13.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 GAO82745.1 - 0.0014 18.5 0.1 0.0025 17.7 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 GAO82745.1 - 0.013 15.2 0.1 0.017 14.7 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 GAO82745.1 - 0.029 14.3 0.1 0.051 13.5 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.5 GAO82745.1 - 0.037 13.5 0.7 5 6.6 0.0 2.1 1 1 1 2 2 2 0 Redoxin IF-2B PF01008.12 GAO82747.1 - 2.1e-48 164.7 0.0 2.6e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 GAO82747.1 - 0.019 14.5 0.0 8.5 5.9 0.0 2.8 3 0 0 3 3 3 0 DeoR C terminal sensor domain Nuf2 PF03800.9 GAO82748.1 - 1.8e-46 157.7 2.3 2.6e-46 157.2 0.2 2.2 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 GAO82748.1 - 9.3 5.3 9.5 9 5.3 1.6 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Adaptin_N PF01602.15 GAO82749.1 - 1.8e-109 366.4 0.0 2.3e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 GAO82749.1 - 4.2e-11 42.9 0.0 0.00051 20.2 0.0 4.5 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 GAO82749.1 - 1.4e-08 34.0 0.0 0.044 13.8 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 GAO82749.1 - 0.0048 17.3 3.6 50 4.5 0.0 5.9 4 1 2 6 6 6 0 HEAT-like repeat Cnd1 PF12717.2 GAO82749.1 - 0.0056 16.5 0.0 3.5 7.4 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 GAO82749.1 - 0.021 14.8 0.1 2.2 8.3 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 GAO82749.1 - 0.084 12.2 0.4 13 5.0 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal BRK PF07533.11 GAO82749.1 - 0.23 10.9 1.1 3.5 7.1 0.0 2.9 3 1 0 3 3 3 0 BRK domain SpoIIIAH PF12685.2 GAO82749.1 - 0.28 10.6 11.9 16 4.9 7.3 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Arm PF00514.18 GAO82749.1 - 0.39 10.6 4.7 44 4.1 0.1 5.2 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Sporozoite_P67 PF05642.6 GAO82749.1 - 4.8 4.9 11.8 8.5 4.0 8.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Metallophos PF00149.23 GAO82750.1 - 2.6e-41 141.2 0.4 3.3e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 GAO82751.1 - 1.9e-60 203.7 0.1 2.1e-60 203.6 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Clp1 PF06807.9 GAO82752.1 - 5.5e-14 52.3 0.0 1.7e-08 34.4 0.0 2.8 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.12 GAO82752.1 - 1.3e-05 24.9 0.0 0.0001 21.9 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 GAO82752.1 - 2.8e-05 23.8 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 GAO82752.1 - 0.00012 21.9 0.0 0.00045 20.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.1 GAO82752.1 - 0.067 11.8 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 GAO82752.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Polysacc_deac_1 PF01522.16 GAO82753.1 - 2.7e-21 75.4 0.0 4.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 GAO82753.1 - 0.031 13.2 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase ADH_zinc_N PF00107.21 GAO82755.1 - 9.2e-33 112.5 0.0 1.7e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO82755.1 - 2.2e-21 77.0 0.0 4.9e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO82755.1 - 5.6e-10 38.9 0.0 1e-08 34.8 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 GAO82755.1 - 0.062 13.2 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Arb1 PF09692.5 GAO82756.1 - 7.8e-177 588.0 0.1 1e-176 587.6 0.1 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Pheromone PF08015.6 GAO82756.1 - 0.51 11.1 1.9 1.2 10.0 1.3 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF1179 PF06678.6 GAO82756.1 - 2.1 8.6 5.3 4.4 7.6 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Herpes_DNAp_acc PF04929.7 GAO82756.1 - 6 5.7 8.7 9.3 5.1 6.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor IPK PF03770.11 GAO82757.1 - 5.6e-62 208.8 0.0 8.6e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 GAO82758.1 - 1.6e-20 72.4 0.0 1.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 GAO82759.1 - 5.5e-24 83.7 0.1 8.8e-24 83.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DUF605 PF04652.11 GAO82759.1 - 6.2 6.1 10.8 7.9 5.7 7.5 1.2 1 0 0 1 1 1 0 Vta1 like TRF PF08558.5 GAO82760.1 - 3e-90 301.7 0.4 4.6e-90 301.1 0.3 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 GAO82760.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain His_Phos_2 PF00328.17 GAO82761.1 - 9e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4244 PF14029.1 GAO82761.1 - 0.096 11.7 2.7 0.079 12.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Pkinase PF00069.20 GAO82763.1 - 4e-70 235.9 0.0 6.1e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82763.1 - 4.6e-30 104.5 0.0 1.2e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO82763.1 - 8.7e-07 28.1 0.2 0.13 11.2 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 GAO82763.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO82763.1 - 0.11 12.2 0.0 5.7 6.5 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 GAO82764.1 - 5.3e-26 90.1 4.5 9.6e-26 89.2 3.1 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad3 Fibritin_C PF07921.7 GAO82764.1 - 0.058 13.3 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Fibritin C-terminal region TP_methylase PF00590.15 GAO82764.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Calici_MSP PF05752.6 GAO82764.1 - 1.1 8.8 5.6 0.44 10.1 2.4 1.4 2 0 0 2 2 2 0 Calicivirus minor structural protein Ribosomal_S5_C PF03719.10 GAO82765.1 - 4e-22 77.2 0.1 1.1e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 GAO82765.1 - 1.1e-07 31.4 0.0 4.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.6 GAO82766.1 - 1.5e-13 50.1 0.1 2.4e-06 26.5 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 GAO82766.1 - 3.7e-06 26.5 0.0 3.3e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain TRAM PF01938.15 GAO82766.1 - 4.9e-05 23.0 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 GAO82766.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 GAO82766.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 GAO82766.1 - 0.051 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAO82766.1 - 0.086 13.4 0.0 0.46 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ral PF11058.3 GAO82766.1 - 0.18 11.2 0.2 0.38 10.1 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Actin PF00022.14 GAO82767.1 - 1.9e-89 299.8 0.0 4.8e-89 298.5 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAO82767.1 - 0.027 13.0 0.0 1.1 7.8 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein Agglutinin PF07468.6 GAO82767.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Agglutinin Asparaginase_2 PF01112.13 GAO82768.1 - 1e-39 136.1 3.2 1.3e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 GAO82769.1 - 1.9e-121 404.5 0.0 2.2e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 GDPD PF03009.12 GAO82770.1 - 1e-72 244.7 0.0 3e-72 243.2 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 GAO82770.1 - 1.7e-30 105.2 0.1 1.5e-12 47.6 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 GAO82770.1 - 4.5e-30 105.3 6.2 5.2e-16 59.2 1.7 3.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 GAO82770.1 - 7.9e-27 93.1 0.8 1.4e-09 38.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 GAO82770.1 - 5.8e-26 88.9 2.6 9.9e-05 21.9 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAO82770.1 - 4.8e-18 64.7 1.2 4.8e-08 32.9 0.0 6.0 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO82770.1 - 5.9e-16 56.9 0.1 0.0013 18.7 0.0 6.3 5 0 0 5 5 5 4 Ankyrin repeat UNC45-central PF11701.3 GAO82771.1 - 6.7e-42 142.8 3.7 1.1e-41 142.0 0.2 3.1 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.18 GAO82771.1 - 2.1e-05 24.1 14.0 2.9 7.8 0.0 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 GAO82771.1 - 0.003 17.1 0.4 0.0093 15.5 0.3 1.9 1 0 0 1 1 1 1 TPR repeat Atx10homo_assoc PF09759.4 GAO82771.1 - 0.012 15.3 0.0 0.086 12.5 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain COQ7 PF03232.8 GAO82771.1 - 0.03 13.7 3.5 1.7 8.0 0.3 3.0 2 1 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 HEAT_2 PF13646.1 GAO82771.1 - 0.31 11.3 15.3 0.069 13.4 1.5 5.4 5 1 1 6 6 6 0 HEAT repeats PRMT5 PF05185.11 GAO82772.1 - 7.8e-173 575.4 0.0 1.1e-172 575.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 GAO82773.1 - 1.2e-27 96.0 0.1 7.1e-27 93.5 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAO82773.1 - 6.2e-25 87.1 0.0 1.8e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAO82773.1 - 3.4e-11 42.8 0.0 9.4e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO82773.1 - 6.4e-08 32.2 0.6 1.4e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO82773.1 - 1.3e-06 28.6 0.3 4.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAO82773.1 - 0.00012 21.5 0.3 0.00037 19.9 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 GAO82773.1 - 0.0015 18.3 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 GAO82773.1 - 0.0057 15.6 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 GAO82773.1 - 0.0065 16.2 0.2 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain TROVE PF05731.6 GAO82773.1 - 0.023 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 TROVE domain AAA_30 PF13604.1 GAO82773.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAO82773.1 - 0.072 12.5 0.1 5.1 6.4 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 GAO82773.1 - 0.083 12.8 0.0 0.43 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 GAO82773.1 - 0.16 11.4 0.0 0.57 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PPR_3 PF13812.1 GAO82774.1 - 0.038 14.2 0.0 0.37 11.1 0.0 2.8 1 1 0 1 1 1 0 Pentatricopeptide repeat domain DUF607 PF04678.8 GAO82774.1 - 0.2 11.5 1.3 0.75 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF607 EF-hand_6 PF13405.1 GAO82775.1 - 1.2e-09 37.1 0.3 0.001 18.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 GAO82775.1 - 7.1e-05 22.8 0.2 0.013 15.5 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 GAO82775.1 - 0.00073 18.6 0.0 0.0024 17.0 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 GAO82775.1 - 0.067 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 EF hand Met_10 PF02475.11 GAO82776.1 - 2.7e-05 23.8 0.0 7.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein WD40 PF00400.27 GAO82776.1 - 8.9e-05 22.2 1.3 0.0061 16.4 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAO82776.1 - 0.0036 16.1 0.0 0.0088 14.8 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region CNH PF00780.17 GAO82776.1 - 0.0073 15.7 0.1 0.73 9.2 0.1 2.4 2 0 0 2 2 2 1 CNH domain Methyltransf_26 PF13659.1 GAO82776.1 - 0.009 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAO82776.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Cupin_8 PF13621.1 GAO82777.1 - 3.9e-44 151.0 0.0 6e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 GAO82777.1 - 1e-14 54.4 0.0 2.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 GAO82777.1 - 6.5e-11 41.8 9.8 0.0012 18.5 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO82777.1 - 2.1e-06 27.5 0.0 0.00032 20.5 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAO82777.1 - 6e-05 23.0 4.8 3.2 8.0 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Cupin_4 PF08007.7 GAO82777.1 - 0.00093 18.5 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DSPc PF00782.15 GAO82778.1 - 2.9e-10 39.8 0.0 1.5e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain DNA_mis_repair PF01119.14 GAO82779.1 - 8.3e-34 115.5 0.2 1.4e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAO82779.1 - 3.8e-15 55.7 0.0 7.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAO82779.1 - 1.2e-11 44.2 0.0 3.2e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PC_rep PF01851.17 GAO82781.1 - 4.8e-16 57.9 17.8 3.5e-05 23.7 0.1 8.0 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAO82781.1 - 1.1e-06 28.8 0.7 0.44 10.8 0.1 4.3 3 3 0 3 3 3 3 HEAT repeats TPR_5 PF12688.2 GAO82781.1 - 0.031 14.3 1.1 4.7 7.2 0.0 3.6 3 1 0 4 4 4 0 Tetratrico peptide repeat DUF2776 PF10951.3 GAO82781.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) RIO1 PF01163.17 GAO82782.1 - 1.9e-42 144.7 0.3 8.4e-29 100.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 GAO82782.1 - 1.5e-32 111.4 0.0 4.5e-32 109.9 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 GAO82782.1 - 6e-08 32.7 0.0 0.00095 18.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAO82782.1 - 3e-06 26.4 0.0 0.00015 20.9 0.0 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.7 GAO82782.1 - 1.6 7.9 8.8 2.5 7.2 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L23 PF00276.15 GAO82783.1 - 6.2e-16 58.1 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.8 GAO82784.1 - 5.8e-69 231.4 0.2 1.4e-68 230.2 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAO82784.1 - 3.7e-25 88.8 0.2 9.9e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAO82784.1 - 2.2e-23 82.9 0.0 8.6e-23 80.9 0.0 2.1 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 GAO82784.1 - 5.6e-08 32.3 0.0 1.5e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 GAO82784.1 - 9.3e-08 31.8 0.0 3.2e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO82784.1 - 2.5e-07 30.8 0.5 1.1e-06 28.8 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_3 PF07726.6 GAO82784.1 - 5e-05 22.9 0.0 0.00015 21.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 GAO82784.1 - 5.6e-05 22.0 0.2 0.00048 18.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 GAO82784.1 - 5.6e-05 23.9 0.0 0.00021 22.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO82784.1 - 0.00015 21.3 0.0 0.00054 19.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 GAO82784.1 - 0.0002 20.5 0.0 0.0022 17.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAO82784.1 - 0.00031 20.6 0.1 0.0015 18.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 GAO82784.1 - 0.00038 20.5 0.0 0.0022 18.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAO82784.1 - 0.00071 19.5 0.1 0.0085 16.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAO82784.1 - 0.0013 18.1 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAO82784.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAO82784.1 - 0.0038 16.3 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_PrkA PF08298.6 GAO82784.1 - 0.019 13.6 0.1 0.51 8.9 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain PhoH PF02562.11 GAO82784.1 - 0.034 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 GAO82784.1 - 0.036 13.2 0.1 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 GAO82784.1 - 0.044 13.4 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAO82784.1 - 0.065 12.6 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAO82784.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAO82784.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 GAO82784.1 - 0.073 12.4 0.2 6.3 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 GAO82784.1 - 0.074 12.6 0.5 0.32 10.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 GAO82784.1 - 0.077 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAO82784.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 GAO82784.1 - 0.11 12.0 0.6 0.22 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 GAO82784.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.2 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.17 GAO82784.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 GAO82784.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.9 1 1 1 2 2 1 0 AAA domain CCDC-167 PF15188.1 GAO82784.1 - 6.9 6.6 13.6 0.21 11.5 1.1 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Porphobil_deam PF01379.15 GAO82785.1 - 1e-78 263.1 0.0 1.3e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAO82785.1 - 2.7e-19 69.0 0.3 4.7e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TAP42 PF04177.7 GAO82786.1 - 9.1e-108 360.2 7.3 1e-107 360.0 5.1 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.21 GAO82787.1 - 1.9e-39 134.6 0.0 2.2e-18 66.7 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAO82787.1 - 3.6e-20 72.2 0.0 2.2e-08 34.1 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 GAO82787.1 - 1e-16 60.4 0.1 7.7e-15 54.4 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 GAO82787.1 - 1.3e-11 44.2 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO82787.1 - 5.1e-11 42.7 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAO82787.1 - 8.9e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAO82787.1 - 0.051 12.5 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) dsrm PF00035.20 GAO82787.1 - 0.12 12.9 0.1 21 5.7 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif DHC_N1 PF08385.7 GAO82788.1 - 1.3e-190 634.6 1.6 1.3e-190 634.6 1.1 4.9 7 1 1 8 8 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 GAO82788.1 - 1.3e-130 435.5 5.8 1.3e-130 435.5 4.0 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 GAO82788.1 - 5e-109 365.3 0.0 1.2e-108 364.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 GAO82788.1 - 6.2e-79 264.7 0.0 2.2e-78 262.9 0.0 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 GAO82788.1 - 3.7e-44 150.2 0.0 2.2e-43 147.7 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 GAO82788.1 - 1e-41 142.7 0.7 1.6e-40 138.8 0.1 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 GAO82788.1 - 2.7e-41 141.4 8.5 4.7e-41 140.6 5.9 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 GAO82788.1 - 3.3e-33 114.3 0.3 9.8e-11 41.5 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 GAO82788.1 - 1.1e-20 73.9 0.2 7.7e-20 71.1 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 GAO82788.1 - 1.1e-16 61.2 0.1 0.0088 16.1 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA PF00004.24 GAO82788.1 - 2.1e-15 57.0 0.0 4.6e-05 23.6 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAO82788.1 - 2.1e-10 40.6 0.3 0.33 10.8 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA_17 PF13207.1 GAO82788.1 - 1.3e-09 38.9 0.0 0.041 14.6 0.0 5.7 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 GAO82788.1 - 1.5e-09 38.2 0.1 0.025 14.8 0.0 5.1 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 GAO82788.1 - 8.6e-08 31.4 0.0 0.02 13.7 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_14 PF13173.1 GAO82788.1 - 2.3e-06 27.5 0.0 0.2 11.5 0.0 5.5 6 0 0 6 6 5 1 AAA domain AAA_16 PF13191.1 GAO82788.1 - 4.6e-06 26.7 17.3 0.12 12.2 0.1 8.9 8 1 1 9 9 8 2 AAA ATPase domain ABC_tran PF00005.22 GAO82788.1 - 7.3e-06 26.3 0.4 1.2 9.3 0.0 5.3 4 0 0 4 4 4 2 ABC transporter AAA_29 PF13555.1 GAO82788.1 - 1.2e-05 24.6 0.0 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 GAO82788.1 - 1.6e-05 24.5 0.2 0.43 10.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 GAO82788.1 - 7.3e-05 22.0 0.8 0.44 9.6 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAO82788.1 - 0.00011 21.3 0.1 0.46 9.5 0.0 4.3 4 0 0 4 4 4 1 Zeta toxin RNA_helicase PF00910.17 GAO82788.1 - 0.011 15.8 0.2 21 5.3 0.0 4.4 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 GAO82788.1 - 0.018 14.7 0.3 13 5.4 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAO82788.1 - 0.46 9.8 6.4 0.7 9.2 0.0 3.9 5 0 0 5 5 4 0 AAA domain PduV-EutP PF10662.4 GAO82788.1 - 0.98 8.9 4.8 7 6.1 0.1 4.1 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation ERM PF00769.14 GAO82788.1 - 7.6 5.9 30.2 1.6 8.2 2.4 2.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Svf1 PF08622.5 GAO82789.1 - 3.2e-135 450.3 0.1 4e-135 449.9 0.1 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 GAO82789.1 - 3.8e-05 23.1 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Ribosomal_L11_N PF03946.9 GAO82790.1 - 9.5e-27 92.2 0.1 5.9e-26 89.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAO82790.1 - 1.3e-24 86.1 1.6 1.4e-24 85.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 GAO82791.1 - 1.5e-58 198.0 0.0 5.3e-58 196.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82791.1 - 8.6e-21 74.1 0.0 1.5e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO82791.1 - 0.019 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO82791.1 - 0.16 10.8 0.0 0.35 9.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAO82791.1 - 0.34 9.9 1.0 0.51 9.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.22 GAO82792.1 - 2.8e-43 145.5 1.8 2.6e-15 55.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3943 PF13084.1 GAO82792.1 - 0.041 13.4 0.1 0.088 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3943) Cupin_5 PF06172.6 GAO82793.1 - 4.3e-16 59.0 0.0 1.2e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Gemini_AC4_5 PF04807.7 GAO82793.1 - 0.15 11.5 0.7 0.29 10.6 0.5 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region DUF3337 PF11816.3 GAO82794.1 - 7.3e-111 370.7 0.0 3.3e-106 355.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) ATP_bind_3 PF01171.15 GAO82794.1 - 5e-34 117.3 0.0 4.1e-32 111.1 0.0 3.0 1 1 0 1 1 1 1 PP-loop family WD40 PF00400.27 GAO82794.1 - 6.9e-21 73.2 19.4 1.7e-07 30.8 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Asn_synthase PF00733.16 GAO82794.1 - 0.097 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 GAO82795.1 - 5.4e-23 81.8 0.0 1.4e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 GAO82795.1 - 1.2e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Cep57_CLD_2 PF14197.1 GAO82795.1 - 0.0024 17.7 3.3 0.055 13.4 0.6 3.1 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF904 PF06005.7 GAO82795.1 - 0.29 11.4 4.8 0.51 10.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Sec7 PF01369.15 GAO82796.1 - 1.7e-60 203.9 0.0 2.8e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAO82796.1 - 5.4e-20 71.4 0.0 2.4e-13 49.8 0.1 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_12 PF13424.1 GAO82797.1 - 1.4e-12 47.3 0.8 0.027 14.4 0.0 8.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO82797.1 - 3.2e-12 45.9 10.4 2.1 9.2 0.0 11.0 10 2 4 14 14 13 2 Tetratricopeptide repeat Suf PF05843.9 GAO82797.1 - 1.5e-11 44.5 9.2 0.024 14.3 0.0 5.9 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 GAO82797.1 - 1.8e-09 37.7 0.1 0.13 12.5 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO82797.1 - 2.7e-07 30.0 10.0 0.95 9.5 0.0 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO82797.1 - 1.2e-06 28.0 5.2 4 7.1 0.0 7.1 8 2 0 8 8 8 2 TPR repeat Mad3_BUB1_I PF08311.7 GAO82797.1 - 3.2e-06 26.9 11.0 1.4 8.7 0.1 6.9 6 1 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 GAO82797.1 - 9.1e-06 25.0 2.3 11 6.1 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAO82797.1 - 1.2e-05 24.7 3.1 0.72 9.7 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 GAO82797.1 - 0.00034 19.6 11.9 0.029 13.2 0.1 5.8 2 2 5 7 7 7 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 GAO82797.1 - 0.0042 17.1 5.6 0.27 11.5 0.0 5.7 8 0 0 8 8 7 1 Tetratricopeptide repeat HAT PF02184.11 GAO82797.1 - 0.0085 15.8 5.0 2.3 8.0 0.0 5.9 6 0 0 6 6 6 1 HAT (Half-A-TPR) repeat CKAP2_C PF15297.1 GAO82797.1 - 0.03 13.1 0.1 0.083 11.6 0.0 1.7 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TPR_6 PF13174.1 GAO82797.1 - 9 7.0 13.4 21 5.8 0.0 7.0 7 1 1 8 8 8 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 GAO82798.1 - 5e-65 218.7 2.4 7.2e-65 218.2 1.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D RRM_1 PF00076.17 GAO82799.1 - 5.9e-26 89.8 1.4 3.1e-12 45.9 0.5 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82799.1 - 4.1e-18 64.9 0.1 3.3e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82799.1 - 3.9e-17 61.9 0.1 1.8e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFCD_C PF12612.3 GAO82800.1 - 6e-41 140.0 2.1 8.3e-41 139.5 0.1 2.3 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 GAO82800.1 - 5.7e-05 23.3 6.9 0.78 10.0 0.1 5.9 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 GAO82800.1 - 0.00012 21.8 7.6 1.7 8.9 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat TFX_C PF14601.1 GAO82800.1 - 0.078 12.7 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Pkinase PF00069.20 GAO82801.1 - 7.8e-63 212.0 0.0 1.3e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82801.1 - 5.2e-35 120.7 0.0 8.9e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 GAO82801.1 - 2.1e-33 113.8 17.4 9.7e-19 66.8 4.4 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 GAO82801.1 - 2.1e-20 72.1 28.5 1.9e-11 43.4 6.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 GAO82801.1 - 2.4e-14 53.5 3.3 6.7e-14 52.1 2.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF605 PF04652.11 GAO82801.1 - 0.0039 16.6 13.0 0.0039 16.6 9.0 2.1 2 0 0 2 2 2 1 Vta1 like Kinase-like PF14531.1 GAO82801.1 - 0.021 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 GAO82801.1 - 2.4 8.1 6.9 0.38 10.7 0.9 2.3 2 0 0 2 2 2 0 Up-regulated During Septation MFS_1 PF07690.11 GAO82802.1 - 4.5e-24 84.8 42.5 9.2e-19 67.3 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO82802.1 - 2.5e-07 29.4 19.6 6.1e-05 21.5 3.8 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1049 PF06305.6 GAO82802.1 - 0.15 11.5 4.3 4 6.9 0.6 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) eIF-1a PF01176.14 GAO82803.1 - 6.8e-17 60.6 0.0 9.1e-17 60.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAS-barrel PF09378.5 GAO82803.1 - 0.079 12.8 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 HAS barrel domain ALG3 PF05208.8 GAO82804.1 - 5e-76 256.3 15.6 5.9e-41 140.9 5.9 2.1 1 1 1 2 2 2 2 ALG3 protein DUF2628 PF10947.3 GAO82804.1 - 2.1 8.1 8.9 5.5 6.8 6.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Metallophos PF00149.23 GAO82805.1 - 2e-36 125.3 0.2 2.7e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 GAO82806.1 - 3.2e-42 144.2 0.1 4.9e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ANTAR PF03861.9 GAO82806.1 - 0.2 11.2 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 ANTAR domain Tub_2 PF04525.7 GAO82807.1 - 6.5e-12 45.2 0.0 1.2e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Tubby C 2 DNA_ligase_A_M PF01068.16 GAO82809.1 - 8.2e-48 162.4 0.1 3.2e-46 157.2 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAO82809.1 - 3.8e-38 131.0 0.0 8.6e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAO82809.1 - 4.1e-18 65.5 0.0 2.6e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 GAO82809.1 - 2.1e-07 30.9 0.0 1.8e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 GAO82809.1 - 6.7e-05 22.5 0.1 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV Fungal_trans PF04082.13 GAO82810.1 - 2.8e-18 65.7 1.2 1.8e-17 63.0 0.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 GAO82811.1 - 4.6e-05 23.0 0.1 0.00011 21.8 0.0 1.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Zn_clus PF00172.13 GAO82812.1 - 4.2e-08 32.9 9.9 1e-07 31.7 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO82812.1 - 0.00049 19.0 5.4 0.0023 16.8 3.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spb1_C PF07780.7 GAO82814.1 - 4.7e-77 258.3 30.5 4.7e-77 258.3 21.2 3.7 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 GAO82814.1 - 1.6e-57 193.4 10.9 1.6e-57 193.4 7.5 4.5 4 1 0 4 4 4 2 Domain of unknown function (DUF3381) FtsJ PF01728.14 GAO82814.1 - 5.8e-54 182.8 0.0 1.3e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase YgaB PF14182.1 GAO82814.1 - 0.51 10.6 13.0 0.11 12.7 4.0 3.3 2 0 0 2 2 2 0 YgaB-like protein DOT1 PF08123.8 GAO82815.1 - 4.8e-76 254.6 0.0 6.7e-76 254.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 GAO82815.1 - 0.0002 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO82815.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sec8_exocyst PF04048.9 GAO82815.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Methyltransf_18 PF12847.2 GAO82815.1 - 0.048 14.2 0.1 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.6 GAO82815.1 - 2.5 6.7 7.7 4.4 5.8 5.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ATG16 PF08614.6 GAO82816.1 - 1.1e-40 139.5 7.7 2.3e-20 73.2 0.0 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 GAO82816.1 - 0.0036 16.9 3.3 0.0048 16.5 2.3 1.2 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 GAO82816.1 - 0.0085 15.1 6.9 0.012 14.6 4.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Nup54 PF13874.1 GAO82816.1 - 0.012 15.2 4.2 0.022 14.3 2.9 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MscS_porin PF12795.2 GAO82816.1 - 0.048 12.9 12.1 0.23 10.7 8.5 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain HR1 PF02185.11 GAO82816.1 - 0.068 12.9 0.6 0.068 12.9 0.4 2.0 2 0 0 2 2 2 0 Hr1 repeat Peptidase_S46 PF10459.4 GAO82816.1 - 0.069 11.5 0.4 0.07 11.5 0.3 1.0 1 0 0 1 1 1 0 Peptidase S46 KfrA_N PF11740.3 GAO82816.1 - 0.07 13.5 0.4 0.07 13.5 0.3 2.5 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term FliJ PF02050.11 GAO82816.1 - 0.091 12.8 9.5 2.3 8.3 6.0 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein OmpH PF03938.9 GAO82816.1 - 0.11 12.4 3.1 0.17 11.8 2.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Striatin PF08232.7 GAO82816.1 - 0.13 12.5 5.8 0.18 12.1 4.1 1.2 1 0 0 1 1 1 0 Striatin family PilJ PF13675.1 GAO82816.1 - 0.15 12.3 7.2 0.041 14.1 2.9 1.7 2 0 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Snapin_Pallidin PF14712.1 GAO82816.1 - 0.4 11.0 4.1 0.82 10.0 2.8 1.5 1 1 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 GAO82816.1 - 0.43 9.7 6.8 0.89 8.7 4.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding GreA_GreB_N PF03449.10 GAO82816.1 - 0.98 9.5 6.3 1 9.4 0.6 2.9 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal GrpE PF01025.14 GAO82816.1 - 1.3 8.5 6.9 2.9 7.4 4.5 1.6 1 1 1 2 2 2 0 GrpE DUF4164 PF13747.1 GAO82816.1 - 1.4 9.1 10.2 2.5 8.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GvpG PF05120.7 GAO82816.1 - 1.5 8.6 7.3 1 9.2 1.4 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Prefoldin_2 PF01920.15 GAO82816.1 - 1.9 8.2 6.0 2.7 7.8 0.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit FUSC PF04632.7 GAO82816.1 - 3.6 5.8 6.3 5 5.4 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC-167 PF15188.1 GAO82816.1 - 5.9 6.8 9.3 22 5.0 5.6 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 GAO82816.1 - 9.5 5.7 6.7 11 5.6 3.2 2.0 1 1 1 2 2 2 0 Septum formation initiator Ras PF00071.17 GAO82817.1 - 2.9e-54 182.8 0.1 3.5e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO82817.1 - 1.3e-18 67.6 0.0 2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO82817.1 - 2.4e-11 43.1 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAO82817.1 - 8.3e-07 28.9 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO82817.1 - 4.2e-06 26.3 0.0 0.00025 20.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAO82817.1 - 2.5e-05 23.5 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 GAO82817.1 - 0.00014 21.4 0.3 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 GAO82817.1 - 0.00065 18.9 0.1 0.0015 17.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO82817.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 GAO82817.1 - 0.0035 16.3 0.1 0.024 13.6 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 GAO82817.1 - 0.0039 16.8 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 GAO82817.1 - 0.0042 16.5 0.0 0.028 13.8 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 GAO82817.1 - 0.005 16.3 0.1 0.099 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 GAO82817.1 - 0.0059 16.3 0.4 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 GAO82817.1 - 0.0076 15.9 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAO82817.1 - 0.0084 15.5 0.1 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 GAO82817.1 - 0.019 14.9 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 GAO82817.1 - 0.022 14.4 0.1 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 GAO82817.1 - 0.072 12.3 0.0 0.098 11.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 GAO82817.1 - 0.087 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 GAO82817.1 - 0.11 12.6 0.2 0.27 11.4 0.2 1.9 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 GAO82817.1 - 0.14 11.3 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B EamA PF00892.15 GAO82818.1 - 4e-08 33.3 4.5 4e-08 33.3 3.1 3.3 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 GAO82818.1 - 1.4e-07 30.7 9.3 1.4e-07 30.7 6.4 1.5 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 GAO82818.1 - 3.5e-05 23.9 6.4 3.5e-05 23.9 4.5 3.9 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF914 PF06027.7 GAO82818.1 - 0.00015 20.7 9.3 0.00015 20.7 6.5 2.4 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 GAO82818.1 - 0.012 15.2 1.4 0.012 15.2 0.9 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family PH PF00169.24 GAO82819.1 - 2.5e-25 88.7 0.3 5.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 GAO82819.1 - 3.5e-14 53.0 0.7 5e-07 29.9 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 GAO82819.1 - 4.5e-11 42.9 0.6 3.8e-06 27.0 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 GAO82819.1 - 0.0066 16.5 0.1 0.088 12.8 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_transf_15 PF01793.11 GAO82820.1 - 3.6e-135 450.1 2.9 4.5e-135 449.8 2.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Phosducin PF02114.11 GAO82822.1 - 3.1e-15 55.6 0.0 5.1e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Phosducin Clathrin_lg_ch PF01086.12 GAO82822.1 - 4.9 7.0 14.0 77 3.0 9.7 2.1 1 1 0 1 1 1 0 Clathrin light chain Peptidase_S64 PF08192.6 GAO82822.1 - 5.1 5.2 6.0 6.4 4.9 4.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 WD40 PF00400.27 GAO82823.1 - 2.3e-52 173.0 21.6 1.5e-08 34.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAO82823.1 - 3.9e-05 23.4 0.0 0.082 12.6 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 GAO82823.1 - 0.38 9.9 1.2 0.56 9.3 0.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 zf-MYND PF01753.13 GAO82824.1 - 2.1e-07 30.6 20.4 2.1e-07 30.6 14.2 1.8 2 0 0 2 2 2 1 MYND finger DIOX_N PF14226.1 GAO82825.1 - 6.8e-20 71.7 0.0 9.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO82825.1 - 2.3e-13 50.2 0.0 5.7e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LVIVD PF08309.6 GAO82825.1 - 0.026 13.4 0.3 0.054 12.4 0.2 1.5 1 0 0 1 1 1 0 LVIVD repeat MKT1_C PF12246.3 GAO82826.1 - 1.3e-78 263.3 0.0 1.8e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 GAO82826.1 - 6e-32 109.8 0.5 1.3e-31 108.7 0.1 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 GAO82826.1 - 1.2e-13 50.9 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAO82826.1 - 7.9e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin PF00085.15 GAO82827.1 - 7e-64 212.0 0.3 7.2e-32 109.1 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 GAO82827.1 - 1.7e-26 92.6 2.7 1.7e-26 92.6 1.9 1.9 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 GAO82827.1 - 7.6e-22 77.6 0.4 9.4e-10 38.6 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAO82827.1 - 1.4e-16 60.2 0.0 2.8e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 GAO82827.1 - 1.7e-14 53.7 0.2 2.6e-05 24.2 0.0 4.3 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 GAO82827.1 - 2.4e-09 36.9 0.1 0.0017 18.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 GAO82827.1 - 3.9e-08 33.2 0.5 0.00032 20.5 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 GAO82827.1 - 2.9e-07 30.1 1.2 0.0063 16.0 0.0 2.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_9 PF14595.1 GAO82827.1 - 4.3e-05 23.0 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 GAO82827.1 - 4.9e-05 23.0 0.0 0.065 13.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.6 GAO82827.1 - 0.00057 19.7 0.0 0.071 13.0 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 GAO82827.1 - 0.0015 18.5 4.8 1.2 9.1 0.1 4.2 3 2 2 5 5 5 1 Thioredoxin DSBA PF01323.15 GAO82827.1 - 0.0026 17.3 1.1 5.7 6.4 0.0 4.0 3 1 1 4 4 4 1 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 GAO82827.1 - 0.0084 16.0 1.0 2.1 8.4 0.0 3.4 2 2 0 2 2 2 1 Glutaredoxin TraF PF13728.1 GAO82827.1 - 0.01 15.3 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Laps PF10169.4 GAO82827.1 - 0.04 14.1 2.4 0.11 12.7 0.2 2.7 2 1 1 3 3 3 0 Learning-associated protein DDE_Tnp_1_2 PF13586.1 GAO82827.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 Transposase DDE domain HSBP1 PF06825.7 GAO82828.1 - 6.2e-19 67.3 0.0 7.7e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 GAO82828.1 - 0.0012 18.1 0.7 0.42 10.0 0.0 2.2 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 GAO82828.1 - 0.012 15.4 0.4 0.014 15.2 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 GAO82828.1 - 0.014 15.6 0.2 0.02 15.1 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2937 PF11157.3 GAO82828.1 - 0.04 13.2 1.6 0.047 13.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) UPF0184 PF03670.8 GAO82828.1 - 0.068 13.3 0.8 0.11 12.7 0.6 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Apolipoprotein PF01442.13 GAO82828.1 - 0.072 12.5 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Corona_S2 PF01601.11 GAO82828.1 - 0.092 10.8 0.2 0.1 10.6 0.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Tup_N PF08581.5 GAO82828.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Tup N-terminal DUF935 PF06074.7 GAO82828.1 - 0.12 11.0 1.4 0.12 11.0 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF2572 PF10833.3 GAO82828.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Ebp2 PF05890.7 GAO82829.1 - 3.2e-93 311.9 19.0 3.2e-93 311.9 13.1 2.1 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TruB_N PF01509.13 GAO82831.1 - 1.8e-46 157.9 0.0 6.6e-46 156.1 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Ribosomal_L44 PF00935.14 GAO82831.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L44 OHCU_decarbox PF09349.5 GAO82833.1 - 4e-42 144.2 0.1 7.5e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.27 GAO82833.1 - 1.5e-31 107.1 8.8 5.6e-10 38.7 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat SRP9-21 PF05486.7 GAO82833.1 - 1e-29 102.1 0.4 3.1e-29 100.5 0.1 2.1 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 GAO82834.1 - 7.6e-122 405.7 1.0 9e-122 405.4 0.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.22 GAO82835.1 - 3.3e-56 186.9 3.3 4.2e-20 71.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 GAO82836.1 - 2.5e-15 55.6 10.8 9.7e-09 34.7 0.4 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAO82836.1 - 0.01 14.1 0.0 3.1 6.0 0.0 3.0 2 2 3 5 5 5 0 Cytochrome D1 heme domain Kelch_6 PF13964.1 GAO82836.1 - 0.025 14.7 0.1 0.64 10.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif DUF4613 PF15390.1 GAO82836.1 - 0.035 12.3 0.0 0.062 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3312 PF11768.3 GAO82836.1 - 0.055 11.6 0.0 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1308 PF07000.6 GAO82837.1 - 2.8e-113 378.2 0.0 3.7e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 GAO82838.1 - 1.1e-71 241.2 14.8 1.3e-71 240.9 10.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF2392 PF10288.4 GAO82839.1 - 9.7e-27 93.4 0.0 1.6e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF4112 PF13430.1 GAO82840.1 - 4.3e-35 119.8 0.6 5.8e-35 119.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 GAO82841.1 - 4.7e-35 119.3 0.4 8e-35 118.6 0.3 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 GAO82841.1 - 8.1e-17 61.1 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 GAO82842.1 - 2.9e-11 43.1 0.0 8.1e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAO82842.1 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 GAO82843.1 - 6e-20 70.7 1.0 2.8e-19 68.6 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 GAO82843.1 - 0.0039 16.7 0.1 0.024 14.2 0.2 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82843.1 - 0.027 14.4 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.6 GAO82843.1 - 6.4 4.9 20.4 0.2 9.8 8.0 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Mei4 PF13971.1 GAO82844.1 - 6.2e-05 22.1 1.9 6.2e-05 22.1 1.3 2.3 2 1 0 2 2 2 1 Meiosis-specific protein Mei4 KIAA1430 PF13879.1 GAO82844.1 - 0.01 16.2 2.4 0.01 16.2 1.7 2.1 2 0 0 2 2 2 0 KIAA1430 homologue HEPN PF05168.9 GAO82844.1 - 0.082 12.7 1.8 0.087 12.7 0.3 1.8 2 0 0 2 2 2 0 HEPN domain Amidohydro_2 PF04909.9 GAO82845.1 - 6.3e-31 107.9 6.2 1e-30 107.2 4.3 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 GAO82845.1 - 0.14 11.2 0.0 0.48 9.5 0.0 1.8 2 0 0 2 2 2 0 TatD related DNase DIOX_N PF14226.1 GAO82846.1 - 2.2e-23 82.9 0.0 5.4e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO82846.1 - 5.3e-17 61.9 0.0 1.7e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 GAO82847.1 - 2.1e-17 63.5 0.5 1.4e-15 57.6 0.3 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO82847.1 - 1.7e-14 54.1 0.0 1.5e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO82847.1 - 4.1e-07 29.8 0.8 5.8e-07 29.3 0.1 1.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAO82847.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAO82847.1 - 0.0042 16.5 0.0 0.0082 15.6 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAO82847.1 - 0.0043 17.0 0.1 0.0065 16.4 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain DUF1776 PF08643.5 GAO82847.1 - 0.0072 15.5 0.0 0.014 14.5 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 GAO82847.1 - 0.016 14.1 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAO82847.1 - 0.02 13.6 0.1 0.034 12.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DASH_Duo1 PF08651.5 GAO82847.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Saccharop_dh PF03435.13 GAO82847.1 - 0.075 11.9 0.2 0.13 11.2 0.1 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase Ferritin_2 PF13668.1 GAO82848.1 - 5.3e-18 65.2 0.2 7.8e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain MeMO_Hyd_G PF02964.11 GAO82849.1 - 0.037 13.9 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain AMP-binding PF00501.23 GAO82850.1 - 2.3e-63 214.0 0.0 3.2e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO82850.1 - 4.4e-14 53.1 0.6 1.4e-13 51.5 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Syndecan PF01034.15 GAO82851.1 - 0.064 12.9 0.2 0.064 12.9 0.1 2.4 3 0 0 3 3 3 0 Syndecan domain DUF4149 PF13664.1 GAO82851.1 - 0.93 9.5 8.0 0.78 9.8 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) LDB19 PF13002.2 GAO82852.1 - 7.7e-60 201.6 0.1 1.5e-59 200.7 0.1 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 GAO82852.1 - 6.6e-08 32.5 0.6 4.4e-07 29.8 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 GAO82852.1 - 0.058 13.4 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) PIG-L PF02585.12 GAO82853.1 - 1.8e-31 109.3 0.1 2.7e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 GAO82854.1 - 1.2e-29 102.2 0.0 2.1e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.1 GAO82854.1 - 2.5e-05 24.2 0.6 0.91 9.9 0.0 4.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAO82854.1 - 0.00065 19.6 0.1 1.5 8.8 0.0 2.9 2 0 0 2 2 2 2 PPR repeat family DASH_Ask1 PF08655.5 GAO82854.1 - 0.13 12.1 0.4 16 5.3 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Ask1 GTP_EFTU PF00009.22 GAO82855.1 - 1.6e-21 76.5 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAO82855.1 - 8e-15 54.8 0.0 1.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain LSM PF01423.17 GAO82855.1 - 4.3e-12 45.3 0.0 1.3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 LSM domain GTP_EFTU_D2 PF03144.20 GAO82855.1 - 2.1e-06 27.7 1.7 9.6e-06 25.6 0.7 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 GAO82855.1 - 0.0008 18.9 0.6 0.19 11.2 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 GAO82855.1 - 0.014 15.8 0.1 0.27 11.7 0.1 2.9 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 GAO82855.1 - 0.12 12.3 0.1 0.38 10.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO82855.1 - 0.12 12.1 0.8 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Macoilin PF09726.4 GAO82856.1 - 5.4 5.1 7.6 6 5.0 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 GAO82857.1 - 7.3e-71 238.4 0.0 1e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAO82857.1 - 4.5e-23 81.2 0.0 8.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAO82857.1 - 9.8e-14 50.9 0.0 2.5e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAO82857.1 - 1.5e-07 31.2 8.8 2.9e-07 30.3 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO82857.1 - 5.8e-06 25.8 6.1 9.8e-06 25.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO82857.1 - 0.00033 20.2 8.0 0.00063 19.3 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO82857.1 - 0.0011 18.7 7.6 0.0022 17.7 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAO82857.1 - 0.0016 18.0 6.3 0.0032 17.1 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 GAO82857.1 - 0.084 12.4 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain zf-RING_UBOX PF13445.1 GAO82857.1 - 0.14 11.8 5.5 0.39 10.4 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAO82857.1 - 0.18 11.6 8.2 0.37 10.7 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.14 GAO82858.1 - 4.9e-46 157.1 0.0 6.8e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 GAO82859.1 - 2.5e-28 98.9 6.4 8.8e-19 67.6 0.6 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1645 PF07816.6 GAO82859.1 - 1.1 9.6 15.2 0.044 14.2 5.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DNA_pol_A PF00476.15 GAO82860.1 - 4.5e-101 338.2 0.0 6.5e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 GAO82860.1 - 0.0037 16.7 0.1 0.19 11.2 0.1 2.7 1 1 0 1 1 1 1 3'-5' exonuclease UPF0052 PF01933.13 GAO82861.1 - 1.4e-54 185.5 0.0 1.7e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 TAN PF11640.3 GAO82862.1 - 3.4e-47 160.0 3.0 7.4e-47 158.9 1.1 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 GAO82862.1 - 3.9e-46 157.4 0.1 1.2e-45 155.7 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 GAO82862.1 - 1.2e-12 47.0 0.1 3.6e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 GAO82863.1 - 0 1660.8 18.1 0 1660.4 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 GAO82864.1 - 5.2e-122 408.3 0.0 7.2e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAO82864.1 - 6.5e-25 86.7 1.9 1.5e-24 85.5 1.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Dak1 PF02733.12 GAO82865.1 - 1.2e-114 382.3 0.2 1.8e-114 381.6 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAO82865.1 - 1.3e-45 155.1 1.1 2.3e-45 154.3 0.8 1.4 1 0 0 1 1 1 1 DAK2 domain adh_short PF00106.20 GAO82866.1 - 5.5e-11 42.6 0.6 1.2e-10 41.5 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAO82866.1 - 3.5e-06 26.6 0.1 0.07 12.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAO82866.1 - 5.7e-05 23.0 0.1 8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO82866.1 - 0.00096 18.8 0.1 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 GAO82866.1 - 0.0054 16.7 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain UDPGT PF00201.13 GAO82867.1 - 4.5e-20 71.6 0.0 1.2e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 GAO82867.1 - 4.7e-08 32.6 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 GAO82867.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Lactamase_B PF00753.22 GAO82869.1 - 0.00059 19.5 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Kelch_3 PF13415.1 GAO82870.1 - 1.6e-30 104.5 11.4 2.6e-06 27.4 0.1 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAO82870.1 - 4.2e-26 90.4 10.1 7.3e-14 51.2 0.1 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO82870.1 - 8.1e-15 54.3 0.6 0.018 15.0 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 GAO82870.1 - 2.2e-13 49.7 0.3 0.0083 16.2 0.0 5.5 6 1 1 7 7 7 3 Kelch motif Kelch_2 PF07646.10 GAO82870.1 - 1.4e-09 37.3 5.8 0.035 13.8 0.2 6.1 6 2 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAO82870.1 - 2.3e-08 33.4 0.9 0.14 11.6 0.0 5.1 6 1 0 6 6 6 3 Kelch motif ECH_C PF13766.1 GAO82871.1 - 8.7e-41 138.7 0.5 2.1e-40 137.5 0.4 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAO82871.1 - 2.2e-25 89.2 0.1 9.8e-24 83.8 0.0 2.2 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 GAO82872.1 - 4.6e-46 156.6 0.0 5.4e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family BDV_P24 PF06595.6 GAO82872.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein Toxin_57 PF15535.1 GAO82872.1 - 0.12 12.4 0.6 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Putative toxin 57 PBP PF01161.15 GAO82873.1 - 6e-11 42.3 0.0 9.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1264 PF06884.6 GAO82874.1 - 1.5e-76 255.6 0.0 2.6e-76 254.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Las1 PF04031.8 GAO82874.1 - 2.5e-47 160.4 0.0 7.2e-47 158.8 0.0 1.9 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 GAO82874.1 - 2.5e-32 112.1 0.5 5e-32 111.1 0.4 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fungal_trans PF04082.13 GAO82874.1 - 1.1e-08 34.2 1.6 2.9e-08 32.9 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lactamase_B_2 PF12706.2 GAO82874.1 - 2.4e-05 23.9 0.1 7.4e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_S24 PF00717.18 GAO82874.1 - 0.00032 20.2 0.1 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAO82874.1 - 0.0044 16.5 0.0 0.037 13.5 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 BcrAD_BadFG PF01869.15 GAO82874.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Methyltransf_24 PF13578.1 GAO82875.1 - 2.5e-12 47.5 0.0 4.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 GAO82875.1 - 0.00028 20.0 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO82875.1 - 0.0031 18.0 0.0 0.0054 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4492 PF14899.1 GAO82875.1 - 0.13 11.7 1.0 0.44 10.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) GTP_EFTU PF00009.22 GAO82877.1 - 4.5e-44 150.1 0.0 5.9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAO82877.1 - 3.8e-25 87.9 0.0 9.3e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAO82877.1 - 5.7e-14 51.9 2.0 1.6e-13 50.5 1.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO82877.1 - 5.2e-05 23.1 0.0 8.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAO82877.1 - 0.0003 20.3 0.1 0.0007 19.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 cobW PF02492.14 GAO82877.1 - 0.021 14.2 0.1 0.047 13.1 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 GAO82877.1 - 0.065 12.7 0.0 7.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Miro PF08477.8 GAO82877.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein NAD_kinase PF01513.16 GAO82878.1 - 1.1e-67 227.7 0.0 1.7e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 GAO82879.1 - 1.3e-36 125.3 0.0 1.8e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 GAO82880.1 - 2.5e-47 161.4 33.5 2.5e-47 161.4 23.2 2.6 2 1 0 3 3 3 1 Splicing factor, Prp19-binding domain Rep_fac-A_3 PF08661.6 GAO82881.1 - 1.2e-31 108.8 0.0 1.4e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.22 GAO82882.1 - 2.7e-05 23.4 4.7 0.00059 19.1 0.4 2.6 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 GAO82883.1 - 4.1e-19 67.8 0.1 5.7e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 GAO82883.1 - 0.027 13.1 0.0 0.03 12.9 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Lyase_1 PF00206.15 GAO82883.1 - 0.067 12.3 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Lyase FPN1 PF06963.7 GAO82884.1 - 4.1e-142 473.5 10.0 5.3e-142 473.2 7.0 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Fungal_trans_2 PF11951.3 GAO82884.1 - 2.5e-09 36.2 0.3 7.2e-09 34.7 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 GAO82885.1 - 2e-77 260.3 0.0 2.6e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 GAO82885.1 - 0.034 14.4 0.1 0.92 9.7 0.1 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 GAO82886.1 - 6.9e-106 354.5 13.5 7.9e-106 354.3 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO82886.1 - 2.8e-20 72.3 27.1 2.8e-20 72.3 18.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.16 GAO82887.1 - 2e-09 37.2 14.0 3.4e-09 36.5 9.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO82887.1 - 3.4e-05 23.5 15.0 7.1e-05 22.5 10.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAO82887.1 - 0.0035 17.5 15.2 0.0067 16.6 10.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ABC_tran_2 PF12848.2 GAO82887.1 - 0.12 12.2 16.7 0.1 12.4 7.1 2.2 1 1 1 2 2 2 0 ABC transporter Transcrip_act PF04949.8 GAO82887.1 - 0.19 11.3 8.7 1.9 8.0 1.1 2.2 1 1 1 2 2 2 0 Transcriptional activator IncA PF04156.9 GAO82887.1 - 0.95 9.0 9.1 1.4 8.5 6.3 1.2 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 GAO82887.1 - 1.3 8.7 10.1 1.9 8.0 7.0 1.3 1 0 0 1 1 1 0 Mnd1 family Ead_Ea22 PF13935.1 GAO82887.1 - 3.4 7.9 8.5 4.8 7.5 5.5 1.5 1 1 0 1 1 1 0 Ead/Ea22-like protein Phe_hydrox_dim PF07976.7 GAO82888.1 - 0.15 11.6 0.6 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain CBS PF00571.23 GAO82889.1 - 4.7e-22 77.5 5.2 9.2e-11 41.3 0.0 3.6 4 0 0 4 4 4 3 CBS domain DUF1627 PF07789.7 GAO82889.1 - 0.23 11.0 1.5 0.44 10.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Mucin PF01456.12 GAO82889.1 - 3.2 7.5 19.4 5.5 6.7 13.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CRAL_TRIO PF00650.15 GAO82890.1 - 5.7e-38 129.8 0.0 8.1e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO82890.1 - 9.6e-14 51.2 0.0 2.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAO82890.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 GAO82891.1 - 5.7e-69 232.4 0.0 7.9e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 GAO82891.1 - 5.6e-38 130.3 0.1 7.9e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 GAO82892.1 - 3.4e-11 42.9 0.2 4.7e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Apc13p protein Kinesin PF00225.18 GAO82893.1 - 1.1e-113 379.3 0.8 1.5e-113 378.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain IF-2B PF01008.12 GAO82893.1 - 1.9e-74 250.2 0.3 1.9e-74 250.2 0.2 1.7 2 0 0 2 2 2 1 Initiation factor 2 subunit family RhgB_N PF09284.5 GAO82893.1 - 0.025 13.9 0.3 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 Rhamnogalacturonase B, N-terminal DUF87 PF01935.12 GAO82893.1 - 1 9.0 4.8 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 GAO82893.1 - 2.6 5.8 5.2 4.2 5.1 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Big_3 PF07523.7 GAO82894.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) DUF3449 PF11931.3 GAO82894.1 - 0.13 11.8 0.9 0.14 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF1275 PF06912.6 GAO82895.1 - 3.7e-46 156.9 15.3 4.5e-46 156.6 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.6 GAO82895.1 - 0.048 13.4 1.5 0.35 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Fungal_trans_2 PF11951.3 GAO82897.1 - 3.7e-54 183.7 2.7 7.5e-54 182.7 1.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO82897.1 - 0.0038 17.1 5.5 0.0091 15.8 3.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.7 GAO82897.1 - 0.026 14.5 1.7 0.06 13.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Amb_V_allergen PF03913.8 GAO82897.1 - 2.5 7.9 7.4 4.6 7.0 5.2 1.4 1 0 0 1 1 1 0 Amb V Allergen Closter_coat PF01785.12 GAO82898.1 - 0.043 12.8 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Closterovirus coat protein Mannosyl_trans3 PF11051.3 GAO82900.1 - 2.5e-79 266.4 0.0 1.2e-78 264.2 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative BCIP PF13862.1 GAO82902.1 - 1.1e-75 253.4 0.1 5.5e-75 251.1 0.0 2.0 2 0 0 2 2 2 1 p21-C-terminal region-binding protein CMD PF02627.15 GAO82902.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family CM_2 PF01817.16 GAO82903.1 - 1.4e-11 44.2 0.1 1.3e-06 28.3 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II DUF917 PF06032.7 GAO82903.1 - 0.06 11.8 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF917) WD40 PF00400.27 GAO82904.1 - 1.4e-38 129.3 4.6 1.3e-09 37.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAO82904.1 - 1.6e-06 26.5 8.8 0.077 11.1 0.3 4.8 2 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 GAO82904.1 - 0.0039 16.3 0.4 0.0061 15.6 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 End3 PF12761.2 GAO82904.1 - 0.018 14.6 0.8 0.043 13.4 0.3 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 BBS2_Mid PF14783.1 GAO82904.1 - 0.11 12.2 0.0 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Sad1_UNC PF07738.8 GAO82905.1 - 1.4e-13 50.7 0.0 2.4e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal RNase_H PF00075.19 GAO82906.1 - 0.065 13.5 0.1 0.086 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase H MFS_1 PF07690.11 GAO82907.1 - 4.8e-34 117.6 39.4 1.5e-32 112.7 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82907.1 - 3.5e-10 39.0 10.5 3.5e-10 39.0 7.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO82907.1 - 0.00044 18.5 4.1 0.001 17.3 2.8 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 GAO82907.1 - 2.5 8.1 9.2 0.26 11.3 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) MatE PF01554.13 GAO82908.1 - 7.7e-55 184.9 16.3 3.1e-30 104.9 1.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 GAO82908.1 - 1.4e-07 31.4 7.2 1.4e-07 31.4 5.0 3.6 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 GAO82908.1 - 0.0072 15.8 0.9 0.0072 15.8 0.6 2.5 3 0 0 3 3 3 1 Interferon-induced transmembrane protein DUF2269 PF10027.4 GAO82908.1 - 0.016 14.9 2.6 0.016 14.9 1.8 3.0 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2269) Arginase PF00491.16 GAO82909.1 - 1.8e-73 247.2 0.0 2.5e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAO82909.1 - 0.064 13.4 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Kinesin PF00225.18 GAO82910.1 - 4.1e-92 308.4 0.0 4.1e-92 308.4 0.0 3.3 3 1 0 4 4 4 1 Kinesin motor domain WD40_alt PF14077.1 GAO82910.1 - 0.0019 17.7 2.5 0.14 11.8 0.2 3.9 2 0 0 2 2 2 1 Alternative WD40 repeat motif Glycos_transf_1 PF00534.15 GAO82911.1 - 5.1e-30 104.1 0.0 7.9e-29 100.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 4HBT PF03061.17 GAO82911.1 - 1.7e-12 47.2 0.2 4.7e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_transf_4 PF13439.1 GAO82911.1 - 8.3e-11 41.9 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 GAO82911.1 - 2.6e-08 34.1 1.0 7.3e-08 32.7 0.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 GAO82911.1 - 3.4e-07 30.4 0.1 2.4e-05 24.5 0.1 2.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAO82911.1 - 0.0039 17.4 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ERCC4 PF02732.10 GAO82912.1 - 2e-27 95.7 0.0 3.8e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DDRGK PF09756.4 GAO82912.1 - 0.019 14.3 12.7 0.036 13.4 8.8 1.4 1 0 0 1 1 1 0 DDRGK domain SprA-related PF12118.3 GAO82912.1 - 1 8.6 18.8 0.028 13.7 8.7 1.5 2 0 0 2 2 2 0 SprA-related family Ycf1 PF05758.7 GAO82912.1 - 5.4 4.6 9.9 7.9 4.0 6.8 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 GAO82912.1 - 8.3 6.2 13.8 14 5.4 9.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.11 GAO82913.1 - 9.8e-18 63.9 12.2 9.8e-18 63.9 8.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 GAO82913.1 - 1.7e-05 24.1 0.7 1.7e-05 24.1 0.5 2.1 2 0 0 2 2 2 1 Nodulin-like PVL_ORF50 PF07768.6 GAO82913.1 - 0.053 13.5 0.3 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family IncA PF04156.9 GAO82913.1 - 0.72 9.4 0.0 0.72 9.4 0.0 2.8 5 0 0 5 5 5 0 IncA protein IPK PF03770.11 GAO82914.1 - 5.8e-62 208.8 0.0 9.5e-62 208.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 GAO82914.1 - 0.03 14.0 0.1 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 PLAC8 PF04749.12 GAO82915.1 - 3.4e-22 79.0 16.5 4.9e-22 78.4 11.4 1.2 1 0 0 1 1 1 1 PLAC8 family Integrin_b_cyt PF08725.6 GAO82915.1 - 0.012 15.0 0.7 0.064 12.6 0.1 2.4 3 0 0 3 3 3 0 Integrin beta cytoplasmic domain PalH PF08733.5 GAO82916.1 - 1.7e-102 342.8 0.0 3e-102 342.0 0.0 1.4 1 1 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.1 GAO82916.1 - 0.56 10.2 3.2 3.7 7.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 GAO82918.1 - 5.5e-39 133.8 30.7 1.8e-38 132.1 20.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MotA_ExbB PF01618.11 GAO82918.1 - 0.074 12.6 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Asp PF00026.18 GAO82919.1 - 1.7e-77 260.8 10.7 2.1e-77 260.5 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAO82919.1 - 4.1e-06 27.2 0.8 0.00082 19.8 0.1 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 GAO82919.1 - 7.3e-06 26.0 1.1 6.3e-05 22.9 0.7 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAO82919.1 - 0.011 15.2 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Zn_clus PF00172.13 GAO82920.1 - 4.6e-07 29.6 14.8 7e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.4 GAO82921.1 - 1.3e-24 86.6 0.3 1.9e-24 86.1 0.2 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 GAO82921.1 - 0.0002 20.5 0.0 0.00048 19.2 0.0 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 Nup88 PF10168.4 GAO82921.1 - 0.8 7.4 4.6 1.2 6.8 3.2 1.1 1 0 0 1 1 1 0 Nuclear pore component Mhr1 PF12829.2 GAO82922.1 - 1.3e-31 108.2 0.2 3.4e-31 106.9 0.2 1.8 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination REV PF00424.13 GAO82922.1 - 0.05 13.5 1.2 0.12 12.2 0.8 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PP2C PF00481.16 GAO82923.1 - 2.7e-66 223.5 0.0 3.3e-53 180.7 0.1 3.2 1 1 1 2 2 2 2 Protein phosphatase 2C Pro_isomerase PF00160.16 GAO82924.1 - 1.8e-40 138.7 0.0 3.1e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 GAO82924.1 - 2.1e-06 27.1 0.0 8.1e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 GAO82924.1 - 3e-05 23.8 0.1 0.00024 21.0 0.0 2.4 1 1 1 2 2 2 1 U-box domain MSA-2c PF12238.3 GAO82924.1 - 2.2 7.8 7.9 1.3 8.6 1.7 2.5 2 1 0 2 2 2 0 Merozoite surface antigen 2c YjeF_N PF03853.10 GAO82925.1 - 9.4e-38 129.4 0.1 1.4e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 GAO82925.1 - 2.7e-11 43.9 1.2 2.7e-11 43.9 0.9 2.6 2 1 0 2 2 2 1 FDF domain Glyco_transf_4 PF13439.1 GAO82925.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PIF1 PF05970.9 GAO82926.1 - 1.3e-68 231.5 0.0 9.7e-52 176.0 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 GAO82926.1 - 4.2e-20 72.1 0.0 7.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO82926.1 - 2.1e-08 34.3 0.0 9.2e-08 32.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 GAO82926.1 - 2.7e-05 24.2 0.5 0.00035 20.6 0.1 2.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 GAO82926.1 - 5.8e-05 21.0 0.2 0.00054 17.8 0.0 2.3 3 0 0 3 3 3 1 Helicase AAA_19 PF13245.1 GAO82926.1 - 8e-05 22.3 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 GAO82926.1 - 0.00058 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAO82926.1 - 0.0013 17.7 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 GAO82926.1 - 0.0016 18.0 0.2 2.4 7.5 0.1 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 GAO82926.1 - 0.0016 18.3 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO82926.1 - 0.0023 17.9 0.9 0.0067 16.4 0.0 2.3 4 0 0 4 4 2 1 AAA ATPase domain DUF2075 PF09848.4 GAO82926.1 - 0.0035 16.3 0.0 0.0074 15.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 GAO82926.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase TrwB_AAD_bind PF10412.4 GAO82926.1 - 0.006 15.2 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 GAO82926.1 - 0.012 15.1 0.3 0.46 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 GAO82926.1 - 0.015 14.5 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_ab PF00006.20 GAO82926.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 GAO82926.1 - 0.038 13.6 0.4 0.13 11.9 0.3 1.8 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 GAO82926.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 GAO82926.1 - 0.043 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.16 GAO82926.1 - 0.082 12.1 0.1 0.082 12.1 0.1 2.1 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.9 GAO82926.1 - 0.1 12.3 0.5 0.89 9.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 GAO82926.1 - 0.1 12.1 0.0 0.1 12.1 0.0 3.0 1 1 2 3 3 3 0 AAA domain MobB PF03205.9 GAO82926.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAO82926.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAO82926.1 - 0.4 10.9 2.1 0.59 10.4 0.2 2.5 2 1 0 2 2 1 0 ABC transporter PTCB-BRCT PF12738.2 GAO82927.1 - 1.8e-42 143.0 1.3 2.3e-22 78.6 0.1 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 GAO82927.1 - 4.2e-26 90.9 0.1 8.9e-14 51.4 0.0 3.9 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain Dynamin_N PF00350.18 GAO82928.1 - 3.9e-17 62.5 0.1 8.5e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAO82928.1 - 7.5e-10 38.7 0.4 3.4e-09 36.6 0.2 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO82928.1 - 1.2e-06 28.1 0.6 1.4e-05 24.6 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 GAO82928.1 - 0.011 16.1 0.1 0.45 11.0 0.1 2.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 GAO82928.1 - 0.034 13.6 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.16 GAO82929.1 - 2.1e-34 118.3 20.0 3.1e-34 117.8 13.1 1.7 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 GAO82929.1 - 0.0096 13.8 2.6 0.011 13.6 1.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 GAO82929.1 - 0.053 12.9 5.3 0.079 12.3 3.7 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 GAO82929.1 - 5.1 7.1 18.0 7.9 6.5 7.6 2.2 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.7 GAO82929.1 - 7.7 6.2 11.3 21 4.8 7.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 GAO82930.1 - 5.5e-23 81.4 0.0 8.8e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO82930.1 - 1.3e-09 37.5 0.3 6.1e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase BBS1 PF14779.1 GAO82931.1 - 0.037 13.0 0.2 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 TIM PF00121.13 GAO82932.1 - 2.5e-93 311.6 0.7 2.8e-93 311.4 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 GAO82932.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 CutC family Dak1_2 PF13684.1 GAO82932.1 - 0.041 12.8 0.5 0.097 11.5 0.2 1.6 1 1 1 2 2 2 0 Dihydroxyacetone kinase family DeoRC PF00455.17 GAO82932.1 - 0.052 13.1 0.1 0.87 9.2 0.0 2.6 2 1 1 3 3 3 0 DeoR C terminal sensor domain DUF3722 PF12519.3 GAO82933.1 - 6.5e-85 284.4 4.9 8.7e-85 284.0 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) DUF3446 PF11928.3 GAO82933.1 - 6.1 7.1 18.2 5.4 7.2 5.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Ribosomal_L10 PF00466.15 GAO82934.1 - 1.6e-17 63.2 0.0 3.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 GAO82935.1 - 3.3e-34 117.0 1.4 6.2e-34 116.1 1.0 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 GAO82935.1 - 1.4e-16 59.8 0.0 3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82935.1 - 6.3e-11 42.1 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO82935.1 - 1.4e-07 31.2 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 GAO82936.1 - 6.5e-16 57.8 0.1 1.8e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Prp19 PF08606.6 GAO82937.1 - 1.7e-33 114.1 1.8 3e-33 113.3 1.3 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 GAO82937.1 - 3e-17 61.7 0.9 5.3e-05 22.9 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAO82937.1 - 6.3e-10 38.4 0.1 4.1e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region U-box PF04564.10 GAO82937.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain eIF2A PF08662.6 GAO82937.1 - 2e-05 24.3 0.3 0.0022 17.7 0.0 3.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 GAO82937.1 - 0.0043 15.3 0.0 0.048 11.8 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) zf-Nse PF11789.3 GAO82937.1 - 0.026 14.0 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PQQ_3 PF13570.1 GAO82937.1 - 2.2 8.6 6.8 6.8 7.1 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain DUF4604 PF15377.1 GAO82938.1 - 8.1e-26 91.1 19.9 9.6e-26 90.8 13.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) UPF0560 PF10577.4 GAO82938.1 - 4 5.5 8.5 4.6 5.3 5.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FLO_LFY PF01698.11 GAO82938.1 - 4.3 6.0 11.7 5.2 5.8 8.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein GTP_EFTU PF00009.22 GAO82939.1 - 2.1e-53 180.5 0.0 3.5e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAO82939.1 - 5.7e-16 58.1 0.0 1.4e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO82939.1 - 5.9e-09 35.9 0.0 3.2e-08 33.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAO82939.1 - 1.2e-07 31.4 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAO82939.1 - 0.0017 17.9 0.1 0.05 13.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor G, domain IV EXOSC1 PF10447.4 GAO82940.1 - 5.2e-28 96.8 0.7 5.2e-28 96.8 0.5 1.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 GAO82940.1 - 2.3e-15 55.5 0.1 4.7e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.18 GAO82941.1 - 9.9e-71 231.4 31.2 2.8e-13 49.1 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAO82941.1 - 1.4e-24 86.2 13.1 3.2e-07 30.5 0.3 7.4 2 2 4 7 7 7 7 HEAT repeats HEAT PF02985.17 GAO82941.1 - 2.2e-20 70.8 18.8 0.017 15.1 0.0 10.1 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 GAO82941.1 - 1.5e-15 57.1 14.5 0.0058 17.0 0.1 8.5 6 2 4 10 10 10 6 HEAT-like repeat Arm_2 PF04826.8 GAO82941.1 - 1.1e-11 44.3 6.7 0.0028 16.8 0.1 3.4 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 GAO82941.1 - 2.4e-11 42.6 7.8 5.1e-07 28.3 0.3 3.0 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 GAO82941.1 - 4.7e-10 38.0 0.3 9.2e-10 37.1 0.2 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 GAO82941.1 - 4.2e-09 35.9 0.4 0.00017 20.7 0.3 3.2 2 1 1 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.11 GAO82941.1 - 0.0058 16.9 7.4 5.4 7.7 0.2 6.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAO82941.1 - 0.0072 16.6 0.1 2.3 8.6 0.0 3.6 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 GAO82941.1 - 0.017 14.7 0.4 0.33 10.6 0.1 2.9 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 GAO82941.1 - 0.44 8.7 6.3 1.3 7.1 1.1 2.9 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit FHA PF00498.21 GAO82943.1 - 3.6e-14 52.6 0.0 6.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 GAO82943.1 - 3.7e-06 26.6 9.4 6.6e-06 25.8 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO82943.1 - 0.0012 18.9 6.3 0.0024 17.9 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAO82943.1 - 0.0055 16.4 6.6 0.01 15.5 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAO82943.1 - 0.022 14.6 2.8 0.044 13.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 GAO82943.1 - 0.044 13.4 8.4 0.1 12.2 5.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO82943.1 - 0.07 13.1 10.0 0.13 12.3 6.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.1 GAO82943.1 - 0.076 13.3 0.7 0.076 13.3 0.5 2.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING-like PF08746.6 GAO82943.1 - 0.27 11.2 6.1 0.66 10.0 4.2 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 GAO82943.1 - 1.8 8.4 7.7 3.5 7.5 4.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Bestrophin PF01062.16 GAO82944.1 - 4e-40 137.6 0.0 8.5e-40 136.5 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FAD_binding_2 PF00890.19 GAO82945.1 - 8.6e-93 311.4 0.0 9.9e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO82945.1 - 1e-06 28.6 0.1 4.6e-06 26.5 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAO82945.1 - 4.3e-06 26.0 0.1 8.3e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAO82945.1 - 7.6e-06 25.0 0.8 0.00012 21.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO82945.1 - 1.9e-05 23.8 0.4 4.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 GAO82945.1 - 2.4e-05 24.5 0.1 7.2e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO82945.1 - 3.3e-05 23.8 0.0 0.0014 18.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO82945.1 - 0.0022 16.9 0.1 0.0022 16.9 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO82945.1 - 0.0041 16.0 0.2 0.007 15.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAO82945.1 - 0.0054 15.2 2.7 0.0055 15.2 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 GAO82945.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO82945.1 - 0.054 13.9 0.2 2.5 8.5 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO82945.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAO82945.1 - 0.1 11.9 0.0 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 GAO82945.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Vps16_N PF04841.8 GAO82947.1 - 5e-98 328.3 0.0 7.4e-98 327.7 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 GAO82947.1 - 7.9e-80 268.1 0.1 1.3e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Alb1 PF09135.6 GAO82948.1 - 5e-30 104.3 13.7 5e-30 104.3 9.5 1.6 2 0 0 2 2 2 1 Alb1 UCH PF00443.24 GAO82949.1 - 3.2e-36 124.8 0.0 5e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO82949.1 - 1.1e-06 28.3 0.0 6.4e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.1 GAO82950.1 - 0.00064 19.3 0.0 11 6.2 0.0 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 GAO82950.1 - 0.015 15.4 0.0 0.43 10.7 0.0 2.7 1 1 2 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.1 GAO82950.1 - 0.043 13.4 0.0 3 7.5 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair RuvA_C PF07499.8 GAO82950.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain PUL PF08324.6 GAO82951.1 - 2.8e-43 147.6 0.1 3.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 GAO82951.1 - 2.1e-40 137.9 0.0 3.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 GAO82951.1 - 1.5e-16 59.9 0.0 2.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 GAO82951.1 - 0.00015 21.5 0.1 0.00037 20.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 GAO82951.1 - 0.00018 21.6 0.1 0.00093 19.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 GAO82951.1 - 0.0078 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Redoxin PF08534.5 GAO82951.1 - 0.015 14.8 0.1 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 GAO82951.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.16 GAO82951.1 - 0.03 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family AAA_12 PF13087.1 GAO82953.1 - 9.4e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DBR1 PF05011.8 GAO82953.1 - 0.029 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain YbjQ_1 PF01906.12 GAO82954.1 - 4.5e-32 110.6 0.2 5.1e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding PAN_4 PF14295.1 GAO82954.1 - 0.086 12.5 0.3 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 PAN domain Zn_clus PF00172.13 GAO82955.1 - 0.0025 17.6 0.8 0.0055 16.5 0.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4239 PF14023.1 GAO82955.1 - 0.22 10.8 1.3 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) FUSC PF04632.7 GAO82955.1 - 0.5 8.7 7.5 0.027 12.9 1.7 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Zn_clus PF00172.13 GAO82956.1 - 0.0036 17.1 4.9 0.0061 16.4 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Y_phosphatase3 PF13350.1 GAO82957.1 - 7.7e-36 123.8 0.0 9.5e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAO82957.1 - 9.3e-08 32.0 0.1 3.2e-06 27.1 0.0 2.8 3 0 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 GAO82957.1 - 0.0051 16.1 0.0 0.02 14.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family BTB PF00651.26 GAO82958.1 - 5.1e-13 48.9 0.0 6.9e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PhyH PF05721.8 GAO82958.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3754 PF12576.3 GAO82961.1 - 0.57 9.8 4.6 0.29 10.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) NLPC_P60 PF00877.14 GAO82962.1 - 1.2e-19 70.0 0.0 2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.6 GAO82962.1 - 9.2e-07 28.9 0.1 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_5 PF05382.8 GAO82962.1 - 0.0018 17.8 0.2 0.0046 16.5 0.1 1.7 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.6 GAO82962.1 - 0.0032 16.8 0.0 0.58 9.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Serglycin PF04360.7 GAO82962.1 - 0.84 9.3 8.2 1.4 8.6 5.7 1.5 1 1 0 1 1 1 0 Serglycin GRP PF07172.6 GAO82962.1 - 8.4 6.9 14.8 14 6.2 10.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family Caleosin PF05042.8 GAO82964.1 - 1.9e-52 177.3 0.0 3.1e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Caleosin related protein PP2C PF00481.16 GAO82964.1 - 3.1e-36 125.0 0.0 4.5e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C EF-hand_1 PF00036.27 GAO82964.1 - 1.5e-06 27.0 1.9 1.7e-05 23.7 0.3 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAO82964.1 - 0.00027 20.5 1.8 0.0031 17.2 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 GAO82964.1 - 0.00063 19.8 1.1 0.0048 17.0 0.7 2.4 1 1 0 1 1 1 1 EF-hand domain pair PP2C_2 PF13672.1 GAO82964.1 - 0.00093 18.6 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C EF-hand_5 PF13202.1 GAO82964.1 - 0.024 13.9 3.0 0.047 13.0 0.2 2.7 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 GAO82964.1 - 0.088 12.4 0.7 0.43 10.2 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair Urease_gamma PF00547.13 GAO82966.1 - 2.8e-23 81.7 0.0 9.9e-23 80.0 0.0 1.8 1 1 0 1 1 1 1 Urease, gamma subunit Ferritin_2 PF13668.1 GAO82967.1 - 1.9e-20 73.2 0.0 2.8e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain NRDE-2 PF08424.5 GAO82967.1 - 0.15 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference FMN_bind_2 PF04299.7 GAO82968.1 - 5.5e-55 185.4 0.0 1e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.3 GAO82968.1 - 9.6e-48 162.6 1.3 1.2e-47 162.3 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 GAO82969.1 - 3.6e-58 196.6 0.0 9.6e-58 195.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAO82969.1 - 0.0024 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO82969.1 - 0.016 14.2 0.0 0.38 9.7 0.0 2.6 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAO82969.1 - 0.031 13.0 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Ricin_B_lectin PF00652.17 GAO82970.1 - 4.9e-16 58.8 1.7 8.4e-16 58.1 1.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.13 GAO82970.1 - 2.6e-14 52.7 0.0 1.2e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Melibiase NUDIX PF00293.23 GAO82971.1 - 1.3e-24 86.3 0.4 1.7e-24 86.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 GAO82971.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain OPT PF03169.10 GAO82972.1 - 2.2e-165 551.6 51.4 2.5e-165 551.4 35.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RRM_1 PF00076.17 GAO82973.1 - 4.1e-16 58.3 0.0 6.5e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO82973.1 - 1.4e-12 47.4 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAO82973.1 - 1.1e-05 25.7 0.8 1.1e-05 25.7 0.6 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 GAO82973.1 - 1.9e-05 24.4 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CbiG_mid PF11761.3 GAO82973.1 - 0.051 13.8 0.1 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Cobalamin biosynthesis central region HSP33 PF01430.14 GAO82973.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein Shadoo PF14999.1 GAO82973.1 - 0.97 9.2 9.7 3.4 7.5 6.2 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Snf7 PF03357.16 GAO82974.1 - 6.6e-23 80.9 13.6 6.6e-23 80.9 9.4 2.0 1 1 1 2 2 2 1 Snf7 DUF1704 PF08014.6 GAO82974.1 - 0.019 13.9 1.1 0.032 13.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Gon7 PF08738.5 GAO82974.1 - 0.02 14.8 2.4 0.3 11.1 0.7 2.4 2 0 0 2 2 2 0 Gon7 family MerR-DNA-bind PF09278.6 GAO82974.1 - 0.12 12.8 16.9 0.55 10.6 0.1 4.4 5 0 0 5 5 5 0 MerR, DNA binding DUF826 PF05696.6 GAO82974.1 - 0.33 11.1 6.5 0.097 12.8 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Atg14 PF10186.4 GAO82974.1 - 1.3 7.9 18.3 0.037 12.9 7.1 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cytochrom_B562 PF07361.6 GAO82974.1 - 2.1 8.7 9.6 2.8 8.3 0.5 2.8 1 1 1 2 2 2 0 Cytochrome b562 GAS PF13851.1 GAO82974.1 - 2.9 7.0 11.1 0.055 12.6 2.1 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4404 PF14357.1 GAO82974.1 - 7.2 7.1 15.6 2.5 8.5 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CS PF04969.11 GAO82975.1 - 2.2e-09 37.7 0.3 3.8e-09 36.9 0.2 1.4 1 1 0 1 1 1 1 CS domain zf-CCCH PF00642.19 GAO82976.1 - 1.8e-05 24.3 1.4 1.8e-05 24.3 1.0 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 GAO82976.1 - 0.066 12.8 0.3 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DAO PF01266.19 GAO82977.1 - 2.9e-22 79.0 0.1 3.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO82977.1 - 0.017 13.9 0.0 0.034 12.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 GAO82977.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAO82977.1 - 0.019 15.0 0.0 0.45 10.6 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 GAO82977.1 - 0.05 13.6 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO82977.1 - 0.051 13.6 0.0 0.068 13.2 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 GAO82978.1 - 0.068 13.0 3.0 0.085 12.7 0.1 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Hamartin PF04388.7 GAO82979.1 - 1.7 7.2 4.8 2.7 6.5 3.3 1.2 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_16 PF00722.16 GAO82980.1 - 1e-11 44.4 0.1 1.5e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 adh_short PF00106.20 GAO82981.1 - 1.8e-20 73.5 0.3 2.5e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82981.1 - 4e-10 39.6 0.1 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO82981.1 - 2.4e-09 37.3 0.0 2.9e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.8 GAO82981.1 - 8.9e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF460) DUF1776 PF08643.5 GAO82981.1 - 0.00084 18.5 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 GAO82981.1 - 0.04 14.3 0.2 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 GAO82981.1 - 0.043 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-HIT PF04438.11 GAO82982.1 - 2.4e-10 39.8 9.9 3.9e-10 39.1 6.9 1.4 1 0 0 1 1 1 1 HIT zinc finger WEMBL PF05701.6 GAO82983.1 - 1e-05 24.2 0.5 1.4e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 GAO82983.1 - 1.3e-05 24.5 13.6 0.00049 19.3 2.0 1.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Atg14 PF10186.4 GAO82983.1 - 0.00092 18.2 1.6 0.00092 18.2 1.1 2.0 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 GAO82983.1 - 0.0022 16.6 1.7 0.0036 16.0 1.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 GAO82983.1 - 0.0026 16.3 1.0 0.008 14.6 0.7 1.7 1 1 0 1 1 1 1 AAA domain ATG16 PF08614.6 GAO82983.1 - 0.0028 17.5 4.1 0.0028 17.5 2.9 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) ADIP PF11559.3 GAO82983.1 - 0.0056 16.5 2.5 0.019 14.9 1.7 1.9 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 GAO82983.1 - 0.007 14.1 1.1 0.011 13.5 0.8 1.2 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 GAO82983.1 - 0.0074 16.1 3.9 0.012 15.4 0.2 2.6 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 GAO82983.1 - 0.0074 16.0 5.3 0.39 10.5 0.2 3.2 1 1 4 5 5 5 2 Lipoprotein leucine-zipper COG5 PF10392.4 GAO82983.1 - 0.014 15.3 3.0 0.37 10.7 0.2 3.2 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Laminin_I PF06008.9 GAO82983.1 - 0.018 14.3 0.4 0.038 13.2 0.2 1.5 1 1 0 1 1 1 0 Laminin Domain I MscS_porin PF12795.2 GAO82983.1 - 0.018 14.3 3.1 0.073 12.3 0.8 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 GAO82983.1 - 0.02 14.7 2.2 1.3 8.7 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 GAO82983.1 - 0.023 14.0 1.4 0.046 13.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4618 PF15397.1 GAO82983.1 - 0.038 13.3 2.6 5.4 6.2 0.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) HALZ PF02183.13 GAO82983.1 - 0.041 13.6 0.5 2.2 8.0 0.1 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 GAO82983.1 - 0.049 13.6 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 GAO82983.1 - 0.058 12.9 0.6 0.21 11.1 0.4 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 GAO82983.1 - 0.071 13.4 0.4 1.1 9.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 GAO82983.1 - 0.085 12.7 0.1 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Cob_adeno_trans PF01923.13 GAO82983.1 - 0.11 12.2 1.5 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Baculo_PEP_C PF04513.7 GAO82983.1 - 0.45 10.3 6.5 0.11 12.2 1.7 2.0 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cast PF10174.4 GAO82983.1 - 0.48 8.3 10.3 0.011 13.8 2.4 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.7 GAO82983.1 - 1.4 9.1 6.4 9.4 6.5 3.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 GAO82983.1 - 1.6 8.3 5.9 6 6.4 1.8 2.2 1 1 1 2 2 2 0 IncA protein DUF1319 PF07028.6 GAO82983.1 - 3.1 7.9 6.9 17 5.6 2.2 3.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1319) FlxA PF14282.1 GAO82983.1 - 7.5 6.5 10.2 0.092 12.6 0.5 2.6 3 0 0 3 3 3 0 FlxA-like protein Peptidase_C48 PF02902.14 GAO82985.1 - 4.5e-25 88.5 0.0 7.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.16 GAO82985.1 - 5.1e-17 61.7 1.7 1.4e-16 60.3 1.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 GAO82986.1 - 2.9e-49 166.5 0.0 3.6e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO82986.1 - 1.3e-12 48.2 0.0 1.9e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO82986.1 - 2.8e-05 23.4 0.0 6.9e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAO82986.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAO82986.1 - 0.029 13.4 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.5 GAO82987.1 - 3.1e-17 61.9 0.7 4.1e-17 61.6 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glyco_hydro_43 PF04616.9 GAO82991.1 - 7.9e-11 41.5 7.2 2.4e-09 36.7 2.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 MFS_1 PF07690.11 GAO82993.1 - 4.2e-45 153.9 37.9 4.2e-45 153.9 26.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO82993.1 - 2.4e-11 42.9 29.8 1.4e-10 40.3 20.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAO82993.1 - 1.1e-06 27.2 3.9 1.7e-06 26.5 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAO82993.1 - 9.4e-05 20.6 7.7 0.037 12.1 0.3 3.6 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_6 PF12697.2 GAO82994.1 - 1.1e-19 71.1 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO82994.1 - 6e-13 48.7 0.0 9.1e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO82994.1 - 8.5e-12 45.1 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 GAO82994.1 - 7.6e-06 25.7 0.0 0.00065 19.4 0.0 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 GAO82994.1 - 4.8e-05 23.0 0.0 0.00016 21.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO82994.1 - 0.0024 17.1 0.0 0.21 10.7 0.0 2.3 1 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 GAO82994.1 - 0.0026 17.2 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 GAO82994.1 - 0.048 13.8 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Glyoxalase PF00903.20 GAO82995.1 - 4.7e-13 49.2 0.0 8.6e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO82995.1 - 6.6e-11 42.7 0.1 7.5e-10 39.3 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAO82995.1 - 5.3e-07 29.6 0.0 7.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.1 GAO82996.1 - 7.6e-43 147.0 0.1 9.1e-43 146.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO82996.1 - 1.2e-28 100.1 2.4 1.5e-28 99.8 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO82996.1 - 4.2e-12 46.1 0.5 6.9e-12 45.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO82996.1 - 5.3e-05 22.7 0.3 0.00049 19.6 0.3 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO82996.1 - 0.00045 19.9 1.7 0.001 18.8 1.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 GAO82996.1 - 0.0075 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 GAO82996.1 - 0.048 12.7 0.3 0.082 11.9 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 GAO82996.1 - 0.26 10.5 1.4 15 4.7 0.8 2.1 2 0 0 2 2 2 0 NmrA-like family Fungal_trans PF04082.13 GAO82997.1 - 6.4e-14 51.4 0.9 1.2e-13 50.5 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO82997.1 - 3.1e-07 30.1 28.9 9e-06 25.5 9.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 GAO82999.1 - 7.2e-62 209.1 0.0 7.2e-62 209.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO82999.1 - 6.8e-56 189.9 0.0 1.1e-55 189.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAO82999.1 - 5.6e-53 180.0 0.0 8.7e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAO82999.1 - 7.4e-51 172.3 0.1 1.9e-50 171.0 0.1 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO82999.1 - 1.2e-38 132.6 0.5 4.2e-38 130.8 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO82999.1 - 2.2e-34 117.8 0.3 5.4e-34 116.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAO82999.1 - 1.1e-16 60.6 0.1 3.6e-16 58.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO82999.1 - 1.7e-09 38.6 0.0 7.2e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO82999.1 - 1e-07 31.6 1.1 3.3e-07 30.0 0.0 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAO82999.1 - 0.00013 21.0 6.0 0.00016 20.7 0.4 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 GAO82999.1 - 0.00024 21.5 0.0 0.00065 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO82999.1 - 0.00077 19.0 0.1 0.0025 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAO82999.1 - 0.019 15.1 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAO82999.1 - 0.31 9.7 0.2 0.89 8.2 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family HsbA PF12296.3 GAO83000.1 - 1.1e-21 77.0 0.6 2.1e-21 76.0 0.4 1.5 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HsbA PF12296.3 GAO83001.1 - 1.5e-27 95.8 0.5 2.2e-27 95.3 0.3 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Methyltransf_11 PF08241.7 GAO83002.1 - 7.7e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83002.1 - 3.8e-13 49.4 0.0 6.1e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83002.1 - 1.2e-09 38.7 0.0 2.4e-09 37.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83002.1 - 1.2e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83002.1 - 1.8e-09 37.8 0.0 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83002.1 - 6.7e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83002.1 - 1.2e-06 28.9 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAO83002.1 - 0.00022 20.4 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAO83002.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 GAO83002.1 - 0.042 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 GAO83002.1 - 0.057 12.7 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Abhydrolase_3 PF07859.8 GAO83003.1 - 3.1e-53 180.5 0.2 3.9e-53 180.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO83003.1 - 1.9e-05 24.4 0.0 7.6e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 GAO83003.1 - 3.8e-05 22.5 0.0 6.8e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAO83003.1 - 6.2e-05 22.3 0.0 0.00068 18.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 GAO83003.1 - 0.014 14.6 0.1 0.031 13.5 0.1 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2823 PF11034.3 GAO83004.1 - 8.8e-32 109.0 12.5 9.6e-32 108.9 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) RapA_C PF12137.3 GAO83004.1 - 0.17 10.7 2.6 0.18 10.6 1.8 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Zn_clus PF00172.13 GAO83006.1 - 0.0013 18.5 16.6 0.0013 18.5 11.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 GAO83006.1 - 0.0062 16.8 6.7 0.0062 16.8 4.6 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type ISAV_HA PF06215.6 GAO83006.1 - 0.16 10.2 0.6 0.23 9.7 0.4 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Glyco_hydro_18 PF00704.23 GAO83008.1 - 6.2e-73 246.2 4.7 1e-72 245.5 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MU117 PF15474.1 GAO83008.1 - 5.8e-15 55.5 9.3 5.8e-15 55.5 6.4 3.4 4 0 0 4 4 4 1 Meiotically up-regulated gene family Chitin_bind_1 PF00187.14 GAO83008.1 - 3.6e-11 42.8 17.7 3.6e-11 42.8 12.3 6.2 5 1 0 5 5 5 2 Chitin recognition protein LysM PF01476.15 GAO83009.1 - 3.2e-21 74.9 0.3 0.00016 21.5 0.0 4.6 4 0 0 4 4 4 4 LysM domain Aspzincin_M35 PF14521.1 GAO83009.1 - 1.4e-06 28.8 0.3 2.2e-05 24.9 0.0 2.8 2 1 1 3 3 3 1 Lysine-specific metallo-endopeptidase Mucin PF01456.12 GAO83009.1 - 0.00044 20.0 57.1 0.015 15.0 10.7 3.6 3 0 0 3 3 3 3 Mucin-like glycoprotein Translin PF01997.11 GAO83009.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Translin family Ank_2 PF12796.2 GAO83010.1 - 2.6e-17 62.9 0.0 0.00025 21.3 0.0 2.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO83010.1 - 9.5e-11 40.8 0.1 0.0059 16.7 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 GAO83010.1 - 2.2e-10 39.7 0.0 0.012 15.3 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 GAO83010.1 - 3.4e-09 36.6 0.0 0.04 14.1 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO83010.1 - 6.5e-06 26.5 0.0 0.026 15.0 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Peptidase_A4 PF01828.12 GAO83011.1 - 9e-72 240.4 9.1 1e-71 240.2 6.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family Glyco_hydro_18 PF00704.23 GAO83013.1 - 5.1e-77 259.6 0.4 7.3e-77 259.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAO83013.1 - 2.9e-08 33.5 6.9 2.9e-08 33.5 4.8 4.3 5 0 0 5 5 5 1 Chitin recognition protein Pectate_lyase_3 PF12708.2 GAO83014.1 - 4.6e-82 275.4 12.7 1e-65 222.0 4.0 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.15 GAO83014.1 - 2.9e-07 30.2 0.0 1.8e-05 24.4 0.0 3.4 3 0 0 3 3 3 1 LysM domain End_N_terminal PF12218.3 GAO83014.1 - 0.00014 21.2 3.2 0.081 12.4 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Epimerase PF01370.16 GAO83014.1 - 0.00031 20.2 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2OG-FeII_Oxy_2 PF13532.1 GAO83015.1 - 1.5e-23 83.6 0.0 4.5e-23 82.0 0.0 1.7 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cyt-b5 PF00173.23 GAO83015.1 - 6.7e-20 70.6 0.0 1.7e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain AMP-binding PF00501.23 GAO83016.1 - 2e-81 273.5 0.0 2.6e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO83016.1 - 3.8e-11 43.7 0.0 8.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHO4 PF01384.15 GAO83017.1 - 3.8e-27 94.7 0.2 6e-26 90.8 0.2 2.2 1 1 0 1 1 1 1 Phosphate transporter family Fungal_trans PF04082.13 GAO83017.1 - 1.5e-18 66.6 3.4 1.5e-18 66.6 2.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83017.1 - 2.2e-09 37.0 12.5 5e-09 35.9 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.16 GAO83018.1 - 1.1e-155 518.7 0.0 1.3e-155 518.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 GAO83018.1 - 0.00047 19.6 0.6 0.78 9.1 0.2 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAO83018.1 - 0.0015 18.0 0.0 0.0063 16.0 0.0 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.1 GAO83018.1 - 0.044 14.0 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF1954 PF09199.5 GAO83018.1 - 0.072 13.2 0.3 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1954) Med2 PF11214.3 GAO83018.1 - 0.13 12.2 0.4 0.34 10.9 0.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 adh_short PF00106.20 GAO83019.1 - 2.6e-17 63.2 0.0 4.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83019.1 - 2.9e-11 43.6 0.0 4.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83019.1 - 7.9e-10 38.6 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO83019.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO83019.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF608 PF04685.8 GAO83019.1 - 0.092 11.4 0.0 0.48 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF608 3HCDH_N PF02737.13 GAO83019.1 - 0.16 11.5 0.1 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_FMN PF00724.15 GAO83021.1 - 2.6e-77 260.1 0.0 4.2e-77 259.4 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 GAO83022.1 - 3.6e-28 98.5 1.7 4.5e-28 98.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83022.1 - 2.2e-21 76.7 0.1 2.7e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83022.1 - 9.6e-14 51.4 0.4 1.4e-13 50.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO83022.1 - 5.1e-05 22.8 0.2 7.8e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO83022.1 - 0.0049 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 GAO83022.1 - 0.0055 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family HHH_5 PF14520.1 GAO83022.1 - 0.049 13.8 0.2 0.14 12.3 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix domain ERG4_ERG24 PF01222.12 GAO83023.1 - 1.3e-138 462.1 17.4 1.5e-138 461.9 12.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.13 GAO83024.1 - 2e-18 66.2 0.7 3.3e-18 65.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83024.1 - 3.2e-09 36.5 9.2 5.9e-09 35.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 GAO83024.1 - 0.022 14.9 0.2 0.079 13.2 0.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Bromodomain PF00439.20 GAO83024.1 - 0.095 12.6 0.0 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Bromodomain Glyco_hydro_67M PF07488.7 GAO83025.1 - 5.2e-156 518.5 0.0 7.1e-156 518.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 GAO83025.1 - 3.5e-95 317.7 6.1 5.2e-95 317.1 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 GAO83025.1 - 7.4e-32 109.9 0.0 1.6e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 GAO83025.1 - 0.0061 17.0 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BetaGal_dom4_5 PF13364.1 GAO83025.1 - 0.02 15.1 1.2 0.21 11.8 0.2 2.5 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Zn_clus PF00172.13 GAO83026.1 - 9.2e-11 41.4 8.8 1.9e-10 40.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO83026.1 - 3.4e-10 39.2 0.0 8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 GAO83026.1 - 0.002 18.0 0.0 0.0061 16.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Herpes_UL95 PF03038.9 GAO83026.1 - 0.036 12.9 0.1 0.061 12.1 0.1 1.3 1 0 0 1 1 1 0 UL95 family DUF515 PF04415.7 GAO83027.1 - 9.7 4.3 5.5 13 3.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TPR_10 PF13374.1 GAO83028.1 - 4.4e-83 271.1 14.1 3.1e-12 45.9 0.0 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAO83028.1 - 2.1e-66 219.8 8.7 5.6e-18 64.6 0.0 7.3 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 GAO83028.1 - 2e-18 64.6 24.2 0.0011 18.5 0.0 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat Na_Ca_ex PF01699.19 GAO83028.1 - 4.4e-16 58.7 25.6 8.7e-11 41.5 5.8 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TPR_16 PF13432.1 GAO83028.1 - 8.9e-13 48.5 6.2 0.28 11.9 0.0 7.3 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAO83028.1 - 7.2e-12 44.7 5.1 0.031 13.9 0.0 6.1 4 1 3 7 7 7 5 TPR repeat TPR_1 PF00515.23 GAO83028.1 - 1.5e-11 43.4 9.5 0.27 10.8 0.0 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAO83028.1 - 7.3e-11 41.1 10.2 0.22 11.5 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAO83028.1 - 1.9e-09 37.0 13.8 1.5 9.4 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO83028.1 - 6.7e-09 35.2 11.5 1.8 8.9 0.0 8.4 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83028.1 - 1.6e-08 34.4 12.9 2.9 8.7 0.2 8.9 6 3 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO83028.1 - 2.5e-08 34.1 4.9 2.6 8.4 0.0 6.8 3 3 4 7 7 7 2 Tetratricopeptide repeat Rab5-bind PF09311.6 GAO83028.1 - 4.1e-06 26.8 9.9 1 9.2 0.1 4.9 3 1 2 5 5 5 2 Rabaptin-like protein TPR_8 PF13181.1 GAO83028.1 - 3.6e-05 23.2 14.7 2.4 8.1 0.0 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat PPR PF01535.15 GAO83028.1 - 0.0021 17.8 0.3 26 5.0 0.0 5.4 5 0 0 5 5 5 0 PPR repeat Apc3 PF12895.2 GAO83028.1 - 0.0042 17.1 0.0 0.56 10.3 0.0 3.8 3 1 2 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Osmo_CC PF08946.5 GAO83028.1 - 0.028 14.4 2.5 1.5 8.9 0.0 3.5 4 0 0 4 4 3 0 Osmosensory transporter coiled coil TPR_20 PF14561.1 GAO83028.1 - 0.072 13.2 5.3 13 5.9 0.1 5.0 4 3 1 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAO83028.1 - 0.15 11.8 0.0 9.7 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1897 PF09005.5 GAO83028.1 - 6.2 6.3 7.9 17 4.9 0.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) Cad PF03596.8 GAO83029.1 - 2.2e-22 79.7 4.9 2.2e-22 79.7 3.4 2.0 2 1 1 3 3 3 1 Cadmium resistance transporter Frag1 PF10277.4 GAO83029.1 - 0.02 14.3 0.8 0.02 14.3 0.6 1.6 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family DUF1469 PF07332.6 GAO83029.1 - 1.5 8.5 6.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF4199 PF13858.1 GAO83029.1 - 3.6 7.4 7.8 12 5.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) CDO_I PF05995.7 GAO83030.1 - 3.3e-37 127.3 0.1 4.1e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I 2OG-FeII_Oxy PF03171.15 GAO83032.1 - 2.7e-12 46.8 0.0 5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAO83032.1 - 1.6e-08 35.0 0.0 3.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribonuc_L-PSP PF01042.16 GAO83033.1 - 2.1e-23 82.3 0.0 2.5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 GAO83034.1 - 9.8e-38 129.7 21.2 9.8e-38 129.7 14.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4319 PF14203.1 GAO83034.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) HpcH_HpaI PF03328.9 GAO83035.1 - 1.7e-35 121.8 0.3 2e-35 121.6 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 GAO83035.1 - 0.0019 17.1 0.0 0.1 11.4 0.0 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Fungal_trans PF04082.13 GAO83036.1 - 9.9e-20 70.4 4.1 1.4e-19 69.9 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO83036.1 - 0.00069 19.8 13.8 0.0045 17.2 2.2 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO83036.1 - 0.0083 16.3 21.7 0.073 13.4 2.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO83036.1 - 0.035 14.4 0.2 0.035 14.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAO83036.1 - 0.058 13.3 2.6 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 GAO83037.1 - 3e-29 102.0 0.2 5.6e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83037.1 - 1.6e-16 60.8 0.1 2.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83037.1 - 1.6e-12 47.4 0.1 3.8e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 KR domain TPR_12 PF13424.1 GAO83037.1 - 3.5e-10 39.6 0.2 7.6e-10 38.5 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAO83037.1 - 7.8e-10 38.3 0.9 4.5e-08 32.7 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Epimerase PF01370.16 GAO83037.1 - 4.1e-08 32.9 0.1 7.7e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPR_1 PF00515.23 GAO83037.1 - 4.1e-06 26.1 0.2 7.8e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO83037.1 - 8.9e-06 25.1 0.2 2.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Polysacc_synt_2 PF02719.10 GAO83037.1 - 0.00049 19.0 0.0 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TPR_2 PF07719.12 GAO83037.1 - 0.00051 19.7 0.2 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAO83037.1 - 0.0011 18.5 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 GAO83037.1 - 0.0016 18.0 0.1 0.0041 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83037.1 - 0.0021 18.5 0.1 0.022 15.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat NAD_binding_10 PF13460.1 GAO83037.1 - 0.0041 17.1 1.6 0.056 13.4 0.6 2.8 1 1 1 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAO83037.1 - 0.0092 15.7 0.4 0.087 12.6 0.3 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ACT_7 PF13840.1 GAO83037.1 - 0.045 13.2 0.7 0.51 9.8 0.1 2.5 2 0 0 2 2 2 0 ACT domain RmlD_sub_bind PF04321.12 GAO83037.1 - 0.047 12.5 0.1 0.11 11.3 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 GAO83037.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TPR_16 PF13432.1 GAO83037.1 - 0.073 13.7 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.15 GAO83037.1 - 0.095 12.7 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 1 0 PPR repeat TPR_17 PF13431.1 GAO83037.1 - 0.11 12.6 0.1 0.65 10.3 0.0 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat Lyase_8_N PF08124.6 GAO83039.1 - 0.016 14.1 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain NACHT PF05729.7 GAO83040.1 - 3.9e-07 29.8 0.5 1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAO83040.1 - 0.0027 17.8 0.3 0.067 13.3 0.0 3.4 3 1 2 5 5 5 1 AAA domain DUF765 PF05570.6 GAO83041.1 - 0.16 11.9 9.2 1 9.3 2.4 2.8 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) MFS_1 PF07690.11 GAO83042.1 - 4.1e-46 157.3 45.0 1.1e-45 155.8 30.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83042.1 - 8.1e-17 60.9 36.6 1.2e-13 50.4 11.9 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAO83042.1 - 7.5e-15 54.1 26.6 1.3e-14 53.3 18.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BatD PF13584.1 GAO83042.1 - 0.11 11.1 0.8 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 Oxygen tolerance Beta-lactamase PF00144.19 GAO83043.1 - 1.4e-54 185.3 0.0 1.7e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAO83043.1 - 0.031 13.5 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase YrhK PF14145.1 GAO83044.1 - 0.00016 21.2 19.7 3.9 7.1 4.1 5.1 3 2 0 3 3 3 3 YrhK-like protein PCAF_N PF06466.6 GAO83044.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF1049 PF06305.6 GAO83044.1 - 7.5 6.1 7.6 0.41 10.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Fungal_trans PF04082.13 GAO83045.1 - 2.3e-09 36.5 1.2 4.1e-09 35.6 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83045.1 - 0.0005 19.9 2.1 0.0013 18.6 1.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAO83046.1 - 3e-96 322.7 19.2 3.4e-96 322.5 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83046.1 - 2.3e-41 141.7 30.1 7.7e-34 116.9 11.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 GAO83046.1 - 0.016 14.6 12.0 0.29 10.4 1.3 4.0 4 0 0 4 4 4 0 ABC transporter transmembrane region z-alpha PF02295.12 GAO83046.1 - 0.053 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain DUF4181 PF13789.1 GAO83046.1 - 5.9 6.8 7.0 23 4.9 0.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4181) Glyco_hydro_2_C PF02836.12 GAO83047.1 - 8.1e-104 346.6 0.1 3.9e-103 344.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 GAO83047.1 - 4.8e-61 206.1 0.0 1.3e-60 204.8 0.0 1.7 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 GAO83047.1 - 4.6e-51 172.6 0.3 1.1e-50 171.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain VIT1 PF01988.14 GAO83047.1 - 3.4e-41 141.0 0.0 5.3e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 VIT family Cellulase PF00150.13 GAO83047.1 - 4.7e-13 48.9 0.7 4.7e-13 48.9 0.5 2.6 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2 PF00703.16 GAO83047.1 - 2.9e-12 47.0 0.0 8.7e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ank_2 PF12796.2 GAO83048.1 - 1.2e-36 124.8 1.2 6.5e-14 52.0 0.1 4.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83048.1 - 4.3e-33 111.4 2.9 1.1e-06 28.1 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAO83048.1 - 6.2e-23 80.7 0.2 2e-07 31.3 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO83048.1 - 8.7e-19 67.1 8.3 5.6e-06 26.4 0.0 6.6 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83048.1 - 3.5e-17 60.7 0.2 0.0088 16.1 0.0 7.1 6 1 1 7 7 7 3 Ankyrin repeat PNP_UDP_1 PF01048.15 GAO83048.1 - 5e-07 28.9 0.4 4.3e-06 25.8 0.7 2.2 2 1 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.7 GAO83048.1 - 0.00045 19.9 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAO83048.1 - 0.045 13.7 0.0 0.2 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAO83048.1 - 0.077 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.17 GAO83050.1 - 5.2e-93 312.4 0.0 6.4e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lactamase_B PF00753.22 GAO83051.1 - 6.2e-09 35.7 0.2 1e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO83051.1 - 5.7e-05 22.7 0.1 9.1e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 GAO83052.1 - 1.7e-05 23.8 0.0 3.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83052.1 - 4.7e-05 23.1 6.9 8.5e-05 22.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAO83053.1 - 1.9e-22 79.4 39.4 1.9e-22 79.4 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83053.1 - 0.0083 14.7 28.6 0.0086 14.6 4.2 3.2 2 2 0 3 3 3 2 Sugar (and other) transporter Peptidase_U4 PF03419.8 GAO83053.1 - 0.035 13.1 3.2 0.091 11.8 2.2 1.7 1 0 0 1 1 1 0 Sporulation factor SpoIIGA UL40 PF10682.4 GAO83053.1 - 0.94 8.9 3.2 2.2 7.7 0.5 2.2 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 AA_permease_2 PF13520.1 GAO83054.1 - 9.8e-50 169.3 43.5 1.3e-49 168.8 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO83054.1 - 5e-28 97.6 41.4 1.2e-27 96.3 28.7 1.5 1 1 0 1 1 1 1 Amino acid permease YrhC PF14143.1 GAO83054.1 - 2.9 7.9 5.2 1.5 8.8 0.5 2.8 2 0 0 2 2 2 0 YrhC-like protein ATP_transf PF09830.4 GAO83057.1 - 1.2e-18 66.6 0.0 1.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase CorA PF01544.13 GAO83058.1 - 0.0032 16.5 0.2 0.005 15.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans_2 PF11951.3 GAO83059.1 - 3.1e-07 29.3 0.0 8.9e-07 27.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3557 PF12078.3 GAO83059.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Aldo_ket_red PF00248.16 GAO83060.1 - 4.2e-69 232.5 0.0 4.7e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1115 PF06544.7 GAO83061.1 - 3.3e-21 75.3 0.0 5.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Dabb PF07876.7 GAO83062.1 - 2.2e-10 40.8 0.1 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ATP-grasp_4 PF13535.1 GAO83063.1 - 3.5e-12 46.4 0.0 1.3e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAO83063.1 - 3.4e-10 39.6 0.0 5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAO83063.1 - 3.4e-05 22.7 0.0 0.0045 15.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 GAO83063.1 - 9.9e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAO83063.1 - 0.0038 16.7 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 GAO83063.1 - 0.005 16.1 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.1 GAO83063.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.14 GAO83063.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain P5CR_dimer PF14748.1 GAO83064.1 - 3.1e-37 126.8 2.0 4.9e-37 126.2 0.6 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAO83064.1 - 2.4e-18 66.3 0.4 6.5e-18 64.9 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 GAO83064.1 - 1.6e-05 24.6 5.1 0.00044 20.0 3.5 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 GAO83064.1 - 0.00021 21.1 0.2 0.0015 18.4 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 GAO83064.1 - 0.0012 17.7 0.1 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.15 GAO83064.1 - 0.0052 16.8 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NMT1_2 PF13379.1 GAO83064.1 - 0.019 14.3 0.5 0.18 11.1 0.0 2.4 3 0 0 3 3 3 0 NMT1-like family UDPG_MGDP_dh_C PF03720.10 GAO83064.1 - 0.026 14.6 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Rossmann-like PF10727.4 GAO83064.1 - 0.031 13.9 0.2 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Rossmann-like domain ApbA PF02558.11 GAO83064.1 - 0.032 13.6 0.8 0.062 12.7 0.5 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding PF02629.14 GAO83064.1 - 0.041 14.3 0.5 0.094 13.2 0.3 1.7 1 0 0 1 1 1 0 CoA binding domain ketoacyl-synt PF00109.21 GAO83065.1 - 3e-80 269.3 0.0 4.9e-80 268.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO83065.1 - 1.8e-47 162.2 0.0 2.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO83065.1 - 7.8e-32 109.6 0.1 1.8e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO83065.1 - 1.6e-29 103.7 0.0 2.8e-28 99.6 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAO83065.1 - 2.2e-29 101.4 16.8 5.9e-10 39.2 0.9 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAO83065.1 - 5.2e-07 29.7 2.1 0.00022 21.2 0.0 3.2 2 2 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO83065.1 - 2.4e-06 27.3 0.0 0.093 12.4 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAO83065.1 - 7.2e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RHH_3 PF12651.2 GAO83065.1 - 0.29 10.8 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain MIP-T3 PF10243.4 GAO83065.1 - 3.4 6.0 0.0 5.9 5.2 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zn_clus PF00172.13 GAO83066.1 - 3e-10 39.8 10.5 3e-10 39.8 7.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 GAO83066.1 - 2.9e-08 33.1 0.4 6.1e-08 32.0 0.3 1.6 1 0 0 1 1 1 1 Aflatoxin regulatory protein MFS_1 PF07690.11 GAO83067.1 - 1e-40 139.5 46.9 1.9e-40 138.6 32.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO83067.1 - 1.6e-07 29.9 24.5 3.7e-07 28.7 17.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 GAO83068.1 - 3.4e-16 59.5 5.4 1.4e-12 47.8 3.7 3.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83068.1 - 1.6e-12 47.7 0.1 5.5e-07 29.5 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83068.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAO83068.1 - 0.0044 17.1 0.1 0.0079 16.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 GAO83068.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 GAO83068.1 - 0.014 15.7 0.4 0.03 14.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.8 GAO83068.1 - 0.11 11.8 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family COesterase PF00135.23 GAO83069.1 - 3e-86 290.2 0.0 4.6e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Pyr_redox_3 PF13738.1 GAO83069.1 - 1.9e-20 73.8 0.0 3.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO83069.1 - 1.3e-14 53.3 0.0 2.5e-14 52.3 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO83069.1 - 1.1e-12 47.5 0.2 7.3e-11 41.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO83069.1 - 2.3e-10 40.6 0.0 4.3e-09 36.5 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO83069.1 - 5.1e-08 32.8 0.1 8.3e-07 28.9 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO83069.1 - 1.5e-06 27.3 0.0 2.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO83069.1 - 1.9e-05 23.7 0.1 0.0003 19.7 0.0 2.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO83069.1 - 3e-05 23.1 0.0 6.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAO83069.1 - 0.0003 19.9 0.4 0.0011 18.1 0.0 2.1 3 0 0 3 3 3 1 Thi4 family Abhydrolase_3 PF07859.8 GAO83069.1 - 0.0013 18.3 0.1 0.0052 16.3 0.1 2.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 GAO83069.1 - 0.0014 17.7 0.1 0.011 14.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAO83069.1 - 0.0037 17.0 0.1 0.086 12.6 0.0 3.1 4 0 0 4 4 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAO83069.1 - 0.004 17.3 0.0 0.1 12.8 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox PF00070.22 GAO83069.1 - 0.027 14.8 0.8 3.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAO83069.1 - 0.032 13.3 0.5 1.7 7.7 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 GAO83069.1 - 0.14 10.5 0.2 0.27 9.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 GAO83069.1 - 0.22 11.1 1.6 5 6.7 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 GAO83070.1 - 7.7e-42 143.1 0.0 1e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO83070.1 - 3.5e-05 24.3 0.0 8.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83070.1 - 7.2e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAO83070.1 - 0.0007 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 GAO83070.1 - 0.023 15.1 0.0 0.097 13.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Cu-oxidase_3 PF07732.10 GAO83071.1 - 1.7e-38 130.9 0.4 4.2e-38 129.7 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO83071.1 - 1.6e-28 98.9 11.1 6.3e-22 77.5 0.8 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO83071.1 - 2e-17 63.5 0.0 1.2e-15 57.7 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase MFS_1 PF07690.11 GAO83072.1 - 8.6e-46 156.2 49.7 8.6e-46 156.2 34.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83072.1 - 2.7e-14 52.5 33.2 4.1e-13 48.7 9.9 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAO83072.1 - 2.5e-11 42.5 21.1 6.5e-11 41.1 14.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAO83072.1 - 0.00063 19.4 4.5 0.31 10.8 0.3 2.7 2 0 0 2 2 2 2 MFS_1 like family AhpC-TSA PF00578.16 GAO83073.1 - 1e-31 109.2 0.0 1.4e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAO83073.1 - 1.8e-12 47.0 0.0 2.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAO83073.1 - 1e-08 34.6 0.7 1.9e-08 33.8 0.5 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Response_reg PF00072.19 GAO83074.1 - 2e-21 76.0 0.6 7.8e-21 74.1 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAO83074.1 - 4.5e-18 64.9 0.2 2.4e-17 62.6 0.1 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 GAO83074.1 - 5.6e-11 42.0 0.0 1.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 GAO83074.1 - 1.3e-10 41.5 2.0 2.4e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Pkinase_Tyr PF07714.12 GAO83074.1 - 1.6e-09 37.2 0.0 3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.21 GAO83074.1 - 5.2e-06 26.1 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 GAO83074.1 - 0.0022 17.9 11.8 0.083 12.8 1.3 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAO83074.1 - 0.0088 15.8 5.4 5.2 7.2 0.3 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83074.1 - 0.012 16.2 0.4 0.012 16.2 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2235 PF09994.4 GAO83075.1 - 1.9e-81 273.5 0.0 2.4e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 GAO83075.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Beta-lactamase PF00144.19 GAO83076.1 - 1.7e-68 231.1 0.0 2.1e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Alpha-amylase PF00128.19 GAO83077.1 - 2.3e-22 79.8 0.0 4.6e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Aminotran_1_2 PF00155.16 GAO83080.1 - 4.3e-40 137.7 0.0 5.2e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAO83080.1 - 3.9e-10 38.5 0.0 5.8e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO83080.1 - 1.6e-06 27.0 0.0 2.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO83080.1 - 7.4e-06 25.3 0.0 1.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase CATSPERG PF15064.1 GAO83080.1 - 0.072 10.8 0.1 0.1 10.3 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma DegT_DnrJ_EryC1 PF01041.12 GAO83080.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Acetyltransf_3 PF13302.1 GAO83081.1 - 1.3e-18 67.5 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO83081.1 - 2.5e-12 46.6 0.0 3.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAO83081.1 - 2.2e-10 40.7 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAO83081.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO83081.1 - 0.00019 21.5 0.0 0.00051 20.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO83081.1 - 0.029 14.4 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO83081.1 - 0.04 13.6 0.0 0.089 12.5 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein HAMP PF00672.20 GAO83082.1 - 4.3e-47 158.1 17.0 3.7e-09 36.6 0.1 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 GAO83082.1 - 1.6e-31 108.2 0.1 5.7e-31 106.5 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO83082.1 - 4.9e-27 94.1 1.9 1.1e-24 86.6 0.3 3.4 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 GAO83082.1 - 4.4e-16 58.6 0.1 4.4e-16 58.6 0.1 4.2 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 GAO83082.1 - 0.018 14.8 17.5 1.5 8.6 0.1 6.7 6 3 0 6 6 6 0 Uncharacterized conserved protein (DUF2365) NOD PF06816.8 GAO83082.1 - 0.027 13.5 0.1 0.86 8.7 0.0 2.8 2 0 0 2 2 2 0 NOTCH protein AAA_13 PF13166.1 GAO83082.1 - 0.11 10.9 25.7 0.24 9.8 2.4 4.0 2 1 2 4 4 4 0 AAA domain Pox_A_type_inc PF04508.7 GAO83082.1 - 0.21 11.4 2.3 0.91 9.4 0.6 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IncA PF04156.9 GAO83082.1 - 0.25 10.9 13.1 0.37 10.3 3.3 3.9 4 0 0 4 4 4 0 IncA protein NAAA-beta PF15508.1 GAO83082.1 - 0.28 11.5 3.7 20 5.6 0.1 5.1 5 1 1 6 6 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Scaffolding_pro PF11418.3 GAO83082.1 - 0.99 9.7 11.7 43 4.5 0.0 5.9 5 1 0 5 5 5 0 Phi29 scaffolding protein VBS PF08913.5 GAO83082.1 - 6.9 6.9 14.7 23 5.2 0.3 4.9 3 1 0 4 4 4 0 Vinculin Binding Site Metallophos PF00149.23 GAO83083.1 - 9.7e-09 34.9 1.3 1.9e-08 33.9 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 GAO83083.1 - 0.00084 19.3 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain MFS_1 PF07690.11 GAO83084.1 - 4.4e-27 94.7 38.3 3.3e-18 65.5 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83084.1 - 2.2e-07 29.8 3.4 2.2e-07 29.8 2.4 3.8 3 1 1 4 4 4 2 Sugar (and other) transporter ETRAMP PF09716.5 GAO83084.1 - 0.11 12.4 0.1 0.7 9.8 0.1 2.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MFS_1 PF07690.11 GAO83085.1 - 2.8e-05 23.0 7.1 2.8e-05 23.0 5.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAO83085.1 - 0.00068 19.1 2.6 0.00068 19.1 1.8 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.27 GAO83086.1 - 2.4e-178 572.4 19.0 5.4e-16 57.7 0.0 13.1 13 0 0 13 13 13 12 WD domain, G-beta repeat DUF1652 PF07865.6 GAO83086.1 - 1.1e-11 44.0 0.0 13 5.4 0.0 10.0 6 3 4 10 10 10 0 Protein of unknown function (DUF1652) PD40 PF07676.7 GAO83086.1 - 5e-10 38.8 8.5 29 4.4 0.0 11.2 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 GAO83086.1 - 1.5e-09 36.9 9.0 40 3.6 0.0 10.8 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature NACHT PF05729.7 GAO83086.1 - 1.1e-08 34.9 0.0 2.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 GAO83086.1 - 8.1e-08 32.0 14.3 0.001 18.6 0.2 4.1 1 1 1 3 3 3 3 PQQ-like domain AAA_16 PF13191.1 GAO83086.1 - 5.9e-07 29.6 0.1 2.7e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain TruB_C PF09142.6 GAO83086.1 - 1.1e-06 28.1 2.3 84 2.9 0.0 9.2 12 0 0 12 12 11 0 tRNA Pseudouridine synthase II, C terminal Cytochrom_D1 PF02239.11 GAO83086.1 - 2.7e-05 22.6 0.0 3.6 5.7 0.0 4.6 2 1 3 5 5 5 1 Cytochrome D1 heme domain IKI3 PF04762.7 GAO83086.1 - 2.9e-05 22.1 1.8 0.088 10.6 0.1 3.4 3 0 0 3 3 3 2 IKI3 family PSII_BNR PF14870.1 GAO83086.1 - 5.6e-05 22.2 0.1 5.2 5.9 0.0 4.1 1 1 2 4 4 4 1 Photosynthesis system II assembly factor YCF48 GSDH PF07995.6 GAO83086.1 - 5.6e-05 22.3 0.2 4.3 6.3 0.0 6.1 2 1 3 6 6 6 1 Glucose / Sorbosone dehydrogenase WXG100 PF06013.7 GAO83086.1 - 0.0011 18.9 0.2 1.2e+02 2.7 0.0 6.6 9 0 0 9 9 6 0 Proteins of 100 residues with WXG APS_kinase PF01583.15 GAO83086.1 - 0.0027 17.3 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.17 GAO83086.1 - 0.0085 14.9 0.0 0.023 13.5 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 GAO83086.1 - 0.011 15.9 0.1 0.045 13.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiN PF02553.10 GAO83086.1 - 0.041 13.8 0.0 28 4.7 0.0 5.0 7 0 0 7 7 3 0 Cobalt transport protein component CbiN Arylsulfotran_2 PF14269.1 GAO83086.1 - 0.07 12.2 0.1 0.6 9.2 0.0 2.4 2 1 0 3 3 3 0 Arylsulfotransferase (ASST) AAA_22 PF13401.1 GAO83086.1 - 0.085 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAO83086.1 - 0.09 13.5 0.0 0.48 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Med9 PF07544.8 GAO83086.1 - 0.096 12.4 0.0 26 4.6 0.0 3.4 4 0 0 4 4 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_33 PF13671.1 GAO83086.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO83086.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO83086.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAO83086.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_S8 PF00082.17 GAO83088.1 - 6.4e-41 140.3 0.0 6.4e-40 137.0 0.0 2.3 2 1 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 GAO83088.1 - 6.2e-13 49.1 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 GAO83088.1 - 5.5e-07 29.2 0.0 1.7e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.1 GAO83088.1 - 0.046 13.4 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain adh_short PF00106.20 GAO83089.1 - 4.8e-21 75.4 5.1 1.8e-18 67.0 1.1 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAO83089.1 - 2.9e-12 46.6 0.7 5e-12 45.8 0.5 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO83089.1 - 5.8e-12 45.9 0.4 1.1e-06 28.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO83089.1 - 0.00048 20.1 0.5 0.00092 19.2 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO83089.1 - 0.0012 17.6 0.1 0.0017 17.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 GAO83089.1 - 0.014 15.5 0.1 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TIG PF01833.19 GAO83089.1 - 0.13 12.3 0.7 3.7 7.5 0.0 2.6 1 1 1 2 2 2 0 IPT/TIG domain Sua5_yciO_yrdC PF01300.13 GAO83090.1 - 6.9e-11 41.7 0.0 8.5e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Pyr_redox_2 PF07992.9 GAO83091.1 - 6.3e-13 49.0 0.0 3.6e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO83091.1 - 0.026 13.0 0.0 0.2 10.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAO83091.1 - 0.18 11.8 2.5 3.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRP21_like_P PF12230.3 GAO83092.1 - 0.17 11.3 1.0 0.24 10.8 0.7 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein GST_N PF02798.15 GAO83093.1 - 5.1e-15 55.4 0.0 1.4e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO83093.1 - 5.5e-13 48.9 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO83093.1 - 7.3e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO83093.1 - 2.2e-12 46.8 0.0 4.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO83093.1 - 5.1e-07 30.1 0.0 7.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO83093.1 - 5.1e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAO83093.1 - 0.032 14.6 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain DUF3791 PF12668.2 GAO83093.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Sugar_tr PF00083.19 GAO83094.1 - 2.2e-106 356.1 22.0 2.5e-106 355.9 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83094.1 - 1.1e-21 76.9 39.5 3.2e-16 59.0 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAO83094.1 - 0.0028 15.7 1.1 0.0061 14.6 0.8 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.20 GAO83095.1 - 2.8e-26 92.4 0.4 3.6e-26 92.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83095.1 - 2.7e-25 89.5 0.0 3.6e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83095.1 - 3.3e-14 52.9 0.1 4.9e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Transketolase_N PF00456.16 GAO83096.1 - 6.7e-113 376.8 0.0 1e-112 376.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAO83096.1 - 5.4e-38 130.2 0.0 1.4e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 GAO83096.1 - 6.2e-06 25.3 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 GAO83096.1 - 2.3e-05 23.2 0.0 3.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PepSY_2 PF13670.1 GAO83096.1 - 0.12 12.2 0.1 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Transketolase_C PF02780.15 GAO83096.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans_2 PF11951.3 GAO83097.1 - 4.1e-16 58.5 4.3 7.5e-16 57.7 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_7 PF13499.1 GAO83098.1 - 5.4e-15 55.2 0.5 6.2e-15 55.0 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO83098.1 - 6.1e-15 53.3 1.3 3.6e-07 29.0 0.6 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAO83098.1 - 5.1e-12 44.5 0.2 0.00014 21.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 GAO83098.1 - 9.5e-11 41.1 0.7 1.6e-10 40.4 0.3 1.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 GAO83098.1 - 1.6e-06 27.1 3.1 6.6e-05 22.0 0.5 2.7 3 1 0 3 3 3 1 EF hand DUF1103 PF06513.6 GAO83098.1 - 0.0045 16.4 1.5 0.0058 16.0 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SPARC_Ca_bdg PF10591.4 GAO83098.1 - 0.0055 16.7 0.1 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAO83098.1 - 0.0092 15.6 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PMBR PF09373.5 GAO83098.1 - 0.066 13.1 0.1 10 6.2 0.0 3.0 3 1 0 3 3 3 0 Pseudomurein-binding repeat TerB PF05099.8 GAO83098.1 - 0.12 12.0 0.3 1.1 9.0 0.1 1.9 1 1 1 2 2 2 0 Tellurite resistance protein TerB Glycos_trans_3N PF02885.12 GAO83098.1 - 0.13 11.8 0.3 3 7.5 0.1 2.5 2 1 1 3 3 3 0 Glycosyl transferase family, helical bundle domain MFS_1 PF07690.11 GAO83099.1 - 1.7e-39 135.5 55.2 1.2e-30 106.4 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83099.1 - 2.4e-11 42.9 35.0 2.2e-08 33.1 7.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAO83099.1 - 8.4e-08 31.0 21.1 1.3e-07 30.3 13.5 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 GAO83099.1 - 0.0013 18.4 0.7 0.0013 18.4 0.5 3.5 4 0 0 4 4 4 1 MFS_1 like family Pyridoxal_deC PF00282.14 GAO83100.1 - 3.1e-17 62.0 0.0 1.1e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_3 PF01494.14 GAO83101.1 - 1e-68 232.0 0.0 1.4e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO83101.1 - 5.2e-43 146.5 0.0 8.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain AMP-binding PF00501.23 GAO83102.1 - 2.9e-82 276.3 0.0 5.6e-82 275.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ABC_membrane PF00664.18 GAO83102.1 - 9.2e-79 264.6 35.7 1.4e-41 142.7 11.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO83102.1 - 1.4e-68 229.4 0.2 4.5e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Aminotran_5 PF00266.14 GAO83102.1 - 7.2e-46 156.6 0.0 1.3e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V NAD_binding_4 PF07993.7 GAO83102.1 - 3.4e-45 153.9 0.0 6.6e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAO83102.1 - 4.3e-14 52.5 0.0 1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SMC_N PF02463.14 GAO83102.1 - 3.7e-13 49.2 8.0 1.7e-05 24.1 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO83102.1 - 4.9e-08 33.2 0.3 0.14 12.0 0.1 4.3 3 1 0 3 3 3 1 AAA domain AMP-binding_C PF13193.1 GAO83102.1 - 5.9e-08 33.5 0.0 2e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_16 PF13191.1 GAO83102.1 - 3.4e-07 30.4 2.8 0.0064 16.5 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAO83102.1 - 4.1e-07 29.4 2.5 0.027 13.9 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAO83102.1 - 8e-07 27.9 0.6 0.024 13.2 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAO83102.1 - 7.5e-06 25.2 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 GAO83102.1 - 6.3e-05 22.9 0.0 0.4 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 GAO83102.1 - 0.00011 22.9 0.0 0.48 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain PP-binding PF00550.20 GAO83102.1 - 0.00016 21.8 0.1 0.00048 20.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Zeta_toxin PF06414.7 GAO83102.1 - 0.0002 20.5 0.2 0.88 8.6 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.15 GAO83102.1 - 0.0002 20.1 0.0 0.38 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.1 GAO83102.1 - 0.00026 20.8 0.1 1.6 8.7 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit 3Beta_HSD PF01073.14 GAO83102.1 - 0.00042 19.1 0.0 0.002 16.9 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_30 PF13604.1 GAO83102.1 - 0.00045 19.8 2.1 2.9 7.4 0.0 4.6 4 1 0 4 4 4 1 AAA domain AAA_10 PF12846.2 GAO83102.1 - 0.0012 18.3 3.0 9.3 5.5 0.0 4.5 5 0 0 5 5 5 0 AAA-like domain Cys_Met_Meta_PP PF01053.15 GAO83102.1 - 0.0028 16.0 0.0 0.0085 14.4 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme AAA_22 PF13401.1 GAO83102.1 - 0.0041 17.2 4.1 2.4 8.2 0.1 4.2 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO83102.1 - 0.011 15.1 0.0 5.5 6.4 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 GAO83102.1 - 0.035 14.1 0.0 19 5.2 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 GAO83102.1 - 0.12 12.6 0.3 15 5.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAO83102.1 - 0.14 11.9 0.2 12 5.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAO83102.1 - 0.16 11.3 3.5 1.9 7.8 0.0 3.7 5 0 0 5 5 4 0 AAA domain AAA_18 PF13238.1 GAO83102.1 - 0.22 11.8 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAO83102.1 - 6.5 5.6 0.0 57 2.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP-grasp_4 PF13535.1 GAO83103.1 - 1e-23 84.0 0.0 5.3e-22 78.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAO83103.1 - 1.1e-06 27.6 0.0 0.0035 16.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAO83103.1 - 2.9e-05 23.5 0.0 7.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAO83103.1 - 5.7e-05 23.0 0.0 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 GAO83103.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain CPSase_L_D2 PF02786.12 GAO83103.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Methyltransf_33 PF10017.4 GAO83104.1 - 2.9e-27 95.0 0.0 4.7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DAO PF01266.19 GAO83105.1 - 1.3e-25 90.0 0.0 2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO83105.1 - 0.00067 19.5 0.0 1.6 8.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO83105.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAO83105.1 - 0.025 13.2 0.0 0.046 12.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAO83105.1 - 0.086 12.6 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 GAO83105.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FadA PF09403.5 GAO83107.1 - 0.0002 21.3 3.6 0.0002 21.3 2.5 2.8 2 1 0 2 2 2 1 Adhesion protein FadA His_kinase PF06580.8 GAO83107.1 - 0.051 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase WXG100 PF06013.7 GAO83107.1 - 0.17 11.9 4.7 0.8 9.7 0.4 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF4407 PF14362.1 GAO83107.1 - 6.3 5.6 28.0 0.45 9.4 2.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) 4HBT PF03061.17 GAO83111.1 - 1.4e-10 41.1 0.1 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PS-DH PF14765.1 GAO83111.1 - 0.046 12.8 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase Glyco_hydro_12 PF01670.11 GAO83112.1 - 5.1e-17 62.0 1.2 6.2e-17 61.8 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Lipase_GDSL PF00657.17 GAO83113.1 - 1.7e-10 41.1 0.1 2.8e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Prenyltrans_2 PF13249.1 GAO83114.1 - 2.5e-34 118.0 9.5 3.4e-15 56.4 0.0 5.8 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 GAO83114.1 - 1.1e-28 98.3 12.2 3.3e-08 32.9 0.0 6.6 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 GAO83114.1 - 1.6e-28 98.8 13.5 1.6e-08 34.4 0.4 6.3 4 3 2 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 GAO83114.1 - 7.8e-09 35.1 3.1 0.27 10.3 0.0 6.0 4 1 0 4 4 4 3 Pectic acid lyase A2M_comp PF07678.9 GAO83114.1 - 3.5e-06 26.4 0.6 1.8 7.7 0.0 4.6 5 0 0 5 5 5 3 A-macroglobulin complement component p450 PF00067.17 GAO83115.1 - 2.8e-46 158.0 0.0 3.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.22 GAO83116.1 - 9.8e-18 64.4 0.0 8.5e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO83116.1 - 3.6e-05 23.3 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 GAO83117.1 - 2.8e-13 50.1 0.2 4.3e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83117.1 - 1.7e-05 24.7 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83117.1 - 0.025 14.2 0.6 0.053 13.1 0.4 1.6 1 1 0 1 1 1 0 KR domain Fungal_trans PF04082.13 GAO83118.1 - 2.2e-15 56.2 0.0 3.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transferase PF02458.10 GAO83119.1 - 1.6e-19 69.7 0.0 1.9e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family DEK_C PF08766.6 GAO83120.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain MFS_1 PF07690.11 GAO83121.1 - 6.4e-15 54.7 79.7 3.5e-12 45.7 26.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 GAO83121.1 - 5e-08 33.1 0.1 9.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_2 PF13347.1 GAO83121.1 - 0.048 12.0 24.9 0.016 13.6 10.3 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein Dynamin_N PF00350.18 GAO83122.1 - 8.6e-20 71.2 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAO83122.1 - 3.3e-13 49.0 0.0 7.6e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAO83122.1 - 1.2e-06 28.4 0.0 1.4e-05 24.9 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO83122.1 - 1.5e-05 25.4 0.0 3.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 GAO83122.1 - 0.0011 18.2 0.1 1.5 8.0 0.0 2.8 3 1 0 3 3 3 2 Ferrous iron transport protein B AAA_21 PF13304.1 GAO83122.1 - 0.024 14.5 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAO83122.1 - 0.045 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.8 GAO83124.1 - 1.1e-32 113.1 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.13 GAO83124.1 - 1.3e-11 43.9 0.9 2.6e-11 42.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TrkA_N PF02254.13 GAO83124.1 - 0.2 11.6 0.1 0.71 9.8 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 GAO83125.1 - 3.6e-13 49.7 0.0 6.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO83125.1 - 3.1e-06 26.9 0.0 5.1e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO83125.1 - 0.00029 20.6 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 GAO83125.1 - 0.0035 16.3 0.1 0.0084 15.0 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAO83125.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 GAO83126.1 - 6.2e-49 164.2 4.6 3e-18 65.9 0.1 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83126.1 - 5.8e-47 155.2 16.3 4.8e-07 29.2 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 GAO83126.1 - 5.3e-30 102.7 11.9 0.00026 21.1 0.0 7.8 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO83126.1 - 3e-28 97.6 5.5 3.5e-07 30.5 0.0 7.8 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83126.1 - 1.5e-22 77.4 4.7 0.0053 16.8 0.0 10.2 11 0 0 11 11 11 5 Ankyrin repeat NACHT PF05729.7 GAO83126.1 - 1.5e-10 40.9 0.0 2.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAO83126.1 - 1.3e-06 28.5 0.0 1.3e-06 28.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 GAO83126.1 - 7.8e-06 26.0 0.0 3.1e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 GAO83126.1 - 0.011 14.7 0.2 0.19 10.6 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 GAO83126.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 GAO83126.1 - 0.018 15.2 0.0 0.084 13.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 GAO83126.1 - 0.048 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase GIT1_C PF12205.3 GAO83126.1 - 0.06 13.1 0.1 13 5.6 0.1 2.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_11 PF13086.1 GAO83126.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb5_N PF03871.9 GAO83126.1 - 0.2 12.0 3.8 10 6.6 0.0 5.0 5 1 1 6 6 6 0 RNA polymerase Rpb5, N-terminal domain MACPF PF01823.14 GAO83127.1 - 2.2e-05 24.2 0.4 0.0014 18.3 0.1 2.8 2 0 0 2 2 2 2 MAC/Perforin domain Ank_4 PF13637.1 GAO83128.1 - 0.064 13.8 0.3 0.7 10.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF1908 PF08926.6 GAO83128.1 - 0.066 11.9 0.1 0.097 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Glyco_hydro_25 PF01183.15 GAO83129.1 - 1.6e-27 96.5 0.0 2.9e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 25 Sugar_tr PF00083.19 GAO83130.1 - 1.1e-83 281.3 31.8 8.8e-72 242.0 13.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO83130.1 - 7.9e-25 87.3 30.3 1.3e-24 86.6 16.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO83130.1 - 0.018 14.8 6.8 0.61 9.9 0.0 4.0 4 0 0 4 4 4 0 MFS_1 like family Bac_rhamnosid PF05592.6 GAO83131.1 - 1e-171 571.6 0.0 1.3e-171 571.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAO83131.1 - 2.6e-52 176.8 0.0 4.1e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Alpha-L-AF_C PF06964.7 GAO83132.1 - 6.5e-33 113.9 1.5 1.6e-32 112.7 1.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus AMP-binding PF00501.23 GAO83133.1 - 1.6e-65 221.1 0.0 2.9e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 GAO83133.1 - 2.2e-14 52.9 0.7 3.6e-14 52.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.1 GAO83133.1 - 0.032 15.1 0.0 0.072 14.0 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Mannitol_dh_C PF08125.8 GAO83134.1 - 8.7e-75 251.0 0.0 1.3e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAO83134.1 - 3.6e-44 150.3 0.0 5.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Methyltransf_11 PF08241.7 GAO83135.1 - 2.3e-13 50.4 0.0 4.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83135.1 - 3.7e-09 36.3 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83135.1 - 1.8e-08 34.9 0.0 3.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83135.1 - 6.4e-08 32.4 0.0 1.7e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83135.1 - 1.6e-07 31.6 0.0 2.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83135.1 - 1.9e-05 24.9 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83135.1 - 0.00027 20.9 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO83135.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FmrO PF07091.6 GAO83135.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 GAO83135.1 - 0.051 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 GAO83135.1 - 0.075 11.9 0.0 0.97 8.3 0.0 2.0 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family SUFU PF05076.8 GAO83135.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) Glyoxalase_2 PF12681.2 GAO83135.1 - 0.29 11.7 1.8 5.6 7.6 0.6 2.7 2 1 0 2 2 1 0 Glyoxalase-like domain DUF1772 PF08592.6 GAO83136.1 - 1.1e-26 93.2 3.5 1.4e-26 92.9 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Cu-oxidase_3 PF07732.10 GAO83137.1 - 1.3e-40 137.8 4.4 1.3e-39 134.6 1.2 3.4 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO83137.1 - 2.5e-36 124.1 12.1 4.9e-35 120.0 1.8 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO83137.1 - 7.1e-33 113.7 0.0 3e-32 111.7 0.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase EthD PF07110.6 GAO83137.1 - 4.3e-20 72.4 1.8 9.6e-20 71.3 1.2 1.6 1 0 0 1 1 1 1 EthD domain DUF4243 PF14027.1 GAO83138.1 - 2.5e-82 276.9 0.0 3.2e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Ubie_methyltran PF01209.13 GAO83139.1 - 1.6e-14 53.6 0.0 2.7e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAO83139.1 - 1e-13 51.5 0.0 2.3e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83139.1 - 2.1e-12 46.9 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83139.1 - 4.3e-10 39.9 0.0 6.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83139.1 - 2.1e-09 37.6 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83139.1 - 2.9e-07 30.3 0.0 4.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83139.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83139.1 - 4.9e-05 23.8 0.0 7.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAO83139.1 - 0.0032 17.1 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO83139.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.13 GAO83139.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Pkinase_Tyr PF07714.12 GAO83139.1 - 0.02 13.9 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase NAD_binding_10 PF13460.1 GAO83140.1 - 1.9e-18 67.0 0.0 2.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO83140.1 - 1.3e-06 27.8 0.0 2.5e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 GAO83140.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO83140.1 - 0.003 16.5 0.0 0.0053 15.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAO83140.1 - 0.0043 15.7 0.0 0.0064 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 GAO83140.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 GAO83140.1 - 0.04 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAO83140.1 - 0.061 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GST_N_3 PF13417.1 GAO83141.1 - 3.5e-12 46.3 0.1 5.7e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO83141.1 - 2e-11 43.6 0.1 4.2e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO83141.1 - 4.4e-11 42.6 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO83141.1 - 1.3e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO83141.1 - 5.1e-06 26.2 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO83141.1 - 2e-05 24.9 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ketoacyl-synt PF00109.21 GAO83142.1 - 2.9e-69 233.3 0.0 6.5e-69 232.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO83142.1 - 1.3e-46 159.4 0.1 7.3e-46 156.9 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO83142.1 - 2.6e-32 111.1 1.4 6.8e-32 109.8 0.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AflR PF08493.5 GAO83142.1 - 1.2e-13 50.7 0.1 2.9e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Aflatoxin regulatory protein PP-binding PF00550.20 GAO83142.1 - 1.5e-07 31.5 0.1 5.4e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Zn_clus PF00172.13 GAO83142.1 - 1e-06 28.5 10.6 1e-06 28.5 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.18 GAO83142.1 - 8.8e-05 21.6 0.1 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.13 GAO83143.1 - 1.3e-28 99.8 0.0 2.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Lactamase_B PF00753.22 GAO83143.1 - 1e-23 83.9 0.3 2.2e-23 82.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO83143.1 - 1.2e-05 24.9 0.1 2.3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_18 PF12847.2 GAO83143.1 - 0.00057 20.4 0.0 0.0022 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RPA_C PF08784.6 GAO83143.1 - 0.0023 18.2 0.0 0.0084 16.5 0.0 1.9 1 0 0 1 1 1 1 Replication protein A C terminal Methyltransf_23 PF13489.1 GAO83143.1 - 0.022 14.4 0.0 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAO83143.1 - 0.091 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Fungal_trans PF04082.13 GAO83144.1 - 3.5e-16 58.8 0.1 4.9e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83144.1 - 7.8e-07 28.9 8.5 1.6e-06 27.9 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0075 PF03702.9 GAO83145.1 - 3.2e-85 286.2 0.0 3.7e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Sugar_tr PF00083.19 GAO83146.1 - 4.4e-85 285.9 17.1 5.7e-85 285.5 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83146.1 - 4.5e-36 124.3 36.0 1.5e-29 102.7 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO83146.1 - 4.6e-07 28.4 5.5 6e-05 21.4 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAO83146.1 - 0.002 17.9 0.1 0.85 9.4 0.0 2.7 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 GAO83146.1 - 0.6 8.0 4.9 16 3.3 3.4 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_4 PF01565.18 GAO83147.1 - 9.2e-32 109.4 5.6 2e-31 108.2 3.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO83147.1 - 1.7e-07 31.0 0.2 3.6e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Iron_permease PF04120.7 GAO83148.1 - 3.1e-42 143.2 9.8 6.7e-28 96.9 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease RseC_MucC PF04246.7 GAO83148.1 - 10 5.7 8.7 1.5 8.3 0.1 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PfkB PF00294.19 GAO83149.1 - 6.8e-43 146.9 2.7 8.7e-43 146.5 1.9 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sugar_tr PF00083.19 GAO83150.1 - 1.5e-103 346.8 35.5 1.9e-103 346.4 24.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83150.1 - 3.3e-19 68.8 61.4 1.2e-11 43.8 20.0 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAO83150.1 - 1.5e-07 31.1 12.3 2.5e-07 30.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_30 PF13556.1 GAO83150.1 - 0.028 13.9 0.2 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Fungal_trans_2 PF11951.3 GAO83151.1 - 3e-15 55.7 0.6 4.6e-15 55.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL PF00657.17 GAO83152.1 - 2e-12 47.4 0.0 1.2e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAO83152.1 - 5.2e-05 23.4 2.6 0.00073 19.7 1.8 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3405 PF11885.3 GAO83153.1 - 1.7e-170 567.5 0.6 2.5e-170 566.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Orn_Arg_deC_N PF02784.11 GAO83154.1 - 1.7e-61 207.6 0.0 2.1e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAO83154.1 - 4.9e-16 58.4 0.0 8.3e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Hepar_II_III PF07940.8 GAO83155.1 - 0.0027 17.5 1.6 0.023 14.5 0.6 2.3 2 0 0 2 2 2 1 Heparinase II/III-like protein Methyltransf_2 PF00891.13 GAO83156.1 - 4.7e-15 55.4 0.0 6.1e-15 55.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO83156.1 - 5e-05 23.0 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 GAO83157.1 - 1e-19 70.4 41.6 1.6e-19 69.8 28.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily WAK_assoc PF14380.1 GAO83158.1 - 9.7 6.7 9.7 11 6.6 0.0 2.8 2 1 0 2 2 2 0 Wall-associated receptor kinase C-terminal DUF3112 PF11309.3 GAO83159.1 - 2e-53 180.4 13.1 4.5e-51 172.8 2.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4184 PF13803.1 GAO83159.1 - 1.2 8.3 11.3 1.1 8.4 1.9 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4184) Syndecan PF01034.15 GAO83159.1 - 1.8 8.2 4.3 0.94 9.1 0.4 2.5 2 0 0 2 2 2 0 Syndecan domain DUF1980 PF09323.5 GAO83159.1 - 1.9 8.2 5.0 2 8.1 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Tmemb_170 PF10190.4 GAO83159.1 - 3.4 7.7 12.1 0.075 13.0 2.1 2.6 2 1 0 2 2 2 0 Putative transmembrane protein 170 CENP-F_C_Rb_bdg PF10490.4 GAO83166.1 - 0.058 12.7 0.5 4.2 6.7 0.1 2.3 1 1 1 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.2 GAO83168.1 - 7.1e-06 26.2 0.0 3.4e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83168.1 - 9e-05 22.0 1.7 6.1 6.8 0.1 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAO83168.1 - 0.00024 21.4 0.6 0.095 13.2 0.0 3.1 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83168.1 - 0.00027 20.8 0.7 6.1 7.4 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 GAO83168.1 - 0.13 12.5 0.2 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO83170.1 - 9.8e-98 320.6 2.9 2.2e-19 69.5 0.0 5.2 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83170.1 - 7.3e-65 211.7 4.1 4.8e-09 35.5 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 GAO83170.1 - 9.4e-48 159.1 6.4 2.3e-08 33.9 0.0 8.2 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO83170.1 - 2.2e-46 155.4 0.3 2.8e-10 40.4 0.0 7.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83170.1 - 2.3e-43 141.8 1.6 9.7e-06 25.3 0.0 9.1 9 1 0 9 9 9 8 Ankyrin repeat F-box-like PF12937.2 GAO83170.1 - 0.0013 18.4 0.6 0.0023 17.5 0.4 1.4 1 0 0 1 1 1 1 F-box-like HeLo PF14479.1 GAO83171.1 - 9.6e-45 152.9 0.0 2.2e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_11 PF13414.1 GAO83171.1 - 3.9e-20 71.2 5.8 1.4e-14 53.5 1.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAO83171.1 - 1.3e-11 43.4 6.0 3.1e-05 23.5 0.3 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO83171.1 - 8.8e-11 40.9 7.4 8.9e-05 21.9 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83171.1 - 1.9e-05 25.1 6.9 0.02 15.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO83171.1 - 3.4e-05 23.3 1.5 0.33 10.8 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO83171.1 - 0.0002 21.2 4.1 0.18 11.7 0.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO83171.1 - 0.00066 19.6 0.3 0.56 10.5 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO83171.1 - 0.0011 18.6 5.3 0.019 14.7 0.1 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83171.1 - 0.0022 18.4 9.9 0.0038 17.7 0.2 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO83171.1 - 0.08 13.2 9.4 0.38 11.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO83171.1 - 2.2 8.9 4.9 59 4.4 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NmrA PF05368.8 GAO83172.1 - 3.9e-24 85.2 0.0 4.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO83172.1 - 8.8e-13 48.6 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO83172.1 - 7.8e-07 28.4 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAO83172.1 - 0.00017 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAO83172.1 - 0.0026 17.2 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO83172.1 - 0.0065 15.4 0.0 0.014 14.3 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein DUF3213 PF11491.3 GAO83172.1 - 0.0098 15.7 0.0 0.044 13.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3213) Shikimate_DH PF01488.15 GAO83172.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAO83172.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 GAO83172.1 - 0.12 11.1 0.0 0.26 10.1 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_trans_1_2 PF13524.1 GAO83172.1 - 0.13 12.5 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 bZIP_1 PF00170.16 GAO83173.1 - 0.00095 19.0 2.0 0.0016 18.3 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor FAD_binding_3 PF01494.14 GAO83175.1 - 3.4e-25 88.8 0.0 1e-24 87.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO83175.1 - 1.8e-05 24.6 0.0 4.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO83175.1 - 0.00019 20.4 0.1 0.0013 17.7 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO83175.1 - 0.011 14.6 0.3 0.2 10.5 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 GAO83175.1 - 0.012 16.0 0.0 0.043 14.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO83175.1 - 0.032 13.0 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAO83175.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO83175.1 - 0.047 13.4 0.1 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAO83175.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAGAT PF03982.8 GAO83176.1 - 6.3e-62 208.9 0.0 9.6e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UDPGT PF00201.13 GAO83176.1 - 1.1e-11 44.0 0.0 1.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAO83176.1 - 0.038 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain p450 PF00067.17 GAO83177.1 - 1e-61 208.8 0.0 1.3e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 GAO83178.1 - 7.9e-85 284.6 26.3 2.6e-44 151.7 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO83178.1 - 5.1e-70 234.0 0.0 5e-34 117.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO83178.1 - 4.5e-15 56.3 0.8 0.0007 19.6 0.2 4.7 3 2 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAO83178.1 - 5e-14 52.0 4.3 0.00021 20.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAO83178.1 - 5.3e-10 38.6 0.6 0.00044 19.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAO83178.1 - 3e-08 32.9 0.0 0.019 14.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAO83178.1 - 6e-08 32.8 3.4 0.00087 19.3 0.2 3.8 3 2 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 GAO83178.1 - 8.6e-08 31.1 2.0 0.012 14.2 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 GAO83178.1 - 9e-08 32.9 0.0 0.0053 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO83178.1 - 3.6e-06 27.1 0.3 0.15 12.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO83178.1 - 6.6e-06 25.6 2.9 0.24 10.7 0.0 4.2 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 GAO83178.1 - 7.9e-05 22.9 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 GAO83178.1 - 0.00014 22.2 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAO83178.1 - 0.00016 21.5 0.0 0.84 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAO83178.1 - 0.00021 21.1 2.8 0.19 11.6 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 GAO83178.1 - 0.00023 20.8 2.4 0.82 9.2 0.0 4.0 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 GAO83178.1 - 0.001 18.8 0.1 1.7 8.3 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 GAO83178.1 - 0.0014 18.4 0.2 0.79 9.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_15 PF13175.1 GAO83178.1 - 0.0014 17.7 0.0 0.035 13.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 GAO83178.1 - 0.0019 17.8 0.3 2.5 7.7 0.0 3.2 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_19 PF13245.1 GAO83178.1 - 0.003 17.2 0.9 4.7 7.0 0.0 3.3 3 0 0 3 3 2 0 Part of AAA domain Mg_chelatase PF01078.16 GAO83178.1 - 0.0053 15.9 0.1 2.1 7.4 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO83178.1 - 0.0061 16.2 0.2 4.2 7.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 GAO83178.1 - 0.0083 14.8 0.0 0.62 8.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.1 GAO83178.1 - 0.012 15.5 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAO83178.1 - 0.015 15.2 1.8 2.4 8.1 0.3 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 GAO83178.1 - 0.015 14.7 5.0 1.7 8.0 0.2 4.0 4 0 0 4 4 4 0 AAA-like domain Zeta_toxin PF06414.7 GAO83178.1 - 0.062 12.3 0.3 3.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 GAO83178.1 - 0.083 12.7 0.0 13 5.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.17 GAO83178.1 - 0.12 11.2 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 GAO83178.1 - 0.13 12.4 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 GAO83178.1 - 0.2 11.4 0.9 19 5.0 0.0 3.4 3 0 0 3 3 3 0 Dynamin family Cutinase PF01083.17 GAO83179.1 - 6.1e-55 185.7 0.3 7e-55 185.5 0.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 GAO83179.1 - 0.00035 20.3 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 GAO83179.1 - 0.0012 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 GAO83179.1 - 0.076 12.3 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ank_2 PF12796.2 GAO83181.1 - 2e-45 153.0 2.1 1.4e-10 41.3 0.0 8.0 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO83181.1 - 1.8e-35 120.6 12.6 3.3e-06 27.4 0.0 11.3 5 3 7 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.25 GAO83181.1 - 2.2e-33 112.4 4.4 0.00034 20.2 0.0 12.0 11 1 0 11 11 11 5 Ankyrin repeat Ank_3 PF13606.1 GAO83181.1 - 1.4e-31 105.3 14.8 0.00097 19.1 0.0 12.7 14 0 0 14 14 13 6 Ankyrin repeat Ank_5 PF13857.1 GAO83181.1 - 3.2e-28 97.1 9.4 7.4e-07 29.2 0.0 9.2 6 3 2 8 8 8 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAO83181.1 - 5.4e-10 38.6 0.2 1.2e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO83181.1 - 5.7e-10 39.0 0.0 3.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 GAO83181.1 - 1.7e-05 24.9 0.0 0.0095 16.0 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.1 GAO83181.1 - 4.7e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO83181.1 - 6.3e-05 23.0 0.0 0.0003 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAO83181.1 - 0.0027 18.5 0.0 0.013 16.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAO83181.1 - 0.0044 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 GAO83181.1 - 0.0068 15.3 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 GAO83181.1 - 0.012 15.0 0.0 0.058 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO83181.1 - 0.038 14.3 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 GAO83181.1 - 0.059 13.1 0.0 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain APS_kinase PF01583.15 GAO83181.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 GAO83181.1 - 0.13 11.2 0.1 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.1 GAO83181.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 GAO83181.1 - 0.16 10.9 0.0 0.51 9.3 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 GAO83181.1 - 0.2 10.3 0.0 0.46 9.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 GAO83181.1 - 0.21 10.5 0.0 0.48 9.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BCAS3 PF12490.3 GAO83181.1 - 0.34 10.1 0.0 0.55 9.4 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 SIR2_2 PF13289.1 GAO83182.1 - 1.9e-15 57.0 0.0 2.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 SIR2-like domain DUF2890 PF11081.3 GAO83184.1 - 2.4 8.1 8.0 2.9 7.9 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GST_C_3 PF14497.1 GAO83186.1 - 1e-10 41.9 0.0 1.4e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO83186.1 - 4.5e-09 36.1 0.0 6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO83186.1 - 1.8e-05 24.5 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 GAO83187.1 - 8.6e-39 133.3 0.0 1.3e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAO83187.1 - 5.9e-16 58.1 0.1 1.1e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 GAO83187.1 - 6.4e-09 34.9 0.0 2.5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO83187.1 - 1e-07 31.1 0.2 5.6e-07 28.7 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO83187.1 - 2.3e-07 29.9 0.0 6.6e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 GAO83187.1 - 2.1e-06 27.5 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO83187.1 - 3.5e-06 27.0 0.1 1.3e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Spherulin4 PF12138.3 GAO83188.1 - 7.2e-63 212.3 0.0 8e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Acetyltransf_7 PF13508.1 GAO83188.1 - 0.065 13.4 0.0 4.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Spherulin4 PF12138.3 GAO83189.1 - 1.1e-62 211.7 0.4 1.3e-62 211.5 0.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF4149 PF13664.1 GAO83189.1 - 0.036 14.1 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF1510 PF07423.6 GAO83189.1 - 0.21 10.9 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3827 PF12877.2 GAO83189.1 - 0.42 8.6 1.9 0.64 8.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Glycos_transf_1 PF00534.15 GAO83190.1 - 7.2e-13 48.3 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 GAO83190.1 - 0.00044 19.8 0.0 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 GAO83190.1 - 0.0017 18.5 0.1 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 MtaB PF12176.3 GAO83190.1 - 0.031 12.6 0.0 0.05 12.0 0.0 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Glyco_trans_1_2 PF13524.1 GAO83190.1 - 0.047 13.9 0.1 0.8 10.0 0.0 2.9 2 1 0 2 2 2 0 Glycosyl transferases group 1 Y_phosphatase3 PF13350.1 GAO83191.1 - 1.1e-28 100.6 0.0 1.5e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAO83191.1 - 2.2e-09 37.2 0.1 5.7e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 GAO83191.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate PP_kinase_C PF13090.1 GAO83191.1 - 0.05 12.1 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain HATPase_c_3 PF13589.1 GAO83192.1 - 3.5e-05 23.4 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 GAO83192.1 - 0.00083 19.0 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF641 PF04859.7 GAO83193.1 - 0.0003 20.5 3.7 0.00099 18.8 1.6 2.4 2 1 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF3584 PF12128.3 GAO83193.1 - 0.0052 14.2 7.7 0.0073 13.7 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) rRNA_methylase PF06962.7 GAO83193.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase CENP-O PF09496.5 GAO83193.1 - 0.13 12.5 1.0 4.4 7.6 0.0 3.6 3 2 1 4 4 4 0 Cenp-O kinetochore centromere component DUF4618 PF15397.1 GAO83193.1 - 0.15 11.3 9.1 2.1 7.5 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF3552 PF12072.3 GAO83193.1 - 0.17 11.0 8.6 0.87 8.7 6.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.1 GAO83193.1 - 0.27 11.1 9.8 0.12 12.2 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 GAO83193.1 - 0.61 9.6 4.1 1.5 8.3 2.9 1.6 1 0 0 1 1 1 0 IncA protein Syntaxin PF00804.20 GAO83193.1 - 6 7.0 9.5 26 5.0 3.8 2.9 1 1 2 3 3 3 0 Syntaxin HSP70 PF00012.15 GAO83194.1 - 3.2e-11 41.8 0.0 4.5e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO83194.1 - 3.8e-08 32.3 0.0 0.0017 16.9 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Zn_clus PF00172.13 GAO83195.1 - 2e-06 27.5 6.9 3.3e-06 26.8 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 GAO83195.1 - 0.017 14.8 3.5 0.62 9.7 0.4 2.5 2 0 0 2 2 2 0 Serglycin MFS_1 PF07690.11 GAO83197.1 - 6.7e-40 136.8 43.5 6.7e-40 136.8 30.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO83197.1 - 5.3e-19 67.8 16.9 6e-19 67.6 11.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.1 GAO83200.1 - 3.9e-26 92.3 0.6 1.3e-18 67.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO83200.1 - 2.1e-20 73.3 0.7 1.8e-18 66.9 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO83200.1 - 1.1e-06 28.4 0.8 4.9e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAO83200.1 - 0.003 17.0 0.1 0.03 13.7 0.1 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_C PF03720.10 GAO83200.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain THF_DHG_CYH_C PF02882.14 GAO83200.1 - 0.092 11.8 0.1 0.73 8.8 0.0 2.3 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 GAO83200.1 - 0.1 12.3 0.6 0.32 10.7 0.4 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pro-kuma_activ PF09286.6 GAO83201.1 - 7.8e-33 113.5 0.0 1.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAO83201.1 - 4e-08 32.7 0.1 7.7e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 GAO83202.1 - 1.2e-45 153.7 0.0 1.6e-13 50.7 0.0 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83202.1 - 2e-37 125.1 0.0 5.7e-08 32.1 0.0 9.2 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAO83202.1 - 8.5e-34 115.3 0.0 3.6e-08 33.7 0.0 7.8 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO83202.1 - 1.5e-33 113.9 0.0 3.1e-09 36.7 0.0 7.3 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83202.1 - 6.4e-29 97.1 0.0 0.0003 20.7 0.0 9.4 10 0 0 10 10 10 5 Ankyrin repeat MFS_1 PF07690.11 GAO83203.1 - 5e-32 110.9 34.0 6.2e-32 110.6 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_11 PF08241.7 GAO83204.1 - 4.3e-22 78.4 0.0 8.3e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83204.1 - 3.1e-17 62.7 0.0 8e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83204.1 - 4e-15 55.7 0.0 2.6e-08 33.6 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83204.1 - 1.4e-13 51.0 0.1 4e-08 33.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83204.1 - 1.2e-11 45.2 0.0 5.5e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83204.1 - 3.1e-11 43.6 0.0 3.4e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.13 GAO83204.1 - 1.7e-09 37.1 0.0 0.00014 21.0 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO83204.1 - 3.9e-07 30.1 0.0 6.7e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 GAO83204.1 - 7.4e-07 28.7 0.0 0.004 16.5 0.0 2.3 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.15 GAO83204.1 - 1.6e-06 27.4 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAO83204.1 - 0.00092 18.6 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAO83204.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 GAO83204.1 - 0.0019 17.5 0.2 2.5 7.3 0.0 3.3 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain UPF0146 PF03686.8 GAO83204.1 - 0.0022 17.8 0.0 0.007 16.1 0.0 1.8 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0146) Methyltransf_9 PF08003.6 GAO83204.1 - 0.0023 16.6 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.13 GAO83204.1 - 0.0024 17.0 0.0 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase TPMT PF05724.6 GAO83204.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 GAO83204.1 - 0.023 14.1 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) FmrO PF07091.6 GAO83204.1 - 0.028 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 GAO83204.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 GAO83204.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 GAO83205.1 - 1.1e-28 100.0 0.0 1.3e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DJ-1_PfpI PF01965.19 GAO83205.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Methyltransf_2 PF00891.13 GAO83206.1 - 2.7e-31 108.6 0.0 3.3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO83206.1 - 0.00043 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HTH_40 PF14493.1 GAO83206.1 - 0.0053 16.9 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Methyltransf_18 PF12847.2 GAO83206.1 - 0.0095 16.5 0.0 0.023 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83206.1 - 0.047 14.1 0.0 0.99 9.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83206.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 GAO83206.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sgf11 PF08209.6 GAO83209.1 - 0.057 12.7 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Aminotran_5 PF00266.14 GAO83210.1 - 2e-18 66.3 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAO83210.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Gln-synt_C PF00120.19 GAO83211.1 - 2.6e-33 115.2 0.0 4.6e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Methyltransf_18 PF12847.2 GAO83212.1 - 5.2e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO83212.1 - 1.6e-09 38.0 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83212.1 - 2.1e-09 37.2 0.0 5.8e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83212.1 - 6.7e-07 29.5 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83212.1 - 1.3e-06 28.7 0.0 2.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPR_10 PF13374.1 GAO83212.1 - 0.0021 17.9 0.1 0.0068 16.3 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_26 PF13659.1 GAO83212.1 - 0.0026 17.7 0.0 0.0096 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO83212.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 GAO83212.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 GAO83212.1 - 0.084 11.9 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 GAO83213.1 - 8.7e-44 149.7 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 GAO83214.1 - 2.3e-15 56.6 0.0 5.5e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO83214.1 - 1.7e-09 37.9 0.0 7.9e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO83214.1 - 3.9e-09 35.6 0.0 6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO83214.1 - 8.2e-05 21.6 0.0 0.00064 18.7 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO83214.1 - 0.0035 16.2 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAO83214.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF3328 PF11807.3 GAO83215.1 - 5.1e-33 114.5 0.0 1.5e-32 113.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) ECH PF00378.15 GAO83215.1 - 4.3e-28 98.0 0.0 7.1e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ESR1_C PF12743.2 GAO83215.1 - 0.045 13.3 1.7 0.068 12.7 0.2 1.9 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal ApbA_C PF08546.6 GAO83216.1 - 2.9e-30 104.8 0.0 6.6e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAO83216.1 - 1.2e-24 86.4 0.0 1.7e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 GAO83216.1 - 0.048 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 GAO83217.1 - 5.6e-13 48.7 1.4 7.9e-13 48.2 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO83217.1 - 1.3e-10 41.4 0.9 1.5e-10 41.1 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO83217.1 - 4.4e-07 29.9 0.2 6.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO83217.1 - 1.1e-05 25.3 1.0 1.5e-05 24.8 0.3 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAO83217.1 - 0.0072 15.9 0.1 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 GAO83217.1 - 0.013 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO83217.1 - 0.013 15.3 0.2 0.042 13.7 0.0 1.8 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAO83217.1 - 0.043 13.5 0.1 0.089 12.5 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein DUF3597 PF12200.3 GAO83218.1 - 9.2e-20 71.3 0.3 9.2e-20 71.3 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3597) PNP_UDP_1 PF01048.15 GAO83218.1 - 1.5e-06 27.3 0.0 5.7e-06 25.4 0.0 2.0 2 1 0 2 2 2 1 Phosphorylase superfamily PARP PF00644.15 GAO83219.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 GAO83219.1 - 1.6e-06 27.6 0.0 3.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO83219.1 - 0.0076 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic E2 family B GST_C PF00043.20 GAO83220.1 - 2.1e-09 37.2 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO83220.1 - 1.1e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO83220.1 - 0.011 16.2 0.1 0.013 15.9 0.1 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3328 PF11807.3 GAO83221.1 - 4e-43 147.6 0.4 4.7e-43 147.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Toxin_13 PF07822.6 GAO83222.1 - 8.2e-11 41.6 15.0 0.28 11.1 0.0 6.1 1 1 5 6 6 6 6 Neurotoxin B-IV-like protein GDNF PF02351.11 GAO83222.1 - 0.013 16.0 5.9 1.3 9.5 4.1 2.6 1 1 0 1 1 1 0 GDNF/GAS1 domain TMEM206 PF15122.1 GAO83222.1 - 0.27 10.1 4.7 16 4.2 0.1 2.9 1 1 2 3 3 3 0 TMEM206 protein family Amidase PF01425.16 GAO83224.1 - 9.3e-37 126.9 1.2 1.7e-36 126.0 0.8 1.3 1 0 0 1 1 1 1 Amidase CRAL_TRIO PF00650.15 GAO83225.1 - 5.3e-46 156.0 0.0 9.2e-46 155.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO83225.1 - 5e-14 52.1 0.0 1.8e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAO83225.1 - 1.3e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_28 PF00295.12 GAO83226.1 - 1.8e-114 382.0 18.0 2.2e-114 381.8 12.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAO83226.1 - 0.0022 17.7 26.8 0.0044 16.7 16.4 2.6 1 1 1 2 2 2 1 Right handed beta helix region DUF2180 PF09947.4 GAO83226.1 - 0.06 13.0 0.5 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) MFS_1 PF07690.11 GAO83227.1 - 5.2e-34 117.5 33.5 5.2e-34 117.5 23.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily CbiK PF06180.6 GAO83228.1 - 0.11 11.5 0.1 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) UPF0004 PF00919.15 GAO83228.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 MFS_1 PF07690.11 GAO83229.1 - 4.5e-36 124.2 29.6 4.5e-36 124.2 20.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily D-ser_dehydrat PF14031.1 GAO83230.1 - 2.4e-23 82.1 0.0 4.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAO83230.1 - 3.4e-14 52.9 0.1 6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Methyltransf_16 PF10294.4 GAO83231.1 - 4.1e-13 49.1 0.0 5.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 GAO83231.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ank_2 PF12796.2 GAO83232.1 - 1.1e-12 48.1 0.0 2.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83232.1 - 1.2e-11 43.8 0.3 1.4e-06 27.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 GAO83232.1 - 1e-08 34.5 0.0 0.0014 18.6 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.1 GAO83232.1 - 6e-08 33.0 0.0 1.3e-06 28.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO83232.1 - 1.9e-07 31.0 0.2 0.0005 20.2 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 GAO83232.1 - 2.4e-06 27.2 0.1 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FAD_binding_3 PF01494.14 GAO83232.1 - 2.6e-06 26.7 0.1 6.9e-05 22.0 0.0 2.7 2 1 0 2 2 2 1 FAD binding domain AAA_22 PF13401.1 GAO83232.1 - 2.3e-05 24.5 0.1 9.4e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain NAD_binding_8 PF13450.1 GAO83232.1 - 8.6e-05 22.4 0.0 0.00036 20.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO83232.1 - 0.00017 20.5 0.4 0.0004 19.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO83232.1 - 0.00036 20.3 0.0 0.03 14.1 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding AAA_16 PF13191.1 GAO83232.1 - 0.00064 19.7 0.5 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain DALR_1 PF05746.10 GAO83232.1 - 0.024 14.6 0.2 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 DALR anticodon binding domain Trp_halogenase PF04820.9 GAO83232.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase zf-RanBP PF00641.13 GAO83232.1 - 0.14 11.2 4.3 0.1 11.7 0.8 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others TauD PF02668.11 GAO83234.1 - 1.8e-34 119.5 0.2 2.9e-34 118.9 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAO83234.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 GAO83235.1 - 7.1e-40 136.7 29.3 1.2e-39 136.0 20.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83235.1 - 4.6e-10 38.6 11.5 4.6e-10 38.6 7.9 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAO83235.1 - 6.1e-07 28.0 6.8 2.8e-06 25.8 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 GAO83235.1 - 4.3 5.7 21.7 0.018 13.5 6.9 2.5 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAO83236.1 - 1.2e-32 113.0 58.9 1.2e-30 106.5 40.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83236.1 - 0.00016 20.4 22.4 0.00016 20.4 15.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter PRANC PF09372.5 GAO83238.1 - 0.0097 15.8 1.1 0.14 12.1 0.1 2.2 1 1 1 2 2 2 1 PRANC domain F-box PF00646.28 GAO83238.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 GAO83238.1 - 0.054 13.2 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 F-box-like DZR PF12773.2 GAO83238.1 - 0.12 12.2 2.8 0.29 10.9 2.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 GAO83238.1 - 0.14 12.1 1.7 1.7 8.6 1.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Podoplanin PF05808.6 GAO83239.1 - 0.0065 16.0 3.1 0.013 15.0 2.2 1.5 1 0 0 1 1 1 1 Podoplanin Phage_GPO PF05929.6 GAO83240.1 - 0.033 13.4 5.4 0.025 13.8 2.6 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COG5 PF10392.4 GAO83240.1 - 0.055 13.4 6.8 0.066 13.1 0.7 2.7 1 1 2 3 3 3 0 Golgi transport complex subunit 5 HSP9_HSP12 PF04119.7 GAO83240.1 - 0.25 11.4 1.1 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 Heat shock protein 9/12 BLOC1_2 PF10046.4 GAO83240.1 - 0.33 11.0 6.0 2.4 8.3 4.0 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 GAO83240.1 - 0.61 9.6 12.8 4 6.9 8.9 2.3 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 GAO83240.1 - 0.68 7.7 7.1 0.49 8.1 3.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 GAO83240.1 - 2.2 8.0 10.8 2.3 8.0 1.6 3.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.2 GAO83241.1 - 2.4e-66 220.1 4.5 1.9e-19 69.7 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83241.1 - 2.7e-62 203.6 23.7 5.3e-10 38.5 0.1 11.6 11 1 1 12 12 11 9 Ankyrin repeat Ank_5 PF13857.1 GAO83241.1 - 4.5e-51 169.7 17.4 3.5e-10 39.7 0.0 9.0 4 2 6 10 10 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO83241.1 - 2.8e-50 167.8 10.9 1.3e-10 41.5 0.0 7.5 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83241.1 - 1.8e-45 148.4 12.1 5.3e-05 23.0 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat BNR_2 PF13088.1 GAO83241.1 - 3.5e-34 118.3 0.3 5.5e-34 117.7 0.2 1.3 1 0 0 1 1 1 1 BNR repeat-like domain NACHT PF05729.7 GAO83241.1 - 3.4e-11 43.0 0.0 6.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain BNR_3 PF13859.1 GAO83241.1 - 8.3e-08 31.6 0.0 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain AAA_22 PF13401.1 GAO83241.1 - 0.00053 20.1 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAO83241.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO83241.1 - 0.0088 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 GAO83241.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HTH_IclR PF09339.5 GAO83241.1 - 0.014 15.0 0.1 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain AAA_5 PF07728.9 GAO83241.1 - 0.031 13.9 0.0 0.096 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAO83241.1 - 0.051 12.7 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAO83241.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAO83241.1 - 0.28 10.7 0.1 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Tyrosinase PF00264.15 GAO83242.1 - 6.3e-48 163.8 0.1 7.9e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_3 PF00933.16 GAO83243.1 - 1.8e-45 155.2 0.0 2.1e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Thioredoxin_2 PF13098.1 GAO83243.1 - 0.032 14.4 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Sua5_yciO_yrdC PF01300.13 GAO83244.1 - 2.1e-12 46.6 0.0 4e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Telomere recombination Peptidase_M35 PF02102.10 GAO83245.1 - 2e-195 648.4 17.0 2.3e-195 648.2 11.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAO83245.1 - 6.6e-07 29.9 2.0 1.1e-06 29.2 0.9 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 GAO83245.1 - 1.6e-05 24.4 1.3 4.9e-05 22.8 0.9 1.6 1 1 0 1 1 1 1 Putative peptidase family CARDB PF07705.6 GAO83245.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 CARDB Hormone_2 PF00123.15 GAO83246.1 - 0.099 12.4 0.9 0.6 10.0 0.3 2.1 2 0 0 2 2 2 0 Peptide hormone DUF2638 PF10937.3 GAO83246.1 - 0.11 13.5 0.5 0.13 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) DUF2370 PF10176.4 GAO83247.1 - 7.2e-86 287.3 0.0 1.6e-85 286.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 GAO83247.1 - 0.49 9.9 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Pkinase PF00069.20 GAO83248.1 - 1e-70 237.8 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83248.1 - 1.3e-30 106.3 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO83248.1 - 0.067 12.9 0.1 0.067 12.9 0.1 2.3 2 2 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 GAO83248.1 - 0.069 12.2 0.1 0.21 10.6 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF604 PF04646.7 GAO83249.1 - 2.7e-11 43.1 0.0 5.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 GAO83249.1 - 1e-06 28.1 0.1 2.4e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Fringe-like tRNA-synt_2b PF00587.20 GAO83250.1 - 9.4e-45 152.2 0.0 1.7e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAO83250.1 - 3.3e-17 62.2 0.3 9.5e-17 60.7 0.2 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 GAO83250.1 - 4.7e-14 51.9 0.0 9.6e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 GAO83250.1 - 0.0007 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 GAO83251.1 - 7.3e-43 145.6 0.1 1.3e-42 144.9 0.0 1.4 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 GAO83252.1 - 5.8e-11 42.5 3.5 5.8e-11 42.5 2.5 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WSC PF01822.14 GAO83253.1 - 1.5e-14 53.6 7.0 1.5e-14 53.6 4.8 2.0 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 GAO83253.1 - 4.7e-10 38.6 0.4 1.3e-09 37.1 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2627 PF11118.3 GAO83253.1 - 0.0068 16.4 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) MFS_1 PF07690.11 GAO83254.1 - 8.1e-47 159.6 27.6 8.1e-47 159.6 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily G_glu_transpept PF01019.16 GAO83257.1 - 2.5e-148 494.7 0.0 2.9e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPMT PF05724.6 GAO83258.1 - 5.5e-26 91.3 0.0 9.7e-26 90.5 0.0 1.3 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 GAO83258.1 - 8.4e-08 32.5 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83258.1 - 1.1e-06 28.3 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83258.1 - 2.5e-06 28.0 0.0 4.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83258.1 - 3.6e-06 26.9 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83258.1 - 1e-05 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83258.1 - 7.2e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAO83258.1 - 0.0085 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 GAO83258.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.14 GAO83259.1 - 1.2e-17 64.6 1.6 8.3e-17 61.8 0.1 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAO83259.1 - 1.1e-06 28.2 0.0 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain Med3 PF11593.3 GAO83259.1 - 0.0077 15.5 2.6 0.012 14.9 1.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Cep57_MT_bd PF06657.8 GAO83259.1 - 0.061 13.2 3.0 0.15 11.9 2.1 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3275 PF11679.3 GAO83259.1 - 0.67 9.5 10.9 0.52 9.9 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Rib_recp_KP_reg PF05104.7 GAO83259.1 - 1.8 9.0 17.8 4.7 7.7 12.3 1.7 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF2890 PF11081.3 GAO83259.1 - 3.8 7.5 12.9 6.3 6.8 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Trehalase PF01204.13 GAO83260.1 - 7.1e-195 648.4 0.4 9.1e-195 648.1 0.3 1.1 1 0 0 1 1 1 1 Trehalase TrkH PF02386.11 GAO83260.1 - 2.7e-76 256.4 2.0 2.7e-76 256.4 1.4 1.5 2 0 0 2 2 2 1 Cation transport protein adh_short PF00106.20 GAO83260.1 - 1.4e-25 90.1 0.0 2.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83260.1 - 1.4e-21 77.3 0.0 2.4e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Trehalase_Ca-bi PF07492.6 GAO83260.1 - 2.1e-17 62.1 0.1 3.9e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain KR PF08659.5 GAO83260.1 - 3e-07 30.2 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO83261.1 - 2.2e-10 40.7 0.1 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ICL PF00463.16 GAO83262.1 - 8.6e-291 964.6 3.4 9.7e-291 964.4 2.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAO83262.1 - 4.3e-13 49.0 0.1 3.2e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 GAO83262.1 - 0.088 12.6 0.2 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 Pre-toxin TG Aldedh PF00171.17 GAO83263.1 - 5.4e-78 262.3 0.0 6.5e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.16 GAO83264.1 - 6.1e-53 179.5 0.0 9.3e-52 175.7 0.0 2.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAO83264.1 - 0.012 15.3 0.1 0.012 15.3 0.1 1.5 2 0 0 2 2 2 0 Clathrin adaptor complex small chain CMV_1a PF12467.3 GAO83264.1 - 0.17 12.2 4.2 0.27 11.5 2.9 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Rrn6 PF10214.4 GAO83264.1 - 1.6 6.7 7.4 2.1 6.3 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pol_alpha_B_N PF08418.5 GAO83264.1 - 1.7 8.1 9.8 2.7 7.4 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SNF2_N PF00176.18 GAO83266.1 - 2.9e-82 275.8 0.3 4.7e-82 275.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAO83266.1 - 1.5e-45 153.7 1.6 1.5e-45 153.7 1.1 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 GAO83266.1 - 2e-36 124.8 2.2 2e-36 124.8 1.5 3.6 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 GAO83266.1 - 3.6e-14 52.3 0.0 1.3e-13 50.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO83266.1 - 6.4e-08 32.6 0.1 5.5e-07 29.5 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAO83266.1 - 4.7e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 GAO83266.1 - 0.022 14.6 0.1 0.11 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.10 GAO83266.1 - 0.028 13.8 0.1 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 SpoU_methylase PF00588.14 GAO83267.1 - 2.1e-27 95.7 0.0 2.3e-26 92.3 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAO83267.1 - 4.8e-08 33.0 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 GAO83268.1 - 2e-73 245.4 9.7 4.6e-73 244.2 6.8 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 GAO83268.1 - 4.8e-59 199.5 0.6 6.6e-59 199.1 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 GAO83268.1 - 1.9e-15 56.4 1.2 3.6e-15 55.5 0.8 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 GAO83268.1 - 2.2e-12 46.6 0.0 5.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 GAO83268.1 - 2.8e-09 36.5 1.8 2.6e-05 23.8 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 GAO83268.1 - 2.2e-07 30.4 13.8 4.1e-06 26.3 1.9 3.0 2 1 1 3 3 3 2 PHD-finger SnAC PF14619.1 GAO83268.1 - 0.0043 17.1 1.9 0.027 14.6 0.6 2.7 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex PHD_2 PF13831.1 GAO83268.1 - 7.4 5.9 15.1 0.033 13.5 2.6 3.0 3 1 0 3 3 3 0 PHD-finger MRP-S28 PF10213.4 GAO83270.1 - 1e-43 148.4 0.1 1.8e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DIM1 PF02966.11 GAO83270.1 - 0.13 11.7 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Mitosis protein DIM1 Actin PF00022.14 GAO83271.1 - 8e-133 442.6 0.0 1e-132 442.3 0.0 1.1 1 0 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.11 GAO83271.1 - 1e-17 64.3 0.0 1.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 GAO83271.1 - 0.0043 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 DUF3602 PF12223.3 GAO83272.1 - 1.8e-18 66.6 5.7 1.5e-16 60.5 1.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Glyco_hydro_16 PF00722.16 GAO83273.1 - 7.1e-09 35.2 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-U1 PF06220.7 GAO83274.1 - 2.4e-06 26.9 0.9 3.1e-06 26.6 0.6 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.7 GAO83275.1 - 1.7e-162 541.0 27.0 2.6e-162 540.4 18.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAO83275.1 - 2.5e-46 157.2 0.3 3.9e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 GAO83275.1 - 0.0022 17.3 0.0 0.0066 15.8 0.0 1.8 1 0 0 1 1 1 1 Glycoprotein UL132 OppC_N PF12911.2 GAO83275.1 - 0.69 9.3 0.0 0.69 9.3 0.0 4.4 5 0 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C DUF843 PF05814.6 GAO83275.1 - 0.99 9.2 10.1 5.6 6.8 0.1 3.6 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) DEAD PF00270.24 GAO83276.1 - 7.7e-44 149.1 0.1 1.5e-43 148.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO83276.1 - 2.8e-21 75.1 0.0 6.8e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAO83276.1 - 2.8e-21 74.8 0.1 5.1e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAO83276.1 - 0.49 10.2 6.6 0.69 9.7 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Daxx PF03344.10 GAO83276.1 - 1.8 6.9 22.7 2.5 6.4 15.7 1.1 1 0 0 1 1 1 0 Daxx Family FAM60A PF15396.1 GAO83276.1 - 2.8 7.6 10.7 5.6 6.6 7.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 GAO83276.1 - 6.7 4.6 13.2 9.8 4.0 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DZR PF12773.2 GAO83277.1 - 0.41 10.5 0.6 0.85 9.4 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon SOBP PF15279.1 GAO83278.1 - 0.29 11.4 5.5 0.36 11.1 3.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein HAD_2 PF13419.1 GAO83279.1 - 1.4e-11 44.9 0.1 0.00014 22.1 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO83279.1 - 1.3e-09 38.8 0.0 4.9e-07 30.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO83279.1 - 3.8e-08 32.9 0.1 7.8e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 GAO83279.1 - 1.7e-06 28.3 0.0 2.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 GAO83279.1 - 0.015 14.6 0.0 0.66 9.3 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial PGP phosphatase ORMDL PF04061.9 GAO83281.1 - 5.4e-61 204.1 4.1 6.2e-61 203.9 2.9 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 GAO83281.1 - 0.11 12.2 2.1 0.12 12.0 0.8 1.6 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CAF-1_p150 PF11600.3 GAO83283.1 - 6.1e-05 22.4 38.3 6.1e-05 22.4 26.6 3.4 2 1 1 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CH PF00307.26 GAO83283.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 GAO83284.1 - 1.3e-14 54.5 0.2 1.3e-14 54.5 0.2 2.2 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PPDFL PF15060.1 GAO83285.1 - 0.63 10.0 11.0 0.041 13.8 2.7 2.7 2 1 2 4 4 4 0 Differentiation and proliferation regulator DUF1983 PF09327.6 GAO83287.1 - 0.0013 18.6 0.4 0.0028 17.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1983) WD40 PF00400.27 GAO83288.1 - 4.5e-58 191.1 22.0 3.2e-11 42.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat EMP24_GP25L PF01105.19 GAO83288.1 - 2.7e-40 138.0 0.0 5e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 GAO83288.1 - 3e-23 81.2 0.3 6.2e-23 80.2 0.2 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Nup160 PF11715.3 GAO83288.1 - 0.0009 17.4 4.3 0.53 8.3 0.1 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAO83288.1 - 0.044 12.0 0.0 4.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain tRNA_deacylase PF04414.7 GAO83288.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase TPR_12 PF13424.1 GAO83289.1 - 8.6e-13 48.0 9.2 0.00017 21.4 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAO83289.1 - 3.7e-09 35.8 8.4 0.0038 16.7 0.5 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO83289.1 - 3e-05 23.4 12.8 0.039 13.7 0.5 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO83289.1 - 6.9e-05 22.4 11.9 0.28 10.8 0.7 4.7 4 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAO83289.1 - 0.0018 18.0 4.0 0.012 15.5 1.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAO83289.1 - 0.0054 16.4 11.6 0.73 9.7 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAO83289.1 - 0.051 13.5 15.3 0.22 11.5 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAO83289.1 - 0.054 13.7 3.3 2 8.8 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83289.1 - 0.15 12.7 13.4 1 10.0 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO83289.1 - 0.5 10.9 0.1 0.5 10.9 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83289.1 - 7.7 7.4 17.5 7.9 7.4 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF159 PF02586.9 GAO83290.1 - 5.7e-56 189.3 0.0 8.7e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Med1 PF10744.4 GAO83292.1 - 4.8e-115 384.4 0.0 6.8e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.19 GAO83293.1 - 1.4e-60 204.6 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 GAO83293.1 - 2.7e-20 71.7 0.0 4.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 GAO83294.1 - 4.2e-32 111.2 28.8 4.2e-32 111.2 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Choline_transpo PF04515.7 GAO83294.1 - 0.014 14.1 3.7 0.03 13.0 2.5 1.6 1 1 0 1 1 1 0 Plasma-membrane choline transporter UNC-93 PF05978.11 GAO83294.1 - 0.17 11.4 5.4 0.27 10.7 3.1 1.7 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAO83296.1 - 5e-105 351.6 29.8 5.9e-105 351.4 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83296.1 - 2.4e-22 79.1 35.1 1.8e-18 66.4 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAO83296.1 - 0.0022 16.1 7.6 0.16 10.0 0.1 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family zf-CCHC PF00098.18 GAO83297.1 - 1.2e-51 170.2 92.5 1.4e-06 27.8 0.4 11.3 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.1 GAO83297.1 - 2.4e-08 33.5 63.9 0.039 13.6 0.3 10.2 3 2 8 11 11 11 8 Zinc knuckle zf-CCHC_4 PF14392.1 GAO83297.1 - 4.3e-08 32.7 70.1 0.032 13.8 0.2 11.1 11 1 1 12 12 12 7 Zinc knuckle zf-CCHC_6 PF15288.1 GAO83297.1 - 2.6e-06 26.9 73.5 0.00015 21.3 0.4 10.3 8 2 2 10 10 10 6 Zinc knuckle zf-CCHC_2 PF13696.1 GAO83297.1 - 1.5e-05 24.4 40.7 0.014 14.9 0.6 8.1 6 3 3 9 9 9 4 Zinc knuckle Myb_DNA-binding PF00249.26 GAO83298.1 - 0.0026 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Macoilin PF09726.4 GAO83298.1 - 0.014 13.7 20.9 0.048 11.9 14.5 1.7 1 1 0 1 1 1 0 Transmembrane protein CALCOCO1 PF07888.6 GAO83298.1 - 0.086 11.1 12.1 0.025 12.8 4.1 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like RRF_GI PF12614.3 GAO83298.1 - 0.27 11.0 5.4 0.099 12.4 1.2 2.1 2 0 0 2 2 2 0 Ribosome recycling factor EzrA PF06160.7 GAO83298.1 - 2 6.5 17.8 0.0069 14.6 5.7 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Seadorna_VP6 PF07407.6 GAO83298.1 - 3 6.5 6.7 0.63 8.7 1.9 1.7 2 0 0 2 2 2 0 Seadornavirus VP6 protein Fmp27_WPPW PF10359.4 GAO83298.1 - 5.8 5.1 14.4 0.34 9.2 4.4 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 GAO83298.1 - 5.9 5.8 19.2 0.17 10.9 7.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 GAO83298.1 - 5.9 6.0 13.5 0.12 11.6 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF846 PF05832.7 GAO83299.1 - 1.6e-48 164.0 10.6 1.9e-48 163.7 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 GAO83299.1 - 1.9 8.5 9.4 1.6 8.7 0.6 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF1430 PF07242.6 GAO83299.1 - 3.6 7.7 9.9 2.9 8.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) HpcH_HpaI PF03328.9 GAO83300.1 - 1.2e-40 138.7 0.0 3.3e-39 134.0 0.0 2.1 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 GAO83300.1 - 4.8e-13 48.6 0.0 2.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.5 GAO83301.1 - 6.8e-17 61.2 10.2 1.5e-16 60.0 7.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAO83301.1 - 2.6e-13 49.9 0.7 1.8e-12 47.2 0.1 2.8 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 GAO83301.1 - 1.1e-06 28.1 1.4 0.0045 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 GAO83301.1 - 0.019 14.4 0.1 0.071 12.6 0.0 2.0 1 0 0 1 1 1 0 CUE domain SNARE_assoc PF09335.6 GAO83302.1 - 5.3e-12 46.0 6.0 5.3e-12 46.0 4.2 2.5 1 1 1 2 2 2 1 SNARE associated Golgi protein E1-E2_ATPase PF00122.15 GAO83302.1 - 0.041 12.9 1.0 0.41 9.6 0.1 2.4 3 0 0 3 3 3 0 E1-E2 ATPase RskA PF10099.4 GAO83302.1 - 0.061 13.0 0.5 0.061 13.0 0.4 2.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA HAMP PF00672.20 GAO83302.1 - 4.9 7.4 0.0 4.9 7.4 0.0 3.5 4 0 0 4 4 4 0 HAMP domain DUF2207 PF09972.4 GAO83302.1 - 7.4 5.0 12.4 1.9 6.9 0.0 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Amino_oxidase PF01593.19 GAO83303.1 - 2.1e-91 307.2 0.0 4.2e-91 306.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO83303.1 - 3.5e-08 33.3 0.1 7.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 GAO83303.1 - 0.00059 20.0 1.4 0.00059 20.0 1.0 2.3 1 1 1 2 2 2 1 HMG (high mobility group) box NAD_binding_9 PF13454.1 GAO83303.1 - 0.0051 16.6 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 GAO83303.1 - 0.006 15.5 0.4 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO83303.1 - 0.06 13.4 0.1 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO83303.1 - 0.087 12.6 0.1 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO83304.1 - 2.3e-26 92.9 0.1 3.3e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO83304.1 - 5.8e-17 61.8 0.3 1.3e-13 51.1 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO83304.1 - 7.4e-10 39.2 0.3 1.2e-05 25.4 0.0 3.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO83304.1 - 3.1e-05 23.9 0.2 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO83304.1 - 0.00011 21.1 5.4 0.68 8.7 0.1 4.0 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAO83304.1 - 0.00012 22.3 0.5 0.028 14.6 0.0 2.8 3 1 0 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.12 GAO83304.1 - 0.00023 20.3 1.0 0.00061 18.9 0.0 2.1 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 GAO83304.1 - 0.00024 20.1 0.0 0.23 10.3 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAO83304.1 - 0.0017 17.4 0.3 1.4 7.8 0.0 2.7 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 GAO83304.1 - 0.0019 18.3 0.4 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 GAO83304.1 - 0.0052 15.6 7.0 0.57 8.9 0.0 4.0 4 1 1 5 5 5 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAO83304.1 - 0.015 14.3 1.0 1.2 8.1 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO83304.1 - 0.079 11.7 6.0 0.11 11.2 0.2 3.3 3 1 2 5 5 5 0 FAD binding domain HI0933_like PF03486.9 GAO83304.1 - 0.091 11.2 0.8 0.78 8.1 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 GAO83304.1 - 0.13 10.8 0.1 0.41 9.1 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_S8 PF00082.17 GAO83306.1 - 3e-54 184.0 1.2 4.5e-54 183.5 0.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 GAO83306.1 - 3e-30 103.8 0.7 5.8e-30 102.9 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF4366 PF14283.1 GAO83306.1 - 0.089 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PX PF00787.19 GAO83307.1 - 1.4e-17 63.5 0.1 3.3e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 GAO83307.1 - 7.2e-16 58.1 5.6 6.8e-08 32.0 1.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 GAO83307.1 - 0.0016 17.9 3.1 0.0061 16.1 2.1 2.0 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 GAO83307.1 - 0.014 15.4 0.1 0.056 13.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Occludin_ELL PF07303.8 GAO83307.1 - 0.025 15.2 0.1 3.1 8.5 0.0 2.9 2 0 0 2 2 2 0 Occludin homology domain Laminin_II PF06009.7 GAO83307.1 - 0.1 12.3 0.8 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF724 PF05266.9 GAO83307.1 - 0.2 11.2 3.7 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 GAO83307.1 - 0.24 11.3 1.6 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 GAO83307.1 - 0.24 11.1 1.9 5.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 GAO83307.1 - 0.35 10.6 3.5 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.5 GAO83307.1 - 0.46 10.5 1.3 29 4.7 0.2 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FAD_binding_3 PF01494.14 GAO83309.1 - 1.6e-20 73.4 0.1 3.2e-18 65.9 0.1 2.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 GAO83309.1 - 2e-06 26.8 0.0 3.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 GAO83309.1 - 0.00086 18.3 0.1 0.0028 16.6 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO83309.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO83309.1 - 0.025 13.0 0.0 0.039 12.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 GAO83309.1 - 0.025 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO83309.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO83309.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family tRNA-synt_His PF13393.1 GAO83310.1 - 2.8e-37 128.4 0.0 3.8e-31 108.2 0.0 2.4 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAO83310.1 - 1.4e-15 57.3 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAO83310.1 - 1.2e-11 44.4 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 GAO83310.1 - 0.028 13.1 0.1 0.42 9.3 0.0 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) UCH PF00443.24 GAO83311.1 - 2e-64 217.3 0.2 4.2e-64 216.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_22 PF03901.12 GAO83311.1 - 3.2e-39 135.1 19.7 4.4e-39 134.6 13.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UCH_1 PF13423.1 GAO83311.1 - 3.1e-29 102.3 5.2 1.2e-21 77.4 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF912 PF06024.7 GAO83311.1 - 0.072 13.1 1.4 8 6.5 1.3 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_C98 PF15499.1 GAO83311.1 - 0.1 11.8 3.9 0.27 10.4 1.1 2.5 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Dynamitin PF04912.9 GAO83312.1 - 8.9e-32 110.3 4.1 5.3e-16 58.4 0.6 2.7 2 2 0 3 3 3 2 Dynamitin DUF1664 PF07889.7 GAO83312.1 - 0.0035 17.1 2.9 0.8 9.5 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Laminin_II PF06009.7 GAO83312.1 - 0.0036 17.0 11.4 0.0094 15.7 0.2 3.5 2 1 2 4 4 4 1 Laminin Domain II GrpE PF01025.14 GAO83312.1 - 0.013 15.0 5.8 2 7.9 0.1 3.5 3 0 0 3 3 3 0 GrpE ATG16 PF08614.6 GAO83312.1 - 0.022 14.6 0.9 0.022 14.6 0.6 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FH2 PF02181.18 GAO83312.1 - 0.049 12.5 2.2 2.2 7.0 0.4 2.4 2 1 0 2 2 2 0 Formin Homology 2 Domain IFT57 PF10498.4 GAO83312.1 - 0.06 12.0 6.4 0.33 9.6 1.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF241 PF03087.9 GAO83312.1 - 0.1 12.1 6.3 0.35 10.3 1.0 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Spc7 PF08317.6 GAO83312.1 - 0.13 10.8 9.0 1.1 7.7 0.2 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Vac_Fusion PF02346.11 GAO83312.1 - 0.23 10.9 5.8 6.4 6.2 0.4 3.5 3 0 0 3 3 3 0 Chordopoxvirus fusion protein TBPIP PF07106.8 GAO83312.1 - 0.28 10.7 8.2 0.81 9.2 0.4 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 GAO83312.1 - 0.34 10.9 14.3 3.4 7.7 0.4 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 GAO83312.1 - 0.43 9.7 6.9 2.9 7.0 0.1 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 GAO83312.1 - 0.84 9.5 15.5 0.45 10.4 1.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 GAO83312.1 - 0.96 7.7 6.3 2.1 6.6 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF342) ALIX_LYPXL_bnd PF13949.1 GAO83312.1 - 1.2 8.0 13.4 1.2 8.0 1.0 3.1 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV Vfa1 PF08432.5 GAO83312.1 - 1.2 9.1 9.7 5 7.1 0.2 3.0 2 1 1 3 3 3 0 AAA-ATPase Vps4-associated protein 1 PEARLI-4 PF05278.7 GAO83312.1 - 1.3 8.3 7.8 4.5 6.5 0.3 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spectrin PF00435.16 GAO83312.1 - 1.5 9.1 11.5 4.2 7.7 1.5 3.4 2 1 0 3 3 3 0 Spectrin repeat Tropomyosin_1 PF12718.2 GAO83312.1 - 1.9 8.3 19.6 0.16 11.8 1.7 3.5 3 1 0 3 3 3 0 Tropomyosin like THOC7 PF05615.8 GAO83312.1 - 2.5 8.3 10.2 0.21 11.8 0.5 2.8 2 1 0 3 3 3 0 Tho complex subunit 7 DivIC PF04977.10 GAO83312.1 - 3.1 7.3 12.5 0.9 9.0 0.1 3.7 4 0 0 4 4 4 0 Septum formation initiator Fib_alpha PF08702.5 GAO83312.1 - 3.6 7.7 8.3 13 5.9 0.1 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2681 PF10883.3 GAO83312.1 - 3.8 7.7 9.9 15 5.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Pox_A_type_inc PF04508.7 GAO83312.1 - 4.9 7.1 8.1 15 5.6 0.4 3.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SPX PF03105.14 GAO83312.1 - 5.6 6.6 6.4 6.3 6.4 0.6 2.6 2 1 0 3 3 3 0 SPX domain CENP-Q PF13094.1 GAO83312.1 - 5.7 6.9 16.9 3.3 7.6 0.3 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Aldedh PF00171.17 GAO83314.1 - 3.1e-135 451.1 0.4 3.8e-135 450.8 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO83314.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 GAO83315.1 - 1.1e-164 547.4 17.3 1.1e-164 547.4 12.0 1.8 2 0 0 2 2 2 1 Calreticulin family Aldolase_II PF00596.16 GAO83316.1 - 1.2e-40 139.0 0.0 1.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 GAO83317.1 - 6.5e-89 297.2 3.8 1e-88 296.5 2.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAO83317.1 - 6e-26 90.4 0.1 1.4e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 GAO83317.1 - 0.005 15.8 1.2 0.01 14.8 0.8 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking His_Phos_2 PF00328.17 GAO83317.1 - 0.032 13.5 0.4 0.064 12.5 0.3 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 GAO83317.1 - 0.072 12.5 5.1 0.11 11.9 3.6 1.3 1 0 0 1 1 1 0 BAR domain DUF1401 PF07180.6 GAO83318.1 - 0.016 14.9 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) Flavin_Reduct PF01613.13 GAO83319.1 - 1.6e-29 102.7 0.2 2.3e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Methyltransf_25 PF13649.1 GAO83321.1 - 2e-08 34.5 0.0 3.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO83321.1 - 5.5e-07 29.9 0.0 9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83321.1 - 1.1e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83321.1 - 0.00042 20.8 0.0 0.001 19.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83321.1 - 0.00073 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83321.1 - 0.00082 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO83321.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Peripla_BP_3 PF13377.1 GAO83321.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Methyltransf_12 PF08242.7 GAO83321.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 GAO83322.1 - 3.7e-19 69.6 0.1 6.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 GAO83322.1 - 7.4e-19 66.9 6.9 1.5e-10 40.4 1.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO83322.1 - 7.2e-18 64.1 20.7 4.2e-09 36.0 3.1 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAO83322.1 - 3e-08 32.5 6.3 0.021 14.7 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 GAO83322.1 - 1e-06 27.9 10.2 0.47 10.8 0.1 4.8 4 0 0 4 4 4 3 Leucine rich repeat Macoilin PF09726.4 GAO83322.1 - 0.036 12.3 2.2 0.046 12.0 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein UCR_6-4kD PF08997.5 GAO83322.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Neur_chan_memb PF02932.11 GAO83322.1 - 2.8 7.7 5.5 5.7 6.7 3.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LRR_6 PF13516.1 GAO83322.1 - 2.9 8.2 13.1 7.3 6.9 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat GCD14 PF08704.5 GAO83323.1 - 8.6e-06 25.4 0.7 0.031 13.7 0.0 2.7 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit HAD PF12710.2 GAO83324.1 - 1.4e-09 38.4 0.0 5.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.23 GAO83324.1 - 2.5e-09 36.8 0.1 1.5e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO83324.1 - 3.7e-05 23.6 0.1 0.00019 21.2 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain HAD_2 PF13419.1 GAO83324.1 - 0.001 19.3 0.0 0.0036 17.5 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAO83324.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) P22_CoatProtein PF11651.3 GAO83324.1 - 0.33 9.4 0.0 0.49 8.9 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 NAD_binding_6 PF08030.7 GAO83325.1 - 7.9e-05 22.6 0.0 0.00043 20.2 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAO83325.1 - 0.00044 20.7 0.0 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MARVEL PF01284.18 GAO83326.1 - 0.022 14.5 2.0 0.045 13.5 1.4 1.5 1 1 0 1 1 1 0 Membrane-associating domain GATA PF00320.22 GAO83327.1 - 9.6e-17 60.0 4.5 2e-16 59.0 3.1 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 GAO83327.1 - 8e-09 35.8 0.0 2.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 GAO83327.1 - 2.2e-08 34.0 0.0 5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 GAO83327.1 - 1.1e-05 25.1 0.0 5.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 GAO83327.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 GAO83327.1 - 0.005 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 GAO83327.1 - 0.11 11.8 0.6 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding SbcCD_C PF13558.1 GAO83328.1 - 1.1e-11 44.4 0.0 3.8e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit KNOX2 PF03791.8 GAO83328.1 - 9.5e-05 21.5 1.1 0.0059 15.8 0.2 3.9 3 0 0 3 3 3 1 KNOX2 domain AAA_13 PF13166.1 GAO83328.1 - 0.0034 15.9 124.1 0.0099 14.3 4.0 5.7 1 1 4 5 5 5 5 AAA domain AAA_21 PF13304.1 GAO83328.1 - 0.057 13.3 11.1 0.059 13.3 4.1 3.4 2 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 GAO83328.1 - 0.98 8.5 34.1 1.4 7.9 1.2 7.0 4 2 3 7 7 7 0 Reovirus sigma C capsid protein Rad1 PF02144.11 GAO83329.1 - 8.7e-100 333.0 0.0 1e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.20 GAO83330.1 - 1.6e-26 92.0 1.2 3.1e-26 91.1 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAO83330.1 - 9.7e-10 38.4 0.1 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO83330.1 - 3.2e-09 36.6 0.1 8.8e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RGS PF00615.14 GAO83331.1 - 8.9e-12 45.1 0.0 8.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain PrgI PF12666.2 GAO83331.1 - 1.5 9.0 5.9 0.46 10.6 0.7 2.2 1 1 1 2 2 2 0 PrgI family protein PCI PF01399.22 GAO83332.1 - 2.1e-06 27.9 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 PCI domain E1-E2_ATPase PF00122.15 GAO83333.1 - 3.3e-50 170.2 0.2 8e-50 169.0 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 GAO83333.1 - 1.6e-46 156.2 2.5 1e-12 47.9 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 GAO83333.1 - 1.4e-43 149.7 0.1 3.8e-43 148.4 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO83333.1 - 3.3e-16 60.0 0.0 7.9e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO83333.1 - 2.5e-05 24.0 0.9 0.00052 19.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 GAO83333.1 - 0.055 13.0 0.9 16 5.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) DUF4001 PF13165.1 GAO83333.1 - 0.64 9.7 3.7 6.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4001) PPP4R2 PF09184.6 GAO83334.1 - 2.3e-10 40.4 7.0 9e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 PPP4R2 AIRC PF00731.15 GAO83335.1 - 7.1e-58 194.1 2.1 1.6e-57 192.9 1.5 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 GAO83335.1 - 2.5e-53 179.9 0.0 7.5e-53 178.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAO83335.1 - 1.2e-12 47.9 0.0 4.6e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAO83335.1 - 9.9e-07 28.2 0.0 2.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 GAO83335.1 - 9.1e-06 25.1 0.0 0.00013 21.3 0.0 2.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAO83335.1 - 0.00099 17.9 0.0 0.32 9.6 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon NAD_binding_2 PF03446.10 GAO83335.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAO83335.1 - 0.0095 15.9 0.1 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain XdhC_C PF13478.1 GAO83335.1 - 0.0098 16.2 0.0 0.031 14.6 0.0 1.9 1 0 0 1 1 1 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 GAO83335.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.9 GAO83335.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain 3HCDH_N PF02737.13 GAO83335.1 - 0.025 14.2 0.1 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4449 PF14613.1 GAO83336.1 - 9.1e-69 230.5 1.9 9.1e-69 230.5 1.3 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Med23 PF11573.3 GAO83336.1 - 0.06 10.7 0.2 0.086 10.1 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Fungal_trans PF04082.13 GAO83337.1 - 8.7e-22 77.2 0.0 1.3e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83337.1 - 1.8e-08 34.1 8.2 4.1e-08 32.9 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.5 GAO83338.1 - 2.3e-60 204.2 0.2 5.1e-60 203.1 0.2 1.6 1 0 0 1 1 1 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 GAO83338.1 - 1.4e-19 69.9 0.0 2.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBP1_TM PF14812.1 GAO83338.1 - 0.032 14.5 0.7 0.087 13.1 0.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Enkurin PF13864.1 GAO83338.1 - 0.12 12.6 0.1 9.7 6.4 0.2 2.5 2 0 0 2 2 2 0 Calmodulin-binding DUF4202 PF13875.1 GAO83339.1 - 3.2e-83 277.9 0.3 3.6e-83 277.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.14 GAO83340.1 - 2.9e-58 196.8 7.7 2.9e-58 196.8 5.3 2.1 2 0 0 2 2 2 1 VIT family 7TMR-DISM_7TM PF07695.6 GAO83340.1 - 0.0099 15.5 0.4 0.019 14.6 0.3 1.4 1 0 0 1 1 1 1 7TM diverse intracellular signalling VPS9 PF02204.13 GAO83342.1 - 3.1e-20 72.1 0.0 8.1e-20 70.7 0.0 1.7 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 GAO83342.1 - 4.1e-10 38.9 0.4 5.9e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.16 GAO83343.1 - 2.7e-54 184.3 0.0 3.2e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase bZIP_1 PF00170.16 GAO83344.1 - 2.9e-08 33.5 10.1 5.4e-08 32.6 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO83344.1 - 2.9e-07 30.2 11.0 2.9e-07 30.2 7.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper HSBP1 PF06825.7 GAO83344.1 - 0.0048 16.4 0.8 0.0048 16.4 0.5 1.7 2 0 0 2 2 2 1 Heat shock factor binding protein 1 PH_6 PF15406.1 GAO83345.1 - 4.9e-35 119.9 1.6 4.9e-35 119.9 1.1 3.5 4 1 0 4 4 4 1 Pleckstrin homology domain PH PF00169.24 GAO83345.1 - 0.0077 16.4 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.15 GAO83346.1 - 4.8e-42 143.8 9.6 9e-42 142.9 6.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 GAO83346.1 - 1.3e-17 63.3 0.0 2.8e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 GAO83346.1 - 1.8e-11 43.5 0.1 3.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 GAO83347.1 - 2.1e-12 47.3 0.0 6.2e-12 45.7 0.0 1.9 3 0 0 3 3 3 1 GINS complex protein HMG_box PF00505.14 GAO83348.1 - 4.1e-12 46.1 0.4 7.4e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 GAO83348.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 adh_short PF00106.20 GAO83349.1 - 4.5e-17 62.4 0.0 6.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO83349.1 - 6.2e-09 35.7 0.0 7.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO83349.1 - 1e-08 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO83349.1 - 0.0048 16.9 0.1 0.0098 15.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO83349.1 - 0.018 14.5 0.1 0.047 13.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PHD PF00628.24 GAO83350.1 - 2.5e-08 33.4 8.1 5.8e-08 32.3 5.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAO83350.1 - 0.0032 16.7 4.2 0.0032 16.7 2.9 2.1 2 0 0 2 2 2 1 PHD-finger DUF2688 PF10892.3 GAO83350.1 - 1.7 8.3 4.5 0.56 9.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Rcd1 PF04078.8 GAO83351.1 - 3.1e-131 435.9 2.8 3.9e-131 435.6 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Glycophorin_A PF01102.13 GAO83352.1 - 0.057 13.1 3.0 0.061 13.0 0.1 2.5 3 0 0 3 3 3 0 Glycophorin A Prefoldin_2 PF01920.15 GAO83354.1 - 2.2e-17 62.7 5.2 2.7e-17 62.4 3.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PglZ PF08665.7 GAO83354.1 - 0.04 13.5 0.2 0.049 13.3 0.2 1.2 1 0 0 1 1 1 0 PglZ domain Cep57_MT_bd PF06657.8 GAO83354.1 - 0.092 12.7 1.7 0.67 9.9 0.2 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3896 PF13035.1 GAO83354.1 - 0.11 12.5 1.4 0.26 11.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3896) TACC PF05010.9 GAO83354.1 - 0.14 11.8 3.0 0.18 11.5 2.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Fib_alpha PF08702.5 GAO83354.1 - 0.17 12.0 5.5 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 GAO83354.1 - 0.26 11.4 5.8 1 9.5 4.0 1.9 1 1 0 1 1 1 0 Syntaxin Tropomyosin_1 PF12718.2 GAO83354.1 - 0.73 9.6 5.8 0.67 9.7 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 GAO83354.1 - 1.1 9.1 4.3 0.61 9.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 GAO83354.1 - 1.2 9.3 5.5 0.75 9.9 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 GAO83354.1 - 1.3 8.6 7.6 0.28 10.8 0.5 2.2 1 1 2 3 3 3 0 Prefoldin subunit Pox_A_type_inc PF04508.7 GAO83354.1 - 2.8 7.9 5.5 0.77 9.7 0.1 2.8 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat CCDC-167 PF15188.1 GAO83354.1 - 3.2 7.7 5.7 1.1 9.2 1.0 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.22 GAO83356.1 - 4.4e-57 189.8 2.2 3.4e-19 68.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ceramidase PF05875.7 GAO83357.1 - 1.2e-99 332.7 12.6 2.1e-99 331.9 8.7 1.4 1 1 0 1 1 1 1 Ceramidase Abhydrolase_6 PF12697.2 GAO83358.1 - 6e-28 98.2 0.1 9.4e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO83358.1 - 4.9e-06 26.3 0.0 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO83358.1 - 5.6e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAO83358.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein BRCT PF00533.21 GAO83359.1 - 4.4e-39 132.4 0.0 9.7e-09 35.2 0.0 6.3 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAO83359.1 - 9.1e-30 102.3 0.0 8.3e-20 70.4 0.5 5.3 5 1 0 5 5 5 4 twin BRCT domain ESCRT-II PF05871.7 GAO83360.1 - 1.6e-53 180.3 0.0 2.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 GAO83361.1 - 1.5e-47 161.2 0.0 8.4e-36 122.8 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 GAO83361.1 - 2.8e-05 24.6 0.0 6.6e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83361.1 - 0.00034 20.2 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83361.1 - 0.00089 19.2 0.0 0.003 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO83361.1 - 0.0013 18.0 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAO83361.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83361.1 - 0.0054 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAO83361.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 GAO83361.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 GAO83361.1 - 0.077 13.4 0.0 0.53 10.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain LIM PF00412.17 GAO83362.1 - 5.4e-28 96.8 23.7 5.3e-10 39.2 2.6 3.8 3 1 0 3 3 3 3 LIM domain DUF3725 PF12523.3 GAO83362.1 - 0.035 14.2 4.9 0.6 10.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3725) MFS_1 PF07690.11 GAO83363.1 - 1.8e-21 76.2 48.9 1.6e-20 73.1 33.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily RNB PF00773.14 GAO83364.1 - 1.3e-95 320.4 0.1 1.9e-95 319.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 GAO83364.1 - 2e-10 40.8 0.1 5.2e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 PIN domain Peptidase_C37 PF05416.7 GAO83364.1 - 1.4 7.1 5.5 0.38 8.9 0.3 2.1 2 0 0 2 2 2 0 Southampton virus-type processing peptidase CN_hydrolase PF00795.17 GAO83365.1 - 1.1e-21 77.0 0.0 1.9e-21 76.2 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ESSS PF10183.4 GAO83366.1 - 5.8e-30 103.8 0.1 6.5e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 GAO83366.1 - 0.14 11.7 0.5 0.23 11.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Dna2 PF08696.6 GAO83367.1 - 1.7e-74 249.6 0.3 2.8e-74 248.9 0.2 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 GAO83367.1 - 1.8e-53 180.9 0.0 3.2e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAO83367.1 - 5.5e-41 140.6 0.2 1.6e-20 73.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 GAO83367.1 - 2.4e-13 50.1 0.0 5.6e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO83367.1 - 1.2e-11 44.2 0.3 3.8e-11 42.5 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 GAO83367.1 - 1.4e-11 44.2 0.0 4.5e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 GAO83367.1 - 1.2e-06 28.5 0.0 3.6e-06 26.9 0.0 1.8 2 0 0 2 2 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 GAO83367.1 - 1.2e-06 28.2 0.2 0.37 10.2 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 GAO83367.1 - 9.1e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF911 PF06023.7 GAO83367.1 - 9.6e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) CbiA PF01656.18 GAO83367.1 - 0.00025 20.5 0.0 0.00059 19.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 GAO83367.1 - 0.00027 20.3 0.1 0.00076 18.8 0.1 1.8 2 0 0 2 2 1 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 GAO83367.1 - 0.00084 19.0 0.1 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 GAO83367.1 - 0.001 18.5 0.6 0.0024 17.3 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 GAO83367.1 - 0.0014 18.6 0.0 0.0047 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 GAO83367.1 - 0.0039 16.2 0.1 0.018 14.0 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_25 PF13481.1 GAO83367.1 - 0.02 14.3 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAO83367.1 - 0.028 13.3 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 GAO83367.1 - 0.029 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 GAO83367.1 - 0.034 13.9 0.2 0.14 11.9 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 GAO83367.1 - 0.054 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 GAO83367.1 - 0.059 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 GAO83367.1 - 0.062 13.4 0.1 0.29 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAO83367.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 GAO83367.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein ResIII PF04851.10 GAO83367.1 - 0.15 11.9 1.9 0.52 10.1 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 GAO83367.1 - 0.16 11.4 0.5 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ribonuc_P_40 PF08584.6 GAO83368.1 - 5.7e-91 304.4 0.0 7.4e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 GAO83369.1 - 1.8e-34 116.3 14.0 5.1e-10 38.8 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAO83369.1 - 2.2e-08 32.8 0.0 2.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 GAO83369.1 - 5.1e-06 26.3 0.0 0.18 11.4 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAO83369.1 - 0.0016 17.8 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 GAO83369.1 - 0.011 13.8 0.1 0.26 9.3 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 GAO83369.1 - 0.13 10.9 0.0 0.98 8.1 0.0 2.1 2 1 1 3 3 3 0 Coatomer WD associated region Fungal_trans PF04082.13 GAO83370.1 - 1.4e-19 70.0 0.1 2.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83370.1 - 2.1e-09 37.1 9.7 4.1e-09 36.2 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-F_leu_zip PF10473.4 GAO83370.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L2_C PF03947.13 GAO83371.1 - 1.2e-47 160.9 1.3 3e-33 114.3 0.7 2.5 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAO83371.1 - 1.7e-27 95.2 0.1 3e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.19 GAO83371.1 - 0.057 13.2 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 PAS fold Cyclin_N PF00134.18 GAO83372.1 - 1.2e-45 154.1 0.2 1.2e-44 150.9 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAO83372.1 - 5.5e-29 100.4 0.0 1.2e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 GAO83372.1 - 1.3e-16 60.8 0.1 3.6e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAO83372.1 - 4.1e-05 23.7 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAO83372.1 - 0.046 13.3 0.6 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 GAO83373.1 - 6.5e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 GAO83373.1 - 9.1e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 GAO83373.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 GAO83373.1 - 0.07 12.6 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 DNA methylase SIR2 PF02146.12 GAO83374.1 - 1.5e-60 203.9 0.0 2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 GAO83374.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 GAO83374.1 - 0.035 13.8 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.1 GAO83375.1 - 1.3e-12 47.4 1.1 1.3e-07 31.4 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO83375.1 - 1.8e-10 40.3 7.5 1.8e-05 24.2 0.0 4.8 2 1 3 5 5 5 3 TPR repeat TPR_16 PF13432.1 GAO83375.1 - 1.7e-09 38.0 12.3 0.00019 22.0 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO83375.1 - 2.1e-09 36.5 7.8 0.00024 20.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO83375.1 - 4.1e-08 32.4 0.0 0.0083 15.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO83375.1 - 6.3e-08 32.8 16.7 0.00023 21.4 0.1 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAO83375.1 - 1.1e-07 31.2 1.2 0.001 18.5 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83375.1 - 1.2e-06 28.5 17.8 0.018 15.6 1.0 6.1 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAO83375.1 - 1.8e-05 24.4 15.0 0.23 11.3 1.4 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO83375.1 - 2.7e-05 24.2 0.1 0.038 14.1 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAO83375.1 - 0.00079 19.4 0.1 24 5.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 GAO83375.1 - 0.0011 18.2 0.5 0.43 9.7 0.1 2.3 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_7 PF13176.1 GAO83375.1 - 0.0014 18.2 6.3 0.018 14.8 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAO83375.1 - 0.0046 16.0 0.0 0.0046 16.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO83375.1 - 0.0091 16.3 10.2 1.9 9.1 0.1 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.5 GAO83375.1 - 0.011 14.5 0.5 0.37 9.5 0.0 2.4 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 GAO83375.1 - 0.079 12.9 0.1 0.079 12.9 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO83375.1 - 0.1 12.5 11.7 2.3 8.2 0.2 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Vps39_1 PF10366.4 GAO83375.1 - 0.36 10.8 7.4 0.15 12.0 0.3 3.3 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RWD PF05773.17 GAO83376.1 - 1.2e-23 83.1 0.9 2.2e-23 82.2 0.6 1.4 1 0 0 1 1 1 1 RWD domain Ctr PF04145.10 GAO83376.1 - 1.2 9.2 4.0 0.63 10.0 0.7 1.8 1 1 1 2 2 2 0 Ctr copper transporter family Complex1_LYR_1 PF13232.1 GAO83377.1 - 2.7e-16 59.5 0.2 1.1e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAO83377.1 - 3.8e-16 58.6 0.2 1.3e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) MutS_II PF05188.12 GAO83377.1 - 0.044 13.8 0.5 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 MutS domain II Snf7 PF03357.16 GAO83377.1 - 0.12 11.8 3.1 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 Snf7 Occludin_ELL PF07303.8 GAO83377.1 - 0.18 12.5 2.7 0.66 10.7 0.3 2.3 2 0 0 2 2 2 0 Occludin homology domain UQ_con PF00179.21 GAO83378.1 - 1.8e-17 63.0 0.0 2.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAO83378.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 GAO83379.1 - 4.7e-42 143.2 4.5 2.4e-41 140.9 0.0 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Vps26 PF03643.10 GAO83380.1 - 3.5e-130 432.7 0.2 4.3e-130 432.4 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAO83380.1 - 0.00051 19.8 0.8 1.1 9.1 0.0 3.2 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAO83380.1 - 0.039 14.0 0.1 0.24 11.5 0.0 2.3 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF432 PF04254.8 GAO83380.1 - 0.042 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) SKI PF01202.17 GAO83381.1 - 4e-15 56.0 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 GAO83381.1 - 4e-10 40.5 0.0 5.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO83381.1 - 2.8e-09 37.3 0.0 5.8e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO83381.1 - 2.8e-09 36.9 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAO83381.1 - 3.2e-05 22.8 0.0 4.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 GAO83381.1 - 0.0074 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 GAO83381.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family PRK PF00485.13 GAO83381.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 GAO83381.1 - 0.016 14.5 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 MutS domain V APS_kinase PF01583.15 GAO83381.1 - 0.017 14.7 0.0 0.028 14.1 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.1 GAO83381.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAO83381.1 - 0.022 14.9 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 GAO83381.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 GAO83381.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 GAO83381.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 GAO83381.1 - 0.062 13.2 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAO83381.1 - 0.063 12.4 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CoaE PF01121.15 GAO83381.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_16 PF13191.1 GAO83381.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain tRNA_lig_kinase PF08303.6 GAO83381.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 tRNA ligase kinase domain Viral_helicase1 PF01443.13 GAO83381.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.12 GAO83381.1 - 0.12 11.7 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Prenyltrans PF00432.16 GAO83382.1 - 8.9e-29 98.7 5.0 1.8e-10 40.1 0.3 4.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAO83382.1 - 1.5e-24 86.5 0.1 3.8e-16 59.4 0.0 4.7 3 1 2 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAO83382.1 - 7.6e-22 77.3 0.0 1.1e-12 47.9 0.0 5.2 3 2 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 GAO83382.1 - 1.3e-06 27.7 0.6 0.28 10.3 0.0 4.7 4 2 1 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 GAO83382.1 - 0.00012 21.3 0.3 0.0011 18.3 0.0 2.5 1 1 2 3 3 3 1 A-macroglobulin complement component Chromadorea_ALT PF05535.7 GAO83382.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Chromadorea ALT protein DUF4632 PF15451.1 GAO83383.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4632) 2-oxoacid_dh PF00198.18 GAO83384.1 - 2.8e-79 265.6 0.1 4.2e-79 265.0 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 GAO83384.1 - 5.2e-12 45.1 0.1 1.3e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 GAO83384.1 - 8.2e-12 44.5 0.0 1.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme PI-PLC-X PF00388.14 GAO83385.1 - 3.4e-13 49.2 0.0 5.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 GAO83386.1 - 0.0053 16.6 0.0 0.065 13.1 0.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.16 GAO83387.1 - 1.4e-58 198.2 0.0 5.7e-57 193.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 GAO83387.1 - 0.00013 21.4 0.3 0.00029 20.3 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain GatB_Yqey PF02637.13 GAO83387.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 GatB domain DNA_RNApol_7kD PF03604.8 GAO83388.1 - 6.5e-17 60.7 5.9 8.2e-17 60.3 4.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 GAO83388.1 - 0.00021 21.1 0.5 0.038 13.9 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 GAO83388.1 - 0.0027 17.5 0.2 0.0038 17.0 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 GAO83388.1 - 0.0086 15.5 2.6 0.067 12.6 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain HypA PF01155.14 GAO83388.1 - 0.017 14.8 0.3 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 GAO83388.1 - 0.018 14.9 0.5 0.03 14.2 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.13 GAO83388.1 - 0.027 14.0 0.4 4.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2318 PF10080.4 GAO83388.1 - 0.033 13.9 0.3 0.04 13.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) GFA PF04828.9 GAO83388.1 - 0.078 12.9 0.6 3.1 7.8 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Prok-RING_1 PF14446.1 GAO83388.1 - 0.091 12.5 0.7 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3268 PF11672.3 GAO83388.1 - 0.13 12.4 0.5 0.61 10.1 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) DUF951 PF06107.6 GAO83388.1 - 0.3 10.6 2.1 1.6 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) RRN7 PF11781.3 GAO83388.1 - 0.71 9.4 3.4 2.6 7.6 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_ribbon_recom PF13408.1 GAO83388.1 - 0.87 9.8 5.4 2.5 8.4 0.9 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 GAO83388.1 - 0.93 9.1 3.7 1.3 8.7 2.6 1.2 1 0 0 1 1 1 0 Ribosomal L40e family zinc_ribbon_4 PF13717.1 GAO83388.1 - 1 9.1 3.3 5.2 6.8 2.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Fe_hyd_lg_C PF02906.9 GAO83389.1 - 4.4e-64 216.4 0.0 7.4e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 GAO83390.1 - 3.7e-37 127.5 0.0 7.5e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 GAO83390.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Macro domain Fapy_DNA_glyco PF01149.19 GAO83391.1 - 5.3e-26 91.2 0.0 8.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 GAO83391.1 - 3.8e-22 77.8 0.0 6.1e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 GAO83391.1 - 0.005 15.4 0.0 0.0083 14.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 GAO83391.1 - 0.04 14.3 0.0 0.097 13.1 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein S13/S18 Cid2 PF09774.4 GAO83392.1 - 4.8e-51 172.8 0.2 6.1e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 RNA_pol_Rpb5_N PF03871.9 GAO83392.1 - 0.054 13.9 0.4 0.094 13.1 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain NARP1 PF12569.3 GAO83393.1 - 5e-218 725.0 24.2 1.7e-215 716.6 13.0 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 GAO83393.1 - 4e-17 61.1 27.6 0.012 16.1 0.1 11.8 8 3 4 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAO83393.1 - 6.8e-17 61.5 41.2 0.0034 17.7 0.3 7.6 6 2 1 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAO83393.1 - 8.3e-17 60.6 41.2 1.9e-06 27.4 0.4 8.6 7 2 2 9 9 9 4 TPR repeat TPR_2 PF07719.12 GAO83393.1 - 3e-13 48.5 47.1 0.00024 20.7 0.3 11.5 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83393.1 - 3.4e-13 49.8 39.3 0.0032 18.0 0.9 9.6 9 1 1 11 11 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAO83393.1 - 1.7e-06 27.8 40.4 0.0052 16.7 0.2 8.3 6 4 2 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO83393.1 - 2e-06 27.5 19.6 1.5 9.2 0.0 8.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAO83393.1 - 1.3e-05 24.9 15.0 0.0029 17.4 1.8 5.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO83393.1 - 3.9e-05 23.0 0.3 3.9e-05 23.0 0.2 9.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO83393.1 - 0.00017 21.1 21.2 0.0086 15.7 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAO83393.1 - 0.0071 16.1 0.2 0.23 11.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO83393.1 - 0.067 13.6 12.3 0.14 12.6 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 GAO83393.1 - 0.086 12.6 1.2 2.2 8.1 0.1 3.5 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.1 GAO83393.1 - 0.51 10.2 15.1 1.9 8.4 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAO83393.1 - 0.75 9.7 21.1 0.88 9.5 0.1 6.4 8 1 1 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat Tim54 PF11711.3 GAO83394.1 - 9e-151 501.7 0.0 1.1e-150 501.5 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 GAO83395.1 - 7e-54 182.7 2.1 9.7e-38 129.7 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83395.1 - 8e-25 87.3 0.5 1.5e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO83395.1 - 6.1e-05 22.1 0.0 0.00013 20.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO83395.1 - 0.00025 20.1 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO83395.1 - 0.00026 20.8 0.2 0.011 15.5 0.1 2.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO83395.1 - 0.0044 15.8 0.0 0.0074 15.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 GAO83395.1 - 0.0087 16.5 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.17 GAO83395.1 - 0.067 12.5 2.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family SpoIIIAH PF12685.2 GAO83395.1 - 0.41 10.1 3.8 0.78 9.1 2.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein BAF1_ABF1 PF04684.8 GAO83395.1 - 0.47 9.2 7.9 0.72 8.6 5.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-met PF12874.2 GAO83396.1 - 1.9e-05 24.6 0.6 3.7e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 GAO83396.1 - 0.046 12.9 0.9 0.094 12.0 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.20 GAO83397.1 - 7.6e-19 67.1 0.2 1.3e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 GAO83397.1 - 6.2e-14 51.2 17.9 5.6e-05 22.6 0.8 5.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO83397.1 - 5.9e-10 38.7 13.5 5.9e-05 22.7 2.4 4.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 GAO83397.1 - 1.5e-07 30.7 9.7 7 7.0 0.0 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 GAO83397.1 - 2.7e-07 29.6 8.6 15 6.1 0.0 7.4 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 GAO83397.1 - 0.013 15.5 9.2 1.1e+02 3.7 0.0 7.2 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 GAO83397.1 - 0.018 14.6 2.7 1.6 8.2 0.1 3.3 1 1 2 4 4 4 0 Leucine-rich repeat zf-U1 PF06220.7 GAO83398.1 - 8.5e-06 25.2 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger PV-1 PF06637.6 GAO83398.1 - 0.012 14.2 0.8 0.012 14.2 0.6 2.1 2 0 0 2 2 2 0 PV-1 protein (PLVAP) CCDC84 PF14968.1 GAO83398.1 - 0.077 12.4 7.6 0.35 10.3 5.3 2.0 1 1 0 1 1 1 0 Coiled coil protein 84 DivIVA PF05103.8 GAO83398.1 - 0.81 9.7 0.1 0.81 9.7 0.0 2.9 2 1 1 3 3 3 0 DivIVA protein Zn_clus PF00172.13 GAO83399.1 - 1.3e-08 34.5 8.3 2.1e-08 33.9 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 GAO83400.1 - 6.2e-57 191.6 0.0 8.6e-57 191.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO83400.1 - 1.3e-14 53.8 0.0 1.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAO83400.1 - 0.00017 21.4 0.2 0.00029 20.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 GAO83400.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 GAO83400.1 - 0.029 14.2 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SHOCT PF09851.4 GAO83400.1 - 0.099 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 Short C-terminal domain CwfJ_C_1 PF04677.10 GAO83401.1 - 7.5e-31 106.3 0.0 3.1e-29 101.0 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAO83401.1 - 7.3e-26 90.5 0.0 3.3e-25 88.4 0.0 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.4 GAO83401.1 - 0.069 13.2 0.4 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus ATP_bind_1 PF03029.12 GAO83402.1 - 1.4e-76 257.2 0.0 2e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 GAO83402.1 - 3e-05 22.9 0.0 0.013 14.3 0.0 2.4 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 GAO83402.1 - 6.6e-05 22.4 0.0 0.0017 17.8 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAO83402.1 - 0.00016 21.7 0.0 0.00051 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAO83402.1 - 0.00024 21.0 0.0 0.00056 19.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAO83402.1 - 0.0021 18.0 0.2 0.086 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 GAO83402.1 - 0.0027 18.1 0.0 2.9 8.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 GAO83402.1 - 0.0031 17.1 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 GAO83402.1 - 0.0035 18.1 0.1 0.01 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 GAO83402.1 - 0.0046 16.4 0.0 0.0091 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 GAO83402.1 - 0.0081 15.4 0.0 0.15 11.3 0.0 2.4 3 0 0 3 3 2 1 Ferrous iron transport protein B SRP54 PF00448.17 GAO83402.1 - 0.0094 15.4 0.0 0.052 12.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 GAO83402.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO83402.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 GAO83402.1 - 0.02 13.5 2.2 0.039 12.5 1.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MobB PF03205.9 GAO83402.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 GAO83402.1 - 0.027 14.0 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 GAO83402.1 - 0.028 13.8 0.1 1.6 8.1 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 GAO83402.1 - 0.034 13.0 0.1 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Methyltransf_32 PF13679.1 GAO83402.1 - 0.039 13.6 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Arf PF00025.16 GAO83402.1 - 0.045 12.9 0.0 16 4.7 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family KAP_NTPase PF07693.9 GAO83402.1 - 0.075 12.0 0.0 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.1 GAO83402.1 - 0.1 12.1 0.0 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAO83402.1 - 0.12 11.8 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 GAO83402.1 - 0.14 11.5 0.0 0.48 9.7 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Daxx PF03344.10 GAO83402.1 - 0.16 10.4 10.3 0.24 9.8 7.2 1.1 1 0 0 1 1 1 0 Daxx Family G-alpha PF00503.15 GAO83402.1 - 0.9 8.1 6.0 1.9 7.0 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit Peptidase_S8 PF00082.17 GAO83403.1 - 3.3e-45 154.4 14.8 5.1e-45 153.7 10.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAO83403.1 - 7.1e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.11 GAO83404.1 - 1.3e-29 103.0 31.0 1.3e-29 103.0 21.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO83404.1 - 5.4e-14 51.6 4.2 5.4e-14 51.6 2.9 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter GST_N_3 PF13417.1 GAO83405.1 - 4.3e-21 74.9 0.0 1.1e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO83405.1 - 3.8e-14 52.4 0.0 1.5e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO83405.1 - 8.5e-05 22.3 0.0 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAO83405.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin 7TM_GPCR_Srab PF10292.4 GAO83405.1 - 0.88 8.2 1.9 1.4 7.5 1.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor SUZ-C PF12901.2 GAO83406.1 - 0.00098 18.6 3.5 0.0027 17.2 2.4 1.8 1 0 0 1 1 1 1 SUZ-C motif SUZ PF12752.2 GAO83406.1 - 0.0026 18.2 6.3 0.0026 18.2 4.3 4.3 2 1 1 3 3 3 1 SUZ domain CRF PF00473.12 GAO83406.1 - 4.4 7.4 5.9 0.54 10.3 0.8 2.0 2 0 0 2 2 2 0 Corticotropin-releasing factor family Herpes_DNAp_acc PF04929.7 GAO83407.1 - 0.16 10.8 3.2 0.19 10.6 2.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Aldo_ket_red PF00248.16 GAO83409.1 - 2.9e-58 196.9 0.0 3.4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 GAO83410.1 - 2.5e-24 85.0 0.0 5.7e-24 83.9 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO83410.1 - 1.8e-18 66.0 0.0 7.9e-18 63.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAO83410.1 - 0.0011 19.2 0.0 0.1 12.8 0.0 2.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO83410.1 - 0.0013 19.1 0.0 0.022 15.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 GAO83411.1 - 3.8e-11 42.6 0.1 7e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO83411.1 - 5.1e-07 29.4 0.1 2.2e-06 27.3 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF1751 PF08551.5 GAO83412.1 - 0.0065 16.7 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.2 GAO83413.1 - 3e-10 40.3 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAO83413.1 - 1.7e-09 37.1 8.0 2.8e-09 36.5 5.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 GAO83413.1 - 0.13 12.4 1.3 0.29 11.3 0.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Transket_pyr PF02779.19 GAO83414.1 - 2.5e-65 219.3 0.0 4.2e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAO83414.1 - 2.7e-56 190.4 0.0 3.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sld5 PF05916.6 GAO83417.1 - 2.5e-13 50.2 0.0 3.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Spc7 PF08317.6 GAO83418.1 - 0.05 12.2 13.3 0.09 11.4 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.1 GAO83418.1 - 0.12 12.7 9.2 0.2 11.9 6.4 1.3 1 0 0 1 1 1 0 AAA domain Microtub_assoc PF07989.6 GAO83418.1 - 0.23 11.3 14.9 0.019 14.7 1.5 2.5 1 1 1 2 2 2 0 Microtubule associated BLOC1_2 PF10046.4 GAO83418.1 - 0.36 10.9 8.4 1.2 9.2 5.8 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 GAO83418.1 - 3.3 8.0 13.2 1.4 9.3 6.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 GAO83418.1 - 3.4 7.6 6.6 12 5.8 4.1 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 GAO83418.1 - 3.8 4.7 22.3 5.5 4.1 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 GAO83418.1 - 3.8 5.2 7.6 6.1 4.5 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 GAO83418.1 - 9.3 5.1 14.3 20 4.0 9.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 GAO83418.1 - 9.5 4.4 6.6 15 3.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sod_Fe_C PF02777.13 GAO83420.1 - 8.9e-40 134.8 1.3 1.2e-39 134.3 0.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAO83420.1 - 1.6e-29 101.9 2.7 2.7e-29 101.2 1.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.7 GAO83421.1 - 8.5e-88 294.2 7.3 1.6e-87 293.4 5.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 GAO83421.1 - 1.3e-17 63.3 1.6 2.8e-17 62.2 1.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAO83421.1 - 2.2e-08 33.8 0.8 2.2e-08 33.8 0.5 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site ATP-synt_E PF05680.7 GAO83421.1 - 0.14 12.0 2.5 0.4 10.6 1.8 1.7 1 0 0 1 1 1 0 ATP synthase E chain DUF1162 PF06650.7 GAO83422.1 - 9.8e-91 303.7 0.0 1.5e-88 296.5 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAO83422.1 - 7e-43 144.9 0.1 1.9e-42 143.5 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAO83422.1 - 1.8e-06 28.0 0.2 1.8e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 GAO83423.1 - 1.2e-41 141.9 9.0 1.7e-41 141.5 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 GAO83424.1 - 8.2e-75 250.7 0.8 1.5e-74 249.9 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAO83424.1 - 4.7e-60 202.9 0.0 6.2e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 GAO83424.1 - 0.098 11.9 0.2 8.5 5.5 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 GAO83425.1 - 3.5e-66 222.7 0.2 7.5e-66 221.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAO83425.1 - 1.5e-42 144.9 0.0 3.5e-42 143.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO83425.1 - 2.4e-06 27.6 0.1 1.1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAO83425.1 - 5.4e-06 26.1 0.1 3.2e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAO83425.1 - 8.2e-06 26.6 0.0 2.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO83425.1 - 4e-05 22.5 0.0 8.5e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 GAO83425.1 - 7.3e-05 22.9 0.5 0.0085 16.2 0.2 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAO83425.1 - 0.00034 19.7 0.0 0.0009 18.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 GAO83425.1 - 0.0011 18.3 1.5 0.077 12.3 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO83425.1 - 0.0013 18.6 0.0 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 GAO83425.1 - 0.0014 18.5 0.0 0.0067 16.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 GAO83425.1 - 0.0017 18.0 0.9 0.0043 16.7 0.2 2.0 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAO83425.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAO83425.1 - 0.006 15.7 0.2 0.017 14.2 0.1 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 GAO83425.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAO83425.1 - 0.0091 15.6 0.3 1.1 8.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 GAO83425.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 GAO83425.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAO83425.1 - 0.02 14.0 0.2 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAO83425.1 - 0.041 13.0 0.6 1.3 8.1 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 GAO83425.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTP_transferase PF00483.18 GAO83427.1 - 2.7e-48 164.4 0.0 5.6e-48 163.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 GAO83427.1 - 8.7e-13 47.1 8.1 1.1e-09 37.3 1.6 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAO83427.1 - 1.7e-10 41.2 0.0 2.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAO83427.1 - 8.5e-07 28.4 1.7 8.5e-07 28.4 1.2 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase SRP54 PF00448.17 GAO83427.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IspD PF01128.14 GAO83427.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 GAO83428.1 - 2.3e-07 30.9 0.4 1.1e-05 25.4 0.2 2.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO83428.1 - 0.0042 16.7 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 KR domain zf-H2C2_2 PF13465.1 GAO83429.1 - 2e-17 62.5 28.6 7e-07 29.2 1.4 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAO83429.1 - 7e-16 57.5 39.7 9.9e-05 22.4 3.6 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO83429.1 - 1.3e-05 25.1 36.4 0.022 15.0 3.0 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger EPTP PF03736.12 GAO83429.1 - 0.15 11.7 1.8 4.6 7.0 0.1 2.9 3 0 0 3 3 3 0 EPTP domain PAT1 PF09770.4 GAO83429.1 - 5.5 5.0 31.3 7.6 4.6 21.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suc_Fer-like PF06999.7 GAO83430.1 - 1.7e-34 119.8 0.0 3.3e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4129 PF13559.1 GAO83430.1 - 5.5e-05 23.0 0.1 0.00019 21.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Aminotran_1_2 PF00155.16 GAO83431.1 - 5.9e-36 124.1 0.0 7.7e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.1 GAO83432.1 - 8.3e-38 129.1 0.0 1.6e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 GAO83432.1 - 7.8e-33 113.8 1.6 1.3e-32 113.1 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 GAO83432.1 - 1e-32 112.0 0.0 2.2e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 GAO83432.1 - 1.6e-08 34.0 0.1 3.5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 GAO83432.1 - 0.0078 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 GAO83433.1 - 5.2e-42 140.2 8.7 1.4e-07 31.0 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 GAO83433.1 - 9.5e-14 50.8 0.8 1.8e-13 49.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO83433.1 - 3.8e-08 32.7 0.3 8e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 GAO83433.1 - 0.0087 14.2 1.1 0.54 8.3 0.2 2.9 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO83433.1 - 0.17 10.5 1.7 25 3.4 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like Uds1 PF15456.1 GAO83435.1 - 2.7e-47 159.7 4.8 2.7e-47 159.7 3.3 6.7 3 2 4 7 7 7 2 Up-regulated During Septation GrpE PF01025.14 GAO83435.1 - 0.0033 16.9 5.8 0.0033 16.9 4.0 7.4 2 1 4 6 6 6 2 GrpE DASH_Dam1 PF08653.5 GAO83435.1 - 0.26 11.0 3.2 6.4 6.6 0.1 4.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 MFS_1 PF07690.11 GAO83436.1 - 2e-25 89.3 33.8 2e-25 89.3 23.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAO83436.1 - 0.00015 20.3 3.0 0.00015 20.3 2.1 1.8 2 1 1 3 3 3 1 MFS/sugar transport protein Gate PF07670.9 GAO83436.1 - 7.1 6.5 11.8 2.3 8.1 3.5 3.2 2 2 0 2 2 2 0 Nucleoside recognition UCR_hinge PF02320.11 GAO83437.1 - 2.9e-22 78.3 5.7 2.9e-22 78.3 4.0 2.2 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Spore_coat_CotO PF14153.1 GAO83437.1 - 0.00028 20.4 11.0 0.0003 20.2 7.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 GAO83437.1 - 0.0057 15.3 4.1 0.0052 15.4 2.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CDC45 PF02724.9 GAO83437.1 - 0.01 13.9 9.7 0.0099 13.9 6.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Raftlin PF15250.1 GAO83437.1 - 0.028 12.9 4.8 0.038 12.5 3.3 1.2 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 GAO83437.1 - 0.048 11.3 6.2 0.044 11.4 4.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF2413 PF10310.4 GAO83437.1 - 0.25 10.0 16.9 0.34 9.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mpp10 PF04006.7 GAO83437.1 - 0.44 8.8 26.5 0.64 8.3 18.3 1.2 1 0 0 1 1 1 0 Mpp10 protein FancD2 PF14631.1 GAO83437.1 - 0.62 7.0 3.2 0.71 6.8 2.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1510 PF07423.6 GAO83437.1 - 0.94 8.7 26.1 1.4 8.2 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 GAO83437.1 - 2 8.4 18.7 3.1 7.7 13.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pex16 PF08610.5 GAO83437.1 - 3.2 6.6 6.7 4.4 6.1 4.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DDHD PF02862.12 GAO83437.1 - 3.2 7.4 13.7 4.7 6.9 9.5 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 GAO83437.1 - 4.9 6.9 21.6 7.4 6.3 15.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHW PF14286.1 GAO83437.1 - 5.4 6.2 12.3 7 5.8 8.5 1.1 1 0 0 1 1 1 0 DHHW protein Pox_Ag35 PF03286.9 GAO83437.1 - 6.4 6.2 16.7 16 4.9 11.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3c_N PF05470.7 GAO83437.1 - 9.6 4.1 15.4 13 3.7 10.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus WWbp PF10349.4 GAO83438.1 - 1.3e-25 90.5 0.8 1.8e-25 90.0 0.1 1.5 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 GAO83438.1 - 1.5e-05 24.6 0.0 0.00045 19.9 0.0 2.2 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 GAO83438.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.6 1 1 0 1 1 1 0 GRAM domain Acyltransferase PF01553.16 GAO83439.1 - 1.8e-05 24.2 0.0 0.00018 20.9 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Prenyltransf PF01255.14 GAO83440.1 - 1e-82 276.6 0.0 1.7e-82 275.9 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 GAO83441.1 - 1.3e-133 445.7 0.0 1.7e-133 445.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO83441.1 - 1.6e-08 34.7 0.1 2.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAO83441.1 - 1.4e-07 31.7 0.2 5.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 GAO83441.1 - 0.0053 16.9 0.2 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NmrA PF05368.8 GAO83441.1 - 0.0083 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAO83441.1 - 0.076 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aha1_N PF09229.6 GAO83442.1 - 8.2e-41 139.0 0.5 1.3e-40 138.3 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 GAO83442.1 - 8.7e-19 67.8 0.8 1.7e-18 66.8 0.5 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 GAO83442.1 - 0.0013 18.9 1.7 0.0046 17.1 1.1 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport FBPase PF00316.15 GAO83444.1 - 1e-118 395.8 0.0 1.2e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase V_ATPase_I PF01496.14 GAO83445.1 - 2.3e-297 988.0 0.4 2.3e-297 988.0 0.3 1.6 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family DUF3437 PF11919.3 GAO83445.1 - 9.7e-30 102.1 0.0 3.3e-29 100.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 GAO83445.1 - 0.00025 20.4 0.2 0.18 11.1 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 GAO83445.1 - 0.011 15.7 0.2 2.9 8.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat DUF1515 PF07439.6 GAO83445.1 - 0.015 15.0 0.7 0.067 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Adaptin_N PF01602.15 GAO83445.1 - 0.15 10.3 0.0 0.36 9.1 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region DUF3552 PF12072.3 GAO83445.1 - 0.9 8.7 5.5 33 3.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 GAO83445.1 - 3.1 6.6 3.3 2.3 7.0 0.2 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 GAO83445.1 - 6.3 6.6 7.1 4.5 7.0 0.2 2.8 3 0 0 3 3 3 0 Prefoldin subunit XRCC4 PF06632.7 GAO83446.1 - 0.14 10.9 0.4 0.3 9.8 0.3 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Aldo_ket_red PF00248.16 GAO83447.1 - 1.7e-67 227.2 0.0 2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 GAO83448.1 - 2.7e-72 242.6 0.0 4.7e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAO83448.1 - 6.4e-72 242.2 0.0 1.2e-71 241.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Pro_CA PF00484.14 GAO83448.1 - 2.2e-45 154.3 0.1 1e-44 152.2 0.0 2.1 2 0 0 2 2 2 1 Carbonic anhydrase Epimerase PF01370.16 GAO83448.1 - 3.4e-14 52.8 0.0 1.1e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO83448.1 - 9e-11 41.8 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO83448.1 - 4.5e-09 37.1 0.0 1.9e-08 35.1 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAO83448.1 - 1.1e-05 24.2 0.0 5.7e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO83448.1 - 0.00047 20.2 0.0 1.1 9.1 0.0 3.1 2 1 0 2 2 2 2 NADH(P)-binding RmlD_sub_bind PF04321.12 GAO83448.1 - 0.0028 16.5 0.0 0.053 12.4 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Ald_Xan_dh_C2 PF02738.13 GAO83450.1 - 1.5e-200 667.2 0.3 2e-200 666.7 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAO83450.1 - 1e-48 165.0 0.0 1.9e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 GAO83450.1 - 7e-34 116.2 0.0 1.5e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 GAO83450.1 - 2.3e-31 107.8 0.0 6.8e-31 106.2 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 GAO83450.1 - 1.6e-27 95.2 0.0 3.2e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 GAO83450.1 - 2.3e-08 33.6 1.0 5.5e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 GAO83450.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain YbaJ PF10757.4 GAO83451.1 - 0.021 14.9 2.1 0.14 12.3 0.1 2.9 2 1 1 3 3 3 0 Biofilm formation regulator YbaJ NSP2-B_epitope PF14757.1 GAO83451.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Peptidase_M56 PF05569.6 GAO83451.1 - 0.14 11.0 3.6 0.33 9.8 0.0 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 DUF1282 PF06930.7 GAO83451.1 - 0.15 11.7 3.8 0.098 12.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Ribosomal_L38e PF01781.13 GAO83452.1 - 0.11 12.2 0.1 0.38 10.5 0.1 1.9 1 1 1 2 2 2 0 Ribosomal L38e protein family zf-MYND PF01753.13 GAO83452.1 - 5.9 6.8 13.2 15 5.5 9.2 1.7 1 0 0 1 1 1 0 MYND finger Aminotran_1_2 PF00155.16 GAO83453.1 - 9.8e-71 238.5 0.0 1.1e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO83453.1 - 0.0004 19.5 0.0 0.0011 18.0 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAO83453.1 - 0.00055 19.1 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAO83453.1 - 0.0013 17.1 0.0 0.0019 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO83453.1 - 0.042 12.5 0.0 0.13 10.9 0.0 1.8 1 1 0 1 1 1 0 Aminotransferase class-V T_hemolysin PF12261.3 GAO83453.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin MgsA_C PF12002.3 GAO83454.1 - 2.8e-57 193.0 0.5 4.6e-57 192.3 0.0 1.6 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAO83454.1 - 1.2e-13 51.4 0.0 2.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO83454.1 - 8.9e-11 41.2 0.0 3.8e-10 39.2 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAO83454.1 - 1.7e-05 24.5 0.0 0.00014 21.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAO83454.1 - 3.3e-05 23.4 0.1 0.0013 18.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAO83454.1 - 8e-05 21.8 0.0 0.15 11.2 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAO83454.1 - 0.00016 21.3 0.0 0.0022 17.5 0.0 2.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO83454.1 - 0.00057 20.0 0.1 0.0021 18.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO83454.1 - 0.00076 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAO83454.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO83454.1 - 0.003 17.5 0.1 0.052 13.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 GAO83454.1 - 0.0033 16.4 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 GAO83454.1 - 0.0053 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 GAO83454.1 - 0.01 14.6 0.1 0.028 13.1 0.1 1.7 1 1 1 2 2 2 0 TIP49 C-terminus AAA_17 PF13207.1 GAO83454.1 - 0.016 16.0 0.0 0.064 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO83454.1 - 0.017 14.7 0.1 0.038 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 GAO83454.1 - 0.019 14.7 0.1 6 6.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 GAO83454.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF927 PF06048.6 GAO83454.1 - 0.039 13.2 0.1 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_18 PF13238.1 GAO83454.1 - 0.069 13.4 0.1 0.2 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain SKI PF01202.17 GAO83454.1 - 0.085 12.7 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 GAO83454.1 - 0.095 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 GAO83454.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF605 PF04652.11 GAO83454.1 - 0.16 11.3 7.7 0.24 10.7 5.3 1.1 1 0 0 1 1 1 0 Vta1 like Parvo_NS1 PF01057.12 GAO83454.1 - 0.22 10.3 0.0 0.79 8.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PRP21_like_P PF12230.3 GAO83454.1 - 2.9 7.3 5.1 0.52 9.7 0.1 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein EF-hand_1 PF00036.27 GAO83456.1 - 1.9e-15 54.8 2.5 5.3e-05 22.2 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAO83456.1 - 2.7e-14 53.0 4.6 1e-08 35.1 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAO83456.1 - 7.8e-14 50.2 6.2 6.4e-06 25.6 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 GAO83456.1 - 4.7e-11 42.1 2.5 9.9e-09 34.6 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 GAO83456.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 GAO83456.1 - 0.13 11.6 10.6 0.61 9.5 0.1 3.7 4 0 0 4 4 4 0 EF hand Ank_2 PF12796.2 GAO83457.1 - 1.2e-40 137.7 5.5 2.1e-18 66.4 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83457.1 - 1e-29 100.7 10.4 9.7e-08 31.4 0.0 7.4 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAO83457.1 - 6.8e-29 99.7 2.9 8.3e-09 35.7 0.0 4.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83457.1 - 2.7e-25 85.9 2.9 0.00011 22.0 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 GAO83457.1 - 1.8e-24 85.1 3.0 2.3e-06 27.6 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Asp_protease_2 PF13650.1 GAO83457.1 - 0.06 13.8 1.0 4.8 7.7 0.0 3.0 2 1 1 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 GAO83457.1 - 0.066 13.0 2.0 0.44 10.4 0.0 3.0 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAO83457.1 - 0.081 12.8 1.0 7.8 6.4 0.0 3.0 2 1 1 3 3 3 0 Retroviral aspartyl protease F-box PF00646.28 GAO83457.1 - 0.16 11.6 0.1 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Reprolysin_5 PF13688.1 GAO83458.1 - 3.2e-63 213.2 5.9 3.2e-63 213.2 4.1 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAO83458.1 - 1.6e-49 168.2 2.2 3.4e-49 167.2 1.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAO83458.1 - 1e-48 165.5 0.9 2e-48 164.6 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like IMS PF00817.15 GAO83458.1 - 2.3e-37 128.0 0.0 6.1e-37 126.7 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family Reprolysin_3 PF13582.1 GAO83458.1 - 5.5e-21 75.3 0.6 1.8e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 GAO83458.1 - 2.1e-20 72.6 33.3 2.1e-20 72.6 23.1 4.3 2 1 2 4 4 4 1 Disintegrin IMS_C PF11799.3 GAO83458.1 - 4.8e-10 39.4 0.1 3.7e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAO83458.1 - 0.00046 20.0 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif Pep_M12B_propep PF01562.14 GAO83458.1 - 0.0084 15.9 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide C2 PF00168.25 GAO83460.1 - 5.1e-21 74.3 0.0 1.1e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF3332 PF11810.3 GAO83460.1 - 1.3 8.6 2.6 3.5 7.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) DUF2890 PF11081.3 GAO83460.1 - 5.8 6.9 18.7 0.37 10.8 6.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Na_trans_assoc PF06512.8 GAO83460.1 - 9.7 6.0 14.6 10 5.9 1.2 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated GET2 PF08690.5 GAO83461.1 - 3.5e-08 33.0 0.0 7.8e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 AMP-binding PF00501.23 GAO83462.1 - 4.2e-91 305.4 0.1 5.9e-91 304.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO83462.1 - 4.3e-21 75.6 6.4 3.7e-20 72.6 0.4 3.6 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Nup96 PF12110.3 GAO83463.1 - 1.8e-106 355.5 0.7 3.2e-106 354.6 0.5 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 GAO83463.1 - 1.7e-48 164.0 0.0 2.7e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase MFS_1 PF07690.11 GAO83463.1 - 1.8e-44 151.9 22.5 1.8e-44 151.9 15.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Nucleoporin_FG PF13634.1 GAO83463.1 - 6.7e-10 39.1 185.0 8.9e-06 25.9 39.7 9.9 3 2 5 8 8 8 3 Nucleoporin FG repeat region 7TM_GPCR_Srz PF10325.4 GAO83463.1 - 0.37 9.8 0.2 0.71 8.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Complex1_51K PF01512.12 GAO83464.1 - 5.9e-46 155.9 0.0 1e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 GAO83464.1 - 2.9e-18 64.7 1.3 6e-18 63.7 0.9 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 GAO83464.1 - 1.3e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SLBB domain SET PF00856.23 GAO83464.1 - 0.0019 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 SET domain SAPS PF04499.10 GAO83465.1 - 2.4e-215 715.6 1.8 7.1e-215 714.1 0.0 2.6 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Snf7 PF03357.16 GAO83466.1 - 1.1e-42 145.3 16.9 1.3e-42 145.0 11.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 GAO83466.1 - 0.00038 19.9 6.9 0.00038 19.9 4.8 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 GAO83466.1 - 0.0083 16.3 8.7 0.061 13.5 0.5 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAO83466.1 - 0.0085 15.3 2.9 0.035 13.2 0.3 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Zwint PF15556.1 GAO83466.1 - 0.011 15.0 4.3 0.014 14.6 3.0 1.3 1 0 0 1 1 1 0 ZW10 interactor DUF1395 PF07160.7 GAO83466.1 - 0.017 14.6 5.9 0.06 12.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Alpha-2-MRAP_C PF06401.6 GAO83466.1 - 0.037 13.8 1.7 0.051 13.4 0.6 1.6 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3584 PF12128.3 GAO83466.1 - 0.056 10.7 8.5 0.075 10.3 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HHH_2 PF12826.2 GAO83466.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Atg14 PF10186.4 GAO83466.1 - 0.092 11.6 7.7 0.12 11.3 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec34 PF04136.10 GAO83466.1 - 0.13 11.9 4.9 1.7 8.3 1.7 2.1 1 1 1 2 2 2 0 Sec34-like family Mnd1 PF03962.10 GAO83466.1 - 0.15 11.6 9.6 0.57 9.8 6.6 1.8 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 GAO83466.1 - 0.17 11.4 4.3 0.84 9.1 0.4 2.2 1 1 0 2 2 2 0 IncA protein Prefoldin PF02996.12 GAO83466.1 - 0.55 9.8 9.2 1.4 8.5 0.0 3.7 2 1 2 4 4 4 0 Prefoldin subunit CDC37_N PF03234.9 GAO83466.1 - 0.76 10.0 9.3 1 9.6 6.3 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 GAO83466.1 - 0.79 8.0 8.4 1.6 7.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mod_r PF07200.8 GAO83466.1 - 0.81 9.5 8.7 0.17 11.7 2.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 GAO83466.1 - 0.93 9.6 9.0 5.2 7.2 1.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 GAO83466.1 - 1 9.8 0.0 1 9.8 0.0 3.2 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 GAO83466.1 - 1.2 9.1 13.3 1 9.2 6.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.1 GAO83466.1 - 1.3 8.9 10.3 0.52 10.2 5.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Cortex-I_coil PF09304.5 GAO83466.1 - 1.9 8.5 8.2 4.6 7.3 4.7 2.2 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF4337 PF14235.1 GAO83466.1 - 2.2 8.1 8.8 0.21 11.4 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) APG6 PF04111.7 GAO83466.1 - 7.3 5.5 10.5 3.8 6.4 1.1 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Nramp PF01566.13 GAO83467.1 - 7.9e-93 311.0 15.9 7.9e-93 311.0 11.0 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Drf_GBD PF06371.8 GAO83468.1 - 6.1e-19 68.1 1.0 1.3e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAO83468.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Diaphanous FH3 Domain Thiolase_N PF00108.18 GAO83470.1 - 9.3e-78 260.8 1.8 9.3e-78 260.8 1.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO83470.1 - 2.7e-43 146.2 0.4 5.6e-43 145.2 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAO83470.1 - 0.02 14.3 1.6 0.11 12.0 0.6 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 GAO83470.1 - 0.034 14.1 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAO83470.1 - 0.07 12.7 0.4 16 5.2 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_6 PF03737.10 GAO83471.1 - 2.5e-11 43.6 0.7 1.4e-09 37.9 0.5 2.2 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Acetyltransf_2 PF00797.12 GAO83472.1 - 3.4e-42 144.6 0.0 4.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase MOZ_SAS PF01853.13 GAO83473.1 - 2.8e-79 264.7 0.0 4.2e-79 264.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 GAO83473.1 - 0.0016 18.0 8.2 0.0016 18.0 5.7 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 GAO83473.1 - 0.065 12.5 2.1 0.16 11.3 1.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-MIZ PF02891.15 GAO83473.1 - 0.11 12.0 2.4 0.24 10.9 1.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Zn-ribbon_8 PF09723.5 GAO83473.1 - 6.3 6.8 7.8 2.7 8.0 0.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Velvet PF11754.3 GAO83474.1 - 7.1e-60 202.0 1.8 4.4e-59 199.5 1.2 2.1 1 1 0 1 1 1 1 Velvet factor TFIIA PF03153.8 GAO83474.1 - 1.4 8.7 11.8 2 8.2 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_17 PF13207.1 GAO83476.1 - 4.4e-07 30.7 0.0 5.5e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 GAO83476.1 - 2.1e-05 24.8 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 GAO83476.1 - 0.00012 22.3 0.0 0.00021 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAO83476.1 - 0.00076 19.0 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 GAO83476.1 - 0.0098 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_21 PF13304.1 GAO83476.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 GAO83476.1 - 0.017 14.7 0.1 0.054 13.1 0.0 1.8 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAO83476.1 - 0.019 14.9 0.0 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO83476.1 - 0.048 13.5 0.0 0.082 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO83476.1 - 0.05 13.5 0.1 0.093 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 GAO83476.1 - 0.062 12.1 0.4 0.18 10.6 0.3 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein SNF2_N PF00176.18 GAO83477.1 - 1.4e-33 116.0 0.0 2.5e-30 105.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO83477.1 - 0.00031 20.5 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box PF00505.14 GAO83478.1 - 5.8e-23 80.9 1.2 1.1e-22 80.1 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAO83478.1 - 2e-08 34.4 0.5 3.8e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain Lipase_GDSL PF00657.17 GAO83479.1 - 2e-07 31.0 0.3 2.6e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3365 PF11845.3 GAO83479.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Ribosomal_S6e PF01092.14 GAO83480.1 - 3.9e-58 194.5 0.0 8.5e-58 193.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 GAO83481.1 - 7.4e-46 154.6 0.8 2.5e-44 149.7 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAO83481.1 - 2.9e-43 147.7 2.4 4.3e-36 124.3 1.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAO83481.1 - 8.8e-14 51.3 0.5 5e-13 48.8 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAO83481.1 - 1.5e-05 24.3 0.3 2.9e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 GAO83481.1 - 0.41 10.3 2.5 0.74 9.5 1.7 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF913 PF06025.7 GAO83482.1 - 8.7e-171 567.7 0.0 8.7e-171 567.7 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 GAO83482.1 - 2.1e-104 349.3 0.2 2.1e-104 349.3 0.2 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.20 GAO83482.1 - 7.4e-97 324.3 0.0 1.2e-96 323.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 GAO83482.1 - 2.5e-33 114.2 10.9 2.5e-33 114.2 7.6 4.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 GAO83482.1 - 0.005 16.6 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain An_peroxidase PF03098.10 GAO83483.1 - 1.7e-100 336.9 0.0 2.4e-98 329.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAO83483.1 - 9.3e-08 31.0 0.0 1.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.11 GAO83484.1 - 1.5e-32 112.4 0.4 2.1e-32 111.9 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAO83484.1 - 0.00014 21.8 0.2 0.00037 20.5 0.1 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAO83484.1 - 0.0006 19.1 0.2 0.00079 18.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_transf_34 PF05637.7 GAO83485.1 - 8.4e-66 221.8 0.0 1.1e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 GAO83485.1 - 0.021 14.1 0.0 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Ribosomal_L28 PF00830.14 GAO83486.1 - 7.2e-20 70.5 0.7 1.3e-19 69.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.8 GAO83487.1 - 3.6e-187 621.9 0.0 4.1e-187 621.7 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 GAO83487.1 - 5.9e-11 41.8 0.7 1.3e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 GAO83487.1 - 1.2e-10 41.7 0.2 1e-06 28.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO83487.1 - 2.3e-05 24.5 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO83487.1 - 2.3e-05 24.4 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 GAO83487.1 - 0.0002 21.0 0.1 0.00048 19.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAO83487.1 - 0.00022 21.2 0.1 0.00048 20.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO83487.1 - 0.0014 18.3 0.1 0.37 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAO83487.1 - 0.0032 16.9 0.1 2.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 GAO83487.1 - 0.0037 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAO83487.1 - 0.004 16.2 0.3 0.0089 15.1 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 GAO83487.1 - 0.013 14.7 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAO83487.1 - 0.02 15.1 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAO83487.1 - 0.029 13.8 0.1 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 GAO83487.1 - 0.042 12.8 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 GAO83487.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 GAO83487.1 - 0.067 14.0 0.0 0.17 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain V-SNARE PF05008.10 GAO83489.1 - 2.4e-22 78.8 8.2 2.4e-22 78.8 5.7 2.5 2 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAO83489.1 - 1.1e-16 60.6 4.6 1.1e-16 60.6 3.2 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1978 PF09321.5 GAO83489.1 - 0.021 14.2 10.4 0.027 13.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF825 PF05695.7 GAO83489.1 - 0.044 11.1 0.7 0.049 11.0 0.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) DUF1474 PF07342.6 GAO83489.1 - 0.085 13.0 0.1 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) TMP_2 PF06791.8 GAO83489.1 - 0.56 9.7 3.9 2.3 7.7 0.6 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein Sec20 PF03908.8 GAO83489.1 - 0.75 9.5 4.2 0.54 9.9 0.2 2.5 2 2 0 2 2 2 0 Sec20 YtxH PF12732.2 GAO83489.1 - 1 9.7 4.2 2.2 8.7 2.8 2.0 1 1 0 1 1 1 0 YtxH-like protein Histone_HNS PF00816.16 GAO83489.1 - 1.2 9.6 8.0 0.094 13.2 1.4 2.0 2 0 0 2 2 2 0 H-NS histone family MbeB_N PF04837.7 GAO83489.1 - 2.1 8.5 6.3 0.31 11.1 0.5 2.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Exonuc_VII_L PF02601.10 GAO83489.1 - 2.4 7.2 11.9 4.1 6.5 8.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.6 GAO83489.1 - 9.2 4.8 13.7 2 7.0 4.7 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2407_C PF13373.1 GAO83490.1 - 1.9e-44 150.9 0.2 3.1e-44 150.2 0.2 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 GAO83490.1 - 3.7e-33 113.5 0.0 9.1e-33 112.3 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 GAO83490.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Fe-S_biosyn PF01521.15 GAO83491.1 - 5.3e-16 58.5 0.0 7.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 GAO83491.1 - 0.64 9.3 9.9 0.92 8.8 6.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF1741 PF08427.5 GAO83492.1 - 1.6e-95 319.1 0.0 7.3e-95 316.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) UPF0118 PF01594.11 GAO83492.1 - 0.13 11.2 0.5 0.22 10.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 MRG PF05712.8 GAO83493.1 - 1e-56 190.9 0.2 1.7e-56 190.2 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 GAO83493.1 - 8.8e-10 38.1 2.6 2e-09 37.0 1.8 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 GAO83493.1 - 0.00017 21.1 1.1 0.00053 19.6 0.8 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 GAO83493.1 - 0.029 14.5 0.2 0.084 13.0 0.1 1.7 1 0 0 1 1 1 0 PWWP domain Cnl2_NKP2 PF09447.5 GAO83494.1 - 5.3e-29 99.6 1.6 5.3e-29 99.6 1.1 1.6 2 0 0 2 2 2 1 Cnl2/NKP2 family protein AAA_13 PF13166.1 GAO83494.1 - 0.012 14.1 0.1 0.014 13.8 0.1 1.0 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 GAO83494.1 - 0.02 14.0 0.2 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Rabaptin PF03528.10 GAO83494.1 - 0.035 14.0 0.8 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Rabaptin COG2 PF06148.6 GAO83494.1 - 0.049 13.5 0.3 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CPDase PF07823.6 GAO83494.1 - 0.052 13.0 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein CENP-F_leu_zip PF10473.4 GAO83494.1 - 0.054 13.3 1.7 0.13 12.0 1.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 GAO83494.1 - 0.06 12.9 0.3 0.32 10.5 0.2 2.0 1 1 0 1 1 1 0 IncA protein Sec34 PF04136.10 GAO83494.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Sec34-like family YfcL PF08891.6 GAO83494.1 - 0.089 12.7 0.7 5.2 7.1 0.1 2.4 2 0 0 2 2 2 0 YfcL protein DUF724 PF05266.9 GAO83494.1 - 0.25 10.9 4.4 1 8.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 GAO83494.1 - 0.49 10.3 2.3 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ctf8 PF09696.5 GAO83496.1 - 2.7e-40 136.9 0.0 3.1e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 GAO83497.1 - 1.6e-21 76.5 0.7 1.5e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAO83497.1 - 5.5e-14 52.0 0.1 1.4e-05 25.0 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAO83497.1 - 8.6e-08 32.2 0.2 0.0063 16.4 0.1 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.2 GAO83497.1 - 9.8e-07 29.3 0.0 0.011 16.3 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAO83497.1 - 1.4e-06 28.3 0.0 0.0035 17.2 0.0 3.2 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Dabb PF07876.7 GAO83498.1 - 2.3e-11 43.9 0.0 2.6e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RabGAP-TBC PF00566.13 GAO83499.1 - 1.2e-51 175.1 0.2 1.4e-50 171.7 0.2 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PPTA PF01239.17 GAO83499.1 - 1.1e-34 116.3 12.8 5.8e-08 31.7 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.27 GAO83500.1 - 1.2e-14 53.4 11.9 2e-06 27.4 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Utp12 PF04003.7 GAO83502.1 - 7.7e-21 74.0 0.1 1.3e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 GAO83503.1 - 6.6e-42 141.3 0.7 6.2e-20 70.9 0.1 2.8 2 0 0 2 2 2 2 Bromodomain DUF3573 PF12097.3 GAO83503.1 - 1 7.9 4.0 1.6 7.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PARP PF00644.15 GAO83503.1 - 4.1 6.7 12.0 0.41 10.0 3.7 2.7 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain zf-CSL PF05207.8 GAO83504.1 - 1.4e-23 82.1 0.6 2.4e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger HAUS4 PF14735.1 GAO83504.1 - 8.6e-06 25.2 3.1 1.5e-05 24.4 2.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 Zn-ribbon_8 PF09723.5 GAO83504.1 - 0.12 12.3 0.2 0.35 10.8 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Frataxin_Cyay PF01491.11 GAO83505.1 - 9.9e-31 105.7 0.1 5.9e-30 103.2 0.1 1.9 1 1 0 1 1 1 1 Frataxin-like domain AKAP7_NLS PF10469.4 GAO83506.1 - 2.5e-15 56.7 0.0 6.6e-14 52.1 0.0 2.8 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 GAO83507.1 - 1.6e-176 587.7 5.5 1.6e-176 587.7 3.8 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF1768 PF08719.6 GAO83507.1 - 0.009 15.7 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) Vps53_N PF04100.7 GAO83507.1 - 0.24 10.1 11.1 0.062 12.0 1.7 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.15 GAO83508.1 - 3.1e-15 55.4 0.3 4e-15 55.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 GAO83509.1 - 4e-22 78.1 0.0 6.5e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAO83509.1 - 1.4e-08 33.9 0.0 5.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAO83509.1 - 3.3e-06 26.3 0.0 5.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO83509.1 - 5.7e-06 25.6 0.0 9.1e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAO83509.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_15 PF12324.3 GAO83509.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase SLA_LP_auto_ag PF05889.8 GAO83509.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cys_Met_Meta_PP PF01053.15 GAO83509.1 - 0.17 10.1 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HMGL-like PF00682.14 GAO83510.1 - 2e-71 240.4 0.4 2.9e-71 239.8 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Lumazine_bd PF12870.2 GAO83510.1 - 0.068 13.2 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 Lumazine-binding domain DUF4448 PF14610.1 GAO83511.1 - 2.5e-44 151.0 0.0 3.2e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PTH2 PF01981.11 GAO83513.1 - 1.2e-43 147.4 0.3 1.6e-43 147.0 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3245 PF11595.3 GAO83513.1 - 1.9 8.7 5.7 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) SART-1 PF03343.8 GAO83514.1 - 9.6e-188 625.3 67.0 1.1e-187 625.1 46.4 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.16 GAO83515.1 - 6.2e-93 311.6 0.0 7.1e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF155 PF02582.9 GAO83517.1 - 6e-59 198.8 0.0 8.9e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-C2H2 PF00096.21 GAO83518.1 - 5.5e-20 70.4 26.4 2.6e-05 24.3 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO83518.1 - 1e-19 69.7 30.9 2.9e-07 30.4 0.9 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO83518.1 - 2.7e-13 49.2 25.6 0.00047 20.2 3.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO83518.1 - 4.1e-05 23.5 6.5 0.76 9.9 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO83518.1 - 0.011 15.8 14.7 0.23 11.7 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAO83518.1 - 0.032 14.1 17.4 1.6 8.7 0.9 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 GAO83518.1 - 0.087 12.5 0.3 0.087 12.5 0.2 2.9 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 GAO83518.1 - 0.13 12.2 9.7 10 6.1 0.1 3.8 3 1 1 4 4 4 0 Zinc ribbon domain DUF2072 PF09845.4 GAO83518.1 - 0.27 11.1 1.1 0.6 10.0 0.8 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) C1_1 PF00130.17 GAO83518.1 - 0.46 10.2 6.5 0.92 9.2 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.9 GAO83518.1 - 1.3 8.7 4.3 15 5.3 0.1 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.1 GAO83518.1 - 2.1 8.1 11.1 2.3 7.9 0.4 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HNH PF01844.18 GAO83518.1 - 7.3 6.5 6.7 21 5.0 0.1 3.5 4 0 0 4 4 4 0 HNH endonuclease Fer4_18 PF13746.1 GAO83518.1 - 9 6.8 7.6 5.7 7.4 0.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Methyltransf_23 PF13489.1 GAO83519.1 - 8.9e-20 71.0 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO83519.1 - 9.9e-13 48.4 0.0 1.7e-11 44.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83519.1 - 6e-11 42.7 0.0 1.5e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO83519.1 - 7.8e-11 42.5 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83519.1 - 9.1e-09 35.0 0.0 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 GAO83519.1 - 7e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83519.1 - 5.3e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAO83519.1 - 0.0053 17.5 0.0 0.0095 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.10 GAO83519.1 - 0.1 12.4 0.2 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain KRBA1 PF15287.1 GAO83519.1 - 0.37 10.1 0.1 0.37 10.1 0.0 2.9 4 0 0 4 4 4 0 KRBA1 family repeat BRAP2 PF07576.7 GAO83520.1 - 2.6e-27 94.5 0.1 4.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 GAO83520.1 - 7.5e-21 74.0 3.3 2.1e-20 72.5 2.3 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAO83520.1 - 2e-09 37.1 9.9 2e-09 37.1 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 GAO83520.1 - 0.00012 21.7 7.5 0.00012 21.7 5.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO83520.1 - 0.00048 19.7 8.5 0.00048 19.7 5.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO83520.1 - 0.00054 19.5 5.3 0.00054 19.5 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO83520.1 - 0.001 19.0 9.3 0.001 19.0 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO83520.1 - 0.0013 18.4 4.3 0.0039 16.8 1.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAO83520.1 - 0.0022 18.0 5.5 0.0022 18.0 3.8 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 GAO83520.1 - 0.0093 15.7 2.9 0.0093 15.7 2.0 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein V_ATPase_I PF01496.14 GAO83520.1 - 0.015 13.2 4.3 0.022 12.6 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 GAO83520.1 - 0.041 13.6 16.7 0.076 12.7 11.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 GAO83520.1 - 0.11 11.9 12.4 0.17 11.3 8.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.10 GAO83520.1 - 0.34 10.0 7.8 0.68 9.0 5.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.1 GAO83520.1 - 0.61 9.2 12.6 0.93 8.6 8.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PIN_2 PF10130.4 GAO83520.1 - 0.84 9.6 4.6 12 5.9 0.0 2.7 2 1 0 2 2 2 0 PIN domain DUF4200 PF13863.1 GAO83520.1 - 1.1 9.2 20.6 0.43 10.5 6.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-Apc11 PF12861.2 GAO83520.1 - 1.9 8.3 13.5 0.023 14.5 3.7 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 GAO83520.1 - 3.8 7.1 8.6 1e+02 2.5 6.0 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.6 GAO83520.1 - 9.6 6.0 7.8 0.47 10.2 0.9 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain ubiquitin PF00240.18 GAO83521.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 GAO83521.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAO83521.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAO83521.1 - 9.7e-17 61.1 0.4 0.00058 19.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAO83521.1 - 6.8e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAO83521.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAO83521.1 - 5.4e-08 32.7 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 GAO83521.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 GAO83521.1 - 0.00019 21.0 0.4 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 GAO83521.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 GAO83521.1 - 0.00085 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 GAO83521.1 - 0.00086 18.4 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.1 GAO83521.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 GAO83521.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 GAO83521.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 GAO83521.1 - 0.034 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 GAO83521.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 GAO83521.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 GAO83521.1 - 0.06 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 GAO83521.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 GAO83521.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 GAO83521.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 GAO83521.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Zn_clus PF00172.13 GAO83522.1 - 0.0026 17.6 7.7 0.0058 16.5 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 GAO83522.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein CAF-1_p150 PF11600.3 GAO83522.1 - 0.79 9.0 9.2 1.4 8.2 6.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF566 PF04484.7 GAO83522.1 - 4.6 6.6 9.0 7.8 5.9 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF607 PF04678.8 GAO83523.1 - 2.2e-46 158.0 0.0 4.7e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Prenyltrans PF00432.16 GAO83523.1 - 8.9e-38 127.5 31.0 8.5e-10 38.0 1.5 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAO83523.1 - 3e-23 82.3 0.0 3.1e-16 59.7 0.0 4.3 2 1 2 4 4 4 3 Prenyltransferase-like dsrm PF00035.20 GAO83523.1 - 0.002 18.6 0.0 0.0066 16.9 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Hpt PF01627.18 GAO83525.1 - 5e-12 45.6 0.0 8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Cauli_AT PF03233.8 GAO83525.1 - 0.28 10.8 3.5 1.2 8.8 2.5 1.9 1 1 0 1 1 1 0 Aphid transmission protein PTPLA PF04387.9 GAO83526.1 - 7.4e-59 197.8 0.6 1.2e-58 197.1 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 GAO83527.1 - 5.1e-21 75.3 3.6 3.7e-20 72.6 2.1 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.17 GAO83527.1 - 1.3e-12 47.0 0.5 2.6e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 LSM domain Tom22 PF04281.8 GAO83527.1 - 0.064 12.7 0.4 0.064 12.7 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PGP_phosphatase PF09419.5 GAO83528.1 - 9.8e-66 220.2 0.0 1.2e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 GAO83528.1 - 6.2e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Homeobox PF00046.24 GAO83529.1 - 9.2e-20 70.0 4.3 2.2e-19 68.8 3.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAO83529.1 - 0.00023 20.8 0.6 0.0007 19.2 0.4 1.9 1 0 0 1 1 1 1 Homeobox KN domain CAF-1_p150 PF11600.3 GAO83529.1 - 1.3 8.3 6.4 2 7.7 4.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal E1-E2_ATPase PF00122.15 GAO83530.1 - 6.6e-22 77.6 0.1 6.6e-22 77.6 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAO83530.1 - 8.5e-17 62.2 0.0 1.4e-15 58.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO83530.1 - 2.5e-14 53.8 0.1 3.1e-13 50.3 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO83530.1 - 1e-10 41.4 0.0 3.7e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO83530.1 - 0.00013 21.6 0.1 0.00038 20.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Vac_Fusion PF02346.11 GAO83530.1 - 0.032 13.6 0.1 0.12 11.8 0.1 2.0 1 0 0 1 1 1 0 Chordopoxvirus fusion protein vWA-TerF-like PF10138.4 GAO83531.1 - 0.0045 16.8 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus GFO_IDH_MocA PF01408.17 GAO83532.1 - 1.1e-12 48.4 0.1 2.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAO83532.1 - 0.0013 19.0 0.1 0.0032 17.8 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 GAO83532.1 - 0.0094 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain SRP72 PF08492.7 GAO83533.1 - 5.8e-19 68.2 1.8 5.8e-19 68.2 1.2 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 GAO83533.1 - 1.8e-06 28.1 10.1 0.18 12.1 0.0 4.9 4 2 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO83533.1 - 3.9e-06 26.9 8.4 0.0045 17.0 0.6 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAO83533.1 - 9.4e-05 22.7 14.4 2.8 8.8 0.0 7.7 6 3 2 8 8 8 2 Tetratricopeptide repeat PPR PF01535.15 GAO83533.1 - 0.00076 19.2 0.0 7.2 6.8 0.0 4.5 4 0 0 4 4 4 1 PPR repeat TPR_2 PF07719.12 GAO83533.1 - 0.0096 15.7 8.7 3.6 7.7 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO83533.1 - 0.84 10.2 9.0 11 6.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83533.1 - 7.6 7.3 24.5 0.24 12.0 0.3 6.1 5 1 2 7 7 7 0 Tetratricopeptide repeat Fringe PF02434.11 GAO83534.1 - 4.2e-11 42.5 0.1 2.5e-10 39.9 0.0 2.2 1 1 1 2 2 2 1 Fringe-like DUF604 PF04646.7 GAO83534.1 - 4.5e-07 29.3 0.0 8.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fungal_trans PF04082.13 GAO83535.1 - 4.6e-22 78.1 0.1 7e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83535.1 - 1.4e-08 34.5 11.5 2.8e-08 33.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 GAO83536.1 - 8e-162 539.0 3.0 1e-161 538.7 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO83536.1 - 0.0018 18.0 1.8 0.0033 17.2 0.2 2.3 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_15 PF00723.16 GAO83537.1 - 6.2e-100 334.8 0.0 1.2e-99 333.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAO83537.1 - 6.3e-28 96.2 0.0 1.5e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.19 GAO83538.1 - 6.7e-70 235.9 0.3 9.1e-70 235.5 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO83538.1 - 2.7e-33 113.8 0.4 8.3e-33 112.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 GAO83538.1 - 0.021 12.6 0.1 0.047 11.4 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Homeobox_KN PF05920.6 GAO83540.1 - 2.8e-20 71.7 0.4 6e-20 70.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAO83540.1 - 3e-07 29.9 0.1 6.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 GAO83541.1 - 3.5e-45 154.1 0.0 5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAO83541.1 - 1.9e-09 38.0 0.0 3.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.1 GAO83542.1 - 4.3e-51 173.7 47.6 5.6e-51 173.4 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO83542.1 - 1.9e-22 79.2 44.9 3.5e-22 78.3 19.3 2.0 2 0 0 2 2 2 2 Amino acid permease Glyco_hydro_47 PF01532.15 GAO83544.1 - 6.1e-183 608.5 0.2 7e-183 608.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med20 PF08612.6 GAO83545.1 - 2.1e-100 334.4 0.0 2.4e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex TOBE_2 PF08402.5 GAO83545.1 - 0.055 13.4 0.2 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 TOBE domain EF-hand_1 PF00036.27 GAO83546.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAO83546.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAO83546.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 GAO83546.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAO83546.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAO83546.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAO83546.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAO83546.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 GAO83546.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAO83546.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 GAO83546.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 GAO83546.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 GAO83546.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 GAO83546.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 GAO83546.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 GAO83546.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 GAO83546.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 GAO83546.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 GAO83546.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 GAO83547.1 - 6.9e-17 60.9 3.0 6.9e-17 60.9 2.1 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAO83547.1 - 3.4e-12 46.4 4.2 9.3e-12 45.0 0.1 2.4 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 GAO83547.1 - 0.016 15.2 11.8 0.02 14.8 0.1 3.6 2 2 1 3 3 3 0 Syntaxin-like protein DUF2019 PF09450.5 GAO83547.1 - 0.041 13.7 1.0 0.085 12.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) MCPsignal PF00015.16 GAO83547.1 - 0.092 12.2 10.1 0.024 14.1 1.6 2.5 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 GAO83547.1 - 0.32 10.8 3.6 3.9 7.4 0.0 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.6 GAO83547.1 - 0.53 10.0 10.4 0.64 9.8 1.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DNA_repr_REX1B PF14966.1 GAO83547.1 - 0.68 10.3 3.5 1.6 9.1 0.0 3.1 3 1 1 4 4 4 0 DNA repair REX1-B CTD_bind PF04818.8 GAO83548.1 - 7.4e-21 74.1 0.3 1.4e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 GAO83548.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) MxiH PF09392.5 GAO83548.1 - 0.16 12.5 3.5 9.7 6.8 1.1 3.2 2 1 0 2 2 2 0 Type III secretion needle MxiH like Clathrin_lg_ch PF01086.12 GAO83549.1 - 2.2e-80 269.8 1.2 2.5e-80 269.6 0.9 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 GAO83550.1 - 7.6e-62 208.7 1.5 7.6e-62 208.7 1.0 2.9 3 2 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 GAO83550.1 - 5.1e-52 175.8 1.1 1.2e-51 174.6 0.8 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 GAO83550.1 - 4.1e-28 97.1 2.6 7.6e-28 96.2 0.6 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.18 GAO83551.1 - 1.3e-45 156.0 10.1 1.6e-45 155.6 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAO83551.1 - 5e-36 124.0 0.0 1.6e-35 122.4 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 GAO83551.1 - 6.8e-05 22.9 0.1 0.22 11.4 0.1 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAO83551.1 - 8.9e-05 21.8 0.1 0.0036 16.5 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAO83551.1 - 0.0018 17.7 0.0 0.0054 16.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO83551.1 - 0.0057 17.4 0.0 0.014 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO83551.1 - 0.0066 16.4 0.2 0.025 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 GAO83551.1 - 0.013 14.9 0.2 0.18 11.2 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.1 GAO83551.1 - 0.017 15.2 0.2 0.1 12.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO83551.1 - 0.017 14.6 0.0 0.063 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAO83551.1 - 0.024 14.8 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAO83551.1 - 0.025 13.9 0.4 0.17 11.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 GAO83551.1 - 0.034 12.7 0.2 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 GAO83551.1 - 0.046 13.1 0.3 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain Gtr1_RagA PF04670.7 GAO83551.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 GAO83551.1 - 0.085 13.1 0.1 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAO83551.1 - 0.094 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAO83551.1 - 0.13 12.5 0.2 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAO83551.1 - 0.14 12.0 2.6 0.35 10.8 0.4 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit p450 PF00067.17 GAO83552.1 - 5.8e-73 245.9 0.0 7.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nucleoside_tran PF01733.13 GAO83552.1 - 9.7e-15 54.5 8.5 2e-13 50.2 1.9 2.3 1 1 1 2 2 2 2 Nucleoside transporter RhodobacterPufX PF11511.3 GAO83552.1 - 5.2 6.5 7.5 1.4 8.3 0.0 3.6 4 1 1 5 5 5 0 Intrinsic membrane protein PufX DUF3635 PF12330.3 GAO83553.1 - 4.6e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) APH PF01636.18 GAO83553.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2404 PF10296.4 GAO83554.1 - 0.00052 20.0 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 GAO83555.1 - 1.2e-115 385.7 0.3 1.4e-115 385.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2140 PF09911.4 GAO83555.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Polysacc_deac_1 PF01522.16 GAO83556.1 - 7.1e-27 93.4 0.0 1.5e-26 92.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 GAO83556.1 - 0.00066 18.6 0.0 0.00098 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Nitroreductase PF00881.19 GAO83557.1 - 1.1e-15 57.8 0.0 1.3e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Ins_P5_2-kin PF06090.7 GAO83558.1 - 6.4e-80 268.5 0.0 7.4e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 GAO83559.1 - 9.8e-33 111.7 0.0 1.1e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 PPR PF01535.15 GAO83561.1 - 0.014 15.3 0.0 22 5.3 0.0 4.0 3 0 0 3 3 3 0 PPR repeat COX7a PF02238.10 GAO83562.1 - 0.23 11.2 1.4 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Fungal_trans PF04082.13 GAO83563.1 - 7.6e-14 51.1 0.5 1.6e-13 50.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83563.1 - 4.8e-07 29.5 12.0 8.4e-07 28.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1345 PF07077.6 GAO83564.1 - 0.0039 16.7 3.4 0.15 11.6 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1345) Bac_rhodopsin PF01036.13 GAO83564.1 - 0.026 13.8 5.4 0.052 12.8 2.9 1.9 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein PgaD PF13994.1 GAO83564.1 - 0.071 12.5 6.1 0.13 11.7 0.3 2.3 2 0 0 2 2 2 0 PgaD-like protein DUF998 PF06197.8 GAO83564.1 - 0.14 11.4 8.9 0.5 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF2637 PF10935.3 GAO83564.1 - 0.17 11.8 6.9 2.2 8.2 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2637) DUF1129 PF06570.6 GAO83564.1 - 0.2 10.9 3.5 4.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MARVEL PF01284.18 GAO83564.1 - 0.36 10.6 7.7 1.2 8.9 2.1 2.3 2 0 0 2 2 2 0 Membrane-associating domain MNHE PF01899.11 GAO83564.1 - 1.2 8.7 7.0 0.38 10.3 0.4 2.2 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit p53-inducible11 PF14936.1 GAO83564.1 - 1.6 8.6 5.8 1 9.2 0.7 2.2 1 1 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF805 PF05656.9 GAO83564.1 - 3.5 7.4 11.0 7.7 6.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF4131 PF13567.1 GAO83564.1 - 9.4 5.6 9.2 16 4.8 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Aminotran_5 PF00266.14 GAO83565.1 - 1.1e-11 44.1 0.0 1.1e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V NUMOD4 PF07463.6 GAO83565.1 - 0.053 13.4 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 NUMOD4 motif IDO PF01231.13 GAO83566.1 - 5e-168 558.9 0.0 5.7e-168 558.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 GAO83566.1 - 0.00031 19.3 0.1 0.008 14.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) YEATS PF03366.11 GAO83567.1 - 1.4e-35 120.8 1.1 2.2e-35 120.2 0.8 1.3 1 0 0 1 1 1 1 YEATS family DUF334 PF03904.8 GAO83567.1 - 0.72 9.1 4.4 1.5 8.1 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF334) NAD_binding_10 PF13460.1 GAO83568.1 - 1e-11 45.1 0.0 1.4e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO83568.1 - 3.2e-08 33.2 0.0 9.8e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO83568.1 - 3.3e-05 22.7 0.0 0.00011 21.0 0.0 1.8 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO83568.1 - 0.00074 19.4 0.0 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAO83568.1 - 0.0038 16.1 0.0 0.022 13.6 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAO83568.1 - 0.0077 15.1 0.1 1.4 7.8 0.1 2.6 2 2 0 2 2 2 2 Male sterility protein SYF2 PF08231.7 GAO83569.1 - 2.5e-54 183.5 13.8 2.5e-54 183.5 9.5 2.1 2 0 0 2 2 2 2 SYF2 splicing factor EF-1_beta_acid PF10587.4 GAO83569.1 - 0.061 13.4 2.3 0.48 10.6 1.6 2.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Velvet PF11754.3 GAO83571.1 - 8.2e-69 231.2 0.0 1.2e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Sel1 PF08238.7 GAO83572.1 - 0.89 10.2 4.3 6.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat Ribosomal_L12 PF00542.14 GAO83573.1 - 8.2e-18 64.1 8.5 9.5e-17 60.7 4.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DEC-1_N PF04625.8 GAO83573.1 - 2.5 6.6 7.4 3.9 6.0 3.3 1.9 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region DUF3306 PF11748.3 GAO83573.1 - 5.2 7.7 5.6 66 4.2 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Cpn60_TCP1 PF00118.19 GAO83574.1 - 8e-134 446.8 1.9 3.3e-132 441.5 1.3 2.1 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.13 GAO83574.1 - 1.7e-33 116.1 0.0 4.9e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 Fungal_trans_2 PF11951.3 GAO83575.1 - 1.5e-85 287.1 0.1 2.6e-85 286.3 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83575.1 - 3.1e-05 23.7 12.3 5.4e-05 23.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H PF00075.19 GAO83578.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 RNase H SHR3_chaperone PF08229.6 GAO83579.1 - 2.7e-75 251.6 0.0 3.4e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tad PF13400.1 GAO83579.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.7 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like Arrestin_N PF00339.24 GAO83580.1 - 8.7e-15 54.8 0.0 7e-13 48.6 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAO83580.1 - 2.6e-07 30.7 0.0 3.9e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain U-box PF04564.10 GAO83580.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 U-box domain Mnd1 PF03962.10 GAO83581.1 - 4.2e-55 186.3 7.9 5e-55 186.1 5.5 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 GAO83581.1 - 0.00088 18.8 7.8 0.0035 16.9 5.5 1.8 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 GAO83581.1 - 0.0026 17.3 9.4 0.0033 17.0 6.5 1.3 1 0 0 1 1 1 1 IncA protein DUF342 PF03961.8 GAO83581.1 - 0.0078 14.6 4.3 0.01 14.3 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF2201_N PF13203.1 GAO83581.1 - 0.097 11.8 6.3 0.12 11.5 4.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3584 PF12128.3 GAO83581.1 - 0.17 9.1 11.8 0.29 8.3 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 GAO83581.1 - 0.18 10.7 13.0 0.48 9.3 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rb_C PF08934.5 GAO83581.1 - 0.21 11.2 2.0 0.36 10.4 1.4 1.4 1 0 0 1 1 1 0 Rb C-terminal domain V_ATPase_I PF01496.14 GAO83581.1 - 0.28 8.9 2.0 0.34 8.6 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 GAO83581.1 - 0.39 9.0 5.9 0.54 8.6 4.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.4 GAO83581.1 - 0.48 9.3 10.5 0.87 8.4 7.3 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 GAO83581.1 - 4.4 7.0 20.4 13 5.5 10.4 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 GAO83581.1 - 4.9 7.0 14.1 4.8 7.0 0.7 3.3 3 0 0 3 3 3 0 Basic region leucine zipper UAF_Rrn10 PF05234.6 GAO83582.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 WD40 PF00400.27 GAO83583.1 - 2.1e-29 100.2 14.3 3.3e-08 33.0 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAO83583.1 - 0.00067 18.5 0.0 1.2 7.8 0.0 3.6 2 1 0 3 3 3 2 Nup133 N terminal like GTP1_OBG PF01018.17 GAO83585.1 - 0.0011 18.6 25.8 1.3 8.6 0.1 7.2 7 0 0 7 7 7 6 GTP1/OBG PAZ PF02170.17 GAO83585.1 - 0.0035 16.6 10.3 4.6 6.5 0.1 4.9 5 1 0 5 5 5 4 PAZ domain HRXXH PF13933.1 GAO83587.1 - 2.2e-106 354.8 0.0 2.5e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Acetyltransf_10 PF13673.1 GAO83588.1 - 5.5e-10 39.3 0.0 9e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO83588.1 - 4.1e-09 36.4 0.0 1.4e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO83588.1 - 1e-08 35.0 0.1 3.2e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAO83588.1 - 2.4e-08 33.8 0.0 2.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO83588.1 - 0.05 13.4 0.1 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 GAO83589.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO83589.1 - 2.7e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO83589.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAO83589.1 - 0.00041 20.4 0.0 0.00067 19.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO83589.1 - 0.0036 17.1 0.0 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO83589.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Hydrophobin PF01185.13 GAO83590.1 - 2.6e-14 53.4 7.3 3.3e-14 53.0 5.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Synaptobrevin PF00957.16 GAO83591.1 - 1.9e-14 52.9 0.3 4.1e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAO83591.1 - 3e-10 39.4 0.0 5.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain LemA PF04011.7 GAO83591.1 - 0.015 14.4 0.0 0.091 11.8 0.0 1.9 2 0 0 2 2 2 0 LemA family PfkB PF00294.19 GAO83594.1 - 2.8e-13 49.6 0.0 3.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_10 PF00331.15 GAO83595.1 - 3.7e-102 341.6 1.9 6.7e-100 334.2 1.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 p450 PF00067.17 GAO83595.1 - 2e-54 184.8 0.0 2.7e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cellulase-like PF12876.2 GAO83595.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Sugar-binding cellulase-like Myc_target_1 PF15179.1 GAO83595.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Myc target protein 1 NACHT PF05729.7 GAO83596.1 - 6.7e-08 32.3 0.0 2.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAO83596.1 - 5.4e-07 29.7 0.0 9.4e-06 25.7 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAO83596.1 - 0.002 18.2 0.0 0.024 14.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 GAO83596.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAO83596.1 - 0.0055 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO83596.1 - 0.064 12.9 0.1 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 GAO83596.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Torsin Herpes_capsid PF06112.6 GAO83597.1 - 0.11 12.5 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Herpes_US9 PF06072.6 GAO83597.1 - 1.6 8.6 4.1 2.5 7.9 2.9 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 E1-E2_ATPase PF00122.15 GAO83598.1 - 6.2e-64 215.1 1.0 1.2e-63 214.2 0.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO83598.1 - 1.9e-34 118.8 7.7 1.9e-34 118.8 5.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO83598.1 - 7.2e-30 105.0 0.0 1e-28 101.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO83598.1 - 5.8e-19 67.3 0.0 1.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAO83598.1 - 2.6e-16 59.3 0.0 6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO83598.1 - 1.3e-12 48.3 0.0 4.1e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO83598.1 - 2.2e-06 27.4 0.9 0.00057 19.5 0.9 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pro_CA PF00484.14 GAO83599.1 - 6.7e-19 68.3 0.0 4.2e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Carbonic anhydrase SLAC1 PF03595.12 GAO83600.1 - 2.3e-48 164.5 27.9 5.5e-45 153.4 14.1 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel YrhC PF14143.1 GAO83600.1 - 0.085 12.8 0.2 0.27 11.1 0.1 1.9 1 0 0 1 1 1 0 YrhC-like protein Kelch_5 PF13854.1 GAO83601.1 - 0.0001 22.1 0.1 0.0001 22.1 0.1 3.2 3 0 0 3 3 3 1 Kelch motif Spc97_Spc98 PF04130.8 GAO83601.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Spc97 / Spc98 family Podoplanin PF05808.6 GAO83602.1 - 0.013 15.0 0.3 0.021 14.3 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.6 GAO83602.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Protocadherin Lamp PF01299.12 GAO83602.1 - 4.5 6.3 8.7 0.97 8.5 3.2 1.9 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Shisa PF13908.1 GAO83602.1 - 5.8 7.0 23.9 0.24 11.5 6.5 3.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SH3_9 PF14604.1 GAO83603.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO83603.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain 3-PAP PF12578.3 GAO83603.1 - 0.037 13.8 0.6 0.037 13.8 0.4 3.5 3 0 0 3 3 3 0 Myotubularin-associated protein DUF2207 PF09972.4 GAO83603.1 - 0.067 11.7 0.1 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP-synt_C PF00137.16 GAO83604.1 - 3.2e-14 52.5 11.0 4.6e-14 52.0 7.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Oxidored-like PF09791.4 GAO83605.1 - 2.1e-05 23.8 8.2 3.3e-05 23.2 5.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF4139 PF13598.1 GAO83606.1 - 1.1e-56 192.4 10.0 8.1e-43 146.9 0.0 3.2 2 2 2 4 4 4 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 GAO83606.1 - 3.8e-14 52.9 2.1 3.8e-14 52.9 1.4 4.6 2 2 1 3 3 3 2 N-terminal domain of unknown function (DUF4140) DPPIV_N PF00930.16 GAO83607.1 - 2.7e-113 378.1 0.2 3.6e-113 377.7 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAO83607.1 - 2.2e-41 141.4 1.6 3.8e-41 140.6 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO83607.1 - 6.5e-06 25.9 0.2 1.5e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO83607.1 - 0.00069 19.5 0.6 0.0045 16.8 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 GAO83609.1 - 9.1e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAO83609.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO83609.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO83609.1 - 0.1 12.7 0.0 0.88 9.7 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PALP PF00291.20 GAO83610.1 - 4.7e-43 147.5 2.7 6.2e-43 147.1 1.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DnaJ PF00226.26 GAO83611.1 - 1.1e-20 73.1 2.4 2.9e-20 71.7 1.7 1.8 1 0 0 1 1 1 1 DnaJ domain Seryl_tRNA_N PF02403.17 GAO83611.1 - 1.1 9.2 14.6 7.5 6.6 1.5 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.1 GAO83611.1 - 2.6 7.1 10.7 0.16 11.1 1.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Ank_2 PF12796.2 GAO83612.1 - 1.6e-90 297.5 1.3 4.8e-23 81.3 0.0 4.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83612.1 - 4e-64 209.3 1.4 5.1e-08 32.3 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 GAO83612.1 - 2e-47 154.4 0.0 3.4e-05 23.6 0.0 8.8 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 GAO83612.1 - 2.2e-41 138.9 2.7 1.2e-08 34.9 0.0 6.6 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO83612.1 - 1e-37 127.8 0.5 1.4e-08 35.0 0.0 6.4 3 2 5 8 8 8 6 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAO83612.1 - 0.00029 19.9 0.0 0.042 12.8 0.0 2.6 2 0 0 2 2 2 2 Phosphorylase superfamily Methyltransf_29 PF03141.11 GAO83612.1 - 0.0051 15.2 1.0 6.1 5.0 0.0 3.4 1 1 3 4 4 4 2 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4350 PF14258.1 GAO83612.1 - 0.011 15.8 1.1 91 3.3 0.0 6.0 5 2 2 7 7 7 0 Domain of unknown function (DUF4350) AAA PF00004.24 GAO83612.1 - 0.026 14.7 0.0 0.15 12.2 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AMP-binding PF00501.23 GAO83613.1 - 8.1e-72 241.8 0.0 1.2e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO83613.1 - 1.1e-57 194.8 0.0 6e-57 192.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 GAO83613.1 - 2.8e-15 56.3 0.0 9.4e-15 54.6 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 GAO83613.1 - 1.3e-11 45.2 0.1 4.9e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAO83613.1 - 7.6e-09 34.6 0.0 1.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAO83613.1 - 7.3e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 GAO83613.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAO83613.1 - 0.0078 16.5 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 GAO83613.1 - 0.016 15.1 0.1 0.075 12.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Aminotran_1_2 PF00155.16 GAO83614.1 - 5.9e-36 124.1 0.0 7.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAO83614.1 - 0.004 15.4 0.0 0.0071 14.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 GAO83614.1 - 0.028 12.9 0.0 0.16 10.4 0.0 1.9 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 GAO83614.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF357 PF04010.8 GAO83614.1 - 0.044 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) AMP-binding PF00501.23 GAO83615.1 - 5.8e-76 255.5 0.0 1.1e-75 254.6 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO83615.1 - 4.5e-58 196.0 0.0 6.7e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAO83615.1 - 2.4e-13 50.0 0.0 1.3e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO83615.1 - 8.2e-12 45.2 0.0 2.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO83615.1 - 2.4e-08 34.7 0.0 1.7e-07 32.1 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAO83615.1 - 6.5e-07 28.3 0.0 1.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAO83615.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAO83615.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAO83616.1 - 2.1e-32 112.0 0.0 3.4e-16 58.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 GAO83616.1 - 3.5e-07 29.9 0.0 0.0015 18.0 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO83616.1 - 0.00018 20.2 0.0 0.15 10.7 0.0 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO83616.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAO83616.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain INTS2 PF14750.1 GAO83616.1 - 0.089 10.3 0.0 0.11 9.9 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 MFS_1 PF07690.11 GAO83617.1 - 8.8e-29 100.3 39.5 2.2e-27 95.7 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 GAO83617.1 - 6.3e-06 24.9 9.8 6.3e-06 24.9 6.8 2.5 2 2 0 2 2 2 1 Vacuole effluxer Atg22 like DUF2678 PF10856.3 GAO83617.1 - 0.15 11.7 2.7 12 5.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2678) Fungal_trans PF04082.13 GAO83618.1 - 7.4e-12 44.6 1.8 1.1e-11 44.0 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 GAO83618.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Glyco_hydro_18 PF00704.23 GAO83619.1 - 9.7e-53 179.8 5.8 1.4e-52 179.2 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAO83619.1 - 7.5e-16 57.7 0.5 0.0011 18.8 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 GAO83619.1 - 0.00012 22.0 3.3 0.00012 22.0 2.3 3.9 4 0 0 4 4 4 1 Chitin recognition protein Glyco_hydro_2_N PF02837.13 GAO83622.1 - 0.03 13.8 0.0 2.8 7.4 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, sugar binding domain zf-B_box PF00643.19 GAO83624.1 - 3.1 7.7 5.1 11 6.0 0.8 2.5 1 1 1 2 2 2 0 B-box zinc finger Ank_2 PF12796.2 GAO83626.1 - 7.2e-26 90.3 0.0 2e-10 40.8 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83626.1 - 3.1e-20 70.8 2.1 1.3e-06 27.9 0.0 6.8 6 2 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 GAO83626.1 - 3.4e-18 65.6 0.0 1.5e-05 25.3 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83626.1 - 4.4e-12 44.9 0.2 0.00027 20.8 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAO83626.1 - 4.7e-12 45.7 0.4 9.9e-05 22.4 0.0 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) adh_short PF00106.20 GAO83627.1 - 4.8e-24 85.1 0.5 7.9e-24 84.4 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83627.1 - 8.1e-17 61.7 0.0 5.8e-16 58.9 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO83627.1 - 2.3e-09 37.5 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO83627.1 - 1.2e-06 28.2 0.4 1.9e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO83627.1 - 2.5e-06 27.0 0.0 3.9e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAO83627.1 - 5.1e-06 25.8 0.0 6e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Saccharop_dh PF03435.13 GAO83627.1 - 1.9e-05 23.8 0.1 2.7e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 GAO83627.1 - 0.00083 18.6 0.1 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAO83627.1 - 0.0044 15.7 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO83627.1 - 0.0053 15.6 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 GAO83627.1 - 0.006 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 GAO83627.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Cellulase PF00150.13 GAO83629.1 - 5.2e-17 61.9 8.4 1.1e-16 60.8 5.8 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 GAO83631.1 - 5.7e-24 84.9 4.5 1.1e-23 83.9 2.4 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO83631.1 - 7.3e-15 55.0 2.1 7.3e-15 55.0 1.4 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAO83631.1 - 8.3e-09 34.7 0.3 1.1e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAO83631.1 - 7.3e-08 32.1 0.3 2.3e-07 30.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO83631.1 - 0.0016 18.1 0.3 0.0039 16.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1772 PF08592.6 GAO83632.1 - 2.1e-31 108.5 5.8 2.4e-31 108.3 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2391 PF09622.5 GAO83632.1 - 0.043 12.9 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) ketoacyl-synt PF00109.21 GAO83635.1 - 2e-66 224.0 0.1 4.5e-66 222.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO83635.1 - 5.8e-61 206.5 0.0 2.2e-60 204.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 GAO83635.1 - 1.8e-59 200.4 0.3 4.4e-59 199.1 0.1 1.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAO83635.1 - 1e-52 179.2 0.0 1.8e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAO83635.1 - 9.9e-45 152.4 0.1 2.7e-44 151.0 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO83635.1 - 6.4e-29 100.2 0.3 1.4e-28 99.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAO83635.1 - 5.3e-15 55.1 0.0 1.7e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAO83635.1 - 1.5e-08 34.7 1.1 4.6e-08 33.2 0.8 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAO83635.1 - 4.9e-08 32.7 0.4 1.4e-07 31.2 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO83635.1 - 4.6e-06 27.5 0.0 1.8e-05 25.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 GAO83635.1 - 0.00019 20.4 0.0 0.00052 19.0 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 GAO83635.1 - 0.011 16.1 0.0 0.055 13.9 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83635.1 - 0.25 10.9 0.0 0.56 9.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 GAO83638.1 - 8.1e-24 84.8 0.0 1.9e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO83638.1 - 2.7e-18 65.5 0.1 6e-15 54.4 0.0 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO83638.1 - 3.1e-12 46.0 0.2 1.6e-08 33.8 0.1 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO83638.1 - 1.5e-11 44.5 0.0 0.00035 20.5 0.0 3.1 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO83638.1 - 1.8e-08 34.6 0.4 0.0022 18.3 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO83638.1 - 1.9e-08 34.2 0.0 3e-06 27.1 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAO83638.1 - 5.2e-06 26.2 0.0 0.00089 18.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO83638.1 - 3.7e-05 22.9 0.1 0.042 12.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 GAO83638.1 - 4.5e-05 22.5 0.4 0.089 11.6 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO83638.1 - 0.00012 21.9 0.2 0.61 9.8 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAO83638.1 - 0.00048 19.2 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 GAO83638.1 - 0.00054 20.0 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 GAO83638.1 - 0.0019 18.1 0.3 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 GAO83638.1 - 0.002 17.2 0.1 1.1 8.3 0.0 3.3 3 1 0 4 4 4 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 GAO83638.1 - 0.0021 17.8 0.0 0.1 12.3 0.0 2.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 GAO83638.1 - 0.0021 16.5 0.0 0.049 12.0 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.1 GAO83638.1 - 0.0034 17.6 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.11 GAO83638.1 - 0.0037 16.6 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAO83638.1 - 0.0039 16.1 0.3 1.3 7.7 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A SnoaL_2 PF12680.2 GAO83638.1 - 0.0056 17.0 1.7 0.029 14.7 0.0 2.9 3 1 0 3 3 2 1 SnoaL-like domain IlvN PF07991.7 GAO83638.1 - 0.0059 15.9 0.2 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 GAO83638.1 - 0.011 14.6 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 GAO83638.1 - 0.013 14.4 0.0 0.23 10.3 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein SBP_bac_5 PF00496.17 GAO83638.1 - 0.022 13.6 0.0 0.77 8.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle F420_oxidored PF03807.12 GAO83638.1 - 0.054 13.9 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 GAO83638.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 GAO83638.1 - 0.1 12.1 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAO83638.1 - 0.17 11.2 0.2 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 GAO83640.1 - 1.6e-38 132.4 23.1 1.8e-28 99.3 3.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO83640.1 - 4.1e-28 98.1 18.3 4.1e-28 98.1 12.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 GAO83640.1 - 1.8e-07 30.0 16.9 7.2e-05 21.4 3.0 3.0 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 GAO83640.1 - 0.0026 16.2 8.4 0.0026 16.2 5.8 3.2 3 1 1 4 4 4 3 MFS/sugar transport protein DUF3666 PF12408.3 GAO83641.1 - 0.071 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Methyltransf_11 PF08241.7 GAO83642.1 - 7.7e-23 80.8 0.0 2.2e-22 79.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO83642.1 - 4.9e-17 61.9 0.0 7.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO83642.1 - 1.6e-15 57.2 0.1 6.2e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO83642.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO83642.1 - 2e-13 50.6 0.0 5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO83642.1 - 1.9e-11 43.5 0.0 2.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAO83642.1 - 4e-11 43.4 0.1 1.3e-10 41.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 GAO83642.1 - 2.1e-09 36.8 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 GAO83642.1 - 3e-09 36.9 0.0 3.5e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAO83642.1 - 6.1e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 GAO83642.1 - 0.00014 21.3 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 GAO83642.1 - 0.00026 20.0 0.0 0.0008 18.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 GAO83642.1 - 0.00075 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 GAO83642.1 - 0.00075 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 GAO83642.1 - 0.0011 18.0 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 GAO83642.1 - 0.0016 18.1 0.0 0.023 14.3 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.15 GAO83642.1 - 0.0032 16.5 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 GAO83642.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO83642.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SET PF00856.23 GAO83643.1 - 4e-08 33.7 0.1 1.5e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 SET domain TMP_2 PF06791.8 GAO83643.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Prophage tail length tape measure protein HCO3_cotransp PF00955.16 GAO83644.1 - 7.7e-42 143.6 13.6 8.2e-26 90.7 2.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Ank_2 PF12796.2 GAO83645.1 - 5.1e-193 626.0 53.1 2.2e-20 72.7 0.0 10.0 1 1 14 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83645.1 - 5.5e-109 350.9 56.4 5.5e-08 32.2 0.1 21.9 23 0 0 23 23 23 19 Ankyrin repeat Ank_3 PF13606.1 GAO83645.1 - 9.9e-89 282.3 29.8 0.00015 21.6 0.0 21.5 22 0 0 22 22 22 20 Ankyrin repeat Ank_4 PF13637.1 GAO83645.1 - 6.1e-83 271.8 14.2 4.2e-11 43.0 0.0 15.6 9 4 8 17 17 17 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO83645.1 - 1e-61 203.5 43.1 7.1e-07 29.2 0.1 19.1 11 5 9 20 20 20 16 Ankyrin repeats (many copies) Clr5 PF14420.1 GAO83645.1 - 3.4e-17 62.0 7.1 5.9e-17 61.3 4.9 1.4 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 GAO83645.1 - 9.6e-08 31.8 1.1 0.71 9.3 0.0 6.8 7 2 2 9 9 9 2 Shigella flexneri OspC protein HTH_33 PF13592.1 GAO83645.1 - 0.054 13.0 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix ABC_tran PF00005.22 GAO83647.1 - 3.7e-48 163.2 0.4 3.6e-28 98.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 GAO83647.1 - 2.1e-47 161.8 36.1 3.4e-24 85.7 13.7 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 GAO83647.1 - 1.3e-07 31.8 0.2 0.26 11.2 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 GAO83647.1 - 1.2e-06 27.8 4.6 0.24 10.5 0.1 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAO83647.1 - 5.5e-06 25.8 1.8 0.039 13.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAO83647.1 - 2e-05 24.4 0.0 0.046 13.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAO83647.1 - 9.9e-05 23.1 0.0 0.46 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAO83647.1 - 0.00015 22.2 0.8 0.49 10.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 GAO83647.1 - 0.0006 19.8 5.6 0.23 11.4 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 GAO83647.1 - 0.00061 19.0 0.7 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAO83647.1 - 0.0011 18.4 0.0 0.83 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain ArgK PF03308.11 GAO83647.1 - 0.0038 16.0 0.5 1.1 7.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein Zeta_toxin PF06414.7 GAO83647.1 - 0.0059 15.7 0.1 3.1 6.8 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 GAO83647.1 - 0.0095 16.2 6.2 0.33 11.2 0.2 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 GAO83647.1 - 0.01 15.9 2.1 7.6 6.6 0.4 3.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO83647.1 - 0.022 15.0 0.4 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAO83647.1 - 0.023 14.5 4.5 0.17 11.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 GAO83647.1 - 0.023 14.1 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 GAO83647.1 - 0.034 13.6 0.5 7.2 6.0 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 GAO83647.1 - 0.13 12.0 8.8 0.1 12.3 0.1 3.0 3 0 0 3 3 3 0 Dynamin family MobB PF03205.9 GAO83647.1 - 0.19 11.4 0.7 21 4.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 GAO83647.1 - 0.26 10.8 3.7 4.8 6.7 0.1 3.1 3 0 0 3 3 3 0 AAA domain Aminotran_3 PF00202.16 GAO83648.1 - 3.1e-107 358.3 0.0 3.8e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAO83648.1 - 0.0018 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO83648.1 - 0.0058 15.8 0.0 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Glyco_transf_22 PF03901.12 GAO83649.1 - 2e-80 270.8 15.2 2.4e-80 270.5 10.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ArfGap PF01412.13 GAO83650.1 - 2.1e-38 130.7 0.1 3.8e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 GAO83650.1 - 0.04 13.7 0.1 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Rsm1 PF08600.5 GAO83650.1 - 0.11 12.4 0.4 3.3 7.6 0.0 2.9 3 0 0 3 3 3 0 Rsm1-like peroxidase PF00141.18 GAO83651.1 - 3.2e-51 174.0 0.0 4.9e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-CSL PF05207.8 GAO83652.1 - 1.5e-15 56.3 2.2 2.3e-15 55.8 1.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 GAO83652.1 - 4.7e-14 51.8 0.8 1.2e-13 50.6 0.6 1.6 1 1 0 1 1 1 1 DnaJ domain PAG PF15347.1 GAO83652.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched PITH PF06201.8 GAO83653.1 - 8.9e-42 142.4 0.0 1.2e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 GAO83653.1 - 1.6e-28 98.3 0.0 2.8e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAO83653.1 - 8.3e-08 32.2 0.0 9.8e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAO83653.1 - 9.4e-07 29.0 0.1 4.1e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 GAO83653.1 - 6.5e-05 22.6 0.3 0.04 13.5 0.0 2.4 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 GAO83653.1 - 0.0019 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAO83653.1 - 0.0019 17.7 0.3 0.5 9.9 0.0 2.3 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 GAO83653.1 - 0.004 16.7 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 GAO83653.1 - 0.031 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-C2H2 PF00096.21 GAO83654.1 - 4.7e-10 39.1 20.9 1.9e-06 27.8 1.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO83654.1 - 7.7e-09 35.2 15.8 0.00023 21.2 3.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO83654.1 - 2e-05 24.6 6.4 2e-05 24.6 4.4 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAO83654.1 - 0.00038 20.5 10.5 0.0069 16.4 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO83654.1 - 0.0027 17.8 0.5 0.0027 17.8 0.4 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAO83654.1 - 0.03 14.2 11.1 0.032 14.1 0.7 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAO83654.1 - 3.5 7.8 7.0 15 5.7 0.3 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ATP_bind_4 PF01902.12 GAO83655.1 - 2.9e-17 62.7 0.0 6.6e-05 22.3 0.0 3.9 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 GAO83655.1 - 9.2e-17 60.9 0.0 7.5e-09 35.4 0.0 3.2 3 0 0 3 3 3 2 Endoribonuclease L-PSP Ribosomal_60s PF00428.14 GAO83655.1 - 0.019 15.3 0.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CTP_transf_1 PF01148.15 GAO83656.1 - 1.5e-10 41.2 9.5 1.5e-05 24.8 1.8 3.0 2 0 0 2 2 2 2 Cytidylyltransferase family Prp19_bind PF06991.6 GAO83656.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF3543 PF12063.3 GAO83657.1 - 2e-100 334.9 0.0 2.9e-100 334.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) AA_permease_2 PF13520.1 GAO83657.1 - 9.2e-91 304.4 39.4 1.4e-90 303.8 27.3 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 GAO83657.1 - 1.7e-62 210.9 0.0 2.7e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83657.1 - 2e-42 145.0 0.0 3.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AA_permease PF00324.16 GAO83657.1 - 1.2e-18 66.6 36.2 2e-18 66.0 25.1 1.2 1 0 0 1 1 1 1 Amino acid permease Kinase-like PF14531.1 GAO83657.1 - 0.0081 15.1 0.0 0.26 10.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DPM3 PF08285.6 GAO83657.1 - 2.7 7.9 4.6 11 5.9 3.2 2.1 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Peptidase_M1 PF01433.15 GAO83658.1 - 4.6e-145 483.5 0.3 5.8e-145 483.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 GAO83658.1 - 2.5e-97 326.0 0.5 7.6e-97 324.4 0.1 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAO83658.1 - 3.9e-19 68.9 0.1 7e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 GAO83658.1 - 8.8e-05 22.1 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF2059 PF09832.4 GAO83658.1 - 0.032 14.2 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) DEAD PF00270.24 GAO83659.1 - 1.5e-41 141.6 0.0 1.4e-40 138.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO83659.1 - 8.1e-26 89.7 0.1 2e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 GAO83659.1 - 0.0065 16.7 4.1 0.023 15.0 2.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) CCDC50_N PF15295.1 GAO83659.1 - 0.095 12.6 2.6 0.28 11.0 1.8 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF3334 PF11813.3 GAO83659.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Suf PF05843.9 GAO83660.1 - 2.3e-05 24.2 3.0 0.0083 15.8 0.1 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 GAO83660.1 - 0.0016 19.0 0.0 0.0016 19.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83660.1 - 0.0024 18.3 11.8 10 7.0 0.0 7.2 6 2 0 6 6 6 2 Tetratricopeptide repeat FAT PF02259.18 GAO83660.1 - 0.0077 15.2 1.8 0.033 13.1 0.1 2.7 2 2 2 4 4 4 1 FAT domain NRDE-2 PF08424.5 GAO83660.1 - 0.039 12.8 8.6 0.13 11.1 0.7 3.8 4 1 0 4 4 4 0 NRDE-2, necessary for RNA interference MOSC_N PF03476.11 GAO83662.1 - 2.8e-30 104.4 0.0 8.8e-30 102.8 0.0 1.9 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 GAO83662.1 - 2e-24 86.0 0.0 3.2e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 GAO83662.1 - 2.1e-22 79.0 0.0 4e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain DUF2244 PF10003.4 GAO83663.1 - 0.038 13.3 5.4 0.77 9.1 0.0 2.5 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) HemY_N PF07219.8 GAO83663.1 - 0.099 12.2 5.2 4.6 6.8 0.9 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF4282 PF14110.1 GAO83663.1 - 1.3 9.2 12.3 0.37 10.9 3.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) 7TMR-DISM_7TM PF07695.6 GAO83663.1 - 5.9 6.4 18.5 0.31 10.6 6.9 2.1 1 1 0 2 2 2 0 7TM diverse intracellular signalling PAP2 PF01569.16 GAO83664.1 - 7.2e-28 96.8 0.2 1.8e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 PAP2 superfamily StbA PF06406.6 GAO83664.1 - 0.2 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 StbA protein But2 PF09792.4 GAO83665.1 - 9e-59 197.3 3.4 9e-59 197.3 2.4 2.4 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain CC PF04942.9 GAO83665.1 - 4.1 7.3 9.0 9.2 6.2 0.1 3.4 3 0 0 3 3 3 0 CC domain NGP1NT PF08153.7 GAO83667.1 - 8.8e-48 161.5 0.0 1.4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 GAO83667.1 - 1.6e-19 69.9 0.1 1.2e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO83667.1 - 3.5e-06 26.3 0.0 6.5e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAO83667.1 - 0.00018 21.3 0.2 0.31 10.8 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 GAO83667.1 - 0.00049 19.3 0.1 0.12 11.5 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO83667.1 - 0.0011 18.4 0.0 0.26 10.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAO83667.1 - 0.0037 16.4 0.0 0.0074 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO83667.1 - 0.0071 16.8 0.1 2.7 8.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Pkinase PF00069.20 GAO83668.1 - 2.6e-40 138.2 0.0 9.8e-40 136.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83668.1 - 3.3e-27 95.2 0.0 4.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO83668.1 - 0.012 15.3 2.7 0.22 11.2 0.2 3.1 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 GAO83668.1 - 0.014 14.5 0.1 0.046 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAO83668.1 - 0.16 10.7 0.0 0.59 8.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 GAO83669.1 - 4.2e-40 135.5 0.8 1.6e-39 133.6 0.5 2.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 GAO83669.1 - 3.5e-25 88.7 0.4 3.5e-25 88.7 0.3 6.0 5 2 1 6 6 6 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 GAO83669.1 - 0.0013 18.3 1.3 0.0058 16.2 0.9 2.1 1 1 0 1 1 1 1 Prefoldin subunit DMPK_coil PF08826.5 GAO83669.1 - 0.015 15.1 2.4 6 6.8 0.0 3.1 2 0 0 2 2 2 0 DMPK coiled coil domain like RNA_pol_Rpc82 PF05645.8 GAO83669.1 - 0.33 10.4 6.2 0.077 12.5 0.9 2.2 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 MAT1 PF06391.8 GAO83670.1 - 6.8e-36 123.7 16.2 9e-36 123.3 11.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 GAO83670.1 - 0.00019 21.0 4.2 0.00058 19.4 2.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO83670.1 - 0.0015 18.5 6.0 0.0034 17.3 4.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO83670.1 - 0.0015 18.1 5.9 0.0029 17.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO83670.1 - 0.0038 17.0 5.3 0.0082 15.9 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 GAO83670.1 - 0.018 14.5 5.7 0.21 11.2 1.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 GAO83670.1 - 0.026 14.2 9.1 0.25 11.0 6.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Aldo_ket_red PF00248.16 GAO83671.1 - 1.7e-52 177.9 0.0 2.2e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldose_epim PF01263.15 GAO83672.1 - 4.2e-42 144.2 0.0 4.8e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1717 PF05414.6 GAO83672.1 - 0.043 14.2 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) CARDB PF07705.6 GAO83672.1 - 0.1 12.6 0.3 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 CARDB AA_permease_2 PF13520.1 GAO83673.1 - 1.9e-31 109.0 36.1 1.7e-29 102.5 25.0 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO83673.1 - 4.4e-16 58.2 32.5 8.7e-14 50.7 22.5 2.9 1 1 0 1 1 1 1 Amino acid permease Rif1_N PF12231.3 GAO83676.1 - 1.8e-148 494.4 1.3 2.6e-148 493.9 0.9 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 GAO83677.1 - 4.1e-137 457.6 0.0 4.9e-137 457.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn ABC_membrane PF00664.18 GAO83678.1 - 1.3e-68 231.3 27.1 3.1e-35 121.9 4.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO83678.1 - 7.5e-37 126.6 0.0 2.1e-24 86.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Polysacc_synt_4 PF04669.8 GAO83678.1 - 4.1e-23 81.7 0.3 1e-22 80.4 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis SMC_N PF02463.14 GAO83678.1 - 5.1e-17 61.8 0.5 4.3e-07 29.3 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO83678.1 - 1.4e-08 35.0 0.0 0.0055 16.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAO83678.1 - 0.0012 18.6 0.0 0.21 11.4 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 GAO83678.1 - 0.0013 18.7 0.0 0.0045 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO83678.1 - 0.0028 17.8 0.3 0.067 13.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAO83678.1 - 0.0034 16.8 0.1 0.0086 15.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAO83678.1 - 0.0046 15.5 0.2 0.49 8.9 0.2 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 GAO83678.1 - 0.0055 16.4 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 GAO83678.1 - 0.0055 16.2 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 GAO83678.1 - 0.022 14.1 0.1 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAO83678.1 - 0.042 14.6 0.1 0.14 12.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 GAO83678.1 - 0.13 12.0 0.2 0.32 10.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 GAO83678.1 - 0.17 12.1 0.8 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 GAO83678.1 - 0.42 9.0 0.1 12 4.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DLH PF01738.13 GAO83679.1 - 7.8e-22 77.6 0.1 4.5e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO83679.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO83679.1 - 0.00045 20.1 0.0 0.56 10.0 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family MARVEL PF01284.18 GAO83680.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain m04gp34like PF12216.3 GAO83680.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein Cep57_MT_bd PF06657.8 GAO83681.1 - 4.7e-29 100.1 1.2 4.7e-29 100.1 0.9 2.9 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 GAO83681.1 - 6.3e-21 74.1 11.9 6.3e-21 74.1 8.3 4.8 5 0 0 5 5 5 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 GAO83681.1 - 0.0005 19.7 1.0 0.0005 19.7 0.7 4.0 5 0 0 5 5 5 1 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 GAO83681.1 - 0.042 13.5 9.7 0.071 12.8 0.3 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain DAHP_synth_2 PF01474.11 GAO83682.1 - 1.9e-199 662.5 0.0 2.2e-199 662.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family LytR_C PF13399.1 GAO83683.1 - 0.28 11.5 1.8 0.53 10.7 1.3 1.6 1 1 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Remorin_N PF03766.8 GAO83683.1 - 1.2 9.0 8.3 1 9.2 0.7 2.4 2 0 0 2 2 2 0 Remorin, N-terminal region MFS_1 PF07690.11 GAO83684.1 - 1e-30 106.6 22.0 1.7e-30 105.9 15.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PLA2_B PF01735.13 GAO83686.1 - 2e-201 669.4 3.3 2.4e-201 669.1 2.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain adh_short_C2 PF13561.1 GAO83687.1 - 1.2e-27 97.2 0.0 1.6e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO83687.1 - 6.4e-26 91.2 1.0 8e-26 90.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO83687.1 - 1.4e-14 54.1 0.4 1.9e-14 53.7 0.3 1.1 1 0 0 1 1 1 1 KR domain zf-ribbon_3 PF13248.1 GAO83688.1 - 0.015 14.4 5.8 0.026 13.7 4.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain U79_P34 PF03064.11 GAO83688.1 - 0.068 12.6 6.4 0.085 12.3 4.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC27 PF09507.5 GAO83688.1 - 1.2 8.2 17.2 0.12 11.5 7.9 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF4139 PF13598.1 GAO83688.1 - 7.8 5.6 9.3 1.1 8.4 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) DUF1215 PF06744.7 GAO83689.1 - 0.12 11.9 0.6 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) DHDPS PF00701.17 GAO83692.1 - 1.6e-41 141.7 0.0 2e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribophorin_II PF05817.9 GAO83694.1 - 8.2e-18 63.9 0.1 1e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TFIIF_alpha PF05793.7 GAO83697.1 - 0.57 8.4 6.9 0.92 7.7 4.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) His_Phos_2 PF00328.17 GAO83698.1 - 4.8e-62 210.2 0.0 5.6e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_2 PF07716.10 GAO83699.1 - 0.16 11.8 9.9 0.32 10.8 6.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper SGL PF08450.7 GAO83700.1 - 1.1e-78 263.9 0.0 1.4e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 GAO83700.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Aldedh PF00171.17 GAO83701.1 - 1.2e-187 623.9 0.2 1.3e-187 623.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IPI_T4 PF11634.3 GAO83701.1 - 0.022 14.6 0.1 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 EVE PF01878.13 GAO83702.1 - 6.2e-53 178.6 0.2 8e-53 178.3 0.1 1.1 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 GAO83702.1 - 0.00038 19.8 36.8 0.029 13.9 2.6 4.8 4 0 0 4 4 4 3 AT hook motif CATSPERG PF15064.1 GAO83702.1 - 0.022 12.5 0.0 0.028 12.1 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma AhpC-TSA PF00578.16 GAO83703.1 - 3.3e-34 117.2 0.0 6e-34 116.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 GAO83703.1 - 2.8e-17 62.0 0.2 4.4e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 GAO83703.1 - 4.5e-14 52.2 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_4 PF13418.1 GAO83704.1 - 7.7e-21 73.6 3.3 7.2e-10 38.4 0.0 5.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAO83704.1 - 5.6e-19 67.7 6.1 2.6e-10 40.1 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO83704.1 - 7.3e-11 41.7 5.9 0.00046 20.0 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAO83704.1 - 4.3e-10 38.9 0.0 0.056 13.0 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 GAO83704.1 - 1.8e-09 37.3 5.5 0.0048 17.0 0.0 5.3 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAO83704.1 - 2.8e-09 36.3 3.8 0.001 18.7 0.0 5.1 4 1 0 4 4 4 3 Kelch motif BTB PF00651.26 GAO83704.1 - 0.047 13.6 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain RAG2 PF03089.9 GAO83704.1 - 0.09 11.4 0.0 0.3 9.7 0.0 1.8 1 1 0 1 1 1 0 Recombination activating protein 2 CTP_transf_2 PF01467.21 GAO83706.1 - 0.0015 18.5 2.2 0.022 14.8 1.5 2.5 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 GAO83706.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase WD40 PF00400.27 GAO83707.1 - 2.5e-23 81.0 12.7 4.3e-09 35.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat KduI PF04962.7 GAO83707.1 - 0.03 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Acyl_transf_3 PF01757.17 GAO83708.1 - 1e-34 119.9 35.1 1.6e-34 119.2 24.3 1.3 1 0 0 1 1 1 1 Acyltransferase family MMgT PF10270.4 GAO83708.1 - 0.17 12.3 2.7 0.36 11.2 0.0 2.7 3 0 0 3 3 3 0 Membrane magnesium transporter Lipid_DES PF08557.5 GAO83709.1 - 0.023 13.9 2.0 0.097 11.9 0.8 2.1 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) mRNA_triPase PF02940.10 GAO83710.1 - 8.5e-60 202.1 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PepSY PF03413.14 GAO83710.1 - 0.11 13.1 0.0 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain CTD PF12815.2 GAO83711.1 - 2.8e-29 102.0 44.7 1.3e-27 96.6 21.8 3.6 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 GAO83711.1 - 1.9e-25 88.3 0.0 3.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 GAO83711.1 - 1.4e-17 64.0 10.4 1.4e-17 64.0 7.2 4.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 GAO83711.1 - 3.2e-12 45.6 16.1 7.8e-05 22.2 0.0 4.8 5 0 0 5 5 5 3 KOW motif Acyl-CoA_dh_1 PF00441.19 GAO83712.1 - 5.7e-42 143.3 1.3 8.6e-42 142.7 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO83712.1 - 9.7e-21 73.0 0.1 1.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 GAO83712.1 - 1.1e-18 66.8 0.3 2e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 GAO83712.1 - 2.5e-17 63.4 0.0 6.7e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAO83712.1 - 4.6e-09 36.6 0.1 8.1e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 GAO83713.1 - 8.8e-39 129.6 17.7 1.4e-09 37.6 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAO83713.1 - 2.1e-19 69.5 1.0 2.4e-12 46.9 0.0 4.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 GAO83713.1 - 2.1e-08 33.5 0.2 3.3 8.0 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 GAO83713.1 - 5e-07 30.0 6.0 6.8e-06 26.4 0.0 5.0 4 1 1 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.11 GAO83713.1 - 0.055 13.9 2.0 0.88 10.2 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Filament PF00038.16 GAO83714.1 - 0.0045 16.4 4.2 0.0045 16.4 2.9 2.3 2 0 0 2 2 2 2 Intermediate filament protein FliD_C PF07195.7 GAO83714.1 - 0.91 8.7 4.3 14 4.8 0.1 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus GrpE PF01025.14 GAO83714.1 - 1.9 7.9 10.4 1.9 8.0 1.3 2.4 2 0 0 2 2 2 0 GrpE DUF1664 PF07889.7 GAO83714.1 - 2.7 7.8 6.8 0.78 9.5 1.5 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 GAO83714.1 - 3.2 6.9 8.5 0.45 9.7 1.0 2.4 3 0 0 3 3 3 0 Allexivirus 40kDa protein IFP_35_N PF07334.8 GAO83714.1 - 4.6 7.2 8.1 3.5 7.6 1.9 3.0 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Viral_P18 PF04521.8 GAO83714.1 - 5.1 6.5 10.1 11 5.5 0.0 3.0 3 1 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Abhydrolase_5 PF12695.2 GAO83715.1 - 4.2e-08 33.0 0.0 7.7e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO83715.1 - 5.3e-06 26.4 0.1 0.00011 22.2 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO83715.1 - 0.13 11.4 0.2 0.78 8.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF726 PF05277.7 GAO83715.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 GAO83715.1 - 0.61 9.6 5.2 3.8 6.9 2.0 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF3336 PF11815.3 GAO83716.1 - 1.6e-47 160.6 1.1 2.8e-47 159.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAO83716.1 - 4.9e-21 75.5 0.0 1e-20 74.5 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PMI_typeI PF01238.16 GAO83718.1 - 5.9e-67 226.2 0.0 4.8e-65 219.9 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 GAO83718.1 - 0.091 12.2 0.0 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Cupin domain SIMPL PF04402.9 GAO83719.1 - 6.9e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SKG6 PF08693.5 GAO83719.1 - 0.015 14.5 0.6 0.03 13.6 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.7 GAO83719.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Med8 PF10232.4 GAO83721.1 - 5.5e-54 183.0 0.0 7.8e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TMEM154 PF15102.1 GAO83721.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.10 GAO83721.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.1 GAO83721.1 - 0.096 13.0 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Myc_N PF01056.13 GAO83721.1 - 3.4 6.7 9.5 0.079 12.1 1.2 2.2 3 0 0 3 3 3 0 Myc amino-terminal region SKG6 PF08693.5 GAO83721.1 - 4.2 6.7 5.7 14 5.1 4.0 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain PQ-loop PF04193.9 GAO83722.1 - 1.1e-22 79.3 2.9 1.7e-11 43.4 0.6 2.6 2 0 0 2 2 2 2 PQ loop repeat DoxX_3 PF13781.1 GAO83722.1 - 0.093 13.1 0.7 0.093 13.1 0.5 2.1 2 1 0 2 2 2 0 DoxX-like family DUF4418 PF14387.1 GAO83722.1 - 5.5 6.7 6.9 0.4 10.4 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF1290 PF06947.7 GAO83722.1 - 9.9 6.1 9.3 0.19 11.6 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1290) UbiA PF01040.13 GAO83723.1 - 3.9e-28 98.3 20.6 5.6e-28 97.8 14.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family tRNA-synt_2 PF00152.15 GAO83724.1 - 6.1e-103 344.1 0.0 8.5e-103 343.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_1b PF00579.20 GAO83725.1 - 9.8e-73 244.8 0.0 1.6e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 GAO83725.1 - 0.011 15.1 0.1 4 6.9 0.1 2.5 2 0 0 2 2 2 0 S4 domain MutS_V PF00488.16 GAO83726.1 - 4.1e-81 271.8 0.0 6.8e-81 271.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO83726.1 - 2.9e-52 177.4 0.1 4.9e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAO83726.1 - 7.2e-33 112.9 0.1 2.2e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 GAO83726.1 - 2e-14 53.5 0.5 4.4e-14 52.4 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAO83726.1 - 3e-14 53.2 0.0 8.2e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II Shugoshin_C PF07557.6 GAO83726.1 - 0.011 15.1 0.4 0.028 13.8 0.2 1.7 1 0 0 1 1 1 0 Shugoshin C terminus AAA_23 PF13476.1 GAO83726.1 - 0.013 15.8 4.3 0.021 15.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 GAO83726.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 GAO83726.1 - 0.062 13.2 1.1 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SPT6_acidic PF14632.1 GAO83726.1 - 0.93 9.7 16.5 4 7.6 2.1 2.8 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Peptidase_M28 PF04389.12 GAO83728.1 - 6.9e-34 117.1 0.1 9.7e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.9 GAO83729.1 - 6.3e-16 58.1 15.4 8.8e-11 41.6 3.7 4.5 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 GAO83729.1 - 4.5e-09 35.8 0.9 4.5e-09 35.8 0.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4341) LigD_N PF13298.1 GAO83730.1 - 2.3e-26 91.9 0.1 2.6e-25 88.5 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) Raffinose_syn PF05691.7 GAO83731.1 - 1.9e-51 174.5 0.3 5.4e-44 149.8 0.0 2.7 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 GAO83731.1 - 0.00064 18.5 0.4 0.001 17.8 0.3 1.2 1 0 0 1 1 1 1 Melibiase ADH_zinc_N PF00107.21 GAO83732.1 - 1.7e-24 85.8 0.2 2.7e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO83732.1 - 1.4e-13 50.5 0.0 3.6e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO83732.1 - 3.6e-13 50.5 0.0 9.1e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAO83732.1 - 0.00055 19.5 0.1 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 GAO83732.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 GAO83732.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aldo_ket_red PF00248.16 GAO83734.1 - 6.9e-57 192.4 0.0 8.7e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.19 GAO83736.1 - 2.2e-14 53.2 0.1 3.8e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO83736.1 - 2.1e-05 24.5 0.2 3.8e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO83736.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAO83736.1 - 0.025 14.6 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO83736.1 - 0.041 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RPT PF13446.1 GAO83736.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein PIG-U PF06728.8 GAO83737.1 - 7.5e-120 400.2 23.2 8.6e-120 400.0 16.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 GAO83738.1 - 1.6e-113 378.6 0.0 1.6e-113 378.6 0.0 2.3 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 GAO83738.1 - 8.6e-09 35.4 0.0 9.9e-08 32.0 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Nop14 PF04147.7 GAO83738.1 - 8.3 4.1 40.7 17 3.1 28.2 1.5 1 0 0 1 1 1 0 Nop14-like family RRN9 PF10680.4 GAO83739.1 - 1.9e-24 85.1 0.7 5.7e-24 83.6 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 GAO83739.1 - 0.057 13.7 0.6 0.26 11.7 0.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Aldedh PF00171.17 GAO83740.1 - 3.4e-162 539.9 0.1 3.8e-162 539.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO83740.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) His_Phos_2 PF00328.17 GAO83741.1 - 5.8e-34 117.9 0.0 7.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_L36 PF00444.13 GAO83741.1 - 2e-10 40.4 6.0 4.8e-10 39.2 4.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L36 Ank_2 PF12796.2 GAO83742.1 - 4.1e-23 81.5 0.0 5.9e-07 29.7 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO83742.1 - 2.8e-13 48.7 0.1 0.0098 16.0 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 GAO83742.1 - 7.7e-13 47.5 0.1 0.039 13.7 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAO83742.1 - 5.9e-07 29.8 0.5 0.91 10.1 0.0 4.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO83742.1 - 1.2e-05 25.3 1.7 5.8 7.3 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Nucleoplasmin PF03066.10 GAO83744.1 - 0.19 11.2 3.4 0.44 10.0 1.8 1.8 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 GAO83744.1 - 2.5 6.0 5.0 0.2 9.6 0.1 1.5 2 0 0 2 2 2 0 CDC45-like protein PALP PF00291.20 GAO83745.1 - 3.4e-72 243.2 0.6 4.5e-72 242.8 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 GAO83745.1 - 4.8e-46 154.2 0.0 1e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 GAO83746.1 - 8e-27 92.7 0.1 1.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2681 PF10883.3 GAO83746.1 - 0.05 13.8 1.4 0.11 12.7 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) SPT16 PF08644.6 GAO83746.1 - 0.055 13.3 0.3 0.087 12.6 0.2 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) MAS20 PF02064.10 GAO83746.1 - 1.9 8.3 4.7 0.56 10.1 0.9 1.9 1 1 1 2 2 2 0 MAS20 protein import receptor PBP PF01161.15 GAO83747.1 - 6.9e-15 55.1 0.1 7.9e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GTP_EFTU PF00009.22 GAO83748.1 - 2.1e-56 190.3 0.1 3.8e-56 189.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAO83748.1 - 5.9e-32 109.3 0.0 1.3e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAO83748.1 - 2.4e-30 104.5 0.0 5e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAO83748.1 - 1.2e-23 82.7 0.0 2.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO83748.1 - 1.3e-12 47.6 0.7 2.6e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Abhydrolase_5 PF12695.2 GAO83749.1 - 2.6e-09 36.9 0.0 5.9e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO83749.1 - 3.7e-09 36.8 0.3 7.1e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAO83749.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAO83749.1 - 0.013 15.3 0.1 0.087 12.6 0.1 2.1 1 1 0 1 1 1 0 Putative lysophospholipase Na_Pi_cotrans PF02690.10 GAO83749.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter Abhydrolase_1 PF00561.15 GAO83749.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TLD PF07534.11 GAO83751.1 - 3.5e-24 85.3 0.0 5.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 TLD NMT_C PF02799.10 GAO83752.1 - 8.6e-79 263.3 0.0 1.4e-78 262.6 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 GAO83752.1 - 2.8e-78 261.1 0.1 4.8e-78 260.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 GAO83752.1 - 3.8e-06 26.7 0.0 3.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO83752.1 - 0.0022 18.1 0.2 0.0095 16.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF427 PF04248.7 GAO83752.1 - 0.024 14.2 0.1 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) DUF3485 PF11984.3 GAO83752.1 - 0.027 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Mur_ligase_M PF08245.7 GAO83753.1 - 2.7e-06 27.5 0.3 0.00022 21.3 0.2 3.2 1 1 0 1 1 1 1 Mur ligase middle domain DUF2188 PF09954.4 GAO83753.1 - 0.06 13.2 0.4 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Syja_N PF02383.13 GAO83754.1 - 2.1e-92 309.3 0.0 2.6e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 GAO83755.1 - 3.5e-59 198.8 0.1 4e-59 198.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO83755.1 - 6.8e-20 71.7 0.1 1.2e-19 70.9 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 GAO83755.1 - 2.8e-14 52.7 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAO83755.1 - 1.3e-07 31.0 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAO83755.1 - 2.5e-07 30.3 0.0 4.5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAO83755.1 - 6.3e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAO83755.1 - 0.0043 17.1 0.0 0.71 10.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain MCR_beta PF02241.13 GAO83755.1 - 0.0047 16.1 0.0 1.3 8.1 0.0 2.1 1 1 1 2 2 2 2 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF258 PF03193.11 GAO83755.1 - 0.03 13.5 0.3 0.1 11.7 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAO83755.1 - 0.031 14.2 0.2 0.089 12.7 0.2 1.9 1 1 1 2 2 2 0 AAA ATPase domain Shikimate_DH PF01488.15 GAO83755.1 - 0.031 14.3 0.0 0.11 12.5 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_14 PF13173.1 GAO83755.1 - 0.14 12.0 0.1 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mitofilin PF09731.4 GAO83756.1 - 8.6e-155 516.6 21.2 1.1e-154 516.3 14.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Orn_Arg_deC_N PF02784.11 GAO83758.1 - 7.5e-77 257.9 0.0 1.2e-76 257.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAO83758.1 - 1.3e-31 108.7 0.0 2.6e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain cobW PF02492.14 GAO83759.1 - 9.2e-39 132.7 0.0 1.3e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 GAO83759.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAO83759.1 - 0.014 15.1 0.1 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAO83759.1 - 0.024 14.7 0.0 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO83759.1 - 0.031 14.5 0.1 0.085 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAO83759.1 - 0.039 13.4 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 GAO83759.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO83759.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CobW_C PF07683.9 GAO83759.1 - 0.088 12.5 0.0 0.88 9.3 0.0 2.3 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Pox_A32 PF04665.7 GAO83759.1 - 0.096 11.9 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Viral_helicase1 PF01443.13 GAO83759.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Troponin-I_N PF11636.3 GAO83759.1 - 0.16 11.7 1.2 0.36 10.5 0.8 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 Acetyltransf_3 PF13302.1 GAO83760.1 - 3.1e-18 66.3 0.0 4.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO83760.1 - 0.008 16.1 1.0 0.048 13.6 0.7 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 GAO83760.1 - 0.021 14.6 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO83760.1 - 0.041 13.6 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein DNA_pol_E_B PF04042.11 GAO83761.1 - 6.5e-52 175.8 0.0 8.7e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Abhydrolase_5 PF12695.2 GAO83761.1 - 0.15 11.7 0.2 0.34 10.6 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mid2 PF04478.7 GAO83762.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.15 GAO83762.1 - 0.017 14.7 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Yip1 PF04893.12 GAO83762.1 - 0.031 13.7 0.5 0.05 13.1 0.0 1.5 2 0 0 2 2 2 0 Yip1 domain SKG6 PF08693.5 GAO83762.1 - 0.07 12.4 1.0 0.16 11.3 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MSP1_C PF07462.6 GAO83762.1 - 3.6 5.8 4.7 6 5.1 3.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NMO PF03060.10 GAO83763.1 - 3e-74 250.1 0.6 3.5e-74 249.9 0.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAO83763.1 - 1.3e-07 30.8 0.0 2e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAO83763.1 - 0.0042 15.9 2.2 0.0074 15.1 1.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.4 GAO83764.1 - 5e-103 344.4 54.7 5e-103 344.4 37.9 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.1 GAO83764.1 - 0.0044 16.4 15.0 0.0044 16.4 10.4 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF4201) YliH PF10799.3 GAO83764.1 - 0.97 9.1 8.5 0.2 11.3 1.0 2.8 2 1 0 2 2 2 0 Biofilm formation protein (YliH/bssR) HlyD PF00529.15 GAO83764.1 - 7.7 5.7 21.1 5.9 6.0 4.4 2.3 2 0 0 2 2 2 0 HlyD family secretion protein M16C_assoc PF08367.6 GAO83765.1 - 1.2e-53 181.4 0.0 2.2e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 GAO83765.1 - 2.9e-22 79.2 0.0 2.8e-11 43.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAO83765.1 - 1.9e-09 37.4 0.0 5.7e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) MOR2-PAG1_C PF14225.1 GAO83765.1 - 0.12 12.1 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Zn_clus PF00172.13 GAO83766.1 - 0.00098 18.9 2.3 0.0017 18.1 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 GAO83768.1 - 1e-58 197.6 0.0 3.2e-58 196.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAO83768.1 - 0.0026 18.3 0.0 0.0081 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAO83768.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 GAO83768.1 - 0.063 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DSBA PF01323.15 GAO83769.1 - 3.8e-21 75.5 0.0 4.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GSG-1 PF07803.6 GAO83769.1 - 0.09 12.3 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 GSG1-like protein FliG_N PF14842.1 GAO83769.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 FliG N-terminal domain SusD PF07980.6 GAO83770.1 - 0.00053 19.5 0.1 0.00064 19.3 0.0 1.1 1 0 0 1 1 1 1 SusD family Glyco_hydro_61 PF03443.9 GAO83771.1 - 1.1e-83 280.3 0.2 1.3e-83 280.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2240 PF09999.4 GAO83771.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Ribosomal_L38e PF01781.13 GAO83772.1 - 3.7e-31 106.6 2.4 6.9e-31 105.8 1.6 1.5 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1470 PF07336.6 GAO83773.1 - 0.018 15.3 2.0 0.018 15.3 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) Ish1 PF10281.4 GAO83773.1 - 0.079 13.0 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein SAP PF02037.22 GAO83773.1 - 0.12 11.8 0.1 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 SAP domain NTF2 PF02136.15 GAO83774.1 - 4.8e-10 39.8 1.0 8.5e-10 39.0 0.7 1.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 GAO83774.1 - 2.3e-05 24.2 0.1 0.00026 20.7 0.1 2.0 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 GAO83775.1 - 5.2e-106 354.5 0.0 1.8e-105 352.8 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAO83775.1 - 3.4e-20 71.6 0.1 4.5e-11 41.4 0.0 3.7 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 GAO83775.1 - 1.9e-10 40.3 0.0 0.00018 20.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 GAO83775.1 - 4.9e-06 26.3 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PALP PF00291.20 GAO83776.1 - 1e-48 166.1 0.7 1.3e-48 165.7 0.1 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.17 GAO83777.1 - 7.4e-41 135.8 12.3 8.7e-10 37.5 0.6 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4614 PF15391.1 GAO83777.1 - 0.011 15.5 0.1 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TPR_14 PF13428.1 GAO83777.1 - 0.049 14.2 0.3 1.7 9.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO83777.1 - 0.07 13.4 0.2 0.43 10.9 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83777.1 - 0.078 13.6 0.1 0.42 11.3 0.0 2.3 2 2 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 GAO83778.1 - 7.6e-23 80.7 0.4 1.5e-21 76.4 0.3 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain GHMP_kinases_N PF00288.21 GAO83779.1 - 8e-18 64.2 0.0 1.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAO83779.1 - 2.8e-08 33.8 0.1 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 GAO83779.1 - 0.007 15.6 0.1 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.16 GAO83780.1 - 5e-59 199.8 31.9 6.4e-59 199.5 22.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 GAO83781.1 - 3e-79 266.4 23.8 4e-79 266.0 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.8 GAO83782.1 - 2.7e-36 124.1 0.1 3e-36 123.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 GAO83782.1 - 0.073 12.9 0.3 0.096 12.5 0.2 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange LSM PF01423.17 GAO83783.1 - 2.7e-18 65.2 0.0 3.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 GAO83784.1 - 8.4e-23 79.9 0.0 1.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAO83784.1 - 2.5e-21 75.1 0.1 7.2e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Kelch_5 PF13854.1 GAO83785.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Kelch motif COesterase PF00135.23 GAO83786.1 - 8.7e-60 202.9 0.0 1e-59 202.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO83786.1 - 0.11 12.0 0.1 2.2 7.8 0.1 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold PPR PF01535.15 GAO83786.1 - 0.12 12.3 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 PPR repeat CPSase_L_D2 PF02786.12 GAO83787.1 - 1.5e-81 272.7 0.1 2.3e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 GAO83787.1 - 6.3e-66 221.5 0.0 1.1e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 GAO83787.1 - 8.2e-38 128.8 0.1 1.7e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAO83787.1 - 1.5e-30 105.3 0.0 4.4e-30 103.8 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 GAO83787.1 - 2.1e-27 96.2 0.0 4.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 GAO83787.1 - 7.6e-21 74.6 0.1 1.9e-20 73.3 0.1 1.7 2 0 0 2 2 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAO83787.1 - 4e-19 68.0 6.0 4.3e-19 67.9 2.4 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAO83787.1 - 5.7e-18 64.7 0.0 2.3e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 GAO83787.1 - 9e-11 41.2 4.8 8.5e-07 28.5 0.1 3.6 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 GAO83787.1 - 2.1e-10 40.3 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAO83787.1 - 7.9e-08 31.8 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAO83787.1 - 2e-06 27.3 0.0 1.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 GAO83787.1 - 1.7e-05 24.1 0.1 0.012 14.7 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 GAO83787.1 - 2.2e-05 24.7 0.3 0.0023 18.2 0.1 3.4 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 GAO83787.1 - 4.4e-05 22.9 0.2 0.0022 17.3 0.0 2.5 2 0 0 2 2 2 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 GAO83787.1 - 6.3e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 GAO83787.1 - 0.026 14.2 0.2 0.067 12.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 GAO83787.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 GAO83787.1 - 0.053 13.2 0.5 0.28 10.8 0.3 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.6 GAO83787.1 - 0.074 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 GAO83787.1 - 0.15 11.7 1.8 0.75 9.5 1.3 2.2 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AICARFT_IMPCHas PF01808.13 GAO83788.1 - 6.4e-108 360.5 0.0 8.7e-108 360.1 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme INSIG PF07281.7 GAO83788.1 - 3.6e-86 287.4 2.0 5.5e-86 286.8 1.4 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) MGS PF02142.17 GAO83788.1 - 7.9e-25 86.6 0.0 1.5e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DEAD PF00270.24 GAO83790.1 - 7.5e-46 155.7 0.0 1.3e-44 151.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO83790.1 - 3.2e-28 97.4 0.1 6.9e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO83790.1 - 0.015 14.0 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 GAO83790.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 GAO83790.1 - 0.13 10.5 0.0 0.24 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 GAO83790.1 - 0.15 11.0 0.1 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1633 PF07794.6 GAO83790.1 - 0.84 7.5 4.8 1.3 6.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Pro_isomerase PF00160.16 GAO83791.1 - 2.5e-46 157.6 0.2 3.4e-46 157.2 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 GAO83792.1 - 1.2e-21 77.1 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAO83792.1 - 0.063 11.8 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) WD40 PF00400.27 GAO83793.1 - 2.9e-31 106.1 21.2 2.4e-07 30.3 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 GAO83793.1 - 3.6e-22 78.1 0.1 7.2e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Zw10 PF06248.8 GAO83794.1 - 5.1e-13 48.0 1.8 5.3e-10 38.0 0.2 2.7 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 GAO83794.1 - 4e-08 32.7 0.4 4e-08 32.7 0.2 2.8 3 1 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 GAO83794.1 - 0.03 14.7 1.6 0.18 12.2 0.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Peptidase_M16_C PF05193.16 GAO83795.1 - 2.3e-18 66.5 0.0 3.1e-13 49.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAO83795.1 - 2.6e-05 23.9 0.0 8.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2205 PF10224.4 GAO83795.1 - 0.036 13.6 1.0 0.085 12.4 0.7 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Nucleoplasmin PF03066.10 GAO83795.1 - 0.27 10.7 7.7 0.59 9.6 5.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAO83795.1 - 0.32 8.8 3.2 0.45 8.3 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.5 GAO83796.1 - 1.7e-08 33.6 2.8 1.7e-08 33.6 1.9 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.7 GAO83796.1 - 1e-06 28.2 1.8 1.9e-06 27.3 1.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 GAO83796.1 - 0.00096 18.8 0.4 0.0018 18.0 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF1049 PF06305.6 GAO83796.1 - 0.021 14.2 0.3 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4448 PF14610.1 GAO83796.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 GAO83796.1 - 0.031 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family SLAC1 PF03595.12 GAO83796.1 - 0.056 12.0 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel TMEM51 PF15345.1 GAO83796.1 - 0.062 12.9 0.7 0.1 12.2 0.4 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Med3 PF11593.3 GAO83796.1 - 1.3 8.2 9.5 2.4 7.3 6.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L34 PF00468.12 GAO83797.1 - 1.5e-17 62.9 12.0 2.4e-17 62.2 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 DUF566 PF04484.7 GAO83797.1 - 0.78 9.1 8.8 0.96 8.9 6.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) RNA_polI_A14 PF08203.6 GAO83798.1 - 0.0093 16.1 0.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 YL1 PF05764.8 GAO83798.1 - 0.04 13.5 10.7 0.052 13.1 7.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 GAO83798.1 - 0.66 7.8 12.4 0.73 7.6 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 GAO83798.1 - 1 8.4 9.1 1.5 7.8 6.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Sec62 PF03839.11 GAO83798.1 - 6 6.1 5.9 7.9 5.8 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.9 GAO83798.1 - 9.8 4.0 12.0 12 3.7 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M48 PF01435.13 GAO83799.1 - 4.7e-52 176.7 0.0 6.7e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 GAO83799.1 - 0.0084 15.3 1.6 0.02 14.2 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 GAO83799.1 - 0.078 11.9 1.3 0.56 9.1 0.8 2.0 1 1 0 1 1 1 0 BlaR1 peptidase M56 GTP_EFTU PF00009.22 GAO83800.1 - 7.6e-38 129.8 0.0 1.2e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 GAO83800.1 - 7.7e-37 125.2 0.2 1.7e-36 124.0 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 GAO83800.1 - 1.7e-12 47.2 0.2 4e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO83800.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Connexin_CCC PF10582.4 GAO83800.1 - 0.26 11.1 0.7 0.59 9.9 0.5 1.5 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain WD40 PF00400.27 GAO83801.1 - 2.4e-07 30.3 0.1 0.045 13.6 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HSA PF07529.8 GAO83802.1 - 6.3e-26 89.9 0.3 6.3e-26 89.9 0.2 3.8 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 GAO83802.1 - 3e-16 59.2 1.4 6.5e-16 58.1 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO83802.1 - 0.008 16.2 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain G-patch_2 PF12656.2 GAO83803.1 - 1.5e-29 101.6 0.0 8.7e-29 99.1 0.0 2.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 GAO83803.1 - 0.00021 20.9 0.3 0.00049 19.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.27 GAO83804.1 - 1.2e-73 240.5 28.7 1.6e-09 37.2 0.2 12.4 11 2 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 GAO83804.1 - 6.3e-45 152.2 0.1 9.7e-45 151.6 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 GAO83804.1 - 4.6e-10 38.2 6.3 0.13 10.4 0.2 5.6 2 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO83804.1 - 0.00013 20.8 2.0 5.8 5.5 0.0 5.3 4 2 1 6 6 6 2 Nup133 N terminal like DUF3312 PF11768.3 GAO83804.1 - 0.13 10.4 0.0 0.39 8.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF2127 PF09900.4 GAO83805.1 - 0.01 15.8 1.0 0.79 9.7 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) UCH PF00443.24 GAO83806.1 - 3.4e-24 85.3 0.0 9.8e-23 80.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAO83806.1 - 8.8e-11 41.7 0.1 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Proteasome PF00227.21 GAO83807.1 - 1.4e-37 128.8 0.0 1.7e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.15 GAO83807.1 - 0.13 11.7 0.1 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) WD40 PF00400.27 GAO83808.1 - 8.8e-36 120.5 9.7 1.4e-08 34.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAO83808.1 - 0.00053 18.2 0.2 0.51 8.3 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 zf-ribbon_3 PF13248.1 GAO83809.1 - 0.21 10.8 1.0 0.51 9.6 0.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain 2OG-FeII_Oxy_3 PF13640.1 GAO83810.1 - 0.00066 20.1 0.0 0.0019 18.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 GAO83810.1 - 0.0063 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe dioxygenase NatB_MDM20 PF09797.4 GAO83811.1 - 1.4e-109 366.2 0.0 2.4e-109 365.4 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ribosomal_L36e PF01158.13 GAO83811.1 - 7.4e-37 125.2 4.9 7.4e-37 125.2 3.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L36e TPR_19 PF14559.1 GAO83811.1 - 0.00015 22.0 6.0 0.023 14.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO83811.1 - 0.0037 17.8 3.7 0.099 13.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO83811.1 - 0.014 15.9 0.9 62 4.6 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TUG-UBL1 PF11470.3 GAO83812.1 - 5.4e-25 87.0 0.3 1.6e-24 85.6 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 GAO83812.1 - 8e-06 25.8 0.0 5.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 UBX domain Rad60-SLD PF11976.3 GAO83812.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RBD PF02196.10 GAO83812.1 - 0.033 13.9 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain PAT1 PF09770.4 GAO83812.1 - 1.3 7.2 8.8 1.9 6.6 6.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Proteasome PF00227.21 GAO83813.1 - 6.6e-42 142.9 0.0 7.6e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EHN PF06441.7 GAO83814.1 - 3.9e-36 123.3 0.1 1.3e-34 118.4 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAO83814.1 - 4.5e-13 49.6 5.4 1.3e-12 48.0 3.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO83814.1 - 1.4e-10 41.1 0.1 2.2e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold HATPase_c PF02518.21 GAO83815.1 - 1e-19 70.2 0.0 1.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO83815.1 - 2.9e-14 53.0 0.2 3.7e-07 30.1 0.0 3.5 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 GAO83815.1 - 1.1e-05 25.3 0.0 3.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain EMP24_GP25L PF01105.19 GAO83816.1 - 1.6e-49 168.0 0.0 2e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Meth_synt_2 PF01717.13 GAO83819.1 - 4.6e-145 482.6 0.0 1.7e-139 464.3 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAO83819.1 - 8.1e-121 403.0 0.0 5.2e-108 360.9 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Ufd2P_core PF10408.4 GAO83820.1 - 3.1e-203 676.5 3.4 3.7e-203 676.2 2.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 GAO83820.1 - 4.1e-27 93.9 1.4 9.5e-27 92.7 0.2 2.3 2 0 0 2 2 2 1 U-box domain Steroid_dh PF02544.11 GAO83820.1 - 5.4e-14 52.2 0.1 4.7e-05 23.1 0.0 3.8 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 GAO83820.1 - 0.0063 15.8 1.7 0.25 10.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1295) DUF1977 PF09320.6 GAO83821.1 - 8.8e-31 106.3 0.1 1.6e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 GAO83821.1 - 6.9e-24 83.3 0.9 1.2e-23 82.5 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 GAO83821.1 - 0.12 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 GAO83822.1 - 8.4e-06 26.0 0.0 1.1e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) CTP_transf_2 PF01467.21 GAO83823.1 - 0.00022 21.2 0.0 0.0023 18.0 0.0 2.3 2 1 1 3 3 3 1 Cytidylyltransferase CENP-T PF15511.1 GAO83824.1 - 0.004 16.4 7.4 0.0046 16.2 5.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 GAO83824.1 - 0.0048 14.9 16.6 0.006 14.5 11.5 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 GAO83824.1 - 0.0054 15.2 12.0 0.0073 14.8 8.3 1.3 1 0 0 1 1 1 1 Daxx Family Astro_capsid PF03115.9 GAO83824.1 - 0.042 12.1 8.0 0.062 11.5 5.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PPP4R2 PF09184.6 GAO83824.1 - 0.059 12.9 16.6 0.078 12.5 11.5 1.1 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.11 GAO83824.1 - 0.11 11.4 11.1 0.15 10.9 7.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 GAO83824.1 - 0.13 11.6 10.9 0.21 10.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2722 PF10846.3 GAO83824.1 - 1.9 7.4 7.5 2.7 6.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Retinal PF15449.1 GAO83824.1 - 2.1 5.9 6.7 2.7 5.5 4.6 1.1 1 0 0 1 1 1 0 Retinal protein CobT PF06213.7 GAO83824.1 - 5.2 6.1 22.8 7.2 5.6 15.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ydc2-catalyt PF09159.5 GAO83825.1 - 3.9e-94 315.1 0.0 4.7e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 GAO83825.1 - 6.8e-08 31.8 0.2 1.4e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 GAO83825.1 - 0.0009 19.1 0.0 0.97 9.3 0.0 3.1 3 0 0 3 3 3 1 Poxvirus A22 protein Tcp11 PF05794.8 GAO83826.1 - 4.4e-141 470.5 0.0 5.6e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_S10 PF00450.17 GAO83827.1 - 2.7e-78 263.9 0.0 1.3e-77 261.7 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAO83827.1 - 5e-08 33.1 0.0 1.4e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family SOG2 PF10428.4 GAO83828.1 - 8.5e-137 456.4 0.8 8.5e-137 456.4 0.6 2.1 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 GAO83828.1 - 1.5e-17 62.8 14.3 6.7e-08 31.9 0.8 3.8 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO83828.1 - 1.3e-13 50.4 14.3 2e-07 30.6 0.6 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAO83828.1 - 1.1e-10 40.0 5.3 0.019 14.9 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 GAO83828.1 - 4.5e-06 25.9 3.8 1.9 9.0 0.0 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 GAO83828.1 - 0.07 13.2 7.1 11 6.4 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 GAO83829.1 - 4e-90 301.3 3.7 4.5e-90 301.1 2.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_3 PF13812.1 GAO83830.1 - 3.8e-07 29.8 0.2 1.5 9.2 0.2 5.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAO83830.1 - 9.5e-07 28.7 0.2 0.2 11.6 0.0 4.2 3 2 2 5 5 5 3 PPR repeat family PPR PF01535.15 GAO83830.1 - 2.4e-06 27.1 0.2 0.032 14.1 0.0 3.9 5 0 0 5 5 5 2 PPR repeat Helicase_C PF00271.26 GAO83831.1 - 3.2e-16 58.9 0.0 9.2e-16 57.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO83831.1 - 0.00013 21.5 0.0 0.05 13.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase KH_1 PF00013.24 GAO83832.1 - 1.2e-10 40.8 0.0 3e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 GAO83832.1 - 2.6e-06 26.9 1.6 0.00023 20.7 0.1 3.2 3 0 0 3 3 3 2 KH domain CDK2AP PF09806.4 GAO83832.1 - 1.1 9.4 17.8 4.3 7.5 0.7 2.8 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein ALS_ss_C PF10369.4 GAO83833.1 - 1.7e-19 69.2 0.0 2.9e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 GAO83833.1 - 7.5e-11 41.2 0.1 1.4e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 GAO83833.1 - 3.2e-09 36.4 0.0 5.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 GAO83833.1 - 0.016 14.9 0.1 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 ACT domain LEA_2 PF03168.8 GAO83834.1 - 7.2e-07 29.5 0.4 0.4 11.0 0.0 4.7 5 1 0 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.3 GAO83834.1 - 0.00019 21.4 0.0 0.0025 17.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) OTCace_N PF02729.16 GAO83835.1 - 2.8e-43 146.9 0.1 4.3e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 GAO83835.1 - 1.2e-39 135.6 0.0 1.8e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain HNF-1B_C PF04812.8 GAO83835.1 - 0.012 14.9 0.0 0.033 13.4 0.0 1.6 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus DUF3984 PF13136.1 GAO83836.1 - 1.1e-111 373.2 26.2 2e-111 372.3 18.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Cut8_C PF08559.5 GAO83837.1 - 9.8e-51 171.3 0.0 1.3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 GAO83837.1 - 2.8e-15 55.7 0.5 5.4e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 GAO83837.1 - 7.2e-15 54.7 5.4 1.2e-14 53.9 3.7 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain rRNA_proc-arch PF13234.1 GAO83838.1 - 5.2e-106 353.7 1.3 9.7e-106 352.8 0.9 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 GAO83838.1 - 3.5e-66 221.8 1.9 8e-66 220.6 1.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAO83838.1 - 6.8e-21 74.4 0.1 3.5e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO83838.1 - 7.4e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 GAO83838.1 - 0.0043 15.9 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein COX7C PF02935.11 GAO83839.1 - 7.2e-16 57.7 0.9 7.6e-16 57.6 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 GAO83840.1 - 0 1139.7 0.0 0 1139.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family GHMP_kinases_N PF00288.21 GAO83841.1 - 6.2e-11 42.2 0.5 1.5e-10 40.9 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 GAO83842.1 - 7.3e-79 264.9 0.2 1.5e-74 250.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase DUF3613 PF12266.3 GAO83842.1 - 0.038 13.5 0.1 0.089 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Syntaxin_2 PF14523.1 GAO83843.1 - 2.8e-24 85.0 2.9 2.8e-24 85.0 2.0 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 GAO83843.1 - 1.5e-18 66.1 1.5 6.3e-18 64.2 1.0 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 GAO83843.1 - 0.0019 18.3 1.2 0.0019 18.3 0.8 2.6 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 GAO83843.1 - 0.012 15.2 0.4 0.045 13.3 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.7 GAO83843.1 - 0.3 10.8 3.1 7.9 6.2 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 GAO83843.1 - 0.61 10.5 11.6 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Ndc1_Nup PF09531.5 GAO83844.1 - 1.1e-177 592.1 0.0 1.2e-177 592.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-C2H2_4 PF13894.1 GAO83845.1 - 2.8e-05 24.1 21.0 0.071 13.4 1.7 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO83845.1 - 0.0016 18.6 22.3 0.083 13.2 1.4 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-FCS PF06467.9 GAO83845.1 - 0.014 15.0 2.0 4.6 6.9 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 GAO83845.1 - 0.09 13.1 0.3 0.09 13.1 0.2 3.5 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAO83845.1 - 0.2 11.8 11.2 0.16 12.1 2.9 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 GAO83846.1 - 3.2e-25 88.2 0.0 4.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAO83846.1 - 2.8e-05 23.5 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 GAO83846.1 - 0.0009 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 GAO83846.1 - 0.036 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAO83846.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Vfa1 PF08432.5 GAO83847.1 - 7.4e-68 228.1 14.2 1.3e-67 227.4 9.9 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 4HBT PF03061.17 GAO83847.1 - 0.0015 18.6 0.4 1.1 9.4 0.0 2.8 3 0 0 3 3 3 2 Thioesterase superfamily CDC45 PF02724.9 GAO83847.1 - 0.04 11.9 8.1 0.056 11.4 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein HCMV_UL139 PF12507.3 GAO83847.1 - 0.21 11.7 6.7 0.13 12.4 2.8 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein U79_P34 PF03064.11 GAO83847.1 - 0.77 9.2 13.9 1.4 8.4 9.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FMN_dh PF01070.13 GAO83848.1 - 1.5e-111 372.7 0.0 1.8e-111 372.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAO83848.1 - 0.00011 21.1 0.5 0.00018 20.5 0.4 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAO83848.1 - 0.0024 17.0 1.4 0.0043 16.2 1.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 GAO83848.1 - 0.003 16.5 0.1 0.0045 15.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAO83848.1 - 0.004 16.4 0.4 0.28 10.4 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 GAO83848.1 - 0.031 13.3 0.8 1.1 8.2 0.1 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 GAO83848.1 - 0.23 10.6 1.3 0.68 9.1 0.1 2.0 1 1 1 2 2 2 0 PcrB family Asp PF00026.18 GAO83849.1 - 1.8e-67 227.8 0.6 2.2e-67 227.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO83849.1 - 3.2e-10 40.1 0.3 9.9e-10 38.6 0.1 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAO83849.1 - 0.0012 18.4 0.0 0.083 12.4 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAO83849.1 - 0.0091 16.4 1.8 1.4 9.4 0.0 3.4 3 1 0 3 3 3 1 Aspartyl protease SAP PF02037.22 GAO83850.1 - 1.8e-07 30.5 0.1 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain FMN_dh PF01070.13 GAO83851.1 - 8.9e-112 373.4 0.0 1.1e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAO83851.1 - 6.3e-20 70.7 0.0 1.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAO83851.1 - 2e-05 23.7 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAO83851.1 - 0.0028 16.6 0.0 0.0097 14.8 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 GAO83851.1 - 0.0061 15.6 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 GAO83851.1 - 0.17 10.9 0.1 1.4 8.0 0.0 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.16 GAO83852.1 - 3.6e-52 177.0 0.0 4.3e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.8 GAO83853.1 - 3.8e-49 166.2 0.0 5.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAO83853.1 - 1.4e-08 35.1 0.0 5.4e-08 33.2 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAO83853.1 - 0.00076 19.5 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 GAO83853.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 GAO83853.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aa_trans PF01490.13 GAO83855.1 - 1.9e-55 188.0 18.4 2.2e-55 187.8 12.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAM2 PF07145.10 GAO83856.1 - 2.7e-05 23.3 0.6 9.4e-05 21.6 0.4 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Rad52_Rad22 PF04098.10 GAO83857.1 - 1.8e-63 212.9 0.2 2.4e-63 212.4 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.26 GAO83858.1 - 5.6e-05 22.8 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 GAO83858.1 - 0.00056 19.9 0.0 0.0019 18.2 0.0 2.0 1 0 0 1 1 1 1 UBX domain zf-C2H2_2 PF12756.2 GAO83858.1 - 0.051 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 GAO83858.1 - 0.055 13.8 0.2 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rtf2 PF04641.7 GAO83858.1 - 0.36 9.9 15.6 0.54 9.4 10.8 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger SOBP PF15279.1 GAO83858.1 - 0.99 9.7 9.5 1.2 9.4 6.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 GAO83858.1 - 1.7 6.2 9.8 1.9 6.1 6.8 1.2 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.5 GAO83858.1 - 1.9 6.8 5.5 2.4 6.4 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PLRV_ORF5 PF01690.12 GAO83858.1 - 5.4 6.0 14.5 6.9 5.6 10.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Motile_Sperm PF00635.21 GAO83859.1 - 1.9e-24 85.3 1.6 9.4e-24 83.1 0.2 2.4 2 1 1 3 3 3 1 MSP (Major sperm protein) domain Phage_GP20 PF06810.6 GAO83859.1 - 0.028 13.8 1.2 0.057 12.8 0.9 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 FixG_C PF11614.3 GAO83859.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Golgin_A5 PF09787.4 GAO83859.1 - 0.066 11.7 5.0 0.088 11.3 3.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2077 PF09850.4 GAO83859.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4588 PF15251.1 GAO83859.1 - 0.19 11.7 7.4 0.26 11.2 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) FA_desaturase PF00487.19 GAO83860.1 - 1.7e-25 89.9 17.6 6.8e-25 87.9 12.2 1.9 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 GAO83860.1 - 2.5e-20 71.3 0.1 2.5e-20 71.3 0.1 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.19 GAO83861.1 - 4.5e-47 160.2 0.0 5.9e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 GAO83861.1 - 0.039 12.5 0.0 0.06 11.9 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase DnaJ PF00226.26 GAO83862.1 - 1.9e-22 78.7 0.2 2.9e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 GAO83863.1 - 2.9e-68 230.1 0.1 4.3e-68 229.5 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 GAO83863.1 - 0.077 12.6 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Asn_synthase PF00733.16 GAO83864.1 - 3.2e-70 236.5 0.1 4.3e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAO83864.1 - 5e-36 123.1 0.0 8.7e-36 122.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAO83864.1 - 2.5e-25 88.9 0.0 7.5e-25 87.4 0.0 1.8 2 1 1 3 3 3 1 Glutamine amidotransferase domain DUF3700 PF12481.3 GAO83864.1 - 2.4e-09 36.7 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 GAO83864.1 - 0.0011 17.7 0.0 0.092 11.4 0.0 2.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 GAO83864.1 - 0.0029 16.5 0.0 0.0046 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD synthase p450 PF00067.17 GAO83865.1 - 3.4e-71 240.1 0.0 3.9e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med4 PF10018.4 GAO83866.1 - 0.00079 18.8 4.5 0.00079 18.8 3.1 1.7 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Rootletin PF15035.1 GAO83866.1 - 0.0019 18.2 6.2 0.0029 17.5 4.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Herpes_UL6 PF01763.11 GAO83866.1 - 0.0026 16.0 1.1 0.0034 15.6 0.7 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF972 PF06156.8 GAO83866.1 - 0.013 15.8 2.0 0.013 15.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAO83866.1 - 0.19 11.2 6.0 0.48 9.9 4.1 1.7 1 0 0 1 1 1 0 Septum formation initiator NTR2 PF15458.1 GAO83866.1 - 0.35 10.0 10.6 0.64 9.2 7.4 1.4 1 0 0 1 1 1 0 Nineteen complex-related protein 2 I_LWEQ PF01608.12 GAO83866.1 - 0.98 9.3 5.7 1.5 8.7 4.0 1.2 1 0 0 1 1 1 0 I/LWEQ domain Anp1 PF03452.9 GAO83867.1 - 1.1e-108 362.4 0.0 1.5e-108 362.0 0.0 1.2 1 0 0 1 1 1 1 Anp1 YCII PF03795.9 GAO83868.1 - 9.6e-12 44.9 0.0 1.1e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain AMP-binding PF00501.23 GAO83869.1 - 7.2e-86 288.1 0.0 1.1e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO83869.1 - 1.5e-16 61.0 0.2 6e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAO83869.1 - 0.002 16.7 0.0 0.013 14.0 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.18 GAO83870.1 - 4.5e-10 39.1 1.1 9e-10 38.1 0.8 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 GAO83870.1 - 2.8e-06 27.0 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO83870.1 - 8.5e-06 25.3 0.1 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 GAO83870.1 - 0.0083 15.9 0.4 0.032 14.0 0.3 2.0 1 1 0 1 1 1 1 DExH-box splicing factor binding site RRM_6 PF14259.1 GAO83870.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 GAO83871.1 - 9.4e-43 144.9 0.0 2.8e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO83871.1 - 0.0011 18.7 0.1 0.28 10.9 0.0 2.3 1 1 1 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 GAO83871.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 RWD domain Ecm33 PF12454.3 GAO83872.1 - 6.4e-18 64.3 1.3 6.4e-18 64.3 0.9 2.5 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 GAO83872.1 - 4.2e-07 29.7 1.9 0.0072 16.0 0.3 2.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) Recep_L_domain PF01030.19 GAO83872.1 - 5.2e-05 23.1 6.2 1.4 8.9 0.0 4.4 1 1 4 5 5 5 2 Receptor L domain HhH-GPD PF00730.20 GAO83873.1 - 1.8e-15 57.1 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 GAO83873.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) UCR_14kD PF02271.11 GAO83874.1 - 3e-47 158.7 0.1 3.4e-47 158.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4211 PF13926.1 GAO83874.1 - 0.064 12.6 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF4541 PF15074.1 GAO83874.1 - 0.11 13.0 0.1 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4541) Mito_carr PF00153.22 GAO83875.1 - 1.5e-66 220.1 0.0 1.6e-21 75.7 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein NifU_N PF01592.11 GAO83876.1 - 2.5e-49 166.4 0.0 3.7e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Pkinase PF00069.20 GAO83877.1 - 6.7e-71 238.4 0.0 8.9e-70 234.7 0.0 2.8 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83877.1 - 1.3e-50 171.9 0.0 5.9e-50 169.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase ABC1 PF03109.11 GAO83877.1 - 3e-33 114.3 0.0 4.8e-31 107.2 0.0 2.8 2 0 0 2 2 2 1 ABC1 family Kinase-like PF14531.1 GAO83877.1 - 0.0039 16.2 0.0 0.017 14.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAO83877.1 - 0.0043 16.4 0.0 0.055 12.8 0.0 2.4 2 0 0 2 2 2 1 RIO1 family HEAT PF02985.17 GAO83877.1 - 0.22 11.6 0.9 32 4.9 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat FBP PF07299.6 GAO83877.1 - 0.5 9.6 0.6 33 3.7 0.2 2.5 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Mur_ligase_M PF08245.7 GAO83878.1 - 5.2e-06 26.6 0.2 1.3e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 GAO83878.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain AAA_17 PF13207.1 GAO83880.1 - 0.00021 22.1 0.3 0.0012 19.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO83880.1 - 0.00033 20.9 0.0 0.0083 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAO83880.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.13 GAO83880.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 GAO83880.1 - 0.02 14.9 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAO83880.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 GAO83880.1 - 0.073 12.9 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAO83880.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 GAO83880.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Macoilin PF09726.4 GAO83881.1 - 4.1 5.5 8.8 4.6 5.4 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Ribonuc_red_lgC PF02867.10 GAO83882.1 - 2.9e-217 722.5 0.0 1.4e-216 720.2 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAO83882.1 - 6.8e-24 83.4 0.0 1.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAO83882.1 - 8.2e-17 61.4 0.1 2.4e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain DPBB_1 PF03330.13 GAO83883.1 - 0.00029 20.7 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAO83883.1 - 0.015 14.9 0.3 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Barwin family TFIIA PF03153.8 GAO83883.1 - 9.3 6.0 7.2 11 5.7 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.23 GAO83884.1 - 1.5e-16 60.4 0.6 2.1e-16 59.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO83884.1 - 7e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 GAO83885.1 - 1.4e-16 60.1 27.2 1.4e-16 60.1 18.9 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily Glyco_transf_6 PF03414.8 GAO83885.1 - 0.094 11.1 0.2 1.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 6 ELFV_dehydrog PF00208.16 GAO83886.1 - 3.1e-83 279.1 3.2 3.9e-83 278.7 2.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAO83886.1 - 5.8e-48 161.7 0.0 1.1e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.5 GAO83888.1 - 0 1100.0 0.0 0 1099.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 FNIP_C PF14638.1 GAO83888.1 - 0.088 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus RasGEF PF00617.14 GAO83889.1 - 1.1e-55 188.2 0.3 2.2e-55 187.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAO83889.1 - 8.2e-18 64.4 0.0 2.4e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 GAO83889.1 - 1.1e-06 28.0 0.0 2.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO83889.1 - 1.3e-05 24.4 0.1 4.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 SH3 domain DUF974 PF06159.8 GAO83890.1 - 7.4e-81 271.2 0.0 8.9e-81 271.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-RING_2 PF13639.1 GAO83891.1 - 2.4e-07 30.4 5.1 2.4e-07 30.4 3.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 GAO83891.1 - 0.00072 19.3 4.0 0.00072 19.3 2.8 2.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 GAO83891.1 - 0.003 17.2 1.2 0.003 17.2 0.8 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 GAO83891.1 - 0.0056 16.7 3.9 0.0056 16.7 2.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAO83891.1 - 0.0063 16.2 5.2 0.0063 16.2 3.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 GAO83891.1 - 0.0071 16.2 7.7 0.041 13.8 3.5 2.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_4 PF14570.1 GAO83891.1 - 0.015 14.8 6.9 0.031 13.8 4.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 GAO83891.1 - 0.086 12.5 7.2 0.18 11.5 5.0 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 GAO83891.1 - 0.27 11.0 6.9 0.81 9.4 1.6 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 GAO83891.1 - 0.92 9.5 10.5 0.14 12.2 4.2 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) SCRL PF06876.7 GAO83891.1 - 2.2 8.3 6.8 1 9.3 1.5 2.5 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein RINGv PF12906.2 GAO83891.1 - 4.7 7.3 11.9 0.94 9.5 5.6 1.9 2 0 0 2 2 2 0 RING-variant domain CENP-N PF05238.8 GAO83892.1 - 1.2e-142 475.6 0.0 1.4e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 GAO83893.1 - 4.5e-13 48.8 11.4 9.5e-13 47.7 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAO83893.1 - 0.00023 21.0 12.3 0.00047 20.0 8.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2984 PF11203.3 GAO83893.1 - 0.25 11.4 5.8 0.73 9.9 3.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) Hamartin PF04388.7 GAO83893.1 - 0.27 9.8 12.7 0.38 9.3 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein CAF-1_p150 PF11600.3 GAO83893.1 - 2.2 7.5 21.2 8.9 5.6 14.7 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal IncA PF04156.9 GAO83893.1 - 2.5 7.6 6.2 4.4 6.8 4.3 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 GAO83893.1 - 4.2 7.7 6.3 6.8 7.0 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2834 PF11196.3 GAO83894.1 - 0.0005 20.1 16.1 0.44 10.7 1.5 3.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) NAD_binding_8 PF13450.1 GAO83896.1 - 1.3e-12 47.5 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAO83896.1 - 1.6e-06 27.4 0.9 0.002 17.3 0.3 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAO83896.1 - 0.0035 17.1 0.5 0.17 11.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.19 GAO83896.1 - 0.0035 17.6 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DAO PF01266.19 GAO83896.1 - 0.004 16.1 0.0 0.0089 14.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO83896.1 - 0.0081 16.0 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO83896.1 - 0.013 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 GAO83896.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 GAO83896.1 - 0.02 13.5 0.0 0.036 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 GAO83896.1 - 0.048 12.7 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 GAO83896.1 - 0.097 11.5 1.0 1.2 7.9 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.18 GAO83896.1 - 0.1 12.2 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rubella_E2 PF05749.6 GAO83897.1 - 0.16 11.1 5.8 0.29 10.3 4.0 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 HATPase_c_3 PF13589.1 GAO83898.1 - 5e-20 71.5 0.0 1.5e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 GAO83898.1 - 1.6e-09 37.5 0.0 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 GAO83898.1 - 1.6e-07 31.0 0.1 4.8e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DENN PF02141.16 GAO83899.1 - 3.5e-57 193.1 0.0 5.9e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 GAO83899.1 - 8.7e-21 73.7 0.4 2.6e-20 72.2 0.3 1.9 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 GAO83899.1 - 3.8e-17 62.0 0.0 8.5e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 uDENN domain SPA PF08616.5 GAO83899.1 - 0.056 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Leader_CPA1 PF08252.6 GAO83899.1 - 0.11 11.8 0.3 0.26 10.5 0.2 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DHquinase_I PF01487.10 GAO83900.1 - 1.9e-55 187.9 0.0 2.5e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 GAO83901.1 - 3.9e-20 71.8 0.0 7.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO83901.1 - 5.1e-06 26.2 16.8 8.7e-06 25.5 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 GAO83901.1 - 0.63 8.7 2.8 1.1 7.9 1.9 1.3 1 0 0 1 1 1 0 Clusterin SelP_N PF04592.9 GAO83901.1 - 1.7 7.9 15.9 3.5 6.9 11.0 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3632 PF12311.3 GAO83902.1 - 4.3e-23 82.0 0.0 6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DDRGK PF09756.4 GAO83902.1 - 0.083 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 DDRGK domain BRO1 PF03097.13 GAO83903.1 - 2.4e-119 398.4 0.1 4.9e-119 397.4 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAO83903.1 - 6.5e-84 281.3 11.2 6.5e-84 281.3 7.7 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 GAO83904.1 - 7.6e-43 144.1 2.9 1.5e-15 56.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_C PF02803.13 GAO83905.1 - 1.2e-11 44.1 0.7 8.9e-11 41.2 0.5 2.3 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 GAO83905.1 - 5.9e-08 32.2 0.1 3e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 GAO83905.1 - 8.8e-06 24.8 2.3 1e-05 24.6 0.1 2.3 3 1 0 3 3 3 1 Thiolase, N-terminal domain SpoVAD PF07451.6 GAO83905.1 - 0.015 13.7 0.1 0.029 12.8 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 GAO83905.1 - 0.023 14.1 0.1 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3208 PF11482.3 GAO83905.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SMN PF06003.7 GAO83907.1 - 0.00025 20.2 13.8 0.12 11.4 0.2 3.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Lin-8 PF03353.10 GAO83907.1 - 1.3 8.2 4.7 1.4 8.0 3.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RRM_1 PF00076.17 GAO83908.1 - 4e-14 51.9 0.0 7.7e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO83908.1 - 5.1e-10 39.1 0.0 9.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO83908.1 - 8.3e-09 35.1 0.1 1.7e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO83908.1 - 0.036 13.8 0.0 0.094 12.5 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CHD5 PF04420.9 GAO83909.1 - 4e-64 215.1 3.7 5.4e-64 214.7 2.6 1.2 1 0 0 1 1 1 1 CHD5-like protein DUF3293 PF11697.3 GAO83909.1 - 0.12 12.4 0.3 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) PPTA PF01239.17 GAO83910.1 - 0.0092 15.3 5.1 0.56 9.6 0.8 2.9 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Hamartin PF04388.7 GAO83912.1 - 0.053 12.1 0.0 0.068 11.8 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein TRAM_LAG1_CLN8 PF03798.11 GAO83913.1 - 1.9e-39 135.2 26.4 1.9e-39 135.2 18.3 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAO83913.1 - 4.2e-20 71.0 0.2 1.1e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein Fungal_trans_2 PF11951.3 GAO83914.1 - 2.8e-13 49.2 0.1 4.2e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rad10 PF03834.9 GAO83915.1 - 9.5e-32 108.5 0.0 1.6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 GAO83915.1 - 0.00011 22.2 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 GAO83915.1 - 0.00025 20.5 0.0 0.00066 19.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 GAO83915.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 GAO83916.1 - 1.4e-61 204.0 0.0 1.5e-19 69.3 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO83916.1 - 2.3e-42 142.8 0.0 1.1e-12 47.7 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO83916.1 - 5.7e-23 80.5 0.0 1.2e-07 31.4 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 GAO83916.1 - 0.074 10.9 38.5 0.0028 15.6 15.2 2.2 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 GAO83916.1 - 0.58 8.1 36.9 0.01 13.9 9.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Cyt-b5 PF00173.23 GAO83917.1 - 2.8e-09 36.6 0.0 3.4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 GAO83918.1 - 1.2e-102 343.7 39.5 1.9e-96 323.3 18.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 GAO83918.1 - 3e-20 72.1 29.9 3e-20 72.1 20.7 1.7 2 0 0 2 2 2 1 Amino acid permease DUF1772 PF08592.6 GAO83918.1 - 0.0093 15.7 1.2 0.0093 15.7 0.8 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF1772) DUF3487 PF11990.3 GAO83918.1 - 0.062 12.6 0.1 0.062 12.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) DUF1289 PF06945.8 GAO83919.1 - 0.12 11.8 0.2 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Cupin_8 PF13621.1 GAO83920.1 - 2.8e-29 102.3 0.0 3.6e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 GAO83920.1 - 0.0081 15.6 0.1 0.025 14.0 0.1 1.9 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.17 GAO83920.1 - 0.032 14.4 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_4 PF08007.7 GAO83920.1 - 0.044 13.0 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein DUF3701 PF12482.3 GAO83920.1 - 0.17 11.6 1.2 2.2 8.0 1.3 2.1 2 0 0 2 2 2 0 Phage integrase protein Pyr_redox_3 PF13738.1 GAO83921.1 - 3e-22 79.6 0.0 6.6e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAO83921.1 - 5.6e-19 68.0 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.14 GAO83921.1 - 9.1e-10 37.3 0.8 1.6e-08 33.2 0.6 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAO83921.1 - 1.2e-08 34.8 0.0 7.7e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAO83921.1 - 1e-07 31.2 0.1 6.6e-07 28.5 0.0 2.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAO83921.1 - 0.0028 16.6 0.0 1.4 7.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO83921.1 - 0.072 12.9 0.0 3.7 7.3 0.0 2.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO83921.1 - 0.088 13.2 0.0 15 6.0 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO83921.1 - 0.2 10.7 0.0 0.6 9.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family CK_II_beta PF01214.13 GAO83922.1 - 7.9e-79 263.4 0.0 2.3e-78 261.9 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 GAO83922.1 - 0.0016 19.0 8.3 0.0016 19.0 5.8 1.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 GAO83922.1 - 0.18 11.3 7.9 0.28 10.6 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin LZ_Tnp_IS66 PF13007.2 GAO83922.1 - 0.49 11.0 7.5 2.1 9.0 0.6 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Myc_N PF01056.13 GAO83922.1 - 2.4 7.2 5.3 3.8 6.5 3.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region bZIP_1 PF00170.16 GAO83923.1 - 4.1e-05 23.4 6.8 7.5e-05 22.6 4.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO83923.1 - 0.0031 17.3 8.3 0.0031 17.3 5.8 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAO83923.1 - 0.075 13.3 5.3 0.16 12.3 3.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Aminotran_4 PF01063.14 GAO83924.1 - 1.3e-28 100.0 0.0 2.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Peptidase_M49 PF03571.10 GAO83925.1 - 4.6e-232 770.9 0.0 7.1e-232 770.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M49 Pkinase PF00069.20 GAO83925.1 - 2.8e-18 66.0 0.0 7.6e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83925.1 - 3.1e-10 39.5 0.0 9.9e-10 37.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase SNF5 PF04855.7 GAO83927.1 - 1.5e-91 306.2 0.0 2e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF4597 PF15366.1 GAO83928.1 - 0.025 14.1 0.4 0.089 12.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) WD40 PF00400.27 GAO83930.1 - 6.3e-43 143.1 24.3 1.1e-12 47.2 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 GAO83930.1 - 2.3e-06 27.4 16.5 0.0099 15.6 1.6 3.8 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.19 GAO83932.1 - 1.7e-105 353.1 17.8 2.4e-105 352.7 12.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO83932.1 - 2.4e-27 95.5 24.5 2.4e-27 95.5 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 GAO83932.1 - 9.7e-06 24.3 8.1 0.00032 19.3 1.7 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.8 GAO83932.1 - 0.00027 19.2 6.1 0.00027 19.2 4.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAO83932.1 - 0.0051 16.5 1.3 0.075 12.8 0.0 2.8 2 0 0 2 2 2 1 MFS_1 like family PspC PF04024.7 GAO83932.1 - 0.028 13.8 0.4 0.028 13.8 0.3 2.6 2 0 0 2 2 2 0 PspC domain ABC_tran PF00005.22 GAO83933.1 - 2.4e-49 167.1 0.4 5.7e-24 84.9 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 GAO83933.1 - 3.3e-21 74.9 5.7 3.3e-21 74.9 3.9 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 GAO83933.1 - 4.3e-15 56.4 3.6 0.0011 18.9 0.2 4.7 4 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAO83933.1 - 2.1e-10 40.2 0.7 0.035 13.3 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAO83933.1 - 2.7e-08 34.6 0.7 0.0098 16.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 GAO83933.1 - 1.2e-06 28.5 0.0 0.013 15.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 GAO83933.1 - 2.3e-06 26.9 3.3 0.19 10.7 0.0 4.7 4 2 1 5 5 5 2 AAA ATPase domain AAA_16 PF13191.1 GAO83933.1 - 2.4e-06 27.6 0.3 0.0066 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAO83933.1 - 3.4e-06 26.3 0.1 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAO83933.1 - 5.3e-06 25.8 0.1 0.07 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAO83933.1 - 8.8e-06 26.2 0.0 0.041 14.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 GAO83933.1 - 1.7e-05 25.0 0.2 0.22 11.6 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO83933.1 - 2.9e-05 24.3 4.3 0.18 12.0 0.0 3.6 5 0 0 5 5 2 2 AAA domain MobB PF03205.9 GAO83933.1 - 0.00016 21.3 0.1 0.64 9.7 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAO83933.1 - 0.00022 21.0 7.7 0.21 11.4 0.0 3.6 3 1 0 4 4 3 2 Dynamin family AAA_23 PF13476.1 GAO83933.1 - 0.00024 21.5 16.6 0.019 15.3 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 GAO83933.1 - 0.00037 20.3 0.1 0.78 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 GAO83933.1 - 0.00045 19.8 0.0 0.03 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAO83933.1 - 0.00063 19.7 2.9 0.42 10.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 GAO83933.1 - 0.001 17.8 0.2 1.1 7.9 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 GAO83933.1 - 0.0013 18.9 0.1 1.2 9.3 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAO83933.1 - 0.0013 18.4 1.3 0.6 9.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 GAO83933.1 - 0.0036 17.2 0.1 5.9 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAO83933.1 - 0.0073 16.4 0.0 4.9 7.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 GAO83933.1 - 0.012 15.4 0.0 8.9 6.3 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAO83933.1 - 0.013 14.9 3.0 3.4 7.0 0.1 3.8 4 1 1 5 5 5 0 AAA-like domain NTPase_1 PF03266.10 GAO83933.1 - 0.016 14.9 0.1 2.8 7.6 0.1 2.7 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 GAO83933.1 - 0.017 14.2 2.1 0.66 9.0 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 GAO83933.1 - 0.017 14.5 0.4 2.9 7.3 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 GAO83933.1 - 0.017 14.6 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 GAO83933.1 - 0.018 14.7 0.1 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 GAO83933.1 - 0.021 13.6 0.1 4.1 6.1 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 GAO83933.1 - 0.022 14.3 0.0 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAO83933.1 - 0.03 13.8 0.1 9.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 GAO83933.1 - 0.051 12.9 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAO83933.1 - 0.056 12.8 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MFS_1 PF07690.11 GAO83935.1 - 3.4e-11 42.4 17.2 1.1e-09 37.5 4.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SKG6 PF08693.5 GAO83936.1 - 7.3e-10 38.0 10.2 5.3e-07 28.8 2.5 2.6 2 0 0 2 2 2 2 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 GAO83936.1 - 0.004 16.8 5.4 0.14 11.8 1.9 2.8 2 1 1 3 3 3 1 Rifin/stevor family EphA2_TM PF14575.1 GAO83936.1 - 0.0075 16.6 0.0 7.8 6.9 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DcuC PF03606.10 GAO83936.1 - 0.042 12.0 0.0 0.16 10.1 0.0 1.7 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier DUF912 PF06024.7 GAO83936.1 - 0.12 12.4 0.1 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 GAO83936.1 - 0.16 11.6 32.5 0.65 9.6 0.0 3.9 2 1 0 2 2 2 0 TMEM154 protein family DUF2681 PF10883.3 GAO83936.1 - 0.34 11.1 0.5 1.8 8.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_M56 PF05569.6 GAO83936.1 - 1.6 7.6 1.4 36 3.1 0.0 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 Ank_2 PF12796.2 GAO83937.1 - 2.4e-44 149.5 6.9 1.5e-13 50.8 0.3 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO83937.1 - 1.4e-26 92.3 5.8 6.7e-10 39.2 0.0 5.5 5 2 1 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.14 GAO83937.1 - 1.7e-25 90.3 6.9 3.7e-16 59.7 0.9 2.3 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 GAO83937.1 - 4.3e-24 83.0 7.1 8.8e-05 22.1 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 GAO83937.1 - 5.3e-19 67.8 7.9 2.4e-06 27.5 0.0 6.2 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83937.1 - 3.3e-18 63.9 8.4 0.00019 21.3 0.0 9.3 9 0 0 9 9 9 3 Ankyrin repeat GDPD PF03009.12 GAO83937.1 - 6.6e-11 42.2 0.0 1.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DRAT PF07357.6 GAO83937.1 - 0.037 13.2 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF1279 PF06916.8 GAO83938.1 - 1.8e-30 105.0 0.0 2.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 GAO83939.1 - 1.1e-39 136.4 6.7 2.5e-38 131.9 4.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 GAO83940.1 - 2.7e-42 142.9 0.1 6.5e-42 141.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 JmjC PF02373.17 GAO83940.1 - 2.4e-09 37.4 3.2 4.7e-09 36.5 0.4 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 GAO83940.1 - 0.007 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 GAO83941.1 - 8.8e-36 123.4 20.0 1.2e-35 122.9 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CTP_transf_2 PF01467.21 GAO83942.1 - 9e-19 68.0 0.0 1.3e-15 57.7 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase PRELI PF04707.9 GAO83944.1 - 1e-43 148.6 0.2 1.2e-43 148.4 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 GAO83944.1 - 0.076 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AhpC-TSA PF00578.16 GAO83945.1 - 3e-21 75.3 0.0 6.8e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAO83945.1 - 1.7e-14 53.5 0.0 3.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin DUF1761 PF08570.5 GAO83946.1 - 1.7e-23 82.9 2.7 2e-23 82.7 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 GAO83946.1 - 0.71 9.9 0.1 0.71 9.9 0.1 2.6 2 1 1 3 3 3 0 Na+/H+ antiporter subunit Mpp10 PF04006.7 GAO83947.1 - 3.8e-84 283.1 32.5 3.3e-82 276.7 22.5 2.2 1 1 0 1 1 1 1 Mpp10 protein adh_short PF00106.20 GAO83948.1 - 4.2e-30 104.8 0.0 5.9e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO83948.1 - 2.3e-23 83.2 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO83948.1 - 3.1e-12 46.5 0.0 4.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO83948.1 - 0.01 15.6 0.2 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO83948.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_q6 PF01058.17 GAO83949.1 - 3.7e-22 78.3 0.0 5.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Acyl_transf_1 PF00698.16 GAO83950.1 - 8.1e-11 41.8 0.0 1.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.9 GAO83951.1 - 6.7e-140 467.3 13.7 8.7e-140 467.0 9.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAO83951.1 - 2.2e-76 257.3 0.0 3.1e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Amidase02_C PF12123.3 GAO83951.1 - 0.035 13.7 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase IF-2B PF01008.12 GAO83952.1 - 1.3e-75 254.0 2.7 1.6e-75 253.6 1.9 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family tRNA-synt_1b PF00579.20 GAO83953.1 - 3.1e-71 239.8 0.0 5.7e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Asp PF00026.18 GAO83953.1 - 7.8e-68 229.0 2.0 1e-67 228.6 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO83953.1 - 2.5e-07 30.7 2.6 3.8e-07 30.2 1.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAO83953.1 - 0.00033 21.0 3.7 0.21 12.0 0.2 4.2 4 1 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 GAO83953.1 - 0.00069 19.1 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Ribosomal_S10 PF00338.17 GAO83954.1 - 4.9e-25 87.2 0.0 1.8e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.15 GAO83955.1 - 5.1e-38 130.3 0.1 6.8e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 GAO83956.1 - 2.5e-30 104.4 2.0 3.4e-30 103.9 0.1 2.1 2 1 0 3 3 3 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 GAO83957.1 - 4.6e-19 68.2 0.6 8.4e-19 67.3 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO83957.1 - 2.2e-12 46.8 0.1 4.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 GAO83957.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 GAO83958.1 - 1.3e-118 395.8 0.4 1.3e-118 395.8 0.3 2.6 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 GAO83958.1 - 0.00014 21.6 6.5 0.00056 19.6 1.3 3.1 2 1 1 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.6 GAO83958.1 - 0.001 18.9 4.2 0.001 18.9 2.9 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 GAO83958.1 - 0.0051 16.4 2.8 0.0051 16.4 1.9 2.9 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 GAO83958.1 - 0.013 15.5 6.3 0.041 13.8 3.1 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2450 PF10475.4 GAO83958.1 - 0.057 12.3 9.5 0.016 14.1 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF4206 PF13901.1 GAO83958.1 - 0.07 12.6 3.4 0.3 10.5 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) FUSC PF04632.7 GAO83958.1 - 0.46 8.8 5.9 0.85 7.9 4.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phosphodiest PF01663.17 GAO83959.1 - 1.2e-12 47.8 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAO83959.1 - 7.8e-05 21.9 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 GAO83959.1 - 0.0015 17.0 0.1 0.0022 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 GAO83959.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF202 PF02656.10 GAO83959.1 - 2.2 8.5 4.9 23 5.2 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2069 PF09842.4 GAO83959.1 - 7.3 6.5 9.1 1.7 8.6 0.8 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2069) PINIT PF14324.1 GAO83960.1 - 1.7e-35 122.2 0.2 3.5e-35 121.1 0.2 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 GAO83960.1 - 1.7e-21 75.4 6.4 3.3e-21 74.5 4.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 GAO83960.1 - 8.4e-08 31.5 0.1 2.3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 GAO83960.1 - 2.1e-05 23.9 2.6 4.6e-05 22.8 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ldh_1_N PF00056.18 GAO83961.1 - 7e-43 145.8 0.1 7.2e-29 100.4 0.0 2.4 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAO83961.1 - 1.2e-38 132.5 0.0 1.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAO83961.1 - 0.1 11.2 0.0 0.82 8.3 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.12 GAO83962.1 - 9.4e-40 135.6 2.6 2.3e-39 134.4 1.8 1.6 1 1 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 GAO83963.1 - 1.9e-50 169.9 0.0 2.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.17 GAO83964.1 - 2.1e-36 123.3 0.0 8.3e-18 63.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO83964.1 - 5.1e-20 71.2 0.0 4.1e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO83964.1 - 3.1e-16 58.9 0.0 6.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAO83964.1 - 0.007 15.8 0.2 0.49 9.9 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 GAO83964.1 - 0.027 14.2 0.2 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Mito_carr PF00153.22 GAO83965.1 - 1.4e-68 226.6 1.2 1.3e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 GAO83966.1 - 6.3e-20 70.2 21.5 0.0001 22.4 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO83966.1 - 1.5e-15 56.6 23.6 6.7e-08 32.4 0.5 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO83966.1 - 1.3e-14 53.3 19.2 0.0015 18.7 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 GAO83966.1 - 0.0049 17.0 12.0 0.056 13.6 0.7 3.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO83966.1 - 0.08 13.1 0.5 0.08 13.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 GAO83966.1 - 0.27 10.9 4.6 4.1 7.1 0.1 3.4 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 GAO83966.1 - 0.86 9.5 15.0 1.5 8.8 0.8 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.6 GAO83966.1 - 1.5 8.5 7.9 6.2 6.6 0.1 3.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger WD40 PF00400.27 GAO83967.1 - 1.2e-74 243.6 12.0 8.4e-13 47.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 GAO83967.1 - 2.5e-26 91.6 10.9 3.7e-26 91.1 7.6 1.2 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 GAO83967.1 - 1.4e-05 23.5 0.3 0.00019 19.8 0.1 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 GAO83967.1 - 0.00028 19.1 0.1 0.12 10.4 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 GAO83967.1 - 0.015 14.4 0.1 4.9 6.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 GAO83967.1 - 0.077 12.4 0.7 4 6.8 0.1 2.7 2 1 1 3 3 3 0 PQQ-like domain FA_hydroxylase PF04116.8 GAO83968.1 - 4.1e-13 49.7 17.2 4.1e-13 49.7 11.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M56 PF05569.6 GAO83968.1 - 0.023 13.6 0.1 0.037 12.9 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 MIF4G_like PF09088.6 GAO83969.1 - 9e-85 282.9 0.0 1.5e-84 282.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 GAO83969.1 - 1.2e-61 208.1 0.0 3.4e-61 206.6 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 GAO83969.1 - 8e-07 28.6 0.0 4.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain Pkinase PF00069.20 GAO83970.1 - 1.2e-64 217.9 0.0 1.4e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO83970.1 - 1.5e-25 89.7 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO83970.1 - 5.6e-07 28.7 0.0 1.9e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAO83970.1 - 0.0011 18.7 0.3 0.013 15.2 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO83970.1 - 0.054 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 GAO83970.1 - 0.057 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Porin_3 PF01459.17 GAO83971.1 - 6.5e-84 281.4 0.0 7.5e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 GAO83971.1 - 0.0022 17.3 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.13 GAO83972.1 - 1.9e-38 131.8 0.9 3.2e-38 131.0 0.7 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAO83972.1 - 1.3e-22 80.5 1.2 1.9e-22 80.0 0.8 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 GAO83973.1 - 2.1e-62 204.8 27.2 6.9e-08 32.0 0.4 12.7 13 0 0 13 13 13 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAO83973.1 - 0.00081 19.1 0.0 1.8 8.3 0.0 4.7 6 0 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region ABC_tran PF00005.22 GAO83974.1 - 4.8e-17 62.5 0.1 4.6e-16 59.3 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAO83974.1 - 5.8e-11 42.9 0.1 9e-05 22.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAO83974.1 - 7.9e-05 21.8 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAO83974.1 - 0.00036 20.0 0.2 0.00075 18.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 GAO83974.1 - 0.001 18.3 0.0 0.47 9.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 GAO83974.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 GAO83974.1 - 0.0023 15.3 0.6 0.0032 14.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 GAO83974.1 - 0.0046 16.3 0.1 0.0086 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAO83974.1 - 0.0051 16.6 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAO83974.1 - 0.0069 16.5 0.0 0.042 14.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAO83974.1 - 0.009 16.3 0.2 0.017 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAO83974.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAO83974.1 - 0.012 16.3 0.4 0.028 15.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAO83974.1 - 0.013 15.6 0.4 0.094 12.8 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAO83974.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAO83974.1 - 0.021 14.2 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 GAO83974.1 - 0.021 14.7 1.3 0.056 13.4 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 GAO83974.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Arf PF00025.16 GAO83974.1 - 0.099 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 GAO83974.1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 GAO83974.1 - 0.12 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 GAO83974.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_33 PF13671.1 GAO83974.1 - 0.13 12.1 0.1 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 GAO83974.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAO83974.1 - 0.15 11.7 0.3 0.89 9.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 GAO83974.1 - 0.2 11.0 0.2 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IPPT PF01715.12 GAO83975.1 - 6.4e-55 185.9 0.1 1.7e-54 184.5 0.0 1.7 1 1 0 1 1 1 1 IPP transferase zf-met PF12874.2 GAO83975.1 - 2.4e-06 27.5 0.1 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO83975.1 - 3.6e-06 26.9 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 GAO83975.1 - 2.7e-05 24.9 0.2 0.0001 23.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO83975.1 - 4.2e-05 23.4 0.5 0.088 12.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain IPT PF01745.11 GAO83975.1 - 0.0023 17.1 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.1 GAO83975.1 - 0.0053 17.0 0.2 0.082 13.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO83975.1 - 0.0056 16.0 0.0 0.054 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO83975.1 - 0.027 14.5 0.0 0.63 10.1 0.0 2.7 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAO83975.1 - 0.031 14.2 1.1 0.59 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.2 GAO83975.1 - 0.043 13.9 0.1 0.08 13.0 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_16 PF13191.1 GAO83975.1 - 0.061 13.3 0.2 0.35 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain RAI1 PF08652.6 GAO83976.1 - 6.6e-30 102.6 0.1 1.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 GAO83977.1 - 3.1e-42 144.9 0.0 3.6e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Rep_fac_C PF08542.6 GAO83979.1 - 1.2e-20 73.2 0.0 2.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAO83979.1 - 5.4e-13 48.9 0.0 5.9e-11 42.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAO83979.1 - 1.4e-11 44.7 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAO83979.1 - 9.3e-08 32.0 0.0 4.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 GAO83979.1 - 6.8e-07 28.3 0.0 0.024 13.3 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 GAO83979.1 - 4.3e-06 26.4 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 GAO83979.1 - 1.5e-05 25.1 0.0 0.00022 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO83979.1 - 1.8e-05 24.8 0.0 0.0034 17.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAO83979.1 - 3.3e-05 23.4 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO83979.1 - 3.4e-05 23.0 0.0 7.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 GAO83979.1 - 0.00091 18.7 0.0 0.05 13.0 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 GAO83979.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 GAO83979.1 - 0.0024 17.5 0.0 0.0036 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAO83979.1 - 0.0028 16.8 0.1 0.029 13.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 GAO83979.1 - 0.0031 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ArgK PF03308.11 GAO83979.1 - 0.0043 15.8 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 GAO83979.1 - 0.0048 16.6 0.1 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 GAO83979.1 - 0.01 15.2 0.1 0.19 11.1 0.0 2.9 2 1 1 4 4 4 0 AAA domain KTI12 PF08433.5 GAO83979.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.24 GAO83979.1 - 0.025 14.0 0.1 2.1 7.8 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 GAO83979.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAO83979.1 - 0.037 14.3 0.0 0.064 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 GAO83979.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO83979.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Polysacc_deac_1 PF01522.16 GAO83980.1 - 1.7e-24 85.8 0.0 3.3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Parvo_coat PF00740.13 GAO83980.1 - 0.011 14.7 0.5 0.014 14.3 0.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2334 PF10096.4 GAO83980.1 - 0.023 14.0 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.16 GAO83981.1 - 2e-101 340.0 0.0 2.3e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 GAO83982.1 - 2.9e-10 39.4 0.2 4.6e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 GAO83983.1 - 2.2e-40 138.9 0.0 5.5e-40 137.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAO83983.1 - 9.5e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAO83983.1 - 0.023 14.4 2.4 0.41 10.6 0.2 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat AA_permease_2 PF13520.1 GAO83984.1 - 1.9e-61 207.9 49.0 1.1e-60 205.4 34.0 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO83984.1 - 2.3e-27 95.4 30.1 2.3e-27 95.4 20.9 2.6 2 1 1 3 3 3 1 Amino acid permease FAD_binding_6 PF00970.19 GAO83985.1 - 3.1e-08 33.6 0.0 1.2e-07 31.7 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAO83985.1 - 4.7e-07 30.3 0.0 0.0032 18.0 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAO83985.1 - 0.047 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.14 GAO83986.1 - 2.8e-31 108.6 0.0 1e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.1 GAO83986.1 - 0.019 14.2 0.1 0.042 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Ank_2 PF12796.2 GAO83987.1 - 1.3e-86 285.0 22.6 5.3e-22 77.9 1.6 7.0 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO83987.1 - 3.9e-82 266.2 35.5 8.4e-09 34.8 0.0 13.8 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAO83987.1 - 5.7e-64 211.4 28.0 1.9e-09 37.7 0.0 8.5 6 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO83987.1 - 1.8e-56 182.4 26.4 0.00012 21.9 0.1 14.4 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 GAO83987.1 - 4.2e-56 185.7 37.1 1e-09 38.3 0.1 11.0 3 3 9 12 12 12 12 Ankyrin repeats (many copies) FH2 PF02181.18 GAO83988.1 - 5.1e-87 292.1 1.4 5.1e-87 292.1 1.0 2.6 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAO83988.1 - 2.4e-70 235.7 0.7 5e-70 234.6 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAO83988.1 - 1.2e-53 181.4 1.1 5e-52 176.1 0.2 3.0 1 1 1 2 2 2 1 Diaphanous FH3 Domain TrmE_N PF10396.4 GAO83988.1 - 2.1e-35 121.1 0.0 6e-35 119.6 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 GAO83988.1 - 1.2e-21 76.8 2.7 4.3e-21 75.0 0.0 3.0 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 GAO83988.1 - 1.9e-17 63.2 0.1 4.8e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO83988.1 - 1.6e-06 27.6 0.0 0.00044 19.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAO83988.1 - 5.8e-05 22.9 1.3 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 GAO83988.1 - 9.9e-05 21.6 0.0 0.00027 20.2 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 GAO83988.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein DPM3 PF08285.6 GAO83989.1 - 0.078 12.8 0.3 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2422 PF10337.4 GAO83989.1 - 0.095 11.4 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) 2-Hacid_dh_C PF02826.14 GAO83990.1 - 2e-50 170.4 0.0 3.4e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO83990.1 - 1.1e-15 57.2 0.0 1.7e-15 56.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAO83990.1 - 0.004 17.0 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase tRNA-synt_1 PF00133.17 GAO83991.1 - 3.3e-57 193.8 0.0 1.2e-35 122.6 0.0 6.6 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 GAO83991.1 - 2.5e-39 134.4 0.0 4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Suc_Fer-like PF06999.7 GAO83991.1 - 4.5e-33 115.2 0.0 1.2e-32 113.8 0.0 1.7 2 0 0 2 2 2 1 Sucrase/ferredoxin-like tRNA-synt_1g PF09334.6 GAO83991.1 - 6.7e-31 107.3 0.1 3.3e-25 88.5 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAO83991.1 - 1.2e-11 44.6 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 GAO83991.1 - 0.0019 17.0 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Abi PF02517.11 GAO83992.1 - 4e-12 46.1 4.8 4e-12 46.1 3.3 2.8 2 1 0 2 2 2 1 CAAX protease self-immunity Synaptobrevin PF00957.16 GAO83993.1 - 0.84 9.2 2.1 0.65 9.6 0.1 1.7 2 0 0 2 2 2 0 Synaptobrevin MBOAT PF03062.14 GAO83994.1 - 5.9e-45 153.7 5.0 1e-44 153.0 3.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 GAO83995.1 - 2.9e-151 504.9 0.0 3.3e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Abhydrolase_4 PF08386.5 GAO83995.1 - 0.0027 17.5 0.1 2.9 7.8 0.0 2.7 2 1 0 2 2 2 2 TAP-like protein B12-binding PF02310.14 GAO83995.1 - 0.054 13.3 0.2 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain adh_short PF00106.20 GAO83996.1 - 6.3e-24 84.7 0.0 9.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO83996.1 - 5.7e-14 52.1 0.0 8.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO83996.1 - 8.5e-07 28.6 0.0 2.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO83996.1 - 5.2e-05 22.2 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAO83996.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAO83996.1 - 0.00069 18.5 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAO83996.1 - 0.0024 16.6 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Synaptonemal_3 PF15191.1 GAO83996.1 - 0.0025 17.4 0.1 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 NmrA PF05368.8 GAO83996.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 GAO83996.1 - 0.065 12.1 0.0 2.5 6.9 0.0 2.5 1 1 1 2 2 2 0 Male sterility protein DapB_N PF01113.15 GAO83996.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAO83996.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TRAPPC9-Trs120 PF08626.6 GAO83997.1 - 5.3e-152 507.6 0.0 8.6e-152 506.9 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3684 PF12449.3 GAO83998.1 - 0 1599.7 0.0 0 1599.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 GAO83998.1 - 2.8e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAO83998.1 - 0.0064 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 GAO83998.1 - 0.095 12.5 4.3 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 WLM domain Chorismate_bind PF00425.13 GAO83999.1 - 4.2e-65 219.6 0.0 1e-63 215.0 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 GAO83999.1 - 4.8e-27 94.6 0.0 1.6e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 GAO83999.1 - 1.3e-12 47.9 0.0 3.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 GAO83999.1 - 0.00013 21.5 0.0 0.00031 20.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Med6 PF04934.9 GAO84000.1 - 4.1e-42 143.0 0.0 6.3e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 GAO84001.1 - 4.2e-28 97.7 0.0 6.7e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 GAO84002.1 - 4.8e-51 172.7 0.1 6.4e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAO84002.1 - 2.8e-12 45.7 0.3 4.4e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 GAO84003.1 - 7.8e-42 141.8 5.9 1.2e-41 141.1 4.1 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4047 PF13256.1 GAO84003.1 - 0.088 12.7 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) UPF0220 PF05255.6 GAO84004.1 - 8.1e-69 230.1 3.5 9e-69 229.9 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.5 GAO84005.1 - 8.1e-38 128.8 5.9 6.2e-37 125.9 2.6 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 GAO84005.1 - 1.2e-11 44.7 2.6 5.9e-06 26.4 0.1 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 GAO84005.1 - 2.2e-08 34.3 0.1 4.2e-06 27.0 0.0 2.7 3 2 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 GAO84005.1 - 4.1e-06 26.4 0.1 0.017 15.1 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 GAO84005.1 - 9.2e-06 25.3 0.0 0.002 17.9 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat AAA_22 PF13401.1 GAO84005.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Phage_int_SAM_1 PF02899.12 GAO84005.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Actin PF00022.14 GAO84006.1 - 5.6e-159 528.7 0.0 6.3e-159 528.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAO84006.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GARS_A PF01071.14 GAO84007.1 - 6e-85 283.7 0.0 1e-84 282.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 GAO84007.1 - 1.5e-35 121.5 0.1 9.2e-35 119.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 GAO84007.1 - 3.3e-29 101.8 0.0 9.6e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 GAO84007.1 - 9.6e-27 93.0 0.0 2.2e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 GAO84007.1 - 3e-16 59.4 4.6 3.3e-16 59.2 1.6 2.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 GAO84007.1 - 4.3e-09 36.3 0.0 1.1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAO84007.1 - 3.7e-08 32.5 0.0 7.3e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAO84007.1 - 3e-05 23.4 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAO84007.1 - 0.00011 22.0 0.1 0.00044 20.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAO84007.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 GAO84007.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Pet127 PF08634.5 GAO84008.1 - 3.4e-125 416.7 0.2 5.2e-125 416.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.1 GAO84009.1 - 0.19 11.8 14.1 48 4.4 0.0 8.6 11 0 0 11 11 11 0 Leucine Rich repeat LRR_7 PF13504.1 GAO84009.1 - 3.8 8.1 14.1 1.3e+02 3.5 0.0 7.7 10 0 0 10 10 10 0 Leucine rich repeat IGPD PF00475.13 GAO84011.1 - 1.4e-56 190.3 0.5 2e-56 189.8 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TcpQ PF10671.4 GAO84011.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Gly_transf_sug PF04488.10 GAO84013.1 - 4.5e-19 68.7 0.0 9.2e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 GAO84013.1 - 0.025 13.7 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DER1 PF04511.10 GAO84014.1 - 3.5e-50 170.2 4.5 4e-50 170.0 3.1 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 GAO84015.1 - 3e-28 97.7 0.2 4.2e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAO84015.1 - 0.00065 19.8 0.1 0.00093 19.3 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAO84015.1 - 0.011 15.7 0.4 0.025 14.6 0.3 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 GAO84015.1 - 0.018 14.3 1.5 0.03 13.5 1.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Cohesin_load PF10345.4 GAO84016.1 - 3.2e-171 570.6 3.1 3.9e-171 570.3 2.1 1.1 1 0 0 1 1 1 1 Cohesin loading factor DUF3323 PF11796.3 GAO84016.1 - 0.0025 17.1 1.5 0.0056 16.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) Apc5 PF12862.2 GAO84016.1 - 0.013 15.2 1.0 0.054 13.3 0.7 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 F-box-like PF12937.2 GAO84016.1 - 0.03 14.0 0.5 0.03 14.0 0.4 3.0 3 0 0 3 3 3 0 F-box-like TPR_4 PF07721.9 GAO84016.1 - 0.038 14.3 0.4 17 6.1 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box PF00646.28 GAO84016.1 - 0.044 13.4 1.7 0.11 12.1 1.2 1.7 1 0 0 1 1 1 0 F-box domain TPR_12 PF13424.1 GAO84016.1 - 1.5 8.8 15.3 4 7.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAO84017.1 - 4.4e-13 49.6 0.2 7.6e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO84017.1 - 7.8e-11 41.9 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO84017.1 - 4.8e-05 23.1 0.0 0.00014 21.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAO84017.1 - 0.043 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase RNA_pol_L_2 PF13656.1 GAO84019.1 - 4e-31 106.2 0.0 7.1e-31 105.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAO84019.1 - 6.2e-14 50.8 0.0 1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF947 PF06102.7 GAO84021.1 - 1.3e-48 164.9 21.0 1.3e-48 164.9 14.5 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF947) NIF PF03031.13 GAO84022.1 - 2.5e-24 85.7 0.0 3.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.14 GAO84023.1 - 1.9e-44 149.7 0.1 3.8e-44 148.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 GAO84023.1 - 3.1e-11 43.0 0.2 9.2e-11 41.5 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO84023.1 - 3.4e-09 36.7 0.0 9.8e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO84023.1 - 1.7e-08 34.2 0.1 1.7e-08 34.2 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO84023.1 - 5e-07 29.8 0.0 1.7e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO84023.1 - 8.4e-06 26.2 0.2 2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO84023.1 - 0.00061 19.7 0.0 0.0037 17.2 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain TPR_2 PF07719.12 GAO84023.1 - 0.27 11.2 2.0 0.39 10.7 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.14 GAO84024.1 - 2.6e-38 130.9 0.1 4.2e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3391 PF11871.3 GAO84025.1 - 0.0034 17.6 0.2 0.0066 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) PAT1 PF09770.4 GAO84025.1 - 0.23 9.6 21.5 0.3 9.2 14.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.27 GAO84026.1 - 2.2e-26 89.1 13.4 1.4e-07 30.2 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAO84026.1 - 1.9e-22 79.1 3.6 3.3e-12 46.3 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAO84026.1 - 5.9e-20 69.3 6.4 6.1e-05 22.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAO84026.1 - 2.1e-18 64.7 13.6 1.8e-06 27.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAO84026.1 - 9.7e-14 50.7 15.8 6.3e-05 22.5 0.7 4.7 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAO84026.1 - 4.7e-07 29.8 0.0 0.00052 20.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAO84026.1 - 0.00057 19.5 10.2 0.46 10.2 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.5 GAO84026.1 - 0.024 13.7 0.7 0.059 12.4 0.1 1.7 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.1 GAO84026.1 - 0.026 14.4 0.1 0.83 9.6 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.4 GAO84027.1 - 1.1e-31 110.2 1.1 1.1e-31 110.2 0.8 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like SET PF00856.23 GAO84028.1 - 1.1e-16 61.5 0.0 7.3e-16 58.9 0.0 2.2 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 GAO84028.1 - 1.6e-08 34.5 2.5 5.6e-08 32.7 1.7 1.9 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding CENP-B_dimeris PF09026.5 GAO84028.1 - 0.85 9.8 6.0 16 5.8 4.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M22 PF00814.20 GAO84029.1 - 1.1e-85 287.4 0.0 1.2e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.10 GAO84030.1 - 1.8e-28 98.3 0.1 5.1e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 GAO84030.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Gti1_Pac2 PF09729.4 GAO84031.1 - 1.6e-63 213.5 0.0 3.3e-63 212.5 0.0 1.5 2 0 0 2 2 2 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 GAO84033.1 - 7.4e-17 61.5 4.6 1.5e-16 60.4 3.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Mannosyl_trans3 PF11051.3 GAO84034.1 - 7.1e-80 268.2 0.1 2.3e-79 266.5 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative GIDA PF01134.17 GAO84035.1 - 5.8e-153 509.3 0.0 7.3e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 GAO84035.1 - 4.7e-19 68.2 0.0 1.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 GAO84035.1 - 3.1e-08 33.7 0.7 6.5e-08 32.6 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO84035.1 - 5.2e-07 29.0 0.9 8.8e-07 28.3 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAO84035.1 - 6.5e-06 25.2 1.5 0.014 14.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO84035.1 - 0.0011 17.8 1.5 0.0011 17.8 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 GAO84035.1 - 0.015 14.8 0.6 0.028 13.9 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 GAO84035.1 - 0.021 13.4 0.5 3.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 GAO84035.1 - 0.023 13.1 2.0 0.11 10.9 0.3 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 GAO84035.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO84035.1 - 0.054 13.9 0.2 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ARD PF03079.9 GAO84036.1 - 2.4e-46 157.5 0.6 2.9e-46 157.2 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 GAO84036.1 - 6.2e-10 38.4 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 GAO84036.1 - 8.2e-07 28.7 0.1 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 GAO84036.1 - 0.0063 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF2404 PF10296.4 GAO84037.1 - 4.5e-05 23.4 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1183 PF06682.7 GAO84038.1 - 7.5e-70 236.0 0.0 9.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Myb_DNA-binding PF00249.26 GAO84039.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 GAO84040.1 - 1.6e-30 104.8 13.1 1.6e-30 104.8 9.1 7.5 6 2 3 9 9 9 1 BRE1 E3 ubiquitin ligase PSD2 PF07624.6 GAO84040.1 - 0.1 12.2 2.9 0.39 10.3 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1585) Baculo_PEP_C PF04513.7 GAO84040.1 - 6.9 6.5 35.4 5.9 6.7 4.9 5.8 4 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus UreF PF01730.11 GAO84041.1 - 5.8e-14 52.4 1.0 2e-13 50.6 0.7 1.8 1 1 0 1 1 1 1 UreF ABC1 PF03109.11 GAO84042.1 - 2e-33 114.8 0.0 6.2e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 ABC1 family MCH PF02289.11 GAO84042.1 - 0.048 12.6 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) ABC2_membrane PF01061.19 GAO84043.1 - 1.4e-90 302.1 58.7 2.8e-48 163.8 14.0 2.9 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAO84043.1 - 8.5e-40 136.2 0.7 5.6e-21 75.2 0.0 3.1 4 0 0 4 4 2 2 ABC transporter PDR_CDR PF06422.7 GAO84043.1 - 1.4e-32 111.3 2.2 4.4e-27 93.7 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 GAO84043.1 - 1.6e-07 31.3 0.0 5.4e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 GAO84043.1 - 1e-06 28.0 10.3 1e-06 28.0 7.1 3.1 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAO84043.1 - 2.3e-06 27.7 0.1 0.098 12.6 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO84043.1 - 5.5e-06 25.9 0.2 0.16 11.3 0.1 2.8 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 GAO84043.1 - 1.4e-05 24.5 0.4 0.00017 21.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO84043.1 - 5.2e-05 23.1 0.7 0.0068 16.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAO84043.1 - 5.7e-05 23.1 0.1 0.0051 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAO84043.1 - 6.3e-05 22.2 0.1 0.0014 17.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO84043.1 - 6.9e-05 22.9 0.0 0.079 13.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 GAO84043.1 - 0.00017 21.8 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO84043.1 - 0.00051 19.5 2.4 0.86 9.0 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_28 PF13521.1 GAO84043.1 - 0.00059 19.8 0.0 0.0022 17.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 GAO84043.1 - 0.00075 18.9 0.3 0.23 11.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAO84043.1 - 0.0011 18.9 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 GAO84043.1 - 0.0014 18.2 1.9 0.089 12.4 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 GAO84043.1 - 0.0014 19.4 0.0 0.009 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAO84043.1 - 0.0034 17.0 0.5 0.23 11.1 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 GAO84043.1 - 0.0056 16.2 1.9 0.6 9.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAO84043.1 - 0.012 15.1 0.3 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 GAO84043.1 - 0.031 13.5 0.1 0.33 10.1 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAO84043.1 - 0.038 14.4 0.2 0.86 10.1 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein Septin PF00735.13 GAO84043.1 - 0.043 12.8 0.2 0.31 9.9 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 GAO84043.1 - 0.062 13.2 0.7 1.5 8.7 0.1 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 GAO84043.1 - 0.13 11.1 0.5 6.1 5.6 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 GAO84043.1 - 0.13 12.4 0.2 9 6.5 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 GAO84043.1 - 0.17 10.9 0.0 19 4.1 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 GAO84043.1 - 0.26 10.7 0.8 0.5 9.8 0.2 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 GAO84043.1 - 0.34 9.7 0.6 4.3 6.1 0.1 2.4 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 GAO84043.1 - 3.6 7.1 6.8 3.1 7.3 0.3 2.9 3 0 0 3 3 3 0 AAA domain Tyr-DNA_phospho PF06087.7 GAO84044.1 - 2.3e-101 339.6 0.0 2.8e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 GAO84044.1 - 0.00011 21.4 10.9 0.00013 21.2 1.1 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif PLDc_2 PF13091.1 GAO84044.1 - 0.0004 20.1 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain HA2 PF04408.18 GAO84046.1 - 5.1e-20 71.4 0.0 2.6e-19 69.1 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAO84046.1 - 5.8e-15 54.9 0.0 5.5e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAO84046.1 - 2.1e-11 43.6 0.0 7.3e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 GAO84046.1 - 6.1e-11 42.1 0.6 6.4e-10 38.7 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO84046.1 - 8.5e-05 22.7 0.0 0.0004 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 GAO84046.1 - 0.0044 16.8 12.4 0.091 12.5 0.0 3.8 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit T2SE PF00437.15 GAO84046.1 - 0.013 14.3 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 GAO84046.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain TFIIA PF03153.8 GAO84046.1 - 1.3 8.8 30.3 0.033 14.0 15.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dsh_C PF12316.3 GAO84046.1 - 7.4 6.6 13.6 0.015 15.3 1.7 2.3 2 1 1 3 3 3 0 Segment polarity protein dishevelled (Dsh) C terminal cwf21 PF08312.7 GAO84047.1 - 5.6e-17 61.3 21.2 5.6e-17 61.3 14.7 1.9 2 0 0 2 2 2 1 cwf21 domain PUF PF00806.14 GAO84048.1 - 4e-63 205.4 13.2 1.3e-09 37.0 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 GAO84048.1 - 0.0034 17.6 0.3 3.6 7.9 0.1 4.1 2 2 2 4 4 4 1 Protein of unknown function DUF260 DUF234 PF03008.9 GAO84048.1 - 0.14 12.3 1.8 1.4 9.0 0.1 2.7 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function IncA PF04156.9 GAO84049.1 - 0.038 13.6 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 IncA protein SMP_2 PF10144.4 GAO84049.1 - 0.047 12.8 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUF3377 PF11857.3 GAO84049.1 - 0.061 12.9 0.1 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SP_C-Propep PF08999.5 GAO84049.1 - 0.071 12.5 0.2 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Phosphodiest PF01663.17 GAO84050.1 - 3.6e-15 56.1 0.8 9e-15 54.8 0.6 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAO84050.1 - 9.4e-07 28.3 0.1 1.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 GAO84050.1 - 2.3e-06 27.2 0.2 3.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sugar_tr PF00083.19 GAO84052.1 - 6.7e-86 288.6 28.9 9.5e-86 288.1 20.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84052.1 - 4.8e-24 84.7 38.7 2.1e-23 82.6 26.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 GAO84052.1 - 0.0072 15.7 3.7 0.99 8.7 0.4 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF4131) Mso1_Sec1_bdg PF14475.1 GAO84053.1 - 9.5e-10 37.7 0.0 1.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 GAO84054.1 - 1.6e-31 109.0 0.3 3.2e-31 108.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 GAO84054.1 - 1.2e-23 83.0 12.6 1.2e-23 83.0 8.8 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 GAO84054.1 - 8.6e-06 25.0 12.8 1.1e-05 24.7 8.8 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 GAO84054.1 - 0.078 10.8 30.2 0.1 10.4 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 GAO84054.1 - 0.14 11.3 14.2 0.19 10.9 9.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 GAO84054.1 - 1.7 6.8 29.4 2.6 6.3 20.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.7 GAO84054.1 - 9.9 4.3 28.9 53 1.9 0.0 2.0 1 1 1 2 2 2 0 Mpp10 protein DUF3402 PF11882.3 GAO84055.1 - 1.6e-166 554.3 0.0 2.4e-166 553.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 GAO84055.1 - 1e-105 352.8 0.0 1.5e-105 352.2 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 GAO84055.1 - 4.7e-13 48.9 2.7 1.1e-12 47.7 1.9 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 GAO84055.1 - 0.14 11.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family RWD PF05773.17 GAO84056.1 - 1.3e-23 83.0 0.0 2.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 GAO84056.1 - 4e-19 68.2 36.3 1.5e-14 53.6 1.5 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 GAO84056.1 - 0.001 18.8 10.9 0.001 18.8 7.5 3.7 2 1 1 3 3 3 2 Ring finger domain CRT10 PF08728.5 GAO84057.1 - 1.7e-20 72.6 0.0 4.6e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 CRT10 MMtag PF10159.4 GAO84058.1 - 2.8e-34 116.9 6.4 2.8e-34 116.9 4.5 1.9 2 0 0 2 2 2 1 Kinase phosphorylation protein TBX PF12598.3 GAO84058.1 - 0.18 12.2 4.2 0.27 11.6 2.9 1.2 1 0 0 1 1 1 0 T-box transcription factor RR_TM4-6 PF06459.7 GAO84058.1 - 0.48 10.2 5.3 0.63 9.8 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_63 PF03200.11 GAO84059.1 - 4.5e-248 825.2 0.0 4e-247 822.0 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 GAO84059.1 - 1e-06 27.6 0.2 1.9e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 GAO84059.1 - 0.012 13.8 0.0 0.024 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DAO PF01266.19 GAO84060.1 - 2.1e-61 207.8 0.2 2.8e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO84060.1 - 1.1e-06 28.5 0.1 2.4e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO84060.1 - 8.7e-05 21.5 0.1 0.022 13.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAO84060.1 - 0.00012 22.0 0.2 0.34 10.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO84060.1 - 0.00092 17.9 0.3 0.0034 16.0 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAO84060.1 - 0.0022 18.3 0.2 0.0058 17.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO84060.1 - 0.011 15.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO84060.1 - 0.024 13.7 0.1 0.045 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAO84060.1 - 0.058 13.1 0.2 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 GAO84060.1 - 0.13 11.0 0.0 4.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Strep_67kDa_ant PF06100.6 GAO84060.1 - 0.18 10.1 0.1 0.27 9.5 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Mqo PF06039.10 GAO84060.1 - 0.21 9.7 0.0 4.6 5.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF1777 PF08648.7 GAO84061.1 - 1.1e-20 74.1 70.0 5.5e-18 65.3 48.5 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Elong_Iki1 PF10483.4 GAO84062.1 - 1e-84 284.2 0.0 2.3e-83 279.8 0.0 2.0 1 1 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 GAO84063.1 - 2.7e-30 103.7 0.5 4e-30 103.2 0.4 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAO84063.1 - 8.9e-14 50.8 0.0 1.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin PilJ PF13675.1 GAO84063.1 - 0.4 11.0 3.3 3.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ASXH PF13919.1 GAO84064.1 - 2.9e-42 143.7 6.7 2.9e-42 143.7 4.6 1.7 2 0 0 2 2 2 1 Asx homology domain adh_short PF00106.20 GAO84065.1 - 1.1e-13 51.4 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84065.1 - 2.2e-09 37.4 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84065.1 - 3.7e-05 23.4 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAO84065.1 - 0.0064 15.6 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CLPTM1 PF05602.7 GAO84066.1 - 9.3e-177 588.1 0.0 1.1e-176 587.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 GAO84066.1 - 0.85 9.8 5.8 0.26 11.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) CENP-I PF07778.6 GAO84067.1 - 2.8e-89 299.6 0.3 3.9e-89 299.1 0.2 1.1 1 0 0 1 1 1 1 Mis6 DUF2659 PF10858.3 GAO84067.1 - 0.066 12.6 0.5 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2659) Transcrip_reg PF01709.15 GAO84068.1 - 6.3e-63 212.0 2.0 7.2e-63 211.8 1.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator AhpC-TSA_2 PF13911.1 GAO84068.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Clp1 PF06807.9 GAO84068.1 - 0.06 13.1 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 HEAT_2 PF13646.1 GAO84069.1 - 3.1e-15 56.2 6.7 0.0013 18.9 0.0 8.1 6 1 0 6 6 6 5 HEAT repeats HEAT PF02985.17 GAO84069.1 - 3e-07 29.9 18.4 1.5 9.0 0.0 10.3 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 GAO84069.1 - 0.0039 17.5 0.0 7.9 6.9 0.0 4.3 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Ribonuc_L-PSP PF01042.16 GAO84069.1 - 0.021 14.5 1.6 0.11 12.2 0.1 2.8 2 1 0 2 2 2 0 Endoribonuclease L-PSP Vps51 PF08700.6 GAO84070.1 - 1.1e-15 57.2 0.0 6.9e-15 54.6 0.0 2.6 1 0 0 1 1 1 1 Vps51/Vps67 DUF1640 PF07798.6 GAO84070.1 - 6e-13 49.2 9.0 8.1e-13 48.7 3.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) D123 PF07065.9 GAO84071.1 - 2.2e-90 302.7 0.0 3.3e-88 295.6 0.0 2.1 1 1 0 1 1 1 1 D123 ECH PF00378.15 GAO84072.1 - 1.8e-28 99.3 0.0 2.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 GAO84073.1 - 0.00022 21.0 3.9 0.00044 20.0 2.7 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) TMEM247 PF15444.1 GAO84073.1 - 0.16 11.7 1.1 0.19 11.5 0.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DUF4574 PF15141.1 GAO84074.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) DUF3317 PF11779.3 GAO84074.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) RF-1 PF00472.15 GAO84075.1 - 1.4e-25 89.3 3.8 2.5e-25 88.5 2.6 1.3 1 0 0 1 1 1 1 RF-1 domain DUF883 PF05957.8 GAO84075.1 - 0.036 14.4 6.4 0.07 13.5 4.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PBP_sp32 PF07222.7 GAO84075.1 - 2.9 6.9 7.2 0.39 9.8 2.3 1.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 CAS_CSE1 PF03378.10 GAO84076.1 - 6.2e-194 644.2 0.0 1.5e-193 643.0 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 GAO84076.1 - 1.4e-155 517.4 0.9 2e-155 516.9 0.6 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 GAO84076.1 - 1.5e-14 53.6 0.2 6.2e-14 51.6 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAO84076.1 - 0.0087 15.9 0.7 1.1 9.1 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein DUF1529 PF07485.6 GAO84076.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) HEAT PF02985.17 GAO84076.1 - 0.46 10.7 2.5 35 4.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat DUF3384 PF11864.3 GAO84077.1 - 1.3e-115 386.5 1.0 2.2e-115 385.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 GAO84077.1 - 2.9e-54 183.3 0.0 4.8e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 GAO84077.1 - 1.7e-31 109.5 0.3 3.1e-26 92.3 0.0 3.2 3 0 0 3 3 3 3 Tuberin GAS2 PF02187.12 GAO84078.1 - 1.3e-05 24.8 0.1 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hexokinase_2 PF03727.11 GAO84079.1 - 7.1e-72 241.5 0.0 1e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAO84079.1 - 4.6e-60 202.4 0.0 6.2e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hus1 PF04005.7 GAO84080.1 - 2.9e-110 367.8 0.0 3.6e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 GAO84081.1 - 5e-105 351.3 0.0 6.7e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 GAO84081.1 - 2.3e-73 247.1 18.2 2.3e-73 247.1 12.6 4.3 4 1 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 GAO84081.1 - 8.8e-33 112.7 0.0 2e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 GAO84082.1 - 9.1e-18 64.1 0.0 4.5e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAO84082.1 - 2.6e-15 57.4 0.0 1.3e-14 55.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO84082.1 - 4.4e-10 40.0 0.0 1.1e-09 38.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO84082.1 - 2.7e-06 27.2 0.0 8.1e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO84082.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.13 GAO84083.1 - 5.4e-40 137.1 1.0 1e-39 136.2 0.7 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 GAO84083.1 - 2.5e-12 46.5 0.0 2.4e-08 33.5 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) Ring_hydroxyl_A PF00848.14 GAO84084.1 - 1.6e-38 132.4 5.6 1.3e-27 96.8 1.3 4.3 2 2 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Mpv17_PMP22 PF04117.7 GAO84084.1 - 1.1e-21 76.1 0.2 2.1e-21 75.3 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Rieske PF00355.21 GAO84084.1 - 4.3e-16 58.2 0.0 9.1e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain F-box-like PF12937.2 GAO84085.1 - 5.4e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO84085.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain PurS PF02700.9 GAO84085.1 - 0.22 11.5 0.0 0.49 10.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Catalase PF00199.14 GAO84086.1 - 5.8e-165 548.6 0.7 7.5e-165 548.2 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAO84086.1 - 2.4e-17 62.5 0.1 4.7e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 GAO84086.1 - 2.3e-05 23.9 0.0 6.5e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.1 GAO84087.1 - 1.6e-23 82.4 11.2 2.7e-11 43.2 0.5 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAO84087.1 - 1.1e-11 44.2 3.0 0.011 15.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAO84087.1 - 6.5e-08 31.7 3.4 0.29 11.0 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO84087.1 - 1.1e-05 24.9 12.9 0.36 10.8 0.0 7.3 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO84087.1 - 1.7e-05 25.3 12.0 0.018 15.7 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO84087.1 - 0.00016 21.9 10.8 14 6.6 0.1 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 GAO84087.1 - 0.00072 19.7 4.6 0.0052 17.0 0.4 3.5 2 0 0 2 2 2 1 C2H2-type zinc finger TPR_11 PF13414.1 GAO84087.1 - 0.0012 18.3 7.0 0.21 11.2 0.4 4.6 3 2 3 6 6 6 2 TPR repeat TPR_1 PF00515.23 GAO84087.1 - 0.0019 17.7 0.6 0.097 12.3 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-MYND PF01753.13 GAO84087.1 - 0.0025 17.6 7.3 0.0025 17.6 5.1 3.2 3 1 0 3 3 3 1 MYND finger HypA PF01155.14 GAO84087.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.5 3 0 0 3 3 1 0 Hydrogenase expression/synthesis hypA family TPR_8 PF13181.1 GAO84087.1 - 0.014 15.1 3.8 0.081 12.7 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 GAO84087.1 - 0.015 15.4 4.9 1.2 9.4 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO84087.1 - 0.028 14.6 5.3 0.26 11.5 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TPR_19 PF14559.1 GAO84087.1 - 0.14 12.4 4.1 11 6.4 0.6 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Lar_restr_allev PF14354.1 GAO84087.1 - 5.8 7.3 10.4 0.18 12.1 0.3 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar MFS_1 PF07690.11 GAO84088.1 - 6.5e-38 130.3 22.3 2.9e-27 95.3 1.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84088.1 - 1.6e-12 46.7 2.1 1.6e-12 46.7 1.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 GAO84088.1 - 1.1e-10 40.5 0.0 1.2e-06 27.2 0.6 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAO84088.1 - 3.3e-05 23.6 0.4 0.0038 16.9 0.1 2.9 2 0 0 2 2 2 1 MFS_1 like family TRI12 PF06609.8 GAO84088.1 - 0.0026 16.0 0.4 0.0044 15.2 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 GAO84088.1 - 0.01 14.4 4.7 0.24 9.8 0.2 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 GAO84088.1 - 2.7 5.9 9.3 0.088 10.9 1.1 2.3 3 0 0 3 3 3 0 Transmembrane secretion effector SRP-alpha_N PF04086.8 GAO84089.1 - 1.1e-88 297.2 0.0 1.5e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 GAO84089.1 - 2.1e-50 170.8 0.0 3.6e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 GAO84089.1 - 2.9e-07 30.5 0.1 2.3e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 GAO84089.1 - 6.1e-06 25.7 0.1 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 GAO84089.1 - 1.1e-05 24.4 0.0 1.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 GAO84089.1 - 0.00037 20.1 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAO84089.1 - 0.0024 17.3 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 GAO84089.1 - 0.0045 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 GAO84089.1 - 0.031 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 GAO84089.1 - 0.043 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAO84089.1 - 0.073 12.9 0.2 0.57 10.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAO84089.1 - 0.086 12.8 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.9 GAO84089.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_21 PF13304.1 GAO84089.1 - 0.096 12.6 0.8 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO84089.1 - 0.12 12.4 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.10 GAO84090.1 - 6.2e-75 251.4 4.2 7.5e-75 251.1 2.9 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 GAO84090.1 - 0.077 12.4 13.2 0.024 14.1 6.7 1.8 1 1 1 2 2 2 0 Yip1 domain Ribosomal_L14e PF01929.12 GAO84091.1 - 1.9e-25 88.9 0.2 3.1e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 GAO84091.1 - 3.5e-06 26.5 0.1 6.5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.13 GAO84092.1 - 1.1e-20 72.8 0.2 1.7e-09 37.0 0.0 3.2 2 1 1 3 3 3 2 NAC domain UBA PF00627.26 GAO84092.1 - 8.6e-05 22.2 0.5 0.00016 21.3 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF4407 PF14362.1 GAO84092.1 - 0.14 11.0 2.0 0.19 10.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 GAO84092.1 - 0.43 8.5 8.8 0.0063 14.6 1.4 1.3 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.2 GAO84092.1 - 4.2 6.8 11.4 0.8 9.1 4.6 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein Mt_ATP-synt_D PF05873.7 GAO84093.1 - 2.4e-17 63.0 1.1 3e-17 62.7 0.7 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Acylphosphatase PF00708.13 GAO84093.1 - 0.059 13.4 0.2 1.7 8.8 0.0 2.3 1 1 1 2 2 2 0 Acylphosphatase AAA_13 PF13166.1 GAO84093.1 - 0.077 11.4 2.4 0.086 11.2 1.7 1.1 1 0 0 1 1 1 0 AAA domain Oxysterol_BP PF01237.13 GAO84093.1 - 0.078 11.4 0.7 0.088 11.2 0.5 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Syntaxin PF00804.20 GAO84093.1 - 0.11 12.6 1.4 0.17 12.0 0.9 1.3 1 0 0 1 1 1 0 Syntaxin Tropomyosin_1 PF12718.2 GAO84093.1 - 0.62 9.9 5.8 4.8 7.0 2.1 2.3 2 1 0 2 2 2 0 Tropomyosin like PhoU PF01895.14 GAO84093.1 - 1.1 9.7 4.2 6.4 7.2 0.4 2.6 2 2 0 2 2 2 0 PhoU domain F-box-like PF12937.2 GAO84094.1 - 0.87 9.3 7.8 22 4.8 0.0 3.2 2 1 0 2 2 2 0 F-box-like Aldedh PF00171.17 GAO84095.1 - 1.1e-121 406.4 0.0 1.4e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.20 GAO84096.1 - 6.1e-07 29.6 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAO84096.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif GATase_2 PF00310.16 GAO84097.1 - 1.9e-20 72.9 0.0 4e-15 55.4 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAO84097.1 - 9.8e-15 54.6 0.0 1.9e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 GAO84097.1 - 4.2e-13 49.0 0.1 9.3e-13 47.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 GAO84097.1 - 5.2e-13 48.8 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAO84097.1 - 1.7e-05 23.6 0.0 3.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 GAO84097.1 - 0.037 13.3 0.0 0.098 11.9 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_methylase PF00145.12 GAO84098.1 - 8.7e-45 153.2 0.0 1.1e-32 113.5 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DUF3403 PF11883.3 GAO84098.1 - 0.69 10.2 4.1 0.55 10.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) MmgE_PrpD PF03972.9 GAO84099.1 - 3e-152 506.8 0.0 3.4e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DHC_N1 PF08385.7 GAO84099.1 - 0.044 12.1 0.0 0.063 11.6 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 MFS_1 PF07690.11 GAO84100.1 - 5e-35 120.8 37.9 1.5e-32 112.6 25.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.23 GAO84101.1 - 7e-09 35.4 0.2 1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO84101.1 - 1.4e-08 34.4 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain YebF PF13995.1 GAO84101.1 - 0.26 11.3 1.2 0.75 9.8 0.2 2.1 1 1 1 2 2 2 0 YebF-like protein Fungal_trans_2 PF11951.3 GAO84102.1 - 3.5e-17 62.0 0.6 1.2e-10 40.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Biliv-reduc_cat PF09166.5 GAO84103.1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Biliverdin reductase, catalytic E1-E2_ATPase PF00122.15 GAO84104.1 - 7.5e-66 221.4 1.9 1.5e-65 220.4 1.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO84104.1 - 7.4e-32 110.3 15.3 7.8e-32 110.2 5.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO84104.1 - 2e-29 103.5 0.0 6.2e-29 101.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO84104.1 - 3e-18 65.0 0.0 6.1e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAO84104.1 - 2.7e-16 59.2 0.0 5.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO84104.1 - 5.5e-13 49.5 0.0 1.3e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO84104.1 - 0.0006 19.4 0.1 0.017 14.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 GAO84104.1 - 0.00079 18.0 0.2 0.00079 18.0 0.1 2.9 3 0 0 3 3 3 1 DctM-like transporters ALO PF04030.9 GAO84105.1 - 5.9e-13 49.0 1.1 1.1e-12 48.1 0.8 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.6 GAO84105.1 - 2.8e-07 29.9 1.6 2.3e-05 23.7 1.1 2.3 1 1 0 1 1 1 1 Cholesterol oxidase, substrate-binding FAD_binding_4 PF01565.18 GAO84105.1 - 0.00074 19.0 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAO84106.1 - 2.9e-27 95.8 0.1 4e-26 92.1 0.1 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO84106.1 - 2.4e-15 56.6 0.1 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 GAO84106.1 - 1.9e-09 37.8 0.0 1.1e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Pyr_redox_dim PF02852.17 GAO84106.1 - 9.4e-08 32.0 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Amino_oxidase PF01593.19 GAO84106.1 - 1.6e-05 24.2 0.4 0.26 10.2 0.1 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 GAO84106.1 - 0.00016 21.9 0.3 0.0058 16.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAO84106.1 - 0.0002 21.2 2.1 0.17 11.8 0.1 3.3 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO84106.1 - 0.00058 18.4 0.6 5.1 5.4 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 GAO84106.1 - 0.0017 17.3 0.8 1.6 7.5 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 GAO84106.1 - 0.0026 16.7 4.7 0.091 11.6 0.0 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO84106.1 - 0.058 12.4 1.6 0.091 11.8 0.0 2.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO84106.1 - 0.73 8.6 4.3 1.3 7.8 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain zf-RING_2 PF13639.1 GAO84107.1 - 5.5e-06 26.1 9.4 2e-05 24.3 1.6 2.6 2 0 0 2 2 2 2 Ring finger domain FANCL_C PF11793.3 GAO84107.1 - 4.2e-05 23.4 6.5 0.00025 20.9 1.4 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 GAO84107.1 - 0.00067 19.3 0.7 0.00067 19.3 0.5 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 GAO84107.1 - 0.00075 19.5 9.3 0.0032 17.5 6.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 GAO84107.1 - 0.0017 18.0 2.8 0.0073 15.9 2.0 2.1 1 0 0 1 1 1 1 PHD-finger Ribosomal_60s PF00428.14 GAO84107.1 - 0.014 15.7 1.2 0.014 15.7 0.9 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-Apc11 PF12861.2 GAO84107.1 - 0.53 10.1 5.0 0.41 10.5 1.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 GAO84107.1 - 0.57 10.2 6.4 2.6 8.0 4.4 2.1 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 GAO84107.1 - 1.7 8.7 7.0 0.22 11.6 0.5 2.3 2 0 0 2 2 2 0 RING-variant domain Cwf_Cwc_15 PF04889.7 GAO84107.1 - 2 8.0 10.0 3.2 7.3 6.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BATS PF06968.8 GAO84108.1 - 2e-28 98.0 0.0 1.6e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 GAO84108.1 - 1.9e-15 57.4 0.0 3.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily P33MONOX PF15302.1 GAO84108.1 - 0.043 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P33 mono-oxygenase Aminotran_3 PF00202.16 GAO84109.1 - 1e-39 136.3 0.0 5.8e-21 74.7 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 GAO84109.1 - 1.8e-36 125.6 0.0 2.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 GAO84109.1 - 0.07 12.5 0.0 0.34 10.2 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.16 GAO84110.1 - 3.3e-36 125.0 0.0 4.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 GAO84110.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.14 GAO84110.1 - 0.035 12.8 0.0 0.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAO84110.1 - 0.13 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PilJ PF13675.1 GAO84110.1 - 0.13 12.5 0.9 0.45 10.8 0.1 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AMP-binding PF00501.23 GAO84111.1 - 8.7e-77 258.2 0.0 1.1e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO84111.1 - 3.9e-09 37.3 0.1 1.2e-08 35.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 GAO84111.1 - 0.24 10.9 2.1 0.96 9.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) FAD_binding_4 PF01565.18 GAO84112.1 - 1.1e-17 63.8 2.2 2.3e-17 62.7 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO84112.1 - 2.3e-12 46.6 1.2 5.5e-12 45.3 0.5 1.9 2 0 0 2 2 2 1 Berberine and berberine like Citrate_synt PF00285.16 GAO84114.1 - 3e-99 332.1 0.0 3.7e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ABC_tran PF00005.22 GAO84115.1 - 2.1e-47 160.8 0.0 3.6e-25 88.8 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO84115.1 - 3.7e-15 56.6 1.7 0.00056 19.9 0.0 4.2 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 GAO84115.1 - 5.4e-11 42.1 1.6 0.0026 17.0 0.0 4.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAO84115.1 - 1.3e-06 28.9 0.0 0.0032 17.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAO84115.1 - 1.3e-06 27.8 0.8 0.057 12.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAO84115.1 - 1.8e-06 28.4 0.1 0.021 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO84115.1 - 2e-06 27.0 0.1 0.014 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 GAO84115.1 - 2.4e-06 26.8 0.0 0.11 11.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 GAO84115.1 - 3e-06 27.1 0.0 0.044 13.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAO84115.1 - 4.9e-06 26.3 0.0 0.14 12.0 0.0 3.3 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Chromo PF00385.19 GAO84115.1 - 7.7e-06 25.4 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_10 PF12846.2 GAO84115.1 - 1.4e-05 24.6 2.1 1 8.6 0.0 4.2 4 1 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 GAO84115.1 - 2.1e-05 24.6 0.1 0.086 12.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAO84115.1 - 3.6e-05 24.5 0.0 0.69 10.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAO84115.1 - 9.1e-05 22.1 0.5 0.058 13.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 GAO84115.1 - 0.00012 22.0 1.3 0.14 11.9 0.1 3.5 4 0 0 4 4 4 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 GAO84115.1 - 0.00018 21.3 0.2 0.067 13.0 0.0 3.0 2 1 1 3 3 3 1 Dynamin family MobB PF03205.9 GAO84115.1 - 0.00025 20.7 0.1 0.9 9.2 0.0 3.1 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAO84115.1 - 0.00048 20.1 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO84115.1 - 0.0012 18.7 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAO84115.1 - 0.0032 17.6 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 GAO84115.1 - 0.0083 15.6 0.2 2.3 7.6 0.1 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 GAO84115.1 - 0.0093 14.7 0.6 3.1 6.5 0.1 2.4 2 0 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 GAO84115.1 - 0.011 15.1 0.0 5.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.17 GAO84115.1 - 0.023 14.7 0.9 1.2e+02 3.1 0.2 5.4 6 0 0 6 6 5 0 HEAT repeat DUF815 PF05673.8 GAO84115.1 - 0.024 13.5 0.1 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAO84115.1 - 0.03 14.2 0.0 4.1 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAO84115.1 - 0.031 14.4 1.0 1.7 8.8 0.0 3.6 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 GAO84115.1 - 0.035 13.1 0.0 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_25 PF13481.1 GAO84115.1 - 0.041 13.2 0.0 8.1 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 GAO84115.1 - 0.049 12.1 0.5 2.5 6.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 GAO84115.1 - 0.055 12.9 0.0 7.5 5.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 GAO84115.1 - 0.098 11.7 0.2 17 4.4 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 GAO84115.1 - 0.12 12.7 0.0 30 4.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 GAO84115.1 - 0.16 11.6 0.4 0.95 9.1 0.0 2.5 3 0 0 3 3 3 0 Archaeal ATPase Glyco_hydro_3 PF00933.16 GAO84116.1 - 6.8e-85 284.6 0.0 9.8e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO84116.1 - 1.2e-49 168.8 0.0 3.5e-49 167.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO84116.1 - 1.3e-22 79.4 0.9 4.1e-22 77.8 0.6 1.9 1 1 0 1 1 1 1 Fibronectin type III-like domain Gryzun PF07919.7 GAO84116.1 - 0.097 10.9 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Gmx_para_CXXCG PF09535.5 GAO84117.1 - 0.0056 15.7 0.2 0.0072 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (Gmx_para_CXXCG) ATX_III PF08098.6 GAO84117.1 - 0.22 11.3 2.9 5.3 6.9 0.1 3.1 3 0 0 3 3 3 0 Anemonia sulcata toxin III family Malate_synthase PF01274.17 GAO84119.1 - 2.1e-236 784.9 0.0 2.4e-236 784.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 GAO84119.1 - 0.046 12.5 0.0 0.098 11.5 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Gln-synt_C PF00120.19 GAO84120.1 - 1.4e-62 211.1 0.0 1.8e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Herpes_alk_exo PF01771.12 GAO84120.1 - 0.19 10.1 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease adh_short PF00106.20 GAO84121.1 - 1.6e-26 93.1 0.8 2.3e-26 92.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84121.1 - 9.7e-17 61.5 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84121.1 - 1.7e-09 37.5 0.4 3e-09 36.8 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAO84121.1 - 0.00026 20.6 0.1 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAO84121.1 - 0.00029 20.3 0.0 0.00042 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAO84121.1 - 0.0051 15.8 0.1 0.014 14.4 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_18 PF12847.2 GAO84121.1 - 0.011 16.2 0.0 0.044 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 GAO84121.1 - 0.022 13.7 0.1 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 GAO84121.1 - 0.05 13.3 1.4 0.31 10.8 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_12 PF08242.7 GAO84121.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 GAO84121.1 - 0.13 12.3 1.1 0.35 10.8 0.4 1.9 2 1 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 GAO84121.1 - 0.13 10.9 0.1 0.65 8.6 0.0 1.9 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Amino_oxidase PF01593.19 GAO84122.1 - 3.8e-56 191.0 2.7 2e-48 165.5 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DUF3574 PF12098.3 GAO84122.1 - 0.011 15.3 0.0 0.038 13.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) NAD_binding_8 PF13450.1 GAO84122.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glycos_transf_1 PF00534.15 GAO84123.1 - 2.3e-21 75.9 0.0 3.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO84123.1 - 3.1e-09 37.1 0.0 1.6e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAO84123.1 - 1.8e-05 24.8 0.0 5.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Endosulfine PF04667.12 GAO84125.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region p450 PF00067.17 GAO84126.1 - 0.057 11.9 0.4 0.17 10.3 0.2 1.6 1 1 0 1 1 1 0 Cytochrome P450 Jacalin PF01419.12 GAO84127.1 - 3.8e-06 26.8 2.2 7e-06 25.9 1.5 1.5 1 1 1 2 2 2 1 Jacalin-like lectin domain p450 PF00067.17 GAO84128.1 - 0.07 11.6 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Methyltransf_11 PF08241.7 GAO84129.1 - 3.3e-20 72.3 0.0 4.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO84129.1 - 2.2e-18 66.5 0.0 2.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84129.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84129.1 - 2e-17 63.1 0.0 2.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84129.1 - 2.3e-16 60.0 0.0 3.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO84129.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO84129.1 - 3.3e-10 40.0 0.0 6.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO84129.1 - 2.4e-08 33.4 0.0 5.7e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 GAO84129.1 - 1.1e-06 27.6 0.0 1.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 GAO84129.1 - 2.3e-05 24.4 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 GAO84129.1 - 2.3e-05 23.8 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 GAO84129.1 - 4.3e-05 22.7 0.0 6.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 GAO84129.1 - 6.6e-05 22.1 0.0 9.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 GAO84129.1 - 9.2e-05 21.6 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 GAO84129.1 - 0.00032 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO84129.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_24 PF13578.1 GAO84129.1 - 0.0019 19.0 0.0 0.0035 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 GAO84129.1 - 0.002 17.1 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 GAO84129.1 - 0.0029 16.9 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 GAO84129.1 - 0.0053 15.8 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Pox_MCEL PF03291.11 GAO84129.1 - 0.18 10.6 0.0 1.4 7.7 0.0 1.9 1 1 0 1 1 1 0 mRNA capping enzyme 3-dmu-9_3-mt PF06983.8 GAO84130.1 - 2.9e-52 175.8 0.5 2.9e-52 175.8 0.3 1.3 2 0 0 2 2 2 1 3-demethylubiquinone-9 3-methyltransferase Shikimate_dh_N PF08501.6 GAO84132.1 - 6.9e-21 74.0 0.0 1.7e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO84132.1 - 4.6e-12 46.1 0.0 7.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_II PF01220.14 GAO84133.1 - 3.6e-56 188.3 0.2 4.1e-56 188.1 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II SnoaL_4 PF13577.1 GAO84134.1 - 4.3e-06 26.6 0.1 5.9e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Shikimate_dh_N PF08501.6 GAO84135.1 - 2e-18 66.2 0.0 7.1e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO84135.1 - 4.2e-15 56.0 0.0 6.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SpoU_methylase PF00588.14 GAO84135.1 - 0.13 12.1 0.0 0.57 10.0 0.0 2.0 1 1 1 2 2 2 0 SpoU rRNA Methylase family AP_endonuc_2 PF01261.19 GAO84136.1 - 4.4e-27 94.7 0.0 5.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 GAO84137.1 - 6.3e-09 35.5 12.4 1.2e-08 34.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO84137.1 - 8.7e-05 21.5 0.0 0.00017 20.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 GAO84138.1 - 3.8e-21 75.7 0.0 6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 GAO84138.1 - 5e-20 71.3 0.0 1.3e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO84138.1 - 1.9e-10 41.0 0.0 5.4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.17 GAO84138.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase PAN_4 PF14295.1 GAO84139.1 - 2.2e-06 27.2 21.5 0.00021 20.8 1.2 3.7 4 0 0 4 4 4 2 PAN domain MANEC PF07502.9 GAO84139.1 - 0.0024 17.8 6.1 0.67 9.9 0.1 2.4 2 0 0 2 2 2 2 MANEC domain PAN_3 PF08277.7 GAO84139.1 - 1.4 8.6 11.2 3.7 7.2 4.0 2.8 2 1 0 2 2 2 0 PAN-like domain Aminotran_3 PF00202.16 GAO84140.1 - 8.5e-56 189.2 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III LysM PF01476.15 GAO84140.1 - 0.00065 19.5 2.9 0.00094 19.0 0.0 2.7 4 0 0 4 4 4 1 LysM domain Aldedh PF00171.17 GAO84141.1 - 1.8e-127 425.4 0.0 4e-127 424.3 0.0 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO84141.1 - 0.036 12.7 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Fungal_trans_2 PF11951.3 GAO84142.1 - 9e-34 116.6 1.2 1.2e-33 116.2 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84142.1 - 2.5e-05 24.0 8.4 4.9e-05 23.1 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAO84144.1 - 6.4e-26 91.2 0.1 1.1e-25 90.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84144.1 - 2.4e-21 76.6 0.0 2.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAO84144.1 - 2.4e-06 26.9 0.2 3.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 GAO84144.1 - 4.2e-05 23.2 0.1 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO84144.1 - 0.00011 22.2 0.1 0.00033 20.7 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 GAO84144.1 - 0.0018 18.2 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.21 GAO84144.1 - 0.0034 16.9 0.7 0.0094 15.5 0.5 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase QRPTase_C PF01729.14 GAO84144.1 - 0.0062 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1537 PF07005.6 GAO84144.1 - 0.011 15.4 0.2 0.54 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 2-Hacid_dh_C PF02826.14 GAO84144.1 - 0.025 13.7 0.0 0.068 12.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAO84144.1 - 0.031 13.1 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 GAO84144.1 - 0.065 12.2 0.1 0.088 11.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO84144.1 - 0.073 13.1 0.1 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAO84144.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.21 GAO84145.1 - 6.5e-12 45.1 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO84145.1 - 9.6e-05 22.1 0.1 0.00033 20.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO84145.1 - 0.072 13.9 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 GAO84146.1 - 9.9e-42 142.9 22.3 1.8e-41 142.0 15.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 GAO84146.1 - 2.3e-08 33.9 0.0 4.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.19 GAO84146.1 - 7.3e-08 31.4 13.6 7.3e-08 31.4 9.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Acetyltransf_7 PF13508.1 GAO84146.1 - 4.6e-07 29.9 0.0 8.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_2 PF13347.1 GAO84146.1 - 9.9e-07 27.4 1.7 0.049 12.0 6.8 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAO84146.1 - 0.0024 17.6 0.1 0.011 15.4 0.1 2.2 1 0 0 1 1 1 1 MFS_1 like family FR47 PF08445.5 GAO84146.1 - 0.0087 15.7 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Glyoxalase_2 PF12681.2 GAO84146.1 - 0.019 15.5 0.0 0.055 14.0 0.0 1.8 2 0 0 2 2 1 0 Glyoxalase-like domain ESSS PF10183.4 GAO84146.1 - 0.028 14.7 0.2 0.22 11.9 0.0 2.6 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acetyltransf_9 PF13527.1 GAO84146.1 - 0.042 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO84146.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 GAO84146.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_CG PF14542.1 GAO84146.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3353 PF11833.3 GAO84146.1 - 0.93 8.9 5.3 3.5 7.0 3.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Defensin_2 PF01097.13 GAO84147.1 - 5.9e-06 25.8 9.3 9.4e-06 25.2 6.4 1.3 1 0 0 1 1 1 1 Arthropod defensin Vma12 PF11712.3 GAO84147.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Toxin_38 PF14866.1 GAO84147.1 - 0.16 12.0 1.3 0.28 11.2 0.9 1.3 1 0 0 1 1 1 0 Potassium channel toxin Beta-lactamase PF00144.19 GAO84148.1 - 4.6e-42 144.2 0.0 7e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase TPR_12 PF13424.1 GAO84149.1 - 1.9e-15 56.5 15.8 7e-08 32.3 1.1 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 GAO84149.1 - 2.4e-05 24.3 29.5 0.032 14.5 0.3 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger TPR_1 PF00515.23 GAO84149.1 - 0.00021 20.7 6.2 0.36 10.5 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-C2H2 PF00096.21 GAO84149.1 - 0.00043 20.4 38.7 0.059 13.7 2.0 5.4 5 1 0 5 5 5 4 Zinc finger, C2H2 type TPR_10 PF13374.1 GAO84149.1 - 0.0016 18.3 11.5 0.053 13.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 GAO84149.1 - 0.0038 17.3 26.8 0.033 14.3 0.5 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.12 GAO84149.1 - 0.041 13.8 12.0 5.2 7.2 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84149.1 - 0.25 11.7 6.9 17 5.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAO84149.1 - 0.91 9.4 6.5 1.3 9.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.20 GAO84152.1 - 6.1e-16 58.7 0.0 8.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84152.1 - 2.1e-09 37.3 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO84152.1 - 9e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAO84152.1 - 9.4e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAO84152.1 - 0.0023 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAO84152.1 - 0.0055 15.6 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAO84152.1 - 0.027 14.7 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAO84152.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lipase_GDSL_2 PF13472.1 GAO84153.1 - 3.7e-18 66.2 0.0 7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO84153.1 - 4.6e-06 26.6 0.0 7.7e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SET PF00856.23 GAO84153.1 - 0.00046 20.5 0.0 0.013 15.8 0.0 2.3 1 1 0 1 1 1 1 SET domain AhpC-TSA_2 PF13911.1 GAO84154.1 - 1.1e-19 70.4 0.0 1.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAO84154.1 - 0.029 14.0 0.0 0.091 12.4 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family DUF2982 PF11201.3 GAO84154.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) LIP PF03583.9 GAO84155.1 - 6.5e-54 183.0 0.0 1.2e-53 182.2 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase DPBB_1 PF03330.13 GAO84156.1 - 1.1e-05 25.3 0.0 3.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 GAO84156.1 - 0.00052 19.7 0.0 0.0026 17.5 0.0 2.1 1 1 0 1 1 1 1 Pollen allergen Asp PF00026.18 GAO84158.1 - 1.1e-65 221.9 4.6 1.3e-65 221.7 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO84158.1 - 1.3e-08 34.9 0.0 8.1e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAO84158.1 - 4e-05 24.0 1.6 0.069 13.6 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease Ank_2 PF12796.2 GAO84159.1 - 1e-39 134.7 1.0 4.8e-12 46.0 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO84159.1 - 1.4e-26 92.3 1.0 6.2e-08 32.9 0.0 8.9 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 GAO84159.1 - 1.6e-25 87.6 17.1 3.1e-05 23.5 0.0 10.4 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.1 GAO84159.1 - 4.7e-25 87.0 1.8 3.4e-07 30.2 0.0 7.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Pkinase PF00069.20 GAO84159.1 - 3.7e-22 78.7 0.0 6.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 GAO84159.1 - 1.6e-20 71.1 2.9 0.00026 20.9 0.1 9.1 9 0 0 9 9 9 4 Ankyrin repeat Pkinase_Tyr PF07714.12 GAO84159.1 - 9.3e-16 57.6 0.0 1.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO84159.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 GAO84159.1 - 0.74 8.5 0.0 1.1 7.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HeLo PF14479.1 GAO84160.1 - 4.7e-23 82.0 0.5 8.6e-23 81.2 0.4 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 GAO84160.1 - 0.0015 17.6 0.0 0.0032 16.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAO84160.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DUF825 PF05695.7 GAO84160.1 - 0.026 11.9 0.6 0.037 11.4 0.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Glyco_hydro_16 PF00722.16 GAO84161.1 - 3.7e-42 143.7 7.3 3.7e-42 143.7 5.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 RAP1 PF07218.6 GAO84161.1 - 4.6 5.2 18.4 6 4.8 12.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kelch_4 PF13418.1 GAO84162.1 - 2.1e-09 36.9 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAO84162.1 - 5.5e-08 32.7 0.0 0.01 16.0 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO84162.1 - 6.4e-05 22.9 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 GAO84162.1 - 0.0018 17.8 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 GAO84162.1 - 0.0061 16.4 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 GAO84162.1 - 0.075 12.8 0.3 0.73 9.6 0.1 2.1 2 0 0 2 2 2 0 Kelch motif DUF3482 PF11981.3 GAO84163.1 - 0.055 12.6 3.1 0.083 12.1 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ISG65-75 PF11727.3 GAO84163.1 - 0.11 11.4 1.1 0.17 10.9 0.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Trp_syntA PF00290.15 GAO84164.1 - 1.1e-92 309.2 0.0 1.7e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 GAO84164.1 - 1.4e-45 155.8 0.2 2.4e-45 155.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KGG PF10685.4 GAO84165.1 - 1.2e-23 82.4 23.5 6.1e-10 38.7 0.1 4.1 4 0 0 4 4 4 4 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.12 GAO84165.1 - 0.16 12.2 3.8 0.48 10.7 0.7 2.0 1 1 1 2 2 2 0 Small hydrophilic plant seed protein MFS_1 PF07690.11 GAO84166.1 - 2.7e-35 121.7 28.9 2.7e-35 121.7 20.0 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily GATase PF00117.23 GAO84167.1 - 0.0031 16.9 0.1 0.0047 16.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NACHT PF05729.7 GAO84169.1 - 4.2e-11 42.7 0.1 1.3e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAO84169.1 - 7.3e-05 22.9 0.0 0.028 14.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAO84169.1 - 0.014 14.8 0.0 0.053 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 GAO84169.1 - 0.028 14.4 0.1 0.028 14.4 0.1 3.8 4 1 0 4 4 4 0 AAA ATPase domain cobW PF02492.14 GAO84169.1 - 0.11 11.8 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAO84169.1 - 0.14 11.5 0.1 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Glyco_hydro_39 PF01229.12 GAO84170.1 - 0.0007 18.1 0.0 0.00099 17.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 JmjC PF02373.17 GAO84171.1 - 4.2e-08 33.4 0.0 0.0029 17.8 0.0 2.4 1 1 1 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.7 GAO84171.1 - 0.002 17.4 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.9 GAO84171.1 - 0.089 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ARD/ARD' family F-box PF00646.28 GAO84172.1 - 0.0071 15.9 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain NUDIX PF00293.23 GAO84173.1 - 3.2e-12 46.2 0.0 6.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 GAO84173.1 - 2.4e-11 43.9 0.0 1.4e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAO84173.1 - 0.0015 19.3 0.4 0.0043 17.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAO84173.1 - 0.0043 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAO84173.1 - 0.0061 16.7 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO84173.1 - 0.0087 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAO84173.1 - 0.013 15.7 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 GAO84173.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 GAO84173.1 - 0.039 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAO84173.1 - 0.049 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NUDIX_4 PF14815.1 GAO84173.1 - 0.077 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain AAA_33 PF13671.1 GAO84173.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAO84173.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ank_2 PF12796.2 GAO84174.1 - 3e-171 556.3 86.9 1.2e-20 73.6 0.5 8.8 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO84174.1 - 7e-122 395.9 22.7 3.8e-10 40.0 0.0 13.1 3 3 11 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.25 GAO84174.1 - 1.7e-108 349.3 67.7 2.8e-06 26.8 0.0 19.3 19 0 0 19 19 19 18 Ankyrin repeat Ank_3 PF13606.1 GAO84174.1 - 2.2e-86 275.0 28.8 0.001 19.1 0.0 19.3 20 0 0 20 20 19 18 Ankyrin repeat Ank_5 PF13857.1 GAO84174.1 - 8e-80 261.0 57.6 0.00064 19.8 0.0 18.8 11 5 7 18 18 18 18 Ankyrin repeats (many copies) FA PF08736.6 GAO84174.1 - 3.7e-08 33.0 22.5 2.7 7.8 0.0 11.9 15 0 0 15 15 15 3 FERM adjacent (FA) AAA_22 PF13401.1 GAO84174.1 - 1.4e-06 28.4 0.1 6.7e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAO84174.1 - 1.7e-06 27.7 0.0 4.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SnoaL_2 PF12680.2 GAO84174.1 - 0.027 14.8 19.7 19 5.7 0.6 8.0 3 2 3 7 7 7 0 SnoaL-like domain NB-ARC PF00931.17 GAO84174.1 - 0.033 13.0 0.1 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_1 PF00561.15 GAO84174.1 - 0.28 10.7 6.2 3.1 7.2 0.0 3.9 5 0 0 5 5 5 0 alpha/beta hydrolase fold DUF3723 PF12520.3 GAO84177.1 - 2.1e-43 148.6 0.2 2.7e-43 148.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Methyltransf_23 PF13489.1 GAO84178.1 - 2.4e-10 40.3 0.0 3.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84178.1 - 0.0031 17.9 0.0 0.044 14.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO84178.1 - 0.098 13.1 0.0 0.27 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAO84178.1 - 0.11 12.9 0.0 3.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain DUF4246 PF14033.1 GAO84179.1 - 7.8e-168 559.1 2.3 9.3e-168 558.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF2514 PF10721.4 GAO84180.1 - 0.058 13.1 0.7 0.11 12.1 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) OPT PF03169.10 GAO84181.1 - 1.1e-137 460.0 44.0 1.3e-137 459.9 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SnoaL_2 PF12680.2 GAO84182.1 - 6e-14 52.2 2.0 7.5e-14 51.9 1.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 GAO84182.1 - 2.3e-09 37.2 0.5 2.5e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 GAO84182.1 - 5.6e-07 29.5 0.6 6.8e-07 29.3 0.4 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain NTF2 PF02136.15 GAO84182.1 - 1.3e-06 28.7 0.2 1.7e-06 28.4 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.1 GAO84182.1 - 3.1e-06 27.2 0.2 3.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAO84182.1 - 5.2e-05 23.4 0.6 7.7e-05 22.8 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 GAO84182.1 - 0.00027 20.5 1.2 0.00033 20.2 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase EF-hand_1 PF00036.27 GAO84182.1 - 0.43 10.0 2.0 1.1 8.7 0.3 2.3 2 0 0 2 2 2 0 EF hand Fungal_trans PF04082.13 GAO84183.1 - 4.4e-23 81.4 0.4 7e-23 80.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84183.1 - 2e-08 34.0 9.8 4e-08 33.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAO84184.1 - 2.1e-21 75.9 0.0 3e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Macro_2 PF14519.1 GAO84184.1 - 3.3e-06 26.4 0.0 4.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 GAO84184.1 - 0.031 14.1 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 Macro domain ABC_membrane PF00664.18 GAO84185.1 - 1.3e-84 283.8 33.3 5.3e-44 150.6 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO84185.1 - 1e-68 229.8 0.0 2.3e-33 115.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO84185.1 - 1.7e-13 51.2 0.0 0.006 16.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAO84185.1 - 1.1e-10 41.1 6.3 0.0011 18.2 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 GAO84185.1 - 4.3e-09 35.4 0.8 0.0034 16.0 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 GAO84185.1 - 4.5e-09 36.5 5.7 2.8e-05 24.1 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAO84185.1 - 9.2e-09 34.7 1.4 0.00072 19.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAO84185.1 - 1.2e-08 34.2 0.0 0.001 18.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAO84185.1 - 2.8e-07 31.4 0.0 0.0083 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO84185.1 - 2.3e-06 27.7 1.0 0.32 11.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO84185.1 - 9.2e-06 25.1 0.2 0.12 11.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 GAO84185.1 - 0.0001 22.5 3.7 0.027 14.6 0.2 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAO84185.1 - 0.0001 22.0 0.1 0.46 10.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAO84185.1 - 0.00015 21.6 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO84185.1 - 0.00028 21.2 0.0 0.69 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAO84185.1 - 0.00029 20.7 0.0 0.52 10.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 GAO84185.1 - 0.00057 19.8 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAO84185.1 - 0.00065 19.6 0.0 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 GAO84185.1 - 0.0041 16.8 0.2 0.79 9.4 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAO84185.1 - 0.0054 16.1 2.7 1.2 8.5 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain RNA_helicase PF00910.17 GAO84185.1 - 0.0076 16.4 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 GAO84185.1 - 0.012 15.4 0.5 0.094 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 GAO84185.1 - 0.033 13.7 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 GAO84185.1 - 0.042 12.5 0.0 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 GAO84185.1 - 0.11 11.1 0.0 8.2 4.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.1 GAO84185.1 - 0.18 12.0 5.9 3.5 7.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Sec7_N PF12783.2 GAO84185.1 - 0.32 10.4 1.0 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SbcCD_C PF13558.1 GAO84185.1 - 0.51 10.2 14.4 0.72 9.8 0.1 4.2 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit Dioxygenase_C PF00775.16 GAO84187.1 - 9.8e-13 47.7 0.1 2.1e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Sugar_tr PF00083.19 GAO84188.1 - 4.2e-123 411.2 30.1 4.8e-123 411.0 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84188.1 - 2.5e-20 72.4 39.4 2.5e-18 65.9 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO84188.1 - 1.7e-06 26.6 25.2 0.00011 20.7 5.2 3.3 3 0 0 3 3 3 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 GAO84188.1 - 0.028 14.4 4.9 0.043 13.9 2.5 2.0 2 0 0 2 2 2 0 Phage holin family 2 MFS_1_like PF12832.2 GAO84188.1 - 0.21 11.3 0.1 0.21 11.3 0.1 4.0 4 1 0 4 4 4 0 MFS_1 like family Retrotrans_gag PF03732.12 GAO84189.1 - 5.5e-05 23.1 0.6 0.00013 21.9 0.4 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein CVNH PF08881.5 GAO84189.1 - 0.001 19.2 0.1 0.0029 17.7 0.1 1.7 1 1 0 1 1 1 1 CVNH domain DHC_N1 PF08385.7 GAO84189.1 - 0.049 12.0 0.1 0.066 11.5 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 CVNH PF08881.5 GAO84190.1 - 1.3e-33 115.3 0.1 1.4e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.19 GAO84191.1 - 2.7e-32 112.2 23.6 3.8e-32 111.7 16.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase FAD_binding_3 PF01494.14 GAO84192.1 - 5.4e-71 239.5 0.1 8.4e-70 235.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 GAO84192.1 - 9.7e-44 149.5 21.2 9.7e-44 149.5 14.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phe_hydrox_dim PF07976.7 GAO84192.1 - 1e-24 87.0 0.0 1.9e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Sugar_tr PF00083.19 GAO84192.1 - 7.2e-18 64.3 9.2 1.1e-17 63.8 6.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAO84192.1 - 0.00022 19.5 0.9 0.00035 18.8 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SE PF08491.5 GAO84192.1 - 0.0082 14.9 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 Squalene epoxidase MFS_3 PF05977.8 GAO84192.1 - 0.094 10.8 0.5 0.2 9.7 0.4 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Pyr_redox_2 PF07992.9 GAO84192.1 - 0.13 12.1 0.0 0.96 9.2 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO84192.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAO84194.1 - 1.2e-20 74.4 0.0 5.6e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO84194.1 - 5.4e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAO84194.1 - 5.1e-10 38.1 2.0 1e-09 37.1 0.2 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO84194.1 - 1.7e-07 30.4 0.4 9e-05 21.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO84194.1 - 2.6e-07 30.7 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO84194.1 - 4.3e-05 22.5 0.0 0.019 13.9 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO84194.1 - 0.00067 19.4 2.0 0.013 15.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAO84194.1 - 0.028 13.3 0.1 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 GAO84194.1 - 0.15 10.9 0.0 10 4.8 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.13 GAO84195.1 - 8.5e-06 24.8 2.0 6.6e-05 21.9 1.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAO84196.1 - 2.5e-21 76.3 0.1 6.8e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84196.1 - 9.6e-10 38.6 0.3 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84196.1 - 4.1e-08 33.0 0.0 7.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO84196.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_28 PF00295.12 GAO84197.1 - 1.6e-48 165.3 10.2 2.9e-48 164.5 7.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 MPC PF03650.8 GAO84198.1 - 1.2e-43 147.8 0.2 1.6e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 GAO84199.1 - 6.8e-15 54.5 0.0 8.5e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.13 GAO84200.1 - 8.5e-51 172.5 0.0 1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sel1 PF08238.7 GAO84201.1 - 4.9e-44 147.7 31.6 1.4e-08 35.0 0.4 7.9 7 0 0 7 7 7 7 Sel1 repeat CBP4 PF07960.6 GAO84202.1 - 9e-38 128.7 1.7 1.1e-37 128.4 1.2 1.1 1 0 0 1 1 1 1 CBP4 AAA_11 PF13086.1 GAO84202.1 - 0.076 12.5 0.8 0.084 12.4 0.5 1.1 1 0 0 1 1 1 0 AAA domain Endonuc-dimeris PF09124.5 GAO84202.1 - 0.082 12.5 4.7 4.8 6.8 0.1 2.9 2 1 1 3 3 3 0 T4 recombination endonuclease VII, dimerisation DUF4303 PF14136.1 GAO84202.1 - 3.9 7.0 6.3 10 5.7 4.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) Synaptobrevin PF00957.16 GAO84203.1 - 2e-31 107.4 0.2 2.3e-31 107.2 0.2 1.0 1 0 0 1 1 1 1 Synaptobrevin Cas_CXXC_CXXC PF09706.5 GAO84203.1 - 0.2 11.8 1.4 0.44 10.7 1.0 1.7 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) PRT_C PF08372.5 GAO84203.1 - 0.29 10.6 2.4 0.67 9.4 1.6 1.5 1 1 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal UPF0239 PF06783.6 GAO84203.1 - 0.29 11.0 0.1 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Prominin PF05478.6 GAO84203.1 - 0.37 8.2 2.4 0.6 7.5 1.7 1.3 1 1 0 1 1 1 0 Prominin DUF619 PF04768.8 GAO84204.1 - 1.1e-56 190.9 0.1 2e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Rad21_Rec8_N PF04825.8 GAO84204.1 - 3.9e-31 107.2 0.0 7.8e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Semialdhyde_dh PF01118.19 GAO84204.1 - 2e-29 102.3 0.0 5.4e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 GAO84204.1 - 8.9e-24 84.3 0.0 1.9e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 GAO84204.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3237 PF11578.3 GAO84205.1 - 6.4e-37 126.1 0.0 9.6e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 GAO84205.1 - 1.5e-07 31.0 2.2 0.008 15.9 0.1 2.5 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 GAO84205.1 - 0.024 14.6 7.6 0.61 10.1 5.1 2.7 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein Tmemb_55A PF09788.4 GAO84205.1 - 0.058 12.5 6.5 0.34 9.9 0.9 2.3 2 0 0 2 2 2 0 Transmembrane protein 55A zf-C2H2_2 PF12756.2 GAO84205.1 - 0.14 12.3 6.5 4 7.6 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF605 PF04652.11 GAO84205.1 - 0.5 9.7 8.0 0.64 9.3 5.5 1.1 1 0 0 1 1 1 0 Vta1 like ICL PF00463.16 GAO84206.1 - 1.1e-193 644.2 0.0 1.2e-193 644.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAO84206.1 - 9.7e-10 38.0 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 GAO84206.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Fungal_trans_2 PF11951.3 GAO84207.1 - 3.3e-59 200.3 1.2 4.8e-59 199.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain VGLL4 PF15245.1 GAO84207.1 - 0.0088 15.8 0.3 0.02 14.7 0.2 1.6 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 Zn_clus PF00172.13 GAO84207.1 - 0.032 14.1 1.0 0.061 13.2 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.7 GAO84208.1 - 4.5e-11 42.5 0.0 5.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 GAO84208.1 - 5.8e-09 35.2 0.0 7.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 GAO84208.1 - 7e-05 22.2 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 GAO84208.1 - 0.025 14.1 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin Pkinase PF00069.20 GAO84209.1 - 4.3e-56 189.9 0.1 3e-55 187.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84209.1 - 1.1e-28 100.0 0.1 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAO84209.1 - 3.5e-06 27.4 0.0 9.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 GAO84209.1 - 0.00029 20.6 0.2 0.11 12.2 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO84209.1 - 0.00036 19.5 0.1 0.0028 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAO84209.1 - 0.048 12.7 1.3 0.13 11.3 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.6 GAO84210.1 - 3.6e-13 49.6 0.0 1.1e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) OSCP PF00213.13 GAO84210.1 - 0.048 13.5 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit FAD_binding_8 PF08022.7 GAO84211.1 - 8.7e-21 73.7 0.0 1.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAO84211.1 - 9.6e-19 67.8 0.0 2e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAO84211.1 - 2.8e-17 62.9 12.2 6.7e-17 61.7 8.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAO84211.1 - 0.00054 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ctr PF04145.10 GAO84212.1 - 7.6e-37 126.5 0.5 9.3e-37 126.2 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family CoA_binding_3 PF13727.1 GAO84212.1 - 1.3 8.7 3.9 3.4 7.4 0.0 2.1 1 1 1 2 2 2 0 CoA-binding domain COX7a PF02238.10 GAO84212.1 - 1.5 8.6 3.8 11 5.8 0.3 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa AF-4 PF05110.8 GAO84213.1 - 2.3 5.9 5.7 2.6 5.7 3.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AATase PF07247.7 GAO84214.1 - 1.2e-30 106.5 0.0 1.8e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAO84214.1 - 1.6e-07 30.4 0.0 9.8e-05 21.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Abhydrolase_2 PF02230.11 GAO84215.1 - 8.1e-53 179.0 0.0 1e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAO84215.1 - 1.6e-10 40.9 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO84215.1 - 3e-06 27.3 0.0 0.01 15.7 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO84215.1 - 0.00021 20.5 0.1 0.0007 18.8 0.0 1.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 GAO84215.1 - 0.0016 17.8 0.0 0.0039 16.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 GAO84215.1 - 0.0088 15.3 0.0 0.71 9.2 0.0 2.2 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_3 PF07859.8 GAO84215.1 - 0.0099 15.4 0.0 0.041 13.4 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.9 GAO84215.1 - 0.087 12.0 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.20 GAO84215.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 GAO84215.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.8 GAO84216.1 - 6.1e-30 104.2 0.0 8.6e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAO84216.1 - 0.00088 19.2 0.0 0.12 12.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84216.1 - 0.006 16.3 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAO84216.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAO84216.1 - 0.065 12.8 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 GAO84216.1 - 0.095 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Epimerase PF01370.16 GAO84217.1 - 5.9e-22 78.2 0.0 3.7e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO84217.1 - 3.1e-16 59.7 2.1 6.6e-14 52.1 1.2 3.1 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO84217.1 - 1.2e-08 34.1 0.0 2.4e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 GAO84217.1 - 7.8e-06 25.6 0.1 1.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAO84217.1 - 4e-05 22.4 0.0 7.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO84217.1 - 0.00057 18.8 0.1 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAO84217.1 - 0.00094 18.1 0.0 0.32 9.8 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAO84217.1 - 0.0094 15.9 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding NAC PF01849.13 GAO84218.1 - 9.9e-16 57.0 3.0 8.7e-13 47.5 0.7 2.5 2 0 0 2 2 2 2 NAC domain PI31_Prot_N PF11566.3 GAO84218.1 - 0.02 14.5 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal His_Phos_2 PF00328.17 GAO84219.1 - 9.9e-35 120.4 0.0 1.5e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 GAO84220.1 - 3.8e-31 108.0 29.8 1.2e-30 106.4 21.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.4 GAO84220.1 - 1.7 8.9 7.2 2.3 8.5 0.0 3.7 3 1 2 5 5 5 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit FMN_dh PF01070.13 GAO84221.1 - 3.1e-122 407.8 0.0 3.6e-122 407.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 GAO84221.1 - 1.8e-05 24.0 1.1 3.1e-05 23.2 0.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 GAO84221.1 - 4.7e-05 22.5 0.3 0.11 11.6 0.2 2.7 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 GAO84221.1 - 0.0016 17.4 0.5 0.0025 16.7 0.1 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAO84221.1 - 0.0045 16.2 0.2 1.2 8.3 0.0 2.6 1 1 1 2 2 2 2 Histidine biosynthesis protein IMPDH PF00478.20 GAO84221.1 - 0.024 13.5 0.4 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DRTGG PF07085.7 GAO84221.1 - 0.14 11.8 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 DRTGG domain Lipase_3 PF01764.20 GAO84222.1 - 3.6e-14 52.5 0.0 7.5e-13 48.3 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 GAO84222.1 - 0.0071 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84222.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO84222.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Tektin PF03148.9 GAO84223.1 - 0.0029 16.2 1.6 0.0031 16.1 1.1 1.0 1 0 0 1 1 1 1 Tektin family Phasin PF05597.6 GAO84223.1 - 0.0035 17.1 2.3 0.0044 16.7 1.6 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) MerR-DNA-bind PF09278.6 GAO84223.1 - 0.0069 16.7 6.7 0.11 12.9 0.2 2.1 1 1 1 2 2 2 2 MerR, DNA binding DUF4446 PF14584.1 GAO84223.1 - 0.0075 16.1 0.9 0.0092 15.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Pol_alpha_B_N PF08418.5 GAO84223.1 - 0.012 15.1 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal KorB PF08535.5 GAO84223.1 - 0.019 15.1 0.4 0.027 14.6 0.2 1.4 1 1 0 1 1 1 0 KorB domain DUF4140 PF13600.1 GAO84223.1 - 0.024 15.0 2.0 0.032 14.6 1.4 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.5 GAO84223.1 - 0.026 14.5 4.2 2.2 8.4 1.4 2.3 1 1 1 2 2 2 0 Osmosensory transporter coiled coil ApoL PF05461.6 GAO84223.1 - 0.029 13.6 2.2 0.035 13.3 1.5 1.0 1 0 0 1 1 1 0 Apolipoprotein L Cortex-I_coil PF09304.5 GAO84223.1 - 0.031 14.2 3.8 0.047 13.7 2.7 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Ax_dynein_light PF10211.4 GAO84223.1 - 0.054 13.3 3.5 0.062 13.1 2.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Frigida PF07899.6 GAO84223.1 - 0.12 11.0 2.2 0.14 10.9 1.5 1.0 1 0 0 1 1 1 0 Frigida-like protein DivIC PF04977.10 GAO84223.1 - 0.8 9.2 5.2 2.6 7.6 3.6 1.8 1 1 0 1 1 1 0 Septum formation initiator DnaG_DnaB_bind PF08278.6 GAO84223.1 - 1.1 9.4 6.0 0.7 10.1 0.4 2.0 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding Vpu PF00558.14 GAO84223.1 - 2.1 7.9 4.9 1.6 8.3 2.0 1.8 1 1 1 2 2 2 0 Vpu protein DUF3735 PF12537.3 GAO84223.1 - 2.4 8.2 4.2 6.5 6.8 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3735) SMC_N PF02463.14 GAO84224.1 - 3.1e-22 78.9 0.2 1.7e-21 76.5 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAO84224.1 - 4.7e-13 49.9 23.0 4.7e-13 49.9 15.9 6.1 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 GAO84224.1 - 6.8e-06 26.2 4.0 0.0012 18.9 0.0 3.3 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 GAO84224.1 - 0.0023 17.4 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 GAO84224.1 - 0.0077 14.7 71.1 0.041 12.3 10.9 4.8 3 2 2 5 5 5 3 AAA domain Reo_sigmaC PF04582.7 GAO84224.1 - 0.0081 15.3 3.5 1.5 7.9 0.2 3.9 2 1 1 3 3 3 1 Reovirus sigma C capsid protein ABC_tran PF00005.22 GAO84224.1 - 0.068 13.4 0.0 0.068 13.4 0.0 4.9 3 2 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 GAO84224.1 - 0.075 12.4 0.0 0.075 12.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 GAO84224.1 - 0.18 11.5 0.0 0.52 10.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAO84224.1 - 4.4 7.4 6.4 1.7 8.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain zf-C2H2 PF00096.21 GAO84225.1 - 4.3e-07 29.8 15.5 0.0029 17.8 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO84225.1 - 2.1e-05 24.5 0.9 2.1e-05 24.5 0.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 GAO84225.1 - 0.2 11.9 4.1 0.39 10.9 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 GAO84225.1 - 0.23 11.4 1.9 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 GAO84225.1 - 0.38 10.5 11.5 0.78 9.5 2.1 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 GAO84225.1 - 0.71 10.3 18.4 0.091 13.1 1.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger BTB PF00651.26 GAO84226.1 - 8.4e-26 90.1 0.0 6.6e-13 48.6 0.3 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 GAO84226.1 - 4.7e-09 36.4 0.0 9.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84226.1 - 4e-08 32.6 0.1 8.1e-06 25.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 GAO84226.1 - 3.5e-07 30.2 0.1 9.8e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO84226.1 - 4e-07 30.3 0.0 9.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO84226.1 - 0.0012 18.9 0.1 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 GAO84227.1 - 1.9e-58 197.6 0.8 2.4e-58 197.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84227.1 - 5.8e-37 127.1 0.0 9.4e-26 90.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO84227.1 - 0.0035 16.3 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF607 PF04678.8 GAO84227.1 - 0.018 15.0 1.2 0.034 14.0 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 APH PF01636.18 GAO84227.1 - 0.019 14.7 0.5 0.096 12.4 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Toxin_52 PF15605.1 GAO84227.1 - 0.088 12.7 1.2 0.2 11.5 0.8 1.5 1 0 0 1 1 1 0 Putative toxin 52 DUF342 PF03961.8 GAO84227.1 - 0.61 8.4 5.3 0.96 7.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 GAO84227.1 - 2.2 7.2 11.2 4 6.4 7.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Wbp11 PF09429.5 GAO84228.1 - 6.9e-23 80.4 17.6 6.9e-23 80.4 12.2 2.5 2 1 0 2 2 2 1 WW domain binding protein 11 Syntaxin PF00804.20 GAO84229.1 - 0.02 15.0 3.0 2.4 8.3 0.1 2.5 1 1 1 2 2 2 0 Syntaxin HTH_16 PF12645.2 GAO84229.1 - 0.081 12.8 0.2 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DEAD PF00270.24 GAO84230.1 - 1.9e-35 121.8 0.0 3.3e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO84230.1 - 4.2e-24 84.1 0.0 5.5e-23 80.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO84230.1 - 2.4e-06 27.4 0.1 7.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAO84230.1 - 0.0025 16.9 0.0 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 GAO84230.1 - 0.0092 15.3 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ApbA PF02558.11 GAO84231.1 - 4.2e-22 78.2 0.0 6.7e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAO84231.1 - 3.9e-21 75.3 0.0 6.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 GAO84232.1 - 2e-21 75.9 2.3 2.8e-21 75.4 1.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.1 GAO84232.1 - 0.0025 16.4 0.0 0.0033 16.0 0.0 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal NAD_binding_10 PF13460.1 GAO84233.1 - 6.4e-06 26.2 0.0 1e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO84233.1 - 1.2e-05 24.3 0.0 0.095 11.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 GAO84233.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO84233.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AdoMet_MTase PF07757.8 GAO84234.1 - 2.5e-34 117.7 0.2 1.1e-33 115.7 0.1 1.9 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PDT PF00800.13 GAO84234.1 - 0.026 14.0 0.2 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydratase Melibiase PF02065.13 GAO84235.1 - 8.3e-40 136.6 0.0 5.6e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Melibiase Corona_6B_7B PF03262.8 GAO84235.1 - 0.051 12.8 0.1 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Coronavirus 6B/7B protein Glyco_hydro_97 PF10566.4 GAO84235.1 - 0.061 12.4 0.3 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Glycoside hydrolase 97 CorA PF01544.13 GAO84236.1 - 1.1e-08 34.4 0.1 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RHH_3 PF12651.2 GAO84236.1 - 0.58 9.9 2.4 0.82 9.4 0.2 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain HTH_Tnp_Tc5 PF03221.11 GAO84237.1 - 1.7e-11 43.7 0.2 3.4e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAO84237.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 GAO84237.1 - 0.012 14.9 0.5 0.086 12.2 0.0 2.5 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 GAO84237.1 - 0.015 15.2 1.0 0.19 11.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_8 PF02954.14 GAO84237.1 - 0.022 14.2 0.3 0.55 9.8 0.0 3.0 3 1 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.1 GAO84237.1 - 0.03 13.9 0.6 0.99 9.1 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 GAO84237.1 - 0.064 13.2 0.1 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Transposase HTH_38 PF13936.1 GAO84237.1 - 0.11 12.0 0.8 15 5.2 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain WH1 PF00568.18 GAO84238.1 - 9.5e-28 96.1 0.0 1.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 GAO84238.1 - 0.021 14.4 4.0 0.099 12.2 2.8 2.1 1 1 0 1 1 1 0 WH2 motif ERCC4 PF02732.10 GAO84239.1 - 7.1e-26 90.6 0.0 1.7e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 GAO84239.1 - 0.00048 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain eIF-1a PF01176.14 GAO84241.1 - 4.4e-29 99.6 0.2 6.3e-29 99.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 GAO84242.1 - 6.6e-11 41.9 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAO84242.1 - 2.2e-07 30.8 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 GAO84242.1 - 0.00025 21.0 0.0 0.00069 19.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Aminotran_1_2 PF00155.16 GAO84243.1 - 2.9e-78 263.3 0.0 3.3e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO84243.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 2 0 0 2 2 2 0 Beta-eliminating lyase Abhydrolase_3 PF07859.8 GAO84244.1 - 7.6e-58 195.5 0.1 9.6e-58 195.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84244.1 - 3.4e-06 26.4 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 GAO84244.1 - 0.00096 17.9 0.1 0.0029 16.3 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAO84244.1 - 0.0039 17.1 1.2 0.0063 16.4 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAO84244.1 - 0.05 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 GAO84244.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lyase_1 PF00206.15 GAO84245.1 - 2.3e-115 385.0 0.0 3.3e-115 384.5 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 GAO84245.1 - 1.4e-22 79.4 0.0 3.9e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Calpain_inhib PF00748.14 GAO84245.1 - 0.058 13.7 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Calpain inhibitor Acetyltransf_7 PF13508.1 GAO84246.1 - 3.9e-10 39.7 0.3 5.4e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO84246.1 - 3e-09 36.7 0.1 4.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO84246.1 - 0.0072 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO84246.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.15 GAO84247.1 - 6e-31 106.1 0.4 6e-31 106.1 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.21 GAO84248.1 - 3.4e-47 159.3 0.0 3.9e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO84248.1 - 0.00018 21.2 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAO84248.1 - 0.011 15.3 0.1 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 GAO84248.1 - 0.017 15.0 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 GAO84249.1 - 4.2e-11 42.2 17.6 0.00015 21.5 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 GAO84249.1 - 0.0014 18.6 6.0 0.0034 17.3 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO84249.1 - 0.0027 17.4 6.1 0.0071 16.1 4.2 1.7 1 0 0 1 1 1 1 Ring finger domain RWD PF05773.17 GAO84249.1 - 0.0058 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.20 GAO84249.1 - 0.012 15.2 3.1 0.035 13.7 2.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRI12 PF06609.8 GAO84250.1 - 2.3e-37 128.5 27.6 2.9e-37 128.1 19.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAO84250.1 - 5.9e-19 68.0 56.8 7.6e-19 67.6 35.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84250.1 - 2.7e-08 32.8 45.1 2.8e-07 29.5 10.9 3.4 2 1 2 4 4 4 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 GAO84250.1 - 0.00054 19.5 4.5 0.00054 19.5 3.1 2.5 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus 4HBT PF03061.17 GAO84251.1 - 1.6e-08 34.5 0.1 2.7e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.24 GAO84252.1 - 4.4e-55 186.6 0.0 5.4e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO84252.1 - 1.7e-16 60.5 0.2 9.1e-16 58.1 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAO84252.1 - 8.2e-11 41.1 0.0 3.1e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAO84252.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain ARPC4 PF05856.7 GAO84253.1 - 4.9e-75 250.6 4.1 5.7e-75 250.3 2.8 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 GAO84254.1 - 0.18 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TYW3 PF02676.9 GAO84255.1 - 2e-76 255.6 0.0 2.5e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 GAO84256.1 - 4.2e-35 121.0 0.3 7.4e-35 120.2 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF2461 PF09365.5 GAO84257.1 - 1.7e-32 112.5 0.0 1.9e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Zn_clus PF00172.13 GAO84258.1 - 6e-09 35.6 7.4 8.5e-09 35.1 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4246 PF14033.1 GAO84261.1 - 4e-138 461.1 0.0 7.1e-138 460.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) Pkinase PF00069.20 GAO84263.1 - 1.8e-69 233.8 0.0 2.9e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84263.1 - 6e-36 123.8 0.0 7.2e-34 117.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO84263.1 - 0.00075 19.2 0.1 0.02 14.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO84263.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAO84263.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 GAO84263.1 - 0.012 15.1 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1348 PF07080.6 GAO84264.1 - 1.3e-45 154.7 2.3 1.5e-45 154.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 GAO84264.1 - 5.1e-06 26.6 0.3 7.2e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 GAO84264.1 - 6.6e-06 26.4 0.8 8.9e-06 26.0 0.5 1.4 1 1 0 1 1 1 1 SnoaL-like domain Redoxin PF08534.5 GAO84265.1 - 5.3e-37 126.6 0.0 5.9e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAO84265.1 - 1.4e-15 57.0 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family POP1 PF06978.6 GAO84266.1 - 2.7e-66 222.7 18.1 2.7e-66 222.7 12.5 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 GAO84266.1 - 9.9e-34 115.0 1.7 2.4e-33 113.8 0.6 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF1690 PF07956.6 GAO84267.1 - 4.3e-31 107.8 4.5 6.7e-16 58.5 0.1 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) DUF848 PF05852.6 GAO84267.1 - 0.014 15.2 5.6 0.081 12.7 0.3 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Laminin_I PF06008.9 GAO84267.1 - 0.019 14.2 3.9 0.11 11.7 1.2 2.1 2 0 0 2 2 2 0 Laminin Domain I Terminase_2 PF03592.11 GAO84267.1 - 0.02 15.1 0.7 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Terminase small subunit Apolipoprotein PF01442.13 GAO84267.1 - 0.063 12.7 12.6 0.92 8.9 2.8 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4148 PF13663.1 GAO84267.1 - 0.067 13.0 0.4 0.067 13.0 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) DUF3835 PF12927.2 GAO84267.1 - 0.28 12.1 2.6 14 6.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) DUF4071 PF13281.1 GAO84267.1 - 0.48 9.2 3.5 0.3 9.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) Phasin PF05597.6 GAO84267.1 - 0.5 10.1 6.6 0.39 10.4 0.3 2.4 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 GAO84267.1 - 1.1 9.6 8.1 0.91 9.9 1.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) cwf21 PF08312.7 GAO84267.1 - 2.1 8.2 17.0 2 8.3 3.1 3.3 2 1 1 3 3 3 0 cwf21 domain Herpes_UL25 PF01499.11 GAO84267.1 - 2.8 6.1 9.1 0.81 7.9 4.0 1.6 1 1 1 2 2 2 0 Herpesvirus UL25 family Hexokinase_2 PF03727.11 GAO84268.1 - 3.2e-71 239.4 0.0 4.2e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAO84268.1 - 4.2e-64 215.6 0.0 6.6e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HTH_28 PF13518.1 GAO84268.1 - 0.12 12.3 0.1 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.11 GAO84269.1 - 1.8e-43 148.6 45.9 1.8e-43 148.6 31.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO84269.1 - 2.6e-12 45.7 26.2 3.7e-12 45.2 18.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mpv17_PMP22 PF04117.7 GAO84270.1 - 5.9e-15 54.6 0.0 1.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family p450 PF00067.17 GAO84271.1 - 1.1e-69 235.1 0.0 1.5e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 GAO84271.1 - 0.12 12.2 0.8 0.21 11.3 0.6 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2HC5 PF06221.8 GAO84272.1 - 3.3e-24 84.3 5.3 5.1e-24 83.7 3.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 GAO84273.1 - 7.1e-11 41.2 2.1 8.7e-11 40.9 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 GAO84273.1 - 0.036 13.7 0.9 0.069 12.8 0.6 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Tmemb_55A PF09788.4 GAO84273.1 - 0.09 11.8 1.4 0.17 10.9 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A SKIP_SNW PF02731.10 GAO84273.1 - 1.9 7.9 5.5 4 6.8 0.1 2.4 2 0 0 2 2 2 0 SKIP/SNW domain Acetyltransf_1 PF00583.19 GAO84274.1 - 0.00029 20.8 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Ferric_reduct PF01794.14 GAO84275.1 - 1.3e-20 73.7 14.3 1.3e-20 73.7 9.9 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO84275.1 - 2e-20 73.2 0.0 3.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO84275.1 - 4.4e-13 49.0 0.0 8.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAO84275.1 - 8.6e-06 26.2 0.0 0.0015 19.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 GAO84276.1 - 2.2e-17 63.5 0.4 2.4e-15 56.9 0.3 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAO84276.1 - 0.11 12.4 0.1 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 Peptidase_A22B PF04258.8 GAO84277.1 - 2.9e-57 194.3 0.0 3.2e-56 190.9 0.0 2.0 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 GAO84277.1 - 0.00052 19.2 5.1 0.00052 19.2 3.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Amdo_NSP PF12475.3 GAO84277.1 - 0.025 14.4 0.0 0.081 12.8 0.0 1.9 1 1 0 1 1 1 0 Amdovirus non-structural protein Pro_isomerase PF00160.16 GAO84278.1 - 2.2e-42 144.9 0.0 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 GAO84279.1 - 1.4e-39 135.6 0.0 1.9e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF604 PF04646.7 GAO84280.1 - 4.1e-08 32.7 0.0 5.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 GAO84280.1 - 9.8e-05 21.6 0.0 0.00024 20.4 0.0 1.5 1 1 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.8 GAO84280.1 - 0.074 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Serine hydrolase SRF-TF PF00319.13 GAO84281.1 - 1.5e-23 81.7 0.2 2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 GAO84281.1 - 0.11 10.4 0.2 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein T2SJ PF11612.3 GAO84281.1 - 0.34 10.6 3.3 5.1 6.7 0.4 2.1 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein J Herpes_LMP2 PF07415.6 GAO84281.1 - 1.8 7.0 3.7 2.9 6.3 2.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Mg_trans_NIPA PF05653.9 GAO84282.1 - 5e-09 35.5 3.5 5e-09 35.5 2.4 2.6 2 1 1 3 3 3 1 Magnesium transporter NIPA EamA PF00892.15 GAO84282.1 - 0.1 12.6 17.6 0.43 10.6 0.1 3.2 3 0 0 3 3 3 0 EamA-like transporter family vATP-synt_E PF01991.13 GAO84283.1 - 5.2e-59 198.8 11.5 6e-59 198.6 8.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF1488 PF07369.6 GAO84283.1 - 0.034 13.9 5.0 0.24 11.2 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1488) NTS PF15447.1 GAO84283.1 - 0.045 14.1 0.1 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 DUF4288 PF14119.1 GAO84283.1 - 0.21 11.7 6.4 32 4.7 0.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) DUF2462 PF09495.5 GAO84283.1 - 4.1 8.2 7.0 7 7.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) SEN1_N PF12726.2 GAO84285.1 - 2.5e-230 766.3 9.9 3.3e-230 766.0 6.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 GAO84285.1 - 2e-67 227.2 0.6 2e-67 227.2 0.4 2.3 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 GAO84285.1 - 8.4e-61 204.8 0.0 1.6e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain E1-E2_ATPase PF00122.15 GAO84285.1 - 3e-12 46.0 0.7 5.8e-12 45.1 0.0 1.7 2 0 0 2 2 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 GAO84285.1 - 1.9e-11 43.7 0.0 5.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO84285.1 - 2.2e-11 44.2 0.0 8.8e-11 42.3 0.0 2.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_19 PF13245.1 GAO84285.1 - 1.9e-10 40.3 0.2 6.6e-10 38.6 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain Hydrolase PF00702.21 GAO84285.1 - 3.6e-10 40.6 0.5 5.6e-09 36.7 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_30 PF13604.1 GAO84285.1 - 2.3e-08 33.8 0.0 1.4e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 GAO84285.1 - 1.2e-06 28.0 0.0 4e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 GAO84285.1 - 3.4e-06 26.7 0.0 0.13 11.8 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 GAO84285.1 - 0.015 15.1 0.0 0.068 12.9 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 GAO84285.1 - 0.028 13.3 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 GAO84285.1 - 0.038 13.4 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hydrolase_3 PF08282.7 GAO84285.1 - 0.053 13.1 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-CCHC_3 PF13917.1 GAO84285.1 - 3.3 7.5 10.3 18 5.1 6.0 2.5 1 1 1 2 2 2 0 Zinc knuckle Robl_LC7 PF03259.12 GAO84286.1 - 0.00018 20.9 0.3 0.033 13.7 0.0 3.1 3 0 0 3 3 3 2 Roadblock/LC7 domain Aminotran_5 PF00266.14 GAO84287.1 - 9.4e-31 106.8 1.3 2.2e-23 82.6 0.3 4.1 1 1 1 2 2 2 2 Aminotransferase class-V Cyclin PF08613.6 GAO84287.1 - 3.9e-14 53.2 0.0 8.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAO84287.1 - 0.0042 16.6 0.0 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.1 GAO84289.1 - 5.4e-38 130.4 0.0 8.9e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNase_NucA_NucB PF14040.1 GAO84289.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Transp_cyt_pur PF02133.10 GAO84290.1 - 1.7e-99 333.3 39.7 2.1e-99 333.0 27.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ipi1_N PF12333.3 GAO84291.1 - 1.8e-29 101.6 0.1 7.2e-29 99.7 0.0 2.1 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 GAO84291.1 - 0.0093 16.4 2.0 1.9 9.0 0.4 2.7 1 1 1 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 GAO84291.1 - 0.056 13.7 1.3 0.071 13.4 0.2 1.6 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 GAO84291.1 - 0.059 13.4 3.6 0.64 10.2 0.2 2.9 3 0 0 3 3 3 0 HEAT repeat Exonuc_VIII PF06630.6 GAO84291.1 - 0.13 11.5 0.1 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII HlyIII PF03006.15 GAO84292.1 - 1.5e-42 145.5 17.4 1.8e-42 145.2 12.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related HSP9_HSP12 PF04119.7 GAO84293.1 - 2.4e-06 27.5 0.4 4.2e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 AreA_N PF07573.6 GAO84294.1 - 8.1e-41 138.4 6.6 8.1e-41 138.4 4.6 3.5 4 0 0 4 4 4 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 GAO84294.1 - 1.2e-16 59.7 1.9 2.9e-16 58.4 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 GAO84294.1 - 7e-14 51.1 3.9 1.5e-13 50.0 2.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn_clus PF00172.13 GAO84295.1 - 3.2e-08 33.3 6.5 4.6e-08 32.8 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 GAO84297.1 - 2.3e-14 53.2 0.0 3.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO84297.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO84297.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold NUMOD3 PF07460.6 GAO84297.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) MFS_1 PF07690.11 GAO84298.1 - 7.8e-29 100.4 27.5 7.8e-29 100.4 19.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CreD PF06123.7 GAO84298.1 - 0.072 11.6 1.8 0.2 10.1 1.3 1.6 2 0 0 2 2 2 0 Inner membrane protein CreD Bac_luciferase PF00296.15 GAO84299.1 - 2.9e-61 207.2 0.6 5.3e-61 206.4 0.4 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase zf-C2H2 PF00096.21 GAO84299.1 - 2e-10 40.3 12.5 2.3e-05 24.4 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO84299.1 - 2.7e-09 36.8 8.7 1.4e-06 28.2 2.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO84299.1 - 1.6e-08 34.2 8.1 0.00016 21.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 GAO84299.1 - 0.0084 16.2 7.9 0.055 13.7 1.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 GAO84299.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAO84299.1 - 0.13 12.1 4.0 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 GAO84299.1 - 9 6.1 6.9 1.1 9.1 0.7 2.3 2 1 1 3 3 3 0 BED zinc finger CrtC PF07143.6 GAO84300.1 - 3.9e-09 36.2 0.5 3.9e-09 36.2 0.3 2.0 2 0 0 2 2 2 1 Hydroxyneurosporene synthase (CrtC) Pyr_redox_3 PF13738.1 GAO84301.1 - 1.4e-21 77.4 0.0 2.3e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO84301.1 - 4.8e-17 61.3 0.0 1.5e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO84301.1 - 7e-14 51.5 0.1 4e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO84301.1 - 3.3e-07 30.3 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO84301.1 - 1.9e-05 24.6 0.0 5.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO84301.1 - 0.00012 21.8 0.1 0.00084 19.1 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 GAO84301.1 - 0.024 13.5 0.2 5.5 5.7 0.0 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAO84301.1 - 0.031 13.3 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Sugar_tr PF00083.19 GAO84303.1 - 6.4e-71 239.2 23.7 8.6e-51 172.9 1.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO84303.1 - 2.1e-24 85.9 34.0 1.5e-17 63.3 8.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO84303.1 - 0.0051 15.0 11.9 0.0092 14.2 3.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAO84304.1 - 1.2e-08 34.2 0.0 2.7e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84304.1 - 2.5e-07 30.4 10.3 4.7e-07 29.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tash_PEST PF07708.6 GAO84304.1 - 3.9 7.5 5.4 0.92 9.5 0.7 2.2 2 0 0 2 2 2 0 Tash protein PEST motif Methyltransf_24 PF13578.1 GAO84305.1 - 2.8e-14 53.8 0.0 4.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 GAO84305.1 - 7.8e-05 21.8 0.0 0.00014 20.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO84305.1 - 0.00014 22.3 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 GAO84305.1 - 0.0093 15.4 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.7 GAO84305.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase MFS_1 PF07690.11 GAO84306.1 - 3.8e-30 104.7 38.0 6.5e-30 104.0 26.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trypsin_2 PF13365.1 GAO84307.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 GAO84307.1 - 0.0036 16.2 0.0 0.043 12.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C4 Trypsin PF00089.21 GAO84307.1 - 0.0079 15.8 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin p450 PF00067.17 GAO84308.1 - 2.9e-30 105.2 0.0 5.4e-29 101.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_7 PF00840.15 GAO84310.1 - 6.6e-134 446.5 20.7 1.3e-132 442.2 14.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAO84310.1 - 7.9e-13 47.8 13.2 7.9e-13 47.8 9.2 3.6 3 1 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAO84310.1 - 0.0018 18.2 3.3 0.0018 18.2 2.3 2.3 2 0 0 2 2 2 1 Toxin 7 Ank_2 PF12796.2 GAO84312.1 - 2e-24 85.7 0.0 1.3e-09 38.2 0.0 5.0 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO84312.1 - 3.4e-18 65.2 2.2 2.2e-06 27.7 0.0 6.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO84312.1 - 4.8e-13 49.2 0.3 0.11 12.9 0.0 6.9 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAO84312.1 - 1.1e-11 43.9 5.0 0.016 14.9 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeat NACHT PF05729.7 GAO84312.1 - 5.2e-07 29.4 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 GAO84312.1 - 7e-07 28.8 0.0 1.2 9.6 0.0 6.0 5 0 0 5 5 4 2 Ankyrin repeat AAA_16 PF13191.1 GAO84312.1 - 8.6e-05 22.5 0.0 0.00026 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO84312.1 - 0.00055 20.0 0.0 0.0028 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAO84312.1 - 0.06 14.1 0.0 0.34 11.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO84312.1 - 0.075 11.8 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 GAO84312.1 - 0.11 12.7 0.0 0.47 10.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 GAO84312.1 - 0.13 11.2 3.3 0.68 8.8 0.1 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.1 GAO84312.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAO84312.1 - 0.18 12.2 0.1 11 6.5 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein RCC1_2 PF13540.1 GAO84312.1 - 7.7 6.2 19.9 0.37 10.4 1.0 4.6 5 0 0 5 5 4 0 Regulator of chromosome condensation (RCC1) repeat adh_short PF00106.20 GAO84313.1 - 8.4e-21 74.5 0.4 1.6e-20 73.6 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO84313.1 - 3.7e-09 36.4 0.2 5e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO84313.1 - 6.3e-08 32.6 0.0 8.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO84313.1 - 5.4e-06 26.0 0.0 6.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAO84313.1 - 0.00041 19.3 0.1 0.00063 18.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAO84313.1 - 0.001 19.1 0.3 0.0034 17.4 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO84313.1 - 0.055 12.3 0.1 0.11 11.3 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein Glyco_hydro_43 PF04616.9 GAO84314.1 - 6.7e-34 117.2 7.9 5.3e-33 114.3 5.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.20 GAO84315.1 - 2.1e-27 96.0 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84315.1 - 1.3e-17 64.4 0.0 1.7e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84315.1 - 3.9e-15 55.9 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO84315.1 - 1e-07 31.1 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAO84315.1 - 5.2e-07 29.3 0.0 1.3e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAO84315.1 - 0.00071 19.0 0.1 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.3 GAO84315.1 - 0.0058 16.3 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 GAO84315.1 - 0.091 13.1 0.1 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_2_N PF02837.13 GAO84315.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain GST_N PF02798.15 GAO84316.1 - 2e-15 56.7 0.0 5.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO84316.1 - 1.7e-14 53.7 0.0 4.3e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO84316.1 - 2.7e-14 52.8 0.5 3.4e-13 49.4 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO84316.1 - 2.4e-12 46.6 0.0 1.2e-11 44.3 0.0 2.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO84316.1 - 2.3e-07 30.6 2.0 3.6e-07 29.9 0.1 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO84316.1 - 0.0019 18.6 0.9 0.0052 17.2 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain TPP_enzyme_N PF02776.13 GAO84317.1 - 2e-33 115.3 0.1 4.1e-33 114.2 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO84317.1 - 1.9e-18 66.5 0.0 3.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAO84317.1 - 7.1e-15 54.9 0.2 1.9e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TauD PF02668.11 GAO84318.1 - 4.1e-14 52.8 0.6 3.4e-11 43.2 0.0 2.7 2 1 1 3 3 3 2 Taurine catabolism dioxygenase TauD, TfdA family Hce2 PF14856.1 GAO84320.1 - 9.5e-28 95.9 2.0 1.7e-27 95.1 1.4 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor FA_hydroxylase PF04116.8 GAO84320.1 - 6.1e-14 52.4 1.1 6.1e-14 52.4 0.7 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_18 PF00704.23 GAO84320.1 - 0.0037 16.7 0.4 0.0053 16.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Zn_clus PF00172.13 GAO84321.1 - 1.9e-08 34.0 12.0 3.8e-08 33.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO84321.1 - 2.3e-05 23.1 0.1 0.00047 18.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain RTA1 PF04479.8 GAO84322.1 - 1.6e-18 67.0 2.9 2.4e-18 66.4 2.0 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 GAO84323.1 - 1.8e-27 95.9 23.7 2e-25 89.2 14.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Spt4 PF06093.8 GAO84323.1 - 0.17 11.7 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger MFS_1 PF07690.11 GAO84324.1 - 3.5e-30 104.9 27.3 4.5e-30 104.5 18.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF63 PF01889.12 GAO84324.1 - 0.026 14.6 1.0 0.042 13.9 0.1 1.8 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 Acyl_transf_3 PF01757.17 GAO84324.1 - 0.43 9.3 32.4 0.16 10.8 8.8 3.2 2 1 1 3 3 3 0 Acyltransferase family WCOR413 PF05562.6 GAO84324.1 - 0.79 9.2 5.3 0.8 9.2 0.2 2.7 3 0 0 3 3 3 0 Cold acclimation protein WCOR413 zf-CCHC PF00098.18 GAO84325.1 - 0.0087 15.9 2.2 13 5.8 0.0 3.5 3 0 0 3 3 3 2 Zinc knuckle Defensin_propep PF00879.13 GAO84325.1 - 0.047 13.6 0.3 0.09 12.7 0.2 1.4 1 0 0 1 1 1 0 Defensin propeptide Collagen PF01391.13 GAO84325.1 - 0.3 10.6 15.9 1.9 8.0 0.4 3.9 4 0 0 4 4 4 0 Collagen triple helix repeat (20 copies) DUF3328 PF11807.3 GAO84326.1 - 1e-59 201.8 0.2 1.3e-59 201.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) VSP PF03302.8 GAO84327.1 - 0.012 14.2 0.7 0.018 13.7 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Cu_bind_like PF02298.12 GAO84327.1 - 0.031 14.0 0.1 0.072 12.8 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain DUF1183 PF06682.7 GAO84327.1 - 0.095 12.2 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1191 PF06697.7 GAO84327.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) FAD_binding_3 PF01494.14 GAO84328.1 - 2.2e-16 59.8 0.1 0.00022 20.4 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 GAO84328.1 - 2.4e-07 30.0 0.0 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO84328.1 - 1.2e-06 28.4 0.1 2.7e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO84328.1 - 0.00039 20.7 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO84328.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAO84328.1 - 0.011 15.5 0.0 0.038 13.8 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAO84328.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 GAO84328.1 - 0.094 11.7 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAO84328.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO84328.1 - 0.1 11.3 0.0 0.58 8.9 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.13 GAO84328.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 GAO84328.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAO84328.1 - 0.16 11.7 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAO84330.1 - 2.1e-33 115.4 36.1 2.6e-31 108.6 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2762 PF10960.3 GAO84330.1 - 0.009 15.7 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2762) DUF1049 PF06305.6 GAO84330.1 - 6.2 6.3 0.0 6.2 6.3 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1049) Pol_alpha_B_N PF08418.5 GAO84331.1 - 0.05 13.1 6.3 0.06 12.8 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_TAF50 PF03326.8 GAO84331.1 - 0.25 10.2 8.8 0.31 9.9 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Macoilin PF09726.4 GAO84331.1 - 7.3 4.7 7.8 8.3 4.5 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1962 PF09227.5 GAO84332.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Glyco_transf_25 PF01755.12 GAO84333.1 - 0.016 14.8 0.5 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) SKG6 PF08693.5 GAO84334.1 - 0.022 14.0 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.7 GAO84334.1 - 0.032 13.6 5.2 0.038 13.4 2.0 2.1 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Alpha_GJ PF03229.8 GAO84334.1 - 1.7 8.9 19.4 0.096 13.0 7.2 2.1 1 1 1 2 2 2 0 Alphavirus glycoprotein J DUF963 PF06131.6 GAO84335.1 - 0.47 9.7 25.4 0.92 8.8 17.6 1.5 1 1 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) FAP PF07174.6 GAO84335.1 - 0.53 9.5 8.0 0.58 9.4 5.5 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF959 PF06121.9 GAO84337.1 - 0.11 12.0 0.9 0.11 12.1 0.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) PhyH PF05721.8 GAO84339.1 - 1.2e-12 48.2 0.0 1.8e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_transf_8 PF01501.15 GAO84339.1 - 3.9e-11 42.7 0.0 1.4e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 DNA_pol_viral_N PF00242.12 GAO84340.1 - 1.7 7.5 15.6 2.5 7.0 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Fringe PF02434.11 GAO84341.1 - 6.7e-06 25.4 0.2 0.00012 21.4 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 GAO84341.1 - 0.047 13.3 1.5 0.11 12.2 1.0 1.6 1 0 0 1 1 1 0 PAN domain ADH_N PF08240.7 GAO84342.1 - 2.9e-23 81.6 0.6 6.1e-23 80.6 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO84342.1 - 6.8e-15 54.7 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO84342.1 - 7.2e-05 22.0 0.1 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO84342.1 - 0.0026 17.3 0.1 0.0058 16.2 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.17 GAO84342.1 - 0.0095 16.4 0.0 5.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.10 GAO84342.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAO84342.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 GAO84342.1 - 0.055 13.2 0.4 0.095 12.5 0.3 1.3 1 0 0 1 1 1 0 ThiF family MAF_flag10 PF01973.13 GAO84342.1 - 0.16 11.4 0.1 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF115 Glyco_hydro_75 PF07335.6 GAO84343.1 - 1.7e-45 154.6 0.1 2.7e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF521 PF04412.8 GAO84344.1 - 1.5e-151 504.4 0.0 1.9e-151 504.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 GAO84344.1 - 1.9e-33 113.9 0.2 3.7e-33 113.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF126 Zip PF02535.17 GAO84345.1 - 7.1e-48 163.2 0.8 9.9e-48 162.7 0.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RP1-2 PF12042.3 GAO84345.1 - 0.066 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain Tannase PF07519.6 GAO84346.1 - 2.4e-124 415.6 5.9 3.4e-124 415.1 4.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 GAO84346.1 - 0.00032 20.6 0.0 0.00085 19.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84346.1 - 0.0041 16.8 0.1 0.15 11.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cation_efflux PF01545.16 GAO84347.1 - 4.8e-34 117.7 7.6 6.4e-34 117.3 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family YlbE PF14003.1 GAO84347.1 - 4 7.5 5.7 0.46 10.5 0.8 1.7 2 0 0 2 2 2 0 YlbE-like protein Acetyltransf_1 PF00583.19 GAO84349.1 - 6.2e-10 38.9 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO84349.1 - 3.2e-09 36.8 0.1 5e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO84349.1 - 3.4e-07 30.1 0.3 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO84349.1 - 7.4e-07 29.3 0.1 1e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO84349.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein AA_permease_2 PF13520.1 GAO84350.1 - 2.6e-42 144.8 42.6 3.1e-42 144.6 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO84350.1 - 4.5e-23 81.3 35.6 6.4e-23 80.8 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 GAO84351.1 - 1.8e-59 201.2 0.9 2.1e-59 201.0 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 GAO84352.1 - 1.2e-41 142.8 0.0 2.4e-41 141.8 0.0 1.4 1 1 1 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO84352.1 - 1.2e-08 34.4 0.0 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAO84352.1 - 6.6e-08 31.6 0.0 1.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAO84352.1 - 3.2e-06 25.6 0.0 4.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAO84352.1 - 3.2e-05 23.1 0.0 4.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 GAO84352.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Allinase Aminotran_1_2 PF00155.16 GAO84353.1 - 1.1e-24 87.1 0.0 1.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAO84353.1 - 0.00068 18.3 0.0 0.0055 15.3 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase PrpF PF04303.8 GAO84354.1 - 1.7e-115 385.7 0.1 1.9e-115 385.5 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_S10 PF00450.17 GAO84356.1 - 4.2e-99 332.5 0.3 5.8e-99 332.0 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAO84356.1 - 0.0047 16.8 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 GAO84357.1 - 1e-64 218.8 0.0 1.4e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO84357.1 - 0.00011 21.5 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAO84357.1 - 0.00084 18.1 0.2 0.0047 15.7 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAO84357.1 - 0.16 10.9 0.0 0.36 9.7 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAO84358.1 - 2.6e-42 145.0 0.0 3.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO84358.1 - 4.2e-07 29.4 0.0 6.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAO84358.1 - 2e-06 27.1 0.0 3.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAO84358.1 - 5.5e-06 24.9 0.0 8e-06 24.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO84358.1 - 6.6e-06 25.1 0.0 1.7e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Vps54 PF07928.7 GAO84358.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Vps54-like protein NmrA PF05368.8 GAO84361.1 - 9.6e-23 80.6 0.0 1.2e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAO84361.1 - 0.00068 18.7 0.1 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 GAO84361.1 - 0.0056 16.7 0.1 0.022 14.7 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO84361.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 KR domain ThiF PF00899.16 GAO84361.1 - 0.019 14.8 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.13 GAO84361.1 - 0.025 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 GAO84361.1 - 0.041 13.9 0.2 0.15 12.1 0.1 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 GAO84361.1 - 0.099 13.1 0.0 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AP_endonuc_2 PF01261.19 GAO84362.1 - 1.3e-23 83.4 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Amidohydro_1 PF01979.15 GAO84363.1 - 2.8e-34 119.2 0.0 3.6e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAO84363.1 - 0.00055 19.2 2.2 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAO84363.1 - 0.00076 19.2 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 GAO84363.1 - 0.0044 15.9 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 GAO84363.1 - 0.031 14.3 0.2 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase Toxin_29 PF08116.6 GAO84363.1 - 0.051 13.3 1.0 0.18 11.6 0.7 1.9 1 0 0 1 1 1 0 PhTx neurotoxin family YhhN PF07947.9 GAO84364.1 - 8.7e-46 155.6 7.4 1e-45 155.4 5.2 1.0 1 0 0 1 1 1 1 YhhN-like protein DUF3357 PF11837.3 GAO84364.1 - 0.11 12.2 0.2 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) RTA1 PF04479.8 GAO84365.1 - 3.2e-49 167.4 2.1 3.2e-49 167.4 1.5 1.7 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 GAO84365.1 - 0.0017 17.0 6.5 0.0069 15.0 1.9 2.3 2 1 1 3 3 3 2 Fungal specific transcription factor domain RTA1 PF04479.8 GAO84366.1 - 8.9e-60 201.9 15.7 1.3e-59 201.4 10.9 1.2 1 0 0 1 1 1 1 RTA1 like protein ADH_zinc_N PF00107.21 GAO84368.1 - 6.7e-26 90.3 0.1 1.1e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO84368.1 - 1.1e-17 65.0 0.0 2.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO84368.1 - 6.6e-13 48.3 0.1 4.1e-12 45.8 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAO84368.1 - 0.00025 20.6 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 GAO84368.1 - 0.0023 17.1 0.0 0.0055 15.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAO84368.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CMAS PF02353.15 GAO84368.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fungal_trans_2 PF11951.3 GAO84369.1 - 8.6e-32 110.1 5.9 1.3e-31 109.5 4.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84369.1 - 1.2e-06 28.3 9.8 2e-06 27.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 GAO84370.1 - 4.8e-26 90.8 0.9 9.1e-26 89.9 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO84370.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Beta-lactamase PF00144.19 GAO84371.1 - 1.2e-41 142.8 0.0 1.8e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAO84371.1 - 0.21 10.7 0.0 0.7 9.1 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_12 PF01670.11 GAO84372.1 - 1.3e-32 112.7 0.2 2.1e-32 112.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DPBB_1 PF03330.13 GAO84373.1 - 1.6e-06 27.9 0.0 6.1e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel BNR PF02012.15 GAO84373.1 - 0.022 14.5 0.5 0.022 14.5 0.4 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Barwin PF00967.12 GAO84373.1 - 0.054 13.1 0.9 0.14 11.8 0.3 1.9 1 1 0 1 1 1 0 Barwin family RHS_repeat PF05593.9 GAO84374.1 - 8.3e-06 25.8 13.2 0.56 10.4 1.1 5.4 4 1 1 5 5 5 4 RHS Repeat Asp_Glu_race PF01177.17 GAO84375.1 - 8.1e-17 61.8 0.0 9.5e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TIM-br_sig_trns PF09370.5 GAO84375.1 - 0.026 13.5 0.1 0.091 11.8 0.0 1.7 1 1 1 2 2 2 0 TIM-barrel signal transduction protein Abhydrolase_3 PF07859.8 GAO84376.1 - 3.5e-17 62.6 0.0 4.9e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84376.1 - 4.5e-12 45.6 0.0 2.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO84376.1 - 3.2e-10 39.9 0.0 5.3e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO84376.1 - 9.6e-09 35.4 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAO84376.1 - 1.5e-06 27.8 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 GAO84376.1 - 8.8e-05 22.0 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 GAO84376.1 - 0.00021 20.1 0.3 0.0006 18.6 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 GAO84376.1 - 0.0024 16.8 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LIP PF03583.9 GAO84376.1 - 0.0073 15.5 0.0 0.045 12.9 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Esterase PF00756.15 GAO84376.1 - 0.0079 15.6 0.2 0.098 12.0 0.2 2.2 1 1 0 1 1 1 1 Putative esterase PhoPQ_related PF10142.4 GAO84376.1 - 0.036 12.5 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DLH PF01738.13 GAO84376.1 - 0.12 11.6 0.0 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 GAO84377.1 - 2.9e-33 115.0 27.8 4.2e-33 114.5 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84377.1 - 1.1e-10 40.7 2.8 1.1e-10 40.7 2.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO84377.1 - 4.9e-06 25.0 2.0 7.8e-06 24.3 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2140 PF09911.4 GAO84377.1 - 0.09 11.9 0.1 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Cupin_2 PF07883.6 GAO84378.1 - 2.9e-15 55.5 0.3 1.1e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Fungal_trans PF04082.13 GAO84378.1 - 1e-10 40.9 0.4 1.8e-10 40.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_3 PF05899.7 GAO84378.1 - 2.8e-05 23.4 0.1 0.001 18.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) DUF2360 PF10152.4 GAO84378.1 - 0.012 15.8 2.0 1.7 8.9 0.7 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AraC_binding PF02311.14 GAO84378.1 - 0.061 13.0 0.5 0.22 11.2 0.3 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_1 PF00190.17 GAO84378.1 - 0.089 12.2 0.0 0.92 8.9 0.0 2.3 2 0 0 2 2 2 0 Cupin CENP-C_C PF11699.3 GAO84378.1 - 0.096 12.6 0.2 2.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Mif2/CENP-C like TcdB_toxin_midC PF12255.3 GAO84379.1 - 1.7e-19 69.9 0.1 3.1e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region TcdB_toxin_midN PF12256.3 GAO84379.1 - 5.6e-16 58.4 1.2 3.8e-09 36.2 0.0 4.2 2 2 1 3 3 3 3 Insecticide toxin TcdB middle/N-terminal region VCBS PF13517.1 GAO84379.1 - 2.5e-05 24.5 0.2 0.00082 19.6 0.2 2.6 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAO84379.1 - 0.0089 15.6 0.2 0.033 13.9 0.1 2.0 1 0 0 1 1 1 1 FG-GAP repeat SpvB PF03534.8 GAO84380.1 - 8.7e-20 70.9 0.1 1.2e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein DUF4066 PF13278.1 GAO84382.1 - 5e-27 94.2 0.0 6.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO84382.1 - 4.2e-15 55.4 0.0 6.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Zn_clus PF00172.13 GAO84383.1 - 2.1e-07 30.6 9.1 4.3e-07 29.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO84383.1 - 6.4e-05 21.9 0.2 0.00011 21.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_34 PF05637.7 GAO84384.1 - 1.1e-17 64.3 4.1 1.8e-15 57.0 2.9 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 GAO84384.1 - 0.0054 16.5 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Evr1_Alr PF04777.8 GAO84385.1 - 0.00063 19.5 0.2 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Jacalin PF01419.12 GAO84386.1 - 0.018 14.9 0.1 0.57 10.0 0.0 2.9 2 1 1 3 3 3 0 Jacalin-like lectin domain HSDR_N PF04313.9 GAO84386.1 - 0.13 11.9 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) ABC_tran PF00005.22 GAO84387.1 - 1.4e-27 96.6 0.2 2.3e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAO84387.1 - 1e-14 54.2 13.2 1.5e-14 53.7 9.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 GAO84387.1 - 1.6e-07 31.6 1.2 4.6e-05 23.5 0.8 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAO84387.1 - 0.00061 19.0 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO84387.1 - 0.0032 16.8 0.2 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO84387.1 - 0.0042 16.3 0.8 0.087 12.0 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 GAO84387.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAO84387.1 - 0.008 15.2 0.1 2.5 7.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 GAO84387.1 - 0.0092 14.9 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 GAO84387.1 - 0.014 16.1 0.0 0.028 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO84387.1 - 0.019 14.9 2.5 0.027 14.4 0.8 2.0 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAO84387.1 - 0.071 12.7 0.7 0.65 9.6 0.2 2.3 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 GAO84387.1 - 0.082 13.0 0.9 0.6 10.2 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAO84387.1 - 0.11 12.0 2.5 0.15 11.6 0.9 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1981 PF09324.5 GAO84387.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) MobB PF03205.9 GAO84387.1 - 0.26 10.9 1.0 0.96 9.1 0.2 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B polyprenyl_synt PF00348.12 GAO84388.1 - 6e-34 117.0 0.0 9.6e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAO84388.1 - 4.8e-10 39.1 0.6 0.00037 19.7 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Phe_hydrox_dim PF07976.7 GAO84389.1 - 1.5e-23 83.2 0.4 5.3e-16 58.6 0.1 2.4 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 GAO84389.1 - 6.3e-20 71.5 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Gly_transf_sug PF04488.10 GAO84391.1 - 1.7e-11 44.3 0.0 2.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 GAO84391.1 - 0.0045 16.2 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RTA1 PF04479.8 GAO84392.1 - 3.3e-49 167.4 2.9 5.2e-49 166.7 2.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Cation_ATPase_C PF00689.16 GAO84392.1 - 4.7 6.6 7.9 0.3 10.5 0.7 2.1 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4131 PF13567.1 GAO84392.1 - 6.3 6.1 10.7 3.5 7.0 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Lipase_GDSL_2 PF13472.1 GAO84393.1 - 5.4e-11 42.9 0.0 6.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO84393.1 - 2.1e-09 37.5 0.1 6.3e-09 36.0 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.16 GAO84397.1 - 9.1e-49 166.1 0.1 1.6e-33 115.9 0.0 2.0 1 1 0 2 2 2 2 Aminotransferase class-III SpvD PF05563.7 GAO84397.1 - 0.037 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD Aminotran_4 PF01063.14 GAO84398.1 - 3.1e-17 62.8 0.0 1.4e-16 60.6 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class IV PAS_9 PF13426.1 GAO84400.1 - 0.00015 22.1 0.0 0.00033 20.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF2422 PF10337.4 GAO84401.1 - 7.6e-37 127.1 0.0 7.6e-37 127.1 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAO84401.1 - 1.4e-12 47.6 13.6 1.4e-12 47.6 9.4 2.4 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAO84401.1 - 0.00056 19.5 0.0 0.0042 16.7 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 GAO84401.1 - 0.035 13.9 12.5 0.18 11.6 6.6 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF939) Abhydrolase_1 PF00561.15 GAO84402.1 - 4.8e-22 78.6 0.0 2.1e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 GAO84402.1 - 1.8e-17 63.1 0.0 6.6e-17 61.2 0.0 2.0 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_6 PF12697.2 GAO84402.1 - 2.2e-06 27.6 0.0 7.4e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Prominin PF05478.6 GAO84403.1 - 0.12 9.9 4.3 0.19 9.2 3.0 1.2 1 0 0 1 1 1 0 Prominin MLANA PF14991.1 GAO84403.1 - 0.77 9.7 10.7 0.6 10.1 0.2 2.6 3 0 0 3 3 3 0 Protein melan-A Herpes_LMP1 PF05297.6 GAO84403.1 - 1.2 7.9 10.6 2.2 7.1 0.9 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2207 PF09972.4 GAO84403.1 - 1.3 7.5 6.5 0.24 9.9 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2079 PF09852.4 GAO84403.1 - 2 7.0 10.7 0.22 10.2 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF4131 PF13567.1 GAO84403.1 - 4 6.8 8.3 13 5.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2633 PF11119.3 GAO84403.1 - 8.4 6.1 7.1 0.83 9.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) FAD_binding_4 PF01565.18 GAO84404.1 - 8.1e-16 57.7 0.3 1.8e-15 56.6 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO84404.1 - 1.4e-11 44.1 0.2 6e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 GAO84404.1 - 0.036 13.2 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Zn_clus PF00172.13 GAO84405.1 - 1.1e-06 28.4 9.0 1.9e-06 27.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 GAO84406.1 - 9.2e-37 126.4 0.1 1.2e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain peroxidase PF00141.18 GAO84407.1 - 2.3e-46 158.1 0.0 4.3e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase AOX PF01786.12 GAO84407.1 - 2.9e-09 36.6 0.0 1.3e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Alternative oxidase bZIP_1 PF00170.16 GAO84407.1 - 3.4e-06 26.8 16.2 1.5e-05 24.8 10.2 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAO84407.1 - 0.00048 19.8 21.2 0.0036 17.0 10.7 2.6 1 1 1 2 2 2 2 Basic region leucine zipper Kinesin-relat_1 PF12711.2 GAO84407.1 - 0.018 15.4 3.7 0.038 14.3 2.6 1.4 1 0 0 1 1 1 0 Kinesin motor DUF972 PF06156.8 GAO84407.1 - 0.019 15.2 1.9 0.045 14.1 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2959 PF11172.3 GAO84407.1 - 0.067 12.9 1.7 0.14 11.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) bZIP_Maf PF03131.12 GAO84407.1 - 0.86 9.9 13.5 1.3 9.3 8.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans_2 PF11951.3 GAO84408.1 - 4.3e-09 35.4 5.6 7.3e-06 24.8 3.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain HALZ PF02183.13 GAO84408.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SGL PF08450.7 GAO84409.1 - 3e-05 23.5 0.4 0.011 15.1 0.2 2.1 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 GAO84409.1 - 0.055 12.5 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller p450 PF00067.17 GAO84410.1 - 2.1e-24 85.8 0.0 1.1e-22 80.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 GDH_N PF12466.3 GAO84410.1 - 1.3 9.1 3.9 13 5.9 0.2 2.9 3 0 0 3 3 3 0 Glutamate dehydrogenase N terminal Flavoprotein PF02441.14 GAO84411.1 - 3.6e-26 91.3 0.0 5.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.11 GAO84412.1 - 1.3e-123 412.5 0.0 1.5e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Glyco_hydro_3 PF00933.16 GAO84413.1 - 2.6e-84 282.7 0.0 3.6e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO84413.1 - 6.6e-54 182.8 0.0 1.2e-53 181.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO84413.1 - 2e-24 85.2 0.2 8e-24 83.3 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain COesterase PF00135.23 GAO84414.1 - 6.2e-56 190.2 0.0 9.4e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO84414.1 - 0.00097 18.7 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 GAO84416.1 - 1.2e-12 48.0 1.3 7.5e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAO84416.1 - 9.1e-05 22.1 0.1 0.00063 19.4 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAO84416.1 - 0.00018 21.3 0.0 0.061 13.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Permease PF02405.11 GAO84416.1 - 0.044 13.2 0.1 0.083 12.3 0.1 1.4 1 0 0 1 1 1 0 Permease GFA PF04828.9 GAO84418.1 - 1e-22 79.8 0.1 1.3e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NMO PF03060.10 GAO84419.1 - 9.5e-47 159.7 0.9 1.5e-44 152.5 0.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 GAO84419.1 - 2.2e-08 33.3 0.4 3.6e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAO84419.1 - 3.5e-07 29.4 0.8 8.5e-05 21.5 0.3 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO84419.1 - 5e-06 25.6 0.0 7.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 GAO84419.1 - 0.0061 15.5 0.2 0.0096 14.9 0.1 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 GAO84419.1 - 0.095 11.9 0.2 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein ADH_zinc_N PF00107.21 GAO84420.1 - 2e-28 98.5 0.2 3.6e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO84420.1 - 6.8e-19 69.0 0.1 2.3e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO84420.1 - 5.8e-05 22.8 0.1 0.00032 20.4 0.0 2.3 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAO84420.1 - 0.008 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 GAO84420.1 - 0.073 12.6 0.8 0.18 11.3 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PhzC-PhzF PF02567.11 GAO84421.1 - 9.4e-43 146.4 0.0 1.8e-42 145.4 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein NMO PF03060.10 GAO84422.1 - 2.4e-63 214.3 0.2 5.2e-63 213.1 0.1 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAO84422.1 - 2.5e-11 43.1 0.0 1.6e-05 23.9 0.2 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAO84422.1 - 0.0026 16.6 0.5 0.0051 15.7 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAO84422.1 - 0.039 12.8 0.4 0.086 11.7 0.2 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase Aminotran_1_2 PF00155.16 GAO84423.1 - 6.4e-39 133.9 0.0 7.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAO84423.1 - 1.8e-11 43.4 0.0 2.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAO84423.1 - 1.9e-05 23.1 0.1 2.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAO84423.1 - 4.5e-05 22.7 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.8 GAO84423.1 - 7.8e-05 21.4 0.0 9.7e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.12 GAO84423.1 - 0.0001 21.4 0.2 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 GAO84423.1 - 0.0052 15.3 0.0 0.0077 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Amidohydro_3 PF07969.6 GAO84424.1 - 1.3e-55 189.2 0.0 1.5e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAO84424.1 - 4.3e-08 32.8 0.0 1.2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAO84424.1 - 4.2e-07 29.9 0.0 0.0056 16.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAO84424.1 - 2.1e-06 27.9 1.8 0.021 14.8 0.0 3.4 3 1 0 3 3 3 2 Amidohydrolase PALP PF00291.20 GAO84425.1 - 1.8e-45 155.5 0.0 2.1e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TPR_11 PF13414.1 GAO84426.1 - 2.8e-09 36.4 11.0 4.2e-07 29.5 0.1 4.0 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAO84426.1 - 5.7e-09 35.2 9.7 8.8e-05 22.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO84426.1 - 1.7e-06 28.4 13.8 0.016 15.9 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84426.1 - 2.2e-05 24.7 6.4 1.4 9.2 0.3 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO84426.1 - 3.3e-05 23.3 0.1 0.45 10.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO84426.1 - 5.4e-05 22.6 3.5 0.013 15.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAO84426.1 - 0.14 12.6 3.4 3.1 8.4 0.3 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO84426.1 - 0.17 12.6 9.7 33 5.5 0.0 5.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAO84426.1 - 0.42 10.5 4.0 1.7 8.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO84426.1 - 0.59 10.1 11.8 3.3 7.7 1.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.11 GAO84427.1 - 0.01 15.5 0.1 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 GAO84427.1 - 1.8 9.0 36.4 1.6 9.2 4.2 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Aminotran_4 PF01063.14 GAO84428.1 - 9.8e-28 97.1 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV GST_N_3 PF13417.1 GAO84429.1 - 9e-15 54.6 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO84429.1 - 4.8e-14 52.1 0.0 7.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO84429.1 - 3.6e-13 49.4 0.0 7.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO84429.1 - 2e-10 40.4 0.0 7.2e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO84429.1 - 1.1e-06 28.3 0.1 2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO84429.1 - 1.4e-05 25.4 0.2 2.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAO84429.1 - 0.054 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain DUF2278 PF10042.4 GAO84430.1 - 2.6e-75 252.6 0.2 3.3e-75 252.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 GAO84430.1 - 1.4e-06 28.3 0.1 3.6e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Lamin Tail Domain RicinB_lectin_2 PF14200.1 GAO84431.1 - 3.2e-09 37.1 0.2 8.3e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Antirestrict PF03230.8 GAO84431.1 - 0.42 10.6 0.1 0.42 10.6 0.0 1.9 2 1 0 2 2 2 0 Antirestriction protein p450 PF00067.17 GAO84432.1 - 4.9e-64 216.5 0.0 6.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transpep_BrtH PF14399.1 GAO84433.1 - 4.8e-22 78.6 0.0 1.1e-21 77.5 0.0 1.5 1 1 0 1 1 1 1 NlpC/p60-like transpeptidase Peptidase_C70 PF12385.3 GAO84433.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.1 GAO84433.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 GAO84433.1 - 0.0031 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family PAF-AH_p_II PF03403.8 GAO84434.1 - 1.3e-17 63.1 0.0 9.2e-10 37.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAO84434.1 - 8.6e-14 51.5 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO84434.1 - 2.2e-10 40.8 0.1 3.4e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO84434.1 - 3.3e-05 22.8 0.0 0.00013 20.9 0.0 1.8 2 1 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 GAO84434.1 - 0.018 14.5 0.0 0.051 13.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84434.1 - 0.076 12.2 1.1 0.26 10.4 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase PF07224.6 GAO84434.1 - 0.077 11.7 0.2 0.99 8.1 0.2 2.1 1 1 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.20 GAO84434.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans_2 PF11951.3 GAO84435.1 - 0.0075 14.9 0.0 0.0092 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.19 GAO84436.1 - 2.9e-40 138.7 0.2 2.1e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAO84436.1 - 1.3e-15 57.2 2.9 5.1e-14 51.9 2.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO84436.1 - 2e-14 53.3 0.6 7.3e-14 51.5 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO84436.1 - 1e-07 30.8 0.3 6.3e-06 24.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO84436.1 - 2.3e-07 30.0 0.3 3.6e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO84436.1 - 1.1e-06 28.6 0.0 9.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO84436.1 - 1.8e-06 28.1 0.0 0.00054 20.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO84436.1 - 4.8e-06 26.8 0.2 0.0021 18.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO84436.1 - 5.7e-06 25.4 0.1 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 GAO84436.1 - 5.6e-05 22.3 0.9 8.3e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 GAO84436.1 - 8e-05 21.8 1.5 0.00012 21.2 0.8 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO84436.1 - 8.9e-05 21.5 0.8 0.00019 20.4 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAO84436.1 - 0.00024 20.3 0.2 0.00042 19.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAO84436.1 - 0.00097 18.9 1.2 0.33 10.6 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GDI PF00996.13 GAO84436.1 - 0.099 10.9 0.1 1.4 7.1 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor DUF427 PF04248.7 GAO84437.1 - 2.8e-24 84.6 3.5 1.8e-22 78.7 0.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF427) MFS_1 PF07690.11 GAO84438.1 - 1.1e-16 60.5 31.2 1.7e-16 59.8 21.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAO84439.1 - 7.2e-24 84.1 75.7 3.1e-18 65.6 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_fiss_reg PF05308.6 GAO84439.1 - 8.8 5.6 6.1 11 5.2 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAD_binding_3 PF01494.14 GAO84440.1 - 2.9e-15 56.2 0.9 4.9e-14 52.1 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO84440.1 - 5.2e-10 38.7 1.3 9.6e-05 21.4 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO84440.1 - 1e-06 28.6 0.6 2.5e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO84440.1 - 1.8e-06 27.9 1.1 6.3e-06 26.2 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO84440.1 - 4e-05 23.9 2.8 0.0019 18.5 2.1 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO84440.1 - 6.5e-05 21.9 2.8 0.00012 21.0 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO84440.1 - 0.00036 19.7 1.3 0.00058 19.0 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO84440.1 - 0.00081 18.3 1.3 0.00084 18.3 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAO84440.1 - 0.0037 15.8 1.3 0.0058 15.1 0.9 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 GAO84440.1 - 0.0097 15.0 0.4 0.58 9.1 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAO84440.1 - 0.076 12.7 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 GAO84440.1 - 0.081 12.0 0.5 0.15 11.1 0.3 1.4 1 1 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 GAO84440.1 - 0.15 11.6 1.9 0.29 10.7 0.5 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAO84440.1 - 0.15 12.0 0.2 0.3 11.1 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO84440.1 - 0.2 10.2 1.0 0.34 9.4 0.3 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAO84440.1 - 0.32 10.7 2.5 12 5.6 0.6 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_2 PF00891.13 GAO84441.1 - 4.4e-37 127.5 0.0 5.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO84441.1 - 8.7e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84441.1 - 1.4e-06 27.9 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84441.1 - 1.4e-05 25.6 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84441.1 - 5.2e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO84441.1 - 8.8e-05 21.9 0.0 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 GAO84441.1 - 0.0024 18.3 0.0 0.0072 16.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO84441.1 - 0.0048 16.9 0.1 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAO84441.1 - 0.0075 15.7 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 GAO84441.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DREV PF05219.7 GAO84441.1 - 0.056 12.3 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 GAO84441.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 GAO84441.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_4 PF02390.12 GAO84441.1 - 0.16 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 GAO84442.1 - 7e-47 159.9 0.0 1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 GAO84443.1 - 1e-77 261.0 0.6 1.9e-77 260.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO84443.1 - 4.1e-57 193.9 0.0 1.2e-56 192.4 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO84443.1 - 3.7e-34 117.1 1.7 4.9e-34 116.7 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO84443.1 - 1.1e-28 100.9 0.0 3.6e-28 99.3 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAO84443.1 - 9.5e-25 86.6 8.6 1.1e-12 48.0 1.3 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAO84443.1 - 4.3e-24 85.1 0.1 9.8e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 GAO84443.1 - 3.1e-09 37.0 3.3 2.7e-05 24.1 0.0 3.8 3 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAO84443.1 - 0.00018 20.5 0.1 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1275 PF06912.6 GAO84443.1 - 0.075 12.2 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) GFA PF04828.9 GAO84444.1 - 2.7e-12 46.4 8.7 1.1e-10 41.3 1.3 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 GAO84444.1 - 0.013 14.7 0.3 0.045 13.0 0.2 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding zf-CSL PF05207.8 GAO84444.1 - 3.6 7.1 9.4 0.44 10.0 0.3 3.0 3 0 0 3 3 3 0 CSL zinc finger Glyco_transf_90 PF05686.7 GAO84445.1 - 4.7e-23 81.5 0.0 3.4e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 NPP1 PF05630.6 GAO84447.1 - 2.6e-57 193.8 0.0 3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Peroxidase_2 PF01328.12 GAO84448.1 - 4.7e-16 58.3 0.3 4.1e-15 55.2 0.2 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.6 GAO84449.1 - 1.7e-15 56.5 12.1 2.8e-15 55.8 8.4 1.4 1 0 0 1 1 1 1 CFEM domain GMC_oxred_C PF05199.8 GAO84450.1 - 3.6e-30 105.1 0.0 6.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAO84450.1 - 4.2e-28 98.3 0.0 1.5e-17 63.7 0.0 3.1 2 1 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.1 GAO84450.1 - 0.002 18.0 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO84450.1 - 0.0037 17.3 0.1 0.26 11.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO84450.1 - 0.0075 16.1 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO84450.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HHH PF00633.18 GAO84450.1 - 0.035 13.8 0.1 6 6.7 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif FAD_binding_2 PF00890.19 GAO84450.1 - 0.053 12.3 0.5 0.099 11.4 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 GAO84450.1 - 0.063 12.1 0.4 2.8 6.7 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO84450.1 - 0.22 9.9 0.1 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MaoC_dehydratas PF01575.14 GAO84451.1 - 4.4e-26 90.6 0.0 9.2e-26 89.6 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAO84451.1 - 1.4e-07 31.3 0.0 0.25 11.1 0.0 3.3 3 0 0 3 3 3 3 N-terminal half of MaoC dehydratase Glyco_hydro_42 PF02449.10 GAO84452.1 - 8.7e-11 41.5 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 GAO84452.1 - 5.2e-06 26.0 0.0 1.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 GAO84452.1 - 0.19 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 CRAL_TRIO PF00650.15 GAO84453.1 - 7.2e-23 80.8 0.0 9.8e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain PMM PF03332.8 GAO84453.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase AA_permease_2 PF13520.1 GAO84455.1 - 1.2e-45 155.8 58.1 1.5e-45 155.5 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO84455.1 - 3.5e-25 88.2 49.6 6e-25 87.5 34.4 1.2 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 GAO84456.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO84456.1 - 2.9e-05 24.1 0.1 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO84456.1 - 0.00043 20.4 0.1 0.0014 18.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO84456.1 - 0.0051 16.6 0.4 0.029 14.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO84456.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase E1-E2_ATPase PF00122.15 GAO84457.1 - 5.1e-52 176.1 1.4 5.1e-52 176.1 1.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO84457.1 - 2.2e-37 128.3 2.8 2.2e-37 128.3 1.9 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO84457.1 - 1.5e-27 97.4 0.0 1.3e-26 94.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO84457.1 - 3.1e-17 62.2 0.0 6.1e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAO84457.1 - 6.3e-16 57.6 0.1 2.6e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAO84457.1 - 1.8e-15 57.6 0.0 4.8e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO84457.1 - 0.0014 18.2 0.1 0.0059 16.2 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 GAO84457.1 - 0.41 11.0 9.0 0.07 13.4 1.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 GAO84457.1 - 1.4 7.4 5.3 2.1 6.8 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Chitin_synth_1 PF01644.12 GAO84458.1 - 9.9e-70 233.5 0.0 1.6e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAO84458.1 - 3.3e-27 93.9 0.1 8e-27 92.7 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAO84458.1 - 3.5e-23 81.8 0.0 2.7e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAO84458.1 - 1.4e-11 44.4 0.1 1.4e-11 44.4 0.1 3.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO84458.1 - 2.2e-08 34.2 0.0 5.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CBM_4_9 PF02018.12 GAO84459.1 - 5.9e-10 39.2 0.5 1.4e-09 38.0 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Opy2 PF09463.5 GAO84459.1 - 5.8 7.0 14.6 9.2 6.4 0.4 3.8 3 0 0 3 3 3 0 Opy2 protein ABC2_membrane PF01061.19 GAO84460.1 - 6e-82 273.8 56.0 5.2e-43 146.6 16.4 2.8 4 0 0 4 4 2 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO84460.1 - 8.6e-36 121.7 6.3 9.6e-34 115.1 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 GAO84460.1 - 3.9e-33 114.6 0.0 4.9e-17 62.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 GAO84460.1 - 1.2e-17 63.7 0.1 3.2e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 GAO84460.1 - 2.1e-08 33.6 48.5 3.3e-08 32.9 11.2 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 GAO84460.1 - 3.3e-07 29.8 0.1 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO84460.1 - 2.1e-05 24.6 0.3 0.0022 18.0 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAO84460.1 - 2.5e-05 23.5 0.1 0.00022 20.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAO84460.1 - 2.8e-05 24.0 0.1 0.022 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO84460.1 - 5.7e-05 22.5 0.4 0.031 13.7 0.1 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain cobW PF02492.14 GAO84460.1 - 0.00061 19.2 0.6 0.013 14.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAO84460.1 - 0.0013 19.5 0.0 0.39 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO84460.1 - 0.0016 18.7 0.1 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO84460.1 - 0.0018 17.5 0.0 0.27 10.4 0.0 3.3 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 GAO84460.1 - 0.0024 17.5 0.2 2.6 7.8 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 GAO84460.1 - 0.011 15.4 1.1 2.4 7.7 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.1 GAO84460.1 - 0.011 15.8 1.2 0.45 10.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA PF00004.24 GAO84460.1 - 0.032 14.4 0.1 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAO84460.1 - 0.045 13.7 0.5 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 GAO84460.1 - 0.062 13.2 1.0 1.8 8.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 GAO84460.1 - 0.18 12.3 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 GAO84460.1 - 0.19 11.1 0.4 8.6 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain FAD_binding_4 PF01565.18 GAO84463.1 - 1.1e-17 63.8 1.7 2.1e-17 62.8 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO84463.1 - 2.3e-05 24.2 0.1 6.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like CBM_14 PF01607.19 GAO84465.1 - 6e-07 29.2 6.6 1.1e-06 28.4 4.6 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Nop14 PF04147.7 GAO84465.1 - 1.4 6.7 13.5 1.6 6.5 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family PD40 PF07676.7 GAO84466.1 - 1.8e-05 24.2 0.3 0.018 14.6 0.1 3.2 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 GAO84466.1 - 0.003 16.1 0.0 0.27 9.7 0.0 2.6 3 0 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region RTA1 PF04479.8 GAO84467.1 - 7.7e-54 182.5 3.6 7.7e-54 182.5 2.5 2.1 2 0 0 2 2 2 1 RTA1 like protein DUF3176 PF11374.3 GAO84467.1 - 9e-39 131.7 1.7 9e-39 131.7 1.2 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3176) CFEM PF05730.6 GAO84468.1 - 1.1e-09 37.9 12.2 1.7e-09 37.3 8.4 1.3 1 0 0 1 1 1 1 CFEM domain DUF2976 PF11190.3 GAO84468.1 - 3.4 7.2 9.1 9.2 5.8 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) Ank_2 PF12796.2 GAO84469.1 - 9.5e-127 413.6 12.1 3.2e-21 75.4 0.0 9.7 3 3 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84469.1 - 9.1e-78 252.4 26.7 9.9e-07 28.2 0.0 19.6 19 0 0 19 19 19 16 Ankyrin repeat Ank_3 PF13606.1 GAO84469.1 - 7.8e-67 214.5 17.0 6.2e-06 25.9 0.0 19.6 21 0 0 21 21 21 13 Ankyrin repeat Ank_4 PF13637.1 GAO84469.1 - 1.5e-60 200.6 25.6 1.3e-08 35.1 0.0 14.8 6 5 9 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO84469.1 - 1.7e-54 180.6 27.8 4.3e-10 39.5 0.1 13.4 7 2 7 14 14 14 9 Ankyrin repeats (many copies) F-box-like PF12937.2 GAO84469.1 - 5.1e-05 22.9 0.8 0.00012 21.6 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO84469.1 - 0.0015 18.0 0.2 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain RGS PF00615.14 GAO84470.1 - 3.1e-12 46.6 0.0 5.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Glyoxalase_2 PF12681.2 GAO84470.1 - 9.1e-08 32.6 0.1 2.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAO84470.1 - 0.0012 18.7 0.1 0.0046 16.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7TM_GPCR_Sru PF10322.4 GAO84470.1 - 0.014 14.5 5.7 0.026 13.6 4.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Beta-lactamase PF00144.19 GAO84472.1 - 1e-40 139.7 0.1 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase AA_permease PF00324.16 GAO84473.1 - 5.4e-106 354.7 40.2 6.6e-106 354.5 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO84473.1 - 2.4e-28 98.8 41.2 3.2e-28 98.4 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease SchA_CurD PF04486.7 GAO84474.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 SchA/CurD like domain Amino_oxidase PF01593.19 GAO84475.1 - 4.1e-52 177.7 0.1 6.6e-51 173.7 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO84475.1 - 2.8e-15 56.0 0.0 8.6e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO84475.1 - 7.9e-08 31.5 0.2 2.3e-06 26.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO84475.1 - 8.5e-06 25.6 0.0 0.0093 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO84475.1 - 2.5e-05 24.5 0.1 0.00027 21.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO84475.1 - 3.9e-05 22.3 0.0 0.00065 18.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAO84475.1 - 0.0012 18.9 0.0 0.05 13.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO84475.1 - 0.0012 17.9 0.0 0.0098 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO84475.1 - 0.0025 16.9 0.1 0.0057 15.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAO84475.1 - 0.0054 15.8 0.6 0.0084 15.1 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAO84475.1 - 0.0067 15.3 0.1 0.015 14.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 GAO84475.1 - 0.017 14.5 0.1 0.042 13.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAO84475.1 - 0.046 13.3 0.1 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAO84475.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAO84475.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 GAO84475.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 GAO84475.1 - 0.17 11.6 0.0 1.7 8.3 0.0 2.3 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 GAO84476.1 - 1.2e-36 126.1 37.4 1.2e-36 126.1 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 GAO84476.1 - 0.0082 14.5 6.5 0.016 13.5 4.4 1.7 1 1 0 1 1 1 1 Ferroportin1 (FPN1) DIOX_N PF14226.1 GAO84477.1 - 3.9e-35 120.8 0.1 6.3e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO84477.1 - 1.6e-16 60.3 0.0 2.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CHAT PF12770.2 GAO84478.1 - 9.7e-35 120.0 0.0 2.7e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_19 PF14559.1 GAO84478.1 - 0.055 13.8 8.9 7 7.0 0.0 5.7 6 1 0 7 7 7 0 Tetratricopeptide repeat S100PBPR PF15427.1 GAO84479.1 - 0.099 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 S100P-binding protein Methyltransf_PK PF05891.7 GAO84480.1 - 5.4e-71 238.3 0.0 6.2e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 GAO84480.1 - 6e-05 22.8 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84480.1 - 0.0007 20.1 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_VERT_large PF04441.8 GAO84480.1 - 0.0092 14.1 0.2 0.28 9.2 0.0 2.0 2 0 0 2 2 2 2 Poxvirus early transcription factor (VETF), large subunit Methyltransf_11 PF08241.7 GAO84480.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF77 PF01910.12 GAO84480.1 - 0.02 14.5 0.4 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF77 Methyltransf_12 PF08242.7 GAO84480.1 - 0.054 13.9 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SET PF00856.23 GAO84481.1 - 2.5e-19 70.1 0.0 7.9e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 SET domain Gp_dh_C PF02800.15 GAO84482.1 - 1.1e-71 239.3 0.0 2.1e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAO84482.1 - 5.8e-59 198.3 0.1 1.1e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO84482.1 - 0.023 14.6 0.1 0.089 12.7 0.0 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 GAO84482.1 - 0.074 12.5 0.1 0.31 10.6 0.0 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 GAO84486.1 - 5.9e-30 104.7 1.3 6.8e-30 104.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO84486.1 - 5.8e-23 81.6 1.7 8.3e-23 81.1 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84486.1 - 8.2e-11 41.8 1.3 1.2e-08 34.8 0.1 2.2 1 1 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.12 GAO84486.1 - 2e-05 23.6 0.5 7.6e-05 21.7 0.1 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain DUF1776 PF08643.5 GAO84486.1 - 0.00039 19.6 0.0 0.00056 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAO84486.1 - 0.00067 19.1 0.2 0.00091 18.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO84486.1 - 0.0048 16.9 1.2 0.095 12.6 0.4 2.1 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 GAO84486.1 - 0.16 12.3 4.6 5.2 7.5 0.5 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF4243 PF14027.1 GAO84487.1 - 3.5e-79 266.6 0.1 4e-79 266.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Sugar_tr PF00083.19 GAO84488.1 - 1.4e-86 290.8 23.5 2.3e-86 290.1 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84488.1 - 3.3e-24 85.2 36.2 1.2e-14 53.8 8.2 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO84488.1 - 4.4e-12 45.4 0.4 1e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain UPF0075 PF03702.9 GAO84489.1 - 1.4e-82 277.5 0.0 1.9e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Fungal_trans_2 PF11951.3 GAO84489.1 - 6e-13 48.1 5.9 1.9e-11 43.1 4.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 GAO84490.1 - 3.1e-26 92.0 17.1 4.1e-26 91.5 11.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Sugar_tr PF00083.19 GAO84491.1 - 2.7e-132 441.5 29.7 4.4e-132 440.8 20.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Ras PF00071.17 GAO84491.1 - 2.2e-28 98.6 0.0 4.6e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Ras family MFS_1 PF07690.11 GAO84491.1 - 2.2e-23 82.5 45.2 2.7e-16 59.2 14.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 GAO84491.1 - 2.7e-18 65.3 1.1 2.7e-18 65.3 0.8 2.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Miro PF08477.8 GAO84491.1 - 5.6e-16 59.0 0.0 1.3e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO84491.1 - 4.6e-09 35.7 0.0 7.4e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAO84491.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAO84491.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 GAO84491.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MobB PF03205.9 GAO84491.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAO84491.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 GAO84491.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF4064 PF13273.1 GAO84491.1 - 8.9 6.4 15.6 9 6.4 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Glyco_hyd_65N_2 PF14498.1 GAO84492.1 - 1.5e-54 185.1 0.0 3.6e-54 183.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Peptidase_S10 PF00450.17 GAO84493.1 - 1.1e-100 337.7 7.2 1.5e-100 337.3 5.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NAD_binding_8 PF13450.1 GAO84494.1 - 5.9e-12 45.4 2.4 1e-11 44.6 0.1 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO84494.1 - 3e-09 36.2 0.1 1.2e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO84494.1 - 1.5e-08 34.1 0.1 2.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO84494.1 - 7.5e-08 31.6 0.6 1.1e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAO84494.1 - 1.5e-07 30.8 0.0 2.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 GAO84494.1 - 4.1e-06 25.5 0.2 6.1e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 GAO84494.1 - 1e-05 25.8 0.1 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO84494.1 - 2.8e-05 24.0 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO84494.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO84494.1 - 0.00051 19.0 0.1 0.00081 18.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 GAO84494.1 - 0.0021 17.2 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAO84494.1 - 0.0036 16.4 0.7 0.0058 15.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAO84494.1 - 0.0079 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 GAO84494.1 - 0.017 14.5 1.6 0.018 14.4 0.3 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 GAO84494.1 - 0.019 14.5 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 GAO84494.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 GAO84494.1 - 0.068 11.7 0.3 0.11 11.1 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 GAO84494.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 GAO84494.1 - 0.086 12.6 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Asp PF00026.18 GAO84496.1 - 2.2e-42 145.4 0.6 2.6e-42 145.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAO84496.1 - 2.4e-05 24.7 0.1 0.00074 19.9 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 GAO84496.1 - 0.00025 20.6 0.4 0.0021 17.6 0.1 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RVP PF00077.15 GAO84496.1 - 0.0051 16.7 0.1 0.054 13.4 0.0 2.4 2 1 0 2 2 2 1 Retroviral aspartyl protease RTA1 PF04479.8 GAO84498.1 - 2.4e-53 180.9 2.1 3.2e-53 180.5 1.5 1.1 1 0 0 1 1 1 1 RTA1 like protein Amidase PF01425.16 GAO84499.1 - 9.1e-87 291.7 0.0 1.1e-86 291.4 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF2278 PF10042.4 GAO84500.1 - 6.6e-77 257.8 0.0 8.6e-77 257.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 GAO84500.1 - 4.7e-05 23.4 0.0 0.00071 19.6 0.0 2.3 1 1 0 1 1 1 1 Lamin Tail Domain DUF3632 PF12311.3 GAO84501.1 - 1.1e-37 129.6 0.0 1.5e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) UPF0167 PF03691.9 GAO84501.1 - 0.084 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) HK97-gp10_like PF04883.7 GAO84501.1 - 0.1 13.5 0.1 0.23 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Bradykinin PF06753.7 GAO84501.1 - 0.11 12.0 0.2 0.25 10.8 0.2 1.6 1 0 0 1 1 1 0 Bradykinin NAD_binding_2 PF03446.10 GAO84502.1 - 1.4e-22 80.2 0.1 3.3e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAO84502.1 - 3.9e-10 40.0 0.1 9.7e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAO84502.1 - 6.9e-06 25.5 0.1 2e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAO84502.1 - 2.4e-05 23.5 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAO84502.1 - 0.00028 21.0 0.0 0.00056 20.0 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAO84502.1 - 0.00079 19.1 0.0 0.0035 17.0 0.0 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAO84502.1 - 0.0014 18.3 0.1 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAO84502.1 - 0.0048 16.8 0.0 0.028 14.4 0.0 2.2 1 1 0 1 1 1 1 TrkA-N domain DmpG_comm PF07836.6 GAO84502.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 DmpG-like communication domain Ank_2 PF12796.2 GAO84503.1 - 2e-17 63.3 0.0 4.6e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84503.1 - 1.6e-14 52.8 0.3 0.00015 21.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 GAO84503.1 - 2.3e-12 45.8 0.4 0.012 15.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAO84503.1 - 6.4e-12 45.6 0.1 1.5e-05 25.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO84503.1 - 1.1e-06 28.7 0.1 0.14 12.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SnoaL_2 PF12680.2 GAO84503.1 - 0.017 15.5 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Fe-S_assembly PF04384.8 GAO84503.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Fungal_trans PF04082.13 GAO84504.1 - 1.5e-12 46.9 0.1 2.2e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84504.1 - 3.6e-08 33.1 9.2 6.8e-08 32.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 GAO84505.1 - 4.4e-25 89.0 0.0 8.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO84505.1 - 1.6e-17 63.2 0.0 2.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAO84505.1 - 0.0049 16.9 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding RTA1 PF04479.8 GAO84506.1 - 1.3e-54 185.0 8.4 1.3e-54 185.0 5.8 1.8 2 0 0 2 2 2 1 RTA1 like protein Sugar_tr PF00083.19 GAO84507.1 - 4.7e-40 137.5 15.4 8.4e-23 80.6 5.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO84507.1 - 7.2e-22 77.5 17.0 4.2e-14 52.0 5.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_34 PF05637.7 GAO84508.1 - 6.2e-07 29.1 1.1 0.00026 20.5 0.0 2.8 2 1 1 3 3 3 2 galactosyl transferase GMA12/MNN10 family Metallophos PF00149.23 GAO84509.1 - 1.6e-42 145.1 0.0 3e-42 144.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAO84509.1 - 3.1e-14 52.8 0.0 9.3e-14 51.2 0.0 1.9 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAO84509.1 - 4.2e-09 35.4 0.4 7.5e-08 31.3 0.3 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAO84509.1 - 0.036 13.9 0.0 0.14 12.0 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PLA2_B PF01735.13 GAO84510.1 - 3e-189 629.2 5.2 3.5e-189 629.0 3.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.11 GAO84511.1 - 1.8e-44 151.8 42.2 1.8e-44 151.8 29.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84511.1 - 1.7e-10 40.0 14.4 1.7e-10 40.0 10.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 GAO84512.1 - 4.1e-60 203.6 0.0 6.4e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF924 PF06041.6 GAO84513.1 - 2.1e-61 206.9 1.7 3.2e-61 206.3 1.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) CIA30 PF08547.7 GAO84514.1 - 8.3e-36 123.2 0.0 1e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) adh_short PF00106.20 GAO84515.1 - 1.9e-23 83.1 0.4 3.1e-23 82.5 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84515.1 - 8.4e-19 68.2 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84515.1 - 4.1e-11 42.8 0.0 1.3e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAO84515.1 - 9.9e-06 25.6 0.5 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAO84515.1 - 1.6e-05 24.4 0.1 3.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAO84515.1 - 7e-05 22.1 0.0 0.0053 15.9 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.8 GAO84515.1 - 0.0023 17.2 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 GAO84515.1 - 0.041 12.7 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1524 PF07510.6 GAO84516.1 - 3.2e-13 49.7 0.0 3.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) DJ-1_PfpI PF01965.19 GAO84517.1 - 2.2e-24 85.5 0.1 3.2e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAO84517.1 - 1.5e-16 59.6 0.1 2.9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 GAO84517.1 - 0.0044 16.3 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 GAO84517.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 Redoxin PF08534.5 GAO84518.1 - 2.8e-39 133.9 0.0 3.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAO84518.1 - 3.3e-14 52.6 0.0 4.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Stirrup PF09061.1 GAO84518.1 - 0.017 15.0 0.0 0.83 9.5 0.0 2.6 3 0 0 3 3 3 0 Stirrup Oxidored_FMN PF00724.15 GAO84519.1 - 9.6e-65 218.7 0.0 5.7e-64 216.2 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.3 GAO84520.1 - 5.2e-22 77.9 0.5 7.5e-22 77.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 GAO84521.1 - 1.3e-165 551.1 0.0 1.6e-165 550.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAO84521.1 - 6.5e-20 71.0 0.0 1.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAO84521.1 - 1e-10 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Amidohydro_3 PF07969.6 GAO84522.1 - 4.1e-56 190.9 3.2 4.7e-56 190.7 2.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAO84522.1 - 1.1e-10 41.1 0.0 3.5e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAO84522.1 - 3.4e-09 36.8 1.4 7.5e-08 32.3 1.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO84522.1 - 0.00069 19.7 15.6 0.0042 17.1 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase RicinB_lectin_2 PF14200.1 GAO84523.1 - 3.6e-05 24.0 0.1 0.034 14.5 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Hemopexin PF00045.14 GAO84523.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Hemopexin S-methyl_trans PF02574.11 GAO84524.1 - 4.3e-28 98.5 0.0 5.4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AA_permease PF00324.16 GAO84525.1 - 7.3e-114 380.7 43.7 8.9e-114 380.4 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO84525.1 - 1.6e-37 129.0 48.0 1.9e-37 128.8 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 GAO84526.1 - 5.3e-48 163.5 17.6 8e-48 162.9 12.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84526.1 - 7.8e-12 44.5 5.8 7.8e-12 44.5 4.0 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 GAO84526.1 - 0.0016 16.6 5.0 0.0016 16.6 3.5 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector ubiquitin PF00240.18 GAO84526.1 - 0.0053 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family adh_short PF00106.20 GAO84528.1 - 4.5e-19 68.9 0.0 5.7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84528.1 - 5.3e-11 42.4 0.0 7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO84528.1 - 1.8e-10 40.9 0.0 2.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO84528.1 - 0.00067 19.1 0.0 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO84528.1 - 0.011 15.7 0.1 0.032 14.2 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 GAO84528.1 - 0.06 12.0 0.0 0.16 10.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAO84528.1 - 0.083 11.7 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Med15_fungi PF05397.7 GAO84528.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 15 MFS_1 PF07690.11 GAO84529.1 - 3.8e-45 154.1 44.2 3.8e-45 154.1 30.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO84529.1 - 1.5e-10 39.9 11.4 2.3e-10 39.3 7.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAO84530.1 - 2.3e-15 56.1 0.6 4.6e-15 55.1 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84530.1 - 1.3e-08 34.6 8.3 3e-08 33.4 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO84531.1 - 8.8e-17 60.8 0.0 1.6e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84531.1 - 1.2e-08 34.6 11.6 3.5e-08 33.2 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 GAO84532.1 - 5.9e-23 81.3 0.0 8.2e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO84532.1 - 5.6e-15 55.8 0.4 1.5e-14 54.4 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO84532.1 - 5.5e-07 28.8 0.2 9.5e-07 28.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAO84532.1 - 8.1e-05 22.9 0.1 0.00017 21.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO84532.1 - 0.01 15.7 0.3 0.021 14.7 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 GAO84532.1 - 0.019 14.0 0.4 0.14 11.1 0.3 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 GAO84532.1 - 0.038 14.4 0.4 0.12 12.8 0.3 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.6 GAO84534.1 - 1.2e-10 41.6 1.5 2.9e-08 33.9 0.0 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PHP PF02811.14 GAO84535.1 - 2.4e-06 27.4 0.1 6.2e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 PHP domain Nbas_N PF15492.1 GAO84535.1 - 0.044 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal MFS_1 PF07690.11 GAO84537.1 - 1.9e-38 132.0 24.5 2.3e-38 131.8 17.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84537.1 - 5.8e-12 44.9 14.6 1.1e-11 44.0 10.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.16 GAO84538.1 - 0.089 12.5 5.9 0.13 12.0 4.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family Ank_2 PF12796.2 GAO84539.1 - 6.2e-17 61.7 0.0 2.4e-06 27.7 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO84539.1 - 2.2e-11 42.8 0.2 0.00019 21.3 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 GAO84539.1 - 6.6e-10 38.2 1.0 3.2e-05 23.5 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 GAO84539.1 - 1.5e-08 34.8 3.4 0.0062 17.0 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO84539.1 - 5.6e-05 23.2 0.1 0.16 12.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) NAD_binding_10 PF13460.1 GAO84540.1 - 3.2e-09 37.0 0.0 4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO84540.1 - 0.0012 17.8 0.0 0.065 12.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAO84540.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO84540.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 GAO84540.1 - 0.021 14.7 0.3 0.075 12.9 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 GAO84540.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAO84540.1 - 0.044 12.6 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 GAO84540.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain bZIP_1 PF00170.16 GAO84541.1 - 8.4e-08 32.0 9.0 1.5e-07 31.2 6.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO84541.1 - 1.2e-05 25.0 9.7 2.1e-05 24.2 6.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAO84541.1 - 0.00093 19.4 5.5 0.0017 18.6 3.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor FTA4 PF13093.1 GAO84541.1 - 0.029 13.8 0.4 0.045 13.1 0.3 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DivIC PF04977.10 GAO84541.1 - 0.052 13.0 2.1 0.092 12.2 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.6 GAO84541.1 - 0.18 11.5 1.7 0.34 10.6 1.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.1 GAO84541.1 - 3.7 7.2 6.0 1.9 8.1 0.4 2.3 1 1 1 2 2 2 0 Alternative WD40 repeat motif Fungal_trans PF04082.13 GAO84542.1 - 6.8e-19 67.7 0.6 1.1e-18 67.1 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO84543.1 - 2.4e-39 135.0 23.1 3.2e-39 134.6 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAO84543.1 - 0.0048 16.4 1.7 0.0048 16.4 1.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1445 PF07286.7 GAO84544.1 - 4.4e-59 198.2 0.0 6.2e-59 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.13 GAO84545.1 - 7.4e-12 44.6 0.0 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84545.1 - 3.7e-08 33.1 13.2 6.9e-08 32.2 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAO84546.1 - 9e-65 218.9 0.0 1e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.26 GAO84547.1 - 5.3e-12 45.5 0.0 8.7e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain AAA_23 PF13476.1 GAO84547.1 - 0.0026 18.1 3.3 0.0066 16.8 2.3 1.6 1 0 0 1 1 1 1 AAA domain Ycf1 PF05758.7 GAO84547.1 - 0.44 8.1 4.0 0.73 7.4 2.8 1.2 1 0 0 1 1 1 0 Ycf1 zf-DHHC PF01529.15 GAO84547.1 - 0.72 9.2 0.9 1.3 8.4 0.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Paramyxo_ncap PF00973.14 GAO84547.1 - 3.5 6.2 10.3 6.8 5.2 7.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Maf1 PF09174.5 GAO84547.1 - 4.1 7.2 5.4 1.4e+02 2.2 4.4 2.4 2 0 0 2 2 2 0 Maf1 regulator Anoctamin PF04547.7 GAO84547.1 - 7.6 5.0 2.4 11 4.4 1.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DS PF01916.12 GAO84548.1 - 5e-141 469.0 0.0 5.8e-141 468.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase zf-C3HC4_3 PF13920.1 GAO84549.1 - 6.3e-12 44.9 10.9 1.1e-11 44.2 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 GAO84549.1 - 1.3e-11 43.5 25.2 0.0027 17.3 0.1 4.8 4 0 0 4 4 4 4 MORN repeat UCH PF00443.24 GAO84549.1 - 2.1e-10 40.1 0.0 3.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 GAO84549.1 - 1.2e-05 25.4 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 2 MATH domain zf-C3HC4_2 PF13923.1 GAO84549.1 - 0.0002 21.2 9.4 0.00045 20.1 6.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 GAO84549.1 - 0.00072 18.8 0.0 0.002 17.4 0.0 1.7 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-RING_5 PF14634.1 GAO84549.1 - 0.093 12.4 11.9 0.17 11.6 8.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Nol1_Nop2_Fmu PF01189.12 GAO84550.1 - 9.4e-95 317.2 0.0 1.8e-94 316.2 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 GAO84550.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Blt1 PF12754.2 GAO84551.1 - 4.9e-70 236.5 0.0 8.1e-70 235.8 0.0 1.3 1 1 0 1 1 1 1 Cell-cycle control medial ring component DUF2407 PF10302.4 GAO84551.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_60s PF00428.14 GAO84551.1 - 0.087 13.2 0.5 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein ParD PF09386.5 GAO84551.1 - 0.13 12.4 0.1 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Antitoxin ParD Striatin PF08232.7 GAO84552.1 - 1.5e-44 151.5 7.0 1.5e-44 151.5 4.9 3.1 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 GAO84552.1 - 3.5e-30 102.7 15.3 1e-05 25.2 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 GAO84552.1 - 0.0088 15.7 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PAT1 PF09770.4 GAO84552.1 - 3.8 5.6 29.9 5 5.2 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XPA_C PF05181.7 GAO84553.1 - 1.3e-29 101.5 3.6 3.6e-29 100.1 2.5 1.8 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 GAO84553.1 - 0.018 14.8 9.2 0.07 12.9 0.8 2.9 3 0 0 3 3 3 0 YhfH-like protein XPA_N PF01286.13 GAO84553.1 - 0.022 14.3 6.9 0.022 14.3 4.8 2.1 2 0 0 2 2 2 0 XPA protein N-terminal PIG-P PF08510.7 GAO84554.1 - 4.1e-45 152.4 2.1 5.4e-45 152.0 0.2 2.0 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 GAO84554.1 - 0.052 11.5 0.0 0.069 11.1 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.7 GAO84554.1 - 9.9 6.5 9.0 17 5.7 6.2 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF221 PF02714.10 GAO84555.1 - 9.4e-108 359.9 17.2 9.4e-108 359.9 11.9 2.7 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAO84555.1 - 1.2e-40 138.5 4.1 8.8e-40 135.8 1.8 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAO84555.1 - 2.8e-29 100.8 0.7 5.9e-29 99.7 0.5 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAO84555.1 - 1.8e-14 53.9 0.2 4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Cellulase PF00150.13 GAO84556.1 - 3.8e-38 131.3 6.4 6.7e-38 130.4 4.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 GAO84556.1 - 7.5e-26 89.7 6.6 2.4e-25 88.1 1.2 3.2 4 0 0 4 4 4 1 Carbohydrate binding domain X2 DUF544 PF04424.8 GAO84557.1 - 5.2e-12 45.6 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 GAO84558.1 - 4.6e-117 390.4 0.0 6.8e-117 389.8 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 GAO84559.1 - 1.4e-64 217.1 0.0 3e-39 134.5 0.0 2.0 2 0 0 2 2 2 2 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 GAO84559.1 - 0.064 13.2 0.1 0.064 13.2 0.1 1.9 2 0 0 2 2 2 0 Pancreatic hormone peptide Rep_fac_C PF08542.6 GAO84560.1 - 2.5e-17 62.6 0.1 8.4e-17 60.9 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 GAO84560.1 - 1.8e-16 60.5 0.0 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAO84560.1 - 1.6e-13 50.6 0.0 4.3e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAO84560.1 - 2.9e-11 42.7 0.1 6.7e-09 34.9 0.0 2.4 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAO84560.1 - 9.3e-08 32.2 0.1 1.2e-06 28.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAO84560.1 - 1.8e-07 30.4 0.1 6.7e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAO84560.1 - 7e-07 29.4 0.1 0.00011 22.2 0.0 3.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAO84560.1 - 2.6e-06 27.0 0.0 7.2e-06 25.6 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 GAO84560.1 - 3.3e-06 26.7 0.0 6.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 GAO84560.1 - 3.3e-06 26.8 0.7 4.9e-05 23.0 0.5 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO84560.1 - 6.6e-06 25.0 0.0 0.042 12.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_30 PF13604.1 GAO84560.1 - 6.8e-06 25.8 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO84560.1 - 1.1e-05 25.2 0.7 6.7e-05 22.6 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 GAO84560.1 - 8.3e-05 21.6 0.0 0.00021 20.3 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAO84560.1 - 9.6e-05 22.2 0.0 0.00024 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAO84560.1 - 0.00027 20.0 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 GAO84560.1 - 0.00033 19.9 0.1 0.89 8.7 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 GAO84560.1 - 0.00038 20.0 0.1 0.0017 17.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 GAO84560.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAO84560.1 - 0.0018 17.7 0.1 0.041 13.3 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase Sigma54_activat PF00158.21 GAO84560.1 - 0.0028 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 GAO84560.1 - 0.0037 17.1 0.0 0.17 11.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 GAO84560.1 - 0.0042 16.2 0.1 0.024 13.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 GAO84560.1 - 0.005 16.3 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 GAO84560.1 - 0.0056 16.1 0.4 1.4 8.3 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 GAO84560.1 - 0.0076 15.9 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 GAO84560.1 - 0.0093 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAO84560.1 - 0.011 15.1 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAO84560.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAO84560.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAO84560.1 - 0.03 15.1 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TRAPPC-Trs85 PF12739.2 GAO84560.1 - 0.034 12.7 0.3 0.051 12.2 0.2 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RNA_helicase PF00910.17 GAO84560.1 - 0.046 13.9 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 GAO84560.1 - 0.072 11.8 0.0 1.7 7.3 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain His_Phos_2 PF00328.17 GAO84561.1 - 1.3e-10 41.1 0.3 1.4e-08 34.4 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3431 PF11913.3 GAO84562.1 - 1.4e-87 292.8 0.2 2.3e-87 292.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Pro_isomerase PF00160.16 GAO84563.1 - 4.8e-39 134.0 0.0 9.1e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 GAO84563.1 - 0.0059 16.8 0.2 0.0059 16.8 0.1 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4604) HSF_DNA-bind PF00447.12 GAO84564.1 - 2.8e-29 101.3 0.2 5.2e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 GAO84564.1 - 0.0037 17.0 1.2 0.013 15.2 0.2 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Aldo_ket_red PF00248.16 GAO84565.1 - 7.8e-21 74.1 0.0 1.8e-20 72.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family ATP_bind_4 PF01902.12 GAO84565.1 - 0.02 14.2 0.0 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 ATP-binding region Sporozoite_P67 PF05642.6 GAO84566.1 - 0.012 13.5 4.5 0.015 13.2 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.6 GAO84566.1 - 0.69 8.2 5.0 0.85 7.9 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Hamartin PF04388.7 GAO84566.1 - 0.78 8.3 5.4 0.91 8.1 3.7 1.0 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.6 GAO84566.1 - 7.3 4.5 10.9 8.7 4.2 7.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) R3H PF01424.17 GAO84567.1 - 6.3e-11 41.8 0.0 1.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 GAO84567.1 - 7.9e-07 28.5 3.2 3.6e-06 26.4 2.2 2.3 1 0 0 1 1 1 1 SUZ-C motif RRM_6 PF14259.1 GAO84567.1 - 1.4e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO84567.1 - 7.4e-06 25.5 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO84567.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 GAO84568.1 - 4.3e-22 78.0 0.0 5.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAO84568.1 - 4.6e-05 23.3 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.4 GAO84569.1 - 1.9e-80 268.6 0.5 2.2e-80 268.4 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Gp_dh_C PF02800.15 GAO84570.1 - 3.9e-75 250.5 0.0 5.9e-75 250.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAO84570.1 - 2.2e-59 199.7 0.1 6.3e-59 198.2 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO84570.1 - 0.069 12.3 0.1 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hist_deacetyl PF00850.14 GAO84571.1 - 9.8e-95 317.4 0.3 9.8e-95 317.4 0.2 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 GAO84571.1 - 1.7e-57 193.7 0.2 7.6e-57 191.6 0.0 1.9 2 0 0 2 2 2 1 Arb2 domain Bys1 PF04681.7 GAO84572.1 - 2.4e-16 59.8 0.4 2.8e-16 59.5 0.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pro_racemase PF05544.6 GAO84573.1 - 5.3e-63 212.8 0.0 6.8e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Peptidase_M16 PF00675.15 GAO84574.1 - 8.7e-30 103.4 5.3 2.1e-20 72.9 0.5 4.0 4 1 0 4 4 4 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAO84574.1 - 1.2e-28 100.0 0.0 2.8e-20 72.7 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Phage_int_SAM_1 PF02899.12 GAO84574.1 - 0.043 13.9 0.2 8 6.6 0.0 3.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Aldo_ket_red PF00248.16 GAO84575.1 - 9.6e-60 201.7 0.0 1.1e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family INCENP_ARK-bind PF03941.10 GAO84575.1 - 0.027 14.2 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region NUDIX_2 PF13869.1 GAO84576.1 - 5.9e-83 276.8 0.0 7.1e-83 276.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 GAO84576.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Lipase_3 PF01764.20 GAO84577.1 - 1.4e-38 131.6 0.0 3.5e-38 130.3 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.11 GAO84577.1 - 9.8e-10 38.1 1.2 2e-09 37.1 0.8 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.7 GAO84577.1 - 0.0098 15.4 0.1 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase Peptidase_S8 PF00082.17 GAO84577.1 - 0.019 14.0 3.4 0.027 13.6 2.3 1.2 1 0 0 1 1 1 0 Subtilase family DUF2974 PF11187.3 GAO84577.1 - 0.031 13.6 0.4 0.65 9.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAO84577.1 - 0.033 13.9 0.1 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3431 PF11913.3 GAO84578.1 - 4.9e-92 307.4 0.3 6.9e-92 306.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) CoaE PF01121.15 GAO84579.1 - 2.1e-41 141.2 0.0 3.5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 GAO84579.1 - 0.00027 21.7 0.1 0.0006 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO84579.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain BNIP3 PF06553.7 GAO84580.1 - 0.033 13.5 7.7 0.027 13.8 2.1 2.1 2 0 0 2 2 2 0 BNIP3 Syntaxin PF00804.20 GAO84580.1 - 0.07 13.2 0.7 0.17 12.0 0.5 1.7 1 0 0 1 1 1 0 Syntaxin MPP6 PF10175.4 GAO84580.1 - 0.13 12.6 1.1 0.49 10.7 0.0 2.4 2 1 0 2 2 2 0 M-phase phosphoprotein 6 zf-CHCC PF10276.4 GAO84581.1 - 1.1e-17 63.5 0.4 1.8e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.12 GAO84582.1 - 3.4e-41 139.7 0.0 3.8e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NPP1 PF05630.6 GAO84583.1 - 1.5e-06 28.0 2.7 3.2e-06 27.0 0.0 2.5 2 1 1 3 3 3 1 Necrosis inducing protein (NPP1) GFA PF04828.9 GAO84584.1 - 1.4e-09 37.7 1.3 2.7e-09 36.8 0.9 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.2 GAO84585.1 - 2.7e-08 33.4 0.2 7.4e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO84585.1 - 0.078 12.6 1.9 0.55 9.9 0.3 2.8 2 0 0 2 2 2 0 F-box domain Melibiase PF02065.13 GAO84586.1 - 6.7e-24 84.3 0.9 4.1e-20 71.8 0.7 3.3 1 1 0 1 1 1 1 Melibiase Exo_endo_phos PF03372.18 GAO84587.1 - 3.2e-23 82.9 0.0 7.4e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 GAO84587.1 - 0.24 11.3 3.9 0.31 11.0 0.6 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ_3 PF13570.1 GAO84587.1 - 1.6 9.1 6.5 0.58 10.5 0.5 3.1 3 0 0 3 3 3 0 PQQ-like domain zf-CHY PF05495.7 GAO84588.1 - 1.8e-05 24.7 9.3 0.00028 20.9 6.4 2.1 1 1 0 1 1 1 1 CHY zinc finger HypA PF01155.14 GAO84588.1 - 0.033 13.8 0.8 0.058 13.0 0.6 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-FPG_IleRS PF06827.9 GAO84588.1 - 0.079 12.6 2.1 0.24 11.0 1.4 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_3 PF14369.1 GAO84588.1 - 0.26 11.3 6.4 1.6 8.7 4.6 2.2 1 1 1 2 2 2 0 zinc-finger C1_4 PF07975.7 GAO84588.1 - 0.63 10.0 7.9 4.3 7.4 5.6 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Evr1_Alr PF04777.8 GAO84588.1 - 0.66 9.9 3.8 4.1 7.3 2.4 2.3 1 1 0 1 1 1 0 Erv1 / Alr family Zn-ribbon_8 PF09723.5 GAO84588.1 - 1.4 8.9 7.4 3.1 7.8 5.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Proteasome PF00227.21 GAO84589.1 - 6.7e-55 185.3 0.0 9.2e-55 184.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAO84589.1 - 3.3e-14 51.8 0.1 6.5e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 GAO84589.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-RanBP PF00641.13 GAO84590.1 - 9.8e-21 72.5 9.1 6.3e-11 41.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 GAO84590.1 - 2.3e-08 33.5 0.0 5.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 GAO84590.1 - 6.6e-07 29.7 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 GAO84590.1 - 8.2e-07 28.9 0.0 8e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 GAO84590.1 - 0.54 10.1 8.3 0.81 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 GAO84591.1 - 2.7e-101 338.5 0.9 2.9e-99 331.8 0.0 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAO84591.1 - 4e-08 33.4 6.5 2.2e-05 24.6 0.2 4.6 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 GAO84591.1 - 3.5e-05 23.5 4.0 0.031 14.3 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 GAO84591.1 - 6.1e-05 23.3 8.1 0.0055 17.1 0.1 4.8 5 0 0 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.2 GAO84591.1 - 0.02 14.8 0.6 0.83 9.6 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion NYD-SP28_assoc PF14775.1 GAO84591.1 - 0.32 10.7 3.2 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain PALP PF00291.20 GAO84592.1 - 1.5e-64 218.1 0.1 1.8e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 GAO84593.1 - 3.2e-56 189.3 0.0 4.6e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAO84593.1 - 1.6e-26 92.4 0.4 2.8e-26 91.6 0.3 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Tim17 PF02466.14 GAO84594.1 - 4.6e-50 168.9 8.5 6.7e-50 168.4 5.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 GAO84594.1 - 0.024 13.9 0.3 0.049 12.9 0.2 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2946 PF11162.3 GAO84594.1 - 0.045 13.9 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Fork_head_N PF08430.7 GAO84594.1 - 6.9 7.0 15.3 4.6 7.6 8.5 2.1 1 1 1 2 2 2 0 Forkhead N-terminal region DUF4048 PF13257.1 GAO84595.1 - 1.8e-92 309.6 21.4 1.8e-92 309.6 14.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) GrpE PF01025.14 GAO84595.1 - 0.0029 17.1 1.6 0.005 16.3 1.1 1.3 1 0 0 1 1 1 1 GrpE DUF4391 PF14335.1 GAO84595.1 - 0.19 11.0 1.2 0.3 10.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Bap31 PF05529.7 GAO84595.1 - 0.27 10.6 0.3 0.56 9.6 0.2 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 GAO84595.1 - 0.69 9.8 5.5 0.4 10.5 1.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 GAO84596.1 - 3.4e-73 246.0 0.0 5.2e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84596.1 - 3.7e-51 173.6 0.0 8.5e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FAD-oxidase_C PF02913.14 GAO84596.1 - 3.9e-42 144.3 0.0 8.1e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAO84596.1 - 4.4e-37 126.6 0.4 9.2e-37 125.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Kinase-like PF14531.1 GAO84596.1 - 5.2e-05 22.3 0.0 0.00013 21.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RmlD_sub_bind PF04321.12 GAO84597.1 - 2.1e-56 190.9 0.0 2.7e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAO84597.1 - 1.2e-21 77.2 0.0 2.1e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO84597.1 - 1.2e-11 44.0 0.4 9.6e-10 37.8 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO84597.1 - 4.2e-09 35.7 0.2 7.9e-07 28.2 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAO84597.1 - 3.3e-07 29.2 0.0 2.1e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO84597.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO84597.1 - 2.3e-05 24.3 0.0 0.0017 18.3 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84597.1 - 0.013 15.1 0.3 5.1 6.7 0.0 2.7 3 0 0 3 3 3 0 KR domain IGR PF09597.5 GAO84597.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif ABC2_membrane PF01061.19 GAO84599.1 - 1.4e-92 308.6 69.0 3.9e-48 163.3 14.7 3.9 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.22 GAO84599.1 - 1.1e-36 126.1 0.0 1.7e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO84599.1 - 5.5e-33 112.7 13.1 6e-30 102.9 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 GAO84599.1 - 1.8e-19 69.6 0.7 4.7e-19 68.2 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO84599.1 - 1.7e-09 37.3 0.0 1.8e-05 24.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAO84599.1 - 5.8e-08 32.1 14.3 5.8e-08 32.1 9.9 3.2 3 2 1 4 4 3 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 GAO84599.1 - 4.3e-05 22.5 4.0 4.3e-05 22.5 2.8 3.5 2 2 0 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 GAO84599.1 - 9.1e-05 21.6 0.1 0.0057 15.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAO84599.1 - 0.00012 22.0 0.1 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAO84599.1 - 0.00031 20.2 1.2 0.0024 17.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAO84599.1 - 0.00044 20.2 3.2 0.0017 18.3 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 GAO84599.1 - 0.0017 17.8 0.8 0.037 13.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO84599.1 - 0.0022 18.8 0.0 0.3 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO84599.1 - 0.012 14.8 0.0 0.3 10.2 0.0 2.8 3 1 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 GAO84599.1 - 0.015 15.6 0.1 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO84599.1 - 0.018 15.2 0.5 0.6 10.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 GAO84599.1 - 0.038 13.9 0.0 0.95 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 GAO84599.1 - 0.052 14.0 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 GAO84599.1 - 0.052 13.4 0.0 7.2 6.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 GAO84599.1 - 0.067 12.8 0.6 2.1 7.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 GAO84599.1 - 0.11 12.3 0.6 3.2 7.5 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 GAO84599.1 - 0.29 10.7 1.8 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 GAO84599.1 - 0.45 10.7 3.2 19 5.4 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAO84599.1 - 0.47 9.8 1.5 21 4.4 0.0 2.9 2 1 0 3 3 3 0 AAA-like domain DUF2207 PF09972.4 GAO84599.1 - 6.4 5.2 11.6 0.94 7.9 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.13 GAO84600.1 - 8.7e-21 73.9 1.0 1.3e-20 73.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 GAO84601.1 - 0.0043 16.4 0.2 0.0084 15.5 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Inositol_P PF00459.20 GAO84601.1 - 0.022 14.0 0.1 0.051 12.8 0.1 1.6 1 1 0 1 1 1 0 Inositol monophosphatase family Glyco_hydro_16 PF00722.16 GAO84602.1 - 1.9e-08 33.7 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TrkH PF02386.11 GAO84603.1 - 2.5e-119 397.9 14.5 8.6e-118 392.9 5.2 2.1 2 0 0 2 2 2 2 Cation transport protein Peroxidase_2 PF01328.12 GAO84604.1 - 1e-21 76.9 0.1 6.5e-21 74.3 0.0 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 DUF3632 PF12311.3 GAO84605.1 - 6.5e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Abhydrolase_6 PF12697.2 GAO84605.1 - 3.9e-24 85.8 0.3 7.6e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84605.1 - 2.6e-12 46.6 0.0 5.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO84605.1 - 7.3e-12 45.3 0.0 4.3e-10 39.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAO84605.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAO84605.1 - 0.02 14.7 0.0 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 Putative lysophospholipase DLH PF01738.13 GAO84605.1 - 0.033 13.4 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAO84605.1 - 0.035 13.5 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 GAO84605.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ribonuclease PF00545.15 GAO84606.1 - 2.6e-10 40.2 0.3 2.5e-09 37.0 0.1 2.0 1 1 1 2 2 2 1 ribonuclease Glyco_trans_2_3 PF13632.1 GAO84607.1 - 1.7e-40 138.8 6.7 3.1e-40 137.9 4.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 CN_hydrolase PF00795.17 GAO84607.1 - 2.2e-29 102.1 0.0 3.5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP-synt_ab PF00006.20 GAO84608.1 - 1.2e-114 381.2 0.1 3e-114 379.8 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_M PF01031.15 GAO84608.1 - 7.9e-106 353.1 1.0 2.4e-105 351.5 0.1 2.2 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 GAO84608.1 - 9e-57 191.5 0.1 2e-56 190.3 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAO84608.1 - 5.4e-30 103.1 5.2 5.4e-30 103.1 3.6 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain ATP-synt_ab_C PF00306.22 GAO84608.1 - 1.1e-15 58.1 0.5 4.2e-15 56.2 0.3 2.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAO84608.1 - 2.4e-15 56.5 0.6 6.1e-15 55.1 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MMR_HSR1 PF01926.18 GAO84608.1 - 0.00043 20.2 0.1 0.0027 17.6 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO84608.1 - 0.0036 17.7 0.1 0.035 14.5 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 GAO84608.1 - 0.013 15.5 0.1 9.6 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 GAO84608.1 - 0.072 12.9 0.0 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAO84608.1 - 0.074 13.0 0.0 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2236 PF09995.4 GAO84609.1 - 6.7e-43 146.7 0.7 1.1e-42 145.9 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) WD40 PF00400.27 GAO84610.1 - 7e-25 85.9 5.6 7e-07 28.8 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Mem_trans PF03547.13 GAO84610.1 - 1.9e-14 52.8 0.2 1.1e-13 50.2 0.1 2.0 1 1 0 1 1 1 1 Membrane transport protein Nup160 PF11715.3 GAO84610.1 - 0.00085 17.5 0.2 0.0015 16.7 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CLTH PF10607.4 GAO84610.1 - 0.0032 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 GAO84610.1 - 0.01 15.5 0.1 0.66 9.6 0.0 2.7 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAO84610.1 - 0.084 11.1 0.1 1.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF4221 PF13970.1 GAO84610.1 - 0.13 11.5 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) DEAD PF00270.24 GAO84611.1 - 4.2e-40 137.0 0.3 9.3e-40 135.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO84611.1 - 1.6e-29 101.5 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAO84611.1 - 0.0011 18.6 0.1 0.0028 17.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAO84611.1 - 0.014 15.0 0.4 0.032 13.8 0.3 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 GAO84611.1 - 0.018 14.9 0.1 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 GAO84611.1 - 0.025 14.3 0.3 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF1253 PF06862.7 GAO84611.1 - 0.065 11.6 0.0 0.62 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_RecD PF05127.9 GAO84611.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 GAO84611.1 - 0.079 13.1 0.7 0.37 10.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAO84611.1 - 0.085 12.4 0.3 0.12 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 GAO84612.1 - 1.6e-69 233.3 0.8 3.7e-69 232.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) DNA_ligase_A_M PF01068.16 GAO84612.1 - 5.7e-21 74.8 0.1 1.9e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain SF3a60_bindingd PF12108.3 GAO84612.1 - 4.2e-14 51.7 0.6 1.1e-13 50.4 0.4 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 GAO84612.1 - 1.4e-07 31.4 1.4 3.7e-06 26.9 0.4 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO84612.1 - 1.2e-06 28.4 2.6 1.6e-06 28.0 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DNA_ligase_A_N PF04675.9 GAO84612.1 - 1.7e-06 27.9 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus zf-C2H2_2 PF12756.2 GAO84612.1 - 0.023 14.8 0.1 0.088 12.9 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 GAO84612.1 - 0.3 10.6 7.5 28 4.4 5.2 2.8 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif APC8 PF04049.8 GAO84613.1 - 4.6e-54 182.0 0.0 9.5e-54 181.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 GAO84613.1 - 2.7e-23 80.5 4.4 0.00015 21.2 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAO84613.1 - 3e-21 74.8 12.0 3.5e-07 29.7 0.1 6.3 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 GAO84613.1 - 1.3e-19 68.4 16.1 0.059 13.3 0.0 9.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAO84613.1 - 6.6e-19 66.2 6.4 0.00031 20.3 0.0 7.5 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAO84613.1 - 6e-16 58.6 16.4 5.2e-05 23.8 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO84613.1 - 5.7e-13 48.2 13.0 0.0056 17.2 0.0 8.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAO84613.1 - 2.6e-10 40.0 23.0 0.013 15.4 0.0 7.2 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAO84613.1 - 2e-08 33.7 5.0 0.51 10.6 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84613.1 - 3.4e-08 33.7 9.5 0.07 13.4 0.1 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 GAO84613.1 - 2.8e-07 30.5 9.1 0.26 11.4 0.1 5.3 5 1 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAO84613.1 - 2.4e-06 26.9 13.5 1 9.2 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAO84613.1 - 4e-06 26.5 12.2 0.00031 20.5 0.2 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO84613.1 - 3.4e-05 24.0 26.8 0.86 10.2 0.2 9.6 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAO84613.1 - 0.00045 19.3 9.1 0.00084 18.4 2.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAO84613.1 - 2.2 8.3 16.5 17 5.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 GAO84614.1 - 7e-73 244.6 0.0 8.2e-73 244.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Arylsulfotran_2 PF14269.1 GAO84615.1 - 3.3e-63 213.6 0.8 4.6e-63 213.1 0.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO84615.1 - 1.4e-19 70.0 0.5 5.6e-19 67.9 0.4 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.16 GAO84615.1 - 0.014 14.8 0.2 2 8.0 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat NMT1 PF09084.6 GAO84616.1 - 5.5e-77 258.2 0.0 7.8e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 GAO84616.1 - 3.8e-08 33.0 1.6 0.05 12.9 0.0 3.2 2 1 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 GAO84616.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HIG_1_N PF04588.8 GAO84616.1 - 0.041 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Glycogen_syn PF05693.8 GAO84617.1 - 0 1125.3 0.0 0 1125.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 GAO84617.1 - 3.7e-07 30.4 0.2 8.2e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 GAO84617.1 - 2.2e-05 23.9 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 ADH_zinc_N_2 PF13602.1 GAO84618.1 - 1.8e-16 61.2 0.1 4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO84618.1 - 7.2e-16 57.9 0.5 1.2e-15 57.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO84618.1 - 5e-09 35.8 0.1 4.3e-06 26.4 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DUF2961 PF11175.3 GAO84618.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Vps54 PF07928.7 GAO84620.1 - 8.1e-49 165.2 0.1 2.2e-48 163.7 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 GAO84620.1 - 6.5e-06 25.2 0.9 1.5e-05 24.0 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 GAO84620.1 - 0.0032 17.0 1.8 0.0032 17.0 1.3 1.8 2 0 0 2 2 2 1 LUC7 N_terminus Chorion_S16 PF05836.7 GAO84620.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 DUF2451 PF10474.4 GAO84620.1 - 0.084 12.6 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Cytochrom_B562 PF07361.6 GAO84620.1 - 0.1 12.9 2.1 2.5 8.5 0.1 3.3 3 0 0 3 3 3 0 Cytochrome b562 MCM PF00493.18 GAO84621.1 - 4.5e-141 469.4 0.1 5.8e-141 469.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAO84621.1 - 8.3e-20 71.4 0.5 2.7e-19 69.8 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO84621.1 - 8.8e-06 25.0 0.0 0.0009 18.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO84621.1 - 4.6e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAO84621.1 - 0.00037 20.0 0.1 0.0014 18.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 GAO84621.1 - 0.027 14.8 0.2 0.1 13.0 0.2 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAO84621.1 - 0.052 13.0 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Lon_2 PF13337.1 GAO84621.1 - 0.074 11.3 0.2 0.29 9.4 0.0 1.9 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease PfkB PF00294.19 GAO84622.1 - 1.1e-35 123.3 0.1 3.1e-35 121.7 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Tau95 PF09734.4 GAO84624.1 - 2.2e-83 280.1 0.1 2.9e-83 279.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 GAO84625.1 - 3.6e-174 579.1 8.4 4.8e-174 578.7 5.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3354 PF11834.3 GAO84625.1 - 0.093 12.3 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) FAT PF02259.18 GAO84626.1 - 1.7e-72 244.3 10.0 3.3e-72 243.4 6.9 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 GAO84626.1 - 3e-30 105.4 0.2 1.1e-29 103.5 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 GAO84626.1 - 3.7e-08 32.6 0.1 1.1e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 GAO84626.1 - 0.26 11.3 4.9 1.3 9.0 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.8 GAO84627.1 - 2.2e-71 240.7 9.3 2.6e-71 240.4 6.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 GAO84627.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 GAO84627.1 - 0.04 13.5 1.8 0.081 12.5 0.2 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 GAO84627.1 - 0.16 11.5 0.8 18 4.9 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAO84627.1 - 0.28 10.7 1.3 0.69 9.4 0.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain TPR_11 PF13414.1 GAO84628.1 - 1.1e-28 98.6 17.6 4.6e-08 32.5 0.0 8.4 6 2 2 8 8 8 7 TPR repeat TPR_1 PF00515.23 GAO84628.1 - 4e-28 95.8 7.3 0.00037 19.9 0.2 10.3 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAO84628.1 - 4.5e-27 91.7 18.8 0.0012 18.5 0.0 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat Apc3 PF12895.2 GAO84628.1 - 3.7e-24 84.6 13.6 1.1e-19 70.3 0.4 5.7 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAO84628.1 - 7e-17 61.1 27.4 3.8e-08 33.1 0.1 9.5 8 2 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO84628.1 - 8.5e-16 57.0 16.7 0.22 12.2 0.3 10.6 7 3 4 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84628.1 - 9.3e-16 57.9 14.6 2.2e-05 24.6 0.0 7.8 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAO84628.1 - 3e-15 56.4 23.1 6.4e-05 23.5 0.3 8.9 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAO84628.1 - 7.3e-13 47.2 0.3 0.88 9.5 0.0 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAO84628.1 - 4.7e-10 38.8 2.7 0.28 11.4 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO84628.1 - 4.1e-08 33.1 7.4 1.8 9.1 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO84628.1 - 2.3e-06 26.9 19.4 5.1 7.1 0.1 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAO84628.1 - 6.8e-06 25.8 23.0 0.013 15.4 0.1 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat RPN7 PF10602.4 GAO84628.1 - 0.0063 15.9 0.0 4.1 6.7 0.0 3.8 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_4 PF07721.9 GAO84628.1 - 0.015 15.6 21.8 8 7.2 0.7 9.2 9 0 0 9 9 8 0 Tetratricopeptide repeat PSD1 PF07587.6 GAO84628.1 - 0.017 14.5 0.2 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) TPR_21 PF09976.4 GAO84628.1 - 0.035 14.0 5.4 1.7 8.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAO84628.1 - 0.15 11.8 20.5 15 5.4 0.0 6.9 6 2 2 8 8 7 0 Tetratricopeptide repeat p450 PF00067.17 GAO84629.1 - 1.8e-48 165.2 0.0 2.7e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_90 PF05686.7 GAO84629.1 - 7.7e-26 90.7 0.4 1.1e-25 90.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.17 GAO84630.1 - 7.4e-34 117.0 0.0 8.6e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO84631.1 - 7.1e-07 28.0 0.0 8.4e-07 27.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1707 PF08044.6 GAO84631.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Hemerythrin PF01814.18 GAO84632.1 - 7.2e-05 22.9 1.7 7.2e-05 22.9 1.2 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1136 PF06582.7 GAO84632.1 - 0.11 12.2 2.3 1.9 8.2 1.3 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) Methyltransf_2 PF00891.13 GAO84633.1 - 6.7e-45 153.1 0.0 8.6e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO84633.1 - 9.7e-07 29.3 0.1 2.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO84633.1 - 5.1e-05 23.0 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO84633.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAO84633.1 - 0.016 15.7 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAO84633.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAO84633.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 GAO84633.1 - 0.16 11.4 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) DIT1_PvcA PF05141.7 GAO84635.1 - 1e-91 307.1 0.0 1.8e-91 306.3 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 GAO84635.1 - 2.2e-27 96.3 0.0 3.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4066 PF13278.1 GAO84636.1 - 2.5e-22 78.9 0.0 7.6e-22 77.3 0.0 1.7 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO84636.1 - 3.1e-08 33.1 0.0 7e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 GAO84637.1 - 3.5e-14 52.3 2.8 8.4e-14 51.0 1.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84637.1 - 2.1e-06 27.4 12.3 3.8e-06 26.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lamp PF01299.12 GAO84637.1 - 0.84 8.7 3.7 2 7.4 2.6 1.6 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MFS_1 PF07690.11 GAO84638.1 - 1.7e-44 152.0 27.0 1.7e-44 152.0 18.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84638.1 - 2.2e-10 39.7 17.3 2.1e-09 36.5 12.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAO84638.1 - 2.5e-09 35.8 2.5 4.4e-09 35.0 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 GAO84638.1 - 0.00014 21.5 0.3 0.00047 19.8 0.2 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) DUF3611 PF12263.3 GAO84638.1 - 1.1 8.5 6.1 0.14 11.5 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Herpes_US9 PF06072.6 GAO84638.1 - 1.6 8.5 4.4 3.3 7.6 0.6 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 GATase_5 PF13507.1 GAO84639.1 - 2.2e-97 325.0 0.0 3.5e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 GAO84639.1 - 1.9e-43 148.1 0.2 1.3e-21 77.2 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAO84639.1 - 1.7e-25 89.0 0.1 2.1e-24 85.6 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Spc97_Spc98 PF04130.8 GAO84640.1 - 1.9e-83 280.6 7.8 1.9e-83 280.6 5.4 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 GAO84640.1 - 3.6e-11 41.9 0.1 5.8e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 BTV_NS2 PF04514.7 GAO84640.1 - 0.0091 14.9 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 FANCI_S1-cap PF14674.1 GAO84640.1 - 0.11 12.5 0.4 0.4 10.7 0.3 1.9 1 0 0 1 1 1 0 FANCI solenoid 1 cap PBP1_TM PF14812.1 GAO84640.1 - 1.9 8.8 9.2 4.8 7.5 6.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_15 PF01793.11 GAO84641.1 - 2.1e-135 450.9 7.9 2.5e-135 450.7 5.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.11 GAO84642.1 - 1.9e-39 133.9 0.3 2.6e-39 133.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.4 GAO84642.1 - 0.052 13.3 0.1 9.7 5.9 0.0 2.2 1 1 1 2 2 2 0 Tumour suppressor protein ELO PF01151.13 GAO84643.1 - 5.1e-61 206.1 22.5 6e-61 205.9 15.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.7 GAO84643.1 - 3.3 7.9 8.6 2.8 8.2 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) Wbp11 PF09429.5 GAO84644.1 - 0.043 13.8 0.4 0.093 12.7 0.3 1.5 1 0 0 1 1 1 0 WW domain binding protein 11 PNTB PF02233.11 GAO84645.1 - 6e-170 565.9 22.3 1.1e-169 565.0 15.4 1.5 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 GAO84645.1 - 7e-52 175.3 0.9 1.2e-51 174.5 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 GAO84645.1 - 4.6e-47 159.4 0.3 1.2e-46 158.0 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 GAO84645.1 - 3.9e-31 107.0 4.5 3.9e-31 107.0 3.1 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 GAO84645.1 - 0.00054 19.1 0.1 1.2 8.2 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 GAO84645.1 - 0.0056 17.2 0.0 0.033 14.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84645.1 - 0.024 14.2 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TPP_enzyme_M PF00205.17 GAO84645.1 - 0.035 13.8 0.2 0.14 11.9 0.2 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 GAO84645.1 - 0.096 12.5 1.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 GAO84645.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 GAO84645.1 - 3 7.9 7.8 7.9 6.5 0.0 3.7 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 GAO84645.1 - 5.7 7.0 10.3 0.23 11.5 0.9 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain AA_permease_2 PF13520.1 GAO84647.1 - 3.3e-41 141.2 46.2 4.4e-41 140.8 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO84647.1 - 4.6e-19 68.1 37.8 6.4e-19 67.6 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1029 PF06269.7 GAO84647.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1029) Fungal_trans_2 PF11951.3 GAO84648.1 - 1.7e-39 135.5 0.1 2.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cas_CXXC_CXXC PF09706.5 GAO84649.1 - 0.13 12.4 0.1 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Sugar_tr PF00083.19 GAO84650.1 - 4.3e-80 269.4 22.7 4.9e-80 269.2 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84650.1 - 2.5e-24 85.6 46.1 2.1e-20 72.7 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HD_4 PF13328.1 GAO84650.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 HD domain Cyclase PF04199.8 GAO84651.1 - 1.6e-12 47.4 0.8 2.7e-12 46.7 0.4 1.5 1 1 1 2 2 2 1 Putative cyclase adh_short_C2 PF13561.1 GAO84653.1 - 6.4e-34 117.7 0.0 8.1e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO84653.1 - 9.4e-30 103.7 0.1 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84653.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO84653.1 - 0.00045 19.7 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO84653.1 - 0.074 12.8 0.4 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 GAO84654.1 - 7.4e-12 44.6 0.4 6.8e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84654.1 - 1.1e-08 34.8 13.1 2.3e-08 33.8 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_32 PF13679.1 GAO84655.1 - 7.5e-21 74.2 0.5 3.1e-20 72.3 0.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 GAO84657.1 - 1e-24 86.7 0.9 3.8e-24 84.9 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAO84657.1 - 7.1e-15 54.4 10.4 1.1e-14 53.8 2.4 2.8 3 0 0 3 3 3 1 SNARE domain TPR_MLP1_2 PF07926.7 GAO84657.1 - 0.035 13.8 0.9 0.36 10.5 0.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 GAO84657.1 - 0.037 13.2 0.5 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein THOC7 PF05615.8 GAO84657.1 - 0.04 14.1 1.9 0.55 10.4 0.2 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 DUF812 PF05667.6 GAO84657.1 - 0.064 11.7 2.7 0.68 8.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) IncA PF04156.9 GAO84657.1 - 0.066 12.7 0.1 0.066 12.7 0.0 3.0 3 0 0 3 3 2 0 IncA protein Laminin_II PF06009.7 GAO84657.1 - 0.075 12.7 1.3 7.1 6.3 0.0 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF3584 PF12128.3 GAO84657.1 - 0.096 10.0 2.7 0.43 7.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF883 PF05957.8 GAO84657.1 - 0.11 12.8 4.5 4 7.9 0.0 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) TBPIP PF07106.8 GAO84657.1 - 0.2 11.1 4.4 0.51 9.8 0.4 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 GAO84657.1 - 0.34 11.1 6.1 17 5.7 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 GAO84657.1 - 0.8 10.0 3.1 4.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 GAO84657.1 - 1.3 6.7 8.1 0.27 8.9 1.2 2.0 2 0 0 2 2 2 0 Myosin tail SlyX PF04102.7 GAO84657.1 - 5 7.5 8.9 84 3.6 0.0 3.6 3 1 0 3 3 3 0 SlyX FlaC_arch PF05377.6 GAO84657.1 - 7.8 6.4 7.4 15 5.6 0.0 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) NAP PF00956.13 GAO84658.1 - 2.5e-41 141.4 14.9 2.5e-41 141.4 10.3 1.8 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) NmrA PF05368.8 GAO84659.1 - 3.1e-70 236.0 0.0 3.8e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO84659.1 - 8.1e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Asparaginase PF00710.15 GAO84660.1 - 5.7e-106 353.9 0.0 7.5e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 GAO84660.1 - 1.4e-08 34.9 0.0 7e-08 32.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84660.1 - 1.8e-06 27.4 0.3 0.089 12.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAO84660.1 - 1.3e-05 25.5 0.0 0.0019 18.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO84660.1 - 0.00011 22.3 0.5 0.0056 16.9 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) MTTB PF06253.6 GAO84660.1 - 0.036 11.8 0.2 0.052 11.3 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) AA_permease_2 PF13520.1 GAO84661.1 - 8.2e-51 172.8 49.1 9.5e-51 172.6 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO84661.1 - 1.9e-26 92.4 39.8 2.5e-26 92.0 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1996 PF09362.5 GAO84662.1 - 9.7e-80 267.6 0.2 1.5e-79 266.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tape_meas_lam_C PF09718.5 GAO84662.1 - 0.014 15.3 0.8 0.13 12.2 0.8 2.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) LCCL PF03815.14 GAO84664.1 - 1.8e-25 88.7 0.2 2.9e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 GAO84665.1 - 1.2e-07 31.0 0.0 5.8e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II UPF0029 PF01205.14 GAO84666.1 - 3.3e-30 104.0 0.3 5.4e-30 103.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 GAO84666.1 - 3.3e-08 33.4 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Glyco_hydro_61 PF03443.9 GAO84667.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.1 GAO84667.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Ribosomal_L4 PF00573.17 GAO84668.1 - 1.5e-42 145.2 0.9 2.1e-42 144.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 GAO84668.1 - 1.2e-30 105.1 2.6 1.2e-30 105.1 1.8 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Fungal_trans PF04082.13 GAO84669.1 - 2.5e-10 39.6 0.5 4.3e-10 38.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO84669.1 - 3.3e-07 30.0 11.5 6.6e-07 29.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 GAO84670.1 - 2e-47 160.6 3.0 2.1e-47 160.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 GAO84670.1 - 7.9e-18 63.9 0.9 1.7e-17 62.9 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4230 PF14014.1 GAO84670.1 - 0.22 11.3 2.2 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) SKIP_SNW PF02731.10 GAO84671.1 - 4.2e-68 227.7 4.4 4.2e-68 227.7 3.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 GAO84671.1 - 1.8 8.2 10.2 3.5 7.2 7.1 1.5 1 0 0 1 1 1 0 Protein Family FAM60A ACT_7 PF13840.1 GAO84672.1 - 1.1e-25 88.9 0.4 7.3e-17 60.6 0.0 3.3 3 0 0 3 3 3 3 ACT domain WD40 PF00400.27 GAO84673.1 - 2.5e-34 115.9 11.9 1.2e-06 28.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 GAO84673.1 - 0.026 14.0 2.0 0.3 10.4 1.4 2.4 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.16 GAO84673.1 - 0.036 13.6 0.3 0.38 10.3 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat VID27 PF08553.5 GAO84673.1 - 0.18 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein SnoaL_2 PF12680.2 GAO84673.1 - 0.39 11.1 2.9 10 6.5 0.0 2.9 1 1 1 2 2 2 0 SnoaL-like domain Septin PF00735.13 GAO84674.1 - 1.8e-115 384.8 0.6 1.8e-115 384.8 0.4 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAO84674.1 - 3.8e-07 30.0 0.0 7.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO84674.1 - 4.2e-07 29.5 0.2 1.7e-05 24.3 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAO84674.1 - 1.3e-05 24.4 0.0 3.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO84674.1 - 0.0018 18.4 0.1 0.0068 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAO84674.1 - 0.0033 17.0 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAO84674.1 - 0.005 17.3 0.0 0.017 15.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAO84674.1 - 0.0075 15.7 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 GAO84674.1 - 0.0083 15.2 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 AIG1 family IIGP PF05049.8 GAO84674.1 - 0.0089 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 GAO84674.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.22 GAO84674.1 - 0.024 14.9 0.2 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 GAO84674.1 - 0.039 12.8 0.4 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 GAO84674.1 - 0.039 13.3 0.9 0.12 11.7 0.3 2.1 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 GAO84674.1 - 0.041 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 GAO84674.1 - 0.072 12.7 0.1 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 GAO84674.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.4 GAO84674.1 - 0.076 12.5 0.8 2.7 7.4 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 GAO84674.1 - 0.08 12.9 1.0 0.49 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 GAO84674.1 - 0.085 12.6 6.6 0.96 9.2 0.1 3.0 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 GAO84674.1 - 0.12 11.8 1.0 9.5 5.6 0.1 2.8 1 1 1 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 GAO84674.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 GAO84674.1 - 0.25 10.2 4.1 0.62 9.0 2.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Myc-LZ PF02344.10 GAO84674.1 - 0.7 9.5 5.1 0.96 9.1 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 GAO84674.1 - 4.5 7.5 17.8 80 3.4 12.3 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 GAO84675.1 - 1.6e-48 160.8 28.0 1.3e-12 47.0 0.1 12.3 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.7 GAO84675.1 - 1.3e-30 105.5 0.0 2.2e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 GAO84675.1 - 3.8e-07 30.0 1.3 0.029 14.0 0.1 6.1 5 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAO84675.1 - 4.6e-06 25.0 6.5 0.66 8.0 0.1 5.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Gmad1 PF10647.4 GAO84675.1 - 1.9e-05 24.2 0.3 0.0049 16.2 0.0 3.1 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 GAO84675.1 - 0.024 13.7 0.1 8.8 5.3 0.0 2.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 GAO84675.1 - 0.027 12.3 0.1 6.6 4.4 0.0 2.9 2 1 0 2 2 2 0 IKI3 family DUF1513 PF07433.6 GAO84675.1 - 0.052 12.4 0.2 2.4 6.9 0.0 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF1513) p450 PF00067.17 GAO84676.1 - 3.5e-30 104.9 0.3 4.6e-30 104.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 XRN_N PF03159.13 GAO84677.1 - 2.7e-102 341.2 1.3 4.2e-102 340.5 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Cyclase PF04199.8 GAO84677.1 - 2.3e-13 50.1 0.0 4.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase DUF3480 PF11979.3 GAO84677.1 - 0.26 9.8 0.2 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) WD40 PF00400.27 GAO84678.1 - 1.2e-43 145.4 4.9 5.5e-09 35.5 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAO84678.1 - 1.1e-29 102.0 0.8 2.3e-29 101.0 0.6 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 GAO84678.1 - 0.0011 17.8 0.4 0.17 10.6 0.5 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 GAO84678.1 - 0.009 14.1 3.2 1.5 6.8 0.1 3.7 2 1 2 5 5 5 2 Nucleoporin Nup120/160 SGL PF08450.7 GAO84678.1 - 0.089 12.1 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region GTP_cyclohydroI PF01227.17 GAO84679.1 - 4.5e-72 241.0 0.2 6.9e-72 240.4 0.2 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I F-box PF00646.28 GAO84679.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain QueF PF14489.1 GAO84679.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein F-box-like PF12937.2 GAO84679.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 GAO84680.1 - 1.1e-68 231.2 0.0 1.8e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain IF4E PF01652.13 GAO84680.1 - 4.1e-51 172.7 0.1 1e-50 171.5 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Pkinase_Tyr PF07714.12 GAO84680.1 - 1.3e-34 119.5 0.0 2.4e-34 118.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO84680.1 - 0.00013 21.0 0.0 0.00086 18.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAO84680.1 - 0.026 13.6 0.1 0.06 12.4 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C48 PF02902.14 GAO84681.1 - 6.2e-32 110.9 0.0 2.1e-31 109.2 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2 PF06094.7 GAO84682.1 - 8.3e-13 48.7 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family SPC22 PF04573.7 GAO84683.1 - 2.4e-35 121.3 0.2 1.2e-24 86.5 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit BCDHK_Adom3 PF10436.4 GAO84684.1 - 1.1e-46 158.3 0.1 2.1e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAO84684.1 - 6.3e-10 38.7 0.0 3.4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 GAO84684.1 - 0.017 14.9 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 GAO84684.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 GAO84685.1 - 6.1e-89 297.5 0.3 1.7e-88 296.0 0.1 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 GAO84685.1 - 2.9e-70 236.0 2.9 1e-68 230.9 0.3 3.3 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 GAO84685.1 - 1.1e-56 191.9 0.3 1.1e-56 191.9 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO84685.1 - 1.5e-33 116.4 0.0 9.4e-33 113.9 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 GAO84685.1 - 2.7e-08 34.0 0.1 1.6e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 GAO84685.1 - 0.044 13.4 0.9 2.2 8.0 0.1 3.9 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 GAO84686.1 - 3.7e-47 160.4 1.4 4.3e-47 160.2 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hydrophobin PF01185.13 GAO84688.1 - 9e-05 22.8 3.4 0.00015 22.1 2.4 1.4 1 0 0 1 1 1 1 Fungal hydrophobin CTD_bind PF04818.8 GAO84689.1 - 0.00056 20.0 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PAT1 PF09770.4 GAO84689.1 - 0.25 9.5 21.8 0.37 8.9 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1777 PF08648.7 GAO84689.1 - 2.2 7.9 34.4 4.2 7.0 23.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RAP1 PF07218.6 GAO84689.1 - 4.5 5.2 5.0 6.2 4.7 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SpaB_C PF14028.1 GAO84690.1 - 0.12 11.9 3.7 0.14 11.6 2.6 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Helicase_C_3 PF13625.1 GAO84691.1 - 6.5e-26 90.5 0.0 1.8e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO84691.1 - 2.7e-14 53.4 0.0 5.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAO84691.1 - 2.2e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO84691.1 - 9.9e-12 44.2 0.1 1.6e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 GAO84691.1 - 2.2e-06 27.2 0.0 5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 GAO84691.1 - 0.0037 16.0 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4243 PF14027.1 GAO84692.1 - 8.6e-112 373.8 0.1 1e-111 373.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Gag_p24 PF00607.15 GAO84692.1 - 0.12 11.8 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) CN_hydrolase PF00795.17 GAO84694.1 - 1.1e-30 106.4 0.0 1.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 GAO84694.1 - 1.5e-19 69.9 0.0 9.4e-19 67.2 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 GAO84694.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase NUDIX-like PF09296.6 GAO84695.1 - 9.9e-27 93.1 0.0 2.7e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 GAO84695.1 - 3.2e-15 55.9 0.1 6.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 GAO84695.1 - 4.3e-06 26.1 0.4 8.1e-06 25.2 0.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain POT1 PF02765.12 GAO84696.1 - 3.9e-18 65.7 0.0 6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 GAO84697.1 - 3.6e-45 154.1 0.2 6e-28 97.3 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAO84697.1 - 3.4e-19 69.7 0.0 1.7e-18 67.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO84697.1 - 3.5e-14 52.8 0.0 5e-11 42.6 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAO84697.1 - 4.3e-14 52.1 0.4 4.6e-11 42.2 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO84697.1 - 1.1e-10 41.7 0.0 2e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO84697.1 - 2.2e-05 24.3 0.0 5.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO84697.1 - 4.4e-05 22.6 0.2 0.00039 19.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAO84697.1 - 0.029 13.2 0.0 3.4 6.4 0.1 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO84697.1 - 0.092 13.1 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HDA2-3 PF11496.3 GAO84698.1 - 5.7e-67 225.6 0.1 1.1e-66 224.6 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF3037 PF11236.3 GAO84698.1 - 0.0045 17.0 2.2 0.053 13.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3037) Fez1 PF06818.10 GAO84698.1 - 0.26 11.2 37.4 0.31 11.0 7.8 2.9 1 1 1 2 2 2 0 Fez1 Transglut_core PF01841.14 GAO84699.1 - 1e-10 41.7 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 GAO84699.1 - 4e-09 35.8 0.1 9.7e-09 34.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO84699.1 - 2.7e-07 29.8 0.0 7.3e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO84699.1 - 3.3e-06 26.5 0.1 1e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain DHHA2 PF02833.9 GAO84700.1 - 1.5e-17 63.9 0.0 2.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 GAO84700.1 - 3.9e-05 23.3 0.0 0.00053 19.6 0.0 2.2 1 1 0 1 1 1 1 DHH family PALP PF00291.20 GAO84701.1 - 2.3e-23 82.9 0.0 3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PLU-1 PF08429.6 GAO84702.1 - 1.1e-106 356.5 19.6 4.1e-104 348.0 13.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 GAO84702.1 - 6.8e-44 148.7 0.3 1.9e-43 147.3 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 GAO84702.1 - 1.6e-27 95.2 0.1 5.5e-27 93.4 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 GAO84702.1 - 1.4e-18 66.6 6.0 4.7e-18 64.9 4.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 GAO84702.1 - 4e-18 64.6 1.6 9.7e-18 63.3 1.1 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 GAO84702.1 - 2.5e-17 62.2 32.1 4.4e-10 39.1 4.4 3.5 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.1 GAO84702.1 - 5e-05 22.9 2.0 5e-05 22.9 1.4 3.6 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 GAO84702.1 - 0.0034 16.6 7.9 0.053 12.8 0.5 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.1 GAO84702.1 - 0.61 9.9 22.9 2.4 8.0 5.2 2.8 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.17 GAO84702.1 - 1.2 8.8 20.1 0.37 10.5 0.2 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 GAO84702.1 - 4.6 7.3 10.2 1.3 9.1 2.9 2.8 2 0 0 2 2 2 0 C1-like domain Spore_III_AB PF09548.5 GAO84702.1 - 7.8 6.2 5.6 6.7 6.4 1.1 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GIY-YIG PF01541.19 GAO84703.1 - 7.8e-08 32.5 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 GAO84703.1 - 0.00063 19.6 8.1 0.0014 18.5 5.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain Thymidylate_kin PF02223.12 GAO84704.1 - 4e-46 156.7 0.0 4.6e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 GAO84704.1 - 0.00061 19.0 0.1 0.0016 17.6 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Rad60-SLD PF11976.3 GAO84704.1 - 0.008 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Resolvase PF00239.16 GAO84704.1 - 0.019 14.8 0.1 0.058 13.2 0.0 1.9 2 0 0 2 2 2 0 Resolvase, N terminal domain AAA_33 PF13671.1 GAO84704.1 - 0.021 14.7 0.0 0.032 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO84704.1 - 0.092 12.7 0.1 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAO84704.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TGT PF01702.13 GAO84705.1 - 2.7e-46 157.7 0.0 3.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.12 GAO84706.1 - 9e-102 340.0 0.0 1.3e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.4 GAO84707.1 - 8.8e-26 89.7 0.0 1.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 GAO84707.1 - 0.0022 18.2 0.4 0.0028 17.9 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 GAO84708.1 - 1.3e-55 186.8 0.0 1.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 GAO84709.1 - 9.1e-148 492.7 6.3 1.2e-147 492.3 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO84709.1 - 3.1e-24 84.6 0.6 8e-24 83.2 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like PQ-loop PF04193.9 GAO84710.1 - 1.4e-15 56.5 0.1 1.4e-15 56.5 0.0 2.9 4 0 0 4 4 4 1 PQ loop repeat Glyco_hydro_18 PF00704.23 GAO84710.1 - 1.5e-15 57.4 2.2 6.3e-15 55.4 0.3 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 NMT1 PF09084.6 GAO84710.1 - 0.001 18.6 0.0 0.007 15.9 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Pyr_redox_2 PF07992.9 GAO84711.1 - 9.8e-17 61.4 0.0 1.2e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO84711.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAO84711.1 - 0.0016 17.4 0.0 0.25 10.1 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAO84711.1 - 0.0024 16.9 0.2 0.0091 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAO84711.1 - 0.003 16.1 0.0 0.0085 14.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 GAO84711.1 - 0.0036 17.0 0.3 0.46 10.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO84711.1 - 0.0063 16.6 0.2 0.75 9.8 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO84711.1 - 0.012 14.5 0.0 0.014 14.3 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAO84711.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 GAO84711.1 - 0.079 11.8 0.1 0.35 9.6 0.0 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A E1-E2_ATPase PF00122.15 GAO84712.1 - 6.8e-76 254.3 1.4 7.6e-75 250.8 0.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAO84712.1 - 1.4e-24 87.6 0.0 4e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO84712.1 - 2.7e-13 50.5 0.0 5.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO84712.1 - 6e-07 28.8 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAO84712.1 - 0.0021 17.9 0.0 0.006 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO84712.1 - 0.0023 17.5 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.16 GAO84713.1 - 4e-102 341.0 0.0 5.7e-102 340.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAO84713.1 - 5.7e-40 136.8 0.1 1e-39 136.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 GAO84713.1 - 1.1e-06 28.9 0.4 3.9e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO84713.1 - 0.021 14.7 0.0 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 GAO84713.1 - 0.14 11.2 0.7 0.39 9.7 0.5 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 GAO84714.1 - 2.6e-30 105.4 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 GAO84715.1 - 1.3e-35 122.1 1.7 2.2e-35 121.4 1.1 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 GAO84715.1 - 1.1e-06 28.3 0.1 4.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 GAO84715.1 - 2.8e-05 24.0 3.2 0.00018 21.4 0.5 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 GAO84715.1 - 0.0034 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Reo_sigmaC PF04582.7 GAO84715.1 - 0.0039 16.4 0.2 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein EzrA PF06160.7 GAO84715.1 - 0.0083 14.3 0.4 0.011 13.9 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.6 GAO84715.1 - 0.012 14.2 1.5 0.019 13.6 1.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein VWA_CoxE PF05762.9 GAO84715.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF3287 PF11690.3 GAO84715.1 - 0.023 14.7 0.1 0.098 12.7 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.6 GAO84715.1 - 0.047 13.5 2.7 5.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Bul1_C PF04426.7 GAO84715.1 - 0.048 12.8 0.1 0.087 12.0 0.0 1.6 2 0 0 2 2 2 0 Bul1 C terminus VWA PF00092.23 GAO84715.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain ING PF12998.2 GAO84715.1 - 0.13 12.5 2.0 0.21 11.8 0.6 1.9 2 1 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding Mst1_SARAH PF11629.3 GAO84715.1 - 0.18 11.6 2.8 0.15 11.9 0.4 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Dor1 PF04124.7 GAO84715.1 - 0.21 10.0 3.6 0.34 9.3 2.5 1.4 1 0 0 1 1 1 0 Dor1-like family TBPIP PF07106.8 GAO84715.1 - 0.8 9.2 5.6 3.2 7.2 0.7 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_14 PF13428.1 GAO84716.1 - 0.075 13.6 0.3 0.21 12.3 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ParA PF10609.4 GAO84717.1 - 1.6e-33 114.4 0.0 2.7e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAO84717.1 - 5.9e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 GAO84717.1 - 1.6e-06 27.4 0.0 1.1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 GAO84717.1 - 1.4e-05 25.1 0.0 4.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAO84717.1 - 0.00015 20.9 0.7 0.00015 20.9 0.5 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 GAO84717.1 - 0.00048 19.5 0.1 0.00082 18.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 GAO84717.1 - 0.0025 17.2 0.4 0.0062 15.9 0.2 1.8 1 1 0 1 1 1 1 YhjQ protein ArgK PF03308.11 GAO84717.1 - 0.0078 15.0 0.3 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 GAO84717.1 - 0.03 13.9 0.1 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 GAO84717.1 - 0.069 12.8 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UIM PF02809.15 GAO84717.1 - 0.16 11.6 0.3 0.16 11.6 0.2 1.9 2 0 0 2 2 1 0 Ubiquitin interaction motif DUF258 PF03193.11 GAO84717.1 - 0.3 10.2 1.3 0.6 9.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SEP PF08059.8 GAO84718.1 - 8.1e-28 96.5 0.1 2e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 GAO84718.1 - 1e-14 54.3 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 GAO84718.1 - 1.5e-13 49.9 0.8 2.5e-13 49.2 0.6 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 GAO84718.1 - 0.057 13.2 0.2 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 UBA/TS-N domain TOM13 PF08219.6 GAO84719.1 - 4.1e-31 106.5 0.0 5.2e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Sialidase_penC PF12135.3 GAO84719.1 - 0.05 13.2 0.2 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain 60KD_IMP PF02096.15 GAO84720.1 - 2e-37 128.7 0.3 3.1e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ADK PF00406.17 GAO84721.1 - 4.8e-10 39.5 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 GAO84721.1 - 7.3e-08 33.2 0.0 1.4e-07 32.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO84721.1 - 1.3e-07 31.5 0.0 5.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO84721.1 - 0.0003 21.1 0.0 0.0056 16.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO84721.1 - 0.00088 18.7 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAO84721.1 - 0.00092 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 GAO84721.1 - 0.0081 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAO84721.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAO84721.1 - 0.017 14.8 0.1 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KTI12 PF08433.5 GAO84721.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.7 GAO84721.1 - 0.049 12.6 0.0 0.083 11.9 0.0 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAO84721.1 - 0.084 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain TAFII28 PF04719.9 GAO84722.1 - 1e-18 66.8 0.1 2.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region SRP-alpha_N PF04086.8 GAO84722.1 - 0.1 11.9 3.6 0.053 12.8 0.2 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.4 GAO84722.1 - 1.2 7.3 13.2 0.079 11.2 5.9 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAM_decarbox PF01536.11 GAO84723.1 - 7.3e-88 294.4 0.0 1.2e-86 290.4 0.0 2.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 GAO84724.1 - 1.1e-34 118.4 0.0 3e-34 116.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 GAO84724.1 - 7.7e-24 83.4 0.3 1.9e-23 82.1 0.1 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 GAO84724.1 - 0.00019 21.4 0.3 0.00092 19.2 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAO84724.1 - 0.013 15.5 0.3 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.15 GAO84725.1 - 5.8e-16 58.3 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO84725.1 - 3.2e-05 23.9 0.0 8.2e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF605 PF04652.11 GAO84725.1 - 0.0076 15.6 24.8 0.023 14.1 1.0 2.1 2 0 0 2 2 2 2 Vta1 like IPP-2 PF04979.9 GAO84726.1 - 1.4e-10 41.4 13.3 2.5e-06 27.7 1.2 2.5 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.3 GAO84726.1 - 0.034 13.7 0.3 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) CAF1A PF12253.3 GAO84727.1 - 2.1e-26 91.8 6.2 2.1e-26 91.8 4.3 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 GAO84727.1 - 3.5e-05 23.3 71.5 3.5e-05 23.3 49.5 3.4 1 1 1 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 GAO84727.1 - 0.28 10.3 42.8 0.73 8.9 29.7 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 GAO84727.1 - 0.77 8.1 47.9 3.4 6.0 33.5 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 GAO84727.1 - 9.5 5.9 30.8 29 4.4 21.4 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CoA_transf_3 PF02515.12 GAO84729.1 - 4.2e-52 176.1 0.0 5.7e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III WW PF00397.21 GAO84730.1 - 7.7e-10 38.4 4.7 2.1e-09 37.0 3.2 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 GAO84730.1 - 0.0071 16.4 8.1 0.011 15.8 5.6 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Phasin PF05597.6 GAO84730.1 - 0.12 12.1 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Glyco_hydro_18 PF00704.23 GAO84731.1 - 3.3e-18 66.2 0.5 1.1e-17 64.5 0.0 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF3100 PF11299.3 GAO84731.1 - 0.076 12.2 6.0 0.16 11.1 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) Abhydrolase_3 PF07859.8 GAO84732.1 - 4.7e-66 222.3 0.0 5.9e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84732.1 - 9.8e-11 41.2 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 GAO84732.1 - 8.5e-07 28.0 0.1 1.5e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAO84732.1 - 0.018 13.6 0.0 0.038 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) FLgD_tudor PF13861.1 GAO84732.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 FlgD Tudor-like domain Ribonuc_L-PSP PF01042.16 GAO84733.1 - 5.6e-40 135.8 0.1 6.1e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 GAO84733.1 - 0.026 14.0 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Cu-oxidase_2 PF07731.9 GAO84734.1 - 1e-44 151.3 11.9 1.8e-42 144.1 1.2 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAO84734.1 - 8e-44 148.1 8.7 1.6e-40 137.5 1.2 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO84734.1 - 6.8e-43 146.3 5.9 9.2e-38 129.6 0.6 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 GAO84734.1 - 0.00019 21.2 0.0 0.22 11.4 0.0 3.6 2 1 0 2 2 2 1 Cupredoxin-like domain FTR1 PF03239.9 GAO84735.1 - 4.8e-69 232.6 4.3 5.5e-69 232.4 3.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Trep_Strep PF09605.5 GAO84735.1 - 0.73 9.4 7.0 4.2 7.0 2.8 2.3 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF904 PF06005.7 GAO84737.1 - 0.00047 20.3 5.9 0.00047 20.3 4.1 8.1 4 2 1 5 5 5 1 Protein of unknown function (DUF904) BRE1 PF08647.6 GAO84737.1 - 0.001 18.9 1.0 0.001 18.9 0.7 6.8 5 2 1 6 6 6 1 BRE1 E3 ubiquitin ligase Metal_resist PF13801.1 GAO84737.1 - 0.0019 18.1 4.5 0.0019 18.1 3.1 6.6 4 2 1 7 7 7 1 Heavy-metal resistance Fib_alpha PF08702.5 GAO84737.1 - 0.0052 16.9 1.4 0.0052 16.9 0.9 6.4 3 3 3 6 6 6 2 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 GAO84737.1 - 0.0054 16.1 12.2 0.0054 16.1 8.5 6.9 3 2 2 6 6 6 2 Phage minor structural protein GP20 ATG16 PF08614.6 GAO84737.1 - 0.01 15.7 89.1 0.093 12.5 18.3 5.0 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 GAO84737.1 - 0.032 13.4 30.2 0.27 10.3 1.2 4.3 2 1 1 4 4 4 0 Reovirus sigma C capsid protein DUF869 PF05911.6 GAO84737.1 - 0.053 11.7 61.1 0.41 8.8 21.8 3.0 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 GAO84737.1 - 0.47 9.8 73.5 0.27 10.6 5.4 4.4 3 1 0 3 3 3 0 Intermediate filament protein DUF4279 PF14106.1 GAO84737.1 - 0.79 9.6 10.2 2.7 7.8 0.6 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4279) KGG PF10685.4 GAO84738.1 - 1.2e-18 66.4 10.6 1.8e-09 37.2 0.1 3.3 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif adh_short PF00106.20 GAO84739.1 - 3.8e-29 101.7 1.9 5.1e-29 101.3 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84739.1 - 5.2e-29 101.7 0.0 6.3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84739.1 - 6.2e-17 61.8 1.5 9.1e-17 61.2 1.0 1.1 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 GAO84739.1 - 0.032 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO84739.1 - 0.11 12.5 0.1 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.23 GAO84740.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Cellulase-like PF12876.2 GAO84740.1 - 0.064 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_85 PF03644.8 GAO84740.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 PhoD PF09423.5 GAO84741.1 - 7.9e-64 215.8 0.0 1.1e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 GAO84742.1 - 1.3e-74 249.9 3.5 2e-74 249.2 2.5 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 GAO84742.1 - 8e-24 83.8 0.2 8e-24 83.8 0.1 4.1 5 1 0 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 GAO84742.1 - 9e-18 64.1 0.4 2e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 GAO84742.1 - 3.2e-09 36.4 0.2 8.8e-09 35.0 0.2 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO84742.1 - 1.6e-07 31.3 0.3 2.1e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAO84742.1 - 2.8e-05 24.9 0.0 6.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAO84742.1 - 5e-05 23.0 0.1 0.00014 21.5 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 GAO84742.1 - 6.6e-05 22.8 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain CbiA PF01656.18 GAO84742.1 - 0.00015 21.1 0.4 0.00051 19.4 0.3 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 GAO84742.1 - 0.00067 18.5 1.9 0.0012 17.6 0.1 2.4 2 1 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 GAO84742.1 - 0.00083 19.0 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 GAO84742.1 - 0.0011 18.1 0.1 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.5 GAO84742.1 - 0.0016 17.7 1.1 1 8.5 0.8 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 GAO84742.1 - 0.0018 18.3 0.1 0.0056 16.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO84742.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO84742.1 - 0.0051 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 GAO84742.1 - 0.0067 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 GAO84742.1 - 0.0075 15.8 0.6 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 GAO84742.1 - 0.01 15.7 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAO84742.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Thymidylate_kin PF02223.12 GAO84742.1 - 0.014 14.7 0.1 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase Arf PF00025.16 GAO84742.1 - 0.11 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.7 GAO84743.1 - 3.4e-37 127.4 6.6 3.4e-37 127.4 4.6 2.5 2 1 0 2 2 2 1 Rrp15p MMR_HSR1_C PF08438.5 GAO84743.1 - 0.14 12.3 1.2 4.8 7.4 0.1 2.8 1 1 1 2 2 2 0 GTPase of unknown function C-terminal Fer2 PF00111.22 GAO84744.1 - 1e-14 53.9 0.7 1.4e-14 53.5 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Phage_base_V PF04717.7 GAO84744.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage-related baseplate assembly protein Mito_carr PF00153.22 GAO84745.1 - 2.1e-10 40.1 3.0 0.15 11.8 0.0 5.3 4 1 0 4 4 4 4 Mitochondrial carrier protein Hap4_Hap_bind PF10297.4 GAO84746.1 - 4.9e-09 35.7 7.1 4.9e-09 35.7 4.9 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 GAO84746.1 - 1.3e-07 31.4 11.5 5.9e-06 26.1 7.9 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAO84746.1 - 0.0012 18.6 4.7 0.0032 17.2 3.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF2408 PF10303.4 GAO84746.1 - 0.0043 17.1 0.3 0.0073 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) SPX PF03105.14 GAO84746.1 - 0.044 13.5 2.3 0.064 13.0 1.6 1.3 1 0 0 1 1 1 0 SPX domain Phage_int_SAM_5 PF13102.1 GAO84746.1 - 0.049 13.6 0.5 0.097 12.6 0.3 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain FlaC_arch PF05377.6 GAO84746.1 - 0.067 13.0 1.5 0.13 12.1 1.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 GAO84746.1 - 0.068 12.8 3.8 0.11 12.1 2.7 1.3 1 0 0 1 1 1 0 Mnd1 family Tup_N PF08581.5 GAO84746.1 - 0.092 12.9 2.2 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Tup N-terminal Phlebovirus_NSM PF07246.6 GAO84746.1 - 0.27 10.3 2.7 0.45 9.6 1.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ADH_N PF08240.7 GAO84747.1 - 1.2e-28 98.9 1.5 3.2e-28 97.6 1.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 GAO84747.1 - 9.9e-06 25.1 0.3 2.2e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 GAO84747.1 - 0.012 15.1 0.2 3 7.4 0.0 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Glyco_hydro_71 PF03659.9 GAO84748.1 - 1.3e-156 520.9 0.1 1.5e-156 520.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Peptidase_M18 PF02127.10 GAO84749.1 - 2.5e-133 444.7 0.0 2.8e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) NOB1_Zn_bind PF08772.6 GAO84750.1 - 2.9e-32 110.2 5.2 5e-32 109.5 3.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 GAO84750.1 - 0.043 13.7 10.5 0.35 10.8 7.3 2.4 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator Nop10p PF04135.7 GAO84751.1 - 1.6e-20 72.5 0.1 2.1e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PBCV_basic_adap PF08789.5 GAO84751.1 - 0.071 12.7 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain tRNA_int_endo PF01974.12 GAO84752.1 - 2.1e-21 75.5 1.8 6e-21 74.0 1.3 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 GAO84752.1 - 2.2e-06 27.1 0.0 0.0013 18.1 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.5 GAO84753.1 - 1.1e-37 128.7 0.0 1.6e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 GAO84753.1 - 9.6e-08 32.0 0.0 8.7e-06 25.8 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ribosomal_L27 PF01016.14 GAO84754.1 - 8e-26 89.6 0.0 1.4e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.10 GAO84755.1 - 3.1e-40 137.5 0.4 1.3e-21 76.7 0.0 3.1 1 1 0 2 2 2 2 Scramblase UQ_con PF00179.21 GAO84756.1 - 2.2e-51 172.9 0.0 2.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAO84756.1 - 0.11 12.3 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 RWD domain Prenyltrans_2 PF13249.1 GAO84757.1 - 1.9e-34 118.4 1.6 1.8e-16 60.5 0.2 5.3 4 1 2 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 GAO84757.1 - 1.1e-29 101.6 7.6 8.6e-09 34.8 0.1 5.5 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 GAO84757.1 - 1.8e-27 95.5 0.1 6.8e-12 45.3 0.1 5.9 4 2 1 5 5 5 4 Prenyltransferase-like SGS PF05002.10 GAO84757.1 - 2.4e-27 94.5 1.7 5.6e-27 93.3 1.2 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 GAO84757.1 - 9.1e-15 54.9 0.0 2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 CS domain Pec_lyase PF09492.5 GAO84757.1 - 1.3e-07 31.1 3.6 0.44 9.6 0.0 5.4 3 1 2 5 5 5 3 Pectic acid lyase TPR_11 PF13414.1 GAO84757.1 - 9.6e-06 25.1 0.6 4.4e-05 23.0 0.2 2.2 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 GAO84757.1 - 0.24 12.1 2.0 6.3 7.6 0.0 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Herpes_pp38 PF04846.8 GAO84757.1 - 0.26 10.6 0.0 0.59 9.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein TPR_9 PF13371.1 GAO84757.1 - 0.49 10.2 3.2 23 4.9 1.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat PQ-loop PF04193.9 GAO84758.1 - 4.9e-40 134.8 17.3 4.4e-21 74.1 0.9 2.9 3 0 0 3 3 3 2 PQ loop repeat FixQ PF05545.6 GAO84758.1 - 2.2 8.0 4.9 32 4.2 0.0 3.6 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ SIR2 PF02146.12 GAO84759.1 - 3e-32 111.7 0.0 4.7e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Pkinase PF00069.20 GAO84760.1 - 5e-77 258.5 0.0 6e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84760.1 - 8.9e-38 129.8 0.0 1.3e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO84760.1 - 0.00015 20.7 0.5 0.00052 19.0 0.0 2.1 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 GAO84760.1 - 0.0044 16.0 1.5 0.0098 14.9 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO84760.1 - 0.03 14.0 0.7 0.096 12.3 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO84760.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Dicty_CAR PF05462.6 GAO84761.1 - 8.7e-10 37.9 18.7 6.9e-09 35.0 8.3 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAO84761.1 - 1.5e-09 37.3 7.7 2.6e-09 36.5 5.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 GAO84761.1 - 0.0015 18.1 11.2 0.0032 17.0 7.8 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Nnf1 PF03980.9 GAO84762.1 - 1.3e-36 124.8 1.4 2.6e-36 123.9 1.0 1.5 1 0 0 1 1 1 1 Nnf1 Cortex-I_coil PF09304.5 GAO84762.1 - 0.0022 17.9 1.2 0.11 12.5 0.1 2.4 2 0 0 2 2 2 1 Cortexillin I, coiled coil DMPK_coil PF08826.5 GAO84762.1 - 0.0049 16.7 0.3 0.0049 16.7 0.2 2.3 3 0 0 3 3 3 1 DMPK coiled coil domain like DivIC PF04977.10 GAO84762.1 - 0.014 14.8 0.5 0.014 14.8 0.3 1.9 2 0 0 2 2 2 0 Septum formation initiator Apolipoprotein PF01442.13 GAO84762.1 - 0.027 13.9 3.3 0.029 13.8 0.8 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CR6_interact PF10147.4 GAO84762.1 - 0.044 13.1 1.2 0.16 11.2 0.2 2.0 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4140 PF13600.1 GAO84762.1 - 0.1 13.0 2.9 0.23 11.9 0.4 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc42p PF11544.3 GAO84762.1 - 0.18 11.7 1.0 0.8 9.6 0.0 2.5 2 1 1 3 3 3 0 Spindle pole body component Spc42p WXG100 PF06013.7 GAO84762.1 - 0.65 10.0 4.7 0.91 9.5 1.7 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG APG6 PF04111.7 GAO84762.1 - 0.68 8.9 2.9 0.98 8.4 2.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 GAO84762.1 - 1.7 8.4 5.5 0.94 9.3 1.9 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_fiss_reg PF05308.6 GAO84762.1 - 1.8 7.8 7.0 5.6 6.2 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator FliT PF05400.8 GAO84762.1 - 5 7.5 10.2 0.52 10.7 2.6 2.5 2 2 0 2 2 2 0 Flagellar protein FliT TPR_11 PF13414.1 GAO84763.1 - 2e-07 30.5 12.2 0.0081 15.7 0.3 5.1 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.1 GAO84763.1 - 0.011 15.8 2.1 1.9 8.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO84763.1 - 0.019 14.9 15.6 0.13 12.2 0.2 5.1 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO84763.1 - 0.1 13.3 20.7 0.29 11.8 1.2 5.4 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84763.1 - 0.13 12.6 12.5 2.2 8.6 0.4 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO84763.1 - 0.88 9.6 7.2 3.6 7.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO84763.1 - 1.5 9.6 16.8 1.6 9.6 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO84763.1 - 3.9 8.1 5.8 20 5.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NTF2 PF02136.15 GAO84765.1 - 7.1e-27 94.1 0.2 1.2e-26 93.3 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAO84765.1 - 1.4e-08 34.2 0.1 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO84765.1 - 2.6e-05 24.1 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO84765.1 - 8.1e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAO84765.1 - 0.047 13.5 0.0 0.047 13.5 0.0 2.1 3 0 0 3 3 3 0 RNA binding motif HSP90 PF00183.13 GAO84766.1 - 1.1e-256 852.4 35.9 1.3e-256 852.1 24.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 GAO84766.1 - 1.2e-11 44.3 0.1 2.1e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAO84766.1 - 2.3e-11 43.4 0.2 2.3e-11 43.4 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 GAO84766.1 - 0.046 13.5 1.6 0.066 12.9 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF1676 PF07898.8 GAO84766.1 - 0.057 13.7 0.5 0.057 13.7 0.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1676) Peptidase_S10 PF00450.17 GAO84766.1 - 0.091 11.9 0.9 0.82 8.7 0.0 2.3 2 1 0 2 2 2 0 Serine carboxypeptidase Septin PF00735.13 GAO84767.1 - 2.2e-12 46.6 0.0 2.5e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Septin Zeta_toxin PF06414.7 GAO84767.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Miro PF08477.8 GAO84767.1 - 0.0075 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAO84767.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 GAO84767.1 - 0.024 14.6 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAO84767.1 - 0.036 13.5 0.6 0.5 9.9 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 GAO84767.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 GAO84767.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 GAO84767.1 - 0.067 14.0 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAO84767.1 - 0.076 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAO84767.1 - 0.08 12.6 0.1 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 GAO84767.1 - 0.084 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 GAO84767.1 - 0.095 11.6 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.1 GAO84767.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAO84767.1 - 0.1 12.9 0.1 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 GAO84767.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 GAO84767.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAO84767.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 GAO84767.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.24 GAO84767.1 - 0.16 12.1 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HLH PF00010.21 GAO84768.1 - 8.4e-15 54.2 1.4 1.8e-14 53.1 1.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_pol_Rpc82 PF05645.8 GAO84769.1 - 3.4e-26 92.3 0.0 8.4e-24 84.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 GAO84769.1 - 1.6e-14 53.4 0.2 2e-06 27.5 0.0 4.0 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 GAO84769.1 - 4.3e-07 29.4 0.1 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit FAM176 PF14851.1 GAO84769.1 - 0.046 13.3 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 FAM176 family Peptidase_M16 PF00675.15 GAO84770.1 - 7.2e-19 68.0 0.3 1.7e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAO84770.1 - 4.1e-15 55.9 0.0 7.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Mito_carr PF00153.22 GAO84771.1 - 4.3e-26 90.4 6.6 3.7e-11 42.5 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 GAO84772.1 - 8.8e-102 340.4 0.0 1.1e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 GAO84773.1 - 1.8e-06 27.4 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO84773.1 - 4.1e-05 23.3 0.0 8.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 GAO84773.1 - 0.00023 21.3 0.0 0.00089 19.4 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 GAO84773.1 - 0.0018 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF935 PF06074.7 GAO84773.1 - 1.6 7.3 8.9 0.039 12.6 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF935) Cys_Met_Meta_PP PF01053.15 GAO84774.1 - 1.7e-151 503.8 0.0 2e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAO84774.1 - 9.3e-15 54.5 0.8 1.6e-14 53.7 0.3 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAO84774.1 - 1.5e-08 33.9 0.1 4.4e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO84774.1 - 7.7e-08 31.8 0.0 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAO84774.1 - 2e-07 30.1 0.2 3.4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 GAO84774.1 - 0.0028 16.4 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 GAO84774.1 - 0.01 14.1 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ADH_zinc_N PF00107.21 GAO84774.1 - 0.045 13.2 0.3 0.22 11.0 0.1 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase SLA_LP_auto_ag PF05889.8 GAO84774.1 - 0.085 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) AA_permease PF00324.16 GAO84775.1 - 3.8e-134 447.6 46.2 3.8e-134 447.6 32.1 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 GAO84775.1 - 1.7e-31 109.1 52.8 1.7e-31 109.1 36.6 2.2 2 0 0 2 2 2 1 Amino acid permease MARVEL PF01284.18 GAO84775.1 - 6.3e-20 71.4 16.8 6.3e-20 71.4 11.6 5.3 3 1 1 4 4 4 1 Membrane-associating domain AMP-binding PF00501.23 GAO84776.1 - 6.4e-80 268.5 0.0 7.9e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 GAO84777.1 - 4.6e-38 129.8 0.0 6.7e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 GAO84778.1 - 5.8e-09 35.6 1.6 1.3e-08 34.5 1.1 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 GAO84778.1 - 2.4e-07 31.0 9.4 2.4e-07 31.0 6.5 2.4 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.27 GAO84779.1 - 6.5e-15 54.3 1.8 0.0013 18.5 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Mito_carr PF00153.22 GAO84780.1 - 1.7e-51 171.8 2.7 7.9e-16 57.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 GAO84780.1 - 0.0028 17.4 0.2 0.0095 15.7 0.1 1.9 2 0 0 2 2 2 1 UcrQ family AphA_like PF14557.1 GAO84780.1 - 0.029 13.8 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF4401 PF14351.1 GAO84780.1 - 0.034 13.1 0.6 0.19 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) Peptidase_M1 PF01433.15 GAO84781.1 - 4.9e-131 437.4 0.4 8.1e-131 436.6 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAO84781.1 - 1.1e-74 251.6 0.8 1.9e-74 250.8 0.6 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAO84781.1 - 1.6e-22 79.9 2.0 3.2e-22 78.9 1.4 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 GAO84782.1 - 3.6e-32 111.5 0.0 4.7e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 GAO84782.1 - 1.8e-08 34.6 0.0 2.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain PUF PF00806.14 GAO84783.1 - 3.1e-33 111.3 3.0 2.1e-06 26.8 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat Abhydrolase_5 PF12695.2 GAO84784.1 - 1.6e-06 27.8 0.2 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO84784.1 - 1.2e-05 25.3 4.2 4.7e-05 23.3 2.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO84784.1 - 5.8e-05 22.6 0.1 0.00013 21.4 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 GAO84784.1 - 6.5e-05 22.2 0.0 0.00015 21.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAO84784.1 - 0.00087 18.7 0.1 0.17 11.2 0.0 2.8 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 GAO84784.1 - 0.0023 17.5 0.1 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 GAO84784.1 - 0.054 12.2 0.3 0.21 10.3 0.1 2.0 2 1 0 2 2 2 0 Chlorophyllase TPT PF03151.11 GAO84785.1 - 3.1e-37 127.5 6.1 4.7e-37 126.9 4.3 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 GAO84785.1 - 0.00078 19.4 25.3 0.011 15.7 8.2 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 GAO84785.1 - 0.00093 18.1 1.4 0.00094 18.1 0.2 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 GAO84785.1 - 0.0048 15.8 12.7 0.075 11.9 8.8 2.1 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.5 GAO84785.1 - 0.023 14.6 0.5 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 CRT-like DUF2178 PF09946.4 GAO84785.1 - 0.3 10.8 4.2 7.5 6.3 1.7 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) PsbX PF06596.6 GAO84785.1 - 2.5 7.8 7.3 0.55 9.9 0.2 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Multi_Drug_Res PF00893.14 GAO84785.1 - 6.4 7.3 9.3 0.8 10.2 1.5 2.5 2 1 0 2 2 2 0 Small Multidrug Resistance protein Molybdopterin PF00384.17 GAO84786.1 - 3.6e-72 243.4 0.0 4.9e-70 236.4 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 GAO84786.1 - 4.3e-20 71.3 0.2 1.1e-19 69.9 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 GAO84786.1 - 2.8e-19 68.0 0.1 8.6e-19 66.4 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 GAO84786.1 - 1.1e-15 57.5 0.0 3.4e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 GAO84786.1 - 1.6e-08 34.1 0.7 1.6e-08 34.1 0.5 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 GAO84786.1 - 0.029 14.1 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 GAO84786.1 - 0.1 12.2 1.0 3 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 GAO84786.1 - 0.24 11.2 2.0 4.2 7.2 1.4 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster XRCC4 PF06632.7 GAO84787.1 - 1.8e-08 33.6 8.8 4.9e-08 32.2 6.1 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sipho_Gp157 PF05565.6 GAO84787.1 - 0.0019 17.7 0.9 0.0035 16.9 0.6 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 DUF3585 PF12130.3 GAO84787.1 - 0.021 14.6 3.3 0.047 13.5 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) DUF4140 PF13600.1 GAO84787.1 - 0.036 14.4 1.7 0.11 12.9 1.1 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.1 GAO84787.1 - 0.37 11.1 5.2 19 5.6 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin ER_lumen_recept PF00810.13 GAO84789.1 - 1.1e-45 155.7 6.8 1.5e-45 155.2 4.7 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAO84789.1 - 0.23 11.0 1.7 3 7.4 0.2 2.5 2 0 0 2 2 2 0 PQ loop repeat DUF382 PF04037.8 GAO84790.1 - 6.9e-62 206.9 0.8 1.2e-61 206.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 GAO84790.1 - 4.5e-21 73.9 8.5 1.1e-20 72.7 5.9 1.7 1 0 0 1 1 1 1 PSP Ribonuclease_3 PF00636.21 GAO84791.1 - 2.6e-15 56.8 0.0 6.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAO84791.1 - 3.6e-12 46.3 0.0 7.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 GAO84791.1 - 0.0046 17.4 0.0 0.0086 16.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif FAD_binding_3 PF01494.14 GAO84793.1 - 2.5e-17 63.0 0.0 1.4e-14 53.9 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO84793.1 - 0.00042 19.3 0.1 0.26 10.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO84793.1 - 0.0011 18.0 0.1 0.61 8.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAO84793.1 - 0.016 15.2 0.1 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO84793.1 - 0.074 12.9 0.1 0.19 11.5 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO84793.1 - 0.1 11.3 0.2 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 GAO84793.1 - 0.11 12.8 0.9 3.9 7.9 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase WHIM3 PF15614.1 GAO84793.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 zf-UBP PF02148.14 GAO84795.1 - 2.6e-13 49.8 2.6 3.6e-13 49.3 1.8 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein GMC_oxred_N PF00732.14 GAO84796.1 - 6e-36 124.1 0.0 3.8e-33 114.9 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO84796.1 - 4.5e-31 108.0 0.0 9.9e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO84796.1 - 1.6e-07 30.5 0.0 2.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAO84796.1 - 2.3e-05 24.3 0.1 9.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO84796.1 - 8.2e-05 21.6 0.7 0.0094 14.8 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO84796.1 - 0.0013 18.6 0.0 0.0097 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO84796.1 - 0.0047 17.0 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAO84796.1 - 0.0093 15.4 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 GAO84796.1 - 0.015 13.7 0.0 0.028 12.8 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 GAO84796.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 GAO84796.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.4 GAO84796.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain DUF2190 PF09956.4 GAO84796.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) FAD_oxidored PF12831.2 GAO84796.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAO84796.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 GAO84796.1 - 0.22 11.3 0.3 0.6 9.9 0.1 1.8 2 0 0 2 2 2 0 ThiF family Cytochrom_C_2 PF01322.15 GAO84797.1 - 0.051 14.1 0.0 0.051 14.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C' FAD_binding_3 PF01494.14 GAO84800.1 - 1.1e-63 215.4 0.0 1.9e-63 214.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO84800.1 - 3e-05 23.6 0.0 6.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 GAO84800.1 - 7.5e-05 21.7 1.7 0.0064 15.4 0.5 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO84800.1 - 0.0033 16.5 0.0 0.0084 15.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 GAO84800.1 - 0.0036 16.2 0.3 0.007 15.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO84800.1 - 0.0048 15.7 0.4 0.025 13.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO84800.1 - 0.0064 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO84800.1 - 0.016 13.7 0.1 0.025 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 GAO84800.1 - 0.017 15.1 0.1 0.089 12.8 0.0 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAO84800.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAO84800.1 - 0.026 14.4 0.0 0.087 12.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO84800.1 - 0.028 13.5 0.0 0.061 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 GAO84800.1 - 0.17 11.8 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain ketoacyl-synt PF00109.21 GAO84801.1 - 7e-76 255.0 0.1 1.2e-75 254.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO84801.1 - 9.7e-48 163.1 0.0 2.7e-47 161.6 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO84801.1 - 6e-37 126.1 1.1 1.7e-36 124.6 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAO84801.1 - 2.8e-23 82.5 0.0 5e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAO84801.1 - 2.3e-20 72.6 1.3 4.2e-11 42.9 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 GAO84801.1 - 1.2e-18 68.1 0.0 6.6e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAO84801.1 - 9e-11 42.0 0.0 4.3e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84801.1 - 1.8e-07 30.9 0.0 0.00014 21.6 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAO84801.1 - 0.001 18.1 0.2 0.0026 16.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain HEV_ORF1 PF02444.11 GAO84801.1 - 0.022 14.9 1.2 0.068 13.3 0.0 2.4 2 0 0 2 2 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Abhydrolase_1 PF00561.15 GAO84801.1 - 0.045 13.3 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 GAO84801.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AMP-binding PF00501.23 GAO84802.1 - 7.6e-35 120.0 0.0 4.6e-34 117.5 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO84802.1 - 2.6e-27 95.3 0.0 3.8e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAO84802.1 - 1.3e-08 34.9 0.1 9.8e-08 32.1 0.0 2.5 2 1 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAO84802.1 - 0.00031 20.2 0.0 0.00071 19.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO84802.1 - 0.0039 17.1 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase HNH_2 PF13391.1 GAO84802.1 - 0.019 14.7 1.8 0.027 14.2 0.2 2.0 2 0 0 2 2 2 0 HNH endonuclease KR PF08659.5 GAO84802.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 GAO84803.1 - 6.7e-21 74.9 0.7 9.3e-21 74.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO84803.1 - 1.1e-12 48.2 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO84803.1 - 3.4e-06 26.8 0.2 5.9e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAO84803.1 - 0.00041 19.5 0.0 0.0006 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAO84803.1 - 0.00063 19.7 0.2 0.0014 18.6 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAO84803.1 - 0.007 15.8 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO84803.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrwC PF08751.6 GAO84803.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 TrwC relaxase Abhydrolase_6 PF12697.2 GAO84804.1 - 7e-17 62.0 1.6 9.5e-17 61.6 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84804.1 - 5.9e-10 39.0 1.3 1.3e-09 37.9 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO84804.1 - 6.1e-05 22.6 0.1 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAO84804.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase p450 PF00067.17 GAO84805.1 - 1.8e-62 211.3 0.0 2.3e-61 207.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAO84806.1 - 2.1e-40 138.5 55.5 1e-39 136.2 36.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84806.1 - 1.3e-07 30.5 15.9 1.3e-07 30.5 11.0 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter PsbX PF06596.6 GAO84806.1 - 0.56 9.9 0.0 0.56 9.9 0.0 3.3 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Methyltransf_2 PF00891.13 GAO84807.1 - 6.4e-31 107.3 0.0 1.4e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO84807.1 - 0.00042 20.8 0.0 0.0009 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO84807.1 - 0.039 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 GAO84808.1 - 1.5e-28 98.6 6.8 5.9e-13 48.7 0.1 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO84808.1 - 4.6e-26 90.6 11.6 4e-11 42.7 0.7 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Sporozoite_P67 PF05642.6 GAO84808.1 - 0.038 11.8 2.4 0.057 11.2 1.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MADF_DNA_bdg PF10545.4 GAO84808.1 - 0.057 13.6 11.5 0.08 13.1 1.0 3.7 2 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2947 PF11163.3 GAO84808.1 - 0.088 12.3 1.5 0.2 11.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2947) Myb_DNA-bind_5 PF13873.1 GAO84808.1 - 0.15 11.9 8.4 4.6 7.2 1.2 3.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain RecT PF03837.9 GAO84808.1 - 0.18 11.1 1.5 0.73 9.0 0.6 2.2 2 1 0 2 2 2 0 RecT family RXT2_N PF08595.6 GAO84808.1 - 0.56 9.9 2.4 1.5 8.5 0.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Myb_DNA-bind_4 PF13837.1 GAO84808.1 - 0.83 9.8 11.6 1.9 8.7 0.5 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 GAO84808.1 - 1.1 9.1 6.9 34 4.4 4.8 2.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TauD PF02668.11 GAO84809.1 - 5.6e-51 173.6 0.1 7.9e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_28 PF00295.12 GAO84809.1 - 1.8e-29 102.7 1.1 2.7e-29 102.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 GAO84809.1 - 0.0002 21.5 12.8 0.007 16.5 8.8 2.9 1 1 0 1 1 1 1 Pectate lyase superfamily protein MFS_1 PF07690.11 GAO84810.1 - 6.5e-17 61.2 22.2 8.6e-17 60.8 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NmrA PF05368.8 GAO84811.1 - 2.5e-20 72.7 0.0 3.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO84811.1 - 5.9e-12 45.9 0.1 8.4e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO84811.1 - 1.1e-05 24.5 0.6 1.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO84811.1 - 1.5e-05 25.1 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAO84811.1 - 0.00036 20.0 0.4 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAO84811.1 - 0.0013 18.4 0.3 0.0028 17.3 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAO84811.1 - 0.0018 18.1 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAO84811.1 - 0.01 16.2 0.8 0.026 14.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.3 GAO84812.1 - 0.0008 18.1 2.0 0.001 17.7 0.0 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 GAO84813.1 - 2.2e-47 161.4 0.9 2.9e-47 161.1 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Orthoreo_P17 PF07272.6 GAO84813.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 Orthoreovirus P17 protein Methyltransf_23 PF13489.1 GAO84814.1 - 7.4e-14 51.7 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84814.1 - 1.2e-13 50.9 0.0 1.1e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84814.1 - 5.9e-10 39.5 0.0 2.2e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84814.1 - 3.7e-08 33.9 0.0 3.3e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO84814.1 - 4.8e-08 33.3 0.0 1.4e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO84814.1 - 0.00052 20.0 0.0 0.0016 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO84814.1 - 0.05 13.9 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 GAO84815.1 - 6.1e-172 571.7 0.0 3e-90 302.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO84815.1 - 8.5e-53 179.1 2.5 1e-23 83.6 0.0 3.7 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 GAO84815.1 - 1.3e-18 66.9 2.7 2.5e-08 34.0 0.0 2.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO84815.1 - 1.4e-15 57.9 0.4 6.1e-07 30.2 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain O-FucT PF10250.4 GAO84815.1 - 0.018 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Flg_hook PF02120.11 GAO84815.1 - 0.11 12.2 1.2 0.25 11.0 0.2 2.1 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK MFS_1 PF07690.11 GAO84817.1 - 2.2e-39 135.1 57.7 1.5e-38 132.4 40.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO84817.1 - 8.1e-08 31.2 15.6 8.1e-08 31.2 10.8 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter Lambda_CIII PF02061.11 GAO84818.1 - 0.11 12.5 0.1 13 5.8 0.0 2.7 1 1 1 2 2 2 0 Lambda Phage CIII Amidase PF01425.16 GAO84819.1 - 1.5e-86 291.0 0.0 1.7e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.23 GAO84820.1 - 0 1027.2 4.2 2.8e-80 269.7 0.2 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 GAO84820.1 - 5.3e-138 458.9 0.0 2.8e-39 134.7 0.0 6.2 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.20 GAO84820.1 - 1.2e-34 118.3 2.3 5.8e-08 32.8 0.0 5.6 6 0 0 6 6 6 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO84820.1 - 3.5e-26 91.9 0.1 2.2e-06 28.4 0.0 5.1 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAO84820.1 - 0.26 9.7 0.0 8.6 4.7 0.0 3.0 3 0 0 3 3 3 0 GH3 auxin-responsive promoter DUF3381 PF11861.3 GAO84820.1 - 5.8 6.4 0.0 11 5.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YqcI_YcgG PF08892.6 GAO84821.1 - 5.2e-36 124.2 0.0 7.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 YqcI/YcgG family Amidinotransf PF02274.12 GAO84821.1 - 5e-08 32.3 0.0 0.0019 17.3 0.0 2.4 2 1 0 2 2 2 2 Amidinotransferase Cys_Met_Meta_PP PF01053.15 GAO84822.1 - 9.4e-30 103.1 0.0 1.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAO84822.1 - 4.7e-06 25.7 0.0 7.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PhyH PF05721.8 GAO84824.1 - 3.9e-14 53.1 0.5 6.8e-14 52.4 0.4 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Arylsulfotran_2 PF14269.1 GAO84825.1 - 9.4e-49 166.1 0.0 1.2e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO84825.1 - 1.2e-14 53.7 0.7 5.7e-14 51.5 0.3 2.0 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) AP_endonuc_2 PF01261.19 GAO84826.1 - 3.9e-17 62.2 0.0 5.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_transf_28 PF03033.15 GAO84827.1 - 1.9e-19 69.7 0.0 7.7e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAO84827.1 - 5.1e-07 28.6 0.0 7.5e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAO84827.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 GAO84828.1 - 8.5e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO84828.1 - 4.7e-10 39.7 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAO84828.1 - 4.2e-05 23.7 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox_2 PF07992.9 GAO84829.1 - 2.7e-11 43.7 0.6 4.1e-10 39.8 0.4 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO84829.1 - 6.7e-10 39.2 1.3 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO84829.1 - 8.2e-09 35.8 3.6 0.01 15.9 0.0 3.8 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO84829.1 - 0.08 11.7 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ABC2_membrane PF01061.19 GAO84830.1 - 1.1e-81 273.0 62.8 3.5e-42 143.9 17.1 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO84830.1 - 1.4e-36 124.2 2.1 6.8e-31 105.9 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 GAO84830.1 - 1.3e-32 112.9 0.0 3.8e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 GAO84830.1 - 7.5e-18 64.4 0.0 1.7e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO84830.1 - 4e-07 29.6 0.0 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 GAO84830.1 - 3.8e-06 26.1 26.1 3.8e-06 26.1 18.1 2.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 GAO84830.1 - 0.00078 18.9 0.2 0.035 13.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO84830.1 - 0.0009 18.4 0.0 0.0053 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAO84830.1 - 0.0023 17.7 0.1 0.079 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO84830.1 - 0.0025 17.0 0.0 1.1 8.5 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 GAO84830.1 - 0.0035 16.7 0.7 0.0076 15.7 0.5 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAO84830.1 - 0.0043 17.0 0.4 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAO84830.1 - 0.0051 16.3 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAO84830.1 - 0.015 16.0 0.0 0.2 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAO84830.1 - 0.022 14.4 0.1 0.83 9.4 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 GAO84830.1 - 0.03 14.6 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO84830.1 - 0.049 13.7 0.3 0.72 9.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 GAO84830.1 - 0.055 13.4 0.6 0.91 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 GAO84830.1 - 0.062 12.9 0.3 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAO84830.1 - 0.26 10.9 1.8 1.7 8.3 0.1 2.7 3 0 0 3 3 3 0 NACHT domain FAD_binding_4 PF01565.18 GAO84831.1 - 2e-27 95.3 2.0 4.4e-27 94.2 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BNIP3 PF06553.7 GAO84832.1 - 0.00079 18.8 0.2 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 BNIP3 Inhibitor_Mig-6 PF11555.3 GAO84832.1 - 0.13 12.6 0.1 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Glyco_hydro_10 PF00331.15 GAO84833.1 - 9.1e-83 277.9 0.2 1e-82 277.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SAP PF02037.22 GAO84833.1 - 0.085 12.3 0.0 5.9 6.5 0.0 2.8 3 0 0 3 3 3 0 SAP domain Molybdopterin PF00384.17 GAO84834.1 - 2.3e-69 234.2 0.0 3e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 GAO84834.1 - 8.9e-28 96.3 0.0 2.4e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 GAO84834.1 - 5.4e-14 51.7 1.6 7.6e-14 51.2 0.3 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF977 PF06163.6 GAO84834.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) MoCF_biosynth PF00994.19 GAO84835.1 - 1.7e-30 105.3 0.0 2.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 GAO84835.1 - 7.1e-30 103.4 0.3 1.1e-29 102.8 0.2 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAO84835.1 - 5.6e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Abhydrolase_6 PF12697.2 GAO84837.1 - 1.7e-13 51.0 0.5 1.9e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84837.1 - 6e-08 32.5 0.0 9.9e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MTD PF01993.13 GAO84837.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase A_deaminase PF00962.17 GAO84838.1 - 6.3e-42 143.6 0.0 9.4e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Casein_kappa PF00997.13 GAO84838.1 - 1.2 8.8 4.8 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Kappa casein AMP-binding PF00501.23 GAO84839.1 - 5.2e-09 34.9 0.1 8.9e-09 34.2 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme ubiquitin PF00240.18 GAO84839.1 - 0.04 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family HEAT PF02985.17 GAO84839.1 - 0.089 12.9 0.1 14 6.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat p450 PF00067.17 GAO84840.1 - 1.8e-48 165.2 0.0 2.3e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.1 GAO84841.1 - 5.9e-18 62.8 0.4 0.00025 20.8 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 GAO84841.1 - 4.3e-07 29.3 0.5 0.037 13.6 0.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) OTT_1508_deam PF14441.1 GAO84847.1 - 9.8e-10 38.3 0.0 2.4e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.13 GAO84847.1 - 2.1e-09 37.0 5.9 6.2e-09 35.5 4.1 1.8 1 0 0 1 1 1 1 MYND finger PNP_UDP_1 PF01048.15 GAO84849.1 - 7.3e-15 54.5 0.0 2.2e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAO84850.1 - 9.6e-49 163.6 0.1 6.2e-18 64.9 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84850.1 - 2.8e-41 137.3 0.0 4.8e-06 26.1 0.0 7.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 GAO84850.1 - 4e-38 128.5 0.2 2.3e-10 40.3 0.0 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO84850.1 - 5.9e-35 119.0 0.3 8.5e-09 35.6 0.0 5.9 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO84850.1 - 8.6e-33 109.1 0.2 0.00026 20.9 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Sugar_tr PF00083.19 GAO84851.1 - 7.3e-104 347.8 26.4 8.6e-104 347.6 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84851.1 - 1.6e-16 59.9 41.3 7.1e-09 34.8 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_red_sm PF00268.16 GAO84851.1 - 0.067 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain LysM PF01476.15 GAO84852.1 - 3.7e-22 77.9 0.0 5.7e-06 26.1 0.0 4.5 4 0 0 4 4 4 3 LysM domain DUF2960 PF11173.3 GAO84852.1 - 0.049 13.9 0.0 76 3.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2960) TRL PF13146.1 GAO84852.1 - 0.19 11.7 9.1 11 6.0 0.3 3.4 3 0 0 3 3 3 0 TRL-like protein family Rubella_E2 PF05749.6 GAO84852.1 - 0.58 9.3 24.4 0.19 10.9 0.4 3.3 2 1 1 3 3 3 0 Rubella membrane glycoprotein E2 SSP160 PF06933.6 GAO84852.1 - 3.4 5.5 35.5 0.66 7.8 1.3 3.2 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 GAO84852.1 - 6.9 6.4 39.7 0.6 9.8 3.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.23 GAO84854.1 - 2.8e-48 165.1 2.2 6.9e-48 163.8 1.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAO84854.1 - 8.6e-13 47.9 0.2 2.4e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 GAO84854.1 - 0.00057 19.8 7.1 0.00057 19.8 4.9 3.0 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 GAO84854.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Pkinase PF00069.20 GAO84855.1 - 3.7e-37 127.8 0.0 5.6e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAO84855.1 - 1.2e-22 80.0 0.1 9.2e-11 41.9 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 GAO84855.1 - 1.2e-15 57.2 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 GAO84855.1 - 1.4e-14 53.0 4.2 0.00053 19.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAO84855.1 - 2e-13 50.4 1.3 0.0048 17.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO84855.1 - 2e-13 49.1 0.7 0.0036 17.4 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAO84855.1 - 3.1e-08 33.6 2.9 0.075 13.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Kinase-like PF14531.1 GAO84855.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like adh_short PF00106.20 GAO84856.1 - 1.4e-10 41.3 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO84856.1 - 6.5e-06 26.2 0.0 5.3e-05 23.3 0.0 2.3 2 1 0 3 3 3 1 NADH(P)-binding adh_short_C2 PF13561.1 GAO84856.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAO84856.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF4066 PF13278.1 GAO84857.1 - 2.9e-29 101.4 0.0 6.5e-29 100.3 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO84857.1 - 2.8e-15 56.0 0.1 3.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 GAO84857.1 - 0.08 12.3 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Glutamine amidotransferase class-I GFO_IDH_MocA PF01408.17 GAO84860.1 - 7.2e-16 58.7 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox_3 PF13738.1 GAO84861.1 - 1.2e-22 81.0 0.0 2.3e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO84861.1 - 4.9e-20 71.2 0.1 5.3e-17 61.2 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAO84861.1 - 1.3e-10 41.1 0.0 5e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAO84861.1 - 2e-05 23.6 0.1 0.00043 19.3 0.0 2.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAO84861.1 - 6.6e-05 22.7 0.8 0.047 13.4 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 GAO84861.1 - 0.0035 16.3 0.0 0.61 8.9 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAO84861.1 - 0.011 14.9 0.0 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 GAO84861.1 - 0.077 11.8 0.1 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Dicistro_VP4 PF11492.3 GAO84861.1 - 0.11 12.5 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 Bac_luciferase PF00296.15 GAO84862.1 - 5.3e-65 219.5 1.3 7.5e-65 219.0 0.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 GAO84863.1 - 3e-07 30.0 0.2 7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO84863.1 - 4.8e-06 26.3 0.0 8.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3606 PF12244.3 GAO84863.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) UvrC_HhH_N PF08459.6 GAO84863.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal AA_permease_2 PF13520.1 GAO84864.1 - 4.5e-84 282.4 23.7 5e-84 282.2 16.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO84864.1 - 4.8e-17 61.4 20.3 6.1e-17 61.1 14.1 1.1 1 0 0 1 1 1 1 Amino acid permease UNC-93 PF05978.11 GAO84866.1 - 1.1e-09 38.0 4.0 1.1e-09 38.0 2.8 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 GAO84866.1 - 7.4e-07 28.1 37.5 7.4e-07 28.1 26.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amastin PF07344.6 GAO84866.1 - 6.6 6.3 12.0 0.75 9.3 1.3 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein Abhydrolase_6 PF12697.2 GAO84867.1 - 1.5e-19 70.8 0.1 1.8e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84867.1 - 6.7e-14 51.8 0.0 9.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO84867.1 - 1.2e-12 47.4 0.0 8.8e-12 44.7 0.0 2.3 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAO84867.1 - 2.6e-11 43.5 0.0 3.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84867.1 - 0.00099 18.3 0.1 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 GAO84867.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 GAO84867.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAO84867.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 GAO84867.1 - 0.0065 15.7 0.2 2.5 7.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAO84867.1 - 0.013 14.9 0.0 3.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.15 GAO84867.1 - 0.029 13.7 0.1 0.063 12.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase LCAT PF02450.10 GAO84867.1 - 0.088 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Glyco_hydro_75 PF07335.6 GAO84868.1 - 1.8e-47 161.0 0.0 2.7e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.13 GAO84868.1 - 5.6 7.1 9.3 1.1 9.3 3.3 2.0 2 0 0 2 2 2 0 EB module Thioredoxin PF00085.15 GAO84869.1 - 8.8e-27 92.8 0.0 9.9e-27 92.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAO84869.1 - 1.2e-05 25.3 0.1 3.6e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAO84869.1 - 0.00093 19.3 0.1 0.009 16.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAO84869.1 - 0.0037 17.2 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAO84869.1 - 0.0054 16.2 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 GAO84869.1 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.4 1 1 1 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 GAO84869.1 - 0.027 14.1 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 GAO84869.1 - 0.03 13.0 0.0 0.032 12.9 0.0 1.0 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.19 GAO84869.1 - 0.04 13.9 0.1 0.068 13.1 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_9 PF14595.1 GAO84869.1 - 0.05 13.1 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Abhydrolase_3 PF07859.8 GAO84870.1 - 8e-44 149.7 0.0 1.2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAO84870.1 - 2.7e-11 42.9 3.3 2e-10 40.0 2.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAO84870.1 - 5.9e-05 22.8 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO84870.1 - 0.0043 16.3 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Cu-oxidase_3 PF07732.10 GAO84871.1 - 3.1e-12 46.2 0.0 1.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO84871.1 - 1.5e-09 37.4 0.1 0.0017 17.8 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 GAO84871.1 - 0.013 15.3 0.0 3 7.8 0.0 2.4 2 1 0 2 2 2 0 Cupredoxin-like domain COesterase PF00135.23 GAO84872.1 - 1.2e-101 341.0 0.0 2.7e-94 316.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO84872.1 - 1.2e-11 44.6 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO84872.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO84872.1 - 0.086 12.0 0.1 0.19 10.9 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAO84872.1 - 0.12 11.7 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Phage_holin_6 PF10746.4 GAO84873.1 - 0.42 10.3 3.4 0.85 9.3 0.3 2.4 2 0 0 2 2 2 0 Phage holin family 6 Inhibitor_I78 PF11720.3 GAO84874.1 - 2.3e-17 62.4 0.0 2.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 GAO84874.1 - 0.0084 16.2 0.0 0.018 15.1 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family DUF2430 PF10353.4 GAO84874.1 - 0.09 12.9 0.0 0.094 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) Methyltransf_23 PF13489.1 GAO84875.1 - 3.3e-19 69.1 0.1 5.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84875.1 - 4.9e-09 36.7 0.0 1.1e-07 32.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84875.1 - 1e-07 31.6 0.0 3.1e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO84875.1 - 0.00022 21.6 0.0 0.0006 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84875.1 - 0.0013 19.1 0.0 0.029 14.8 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO84875.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAO84875.1 - 0.0046 16.9 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 GAO84875.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 GAO84875.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 GAO84875.1 - 0.025 14.9 0.0 0.084 13.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAO84875.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 GAO84875.1 - 0.045 12.8 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 GAO84875.1 - 0.058 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CBS PF00571.23 GAO84875.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 CBS domain DUF938 PF06080.7 GAO84875.1 - 0.13 11.7 0.0 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Trp_DMAT PF11991.3 GAO84876.1 - 2e-86 290.4 0.0 2.3e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase EGF_2 PF07974.8 GAO84878.1 - 0.013 15.6 6.9 0.022 14.9 4.8 1.4 1 0 0 1 1 1 0 EGF-like domain Nodulin_late PF07127.6 GAO84878.1 - 0.22 11.6 1.2 0.39 10.8 0.8 1.4 1 0 0 1 1 1 0 Late nodulin protein hEGF PF12661.2 GAO84878.1 - 1.5 9.0 4.1 0.92 9.7 0.7 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF Beta_helix PF13229.1 GAO84879.1 - 1.1e-09 38.2 17.1 1.6e-08 34.4 4.2 3.5 1 1 2 3 3 3 3 Right handed beta helix region Chondroitinas_B PF14592.1 GAO84879.1 - 1.1e-06 27.7 0.0 2.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 GAO84879.1 - 0.00096 18.3 4.7 0.002 17.2 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) DIOX_N PF14226.1 GAO84880.1 - 2.6e-30 105.3 0.0 1e-28 100.2 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO84880.1 - 1.7e-13 50.7 0.0 3.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MBOAT_2 PF13813.1 GAO84881.1 - 2.2e-22 78.8 6.0 4.9e-22 77.7 4.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family AalphaY_MDB PF04611.7 GAO84881.1 - 0.14 12.0 0.2 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Amidohydro_1 PF01979.15 GAO84882.1 - 7.3e-18 65.2 0.1 1.4e-16 61.0 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAO84882.1 - 4.9e-07 29.3 0.1 8.1e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO84882.1 - 0.00042 20.4 0.1 0.0012 18.9 0.1 1.8 2 0 0 2 2 2 1 Amidohydrolase PLA2_B PF01735.13 GAO84884.1 - 1.4e-164 547.9 1.0 4.6e-150 500.0 0.0 2.2 1 1 1 2 2 2 2 Lysophospholipase catalytic domain FAD_binding_3 PF01494.14 GAO84884.1 - 1e-26 93.8 0.0 2e-25 89.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 GAO84884.1 - 4.4e-17 61.8 17.6 7.2e-17 61.1 12.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_8 PF13450.1 GAO84884.1 - 4.3e-06 26.6 0.1 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO84884.1 - 7.6e-06 26.1 0.0 3e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO84884.1 - 5.2e-05 22.3 0.1 0.015 14.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO84884.1 - 8.4e-05 21.1 0.0 0.0089 14.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAO84884.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO84884.1 - 0.00068 18.5 0.0 0.0025 16.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 GAO84884.1 - 0.0007 19.9 2.6 1.1 9.7 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO84884.1 - 0.0012 17.8 0.1 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAO84884.1 - 0.0016 17.6 0.0 0.87 8.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 GAO84884.1 - 0.0059 15.2 0.1 0.48 8.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 GAO84884.1 - 0.0083 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO84884.1 - 0.0088 15.0 0.0 0.082 11.8 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO84884.1 - 0.11 12.2 0.3 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding E_raikovi_mat PF06360.6 GAO84885.1 - 6.5 7.0 8.8 12 6.1 5.0 2.2 2 1 0 2 2 2 0 Euplotes raikovi mating pheromone ILVD_EDD PF00920.16 GAO84886.1 - 4.8e-204 678.6 0.0 5.6e-204 678.3 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF3996 PF13161.1 GAO84887.1 - 0.16 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) MT0933_antitox PF14013.1 GAO84888.1 - 7.7 6.7 6.9 2.8e+02 1.7 4.8 2.9 1 1 0 1 1 1 0 MT0933-like antitoxin protein TPR_12 PF13424.1 GAO84889.1 - 5.2e-20 71.1 13.0 2.1e-08 33.9 0.2 5.7 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 GAO84889.1 - 1.5e-10 40.6 20.8 0.21 11.5 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat DUF676 PF05057.9 GAO84889.1 - 5.1e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAO84889.1 - 3.6e-05 23.4 0.0 7.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein TPR_7 PF13176.1 GAO84889.1 - 5.2e-05 22.7 4.4 0.031 14.0 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAO84889.1 - 0.00014 21.8 0.1 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_8 PF13181.1 GAO84889.1 - 0.00069 19.2 2.7 0.75 9.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO84889.1 - 0.0013 18.3 0.5 0.62 9.7 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 GAO84889.1 - 0.0014 19.2 2.6 0.53 11.0 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO84889.1 - 0.0033 17.7 2.9 3 8.2 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 GAO84889.1 - 0.0034 17.1 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_2 PF07719.12 GAO84889.1 - 0.0063 16.3 9.2 0.03 14.2 0.8 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO84889.1 - 0.025 14.7 0.5 0.17 12.0 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Lipase_3 PF01764.20 GAO84889.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) TPR_14 PF13428.1 GAO84889.1 - 0.078 13.6 12.0 0.29 11.8 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO84889.1 - 0.15 12.5 11.8 0.054 13.9 1.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAO84889.1 - 2.8 7.6 7.3 0.59 9.8 0.6 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SLAC1 PF03595.12 GAO84890.1 - 3.8e-90 301.8 50.0 4.3e-90 301.6 34.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2248 PF10005.4 GAO84890.1 - 0.15 10.9 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) Dioxygenase_C PF00775.16 GAO84891.1 - 5.9e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Glyco_hydro_43 PF04616.9 GAO84892.1 - 1.7e-11 43.7 0.1 1.9e-10 40.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 GAO84893.1 - 3.6e-49 167.5 0.0 2.7e-43 148.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Cu_amine_oxid PF01179.15 GAO84894.1 - 2.7e-165 550.0 0.0 3.5e-165 549.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Fungal_trans PF04082.13 GAO84894.1 - 3.4e-14 52.3 0.0 8.2e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxidN3 PF02728.11 GAO84894.1 - 1.6e-07 31.3 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Zn_clus PF00172.13 GAO84894.1 - 1.9e-06 27.6 9.4 4.7e-06 26.4 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxidN2 PF02727.11 GAO84894.1 - 0.0036 17.3 0.1 0.0086 16.1 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SlyX PF04102.7 GAO84894.1 - 0.031 14.6 0.2 0.084 13.2 0.1 1.7 1 0 0 1 1 1 0 SlyX His_Phos_2 PF00328.17 GAO84895.1 - 2.3e-13 50.2 0.0 3.7e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Yae1_N PF09811.4 GAO84895.1 - 0.047 13.2 1.6 0.081 12.4 1.1 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal MFS_1 PF07690.11 GAO84897.1 - 9.8e-39 133.0 48.8 2.3e-38 131.8 33.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 GAO84897.1 - 0.00018 20.3 16.7 0.0025 16.6 1.8 2.6 2 1 0 2 2 2 2 PUCC protein DUF4212 PF13937.1 GAO84897.1 - 0.063 13.2 0.7 0.46 10.5 0.5 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF2937 PF11157.3 GAO84897.1 - 2.1 7.6 6.6 1.3 8.2 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) Tbf5 PF06331.7 GAO84898.1 - 1.9e-22 78.7 1.1 2.1e-22 78.6 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 GAO84898.1 - 0.15 11.6 0.2 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain HSP20 PF00011.16 GAO84899.1 - 2.7e-19 68.9 0.6 2.1e-13 49.9 0.2 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Abhydrolase_3 PF07859.8 GAO84900.1 - 2.1e-34 118.9 0.0 3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO84900.1 - 0.002 18.0 0.1 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAO84900.1 - 0.0061 15.4 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 GAO84900.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 GAO84900.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 GAO84900.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.23 GAO84900.1 - 0.057 12.1 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.13 GAO84900.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.3 GAO84900.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.6 GAO84900.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase ECH PF00378.15 GAO84901.1 - 1.3e-39 135.8 0.8 2.9e-39 134.6 0.6 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAO84901.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Lipase_GDSL PF00657.17 GAO84902.1 - 5.7e-17 62.3 0.2 7.2e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAO84902.1 - 9e-13 48.7 0.8 1.4e-12 48.1 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Isochorismatase PF00857.15 GAO84903.1 - 1.2e-25 90.4 0.0 4.5e-25 88.5 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 GAO84903.1 - 9.5e-23 81.0 0.0 1.9e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.1 GAO84903.1 - 2.1e-06 27.5 0.1 5.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO84903.1 - 2.4e-06 27.9 0.0 7.1e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO84903.1 - 0.00019 21.3 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy PF03171.15 GAO84903.1 - 0.00023 21.3 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IlvN PF07991.7 GAO84904.1 - 4.5e-46 156.2 0.0 6.5e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 GAO84904.1 - 3.3e-45 153.5 0.0 6.8e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 GAO84904.1 - 0.026 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAO84904.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 GAO84905.1 - 3.3e-75 253.1 0.3 4.3e-75 252.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAO84905.1 - 0.048 12.6 0.1 0.09 11.7 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rad51 PF08423.6 GAO84906.1 - 0.027 13.3 0.0 0.091 11.6 0.0 1.8 2 0 0 2 2 2 0 Rad51 Mitochondr_Som1 PF11093.3 GAO84907.1 - 3.7e-11 42.6 0.0 5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 GAO84908.1 - 6.4e-23 80.5 1.3 6.4e-23 80.5 0.9 2.4 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 GAO84908.1 - 5.9e-09 35.5 0.0 4.8e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated Chitin_synth_1 PF01644.12 GAO84909.1 - 6.2e-69 230.9 0.0 1.5e-68 229.7 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase UQ_con PF00179.21 GAO84909.1 - 7.1e-36 122.7 0.0 1.3e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.6 GAO84909.1 - 1.1e-27 95.5 0.0 2e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAO84909.1 - 4.2e-26 91.4 0.0 3.3e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAO84909.1 - 3.2e-12 46.5 0.0 3.2e-12 46.5 0.0 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO84909.1 - 6.7e-10 39.1 0.0 2.1e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Mid2 PF04478.7 GAO84910.1 - 0.04 13.3 0.0 0.04 13.3 0.0 2.2 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 GAO84910.1 - 0.063 12.9 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4328 PF14219.1 GAO84910.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) P12 PF12669.2 GAO84910.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family EphA2_TM PF14575.1 GAO84910.1 - 0.13 12.6 0.1 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UEV PF05743.8 GAO84913.1 - 1e-33 115.5 0.2 1e-30 105.9 0.1 2.3 2 0 0 2 2 2 2 UEV domain Vps23_core PF09454.5 GAO84913.1 - 1.9e-23 81.8 0.0 4.4e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain IncA PF04156.9 GAO84913.1 - 0.00048 19.7 0.1 0.00087 18.9 0.1 1.4 1 0 0 1 1 1 1 IncA protein CCDC155 PF14662.1 GAO84913.1 - 0.0012 18.4 1.7 0.002 17.7 1.0 1.4 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 UQ_con PF00179.21 GAO84913.1 - 0.0047 16.3 1.3 0.011 15.2 0.4 2.0 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme Striatin PF08232.7 GAO84913.1 - 0.019 15.3 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Striatin family Spectrin PF00435.16 GAO84913.1 - 0.028 14.6 1.0 0.051 13.8 0.7 1.5 1 0 0 1 1 1 0 Spectrin repeat Sipho_Gp157 PF05565.6 GAO84913.1 - 0.057 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 TMF_TATA_bd PF12325.3 GAO84913.1 - 0.12 12.1 0.8 0.19 11.4 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1408 PF07193.6 GAO84913.1 - 0.19 11.2 0.0 1 8.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1408) Reo_sigmaC PF04582.7 GAO84913.1 - 7.9 5.5 11.4 12 4.9 7.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RNA_pol_Rpb1_5 PF04998.12 GAO84914.1 - 2.4e-88 296.0 0.5 4.9e-88 294.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 GAO84914.1 - 7e-85 285.2 0.0 1.1e-84 284.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 GAO84914.1 - 9.9e-67 224.0 0.0 2.5e-66 222.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAO84914.1 - 3.9e-34 117.6 0.0 2.2e-33 115.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAO84914.1 - 1.3e-27 95.6 0.1 4.6e-27 93.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 GAO84914.1 - 9.8 6.1 7.8 0.48 10.3 0.7 2.5 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.22 GAO84915.1 - 3.3e-49 166.8 0.0 5e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 GAO84915.1 - 7.8e-39 131.9 4.3 1.2e-38 131.2 3.0 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 GAO84915.1 - 3.1e-18 65.4 0.0 5.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO84915.1 - 3.6e-05 23.7 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 GAO84915.1 - 4.3e-05 22.9 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 GAO84915.1 - 6.7e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 GAO84915.1 - 0.003 17.3 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 GAO84915.1 - 0.0047 16.1 0.0 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF1836 PF08876.6 GAO84915.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Snurportin1 PF11538.3 GAO84915.1 - 0.65 9.8 3.1 1.1 9.1 0.9 2.1 2 0 0 2 2 2 0 Snurportin1 HORMA PF02301.13 GAO84916.1 - 1.4e-50 171.6 0.3 1.6e-50 171.4 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF218 PF02698.12 GAO84917.1 - 2.4e-07 30.3 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain zf-CCCH PF00642.19 GAO84918.1 - 0.0015 18.1 0.8 0.0023 17.5 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med26 PF08711.6 GAO84918.1 - 0.059 12.8 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Sec1 PF00995.18 GAO84919.1 - 7.2e-158 526.7 0.0 8.4e-158 526.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family STE2 PF02116.10 GAO84920.1 - 3.8e-99 331.3 19.6 4.4e-99 331.0 13.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Kdo PF06293.9 GAO84921.1 - 4.8e-11 42.1 0.0 2.2e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO84921.1 - 3.5e-08 33.4 0.2 0.0021 17.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 GAO84921.1 - 1.1e-07 31.2 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84921.1 - 0.0069 15.4 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAO84921.1 - 0.0073 15.6 0.2 1.1 8.5 0.0 2.5 3 0 0 3 3 3 2 RIO1 family Choline_kinase PF01633.15 GAO84921.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 GAO84922.1 - 3.2e-12 45.8 0.0 4.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 GAO84923.1 - 1.4e-42 145.4 0.0 2.2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family CsbD PF05532.7 GAO84923.1 - 2.5e-22 78.2 13.3 1e-13 50.6 2.9 3.5 2 1 1 3 3 3 2 CsbD-like IDO PF01231.13 GAO84924.1 - 2.3e-175 583.0 0.0 2.7e-175 582.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 GAO84924.1 - 0.086 11.3 0.0 0.51 8.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 GAO84925.1 - 3.7e-97 325.3 0.0 4.5e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO84925.1 - 2.7e-07 30.0 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAO84925.1 - 1.1e-05 24.6 0.0 2.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 GAO84925.1 - 0.0029 16.1 0.0 0.0044 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 GAO84926.1 - 1.9e-62 210.7 8.0 2.4e-62 210.4 5.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAO84926.1 - 6.4e-16 57.4 0.1 1.2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO84926.1 - 1.1e-14 53.7 0.1 2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO84926.1 - 3.3e-11 42.4 0.2 8.6e-11 41.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 GAO84926.1 - 0.0068 15.6 6.9 0.7 9.1 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like AHS1 PF02682.11 GAO84926.1 - 0.035 13.5 0.6 0.081 12.3 0.2 1.7 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 TarH PF02203.10 GAO84926.1 - 0.44 10.3 3.1 0.44 10.3 0.2 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue APG6 PF04111.7 GAO84926.1 - 2 7.3 9.8 7.1 5.5 3.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 GAO84926.1 - 2.5 7.0 7.3 0.44 9.5 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.13 GAO84926.1 - 3.1 6.7 9.7 6.2 5.7 0.0 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF2236 PF09995.4 GAO84930.1 - 5.6e-54 182.9 0.5 6.4e-54 182.7 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.6 GAO84930.1 - 0.034 14.7 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain DUF3712 PF12505.3 GAO84931.1 - 6e-35 119.9 0.8 6e-35 119.9 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Sugar_tr PF00083.19 GAO84932.1 - 6.5e-100 334.8 16.0 8e-100 334.5 11.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84932.1 - 1.3e-21 76.6 27.0 1.7e-19 69.7 10.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C14 PF00656.17 GAO84935.1 - 2.8e-69 233.5 0.0 3.4e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DUF605 PF04652.11 GAO84937.1 - 3.2 7.0 10.5 3.6 6.8 7.2 1.0 1 0 0 1 1 1 0 Vta1 like KTI12 PF08433.5 GAO84938.1 - 1.3e-60 204.9 0.0 2.3e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Methyltransf_16 PF10294.4 GAO84938.1 - 5.9e-16 58.4 0.0 9.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase AAA_33 PF13671.1 GAO84938.1 - 8.7e-06 25.6 0.3 2.2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Methyltransf_23 PF13489.1 GAO84938.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CbiZ PF01955.13 GAO84938.1 - 0.18 11.5 3.6 0.35 10.6 2.5 1.4 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase zf-C2H2 PF00096.21 GAO84939.1 - 0.05 13.9 1.7 1.9 8.9 0.0 3.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO84939.1 - 0.85 10.0 15.9 0.57 10.6 0.2 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger Palm_thioest PF02089.10 GAO84940.1 - 8.4e-60 202.0 0.0 1e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 GAO84940.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 GAO84940.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Med31 PF05669.7 GAO84942.1 - 3.4e-32 110.2 0.0 4.1e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 SOH1 Alk_phosphatase PF00245.15 GAO84943.1 - 7.2e-64 216.0 0.2 1.4e-63 215.0 0.1 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 GAO84943.1 - 1.1e-07 31.3 1.6 4.8e-07 29.2 1.1 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAO84943.1 - 2.1e-06 27.3 0.1 4.5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAO84943.1 - 0.0003 19.3 0.2 0.00045 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 GAO84943.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Metalloenzyme PF01676.13 GAO84943.1 - 0.043 13.1 0.3 0.091 12.1 0.2 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.7 GAO84943.1 - 0.047 12.5 0.2 0.077 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_C16 PF01831.12 GAO84943.1 - 0.13 11.8 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase C16 family Pal1 PF08316.6 GAO84944.1 - 1e-50 171.8 2.6 8.8e-50 168.8 1.8 2.5 1 1 0 1 1 1 1 Pal1 cell morphology protein MCM PF00493.18 GAO84945.1 - 1.5e-138 461.1 0.0 2.2e-138 460.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 GAO84945.1 - 2.8e-36 124.8 43.5 2.8e-36 124.8 30.1 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 GAO84945.1 - 5.7e-18 65.5 0.8 1.1e-17 64.6 0.1 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO84945.1 - 3e-09 36.3 0.1 1.1e-06 28.0 0.1 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO84945.1 - 3.2e-06 26.9 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAO84945.1 - 0.00038 20.0 0.1 0.005 16.4 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAO84945.1 - 0.0009 18.7 0.2 0.006 16.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 GAO84945.1 - 0.074 13.4 0.8 0.29 11.5 0.5 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.1 GAO84945.1 - 0.25 10.5 1.1 0.53 9.5 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 GAO84946.1 - 6.4e-17 61.0 4.5 6.4e-17 61.0 3.1 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) FRG2 PF15315.1 GAO84946.1 - 0.4 10.6 9.4 0.12 12.3 3.1 2.1 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Pkinase PF00069.20 GAO84947.1 - 3.1e-62 210.0 0.0 3.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO84947.1 - 1.2e-30 106.4 0.0 1.8e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO84947.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAO84947.1 - 0.061 13.0 0.0 0.65 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 GAO84948.1 - 4.8e-85 285.8 10.7 6.2e-85 285.4 7.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO84948.1 - 1.1e-34 119.7 51.7 1.1e-31 109.8 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO84948.1 - 0.0018 16.5 1.4 0.0018 16.5 1.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.10 GAO84949.1 - 3.2e-53 180.0 0.0 5e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MIS13 PF08202.6 GAO84949.1 - 7.6e-45 153.2 1.1 9e-44 149.7 0.8 2.5 1 1 0 1 1 1 1 Mis12-Mtw1 protein family C2 PF00168.25 GAO84949.1 - 5.8e-35 119.0 1.0 5.3e-17 61.4 0.0 3.5 3 0 0 3 3 3 2 C2 domain EF-hand_7 PF13499.1 GAO84949.1 - 0.0017 18.4 0.1 0.006 16.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair GAGA PF09237.6 GAO84949.1 - 0.0064 16.0 3.3 0.91 9.1 0.4 3.0 2 0 0 2 2 2 2 GAGA factor EF-hand_1 PF00036.27 GAO84949.1 - 0.02 14.1 0.1 0.053 12.8 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 GAO84949.1 - 0.035 13.9 0.1 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 GAO84949.1 - 0.14 11.5 0.0 0.47 9.8 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF1212 PF06738.7 GAO84950.1 - 1.1e-55 188.0 11.9 4.4e-52 176.3 0.2 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAO84950.1 - 1.7e-32 112.1 11.3 1.7e-32 112.1 7.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Transmemb_17 PF09799.4 GAO84950.1 - 2.4 8.5 6.6 0.37 11.1 0.2 2.6 3 0 0 3 3 3 0 Predicted membrane protein Ank_2 PF12796.2 GAO84952.1 - 3.5e-13 49.6 0.4 5.2e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO84952.1 - 6.7e-13 47.7 1.0 1.1e-09 37.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAO84952.1 - 3.8e-12 46.3 2.1 8.9e-05 22.8 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO84952.1 - 1.8e-11 43.8 0.5 1e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO84952.1 - 2.8e-10 39.3 0.7 6.7e-06 25.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 GAO84952.1 - 0.00019 21.0 0.3 0.00096 18.7 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain NDUF_B7 PF05676.8 GAO84953.1 - 2.9e-33 113.0 3.7 3.5e-33 112.8 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 GAO84953.1 - 0.0014 18.3 1.4 0.0019 17.9 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 GAO84954.1 - 3.4e-155 516.6 0.0 8e-155 515.4 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF4440 PF14534.1 GAO84955.1 - 0.0023 18.0 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) COesterase PF00135.23 GAO84956.1 - 7.6e-111 371.4 0.0 9.2e-111 371.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO84956.1 - 4e-08 33.0 0.2 5.8e-07 29.3 0.2 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO84956.1 - 0.0016 17.6 0.2 0.0029 16.8 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO84956.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GATA PF00320.22 GAO84958.1 - 8.7e-15 53.7 5.2 1.5e-14 53.0 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 GAO84958.1 - 0.21 11.6 1.9 0.47 10.4 1.3 1.6 1 0 0 1 1 1 0 zinc-finger Macro PF01661.16 GAO84959.1 - 4.7e-38 129.7 0.0 7.1e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.18 GAO84960.1 - 6.5e-07 28.9 0.0 1.5e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAO84960.1 - 0.00025 20.5 0.0 0.1 12.1 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF605 PF04652.11 GAO84960.1 - 2.6 7.3 9.1 3.1 7.1 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 GAO84960.1 - 4.1 6.8 6.3 5.9 6.3 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GLTP PF08718.6 GAO84961.1 - 3.4e-45 153.7 0.0 4.5e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Hydrolase PF00702.21 GAO84962.1 - 3.2e-21 76.7 0.0 1.2e-20 74.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAO84962.1 - 1.4e-20 73.3 0.0 1.4e-20 73.3 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 GAO84962.1 - 1.7e-20 74.0 0.0 3.4e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO84962.1 - 0.00031 20.6 0.0 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO84962.1 - 0.0019 17.7 0.1 0.0054 16.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAO84962.1 - 0.021 14.1 0.4 0.17 11.1 0.0 2.5 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.16 GAO84964.1 - 2.1e-22 78.7 20.7 2.5e-16 59.2 2.3 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 GAO84964.1 - 0.014 15.5 14.3 0.067 13.3 0.0 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 GAO84964.1 - 0.018 14.8 7.5 0.018 14.8 5.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger U3_assoc_6 PF08640.6 GAO84964.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Rbsn PF11464.3 GAO84964.1 - 0.083 12.4 0.2 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-TFIIB PF13453.1 GAO84964.1 - 0.41 9.8 5.8 26 4.1 2.2 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger Rep_fac-A_C PF08646.5 GAO84964.1 - 1 9.0 10.3 0.54 9.9 2.6 2.7 2 1 0 2 2 2 0 Replication factor-A C terminal domain TMF_TATA_bd PF12325.3 GAO84964.1 - 1 9.0 6.6 0.28 10.9 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding IBR PF01485.16 GAO84964.1 - 9.9 6.1 21.1 0.031 14.1 1.9 3.2 4 0 0 4 4 4 0 IBR domain Abhydrolase_6 PF12697.2 GAO84966.1 - 1.4e-11 44.7 6.8 1.8e-11 44.3 4.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84966.1 - 4.5e-06 26.4 0.1 7.9e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 GAO84967.1 - 1.3e-33 116.4 0.0 6.4e-25 87.9 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO84967.1 - 9.3e-27 94.0 0.0 1.8e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAO84967.1 - 0.00039 20.3 0.2 0.0016 18.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO84967.1 - 0.018 13.9 0.1 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO84967.1 - 0.022 13.6 0.1 0.62 8.8 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 GAO84967.1 - 0.037 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO84967.1 - 0.08 12.7 0.1 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding GDI PF00996.13 GAO84967.1 - 0.11 10.7 0.1 0.17 10.1 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF3328 PF11807.3 GAO84968.1 - 6.1e-37 127.4 1.8 6.3e-36 124.0 1.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Cauli_VI PF01693.11 GAO84968.1 - 0.046 13.7 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Caulimovirus viroplasmin PRCH PF03967.8 GAO84969.1 - 0.00024 20.6 1.0 0.057 12.9 0.0 2.1 1 1 1 2 2 2 2 Photosynthetic reaction centre, H-chain N-terminal region DUF1502 PF07397.6 GAO84969.1 - 0.0066 16.0 0.7 3.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Repeat of unknown function (DUF1502) PS_Dcarbxylase PF02666.10 GAO84970.1 - 2.1e-51 174.0 0.0 2.6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TPK_B1_binding PF04265.9 GAO84970.1 - 0.11 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Acetyltransf_1 PF00583.19 GAO84971.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO84971.1 - 0.00012 22.1 0.0 0.00032 20.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO84971.1 - 0.0059 16.7 0.1 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO84971.1 - 0.043 13.6 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DNA_ligase_A_N PF04675.9 GAO84971.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 DNA ligase N terminus HSP70 PF00012.15 GAO84974.1 - 0.00024 19.1 0.0 0.00066 17.7 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO84974.1 - 0.052 12.1 0.1 0.75 8.3 0.0 2.5 3 0 0 3 3 3 0 MreB/Mbl protein Ctr PF04145.10 GAO84975.1 - 3.5e-34 117.9 0.0 4.9e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Cytochrom_B561 PF03188.11 GAO84976.1 - 2.2e-06 27.5 11.4 7.3e-06 25.8 7.9 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAO84976.1 - 0.18 11.4 6.5 0.4 10.2 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Lamp PF01299.12 GAO84977.1 - 0.26 10.4 12.8 0.27 10.3 4.1 2.1 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Mucin PF01456.12 GAO84977.1 - 1 9.1 34.4 3 7.6 15.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF822 PF05687.8 GAO84977.1 - 1.9 8.8 8.8 0.61 10.4 2.5 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) SSP160 PF06933.6 GAO84977.1 - 4.6 5.0 39.4 1.4 6.8 2.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 GAO84977.1 - 5.1 7.1 13.6 0.31 11.0 3.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region KAR9 PF08580.5 GAO84977.1 - 6.7 4.8 8.5 0.76 7.9 2.0 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 YopH_N PF09013.5 GAO84979.1 - 0.18 11.4 0.2 0.74 9.4 0.1 2.0 2 0 0 2 2 2 0 YopH, N-terminal PhoD PF09423.5 GAO84980.1 - 1.5e-09 36.9 0.0 4.5e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase zf-C2H2_4 PF13894.1 GAO84981.1 - 0.0017 18.5 27.9 0.19 12.1 4.5 4.8 3 1 0 3 3 3 3 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.11 GAO84981.1 - 0.074 12.8 0.5 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain APH PF01636.18 GAO84982.1 - 1.2e-18 67.7 0.1 1.6e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO84982.1 - 0.0037 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAO84982.1 - 0.088 12.1 0.1 0.72 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Ferritin_2 PF13668.1 GAO84984.1 - 6.8e-14 51.9 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PNP_UDP_1 PF01048.15 GAO84985.1 - 2.3e-06 26.7 0.0 4.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Alginate_lyase PF05426.7 GAO84986.1 - 1.2e-16 60.9 0.9 2.5e-16 59.8 0.7 1.4 1 1 0 1 1 1 1 Alginate lyase ABC2_membrane PF01061.19 GAO84987.1 - 3.3e-87 291.0 61.9 2.9e-47 160.5 16.8 2.8 4 0 0 4 4 2 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO84987.1 - 8.1e-33 112.1 8.4 1.8e-30 104.6 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 GAO84987.1 - 7e-32 110.5 0.0 3.3e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 GAO84987.1 - 1.8e-20 72.7 0.0 3.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 GAO84987.1 - 5.9e-08 32.9 0.1 1.8e-05 24.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAO84987.1 - 1.3e-07 31.2 0.0 0.00037 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAO84987.1 - 7.8e-07 28.4 37.1 0.00025 20.1 4.4 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 GAO84987.1 - 1.3e-05 24.6 0.2 0.025 14.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAO84987.1 - 0.00025 20.2 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAO84987.1 - 0.00032 20.5 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO84987.1 - 0.00094 18.4 0.0 5.3 6.2 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAO84987.1 - 0.001 19.8 0.0 2.1 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 GAO84987.1 - 0.0016 17.8 0.1 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 GAO84987.1 - 0.0029 17.6 0.0 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAO84987.1 - 0.0037 17.3 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAO84987.1 - 0.012 15.6 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAO84987.1 - 0.019 15.2 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO84987.1 - 0.024 14.9 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAO84987.1 - 0.048 13.3 0.3 4.4 6.9 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 GAO84987.1 - 0.05 13.3 4.4 4.6 7.0 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain AAA_10 PF12846.2 GAO84987.1 - 0.068 12.6 0.4 15 4.9 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 GAO84987.1 - 0.092 12.7 0.0 24 4.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 GAO84987.1 - 0.21 11.2 0.1 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zn_clus PF00172.13 GAO84988.1 - 6.4e-10 38.7 10.6 1.3e-09 37.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO84988.1 - 8.7e-09 34.6 0.3 1.4e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adeno_E1A PF02703.9 GAO84988.1 - 0.21 10.9 3.4 0.45 9.9 2.3 1.4 1 0 0 1 1 1 0 Early E1A protein Isochorismatase PF00857.15 GAO84989.1 - 6.5e-37 127.1 0.0 1.4e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Iso_dh PF00180.15 GAO84989.1 - 3.8e-14 52.3 0.0 5.9e-13 48.4 0.0 2.2 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.1 GAO84990.1 - 7.1e-15 55.0 0.1 1.9e-07 30.9 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAO84990.1 - 8.2e-11 42.1 0.0 1.5e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO84990.1 - 3.7e-09 37.1 0.0 0.0012 19.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 GAO84990.1 - 1.7e-08 34.2 0.0 0.0015 18.1 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAO84990.1 - 6.5e-08 32.9 0.0 0.011 16.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 GAO84990.1 - 6.2e-07 29.8 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 GAO84990.1 - 0.00025 21.0 0.0 0.88 9.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.7 GAO84990.1 - 0.035 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 GAO84990.1 - 0.042 14.6 0.0 0.39 11.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 GAO84991.1 - 8.6e-41 139.8 68.0 1.9e-35 122.2 24.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO84991.1 - 9.5e-25 86.8 22.6 1.3e-24 86.3 15.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO84991.1 - 4.4e-13 48.6 16.8 4.4e-13 48.6 11.6 3.6 3 2 0 3 3 3 2 Sugar (and other) transporter HsbA PF12296.3 GAO84992.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A F-box-like PF12937.2 GAO84993.1 - 0.00011 21.7 0.7 0.00011 21.7 0.5 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAO84993.1 - 0.00076 19.0 0.8 0.00076 19.0 0.5 2.5 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.1 GAO84993.1 - 0.38 10.9 3.7 12 6.2 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Abhydrolase_6 PF12697.2 GAO84994.1 - 4.2e-07 30.0 3.2 8.7e-07 29.0 2.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO84994.1 - 1.7e-05 24.5 0.5 0.00014 21.6 0.1 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO84994.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 GAO84994.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PKD_channel PF08016.7 GAO84995.1 - 0.0011 17.4 21.3 0.0084 14.5 14.9 2.2 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.7 GAO84996.1 - 5.7e-41 138.8 0.0 1.2e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 GAO84996.1 - 1.2e-10 41.3 0.3 2.6e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 GAO84997.1 - 1.8e-54 184.6 4.9 2e-54 184.4 1.9 1.9 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAO84997.1 - 2.3e-26 91.2 2.6 2.3e-26 91.2 1.8 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAO84997.1 - 1.6e-17 62.9 0.0 3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 GAO84997.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 STAS domain CENP-L PF13092.1 GAO84998.1 - 1.3e-53 181.0 0.0 2.3e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 F-box-like PF12937.2 GAO84998.1 - 6e-05 22.6 0.5 0.00018 21.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO84998.1 - 8.3e-05 22.1 0.0 0.00024 20.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 GAO84998.1 - 0.16 11.9 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 PRANC domain adh_short PF00106.20 GAO84999.1 - 9.3e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO84999.1 - 0.00075 19.2 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO84999.1 - 0.034 13.9 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Band_7 PF01145.20 GAO85000.1 - 4.8e-26 91.7 2.0 9.3e-26 90.8 1.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family COG5 PF10392.4 GAO85001.1 - 0.0036 17.2 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.4 GAO85001.1 - 0.0044 15.0 0.0 0.081 10.8 0.0 2.1 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Ku_PK_bind PF08785.6 GAO85001.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Ku C terminal domain like Baculo_PEP_C PF04513.7 GAO85001.1 - 0.04 13.7 2.8 0.19 11.5 0.5 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 GAO85001.1 - 0.12 12.2 4.8 0.34 10.6 1.2 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RNA_pol_Rpb4 PF03874.11 GAO85003.1 - 4.5e-08 33.1 0.0 0.006 16.5 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.13 GAO85004.1 - 1.5e-55 186.6 1.1 3e-55 185.6 0.8 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAO85004.1 - 1.4e-27 95.2 0.1 2.5e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAO85004.1 - 4.3e-24 84.4 2.0 2.5e-23 81.9 1.4 2.5 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HWE_HK PF07536.9 GAO85004.1 - 0.051 14.0 0.8 20 5.6 0.0 3.1 3 0 0 3 3 3 0 HWE histidine kinase vATP-synt_AC39 PF01992.11 GAO85005.1 - 1.7e-107 359.4 0.0 1.9e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 GAO85006.1 - 5.4e-39 133.8 2.7 3.5e-34 118.1 0.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 GAO85006.1 - 4.9e-32 110.0 0.0 1.6e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 GAO85006.1 - 3.4e-11 42.9 0.2 9.6e-11 41.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAO85006.1 - 0.001 18.3 0.2 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.18 GAO85007.1 - 0.00036 19.8 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 GAO85007.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD SAGA-Tad1 PF12767.2 GAO85007.1 - 0.29 10.7 3.3 0.32 10.6 2.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ERK-JNK_inhib PF15002.1 GAO85007.1 - 2.1 7.6 6.8 3 7.1 4.7 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor PseudoU_synth_1 PF01416.15 GAO85008.1 - 1.4e-27 96.1 0.0 9.2e-22 77.4 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 GAO85009.1 - 2.4e-16 59.5 0.0 3.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO85009.1 - 0.0093 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ribosomal_S2 PF00318.15 GAO85010.1 - 1.1e-43 148.8 0.0 2.7e-23 82.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 GAO85011.1 - 1.5e-20 72.7 1.2 2.9e-20 71.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 DUF892 PF05974.7 GAO85011.1 - 0.0066 16.2 0.2 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DEAD PF00270.24 GAO85014.1 - 3.7e-36 124.1 0.0 1.1e-35 122.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 GAO85014.1 - 4e-20 71.1 0.0 1.1e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAO85014.1 - 9e-19 67.1 0.0 2.4e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO85014.1 - 0.0041 16.9 1.0 0.024 14.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAO85014.1 - 0.036 14.2 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RC-P840_PscD PF10657.4 GAO85014.1 - 0.18 11.6 1.2 0.35 10.6 0.8 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD UvrD-helicase PF00580.16 GAO85014.1 - 0.22 10.7 9.9 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1289 PF06945.8 GAO85014.1 - 4.2 6.9 7.3 1.2 8.7 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) CTP_transf_1 PF01148.15 GAO85015.1 - 5.6e-16 58.9 4.8 6.4e-14 52.2 1.7 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family S100PBPR PF15427.1 GAO85015.1 - 0.11 11.6 1.1 0.13 11.2 0.8 1.1 1 0 0 1 1 1 0 S100P-binding protein XPG_I PF00867.13 GAO85016.1 - 3.4e-22 78.2 0.0 8.4e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAO85016.1 - 5.3e-07 29.8 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 GAO85017.1 - 3e-28 98.3 0.0 9.7e-23 80.2 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 GAO85017.1 - 0.0075 14.9 0.0 0.025 13.1 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Aldose_epim PF01263.15 GAO85018.1 - 8.2e-46 156.4 0.1 1.2e-45 155.9 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase AT_hook PF02178.14 GAO85019.1 - 0.026 14.1 18.6 0.25 11.1 2.8 3.5 2 0 0 2 2 2 0 AT hook motif CDK5_activator PF03261.10 GAO85019.1 - 0.062 12.6 0.6 0.23 10.7 0.4 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NESP55 PF06390.7 GAO85020.1 - 0.01 15.2 2.9 0.015 14.7 2.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.20 GAO85021.1 - 4.7e-12 45.6 0.0 4.5e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85021.1 - 3.6e-08 32.8 0.0 3.6e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85021.1 - 0.017 14.1 0.0 0.037 12.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_72 PF03198.9 GAO85022.1 - 1.2e-101 339.8 0.0 1.7e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 GAO85022.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Sds3 PF08598.6 GAO85025.1 - 1.6e-53 181.3 1.8 9.7e-52 175.4 1.3 2.2 1 1 0 1 1 1 1 Sds3-like Stathmin PF00836.14 GAO85025.1 - 0.034 13.7 0.8 1.7 8.2 0.1 3.0 2 1 1 3 3 3 0 Stathmin family Hemerythrin PF01814.18 GAO85027.1 - 3.6e-15 56.2 2.4 5.3e-15 55.7 1.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Porphobil_deam PF01379.15 GAO85028.1 - 6.5e-77 257.2 0.0 1.1e-76 256.5 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAO85028.1 - 1.8e-20 72.7 0.3 5.6e-20 71.2 0.2 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain SMC_N PF02463.14 GAO85029.1 - 0.0021 17.3 0.3 0.0035 16.5 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Phage_holin_5 PF06946.6 GAO85030.1 - 3.1 8.0 4.7 2.3 8.4 2.1 1.8 1 1 0 1 1 1 0 Phage holin DUF2752 PF10825.3 GAO85033.1 - 0.0019 18.1 1.3 0.0029 17.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) DSBA PF01323.15 GAO85033.1 - 0.084 12.4 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain BTB PF00651.26 GAO85034.1 - 8.8e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-PARP PF00645.13 GAO85035.1 - 6.3e-24 84.0 0.1 6.3e-24 84.0 0.1 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Sec31 PF11549.3 GAO85035.1 - 2.6 7.7 0.0 2.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein transport protein SEC31 UQ_con PF00179.21 GAO85036.1 - 9.1e-25 86.7 0.0 2.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAO85036.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 GAO85036.1 - 0.024 14.3 0.1 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 UEV domain Cache_2 PF08269.6 GAO85036.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Cache domain DUF1168 PF06658.7 GAO85037.1 - 1.9e-47 160.3 21.1 2.7e-47 159.8 14.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4613 PF15390.1 GAO85037.1 - 0.65 8.1 4.5 0.86 7.7 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) NARP1 PF12569.3 GAO85037.1 - 2.6 6.6 17.1 3.4 6.3 11.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 GAO85037.1 - 3.2 5.3 9.6 3.3 5.3 6.7 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 GAO85037.1 - 6.8 4.2 10.6 7.1 4.1 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRI PF15325.1 GAO85037.1 - 8.5 7.3 12.0 21 6.1 8.3 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Cpn60_TCP1 PF00118.19 GAO85038.1 - 1e-164 548.7 0.0 1.2e-164 548.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2398 PF09661.5 GAO85039.1 - 0.045 12.4 0.3 0.07 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Lactamase_B_2 PF12706.2 GAO85040.1 - 1.9e-41 141.7 0.0 2.5e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO85040.1 - 8.6e-13 48.3 0.0 2e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAO85040.1 - 1.4e-07 31.4 0.3 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BCS1_N PF08740.6 GAO85041.1 - 9.6e-55 185.0 0.3 1.3e-54 184.6 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAO85041.1 - 1.8e-18 66.9 0.0 3.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAO85041.1 - 4.1e-05 24.3 0.1 0.00015 22.5 0.0 1.9 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 GAO85041.1 - 0.00044 20.2 0.1 0.0017 18.3 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 GAO85041.1 - 0.00055 18.9 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 GAO85041.1 - 0.00065 20.0 0.0 0.0026 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO85041.1 - 0.0011 19.1 0.0 0.0086 16.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAO85041.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 GAO85041.1 - 0.0043 17.0 0.1 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO85041.1 - 0.0044 16.8 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO85041.1 - 0.0063 16.2 0.0 0.023 14.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 GAO85041.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAO85041.1 - 0.014 15.6 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 GAO85041.1 - 0.016 15.5 0.0 0.049 13.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 GAO85041.1 - 0.043 13.0 0.0 0.23 10.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 KaiC PF06745.8 GAO85041.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 GAO85041.1 - 0.068 12.9 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 GAO85041.1 - 0.09 12.3 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAO85041.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein RuvB_N PF05496.7 GAO85041.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PPV_E1_C PF00519.12 GAO85041.1 - 0.13 10.8 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_11 PF13086.1 GAO85041.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAO85041.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Choline_transpo PF04515.7 GAO85043.1 - 9.7e-108 359.8 22.5 9.7e-108 359.8 15.6 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter p450 PF00067.17 GAO85044.1 - 2.3e-40 138.5 0.0 2.1e-39 135.3 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 GAO85045.1 - 8.4e-25 86.8 6.8 1.6e-24 85.9 4.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO85045.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Fungal_trans PF04082.13 GAO85046.1 - 1.5e-18 66.6 0.0 2.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85046.1 - 1.8e-08 34.1 8.3 3.8e-08 33.1 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Protein_K PF12283.3 GAO85046.1 - 0.092 12.6 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage protein K Trp_DMAT PF11991.3 GAO85047.1 - 1.5e-118 396.1 0.0 1.8e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 GAO85048.1 - 9.2e-153 508.5 0.0 1.7e-77 260.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO85048.1 - 7.4e-80 267.9 0.0 3.3e-45 154.2 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO85048.1 - 7.2e-24 83.8 0.0 3.3e-08 33.6 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO85048.1 - 1e-12 48.1 0.3 1.7e-08 34.6 0.0 3.4 2 1 1 3 3 3 2 HxxPF-repeated domain AMP-binding_C PF13193.1 GAO85048.1 - 1.3e-09 38.8 0.0 0.00075 20.4 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAO85048.1 - 0.069 11.5 0.1 0.84 8.0 0.0 2.2 2 0 0 2 2 2 0 Transferase family Methyltransf_2 PF00891.13 GAO85049.1 - 1.2e-33 116.3 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO85049.1 - 0.00089 19.0 0.0 0.0031 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85049.1 - 0.0023 18.5 0.0 0.0054 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 GAO85049.1 - 0.09 12.3 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MFS_1 PF07690.11 GAO85050.1 - 7.8e-27 93.9 44.6 1.5e-26 93.0 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAO85051.1 - 1.5e-07 31.2 10.8 1.5e-07 31.2 7.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Evr1_Alr PF04777.8 GAO85051.1 - 0.83 9.5 4.2 0.78 9.6 0.0 2.8 3 0 0 3 3 3 0 Erv1 / Alr family RabGAP-TBC PF00566.13 GAO85052.1 - 4.5e-38 130.8 0.6 6.4e-37 127.1 0.4 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.21 GAO85053.1 - 5.7e-42 142.4 0.0 6.4e-42 142.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO85053.1 - 3.8e-10 39.6 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO85053.1 - 0.024 14.5 0.3 0.034 14.0 0.2 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 GAO85053.1 - 0.052 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_S24 PF00717.18 GAO85054.1 - 3.2e-07 29.8 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like RTA1 PF04479.8 GAO85055.1 - 3.7e-17 62.5 3.5 6.6e-17 61.7 2.4 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.8 GAO85055.1 - 0.03 14.3 1.2 0.03 14.3 0.9 2.7 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) zf-DHHC PF01529.15 GAO85055.1 - 7.8 5.8 6.1 1.7 8.0 1.3 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase Kinesin PF00225.18 GAO85056.1 - 1.6e-57 194.7 0.0 2.6e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 GAO85056.1 - 0.0095 15.7 1.5 0.0095 15.7 1.0 3.5 3 1 1 4 4 4 1 Basic region leucine zipper KLRAQ PF10205.4 GAO85056.1 - 0.023 14.7 7.4 0.051 13.6 0.3 2.6 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF837 PF05769.6 GAO85056.1 - 0.12 11.8 6.9 0.57 9.6 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF837) IncA PF04156.9 GAO85056.1 - 0.22 11.1 11.4 1.6 8.3 5.3 2.3 2 0 0 2 2 2 0 IncA protein KIAA1430 PF13879.1 GAO85056.1 - 0.57 10.6 3.3 2.4 8.6 0.3 2.5 2 0 0 2 2 2 0 KIAA1430 homologue DivIC PF04977.10 GAO85056.1 - 0.65 9.5 3.8 4 7.0 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 GAO85056.1 - 2.7 8.0 7.5 18 5.3 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein TPR_11 PF13414.1 GAO85057.1 - 4.6e-06 26.1 8.8 0.0032 17.0 0.7 4.3 4 0 0 4 4 4 3 TPR repeat TPR_17 PF13431.1 GAO85057.1 - 0.28 11.4 2.8 50 4.4 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 GAO85058.1 - 2.6e-158 526.9 0.0 3.4e-158 526.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 GAO85058.1 - 1.4e-08 34.2 0.2 0.0065 16.0 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 GAO85058.1 - 5e-06 25.9 0.1 0.042 13.6 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO85058.1 - 1e-05 24.8 0.2 0.079 12.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85058.1 - 1.9e-05 24.2 3.1 0.0045 16.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO85058.1 - 2.7e-05 24.6 1.2 1.2 9.9 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85058.1 - 0.00013 22.3 4.7 2.8 8.8 0.0 4.7 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85058.1 - 0.00019 21.2 1.2 0.95 9.4 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO85058.1 - 0.00049 20.1 0.1 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAO85058.1 - 0.0037 17.5 0.3 5 7.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAO85058.1 - 0.0067 15.5 1.0 0.17 10.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85058.1 - 0.0073 16.0 0.7 2.4 8.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAO85058.1 - 0.034 13.9 0.1 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Antimicrobial_8 PF08103.6 GAO85058.1 - 0.37 10.8 2.3 2.1 8.4 0.3 2.9 2 0 0 2 2 2 0 Uperin family Fungal_trans PF04082.13 GAO85060.1 - 1.2e-07 30.8 0.6 3e-07 29.5 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85060.1 - 9.2e-06 25.4 11.2 1.6e-05 24.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 GAO85061.1 - 4.7e-21 75.3 0.0 6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO85061.1 - 1.7e-12 46.6 0.0 2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO85061.1 - 2.6e-08 33.1 0.0 0.00029 19.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 GAO85061.1 - 3.9e-07 29.2 0.0 1.3e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAO85061.1 - 4.3e-07 30.0 0.0 3.3e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO85061.1 - 6.4e-07 29.5 0.0 9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO85061.1 - 0.0013 18.4 0.0 0.033 13.8 0.0 2.3 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAO85061.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.4 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO85061.1 - 0.079 11.8 0.0 0.35 9.7 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 GAO85061.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3292 PF11696.3 GAO85062.1 - 0 1188.0 0.0 0 1187.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF639 PF04842.7 GAO85062.1 - 0.13 10.3 0.3 0.2 9.7 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) ERCC4 PF02732.10 GAO85063.1 - 1.1e-32 112.7 0.1 1.9e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 GAO85063.1 - 0.0027 17.8 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain E1-E2_ATPase PF00122.15 GAO85064.1 - 3.2e-56 189.9 0.0 9.1e-55 185.1 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 GAO85064.1 - 1.2e-47 159.8 0.1 2.9e-12 46.5 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 GAO85064.1 - 1.7e-34 120.1 0.1 3.3e-34 119.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO85064.1 - 2.6e-17 63.6 0.0 4.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO85064.1 - 1.3e-06 28.1 0.6 0.00035 20.2 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase TFIIB PF00382.14 GAO85065.1 - 3.5e-34 116.4 1.4 5e-18 64.6 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 GAO85065.1 - 7.2e-28 96.6 2.3 2e-27 95.2 0.0 2.7 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 GAO85065.1 - 2e-06 27.3 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 GAO85065.1 - 0.00028 20.1 2.2 0.00064 18.9 1.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 GAO85065.1 - 0.015 14.7 0.2 0.034 13.6 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 GAO85065.1 - 0.02 14.7 1.2 0.039 13.8 0.8 1.4 1 0 0 1 1 1 0 IBR domain DUF2249 PF10006.4 GAO85065.1 - 0.078 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Sugar_tr PF00083.19 GAO85066.1 - 1.1e-84 284.6 22.4 1.4e-84 284.2 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85066.1 - 3e-23 82.1 25.3 6.3e-23 81.0 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Preseq_ALAS PF09029.5 GAO85067.1 - 0.0044 16.9 0.2 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 5-aminolevulinate synthase presequence TPT PF03151.11 GAO85068.1 - 2.5e-27 95.3 15.5 2.5e-27 95.3 10.8 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAO85068.1 - 9.3e-05 21.4 24.7 0.0021 17.0 4.6 2.3 2 0 0 2 2 2 2 UAA transporter family NAD_binding_8 PF13450.1 GAO85069.1 - 1.6e-09 37.6 0.0 6.3e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAO85069.1 - 7e-07 28.6 0.0 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAO85069.1 - 1.8e-05 24.9 0.2 0.00011 22.3 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO85069.1 - 0.0043 16.9 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO85069.1 - 0.0062 15.6 0.1 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF1344 PF07076.6 GAO85069.1 - 0.013 15.0 0.5 0.031 13.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Thi4 PF01946.12 GAO85069.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAO85069.1 - 0.046 13.5 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO85069.1 - 0.049 12.0 0.0 0.08 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 GAO85069.1 - 0.089 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 GAO85069.1 - 0.089 11.6 0.1 0.2 10.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO85069.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO85069.1 - 0.17 10.7 0.3 0.37 9.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pkinase PF00069.20 GAO85071.1 - 9.9e-66 221.5 0.0 1.4e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85071.1 - 1.1e-31 109.8 0.0 8e-31 107.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85071.1 - 0.00037 19.5 0.0 0.0012 17.8 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAO85071.1 - 0.00037 19.6 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO85071.1 - 0.035 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 GAO85072.1 - 1.2e-29 103.1 2.0 2.9e-29 101.8 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85072.1 - 1.8e-06 27.7 7.3 3.3e-06 26.8 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.26 GAO85073.1 - 0.0082 16.1 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain tRNA-synt_2b PF00587.20 GAO85074.1 - 5.4e-21 74.9 0.0 7.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAO85074.1 - 2.7e-09 37.0 2.8 4.7e-09 36.2 2.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 GAO85074.1 - 0.00042 19.3 0.2 0.00056 18.9 0.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 GAO85074.1 - 0.0033 17.2 2.2 0.0062 16.3 1.5 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF342 PF03961.8 GAO85074.1 - 0.0046 15.4 1.5 0.0069 14.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) GAS PF13851.1 GAO85074.1 - 0.0051 16.0 2.0 0.0051 16.0 1.4 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 GAO85074.1 - 0.0077 15.9 3.7 0.013 15.1 2.6 1.2 1 0 0 1 1 1 1 Mnd1 family FUSC PF04632.7 GAO85074.1 - 0.01 14.3 1.0 0.015 13.8 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WXG100 PF06013.7 GAO85074.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG bZIP_1 PF00170.16 GAO85074.1 - 0.029 14.3 2.3 4.1 7.4 0.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor Spectrin PF00435.16 GAO85074.1 - 0.03 14.5 1.2 0.058 13.6 0.9 1.4 1 0 0 1 1 1 0 Spectrin repeat IncA PF04156.9 GAO85074.1 - 0.034 13.7 5.4 0.058 12.9 3.7 1.3 1 0 0 1 1 1 0 IncA protein GOLGA2L5 PF15070.1 GAO85074.1 - 0.035 12.6 0.7 0.05 12.0 0.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF904 PF06005.7 GAO85074.1 - 0.039 14.2 0.4 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ERM PF00769.14 GAO85074.1 - 0.048 13.2 4.0 0.081 12.4 2.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6 PF04111.7 GAO85074.1 - 0.053 12.5 0.9 0.083 11.9 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 GAO85074.1 - 0.074 13.0 10.2 0.19 11.7 0.8 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 GAO85074.1 - 0.16 11.4 2.7 0.69 9.4 1.9 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LCD1 PF09798.4 GAO85074.1 - 0.21 9.5 0.1 0.3 9.0 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CENP-F_leu_zip PF10473.4 GAO85074.1 - 0.35 10.7 6.4 1.2 8.9 0.3 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 GAO85074.1 - 0.35 10.8 2.5 3.4 7.6 0.1 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TMF_DNA_bd PF12329.3 GAO85074.1 - 0.4 10.5 6.5 1.3 8.8 3.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4164 PF13747.1 GAO85074.1 - 0.4 10.8 6.2 0.89 9.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DivIC PF04977.10 GAO85074.1 - 0.41 10.1 4.8 4.3 6.9 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 GAO85074.1 - 0.85 10.1 6.0 11 6.5 0.2 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 GAO85074.1 - 1.2 8.9 6.3 7.1 6.3 0.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cytochrom_B561 PF03188.11 GAO85075.1 - 5.8e-14 52.0 2.1 5.8e-14 52.0 1.5 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF3999 PF13163.1 GAO85075.1 - 0.025 13.5 0.2 0.033 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) DUF2427 PF10348.4 GAO85075.1 - 0.17 11.4 4.8 0.062 12.8 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) DUF4231 PF14015.1 GAO85075.1 - 2.9 7.9 10.2 13 5.7 4.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) AAT PF03417.11 GAO85076.1 - 2.6e-19 69.5 0.0 5.4e-19 68.5 0.0 1.5 2 1 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAO85076.1 - 9.4e-06 25.8 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Alpha-amylase PF00128.19 GAO85076.1 - 0.035 13.5 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Glyco_hydro_1 PF00232.13 GAO85078.1 - 1.3e-149 498.2 0.9 1.6e-149 498.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.1 GAO85079.1 - 4.7e-63 213.0 0.0 6.2e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 GAO85080.1 - 6.5e-58 196.3 29.3 8.1e-58 196.0 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85080.1 - 1.5e-20 73.2 32.5 1.9e-20 72.8 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily EzrA PF06160.7 GAO85081.1 - 0.027 12.6 1.0 0.03 12.5 0.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LTXXQ PF07813.7 GAO85081.1 - 0.035 14.5 1.0 0.044 14.2 0.7 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein Spectrin PF00435.16 GAO85081.1 - 0.048 13.9 3.2 0.77 10.0 2.2 2.1 1 1 0 1 1 1 0 Spectrin repeat DUF2508 PF10704.4 GAO85081.1 - 0.064 13.4 0.4 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Cytochrome_CBB3 PF13442.1 GAO85081.1 - 0.077 13.1 0.1 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF641 PF04859.7 GAO85081.1 - 0.18 11.5 2.6 0.29 10.8 1.7 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Allantoicase PF03561.10 GAO85082.1 - 1.2e-82 274.8 0.0 1.8e-44 150.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 GAO85083.1 - 7.6e-30 102.9 0.0 3.1e-29 100.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO85083.1 - 2.6e-21 75.7 0.3 1.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAO85083.1 - 6.6e-20 70.8 0.0 1.9e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 GAO85083.1 - 1.5e-13 51.4 0.0 3.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 GAO85083.1 - 2.5e-11 43.9 3.2 4.6e-11 43.0 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain GAF_3 PF13492.1 GAO85083.1 - 6.5e-08 32.7 0.0 2e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 GAO85083.1 - 1.4e-07 31.8 0.0 2.1e-05 24.6 0.0 2.8 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 GAO85083.1 - 7.6e-07 28.5 0.0 4.3e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain NB-ARC PF00931.17 GAO85083.1 - 1e-05 24.5 0.0 0.053 12.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.7 GAO85083.1 - 2.2e-05 24.1 0.1 0.34 10.5 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 GAO85083.1 - 0.00024 21.2 0.1 1.3 9.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain TPR_8 PF13181.1 GAO85083.1 - 0.0029 17.2 0.1 0.027 14.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85083.1 - 0.0078 16.0 0.4 56 4.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HATPase_c_3 PF13589.1 GAO85083.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.23 GAO85083.1 - 0.024 14.2 0.1 14 5.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85083.1 - 0.027 14.3 5.2 0.41 10.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF258 PF03193.11 GAO85083.1 - 0.074 12.2 0.0 0.21 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_4 PF07721.9 GAO85083.1 - 0.13 12.7 3.8 0.3 11.6 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Response_reg PF00072.19 GAO85084.1 - 1.6e-22 79.6 0.0 3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAO85084.1 - 3.5e-22 78.2 0.1 8.4e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAO85084.1 - 4.5e-18 65.0 0.1 1.6e-17 63.2 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 GAO85084.1 - 1.5e-14 53.8 0.4 4.2e-05 23.5 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 GAO85084.1 - 1.9e-12 47.4 0.0 7e-08 32.7 0.0 3.9 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 GAO85084.1 - 2e-08 34.2 0.1 1.6e-06 28.0 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 GAO85084.1 - 8.9e-05 22.2 0.0 0.033 13.9 0.0 3.0 2 0 0 2 2 2 1 PAS fold MotA_ExbB PF01618.11 GAO85084.1 - 0.12 11.9 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family KxDL PF10241.4 GAO85085.1 - 3.9e-36 122.8 0.3 5e-36 122.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein Nol1_Nop2_Fmu_2 PF13636.1 GAO85085.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis AAA PF00004.24 GAO85086.1 - 2.5e-51 173.3 0.0 2.6e-38 131.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAO85086.1 - 1.9e-14 53.3 0.0 4.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 GAO85086.1 - 3.7e-14 52.1 0.1 1.1e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 GAO85086.1 - 1.3e-08 35.0 0.4 0.00073 19.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAO85086.1 - 1.1e-07 31.8 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAO85086.1 - 1.9e-07 31.1 0.0 2.7e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAO85086.1 - 2.1e-07 31.8 0.0 0.003 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO85086.1 - 3.9e-07 30.2 0.1 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 GAO85086.1 - 2.6e-06 27.7 0.0 0.0046 17.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 GAO85086.1 - 3.3e-06 26.7 0.8 0.022 14.5 0.1 3.2 3 0 0 3 3 3 2 Part of AAA domain TIP49 PF06068.8 GAO85086.1 - 5.3e-06 25.4 0.1 0.015 13.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 GAO85086.1 - 5.5e-06 26.3 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAO85086.1 - 1.4e-05 24.3 0.1 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO85086.1 - 1.9e-05 24.3 0.0 0.0012 18.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAO85086.1 - 2.1e-05 23.6 0.0 0.041 12.9 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 GAO85086.1 - 0.00032 20.4 1.5 8.9 5.9 0.0 4.1 2 2 1 4 4 4 0 Archaeal ATPase IstB_IS21 PF01695.12 GAO85086.1 - 0.00038 19.9 0.8 0.04 13.3 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAO85086.1 - 0.00045 19.3 0.0 0.37 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 GAO85086.1 - 0.00046 20.3 0.0 0.096 12.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 GAO85086.1 - 0.0015 18.0 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 GAO85086.1 - 0.003 17.0 2.7 0.49 9.7 0.0 3.7 2 2 2 4 4 4 1 AAA domain ABC_tran PF00005.22 GAO85086.1 - 0.0036 17.5 0.3 0.043 14.1 0.1 2.4 2 0 0 2 2 2 1 ABC transporter KaiC PF06745.8 GAO85086.1 - 0.0051 15.9 0.4 0.022 13.8 0.1 2.1 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 GAO85086.1 - 0.0057 15.9 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.7 GAO85086.1 - 0.006 16.2 0.0 4.4 6.9 0.0 3.1 2 1 0 2 2 2 0 NACHT domain DEAD PF00270.24 GAO85086.1 - 0.0064 15.9 0.5 5.6 6.4 0.0 3.9 2 2 1 4 4 4 0 DEAD/DEAH box helicase UPF0079 PF02367.12 GAO85086.1 - 0.0075 15.8 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 GAO85086.1 - 0.009 15.9 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain IPT PF01745.11 GAO85086.1 - 0.013 14.6 0.1 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 GAO85086.1 - 0.014 14.3 0.0 4.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 GAO85086.1 - 0.016 14.0 0.1 1.3 7.8 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 GAO85086.1 - 0.037 12.9 0.0 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 GAO85086.1 - 0.053 13.1 3.7 0.12 11.9 0.1 2.9 3 1 0 3 3 3 0 AAA domain KTI12 PF08433.5 GAO85086.1 - 0.15 11.2 0.0 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 GAO85086.1 - 0.17 10.8 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cir_N PF10197.4 GAO85087.1 - 0.0066 16.4 5.1 0.0066 16.4 3.5 3.7 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_31 PF13847.1 GAO85088.1 - 7.8e-11 41.7 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO85088.1 - 2e-08 33.7 0.0 4.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAO85088.1 - 5.1e-08 33.4 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85088.1 - 5.5e-08 33.1 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO85088.1 - 3.4e-06 27.0 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO85088.1 - 2.6e-05 24.0 0.0 5.8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO85088.1 - 4.6e-05 22.8 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAO85088.1 - 0.00055 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAO85088.1 - 0.0033 16.1 0.3 0.0065 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 GAO85088.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 GAO85088.1 - 0.021 13.7 0.0 0.062 12.2 0.0 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 GAO85088.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 GAO85088.1 - 0.029 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 GAO85088.1 - 0.031 13.8 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 GAO85088.1 - 0.053 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 GAO85088.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 GAO85088.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 GAO85088.1 - 0.085 13.6 0.0 0.37 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Mo25 PF08569.6 GAO85089.1 - 3.2e-137 457.0 0.1 3.6e-137 456.9 0.1 1.0 1 0 0 1 1 1 1 Mo25-like RabGAP-TBC PF00566.13 GAO85090.1 - 6.9e-34 117.2 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.14 GAO85092.1 - 6e-19 67.8 2.4 7e-12 45.1 0.2 2.5 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 GAO85092.1 - 9.8e-19 67.4 0.1 4.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO85092.1 - 2.8e-16 58.4 0.1 5e-07 29.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAO85092.1 - 4.6e-14 52.1 0.0 7.7e-08 32.3 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO85092.1 - 1.3e-10 41.5 0.2 5.9e-05 23.4 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO85092.1 - 1.4e-08 34.1 0.4 0.0048 17.0 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat RasGEF PF00617.14 GAO85093.1 - 4.9e-45 153.5 0.1 7.5e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAO85093.1 - 3.3e-14 52.8 0.1 6.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.8 GAO85094.1 - 7.7e-87 291.8 0.0 1.2e-86 291.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 GAO85094.1 - 8.8e-55 185.0 0.0 1.3e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 G-alpha PF00503.15 GAO85095.1 - 3.8e-114 381.3 0.1 4.2e-114 381.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAO85095.1 - 7.6e-14 51.3 0.6 3.8e-09 36.0 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAO85095.1 - 1.5e-06 27.5 0.0 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO85095.1 - 0.012 16.0 0.0 0.75 10.3 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 GAO85095.1 - 0.018 14.9 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 GAO85095.1 - 0.033 13.7 0.1 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 GAO85095.1 - 0.051 12.9 0.0 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 GAO85095.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1713 PF08213.6 GAO85096.1 - 1.2e-12 47.2 20.7 2.3e-12 46.2 14.4 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 GAO85096.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein Pet20 ATP-synt_C PF00137.16 GAO85097.1 - 1.5e-31 108.0 30.1 2.7e-17 62.4 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 GAO85097.1 - 0.47 10.0 4.4 0.15 11.6 0.9 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 GAO85097.1 - 6.6 6.4 8.8 1.3 8.6 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1517 PF07466.6 GAO85099.1 - 7.7 5.4 6.2 1.4 7.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1517) Hydrolase_6 PF13344.1 GAO85100.1 - 9.3e-23 80.0 0.0 1.9e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO85100.1 - 3.3e-12 45.9 0.1 1.2e-10 40.9 0.0 3.3 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 GAO85100.1 - 0.039 14.1 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Lipase_3 PF01764.20 GAO85100.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 GAO85101.1 - 1.9e-47 161.3 0.0 3.1e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAO85101.1 - 1.4e-08 34.9 0.1 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85101.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO85101.1 - 0.00064 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 GAO85101.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_L22e PF01776.12 GAO85103.1 - 2.3e-49 166.0 0.6 2.8e-49 165.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DIM1 PF02966.11 GAO85104.1 - 2.6e-69 230.8 0.2 2.9e-69 230.6 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 GAO85104.1 - 0.15 12.2 0.6 0.63 10.2 0.4 1.8 1 1 1 2 2 2 0 Thioredoxin-like Translin PF01997.11 GAO85105.1 - 2.6e-49 167.5 0.0 3.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 GAO85105.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 GMP synthase C terminal domain GSHPx PF00255.14 GAO85106.1 - 3.9e-39 132.3 0.0 5.3e-39 131.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 GAO85106.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 GAO85106.1 - 0.017 14.6 0.2 0.028 13.9 0.1 1.6 1 1 0 1 1 1 0 Redoxin SCO1-SenC PF02630.9 GAO85106.1 - 0.035 13.7 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 SCO1/SenC Pcc1 PF09341.5 GAO85107.1 - 3.8e-27 94.1 0.3 4.7e-27 93.8 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Baculo_PEP_C PF04513.7 GAO85108.1 - 0.058 13.2 6.0 0.51 10.1 3.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CsbD PF05532.7 GAO85108.1 - 0.19 11.4 2.2 0.61 9.8 0.4 2.6 1 1 1 2 2 2 0 CsbD-like DSPn PF14671.1 GAO85109.1 - 1.1e-45 155.1 0.0 9.8e-43 145.5 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 GAO85109.1 - 2.5e-16 59.4 0.0 1e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAO85109.1 - 1.7e-06 27.5 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LptE PF04390.7 GAO85109.1 - 0.012 15.4 0.9 0.021 14.5 0.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Y_phosphatase2 PF03162.8 GAO85109.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAO85109.1 - 0.15 12.3 0.4 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Myc_N PF01056.13 GAO85109.1 - 1.6 7.8 11.3 3.2 6.8 3.3 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Zn_clus PF00172.13 GAO85111.1 - 2.3e-09 37.0 8.4 4.7e-09 35.9 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO85111.1 - 1.2e-08 34.0 4.3 2.3e-08 33.0 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.22 GAO85112.1 - 7.1e-41 139.7 0.1 4.1e-27 95.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO85112.1 - 2.8e-12 47.2 0.0 3.3e-05 24.0 0.2 3.2 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAO85112.1 - 1.8e-11 43.6 0.3 0.00043 19.5 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 GAO85112.1 - 2.4e-10 40.2 3.3 4.6e-10 39.3 2.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.1 GAO85112.1 - 0.0046 17.1 0.8 0.046 13.8 0.4 2.5 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 GAO85112.1 - 0.017 14.9 0.2 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 GAO85112.1 - 0.021 14.2 0.5 3.9 6.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 GAO85112.1 - 0.024 14.8 0.3 0.19 11.9 0.1 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAO85112.1 - 0.031 13.6 0.0 0.031 13.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 GAO85112.1 - 0.041 12.7 1.6 4.2 6.1 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.1 GAO85112.1 - 0.042 13.7 0.2 1.3 8.9 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 GAO85112.1 - 0.073 12.7 0.2 0.41 10.3 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 GAO85112.1 - 0.084 11.9 0.6 0.34 9.9 0.0 2.2 2 1 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 GAO85112.1 - 0.085 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 GAO85112.1 - 0.14 11.8 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 GAO85112.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO85112.1 - 0.16 12.2 0.3 0.74 10.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 GAO85112.1 - 0.17 11.1 0.3 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.1 GAO85112.1 - 0.53 10.2 2.9 0.6 10.0 0.4 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 GAO85112.1 - 0.99 7.7 1.5 5.2 5.4 0.1 2.1 1 1 1 2 2 2 0 AAA domain OPT PF03169.10 GAO85113.1 - 2.4e-140 468.9 45.8 1.8e-71 241.4 13.0 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein zf-RING_2 PF13639.1 GAO85114.1 - 7.6e-12 44.8 8.1 1.2e-11 44.2 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAO85114.1 - 8.8e-07 28.4 5.9 1.7e-06 27.5 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO85114.1 - 2.5e-06 27.3 6.5 4.3e-06 26.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO85114.1 - 9e-05 22.1 5.9 0.00014 21.4 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAO85114.1 - 0.00012 22.1 8.0 0.00025 21.0 5.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAO85114.1 - 0.00022 20.8 3.6 0.00035 20.1 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO85114.1 - 0.001 18.7 3.6 0.0021 17.7 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 GAO85114.1 - 0.0029 17.3 2.5 0.0046 16.7 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rax2 PF12768.2 GAO85114.1 - 0.0057 15.8 0.0 0.0073 15.5 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.7 GAO85114.1 - 0.0094 15.3 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor RINGv PF12906.2 GAO85114.1 - 0.01 15.8 4.6 0.026 14.5 3.2 1.7 1 1 0 1 1 1 0 RING-variant domain TMEM154 PF15102.1 GAO85114.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 GAO85114.1 - 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 GAO85114.1 - 0.032 13.6 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SKG6 PF08693.5 GAO85114.1 - 0.053 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.6 GAO85114.1 - 0.068 12.8 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin zf-RING_4 PF14570.1 GAO85114.1 - 0.11 12.0 4.8 0.31 10.6 3.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MscS_TM PF12794.2 GAO85114.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4448 PF14610.1 GAO85114.1 - 0.25 10.7 0.9 0.72 9.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) FANCL_C PF11793.3 GAO85114.1 - 0.39 10.7 7.5 3.6 7.6 5.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 GAO85114.1 - 0.66 10.0 5.1 1.1 9.2 3.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 GAO85114.1 - 0.85 9.5 6.8 15 5.6 4.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.24 GAO85114.1 - 5.5 6.7 7.8 27 4.5 5.7 2.0 1 1 1 2 2 2 0 PHD-finger Fungal_trans PF04082.13 GAO85115.1 - 3.3e-09 36.0 0.0 6.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 GAO85116.1 - 4.2e-07 29.5 0.2 9.3e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 GAO85117.1 - 1.5e-38 132.5 33.1 8.3e-22 77.3 8.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO85117.1 - 7.3e-23 80.8 37.2 2.1e-22 79.3 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MSC PF09402.5 GAO85117.1 - 0.14 10.8 0.5 0.21 10.2 0.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PhyH PF05721.8 GAO85118.1 - 2.2e-25 89.9 0.0 3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 GAO85118.1 - 2.8e-05 24.5 0.0 4.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 GAO85118.1 - 0.00014 22.0 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase HD PF01966.17 GAO85119.1 - 1.9e-10 40.8 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 GAO85119.1 - 1.2e-05 24.6 0.1 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 GAO85119.1 - 0.00015 21.2 0.1 0.0002 20.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD_4 PF13328.1 GAO85119.1 - 0.014 15.0 0.3 0.024 14.3 0.2 1.4 1 1 0 1 1 1 0 HD domain Sugar_tr PF00083.19 GAO85120.1 - 7.7e-94 314.8 28.2 8.7e-94 314.6 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85120.1 - 4.8e-30 104.4 51.3 2.8e-24 85.4 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO85120.1 - 0.00055 18.2 2.8 0.00055 18.2 2.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Homeobox PF00046.24 GAO85121.1 - 6.8e-14 51.2 0.1 2.2e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Amino_oxidase PF01593.19 GAO85122.1 - 4.7e-45 154.5 0.1 1.2e-27 97.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO85122.1 - 4.1e-15 55.5 0.2 8e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO85122.1 - 1e-07 32.2 0.2 2.1e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO85122.1 - 7e-05 22.9 0.5 0.0002 21.4 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO85122.1 - 7.3e-05 22.7 0.5 0.00038 20.4 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO85122.1 - 0.00013 21.0 0.0 0.00064 18.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO85122.1 - 0.00016 20.2 0.2 0.00025 19.6 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAO85122.1 - 0.00023 20.3 0.2 0.00037 19.6 0.2 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAO85122.1 - 0.00026 20.7 0.4 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAO85122.1 - 0.00043 19.2 0.4 0.00077 18.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAO85122.1 - 0.00088 18.4 0.4 0.0013 17.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 GAO85122.1 - 0.013 15.2 0.2 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO85122.1 - 0.016 14.7 0.4 0.029 13.9 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 GAO85122.1 - 0.033 13.0 0.3 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAO85122.1 - 0.034 13.2 0.4 0.049 12.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAO85122.1 - 0.048 13.0 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 GAO85122.1 - 0.084 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 GAO85122.1 - 0.13 12.0 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 GAO85122.1 - 0.15 12.0 0.5 0.29 11.0 0.4 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF2235 PF09994.4 GAO85124.1 - 7.1e-112 373.3 0.1 1.1e-111 372.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CaMBD PF02888.11 GAO85124.1 - 0.11 12.3 2.2 9.4 6.1 0.2 2.8 2 0 0 2 2 2 0 Calmodulin binding domain An_peroxidase PF03098.10 GAO85125.1 - 1.6e-94 317.2 0.0 2.7e-92 309.8 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAO85125.1 - 0.00056 18.5 0.1 0.029 12.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Hexapep PF00132.19 GAO85126.1 - 9.8e-09 34.3 7.9 0.00018 20.8 2.0 4.5 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAO85126.1 - 9.5e-05 21.8 4.9 0.0002 20.8 0.3 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAO85126.1 - 0.059 11.9 0.0 0.083 11.4 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Glycos_transf_1 PF00534.15 GAO85127.1 - 7.2e-19 67.8 0.0 2.2e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO85127.1 - 2.7e-08 34.0 0.0 1.3e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAO85127.1 - 5.1e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF823 PF05689.6 GAO85127.1 - 0.068 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Arf PF00025.16 GAO85128.1 - 1.3e-71 239.4 0.1 1.5e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAO85128.1 - 1.7e-13 50.2 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAO85128.1 - 6.6e-13 48.0 1.3 1.4e-09 37.1 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAO85128.1 - 6.6e-11 41.7 0.0 8e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAO85128.1 - 8.3e-10 38.1 0.0 9.5e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO85128.1 - 2.2e-07 31.4 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAO85128.1 - 0.00012 22.0 0.1 0.0002 21.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO85128.1 - 0.00067 19.1 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 GAO85128.1 - 0.011 14.7 0.2 0.027 13.5 0.1 1.5 1 1 1 2 2 2 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 GAO85128.1 - 0.023 13.9 0.5 0.039 13.2 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2945 PF11160.3 GAO85129.1 - 6.9e-24 83.4 0.3 7.7e-24 83.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) DUF3673 PF12425.3 GAO85129.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) Meth_synt_2 PF01717.13 GAO85130.1 - 8.4e-18 64.4 0.0 1.8e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAO85130.1 - 2.5e-06 26.9 0.1 0.00069 18.9 0.0 3.1 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 GAO85131.1 - 0.13 12.0 5.2 0.097 12.4 0.9 2.7 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 GAO85131.1 - 0.54 9.9 5.7 0.62 9.7 0.1 3.1 3 0 0 3 3 3 0 F-box domain PHD PF00628.24 GAO85133.1 - 1.2e-11 44.0 8.3 2.7e-11 42.9 5.7 1.6 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 GAO85133.1 - 9.2e-05 22.2 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Neuropep_like PF15161.1 GAO85133.1 - 0.026 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Neuropeptide-like Fungal_trans_2 PF11951.3 GAO85134.1 - 0.00019 20.1 0.0 0.00032 19.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_r2 PF04542.9 GAO85134.1 - 0.0011 18.5 0.9 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sugar_tr PF00083.19 GAO85135.1 - 7.4e-109 364.3 20.3 8.4e-109 364.1 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85135.1 - 8.9e-28 97.0 29.4 8.9e-28 97.0 20.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO85135.1 - 0.0027 15.9 2.7 0.0027 15.9 1.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAO85136.1 - 1.8e-28 99.1 0.0 3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 GAO85136.1 - 0.0048 16.8 0.7 0.025 14.4 0.1 2.3 2 0 0 2 2 2 1 Gal4-like dimerisation domain DUF4446 PF14584.1 GAO85136.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) 2OG-FeII_Oxy_3 PF13640.1 GAO85137.1 - 6.1e-05 23.4 0.2 0.00032 21.1 0.2 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAO85137.1 - 0.00032 20.9 0.0 0.0058 16.8 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAO85137.1 - 0.00064 19.3 0.3 0.0013 18.3 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2 PF00096.21 GAO85138.1 - 1.1e-05 25.4 18.0 1.8e-05 24.7 1.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO85138.1 - 5.1e-05 23.3 3.8 5.1e-05 23.3 2.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO85138.1 - 0.0012 19.0 0.9 0.0012 19.0 0.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO85138.1 - 0.0014 18.6 0.7 0.0036 17.3 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 GAO85138.1 - 0.18 12.2 7.7 0.13 12.6 1.5 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger Fork_head PF00250.13 GAO85139.1 - 1.3e-37 127.6 1.9 2.4e-37 126.8 1.3 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAO85139.1 - 6.3e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.11 GAO85140.1 - 1.4e-15 57.6 0.0 5.2e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 TENA/THI-4/PQQC family Ras PF00071.17 GAO85141.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Ras family HemX PF04375.9 GAO85141.1 - 0.12 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HemX PHD PF00628.24 GAO85143.1 - 1.4e-08 34.2 10.6 2.7e-08 33.3 7.4 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 GAO85143.1 - 2.2e-08 34.3 0.0 3.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF3356 PF11836.3 GAO85143.1 - 0.064 13.0 3.2 8.5 6.2 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3356) Glyco_hydro_67C PF07477.7 GAO85143.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus zf-RING-like PF08746.6 GAO85143.1 - 2.6 8.1 7.8 8.2 6.5 5.1 2.0 1 1 1 2 2 2 0 RING-like domain GFO_IDH_MocA PF01408.17 GAO85144.1 - 1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 GAO85145.1 - 3.7e-37 127.5 0.0 2.4e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 GAO85145.1 - 0.049 13.7 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix AP_endonuc_2 PF01261.19 GAO85145.1 - 0.052 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ADH_N PF08240.7 GAO85146.1 - 7.6e-27 93.2 4.0 1.3e-26 92.4 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO85146.1 - 1.8e-17 63.0 0.0 3.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO85146.1 - 1.2e-05 24.5 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 GAO85146.1 - 0.0056 16.1 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF4112 PF13430.1 GAO85147.1 - 0.018 14.9 0.1 0.043 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Transferrin PF00405.12 GAO85147.1 - 0.056 12.3 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Transferrin WD40 PF00400.27 GAO85148.1 - 2.5e-43 144.4 10.4 1.7e-10 40.3 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 GAO85148.1 - 6.5e-11 41.7 0.5 1.4e-10 40.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO85148.1 - 0.00022 20.7 0.1 0.00046 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAO85148.1 - 0.064 12.7 0.6 0.38 10.1 0.4 2.1 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.16 GAO85148.1 - 0.076 12.5 0.0 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Cytochrom_D1 PF02239.11 GAO85148.1 - 0.1 10.8 0.3 0.23 9.7 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain EB1 PF03271.12 GAO85149.1 - 2.3e-16 59.5 0.6 4.2e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 GAO85149.1 - 3.9e-06 26.8 0.7 5.6e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 GAO85149.1 - 0.048 11.8 0.0 0.076 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Phi-29_GP3 PF05435.6 GAO85149.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 DUF3355 PF11835.3 GAO85149.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) GFO_IDH_MocA PF01408.17 GAO85151.1 - 1.9e-13 50.9 0.0 4.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO85151.1 - 3.4e-05 23.6 0.1 8.9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 GAO85152.1 - 1.7e-32 111.7 0.0 2.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAO85152.1 - 3.9e-25 88.0 0.0 7.6e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAO85152.1 - 3.1e-16 59.5 0.1 8.3e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAO85152.1 - 5.9e-10 39.0 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 GAO85153.1 - 7.4e-26 91.3 0.0 8.4e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Med5 PF08689.5 GAO85154.1 - 1.7 6.2 5.7 2.4 5.7 3.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 BTV_NS2 PF04514.7 GAO85154.1 - 5.9 5.6 9.2 0.75 8.6 1.4 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Ank_3 PF13606.1 GAO85155.1 - 0.005 16.9 0.0 0.034 14.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 GAO85155.1 - 0.0072 16.5 0.0 0.064 13.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 GAO85155.1 - 0.052 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat SSP160 PF06933.6 GAO85155.1 - 0.21 9.5 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 JmjC PF02373.17 GAO85156.1 - 1.8e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PhoU_div PF01865.11 GAO85156.1 - 0.0014 17.8 0.1 0.0025 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF47 2OG-FeII_Oxy_5 PF13759.1 GAO85156.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.6 GAO85156.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Sugar_tr PF00083.19 GAO85157.1 - 4.9e-91 305.5 22.6 6.7e-91 305.1 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85157.1 - 4.4e-14 51.9 43.7 1.5e-09 37.0 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 GAO85158.1 - 5.8e-69 232.3 0.0 7.8e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 GAO85158.1 - 1.1e-17 63.8 0.0 4.7e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO85158.1 - 2.1e-17 62.9 0.0 8.1e-08 32.1 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO85158.1 - 7.9e-11 42.1 0.0 8.5e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO85158.1 - 3.2e-10 39.9 0.0 9e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 GAO85158.1 - 1.4e-07 31.5 0.0 0.011 15.7 0.0 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 GAO85158.1 - 1.5e-05 24.5 0.0 4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_CG PF14542.1 GAO85158.1 - 0.0028 17.5 0.0 1.4 8.8 0.0 2.9 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 GAO85158.1 - 0.03 14.4 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO85158.1 - 0.032 14.0 0.0 5.1 6.9 0.0 2.8 2 0 0 2 2 2 0 FR47-like protein ATG22 PF11700.3 GAO85159.1 - 2.5e-85 286.7 17.2 8e-39 133.4 3.7 3.2 1 1 2 3 3 3 3 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAO85159.1 - 4.5e-05 22.3 1.5 4.5e-05 22.3 1.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 GAO85160.1 - 1.4e-40 139.1 33.7 1.4e-40 139.1 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO85160.1 - 1.4e-08 33.7 13.7 1.4e-08 33.7 9.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO85160.1 - 3.1e-06 25.6 1.8 4.6e-06 25.1 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Oxysterol_BP PF01237.13 GAO85161.1 - 8.8e-91 304.0 0.2 1.1e-90 303.7 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein CUE PF02845.11 GAO85162.1 - 8.3e-11 41.1 0.0 1.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ubiq_cyt_C_chap PF03981.7 GAO85163.1 - 0.029 14.2 0.2 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone AlaDh_PNT_N PF05222.10 GAO85165.1 - 4.7e-30 104.3 0.0 7.1e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 GAO85165.1 - 6e-20 71.4 0.0 9.5e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 GAO85165.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UCH PF00443.24 GAO85166.1 - 2.7e-42 144.7 0.1 1.5e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO85166.1 - 2.4e-12 46.9 0.1 8.5e-09 35.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 GAO85166.1 - 0.19 11.6 0.7 0.82 9.5 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin DUF605 PF04652.11 GAO85166.1 - 0.68 9.2 18.9 0.94 8.8 13.1 1.2 1 0 0 1 1 1 0 Vta1 like F_bP_aldolase PF01116.15 GAO85167.1 - 1e-97 326.7 0.0 1.1e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF221 PF02714.10 GAO85168.1 - 5.7e-100 334.3 20.7 9.2e-100 333.6 14.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAO85168.1 - 6.7e-42 142.7 1.1 6.7e-42 142.7 0.7 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAO85168.1 - 3.3e-16 59.5 1.0 6.7e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF1192 PF06698.6 GAO85168.1 - 0.041 13.6 0.4 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3445 PF11927.3 GAO85169.1 - 1.8e-84 283.0 0.0 2.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.14 GAO85170.1 - 4.1e-53 179.7 0.1 5.2e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 GAO85170.1 - 5.9e-14 52.4 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 GAO85171.1 - 3e-31 107.3 17.8 3e-31 107.3 12.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) ASFV_J13L PF05568.6 GAO85172.1 - 0.21 11.1 2.6 0.36 10.3 1.8 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein HMG_box PF00505.14 GAO85173.1 - 2.5e-25 88.5 0.4 2.5e-25 88.5 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAO85173.1 - 4.8e-20 71.6 0.8 7.9e-20 71.0 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 GAO85173.1 - 0.0046 17.1 1.8 0.013 15.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) HMG_box_5 PF14887.1 GAO85173.1 - 0.0097 15.6 1.2 0.0097 15.6 0.8 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CENP-H PF05837.7 GAO85174.1 - 9.7e-38 128.5 9.2 9.7e-38 128.5 6.4 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) SpecificRecomb PF10136.4 GAO85174.1 - 0.026 12.5 1.4 0.028 12.4 0.9 1.2 1 0 0 1 1 1 0 Site-specific recombinase ATG11 PF10377.4 GAO85175.1 - 1.1e-40 138.5 4.1 2e-40 137.6 0.0 3.5 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 GAO85175.1 - 9.8e-06 24.6 0.6 9.8e-06 24.6 0.4 5.2 3 2 2 6 6 6 2 Autophagy protein Apg17 DUF3584 PF12128.3 GAO85175.1 - 0.00014 19.3 20.8 0.00014 19.3 14.4 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3584) Nup54 PF13874.1 GAO85175.1 - 0.0019 17.8 4.7 0.0019 17.8 3.3 6.8 6 2 0 7 7 7 1 Nucleoporin complex subunit 54 Borrelia_P83 PF05262.6 GAO85177.1 - 3.8 5.6 28.8 6.3 4.9 19.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_3 PF07859.8 GAO85178.1 - 2.3e-40 138.4 0.0 3.5e-39 134.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO85178.1 - 7.5e-07 28.1 0.0 3.7e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAO85178.1 - 0.0024 17.6 0.0 0.0085 15.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family CsbD PF05532.7 GAO85179.1 - 4.5e-06 26.2 26.5 0.03 14.0 9.2 3.8 1 1 1 2 2 2 2 CsbD-like DUF883 PF05957.8 GAO85179.1 - 0.0035 17.7 4.4 0.011 16.0 1.3 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 GAO85179.1 - 0.013 15.0 0.9 0.016 14.6 0.6 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 GAO85179.1 - 0.016 12.7 0.3 0.018 12.6 0.2 1.0 1 0 0 1 1 1 0 Prominin YtxH PF12732.2 GAO85179.1 - 0.029 14.7 12.4 0.098 13.0 2.3 2.2 1 1 1 2 2 2 0 YtxH-like protein DivIVA PF05103.8 GAO85179.1 - 0.2 11.7 4.6 0.37 10.8 3.2 1.5 1 1 0 1 1 1 0 DivIVA protein ATP-synt_B PF00430.13 GAO85179.1 - 0.74 9.6 6.3 1 9.1 4.0 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Phasin PF05597.6 GAO85179.1 - 0.96 9.2 8.5 1.1 8.9 3.8 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ISG65-75 PF11727.3 GAO85179.1 - 3.4 6.6 13.0 6.6 5.7 9.0 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein FHA PF00498.21 GAO85180.1 - 6.5e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.26 GAO85181.1 - 6.6e-09 35.3 0.3 1.3e-08 34.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Mac PF12464.3 GAO85184.1 - 2.1e-17 62.8 0.1 3.3e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 GAO85184.1 - 5.1e-15 54.7 10.1 1.6e-11 43.5 0.7 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 GAO85184.1 - 7.6e-12 44.1 16.7 1.6e-11 43.1 1.1 3.6 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NB-ARC PF00931.17 GAO85186.1 - 1.5e-08 33.8 0.0 2.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.2 GAO85186.1 - 2.2e-05 24.4 0.0 6.3e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 GAO85186.1 - 5.4e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAO85186.1 - 0.00062 19.9 0.0 0.0024 18.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF676 PF05057.9 GAO85186.1 - 0.0011 18.3 0.0 0.0028 16.9 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAO85186.1 - 0.002 17.7 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Zeta_toxin PF06414.7 GAO85186.1 - 0.0021 17.1 0.0 0.0049 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 GAO85186.1 - 0.0041 17.1 0.9 0.016 15.2 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain KaiC PF06745.8 GAO85186.1 - 0.0042 16.2 0.0 0.011 14.8 0.0 1.6 2 0 0 2 2 2 1 KaiC Cutinase PF01083.17 GAO85186.1 - 0.036 13.8 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase RuvB_N PF05496.7 GAO85186.1 - 0.043 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Abhydrolase_5 PF12695.2 GAO85186.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family IstB_IS21 PF01695.12 GAO85186.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 GAO85186.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAO85186.1 - 0.2 11.0 0.0 0.6 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Alpha-2-MRAP_C PF06401.6 GAO85186.1 - 0.47 10.2 3.2 0.43 10.4 0.8 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain AA_permease_2 PF13520.1 GAO85187.1 - 4.8e-56 190.1 44.3 5.9e-56 189.8 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO85187.1 - 5.3e-12 44.8 37.2 8e-12 44.2 25.8 1.2 1 0 0 1 1 1 1 Amino acid permease ECH PF00378.15 GAO85188.1 - 6.5e-48 162.9 0.1 9.8e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PPR_3 PF13812.1 GAO85188.1 - 0.1 12.9 2.1 34 5.0 0.0 4.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Fmp27_WPPW PF10359.4 GAO85189.1 - 0.024 13.0 0.2 0.049 12.0 0.2 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF327 PF03885.8 GAO85189.1 - 0.59 9.9 4.6 0.89 9.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF327) GatB_N PF02934.10 GAO85191.1 - 2.8e-101 338.2 0.0 3.9e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 GAO85191.1 - 1e-25 90.2 0.1 1.9e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 GatB domain Vitellogenin_N PF01347.17 GAO85191.1 - 0.02 13.1 0.0 0.034 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein amino terminal region Arginase PF00491.16 GAO85192.1 - 4e-78 262.5 0.2 4.6e-78 262.3 0.2 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 GAO85193.1 - 0.00036 20.3 16.3 0.00053 19.8 11.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain NIF PF03031.13 GAO85194.1 - 1.1e-25 90.1 0.0 2.2e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 GAO85194.1 - 6.5e-11 41.9 0.1 1.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAO85194.1 - 1.1e-08 35.0 0.0 3.2e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 GAO85194.1 - 0.029 14.0 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme Asp PF00026.18 GAO85195.1 - 2.3e-106 355.6 0.0 2.8e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO85195.1 - 2.4e-10 40.6 0.1 5.9e-10 39.3 0.0 1.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAO85195.1 - 6.7e-06 26.5 0.3 0.015 15.7 0.0 3.2 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 GAO85195.1 - 0.00032 20.2 0.0 0.0024 17.4 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal AAA PF00004.24 GAO85196.1 - 1.9e-46 157.5 0.1 7.2e-46 155.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAO85196.1 - 3.3e-09 36.6 0.6 1.1e-08 34.9 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAO85196.1 - 4.3e-09 36.5 0.0 8.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAO85196.1 - 1.7e-07 31.4 0.0 6.1e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO85196.1 - 7.3e-07 29.3 0.7 0.00011 22.3 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAO85196.1 - 1.4e-05 24.9 0.0 6.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAO85196.1 - 5.5e-05 22.2 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAO85196.1 - 0.00022 22.0 0.0 0.0012 19.6 0.0 2.2 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 GAO85196.1 - 0.00049 19.2 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 GAO85196.1 - 0.00063 18.9 0.1 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 GAO85196.1 - 0.00067 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 1 1 NTPase NACHT PF05729.7 GAO85196.1 - 0.0008 19.0 1.2 0.056 13.0 0.0 3.0 3 1 0 3 3 3 1 NACHT domain AAA_33 PF13671.1 GAO85196.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAO85196.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 GAO85196.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAO85196.1 - 0.0024 17.8 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO85196.1 - 0.0025 16.6 0.0 0.0045 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 GAO85196.1 - 0.0032 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 GAO85196.1 - 0.0039 16.7 0.3 0.014 14.9 0.0 2.0 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 GAO85196.1 - 0.0045 16.6 0.0 0.034 13.7 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 GAO85196.1 - 0.0053 16.2 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 GAO85196.1 - 0.006 16.9 0.1 0.48 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAO85196.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAO85196.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAO85196.1 - 0.012 15.0 0.5 0.031 13.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 GAO85196.1 - 0.012 15.2 1.0 0.15 11.7 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 GAO85196.1 - 0.016 14.6 2.6 0.064 12.6 0.1 2.5 2 1 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 GAO85196.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 GAO85196.1 - 0.03 14.6 0.0 0.089 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO85196.1 - 0.034 13.7 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 GAO85196.1 - 0.043 12.9 1.2 0.48 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Cast PF10174.4 GAO85196.1 - 0.059 11.4 1.3 0.1 10.6 0.5 1.6 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Sigma54_activ_2 PF14532.1 GAO85196.1 - 0.078 13.0 0.0 0.4 10.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAO85196.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 GAO85196.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_Hsp90 PF03225.9 GAO85196.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 GAO85196.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.16 GAO85197.1 - 4e-22 77.8 0.1 3.3e-21 74.9 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 GAO85198.1 - 1.4e-29 102.1 0.0 3.3e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 GAO85199.1 - 1.1e-54 184.1 2.1 2.6e-54 182.9 1.5 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 GAO85199.1 - 4.4e-14 52.6 0.0 1.3e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 GAO85199.1 - 0.025 14.3 0.2 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Cortex-I_coil PF09304.5 GAO85199.1 - 0.18 11.8 3.3 0.28 11.2 1.3 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil NTP_transf_5 PF14907.1 GAO85199.1 - 1.4 8.1 5.1 11 5.2 0.2 3.1 2 1 1 3 3 3 0 Uncharacterised nucleotidyltransferase ArsA_ATPase PF02374.10 GAO85200.1 - 1.4e-115 385.5 0.0 1.6e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 GAO85200.1 - 3.5e-17 62.4 0.2 5.8e-17 61.7 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAO85200.1 - 1.1e-08 35.1 0.0 8.2e-08 32.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAO85200.1 - 1.5e-06 27.6 0.0 3.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAO85200.1 - 3.6e-05 23.2 1.3 0.00066 19.1 0.0 2.7 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAO85200.1 - 0.01 15.2 0.3 0.034 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 GAO85200.1 - 0.011 14.9 0.1 0.03 13.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 GAO85200.1 - 0.012 15.3 0.1 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain MipZ PF09140.6 GAO85200.1 - 0.013 14.5 0.1 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 GAO85200.1 - 0.025 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 GAO85200.1 - 0.025 13.9 0.0 0.065 12.5 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 GAO85200.1 - 0.035 12.9 0.1 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 GAO85200.1 - 0.11 11.3 0.2 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 GAO85200.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.6 GAO85200.1 - 0.15 11.0 0.1 0.81 8.7 0.0 1.9 2 0 0 2 2 2 0 VirC1 protein A1_Propeptide PF07966.7 GAO85200.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.5 3 0 0 3 3 3 0 A1 Propeptide Transthyretin PF00576.16 GAO85201.1 - 3.7e-23 81.5 0.0 1.7e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 HIUase/Transthyretin family DUF4198 PF10670.4 GAO85201.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Big_1 PF02369.11 GAO85201.1 - 0.21 11.5 4.7 0.34 10.8 3.2 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Aft1_HRA PF11786.3 GAO85202.1 - 5e-29 100.3 10.2 5e-29 100.3 7.1 2.8 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 GAO85202.1 - 1.8e-25 89.7 0.9 1.8e-25 89.7 0.7 3.5 4 1 0 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 GAO85202.1 - 1e-21 77.1 8.2 1e-21 77.1 5.7 2.9 2 1 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 GAO85202.1 - 4.6e-13 48.9 4.7 7.5e-13 48.2 3.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO85202.1 - 6.3e-06 25.9 5.4 1.2e-05 25.0 3.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAO85202.1 - 0.011 16.0 5.1 0.022 15.0 3.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.4 GAO85202.1 - 0.31 9.2 17.2 0.42 8.8 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Spc97_Spc98 PF04130.8 GAO85203.1 - 7.3e-117 390.9 0.0 1e-116 390.4 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2373 PF10180.4 GAO85204.1 - 2e-22 78.5 1.1 4.1e-22 77.4 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 GAO85205.1 - 1.3e-50 171.3 0.1 1.7e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAO85205.1 - 5.5e-13 47.9 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Glyco_hydro_18 PF00704.23 GAO85207.1 - 3.2e-96 322.7 3.3 3.7e-96 322.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 GAO85208.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 GAO85208.1 - 4.9e-28 96.6 1.7 1e-27 95.6 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 GAO85208.1 - 5.9e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAO85208.1 - 8.8e-06 25.8 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAO85208.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAO85208.1 - 0.0011 18.8 0.5 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAO85208.1 - 0.0041 17.2 0.5 0.0057 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 GAO85208.1 - 0.013 15.3 0.4 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 GAO85208.1 - 0.065 13.2 0.6 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 GAO85208.1 - 0.12 10.6 1.9 4.4 5.5 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF971 PF06155.7 GAO85208.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) zf-H2C2_2 PF13465.1 GAO85209.1 - 5.2e-11 42.2 7.4 6e-05 23.1 0.1 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAO85209.1 - 2.4e-06 27.5 20.4 0.0058 16.9 4.6 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type Bunya_G2 PF03563.8 GAO85209.1 - 0.047 12.5 3.3 0.077 11.8 2.3 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 GAO85209.1 - 0.97 9.4 8.0 1.9 8.5 0.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 GAO85209.1 - 2.4 8.6 26.0 1.3 9.4 2.9 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Ribonuclease_T2 PF00445.13 GAO85210.1 - 3.7e-47 160.3 0.1 7.6e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 GAO85210.1 - 0.038 13.5 0.1 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) DUF155 PF02582.9 GAO85211.1 - 2.4e-44 151.3 0.0 3.2e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 GAO85212.1 - 3.7e-20 71.9 1.4 1e-17 64.0 0.1 3.6 3 1 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 GAO85212.1 - 5e-05 23.0 1.0 0.01 15.7 0.5 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat Vps39_1 PF10366.4 GAO85212.1 - 0.022 14.7 0.1 0.085 12.8 0.0 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Vps8 PF12816.2 GAO85212.1 - 0.13 11.4 0.2 33 3.6 0.0 3.2 3 0 0 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 Vps39_2 PF10367.4 GAO85212.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_19 PF14559.1 GAO85212.1 - 0.49 10.7 2.9 8.2 6.8 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85212.1 - 1.3 9.1 6.4 2.3 8.3 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.6 GAO85213.1 - 8.1 4.1 11.6 8.4 4.1 8.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Metallopep PF12044.3 GAO85214.1 - 9.2e-174 577.8 0.0 1.3e-173 577.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family CP2 PF04516.10 GAO85214.1 - 3.9e-94 314.1 0.0 6.3e-94 313.4 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Reprolysin_5 PF13688.1 GAO85214.1 - 0.0039 17.1 0.3 0.008 16.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Jacalin PF01419.12 GAO85214.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Jacalin-like lectin domain DUF3534 PF12053.3 GAO85214.1 - 1.6 8.6 7.4 5 6.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) Whi5 PF08528.6 GAO85215.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Whi5 like DNA_ligase_A_M PF01068.16 GAO85216.1 - 6e-53 179.2 0.5 3.9e-50 170.0 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAO85216.1 - 2.6e-43 147.8 0.0 5.5e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAO85216.1 - 1.4e-19 70.2 0.0 7.4e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region TerB PF05099.8 GAO85216.1 - 0.99 9.1 5.6 9.6 5.9 0.1 2.9 3 0 0 3 3 3 0 Tellurite resistance protein TerB RINT1_TIP1 PF04437.8 GAO85217.1 - 5.1e-193 642.1 0.1 6.1e-192 638.5 0.0 2.2 2 0 0 2 2 2 1 RINT-1 / TIP-1 family TPR_11 PF13414.1 GAO85217.1 - 0.034 13.7 1.2 0.081 12.5 0.8 1.6 1 0 0 1 1 1 0 TPR repeat DivIVA PF05103.8 GAO85217.1 - 0.047 13.7 8.2 0.15 12.1 5.7 1.9 1 0 0 1 1 1 0 DivIVA protein Pyridoxal_deC PF00282.14 GAO85218.1 - 5.2e-79 265.3 0.0 1.1e-77 260.9 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAO85218.1 - 4.6e-06 25.6 0.0 6.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO85218.1 - 2.9e-05 23.3 0.0 5.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PUF PF00806.14 GAO85219.1 - 2.5e-14 51.8 0.0 0.093 12.2 0.0 6.8 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RCC1 PF00415.13 GAO85220.1 - 4e-31 106.9 0.3 2.1e-08 34.2 0.0 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAO85220.1 - 4.4e-16 58.0 16.0 3.5e-11 42.4 0.0 6.2 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 GAO85221.1 - 9.9e-31 106.5 0.6 2.1e-30 105.4 0.4 1.5 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.10 GAO85221.1 - 0.0015 17.3 3.6 0.064 12.0 0.0 3.2 4 0 0 4 4 4 2 Exo70 exocyst complex subunit Apc5 PF12862.2 GAO85221.1 - 0.068 13.0 0.2 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 IncA PF04156.9 GAO85221.1 - 0.074 12.6 7.4 0.029 13.9 3.0 1.9 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 GAO85222.1 - 2.1e-61 207.3 0.0 2.9e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85222.1 - 2.9e-42 144.5 0.0 4.2e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85222.1 - 9e-09 34.6 0.0 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAO85222.1 - 0.0035 16.4 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPP_enzyme_N PF02776.13 GAO85223.1 - 8.6e-34 116.4 0.0 1.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO85223.1 - 6.1e-24 84.3 0.1 2.4e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAO85223.1 - 1.3e-15 57.2 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 GAO85223.1 - 0.035 12.8 0.1 0.098 11.3 0.1 1.6 2 0 0 2 2 2 0 Dehydrogenase E1 component OCC1 PF15506.1 GAO85223.1 - 0.69 9.8 3.7 3.9 7.4 0.2 3.0 3 0 0 3 3 3 0 OCC1 family THUMP PF02926.12 GAO85224.1 - 1.1e-13 51.2 0.0 2.7e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 THUMP domain Lgl_C PF08596.5 GAO85225.1 - 2.4e-142 474.0 0.0 6.3e-142 472.6 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 GAO85225.1 - 3.9e-05 23.3 3.6 0.46 10.4 0.0 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Nup160 PF11715.3 GAO85225.1 - 0.025 12.7 0.0 0.12 10.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ASF1_hist_chap PF04729.8 GAO85226.1 - 7.8e-68 226.9 0.0 1e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 GAO85226.1 - 1 7.1 28.6 1.4 6.7 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 GAO85227.1 - 5e-97 324.9 4.2 6.4e-94 314.8 0.0 3.8 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 GAO85227.1 - 3.1e-05 24.5 0.1 0.00046 20.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85227.1 - 0.00022 21.5 0.1 0.071 13.7 0.0 4.3 2 2 1 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 GAO85227.1 - 0.00069 19.3 0.3 0.00069 19.3 0.2 2.6 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat Piwi PF02171.12 GAO85228.1 - 2.7e-68 230.1 0.0 4.2e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 GAO85228.1 - 3.2e-19 68.0 0.0 9.6e-19 66.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 GAO85228.1 - 7.7e-19 67.3 0.1 1.4e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 PAZ domain Bromodomain PF00439.20 GAO85229.1 - 1.2e-20 73.1 3.3 2.5e-19 68.9 0.2 3.4 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 GAO85229.1 - 3.1e-10 39.6 0.0 1.9e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated SPARC_Ca_bdg PF10591.4 GAO85229.1 - 0.097 12.7 3.8 0.36 10.8 0.5 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region HisKA_3 PF07730.8 GAO85229.1 - 0.12 12.7 3.8 0.62 10.4 0.0 3.4 3 0 0 3 3 3 0 Histidine kinase VanZ PF04892.7 GAO85230.1 - 6.1e-10 39.1 1.0 1.2e-09 38.2 0.7 1.4 1 1 0 1 1 1 1 VanZ like family FtsX PF02687.16 GAO85230.1 - 0.21 11.3 4.1 9.9 5.9 1.1 2.3 2 1 0 2 2 2 0 FtsX-like permease family P5-ATPase PF12409.3 GAO85230.1 - 0.41 10.5 2.1 0.71 9.7 1.2 1.6 1 1 1 2 2 2 0 P5-type ATPase cation transporter TrkH PF02386.11 GAO85230.1 - 0.49 8.9 2.0 3.5 6.1 0.1 2.4 2 1 1 3 3 3 0 Cation transport protein Y_phosphatase PF00102.22 GAO85231.1 - 8e-53 179.1 0.0 1.5e-52 178.3 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAO85231.1 - 8.3e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAO85231.1 - 0.0017 18.4 0.0 0.0084 16.1 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 GAO85231.1 - 0.058 12.9 0.8 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Mid2 PF04478.7 GAO85232.1 - 2.4e-06 27.0 4.3 2.4e-06 27.0 3.0 2.7 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor DUF2029 PF09594.5 GAO85232.1 - 0.065 12.7 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF1510 PF07423.6 GAO85232.1 - 0.27 10.5 12.9 0.51 9.6 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PAP1 PF08601.5 GAO85232.1 - 0.44 10.1 23.2 0.6 9.7 16.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Tim54 PF11711.3 GAO85232.1 - 1 7.8 4.5 1.7 7.1 3.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ndc1_Nup PF09531.5 GAO85232.1 - 1.1 7.5 7.3 1.4 7.2 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.4 GAO85232.1 - 1.2 7.7 5.8 1.6 7.3 4.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Herpes_UL32 PF06070.6 GAO85232.1 - 1.8 6.9 20.6 1.9 6.8 14.3 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF566 PF04484.7 GAO85232.1 - 5.4 6.4 20.2 7.7 5.9 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DHHW PF14286.1 GAO85232.1 - 6.7 5.9 10.1 8.2 5.6 7.0 1.2 1 0 0 1 1 1 0 DHHW protein Pex19 PF04614.7 GAO85235.1 - 3.5e-69 233.1 9.4 3.5e-69 233.1 6.5 2.3 2 1 0 2 2 2 1 Pex19 protein family Transposase_22 PF02994.9 GAO85235.1 - 0.0055 15.2 0.0 0.011 14.3 0.0 1.4 1 0 0 1 1 1 1 L1 transposable element Pup PF05639.6 GAO85235.1 - 0.015 15.8 0.7 0.067 13.6 0.5 2.2 1 0 0 1 1 1 0 Pup-like protein DUF1631 PF07793.6 GAO85235.1 - 0.065 11.3 6.5 0.29 9.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1631) DUF3835 PF12927.2 GAO85235.1 - 0.32 11.9 5.9 1.4 9.9 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3835) B12-binding_2 PF02607.12 GAO85235.1 - 0.87 9.6 3.5 0.79 9.7 0.6 2.4 2 1 0 2 2 2 0 B12 binding domain FliE PF02049.13 GAO85235.1 - 1.3 9.1 4.6 2.9 7.9 0.0 2.9 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE bZIP_1 PF00170.16 GAO85236.1 - 9.1e-05 22.3 9.6 9.1e-05 22.3 6.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAO85236.1 - 0.017 14.9 10.5 0.017 14.9 7.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 GAO85236.1 - 0.1 11.5 3.6 0.48 9.3 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 GAO85236.1 - 0.13 12.3 1.6 0.22 11.6 1.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 GAO85236.1 - 0.13 11.9 5.1 7.3 6.3 2.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_2 PF12848.2 GAO85236.1 - 0.18 11.6 6.1 3.8 7.4 4.1 2.2 2 0 0 2 2 2 0 ABC transporter CENP-Q PF13094.1 GAO85236.1 - 6 6.8 10.6 0.6 10.1 4.1 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Stm1_N PF09598.5 GAO85237.1 - 7.9e-19 68.1 7.5 7.9e-19 68.1 5.2 4.8 3 1 0 3 3 3 1 Stm1 DUF1793 PF08760.6 GAO85238.1 - 1.1e-74 249.9 1.1 2.3e-74 248.9 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DEAD PF00270.24 GAO85240.1 - 6.2e-40 136.4 0.0 1.2e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO85240.1 - 1e-26 92.6 0.1 1.9e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO85240.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HCO3_cotransp PF00955.16 GAO85241.1 - 1.6e-68 231.6 11.6 2.7e-42 145.1 2.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC PF00098.18 GAO85242.1 - 1.3e-11 43.8 9.7 1.7e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 GAO85242.1 - 7.3e-07 28.8 5.2 0.00064 19.3 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 GAO85242.1 - 0.00044 19.8 0.1 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 GAO85242.1 - 0.0011 18.6 6.0 0.28 10.9 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 GAO85242.1 - 0.0067 16.0 9.3 0.39 10.4 0.4 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 GAO85242.1 - 0.058 12.9 0.1 0.058 12.9 0.1 3.5 2 1 1 3 3 3 0 Zinc knuckle eIF3g PF12353.3 GAO85242.1 - 2.5 8.0 7.7 4.7 7.1 1.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G GST_N_3 PF13417.1 GAO85243.1 - 3.4e-14 52.8 0.0 6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO85243.1 - 2.3e-12 46.8 0.0 5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO85243.1 - 4.8e-12 45.6 0.0 8.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO85243.1 - 6.7e-12 45.2 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO85243.1 - 1.6e-11 43.8 0.2 3.5e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO85243.1 - 3.7e-10 40.1 0.1 7.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAO85243.1 - 0.068 13.5 0.0 1.1 9.6 0.0 2.5 1 1 0 1 1 1 0 MetRS-N binding domain NAD_binding_6 PF08030.7 GAO85244.1 - 7.2e-20 71.4 0.0 1.4e-17 64.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAO85244.1 - 9.4e-17 61.2 7.8 9.4e-17 61.2 5.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAO85244.1 - 1.6e-16 60.0 0.0 4.9e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain DUF2970 PF11174.3 GAO85244.1 - 3.7 7.2 7.9 2.4 7.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CLU PF13236.1 GAO85246.1 - 1.1e-80 270.1 0.0 2.3e-80 269.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAO85246.1 - 1.1e-56 191.4 0.1 5.7e-56 189.0 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 GAO85246.1 - 8.6e-29 99.3 13.0 3.8e-10 39.5 0.0 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.1 GAO85246.1 - 1.2e-26 92.6 0.2 3.3e-26 91.2 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 GAO85246.1 - 5.8e-16 57.8 0.0 0.00014 21.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAO85246.1 - 2.1e-05 24.0 1.0 0.44 10.2 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAO85246.1 - 4.1e-05 23.1 0.4 0.36 10.8 0.1 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO85246.1 - 0.025 14.3 2.0 1.1 9.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO85246.1 - 0.026 15.2 0.0 5.8 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat EnY2 PF10163.4 GAO85246.1 - 0.055 13.4 3.0 0.18 11.7 0.2 3.1 3 0 0 3 3 3 0 Transcription factor e(y)2 AAA_16 PF13191.1 GAO85247.1 - 1.1e-05 25.4 1.6 0.00087 19.3 1.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 GAO85247.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase ATP-synt_ab PF00006.20 GAO85247.1 - 0.0054 16.2 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 GAO85247.1 - 0.017 15.5 0.1 0.18 12.3 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 GAO85247.1 - 0.031 13.6 0.1 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Lipase_chap PF03280.9 GAO85247.1 - 0.033 13.7 0.1 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein AAA_22 PF13401.1 GAO85247.1 - 0.05 13.7 0.2 0.15 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 GAO85247.1 - 0.058 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 KaiC RTA1 PF04479.8 GAO85249.1 - 1.6e-52 178.2 12.0 2.3e-52 177.7 8.3 1.2 1 0 0 1 1 1 1 RTA1 like protein ASC PF00858.19 GAO85249.1 - 1.1 7.7 3.4 1.7 7.2 2.4 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel XFP_N PF09364.5 GAO85250.1 - 2e-154 513.7 0.0 2.6e-154 513.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 GAO85250.1 - 1.4e-68 230.2 0.0 2.5e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 GAO85250.1 - 3.6e-67 225.4 0.0 5.4e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 GAO85250.1 - 0.0039 16.7 0.1 0.0084 15.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 GAO85251.1 - 4e-93 312.0 0.0 4.8e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 GAO85251.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Ras PF00071.17 GAO85252.1 - 2.6e-57 192.7 0.0 3.1e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO85252.1 - 1.4e-20 73.9 0.0 2.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO85252.1 - 1.8e-14 53.3 0.0 4.5e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO85252.1 - 3e-07 30.0 0.0 7.1e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAO85252.1 - 4.6e-07 29.2 0.0 7.1e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAO85252.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAO85252.1 - 0.0053 16.7 0.1 0.0097 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO85252.1 - 0.065 13.3 0.0 0.25 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain Ribosomal_S7e PF01251.13 GAO85253.1 - 4e-85 284.0 0.4 4.5e-85 283.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 GAO85254.1 - 2.2e-218 725.9 0.0 6.1e-218 724.4 0.0 1.6 2 0 0 2 2 2 1 Dynactin p62 family Methyltransf_11 PF08241.7 GAO85255.1 - 6.3e-11 42.6 0.0 1.4e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO85255.1 - 2.6e-07 31.0 0.0 4.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO85255.1 - 6.5e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85255.1 - 4.3e-05 23.1 0.0 8.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO85255.1 - 0.0038 17.5 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO85255.1 - 0.0099 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.9 GAO85256.1 - 5.5e-61 205.0 0.0 6.3e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PAS_4 PF08448.5 GAO85256.1 - 0.044 13.8 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold E1-E2_ATPase PF00122.15 GAO85257.1 - 3.6e-58 196.3 0.2 3.6e-58 196.3 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO85257.1 - 3.5e-47 160.2 6.9 3.5e-47 160.2 4.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO85257.1 - 5.1e-27 95.6 0.0 2.4e-26 93.4 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO85257.1 - 1.2e-18 66.8 0.0 2.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO85257.1 - 3.8e-15 56.5 0.0 8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO85257.1 - 4.4e-08 32.4 0.8 1.9e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAO85257.1 - 5.5e-05 22.8 0.1 0.0012 18.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 GAO85257.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) DUF1774 PF08611.5 GAO85257.1 - 5.7 7.1 9.0 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) K_oxygenase PF13434.1 GAO85258.1 - 2.6e-15 56.2 0.0 3.4e-09 36.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAO85258.1 - 7.4e-14 52.2 0.0 3.7e-07 30.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO85258.1 - 2.5e-05 24.0 0.1 0.22 11.2 0.4 3.5 4 1 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO85258.1 - 9.3e-05 22.3 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO85258.1 - 0.00015 20.8 0.7 0.00024 20.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 GAO85258.1 - 0.0013 18.8 0.0 0.096 12.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAO85258.1 - 0.01 14.8 0.8 0.02 13.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 GAO85258.1 - 0.011 14.6 0.0 0.058 12.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAO85258.1 - 0.024 13.7 0.1 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 GAO85258.1 - 0.031 14.2 0.1 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO85258.1 - 0.034 12.6 0.0 0.068 11.6 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 GAO85258.1 - 0.034 14.5 0.5 44 4.5 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO85258.1 - 0.12 11.9 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 GAO85258.1 - 0.17 10.6 0.2 13 4.4 0.0 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A HMG_CoA_synt_C PF08540.5 GAO85260.1 - 5.1e-104 347.7 0.2 6.4e-104 347.3 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 GAO85260.1 - 8.6e-95 315.2 0.1 1.5e-94 314.3 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.10 GAO85261.1 - 2.6e-34 117.5 1.2 7.9e-20 70.6 0.0 2.9 4 0 0 4 4 4 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAO85261.1 - 4.3e-13 49.3 0.0 1.1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAO85261.1 - 5.7e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAO85261.1 - 0.00085 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1765 PF08578.5 GAO85262.1 - 9.4e-44 148.4 10.5 1.9e-43 147.5 6.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 GAO85263.1 - 2.7e-25 87.8 1.7 3.8e-25 87.3 1.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 GAO85263.1 - 8.4e-06 25.6 0.1 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 GAO85264.1 - 3.1e-39 132.6 0.2 1.7e-19 69.3 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAO85264.1 - 1.8e-09 36.7 1.2 1.8e-09 36.7 0.9 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_23 PF13384.1 GAO85264.1 - 0.079 12.6 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain zf-ribbon_3 PF13248.1 GAO85264.1 - 0.48 9.7 5.0 0.092 11.9 0.7 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF3210 PF11489.3 GAO85265.1 - 1.5e-289 962.7 66.4 1.5e-289 962.7 46.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 GAO85266.1 - 7.2e-42 141.9 14.2 8.6e-42 141.6 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.5 GAO85266.1 - 0.0011 18.7 14.1 0.0015 18.2 9.8 1.2 1 0 0 1 1 1 1 COPI associated protein DUF1469 PF07332.6 GAO85266.1 - 3.4 7.4 18.4 0.066 12.9 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PEMT PF04191.8 GAO85266.1 - 4.7 7.3 12.3 5.6 7.1 1.7 2.2 1 1 1 2 2 2 0 Phospholipid methyltransferase TPR_19 PF14559.1 GAO85267.1 - 3.8e-13 49.5 0.7 2.6e-08 34.1 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAO85267.1 - 2.6e-09 37.5 0.1 0.004 17.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85267.1 - 4.2e-05 23.3 2.5 0.0015 18.4 0.6 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85267.1 - 6.2e-05 22.6 0.9 1.9 8.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 GAO85267.1 - 0.00018 21.4 3.6 0.045 13.6 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85267.1 - 0.00052 20.4 3.8 20 6.1 0.1 4.5 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO85267.1 - 0.00054 20.2 0.9 2.7 8.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAO85267.1 - 0.004 16.7 4.2 0.023 14.3 0.6 3.3 3 2 1 4 4 4 2 TPR repeat TPR_10 PF13374.1 GAO85267.1 - 0.01 15.7 0.4 0.25 11.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO85267.1 - 0.07 13.5 0.4 14 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAO85267.1 - 0.081 12.5 0.4 23 4.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAO85267.1 - 0.083 13.1 1.3 0.6 10.4 0.2 3.1 4 0 0 4 4 1 0 Tetratricopeptide repeat SLT_L PF14718.1 GAO85267.1 - 0.28 11.0 3.6 2.3 8.0 0.1 3.1 3 1 1 4 4 4 0 Soluble lytic murein transglycosylase L domain TPR_8 PF13181.1 GAO85267.1 - 0.66 9.9 4.2 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 GAO85268.1 - 2.8e-05 23.7 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAO85268.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cellulase-like PF12876.2 GAO85268.1 - 0.12 12.7 0.2 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Sugar-binding cellulase-like adh_short PF00106.20 GAO85269.1 - 1.8e-32 112.5 4.2 2.4e-32 112.1 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO85269.1 - 3.5e-25 89.1 0.2 8.9e-25 87.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO85269.1 - 2.3e-16 59.9 1.6 3.3e-16 59.4 1.1 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 GAO85269.1 - 0.0016 18.3 0.2 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 GAO85269.1 - 0.0095 15.6 1.5 0.015 14.9 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 GAO85269.1 - 0.035 14.1 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 GAO85269.1 - 0.097 12.0 0.3 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 GAO85270.1 - 2.4e-58 197.3 0.0 3.2e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85270.1 - 2.2e-31 108.8 0.0 2.8e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85270.1 - 0.0024 16.9 0.0 0.011 14.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 GAO85270.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO85270.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAO85270.1 - 0.016 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 GAO85271.1 - 4.9e-52 176.6 0.0 7.5e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85271.1 - 8.2e-24 84.0 0.0 2.1e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAO85271.1 - 0.021 13.6 0.1 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 GAO85272.1 - 3.4e-27 94.6 20.7 3.8e-27 94.5 14.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Cyt-b5 PF00173.23 GAO85274.1 - 1.2e-15 57.1 0.0 2.1e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 GAO85275.1 - 1.2e-86 284.2 19.5 5.9e-14 51.8 0.0 7.7 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 GAO85275.1 - 3.5e-13 48.6 0.0 0.3 10.6 0.0 7.7 7 1 0 7 7 7 3 SAP domain HeH PF12949.2 GAO85275.1 - 6.7e-12 44.7 0.8 0.01 15.3 0.1 6.1 6 0 0 6 6 6 3 HeH/LEM domain APC2 PF08672.6 GAO85275.1 - 1.6e-07 31.4 1.3 12 6.2 0.0 7.1 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 GAO85275.1 - 0.0005 19.7 4.8 15 5.4 0.0 5.7 6 0 0 6 6 6 0 Slx4 endonuclease LEM PF03020.10 GAO85275.1 - 0.00057 19.2 0.0 28 4.2 0.0 5.1 5 0 0 5 5 5 0 LEM domain Amidase02_C PF12123.3 GAO85275.1 - 0.0011 18.5 0.9 0.57 9.8 0.2 4.2 5 0 0 5 5 5 1 N-acetylmuramoyl-l-alanine amidase SAM_2 PF07647.12 GAO85275.1 - 0.073 12.9 5.6 61 3.5 0.1 5.6 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) SAP30_Sin3_bdg PF13867.1 GAO85275.1 - 1.5 8.7 3.8 49 3.8 0.1 4.0 4 0 0 4 4 4 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2795 PF11387.3 GAO85275.1 - 3.6 7.5 8.2 42 4.1 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) DUF1470 PF07336.6 GAO85275.1 - 5.5 7.3 21.4 1.6 9.0 1.5 5.4 3 1 3 6 6 6 0 Protein of unknown function (DUF1470) PQ-loop PF04193.9 GAO85276.1 - 3e-19 68.3 22.5 7.1e-11 41.4 1.6 3.0 3 1 1 4 4 4 2 PQ loop repeat TMEM107 PF14995.1 GAO85276.1 - 0.029 14.5 0.8 0.029 14.5 0.5 2.1 2 1 0 2 2 2 0 Transmembrane protein DUF3357 PF11837.3 GAO85276.1 - 0.14 12.0 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) NTF2 PF02136.15 GAO85277.1 - 6.8e-36 123.2 1.3 7.6e-36 123.0 0.9 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 GAO85277.1 - 0.0093 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4518 PF15008.1 GAO85277.1 - 0.11 11.5 0.3 0.14 11.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Mtr2 PF10429.4 GAO85277.1 - 0.11 12.2 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Surp PF01805.15 GAO85278.1 - 1.8e-17 62.7 0.0 3.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Surp module DUF605 PF04652.11 GAO85281.1 - 1.1 8.5 16.4 1.2 8.4 11.4 1.0 1 0 0 1 1 1 0 Vta1 like DUF2201_N PF13203.1 GAO85281.1 - 1.2 8.2 5.7 0.47 9.5 2.3 1.4 1 1 1 2 2 2 0 Putative metallopeptidase domain Glycos_transf_2 PF00535.21 GAO85282.1 - 1.9e-33 115.5 0.0 2.4e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAO85282.1 - 8.6e-14 51.8 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 GAO85282.1 - 3e-08 33.0 0.0 4.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAO85282.1 - 7.5e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 GAO85282.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 GAO85282.1 - 0.032 14.5 0.0 0.08 13.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF1749 PF08538.5 GAO85283.1 - 1e-105 352.9 0.0 1.2e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAO85283.1 - 1.4e-07 31.6 0.5 2.1e-07 31.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85283.1 - 9.9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAO85283.1 - 0.00078 19.0 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.15 GAO85283.1 - 0.012 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAO85283.1 - 0.074 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO85283.1 - 0.12 11.5 0.0 0.36 10.0 0.0 1.7 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 GAO85283.1 - 0.15 11.4 0.0 1.8 7.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) AHS1 PF02682.11 GAO85284.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 WD40 PF00400.27 GAO85284.1 - 0.28 11.1 7.0 31 4.6 0.8 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat SDA1 PF05285.7 GAO85284.1 - 0.86 8.8 23.5 0.027 13.7 11.5 1.8 2 0 0 2 2 2 0 SDA1 Pox_RNA_Pol_19 PF05320.7 GAO85284.1 - 3.7 7.2 9.7 7.8 6.2 6.7 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ebola_NP PF05505.7 GAO85284.1 - 4.7 5.1 8.0 6.7 4.6 5.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein YL1 PF05764.8 GAO85284.1 - 5.5 6.5 16.7 11 5.4 11.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 GAO85284.1 - 7.6 4.8 14.6 11 4.3 10.1 1.1 1 0 0 1 1 1 0 Daxx Family TT_ORF2a PF08197.6 GAO85285.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 pORF2a truncated protein Vps35 PF03635.12 GAO85286.1 - 0 1039.4 0.0 0 1039.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3907 PF13047.1 GAO85286.1 - 0.038 13.6 0.0 5.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) NST1 PF13945.1 GAO85287.1 - 1.1e-73 247.3 2.2 1.1e-73 247.3 1.5 4.9 4 1 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 GAO85288.1 - 1.4e-34 118.8 0.0 1.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO85288.1 - 1.2e-07 32.1 0.0 3.1e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MRP-L28 PF09812.4 GAO85289.1 - 3.7e-08 33.3 0.1 4.5e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FANCL_C PF11793.3 GAO85290.1 - 7.5e-06 25.8 2.2 1.3e-05 25.0 1.5 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 GAO85290.1 - 1.7e-05 24.7 6.4 3e-05 23.9 4.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAO85290.1 - 0.0023 17.7 4.9 0.0039 16.9 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain TPP_enzyme_N PF02776.13 GAO85291.1 - 3.5e-59 199.1 0.0 5.1e-57 192.0 0.0 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAO85291.1 - 4.6e-50 169.1 0.1 1.9e-48 163.8 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO85291.1 - 5e-37 126.7 0.1 1.1e-36 125.5 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 GAO85291.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.4 GAO85292.1 - 1.3e-20 72.4 0.1 2.7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 GAO85292.1 - 3.6e-15 55.7 0.7 1.5e-14 53.8 0.5 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAO85292.1 - 1.5e-12 47.4 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 GAO85292.1 - 0.032 13.7 0.1 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 GAO85292.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix RNase_H2-Ydr279 PF09468.5 GAO85293.1 - 1.2e-106 356.3 0.0 1.5e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) SnAPC_2_like PF11035.3 GAO85293.1 - 0.00015 21.4 1.4 0.00024 20.7 1.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex subunit 2-like PA28_alpha PF02251.13 GAO85293.1 - 0.1 12.7 0.4 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit RAP1 PF07218.6 GAO85293.1 - 0.43 8.6 3.3 3.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Mucin PF01456.12 GAO85293.1 - 1.2 8.9 7.3 0.88 9.3 0.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-primase PF09329.6 GAO85294.1 - 4.8e-19 67.6 0.7 7.9e-19 66.9 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.5 GAO85296.1 - 7.2e-31 105.5 2.1 8.4e-31 105.3 0.8 1.6 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF745 PF05335.8 GAO85296.1 - 0.01 15.4 8.4 0.015 14.8 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) SPX PF03105.14 GAO85296.1 - 0.064 13.0 1.4 0.13 12.0 0.9 1.5 1 1 0 1 1 1 0 SPX domain DUF1682 PF07946.9 GAO85296.1 - 0.16 10.7 5.2 0.26 10.0 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Macoilin PF09726.4 GAO85296.1 - 3.7 5.7 11.8 4.6 5.3 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Tic20 PF09685.5 GAO85297.1 - 2.5e-07 30.6 0.9 3.3e-07 30.2 0.7 1.2 1 0 0 1 1 1 1 Tic20-like protein FCH PF00611.18 GAO85298.1 - 2.2e-20 72.6 0.0 1.9e-19 69.6 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAO85298.1 - 1.7e-13 49.7 0.0 3.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO85298.1 - 1.1e-11 44.1 0.0 2.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO85298.1 - 1.9e-09 36.8 0.0 4.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Not1 PF04054.10 GAO85299.1 - 3.7e-141 470.4 0.3 8.2e-141 469.2 0.0 1.7 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 GAO85299.1 - 1.1e-52 177.6 0.9 3.3e-52 176.0 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Seipin PF06775.9 GAO85300.1 - 4.4e-71 238.5 0.2 5.8e-71 238.1 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 GAO85301.1 - 1.6e-55 188.1 0.0 2.5e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 GAO85301.1 - 3.5e-43 147.2 0.0 5.3e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 GAO85301.1 - 0.00084 18.2 0.0 0.0043 15.8 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 GAO85301.1 - 0.027 14.2 0.0 0.82 9.3 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAO85301.1 - 0.25 10.7 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Pex14_N PF04695.8 GAO85304.1 - 2.5e-39 134.4 0.0 2.5e-39 134.4 0.0 3.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 GAO85304.1 - 0.0015 18.6 0.4 0.0015 18.6 0.3 2.0 2 0 0 2 2 2 1 Zinc finger-containing protein DUF3584 PF12128.3 GAO85304.1 - 0.0055 14.1 5.1 0.0074 13.6 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 GAO85304.1 - 0.01 15.6 1.5 0.075 12.8 0.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3829 PF12889.2 GAO85304.1 - 0.058 12.5 0.8 0.087 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) ERM PF00769.14 GAO85304.1 - 0.075 12.5 7.0 0.07 12.6 3.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Cytochrom_B562 PF07361.6 GAO85304.1 - 0.16 12.4 0.9 0.42 11.0 0.7 1.7 1 0 0 1 1 1 0 Cytochrome b562 DUF848 PF05852.6 GAO85304.1 - 0.79 9.5 4.3 1.8 8.3 2.4 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sipho_Gp157 PF05565.6 GAO85304.1 - 0.9 9.1 4.3 3.3 7.2 0.5 2.7 2 1 0 3 3 3 0 Siphovirus Gp157 Ndc80_HEC PF03801.8 GAO85305.1 - 2.9e-64 215.3 0.0 1.1e-63 213.4 0.0 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family Filament PF00038.16 GAO85305.1 - 0.0024 17.4 46.6 0.0036 16.8 15.3 2.3 2 0 0 2 2 2 2 Intermediate filament protein TPR_MLP1_2 PF07926.7 GAO85305.1 - 0.0095 15.6 14.5 0.0095 15.6 10.1 4.0 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 GAO85305.1 - 0.27 11.5 16.5 9.6 6.5 0.7 4.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 GAO85305.1 - 0.47 10.0 11.3 0.34 10.5 0.2 4.5 4 1 0 4 4 4 0 Heat shock factor binding protein 1 Tropomyosin_1 PF12718.2 GAO85305.1 - 0.64 9.8 63.0 0.23 11.3 11.0 5.0 2 2 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 GAO85305.1 - 0.73 8.9 6.2 0.59 9.2 0.3 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 GAO85305.1 - 4.5 6.6 43.7 5.3 6.4 13.4 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Cast PF10174.4 GAO85305.1 - 5.1 5.0 52.0 0.9 7.5 16.1 2.6 2 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone DUF869 PF05911.6 GAO85305.1 - 9.1 4.3 43.4 3.2 5.8 14.9 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Fungal_trans PF04082.13 GAO85307.1 - 3e-18 65.6 0.1 5.6e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85307.1 - 1.3e-07 31.4 11.8 2.3e-07 30.6 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 GAO85307.1 - 0.3 10.8 1.8 25 4.7 1.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Methyltransf_23 PF13489.1 GAO85309.1 - 1.5e-27 96.3 0.0 2e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO85309.1 - 9.1e-09 35.6 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85309.1 - 9.3e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85309.1 - 5.1e-05 23.6 0.0 0.0002 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85309.1 - 5.3e-05 23.7 0.0 0.00014 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO85309.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO85309.1 - 0.0067 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO85309.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 GAO85310.1 - 1.1e-39 136.3 0.2 1.4e-39 136.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO85310.1 - 6.4e-05 21.9 0.0 8.7e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAO85310.1 - 0.038 13.7 0.4 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO85310.1 - 0.066 13.0 0.0 0.36 10.6 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.16 GAO85311.1 - 4.6e-70 231.0 0.1 4.4e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 GAO85311.1 - 0.00012 22.0 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 GAO85311.1 - 0.024 14.9 0.2 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) ETF_QO PF05187.8 GAO85312.1 - 4.2e-45 152.2 0.0 6.7e-45 151.6 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase RRM_1 PF00076.17 GAO85312.1 - 7.5e-16 57.5 0.1 7e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85312.1 - 1.5e-10 40.9 0.0 4e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85312.1 - 4.1e-08 32.9 0.0 0.0014 18.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 GAO85312.1 - 5.4e-08 32.1 0.2 0.00093 18.1 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO85312.1 - 5e-07 28.9 0.4 0.0012 17.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO85312.1 - 1e-06 28.6 0.0 2.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO85312.1 - 0.00024 21.0 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO85312.1 - 0.00037 19.6 0.0 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO85312.1 - 0.00042 18.8 0.6 0.00064 18.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 GAO85312.1 - 0.00048 19.2 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO85312.1 - 0.00054 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO85312.1 - 0.00091 18.3 0.0 0.0041 16.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 GAO85312.1 - 0.0022 17.8 0.3 0.0064 16.2 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO85312.1 - 0.0046 17.3 0.1 6.1 7.3 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 GAO85312.1 - 0.022 15.1 0.7 0.063 13.6 0.5 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 GAO85312.1 - 0.092 11.6 0.3 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 GAO85312.1 - 0.16 10.5 0.1 0.35 9.4 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 GAO85312.1 - 0.23 10.2 0.5 0.34 9.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FolB PF02152.13 GAO85313.1 - 2.3e-24 85.7 0.0 4.2e-20 71.9 0.1 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase FeThRed_B PF02943.10 GAO85313.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Pkinase PF00069.20 GAO85314.1 - 6.1e-65 218.9 0.0 7.8e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85314.1 - 1.1e-28 100.0 0.0 1.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85314.1 - 0.022 13.7 0.0 0.053 12.4 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Cyclin_N PF00134.18 GAO85315.1 - 6.3e-17 61.3 1.4 1.6e-16 60.0 0.1 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAO85315.1 - 2.2e-08 34.0 0.2 1.2e-05 25.2 0.0 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 GAO85315.1 - 0.00031 20.4 2.4 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat EAF PF09816.4 GAO85316.1 - 1.2e-24 86.3 0.1 2.2e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor APO_RNA-bind PF05634.6 GAO85316.1 - 1.6 7.8 3.4 2.8 7.0 2.3 1.2 1 0 0 1 1 1 0 APO RNA-binding Dor1 PF04124.7 GAO85317.1 - 3.7e-56 190.0 4.7 2e-44 151.4 2.5 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 GAO85317.1 - 9.1e-06 25.4 1.5 3.2e-05 23.6 1.1 2.0 1 0 0 1 1 1 1 Vps51/Vps67 ApoLp-III PF07464.6 GAO85317.1 - 0.021 14.8 1.4 0.11 12.4 0.3 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) His_Phos_1 PF00300.17 GAO85318.1 - 4.6e-33 114.5 0.0 1.2e-32 113.1 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ebola_NP PF05505.7 GAO85318.1 - 7.3 4.5 18.5 14 3.5 12.8 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein Cyclin PF08613.6 GAO85319.1 - 1.8e-14 54.4 0.0 2.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAO85319.1 - 0.0074 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fork_head PF00250.13 GAO85320.1 - 9.1e-17 60.8 0.0 1.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAO85320.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.1 GAO85321.1 - 4.7e-11 43.0 0.1 7.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAO85321.1 - 8.6e-07 28.5 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAO85321.1 - 0.00051 20.2 0.0 0.00088 19.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.24 GAO85322.1 - 6.1e-44 147.7 0.0 9.1e-24 83.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Glyco_hydro_4C PF11975.3 GAO85323.1 - 0.12 12.1 1.2 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Sigma_reg_N PF13800.1 GAO85324.1 - 0.019 14.9 0.2 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2140 PF09911.4 GAO85324.1 - 0.038 13.1 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3951 PF13131.1 GAO85324.1 - 0.046 13.4 0.4 0.076 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF2500 PF10694.4 GAO85324.1 - 0.054 13.4 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Brr6_like_C_C PF10104.4 GAO85324.1 - 0.07 12.6 0.2 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DC_STAMP PF07782.8 GAO85324.1 - 0.08 12.5 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein DUF1035 PF06281.7 GAO85324.1 - 1.1 9.0 5.2 1.6 8.5 3.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1035) VIT1 PF01988.14 GAO85325.1 - 1.6e-59 200.9 2.8 2e-59 200.6 1.9 1.1 1 0 0 1 1 1 1 VIT family Abhydrolase_9_N PF15420.1 GAO85325.1 - 0.077 12.7 0.4 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PAP2 PF01569.16 GAO85326.1 - 9.7e-16 57.6 5.6 9.7e-16 57.6 3.9 2.0 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 GAO85326.1 - 1.3e-07 31.3 5.7 3.7e-07 29.8 4.0 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 GAO85326.1 - 0.49 10.7 5.4 0.33 11.2 1.4 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal LCAT PF02450.10 GAO85327.1 - 1.4e-94 317.3 0.0 1.7e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HutD PF05962.6 GAO85327.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 HutD Lipase_2 PF01674.13 GAO85327.1 - 0.034 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.2 GAO85327.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO85327.1 - 0.078 12.8 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 GAO85328.1 - 6.6e-19 67.7 0.1 1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO85328.1 - 8.6e-12 44.6 0.1 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAO85328.1 - 6.2e-10 39.1 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO85328.1 - 8.2e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO85328.1 - 1.3e-09 38.3 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAO85328.1 - 1.4e-08 34.7 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO85328.1 - 9.1e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO85328.1 - 0.00028 20.7 0.0 0.00078 19.2 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 GAO85328.1 - 0.00068 18.5 0.3 0.0014 17.5 0.0 1.5 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_4 PF13420.1 GAO85328.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAO85328.1 - 0.029 13.9 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_3 PF13812.1 GAO85329.1 - 0.0052 16.9 0.1 3 8.3 0.0 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAO85329.1 - 0.021 14.7 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family Pex24p PF06398.6 GAO85330.1 - 4.7e-06 25.6 4.4 7.5e-06 24.9 3.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3584 PF12128.3 GAO85330.1 - 0.024 12.0 0.1 0.033 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1700 PF08006.6 GAO85330.1 - 0.22 10.8 0.1 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Mis14 PF08641.7 GAO85331.1 - 1.7e-39 135.0 1.1 6.7e-39 133.1 0.8 2.0 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Nop53 PF07767.6 GAO85331.1 - 0.0013 17.7 1.0 0.0015 17.5 0.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.4 GAO85331.1 - 0.0019 17.0 3.3 0.0025 16.5 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Endomucin PF07010.7 GAO85331.1 - 0.06 12.6 0.1 0.085 12.1 0.1 1.1 1 0 0 1 1 1 0 Endomucin DUF2890 PF11081.3 GAO85331.1 - 0.16 11.9 5.4 0.25 11.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4611 PF15387.1 GAO85331.1 - 2 8.6 7.3 16 5.7 4.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) CRAL_TRIO PF00650.15 GAO85332.1 - 4.1e-38 130.3 0.0 7.2e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO85332.1 - 3.9e-11 42.9 2.6 4.4e-11 42.7 0.4 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAO85332.1 - 6e-06 26.2 0.0 1.8e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 GAO85333.1 - 6e-56 189.2 0.1 6e-56 189.2 0.1 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAO85333.1 - 3.5e-33 114.2 5.3 3.5e-33 114.2 3.7 2.9 3 0 0 3 3 3 1 RasGAP C-terminus PTPLA PF04387.9 GAO85334.1 - 3.4e-44 150.1 9.5 1.1e-43 148.5 6.6 1.8 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DNA_pol_A_exo1 PF01612.15 GAO85335.1 - 1.6e-41 141.6 0.1 2.4e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 GAO85335.1 - 9.1e-27 93.2 0.1 4.3e-26 91.0 0.1 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 GAO85335.1 - 1.1e-11 44.2 0.2 3.2e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 HRDC domain Gpi1 PF05024.10 GAO85336.1 - 9.4e-62 208.0 8.5 1.9e-61 207.0 5.9 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.16 GAO85337.1 - 1.3e-94 315.9 0.0 2.1e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO85337.1 - 3.9e-41 141.0 2.0 7e-41 140.2 1.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 GAO85337.1 - 9.7e-20 71.0 0.6 1.8e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAO85337.1 - 1.1e-17 63.9 2.3 1.9e-17 63.2 0.5 2.4 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 GAO85337.1 - 4.2e-15 55.7 0.0 2.3e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I dTMP_synthase PF02593.9 GAO85338.1 - 0.052 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase VPS28 PF03997.7 GAO85339.1 - 0.019 14.5 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 VPS28 protein DUF2884 PF11101.3 GAO85339.1 - 0.049 13.0 0.9 0.074 12.4 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Terminase_2 PF03592.11 GAO85339.1 - 0.072 13.3 1.6 0.11 12.8 1.1 1.3 1 0 0 1 1 1 0 Terminase small subunit DUF883 PF05957.8 GAO85339.1 - 0.47 10.8 4.8 0.5 10.7 1.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-C2H2_4 PF13894.1 GAO85340.1 - 3e-06 27.1 12.7 0.0006 19.9 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO85340.1 - 5.8e-06 26.3 4.0 5.8e-06 26.3 2.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAO85340.1 - 1.6e-05 24.9 11.7 0.0068 16.6 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glycoprotein_G PF00802.14 GAO85340.1 - 0.15 11.1 2.4 0.36 9.9 1.7 1.6 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G zf-C2H2_6 PF13912.1 GAO85340.1 - 2.9 7.9 5.8 0.32 10.9 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger COG5 PF10392.4 GAO85341.1 - 3.6e-40 136.9 3.4 5e-40 136.5 0.5 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Aldolase_II PF00596.16 GAO85342.1 - 2.1e-46 157.8 0.1 2.8e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SYS1 PF09801.4 GAO85343.1 - 4.6e-54 182.3 7.2 6e-54 181.9 5.0 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TrbE PF11100.3 GAO85343.1 - 6.5 6.6 7.8 1.3 8.9 0.5 2.5 2 0 0 2 2 2 0 Conjugal transfer protein TrbE COX6B PF02297.12 GAO85344.1 - 9.3e-25 86.4 3.7 1.2e-24 86.1 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 GAO85344.1 - 0.032 14.3 0.6 0.055 13.6 0.4 1.4 1 1 0 1 1 1 0 Prolamin-like RRM_1 PF00076.17 GAO85345.1 - 7.1e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85345.1 - 1.2e-05 25.1 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85345.1 - 0.099 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 GAO85346.1 - 3.5e-16 59.0 1.5 5.7e-16 58.3 1.0 1.4 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 GAO85346.1 - 0.00084 19.4 0.4 0.0014 18.6 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4391 PF14335.1 GAO85346.1 - 0.12 11.7 3.9 0.46 9.8 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) U3_assoc_6 PF08640.6 GAO85347.1 - 2.5e-29 100.8 1.0 5.5e-29 99.7 0.7 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 GAO85347.1 - 0.0039 16.9 1.6 2.2 7.9 0.3 2.5 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAO85347.1 - 0.0056 17.2 0.3 0.16 12.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 GAO85347.1 - 0.019 13.8 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.4 GAO85348.1 - 2.9e-43 147.8 6.3 2.9e-43 147.8 4.4 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 GAO85348.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CPSF100_C PF13299.1 GAO85350.1 - 4.1e-45 153.8 1.1 5.2e-45 153.5 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 GAO85350.1 - 7.7e-29 100.1 0.0 1.8e-27 95.8 0.0 2.6 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 GAO85350.1 - 0.00017 21.3 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase PGM_PMM_IV PF00408.15 GAO85350.1 - 0.0023 17.9 0.0 0.0067 16.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.1 GAO85351.1 - 5.7e-52 176.6 46.0 7e-52 176.3 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO85351.1 - 4.4e-19 68.1 41.4 5.9e-19 67.7 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_1 PF04531.8 GAO85351.1 - 0.08 13.0 0.4 1.1 9.3 0.2 2.9 2 0 0 2 2 2 0 Bacteriophage holin DUF4064 PF13273.1 GAO85351.1 - 0.92 9.6 17.3 0.61 10.2 0.7 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) Sec23_trunk PF04811.10 GAO85352.1 - 1.5e-56 191.5 0.0 2.9e-56 190.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAO85352.1 - 1.3e-26 91.9 0.0 2.4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAO85352.1 - 1.9e-18 66.7 0.0 3.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAO85352.1 - 4.4e-17 61.3 6.5 9.9e-17 60.2 4.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAO85352.1 - 6.4e-09 35.3 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 GAO85352.1 - 0.049 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF1678 PF07913.6 GAO85352.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Acp26Ab PF05777.7 GAO85353.1 - 0.044 14.2 0.1 0.068 13.6 0.1 1.3 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) ABC2_membrane PF01061.19 GAO85354.1 - 2.7e-50 170.4 28.9 6.8e-30 103.8 8.9 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAO85354.1 - 5.4e-50 169.2 0.1 3.6e-25 88.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO85354.1 - 8.6e-17 62.0 5.4 1e-07 32.2 1.3 4.3 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAO85354.1 - 4.6e-10 38.8 0.2 0.00051 19.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO85354.1 - 5.1e-09 35.8 0.0 0.0068 15.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.1 GAO85354.1 - 7.4e-09 35.1 0.0 0.55 9.2 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 GAO85354.1 - 1e-08 35.7 0.1 0.00027 21.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAO85354.1 - 1.2e-08 34.4 1.8 0.0011 18.3 0.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAO85354.1 - 1.7e-08 34.6 0.1 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAO85354.1 - 9.6e-07 28.2 1.8 0.022 14.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAO85354.1 - 3.2e-06 27.3 1.2 0.077 13.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAO85354.1 - 4.9e-06 27.3 0.2 0.033 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 GAO85354.1 - 1.7e-05 24.6 0.1 0.0059 16.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 GAO85354.1 - 4e-05 23.5 0.4 0.13 12.1 0.0 3.7 4 0 0 4 4 3 1 AAA domain NACHT PF05729.7 GAO85354.1 - 5.6e-05 22.8 0.3 0.048 13.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 GAO85354.1 - 8.9e-05 22.6 0.4 0.49 10.6 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 GAO85354.1 - 0.00012 22.5 0.7 0.23 11.9 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 GAO85354.1 - 0.00014 21.5 0.3 0.22 11.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 GAO85354.1 - 0.00031 20.4 1.7 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAO85354.1 - 0.00039 20.4 0.4 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAO85354.1 - 0.00045 19.8 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAO85354.1 - 0.00051 19.9 2.4 0.24 11.3 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 GAO85354.1 - 0.00057 20.1 0.4 0.2 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAO85354.1 - 0.00069 19.1 3.4 0.13 11.6 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 GAO85354.1 - 0.0016 18.5 0.2 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 GAO85354.1 - 0.0029 17.1 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 GAO85354.1 - 0.0033 16.9 6.9 0.2 11.0 0.3 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_24 PF13479.1 GAO85354.1 - 0.0053 16.3 0.3 0.92 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAO85354.1 - 0.0072 15.2 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein UPF0079 PF02367.12 GAO85354.1 - 0.0074 15.9 0.9 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 GAO85354.1 - 0.0076 16.1 0.6 7.1 6.6 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 GAO85354.1 - 0.0078 15.9 1.5 0.89 9.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 GAO85354.1 - 0.013 14.5 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 GAO85354.1 - 0.014 15.0 2.7 3.8 7.1 0.0 3.4 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.7 GAO85354.1 - 0.018 14.1 1.8 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 GAO85354.1 - 0.019 14.8 1.3 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Dynamin family PDR_CDR PF06422.7 GAO85354.1 - 0.028 14.0 0.1 0.083 12.5 0.1 1.7 1 0 0 1 1 1 0 CDR ABC transporter ATP-synt_ab PF00006.20 GAO85354.1 - 0.042 13.3 0.1 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 GAO85354.1 - 0.049 13.1 1.3 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 GAO85354.1 - 0.061 12.5 1.9 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_35 PF14516.1 GAO85354.1 - 0.067 11.8 0.2 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 GAO85354.1 - 0.078 11.9 0.7 2.2 7.1 0.2 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_14 PF13173.1 GAO85354.1 - 0.078 12.8 0.8 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 GAO85354.1 - 0.11 11.7 0.3 7 5.8 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein PRK PF00485.13 GAO85354.1 - 0.17 11.3 1.4 12 5.3 0.3 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 GAO85354.1 - 0.23 10.9 1.9 10 5.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 GAO85354.1 - 0.25 10.5 1.5 9 5.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 GAO85354.1 - 1.7 8.0 3.2 16 4.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 GAO85354.1 - 2.5 7.8 5.2 24 4.6 1.1 3.2 4 0 0 4 4 2 0 Domain of unknown function DUF87 DUF2627 PF11118.3 GAO85354.1 - 3.2 7.9 7.4 6.3 6.9 0.2 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF2627) Fungal_trans_2 PF11951.3 GAO85355.1 - 1.5e-59 201.5 0.1 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85355.1 - 5.7e-09 35.7 10.6 8.7e-09 35.1 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 GAO85355.1 - 0.33 10.7 6.8 1.1 9.1 4.7 2.0 1 0 0 1 1 1 0 AT hook motif DUF2434 PF10361.4 GAO85356.1 - 1.5e-130 434.6 1.4 1.8e-130 434.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Cation_ATPase_C PF00689.16 GAO85356.1 - 0.00026 20.5 0.7 0.00026 20.5 0.5 2.3 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Gti1_Pac2 PF09729.4 GAO85357.1 - 7.8e-49 165.7 5.0 1.3e-47 161.7 0.9 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 GAO85358.1 - 9.9e-56 188.9 0.0 4.9e-55 186.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAO85358.1 - 4.2e-06 26.5 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 GAO85358.1 - 0.0056 16.1 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA_anti-like RRM_1 PF00076.17 GAO85359.1 - 8.8e-14 50.9 0.0 1.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85359.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_PEP_C PF04513.7 GAO85359.1 - 0.0043 16.8 0.7 0.0095 15.7 0.5 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_5 PF13893.1 GAO85359.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 GAO85360.1 - 1.3e-56 190.8 0.0 1.2e-55 187.7 0.0 2.0 1 1 0 1 1 1 1 MOZ/SAS family Nop PF01798.13 GAO85361.1 - 2.2e-60 202.3 0.1 2.2e-60 202.3 0.1 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 GAO85361.1 - 5.9e-25 86.8 0.4 1.3e-24 85.7 0.3 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAO85361.1 - 3.4e-22 78.3 0.0 3.4e-22 78.3 0.0 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain YL1 PF05764.8 GAO85361.1 - 0.35 10.4 29.0 0.52 9.8 20.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RP-C_C PF11800.3 GAO85361.1 - 7.8 6.1 11.5 38 3.8 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Cpn60_TCP1 PF00118.19 GAO85362.1 - 1.1e-149 499.1 0.1 1.3e-149 498.9 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3767 PF12597.3 GAO85364.1 - 4.7e-39 132.6 0.2 4.7e-39 132.6 0.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) Ribosomal_S4 PF00163.14 GAO85364.1 - 0.047 14.0 3.9 0.11 12.8 2.7 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Erv26 PF04148.8 GAO85364.1 - 0.17 11.2 0.0 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 Transmembrane adaptor Erv26 TEX13 PF15186.1 GAO85364.1 - 0.34 10.4 4.3 1.2 8.7 2.7 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family HAND PF09110.6 GAO85364.1 - 3.1 8.2 7.9 2.3 8.6 2.4 2.2 2 1 0 2 2 2 0 HAND DUF1744 PF08490.7 GAO85365.1 - 2.2e-154 513.8 0.1 3.2e-154 513.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 GAO85365.1 - 4.8e-71 239.2 0.3 5e-70 235.9 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 GAO85365.1 - 9.7e-23 80.6 0.0 2.3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 GAO85365.1 - 1.6e-08 34.3 0.0 5.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 GAO85365.1 - 4.6e-05 23.2 0.1 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Pkinase PF00069.20 GAO85366.1 - 6.6e-71 238.5 0.0 8.5e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85366.1 - 2.4e-30 105.5 0.0 3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85366.1 - 1.4e-06 27.4 0.0 3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAO85366.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO85366.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO85366.1 - 0.015 14.6 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 GAO85367.1 - 1e-41 141.9 0.0 1.9e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 DUF822 PF05687.8 GAO85367.1 - 0.3 11.4 5.8 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) TFIIF_alpha PF05793.7 GAO85367.1 - 3.6 5.8 9.4 4.7 5.4 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RAP1 PF07218.6 GAO85367.1 - 5.8 4.8 9.1 7.4 4.5 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SGT1 PF07093.6 GAO85368.1 - 2.1e-156 521.7 27.2 1.3e-154 515.9 18.9 2.0 1 1 0 1 1 1 1 SGT1 protein eIF-1a PF01176.14 GAO85368.1 - 0.041 13.3 0.0 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 Microtub_assoc PF07989.6 GAO85369.1 - 3.5e-28 97.2 7.7 3.5e-28 97.2 5.3 11.9 8 4 8 16 16 16 1 Microtubule associated PACT_coil_coil PF10495.4 GAO85369.1 - 6.7e-26 90.0 1.4 2.1e-25 88.4 1.0 1.9 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.3 GAO85369.1 - 0.00025 20.7 17.5 0.00025 20.7 12.1 15.5 6 5 9 16 16 16 3 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 GAO85369.1 - 0.0024 16.4 127.2 0.0081 14.6 19.2 5.2 1 1 3 5 5 5 4 AAA domain GAS PF13851.1 GAO85369.1 - 0.0028 16.8 23.0 0.0028 16.8 15.9 9.5 2 1 7 9 9 9 4 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 GAO85369.1 - 4.8 6.2 50.2 0.21 10.7 1.9 7.1 2 1 5 8 8 8 0 Reovirus sigma C capsid protein AAA PF00004.24 GAO85370.1 - 2.7e-42 144.0 0.0 5.6e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAO85370.1 - 3.2e-28 97.3 0.0 1.4e-27 95.3 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAO85370.1 - 2e-22 78.8 1.6 2e-22 78.8 1.1 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 GAO85370.1 - 5.7e-07 30.3 0.0 1.1e-05 26.2 0.0 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAO85370.1 - 1.1e-05 24.6 0.0 1.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAO85370.1 - 1.2e-05 25.4 0.1 0.0013 18.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO85370.1 - 1.4e-05 24.8 0.0 8.7e-05 22.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAO85370.1 - 2.7e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 GAO85370.1 - 3.4e-05 23.9 0.0 0.0091 16.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 GAO85370.1 - 5.2e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAO85370.1 - 5.4e-05 22.2 0.0 0.00094 18.1 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 GAO85370.1 - 0.00011 22.2 0.0 0.0015 18.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 GAO85370.1 - 0.00012 20.8 0.0 0.00023 20.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 GAO85370.1 - 0.00021 20.7 0.1 0.19 11.1 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 GAO85370.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAO85370.1 - 0.00071 19.5 0.0 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 GAO85370.1 - 0.0038 17.5 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAO85370.1 - 0.0072 15.9 0.0 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAO85370.1 - 0.013 15.1 0.2 0.26 10.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 GAO85370.1 - 0.015 14.5 0.0 0.058 12.5 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAO85370.1 - 0.021 13.9 0.1 0.14 11.1 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 GAO85370.1 - 0.022 14.5 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 GAO85370.1 - 0.025 14.2 0.0 0.63 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 GAO85370.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Torsin PF06309.6 GAO85370.1 - 0.03 14.1 0.1 0.079 12.8 0.0 1.7 2 0 0 2 2 1 0 Torsin PhoH PF02562.11 GAO85370.1 - 0.041 13.1 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 GAO85370.1 - 0.046 12.5 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 GAO85370.1 - 0.089 11.8 0.1 7.3 5.6 0.0 2.8 2 1 1 3 3 3 0 KaiC CPT PF07931.7 GAO85370.1 - 0.097 12.2 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAO85370.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 GAO85371.1 - 6.9e-20 70.7 15.4 8.8e-20 70.4 10.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 GAO85371.1 - 0.00042 20.0 4.1 0.00083 19.0 2.8 1.5 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 GAO85371.1 - 0.0022 17.5 12.5 0.0056 16.3 8.6 1.6 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 GAO85371.1 - 0.0071 15.9 12.6 0.12 11.9 8.7 2.1 1 1 0 1 1 1 1 Prefoldin subunit COG2 PF06148.6 GAO85371.1 - 0.011 15.5 4.5 0.062 13.1 0.6 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 GAO85371.1 - 0.023 14.5 12.0 0.16 11.8 3.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hemagglutinin PF00509.13 GAO85371.1 - 0.026 12.6 0.6 0.028 12.5 0.4 1.2 1 0 0 1 1 1 0 Haemagglutinin Spc7 PF08317.6 GAO85371.1 - 0.028 13.0 9.7 0.036 12.7 6.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.6 GAO85371.1 - 0.029 11.9 2.9 0.03 11.8 2.0 1.0 1 0 0 1 1 1 0 Prominin AAA_27 PF13514.1 GAO85371.1 - 0.036 11.7 9.6 0.036 11.7 6.6 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 GAO85371.1 - 0.049 12.5 7.7 0.054 12.4 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 GAO85371.1 - 0.2 11.4 9.5 0.9 9.3 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 GAO85371.1 - 0.22 11.2 10.9 0.5 10.0 0.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 GAO85371.1 - 0.25 11.2 11.9 0.42 10.4 2.9 2.1 2 0 0 2 2 2 0 Tropomyosin like Sas10_Utp3 PF04000.10 GAO85371.1 - 0.25 11.5 3.5 0.68 10.1 0.2 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF972 PF06156.8 GAO85371.1 - 0.29 11.4 8.7 4.5 7.6 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Streptin-Immun PF11083.3 GAO85371.1 - 0.61 10.1 5.3 2.5 8.1 1.1 2.3 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein NPV_P10 PF05531.7 GAO85371.1 - 0.67 10.2 5.3 4.6 7.5 0.4 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ERp29 PF07749.7 GAO85371.1 - 0.73 10.4 4.5 1.4 9.6 3.1 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain OmpH PF03938.9 GAO85371.1 - 1.1 9.1 19.3 2.5 8.0 13.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Siah-Interact_N PF09032.6 GAO85371.1 - 1.4 9.0 11.0 2.4 8.2 0.7 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal TcdA_TcdB PF12919.2 GAO85371.1 - 1.5 7.1 6.0 2.3 6.6 4.2 1.3 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain FliD_N PF02465.13 GAO85371.1 - 1.7 9.0 6.7 0.64 10.4 0.1 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.4 GAO85371.1 - 2.3 8.4 8.2 2.1 8.5 0.4 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lzipper-MIP1 PF14389.1 GAO85371.1 - 3 8.0 12.3 2.5 8.2 0.4 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 GAO85371.1 - 3.1 6.7 11.9 12 4.8 8.2 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Rootletin PF15035.1 GAO85371.1 - 3.2 7.6 11.4 21 5.0 7.9 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.1 GAO85371.1 - 4.2 7.3 15.3 8.7 6.3 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.8 GAO85371.1 - 5.1 7.8 7.8 6.2 7.6 0.8 2.2 1 1 1 2 2 2 0 Occludin homology domain Mnd1 PF03962.10 GAO85371.1 - 5.2 6.7 13.5 3.3 7.3 4.1 2.1 1 1 1 2 2 2 0 Mnd1 family GrpE PF01025.14 GAO85371.1 - 5.9 6.3 11.1 4.5 6.8 3.6 2.1 2 0 0 2 2 2 0 GrpE DUF3847 PF12958.2 GAO85371.1 - 6.8 6.5 9.8 12 5.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) AAA_13 PF13166.1 GAO85371.1 - 8.6 4.6 12.4 44 2.3 8.5 1.8 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 GAO85371.1 - 9.9 5.9 14.3 4.4 7.0 4.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PDCD2_C PF04194.8 GAO85372.1 - 1e-56 191.0 0.0 5e-56 188.8 0.0 2.1 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Prenylcys_lyase PF07156.9 GAO85373.1 - 1.7e-40 139.0 0.0 2.7e-39 135.1 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 GAO85373.1 - 6.6e-13 48.4 0.0 1.4e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAO85373.1 - 1.2e-09 37.7 0.0 0.00013 21.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAO85373.1 - 3.5e-05 23.6 0.1 0.00043 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 GAO85373.1 - 9.4e-05 21.4 0.1 9.4e-05 21.4 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO85373.1 - 0.018 14.8 0.1 0.078 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO85373.1 - 0.026 14.9 0.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO85373.1 - 0.17 10.3 0.1 3.2 6.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein SHMT PF00464.14 GAO85374.1 - 5.8e-208 690.0 0.0 6.8e-208 689.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 GAO85374.1 - 0.00015 20.6 0.0 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO85374.1 - 0.007 15.5 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3040 PF11239.3 GAO85374.1 - 0.036 14.1 0.2 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Med9 PF07544.8 GAO85375.1 - 7e-26 89.7 0.2 1e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 GAO85375.1 - 0.0015 18.4 4.1 0.0022 17.9 2.8 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TMF_DNA_bd PF12329.3 GAO85375.1 - 0.043 13.6 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 GAO85375.1 - 0.087 12.9 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 GAO85375.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 SlyX Metalloenzyme PF01676.13 GAO85376.1 - 2.2e-71 240.2 0.1 2.5e-71 240.0 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 GAO85376.1 - 3.9e-71 238.9 0.0 5.2e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 GAO85376.1 - 8.9e-11 41.7 0.1 6.5e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAO85376.1 - 4.4e-06 26.1 0.0 0.00067 18.9 0.0 3.0 2 1 0 2 2 2 1 Sulfatase AP_endonuc_2 PF01261.19 GAO85376.1 - 0.025 13.8 0.0 0.079 12.2 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Alk_phosphatase PF00245.15 GAO85376.1 - 0.027 13.1 0.1 0.2 10.3 0.0 2.0 2 0 0 2 2 2 0 Alkaline phosphatase PCI_Csn8 PF10075.4 GAO85377.1 - 4.6e-48 162.6 0.0 6.3e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAO85377.1 - 1.2e-23 83.7 0.2 1.6e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Glyco_hydro_92 PF07971.7 GAO85378.1 - 1.2e-158 528.9 1.6 1.5e-158 528.5 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bacteriocin_IIc PF10439.4 GAO85379.1 - 0.13 12.4 7.1 0.18 11.9 4.9 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Glyco_hydro_16 PF00722.16 GAO85380.1 - 2.9e-40 137.5 9.0 5.3e-40 136.6 6.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CoA_transf_3 PF02515.12 GAO85381.1 - 8.6e-42 142.5 1.7 2.3e-38 131.3 0.7 2.2 2 0 0 2 2 2 2 CoA-transferase family III Methyltransf_23 PF13489.1 GAO85382.1 - 0.00013 21.6 0.0 0.00036 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85382.1 - 0.00016 21.3 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAO85382.1 - 0.00028 21.3 0.1 0.0059 17.0 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85382.1 - 0.0015 18.9 0.1 0.024 15.1 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85382.1 - 0.015 15.8 0.4 8 7.0 0.0 2.8 2 1 1 3 3 3 0 Methyltransferase domain RA PF00788.18 GAO85382.1 - 0.15 12.5 0.0 0.49 10.9 0.0 1.9 1 1 1 2 2 2 0 Ras association (RalGDS/AF-6) domain COesterase PF00135.23 GAO85383.1 - 1.2e-79 268.4 3.6 2.2e-79 267.5 2.5 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO85383.1 - 0.00029 20.4 0.0 0.00074 19.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO85383.1 - 0.006 15.8 0.1 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO85383.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 GAO85384.1 - 4.6e-82 275.9 0.0 5.9e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 GAO85384.1 - 1.7e-30 106.1 0.0 2.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAO85384.1 - 1.6e-25 89.7 0.0 7.5e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 GAO85384.1 - 1.1e-11 45.2 0.0 4.4e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAO85384.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain DUF550 PF04447.7 GAO85384.1 - 0.041 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Exo_endo_phos PF03372.18 GAO85385.1 - 2.1e-12 47.5 0.2 3.2e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAO85385.1 - 0.082 12.5 0.0 0.49 10.0 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase F-box-like PF12937.2 GAO85386.1 - 1.1e-07 31.4 0.0 3.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 F-box-like MdcG PF10620.4 GAO85387.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF848 PF05852.6 GAO85387.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Aldo_ket_red PF00248.16 GAO85388.1 - 2e-62 210.5 0.0 3e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 GAO85389.1 - 7.9e-38 130.0 20.1 7.9e-38 130.0 13.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO85389.1 - 7.6e-13 47.8 18.7 1.1e-12 47.2 13.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hyd_65N_2 PF14498.1 GAO85391.1 - 1.3e-48 165.7 0.0 1.9e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain adh_short_C2 PF13561.1 GAO85391.1 - 2.6e-22 79.7 0.5 3.8e-22 79.2 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO85391.1 - 2.9e-20 72.8 7.1 2.9e-20 72.8 4.9 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO85391.1 - 0.00014 21.5 5.0 0.00033 20.3 3.5 1.5 1 0 0 1 1 1 1 KR domain Glyco_hydro_65m PF03632.10 GAO85391.1 - 0.0094 14.6 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Suc_Fer-like PF06999.7 GAO85392.1 - 3.8e-45 154.6 0.0 6.9e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hydro_43 PF04616.9 GAO85392.1 - 4.2e-32 111.3 2.7 6.2e-32 110.8 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 GAO85392.1 - 3.3e-11 42.5 0.3 5.9e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85392.1 - 5.3e-09 35.8 7.1 1.5e-08 34.3 4.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drc1-Sld2 PF11719.3 GAO85393.1 - 1.3e-147 492.3 27.6 1.7e-147 492.0 19.1 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.1 GAO85394.1 - 3.9e-09 36.1 5.1 6.3e-09 35.5 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAO85394.1 - 1.6e-07 31.2 5.3 2.5e-07 30.6 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO85394.1 - 2.2e-07 30.3 4.1 3.4e-07 29.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO85394.1 - 1.4e-06 28.3 4.0 3.4e-06 27.0 2.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAO85394.1 - 2.5e-06 27.0 3.6 3.6e-06 26.5 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO85394.1 - 0.028 14.1 2.8 0.046 13.4 1.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 GAO85394.1 - 0.088 12.6 0.9 0.2 11.5 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Coronavirus_5 PF05528.6 GAO85394.1 - 0.094 12.5 0.0 1.1 9.1 0.0 2.5 2 1 0 2 2 2 0 Coronavirus gene 5 protein zf-C3HC4_4 PF15227.1 GAO85394.1 - 0.11 12.3 5.2 0.19 11.6 3.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 GAO85394.1 - 0.21 11.1 3.5 0.35 10.4 2.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 GAO85394.1 - 0.27 10.7 1.8 0.5 9.9 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2410 PF10307.4 GAO85395.1 - 6.2e-86 286.8 0.0 8.9e-86 286.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) COesterase PF00135.23 GAO85396.1 - 6.9e-86 289.0 0.0 1.4e-85 288.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO85396.1 - 1.1e-08 34.8 0.0 3.9e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO85396.1 - 0.0012 18.5 0.1 0.0068 16.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2877 PF11392.3 GAO85396.1 - 0.1 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) HAUS5 PF14817.1 GAO85396.1 - 0.13 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Peptidase_S9 PF00326.16 GAO85396.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fig1 PF12351.3 GAO85397.1 - 1.2e-59 201.2 7.3 1.2e-59 201.2 5.1 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 GAO85397.1 - 2.4e-09 37.0 3.1 4.4e-09 36.2 2.1 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 GAO85397.1 - 7.3e-06 25.1 6.0 7.3e-06 25.1 4.2 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) XPG_I PF00867.13 GAO85398.1 - 2.1e-25 88.5 0.1 4.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAO85398.1 - 6.1e-23 81.0 0.0 2.2e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 GAO85398.1 - 0.00091 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_11 PF13414.1 GAO85398.1 - 0.093 12.3 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 TPR repeat DUF2962 PF11176.3 GAO85399.1 - 8.9e-63 210.4 1.2 1e-62 210.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MAM33 PF02330.11 GAO85400.1 - 4.3e-37 127.8 5.6 1.7e-35 122.6 3.9 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein Kri1 PF05178.7 GAO85400.1 - 0.087 13.1 1.0 0.21 11.8 0.7 1.7 1 0 0 1 1 1 0 KRI1-like family DNA_primase_S PF01896.14 GAO85401.1 - 3.3e-54 182.6 0.1 5.3e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Collagen PF01391.13 GAO85402.1 - 0.64 9.5 10.6 0.16 11.5 4.7 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Adaptin_N PF01602.15 GAO85403.1 - 5.6e-150 500.1 5.4 7.8e-150 499.6 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAO85403.1 - 5.6e-30 104.4 1.6 4.1e-26 91.9 0.1 3.3 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Thr_synth_N PF14821.1 GAO85403.1 - 9.4e-30 102.4 0.0 5.2e-29 100.0 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus HEAT_2 PF13646.1 GAO85403.1 - 1.8e-17 63.3 3.6 4.3e-06 26.9 0.1 6.1 3 1 4 7 7 7 3 HEAT repeats PALP PF00291.20 GAO85403.1 - 2e-15 56.8 0.0 6.3e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HEAT PF02985.17 GAO85403.1 - 4.8e-10 38.6 3.4 0.03 14.3 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 GAO85403.1 - 0.00075 19.9 0.1 3.7 8.1 0.0 5.8 6 1 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 GAO85403.1 - 0.0013 18.1 0.2 3.1 7.0 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 GAO85403.1 - 0.036 13.8 1.1 22 5.0 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3554 PF12074.3 GAO85403.1 - 0.04 13.3 0.3 3.5 6.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3554) EHN PF06441.7 GAO85404.1 - 2e-38 130.7 0.1 3.5e-38 129.9 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 GAO85404.1 - 2e-09 37.3 0.1 6.3e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO85404.1 - 4.7e-09 36.4 0.2 1.5e-08 34.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 GAO85405.1 - 0.00021 21.0 0.2 0.2 11.6 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat SAC3_GANP PF03399.11 GAO85406.1 - 7.7e-23 81.1 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAO85406.1 - 5e-20 71.7 0.0 7.6e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Pro-kuma_activ PF09286.6 GAO85407.1 - 1.8e-41 141.5 0.4 7e-41 139.6 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAO85407.1 - 5.2e-08 32.3 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Subtilase family TBCC PF07986.7 GAO85408.1 - 7.5e-35 118.9 0.2 1.1e-34 118.4 0.2 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C Phytase-like PF13449.1 GAO85410.1 - 3.6e-29 102.0 0.0 5.7e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 GAO85410.1 - 0.042 12.8 0.0 3.7 6.4 0.0 2.5 2 1 0 2 2 2 0 SdiA-regulated SBP_bac_3 PF00497.15 GAO85411.1 - 0.0067 15.6 0.2 0.03 13.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 DEK_C PF08766.6 GAO85411.1 - 0.046 13.4 0.3 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 DEK C terminal domain Evr1_Alr PF04777.8 GAO85412.1 - 6.7e-27 93.2 1.1 6.7e-27 93.2 0.8 1.6 2 0 0 2 2 2 1 Erv1 / Alr family Coatomer_WDAD PF04053.9 GAO85413.1 - 4.4e-152 506.9 0.0 1.4e-151 505.3 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 GAO85413.1 - 2.7e-93 312.8 0.0 4.3e-93 312.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 GAO85413.1 - 1.8e-51 170.2 10.5 2.9e-09 36.4 0.1 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAO85413.1 - 0.0066 14.6 7.5 1.6 6.7 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 GAO85413.1 - 0.035 13.6 0.7 0.67 9.5 0.0 3.0 3 0 0 3 3 3 0 Region in Clathrin and VPS DUF1917 PF08939.5 GAO85414.1 - 6.5e-91 304.4 0.0 7.6e-91 304.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) IF4E PF01652.13 GAO85414.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Cellulase PF00150.13 GAO85415.1 - 6.8e-10 38.6 3.8 6.1e-09 35.4 1.6 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 GAO85416.1 - 9.2e-36 121.3 33.5 5.6e-05 22.6 0.0 12.7 13 1 1 14 14 14 10 TPR repeat TPR_16 PF13432.1 GAO85416.1 - 9e-27 93.1 36.0 1.7e-05 25.3 1.8 12.8 12 2 2 14 14 14 9 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85416.1 - 1.5e-24 84.2 32.2 0.0066 16.9 0.0 16.3 13 5 5 18 18 18 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85416.1 - 7.4e-22 75.4 41.2 0.11 12.4 0.0 16.6 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAO85416.1 - 4.5e-21 74.9 15.4 0.0028 17.9 0.0 12.1 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAO85416.1 - 4.6e-20 70.0 14.5 0.16 12.2 0.0 15.9 19 0 0 19 19 18 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85416.1 - 2.7e-19 68.8 28.0 2.5e-07 30.5 0.2 11.3 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.23 GAO85416.1 - 3.8e-18 64.2 32.2 0.035 13.7 0.0 14.4 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAO85416.1 - 6.6e-14 50.5 21.8 0.25 11.2 0.0 12.7 13 1 1 14 14 13 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAO85416.1 - 2.1e-07 30.9 17.6 0.97 10.0 0.0 11.4 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85416.1 - 1.5e-05 24.4 16.7 0.054 13.3 0.0 11.1 14 1 1 15 15 14 2 Tetratricopeptide repeat Apc3 PF12895.2 GAO85416.1 - 0.0024 17.9 21.9 0.24 11.5 0.0 8.8 9 2 1 11 11 11 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 GAO85416.1 - 0.018 14.9 10.6 35 4.4 0.1 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1767 PF08585.7 GAO85417.1 - 7.5e-23 80.6 0.2 1.1e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 GAO85418.1 - 1e-27 95.7 0.0 2.2e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 GAO85418.1 - 9.6e-06 25.4 0.0 2.5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.4 GAO85418.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 GAO85418.1 - 0.0021 17.0 0.0 0.004 16.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Dor1 PF04124.7 GAO85418.1 - 0.0033 15.9 0.1 0.0047 15.4 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 GAO85418.1 - 0.029 13.1 0.0 0.17 10.5 0.0 1.9 1 1 0 1 1 1 0 Vps53-like, N-terminal Fes1 PF08609.5 GAO85418.1 - 0.079 13.4 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Xpo1 PF08389.7 GAO85419.1 - 1.3e-09 38.1 2.8 1.7e-05 24.7 0.0 3.8 4 0 0 4 4 4 2 Exportin 1-like protein HEAT_2 PF13646.1 GAO85419.1 - 0.048 13.9 0.9 0.35 11.1 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats Arm PF00514.18 GAO85419.1 - 0.077 12.8 0.3 0.44 10.4 0.2 2.3 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat GRIM-19 PF06212.7 GAO85420.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 GAO85421.1 - 2.6e-32 111.9 0.0 1.3e-31 109.6 0.0 2.0 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 GAO85422.1 - 0 1189.7 2.0 0 1189.6 1.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein TLD PF07534.11 GAO85423.1 - 9.1e-25 87.2 0.0 1.7e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 TLD STb_secrete PF09075.5 GAO85423.1 - 0.14 12.0 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory JAB PF01398.16 GAO85424.1 - 1e-14 54.2 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 GAO85424.1 - 9.3e-08 32.0 0.2 1.6e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 GAO85424.1 - 4.8e-06 26.0 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ATG16 PF08614.6 GAO85425.1 - 0.0012 18.7 0.8 0.002 17.9 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlxA PF14282.1 GAO85425.1 - 0.44 10.5 3.9 1.2 9.0 2.0 2.0 1 1 1 2 2 2 0 FlxA-like protein Pkinase PF00069.20 GAO85426.1 - 3.1e-13 49.4 0.0 4.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85426.1 - 5.2e-06 25.7 0.0 9.1e-06 24.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAO85426.1 - 0.036 13.3 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Polyketide_cyc2 PF10604.4 GAO85427.1 - 1.9e-05 24.8 3.6 4.8e-05 23.5 2.5 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 GAO85427.1 - 0.00018 21.5 0.6 0.00033 20.6 0.4 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CRISPR_assoc PF08798.6 GAO85427.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Glyco_hydro_28 PF00295.12 GAO85428.1 - 4.4e-36 124.4 3.2 3.5e-35 121.5 0.8 2.2 2 1 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAO85428.1 - 0.019 14.7 5.7 0.045 13.5 2.0 2.3 1 1 1 2 2 2 0 Right handed beta helix region Iso_dh PF00180.15 GAO85429.1 - 5.6e-65 219.5 0.0 7.6e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Strabismus PF06638.6 GAO85429.1 - 1.2 7.3 5.1 7.1 4.8 0.0 2.2 2 0 0 2 2 2 0 Strabismus protein FTHFS PF01268.14 GAO85430.1 - 1e-255 849.0 0.0 1.4e-255 848.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 GAO85430.1 - 7.5e-68 226.6 0.5 1.7e-67 225.5 0.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAO85430.1 - 5.3e-37 126.4 0.3 1.2e-36 125.3 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 GAO85431.1 - 9.4e-34 114.0 1.3 1.3e-10 40.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAO85431.1 - 0.0011 17.2 0.1 0.0016 16.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 GAO85431.1 - 0.006 16.0 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Pyr_redox_2 PF07992.9 GAO85431.1 - 0.049 13.4 0.0 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MBF1 PF08523.5 GAO85432.1 - 2.8e-25 88.1 1.9 6.2e-25 87.0 1.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 GAO85432.1 - 2.3e-11 43.3 0.0 3.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 GAO85432.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 GAO85432.1 - 0.00055 19.9 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain SH3_1 PF00018.23 GAO85433.1 - 1.6e-13 49.8 0.0 2.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO85433.1 - 1e-10 41.0 0.0 2.5e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 GAO85433.1 - 6.8e-08 31.8 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 GAO85433.1 - 0.45 8.6 12.3 0.52 8.4 8.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.4 GAO85433.1 - 1.4 8.9 6.6 18 5.2 3.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) MCPVI PF02993.9 GAO85433.1 - 2.1 8.4 6.3 3.1 7.8 4.4 1.3 1 0 0 1 1 1 0 Minor capsid protein VI AIM24 PF01987.12 GAO85434.1 - 1.7e-57 194.3 0.1 2.1e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 GAO85435.1 - 1.6e-44 150.5 0.2 3.2e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 GAO85435.1 - 0.12 12.7 0.8 0.45 10.8 0.6 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 GAO85435.1 - 1.5 9.0 7.1 1.1 9.4 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.17 GAO85437.1 - 2.2e-23 81.6 0.1 2.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85437.1 - 1.7e-17 63.1 0.0 2.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85437.1 - 5.1e-12 45.4 0.0 6.9e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 GAO85437.1 - 0.038 14.4 11.2 0.05 14.0 7.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_3 PF08777.6 GAO85437.1 - 0.044 13.6 0.1 0.072 12.9 0.1 1.3 1 1 0 1 1 1 0 RNA binding motif DUF4078 PF13300.1 GAO85437.1 - 0.072 13.2 0.5 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) ChaC PF04752.7 GAO85439.1 - 1.7e-39 135.6 0.5 3.3e-31 108.6 0.0 2.1 2 0 0 2 2 2 2 ChaC-like protein adh_short PF00106.20 GAO85440.1 - 1.6e-16 60.7 0.0 3.3e-16 59.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO85440.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 KR domain URO-D PF01208.12 GAO85440.1 - 0.048 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) EF-hand_1 PF00036.27 GAO85441.1 - 1.4e-21 74.0 5.4 1.1e-07 30.6 0.1 4.6 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAO85441.1 - 7.6e-20 70.8 1.0 1.1e-09 38.2 1.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAO85441.1 - 9e-19 65.6 2.7 9.7e-06 25.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAO85441.1 - 1e-17 63.4 1.3 1.2e-06 27.9 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 GAO85441.1 - 2.4e-15 55.0 4.2 5.1e-05 22.4 0.4 4.1 4 1 0 4 4 4 3 EF hand MFS_1 PF07690.11 GAO85442.1 - 8.9e-47 159.4 60.4 1.4e-46 158.8 39.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO85442.1 - 1.5e-17 63.0 17.5 1.5e-17 63.0 12.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO85442.1 - 6.9e-16 57.8 11.0 6.9e-16 57.8 7.6 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter SRF-TF PF00319.13 GAO85443.1 - 4e-23 80.3 0.1 6.8e-23 79.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 GAO85444.1 - 6.8e-151 502.8 0.0 2.7e-149 497.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) DJ-1_PfpI PF01965.19 GAO85445.1 - 5.9e-19 67.9 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAO85445.1 - 0.00042 19.7 0.5 0.0021 17.5 0.3 2.1 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family MelC1 PF06236.6 GAO85445.1 - 0.017 15.1 0.4 0.024 14.6 0.3 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 G6PD_C PF02781.11 GAO85446.1 - 5.2e-136 452.2 0.0 7.2e-136 451.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 GAO85446.1 - 5.2e-65 219.1 0.0 9.1e-65 218.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.1 GAO85446.1 - 2.1e-12 46.1 13.7 4.7e-12 45.0 9.5 1.5 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 GAO85446.1 - 0.026 14.2 1.7 0.29 10.9 0.0 3.0 2 0 0 2 2 2 0 MFS_1 like family Ribosomal_L35Ae PF01247.13 GAO85447.1 - 2.4e-43 145.8 0.4 2.7e-43 145.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAO85447.1 - 0.0053 16.6 0.1 2.2 8.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 GAO85448.1 - 4.4e-20 71.9 0.0 1.2e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.3 GAO85449.1 - 2.6e-18 66.1 13.0 1.9e-16 60.1 2.3 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mito_carr PF00153.22 GAO85450.1 - 4.8e-45 151.1 7.4 7.1e-17 60.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 GAO85451.1 - 2.8e-07 30.2 0.0 0.015 15.0 0.0 3.2 2 1 0 2 2 2 2 CBS domain VMA21 PF09446.5 GAO85452.1 - 2.5e-20 72.1 6.5 3.3e-20 71.7 4.5 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 GAO85453.1 - 4.5e-61 206.2 0.2 6.7e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO85453.1 - 1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO85453.1 - 6.7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAO85453.1 - 1.6e-06 27.6 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 GAO85453.1 - 0.024 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Dus PF01207.12 GAO85454.1 - 1.5e-46 158.7 0.0 6.5e-46 156.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PrmA PF06325.8 GAO85454.1 - 0.12 11.5 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Pyrophosphatase PF00719.14 GAO85455.1 - 4.8e-52 175.5 0.1 6.1e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 GAO85456.1 - 7.3e-21 73.8 0.1 1e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 GAO85457.1 - 5.4e-18 64.4 0.9 2.1e-17 62.5 0.7 2.0 1 0 0 1 1 1 1 Sec20 BOF PF04076.8 GAO85457.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein DUF4602 PF15375.1 GAO85457.1 - 1.4 8.9 12.5 0.072 13.1 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) DUF1746 PF08508.5 GAO85458.1 - 3.5e-44 149.4 1.9 5.3e-44 148.8 1.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 GAO85459.1 - 7e-76 253.9 0.0 8.7e-76 253.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease Hydrolase_6 PF13344.1 GAO85461.1 - 2.5e-27 94.7 0.8 1.1e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO85461.1 - 2.2e-12 46.4 0.0 1.2e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO85461.1 - 9.6e-10 39.2 0.1 0.00076 19.9 0.0 2.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAO85461.1 - 1.1e-07 32.2 0.0 5.8e-06 26.6 0.0 2.8 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 GAO85461.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 GAO85461.1 - 0.017 15.3 0.0 0.08 13.1 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 GAO85461.1 - 0.046 13.1 0.0 8.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase AAA PF00004.24 GAO85462.1 - 5.1e-15 55.8 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAO85462.1 - 5.9e-14 52.0 0.0 5.3e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 GAO85462.1 - 4.6e-11 42.1 0.0 1.5e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 GAO85462.1 - 1e-10 41.4 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 GAO85462.1 - 1.9e-06 27.0 0.0 4.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAO85462.1 - 2.4e-05 24.4 0.0 0.00054 20.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO85462.1 - 4.9e-05 22.9 0.0 0.00022 20.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAO85462.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO85462.1 - 8.1e-05 22.6 0.1 0.002 18.1 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 GAO85462.1 - 0.00014 21.0 0.0 0.009 15.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 GAO85462.1 - 0.00014 21.4 0.0 0.0004 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAO85462.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 GAO85462.1 - 0.0014 18.2 0.6 0.0044 16.6 0.2 2.0 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.8 GAO85462.1 - 0.0033 16.9 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 GAO85462.1 - 0.0058 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_5 PF07728.9 GAO85462.1 - 0.0061 16.2 0.1 0.1 12.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAO85462.1 - 0.011 15.1 0.0 0.037 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAO85462.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 GAO85462.1 - 0.046 13.1 0.1 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 GAO85462.1 - 0.05 13.9 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAO85462.1 - 0.057 14.2 0.1 0.16 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAO85462.1 - 0.059 12.9 0.0 0.31 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAO85462.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAO85462.1 - 0.066 12.8 0.0 0.88 9.1 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAO85462.1 - 0.07 13.4 0.0 0.23 11.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 GAO85462.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain FluMu_gp41 PF10109.4 GAO85462.1 - 0.077 12.9 0.1 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 SNF2_N PF00176.18 GAO85462.1 - 0.089 11.5 0.0 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain MCM PF00493.18 GAO85462.1 - 0.094 11.4 0.0 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 MCM2/3/5 family PhoH PF02562.11 GAO85462.1 - 0.1 11.8 0.2 5 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Peptidase_M18 PF02127.10 GAO85463.1 - 3.9e-162 539.6 0.0 4.4e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 GAO85464.1 - 8.2e-37 123.7 6.5 4.3e-08 32.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAO85464.1 - 1.2e-07 31.6 0.2 0.00023 20.9 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 GAO85464.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp E3_binding PF02817.12 GAO85465.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain SMC_N PF02463.14 GAO85466.1 - 2.3e-58 197.0 3.8 5.5e-57 192.5 2.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAO85466.1 - 2.4e-31 108.2 0.0 9.2e-31 106.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAO85466.1 - 1.1e-12 48.5 10.9 7.2e-08 32.7 0.1 3.5 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAO85466.1 - 4.8e-08 32.4 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAO85466.1 - 0.0018 18.1 0.0 0.0087 15.9 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 GAO85466.1 - 0.0019 17.4 19.6 0.7 9.0 1.3 4.4 2 2 2 4 4 4 2 Reovirus sigma C capsid protein IncA PF04156.9 GAO85466.1 - 0.0021 17.6 11.4 0.0021 17.6 7.9 7.2 3 2 4 7 7 5 2 IncA protein TPR_MLP1_2 PF07926.7 GAO85466.1 - 0.025 14.2 0.2 0.025 14.2 0.1 7.3 4 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.1 GAO85466.1 - 0.38 11.0 110.0 5.8 7.1 2.9 6.3 2 2 1 3 3 2 0 AAA domain KxDL PF10241.4 GAO85466.1 - 0.44 10.4 36.6 0.063 13.1 4.5 6.4 5 2 1 6 6 6 0 Uncharacterized conserved protein CcmD PF04995.9 GAO85466.1 - 4.5 7.0 7.1 0.55 9.9 0.8 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2841 PF11001.3 GAO85467.1 - 2.8e-43 146.7 0.2 4.3e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.3 GAO85469.1 - 2e-46 156.4 10.2 2e-46 156.4 7.0 2.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 GAO85469.1 - 0.0092 14.9 3.4 0.014 14.3 2.3 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MtrB PF05440.7 GAO85469.1 - 0.09 12.8 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B OmpH PF03938.9 GAO85469.1 - 0.61 10.0 3.7 0.49 10.3 1.4 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LETM1 PF07766.8 GAO85470.1 - 4e-104 347.4 0.2 4e-104 347.4 0.1 1.5 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 GAO85470.1 - 2e-06 27.1 0.0 0.0049 16.3 0.0 3.6 4 0 0 4 4 4 2 SAP domain NUDIX PF00293.23 GAO85471.1 - 0.0015 18.1 0.5 0.011 15.3 0.3 2.1 1 1 0 1 1 1 1 NUDIX domain Glyco_hydro_38 PF01074.17 GAO85473.1 - 2e-91 306.0 1.8 3.8e-91 305.1 1.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAO85473.1 - 1.2e-75 255.0 0.0 9.2e-75 252.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAO85473.1 - 7.6e-27 93.3 0.0 1.6e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NuA4 PF09340.5 GAO85474.1 - 1.1e-28 98.6 1.2 1.2e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Dehydrin PF00257.14 GAO85474.1 - 0.0069 16.7 7.8 1.7 8.9 5.4 2.4 1 1 0 1 1 1 1 Dehydrin PPP4R2 PF09184.6 GAO85474.1 - 1.2 8.6 5.3 0.2 11.1 0.9 1.6 2 0 0 2 2 2 0 PPP4R2 SR-25 PF10500.4 GAO85474.1 - 4.4 6.7 12.8 8.4 5.7 8.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ctr PF04145.10 GAO85475.1 - 1.8e-37 128.6 1.1 2.5e-37 128.1 0.8 1.2 1 0 0 1 1 1 1 Ctr copper transporter family EpuA PF11772.3 GAO85475.1 - 0.11 12.0 0.4 0.11 12.0 0.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Head-tail_con PF12236.3 GAO85475.1 - 0.13 10.5 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein PRA1 PF03208.14 GAO85475.1 - 6.8 6.0 7.9 14 4.9 2.7 2.1 2 0 0 2 2 2 0 PRA1 family protein Cupin_8 PF13621.1 GAO85476.1 - 1.8e-16 60.4 0.0 6.1e-15 55.4 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAO85476.1 - 9.8e-10 38.6 0.1 1.5e-08 34.9 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 GAO85476.1 - 2.6e-07 30.2 0.1 5.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO85476.1 - 1.3e-05 24.6 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 GAO85476.1 - 0.004 16.4 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein DEAD PF00270.24 GAO85477.1 - 1.2e-43 148.5 1.5 1.9e-43 147.8 0.6 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO85477.1 - 9.3e-28 95.9 0.4 4.2e-27 93.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO85477.1 - 0.0003 20.6 0.0 0.00091 19.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAO85477.1 - 0.00042 19.9 0.1 0.0012 18.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO85477.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain CMS1 PF14617.1 GAO85477.1 - 0.0043 16.1 0.0 0.0091 15.0 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 GAO85477.1 - 0.0078 16.3 0.1 0.03 14.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 GAO85477.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Fanconi_A PF03511.9 GAO85477.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Syntaxin PF00804.20 GAO85478.1 - 7.6e-05 22.8 1.8 0.00017 21.6 1.2 1.5 1 0 0 1 1 1 1 Syntaxin IncA PF04156.9 GAO85478.1 - 0.00045 19.8 2.9 0.00085 18.9 2.0 1.3 1 0 0 1 1 1 1 IncA protein Baculo_PEP_C PF04513.7 GAO85478.1 - 0.0015 18.3 0.3 0.0027 17.5 0.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 GAO85478.1 - 0.0084 15.6 2.5 0.012 15.1 0.9 1.8 2 0 0 2 2 2 1 Intermediate filament protein Retrotrans_gag PF03732.12 GAO85478.1 - 0.0087 16.1 0.0 0.21 11.6 0.0 2.6 3 0 0 3 3 2 1 Retrotransposon gag protein TBPIP PF07106.8 GAO85478.1 - 0.013 15.0 0.7 0.026 14.0 0.5 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 GAO85478.1 - 0.033 13.9 0.4 0.19 11.4 0.3 2.2 1 1 0 1 1 1 0 Prefoldin subunit Spc24 PF08286.6 GAO85478.1 - 0.061 13.0 2.6 0.35 10.5 0.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Transposase_22 PF02994.9 GAO85478.1 - 0.07 11.6 1.7 0.12 10.8 1.2 1.3 1 0 0 1 1 1 0 L1 transposable element Mod_r PF07200.8 GAO85478.1 - 0.078 12.8 1.3 0.99 9.3 0.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF904 PF06005.7 GAO85478.1 - 0.078 13.2 0.6 0.18 12.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 GAO85478.1 - 0.088 12.5 1.0 0.26 11.0 0.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 GAO85478.1 - 0.096 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Uds1 PF15456.1 GAO85478.1 - 0.098 12.6 1.5 0.22 11.4 1.1 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Cep57_CLD_2 PF14197.1 GAO85478.1 - 0.15 12.0 5.1 1.7 8.6 0.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Lge1 PF11488.3 GAO85478.1 - 0.28 11.4 1.6 1.3 9.2 0.6 2.5 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 FAA_hydrolase PF01557.13 GAO85479.1 - 5.3e-50 169.8 0.0 6.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PWI PF01480.12 GAO85480.1 - 1.3e-29 102.1 0.1 2.2e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.20 GAO85482.1 - 2.2e-47 161.4 0.0 3.1e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85482.1 - 8.4e-17 61.0 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAO85482.1 - 0.00028 20.2 0.2 0.00047 19.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 GAO85482.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO85482.1 - 0.034 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 GAO85482.1 - 0.2 9.7 0.0 0.3 9.1 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S8e PF01201.17 GAO85483.1 - 7.6e-35 119.9 6.3 2.4e-34 118.3 4.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 GAO85483.1 - 1.3 9.2 8.4 2.5 8.3 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) RIB43A PF05914.7 GAO85484.1 - 0.00011 20.9 0.7 0.00015 20.5 0.5 1.1 1 0 0 1 1 1 1 RIB43A Pol_alpha_B_N PF08418.5 GAO85484.1 - 0.06 12.8 5.2 0.096 12.2 3.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GMC_oxred_N PF00732.14 GAO85485.1 - 2.6e-52 177.8 0.0 3.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO85485.1 - 8e-37 126.7 0.0 1.6e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO85485.1 - 1.7e-06 27.1 0.5 0.0011 17.9 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO85485.1 - 7.6e-06 25.0 0.0 3.2e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO85485.1 - 0.00035 20.5 0.4 0.0013 18.7 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO85485.1 - 0.0018 17.4 0.1 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAO85485.1 - 0.0018 17.2 0.1 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAO85485.1 - 0.0044 16.9 0.3 0.0087 15.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO85485.1 - 0.0051 16.8 0.5 0.46 10.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO85485.1 - 0.012 14.3 0.1 0.016 13.8 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAO85485.1 - 0.015 15.0 0.9 0.048 13.4 0.1 2.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO85485.1 - 0.077 11.4 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 GAO85485.1 - 0.46 10.9 2.8 0.24 11.8 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1338 PF07063.8 GAO85486.1 - 3.5e-94 315.2 0.2 4.2e-94 314.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.13 GAO85487.1 - 3.6e-20 71.9 0.1 8.7e-20 70.6 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85487.1 - 0.0015 18.3 7.0 0.0028 17.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Met_10 PF02475.11 GAO85488.1 - 2.3e-68 229.7 0.0 3.4e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 GAO85488.1 - 7.7e-26 90.3 3.3 1.5e-25 89.4 2.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb4 MethyltransfD12 PF02086.10 GAO85488.1 - 0.027 13.9 0.5 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 GAO85488.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase zf-GRF PF06839.7 GAO85489.1 - 3.9e-08 33.1 6.4 7.7e-08 32.1 4.5 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF3818 PF12825.2 GAO85490.1 - 5e-140 466.0 1.8 7.3e-140 465.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAO85490.1 - 8.1e-43 145.3 0.5 1.9e-42 144.1 0.3 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 GAO85490.1 - 6.6e-14 51.6 1.0 1.5e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 PX domain zf-C2H2 PF00096.21 GAO85491.1 - 0.00019 21.5 3.9 0.00019 21.5 2.7 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO85491.1 - 0.083 13.2 16.6 0.039 14.2 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger AAA PF00004.24 GAO85492.1 - 2.5e-48 163.6 0.0 3.7e-43 146.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAO85492.1 - 5.9e-05 22.5 0.0 0.00023 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO85492.1 - 7.3e-05 23.5 0.0 0.0013 19.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAO85492.1 - 0.00014 21.0 0.0 0.00041 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 GAO85492.1 - 0.00047 19.1 0.0 0.00079 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 GAO85492.1 - 0.0008 19.4 0.7 0.025 14.5 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO85492.1 - 0.00083 19.5 0.0 0.0066 16.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAO85492.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 GAO85492.1 - 0.0031 17.4 0.0 0.0077 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 GAO85492.1 - 0.0034 17.5 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 GAO85492.1 - 0.0048 16.6 1.1 0.027 14.1 0.0 2.8 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 GAO85492.1 - 0.0056 15.4 0.0 0.0091 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 GAO85492.1 - 0.019 15.2 0.0 0.094 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAO85492.1 - 0.022 13.9 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO85492.1 - 0.023 14.4 0.0 0.074 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 GAO85492.1 - 0.028 13.5 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 GAO85492.1 - 0.036 13.3 0.0 0.084 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 GAO85492.1 - 0.073 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAO85492.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAO85492.1 - 0.13 11.6 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 GAO85492.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 GAO85492.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AA_permease_2 PF13520.1 GAO85493.1 - 6.5e-53 179.7 53.0 8.1e-53 179.4 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO85493.1 - 8.5e-16 57.3 44.3 1.4e-15 56.6 30.7 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3368 PF11848.3 GAO85493.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) DUF4243 PF14027.1 GAO85494.1 - 6.3e-95 318.3 6.8 7.6e-95 318.1 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 GAO85495.1 - 3.2e-98 328.7 0.0 2.4e-97 325.8 0.0 1.9 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TauD PF02668.11 GAO85496.1 - 1.2e-54 185.6 0.6 1.5e-54 185.3 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAO85497.1 - 3.2e-25 88.6 21.2 4.6e-25 88.0 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO85497.1 - 0.0072 16.0 0.7 0.0072 16.0 0.5 2.1 2 0 0 2 2 2 1 MFS_1 like family PI-PLC-X PF00388.14 GAO85498.1 - 1.7e-61 205.9 0.0 2.5e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAO85498.1 - 4.9e-37 126.5 0.0 9e-37 125.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 GAO85498.1 - 0.033 14.0 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 C2 domain GST_N_3 PF13417.1 GAO85499.1 - 8e-10 38.8 0.1 1.5e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO85499.1 - 6.4e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO85499.1 - 6.2e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO85499.1 - 2.3e-05 24.7 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO85499.1 - 0.00072 19.5 0.1 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L37 PF08561.5 GAO85500.1 - 2e-31 107.4 4.7 1.3e-30 104.7 3.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Epimerase PF01370.16 GAO85501.1 - 1.7e-35 122.5 0.0 6.1e-35 120.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAO85501.1 - 1.1e-11 44.4 0.1 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 GAO85501.1 - 2.2e-09 36.6 0.0 9.2e-08 31.3 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAO85501.1 - 1.5e-08 33.8 0.0 2.7e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAO85501.1 - 2.4e-06 26.4 0.0 2.7e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO85501.1 - 1.5e-05 24.9 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO85501.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAO85501.1 - 6.5e-05 21.9 0.0 0.0012 17.8 0.0 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAO85501.1 - 0.033 14.2 0.1 0.98 9.3 0.0 3.0 2 1 1 3 3 3 0 NADH(P)-binding Spherulin4 PF12138.3 GAO85502.1 - 2e-73 246.9 0.0 2.3e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glyco_hydro_114 PF03537.8 GAO85503.1 - 1.9e-26 91.6 0.2 3.4e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.16 GAO85504.1 - 0.074 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide deacetylase Glycos_transf_1 PF00534.15 GAO85505.1 - 2.7e-12 46.4 0.0 6.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO85505.1 - 4e-05 23.7 0.0 0.00062 19.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 DUF3492 PF11997.3 GAO85505.1 - 5.7e-05 22.7 0.0 0.0004 20.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) DPPIV_N PF00930.16 GAO85506.1 - 5.8e-112 373.7 0.2 7.7e-112 373.3 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAO85506.1 - 3.3e-54 183.3 2.9 6.7e-54 182.3 2.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO85506.1 - 4.5e-08 32.9 0.0 1.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAO85506.1 - 0.0012 18.3 3.5 0.0029 17.0 2.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Neurensin PF14927.1 GAO85506.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Neurensin PAF-AH_p_II PF03403.8 GAO85506.1 - 0.026 12.8 0.0 2.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 GAO85506.1 - 0.054 12.7 0.0 0.31 10.3 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Kelch_3 PF13415.1 GAO85506.1 - 0.061 13.5 0.3 2.2 8.5 0.0 3.5 2 0 0 2 2 2 0 Galactose oxidase, central domain CHB_HEX PF03173.8 GAO85506.1 - 0.1 12.0 0.1 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain Cpn60_TCP1 PF00118.19 GAO85508.1 - 3.1e-138 461.4 8.4 3.8e-138 461.1 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 GAO85508.1 - 0.026 13.9 0.0 0.07 12.6 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X GTP1_OBG PF01018.17 GAO85508.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 GTP1/OBG AAA PF00004.24 GAO85509.1 - 1.2e-40 138.7 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO85509.1 - 4.9e-06 26.7 0.0 0.0006 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 GAO85509.1 - 5.6e-05 22.8 0.1 0.0003 20.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO85509.1 - 0.00024 21.1 0.1 0.0015 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 GAO85509.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAO85509.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAO85509.1 - 0.0039 17.9 0.1 0.012 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAO85509.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAO85509.1 - 0.01 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAO85509.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAO85509.1 - 0.019 14.9 0.1 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO85509.1 - 0.034 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAO85509.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 GAO85509.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAO85509.1 - 0.065 12.8 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAO85509.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 GAO85509.1 - 0.095 13.0 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 GAO85509.1 - 0.098 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAO85509.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FAD_binding_2 PF00890.19 GAO85510.1 - 8.3e-127 423.4 3.5 1e-126 423.1 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAO85510.1 - 4.3e-47 159.1 1.3 6.2e-47 158.6 0.9 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 GAO85510.1 - 6e-08 32.8 0.0 0.0032 17.3 0.6 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO85510.1 - 8.4e-06 25.0 0.4 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 GAO85510.1 - 5.2e-05 22.2 1.7 0.038 12.8 1.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 GAO85510.1 - 6.4e-05 22.0 0.2 0.001 18.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO85510.1 - 0.0062 15.6 0.9 0.0098 14.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAO85510.1 - 0.11 10.9 1.1 0.46 8.9 0.2 2.3 3 0 0 3 3 3 0 HI0933-like protein Mucin PF01456.12 GAO85511.1 - 0.00028 20.6 17.0 0.00028 20.6 11.7 2.4 2 1 0 2 2 2 1 Mucin-like glycoprotein DUF1191 PF06697.7 GAO85511.1 - 0.0034 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 GAO85511.1 - 0.0055 16.3 0.1 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain MGC-24 PF05283.6 GAO85511.1 - 0.0059 16.4 10.6 0.0059 16.4 7.3 2.4 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) Lyase_1 PF00206.15 GAO85512.1 - 1.8e-88 296.7 0.0 2.8e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 GAO85512.1 - 3.4e-26 91.0 0.1 8.9e-26 89.7 0.1 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Membralin PF09746.4 GAO85512.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein TPR_10 PF13374.1 GAO85513.1 - 3.5e-48 160.2 0.2 9.5e-10 38.0 0.1 6.3 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85513.1 - 7.1e-41 138.0 2.2 5.4e-12 45.4 0.1 4.9 2 1 4 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 GAO85513.1 - 4.8e-13 48.5 0.0 8.1e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 GAO85513.1 - 6.9e-10 38.2 0.0 1.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 GAO85513.1 - 2.6e-07 30.8 0.0 1.1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO85513.1 - 1.6e-06 28.2 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.1 GAO85513.1 - 2.6e-05 23.6 5.5 5.8 6.9 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.7 GAO85513.1 - 3.6e-05 23.4 0.0 7.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 GAO85513.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase TPR_17 PF13431.1 GAO85513.1 - 0.0035 17.4 0.0 45 4.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TrwB_AAD_bind PF10412.4 GAO85513.1 - 0.0043 15.7 0.0 0.012 14.2 0.0 1.7 1 1 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 GAO85513.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_16 PF13432.1 GAO85513.1 - 0.039 14.6 0.1 0.039 14.6 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1924 PF09086.6 GAO85513.1 - 0.04 13.9 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1924) AAA_31 PF13614.1 GAO85513.1 - 0.076 12.9 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO85513.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAO85513.1 - 0.14 12.9 0.3 0.64 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain TPR_2 PF07719.12 GAO85513.1 - 3.8 7.6 12.3 9.1 6.4 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat FR47 PF08445.5 GAO85514.1 - 1.6e-07 30.9 0.1 1e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAO85514.1 - 1.2e-06 28.7 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO85514.1 - 4.4e-06 26.6 0.1 9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO85514.1 - 0.00075 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO85514.1 - 0.044 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 GAO85514.1 - 0.05 13.7 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FDX-ACB PF03147.9 GAO85516.1 - 0.086 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain RRM_1 PF00076.17 GAO85518.1 - 5.5e-43 144.4 0.0 1.8e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85518.1 - 1.7e-37 127.2 0.0 1.9e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85518.1 - 8.7e-20 70.3 0.0 5.8e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 GAO85519.1 - 1.5e-132 442.7 21.0 1.6e-84 284.4 6.7 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 GAO85520.1 - 3e-21 75.1 6.3 4.1e-21 74.7 4.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 GAO85520.1 - 0.0087 15.8 1.8 0.48 10.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 GAO85521.1 - 4.9e-11 41.5 1.4 0.04 13.9 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 GAO85521.1 - 5.1e-09 35.5 1.0 0.075 12.6 0.0 5.5 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAO85521.1 - 1.1e-05 24.8 1.0 16 6.0 0.0 6.5 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 GAO85521.1 - 0.015 15.3 1.8 2.5e+02 2.6 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat LRR_8 PF13855.1 GAO85521.1 - 0.018 14.7 5.8 1.4 8.7 0.0 5.0 5 2 0 5 5 5 0 Leucine rich repeat Mpp10 PF04006.7 GAO85521.1 - 0.079 11.3 15.9 0.1 10.9 11.0 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIS_M PF07500.9 GAO85522.1 - 2.4e-28 98.5 1.6 2.4e-28 98.5 1.1 2.4 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 GAO85522.1 - 1e-18 66.6 5.9 1.7e-18 65.9 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 GAO85522.1 - 1.1e-13 50.4 0.6 2.8e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 GAO85522.1 - 0.011 15.1 1.5 0.03 13.7 1.0 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Chordopox_A33R PF05966.7 GAO85522.1 - 0.11 11.3 2.6 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein E7 PF00527.13 GAO85522.1 - 3.3 7.9 6.7 23 5.2 4.6 2.3 1 1 0 1 1 1 0 E7 protein, Early protein Microtub_bind PF13931.1 GAO85522.1 - 7.2 6.7 10.2 5.2 7.2 1.9 2.9 2 1 1 3 3 3 0 Kinesin-associated microtubule-binding Pectinesterase PF01095.14 GAO85524.1 - 1.5e-27 96.0 5.0 2.7e-22 78.6 1.1 2.1 2 0 0 2 2 2 2 Pectinesterase E1-E2_ATPase PF00122.15 GAO85525.1 - 8.3e-69 231.1 1.9 8.3e-69 231.1 1.3 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 GAO85525.1 - 2.4e-23 83.6 0.9 5.9e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO85525.1 - 4.5e-13 49.7 0.0 1.4e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO85525.1 - 6e-10 38.4 0.0 1.8e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAO85525.1 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO85525.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 GAO85525.1 - 0.092 12.6 0.1 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif Lactamase_B PF00753.22 GAO85526.1 - 9.8e-09 35.1 0.5 1.9e-07 30.9 0.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO85526.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CYTL1 PF15153.1 GAO85527.1 - 0.083 12.5 0.0 0.93 9.1 0.0 2.0 2 0 0 2 2 2 0 Cytokine-like protein 1 ABC1 PF03109.11 GAO85528.1 - 2.6e-20 72.5 0.0 6.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 GAO85528.1 - 0.0089 15.7 1.3 0.053 13.2 0.2 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family SNARE PF05739.14 GAO85531.1 - 1.5e-17 62.9 0.7 1.5e-17 62.9 0.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAO85531.1 - 5e-16 58.7 3.0 1.8e-15 56.9 0.3 2.6 2 0 0 2 2 2 1 Syntaxin zf-C4H2 PF10146.4 GAO85531.1 - 0.0041 17.1 0.2 0.3 11.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger-containing protein Sed5p PF11416.3 GAO85531.1 - 0.0065 15.8 0.1 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Integral membrane protein Sed5p MCPsignal PF00015.16 GAO85531.1 - 0.0093 15.5 0.7 0.0093 15.5 0.5 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 GAO85531.1 - 0.019 15.2 3.9 3.2 8.0 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 GAO85531.1 - 0.091 12.6 1.8 6.4 6.7 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein MerR-DNA-bind PF09278.6 GAO85531.1 - 2.9 8.3 6.6 2.5 8.5 0.7 3.4 3 1 1 4 4 4 0 MerR, DNA binding Peptidase_M50B PF13398.1 GAO85532.1 - 2.3e-55 187.1 21.8 3.3e-55 186.5 15.1 1.2 1 0 0 1 1 1 1 Peptidase M50B-like ECH PF00378.15 GAO85532.1 - 2.7e-36 124.9 0.6 7.6e-23 80.8 0.7 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_M50 PF02163.17 GAO85532.1 - 0.03 13.3 3.3 0.12 11.2 2.3 2.2 1 1 0 1 1 1 0 Peptidase family M50 Patched PF02460.13 GAO85532.1 - 3.7 5.3 6.4 5.4 4.8 4.5 1.1 1 0 0 1 1 1 0 Patched family DUF1275 PF06912.6 GAO85533.1 - 1.2e-40 138.9 12.4 1.6e-40 138.5 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YwiC PF14256.1 GAO85533.1 - 1.6 8.8 11.9 0.19 11.7 0.8 2.3 2 0 0 2 2 2 0 YwiC-like protein Ion_trans_2 PF07885.11 GAO85534.1 - 5.2e-24 83.7 24.2 9.5e-14 50.8 5.9 3.1 3 1 0 3 3 3 2 Ion channel Anp1 PF03452.9 GAO85534.1 - 0.11 11.6 0.2 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Anp1 SUR7 PF06687.7 GAO85535.1 - 2.2e-28 99.2 12.1 2.8e-28 98.9 8.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family 2TM PF13239.1 GAO85535.1 - 0.1 12.6 0.3 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 2TM domain CoA_binding_3 PF13727.1 GAO85535.1 - 0.31 10.8 1.1 0.59 9.9 0.8 1.5 1 0 0 1 1 1 0 CoA-binding domain DUF4231 PF14015.1 GAO85535.1 - 6.4 6.8 5.7 1.2 9.1 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Pectate_lyase_3 PF12708.2 GAO85536.1 - 1.2e-55 189.0 26.8 7.1e-44 150.5 6.1 3.3 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAO85536.1 - 0.087 12.3 0.5 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF3433 PF11915.3 GAO85537.1 - 3.8e-39 132.7 19.1 8.1e-29 99.6 1.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) CD20 PF04103.10 GAO85538.1 - 0.12 12.3 0.0 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 CD20-like family RRM_1 PF00076.17 GAO85539.1 - 2e-12 46.5 0.3 5.9e-05 22.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 GAO85539.1 - 1.1e-11 44.2 0.8 2.1e-11 43.4 0.6 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 GAO85539.1 - 9.3e-10 37.4 2.8 1.7e-09 36.5 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 GAO85539.1 - 1.6e-09 37.5 0.1 0.0026 17.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 GAO85539.1 - 2.2e-06 27.3 0.3 2.2e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 GAO85539.1 - 0.0028 17.4 0.0 0.0082 15.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NACHT PF05729.7 GAO85540.1 - 2e-06 27.5 0.1 6.4e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 NACHT domain WD40 PF00400.27 GAO85540.1 - 3.2e-05 23.6 0.5 26 4.9 0.0 5.6 4 1 0 4 4 4 2 WD domain, G-beta repeat AAA_22 PF13401.1 GAO85540.1 - 0.0033 17.5 1.6 0.16 12.1 0.0 3.8 4 1 1 5 5 5 1 AAA domain RNA_helicase PF00910.17 GAO85540.1 - 0.02 15.0 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Fructosamin_kin PF03881.9 GAO85541.1 - 5e-42 143.8 0.0 6.8e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase dCMP_cyt_deam_1 PF00383.17 GAO85541.1 - 1.8e-14 53.1 0.0 3.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APH PF01636.18 GAO85541.1 - 0.00015 21.5 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pro_isomerase PF00160.16 GAO85542.1 - 1.7e-46 158.2 0.6 1.9e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1622 PF07784.6 GAO85543.1 - 0.073 12.7 1.3 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) DUF2921 PF11145.3 GAO85543.1 - 0.097 10.3 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) MtrD PF04207.7 GAO85543.1 - 0.63 9.3 5.1 0.71 9.2 0.5 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D FAD_binding_4 PF01565.18 GAO85544.1 - 1.3e-17 63.6 2.0 1.3e-17 63.5 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO85544.1 - 7.2e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Corona_NS2 PF04753.7 GAO85545.1 - 4.4 7.2 30.8 25 4.8 0.1 7.0 6 1 1 7 7 7 0 Coronavirus non-structural protein NS2 VARLMGL PF14383.1 GAO85545.1 - 7.2 5.8 15.8 49 3.2 0.1 6.4 7 0 0 7 7 7 0 DUF761-associated sequence motif Alpha-amylase PF00128.19 GAO85547.1 - 3.3e-98 328.9 3.6 3.3e-98 328.9 2.5 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAO85547.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 GAO85547.1 - 0.038 14.1 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain MoaE PF02391.12 GAO85548.1 - 4.9e-32 110.1 0.0 6.1e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 GAO85549.1 - 1.2e-58 197.5 0.0 1.6e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 GAO85549.1 - 3.5e-05 23.4 0.1 7e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 GAO85549.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAO85549.1 - 0.13 11.8 0.0 0.38 10.2 0.0 1.8 1 1 0 1 1 1 0 Redoxin CAF-1_p150 PF11600.3 GAO85550.1 - 1 8.7 30.6 0.22 10.8 0.7 2.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Yae1_N PF09811.4 GAO85552.1 - 2.3e-12 46.2 0.3 5.1e-12 45.0 0.2 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ABM PF03992.11 GAO85552.1 - 0.018 15.0 1.2 0.037 14.0 0.8 1.6 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Romo1 PF10247.4 GAO85552.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 ABC2_membrane PF01061.19 GAO85554.1 - 2.2e-88 294.8 55.4 5.2e-47 159.7 16.2 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 GAO85554.1 - 1.6e-36 125.6 0.0 6.2e-18 65.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO85554.1 - 1e-35 121.4 2.4 9.2e-32 108.7 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 GAO85554.1 - 9.2e-18 64.1 0.0 2.6e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO85554.1 - 4.3e-09 36.0 0.0 1.7e-05 24.3 0.0 2.6 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAO85554.1 - 1.4e-07 30.9 17.4 1.4e-07 30.9 12.1 3.2 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.1 GAO85554.1 - 1.1e-05 25.3 0.1 0.0099 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO85554.1 - 1.6e-05 24.9 0.3 0.00061 19.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAO85554.1 - 6.9e-05 22.0 0.0 0.0058 15.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 GAO85554.1 - 0.00033 19.6 10.8 0.00033 19.6 7.5 2.8 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_18 PF13238.1 GAO85554.1 - 0.00052 20.3 0.0 0.072 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAO85554.1 - 0.00099 19.9 0.0 0.53 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAO85554.1 - 0.0023 17.4 1.4 0.036 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAO85554.1 - 0.0028 17.7 0.2 0.67 10.1 0.1 3.4 3 1 0 3 3 3 1 AAA domain cobW PF02492.14 GAO85554.1 - 0.003 17.0 0.1 0.003 17.0 0.1 2.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 GAO85554.1 - 0.0039 16.4 0.1 0.076 12.2 0.0 2.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 GAO85554.1 - 0.01 15.4 0.8 2.7 7.6 0.2 3.0 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.1 GAO85554.1 - 0.044 13.5 1.2 3.1 7.6 0.3 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 GAO85554.1 - 0.079 12.9 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAO85554.1 - 0.13 12.1 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 GAO85554.1 - 0.38 10.3 1.4 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MiAMP1 PF09117.5 GAO85555.1 - 0.15 12.5 1.4 2.2 8.7 0.1 2.2 1 1 1 2 2 2 0 MiAMP1 Acatn PF13000.2 GAO85556.1 - 9.7e-148 493.0 21.9 5.9e-76 256.1 6.0 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 SOG2 PF10428.4 GAO85556.1 - 0.12 10.9 3.2 0.18 10.4 2.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CENP-O PF09496.5 GAO85557.1 - 1.7e-31 108.3 0.1 3.8e-31 107.1 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component ZapA PF05164.8 GAO85557.1 - 0.013 15.4 0.9 0.024 14.6 0.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapA DivIVA PF05103.8 GAO85557.1 - 0.016 15.2 0.7 0.024 14.6 0.5 1.2 1 0 0 1 1 1 0 DivIVA protein FUSC PF04632.7 GAO85557.1 - 0.047 12.1 1.8 0.034 12.5 0.2 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Abhydrolase_3 PF07859.8 GAO85559.1 - 2.9e-41 141.3 0.0 3.6e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO85559.1 - 0.00012 21.4 0.0 0.00022 20.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAO85559.1 - 0.00013 21.9 1.8 0.00026 20.9 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85559.1 - 0.00019 21.2 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO85559.1 - 0.0027 16.2 0.0 0.022 13.2 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 GAO85559.1 - 0.0035 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAO85559.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 GAO85559.1 - 0.021 13.5 0.0 0.042 12.5 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family Lipase_3 PF01764.20 GAO85559.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 GAO85559.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 GAO85559.1 - 0.062 12.7 0.0 0.4 10.0 0.0 2.2 2 1 1 3 3 3 0 Putative esterase Peptidase_S15 PF02129.13 GAO85559.1 - 0.074 12.4 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Rootletin PF15035.1 GAO85560.1 - 1.9 8.4 8.7 5 7.0 6.0 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DFP PF04127.10 GAO85561.1 - 3.1e-14 52.9 0.0 4e-05 23.3 0.0 3.2 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Fringe PF02434.11 GAO85562.1 - 2.7e-08 33.3 0.1 3.9e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 GAO85562.1 - 0.004 16.8 0.5 0.0079 15.8 0.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 GAO85562.1 - 0.0063 16.1 0.6 0.012 15.1 0.4 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_2 PF08276.6 GAO85562.1 - 0.027 14.3 0.7 0.054 13.3 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain Polysacc_deac_1 PF01522.16 GAO85563.1 - 3.9e-19 68.4 0.0 7.4e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DEAD PF00270.24 GAO85564.1 - 9.4e-43 145.6 0.0 5.3e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO85564.1 - 1.1e-21 76.4 0.1 3.1e-21 75.0 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO85564.1 - 4.6e-05 22.3 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 GAO85564.1 - 0.019 14.2 0.0 0.16 11.2 0.0 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain ResIII PF04851.10 GAO85564.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Fumble PF03630.9 GAO85565.1 - 1.6e-139 464.4 0.4 1.2e-138 461.6 0.3 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 GAO85566.1 - 2.7e-128 427.2 0.2 3.4e-128 426.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CDC45 PF02724.9 GAO85566.1 - 0.33 8.9 1.8 0.48 8.3 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.23 GAO85567.1 - 4.3e-49 167.7 4.2 1.2e-47 163.0 2.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAO85567.1 - 6.1e-06 26.1 23.1 1.2e-05 25.1 16.0 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.1 GAO85567.1 - 0.018 13.4 0.1 0.033 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 DUF1943 PF09172.6 GAO85568.1 - 0.027 13.3 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FAD_binding_4 PF01565.18 GAO85569.1 - 2.4e-17 62.7 2.2 2.4e-17 62.7 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO85569.1 - 6.2e-08 32.4 0.0 1.5e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldedh PF00171.17 GAO85570.1 - 1.1e-156 521.7 0.5 1.3e-156 521.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 GAO85570.1 - 0.057 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase PTH2 PF01981.11 GAO85570.1 - 0.26 10.9 1.1 1.1 9.0 0.1 2.3 2 1 1 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 Gln-synt_C PF00120.19 GAO85571.1 - 8.7e-45 152.8 0.0 1.8e-44 151.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 GAO85571.1 - 2.6e-34 119.0 0.2 6.8e-34 117.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase GCS2 PF04107.8 GAO85571.1 - 0.047 12.7 0.3 0.78 8.7 0.0 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) HATPase_c PF02518.21 GAO85572.1 - 7.2e-24 83.6 0.1 1.5e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO85572.1 - 4.6e-20 71.7 0.0 1.6e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAO85572.1 - 9.1e-13 47.9 0.2 3.5e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 GAO85572.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 GAF domain MFS_1 PF07690.11 GAO85573.1 - 3.7e-35 121.2 27.9 4.6e-35 120.9 16.2 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 GAO85573.1 - 2.4e-16 60.1 1.5 3.2e-16 59.7 0.3 1.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.19 GAO85573.1 - 9.2e-12 44.2 13.4 9.2e-12 44.2 9.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter UPF0016 PF01169.14 GAO85575.1 - 1.3e-40 137.3 24.8 4.7e-21 74.7 5.4 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 GAO85575.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Myb_DNA-binding PF00249.26 GAO85576.1 - 3.2e-08 33.4 0.1 1.3e-07 31.5 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO85576.1 - 7.1e-05 22.8 0.0 0.00025 21.1 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain WSC PF01822.14 GAO85577.1 - 7.8e-12 44.9 7.2 7.8e-12 44.9 5.0 1.9 2 0 0 2 2 2 1 WSC domain KAR9 PF08580.5 GAO85577.1 - 1.2 7.2 4.1 1.5 7.0 2.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_M20 PF01546.23 GAO85578.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO85578.1 - 4.1e-08 32.9 0.0 8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO85578.1 - 3.7e-05 23.5 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF4431 PF14485.1 GAO85578.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4431) DUF1793 PF08760.6 GAO85579.1 - 5.4e-69 231.4 0.3 1.1e-68 230.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Annexin PF00191.15 GAO85580.1 - 3e-18 65.4 6.7 3e-05 23.8 0.1 4.5 4 0 0 4 4 4 4 Annexin Septin PF00735.13 GAO85581.1 - 4.3e-34 117.8 0.0 4e-14 52.3 0.0 3.1 2 1 1 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 GAO85581.1 - 0.0051 16.3 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 GAO85581.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 GAO85581.1 - 0.059 12.0 0.1 0.16 10.6 0.0 1.8 1 1 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 GAO85581.1 - 0.1 12.4 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.8 GAO85581.1 - 1.2 8.9 7.5 0.15 11.9 0.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF946 PF06101.6 GAO85582.1 - 2.6e-14 52.1 1.3 4e-11 41.6 0.4 2.3 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 GAO85582.1 - 0.011 15.4 1.2 0.016 14.9 0.8 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) BA14K PF07886.6 GAO85582.1 - 0.19 11.4 3.7 0.43 10.2 2.6 1.5 1 0 0 1 1 1 0 BA14K-like protein Baculo_PEP_C PF04513.7 GAO85584.1 - 0.0097 15.7 2.1 0.38 10.5 0.1 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 GAO85584.1 - 0.012 15.9 14.8 0.064 13.6 0.8 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Spc7 PF08317.6 GAO85584.1 - 0.021 13.4 9.3 0.097 11.3 0.6 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 GAO85584.1 - 0.052 13.1 23.6 0.03 13.9 1.6 3.2 1 1 2 3 3 3 0 IncA protein RmuC PF02646.11 GAO85584.1 - 0.058 12.2 9.1 0.056 12.2 1.0 2.4 2 0 0 2 2 2 0 RmuC family ISG65-75 PF11727.3 GAO85584.1 - 0.094 11.7 5.5 0.046 12.7 1.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Reo_sigmaC PF04582.7 GAO85584.1 - 0.11 11.7 2.1 0.41 9.7 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FeoC PF09012.5 GAO85584.1 - 0.16 11.6 1.9 0.45 10.2 0.2 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator Filament PF00038.16 GAO85584.1 - 0.18 11.2 17.8 3.5 6.9 1.5 3.2 3 0 0 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 GAO85584.1 - 0.21 9.9 8.9 0.24 9.8 1.1 1.9 1 1 1 2 2 2 0 AAA domain DUF3552 PF12072.3 GAO85584.1 - 0.25 10.5 14.5 1.5 7.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) BLOC1_2 PF10046.4 GAO85584.1 - 0.27 11.4 8.4 0.11 12.6 0.9 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 GAO85584.1 - 0.36 10.6 7.6 1.2 9.0 0.5 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.1 GAO85584.1 - 0.41 10.9 5.4 3.4 7.9 3.7 2.1 1 1 0 1 1 1 0 AAA domain Mod_r PF07200.8 GAO85584.1 - 0.51 10.2 17.5 0.048 13.5 2.4 3.3 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF947 PF06102.7 GAO85584.1 - 0.6 9.9 9.3 0.83 9.4 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF947) NAM-associated PF14303.1 GAO85584.1 - 0.75 10.0 17.4 0.28 11.5 5.6 2.7 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Med9 PF07544.8 GAO85584.1 - 1.3 8.7 12.7 5.5 6.7 1.2 3.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin PF02996.12 GAO85584.1 - 2.1 8.0 15.3 0.09 12.4 1.3 3.9 2 1 3 5 5 5 0 Prefoldin subunit Cob_adeno_trans PF01923.13 GAO85584.1 - 3.5 7.4 8.0 3.5 7.3 0.7 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase CENP-F_leu_zip PF10473.4 GAO85584.1 - 5.8 6.7 20.8 4.1 7.2 3.2 3.3 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 GAO85584.1 - 8.4 5.9 22.8 2.4 7.7 5.1 4.2 3 1 1 4 4 4 0 Septum formation initiator TBPIP PF07106.8 GAO85584.1 - 9.2 5.7 15.6 0.98 8.9 1.6 3.2 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_S4 PF00163.14 GAO85585.1 - 1.8e-30 105.1 1.0 3e-30 104.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAO85585.1 - 3.2e-13 48.8 0.8 3.2e-13 48.8 0.6 2.2 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 GAO85586.1 - 2e-38 130.1 6.2 2e-38 130.1 4.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Mito_carr PF00153.22 GAO85587.1 - 1.6e-76 252.1 2.6 3.4e-25 87.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 GAO85587.1 - 0.0059 16.0 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) zf-C2H2_4 PF13894.1 GAO85588.1 - 0.63 10.5 17.2 0.13 12.6 0.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger DEAD PF00270.24 GAO85589.1 - 9e-18 64.3 0.0 3e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO85589.1 - 2e-08 34.0 0.0 4.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO85589.1 - 2.1e-07 30.9 0.0 2.1e-07 30.9 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 GAO85589.1 - 0.00085 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein WD40 PF00400.27 GAO85590.1 - 2.7e-25 87.2 18.9 6.2e-08 32.2 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAO85590.1 - 0.00055 18.3 3.5 0.11 10.7 0.0 3.8 4 0 0 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 GAO85590.1 - 0.0039 17.4 0.3 0.54 10.6 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 GAO85590.1 - 0.0095 14.7 0.3 0.23 10.1 0.1 2.7 3 1 0 3 3 3 1 Nup133 N terminal like BBS2_N PF14781.1 GAO85590.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 GAO85590.1 - 0.1 12.3 0.0 22 4.8 0.0 3.7 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 GAO85590.1 - 0.1 12.2 2.1 0.17 11.5 0.0 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SecE PF00584.15 GAO85591.1 - 5.7e-07 29.0 0.0 7.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 GAO85592.1 - 1.9e-08 34.1 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO85592.1 - 1.5e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85592.1 - 0.0006 19.6 0.1 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PX PF00787.19 GAO85593.1 - 4.1e-26 90.9 0.2 8.9e-26 89.9 0.1 1.6 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.1 GAO85594.1 - 5.1e-16 58.5 0.0 3.4e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO85594.1 - 8.3e-12 44.9 0.7 1.1e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_ner PF04546.8 GAO85594.1 - 0.54 9.8 3.2 1 8.9 2.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Chromate_transp PF02417.10 GAO85595.1 - 0.055 13.0 0.4 0.071 12.7 0.3 1.2 1 0 0 1 1 1 0 Chromate transporter RasGEF PF00617.14 GAO85596.1 - 1.5e-06 28.0 0.1 0.00023 20.9 0.0 3.1 3 0 0 3 3 3 1 RasGEF domain Ribosomal_S4e PF00900.15 GAO85597.1 - 1.8e-33 114.0 0.3 3.4e-33 113.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAO85597.1 - 6e-18 64.4 4.7 1.2e-17 63.4 3.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 GAO85597.1 - 2.4e-06 26.8 0.0 4.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 GAO85597.1 - 0.00023 20.7 3.0 0.00023 20.7 2.1 2.9 3 0 0 3 3 3 1 KOW motif Semialdhyde_dhC PF02774.13 GAO85598.1 - 1.1e-35 123.2 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 GAO85598.1 - 1.6e-30 105.9 0.0 4.5e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 GAO85598.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 GAO85598.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD-oxidase_C PF02913.14 GAO85599.1 - 3.2e-64 216.6 0.0 5e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAO85599.1 - 6.6e-35 119.5 0.0 1.4e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain TMF_DNA_bd PF12329.3 GAO85600.1 - 0.00017 21.3 8.9 0.00017 21.3 6.2 5.1 2 1 3 5 5 5 3 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 GAO85600.1 - 0.00026 18.8 58.0 0.0014 16.4 40.1 1.9 1 1 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 GAO85600.1 - 0.1 11.7 21.2 0.02 14.1 3.6 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 GAO85600.1 - 0.34 9.9 53.2 0.064 12.3 6.7 3.4 1 1 2 3 3 3 0 Autophagy protein Apg6 RdRP PF05183.7 GAO85601.1 - 3.2e-189 630.3 0.1 5e-189 629.7 0.1 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 GAO85601.1 - 0.017 14.7 0.0 0.05 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.16 GAO85602.1 - 6.7e-94 315.2 0.0 9.8e-94 314.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 GAO85602.1 - 2e-21 75.7 3.6 2e-21 75.7 2.5 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 GAO85602.1 - 4.8e-19 68.3 0.0 2.8e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain ORF11CD3 PF10549.4 GAO85602.1 - 0.097 12.4 0.0 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 ORF11CD3 domain Slu7 PF11708.3 GAO85603.1 - 1.1e-82 277.4 12.8 1.1e-82 277.4 8.8 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 GAO85603.1 - 0.019 14.6 0.7 0.043 13.5 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 GAO85603.1 - 0.13 12.1 0.2 0.13 12.1 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L37e PF01907.14 GAO85604.1 - 5.2e-28 96.6 12.2 9.1e-28 95.8 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 GAO85604.1 - 0.0016 18.2 1.5 0.0025 17.5 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAO85604.1 - 0.13 11.8 2.4 3.6 7.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.3 GAO85604.1 - 0.29 11.1 2.5 0.47 10.4 1.7 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ISL3 PF14690.1 GAO85604.1 - 0.29 11.1 4.7 4.6 7.3 0.3 2.5 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 GAO85604.1 - 0.46 9.7 4.3 2 7.7 0.8 2.2 1 1 2 3 3 3 0 zinc-ribbon domain zf-C3HC4 PF00097.20 GAO85604.1 - 1.4 8.6 4.7 2.2 7.9 3.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO85604.1 - 1.8 8.6 4.7 3 7.9 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 GAO85604.1 - 2.8 7.3 10.0 2.8 7.4 0.8 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-HYPF PF07503.7 GAO85604.1 - 9.4 5.7 9.8 8.4 5.9 4.6 2.3 2 1 0 2 2 2 0 HypF finger DUF2348 PF09807.4 GAO85605.1 - 3.2e-05 23.1 0.0 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 GAO85605.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.13 GAO85606.1 - 5.5e-32 110.6 0.4 8.6e-32 110.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85606.1 - 1e-09 38.1 13.8 1.6e-09 37.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 GAO85606.1 - 1.7e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.19 GAO85607.1 - 2.7e-122 408.5 19.4 3.6e-122 408.1 13.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85607.1 - 1.5e-21 76.5 38.2 2.4e-13 49.5 9.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF441 PF04284.8 GAO85607.1 - 0.0044 16.8 1.3 0.0044 16.8 0.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF441) TRI12 PF06609.8 GAO85607.1 - 0.009 14.2 8.1 0.0071 14.5 1.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4066 PF13278.1 GAO85608.1 - 5.5e-16 58.2 0.0 6.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO85608.1 - 3.6e-08 32.9 0.0 4.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C65 PF10275.4 GAO85609.1 - 5.7e-69 232.1 0.0 6.9e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 GAO85609.1 - 0.076 13.5 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease PCI PF01399.22 GAO85610.1 - 4e-21 75.3 0.1 1.3e-20 73.6 0.1 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 GAO85610.1 - 6e-06 26.0 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 GAO85610.1 - 0.00093 18.9 1.0 0.21 11.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85610.1 - 0.0081 15.8 2.8 1 9.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO85610.1 - 0.015 14.8 1.4 0.51 10.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85610.1 - 0.016 15.1 4.3 0.18 11.7 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO85610.1 - 0.022 14.6 3.0 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 GAO85610.1 - 0.045 13.7 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Ras PF00071.17 GAO85611.1 - 8.2e-47 158.5 0.0 9.5e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO85611.1 - 8.9e-13 48.7 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO85611.1 - 2.2e-07 30.2 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAO85611.1 - 0.0057 15.8 0.0 0.0095 15.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region BPL_LplA_LipB PF03099.14 GAO85612.1 - 7.8e-08 32.3 0.1 2.5e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pyridox_oxidase PF01243.15 GAO85613.1 - 2.7e-12 46.5 0.0 8e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PI3K_1B_p101 PF10486.4 GAO85613.1 - 0.054 11.0 0.0 0.069 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pyridox_ox_2 PF12900.2 GAO85613.1 - 0.13 12.1 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase NIPSNAP PF07978.8 GAO85614.1 - 5.7e-39 132.2 6.3 2.8e-28 97.8 0.1 2.6 3 0 0 3 3 3 2 NIPSNAP Mfp-3 PF04202.8 GAO85614.1 - 0.065 13.4 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Foot protein 3 Ribosomal_S27e PF01667.12 GAO85615.1 - 1.1e-27 95.2 6.8 2e-27 94.5 4.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 GAO85615.1 - 0.14 12.0 1.2 0.24 11.2 0.8 1.4 1 0 0 1 1 1 0 IBR domain FSH1 PF03959.8 GAO85617.1 - 2.6e-74 249.2 0.0 3.1e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAO85617.1 - 8.1e-07 28.8 0.3 1.3e-06 28.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO85617.1 - 1.8e-06 28.0 2.2 0.0001 22.2 1.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAO85617.1 - 0.0034 16.8 0.0 2 7.8 0.1 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 GAO85617.1 - 0.0037 16.5 0.0 0.49 9.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family PCI PF01399.22 GAO85618.1 - 3.4e-20 72.3 0.0 1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain DUF3702 PF12486.3 GAO85618.1 - 0.055 13.1 1.8 0.67 9.6 0.0 3.2 3 0 0 3 3 3 0 ImpA domain protein FTA4 PF13093.1 GAO85618.1 - 1.6 8.1 8.0 0.34 10.3 2.8 2.1 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TP_methylase PF00590.15 GAO85619.1 - 2.1e-44 151.7 0.1 3.2e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 GAO85619.1 - 1.2e-11 44.7 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAO85619.1 - 3.3e-10 39.1 0.0 1.7e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CW_binding_2 PF04122.7 GAO85619.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Sirohm_synth_M PF14824.1 GAO85619.1 - 0.17 10.9 0.1 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF2763 PF10961.3 GAO85620.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DeoC PF01791.4 GAO85621.1 - 7.5e-47 159.5 3.4 8.7e-47 159.3 2.3 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 GAO85621.1 - 0.00085 18.3 2.3 0.0013 17.7 1.4 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 GAO85621.1 - 0.0048 16.1 0.3 0.0095 15.2 0.2 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.13 GAO85621.1 - 0.017 13.9 2.1 0.029 13.2 1.4 1.6 1 1 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.12 GAO85621.1 - 0.019 14.2 3.1 0.1 11.7 0.8 2.2 1 1 0 2 2 2 0 PcrB family WD40 PF00400.27 GAO85622.1 - 5.4e-13 48.2 9.5 4.9e-06 26.2 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat GAS PF13851.1 GAO85622.1 - 0.013 14.7 10.5 0.021 14.0 7.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nucleoporin_N PF08801.6 GAO85622.1 - 0.016 13.9 1.2 0.04 12.6 0.6 1.7 1 1 0 1 1 1 0 Nup133 N terminal like DUF1664 PF07889.7 GAO85622.1 - 0.1 12.4 1.5 0.18 11.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SDP_N PF12278.3 GAO85622.1 - 0.13 11.8 7.4 0.22 11.1 5.1 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Gryzun-like PF12742.2 GAO85622.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PQQ_3 PF13570.1 GAO85622.1 - 0.26 11.6 1.2 11 6.4 0.0 3.3 3 1 0 3 3 3 0 PQQ-like domain DUF3373 PF11853.3 GAO85622.1 - 0.35 9.3 3.5 0.5 8.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CorA PF01544.13 GAO85622.1 - 2.4 7.1 4.8 3.9 6.4 3.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Radical_SAM PF04055.16 GAO85624.1 - 2.3e-13 50.6 0.0 3.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.2 GAO85625.1 - 9.6e-15 55.2 0.0 1.4e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO85625.1 - 7.4e-13 49.4 0.1 2.6e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO85625.1 - 6.2e-09 35.8 0.0 8.1e-07 28.8 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAO85625.1 - 5.7e-08 33.1 0.0 1.5e-06 28.5 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAO85625.1 - 1.4e-05 24.3 0.0 0.00017 20.8 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 GAO85625.1 - 0.0021 17.0 0.2 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) PAPS_reduct PF01507.14 GAO85626.1 - 4.1e-45 153.7 0.1 9.3e-45 152.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 GAO85627.1 - 3.1e-86 288.1 0.1 4.4e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 GAO85627.1 - 2.5e-60 202.7 0.0 3.8e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 GAO85627.1 - 7.5e-54 181.4 0.0 1.3e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 GAO85627.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAO85627.1 - 0.026 14.3 0.3 0.057 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 GAO85627.1 - 0.055 13.0 0.0 0.5 9.9 0.0 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_12 PF13424.1 GAO85628.1 - 0.018 14.9 0.1 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO85628.1 - 0.068 13.1 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat hEGF PF12661.2 GAO85629.1 - 0.0041 17.0 1.8 0.0091 16.0 1.3 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF Phospholamban PF04272.9 GAO85629.1 - 4.1 6.9 7.0 11 5.5 4.9 1.7 1 0 0 1 1 1 0 Phospholamban Complex1_LYR_1 PF13232.1 GAO85631.1 - 9.9e-18 64.1 6.3 9.9e-18 64.1 4.4 1.9 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAO85631.1 - 2.7e-16 59.0 5.6 2.7e-16 59.0 3.9 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 GAO85631.1 - 0.15 12.5 1.9 0.37 11.3 1.4 1.6 1 0 0 1 1 1 0 Complex1_LYR-like SET PF00856.23 GAO85632.1 - 3.5e-17 63.1 1.1 3.5e-17 63.1 0.8 4.0 3 3 0 3 3 3 1 SET domain zf-DHHC PF01529.15 GAO85633.1 - 3e-36 124.4 1.9 5.6e-36 123.5 0.7 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase B12D PF06522.6 GAO85634.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PMT PF02366.13 GAO85635.1 - 4.2e-80 268.6 18.4 4.6e-80 268.5 11.7 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAO85635.1 - 7.8e-57 191.8 0.0 1.6e-56 190.8 0.0 1.6 1 0 0 1 1 1 1 MIR domain DUF4231 PF14015.1 GAO85635.1 - 3.5 7.6 7.7 19 5.3 5.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) PRP21_like_P PF12230.3 GAO85636.1 - 3.3e-65 219.7 9.9 6e-65 218.9 6.9 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 GAO85636.1 - 2.4e-38 129.5 2.9 6.3e-20 70.5 0.1 2.5 2 0 0 2 2 2 2 Surp module DUF1517 PF07466.6 GAO85636.1 - 0.059 12.3 0.7 0.094 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Sec2p PF06428.6 GAO85637.1 - 3.1e-28 97.5 14.2 3.1e-28 97.5 9.8 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 GAO85637.1 - 0.022 12.0 25.8 0.031 11.6 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CorA PF01544.13 GAO85637.1 - 0.21 10.5 6.9 0.38 9.7 4.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1759 PF03564.10 GAO85637.1 - 1.2 8.9 8.4 0.24 11.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) V_ATPase_I PF01496.14 GAO85637.1 - 1.2 6.8 10.1 1.8 6.3 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 GAO85637.1 - 3.8 5.7 13.9 5.6 5.2 9.7 1.1 1 0 0 1 1 1 0 Peptidase S46 dsDNA_bind PF01984.15 GAO85638.1 - 2.3e-37 127.2 17.0 2.6e-37 127.0 11.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 GAO85638.1 - 0.0075 16.4 1.4 0.0098 16.1 0.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4615) PIN_3 PF13470.1 GAO85638.1 - 0.082 13.5 0.9 0.14 12.8 0.6 1.7 1 1 0 1 1 1 0 PIN domain DUF4011 PF13195.1 GAO85638.1 - 0.41 10.6 4.6 0.48 10.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Med4 PF10018.4 GAO85638.1 - 3.8 6.8 10.1 16 4.7 7.0 1.8 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Coq4 PF05019.8 GAO85639.1 - 1.7e-100 334.5 0.0 2.1e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 GAO85640.1 - 7e-19 68.7 0.0 1e-18 68.1 0.0 1.2 1 0 0 1 1 1 1 SET domain ApbA_C PF08546.6 GAO85641.1 - 1.5e-34 118.6 0.2 2.3e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAO85641.1 - 4.2e-25 87.9 0.0 8.6e-24 83.6 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAO85641.1 - 0.12 12.0 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sas10_Utp3 PF04000.10 GAO85642.1 - 2.7e-19 69.1 2.3 3.3e-19 68.8 0.1 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF936 PF06075.7 GAO85642.1 - 0.066 12.1 17.0 0.069 12.0 11.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2076 PF09849.4 GAO85643.1 - 5.4e-09 36.4 8.6 6.4e-09 36.2 6.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 GAO85643.1 - 0.00027 20.7 2.0 0.00042 20.1 1.4 1.3 1 0 0 1 1 1 1 CHCH domain GKAP PF03359.8 GAO85643.1 - 0.73 9.3 4.5 1.5 8.4 3.1 1.5 1 1 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein AflR PF08493.5 GAO85643.1 - 3.7 6.4 13.1 6.8 5.6 9.1 1.4 1 1 0 1 1 1 0 Aflatoxin regulatory protein UBX PF00789.15 GAO85644.1 - 6.4e-09 35.7 0.1 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain SAGA-Tad1 PF12767.2 GAO85644.1 - 0.42 10.2 7.0 0.031 13.9 0.6 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SURF1 PF02104.10 GAO85645.1 - 1.1e-66 224.6 0.0 1.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 GAO85646.1 - 8.6e-106 354.6 10.3 1.2e-105 354.1 7.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 GAO85646.1 - 9.7e-09 35.2 0.2 1.6e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 GAO85646.1 - 1.3e-05 25.2 0.2 2.3e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAO85646.1 - 0.019 14.9 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_Tnp_IS66 PF03050.9 GAO85646.1 - 0.049 12.8 0.1 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 Transposase IS66 family CMS1 PF14617.1 GAO85647.1 - 3.2e-81 272.1 7.3 5.8e-81 271.2 5.1 1.4 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 GAO85647.1 - 1.1e-05 24.9 0.3 1.3e-05 24.7 0.2 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Dicty_REP PF05086.7 GAO85647.1 - 0.1 10.3 5.7 0.13 9.9 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.5 GAO85647.1 - 0.41 8.9 3.0 0.49 8.7 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PDE6_gamma PF04868.7 GAO85647.1 - 1.4 8.8 6.4 0.48 10.3 2.1 2.0 2 1 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit GAGA_bind PF06217.7 GAO85647.1 - 2.9 7.7 11.3 4.4 7.1 7.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 GAO85647.1 - 4.5 7.0 8.6 7.1 6.3 6.0 1.3 1 0 0 1 1 1 0 DDHD domain RRM_1 PF00076.17 GAO85648.1 - 4.3e-13 48.7 0.0 1.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85648.1 - 7.6e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3987 PF13148.1 GAO85648.1 - 0.0054 15.3 3.5 0.0054 15.3 2.4 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF3987) Ras PF00071.17 GAO85649.1 - 1.3e-46 157.9 0.0 1.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO85649.1 - 1.1e-10 42.0 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Fungal_trans PF04082.13 GAO85649.1 - 1.2e-07 30.8 0.2 3.4e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arf PF00025.16 GAO85649.1 - 0.018 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family RhoGAP PF00620.22 GAO85650.1 - 1.3e-50 170.9 0.0 9e-50 168.2 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 GAO85650.1 - 3.5e-15 55.9 1.3 4.9e-15 55.4 0.1 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FH2 PF02181.18 GAO85650.1 - 0.013 14.4 0.4 0.021 13.7 0.3 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain APG6 PF04111.7 GAO85650.1 - 8.2 5.3 7.6 0.52 9.2 0.2 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 MBA1 PF07961.6 GAO85651.1 - 8.5e-08 31.3 0.0 1.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 GAO85651.1 - 0.00083 19.3 0.1 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 Tim44-like domain SUI1 PF01253.17 GAO85652.1 - 4.4e-29 100.1 5.7 6.2e-29 99.6 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 UPF0139 PF03669.8 GAO85652.1 - 0.00043 19.7 0.5 0.00069 19.0 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 GAO85653.1 - 2.1e-27 94.8 0.5 7.3e-27 93.1 0.3 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RRM_1 PF00076.17 GAO85654.1 - 3.7e-08 32.8 0.1 8.6e-07 28.4 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85654.1 - 1.2e-05 25.0 0.0 0.00041 20.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85654.1 - 4e-05 23.5 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 GAO85655.1 - 5.1e-38 130.3 0.0 3e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 GAO85656.1 - 7.6e-82 274.1 0.0 1.2e-81 273.5 0.0 1.2 1 1 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 GAO85657.1 - 3.7e-36 122.8 1.9 3.7e-36 122.8 1.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 GAO85657.1 - 0.0049 16.7 3.3 2 8.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85657.1 - 0.18 11.7 10.7 2.6 8.0 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO85657.1 - 0.8 10.3 5.3 64 4.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat COX6A PF02046.10 GAO85658.1 - 9.5e-46 154.4 1.6 1e-45 154.4 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.18 GAO85659.1 - 7e-13 49.0 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAO85659.1 - 1.6e-08 34.1 0.1 2.2e-07 30.4 0.0 2.8 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 GAO85659.1 - 0.0023 17.7 0.9 0.0067 16.3 0.6 1.8 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 GAO85660.1 - 8.3e-22 77.2 1.5 1.5e-21 76.4 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAO85660.1 - 1.7e-07 31.4 0.3 5.3e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain ANTH PF07651.11 GAO85661.1 - 3.8e-77 258.7 0.0 3.8e-77 258.7 0.0 2.9 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 GAO85661.1 - 8.8e-65 217.2 7.1 8.8e-65 217.2 4.9 5.6 4 2 2 6 6 6 1 I/LWEQ domain ENTH PF01417.15 GAO85661.1 - 9.5e-05 22.2 0.1 0.00061 19.6 0.0 2.5 2 0 0 2 2 2 1 ENTH domain DUF2404 PF10296.4 GAO85662.1 - 5.6e-32 109.7 0.0 1.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) polyprenyl_synt PF00348.12 GAO85663.1 - 2.5e-51 174.0 0.0 7.9e-49 165.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase SQS_PSY PF00494.14 GAO85663.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 1 0 1 1 1 0 Squalene/phytoene synthase HEPPP_synt_1 PF07307.6 GAO85663.1 - 0.036 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Rpn3_C PF08375.6 GAO85664.1 - 2.1e-24 85.6 0.4 2.1e-24 85.6 0.3 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 GAO85664.1 - 3.4e-20 72.3 0.3 1.8e-19 70.0 0.0 2.3 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 GAO85664.1 - 0.00079 19.2 0.5 0.0085 15.8 0.1 2.6 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 GAO85665.1 - 1.2e-65 221.8 6.4 1.2e-65 221.8 4.4 3.8 3 1 0 3 3 3 1 DASH complex subunit Spc34 TFIID_20kDa PF03847.8 GAO85665.1 - 6.4e-21 74.4 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ISG65-75 PF11727.3 GAO85665.1 - 0.0047 16.0 2.7 1.1 8.2 0.1 2.4 2 0 0 2 2 2 2 Invariant surface glycoprotein PIP5K PF01504.13 GAO85666.1 - 4.8e-87 291.2 0.0 7.9e-87 290.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.14 GAO85667.1 - 7.2e-21 74.0 1.7 1.5e-20 73.0 0.5 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Herpes_BLLF1 PF05109.8 GAO85667.1 - 2.1 6.1 22.9 2.6 5.9 15.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) XPG_N PF00752.12 GAO85668.1 - 6e-32 109.9 0.9 1.9e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 GAO85668.1 - 2.1e-31 107.8 0.0 5.4e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 GAO85668.1 - 1.5e-06 28.3 0.2 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 GAO85668.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zn_clus PF00172.13 GAO85669.1 - 3.9e-09 36.2 9.5 6.1e-09 35.6 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO85669.1 - 1.8e-07 30.3 1.5 4.3e-07 29.0 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3327 PF11806.3 GAO85669.1 - 0.058 13.7 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) UQ_con PF00179.21 GAO85670.1 - 1.4e-45 154.1 0.1 2.3e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyl-CoA_dh_N PF02771.11 GAO85670.1 - 8.8e-26 90.7 0.1 1.8e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 GAO85670.1 - 1.7e-24 86.6 0.5 2.9e-24 85.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO85670.1 - 3.1e-18 65.0 0.0 5.9e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO85670.1 - 1.5e-09 38.2 0.9 2.4e-09 37.5 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.1 GAO85670.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO85670.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Glyoxalase_2 PF12681.2 GAO85671.1 - 5.4e-09 36.6 0.0 1.4e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAO85671.1 - 0.00015 21.7 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly-zipper_Omp PF13488.1 GAO85671.1 - 0.0026 17.3 0.4 0.0026 17.3 0.3 1.8 2 0 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.10 GAO85671.1 - 0.0058 16.2 0.2 0.0058 16.2 0.1 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 GAO85671.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.1 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain EMG1 PF03587.9 GAO85672.1 - 1e-78 263.2 0.0 1.2e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF2813 PF11398.3 GAO85672.1 - 0.11 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Acetyltransf_13 PF13880.1 GAO85673.1 - 3.2e-30 103.6 0.0 8e-30 102.3 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 GAO85673.1 - 2e-17 62.4 0.8 4.1e-17 61.4 0.3 1.8 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO FAD_binding_4 PF01565.18 GAO85675.1 - 0.01 15.3 0.3 0.02 14.3 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain eIF2A PF08662.6 GAO85676.1 - 3.5e-84 281.3 0.0 2.9e-83 278.3 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 GAO85676.1 - 0.00014 21.5 0.7 0.49 10.3 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 GAO85676.1 - 0.018 15.1 0.9 0.018 15.1 0.6 3.7 2 1 2 4 4 4 0 Carnitine deficiency-associated protein 3 Apc1 PF12859.2 GAO85678.1 - 1.8e-33 114.8 0.7 5.2e-33 113.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 GAO85678.1 - 1.3e-06 28.2 6.7 0.13 12.5 0.0 4.7 4 0 0 4 4 4 3 Proteasome/cyclosome repeat RPAP1_C PF08620.5 GAO85679.1 - 4.2e-29 100.2 0.0 7.3e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 GAO85679.1 - 7e-20 70.3 5.3 1.6e-19 69.2 3.7 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 GAO85680.1 - 9.7e-15 54.1 0.1 2.4e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Pkinase PF00069.20 GAO85681.1 - 1.2e-60 204.9 0.0 1.5e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85681.1 - 4.5e-36 124.2 0.0 6.2e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85681.1 - 1.9e-05 23.7 0.0 3.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAO85681.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 GAO85681.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAO85681.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SH2_2 PF14633.1 GAO85682.1 - 9.9e-83 276.5 0.0 3.1e-82 274.9 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 GAO85682.1 - 4.4e-37 126.7 5.0 4.4e-37 126.7 3.5 3.4 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 GAO85682.1 - 1.4e-31 109.0 0.0 4.5e-31 107.4 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 GAO85682.1 - 5.3e-30 103.6 0.1 1.1e-29 102.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 GAO85682.1 - 3.7e-19 68.9 3.5 3.7e-19 68.9 2.4 2.9 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 GAO85682.1 - 3.5e-17 62.3 31.5 3.5e-17 62.3 21.9 7.0 5 2 2 7 7 7 1 Acidic N-terminal SPT6 SH2 PF00017.19 GAO85682.1 - 2.3e-05 24.0 0.0 6.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 GAO85682.1 - 0.00066 19.5 0.0 0.0021 17.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.14 GAO85682.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DUF2716 PF10898.3 GAO85682.1 - 0.028 14.4 0.2 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Oxysterol_BP PF01237.13 GAO85683.1 - 9.7e-120 399.2 0.0 2.1e-119 398.1 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 GAO85683.1 - 3.1e-40 136.1 0.2 6.8e-40 135.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAO85683.1 - 3.2e-07 30.5 0.1 7.2e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAO85683.1 - 9.7e-06 25.8 1.7 0.00018 21.7 1.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAO85683.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PH domain IFRD PF05004.8 GAO85684.1 - 1.4e-31 109.7 2.7 1.8e-31 109.3 1.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 GAO85684.1 - 0.0082 16.4 0.3 0.71 10.1 0.0 2.8 1 1 0 2 2 2 1 HEAT repeats Cnd3 PF12719.2 GAO85684.1 - 0.022 13.7 0.2 0.05 12.5 0.2 1.7 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 GAO85684.1 - 0.045 14.2 0.6 2.6 8.6 0.1 3.1 2 1 1 3 3 3 0 HEAT-like repeat Adaptin_N PF01602.15 GAO85684.1 - 0.06 11.6 0.8 0.2 9.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.17 GAO85684.1 - 0.063 13.3 0.7 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Corona_nucleoca PF00937.13 GAO85684.1 - 0.13 11.2 3.1 0.22 10.4 2.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ECR1_N PF14382.1 GAO85685.1 - 5.1e-11 41.6 0.0 1.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 GAO85685.1 - 9.4e-05 22.2 0.1 0.0013 18.6 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Ino80_Iec3 PF14612.1 GAO85686.1 - 3.8e-98 328.1 2.1 4.8e-98 327.8 1.5 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sec34 PF04136.10 GAO85686.1 - 0.028 14.0 0.9 0.048 13.3 0.6 1.3 1 0 0 1 1 1 0 Sec34-like family RRM_6 PF14259.1 GAO85687.1 - 3.5e-23 81.3 0.0 1.6e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO85687.1 - 2.1e-21 75.3 0.6 2.6e-13 49.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85687.1 - 5.7e-08 32.4 0.6 0.00038 20.2 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT6_acidic PF14632.1 GAO85687.1 - 0.00019 21.5 2.2 0.00019 21.5 1.5 2.6 2 0 0 2 2 2 1 Acidic N-terminal SPT6 Nup35_RRM_2 PF14605.1 GAO85687.1 - 0.0052 16.5 0.1 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRS1 PF04939.7 GAO85687.1 - 0.029 13.8 1.1 0.029 13.8 0.8 2.2 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Btz PF09405.5 GAO85688.1 - 2.3e-37 127.9 1.9 6.8e-37 126.4 1.3 1.9 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 GAO85689.1 - 2.5e-19 68.5 53.4 1.4e-07 30.9 4.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Arylesterase PF01731.15 GAO85690.1 - 0.00031 20.6 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 Arylesterase TPM PF04536.9 GAO85690.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase LETM1 PF07766.8 GAO85691.1 - 1.9e-05 23.8 2.1 0.052 12.5 0.1 2.5 1 1 2 3 3 3 2 LETM1-like protein PAS_9 PF13426.1 GAO85692.1 - 8.3e-33 112.8 0.0 2.3e-17 63.2 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 GAO85692.1 - 3.2e-23 81.6 0.0 2.5e-10 40.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 GAO85692.1 - 2.6e-14 52.9 0.0 0.0019 17.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.1 GAO85692.1 - 1.1e-13 51.0 0.0 2.3e-07 30.7 0.0 2.7 3 0 0 3 3 3 2 PAS domain GATA PF00320.22 GAO85692.1 - 1.2e-13 50.0 7.3 2.6e-13 49.0 5.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 GAO85692.1 - 2.1e-11 43.8 0.0 0.0019 18.1 0.0 4.4 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 GAO85692.1 - 0.0024 17.6 0.0 0.17 11.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain Ras PF00071.17 GAO85693.1 - 9.6e-27 93.3 0.0 2.4e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAO85693.1 - 0.00013 22.4 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Zn_clus PF00172.13 GAO85694.1 - 2.8e-09 36.7 12.2 6.1e-09 35.6 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 GAO85695.1 - 6.8e-59 199.4 0.0 8.6e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase QRPTase_C PF01729.14 GAO85696.1 - 4.8e-49 166.1 0.1 2.3e-47 160.6 0.1 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 GAO85696.1 - 5.3e-25 87.0 0.0 1.5e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 GAO85696.1 - 0.056 12.5 0.0 0.2 10.7 0.0 1.8 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Mto2_bdg PF12808.2 GAO85697.1 - 2.7e-27 94.6 32.6 7.4e-20 70.7 14.7 11.8 10 3 1 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 GAO85697.1 - 4.5e-24 84.0 12.4 4.5e-24 84.0 8.6 7.0 5 1 2 7 7 7 1 Microtubule associated Reo_sigmaC PF04582.7 GAO85697.1 - 2.5e-07 30.2 2.3 2.5e-07 30.2 1.6 5.7 5 1 1 6 6 6 2 Reovirus sigma C capsid protein AHS1 PF02682.11 GAO85697.1 - 5.4 6.4 6.1 3.9 6.8 0.3 2.9 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 Sec7 PF01369.15 GAO85698.1 - 9.4e-27 93.9 0.0 4.9e-25 88.3 0.0 2.4 1 1 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAO85698.1 - 9.6e-20 70.9 0.0 2.4e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain UNC-50 PF05216.8 GAO85699.1 - 3.6e-66 222.6 2.0 4.7e-66 222.3 1.4 1.1 1 0 0 1 1 1 1 UNC-50 family DUF962 PF06127.6 GAO85699.1 - 0.049 13.5 0.0 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) YobH PF13996.1 GAO85699.1 - 0.15 12.0 0.8 0.46 10.4 0.5 1.9 1 0 0 1 1 1 0 YobH-like protein PP28 PF10252.4 GAO85700.1 - 3.7e-34 116.5 13.0 3.7e-34 116.5 9.0 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 MFS_1 PF07690.11 GAO85701.1 - 9.2e-21 73.9 57.0 1.6e-19 69.8 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_20 PF00982.16 GAO85702.1 - 1.1e-139 466.0 0.1 9.3e-139 462.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAO85702.1 - 1.5e-91 305.5 0.0 3e-91 304.5 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 GAO85702.1 - 0.0081 15.7 0.0 2.8 7.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PAP_assoc PF03828.14 GAO85703.1 - 0.00029 20.7 0.0 0.00085 19.2 0.0 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase PLDc PF00614.17 GAO85704.1 - 4.5e-14 51.7 0.5 8.2e-07 28.6 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAO85704.1 - 8.7e-12 44.8 0.0 1.1e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 GAO85704.1 - 6e-09 35.6 0.5 2.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 GAO85705.1 - 1.2e-05 25.3 0.5 1.5e-05 25.0 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85705.1 - 3.7e-05 23.5 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Helicase_C_2 PF13307.1 GAO85706.1 - 6.8e-56 188.7 0.0 1.3e-55 187.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 GAO85706.1 - 5.8e-47 159.3 0.1 1e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L18e PF00828.14 GAO85706.1 - 5.6e-32 110.8 0.0 1.1e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DEAD PF00270.24 GAO85706.1 - 0.0023 17.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 GAO85706.1 - 0.023 14.5 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sel1 PF08238.7 GAO85707.1 - 5.4e-18 65.0 26.4 7.6e-08 32.7 0.2 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_1 PF00515.23 GAO85707.1 - 4.7e-05 22.8 0.1 0.00029 20.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85707.1 - 0.00071 19.3 1.0 0.01 15.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAO85707.1 - 0.0013 18.3 0.5 0.0013 18.3 0.3 2.8 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 GAO85707.1 - 0.28 11.9 6.3 0.36 11.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85707.1 - 0.35 10.8 2.7 0.91 9.5 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Bromodomain PF00439.20 GAO85708.1 - 2.2e-39 133.2 6.0 1.2e-20 73.1 0.4 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 GAO85708.1 - 9e-17 60.9 0.9 1.7e-16 60.0 0.6 1.5 1 0 0 1 1 1 1 BAH domain DUF1353 PF07087.6 GAO85708.1 - 0.019 14.4 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Nucleoplasmin PF03066.10 GAO85708.1 - 0.24 10.9 9.2 0.58 9.6 6.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAO85708.1 - 0.41 8.4 2.7 0.79 7.5 1.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OTU PF02338.14 GAO85709.1 - 4.9e-13 49.7 0.0 1.2e-12 48.5 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAO85709.1 - 0.033 13.5 0.0 0.12 11.7 0.0 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain Pkinase PF00069.20 GAO85710.1 - 8.9e-41 139.7 0.0 3.3e-19 69.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85710.1 - 5.3e-09 35.5 0.0 0.0002 20.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 GAO85710.1 - 0.011 15.4 1.7 0.95 9.1 0.0 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO85710.1 - 0.029 13.3 0.0 4.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Cnd1_N PF12922.2 GAO85711.1 - 9.1e-60 201.1 1.6 1.1e-59 200.8 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 GAO85711.1 - 4.3e-56 189.5 2.1 1.3e-50 171.7 0.3 3.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAO85711.1 - 1.6e-11 44.2 4.4 5.8e-06 26.5 0.0 4.8 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 GAO85711.1 - 2.4e-09 36.4 7.4 0.063 13.3 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 GAO85711.1 - 2.3e-06 27.9 7.7 0.028 14.9 0.0 6.2 7 1 1 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.15 GAO85711.1 - 2.7e-06 26.0 9.1 0.3 9.3 0.9 4.3 3 2 1 4 4 4 3 Adaptin N terminal region DUF2435 PF10363.4 GAO85711.1 - 0.00032 20.5 0.0 0.59 10.0 0.0 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 GAO85711.1 - 0.057 13.3 3.4 6.9 6.7 0.3 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 GAO85711.1 - 0.074 12.0 8.5 0.088 11.7 1.8 3.7 2 2 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Oxysterol_BP PF01237.13 GAO85712.1 - 6.6e-57 192.5 0.0 1.7e-56 191.2 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein U1snRNP70_N PF12220.3 GAO85712.1 - 0.94 9.8 4.5 31 4.9 0.0 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Peptidase_C12 PF01088.16 GAO85713.1 - 8.5e-15 54.5 0.3 2.3e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DegQ PF08181.6 GAO85713.1 - 0.017 14.8 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family I-set PF07679.11 GAO85714.1 - 0.00039 20.2 0.2 0.31 10.9 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin I-set domain Vinculin PF01044.14 GAO85714.1 - 0.14 10.1 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 Vinculin family Nrap PF03813.9 GAO85715.1 - 0 1264.4 0.0 0 1264.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 GAO85716.1 - 1e-31 109.6 0.0 3.3e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme BSD PF03909.12 GAO85716.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 BSD domain Aminotran_1_2 PF00155.16 GAO85716.1 - 0.075 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II MRP-L20 PF12824.2 GAO85717.1 - 1.5e-66 223.4 6.9 1.7e-66 223.1 4.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.23 GAO85718.1 - 6.4e-31 107.3 0.0 1.2e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO85718.1 - 8e-14 51.3 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 GAO85719.1 - 5.5e-27 94.4 0.3 1.9e-25 89.4 0.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAO85719.1 - 6e-20 72.4 3.1 6e-20 72.4 2.1 4.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 GAO85719.1 - 2.4e-10 40.8 0.9 1e-06 28.9 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO85719.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 GAO85719.1 - 0.00036 19.6 0.2 0.00036 19.6 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 GAO85719.1 - 0.076 12.9 2.1 13 5.7 0.2 3.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 GAO85719.1 - 0.1 12.8 0.2 0.1 12.8 0.1 5.6 3 2 1 4 4 4 0 ABC transporter WEMBL PF05701.6 GAO85719.1 - 3 6.1 71.2 0.2 10.0 22.3 2.4 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 GAO85719.1 - 8.9 5.3 21.0 0.83 8.7 0.3 4.4 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DEAD PF00270.24 GAO85720.1 - 3e-41 140.7 0.0 4.3e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO85720.1 - 8.2e-24 83.2 0.1 1.5e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 GAO85721.1 - 7.6e-52 173.0 3.8 2e-23 81.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein RF-1 PF00472.15 GAO85722.1 - 1.6e-34 118.1 0.9 2.4e-34 117.5 0.6 1.2 1 0 0 1 1 1 1 RF-1 domain DUF3322 PF11795.3 GAO85722.1 - 0.045 13.4 0.3 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DnaJ PF00226.26 GAO85723.1 - 1.6e-24 85.3 1.5 1.6e-24 85.3 1.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 GAO85723.1 - 3.3e-20 71.5 8.9 2.1e-08 33.7 0.1 6.6 4 3 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 GAO85723.1 - 2.3e-17 61.4 2.7 0.00023 20.8 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAO85723.1 - 3.5e-16 58.0 0.1 2.1e-06 27.1 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO85723.1 - 2.1e-14 53.7 17.6 3.8e-05 24.2 3.5 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85723.1 - 2.1e-13 49.5 16.0 0.0059 17.1 1.1 7.1 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAO85723.1 - 7e-12 45.0 12.5 1.4e-05 24.8 1.4 4.8 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAO85723.1 - 7.5e-10 39.0 4.6 0.0014 18.9 0.0 4.9 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAO85723.1 - 1.7e-07 31.2 8.5 1.9 9.1 0.0 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO85723.1 - 9.5e-06 25.0 0.0 0.15 11.9 0.0 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO85723.1 - 7.3e-05 22.8 7.3 0.073 13.2 0.1 4.8 4 3 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAO85723.1 - 0.00074 19.5 0.1 0.22 11.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85723.1 - 0.0013 18.6 12.7 0.044 13.7 0.4 5.4 4 3 3 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85723.1 - 0.0051 16.5 6.0 43 4.2 0.0 5.7 3 2 2 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 GAO85723.1 - 0.012 15.0 2.6 0.094 12.1 0.2 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.12 GAO85723.1 - 0.059 13.6 12.0 0.12 12.6 0.0 4.0 2 2 1 3 3 3 0 Bacterial transcriptional activator domain DUF802 PF05650.6 GAO85723.1 - 0.13 12.4 2.4 0.32 11.1 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Enkurin PF13864.1 GAO85723.1 - 7.9 6.7 10.9 0.72 10.0 2.1 2.9 3 0 0 3 3 3 0 Calmodulin-binding PCMT PF01135.14 GAO85724.1 - 6.1e-54 182.7 0.0 1.6e-53 181.4 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAO85724.1 - 2.5e-10 40.9 0.0 3.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85724.1 - 8.7e-09 35.1 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO85724.1 - 3.6e-06 26.7 0.0 6.8e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO85724.1 - 4.3e-06 26.7 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO85724.1 - 5.6e-06 26.6 0.0 8.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAO85724.1 - 4.5e-05 23.1 0.0 6.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO85724.1 - 0.0021 18.4 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO85724.1 - 0.0038 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 GAO85724.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAO85724.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAO85724.1 - 0.046 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 GAO85724.1 - 0.05 12.6 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 GAO85724.1 - 0.078 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 GAO85724.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 2-oxoacid_dh PF00198.18 GAO85726.1 - 1.9e-80 269.4 0.0 2.8e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAO85726.1 - 1e-19 69.9 2.3 2e-19 68.9 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 GAO85726.1 - 0.00032 19.9 2.1 0.0094 15.1 0.1 2.5 1 1 2 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.1 GAO85726.1 - 0.003 17.2 0.2 0.035 13.8 0.0 2.3 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 GAO85726.1 - 0.0035 16.9 0.5 0.13 11.9 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.14 GAO85726.1 - 0.011 15.3 0.4 0.026 14.1 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.1 GAO85726.1 - 0.013 15.8 0.2 0.71 10.2 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF605 PF04652.11 GAO85726.1 - 0.1 11.9 11.3 0.13 11.6 7.8 1.1 1 0 0 1 1 1 0 Vta1 like PRCC PF10253.4 GAO85726.1 - 0.25 11.9 4.9 0.51 11.0 3.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2360 PF10152.4 GAO85726.1 - 0.56 10.4 7.9 0.91 9.7 5.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_60s PF00428.14 GAO85726.1 - 1.2 9.6 4.6 6.2 7.2 3.2 2.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein Histone PF00125.19 GAO85727.1 - 8.4e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAO85727.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO85728.1 - 2.9e-22 78.5 0.3 4.1e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAO85728.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 GAO85728.1 - 0.00041 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 GAO85728.1 - 0.023 14.1 0.1 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.14 GAO85729.1 - 7.9e-88 294.1 0.0 1.6e-85 286.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase family C54 R3H PF01424.17 GAO85730.1 - 3.8e-12 45.7 0.1 9.6e-12 44.4 0.1 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 GAO85730.1 - 1.6e-07 30.9 0.2 3.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAO85730.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site zf-met PF12874.2 GAO85731.1 - 1.3e-09 37.8 8.8 3.3e-06 27.0 1.0 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAO85731.1 - 9.3e-09 35.3 1.5 0.00018 21.5 0.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 GAO85731.1 - 6.2e-08 32.5 5.1 1.7e-07 31.1 1.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAO85731.1 - 7.4e-05 22.8 7.4 0.014 15.7 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ground-like PF04155.13 GAO85731.1 - 0.00069 19.8 0.2 0.032 14.5 0.0 2.7 2 0 0 2 2 2 1 Ground-like domain zf-C2H2_4 PF13894.1 GAO85731.1 - 0.0017 18.5 4.9 0.64 10.4 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAO85731.1 - 0.024 14.5 7.0 1.1 9.2 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 GAO85731.1 - 0.13 11.9 1.0 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif AAA_11 PF13086.1 GAO85731.1 - 7.1 6.1 7.7 86 2.5 5.3 2.2 1 1 0 1 1 1 0 AAA domain COG2 PF06148.6 GAO85732.1 - 0.00014 21.7 3.3 0.00021 21.1 2.3 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.1 GAO85732.1 - 0.0011 18.6 6.5 0.0016 18.1 4.5 1.2 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 COG5 PF10392.4 GAO85732.1 - 0.005 16.8 1.0 0.0066 16.4 0.7 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 CtIP_N PF10482.4 GAO85732.1 - 0.021 14.6 7.7 0.021 14.6 5.3 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FKBP_N PF01346.13 GAO85732.1 - 0.021 14.8 2.8 0.034 14.1 1.9 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Herpes_ICP4_N PF03584.10 GAO85732.1 - 0.046 13.2 1.1 0.089 12.3 0.7 1.5 1 1 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Muted PF14942.1 GAO85732.1 - 0.061 13.1 6.5 0.083 12.7 4.5 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.4 GAO85732.1 - 0.089 11.7 7.3 0.12 11.3 5.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RecX PF02631.11 GAO85732.1 - 0.1 12.7 4.3 0.21 11.7 3.0 1.6 1 0 0 1 1 1 0 RecX family GST_C PF00043.20 GAO85732.1 - 0.2 11.6 4.1 4.4 7.3 2.9 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain V_ATPase_I PF01496.14 GAO85732.1 - 0.2 9.4 3.9 0.23 9.2 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YPEB PF14620.1 GAO85732.1 - 0.23 10.4 4.0 0.31 10.0 2.8 1.2 1 0 0 1 1 1 0 YpeB sporulation IncA PF04156.9 GAO85732.1 - 0.48 10.0 10.6 0.7 9.4 7.3 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 GAO85732.1 - 0.69 8.9 11.2 0.8 8.6 7.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2743 PF10899.3 GAO85732.1 - 0.69 9.2 3.2 0.97 8.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2743) DUF342 PF03961.8 GAO85732.1 - 0.7 8.2 7.1 0.84 7.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 GAO85732.1 - 0.93 9.8 7.7 1.5 9.2 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Spc24 PF08286.6 GAO85732.1 - 1 9.0 6.3 2.4 7.8 4.4 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.4 GAO85732.1 - 2 8.3 12.0 2.9 7.8 8.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 COG5 PF10392.4 GAO85733.1 - 0.012 15.6 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1818 PF08848.6 GAO85733.1 - 0.045 13.8 1.5 0.08 13.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) COG2 PF06148.6 GAO85733.1 - 0.051 13.4 1.4 0.075 12.9 1.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3819 PF12842.2 GAO85733.1 - 0.08 12.6 0.2 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) Rad4 PF03835.10 GAO85733.1 - 0.086 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain IncA PF04156.9 GAO85733.1 - 0.12 11.9 4.8 0.14 11.7 3.3 1.2 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 GAO85733.1 - 0.19 11.4 2.7 0.28 10.8 1.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 NUDE_C PF04880.8 GAO85733.1 - 1.4 9.2 3.7 13 6.1 2.9 1.9 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Atg14 PF10186.4 GAO85733.1 - 1.5 7.6 11.1 2.6 6.9 7.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sugar_tr PF00083.19 GAO85734.1 - 4.6e-106 355.0 28.3 5.3e-106 354.8 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85734.1 - 1.6e-21 76.4 38.7 1e-12 47.4 8.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BBS2_N PF14781.1 GAO85736.1 - 0.097 12.2 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 GAO85736.1 - 0.28 11.1 6.7 1.4 8.8 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Clr5 PF14420.1 GAO85737.1 - 0.0041 16.9 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Clr5 domain TAXi_C PF14541.1 GAO85737.1 - 0.069 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DHO_dh PF01180.16 GAO85737.1 - 0.075 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF2335 PF10097.4 GAO85737.1 - 1.6 8.4 6.3 6.7 6.4 4.4 2.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Het-C PF07217.6 GAO85738.1 - 1.2e-274 912.2 0.0 1.5e-274 911.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FAD-oxidase_C PF02913.14 GAO85739.1 - 2.7e-58 197.2 0.0 4.1e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAO85739.1 - 2.2e-37 127.6 0.0 4.7e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.7 GAO85740.1 - 1.4e-34 118.1 0.3 3.2e-34 116.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO85740.1 - 8.2e-24 83.6 0.4 1.3e-23 82.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAO85740.1 - 0.00084 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 GAO85740.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.9 GAO85740.1 - 0.0029 16.9 0.1 0.0047 16.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAO85740.1 - 0.0071 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO85740.1 - 0.009 15.1 0.5 0.013 14.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 GAO85740.1 - 0.037 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 GAO85740.1 - 0.056 13.9 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 GAO85740.1 - 0.085 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ras PF00071.17 GAO85741.1 - 5.7e-05 22.5 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Glyco_tranf_2_3 PF13641.1 GAO85743.1 - 3e-26 92.6 0.3 3.5e-26 92.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAO85743.1 - 1.2e-07 31.2 0.0 9.5e-07 28.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAO85743.1 - 4.1e-06 26.5 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ATP12 PF07542.6 GAO85744.1 - 1.1e-22 80.3 0.2 1.6e-20 73.2 0.0 2.4 2 0 0 2 2 2 2 ATP12 chaperone protein Oxysterol_BP PF01237.13 GAO85745.1 - 7.6e-133 442.3 0.0 6.1e-132 439.3 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 GAO85745.1 - 9.8e-17 61.0 0.0 7.4e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO85745.1 - 3.9e-16 58.7 0.6 1.3e-10 41.1 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAO85745.1 - 2.5e-14 52.2 0.0 0.0006 19.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAO85745.1 - 4.4e-13 49.3 0.1 3.3e-06 27.4 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO85745.1 - 5.5e-11 41.6 0.0 0.0035 17.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 GAO85745.1 - 1e-10 41.7 0.2 3.1e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAO85745.1 - 3.2e-07 30.3 0.8 7.5e-07 29.1 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.1 GAO85745.1 - 0.017 15.4 0.7 0.017 15.4 0.5 3.5 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-Mss51 PF13824.1 GAO85746.1 - 1.6e-28 98.3 6.4 3.4e-28 97.2 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 GAO85746.1 - 0.015 15.1 2.3 0.019 14.8 0.2 2.0 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.11 GAO85746.1 - 0.12 12.0 2.6 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 HIT zinc finger Malic_M PF03949.10 GAO85749.1 - 3.6e-83 279.0 0.0 4.9e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAO85749.1 - 5.7e-64 215.0 0.0 9.5e-64 214.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ADH_zinc_N PF00107.21 GAO85750.1 - 2.2e-30 104.8 1.5 2.8e-30 104.5 0.5 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO85750.1 - 2.5e-10 41.3 0.2 5.4e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO85750.1 - 2.4e-09 36.9 0.0 2.1e-08 33.8 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAO85750.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pep_deformylase PF01327.16 GAO85750.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase HupF_HypC PF01455.13 GAO85750.1 - 0.13 12.2 0.3 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 HupF/HypC family Clr5 PF14420.1 GAO85751.1 - 9.3e-13 47.8 1.4 1.6e-12 47.1 1.0 1.4 1 0 0 1 1 1 1 Clr5 domain Abhydrolase_5 PF12695.2 GAO85752.1 - 1.8e-07 30.9 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAO85752.1 - 1.7e-06 27.4 0.0 9.9e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAO85752.1 - 0.0001 21.5 0.1 0.00062 19.0 0.1 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAO85752.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 GAO85752.1 - 0.032 12.7 0.0 0.38 9.1 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 GAO85752.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase SNF2_N PF00176.18 GAO85753.1 - 1e-73 247.7 1.1 1.6e-73 247.1 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO85753.1 - 7e-15 54.6 0.1 2.2e-14 53.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO85753.1 - 1.1e-07 31.9 0.0 2.8e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAO85753.1 - 9e-06 25.2 0.0 6.1e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 GAO85753.1 - 3e-05 23.7 8.2 3e-05 23.7 5.7 2.2 2 0 0 2 2 2 1 HSA TM231 PF10149.4 GAO85753.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 DEAD_2 PF06733.10 GAO85753.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Membr_traf_MHD PF10540.4 GAO85754.1 - 7.5e-32 109.9 1.0 1.7e-31 108.8 0.1 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 GAO85754.1 - 1.3e-15 56.9 0.0 3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain NDUF_B8 PF05821.6 GAO85754.1 - 7.5e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Imm8 PF15560.1 GAO85754.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 8 Ribonuc_L-PSP PF01042.16 GAO85755.1 - 5.3e-42 142.3 0.0 5.9e-42 142.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pribosyltran PF00156.22 GAO85757.1 - 3.1e-17 62.4 0.0 4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAO85757.1 - 0.005 16.0 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AIG2_2 PF13772.1 GAO85758.1 - 0.0015 18.5 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family AIG2 PF06094.7 GAO85758.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 AIG2-like family Glyco_hydro_47 PF01532.15 GAO85759.1 - 9e-135 449.8 0.0 1.1e-134 449.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 GAO85759.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 PA domain WD40 PF00400.27 GAO85760.1 - 6.1e-59 193.9 9.5 5.9e-09 35.4 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAO85760.1 - 2.3e-05 23.3 1.7 0.011 14.4 0.2 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 GAO85760.1 - 0.032 12.3 0.4 4.6 5.2 0.0 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 TRAPP PF04051.11 GAO85761.1 - 3.9e-38 130.3 0.0 4.6e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 GAO85761.1 - 0.051 13.2 1.3 0.057 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) LisH PF08513.6 GAO85763.1 - 2.6e-05 23.8 0.2 4.9e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 LisH DND1_DSRM PF14709.1 GAO85764.1 - 0.76 10.1 9.2 1.1 9.5 0.0 4.0 5 0 0 5 5 5 0 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_1 PF00076.17 GAO85766.1 - 1.9e-46 155.5 0.0 8.4e-17 60.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85766.1 - 3.8e-28 97.2 0.0 2.1e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85766.1 - 2.8e-22 78.2 0.0 2.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAO85766.1 - 1e-05 25.2 0.0 0.0001 22.0 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 GAO85766.1 - 0.00013 21.6 0.1 0.009 15.7 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BTV_NS2 PF04514.7 GAO85767.1 - 0.015 14.1 1.6 0.023 13.5 1.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Bd3614_N PF14442.1 GAO85767.1 - 0.044 13.7 0.5 0.077 12.9 0.4 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal eIF-3c_N PF05470.7 GAO85767.1 - 0.062 11.3 0.4 0.12 10.3 0.1 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 GAO85767.1 - 0.08 12.5 6.2 0.35 10.4 3.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 GAO85767.1 - 0.27 10.9 9.6 0.03 14.0 3.8 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 GAO85767.1 - 0.61 9.5 7.9 3.7 7.0 6.2 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 GAO85767.1 - 1 7.9 13.9 0.2 10.3 7.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 GAO85767.1 - 2.4 8.4 15.1 1.9 8.7 9.1 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 GAO85767.1 - 2.6 7.1 6.0 4 6.5 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3295 PF11702.3 GAO85767.1 - 3.3 6.5 6.6 5.2 5.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ANAPC15 PF15243.1 GAO85767.1 - 6.6 6.8 14.2 0.93 9.5 6.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RRP7 PF12923.2 GAO85768.1 - 9e-33 113.0 9.6 9e-33 113.0 6.6 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Dak1_2 PF13684.1 GAO85768.1 - 0.00098 18.1 0.7 0.19 10.6 0.1 2.5 1 1 2 3 3 3 3 Dihydroxyacetone kinase family RRM_1 PF00076.17 GAO85768.1 - 0.0037 16.8 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 GAO85769.1 - 2.3e-125 416.6 0.0 2.9e-125 416.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 GAO85769.1 - 6e-11 41.9 0.0 7.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 GAO85769.1 - 7.4e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAO85769.1 - 1e-08 34.5 0.0 1.8e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 GAO85769.1 - 0.001 19.1 0.8 0.071 13.2 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain zf-CCHC PF00098.18 GAO85770.1 - 2.5e-41 137.7 55.9 2.4e-07 30.3 0.6 7.8 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.1 GAO85770.1 - 1.1e-06 28.1 38.7 0.069 12.8 0.4 6.9 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.1 GAO85770.1 - 1.1e-06 28.1 40.2 0.0058 16.3 0.2 7.0 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 GAO85770.1 - 0.073 12.5 0.3 0.073 12.5 0.2 7.1 4 2 3 7 7 7 0 Zinc knuckle UDPGP PF01704.13 GAO85771.1 - 2.6e-57 194.2 0.0 3.9e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 GAO85771.1 - 0.047 13.7 0.0 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 GAO85771.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pro_isomerase PF00160.16 GAO85772.1 - 1.2e-34 119.8 0.0 3.8e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 GAO85772.1 - 7.3e-16 57.5 0.0 1.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO85772.1 - 4e-12 45.9 0.0 9.6e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO85772.1 - 8.2e-10 38.3 0.0 4.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO85772.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_S24e PF01282.14 GAO85774.1 - 1.1e-35 121.2 0.2 1.9e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.4 GAO85775.1 - 9.1e-15 54.5 0.0 9.4e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 GAO85775.1 - 1.3e-05 24.6 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAO85775.1 - 2.6e-05 24.7 0.0 5.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85775.1 - 0.00035 20.1 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO85775.1 - 0.00038 20.2 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO85775.1 - 0.00039 19.6 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 GAO85775.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 GAO85775.1 - 0.0029 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 GAO85775.1 - 0.0066 15.5 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAO85775.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 GAO85775.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 GAO85775.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DivIVA PF05103.8 GAO85776.1 - 0.039 14.0 27.7 1.2 9.2 9.4 4.0 2 1 2 4 4 4 0 DivIVA protein DUF972 PF06156.8 GAO85776.1 - 3.7 7.9 21.0 2.3 8.6 1.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) CLTH PF10607.4 GAO85777.1 - 2.6e-34 118.0 0.0 4.4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 GAO85777.1 - 3.7e-20 72.2 0.2 6.2e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 GAO85777.1 - 5.3e-05 22.8 0.5 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 GAO85778.1 - 4.7e-92 307.9 25.7 5.5e-92 307.7 17.8 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DUF3166 PF11365.3 GAO85778.1 - 0.062 13.7 0.2 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) PAXIP1_C PF15364.1 GAO85778.1 - 0.39 10.6 2.8 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DnaJ PF00226.26 GAO85779.1 - 4e-13 48.8 0.0 8.1e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 GAO85780.1 - 1.5e-08 34.6 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Med19 PF10278.4 GAO85780.1 - 5.8 6.5 30.5 6.7 6.3 10.7 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Pyr_redox_2 PF07992.9 GAO85781.1 - 2.1e-28 99.5 0.4 3.3e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO85781.1 - 7e-16 58.4 1.2 2e-12 47.3 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 GAO85781.1 - 1.2e-13 50.4 0.0 3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 GAO85781.1 - 1.6e-09 38.1 0.0 0.00073 19.6 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 GAO85781.1 - 1.2e-05 25.4 0.0 4.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_7 PF13241.1 GAO85781.1 - 0.00037 20.6 0.3 0.097 12.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAO85781.1 - 0.0012 18.6 0.1 1.6 8.4 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAO85781.1 - 0.0038 16.1 0.0 1.9 7.3 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 GAO85781.1 - 0.0082 14.6 0.1 17 3.7 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein DUF1188 PF06690.6 GAO85781.1 - 0.017 14.2 0.1 0.038 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TrkA_N PF02254.13 GAO85781.1 - 0.021 14.7 1.2 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Arrestin_N PF00339.24 GAO85783.1 - 9.3e-15 54.7 1.1 9.4e-11 41.7 0.2 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 GAO85783.1 - 0.026 13.7 0.0 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Bul1 C terminus V-ATPase_G PF03179.10 GAO85785.1 - 8.1e-35 119.2 16.8 9.5e-35 119.0 11.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 GAO85785.1 - 0.017 14.9 11.7 0.017 14.9 8.1 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) MMR_HSR1_C PF08438.5 GAO85785.1 - 0.089 13.0 5.2 0.13 12.5 3.6 1.3 1 1 0 1 1 1 0 GTPase of unknown function C-terminal vATP-synt_E PF01991.13 GAO85785.1 - 0.17 11.1 17.3 1.1 8.5 7.4 2.2 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF2203 PF09969.4 GAO85785.1 - 0.22 11.7 4.6 0.31 11.2 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DDRGK PF09756.4 GAO85785.1 - 0.23 10.8 13.6 0.29 10.4 9.5 1.1 1 0 0 1 1 1 0 DDRGK domain Clathrin_lg_ch PF01086.12 GAO85785.1 - 0.25 11.2 12.0 0.3 10.9 8.3 1.0 1 0 0 1 1 1 0 Clathrin light chain HypD PF01924.11 GAO85785.1 - 0.3 9.7 2.1 0.34 9.5 1.4 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family OmpH PF03938.9 GAO85785.1 - 0.3 11.0 15.7 0.35 10.8 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2870 PF11069.3 GAO85785.1 - 0.38 10.8 6.5 0.54 10.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DAG_kinase_N PF14513.1 GAO85785.1 - 0.68 10.1 4.1 0.95 9.6 0.8 2.0 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus AIF-MLS PF14962.1 GAO85785.1 - 0.95 9.0 8.7 1.1 8.9 6.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF3552 PF12072.3 GAO85785.1 - 0.99 8.5 22.0 0.054 12.6 9.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ECM11 PF15463.1 GAO85785.1 - 1.5 9.1 10.3 3.3 8.0 7.1 1.6 1 1 0 1 1 1 0 Extracellular mutant protein 11 NPR3 PF03666.8 GAO85785.1 - 1.7 7.0 5.2 2 6.8 3.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3072 PF11272.3 GAO85785.1 - 1.8 8.2 5.5 0.34 10.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) CAF-1_p150 PF11600.3 GAO85785.1 - 2 7.7 19.2 2.3 7.5 13.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRF PF01765.14 GAO85785.1 - 3.3 7.1 14.4 5.7 6.3 10.0 1.5 1 1 0 1 1 1 0 Ribosome recycling factor Colicin-DNase PF12639.2 GAO85785.1 - 3.4 7.9 6.6 5.9 7.1 4.6 1.5 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Muted PF14942.1 GAO85785.1 - 4.1 7.2 11.6 3 7.6 6.7 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein SAPS PF04499.10 GAO85785.1 - 6.1 5.3 8.1 5.7 5.4 5.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HrpE PF06188.7 GAO85785.1 - 6.5 6.4 11.4 4.5 6.9 4.8 1.9 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF2151 PF10221.4 GAO85785.1 - 7.7 4.5 8.6 8.2 4.4 6.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF883 PF05957.8 GAO85785.1 - 7.9 6.9 10.7 84 3.6 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 GAO85785.1 - 10 6.6 16.8 0.4 11.1 5.0 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term IDO PF01231.13 GAO85786.1 - 2.7e-40 138.0 0.0 4.1e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase LRR_4 PF12799.2 GAO85787.1 - 2.1e-11 43.1 1.8 0.04 13.5 0.0 6.9 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) TPR_11 PF13414.1 GAO85787.1 - 5.1e-08 32.4 5.8 4.1e-05 23.1 2.6 2.6 1 1 0 2 2 2 2 TPR repeat LRR_6 PF13516.1 GAO85787.1 - 6e-07 28.8 0.9 3.3 8.0 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich repeat TPR_2 PF07719.12 GAO85787.1 - 1.4e-06 27.7 4.7 0.44 10.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 GAO85787.1 - 2.5e-06 27.0 0.7 1e-05 25.0 0.2 2.4 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 GAO85787.1 - 2.1e-05 24.1 9.4 1.2 8.9 0.0 6.3 5 2 2 7 7 7 2 Leucine rich repeat TPR_1 PF00515.23 GAO85787.1 - 0.00012 21.5 6.2 0.81 9.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat LRR_7 PF13504.1 GAO85787.1 - 0.00013 21.6 0.5 7.5 7.2 0.0 6.6 9 0 0 9 9 6 1 Leucine rich repeat TPR_16 PF13432.1 GAO85787.1 - 0.00028 21.4 4.8 0.056 14.1 1.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.2 GAO85787.1 - 0.0011 18.7 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.1 GAO85787.1 - 0.0012 18.7 6.8 0.0044 16.9 1.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat LRR_1 PF00560.28 GAO85787.1 - 0.0013 18.5 3.2 21 5.6 0.0 6.2 5 2 1 6 6 5 0 Leucine Rich Repeat TPR_19 PF14559.1 GAO85787.1 - 0.0098 16.2 3.3 2.4 8.5 2.3 2.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85787.1 - 0.023 15.3 4.9 2.2 9.1 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85787.1 - 0.036 13.8 0.6 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.3 GAO85788.1 - 2.2e-45 154.2 11.5 2.2e-45 154.2 8.0 3.2 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 GAO85788.1 - 0.00077 18.2 5.1 0.0022 16.7 3.5 1.8 1 0 0 1 1 1 1 Spc7 kinetochore protein Bacillus_HBL PF05791.6 GAO85788.1 - 0.11 11.8 4.1 0.37 10.1 2.8 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 GAO85788.1 - 0.15 11.9 7.7 0.61 10.0 0.1 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF465 PF04325.8 GAO85788.1 - 0.28 10.9 12.5 0.25 11.0 1.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF465) ADH_N PF08240.7 GAO85789.1 - 1.3e-23 82.8 0.6 2.1e-23 82.1 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO85789.1 - 5.7e-20 71.1 0.0 8.4e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO85789.1 - 2.3e-08 34.9 0.0 4.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO85789.1 - 0.0062 15.7 0.3 0.01 14.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAO85789.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RTA1 PF04479.8 GAO85790.1 - 7.4e-54 182.6 10.1 7.4e-54 182.6 7.0 1.8 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.13 GAO85791.1 - 0.00011 21.9 3.4 0.0002 21.1 2.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO85791.1 - 0.00012 20.7 0.0 0.00018 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.8 GAO85793.1 - 2.2e-23 82.3 0.0 7.8e-10 37.5 0.0 3.9 3 1 0 3 3 3 3 Nup85 Nucleoporin RNA_pol_Rpb2_6 PF00562.23 GAO85796.1 - 2.4e-124 414.9 0.1 4.7e-124 414.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAO85796.1 - 1.1e-61 207.3 0.0 1.7e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAO85796.1 - 2.2e-46 157.6 0.0 4e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAO85796.1 - 2.9e-30 104.3 0.0 7e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 GAO85796.1 - 5.6e-25 86.9 0.9 1.3e-24 85.7 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 GAO85796.1 - 1e-23 83.0 0.4 2.9e-23 81.5 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 GAO85796.1 - 2.9e-23 81.3 0.4 9.8e-23 79.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 CTNNBL PF08216.6 GAO85797.1 - 5.6e-35 119.2 0.3 9.1e-33 112.0 0.0 3.3 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.8 GAO85797.1 - 0.0037 16.6 0.2 0.017 14.5 0.1 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain HEAT_2 PF13646.1 GAO85797.1 - 0.027 14.7 5.1 1.5 9.1 0.3 3.9 2 1 1 3 3 3 0 HEAT repeats Mo25 PF08569.6 GAO85797.1 - 0.037 13.0 0.7 0.086 11.8 0.5 1.6 1 0 0 1 1 1 0 Mo25-like CMAS PF02353.15 GAO85797.1 - 0.051 12.6 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Arm PF00514.18 GAO85797.1 - 0.084 12.7 0.1 5.9 6.8 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CDC37_N PF03234.9 GAO85797.1 - 0.35 11.1 5.3 0.59 10.4 0.1 3.1 2 2 0 2 2 2 0 Cdc37 N terminal kinase binding Fungal_trans PF04082.13 GAO85798.1 - 3e-27 95.1 3.7 4.9e-27 94.4 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAPRTase PF04095.11 GAO85799.1 - 2.2e-52 177.8 0.1 2.8e-28 98.8 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family ING PF12998.2 GAO85800.1 - 6.6e-26 90.6 6.2 1.5e-25 89.5 4.3 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAO85800.1 - 1.3e-08 34.3 9.5 2.3e-08 33.5 6.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 GAO85800.1 - 0.013 15.6 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Nucleoplasmin PF03066.10 GAO85800.1 - 0.024 14.1 2.0 0.046 13.2 1.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4200 PF13863.1 GAO85800.1 - 0.12 12.3 8.5 0.74 9.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) TPR_11 PF13414.1 GAO85801.1 - 5.6e-59 195.6 21.0 2.7e-19 68.5 0.7 6.5 3 3 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAO85801.1 - 9.5e-47 154.7 23.0 1.9e-07 30.4 0.1 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 GAO85801.1 - 1.5e-37 124.4 29.4 3.8e-05 23.2 0.1 10.1 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 GAO85801.1 - 1.3e-24 85.9 12.7 5.4e-11 42.2 0.3 5.6 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAO85801.1 - 1.6e-20 73.2 12.5 0.00051 20.6 0.0 6.8 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAO85801.1 - 4.6e-16 57.8 16.8 0.057 14.0 0.0 9.8 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO85801.1 - 3.5e-15 54.5 19.2 0.00013 21.4 0.2 7.9 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAO85801.1 - 5.7e-15 55.4 11.0 0.0071 16.6 0.1 6.9 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAO85801.1 - 1.7e-12 46.1 14.9 8.3e-06 25.2 0.1 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO85801.1 - 1.8e-12 46.4 8.4 0.0017 18.4 0.0 7.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAO85801.1 - 1.2e-08 34.6 9.3 0.011 15.5 0.1 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAO85801.1 - 7.9e-07 28.8 2.4 3.4 7.6 0.0 6.2 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 GAO85801.1 - 0.00013 22.0 14.7 0.01 15.9 0.9 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAO85801.1 - 0.00065 19.9 19.1 0.036 14.5 0.1 7.9 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAO85801.1 - 0.0031 17.3 5.3 24 5.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 GAO85801.1 - 0.0062 15.3 0.1 0.0062 15.3 0.1 4.4 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 GAO85801.1 - 0.01 15.9 0.1 0.01 15.9 0.0 4.8 5 2 1 6 6 4 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 GAO85801.1 - 0.011 16.2 0.2 0.049 14.2 0.0 2.3 2 0 0 2 2 1 0 Peptidase inhibitor I9 MIT PF04212.13 GAO85801.1 - 0.041 13.7 22.9 1.6 8.6 2.3 6.6 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 GAO85801.1 - 0.076 12.2 8.0 19 4.6 0.1 5.5 6 0 0 6 6 6 0 SHNi-TPR TPR_3 PF07720.7 GAO85801.1 - 1.5 8.6 21.1 1.8 8.4 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.7 GAO85802.1 - 1.7e-115 385.6 0.0 3.6e-115 384.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit C2 PF00168.25 GAO85802.1 - 1.3e-61 204.4 0.2 1.5e-19 69.5 0.0 5.6 5 0 0 5 5 5 5 C2 domain B56 PF01603.15 GAO85802.1 - 0.061 11.9 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) UDPGP PF01704.13 GAO85803.1 - 4.7e-184 611.7 0.3 5.4e-184 611.5 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 GAO85803.1 - 0.014 15.3 0.1 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO Fungal_trans PF04082.13 GAO85804.1 - 1.7e-11 43.4 0.1 2.8e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85804.1 - 3.8e-06 26.6 8.6 8.6e-06 25.5 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO85805.1 - 8.1e-17 60.9 2.7 1e-16 60.6 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85805.1 - 9.4e-11 41.4 11.5 2e-10 40.4 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 GAO85806.1 - 8.3e-06 24.9 29.1 0.042 13.5 2.7 4.3 3 0 0 3 3 3 3 AT hook motif SLAC1 PF03595.12 GAO85807.1 - 5.5e-105 350.6 53.0 5.5e-105 350.6 36.7 3.8 3 1 1 4 4 4 1 Voltage-dependent anion channel Sugar_tr PF00083.19 GAO85807.1 - 7.3e-18 64.3 17.0 7.3e-18 64.3 11.8 4.1 3 2 0 4 4 4 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85807.1 - 5.3e-14 51.7 95.1 5.5e-14 51.6 16.5 4.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF218 PF02698.12 GAO85808.1 - 5.8e-14 51.8 0.0 8.1e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain F-box-like PF12937.2 GAO85809.1 - 0.0003 20.4 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2989 PF11207.3 GAO85809.1 - 0.13 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Polysacc_deac_1 PF01522.16 GAO85810.1 - 1.1e-10 41.2 0.1 1.3e-09 37.7 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 GAO85810.1 - 4.3e-07 29.8 19.8 8.4e-07 28.8 13.7 1.5 1 0 0 1 1 1 1 Chitin recognition protein Fringe PF02434.11 GAO85810.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Fringe-like PIG-L PF02585.12 GAO85811.1 - 1.3e-17 64.5 0.1 3.4e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Chlorosome_CsmC PF11098.3 GAO85812.1 - 1.5 8.5 8.3 2.1 8.0 5.7 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Ank_2 PF12796.2 GAO85813.1 - 1.5e-18 66.9 0.1 5.3e-10 39.5 0.0 4.0 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO85813.1 - 7.5e-15 53.9 0.8 9.9e-07 28.2 0.0 6.3 6 2 1 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 GAO85813.1 - 3.4e-14 51.5 0.7 0.00038 20.4 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 GAO85813.1 - 6.9e-14 51.9 0.1 1.9e-05 25.0 0.0 6.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO85813.1 - 1.4e-07 31.5 1.8 0.0022 18.1 0.0 4.8 5 1 1 6 6 6 1 Ankyrin repeats (many copies) DUF1707 PF08044.6 GAO85813.1 - 0.09 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) PSDC PF12588.3 GAO85814.1 - 3.7e-54 182.1 0.0 5.4e-54 181.6 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 GAO85814.1 - 1.8e-34 118.8 0.0 4.8e-34 117.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 GAO85814.1 - 0.002 17.7 0.7 2.3 7.9 0.1 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like HMGL-like PF00682.14 GAO85815.1 - 2.2e-40 138.8 0.0 2.7e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 HMGL-like COesterase PF00135.23 GAO85816.1 - 1.3e-94 317.8 0.0 1.9e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO85816.1 - 1.9e-11 43.9 0.1 4.5e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO85816.1 - 6.3e-08 32.0 0.1 1.1e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.5 GAO85816.1 - 0.012 14.5 0.0 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 GAO85816.1 - 0.03 14.0 0.2 0.055 13.2 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Amidase PF01425.16 GAO85818.1 - 5.9e-85 285.7 0.0 8.7e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 GAO85819.1 - 4.3e-07 28.8 0.1 0.00018 20.2 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO85820.1 - 1.7e-11 43.4 18.8 7.5e-11 41.3 13.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 GAO85821.1 - 1.3e-07 30.5 2.3 2.1e-07 29.9 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain HEAT_2 PF13646.1 GAO85821.1 - 0.02 15.1 0.1 0.095 12.9 0.0 2.0 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 GAO85821.1 - 0.052 13.6 0.1 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat FYVE PF01363.16 GAO85822.1 - 3.9e-21 74.7 0.8 3.9e-21 74.7 0.5 3.5 4 0 0 4 4 4 1 FYVE zinc finger Zn_clus PF00172.13 GAO85822.1 - 8.5e-05 22.3 11.5 8.5e-05 22.3 8.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 GAO85823.1 - 1.1e-97 327.4 24.0 4.7e-97 325.3 16.6 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAO85823.1 - 5.7e-30 104.2 0.1 8.5e-30 103.6 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Cys_Met_Meta_PP PF01053.15 GAO85824.1 - 9.4e-59 198.6 0.0 1.9e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ThiS PF02597.15 GAO85824.1 - 3.1e-05 24.3 0.0 7.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ThiS family Aminotran_1_2 PF00155.16 GAO85824.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II MARVEL PF01284.18 GAO85825.1 - 5.3e-06 26.3 14.6 7.2e-06 25.8 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2207 PF09972.4 GAO85825.1 - 0.00064 18.4 0.4 0.00064 18.4 0.3 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) RDD PF06271.7 GAO85825.1 - 0.035 14.0 7.8 0.069 13.0 0.2 2.3 2 1 0 2 2 2 0 RDD family UPF0104 PF03706.8 GAO85825.1 - 0.076 12.2 7.0 0.23 10.7 4.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) CytB6-F_Fe-S PF08802.5 GAO85825.1 - 0.15 12.0 0.5 0.15 12.0 0.3 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DUF2189 PF09955.4 GAO85825.1 - 5.7 6.9 15.1 0.48 10.3 2.7 2.9 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) FAD_binding_4 PF01565.18 GAO85826.1 - 2.2e-17 62.8 0.2 1.2e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain RNB PF00773.14 GAO85827.1 - 2.3e-52 178.2 0.0 8e-51 173.2 0.0 2.4 1 1 0 1 1 1 1 RNB domain Glyco_hydro_7 PF00840.15 GAO85828.1 - 2.3e-141 471.1 11.7 3.1e-141 470.6 8.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 AMP-binding PF00501.23 GAO85829.1 - 8.9e-68 228.5 0.0 1.2e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO85829.1 - 2.1e-12 47.8 0.0 4.8e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Adenylsucc_synt PF00709.16 GAO85829.1 - 0.092 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase BolA PF01722.13 GAO85830.1 - 1.6e-29 101.6 1.5 1.9e-29 101.3 1.0 1.1 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.14 GAO85831.1 - 1.5e-09 37.4 6.5 1.5e-09 37.4 4.5 2.7 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.20 GAO85831.1 - 0.00051 20.1 1.7 0.00051 20.1 1.2 2.6 1 1 0 2 2 2 1 Syntaxin Dispanin PF04505.7 GAO85831.1 - 0.0022 17.5 0.4 0.0046 16.4 0.3 1.5 1 0 0 1 1 1 1 Interferon-induced transmembrane protein MCPsignal PF00015.16 GAO85831.1 - 0.0091 15.5 10.9 0.0098 15.4 5.5 2.0 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Corona_S2 PF01601.11 GAO85831.1 - 0.041 11.9 0.3 0.073 11.1 0.2 1.4 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein Tweety PF04906.8 GAO85831.1 - 0.043 12.2 3.5 0.051 11.9 1.0 1.9 1 1 1 2 2 2 0 Tweety PBP1_TM PF14812.1 GAO85831.1 - 0.055 13.7 0.2 0.055 13.7 0.1 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bac_export_3 PF01313.14 GAO85831.1 - 0.059 13.0 0.2 0.095 12.3 0.2 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 DUF724 PF05266.9 GAO85831.1 - 0.11 12.1 6.2 1.5 8.4 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin_2 PF14523.1 GAO85831.1 - 0.12 12.4 10.9 0.058 13.4 1.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein VitD-bind_III PF09164.5 GAO85831.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COG2 PF06148.6 GAO85831.1 - 0.16 11.8 4.1 2.7 7.8 0.1 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HisKA_3 PF07730.8 GAO85831.1 - 0.17 12.2 7.4 1.4 9.3 0.0 3.6 3 1 1 4 4 4 0 Histidine kinase Spectrin PF00435.16 GAO85831.1 - 0.28 11.4 13.5 3.1 8.1 0.1 2.9 2 1 1 3 3 3 0 Spectrin repeat Complex1_LYR PF05347.10 GAO85831.1 - 0.38 10.5 4.8 2.1 8.1 0.9 3.0 3 0 0 3 3 3 0 Complex 1 protein (LYR family) NPV_P10 PF05531.7 GAO85831.1 - 0.39 10.9 2.8 6.8 7.0 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Synaptobrevin PF00957.16 GAO85831.1 - 1.1 8.9 6.6 0.19 11.3 1.3 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF2458 PF10454.4 GAO85831.1 - 2.6 7.9 10.6 0.21 11.4 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) DUF2562 PF10814.3 GAO85831.1 - 5.8 6.8 7.0 0.48 10.3 0.7 2.1 2 1 0 3 3 2 0 Protein of unknown function (DUF2562) Laminin_II PF06009.7 GAO85831.1 - 6.2 6.5 9.5 2 8.1 2.6 2.4 2 1 0 2 2 2 0 Laminin Domain II PTR2 PF00854.16 GAO85832.1 - 1e-52 179.2 9.2 3.7e-52 177.3 6.4 1.8 1 1 0 1 1 1 1 POT family UPF0233 PF06781.7 GAO85832.1 - 8 6.1 6.9 3.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) IF4E PF01652.13 GAO85833.1 - 5.3e-60 201.7 0.1 6.9e-60 201.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 GAO85834.1 - 2.2e-24 84.8 0.6 3.7e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 GAO85835.1 - 1.8e-28 98.0 2.7 4.3e-28 96.8 1.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 GAO85835.1 - 5.9e-21 73.5 0.0 1.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.17 GAO85836.1 - 2.9e-39 134.8 0.0 6.9e-39 133.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Bac_rhodopsin PF01036.13 GAO85837.1 - 2.1e-35 122.0 16.0 2.5e-35 121.7 11.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF805 PF05656.9 GAO85837.1 - 6.1 6.6 8.2 24 4.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) tRNA-synt_1 PF00133.17 GAO85838.1 - 3e-164 547.3 0.0 4e-164 546.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAO85838.1 - 3e-22 79.0 0.2 4.9e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAO85838.1 - 3.2e-22 78.7 0.0 1.9e-12 46.5 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 GAO85838.1 - 3.1e-05 23.4 3.1 6.2e-05 22.5 2.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 GAO85838.1 - 0.011 14.8 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 GAO85838.1 - 0.094 11.5 0.0 0.46 9.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1_2 PF13603.1 GAO85838.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Zwint PF15556.1 GAO85838.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 ZW10 interactor UPF0183 PF03676.9 GAO85839.1 - 2.6e-19 69.0 0.0 1.6e-08 33.5 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 GAO85840.1 - 8.8e-112 373.1 1.0 8.8e-112 373.1 0.7 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 GAO85840.1 - 2e-11 44.2 0.1 2e-11 44.2 0.1 4.7 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding ATP-synt_B PF00430.13 GAO85840.1 - 0.39 10.5 22.8 0.074 12.8 5.0 4.6 4 0 0 4 4 4 0 ATP synthase B/B' CF(0) Baculo_PEP_C PF04513.7 GAO85840.1 - 1.5 8.6 21.0 0.23 11.2 0.1 5.2 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rhodanese PF00581.15 GAO85842.1 - 9.2e-20 71.0 0.0 1.9e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 GAO85843.1 - 0.0035 17.4 0.1 0.67 10.0 0.0 2.5 1 1 0 1 1 1 1 PIN domain RPEL PF02755.10 GAO85844.1 - 3.4e-31 105.7 17.4 6.5e-12 44.3 1.4 3.4 3 0 0 3 3 3 3 RPEL repeat CP12 PF02672.10 GAO85844.1 - 0.00079 19.8 0.3 0.3 11.5 0.1 2.4 2 0 0 2 2 2 2 CP12 domain DUF4174 PF13778.1 GAO85844.1 - 0.24 11.4 1.5 0.95 9.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) Translin PF01997.11 GAO85845.1 - 2.2e-77 259.1 0.0 3.4e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 Translin family Glyco_hydro_2_N PF02837.13 GAO85845.1 - 2e-11 43.7 0.0 1.7e-10 40.6 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAO85845.1 - 2.6e-11 43.9 0.0 6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAO85845.1 - 0.00082 18.3 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 GAO85846.1 - 1.6e-23 82.8 0.7 3.4e-23 81.8 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85846.1 - 3.2e-06 26.9 14.2 6e-06 26.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans PF05007.8 GAO85847.1 - 4e-77 259.3 9.1 9.2e-77 258.1 6.3 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 GAO85847.1 - 3.2e-12 46.0 2.4 3.2e-12 46.0 1.7 2.0 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U DUF2029 PF09594.5 GAO85847.1 - 6.6e-05 22.5 34.3 0.0014 18.1 23.6 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2029) IMS PF00817.15 GAO85850.1 - 5.3e-43 146.3 1.7 6.5e-43 146.0 0.3 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 GAO85850.1 - 3.9e-14 52.6 0.2 1.2e-13 51.0 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAO85850.1 - 8.5e-07 28.6 0.0 2.9e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif His_Phos_2 PF00328.17 GAO85853.1 - 4.3e-33 115.0 0.0 5.6e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DnaJ-X PF14308.1 GAO85854.1 - 4.3e-74 248.2 4.3 4.3e-74 248.2 3.0 3.2 3 2 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAO85854.1 - 3.7e-25 87.4 0.1 1.2e-24 85.7 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Med3 PF11593.3 GAO85854.1 - 0.39 9.9 3.5 0.58 9.3 2.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DEC-1_N PF04625.8 GAO85854.1 - 4.8 5.7 10.1 8.2 4.9 7.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SQS_PSY PF00494.14 GAO85855.1 - 2e-39 135.4 0.0 2.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase NPL4 PF05021.10 GAO85855.1 - 0.089 11.9 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NPL4 family Hemerythrin PF01814.18 GAO85856.1 - 1.6e-13 50.9 0.5 1.9e-13 50.6 0.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_9 PF13371.1 GAO85856.1 - 0.0042 16.8 0.1 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat OsmC PF02566.14 GAO85856.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 OsmC-like protein Peptidase_A4 PF01828.12 GAO85857.1 - 8.9e-88 292.7 9.4 1.1e-87 292.5 6.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family MFS_1 PF07690.11 GAO85858.1 - 8.8e-26 90.4 34.2 3.6e-18 65.3 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.3 GAO85858.1 - 0.0088 15.8 3.0 0.0088 15.8 2.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3522) COesterase PF00135.23 GAO85859.1 - 6.9e-71 239.5 0.0 9.7e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO85859.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SRR1 PF07985.7 GAO85860.1 - 0.00042 20.1 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 SRR1 Adaptin_N PF01602.15 GAO85862.1 - 0.037 12.3 2.1 0.06 11.6 0.9 1.8 2 0 0 2 2 2 0 Adaptin N terminal region SKG6 PF08693.5 GAO85863.1 - 0.07 12.4 0.4 0.17 11.2 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Hamartin PF04388.7 GAO85863.1 - 0.36 9.4 2.8 0.47 9.0 1.9 1.0 1 0 0 1 1 1 0 Hamartin protein Glyco_transf_34 PF05637.7 GAO85864.1 - 6.8e-15 55.2 0.0 1.3e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 GAO85864.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 TauD PF02668.11 GAO85865.1 - 1.3e-52 179.0 0.4 1.6e-52 178.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 GAO85865.1 - 0.047 14.2 0.1 7.2 7.2 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily ATG2_CAD PF13329.1 GAO85865.1 - 0.18 11.4 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif AA_permease PF00324.16 GAO85866.1 - 5.7e-108 361.3 42.8 2.2e-107 359.3 30.2 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 GAO85866.1 - 1.5e-31 109.4 45.6 2e-31 108.9 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease Cellulase PF00150.13 GAO85867.1 - 5.5e-20 71.7 1.9 7.4e-20 71.2 1.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 GAO85867.1 - 3.7e-08 32.6 0.1 2.1e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 GAO85867.1 - 1.6e-05 24.2 0.5 7.5e-05 22.0 0.4 1.8 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 GAO85867.1 - 0.091 13.2 0.0 0.3 11.5 0.0 2.0 1 1 0 1 1 1 0 Sugar-binding cellulase-like Ank_2 PF12796.2 GAO85869.1 - 2.2e-60 200.9 27.9 5.9e-21 74.5 2.7 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO85869.1 - 6e-45 148.8 25.5 6.5e-09 35.1 0.1 9.3 9 1 1 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 GAO85869.1 - 3.7e-34 116.4 10.0 3e-09 37.1 0.2 6.9 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO85869.1 - 1.5e-31 107.6 19.4 1.5e-12 47.3 0.7 5.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO85869.1 - 2.9e-23 79.6 16.9 9.5e-06 25.3 0.1 8.7 8 1 1 9 9 9 6 Ankyrin repeat SH3_3 PF08239.6 GAO85869.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain FAD_binding_3 PF01494.14 GAO85870.1 - 4e-19 68.8 0.3 1.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO85870.1 - 0.00034 20.5 0.0 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 GAO85870.1 - 0.0053 15.6 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase ApbA PF02558.11 GAO85870.1 - 0.0074 15.7 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAO85870.1 - 0.033 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO85870.1 - 0.05 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_7 PF03492.10 GAO85870.1 - 0.11 11.2 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase dCMP_cyt_deam_1 PF00383.17 GAO85871.1 - 1.7e-07 30.8 0.1 2.1e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Fer2_4 PF13510.1 GAO85871.1 - 0.034 13.9 0.4 0.072 12.9 0.2 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ATP-grasp_4 PF13535.1 GAO85872.1 - 2.9e-08 33.6 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Methyltransf_31 PF13847.1 GAO85872.1 - 2.5e-06 27.1 0.2 5.4e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85872.1 - 6.3e-06 26.7 0.1 2.6e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO85872.1 - 1e-05 25.7 0.7 1.9e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85872.1 - 7.7e-05 23.1 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO85872.1 - 0.00016 21.6 0.2 0.00054 19.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAO85872.1 - 0.00068 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAO85872.1 - 0.0029 18.0 0.1 0.009 16.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO85872.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ATP-grasp_3 PF02655.9 GAO85872.1 - 0.0071 16.2 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Methyltransf_23 PF13489.1 GAO85872.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAO85872.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase FmrO PF07091.6 GAO85872.1 - 0.14 11.1 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) OPT PF03169.10 GAO85873.1 - 3.8e-148 494.7 45.1 4.3e-148 494.5 31.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.2 GAO85874.1 - 0.00035 20.2 0.3 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 GAO85874.1 - 0.0049 16.6 1.4 0.017 14.8 1.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat CDC45 PF02724.9 GAO85874.1 - 0.037 12.0 3.6 0.052 11.5 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 GAO85874.1 - 0.091 11.4 7.8 0.12 11.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 GAO85874.1 - 0.28 9.2 2.5 0.38 8.7 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 GAO85874.1 - 0.35 8.6 2.3 0.45 8.3 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 GAO85874.1 - 4.3 7.0 7.5 7.3 6.3 5.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit VID27 PF08553.5 GAO85874.1 - 4.6 5.3 9.6 6.5 4.8 6.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAD_binding_4 PF01565.18 GAO85877.1 - 6.4e-17 61.3 0.1 1.4e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO85877.1 - 5.5e-09 35.8 0.1 1.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAO85877.1 - 0.022 13.9 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Cutinase PF01083.17 GAO85879.1 - 3.4e-23 82.2 0.0 5.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cutinase SUR7 PF06687.7 GAO85879.1 - 1.5e-15 57.3 2.5 2.3e-15 56.7 1.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Thioesterase PF00975.15 GAO85879.1 - 1.9e-05 25.0 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 GAO85879.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 GAO85879.1 - 0.0043 16.6 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO85879.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85879.1 - 0.04 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 GAO85879.1 - 0.087 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Flu_NS2 PF00601.14 GAO85879.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Amastin PF07344.6 GAO85879.1 - 0.27 10.8 9.2 0.63 9.6 6.3 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein Sugar_tr PF00083.19 GAO85880.1 - 9.9e-146 485.8 31.3 1.1e-145 485.6 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO85880.1 - 1.5e-24 86.3 43.2 7.2e-21 74.2 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO85880.1 - 0.0039 15.6 3.9 0.0039 15.6 2.7 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein DUF605 PF04652.11 GAO85881.1 - 3.1 7.1 9.0 3.9 6.7 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Grp1_Fun34_YaaH PF01184.14 GAO85882.1 - 2.1e-26 92.5 19.3 2.8e-26 92.1 13.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aldedh PF00171.17 GAO85883.1 - 3.6e-187 622.3 0.2 4.1e-187 622.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAO85883.1 - 0.066 12.4 0.2 0.72 9.0 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) ADH_N PF08240.7 GAO85884.1 - 4.2e-30 103.7 0.2 7.8e-30 102.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO85884.1 - 3.2e-24 84.9 0.4 3.2e-24 84.9 0.3 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO85884.1 - 0.0001 23.1 0.1 0.00019 22.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO85884.1 - 0.0094 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO85884.1 - 0.061 12.8 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mannosyl_trans3 PF11051.3 GAO85885.1 - 1.8e-28 99.6 0.0 9.5e-28 97.2 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative Cupin_2 PF07883.6 GAO85886.1 - 3.2e-07 29.7 0.4 5.2e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_3 PF01494.14 GAO85887.1 - 6.5e-72 242.5 0.1 2.5e-49 168.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 GAO85887.1 - 2.3e-39 134.7 0.0 3.8e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAO85887.1 - 8.9e-05 21.6 0.1 0.00014 20.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAO85887.1 - 0.0014 17.5 2.2 0.0023 16.9 0.9 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO85887.1 - 0.0025 17.7 0.3 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO85887.1 - 0.0064 15.3 0.1 0.0097 14.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAO85887.1 - 0.0071 14.8 0.1 0.014 13.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAO85887.1 - 0.012 15.9 0.4 0.45 10.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO85887.1 - 0.016 14.0 0.0 0.035 12.9 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.2 GAO85887.1 - 0.016 14.2 0.2 0.03 13.4 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO85887.1 - 0.033 14.0 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO85887.1 - 0.098 11.4 1.1 0.94 8.2 0.8 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO85887.1 - 0.14 11.0 0.2 0.31 9.9 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein MutS_I PF01624.15 GAO85887.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 MutS domain I Sulfotransfer_1 PF00685.22 GAO85888.1 - 3.1e-59 200.4 1.7 2.5e-58 197.4 1.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 GAO85888.1 - 7.2e-07 30.2 2.3 7.4e-06 26.9 1.6 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 GAO85889.1 - 1.3e-05 26.2 0.3 2.6e-05 25.1 0.1 1.6 1 1 1 2 2 2 1 Sulfotransferase family Peroxidase_2 PF01328.12 GAO85890.1 - 0.027 13.1 0.1 0.04 12.5 0.1 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 RNase_T PF00929.19 GAO85891.1 - 1.4e-20 74.2 0.1 2.8e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAO85891.1 - 0.0021 17.5 0.8 0.0085 15.5 0.3 2.1 2 1 0 2 2 2 1 3'-5' exonuclease Lipoxygenase PF00305.14 GAO85892.1 - 2.2e-43 148.2 0.5 4e-38 130.8 0.5 2.9 2 1 0 2 2 2 2 Lipoxygenase Acetyltransf_3 PF13302.1 GAO85893.1 - 1.7e-14 54.1 0.0 3.5e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAO85893.1 - 7.4e-08 32.4 0.0 9.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO85893.1 - 3.1e-07 30.3 0.0 6.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family adh_short PF00106.20 GAO85894.1 - 2.8e-23 82.6 0.4 9.1e-23 80.9 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO85894.1 - 2.9e-13 49.8 0.2 3.7e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO85894.1 - 1.8e-05 24.3 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAO85894.1 - 0.00057 18.8 0.0 0.00076 18.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 GAO85894.1 - 0.0013 17.7 0.1 0.0017 17.3 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 GAO85894.1 - 0.0066 16.4 0.5 0.022 14.7 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 GAO85895.1 - 1.4e-33 116.6 0.1 1.7e-33 116.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO85895.1 - 1.6e-19 70.0 0.0 4.3e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO85895.1 - 9.9e-16 57.9 0.1 4.6e-14 52.5 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 GAO85895.1 - 2.9e-06 25.9 0.0 4.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 GAO85895.1 - 0.00015 21.5 0.0 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein BAAT_C PF08840.6 GAO85895.1 - 0.00041 20.1 0.0 0.0014 18.3 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAO85895.1 - 0.00059 19.1 0.0 0.0022 17.2 0.0 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAO85895.1 - 0.0047 16.4 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 GAO85895.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 Secretory lipase Hydrolase_4 PF12146.3 GAO85895.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase adh_short PF00106.20 GAO85896.1 - 7.2e-22 78.0 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO85896.1 - 5.6e-09 35.9 0.1 1e-08 35.0 0.0 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAO85896.1 - 0.00047 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAO85896.1 - 0.00092 19.3 0.1 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 GAO85897.1 - 3.2e-39 134.5 0.0 4.1e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO85897.1 - 1.1e-20 74.4 0.0 1.4e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO85897.1 - 6.4e-11 42.1 0.2 2.7e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO85897.1 - 9.3e-05 21.2 0.1 0.00017 20.4 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO85897.1 - 0.0019 17.2 0.3 0.15 10.9 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 GAO85897.1 - 0.025 14.4 2.4 0.039 13.8 1.2 1.7 1 1 1 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.13 GAO85897.1 - 0.03 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 GAO85897.1 - 0.032 14.6 0.2 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.10 GAO85897.1 - 0.12 11.9 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus GFA PF04828.9 GAO85898.1 - 9.8e-23 79.9 0.4 1.5e-22 79.3 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 GAO85898.1 - 0.033 13.6 2.3 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.7 GAO85898.1 - 0.07 12.9 0.1 0.07 12.9 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RNA_POL_M_15KD PF02150.11 GAO85898.1 - 0.11 12.1 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CorA PF01544.13 GAO85899.1 - 0.22 10.5 3.1 0.42 9.6 1.4 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 GAO85900.1 - 8.7e-05 22.1 35.1 0.052 13.1 3.4 3.1 1 1 2 3 3 3 3 IncA protein DUF869 PF05911.6 GAO85900.1 - 0.00054 18.3 26.5 0.0093 14.2 14.9 2.0 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) Rootletin PF15035.1 GAO85900.1 - 0.00065 19.7 18.9 0.00065 19.7 13.1 3.2 1 1 1 3 3 3 2 Ciliary rootlet component, centrosome cohesion DUF2968 PF11180.3 GAO85900.1 - 0.0069 15.7 7.5 0.0069 15.7 5.2 3.6 2 1 2 4 4 4 2 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 GAO85900.1 - 0.01 15.7 6.5 0.01 15.7 4.5 3.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 GAO85900.1 - 0.013 13.3 34.8 0.4 8.3 24.6 2.2 1 1 0 1 1 1 0 Myosin tail WXG100 PF06013.7 GAO85900.1 - 0.015 15.2 7.5 8.5 6.4 0.0 4.0 3 1 1 4 4 3 0 Proteins of 100 residues with WXG WEMBL PF05701.6 GAO85900.1 - 0.017 13.5 37.0 0.15 10.5 7.2 3.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light APG6 PF04111.7 GAO85900.1 - 0.019 13.9 35.0 0.04 12.9 12.6 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 FlaC_arch PF05377.6 GAO85900.1 - 0.022 14.6 5.7 17 5.3 0.0 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 GAO85900.1 - 0.03 14.0 1.0 0.03 14.0 0.7 5.7 5 1 1 6 6 5 0 Homeobox associated leucine zipper GAS PF13851.1 GAO85900.1 - 0.033 13.3 32.4 0.12 11.5 1.5 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 GAO85900.1 - 0.061 13.6 24.4 0.4 11.0 1.7 5.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) LPP PF04728.8 GAO85900.1 - 0.064 13.0 2.6 4.3 7.2 0.1 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.17 GAO85900.1 - 0.12 12.4 27.1 0.081 12.9 5.2 3.6 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 GAO85900.1 - 0.13 11.7 24.8 0.74 9.3 2.0 5.1 3 1 1 5 5 5 0 Septum formation initiator DUF948 PF06103.6 GAO85900.1 - 0.13 12.1 9.0 5.3 6.9 0.6 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2353 PF09789.4 GAO85900.1 - 0.17 11.0 28.4 0.33 10.1 10.6 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.6 GAO85900.1 - 0.36 10.6 34.8 16 5.2 18.7 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 GAO85900.1 - 0.42 10.5 33.8 0.33 10.8 4.3 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 GAO85900.1 - 0.5 10.4 28.5 3.2 7.8 1.9 4.7 1 1 3 4 4 4 0 DivIVA protein TPR_MLP1_2 PF07926.7 GAO85900.1 - 0.7 9.6 35.9 1.3 8.7 11.9 3.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Sipho_Gp157 PF05565.6 GAO85900.1 - 0.98 8.9 13.5 0.7 9.4 1.8 3.1 2 1 0 3 3 3 0 Siphovirus Gp157 NYD-SP28_assoc PF14775.1 GAO85900.1 - 1.2 8.8 15.3 1.6 8.4 0.2 4.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain Snapin_Pallidin PF14712.1 GAO85900.1 - 1.5 9.1 24.9 0.12 12.6 1.7 3.5 2 2 1 3 3 3 0 Snapin/Pallidin Reo_sigmaC PF04582.7 GAO85900.1 - 1.8 7.6 12.4 1.4 8.0 5.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 GAO85900.1 - 2.1 8.3 28.9 0.25 11.3 1.0 5.8 3 2 2 6 6 6 0 bZIP transcription factor Filament PF00038.16 GAO85900.1 - 3 7.2 30.3 3.2 7.1 6.4 3.2 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.7 GAO85900.1 - 3.3 7.5 16.8 1.1 9.0 1.7 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 GAO85900.1 - 3.3 7.2 35.9 0.4 10.2 14.2 2.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 FUSC PF04632.7 GAO85900.1 - 3.5 5.9 13.0 3.3 6.0 7.9 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Mto2_bdg PF12808.2 GAO85900.1 - 3.5 7.8 13.4 0.41 10.7 1.8 4.1 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RTBV_P46 PF06216.6 GAO85900.1 - 3.8 6.2 8.8 1.2 7.8 0.6 2.7 1 1 0 3 3 3 0 Rice tungro bacilliform virus P46 protein NPV_P10 PF05531.7 GAO85900.1 - 4.2 7.6 11.2 5.1 7.4 1.0 3.9 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein DNA_repr_REX1B PF14966.1 GAO85900.1 - 4.3 7.7 12.0 0.67 10.3 0.2 3.4 2 2 0 3 3 3 0 DNA repair REX1-B Mnd1 PF03962.10 GAO85900.1 - 6.5 6.3 31.5 2.6 7.6 6.3 3.7 1 1 3 4 4 4 0 Mnd1 family DUF972 PF06156.8 GAO85900.1 - 6.9 7.0 26.4 7.1 7.0 1.6 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF972) THOC7 PF05615.8 GAO85900.1 - 8.2 6.7 26.8 1.5 9.0 6.8 3.8 1 1 2 3 3 3 0 Tho complex subunit 7 DUF4407 PF14362.1 GAO85900.1 - 9.9 5.0 19.0 86 1.9 13.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HET PF06985.6 GAO85901.1 - 2.1e-11 44.1 0.1 3.7e-10 40.1 0.0 2.6 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.13 GAO85902.1 - 0.033 13.3 0.0 0.085 12.0 0.0 1.6 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) FAA_hydrolase PF01557.13 GAO85903.1 - 3.1e-51 173.9 0.0 4.9e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAO85903.1 - 1.4e-19 70.0 0.0 7.3e-19 67.7 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GFA PF04828.9 GAO85905.1 - 5.2e-13 48.7 3.4 6.4e-06 26.0 1.0 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Metallophos PF00149.23 GAO85906.1 - 5.3e-17 61.8 0.0 1.3e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAO85906.1 - 3.6e-16 59.0 0.1 7.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAO85906.1 - 2.6e-07 29.5 0.3 4.4e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAO85906.1 - 0.047 13.5 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 GAO85907.1 - 4.1e-21 75.0 51.6 4.1e-21 75.0 35.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.1 GAO85907.1 - 8.6 5.4 6.3 2 7.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Fungal_trans_2 PF11951.3 GAO85908.1 - 1.2e-06 27.4 0.9 8.6e-06 24.5 0.3 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain HAD_2 PF13419.1 GAO85909.1 - 1.8e-20 73.8 0.0 2.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO85909.1 - 2.5e-14 54.2 0.0 4.4e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO85909.1 - 9.8e-12 44.4 0.0 2.8e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 GAO85909.1 - 3.1e-08 33.9 0.0 4.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAO85909.1 - 5.8e-05 22.9 0.0 0.043 13.7 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 GAO85909.1 - 0.11 11.8 0.0 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Fungal_trans_2 PF11951.3 GAO85910.1 - 8.2e-07 27.9 0.1 8.7e-06 24.5 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85910.1 - 4.6e-05 23.2 4.4 0.0001 22.1 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.5 GAO85911.1 - 5.5e-10 39.4 0.1 1.1e-08 35.1 0.0 2.9 2 1 0 2 2 2 1 CVNH domain DUF3773 PF12608.3 GAO85911.1 - 0.062 13.3 0.8 31 4.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3773) FUSC PF04632.7 GAO85911.1 - 1.8 6.9 5.0 2.5 6.4 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mnd1 PF03962.10 GAO85911.1 - 3.5 7.2 10.4 0.27 10.8 3.1 2.1 1 1 0 1 1 1 0 Mnd1 family DUF4267 PF14087.1 GAO85912.1 - 6.3e-31 106.2 3.8 7.3e-31 106.0 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.20 GAO85913.1 - 2.2e-16 59.7 0.0 3.7e-15 55.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85913.1 - 8.7e-07 28.2 0.0 0.063 12.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO85913.1 - 4.8e-05 22.4 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAO85913.1 - 9.4e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO85913.1 - 0.00021 20.4 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LANC_like PF05147.8 GAO85913.1 - 0.031 12.8 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein AA_permease_2 PF13520.1 GAO85914.1 - 9.1e-75 251.7 34.4 1.1e-74 251.4 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO85914.1 - 5e-24 84.4 30.8 6.8e-24 84.0 21.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3431 PF11913.3 GAO85915.1 - 7.1e-78 261.1 0.0 3.7e-77 258.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) MFS_1 PF07690.11 GAO85916.1 - 2.5e-30 105.3 49.1 2.4e-29 102.1 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 GAO85917.1 - 5.5e-77 258.3 0.0 6.9e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aminotran_1_2 PF00155.16 GAO85918.1 - 4.4e-41 141.0 0.0 5.6e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO85918.1 - 9.5e-10 38.0 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAO85918.1 - 6.3e-07 28.0 0.0 8.7e-07 27.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO85918.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO85918.1 - 0.064 12.3 0.0 0.18 10.9 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.17 GAO85919.1 - 7.1e-54 183.0 0.0 9.8e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 GAO85920.1 - 3.8e-39 134.0 0.1 7.3e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAO85920.1 - 1.8e-08 33.9 4.8 1.4e-05 24.5 0.0 3.0 2 2 1 3 3 3 2 Terpene synthase family, metal binding domain DUF3425 PF11905.3 GAO85921.1 - 1.9e-34 118.4 0.1 3.8e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO85921.1 - 0.015 15.2 8.6 0.035 14.0 5.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor G3P_antiterm PF04309.7 GAO85921.1 - 0.07 12.1 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator ABC2_membrane PF01061.19 GAO85923.1 - 8.6e-89 296.2 50.8 1.6e-48 164.6 15.3 2.8 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAO85923.1 - 1.4e-38 132.2 0.0 4.7e-18 65.8 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 GAO85923.1 - 1.7e-36 123.9 6.3 5.6e-33 112.6 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 GAO85923.1 - 7.8e-21 73.9 0.0 1.9e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO85923.1 - 3.9e-07 29.6 0.0 0.0015 18.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAO85923.1 - 4.9e-07 29.1 41.7 0.00072 18.6 12.3 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 GAO85923.1 - 2.5e-06 27.4 0.1 0.023 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO85923.1 - 3.6e-05 23.0 0.0 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAO85923.1 - 5.3e-05 23.2 0.2 0.0042 17.0 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAO85923.1 - 0.00016 21.1 0.8 0.024 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 GAO85923.1 - 0.00035 19.8 0.0 0.16 11.1 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO85923.1 - 0.00037 20.5 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAO85923.1 - 0.0005 20.8 0.0 0.18 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO85923.1 - 0.0013 19.0 0.0 0.088 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAO85923.1 - 0.0015 18.0 0.2 0.044 13.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 GAO85923.1 - 0.0019 18.3 0.2 0.98 9.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO85923.1 - 0.0036 17.0 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 GAO85923.1 - 0.0078 16.7 0.0 4.1 7.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 GAO85923.1 - 0.042 14.0 0.1 17 5.6 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAO85923.1 - 0.057 13.0 3.3 5.1 6.7 0.3 3.2 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 GAO85923.1 - 0.067 12.6 0.4 3.9 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 GAO85923.1 - 0.087 12.4 0.4 5 6.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 GAO85923.1 - 0.11 12.7 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAO85923.1 - 0.14 12.0 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 GAO85923.1 - 0.16 10.6 0.0 0.81 8.2 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 GAO85923.1 - 0.31 10.7 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 GAO85923.1 - 0.62 9.5 1.5 12 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain CBM_14 PF01607.19 GAO85924.1 - 9.3e-09 35.0 5.8 1.3e-08 34.6 4.0 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Meleagrin PF08189.6 GAO85924.1 - 0.16 11.4 2.8 5.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Meleagrin/Cygnin family Ldl_recept_a PF00057.13 GAO85924.1 - 0.31 10.9 2.0 4.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TILa PF12714.2 GAO85924.1 - 2.8 7.7 6.4 6.9 6.5 4.5 1.7 1 1 0 1 1 1 0 TILa domain CytochromB561_N PF09786.4 GAO85925.1 - 0.39 9.1 12.5 0.51 8.7 8.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 GAO85925.1 - 4.9 5.2 10.5 5 5.2 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 GAO85925.1 - 8.1 5.3 7.7 8.4 5.3 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain p450 PF00067.17 GAO85927.1 - 4.2e-61 206.8 0.0 5.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FB_lectin PF07367.6 GAO85928.1 - 5.4e-52 175.1 0.0 6e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin DUF1806 PF08830.5 GAO85928.1 - 0.038 13.7 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) WD40 PF00400.27 GAO85929.1 - 1.1e-82 269.2 30.3 1.5e-12 46.9 0.2 13.2 13 0 0 13 13 13 12 WD domain, G-beta repeat NACHT PF05729.7 GAO85929.1 - 4.2e-14 52.5 0.1 8.2e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 GAO85929.1 - 4.7e-11 41.5 7.2 0.33 9.0 0.6 7.9 2 1 5 7 7 7 5 Nucleoporin Nup120/160 eIF2A PF08662.6 GAO85929.1 - 8.5e-09 35.4 4.0 0.0022 17.7 0.1 5.0 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 GAO85929.1 - 1.5e-07 31.5 0.1 5.6e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain CDtoxinA PF03498.9 GAO85929.1 - 6.2e-07 28.8 0.9 0.93 8.8 0.0 6.0 4 3 1 5 5 5 1 Cytolethal distending toxin A/C family Nucleoporin_N PF08801.6 GAO85929.1 - 9.2e-07 27.9 8.2 0.012 14.3 0.3 3.9 1 1 2 3 3 3 2 Nup133 N terminal like AAA_22 PF13401.1 GAO85929.1 - 0.0005 20.2 0.0 0.0024 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytochrom_D1 PF02239.11 GAO85929.1 - 0.00051 18.4 2.3 1.7 6.8 0.0 3.3 2 1 0 3 3 3 2 Cytochrome D1 heme domain UPF0079 PF02367.12 GAO85929.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PIF1 PF05970.9 GAO85929.1 - 0.062 12.2 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase PPV_E1_C PF00519.12 GAO85929.1 - 0.25 9.9 0.0 0.48 8.9 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase PrsW-protease PF13367.1 GAO85930.1 - 9.6e-20 70.5 1.0 2.1e-19 69.4 0.7 1.7 1 1 0 1 1 1 1 Protease prsW family DUF2324 PF10086.4 GAO85930.1 - 0.0012 18.0 0.2 0.0039 16.4 0.0 1.9 2 0 0 2 2 2 1 Putative membrane peptidase family (DUF2324) Peptidase_A8 PF01252.13 GAO85930.1 - 0.011 15.3 0.0 0.05 13.2 0.0 2.1 1 1 1 2 2 2 0 Signal peptidase (SPase) II Zn_peptidase_2 PF04298.7 GAO85930.1 - 0.028 13.7 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Cerato-platanin PF07249.7 GAO85931.1 - 6.4e-17 61.6 0.2 9e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 GAO85931.1 - 3.6e-05 23.4 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Barwin family Pkinase PF00069.20 GAO85931.1 - 0.00057 19.1 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 GAO85932.1 - 6.8e-48 163.0 0.1 1.2e-46 158.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO85932.1 - 1.8e-22 79.6 0.0 2.4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO85932.1 - 0.0034 16.3 0.0 0.71 8.7 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 GAO85932.1 - 0.0037 16.3 0.1 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAO85932.1 - 0.0058 16.0 0.1 0.0089 15.3 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 GAO85932.1 - 0.0067 15.2 0.3 0.0096 14.7 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Ank PF00023.25 GAO85932.1 - 0.037 13.8 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 GAO85932.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) VirDNA-topo-I_N PF09266.5 GAO85932.1 - 0.14 12.0 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal AIG2 PF06094.7 GAO85933.1 - 2.2e-11 44.1 0.0 3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family APH PF01636.18 GAO85934.1 - 4.7e-11 42.8 0.8 7.3e-10 38.9 0.5 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO85934.1 - 0.0036 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Glyoxalase PF00903.20 GAO85935.1 - 6.8e-17 61.6 0.0 7.6e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO85935.1 - 1.2e-14 54.8 0.1 1.4e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAO85935.1 - 4.7e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAO85935.1 - 0.00011 22.1 0.0 0.011 15.6 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase-like domain ABC_membrane PF00664.18 GAO85936.1 - 1.5e-79 267.2 41.8 3.7e-41 141.3 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO85936.1 - 6.3e-67 224.0 0.0 6.1e-34 117.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAO85936.1 - 2e-13 50.0 1.9 0.01 15.0 0.0 5.4 4 1 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO85936.1 - 1.7e-12 47.8 0.2 0.023 14.6 0.0 4.4 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 GAO85936.1 - 4.8e-11 42.9 1.6 1.4e-06 28.4 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 GAO85936.1 - 3.9e-09 36.7 0.7 0.016 15.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO85936.1 - 4.1e-09 35.8 1.0 6.3e-05 22.4 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO85936.1 - 4.7e-08 33.8 0.0 0.0065 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAO85936.1 - 9.3e-08 31.0 0.3 0.0015 17.1 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAO85936.1 - 2.2e-07 30.2 0.0 0.012 14.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAO85936.1 - 4.3e-06 27.2 0.1 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO85936.1 - 6.1e-06 25.7 0.1 0.25 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 GAO85936.1 - 8.7e-06 25.9 3.1 0.17 12.0 0.2 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAO85936.1 - 2.9e-05 23.9 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAO85936.1 - 3.6e-05 23.4 0.0 0.051 13.3 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 GAO85936.1 - 4e-05 23.3 0.1 0.94 9.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 GAO85936.1 - 4.1e-05 23.2 0.2 0.31 10.5 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAO85936.1 - 9.4e-05 22.3 0.0 0.13 12.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 GAO85936.1 - 0.00013 21.6 0.1 0.39 10.4 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAO85936.1 - 0.00034 20.9 0.0 0.59 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAO85936.1 - 0.00086 19.1 0.8 0.58 10.1 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 GAO85936.1 - 0.0011 18.1 0.0 0.12 11.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 GAO85936.1 - 0.0013 18.2 4.2 0.52 9.6 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_28 PF13521.1 GAO85936.1 - 0.0014 18.6 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAO85936.1 - 0.0031 17.6 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 GAO85936.1 - 0.0046 16.4 0.0 0.86 9.0 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 GAO85936.1 - 0.0069 15.2 0.1 2.4 6.9 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain ATP-synt_ab PF00006.20 GAO85936.1 - 0.0095 15.4 0.0 2.7 7.4 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 GAO85936.1 - 0.011 14.5 0.0 0.19 10.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 GAO85936.1 - 0.027 14.1 0.1 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.13 GAO85936.1 - 0.042 13.4 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 GAO85936.1 - 0.055 13.1 0.1 9.8 5.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain DUF87 PF01935.12 GAO85936.1 - 0.066 13.0 0.1 4.9 6.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 GAO85936.1 - 0.066 12.6 1.1 18 4.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAO85936.1 - 0.08 12.0 0.0 4.5 6.3 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 GAO85936.1 - 0.084 11.5 0.0 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 GAO85936.1 - 0.1 12.1 0.1 8.9 5.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 GAO85936.1 - 0.11 12.4 0.0 25 4.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MoaE PF02391.12 GAO85936.1 - 0.11 12.2 1.3 3.3 7.5 0.1 2.5 2 0 0 2 2 2 0 MoaE protein AAA_15 PF13175.1 GAO85936.1 - 0.23 10.4 0.0 2 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.13 GAO85937.1 - 0.00013 20.9 0.1 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAPEG PF01124.13 GAO85938.1 - 1.3e-13 50.6 3.5 1.6e-13 50.3 2.4 1.2 1 0 0 1 1 1 1 MAPEG family Glyco_hydro_25 PF01183.15 GAO85938.1 - 0.13 12.1 0.2 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 DUF3425 PF11905.3 GAO85939.1 - 2.7e-28 98.5 0.2 5.2e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO85939.1 - 0.01 15.7 2.4 0.018 15.0 1.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor SecG PF03840.9 GAO85940.1 - 0.99 9.1 8.9 0.38 10.5 4.0 2.0 1 1 1 2 2 2 0 Preprotein translocase SecG subunit BMF PF15185.1 GAO85940.1 - 8.1 5.6 5.7 12 5.0 4.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis AA_permease_2 PF13520.1 GAO85941.1 - 3.7e-71 239.8 45.8 4.6e-71 239.5 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO85941.1 - 4.2e-24 84.7 35.1 5.6e-24 84.3 24.3 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 GAO85943.1 - 0.048 13.1 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 GAO85945.1 - 1.8e-39 135.4 37.1 2.2e-39 135.1 25.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_3 PF13302.1 GAO85945.1 - 5.5e-31 107.6 0.0 9.1e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 GAO85945.1 - 2.8e-14 52.5 8.4 2.8e-14 52.5 5.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1228 PF06779.9 GAO85945.1 - 0.0037 17.2 0.1 0.013 15.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) DUF4117 PF13491.1 GAO85945.1 - 0.0086 15.5 5.2 0.0086 15.5 3.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4117) OATP PF03137.15 GAO85945.1 - 0.009 14.1 1.2 0.098 10.6 0.4 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_1 PF00583.19 GAO85945.1 - 0.025 14.5 0.2 0.07 13.1 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO85945.1 - 0.056 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.16 GAO85947.1 - 1.3e-21 77.1 0.0 2.7e-21 76.0 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO85947.1 - 1.9e-12 46.4 0.0 2.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO85947.1 - 6.5e-12 45.8 0.0 8.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO85947.1 - 1.2e-06 27.9 0.0 2.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 GAO85947.1 - 2e-05 23.6 0.0 5.6e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO85947.1 - 4.1e-05 22.6 0.7 0.00021 20.2 0.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO85947.1 - 4.1e-05 22.5 0.2 8.7e-05 21.5 0.2 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAO85947.1 - 0.00066 19.6 0.9 0.014 15.3 0.6 2.3 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 GAO85947.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAO85947.1 - 0.003 17.8 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAO85948.1 - 3.9e-06 26.8 0.0 6.3e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO85948.1 - 0.00014 21.6 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO85948.1 - 0.0038 17.3 0.0 0.079 13.0 0.0 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO85948.1 - 0.012 14.5 0.1 0.028 13.3 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAO85948.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Lactamase_B PF00753.22 GAO85949.1 - 1.7e-22 79.9 1.4 2.4e-22 79.5 1.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO85949.1 - 0.0012 18.4 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1749 PF08538.5 GAO85950.1 - 1.5e-100 336.0 0.0 1.6e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 GAO85950.1 - 2.5e-06 27.2 0.0 6.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO85950.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 GAO85950.1 - 0.16 11.3 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) SVS_QK PF10578.4 GAO85950.1 - 0.24 11.8 1.0 0.46 10.9 0.7 1.5 1 0 0 1 1 1 0 Seminal vesicle protein repeat Prenyltrans_2 PF13249.1 GAO85952.1 - 1.4e-27 96.3 0.3 3e-10 40.4 0.0 4.5 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAO85952.1 - 7.4e-27 93.5 0.7 6e-12 45.5 0.0 5.4 3 2 3 6 6 6 3 Prenyltransferase-like Prenyltrans PF00432.16 GAO85952.1 - 2e-18 65.6 13.8 6.5e-05 22.4 0.0 6.0 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 GAO85952.1 - 0.00091 18.5 0.0 0.55 9.4 0.0 2.9 2 1 2 4 4 4 3 A-macroglobulin complement component Pec_lyase PF09492.5 GAO85952.1 - 0.0095 15.1 0.1 2.4 7.2 0.0 3.7 2 1 2 4 4 4 1 Pectic acid lyase ketoacyl-synt PF00109.21 GAO85953.1 - 3.8e-75 252.6 0.0 8.3e-75 251.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO85953.1 - 2.5e-48 165.0 0.1 4.4e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAO85953.1 - 2.9e-46 157.9 0.0 1.9e-45 155.2 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 GAO85953.1 - 8.7e-44 149.3 0.9 2.8e-43 147.6 0.0 2.4 3 0 0 3 3 2 1 KR domain adh_short PF00106.20 GAO85953.1 - 7.8e-40 136.5 0.0 2.4e-39 134.9 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO85953.1 - 4.8e-31 107.0 0.0 1.7e-30 105.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO85953.1 - 1.4e-19 70.3 0.0 3.9e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO85953.1 - 4.6e-14 52.4 0.0 1.3e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85953.1 - 1.2e-13 51.2 0.0 3.7e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85953.1 - 3.5e-10 40.4 0.0 2.4e-09 37.7 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85953.1 - 2.1e-09 37.1 0.0 6.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO85953.1 - 1.2e-06 27.7 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 GAO85953.1 - 7.9e-06 26.0 0.0 2.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO85953.1 - 0.0035 16.3 0.0 0.007 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 GAO85953.1 - 0.0064 15.7 0.0 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family DUF938 PF06080.7 GAO85953.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.15 GAO85953.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 GAO85953.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 GAO85953.1 - 0.023 14.2 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.11 GAO85954.1 - 9e-21 73.9 26.7 1.2e-20 73.5 18.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAO85954.1 - 0.0023 16.3 5.0 0.0023 16.3 3.5 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein DUF791 PF05631.9 GAO85954.1 - 0.013 14.2 0.7 0.018 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF791) DUF1228 PF06779.9 GAO85954.1 - 0.014 15.4 1.8 0.021 14.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DUF3605 PF12239.3 GAO85955.1 - 4e-60 202.2 0.3 5e-60 201.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) p450 PF00067.17 GAO85956.1 - 2.7e-29 102.0 0.0 3.7e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 GAO85957.1 - 9.1e-25 87.4 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAO85957.1 - 2.2e-06 26.8 0.1 0.00098 18.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 GAO85957.1 - 7.2e-06 25.3 0.0 0.01 14.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAO85957.1 - 1.6e-05 23.9 0.1 0.03 13.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO85957.1 - 0.0013 18.6 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO85957.1 - 0.011 14.6 0.1 0.019 13.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAO85957.1 - 0.02 15.3 0.2 0.29 11.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO85957.1 - 0.027 14.3 0.1 0.13 12.0 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO85957.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Prenyltrans_2 PF13249.1 GAO85958.1 - 4.4e-34 117.2 7.0 1.2e-15 57.8 0.0 6.1 3 1 3 6 6 6 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAO85958.1 - 1.5e-30 105.4 6.3 1.1e-15 57.5 0.1 6.4 3 3 4 7 7 7 6 Prenyltransferase-like Prenyltrans PF00432.16 GAO85958.1 - 1.4e-18 66.1 18.6 8.8e-07 28.3 0.0 7.0 8 0 0 8 8 8 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 GAO85958.1 - 2.5e-07 30.1 0.1 1.4 8.0 0.0 4.5 4 1 1 5 5 5 4 Pectic acid lyase A2M_comp PF07678.9 GAO85958.1 - 6e-05 22.4 0.0 0.11 11.7 0.0 3.6 4 0 0 4 4 4 2 A-macroglobulin complement component Hydantoinase_A PF01968.13 GAO85959.1 - 5.1e-89 298.2 4.7 1.7e-88 296.5 0.8 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 GAO85959.1 - 1.6e-67 227.9 0.0 2.6e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 GAO85959.1 - 9e-49 165.3 0.3 3.4e-46 156.9 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 GAO85959.1 - 3.3e-06 25.7 2.3 0.0029 16.0 0.1 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 GAO85959.1 - 0.022 14.0 0.2 1.9 7.6 0.0 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF2497 PF10691.4 GAO85959.1 - 4.6 7.2 6.3 67 3.5 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2497) Aa_trans PF01490.13 GAO85960.1 - 2.6e-26 92.0 30.9 3.5e-26 91.6 21.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 GAO85960.1 - 0.02 13.4 42.1 1.1 7.6 29.2 2.3 1 1 0 1 1 1 0 Amino acid permease CRAL_TRIO_2 PF13716.1 GAO85960.1 - 0.13 12.2 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Tubulin PF00091.20 GAO85962.1 - 1.4e-67 227.6 0.0 2.2e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAO85962.1 - 9e-46 155.0 0.1 1.4e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAO85962.1 - 6.7e-06 26.1 0.4 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAO85962.1 - 0.005 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GH97_C PF14509.1 GAO85962.1 - 0.13 12.4 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Mito_carr PF00153.22 GAO85963.1 - 1.4e-43 146.5 8.4 9.5e-17 60.5 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1857 PF08982.6 GAO85964.1 - 2.2e-45 153.8 0.0 2.5e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) APH PF01636.18 GAO85965.1 - 3.9e-12 46.4 0.0 2.1e-11 43.9 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAO85965.1 - 0.00064 18.9 0.0 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 GAO85965.1 - 0.0099 14.5 0.0 0.082 11.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) CcmD PF04995.9 GAO85966.1 - 0.25 11.1 1.6 0.59 9.9 1.1 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Peptidase_M20 PF01546.23 GAO85970.1 - 7.2e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-grasp_4 PF13535.1 GAO85971.1 - 2.7e-07 30.4 0.0 3.2e-06 27.0 0.0 2.4 2 1 1 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAO85971.1 - 0.00065 18.5 0.0 0.03 13.0 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DUF1030 PF06270.6 GAO85971.1 - 0.12 11.9 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Fungal_trans PF04082.13 GAO85972.1 - 2e-09 36.7 0.0 4.6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.16 GAO85973.1 - 3.3e-37 128.1 9.2 4.8e-37 127.6 6.4 1.3 1 0 0 1 1 1 1 POT family Beta-lactamase PF00144.19 GAO85974.1 - 2.6e-23 82.5 0.0 2.8e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Beta-lactamase DUF3471 PF11954.3 GAO85974.1 - 0.0019 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Piwi PF02171.12 GAO85975.1 - 2.4e-69 233.6 0.0 3.8e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAO85975.1 - 7.3e-09 35.0 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAO85975.1 - 2.5e-05 23.5 0.0 6.3e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) FtsJ PF01728.14 GAO85978.1 - 3.4e-11 43.4 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 GAO85978.1 - 0.011 16.2 0.1 0.12 12.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 GAO85978.1 - 0.075 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NOL1/NOP2/sun family HET PF06985.6 GAO85979.1 - 4.1e-06 26.9 0.5 0.00071 19.7 0.3 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL_2 PF13472.1 GAO85980.1 - 5.9e-06 26.5 0.0 3.7e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO85980.1 - 0.0021 17.9 0.0 0.0056 16.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAO85980.1 - 0.0047 16.6 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CsiD PF08943.5 GAO85980.1 - 0.12 11.2 0.1 6 5.6 0.0 2.2 2 0 0 2 2 2 0 CsiD fn3 PF00041.16 GAO85980.1 - 0.2 11.7 4.1 3.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Fibronectin type III domain Fungal_trans PF04082.13 GAO85981.1 - 1.7e-12 46.7 1.7 2.8e-12 46.0 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO85981.1 - 2.2e-07 30.6 9.5 4.1e-07 29.8 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAO85981.1 - 1 9.5 7.8 2.2 8.5 5.4 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 GAO85982.1 - 4.6e-09 35.4 50.7 8.8e-08 31.2 21.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO85983.1 - 0.0059 15.5 0.1 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 GAO85984.1 - 1.6e-18 67.4 0.3 2.1e-18 67.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO85984.1 - 7.4e-08 32.2 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO85984.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO85984.1 - 0.0025 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1656 PF07869.7 GAO85985.1 - 0.026 14.2 0.5 0.087 12.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Peroxidase_2 PF01328.12 GAO85986.1 - 6e-26 90.8 0.0 2.3e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 Aldedh PF00171.17 GAO85987.1 - 1.1e-23 83.2 0.1 3e-23 81.8 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ketoacyl-synt PF00109.21 GAO85988.1 - 2.4e-71 240.1 1.1 2.4e-71 240.1 0.8 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO85988.1 - 5.6e-58 196.7 0.1 1.1e-57 195.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAO85988.1 - 1.2e-55 187.9 0.2 3.3e-55 186.5 0.2 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAO85988.1 - 4.9e-44 150.6 0.0 9.3e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAO85988.1 - 1.2e-38 132.7 0.3 4.2e-38 130.8 0.2 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO85988.1 - 2e-38 130.8 0.7 2e-38 130.8 0.5 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAO85988.1 - 3.2e-22 78.4 0.1 1.6e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAO85988.1 - 6.1e-18 65.1 0.0 1.9e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAO85988.1 - 2.1e-14 54.5 0.1 3.5e-13 50.5 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAO85988.1 - 5.8e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO85988.1 - 8e-11 42.5 0.0 3.7e-10 40.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO85988.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO85988.1 - 2.5e-08 34.2 0.0 6.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO85988.1 - 6.3e-08 32.0 0.0 1.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAO85988.1 - 1.2e-05 25.5 0.0 4.2e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO85988.1 - 2.8e-05 24.1 0.0 0.00014 21.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAO85988.1 - 0.00038 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_24 PF13578.1 GAO85988.1 - 0.0091 16.8 0.0 0.057 14.2 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO85988.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAO85988.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase ADH_N PF08240.7 GAO85988.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAO85988.1 - 0.061 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PCMT PF01135.14 GAO85988.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_gyraseB_C PF00986.16 GAO85988.1 - 0.17 11.6 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Methyltransf_28 PF02636.12 GAO85988.1 - 0.21 10.9 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Transferase PF02458.10 GAO85989.1 - 4.9e-18 64.7 0.0 7.3e-13 47.7 0.0 2.8 2 1 0 2 2 2 2 Transferase family AMP-binding PF00501.23 GAO85990.1 - 8.2e-68 228.6 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO85990.1 - 4.2e-14 53.2 0.1 1.3e-13 51.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 GAO85991.1 - 2.3e-162 540.1 0.8 1.3e-82 277.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO85991.1 - 2.5e-150 499.3 0.0 1.4e-41 142.2 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAO85991.1 - 1.3e-34 118.2 0.1 1.4e-10 41.2 0.0 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO85991.1 - 4.4e-07 30.7 0.1 0.051 14.5 0.0 3.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Thioredoxin_9 PF14595.1 GAO85991.1 - 0.46 10.0 0.0 0.97 9.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin OmpH PF03938.9 GAO85992.1 - 0.062 13.2 0.2 0.089 12.7 0.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HTH_psq PF05225.11 GAO85994.1 - 1.6e-06 27.5 0.1 2.2e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 GAO85994.1 - 0.00052 19.5 0.1 0.00072 19.1 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 GAO85994.1 - 0.00058 19.7 0.1 0.0006 19.7 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 GAO85994.1 - 0.0048 16.8 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 GAO85994.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 MarR family DUF1441 PF07278.6 GAO85994.1 - 0.036 13.7 0.1 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) HTH_30 PF13556.1 GAO85994.1 - 0.056 13.0 0.3 0.076 12.6 0.2 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain CENP-B_N PF04218.8 GAO85994.1 - 0.074 12.4 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.7 GAO85994.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.1 GAO85994.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ketoacyl-synt PF00109.21 GAO85995.1 - 8.2e-38 130.3 0.7 1.9e-26 93.1 0.0 3.0 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAO85995.1 - 8.9e-32 109.4 0.5 2.3e-31 108.0 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO85995.1 - 1.4e-29 104.0 0.0 1.9e-28 100.2 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAO85995.1 - 1.7e-19 69.8 0.5 4e-09 36.6 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 GAO85995.1 - 1.5e-11 44.1 2.6 7.9e-10 38.5 0.2 2.9 2 1 0 2 2 2 2 Acyl transferase domain SnoaL_4 PF13577.1 GAO85997.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain ABC2_membrane PF01061.19 GAO85998.1 - 1.1e-87 292.6 49.1 1.4e-47 161.5 12.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAO85998.1 - 2.6e-37 128.1 0.0 1.3e-18 67.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO85998.1 - 1e-29 102.2 0.1 1.3e-24 85.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAO85998.1 - 3e-14 52.8 26.5 5.2e-10 38.8 7.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAO85998.1 - 1e-08 35.1 0.0 2.8e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO85998.1 - 1.3e-06 27.9 0.0 0.0017 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO85998.1 - 0.0001 21.5 0.2 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO85998.1 - 0.00035 20.7 0.0 0.045 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO85998.1 - 0.00046 20.2 0.8 0.048 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 GAO85998.1 - 0.0017 17.8 1.8 0.42 10.0 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 GAO85998.1 - 0.0023 17.4 0.8 0.075 12.5 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 GAO85998.1 - 0.0032 17.4 0.6 0.33 10.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO85998.1 - 0.023 15.0 0.0 0.92 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAO85998.1 - 0.041 13.6 1.1 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 GAO85998.1 - 0.046 14.5 0.0 1.5 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAO85998.1 - 0.093 13.2 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 GAO85998.1 - 0.12 11.8 0.3 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 GAO85998.1 - 0.12 12.0 0.8 4.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 GAO85998.1 - 0.18 11.6 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAO85998.1 - 0.21 11.7 0.0 30 4.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) A_deaminase PF00962.17 GAO86001.1 - 4.6e-112 374.1 0.0 6.9e-112 373.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.1 GAO86002.1 - 3.7e-29 100.0 5.2 7.8e-16 57.3 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAO86002.1 - 1.8e-26 91.2 5.6 3.7e-14 51.8 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAO86002.1 - 8.4e-19 66.8 0.7 1.8e-08 33.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 GAO86002.1 - 3.4e-10 39.8 0.0 5.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 GAO86003.1 - 6.9e-101 336.9 0.0 1.4e-97 326.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 GAO86003.1 - 6.9e-55 185.4 0.0 1.9e-54 183.9 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAO86003.1 - 1.5e-31 108.1 1.4 1.5e-31 108.1 0.9 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAO86003.1 - 0.00044 20.1 0.2 0.0047 16.8 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO86003.1 - 0.015 15.8 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 GAO86003.1 - 0.034 13.4 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SOBP PF15279.1 GAO86003.1 - 0.054 13.8 4.2 0.11 12.8 2.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein zf-CCHC_4 PF14392.1 GAO86003.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Rad17 PF03215.10 GAO86004.1 - 4.8e-57 193.8 0.0 8.7e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein T2SE PF00437.15 GAO86004.1 - 0.00034 19.6 0.0 0.00067 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 GAO86004.1 - 0.00037 21.2 0.0 0.00094 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO86004.1 - 0.0006 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAO86004.1 - 0.00082 19.4 0.1 0.0069 16.3 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAO86004.1 - 0.0014 18.8 0.0 0.0052 16.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAO86004.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAO86004.1 - 0.038 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO86004.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAO86004.1 - 0.062 12.9 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 GAO86004.1 - 0.063 13.5 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 GAO86004.1 - 0.079 12.8 0.1 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ELMO_CED12 PF04727.8 GAO86005.1 - 1.1e-50 171.5 0.3 1.7e-50 170.8 0.2 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 GAO86005.1 - 2.6e-06 27.2 0.0 5.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Sec10 PF07393.6 GAO86007.1 - 1.5e-248 826.6 0.0 1.8e-248 826.4 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 BNR PF02012.15 GAO86008.1 - 3e-07 29.2 36.4 0.66 10.0 0.2 10.0 10 0 0 10 10 10 6 BNR/Asp-box repeat Mo-co_dimer PF03404.11 GAO86008.1 - 1 8.9 4.8 26 4.4 0.0 4.6 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain dCMP_cyt_deam_1 PF00383.17 GAO86009.1 - 1e-11 44.3 1.0 1.1e-11 44.2 0.7 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 GAO86009.1 - 3.1e-10 40.1 0.3 3.9e-10 39.8 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 GAO86009.1 - 0.009 15.4 0.2 0.009 15.4 0.1 1.2 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.22 GAO86010.1 - 1.8e-52 175.0 0.1 6e-23 80.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SUI1 PF01253.17 GAO86011.1 - 2.4e-22 78.5 2.2 3.4e-22 78.0 1.1 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 Spore_III_AF PF09581.5 GAO86011.1 - 1.1 9.0 6.9 1.6 8.5 4.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF1752 PF08550.5 GAO86012.1 - 1.2e-11 43.9 1.7 2.4e-11 43.0 1.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans PF04082.13 GAO86013.1 - 2.6e-13 49.4 0.1 4.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86013.1 - 0.0037 17.1 3.7 0.0068 16.2 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 GAO86014.1 - 9.6e-54 182.3 0.0 1.4e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAO86014.1 - 1.3e-19 70.6 0.1 3.4e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAO86014.1 - 5e-15 55.3 0.0 1.1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO86014.1 - 3.8e-13 49.7 0.1 9.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAO86014.1 - 0.034 14.5 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 GAO86014.1 - 0.079 12.7 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 ThiF family Glyco_transf_8 PF01501.15 GAO86015.1 - 0.0017 17.7 1.2 0.015 14.6 0.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAO86015.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Chromate_transp PF02417.10 GAO86016.1 - 3.6e-53 179.6 34.2 7.9e-29 100.4 9.7 2.6 3 0 0 3 3 3 2 Chromate transporter Defensin_2 PF01097.13 GAO86017.1 - 3.5 7.4 12.1 0.3 10.8 4.1 2.0 1 1 1 2 2 2 0 Arthropod defensin Sugar_tr PF00083.19 GAO86018.1 - 5.9e-77 259.1 27.4 7e-77 258.9 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86018.1 - 1.2e-23 83.4 41.4 2.3e-17 62.7 8.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 GAO86018.1 - 0.012 15.3 1.1 0.012 15.3 0.8 2.0 2 1 0 2 2 2 0 Ligand-gated ion channel Zn_clus PF00172.13 GAO86019.1 - 8.5e-07 28.7 10.8 1.8e-06 27.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO86019.1 - 4.1e-05 22.3 0.3 6.4e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF89 PF01937.14 GAO86020.1 - 2.1e-99 332.7 0.5 2.4e-99 332.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 RecT PF03837.9 GAO86020.1 - 0.041 13.1 0.2 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 RecT family UPF0075 PF03702.9 GAO86021.1 - 2.1e-75 253.8 0.0 2.5e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) FGGY_C PF02782.11 GAO86021.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain ABC2_membrane PF01061.19 GAO86022.1 - 1e-75 253.4 48.4 1.5e-39 135.3 17.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAO86022.1 - 5.3e-36 123.9 0.0 4.5e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO86022.1 - 8.5e-25 86.4 0.0 4.1e-23 81.0 0.0 3.1 2 0 0 2 2 2 1 CDR ABC transporter Fungal_trans PF04082.13 GAO86022.1 - 1.4e-19 70.0 1.7 2.6e-19 69.1 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane_3 PF12698.2 GAO86022.1 - 1.5e-09 37.3 42.3 7.3e-07 28.5 10.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 GAO86022.1 - 1.4e-07 31.1 0.0 8.3e-05 22.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAO86022.1 - 4.6e-05 22.6 0.0 0.00031 19.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAO86022.1 - 0.00013 21.3 0.4 0.012 15.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO86022.1 - 0.00072 19.5 0.9 0.012 15.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAO86022.1 - 0.0013 18.3 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 GAO86022.1 - 0.004 17.1 0.0 0.26 11.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAO86022.1 - 0.0041 16.5 0.1 3.1 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 GAO86022.1 - 0.0067 16.5 0.1 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 GAO86022.1 - 0.0098 15.8 0.0 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.2 GAO86022.1 - 0.024 13.4 25.9 0.0098 14.7 5.5 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_33 PF13671.1 GAO86022.1 - 0.094 12.5 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAO86022.1 - 0.12 11.1 0.3 0.95 8.1 0.1 2.0 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 GAO86022.1 - 0.14 12.6 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 GAO86022.1 - 0.16 12.3 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 GAO86022.1 - 0.16 11.1 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 GAO86022.1 - 0.21 11.2 1.8 1.1 8.8 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 GAO86022.1 - 0.67 10.2 0.7 1.8 8.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAO86022.1 - 0.99 8.9 1.9 12 5.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAO86022.1 - 1.5 7.7 0.0 8.9 5.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 GAO86023.1 - 5.1e-48 162.8 3.5 1.6e-45 154.7 2.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_28 PF00295.12 GAO86023.1 - 1.5e-47 162.1 1.1 2.9e-47 161.2 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CobW_C PF07683.9 GAO86023.1 - 3.4e-20 71.5 0.0 8.9e-16 57.3 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 GAO86023.1 - 0.015 13.3 4.0 0.026 12.5 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_33 PF13671.1 GAO86023.1 - 0.024 14.5 0.1 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 GAO86023.1 - 0.038 14.1 0.1 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAO86023.1 - 0.039 13.4 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 GAO86023.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAO86023.1 - 0.39 11.0 0.0 0.39 11.0 0.0 3.1 3 1 1 4 4 4 0 AAA domain p450 PF00067.17 GAO86024.1 - 9.1e-78 261.8 0.0 1.2e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 A_deaminase PF00962.17 GAO86024.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase adh_short PF00106.20 GAO86025.1 - 5.5e-25 88.2 0.1 1.7e-24 86.6 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO86025.1 - 1.4e-10 41.3 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO86025.1 - 1e-07 31.7 0.7 1.8e-06 27.7 0.1 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAO86025.1 - 2.3e-05 23.9 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO86025.1 - 8.9e-05 22.5 0.0 0.00021 21.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAO86025.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UPF0146 PF03686.8 GAO86025.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Hydrolase_4 PF12146.3 GAO86025.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 GAO86026.1 - 4e-24 85.3 0.0 5.8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO86026.1 - 2.4e-15 56.0 0.0 7.2e-15 54.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAO86026.1 - 3.5e-05 23.5 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO86026.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyr_redox_3 PF13738.1 GAO86027.1 - 1e-25 91.0 0.0 2.5e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO86027.1 - 5.7e-14 51.2 0.0 3.5e-13 48.6 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAO86027.1 - 4.8e-11 42.5 0.0 1.8e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO86027.1 - 8.9e-09 34.7 0.0 5.2e-06 25.7 0.0 2.4 3 0 0 3 3 3 2 Thi4 family K_oxygenase PF13434.1 GAO86027.1 - 1.6e-07 30.5 0.1 3.2e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAO86027.1 - 3.4e-06 26.2 0.0 0.00053 19.0 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO86027.1 - 0.00018 21.4 1.6 0.33 10.8 0.0 3.0 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO86027.1 - 0.0007 19.9 0.0 0.13 12.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO86027.1 - 0.00082 18.3 0.0 0.087 11.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 GAO86027.1 - 0.0018 18.5 0.0 0.0078 16.4 0.0 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 GAO86027.1 - 0.0033 16.3 0.1 0.046 12.6 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 GAO86027.1 - 0.0069 16.4 0.0 0.091 12.8 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 GAO86027.1 - 0.007 15.4 0.0 0.016 14.3 0.0 1.5 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAO86027.1 - 0.0084 15.8 1.3 2.7 7.7 0.0 4.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO86027.1 - 0.094 11.1 0.2 0.61 8.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 GAO86027.1 - 0.13 11.3 0.0 0.87 8.5 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 GAO86027.1 - 0.14 11.0 1.4 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Gp_dh_C PF02800.15 GAO86028.1 - 9.6e-57 190.8 0.0 1.4e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAO86028.1 - 2.7e-50 170.2 0.0 6e-50 169.1 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO86028.1 - 0.00021 21.2 0.2 0.0021 17.9 0.0 2.7 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 GAO86028.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 GAO86028.1 - 0.049 14.1 0.4 0.68 10.4 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold PTR2 PF00854.16 GAO86029.1 - 1.4e-39 135.9 11.2 1.3e-38 132.7 7.8 2.2 1 1 0 1 1 1 1 POT family COesterase PF00135.23 GAO86030.1 - 2.5e-97 326.8 0.0 3.2e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO86030.1 - 3.6e-05 23.4 0.5 0.00034 20.2 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sulfatase PF00884.18 GAO86031.1 - 4.7e-62 209.9 0.5 7.1e-62 209.3 0.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAO86031.1 - 0.0043 16.4 2.3 0.04 13.2 1.6 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_43 PF04616.9 GAO86032.1 - 2.7e-20 72.6 1.7 4e-20 72.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GST_N PF02798.15 GAO86033.1 - 4.3e-11 42.8 0.0 7.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO86033.1 - 5.2e-11 42.6 0.0 8.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO86033.1 - 1.4e-10 41.0 0.1 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO86033.1 - 5.3e-08 33.2 0.0 8.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO86033.1 - 6.9e-07 29.0 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO86033.1 - 3e-05 23.9 0.0 6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAN_1 PF00024.21 GAO86034.1 - 0.00033 20.3 2.6 0.00033 20.3 1.8 2.2 1 1 1 2 2 2 1 PAN domain RskA PF10099.4 GAO86034.1 - 0.033 13.9 0.3 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1469 PF07332.6 GAO86034.1 - 0.051 13.3 0.3 0.075 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PAN_4 PF14295.1 GAO86034.1 - 0.24 11.1 5.1 2.1 8.0 0.7 2.9 1 1 1 2 2 2 0 PAN domain DUF212 PF02681.9 GAO86034.1 - 0.33 10.6 2.7 0.5 10.1 1.7 1.4 1 1 0 1 1 1 0 Divergent PAP2 family TPPK_C PF12555.3 GAO86034.1 - 0.73 9.5 4.8 1.4 8.6 3.3 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Myco_19_kDa PF05481.7 GAO86034.1 - 3.8 7.3 16.1 27 4.5 11.2 2.1 1 1 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen p450 PF00067.17 GAO86035.1 - 7.3e-58 196.2 0.0 1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.18 GAO86036.1 - 0.004 16.9 6.5 0.0069 16.2 4.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF1129 PF06570.6 GAO86036.1 - 0.4 9.9 2.4 0.4 9.9 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) MFS_1 PF07690.11 GAO86037.1 - 3.3e-26 91.8 22.1 4.5e-26 91.3 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 GAO86037.1 - 4.8e-10 39.9 0.9 4e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 GAO86037.1 - 1.5e-06 28.2 3.4 0.00076 19.4 1.1 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MTBP_N PF14918.1 GAO86038.1 - 0.16 11.3 0.1 3.5 6.9 0.0 2.3 2 1 1 3 3 3 0 MDM2-binding DUF2796 PF10986.3 GAO86038.1 - 1 9.3 10.4 1.5 8.8 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) FA_hydroxylase PF04116.8 GAO86039.1 - 7.7e-17 61.7 9.3 7.7e-17 61.7 6.5 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily ADH_N PF08240.7 GAO86040.1 - 4.7e-21 74.5 5.1 7.7e-21 73.9 3.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO86040.1 - 1e-18 67.1 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO86040.1 - 2.5e-06 28.3 0.0 4.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO86040.1 - 0.0033 16.5 0.2 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAO86040.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UbiA PF01040.13 GAO86042.1 - 6e-27 94.4 16.0 8.4e-27 94.0 11.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MscS_TM PF12794.2 GAO86042.1 - 1.8 7.0 14.2 0.011 14.3 3.5 1.9 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 TcpE PF12648.2 GAO86042.1 - 7.1 6.8 8.1 11 6.2 0.1 3.2 1 1 2 3 3 3 0 TcpE family polyprenyl_synt PF00348.12 GAO86043.1 - 5e-55 186.1 0.0 6.2e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAO86043.1 - 0.031 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain FAD_binding_3 PF01494.14 GAO86045.1 - 5.5e-27 94.7 0.1 2.7e-26 92.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO86045.1 - 3.5e-07 29.4 1.0 0.00023 20.1 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86045.1 - 2.2e-05 24.4 0.1 5.3e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAO86045.1 - 0.00032 19.8 0.1 0.014 14.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAO86045.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO86045.1 - 0.0035 16.3 0.8 0.15 10.9 0.2 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO86045.1 - 0.0064 15.3 1.1 0.0077 15.1 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAO86045.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAO86045.1 - 0.021 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AFOR_N PF02730.10 GAO86045.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain HI0933_like PF03486.9 GAO86045.1 - 0.22 9.9 0.1 0.53 8.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein T5orf172 PF10544.4 GAO86046.1 - 2e-20 73.0 1.1 6.3e-20 71.4 0.1 2.3 2 1 1 3 3 3 1 T5orf172 domain MUG113 PF13455.1 GAO86046.1 - 1e-18 67.5 0.6 5.2e-18 65.2 0.4 2.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 MBOAT_2 PF13813.1 GAO86047.1 - 2.9e-27 94.5 2.7 2.9e-27 94.5 1.9 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ketoacyl-synt PF00109.21 GAO86048.1 - 8e-73 245.0 1.3 1e-72 244.6 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAO86048.1 - 7.6e-36 122.5 0.0 1.6e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAO86048.1 - 2.7e-19 69.6 0.0 6.5e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 GAO86048.1 - 3e-16 59.4 0.0 1e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAO86048.1 - 5e-14 52.2 2.3 9.7e-07 28.9 0.6 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO86048.1 - 1.1e-06 27.7 0.7 2.4e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain HET PF06985.6 GAO86049.1 - 1e-15 58.1 0.9 2.7e-15 56.7 0.0 2.2 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) BNR_2 PF13088.1 GAO86051.1 - 3e-10 39.8 9.6 0.013 14.8 0.1 4.8 2 2 1 4 4 4 4 BNR repeat-like domain PSII_BNR PF14870.1 GAO86051.1 - 1.5e-08 34.0 5.1 0.00042 19.4 0.0 5.1 4 2 1 5 5 5 3 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 GAO86051.1 - 5e-07 28.5 47.9 0.033 13.9 1.1 9.3 9 0 0 9 9 9 6 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 GAO86051.1 - 0.047 13.4 5.8 2.5 7.9 0.2 3.2 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_tranf_2_3 PF13641.1 GAO86052.1 - 3e-22 79.5 0.0 4.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAO86052.1 - 3e-11 43.2 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAO86052.1 - 2.5e-07 30.1 0.2 4.7e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 21 4HBT_2 PF13279.1 GAO86054.1 - 5.9e-07 29.9 0.0 9.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Aldedh PF00171.17 GAO86055.1 - 2.6e-183 609.5 0.1 3.2e-183 609.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMN_dh PF01070.13 GAO86055.1 - 3.2e-116 388.0 0.0 1.1e-115 386.3 0.0 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAO86055.1 - 7.5e-05 21.7 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO86055.1 - 0.00034 19.6 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase LuxC PF05893.9 GAO86055.1 - 0.0015 17.3 0.0 0.0025 16.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) His_biosynth PF00977.16 GAO86055.1 - 0.011 15.0 0.0 0.13 11.5 0.0 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein Epimerase PF01370.16 GAO86056.1 - 7.5e-11 41.9 0.4 2.2e-07 30.5 0.1 2.8 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO86056.1 - 5.2e-10 38.9 0.3 1e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAO86056.1 - 6.9e-06 26.1 1.2 3e-05 24.1 0.7 2.1 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO86056.1 - 8e-06 24.7 0.2 0.00011 21.0 0.0 2.3 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAO86056.1 - 3.3e-05 24.1 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAO86056.1 - 0.00026 19.9 0.1 0.0016 17.4 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein DUF1673 PF07895.6 GAO86056.1 - 0.0046 16.5 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DapB_N PF01113.15 GAO86056.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 GAO86056.1 - 0.02 13.8 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Fungal_trans_2 PF11951.3 GAO86057.1 - 1.7e-42 145.3 1.8 2.4e-42 144.9 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 GAO86058.1 - 2.3e-61 206.9 0.0 2.6e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aa_trans PF01490.13 GAO86059.1 - 3.1e-42 144.5 34.3 3.9e-42 144.1 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IL32 PF15225.1 GAO86059.1 - 8.2 6.4 6.6 24 4.9 0.3 3.0 4 0 0 4 4 4 0 Interleukin 32 FAD_binding_4 PF01565.18 GAO86060.1 - 1.4e-11 43.9 4.0 6e-11 41.9 2.7 2.1 1 1 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.3 GAO86061.1 - 0.00017 20.2 1.1 0.00027 19.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 GAO86062.1 - 1.9e-13 50.6 0.0 3.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO86062.1 - 1.5e-06 27.9 0.1 2.2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAO86062.1 - 0.0099 14.8 0.1 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TPP_enzyme_C PF02775.16 GAO86062.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Lactamase_B PF00753.22 GAO86063.1 - 2.4e-07 30.6 1.2 7.9e-07 28.9 0.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO86063.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO86063.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SnoaL_2 PF12680.2 GAO86064.1 - 6.1e-05 23.3 0.2 8.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DAO PF01266.19 GAO86065.1 - 5e-50 170.4 0.1 6.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86065.1 - 2.2e-07 30.8 0.0 7.5e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO86065.1 - 7.9e-07 29.1 0.1 0.0014 18.5 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO86065.1 - 0.0011 19.1 0.1 0.0057 16.7 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO86065.1 - 0.0015 17.5 0.2 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAO86065.1 - 0.0017 18.1 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAO86065.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 GAO86065.1 - 0.015 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 GAO86065.1 - 0.016 14.0 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO86065.1 - 0.016 13.8 0.0 0.16 10.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 GAO86065.1 - 0.02 13.3 0.0 0.64 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 GAO86065.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 GAO86065.1 - 0.089 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 GAO86065.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Fungal_trans PF04082.13 GAO86066.1 - 9.1e-14 50.9 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3782 PF12644.2 GAO86066.1 - 0.17 11.6 0.0 1 9.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) NPP1 PF05630.6 GAO86067.1 - 7.3e-84 280.6 0.1 9.2e-84 280.3 0.1 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) CoA_transf_3 PF02515.12 GAO86069.1 - 6.7e-35 120.0 0.0 1.1e-31 109.6 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.13 GAO86070.1 - 1.1e-13 50.6 5.7 5.9e-08 31.8 0.4 3.1 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86070.1 - 7.5e-07 28.9 13.0 1.5e-06 28.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 GAO86071.1 - 6.3e-29 100.8 0.1 8.8e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO86071.1 - 2.4e-15 57.0 0.1 3.1e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO86071.1 - 0.0004 19.8 0.2 0.00086 18.8 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO86071.1 - 0.0014 17.3 0.0 0.003 16.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO86071.1 - 0.0035 17.2 0.5 0.0069 16.3 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAO86071.1 - 0.0036 16.3 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1341 PF07071.6 GAO86071.1 - 0.032 13.7 0.1 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) DapB_N PF01113.15 GAO86071.1 - 0.04 13.8 0.2 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus dCMP_cyt_deam_1 PF00383.17 GAO86072.1 - 3.2e-09 36.3 0.0 4.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MFS_1 PF07690.11 GAO86072.1 - 0.0003 19.6 0.7 0.00039 19.2 0.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Bd3614-deam PF14439.1 GAO86072.1 - 0.0052 16.6 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase Fungal_trans PF04082.13 GAO86073.1 - 4e-10 39.0 0.0 6.5e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86073.1 - 4e-08 33.0 11.9 7.9e-08 32.0 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 GAO86074.1 - 5.3e-15 56.4 0.0 1.3e-14 55.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO86074.1 - 5.5e-11 42.1 0.0 9.4e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAO86074.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding ELFV_dehydrog PF00208.16 GAO86074.1 - 0.061 12.8 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 GAO86074.1 - 0.12 12.3 1.2 0.13 12.1 0.3 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Cupin_2 PF07883.6 GAO86075.1 - 3.9e-09 35.8 0.0 5.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAO86075.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Ribonuc_L-PSP PF01042.16 GAO86076.1 - 1.6e-09 37.5 0.0 4e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 GAO86077.1 - 1.4e-17 63.4 0.0 2.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_2 PF00797.12 GAO86078.1 - 8.7e-43 146.6 0.5 3e-41 141.6 0.4 2.2 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 GAO86078.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Fer2 PF00111.22 GAO86079.1 - 3.1e-11 42.8 0.7 3.1e-11 42.8 0.5 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 GAO86079.1 - 0.00053 20.5 0.0 0.0034 17.9 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.1 GAO86079.1 - 0.013 15.3 0.1 0.034 13.9 0.1 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.1 GAO86079.1 - 0.071 12.9 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain 4HBT_3 PF13622.1 GAO86080.1 - 3.5e-23 82.6 5.4 8.8e-12 45.2 0.1 2.5 2 1 1 3 3 3 2 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAO86080.1 - 7e-11 41.8 0.1 7.9e-07 28.7 0.0 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase MFS_1 PF07690.11 GAO86081.1 - 5.7e-42 143.6 83.2 1.2e-37 129.4 40.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86081.1 - 5e-16 58.3 11.7 5e-16 58.3 8.1 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO86081.1 - 9.9e-15 53.7 10.2 9.9e-15 53.7 7.0 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 GAO86082.1 - 2e-44 151.8 0.0 2.7e-43 148.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.21 GAO86083.1 - 4.1e-70 236.1 0.0 8.1e-70 235.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAO86083.1 - 5.7e-61 206.2 0.3 9.5e-61 205.5 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAO86083.1 - 1.9e-60 204.8 0.5 6.9e-50 170.1 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.5 GAO86083.1 - 1.9e-60 203.6 0.3 6.7e-60 201.8 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAO86083.1 - 3.1e-46 157.3 0.2 1.3e-45 155.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO86083.1 - 6.9e-36 122.6 0.0 1.7e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO86083.1 - 3.5e-18 65.9 0.0 9.1e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO86083.1 - 9.4e-12 44.9 0.1 8.8e-11 41.7 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAO86083.1 - 1.4e-11 45.3 0.0 1.4e-10 42.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO86083.1 - 2.5e-10 40.0 0.0 1.1e-09 37.9 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 GAO86083.1 - 3.4e-08 33.8 0.0 1.3e-07 31.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 GAO86083.1 - 4.2e-08 32.9 0.2 1.2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAO86083.1 - 6.2e-08 32.7 0.3 1.7e-07 31.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 GAO86083.1 - 4.1e-07 29.6 0.0 1.3e-06 28.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86083.1 - 5.1e-06 27.0 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO86083.1 - 3.8e-05 23.6 0.0 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO86083.1 - 9.8e-05 22.6 0.0 0.00032 21.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAO86083.1 - 0.0021 16.8 0.0 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 GAO86083.1 - 0.0021 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAO86083.1 - 0.0046 15.9 0.4 0.0046 15.9 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain RrnaAD PF00398.15 GAO86083.1 - 0.029 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 GAO86083.1 - 0.032 13.6 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 GAO86083.1 - 0.038 13.3 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_72 PF03198.9 GAO86087.1 - 1.9e-133 444.3 10.9 2.4e-133 443.9 7.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAO86087.1 - 2.3e-23 82.4 4.0 2.3e-23 82.4 2.8 2.1 2 0 0 2 2 2 1 X8 domain DUF2406 PF10295.4 GAO86088.1 - 5e-22 78.1 1.0 5e-22 78.1 0.7 1.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DegT_DnrJ_EryC1 PF01041.12 GAO86089.1 - 2.9e-76 256.8 0.0 3.2e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAO86089.1 - 1.2e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAO86089.1 - 3.7e-07 29.2 0.0 8.9e-07 27.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAO86089.1 - 0.00087 18.5 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAO86089.1 - 0.0036 15.6 0.0 0.013 13.8 0.0 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_3 PF00933.16 GAO86090.1 - 4.6e-89 298.3 0.0 6.5e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO86090.1 - 5.1e-39 134.1 0.2 7.4e-38 130.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO86090.1 - 3.5e-19 68.5 0.0 7.4e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Nuc_sug_transp PF04142.10 GAO86091.1 - 2.3e-34 118.5 2.7 3.8e-34 117.8 1.9 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAO86091.1 - 1.7e-06 27.1 6.9 2.2e-06 26.8 4.8 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 GAO86091.1 - 0.00013 22.1 0.7 0.00013 22.1 0.5 2.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAO86091.1 - 0.022 14.7 0.9 0.022 14.7 0.6 3.3 3 1 0 3 3 3 0 EamA-like transporter family Gly_transf_sug PF04488.10 GAO86092.1 - 3.5e-12 46.6 0.0 1.1e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif PIG-L PF02585.12 GAO86093.1 - 6.8e-22 78.3 0.0 9.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CAP59_mtransfer PF11735.3 GAO86094.1 - 1.5e-81 273.2 0.0 1.9e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_3 PF13641.1 GAO86095.1 - 8.6e-26 91.1 0.0 1.5e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAO86095.1 - 1e-10 41.6 7.0 2.3e-10 40.5 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAO86095.1 - 4e-07 29.8 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Gly_transf_sug PF04488.10 GAO86095.1 - 9.2e-05 22.7 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_transf_21 PF13506.1 GAO86095.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 TcdA_TcdB PF12919.2 GAO86095.1 - 0.2 10.1 0.0 0.34 9.3 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PilM_2 PF11104.3 GAO86095.1 - 0.31 9.8 0.0 0.47 9.2 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Sugar_tr PF00083.19 GAO86096.1 - 1e-94 317.7 26.1 1.2e-94 317.4 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86096.1 - 2.7e-35 121.7 45.3 4e-32 111.3 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO86096.1 - 0.0089 15.8 9.4 0.18 11.6 0.1 4.2 3 1 1 4 4 4 2 MFS_1 like family DUF3317 PF11779.3 GAO86096.1 - 0.033 13.6 5.8 0.31 10.4 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) TRI12 PF06609.8 GAO86096.1 - 0.034 12.3 8.2 0.064 11.4 2.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ADH_N PF08240.7 GAO86097.1 - 3e-30 104.1 3.1 3.7e-30 103.8 0.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO86097.1 - 3.7e-24 84.7 0.0 6.2e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO86097.1 - 0.0029 18.4 0.0 0.0059 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO86097.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAO86097.1 - 0.039 13.7 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 GAO86097.1 - 0.046 13.9 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAO86097.1 - 0.1 12.1 0.1 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAO86097.1 - 0.22 9.9 0.4 0.33 9.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 GAO86098.1 - 2.4e-23 82.3 0.1 4.1e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 GAO86099.1 - 2.2e-26 92.0 0.5 2.9e-12 46.7 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86099.1 - 3.2e-17 61.3 0.5 3.8e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAO86099.1 - 6.8e-12 45.2 0.3 2.4e-06 27.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86099.1 - 3.4e-10 39.1 0.1 0.00046 20.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAO86099.1 - 3.4e-09 36.9 0.0 9.6e-05 22.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SGL PF08450.7 GAO86100.1 - 1.6e-06 27.7 0.2 0.0073 15.7 0.0 3.2 3 0 0 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 GAO86100.1 - 0.058 13.6 0.5 19 5.6 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain Glyco_hydro_28 PF00295.12 GAO86101.1 - 7.9e-113 376.6 21.4 9e-113 376.5 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sulf_transp PF04143.9 GAO86101.1 - 7.4 6.6 7.6 0.76 9.8 1.6 2.1 2 0 0 2 2 2 0 Sulphur transport Tri3 PF07428.6 GAO86102.1 - 0.00018 20.3 0.0 0.0013 17.4 0.0 2.0 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Glyco_hydro_7 PF00840.15 GAO86104.1 - 1.7e-207 689.0 26.1 1.7e-207 689.0 18.1 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAO86104.1 - 1.4e-13 50.2 13.1 1.4e-13 50.2 9.1 4.2 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAO86104.1 - 0.65 10.0 6.7 0.43 10.6 2.1 2.5 2 0 0 2 2 2 0 Toxin 7 Cellulase PF00150.13 GAO86105.1 - 6e-56 189.6 3.6 8.2e-56 189.2 2.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAO86105.1 - 5.6e-14 51.5 13.1 5.6e-14 51.5 9.1 2.8 4 0 0 4 4 4 1 Fungal cellulose binding domain MCR_alpha PF02249.12 GAO86105.1 - 0.016 15.1 2.9 0.016 15.1 2.0 2.7 2 1 1 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Zn_clus PF00172.13 GAO86106.1 - 3.5e-07 30.0 12.5 7.3e-07 29.0 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YpM PF09144.5 GAO86106.1 - 0.2 11.6 0.1 0.81 9.6 0.0 1.9 2 0 0 2 2 2 0 Yersinia pseudotuberculosis mitogen Methyltransf_23 PF13489.1 GAO86107.1 - 1.2e-20 73.8 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86107.1 - 3.1e-09 37.3 0.0 2e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86107.1 - 2.3e-07 30.5 0.0 8.6e-07 28.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86107.1 - 0.00013 22.3 0.0 0.00044 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAO86107.1 - 0.00058 18.9 0.0 0.18 10.8 0.0 2.7 2 1 1 3 3 3 2 Putative methyltransferase MTS PF05175.9 GAO86107.1 - 0.052 12.9 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 GAO86107.1 - 0.058 13.8 0.0 0.28 11.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAO86107.1 - 0.061 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GRAS PF03514.9 GAO86107.1 - 0.067 11.8 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family His_Phos_2 PF00328.17 GAO86109.1 - 1.3e-24 87.2 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 GAO86109.1 - 0.00021 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SKG6 PF08693.5 GAO86109.1 - 0.026 13.8 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FANCI_S3 PF14677.1 GAO86110.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 Na_H_Exchanger PF00999.16 GAO86111.1 - 3.3e-41 141.1 33.0 5.2e-41 140.4 22.9 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NAD_binding_10 PF13460.1 GAO86112.1 - 4.5e-10 39.8 0.2 6.3e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO86112.1 - 7.5e-06 25.3 0.2 1e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAO86112.1 - 0.00016 21.6 0.1 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Peripla_BP_4 PF13407.1 GAO86112.1 - 0.0038 16.6 0.2 0.0096 15.3 0.0 1.7 1 1 1 2 2 2 1 Periplasmic binding protein domain Epimerase PF01370.16 GAO86112.1 - 0.0097 15.3 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAO86112.1 - 0.021 14.5 0.1 0.072 12.7 0.0 1.8 1 1 1 2 2 2 0 KR domain PHO4 PF01384.15 GAO86113.1 - 1.4e-109 365.7 9.4 1.7e-109 365.4 6.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 GAO86113.1 - 0.00028 20.6 0.0 0.00099 18.8 0.0 1.9 1 0 0 1 1 1 1 Glycophorin A HTH_IclR PF09339.5 GAO86113.1 - 0.018 14.5 0.2 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain Adeno_E3_CR2 PF02439.10 GAO86113.1 - 0.046 13.2 0.0 2.4 7.7 0.1 2.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Claudin_2 PF13903.1 GAO86114.1 - 0.12 12.0 10.6 19 4.8 5.4 3.0 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF347 PF03988.7 GAO86114.1 - 1.2 9.0 0.0 1.2 9.0 0.0 4.1 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) Zn_clus PF00172.13 GAO86115.1 - 1e-05 25.3 11.7 2e-05 24.3 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OmdA PF13376.1 GAO86115.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Abhydrolase_6 PF12697.2 GAO86117.1 - 2.3e-34 119.2 1.1 2.9e-34 118.9 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86117.1 - 1.4e-12 47.5 1.1 3.2e-12 46.4 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86117.1 - 5.4e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAO86117.1 - 0.002 17.7 0.0 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF3089 PF11288.3 GAO86117.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.3 GAO86117.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) p450 PF00067.17 GAO86119.1 - 4.8e-52 177.0 0.0 7.5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_M PF02770.14 GAO86120.1 - 1.8e-05 24.1 0.0 3.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAO86120.1 - 0.049 13.7 0.1 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_8 PF01501.15 GAO86121.1 - 4.8e-30 104.6 0.0 6.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAO86121.1 - 6.9e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative BTB PF00651.26 GAO86122.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 GAO86123.1 - 0.0022 17.9 0.1 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 GAO86124.1 - 0.0017 18.2 0.0 0.0051 16.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_6 PF12697.2 GAO86126.1 - 2.6e-27 96.1 1.6 4.4e-27 95.4 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86126.1 - 3.2e-11 43.2 0.0 6.2e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO86126.1 - 3.3e-09 36.6 0.0 8.1e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO86126.1 - 7.7e-08 32.0 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_2 PF01674.13 GAO86126.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) MARVEL PF01284.18 GAO86127.1 - 2.1e-16 60.0 8.9 2.6e-16 59.7 6.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.3 GAO86127.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) peroxidase PF00141.18 GAO86128.1 - 3.5e-92 308.0 0.0 1.2e-48 165.6 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Acetyltransf_1 PF00583.19 GAO86129.1 - 1.9e-08 34.1 0.1 3.1e-08 33.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO86129.1 - 5.1e-08 32.9 0.0 1.5e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO86129.1 - 5.2e-07 29.8 0.1 2.4e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO86129.1 - 9.8e-05 22.2 0.1 0.00025 20.8 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO86129.1 - 0.0034 17.1 0.1 0.009 15.7 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAO86129.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase NAD_binding_10 PF13460.1 GAO86130.1 - 4.1e-21 75.8 0.0 5.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO86130.1 - 0.00013 21.3 0.0 0.00048 19.4 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 GAO86130.1 - 0.03 13.7 0.0 25 4.1 0.0 3.1 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family DUF4473 PF14747.1 GAO86130.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) PQQ_2 PF13360.1 GAO86131.1 - 0.042 13.3 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Beta-lactamase PF00144.19 GAO86132.1 - 1.3e-45 155.9 0.0 2.3e-45 155.0 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 GAO86133.1 - 3.9e-25 88.2 5.7 8.2e-25 87.2 3.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86133.1 - 3.7e-08 33.1 10.2 8.4e-08 31.9 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 GAO86134.1 - 3.8e-28 98.0 0.9 8.5e-28 96.9 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 GAO86135.1 - 5.9e-14 52.3 0.3 1.1e-13 51.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO86135.1 - 2.3e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO86135.1 - 5.5e-06 26.1 1.5 1.4e-05 24.8 1.0 1.7 1 1 0 1 1 1 1 KR domain DUF3929 PF13066.1 GAO86136.1 - 0.026 14.2 0.2 0.072 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) YqzH PF14164.1 GAO86137.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 YqzH-like protein Ank_2 PF12796.2 GAO86138.1 - 8.9e-62 205.4 0.4 2.1e-14 53.6 0.1 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86138.1 - 2.2e-46 153.3 9.7 1.3e-06 27.9 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 GAO86138.1 - 1.6e-40 136.7 3.5 4.1e-08 33.5 0.0 8.4 3 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86138.1 - 3.9e-38 128.6 10.1 4.9e-09 36.1 0.0 9.4 2 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86138.1 - 1.5e-35 117.6 2.7 0.00012 22.0 0.0 11.9 13 0 0 13 13 13 7 Ankyrin repeat CHAT PF12770.2 GAO86138.1 - 3.9e-30 104.9 0.4 7.7e-30 104.0 0.3 1.5 1 0 0 1 1 1 1 CHAT domain Tetrabrachion PF11401.3 GAO86138.1 - 0.096 12.4 1.3 0.51 10.1 0.1 2.4 2 0 0 2 2 2 0 Tetrabrachion adh_short PF00106.20 GAO86140.1 - 2.1e-05 24.4 0.0 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO86140.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 GAO86140.1 - 0.12 12.3 0.0 0.45 10.5 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Polyketide_cyc2 PF10604.4 GAO86141.1 - 2.6e-08 34.1 0.0 3e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 GAO86141.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 GAO86142.1 - 1.4e-09 38.2 0.0 1.7e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NmrA PF05368.8 GAO86143.1 - 4e-16 58.9 0.0 5.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO86143.1 - 6.1e-09 36.1 0.0 8.8e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO86143.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 GAO86144.1 - 0.00083 18.2 0.4 0.0023 16.8 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Codanin-1_C PF15296.1 GAO86144.1 - 0.049 13.4 0.1 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Codanin-1 C-terminus Calici_MSP PF05752.6 GAO86144.1 - 0.071 12.7 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein Polyketide_cyc2 PF10604.4 GAO86145.1 - 4.2e-16 59.3 0.0 4.8e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 GAO86145.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.20 GAO86146.1 - 0.00057 19.8 0.1 0.003 17.5 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase DUF4243 PF14027.1 GAO86147.1 - 5.7e-84 282.3 0.6 6.8e-84 282.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) adh_short PF00106.20 GAO86148.1 - 2e-10 40.8 0.1 8.2e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 GAO86148.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO86149.1 - 2.1e-22 79.8 0.1 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO86149.1 - 2.2e-13 50.2 0.1 3.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO86149.1 - 5e-09 36.2 0.1 7e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAO86149.1 - 3.3e-08 32.8 0.0 4.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAO86149.1 - 3.1e-05 23.5 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAO86149.1 - 4.5e-05 23.5 0.0 9e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAO86149.1 - 0.017 15.4 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.6 GAO86150.1 - 8.1e-33 113.5 0.1 1.7e-32 112.4 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAGSP PF03082.9 GAO86150.1 - 0.038 13.3 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Male accessory gland secretory protein TraG-D_C PF12696.2 GAO86150.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF1731 PF08338.6 GAO86150.1 - 0.12 11.8 0.0 7.3 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) BNR_2 PF13088.1 GAO86151.1 - 0.0066 15.7 0.2 0.98 8.6 0.0 2.1 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 GAO86151.1 - 0.027 14.2 0.8 0.027 14.2 0.6 4.0 5 0 0 5 5 5 0 BNR/Asp-box repeat GMC_oxred_N PF00732.14 GAO86152.1 - 8.8e-66 222.0 0.0 1.2e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO86152.1 - 1.8e-29 102.8 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAO86152.1 - 2.9e-05 23.1 0.2 0.00057 18.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86152.1 - 0.00022 21.1 0.0 0.00075 19.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO86152.1 - 0.00033 19.2 0.1 0.094 11.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 GAO86152.1 - 0.00081 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO86152.1 - 0.0022 16.9 0.1 0.019 13.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO86152.1 - 0.0042 17.1 0.2 0.56 10.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO86152.1 - 0.027 13.5 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 GAO86152.1 - 0.11 12.2 0.2 0.46 10.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Tannase PF07519.6 GAO86153.1 - 2.3e-76 257.4 0.0 2.8e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 GAO86153.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86153.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 GAO86154.1 - 8.5e-32 110.0 1.1 1.6e-31 109.1 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86154.1 - 8.9e-06 25.5 15.1 1.9e-05 24.4 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DMPK_coil PF08826.5 GAO86154.1 - 0.06 13.2 2.6 0.091 12.6 0.1 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF1446 PF07287.6 GAO86155.1 - 1.8e-128 428.0 0.2 2.1e-128 427.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) PUCC PF03209.10 GAO86155.1 - 0.85 8.2 4.3 1.3 7.6 3.0 1.2 1 0 0 1 1 1 0 PUCC protein MFS_1 PF07690.11 GAO86156.1 - 4.7e-31 107.7 30.9 4.7e-31 107.7 21.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.8 GAO86157.1 - 5.5e-28 97.7 0.0 1.1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family FAD_binding_4 PF01565.18 GAO86157.1 - 3.1e-27 94.7 8.4 2.4e-26 91.8 5.7 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_10 PF13460.1 GAO86157.1 - 1.5e-07 31.6 0.3 1e-06 28.9 0.1 2.3 2 1 1 3 3 3 2 NADH(P)-binding BBE PF08031.7 GAO86157.1 - 5.3e-07 29.4 0.3 1.9e-06 27.6 0.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like adh_short PF00106.20 GAO86157.1 - 0.0068 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase AMP-binding PF00501.23 GAO86158.1 - 8.7e-75 251.6 0.0 1.2e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO86158.1 - 3.4e-55 186.6 0.0 5.2e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAO86158.1 - 2.2e-12 47.0 0.0 4.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAO86158.1 - 4.1e-12 46.0 0.0 7.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO86158.1 - 1.1e-08 34.1 0.1 6.8e-08 31.5 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 GAO86158.1 - 0.035 15.0 0.0 0.14 13.1 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 GAO86159.1 - 2.1e-48 165.1 0.0 2.5e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO86159.1 - 0.0047 16.1 0.0 0.021 13.9 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_3 PF00202.16 GAO86159.1 - 0.14 10.9 0.0 0.32 9.7 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-III Glyoxalase_2 PF12681.2 GAO86160.1 - 0.079 13.5 0.3 7.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain Pyr_redox_2 PF07992.9 GAO86161.1 - 1.2e-14 54.6 2.0 1.5e-13 51.0 1.4 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO86161.1 - 4.7e-11 43.1 0.5 0.0081 16.2 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO86161.1 - 5.5e-10 39.5 0.1 4.7e-08 33.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO86161.1 - 9.5e-06 25.4 1.3 3.2 7.5 0.2 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAO86161.1 - 0.00025 20.0 0.0 0.35 9.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAO86161.1 - 0.0003 20.9 0.0 0.068 13.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAO86161.1 - 0.00081 19.5 0.1 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 GAO86161.1 - 0.0018 18.2 0.9 0.01 15.7 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Lycopene_cycl PF05834.7 GAO86161.1 - 0.0026 16.7 1.8 0.13 11.1 0.0 2.7 2 1 0 3 3 3 1 Lycopene cyclase protein KR PF08659.5 GAO86161.1 - 0.0067 16.1 1.5 0.018 14.6 0.2 2.2 3 0 0 3 3 3 1 KR domain GIDA PF01134.17 GAO86161.1 - 0.017 13.9 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 GAO86161.1 - 0.056 13.4 0.0 6 6.9 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 GAO86161.1 - 0.23 10.4 2.0 8.9 5.2 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.14 GAO86162.1 - 3e-30 105.4 0.0 1.6e-29 103.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO86162.1 - 1.9e-06 27.0 0.1 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86162.1 - 1.4e-05 24.9 0.1 4.7e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAO86162.1 - 7e-05 22.0 0.2 0.033 13.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAO86162.1 - 0.00033 20.9 0.4 0.0074 16.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO86162.1 - 0.00036 19.5 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAO86162.1 - 0.0068 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO86162.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAO86162.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAO86162.1 - 0.054 13.3 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO86162.1 - 0.086 11.6 0.1 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAO86162.1 - 0.2 10.0 0.0 0.44 8.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 GAO86163.1 - 4.2e-08 32.3 0.1 5.1e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain KNOX2 PF03791.8 GAO86163.1 - 0.062 12.5 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 KNOX2 domain DUF4037 PF13228.1 GAO86163.1 - 0.081 13.1 0.0 1.9 8.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4037) Str_synth PF03088.11 GAO86164.1 - 0.084 12.9 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Strictosidine synthase ADP_ribosyl_GH PF03747.9 GAO86165.1 - 3.8e-65 220.5 0.0 5.8e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Fungal_trans PF04082.13 GAO86165.1 - 3.7e-16 58.7 0.1 6.8e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.13 GAO86165.1 - 4.3e-15 55.8 0.0 1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_6 PF12697.2 GAO86166.1 - 4.7e-25 88.7 0.7 5.6e-25 88.5 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86166.1 - 6.2e-13 48.8 0.0 8.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO86166.1 - 5.8e-11 42.3 0.1 1.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAO86166.1 - 2.1e-08 34.6 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain MFS_1 PF07690.11 GAO86167.1 - 1.3e-29 103.0 40.6 1.3e-29 103.0 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 GAO86168.1 - 4.6e-43 147.6 0.0 6.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAO86169.1 - 1.8e-21 76.6 0.0 4.5e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO86169.1 - 3.1e-14 52.6 0.5 2.6e-06 26.5 0.2 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO86169.1 - 6.8e-07 29.3 0.0 1.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO86169.1 - 1.2e-06 27.2 2.1 0.00017 20.2 1.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 GAO86169.1 - 2.4e-06 27.8 2.2 0.011 16.1 1.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86169.1 - 1e-05 25.4 0.1 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO86169.1 - 1.9e-05 23.7 7.1 2.1e-05 23.5 3.9 1.6 1 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 GAO86169.1 - 3.3e-05 22.7 0.4 0.0091 14.6 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.2 GAO86169.1 - 0.0005 19.2 0.1 0.00066 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO86169.1 - 0.0011 19.0 0.2 0.0033 17.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO86169.1 - 0.0012 17.7 2.2 0.013 14.4 1.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 GAO86169.1 - 0.0016 17.3 3.0 0.0026 16.6 2.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAO86169.1 - 0.0032 17.1 0.7 0.0059 16.2 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 GAO86169.1 - 0.017 13.9 0.0 0.078 11.7 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 GAO86169.1 - 0.035 13.2 1.2 0.056 12.5 0.8 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 GAO86169.1 - 0.062 12.3 2.3 7.9 5.4 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 GAO86169.1 - 0.063 12.8 0.9 0.12 11.9 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cupin_2 PF07883.6 GAO86170.1 - 0.00028 20.3 1.6 0.0013 18.2 1.1 2.0 1 1 0 1 1 1 1 Cupin domain Methyltransf_2 PF00891.13 GAO86171.1 - 1.4e-30 106.2 0.0 2.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase ketoacyl-synt PF00109.21 GAO86172.1 - 8.3e-77 258.0 0.0 1.4e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO86172.1 - 2.7e-46 158.3 0.0 1.1e-44 153.0 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO86172.1 - 2e-33 114.7 0.2 4.2e-33 113.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO86172.1 - 1.6e-23 84.1 0.0 4.3e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAO86172.1 - 4.3e-21 74.9 3.2 8e-12 45.2 0.4 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAO86172.1 - 3.5e-19 69.0 0.1 7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 GAO86172.1 - 3.4e-09 36.9 0.8 1.4e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86172.1 - 1.8e-06 27.8 0.0 0.00087 19.0 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAO86172.1 - 8.7e-06 24.9 0.0 2.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAO86172.1 - 0.046 13.3 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2974 PF11187.3 GAO86172.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Fungal_trans PF04082.13 GAO86173.1 - 2e-19 69.5 0.6 3.4e-19 68.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 GAO86174.1 - 2.5e-61 206.9 0.0 3.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hemerythrin PF01814.18 GAO86175.1 - 1.6e-17 63.9 1.6 2.3e-17 63.4 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Spore_III_AB PF09548.5 GAO86175.1 - 0.29 10.8 1.9 0.59 9.8 0.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Pectinesterase PF01095.14 GAO86176.1 - 1.4e-123 411.2 82.1 1.6e-45 154.9 6.9 6.4 7 1 0 7 7 7 5 Pectinesterase DUF1788 PF08747.6 GAO86176.1 - 0.28 11.0 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) PNP_UDP_1 PF01048.15 GAO86178.1 - 2.2e-05 23.5 0.0 0.00011 21.2 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Ion_trans_2 PF07885.11 GAO86179.1 - 3.7e-18 64.9 3.6 3.7e-18 64.9 2.5 4.1 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.26 GAO86179.1 - 1.5e-07 30.8 11.8 2e-06 27.1 1.6 2.3 2 0 0 2 2 2 2 Ion transport protein AMP-binding PF00501.23 GAO86180.1 - 1.7e-51 174.9 0.0 2.3e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO86180.1 - 0.00029 21.7 0.0 0.00084 20.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.9 GAO86180.1 - 0.11 12.4 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 FeoA domain Fungal_trans PF04082.13 GAO86181.1 - 0.0017 17.2 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 GAO86182.1 - 3e-61 206.6 0.0 3.9e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 GAO86182.1 - 1.4e-07 31.8 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Glyoxalase_2 PF12681.2 GAO86183.1 - 7.5e-12 45.8 0.8 9.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 GAO86183.1 - 9.5e-09 35.3 6.2 4.6e-07 29.8 1.5 3.2 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2293 PF10056.4 GAO86183.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Glyoxalase_4 PF13669.1 GAO86183.1 - 0.018 15.0 0.2 0.25 11.3 0.1 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 GAO86184.1 - 6.6e-35 120.8 0.0 2.4e-34 118.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 GAO86184.1 - 5.1e-23 81.2 0.0 1.3e-22 79.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_C PF02752.17 GAO86184.1 - 5.5e-05 23.2 0.0 0.027 14.5 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAO86184.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DAO PF01266.19 GAO86185.1 - 1.9e-06 27.0 0.9 0.00082 18.3 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO86185.1 - 8.9e-06 25.8 0.0 0.00069 19.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86185.1 - 3.6e-05 23.6 0.0 9.8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO86185.1 - 0.0002 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAO86185.1 - 0.00034 19.7 0.1 0.11 11.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAO86185.1 - 0.00092 19.1 0.0 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO86185.1 - 0.011 16.1 0.1 0.061 13.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO86185.1 - 0.044 12.2 0.0 0.47 8.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 GAO86185.1 - 0.072 12.1 0.0 0.16 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.21 GAO86186.1 - 6.8e-10 38.5 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO86186.1 - 1.1e-08 34.7 0.0 7.7e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box PF00646.28 GAO86187.1 - 0.0043 16.6 0.3 0.014 15.0 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO86187.1 - 0.034 13.8 0.0 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like Glyco_hydro_47 PF01532.15 GAO86188.1 - 2.2e-162 540.8 0.0 2.5e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SAM_adeno_trans PF01887.11 GAO86188.1 - 0.042 12.8 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Glyco_hydro_18 PF00704.23 GAO86189.1 - 1.7e-96 323.6 9.1 2.1e-96 323.3 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.22 GAO86190.1 - 9.6e-34 114.9 2.3 1.4e-12 47.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3729 PF12526.3 GAO86190.1 - 0.069 14.4 0.2 11 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Glyco_hydro_15 PF00723.16 GAO86191.1 - 6.2e-50 170.0 0.0 1.1e-48 165.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Polyketide_cyc2 PF10604.4 GAO86192.1 - 0.00022 21.4 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2177 PF09945.4 GAO86194.1 - 0.94 9.4 7.6 0.12 12.3 0.9 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) CHAT PF12770.2 GAO86195.1 - 9.1e-37 126.7 0.0 2.1e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 CHAT domain SNAP PF14938.1 GAO86195.1 - 0.02 14.0 0.2 0.044 12.9 0.1 1.6 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Sugar_tr PF00083.19 GAO86197.1 - 2.7e-71 240.4 21.7 3.2e-71 240.2 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86197.1 - 6.7e-22 77.6 26.9 6.7e-22 77.6 18.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1395 PF07160.7 GAO86198.1 - 0.25 10.8 2.9 0.38 10.2 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) PAP2_3 PF14378.1 GAO86199.1 - 4.9e-18 65.3 13.8 2.5e-16 59.7 9.6 2.9 1 1 0 1 1 1 1 PAP2 superfamily Ferric_reduct PF01794.14 GAO86199.1 - 4.2e-17 62.4 15.8 4.2e-17 62.4 11.0 3.4 4 1 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAO86199.1 - 0.00017 21.3 0.0 0.00083 19.2 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAO86199.1 - 1.3 8.9 2.3 58 3.5 0.5 2.9 2 1 1 3 3 3 0 Ferric reductase NAD binding domain CVNH PF08881.5 GAO86200.1 - 1.1e-14 54.4 0.8 4.7e-12 46.0 0.3 2.6 1 1 2 3 3 3 2 CVNH domain Mnd1 PF03962.10 GAO86200.1 - 0.19 11.3 5.9 0.24 11.0 1.0 2.3 2 0 0 2 2 2 0 Mnd1 family DUF4470 PF14737.1 GAO86201.1 - 1.2e-25 89.1 0.0 2.2e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Abhydrolase_3 PF07859.8 GAO86201.1 - 1.1e-18 67.5 0.0 3.8e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO86201.1 - 8.8e-11 41.0 0.0 4.5e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 GAO86201.1 - 1.1e-05 25.4 1.3 1.7e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.7 GAO86201.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2186 PF09952.4 GAO86201.1 - 0.076 13.2 0.4 0.16 12.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) DUF2974 PF11187.3 GAO86201.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Beta-lactamase PF00144.19 GAO86202.1 - 2.8e-43 148.2 0.2 4.2e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAO86202.1 - 0.0058 15.9 0.1 0.075 12.2 0.0 2.5 3 0 0 3 3 3 1 D-alanyl-D-alanine carboxypeptidase DUF2156 PF09924.4 GAO86203.1 - 1e-25 90.2 0.0 1.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Herpes_LAMP2 PF06126.6 GAO86203.1 - 0.2 9.9 0.1 0.27 9.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Acetyltransf_1 PF00583.19 GAO86204.1 - 3.2e-10 39.8 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO86204.1 - 9e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAO86204.1 - 0.00016 21.8 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO86204.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 GAO86204.1 - 0.022 14.8 0.1 0.055 13.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO86204.1 - 0.077 13.1 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2023 PF09633.5 GAO86204.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Acetyltransf_9 PF13527.1 GAO86204.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 GAO86205.1 - 7.4e-09 35.3 12.2 1.3e-08 34.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO86205.1 - 2e-07 30.1 0.1 2.9e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 GAO86206.1 - 4e-83 279.1 0.0 5.4e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO86206.1 - 1.7e-10 41.6 0.0 5.1e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.11 GAO86206.1 - 0.038 13.8 1.5 0.094 12.5 1.0 1.7 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 ECH PF00378.15 GAO86207.1 - 3e-61 206.6 0.4 3.6e-61 206.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAO86207.1 - 0.0015 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 GAO86207.1 - 0.051 13.3 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Arrestin_N PF00339.24 GAO86208.1 - 1.7e-07 31.1 0.0 4.2e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PIG-X PF08320.7 GAO86209.1 - 3.3e-26 91.8 0.0 3.5e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 FAD_binding_4 PF01565.18 GAO86210.1 - 1.2e-19 70.1 1.7 2.5e-19 69.1 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO86210.1 - 1e-08 34.9 0.8 2.2e-08 33.8 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.19 GAO86211.1 - 1.8e-95 320.1 24.1 2.2e-95 319.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86211.1 - 3e-25 88.6 48.8 1.5e-22 79.8 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Iso_dh PF00180.15 GAO86212.1 - 1e-88 297.6 0.0 1.3e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1400 PF07176.6 GAO86212.1 - 0.056 13.3 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Fungal_trans PF04082.13 GAO86213.1 - 2.9e-21 75.5 0.5 5e-21 74.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAO86215.1 - 5.6e-08 31.9 0.2 5.1e-07 28.8 0.0 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Melibiase PF02065.13 GAO86216.1 - 2.7e-161 536.6 0.0 3.5e-161 536.3 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 GAO86216.1 - 0.00057 18.8 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 PIG-L PF02585.12 GAO86217.1 - 6e-16 59.1 0.1 1.6e-15 57.7 0.1 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cerato-platanin PF07249.7 GAO86217.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Cerato-platanin DUF1275 PF06912.6 GAO86218.1 - 4.8e-33 114.1 16.5 6e-33 113.7 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Melibiase PF02065.13 GAO86219.1 - 5.6e-38 130.6 0.1 7.8e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Thioredoxin PF00085.15 GAO86220.1 - 3.5e-27 94.1 0.0 4.1e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAO86220.1 - 5.9e-09 36.1 0.1 1.4e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 GAO86220.1 - 4.9e-06 26.1 0.1 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 GAO86220.1 - 5.1e-06 26.5 0.0 0.00017 21.6 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 GAO86220.1 - 6.5e-05 22.6 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 GAO86220.1 - 0.0004 19.9 0.0 0.00047 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAO86220.1 - 0.00077 19.4 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 GAO86220.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Pyr_redox_2 PF07992.9 GAO86221.1 - 5.1e-13 49.3 0.0 1e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO86221.1 - 9.7e-11 41.9 1.2 9.3e-09 35.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO86221.1 - 4.6e-06 26.8 4.4 0.11 12.5 0.4 3.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO86221.1 - 0.0041 16.9 0.9 49 3.6 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Glyoxalase PF00903.20 GAO86222.1 - 2.3e-11 43.7 0.0 3.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO86222.1 - 9.9e-08 32.5 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain DUF3430 PF11912.3 GAO86223.1 - 0.022 14.5 2.0 0.022 14.5 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3430) CVNH PF08881.5 GAO86223.1 - 0.068 13.3 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 CVNH domain FA_hydroxylase PF04116.8 GAO86224.1 - 2e-15 57.2 24.0 1e-14 54.8 15.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GST_C PF00043.20 GAO86225.1 - 3.3e-10 39.8 0.1 9.7e-10 38.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO86225.1 - 2.7e-08 33.5 0.0 7.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO86225.1 - 4.4e-07 29.9 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO86225.1 - 0.00072 19.9 0.1 0.0033 17.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain OTT_1508_deam PF14441.1 GAO86225.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF2069 PF09842.4 GAO86226.1 - 0.0025 17.7 3.1 0.0025 17.7 2.2 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2069) Tetraspannin PF00335.15 GAO86226.1 - 0.054 12.7 0.0 0.054 12.7 0.0 2.5 2 1 0 2 2 2 0 Tetraspanin family CRPA PF05745.6 GAO86226.1 - 0.29 10.9 6.1 0.43 10.3 3.4 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1430 PF07242.6 GAO86226.1 - 7.8 6.6 13.7 0.47 10.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Apolipoprotein PF01442.13 GAO86227.1 - 0.00072 19.1 2.8 0.0012 18.4 1.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DIT1_PvcA PF05141.7 GAO86227.1 - 0.047 12.9 1.5 0.08 12.2 1.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Fzo_mitofusin PF04799.8 GAO86227.1 - 0.086 12.2 1.0 0.19 11.1 0.7 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF883 PF05957.8 GAO86227.1 - 0.19 12.1 1.0 0.46 10.9 0.7 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SBP_bac_7 PF03480.8 GAO86227.1 - 0.48 9.4 5.4 1 8.3 2.3 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 YtxH PF12732.2 GAO86227.1 - 1.1 9.6 2.6 3 8.2 1.8 1.8 1 1 0 1 1 1 0 YtxH-like protein Asp PF00026.18 GAO86229.1 - 4.4e-58 196.9 4.3 5.7e-58 196.6 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAO86229.1 - 1.6e-06 28.1 1.0 5.8e-06 26.3 0.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAO86229.1 - 5.9e-06 25.9 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Herpes_V23 PF01802.12 GAO86229.1 - 0.25 10.3 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein FA_desaturase PF00487.19 GAO86230.1 - 5.3e-37 127.6 33.0 7.4e-37 127.1 22.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAO86230.1 - 3.8e-12 45.8 0.0 8.3e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ham1p_like PF01725.11 GAO86231.1 - 3.3e-35 121.1 0.0 3.7e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3129 PF11327.3 GAO86232.1 - 1.3e-76 256.5 9.6 1.6e-76 256.2 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Trp_DMAT PF11991.3 GAO86233.1 - 1.1e-100 337.3 0.0 1.3e-100 337.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase PIG-L PF02585.12 GAO86234.1 - 2.8e-13 50.4 0.0 9.1e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 GAO86235.1 - 3.2e-06 27.4 0.0 8.1e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAO86235.1 - 0.0035 15.9 0.0 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_25 PF01755.12 GAO86236.1 - 2.2e-06 27.4 0.0 0.045 13.3 0.0 2.4 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) UCR_Fe-S_N PF10399.4 GAO86236.1 - 0.1 11.7 0.1 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal UAA PF08449.6 GAO86237.1 - 0.00069 18.6 5.2 0.00088 18.2 3.6 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 GAO86237.1 - 0.021 13.9 0.6 0.021 13.9 0.4 1.5 2 0 0 2 2 2 0 Nucleotide-sugar transporter TPT PF03151.11 GAO86237.1 - 0.14 11.7 11.9 0.62 9.7 0.3 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 GAO86237.1 - 0.93 9.7 16.5 0.07 13.3 4.0 2.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter TPT PF03151.11 GAO86238.1 - 5.7e-21 74.7 14.1 5.7e-21 74.7 9.8 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family Gly_transf_sug PF04488.10 GAO86238.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif UAA PF08449.6 GAO86238.1 - 9.6e-06 24.7 20.1 2.6e-05 23.2 13.9 1.6 1 1 0 1 1 1 1 UAA transporter family TcdA_TcdB PF12919.2 GAO86238.1 - 0.11 10.9 2.1 0.55 8.6 0.1 2.5 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain EamA PF00892.15 GAO86238.1 - 6 6.9 34.9 0.27 11.2 5.3 3.5 4 0 0 4 4 4 0 EamA-like transporter family Glyco_tranf_2_3 PF13641.1 GAO86239.1 - 1.4e-35 123.2 0.1 2.1e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAO86239.1 - 2.9e-19 69.5 0.3 2.9e-19 69.5 0.2 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAO86239.1 - 1.2e-12 47.8 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAO86239.1 - 7.4e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 GAO86239.1 - 0.0092 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 GAO86239.1 - 0.017 13.4 0.2 0.26 9.5 0.0 2.1 1 1 1 2 2 2 0 Cellulose synthase Glyco_hydro_18 PF00704.23 GAO86240.1 - 4.4e-21 75.7 6.9 2.8e-20 73.0 1.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF4434 PF14488.1 GAO86240.1 - 0.011 15.4 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) MiAMP1 PF09117.5 GAO86241.1 - 1.1e-05 25.7 1.8 1.6e-05 25.1 1.2 1.2 1 0 0 1 1 1 1 MiAMP1 FmdE PF02663.9 GAO86241.1 - 0.05 13.4 0.1 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Aa_trans PF01490.13 GAO86242.1 - 4.9e-41 140.5 36.1 5.9e-41 140.2 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ppx-GppA PF02541.11 GAO86243.1 - 1.6e-35 122.7 0.0 3.1e-35 121.7 0.0 1.4 1 1 0 1 1 1 1 Ppx/GppA phosphatase family p450 PF00067.17 GAO86244.1 - 5.5e-144 480.1 0.0 3.6e-73 246.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 GAO86244.1 - 1.9e-10 40.0 1.9 5.2e-10 38.6 0.9 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO86245.1 - 8.7e-41 139.9 15.6 1.2e-40 139.4 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86245.1 - 3.7e-36 124.5 27.4 5.6e-36 123.9 17.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 GAO86245.1 - 1.1e-06 27.3 1.6 1.1e-06 27.3 1.1 2.3 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 GAO86245.1 - 0.00043 20.0 0.8 0.0042 16.8 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family DUF3180 PF11377.3 GAO86245.1 - 0.033 14.0 6.7 0.048 13.5 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3180) HTH_38 PF13936.1 GAO86245.1 - 0.061 12.8 0.4 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Ald_Xan_dh_C2 PF02738.13 GAO86246.1 - 9.3e-182 605.1 0.0 1.2e-181 604.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAO86246.1 - 1.4e-40 138.5 0.3 2.6e-40 137.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 GAO86246.1 - 7.3e-33 112.5 0.0 7.3e-32 109.3 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 GAO86246.1 - 5e-25 87.1 0.0 1.3e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 GAO86246.1 - 1.9e-24 85.8 0.1 3.7e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 GAO86246.1 - 2.3e-07 30.4 0.0 2.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_3 PF01494.14 GAO86247.1 - 6.9e-76 255.6 0.0 8.5e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO86247.1 - 1.1e-37 129.2 0.0 1.7e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 GAO86247.1 - 5.5e-06 26.5 0.1 2.3e-05 24.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86247.1 - 9.2e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO86247.1 - 2.6e-05 23.3 0.4 0.00018 20.5 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO86247.1 - 4.4e-05 22.1 0.1 8.1e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 GAO86247.1 - 0.00017 21.9 0.0 0.00054 20.3 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO86247.1 - 0.0011 18.8 0.0 0.0049 16.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO86247.1 - 0.0014 17.6 0.2 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAO86247.1 - 0.0024 16.9 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAO86247.1 - 0.017 13.9 0.1 0.034 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAO86247.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAO86247.1 - 0.034 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 GAO86247.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 GAO86247.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 GAO86247.1 - 0.23 10.2 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAO86248.1 - 2.6e-11 43.2 0.1 4.6e-10 39.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO86248.1 - 6.5e-09 35.1 3.1 0.0018 17.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAO86248.1 - 8.6e-08 31.2 2.0 0.0056 15.3 0.3 2.3 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 GAO86248.1 - 2.1e-05 23.1 0.5 0.00011 20.8 0.3 1.8 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAO86248.1 - 0.00011 22.1 3.0 0.00017 21.5 0.9 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO86248.1 - 0.0005 19.0 5.4 0.0011 17.9 3.0 2.0 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 GAO86248.1 - 0.0019 17.3 0.6 0.0038 16.3 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO86248.1 - 0.0023 16.9 0.4 0.0061 15.5 0.3 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAO86248.1 - 0.013 15.5 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO86248.1 - 0.021 14.4 0.2 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 GAO86248.1 - 0.036 13.9 0.6 0.065 13.0 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAO86248.1 - 0.048 13.3 0.7 0.083 12.5 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAO86248.1 - 0.12 12.7 0.5 0.61 10.5 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO86248.1 - 0.12 11.1 4.3 0.18 10.5 3.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAO86248.1 - 0.76 9.5 2.9 2 8.1 1.0 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding AAA PF00004.24 GAO86249.1 - 1.7e-17 63.8 0.0 1.2e-06 28.7 0.0 4.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO86249.1 - 1e-11 45.0 1.1 0.032 14.3 0.0 5.5 3 2 1 4 4 4 3 AAA domain Sigma54_activ_2 PF14532.1 GAO86249.1 - 2.4e-09 37.3 0.0 0.03 14.3 0.0 3.9 4 0 0 4 4 3 2 Sigma-54 interaction domain Torsin PF06309.6 GAO86249.1 - 2.4e-08 33.9 0.0 0.43 10.4 0.0 3.5 3 0 0 3 3 3 3 Torsin AAA_17 PF13207.1 GAO86249.1 - 3.1e-08 34.4 0.1 0.0051 17.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAO86249.1 - 3e-07 30.3 0.0 0.00016 21.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAO86249.1 - 6e-07 29.2 0.1 0.11 12.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO86249.1 - 6.7e-07 29.4 3.6 0.017 15.1 0.4 4.5 3 2 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 GAO86249.1 - 2.7e-06 27.0 0.3 0.083 12.6 0.0 3.8 4 0 0 4 4 2 2 Part of AAA domain RuvB_N PF05496.7 GAO86249.1 - 8.2e-06 25.0 0.0 0.16 11.0 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 GAO86249.1 - 0.00011 21.7 0.0 2.9 7.3 0.0 4.2 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.1 GAO86249.1 - 0.00015 22.0 0.2 0.33 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAO86249.1 - 0.00021 20.5 0.0 0.12 11.5 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAO86249.1 - 0.0015 18.5 1.4 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 GAO86249.1 - 0.0015 18.1 0.2 3.1 7.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 GAO86249.1 - 0.0044 16.7 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 GAO86249.1 - 0.015 14.7 0.0 2.6 7.6 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 GAO86249.1 - 0.018 14.4 0.0 2.7 7.3 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 GAO86249.1 - 0.027 14.0 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAO86249.1 - 0.028 14.6 0.0 4.9 7.3 0.0 2.8 3 0 0 3 3 2 0 RNA helicase DUF1757 PF08560.5 GAO86249.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) ABC_tran PF00005.22 GAO86249.1 - 0.033 14.4 0.1 6.4 7.0 0.0 3.0 3 0 0 3 3 2 0 ABC transporter AAA_10 PF12846.2 GAO86249.1 - 0.094 12.1 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain Thymidylate_kin PF02223.12 GAO86249.1 - 0.098 12.0 0.1 0.93 8.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase TIP49 PF06068.8 GAO86249.1 - 0.15 10.7 0.3 4.9 5.7 0.2 3.1 2 1 1 3 3 3 0 TIP49 C-terminus AA_permease PF00324.16 GAO86250.1 - 1.5e-113 379.7 43.3 1.7e-113 379.4 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO86250.1 - 3.6e-35 121.3 50.1 4.5e-35 121.0 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease CBM-like PF14683.1 GAO86251.1 - 6e-38 130.1 0.0 1.8e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 GAO86251.1 - 1.6e-23 82.6 0.1 1.6e-23 82.6 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 GAO86251.1 - 1.2e-10 41.3 0.9 7.1e-09 35.6 0.3 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 GAO86251.1 - 1.5e-05 24.9 0.0 8.4e-05 22.5 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4480) DUF4198 PF10670.4 GAO86251.1 - 0.00025 21.0 0.2 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4198) phage_tail_N PF08400.5 GAO86251.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Cna_B PF05738.8 GAO86251.1 - 0.099 12.4 1.2 0.23 11.2 0.2 2.0 2 0 0 2 2 2 0 Cna protein B-type domain AA_permease_2 PF13520.1 GAO86253.1 - 6.1e-47 160.1 54.6 7.2e-47 159.8 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO86253.1 - 3.2e-25 88.4 51.6 4.1e-25 88.0 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease Antimicrobial10 PF08105.6 GAO86253.1 - 0.0019 17.7 0.3 0.094 12.3 0.0 3.1 2 0 0 2 2 2 1 Metchnikowin family GAPT PF11770.3 GAO86253.1 - 0.2 11.3 0.6 1.8 8.2 0.6 2.1 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Amidohydro_2 PF04909.9 GAO86254.1 - 7e-09 35.6 0.0 8.5e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAO86254.1 - 0.00045 20.3 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAO86254.1 - 0.00085 19.0 0.1 0.0025 17.5 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Epimerase PF01370.16 GAO86255.1 - 6e-20 71.6 0.0 1.4e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO86255.1 - 4.6e-11 43.0 0.0 5.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO86255.1 - 9.9e-10 37.5 0.0 1.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAO86255.1 - 8.2e-05 21.6 0.0 0.00028 19.8 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 GAO86255.1 - 0.0006 19.1 0.2 0.0012 18.1 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAO86255.1 - 0.0026 16.7 0.8 0.0072 15.2 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO86255.1 - 0.02 13.7 0.3 0.039 12.8 0.2 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.19 GAO86256.1 - 3.3e-91 306.1 21.2 3.9e-91 305.8 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86256.1 - 4e-25 88.2 30.1 2e-22 79.3 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO86256.1 - 0.00012 20.4 0.3 0.00025 19.4 0.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Apc5 PF12862.2 GAO86256.1 - 0.13 12.0 0.0 1.7 8.5 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Spherulin4 PF12138.3 GAO86257.1 - 3.2e-61 206.9 0.1 4e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 FSH1 PF03959.8 GAO86258.1 - 4.9e-25 88.2 0.0 5.6e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAO86258.1 - 2.6e-07 30.4 0.0 4.3e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UDPG_MGDP_dh_N PF03721.9 GAO86259.1 - 1.4e-34 119.0 0.0 1.3e-22 80.0 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 GAO86259.1 - 1.1e-21 77.0 0.0 3.8e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 GAO86259.1 - 2.8e-09 37.0 0.0 6.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_9 PF13454.1 GAO86259.1 - 0.00044 20.0 0.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAO86259.1 - 0.0042 16.8 0.5 0.088 12.5 0.0 3.1 3 1 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 GAO86259.1 - 0.0053 16.1 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 GAO86259.1 - 0.021 13.8 0.2 0.095 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 GAO86259.1 - 0.047 13.7 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_75 PF07335.6 GAO86260.1 - 1.3e-48 164.8 0.2 1.6e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 MFS_1 PF07690.11 GAO86261.1 - 7.7e-40 136.6 53.3 2.3e-39 135.1 34.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 GAO86262.1 - 6.3e-36 123.8 0.0 7.6e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 GAO86263.1 - 0.0014 17.3 1.0 0.0014 17.3 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86263.1 - 0.0032 17.3 10.1 0.006 16.4 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PilJ PF13675.1 GAO86263.1 - 0.047 14.0 1.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ank_2 PF12796.2 GAO86264.1 - 9.9e-61 202.0 1.3 6.6e-21 74.4 0.3 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86264.1 - 3.7e-55 181.1 5.3 2.9e-07 29.9 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 GAO86264.1 - 2.3e-40 132.5 1.9 0.00074 19.5 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAO86264.1 - 2.7e-38 129.6 5.3 3.1e-09 37.0 0.0 7.3 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86264.1 - 2.5e-35 119.6 7.1 1.2e-10 41.2 0.2 7.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Acyl-CoA_dh_2 PF08028.6 GAO86265.1 - 7.1e-20 71.6 0.1 7.1e-20 71.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO86265.1 - 5.7e-08 33.3 0.1 1.1e-07 32.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 GAO86265.1 - 2.8e-05 24.2 1.4 0.0011 19.0 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.6 GAO86266.1 - 1.8e-30 105.8 0.0 3.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1681 PF07933.9 GAO86266.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Abhydrolase_6 PF12697.2 GAO86268.1 - 4.6e-22 79.0 1.2 7.1e-22 78.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86268.1 - 1.8e-10 40.7 0.0 3.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO86268.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAO86268.1 - 0.0001 21.6 0.0 0.00028 20.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 GAO86268.1 - 0.0003 20.4 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAO86268.1 - 0.078 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 GAO86268.1 - 0.14 11.8 0.1 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 GAO86268.1 - 0.2 11.0 0.3 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 Putative esterase DUF3789 PF12664.2 GAO86268.1 - 8.8 5.7 6.6 4.4 6.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) p450 PF00067.17 GAO86269.1 - 1.4e-50 172.2 0.0 1.8e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 GAO86270.1 - 4.7e-11 42.6 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86270.1 - 0.0096 15.5 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86270.1 - 0.025 15.0 0.0 0.16 12.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 GAO86271.1 - 7.9e-81 271.5 0.1 1.5e-80 270.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAO86271.1 - 1.3e-70 237.7 0.0 2.6e-70 236.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO86271.1 - 7.4e-51 173.3 0.0 2.2e-50 171.8 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 GAO86271.1 - 1.3e-50 171.5 0.0 1e-48 165.4 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAO86271.1 - 1.3e-47 162.3 0.0 2.8e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 GAO86271.1 - 5.4e-47 160.0 0.7 1e-46 159.1 0.5 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 GAO86271.1 - 2.4e-46 157.6 0.4 6.7e-40 136.7 0.0 4.4 4 0 0 4 4 4 2 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO86271.1 - 9.2e-38 129.5 0.0 5e-37 127.1 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAO86271.1 - 5.6e-31 106.8 0.1 1.9e-30 105.1 0.1 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO86271.1 - 1.5e-19 69.9 0.5 3.4e-12 46.4 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 GAO86271.1 - 2e-14 53.6 0.0 3.2e-11 43.1 0.0 3.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 GAO86271.1 - 8.7e-09 35.5 0.0 2.8e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 GAO86271.1 - 2.9e-06 26.2 0.1 0.00071 18.3 0.0 2.7 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 GAO86271.1 - 4.1e-06 27.6 1.2 1.4e-05 25.9 0.0 2.7 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 GAO86271.1 - 7.4e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 GAO86271.1 - 0.00012 22.6 0.0 0.001 19.6 0.0 2.8 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 GAO86271.1 - 0.00067 18.9 0.0 0.5 9.5 0.0 2.5 2 0 0 2 2 2 2 NmrA-like family Methyltransf_25 PF13649.1 GAO86271.1 - 0.0026 18.0 0.0 0.01 16.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAO86271.1 - 0.0039 16.1 0.5 0.17 10.7 0.0 3.0 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAO86271.1 - 0.0066 16.7 0.0 5.1 7.4 0.0 2.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 GAO86271.1 - 0.027 14.9 0.0 0.081 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 GAO86271.1 - 0.073 13.1 0.0 3.1 7.9 0.0 3.3 4 0 0 4 4 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 GAO86272.1 - 2.8e-10 40.4 0.4 5e-10 39.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86272.1 - 3.1e-09 36.7 0.0 2.2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86272.1 - 9e-05 22.1 0.2 0.0016 18.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 GAO86272.1 - 0.00041 19.0 0.0 0.00061 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAO86272.1 - 0.0058 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 GAO86272.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 Putative esterase DLH PF01738.13 GAO86272.1 - 0.062 12.5 0.0 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 GAO86272.1 - 0.1 11.1 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.23 GAO86273.1 - 6.8e-77 258.6 0.0 8.8e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.17 GAO86273.1 - 5.2e-67 226.3 0.0 7.1e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding_C PF13193.1 GAO86273.1 - 3.6e-15 56.6 0.2 2e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KR PF08659.5 GAO86274.1 - 5.2e-49 166.3 0.0 1e-48 165.3 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAO86274.1 - 4.5e-43 147.4 0.0 6.6e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAO86274.1 - 1.2e-38 132.6 0.0 2.2e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_18 PF12847.2 GAO86274.1 - 0.012 16.2 0.0 0.039 14.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain PhyH PF05721.8 GAO86275.1 - 1.1e-22 81.1 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4188 PF13826.1 GAO86276.1 - 1.5e-31 108.9 0.3 1.9e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 GAO86276.1 - 0.0018 17.3 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Peptidase_M24 PF00557.19 GAO86277.1 - 3.1e-42 144.5 0.0 3.9e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAO86277.1 - 0.00068 19.4 8.5 0.0017 18.1 5.9 1.7 1 0 0 1 1 1 1 MYND finger DUF2269 PF10027.4 GAO86278.1 - 0.034 13.9 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF1772 PF08592.6 GAO86278.1 - 0.067 12.9 0.4 0.13 11.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Pyr_redox_3 PF13738.1 GAO86279.1 - 1.8e-24 86.9 0.0 3.7e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.7 GAO86279.1 - 5.5e-19 68.4 0.0 1.4e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FMO-like PF00743.14 GAO86279.1 - 4.6e-16 58.1 0.0 8.3e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Methyltransf_23 PF13489.1 GAO86279.1 - 1.5e-15 57.2 0.0 3.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86279.1 - 6.6e-10 38.7 0.0 2.5e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86279.1 - 1.3e-08 35.3 0.0 4.6e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO86279.1 - 1.5e-08 35.0 0.0 4.3e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_8 PF13450.1 GAO86279.1 - 4.4e-07 29.8 0.0 2.3e-05 24.3 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAO86279.1 - 1.3e-05 24.3 0.0 4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_16 PF10294.4 GAO86279.1 - 1.5e-05 24.5 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 GAO86279.1 - 7e-05 22.0 0.0 0.00018 20.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pyr_redox_2 PF07992.9 GAO86279.1 - 0.0006 19.7 0.0 0.042 13.7 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO86279.1 - 0.0013 18.5 1.3 0.95 9.2 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Methyltransf_26 PF13659.1 GAO86279.1 - 0.0063 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 GAO86279.1 - 0.01 16.2 0.1 2.3 8.6 0.0 3.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO86279.1 - 0.012 14.5 0.3 0.81 8.5 0.1 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAO86279.1 - 0.022 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAO86279.1 - 0.025 13.5 0.1 1.4 7.7 0.1 2.9 2 1 0 2 2 2 0 Lycopene cyclase protein DREV PF05219.7 GAO86279.1 - 0.048 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 GAO86279.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase EthD PF07110.6 GAO86280.1 - 5.4e-15 56.0 0.5 7.4e-15 55.6 0.4 1.2 1 0 0 1 1 1 1 EthD domain Mannitol_dh_C PF08125.8 GAO86280.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain Med12 PF09497.5 GAO86281.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 Peptidase_M24 PF00557.19 GAO86282.1 - 7.4e-38 130.2 0.0 9.9e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_2 PF00891.13 GAO86283.1 - 1.5e-26 93.1 0.0 6.1e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Abhydrolase_6 PF12697.2 GAO86284.1 - 3.8e-15 56.4 0.0 4.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86284.1 - 2.3e-12 46.9 0.0 3.5e-12 46.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO86284.1 - 2.9e-08 33.1 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 GAO86284.1 - 4.6e-07 29.7 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAO86284.1 - 1e-05 25.1 0.0 2.3e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAO86284.1 - 1.1e-05 24.1 0.0 0.0021 16.6 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 GAO86284.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAO86284.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family ketoacyl-synt PF00109.21 GAO86285.1 - 6.4e-63 212.5 0.3 1.4e-62 211.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAO86285.1 - 4.5e-50 169.8 0.0 1e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAO86285.1 - 1.3e-49 169.0 0.0 2.1e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAO86285.1 - 1.8e-49 168.8 0.5 3e-49 168.0 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAO86285.1 - 3.1e-33 115.0 0.3 8.1e-33 113.6 0.2 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO86285.1 - 3.8e-31 107.4 0.0 1.2e-30 105.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO86285.1 - 1.3e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 GAO86285.1 - 1.6e-07 30.9 0.0 1e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO86285.1 - 2.1e-07 31.8 0.0 4.7e-06 27.5 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO86285.1 - 4.3e-05 23.2 0.4 0.00011 21.8 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAO86285.1 - 0.043 12.8 0.4 0.34 9.8 0.0 2.2 2 0 0 2 2 2 0 Thiolase, N-terminal domain SH3_3 PF08239.6 GAO86286.1 - 0.00047 20.2 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.14 GAO86286.1 - 0.0033 17.1 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 NlpC/P60 family TPR_19 PF14559.1 GAO86287.1 - 5.2e-07 29.9 10.2 0.00022 21.5 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAO86287.1 - 9.6e-06 25.7 0.6 0.00019 21.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 GAO86287.1 - 0.00023 20.8 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 GAO86287.1 - 0.00027 21.0 0.0 0.0035 17.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO86287.1 - 0.00028 20.3 0.1 0.0015 18.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain TPR_8 PF13181.1 GAO86287.1 - 0.00032 20.2 8.1 0.25 11.1 0.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA PF00004.24 GAO86287.1 - 0.00065 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAO86287.1 - 0.0012 18.5 0.0 0.004 16.8 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 GAO86287.1 - 0.0012 18.3 0.0 0.61 9.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAO86287.1 - 0.0024 17.3 0.0 0.0098 15.3 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_11 PF13414.1 GAO86287.1 - 0.0043 16.6 9.1 0.15 11.6 0.2 3.7 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 GAO86287.1 - 0.0074 16.0 10.3 1 9.3 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86287.1 - 0.013 15.4 10.5 1.3 8.9 0.4 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat NTPase_1 PF03266.10 GAO86287.1 - 0.016 14.9 0.0 0.048 13.3 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 GAO86287.1 - 0.016 14.9 0.2 0.12 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAO86287.1 - 0.063 14.0 1.6 1.1 10.1 0.0 3.7 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAO86287.1 - 0.07 13.4 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 GAO86287.1 - 0.072 13.1 0.3 1 9.4 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain TPR_16 PF13432.1 GAO86287.1 - 1.2 9.8 6.8 17 6.2 0.1 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO86287.1 - 3.5 7.7 7.8 14 5.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.17 GAO86288.1 - 1e-68 232.0 0.0 1.2e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lyase_aromatic PF00221.14 GAO86289.1 - 4.9e-161 536.3 4.2 6.1e-161 536.0 2.9 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Cupin_2 PF07883.6 GAO86290.1 - 9.9e-08 31.3 0.3 1.6e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.16 GAO86291.1 - 1.8e-15 57.0 0.1 4.5e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO86291.1 - 1.5e-11 43.5 0.0 2.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO86291.1 - 1.9e-06 28.0 0.1 9.2e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO86291.1 - 4.7e-06 25.7 0.2 0.0013 17.7 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 GAO86291.1 - 6.5e-06 25.2 0.0 1.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAO86291.1 - 1.9e-05 24.6 0.0 5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 GAO86291.1 - 8.2e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAO86292.1 - 2.4e-11 43.8 0.6 4.5e-11 42.9 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAO86292.1 - 3.2e-05 23.4 0.1 0.00048 19.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAO86292.1 - 0.00082 19.0 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAO86292.1 - 0.015 15.2 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain EthD PF07110.6 GAO86293.1 - 5.6e-11 43.2 0.0 7.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 EthD domain UbiA PF01040.13 GAO86294.1 - 1e-28 100.2 17.9 1.3e-28 99.8 12.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.18 GAO86295.1 - 1.7e-25 89.0 0.8 3.2e-25 88.2 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO86295.1 - 5.3e-06 26.2 0.4 1.1e-05 25.2 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Transferase PF02458.10 GAO86296.1 - 1.8e-17 62.9 0.0 2.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Methyltransf_31 PF13847.1 GAO86297.1 - 1.1e-26 93.2 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO86297.1 - 1.4e-26 92.8 0.0 2e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO86297.1 - 2.5e-17 63.0 0.0 3.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO86297.1 - 3.4e-17 62.3 0.0 4.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAO86297.1 - 6.2e-16 58.5 0.0 7.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86297.1 - 6.6e-16 58.8 0.0 1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86297.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO86297.1 - 5.3e-10 39.3 0.1 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO86297.1 - 1.4e-07 31.0 0.0 2.7e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAO86297.1 - 3.2e-07 29.8 0.0 4.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAO86297.1 - 1.1e-06 28.2 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAO86297.1 - 6.1e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 GAO86297.1 - 0.00019 20.5 0.0 0.00027 20.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 GAO86297.1 - 0.00042 19.1 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 GAO86297.1 - 0.00099 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 GAO86297.1 - 0.001 18.7 0.0 0.0047 16.5 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 GAO86297.1 - 0.0017 16.7 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 GAO86297.1 - 0.0075 15.3 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 GAO86297.1 - 0.01 16.6 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 GAO86297.1 - 0.033 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase FtsJ PF01728.14 GAO86297.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFS_1 PF07690.11 GAO86298.1 - 9.2e-31 106.8 30.0 9.2e-31 106.8 20.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 GAO86298.1 - 0.16 9.9 10.1 1 7.3 3.5 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sua5_yciO_yrdC PF01300.13 GAO86300.1 - 2.2e-13 49.8 0.0 2.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination P5CR_dimer PF14748.1 GAO86301.1 - 3.2e-29 101.0 4.5 9.3e-29 99.5 1.9 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAO86301.1 - 6.4e-10 39.3 0.0 2.5e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 GAO86301.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aldedh PF00171.17 GAO86303.1 - 1.6e-94 316.8 0.0 1.9e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.19 GAO86304.1 - 1.3e-44 152.5 0.0 1.5e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86304.1 - 8.7e-06 25.6 0.0 2.7e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO86304.1 - 0.00071 19.6 0.0 0.005 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO86304.1 - 0.00085 19.2 0.1 0.025 14.4 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO86304.1 - 0.0014 17.2 0.0 0.41 9.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 GAO86304.1 - 0.0025 16.7 0.0 0.41 9.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAO86304.1 - 0.0065 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 GAO86304.1 - 0.01 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 GAO86304.1 - 0.027 13.3 0.0 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAO86304.1 - 0.039 13.0 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 GAO86304.1 - 0.07 12.0 0.1 1 8.1 0.0 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO86304.1 - 0.073 12.8 0.3 0.51 10.1 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO86304.1 - 0.079 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAO86305.1 - 1.1e-13 50.7 1.4 2.3e-13 49.6 1.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86305.1 - 9.6e-06 25.4 17.1 1.8e-05 24.5 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 GAO86306.1 - 6.3e-67 226.0 0.0 7.1e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_32N PF00251.15 GAO86307.1 - 3e-94 315.8 8.3 3.9e-94 315.4 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAO86307.1 - 1.4e-20 73.3 0.2 4.4e-20 71.8 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal ADH_zinc_N PF00107.21 GAO86308.1 - 2.2e-24 85.4 0.3 7.9e-24 83.6 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO86308.1 - 6.4e-16 59.4 0.1 3.9e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO86308.1 - 2.1e-08 33.8 0.0 2.2e-07 30.6 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Jacalin PF01419.12 GAO86308.1 - 2.2e-06 27.6 0.1 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF4237 PF14021.1 GAO86309.1 - 4.7e-31 106.9 0.1 8.6e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) DUF3659 PF12396.3 GAO86309.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Kelch_6 PF13964.1 GAO86310.1 - 1.8e-34 116.4 9.7 2.7e-08 33.6 0.0 6.7 4 2 3 7 7 7 5 Kelch motif Kelch_1 PF01344.20 GAO86310.1 - 2.9e-25 87.5 23.8 7.9e-08 31.7 0.0 7.5 7 3 0 7 7 7 5 Kelch motif Kelch_3 PF13415.1 GAO86310.1 - 4.1e-21 74.5 11.6 0.00027 21.0 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 GAO86310.1 - 3.1e-14 52.0 1.6 0.088 12.6 0.0 6.8 5 2 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 GAO86310.1 - 1.6e-11 43.9 5.1 0.015 15.2 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 GAO86310.1 - 3.9e-11 42.5 22.2 0.0056 16.4 0.0 7.2 6 1 1 7 7 7 3 Galactose oxidase, central domain DUF1668 PF07893.8 GAO86310.1 - 0.00012 21.3 0.3 0.0048 16.0 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) SNF2_N PF00176.18 GAO86311.1 - 4.3e-22 78.2 0.0 9.5e-22 77.1 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAO86311.1 - 0.089 12.6 0.0 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ank_2 PF12796.2 GAO86312.1 - 4.9e-09 36.4 0.0 3.8e-07 30.3 0.0 3.3 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO86312.1 - 2.2e-07 31.2 2.0 0.17 12.4 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86312.1 - 1.6e-06 27.7 0.2 0.3 11.4 0.1 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 GAO86312.1 - 0.00065 19.8 2.0 0.73 10.1 0.1 4.4 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.25 GAO86312.1 - 0.0011 18.7 0.3 0.091 12.6 0.2 3.6 3 0 0 3 3 3 1 Ankyrin repeat Pentapeptide_3 PF13576.1 GAO86312.1 - 0.1 12.5 1.1 0.31 10.9 0.8 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Glyco_hydro_71 PF03659.9 GAO86313.1 - 9.6e-158 524.6 5.3 1.7e-157 523.8 2.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Peptidase_S8 PF00082.17 GAO86313.1 - 2.7e-13 49.7 0.0 5.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Nodulin_late PF07127.6 GAO86313.1 - 0.092 12.8 2.1 0.31 11.1 1.4 2.0 1 0 0 1 1 1 0 Late nodulin protein CI-B14_5a PF07347.7 GAO86313.1 - 0.17 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ras PF00071.17 GAO86314.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Ras family ATG_C PF09333.6 GAO86317.1 - 0.12 12.5 1.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 ATG C terminal domain Ank_2 PF12796.2 GAO86318.1 - 9.3e-38 128.4 0.0 1.2e-12 47.9 0.0 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86318.1 - 6.8e-21 72.9 1.3 2.5e-06 27.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 GAO86318.1 - 3.6e-19 66.9 0.3 4.5e-06 26.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAO86318.1 - 7.7e-16 58.1 2.2 8e-07 29.4 0.1 4.2 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86318.1 - 1.2e-15 57.2 0.7 0.0034 17.5 0.1 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) LysM PF01476.15 GAO86319.1 - 3.8e-27 93.9 1.5 1.4e-05 24.9 0.0 5.3 5 0 0 5 5 5 5 LysM domain Hce2 PF14856.1 GAO86319.1 - 6.3 6.7 9.4 1.1 9.2 0.2 3.4 3 1 0 3 3 3 0 Pathogen effector; putative necrosis-inducing factor FAD_binding_4 PF01565.18 GAO86320.1 - 1.2e-19 70.1 0.3 2.5e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO86320.1 - 6.5e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAO86320.1 - 0.083 12.0 0.7 0.37 9.8 0.2 2.0 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RVT_1 PF00078.22 GAO86321.1 - 6.2e-11 42.0 0.0 1.1e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ChaB PF06150.7 GAO86321.1 - 0.1 12.4 1.2 0.33 10.7 0.9 1.8 1 0 0 1 1 1 0 ChaB p450 PF00067.17 GAO86322.1 - 3.7e-30 104.8 0.0 4.5e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF21 PF01595.15 GAO86322.1 - 0.14 11.4 0.7 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 Oxidored_FMN PF00724.15 GAO86323.1 - 0.0023 16.9 0.0 0.027 13.4 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 GAO86324.1 - 1.2e-41 142.5 88.4 1.4e-29 102.8 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86324.1 - 2.1e-08 33.1 51.7 0.00014 20.5 11.3 3.2 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAO86324.1 - 3.7e-06 26.6 5.5 0.00067 19.4 1.9 3.5 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 GAO86324.1 - 0.00046 18.7 21.2 0.00046 18.7 14.7 3.1 1 1 3 4 4 4 3 MFS/sugar transport protein Zn_clus PF00172.13 GAO86325.1 - 1.9e-07 30.8 8.9 3.8e-07 29.8 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAO86325.1 - 0.87 9.8 9.7 1.8 8.7 6.7 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Methyltransf_2 PF00891.13 GAO86326.1 - 4.2e-07 29.4 0.0 7.6e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Fungal_trans PF04082.13 GAO86327.1 - 5.4e-11 41.8 0.3 9.1e-11 41.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 GAO86328.1 - 2.9e-90 303.0 1.8 3.4e-90 302.8 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AMP-binding PF00501.23 GAO86329.1 - 3e-78 263.0 0.0 4.5e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAO86329.1 - 1.6e-18 66.6 0.0 3.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 GAO86329.1 - 0.00012 22.2 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO86329.1 - 0.0016 19.3 0.1 0.034 15.0 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 GAO86330.1 - 1.6e-39 135.2 0.0 5e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO86330.1 - 3e-26 92.4 25.0 7.9e-25 87.8 8.4 2.9 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAO86330.1 - 1.2e-11 45.1 0.0 0.015 15.2 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAO86330.1 - 6.1e-10 38.7 0.9 0.021 14.0 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAO86330.1 - 4.1e-07 29.4 0.4 0.034 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO86330.1 - 1.6e-06 28.9 0.0 0.031 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO86330.1 - 5.8e-06 26.4 0.0 0.16 12.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAO86330.1 - 7.2e-06 25.9 0.0 0.023 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO86330.1 - 8.5e-06 25.2 0.0 0.043 13.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 GAO86330.1 - 9e-06 25.3 0.3 0.025 14.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 GAO86330.1 - 1.7e-05 23.9 0.0 0.0057 15.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 GAO86330.1 - 4.3e-05 23.3 2.6 0.1 12.5 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 GAO86330.1 - 5.2e-05 23.1 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 GAO86330.1 - 0.00012 22.5 0.0 0.04 14.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 GAO86330.1 - 0.00016 21.6 0.1 0.078 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain DUF87 PF01935.12 GAO86330.1 - 0.00017 21.4 0.5 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 GAO86330.1 - 0.00027 21.2 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAO86330.1 - 0.00049 19.6 0.8 0.22 10.9 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 GAO86330.1 - 0.00053 19.7 0.2 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 GAO86330.1 - 0.00073 19.9 1.3 0.91 9.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO86330.1 - 0.0016 17.6 0.0 0.68 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 GAO86330.1 - 0.0018 17.8 0.2 0.057 12.9 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 GAO86330.1 - 0.002 18.0 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.10 GAO86330.1 - 0.0027 16.4 0.1 0.59 8.7 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein RNA_helicase PF00910.17 GAO86330.1 - 0.015 15.4 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 GAO86330.1 - 0.037 14.2 0.6 1.3 9.2 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAO86330.1 - 0.061 12.9 0.1 33 3.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 GAO86330.1 - 0.076 12.6 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAO86330.1 - 0.079 12.6 0.1 20 4.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.24 GAO86330.1 - 0.16 11.4 0.0 3.9 6.9 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_19 PF13245.1 GAO86330.1 - 0.39 10.5 4.2 1.7 8.4 0.0 3.9 5 0 0 5 5 3 0 Part of AAA domain Apo-VLDL-II PF05418.6 GAO86331.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) NAGLU PF05089.7 GAO86332.1 - 2e-127 424.5 8.7 2.7e-127 424.1 6.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAO86332.1 - 6.3e-64 215.9 2.4 6.3e-64 215.9 1.6 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAO86332.1 - 2.1e-17 62.5 0.1 9.2e-17 60.5 0.0 2.2 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PilJ PF13675.1 GAO86332.1 - 0.016 15.5 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AMP-binding PF00501.23 GAO86333.1 - 4.1e-165 549.2 0.3 1.6e-82 277.1 0.4 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO86333.1 - 2e-73 246.8 0.0 3.9e-35 121.1 0.0 3.6 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.20 GAO86333.1 - 8.8e-19 67.5 0.0 3.5e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO86333.1 - 1.9e-14 54.3 0.4 5.3e-07 30.4 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.18 GAO86334.1 - 8e-16 57.7 3.7 6.2e-09 35.4 2.1 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 GAO86334.1 - 6e-07 29.2 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Trp_DMAT PF11991.3 GAO86335.1 - 4.2e-96 322.2 0.0 4.8e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Phage_portal PF04860.7 GAO86335.1 - 0.2 10.2 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein Trp_DMAT PF11991.3 GAO86336.1 - 5.1e-88 295.7 0.0 8.2e-88 295.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 GAO86336.1 - 9.9e-56 189.1 0.0 1.4e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO86337.1 - 4.8e-58 196.7 0.0 6.7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3243 PF11588.3 GAO86337.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) DIOX_N PF14226.1 GAO86338.1 - 1.5e-17 64.2 0.0 3.3e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO86338.1 - 6.9e-13 48.7 0.0 3.5e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_S15 PF02129.13 GAO86339.1 - 3.4e-38 131.6 0.2 3.1e-36 125.2 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAO86339.1 - 3.1e-22 79.5 0.0 4.6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAO86339.1 - 7.5e-08 32.5 0.9 1.4e-07 31.6 0.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4137 PF13593.1 GAO86340.1 - 2.6e-62 210.7 20.2 3.6e-62 210.2 14.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Condensation PF00668.15 GAO86340.1 - 5.7e-23 81.2 3.7 2e-11 43.2 0.4 2.6 3 0 0 3 3 3 2 Condensation domain SBF PF01758.11 GAO86340.1 - 5.1e-08 32.5 7.8 5.1e-08 32.5 5.4 1.8 1 1 0 1 1 1 1 Sodium Bile acid symporter family TauD PF02668.11 GAO86341.1 - 6.2e-15 55.5 0.0 8.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PAD_porph PF04371.10 GAO86343.1 - 3.6e-72 243.1 0.0 5e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase MFS_1 PF07690.11 GAO86344.1 - 2.5e-51 174.4 28.1 3.8e-39 134.4 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 GAO86344.1 - 1.5e-05 23.3 7.9 0.00027 19.2 3.3 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.19 GAO86344.1 - 0.00056 18.6 17.2 0.0063 15.1 10.1 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter 5HT_transporter PF03491.8 GAO86344.1 - 0.019 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus MFS_1_like PF12832.2 GAO86344.1 - 0.033 13.9 3.7 3 7.6 0.0 3.4 4 1 0 4 4 4 0 MFS_1 like family ATG22 PF11700.3 GAO86344.1 - 0.11 10.9 14.2 0.18 10.2 2.1 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF4131 PF13567.1 GAO86344.1 - 8.5 5.7 12.7 0.33 10.3 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Orn_Arg_deC_N PF02784.11 GAO86345.1 - 2e-62 210.6 0.0 2.7e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAO86345.1 - 1.7e-26 92.2 0.1 2.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CP_ATPgrasp_2 PF14403.1 GAO86346.1 - 0.021 13.4 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_2 PF14403.1 GAO86347.1 - 2.3e-10 39.7 0.0 1.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 ATPgrasp_ST PF14397.1 GAO86347.1 - 0.0078 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.1 GAO86347.1 - 0.032 13.9 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TTL PF03133.10 GAO86347.1 - 0.035 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family FAD_binding_3 PF01494.14 GAO86348.1 - 5.5e-75 252.6 0.0 1.9e-49 168.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 GAO86348.1 - 6.4e-31 107.2 0.0 1.3e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAO86348.1 - 7.3e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAO86348.1 - 1e-05 24.2 0.1 1.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO86348.1 - 3.4e-05 22.8 0.1 5.1e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO86348.1 - 8.7e-05 21.7 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO86348.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 GAO86348.1 - 0.00021 20.3 0.1 0.0015 17.5 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase SE PF08491.5 GAO86348.1 - 0.00026 19.9 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 GAO86348.1 - 0.00083 19.2 0.0 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86348.1 - 0.0016 18.3 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO86348.1 - 0.0019 18.5 0.1 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO86348.1 - 0.0057 16.7 1.5 0.031 14.3 1.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO86348.1 - 0.035 12.7 0.1 0.053 12.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAO86348.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Sdh_cyt PF01127.17 GAO86350.1 - 3e-17 62.5 6.0 4.1e-17 62.1 4.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CDC50 PF03381.10 GAO86350.1 - 0.021 14.0 0.9 0.028 13.5 0.6 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Methyltransf_2 PF00891.13 GAO86351.1 - 2.1e-06 27.1 0.0 4.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAO86351.1 - 0.017 14.9 0.1 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Fungal_trans PF04082.13 GAO86352.1 - 1e-17 63.9 0.1 1.7e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86352.1 - 1.1e-07 31.6 6.3 2e-07 30.7 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO86353.1 - 7.2e-10 38.1 0.9 1.3e-09 37.3 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86353.1 - 9.5e-08 31.8 11.6 1.9e-07 30.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COMP PF11598.3 GAO86353.1 - 0.005 16.8 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein DUF1319 PF07028.6 GAO86353.1 - 0.045 13.9 0.6 0.47 10.6 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) HWE_HK PF07536.9 GAO86353.1 - 0.086 13.2 1.0 0.22 11.9 0.6 1.7 1 1 0 1 1 1 0 HWE histidine kinase IncA PF04156.9 GAO86353.1 - 1.6 8.3 6.3 37 3.8 4.4 2.3 1 1 0 1 1 1 0 IncA protein MFS_1 PF07690.11 GAO86354.1 - 2.7e-35 121.7 68.8 2.9e-28 98.6 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO86354.1 - 0.012 15.3 19.5 0.017 14.9 2.2 3.9 4 0 0 4 4 4 0 MFS_1 like family DUF1320 PF07030.7 GAO86356.1 - 0.033 13.9 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Coat_F PF07875.7 GAO86356.1 - 0.05 13.7 0.8 0.097 12.8 0.5 1.4 1 0 0 1 1 1 0 Coat F domain Amino_oxidase PF01593.19 GAO86357.1 - 1.1e-27 97.1 0.7 2.6e-27 96.0 0.5 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO86357.1 - 9.6e-07 28.7 0.0 2.4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO86357.1 - 3.3e-05 24.0 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO86357.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain XH PF03469.9 GAO86359.1 - 0.0022 17.6 8.5 0.0095 15.5 0.2 3.3 2 1 2 4 4 4 2 XH domain DUF883 PF05957.8 GAO86359.1 - 0.043 14.2 10.4 5.9 7.3 0.0 5.7 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF1870 PF08965.5 GAO86359.1 - 0.047 13.3 0.2 5.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) NPV_P10 PF05531.7 GAO86359.1 - 0.081 13.1 0.7 8.6 6.6 0.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4145 PF13643.1 GAO86359.1 - 0.37 10.6 0.0 0.37 10.6 0.0 2.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4145) SRP54_N PF02881.14 GAO86359.1 - 1.3 9.1 5.8 3 7.9 0.0 3.6 3 1 1 4 4 4 0 SRP54-type protein, helical bundle domain YtxH PF12732.2 GAO86359.1 - 2.4 8.5 27.9 1.6 9.1 0.5 6.4 4 1 1 5 5 5 0 YtxH-like protein DUF964 PF06133.6 GAO86359.1 - 5.6 7.0 13.1 1.5 8.8 0.4 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF964) CRAL_TRIO PF00650.15 GAO86360.1 - 6.8e-43 145.9 0.0 1.2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAO86360.1 - 4e-08 33.3 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO86360.1 - 9.8e-05 22.4 0.1 0.00032 20.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF3759 PF12585.3 GAO86361.1 - 6e-36 122.2 4.5 9.4e-36 121.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Glyco_hydro_45 PF02015.11 GAO86362.1 - 1.7e-22 80.5 21.6 1.7e-22 80.5 15.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 GAO86362.1 - 7.8e-15 54.2 8.0 7.8e-15 54.2 5.5 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.13 GAO86362.1 - 1.7e-08 34.3 0.8 1.7e-08 34.3 0.5 2.5 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Tannase PF07519.6 GAO86363.1 - 2.1e-108 363.0 2.3 2.8e-108 362.6 1.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAO86363.1 - 0.02 14.6 0.0 0.88 9.3 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 GAO86364.1 - 4.9e-119 397.8 19.6 7.3e-119 397.2 13.6 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86364.1 - 7.5e-28 97.2 32.0 2.7e-27 95.4 18.8 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF455 PF04305.9 GAO86365.1 - 5.5e-107 356.7 0.1 6.6e-107 356.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 GAO86365.1 - 1.4e-05 24.5 0.1 3.1e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAO86365.1 - 0.0012 18.5 0.0 0.01 15.5 0.0 2.5 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Ank_2 PF12796.2 GAO86367.1 - 2.2e-77 255.4 1.2 6.1e-22 77.7 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86367.1 - 2.7e-77 250.9 3.6 2.8e-09 36.3 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 GAO86367.1 - 6.5e-55 177.6 0.0 3.3e-05 23.7 0.0 10.9 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 GAO86367.1 - 7e-46 153.8 3.3 2.5e-11 43.7 0.0 9.1 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86367.1 - 1.4e-43 145.9 5.7 4.9e-11 42.5 0.0 7.9 2 2 7 9 9 9 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAO86367.1 - 3.5e-11 42.5 0.1 8.2e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO86367.1 - 2e-05 24.3 0.0 6.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAO86367.1 - 0.011 15.9 0.1 0.058 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Nitro_FeMo-Co PF02579.12 GAO86367.1 - 0.017 15.1 0.2 26 4.9 0.0 3.7 2 2 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor KAP_NTPase PF07693.9 GAO86367.1 - 0.087 11.7 0.1 7.9 5.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 GAO86367.1 - 0.099 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 GAO86367.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF4541 PF15074.1 GAO86367.1 - 0.13 12.7 0.0 37 4.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) AAA PF00004.24 GAO86368.1 - 5.7e-18 65.3 0.0 1.4e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO86368.1 - 0.0029 17.7 0.1 0.11 12.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 GAO86368.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAO86368.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAO86368.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAO86368.1 - 0.02 15.6 0.0 0.099 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAO86368.1 - 0.045 13.7 0.2 0.22 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 GAO86368.1 - 0.057 12.5 0.3 1.7 7.7 0.1 2.3 1 1 1 2 2 2 0 KaiC ACT_3 PF10000.4 GAO86369.1 - 2.4e-21 75.2 0.1 5.8e-21 74.0 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 GAO86369.1 - 1.4e-11 43.6 0.1 2.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain Gal-bind_lectin PF00337.17 GAO86370.1 - 0.00089 18.6 0.4 0.0018 17.6 0.2 1.4 1 1 0 1 1 1 1 Galactoside-binding lectin TPR_11 PF13414.1 GAO86371.1 - 2e-08 33.7 1.2 1.9e-05 24.1 0.0 3.9 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 GAO86371.1 - 2.1e-08 33.4 2.6 1.2e-05 24.7 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86371.1 - 7.3e-07 29.0 2.7 0.39 10.6 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAO86371.1 - 1.6e-06 28.2 0.0 9.2e-06 25.7 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.23 GAO86371.1 - 1.1e-05 24.8 0.0 0.00014 21.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO86371.1 - 4.6e-05 22.8 0.0 0.0048 16.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO86371.1 - 8.4e-05 22.8 6.2 0.035 14.7 0.0 5.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAO86371.1 - 0.00012 21.9 0.2 0.28 11.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.7 GAO86371.1 - 0.00024 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.1 GAO86371.1 - 0.0026 18.0 8.6 0.21 11.9 0.0 5.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO86371.1 - 0.014 15.7 7.8 21 5.8 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAO86371.1 - 0.028 14.5 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAO86371.1 - 0.032 13.3 0.6 0.54 9.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin TPR_7 PF13176.1 GAO86371.1 - 0.14 12.0 2.8 3.9 7.5 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO86371.1 - 0.49 10.9 4.2 3.1 8.4 0.7 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86371.1 - 1.2 9.9 9.9 2.1 9.1 0.1 3.8 3 1 0 3 3 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAO86373.1 - 5.8e-19 68.8 0.0 8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86373.1 - 4.9e-15 55.7 0.0 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO86373.1 - 1.5e-06 28.0 0.0 3.4e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAO86373.1 - 0.022 13.2 0.0 0.048 12.1 0.0 1.5 2 0 0 2 2 2 0 Ndr family p450 PF00067.17 GAO86374.1 - 4.1e-56 190.4 0.0 6.3e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.15 GAO86376.1 - 6.5e-41 140.1 0.1 7.4e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.12 GAO86376.1 - 0.06 13.1 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Hira PF07569.6 GAO86376.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 TUP1-like enhancer of split FMN_red PF03358.10 GAO86377.1 - 2.8e-27 95.1 0.0 6.1e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Fungal_trans_2 PF11951.3 GAO86377.1 - 9e-08 31.1 0.1 1.5e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavodoxin_2 PF02525.12 GAO86377.1 - 1.2e-05 24.8 0.0 3.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin-like fold DUF2605 PF10792.4 GAO86377.1 - 0.074 12.7 0.4 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Cation_efflux PF01545.16 GAO86378.1 - 6.7e-39 133.6 0.6 1.4e-38 132.6 0.4 1.5 1 0 0 1 1 1 1 Cation efflux family FAD_binding_4 PF01565.18 GAO86378.1 - 1.5e-17 63.3 0.2 3.8e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 GAO86378.1 - 1.9e-17 63.0 1.3 3e-17 62.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BBE PF08031.7 GAO86378.1 - 2.5e-09 36.8 0.2 6.6e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like BPD_transp_2 PF02653.11 GAO86378.1 - 0.0034 16.4 0.2 0.006 15.5 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Beta_elim_lyase PF01212.16 GAO86379.1 - 2.6e-38 131.8 0.1 3.2e-38 131.5 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAO86379.1 - 0.00027 19.9 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF373 PF04123.8 GAO86380.1 - 0.048 12.6 1.3 3.8 6.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1218 PF06749.7 GAO86380.1 - 0.23 11.9 2.2 0.41 11.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Phageshock_PspG PF09583.5 GAO86380.1 - 1.4 8.9 12.8 1.1 9.3 0.7 3.0 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) DUF1206 PF06724.6 GAO86380.1 - 5.4 6.8 8.0 0.48 10.2 0.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) MAPEG PF01124.13 GAO86380.1 - 6.8 6.3 10.2 6.8 6.3 0.1 3.1 2 2 1 3 3 3 0 MAPEG family CoA_transf_3 PF02515.12 GAO86382.1 - 1.2e-56 190.9 0.0 1.7e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 GAO86383.1 - 1.2e-31 109.8 0.7 4.5e-31 107.9 0.6 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 GAO86383.1 - 5.7e-22 77.8 0.2 4e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Acyl-CoA_dh_N PF02771.11 GAO86383.1 - 4.2e-18 65.9 0.3 9.2e-18 64.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAO86383.1 - 2.3e-15 57.0 0.4 2.3e-15 57.0 0.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAO86383.1 - 2.4e-11 42.9 0.2 5.4e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DeoC PF01791.4 GAO86384.1 - 2.1e-39 135.1 2.1 2.4e-39 135.0 1.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase QRPTase_C PF01729.14 GAO86384.1 - 0.077 12.5 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain GST_N_2 PF13409.1 GAO86386.1 - 5.4e-14 51.9 0.1 2.5e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO86386.1 - 5.2e-11 42.2 0.0 1.6e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO86386.1 - 0.00092 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO86386.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO86386.1 - 0.0094 16.1 0.1 4.8 7.4 0.0 3.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain Chitin_bind_3 PF03067.10 GAO86387.1 - 5.4e-11 43.1 0.1 1.8e-08 34.8 0.0 2.2 1 1 0 2 2 2 2 Chitin binding domain F-box-like PF12937.2 GAO86388.1 - 8.9e-12 44.5 1.3 8.9e-12 44.5 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAO86388.1 - 0.0031 17.1 0.4 0.076 12.7 0.2 2.9 2 1 0 2 2 2 1 F-box domain BNR_2 PF13088.1 GAO86389.1 - 1.4e-11 44.1 0.5 8.5e-09 35.0 0.1 3.2 1 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.15 GAO86389.1 - 3e-06 26.2 16.3 0.36 10.8 0.4 5.1 4 0 0 4 4 4 4 BNR/Asp-box repeat Oxidored_FMN PF00724.15 GAO86390.1 - 7.5e-70 235.5 0.0 9.9e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 GAO86390.1 - 0.0042 15.9 0.2 0.052 12.3 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Glyco_hydro_28 PF00295.12 GAO86391.1 - 6.1e-33 114.1 9.8 3.9e-25 88.4 2.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase PF03211.8 GAO86392.1 - 6.4e-62 208.7 3.6 7.6e-62 208.5 2.5 1.0 1 0 0 1 1 1 1 Pectate lyase Zn_clus PF00172.13 GAO86393.1 - 7.7e-08 32.1 4.8 1.4e-07 31.3 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO86393.1 - 9e-06 24.5 0.1 1.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAO86394.1 - 3.2e-59 200.1 7.5 3.2e-59 200.1 5.2 1.5 2 0 0 2 2 2 1 RTA1 like protein Glyco_transf_28 PF03033.15 GAO86395.1 - 4.8e-22 78.2 0.0 1.6e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAO86395.1 - 0.00027 19.6 0.0 0.00048 18.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PaO PF08417.7 GAO86395.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase RTA1 PF04479.8 GAO86396.1 - 9.3e-60 201.9 7.1 1.3e-59 201.4 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_10 PF00331.15 GAO86397.1 - 5e-65 219.6 0.0 5.8e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.19 GAO86398.1 - 3.2e-79 266.6 23.8 3.6e-79 266.4 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86398.1 - 3.1e-19 68.9 27.2 3.1e-19 68.9 18.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO86398.1 - 7.9e-05 21.2 30.4 8.2e-05 21.1 2.4 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein Alpha-amylase PF00128.19 GAO86399.1 - 1.7e-100 336.4 0.0 4.7e-100 335.0 0.0 1.7 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Zn_clus PF00172.13 GAO86399.1 - 1.9e-07 30.8 12.1 3.4e-07 30.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO86399.1 - 0.00024 20.0 5.3 0.0013 17.6 3.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain hDGE_amylase PF14701.1 GAO86399.1 - 0.009 14.9 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF3425 PF11905.3 GAO86400.1 - 7.8e-39 132.6 1.0 1.5e-38 131.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Plasmod_MYXSPDY PF07981.6 GAO86400.1 - 0.14 11.8 1.4 0.29 10.8 1.0 1.5 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY bZIP_1 PF00170.16 GAO86400.1 - 0.15 12.0 9.8 0.26 11.2 6.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Ilar_coat PF01787.11 GAO86400.1 - 0.24 10.9 5.2 0.36 10.3 3.6 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein PHO4 PF01384.15 GAO86401.1 - 3.1e-99 331.7 15.0 3.7e-99 331.4 10.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Syndecan PF01034.15 GAO86401.1 - 0.096 12.3 2.8 0.16 11.6 0.1 2.9 3 0 0 3 3 3 0 Syndecan domain COesterase PF00135.23 GAO86405.1 - 3.7e-93 313.0 0.1 3.9e-87 293.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO86405.1 - 1.9e-09 37.4 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO86405.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAO86405.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Fungal_trans PF04082.13 GAO86406.1 - 4.7e-12 45.3 2.6 6.8e-12 44.8 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 GAO86406.1 - 9.5e-08 31.0 1.4 9.5e-08 31.0 1.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86406.1 - 2.3e-07 30.5 7.0 4.2e-07 29.7 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL_2 PF13472.1 GAO86407.1 - 4.1e-15 56.3 0.2 5e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO86407.1 - 8.4e-07 29.0 0.1 9.8e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.9 GAO86408.1 - 2.1e-13 50.0 7.3 8.9e-12 44.6 2.4 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 GAO86409.1 - 3.2e-21 75.3 0.4 4.4e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 GAO86410.1 - 5.8e-18 65.2 0.0 3.2e-16 59.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO86410.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO86410.1 - 3e-07 30.5 0.2 3.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO86410.1 - 6.5e-07 28.7 0.0 0.066 12.4 0.0 3.0 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAO86410.1 - 3.5e-05 23.3 0.0 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 GAO86410.1 - 0.00066 18.2 0.0 0.0015 17.0 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) COesterase PF00135.23 GAO86410.1 - 0.0015 17.3 0.1 0.011 14.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 GAO86410.1 - 0.024 13.9 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.15 GAO86410.1 - 0.054 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FAD_binding_3 PF01494.14 GAO86411.1 - 4.5e-53 180.5 0.0 5.8e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO86411.1 - 1.3e-09 37.4 3.2 8e-07 28.2 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO86411.1 - 7.1e-08 31.7 2.9 7.6e-05 21.7 0.3 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAO86411.1 - 3.3e-07 30.4 0.1 5e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86411.1 - 3.5e-06 26.9 0.2 9.4e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO86411.1 - 3.7e-06 25.6 1.0 4.5e-05 22.1 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAO86411.1 - 7.3e-05 21.9 0.1 0.00016 20.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAO86411.1 - 0.00032 20.8 0.1 0.00091 19.3 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO86411.1 - 0.00044 20.6 0.3 0.0055 17.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO86411.1 - 0.00054 19.1 1.4 0.005 15.9 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO86411.1 - 0.00084 18.3 0.3 0.0019 17.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO86411.1 - 0.0067 16.2 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAO86411.1 - 0.0068 16.6 0.0 0.02 15.1 0.0 1.8 2 0 0 2 2 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAO86411.1 - 0.014 14.7 0.1 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 GAO86411.1 - 0.017 13.9 0.2 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAO86411.1 - 0.018 14.6 0.1 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAO86411.1 - 0.022 14.1 0.1 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 GAO86411.1 - 0.052 13.3 0.1 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 GAO86411.1 - 0.084 11.4 0.4 0.24 10.0 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.14 GAO86411.1 - 0.11 11.6 0.0 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAO86411.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Lysine_decarbox PF03641.9 GAO86412.1 - 1.4e-28 99.3 0.0 2.5e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase DIOX_N PF14226.1 GAO86414.1 - 4.3e-18 65.9 0.0 7.9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO86414.1 - 8.9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Orthopox_A5L PF06193.6 GAO86414.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Zn_clus PF00172.13 GAO86415.1 - 1.9e-05 24.4 11.8 1.9e-05 24.4 8.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 GAO86416.1 - 9.3e-10 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86416.1 - 1.2e-07 31.4 0.0 5.8e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86416.1 - 3.9e-06 27.4 0.3 3.9e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO86416.1 - 1.1e-05 25.8 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86416.1 - 0.00036 20.9 0.0 0.00081 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO86416.1 - 0.051 13.6 0.3 1.8 8.5 0.1 2.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.11 GAO86416.1 - 0.083 11.2 0.2 0.17 10.1 0.1 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AMP-binding PF00501.23 GAO86417.1 - 4.5e-65 219.6 0.0 5.7e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO86417.1 - 1.1e-05 26.3 0.0 2.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GnsAB PF08178.6 GAO86417.1 - 0.023 14.3 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 GnsA/GnsB family COG5 PF10392.4 GAO86417.1 - 0.057 13.3 0.3 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DAHP_synth_2 PF01474.11 GAO86418.1 - 2.1e-144 481.1 0.0 3.5e-87 292.5 0.0 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family SGL PF08450.7 GAO86419.1 - 2.4e-15 56.5 0.2 2.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 GAO86419.1 - 0.00022 21.1 0.0 0.00089 19.2 0.0 2.1 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 GAO86419.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Arylesterase Glyco_hydro_88 PF07470.8 GAO86420.1 - 1.4e-26 93.3 0.0 2.3e-25 89.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 GAO86421.1 - 1.3e-39 135.9 93.5 1.3e-34 119.4 43.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WBP-1 PF11669.3 GAO86421.1 - 0.24 11.5 3.1 0.31 11.1 0.4 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 Epimerase PF01370.16 GAO86422.1 - 1.1e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO86422.1 - 5.6e-09 36.2 0.1 1.2e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO86422.1 - 3.2e-07 29.5 0.0 2.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAO86422.1 - 9.5e-07 27.7 0.0 1.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO86422.1 - 0.015 15.1 0.2 0.089 12.7 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 GAO86422.1 - 0.025 13.8 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DNA_pol_E_B PF04042.11 GAO86422.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B GMC_oxred_N PF00732.14 GAO86423.1 - 8.3e-55 186.0 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO86423.1 - 7.7e-31 107.3 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO86423.1 - 2.1e-08 33.4 0.2 0.0028 16.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO86423.1 - 1.6e-06 27.2 0.2 0.00021 20.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO86423.1 - 9.8e-06 25.5 0.1 4.4e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO86423.1 - 0.0024 17.0 0.1 0.1 11.6 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 GAO86423.1 - 0.0033 17.4 1.9 2.5 8.1 0.9 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86423.1 - 0.019 14.9 2.7 0.025 14.5 0.9 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAO86423.1 - 0.02 13.7 0.9 0.46 9.2 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAO86423.1 - 0.025 14.9 1.0 0.24 11.8 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO86423.1 - 0.063 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAO86423.1 - 0.07 12.1 0.2 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 GAO86423.1 - 0.17 10.9 1.1 1.2 8.0 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO86423.1 - 0.19 10.1 0.4 0.27 9.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein BTB PF00651.26 GAO86424.1 - 2e-05 24.5 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain adh_short PF00106.20 GAO86425.1 - 8.3e-25 87.6 0.1 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAO86425.1 - 1.6e-10 40.8 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAO86425.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO86425.1 - 2.8e-08 33.8 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO86425.1 - 9.6e-06 25.7 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAO86425.1 - 0.00058 18.8 0.1 0.00096 18.1 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAO86425.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 GAO86425.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) DASH_Duo1 PF08651.5 GAO86425.1 - 0.026 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 NmrA PF05368.8 GAO86425.1 - 0.03 13.5 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 GAO86425.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NUDIX PF00293.23 GAO86426.1 - 5.2e-06 26.1 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_12 PF01670.11 GAO86428.1 - 1.1e-55 187.6 1.5 1.1e-55 187.6 1.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_3 PF00933.16 GAO86429.1 - 1.5e-89 299.8 0.0 2.2e-89 299.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO86429.1 - 1.1e-59 201.6 1.0 3e-59 200.3 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO86429.1 - 2.8e-26 91.2 0.1 6.2e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain BTB PF00651.26 GAO86430.1 - 3.1e-10 40.0 0.0 8.6e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain F-box-like PF12937.2 GAO86430.1 - 1.4e-07 31.1 0.1 3.2e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 GAO86431.1 - 2.2e-40 138.4 66.4 1.1e-39 136.1 31.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86431.1 - 1.4e-10 40.3 28.8 1.6e-08 33.6 10.4 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAO86431.1 - 3.7e-10 38.6 15.9 3.7e-10 38.6 11.0 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 GAO86431.1 - 0.0031 16.9 1.4 0.0066 15.8 1.0 1.5 1 0 0 1 1 1 1 WTF protein AMP-binding PF00501.23 GAO86432.1 - 5.1e-159 529.1 0.0 5.9e-82 275.2 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO86432.1 - 1.2e-66 224.6 0.0 5.9e-31 107.4 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 GAO86432.1 - 8.4e-28 96.4 0.7 5.1e-09 36.2 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO86432.1 - 7.7e-18 65.2 1.8 1.8e-08 35.2 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAO86432.1 - 0.34 9.3 0.0 2.8 6.2 0.0 2.0 2 0 0 2 2 2 0 Transferase family DUF2232 PF09991.4 GAO86432.1 - 1.8 7.4 0.0 3.2 6.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Epimerase PF01370.16 GAO86433.1 - 2.3e-14 53.4 0.0 5e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO86433.1 - 6.7e-08 32.7 0.0 6.3e-07 29.5 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO86433.1 - 0.00012 20.9 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAO86433.1 - 0.00023 20.4 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAO86433.1 - 0.015 15.2 0.2 0.062 13.2 0.1 2.1 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO86433.1 - 0.038 12.9 0.0 6.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF3511 PF12023.3 GAO86433.1 - 0.071 12.4 0.0 0.89 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) MFS_1 PF07690.11 GAO86435.1 - 1.3e-29 102.9 26.8 2.5e-29 102.0 17.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 GAO86436.1 - 3.3e-63 213.4 2.6 4.4e-63 213.0 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ACOX PF01756.14 GAO86437.1 - 4.7e-40 136.9 0.0 1.2e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAO86437.1 - 2.4e-25 89.2 2.7 4.5e-25 88.3 1.9 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 GAO86437.1 - 5.6e-12 44.9 0.8 1.4e-11 43.6 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAO86437.1 - 5.5e-05 23.3 1.5 0.012 15.7 1.0 2.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_31 PF13847.1 GAO86438.1 - 4.7e-27 94.4 0.0 5.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO86438.1 - 6.1e-26 90.7 0.0 9.8e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86438.1 - 3.2e-18 66.0 0.0 4.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO86438.1 - 1.5e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86438.1 - 2.2e-17 63.6 0.0 3.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO86438.1 - 5.5e-17 61.6 0.0 7.4e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAO86438.1 - 3.9e-15 55.9 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO86438.1 - 7.5e-12 45.3 0.4 1.5e-11 44.3 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO86438.1 - 5.7e-10 38.8 0.0 8.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAO86438.1 - 6.8e-09 35.3 0.0 9.5e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAO86438.1 - 1.6e-06 27.2 0.0 2.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 GAO86438.1 - 2.2e-06 27.3 0.0 3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 GAO86438.1 - 9e-05 21.7 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 GAO86438.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.13 GAO86438.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 GAO86438.1 - 0.00031 19.5 0.0 0.00038 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.7 GAO86438.1 - 0.0017 17.2 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 GAO86438.1 - 0.0019 17.8 0.0 0.0091 15.6 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.15 GAO86438.1 - 0.0021 17.1 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 GAO86438.1 - 0.0061 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 GAO86438.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB CheR PF01739.13 GAO86438.1 - 0.044 13.0 0.0 0.16 11.2 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 GAO86438.1 - 0.06 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 GAO86438.1 - 0.065 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase HET PF06985.6 GAO86439.1 - 1.2e-06 28.7 0.0 2.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2390 PF09523.5 GAO86441.1 - 0.011 15.8 0.5 0.024 14.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) BOP1NT PF08145.7 GAO86441.1 - 0.041 13.6 0.2 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain Zn_clus PF00172.13 GAO86443.1 - 1.9e-07 30.8 9.4 2.9e-07 30.2 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos_2 PF14529.1 GAO86444.1 - 9.1e-07 28.5 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase adh_short PF00106.20 GAO86445.1 - 7.4e-15 55.2 0.8 9.9e-15 54.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO86445.1 - 2.7e-07 30.4 0.6 3.9e-07 29.9 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO86445.1 - 7e-05 22.7 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAO86445.1 - 0.00045 19.9 0.8 0.0014 18.3 0.1 2.0 2 1 1 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO86445.1 - 0.001 18.5 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Histidinol_dh PF00815.15 GAO86446.1 - 3.9e-116 388.0 0.3 4.8e-116 387.7 0.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.14 GAO86447.1 - 2.3e-09 36.7 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.6 GAO86447.1 - 6.4e-07 28.9 0.1 6.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) MFS_1 PF07690.11 GAO86449.1 - 8.7e-31 106.8 32.5 8.7e-31 106.8 22.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86449.1 - 6.8e-11 41.3 12.5 6.8e-11 41.3 8.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO86449.1 - 2.3e-06 26.1 4.7 3.9e-06 25.3 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 GAO86450.1 - 7.2e-28 96.7 0.0 1.2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO86450.1 - 0.00022 21.0 0.1 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short_C2 PF13561.1 GAO86451.1 - 3.3e-30 105.6 0.0 4.1e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO86451.1 - 1.3e-27 96.8 0.0 1.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO86451.1 - 3.1e-11 43.2 0.0 4.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO86451.1 - 0.00073 19.0 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Paxillin PF03535.8 GAO86451.1 - 0.098 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Paxillin family Fungal_trans PF04082.13 GAO86453.1 - 2.7e-05 23.1 0.1 4.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 GAO86454.1 - 1.8e-59 200.9 0.0 2.1e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.16 GAO86455.1 - 1e-07 31.7 12.5 1e-07 31.7 8.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO86455.1 - 0.00058 19.6 17.8 0.0083 15.9 7.8 2.2 1 1 1 2 2 2 2 Basic region leucine zipper Tektin PF03148.9 GAO86455.1 - 0.0047 15.5 4.9 0.0063 15.1 3.4 1.1 1 0 0 1 1 1 1 Tektin family Afi1 PF07792.7 GAO86455.1 - 0.0078 16.2 1.3 0.012 15.6 0.9 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF724 PF05266.9 GAO86455.1 - 0.043 13.4 4.6 0.069 12.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 GAO86455.1 - 0.053 13.1 5.5 0.07 12.7 3.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 GAO86455.1 - 0.14 12.4 3.0 0.17 12.2 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 GAO86455.1 - 0.22 11.8 13.2 0.39 11.0 8.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Tox-ODYAM1 PF15642.1 GAO86455.1 - 0.25 9.9 3.2 0.33 9.5 2.2 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Homeobox_KN PF05920.6 GAO86456.1 - 2.9e-16 58.8 0.2 1.1e-15 57.0 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAO86456.1 - 2e-10 40.0 0.3 6.6e-10 38.4 0.2 2.0 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 GAO86456.1 - 1.2e-05 25.2 17.7 0.0071 16.5 0.7 4.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO86456.1 - 0.011 15.9 21.4 1.2 9.5 0.0 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type HTH_3 PF01381.17 GAO86456.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.3 GAO86456.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 GAO86456.1 - 0.11 12.6 0.1 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain zf-C2H2_2 PF12756.2 GAO86456.1 - 1.5 9.0 8.3 42 4.3 0.0 3.4 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 GAO86456.1 - 1.5 9.2 10.8 1.5 9.2 0.0 4.2 3 2 0 3 3 3 0 Zinc-finger double domain Ank_3 PF13606.1 GAO86457.1 - 5.1e-22 75.7 0.0 0.0011 18.9 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 GAO86457.1 - 6.2e-22 76.2 0.2 0.0002 21.0 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 GAO86457.1 - 1.8e-21 76.2 0.0 1.1e-11 44.9 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO86457.1 - 2.2e-15 56.6 0.1 1.1e-05 25.7 0.0 5.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86457.1 - 2.3e-14 53.0 0.7 0.0026 17.9 0.0 5.7 3 2 3 6 6 6 3 Ankyrin repeats (many copies) F-box-like PF12937.2 GAO86457.1 - 0.084 12.6 0.3 0.24 11.1 0.2 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 GAO86458.1 - 4.4e-12 45.3 53.9 3.5e-06 25.9 12.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86458.1 - 1.2 7.6 39.0 0.0052 15.4 9.1 2.9 2 1 1 3 3 3 0 Sugar (and other) transporter zf-H2C2_2 PF13465.1 GAO86459.1 - 9.7e-08 31.9 5.3 7.1e-07 29.2 1.0 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO86459.1 - 2e-07 30.8 3.7 0.0017 18.5 1.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO86459.1 - 1.3e-06 28.4 14.8 0.0004 20.5 1.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 GAO86459.1 - 2.3e-05 24.3 1.2 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn_clus PF00172.13 GAO86459.1 - 6.5e-05 22.7 12.3 6.5e-05 22.7 8.5 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.7 GAO86459.1 - 0.002 18.2 0.6 0.0046 17.0 0.4 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 GAO86459.1 - 0.066 13.3 2.2 0.95 9.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RecO_C PF02565.10 GAO86459.1 - 0.11 12.3 0.4 0.4 10.5 0.1 2.0 2 0 0 2 2 2 0 Recombination protein O C terminal LigB PF02900.13 GAO86460.1 - 2.9e-23 82.2 0.2 3.6e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Aldedh PF00171.17 GAO86461.1 - 1.1e-17 63.4 0.1 3.1e-17 62.0 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Cupin_2 PF07883.6 GAO86463.1 - 7.4e-11 41.4 0.0 1.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAO86463.1 - 0.0034 16.7 0.1 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAO86463.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Peptidase_S15 PF02129.13 GAO86464.1 - 4.1e-41 141.2 0.4 5.5e-41 140.7 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAO86464.1 - 9.4e-41 140.0 0.1 1.5e-40 139.4 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 GAO86464.1 - 2.1e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO86464.1 - 4.6e-05 23.4 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO86464.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF490 PF04357.8 GAO86464.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF490) Asp_protease PF09668.5 GAO86465.1 - 1.2e-60 202.4 0.2 2e-60 201.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease FAD_binding_3 PF01494.14 GAO86465.1 - 5.3e-19 68.4 0.1 5.3e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain ADC PF06314.6 GAO86465.1 - 2.6e-12 46.6 0.0 5e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) Asp_protease_2 PF13650.1 GAO86465.1 - 7.1e-11 42.4 0.0 2.1e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DAO PF01266.19 GAO86465.1 - 1.7e-10 40.3 4.5 3.7e-07 29.3 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase ubiquitin PF00240.18 GAO86465.1 - 4.5e-10 38.7 0.0 1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family NAD_binding_8 PF13450.1 GAO86465.1 - 3.6e-08 33.2 0.2 9.8e-08 31.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UBA PF00627.26 GAO86465.1 - 3.9e-07 29.7 0.0 9.2e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Pyr_redox_2 PF07992.9 GAO86465.1 - 6.9e-07 29.3 0.4 4.3e-06 26.7 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RVP_2 PF08284.6 GAO86465.1 - 1.9e-06 27.8 0.1 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 GAO86465.1 - 4.3e-06 26.4 0.5 1.7e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FAD_binding_2 PF00890.19 GAO86465.1 - 1.5e-05 24.0 0.4 2.5e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAO86465.1 - 6.3e-05 22.2 0.4 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 GAO86465.1 - 7.7e-05 21.9 0.2 0.00016 20.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO86465.1 - 0.00023 20.9 0.7 0.0026 17.5 0.5 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO86465.1 - 0.00025 21.3 0.2 0.0009 19.5 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO86465.1 - 0.0011 17.9 0.2 0.0023 16.8 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO86465.1 - 0.0018 16.9 1.1 0.0042 15.7 0.2 1.9 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 GAO86465.1 - 0.0021 16.6 0.3 0.0052 15.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Rad60-SLD PF11976.3 GAO86465.1 - 0.0024 17.4 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 GAO86465.1 - 0.0026 17.6 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Thi4 PF01946.12 GAO86465.1 - 0.0043 16.1 0.1 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 GAO86465.1 - 0.0044 16.4 0.3 0.0094 15.4 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 GAO86465.1 - 0.0077 15.1 0.5 0.098 11.5 0.3 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 GAO86465.1 - 0.0088 16.2 1.1 1.2 9.3 0.0 2.9 3 0 0 3 3 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 GAO86465.1 - 0.015 15.3 0.2 0.061 13.3 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_4 PF14555.1 GAO86465.1 - 0.043 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_18 PF12847.2 GAO86465.1 - 0.11 13.0 0.4 0.68 10.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF2781 PF10914.3 GAO86466.1 - 1.9e-43 147.8 12.6 2.2e-43 147.6 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) TauD PF02668.11 GAO86467.1 - 8.5e-47 159.9 0.0 1e-46 159.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_C PF03177.9 GAO86468.1 - 2.3e-144 482.1 4.9 2.9e-144 481.7 3.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAO86468.1 - 5.3e-87 292.2 0.0 7.2e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 GAO86469.1 - 8.3e-18 64.6 4.7 1e-17 64.3 3.2 1.2 1 0 0 1 1 1 1 Yqey-like protein PLU-1 PF08429.6 GAO86469.1 - 0.025 13.4 1.3 0.031 13.1 0.9 1.1 1 0 0 1 1 1 0 PLU-1-like protein NUC129 PF08157.6 GAO86469.1 - 0.033 14.1 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 NUC129 domain FAM92 PF06730.6 GAO86469.1 - 0.33 10.2 4.1 1.4 8.2 2.8 1.8 1 1 0 1 1 1 0 FAM92 protein TerB-C PF15615.1 GAO86469.1 - 0.33 11.2 4.6 0.59 10.3 3.2 1.5 1 1 0 1 1 1 0 TerB-C domain CM_2 PF01817.16 GAO86469.1 - 0.33 11.0 3.2 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Chorismate mutase type II Rot1 PF10681.4 GAO86470.1 - 7.7e-93 309.7 0.0 8.7e-93 309.5 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 GAO86470.1 - 0.15 12.7 0.0 0.53 10.9 0.0 1.7 1 1 1 2 2 2 0 Lipocalin-like domain 5-FTHF_cyc-lig PF01812.15 GAO86471.1 - 1.1e-34 119.8 0.0 1.9e-34 119.1 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 GAO86472.1 - 6e-16 57.7 0.1 7.2e-16 57.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain PP1_inhibitor PF05361.7 GAO86472.1 - 0.04 13.5 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor PhnA PF03831.9 GAO86472.1 - 0.13 11.7 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 PhnA protein Xpo1 PF08389.7 GAO86473.1 - 1.3e-25 90.0 0.4 3.2e-24 85.5 0.2 3.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 GAO86473.1 - 8.7e-06 25.5 0.2 0.00093 19.0 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 GAO86473.1 - 0.0015 16.9 0.9 0.28 9.4 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 GAO86473.1 - 0.0027 17.9 0.2 0.025 14.8 0.0 2.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 GAO86473.1 - 0.0061 16.5 0.2 0.78 9.9 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 GAO86473.1 - 0.021 15.3 0.4 0.57 10.7 0.0 3.9 5 0 0 5 5 5 0 HEAT-like repeat TerB PF05099.8 GAO86473.1 - 0.065 12.9 0.2 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Tellurite resistance protein TerB Fungal_trans PF04082.13 GAO86474.1 - 2.4e-66 223.2 0.1 3.5e-66 222.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO86474.1 - 8e-05 22.7 13.7 0.0019 18.4 1.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO86474.1 - 0.00074 19.6 13.2 0.0019 18.3 1.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO86474.1 - 0.0062 16.7 7.8 0.035 14.4 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain MGC-24 PF05283.6 GAO86474.1 - 0.8 9.4 4.3 0.91 9.2 1.9 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EF-hand_7 PF13499.1 GAO86475.1 - 2.7e-15 56.2 0.1 2.7e-10 40.2 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAO86475.1 - 3.8e-13 48.1 0.3 7.8e-05 22.2 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 GAO86475.1 - 1e-11 43.2 0.5 0.00046 19.2 0.0 3.9 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 GAO86475.1 - 2.2e-09 37.1 0.0 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 GAO86475.1 - 6.3e-08 32.1 0.2 0.00054 19.5 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAO86475.1 - 0.0011 18.2 2.2 2.2 7.7 0.7 3.3 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 GAO86475.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 GAO86475.1 - 0.057 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Yippee-Mis18 PF03226.9 GAO86476.1 - 0.027 14.5 2.5 4.1 7.5 0.5 2.5 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2330 PF10092.4 GAO86476.1 - 0.048 12.5 0.1 0.083 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Eapp_C PF10238.4 GAO86476.1 - 0.16 11.8 3.6 5.8 6.8 0.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Di19_C PF14571.1 GAO86476.1 - 0.31 11.3 9.4 1.5 9.2 0.4 2.2 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Pex14_N PF04695.8 GAO86476.1 - 0.32 11.0 6.3 7.5 6.6 3.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region E7 PF00527.13 GAO86476.1 - 3.6 7.7 12.9 0.3 11.2 0.7 2.8 3 1 0 3 3 3 0 E7 protein, Early protein zf-DHHC PF01529.15 GAO86476.1 - 4 6.7 9.1 0.42 9.9 2.6 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase PAT1 PF09770.4 GAO86476.1 - 7 4.7 16.6 8.6 4.4 11.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_RNA_Pol_19 PF05320.7 GAO86476.1 - 8 6.1 7.2 4.6 6.9 2.1 2.0 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Peptidase_M3 PF01432.15 GAO86477.1 - 1.6e-169 564.8 0.1 3.3e-169 563.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 SUV3_C PF12513.3 GAO86477.1 - 0.016 14.6 0.0 0.058 12.8 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal HpcH_HpaI PF03328.9 GAO86478.1 - 2e-33 115.1 0.0 2.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Response_reg PF00072.19 GAO86478.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain FA_desaturase PF00487.19 GAO86479.1 - 9.8e-21 74.3 13.1 9.8e-21 74.3 9.1 1.9 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAO86479.1 - 1.3e-17 63.3 0.1 3.1e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.15 GAO86480.1 - 3.6e-67 226.5 32.4 1.1e-66 224.9 22.5 1.6 1 1 0 1 1 1 1 Permease family MOSC PF03473.12 GAO86481.1 - 3.5e-13 49.1 0.0 7.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 GAO86481.1 - 8.2e-08 31.9 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rad51 PF08423.6 GAO86482.1 - 3.3e-11 42.5 0.0 1.1e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 GAO86482.1 - 2.6e-07 30.0 0.0 5.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 GAO86482.1 - 1.5e-06 27.5 0.0 2.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 GAO86482.1 - 5e-06 26.0 0.5 3.3e-05 23.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAO86482.1 - 1.9e-05 24.2 0.2 0.00014 21.4 0.0 2.2 2 1 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 GAO86482.1 - 2.6e-05 23.6 0.0 6.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 GAO86482.1 - 0.0022 18.2 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 GAO86482.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 GAO86482.1 - 0.019 15.1 0.0 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAO86482.1 - 0.026 14.2 0.2 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 GAO86482.1 - 0.05 13.4 0.1 0.26 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 GAO86482.1 - 0.054 12.7 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 GAO86482.1 - 0.11 12.1 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 GAO86482.1 - 0.12 11.9 0.1 0.34 10.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAO86482.1 - 0.12 11.4 0.5 0.35 9.9 0.0 1.9 3 0 0 3 3 3 0 Zeta toxin Arch_ATPase PF01637.13 GAO86482.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase TIP49 PF06068.8 GAO86482.1 - 0.14 10.8 0.2 0.3 9.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus NB-ARC PF00931.17 GAO86482.1 - 0.15 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Proteasome PF00227.21 GAO86484.1 - 3.7e-56 189.4 0.0 5.9e-32 110.5 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 GAO86484.1 - 1.8e-11 43.1 0.3 4.2e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 GAO86485.1 - 9.7e-09 35.1 5.2 2e-08 34.1 1.2 2.4 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 GAO86485.1 - 0.0048 16.7 4.9 0.016 15.0 1.4 2.3 2 0 0 2 2 2 1 Ring finger domain DUF1206 PF06724.6 GAO86485.1 - 0.058 13.1 1.9 0.16 11.7 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) YorP PF09629.5 GAO86486.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 YorP protein Amidohydro_2 PF04909.9 GAO86487.1 - 1.2e-42 146.3 0.6 1.5e-42 146.0 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 GAO86488.1 - 4.6e-51 173.8 26.6 3.3e-40 138.0 10.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO86488.1 - 4.3e-05 22.4 38.1 0.00012 20.8 12.6 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily His_Phos_1 PF00300.17 GAO86489.1 - 9.8e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 GAO86490.1 - 3.8e-77 258.3 0.1 6.7e-77 257.5 0.1 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAO86490.1 - 2.6e-34 118.6 0.2 9.1e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RRM_6 PF14259.1 GAO86490.1 - 9.2e-19 67.1 0.0 3.8e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO86490.1 - 4.4e-18 64.6 0.0 3.7e-12 45.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86490.1 - 4.3e-10 39.2 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.1 GAO86490.1 - 1.8e-07 31.1 0.3 2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 GAO86490.1 - 1.3e-06 27.8 0.4 3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Laminin_G_2 PF02210.19 GAO86490.1 - 0.059 13.4 0.2 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Laminin G domain Mastoparan_2 PF08251.6 GAO86490.1 - 0.19 11.8 0.8 0.47 10.5 0.5 1.7 1 0 0 1 1 1 0 Mastoparan peptide Vps39_1 PF10366.4 GAO86491.1 - 1.1e-35 121.8 0.0 8.9e-34 115.7 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 GAO86491.1 - 3e-34 117.4 0.0 6.8e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 GAO86491.1 - 1.1e-18 67.6 0.0 3.8e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 GAO86491.1 - 5.4e-09 35.7 1.5 3.3e-07 29.9 0.7 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_11 PF13414.1 GAO86491.1 - 0.077 12.6 0.5 2.8 7.6 0.0 3.5 3 1 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 GAO86491.1 - 0.26 10.9 3.7 19 5.0 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.5 GAO86492.1 - 2.2e-23 82.1 1.4 3.8e-23 81.4 1.0 1.4 1 1 0 1 1 1 1 Gon7 family DUF1423 PF07227.6 GAO86492.1 - 0.0025 16.5 1.2 0.0027 16.4 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) PBP_sp32 PF07222.7 GAO86492.1 - 0.17 11.0 2.0 0.18 10.9 1.4 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 HbrB PF08539.6 GAO86493.1 - 2.1e-60 203.1 0.0 3e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Myb_DNA-bind_5 PF13873.1 GAO86494.1 - 8.3e-05 22.4 3.8 0.085 12.7 0.2 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAO86494.1 - 0.00079 19.5 1.8 0.022 14.8 0.1 2.2 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 GAO86494.1 - 0.0036 17.9 0.9 0.26 11.9 0.1 2.2 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO86494.1 - 0.053 13.6 0.3 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA PF00004.24 GAO86495.1 - 2.2e-16 60.2 0.0 7.5e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAO86495.1 - 2.4e-05 23.9 0.1 7.4e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAO86495.1 - 0.00017 21.7 0.9 0.0033 17.5 0.6 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAO86495.1 - 0.00056 19.6 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAO86495.1 - 0.0083 16.9 0.2 0.066 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO86495.1 - 0.012 15.5 2.6 0.016 15.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 GAO86495.1 - 0.025 14.4 2.3 0.028 14.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain Ldh_1_N PF00056.18 GAO86496.1 - 1.2e-43 148.2 0.0 6.9e-43 145.8 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAO86496.1 - 4.1e-43 147.1 0.0 6.1e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAO86496.1 - 0.00059 18.6 0.0 0.00084 18.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAO86496.1 - 0.0078 16.5 0.5 0.091 13.0 0.0 2.7 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 GAO86496.1 - 0.014 14.5 0.1 0.3 10.1 0.0 2.9 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain V-SNARE_C PF12352.3 GAO86497.1 - 2.8e-14 52.9 0.4 6.9e-14 51.6 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAO86497.1 - 0.00013 21.6 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.4 GAO86497.1 - 0.0047 15.8 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking She9_MDM33 PF05546.6 GAO86497.1 - 0.013 15.0 0.2 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family SF-assemblin PF06705.6 GAO86497.1 - 0.023 13.8 0.5 0.034 13.2 0.4 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin IncA PF04156.9 GAO86497.1 - 0.078 12.5 1.4 0.17 11.4 0.4 1.8 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 GAO86497.1 - 0.11 12.2 1.8 0.3 10.8 1.2 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 GAO86497.1 - 1.3 9.0 4.7 0.86 9.6 1.2 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil 2-oxoacid_dh PF00198.18 GAO86498.1 - 3.9e-78 261.8 0.1 6.3e-78 261.2 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAO86498.1 - 8.2e-16 57.4 1.6 2.2e-15 56.0 0.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAO86498.1 - 3.1e-13 49.1 0.4 8.8e-13 47.6 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 GAO86499.1 - 2.3e-66 223.1 3.9 3.6e-66 222.4 1.7 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 GAO86499.1 - 1.3e-54 184.1 7.9 1.3e-54 184.1 5.5 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAO86499.1 - 2.3e-31 107.1 7.4 3.2e-30 103.4 0.0 4.8 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) bcl-2I13 PF12201.3 GAO86499.1 - 0.015 14.8 1.5 5.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Bcl2-interacting killer, BH3-domain containing NAD_binding_7 PF13241.1 GAO86500.1 - 3.6e-34 117.1 0.0 6.6e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAO86500.1 - 3.2e-32 109.6 0.1 5.6e-32 108.8 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAO86500.1 - 1.1e-15 56.2 0.3 1.8e-15 55.5 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 GAO86500.1 - 0.0047 16.9 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 GAO86500.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 GAO86500.1 - 0.13 12.1 0.2 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.1 GAO86501.1 - 7.5e-42 141.7 0.1 2e-40 137.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAO86501.1 - 7.2e-36 123.6 0.0 6.6e-31 107.4 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAO86501.1 - 2.2e-06 27.3 0.2 0.00014 21.6 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Suf PF05843.9 GAO86502.1 - 0.0087 15.8 2.8 0.0087 15.8 1.9 1.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 GAO86502.1 - 0.61 8.4 2.3 0.75 8.1 1.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NicO PF03824.11 GAO86502.1 - 2.5 7.3 4.3 3.4 6.8 3.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Hid1 PF12722.2 GAO86502.1 - 4.9 4.7 7.4 6.3 4.3 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dishevelled PF02377.10 GAO86502.1 - 5.7 7.2 10.3 11 6.3 6.8 1.8 1 1 0 1 1 1 0 Dishevelled specific domain zf-ribbon_3 PF13248.1 GAO86503.1 - 0.0019 17.3 2.2 0.54 9.5 0.1 2.6 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 GAO86503.1 - 0.0064 15.7 3.7 1.3 8.4 0.3 3.1 2 1 1 3 3 3 2 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 GAO86503.1 - 0.013 15.0 1.6 1.1 8.8 0.0 3.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAO86503.1 - 0.014 15.0 1.5 1.2 8.8 0.0 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 GAO86503.1 - 0.084 12.4 3.4 1.4 8.5 0.3 2.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.2 GAO86503.1 - 7.7 6.4 11.0 1.1e+03 -0.5 0.5 3.2 1 1 1 2 2 2 0 Double zinc ribbon Gly-zipper_OmpA PF13436.1 GAO86504.1 - 9.1e-05 22.0 4.4 0.00019 21.0 3.1 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 GAO86504.1 - 0.0058 16.2 13.1 0.011 15.3 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.10 GAO86504.1 - 0.025 14.2 21.2 0.044 13.4 14.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain SR-25 PF10500.4 GAO86504.1 - 0.12 11.8 13.8 0.17 11.3 9.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gly-zipper_YMGG PF13441.1 GAO86504.1 - 0.35 10.4 17.8 0.87 9.1 12.3 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF533 PF04391.7 GAO86504.1 - 0.61 9.4 6.0 1.2 8.5 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF755 PF05501.6 GAO86504.1 - 2.1 8.3 16.6 3.4 7.7 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 GAO86504.1 - 3.9 7.2 7.1 5.7 6.7 4.9 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ABC_tran PF00005.22 GAO86505.1 - 2.7e-47 160.5 0.1 6.9e-24 84.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO86505.1 - 2.8e-16 60.3 0.1 0.0032 17.4 0.0 4.3 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAO86505.1 - 7.8e-14 51.4 0.0 8.7e-05 21.8 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAO86505.1 - 3.3e-09 37.3 3.2 9.1e-05 22.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 GAO86505.1 - 2.6e-08 33.9 0.1 0.0097 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO86505.1 - 4.7e-08 32.4 0.2 0.0032 16.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO86505.1 - 1.3e-07 32.4 0.1 0.0039 17.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 GAO86505.1 - 3.1e-07 30.6 0.0 0.0057 16.8 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO86505.1 - 1.1e-06 28.7 0.9 0.43 10.5 0.0 4.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 GAO86505.1 - 1.7e-06 28.1 0.0 0.015 15.4 0.0 3.4 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 GAO86505.1 - 3.4e-06 26.3 0.0 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 GAO86505.1 - 8.2e-06 25.3 2.3 0.12 11.8 0.0 3.3 4 0 0 4 4 2 2 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 GAO86505.1 - 8.6e-06 25.9 4.2 0.1 12.8 0.0 3.4 2 1 2 4 4 3 3 HEAT repeats AAA_18 PF13238.1 GAO86505.1 - 8.9e-06 26.0 1.5 0.24 11.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAO86505.1 - 2.5e-05 24.1 0.0 0.067 13.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAO86505.1 - 2.6e-05 23.8 0.0 0.062 12.7 0.0 3.3 4 0 0 4 4 4 1 AAA-like domain MMR_HSR1 PF01926.18 GAO86505.1 - 4.2e-05 23.4 0.0 0.029 14.3 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 GAO86505.1 - 8.7e-05 22.6 0.0 0.73 10.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 GAO86505.1 - 0.00011 21.7 0.0 0.33 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 GAO86505.1 - 0.00011 21.8 1.6 0.62 9.7 0.0 3.5 4 0 0 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAO86505.1 - 0.00012 21.9 0.1 0.34 10.8 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_15 PF13175.1 GAO86505.1 - 0.00012 21.2 2.1 1.6 7.6 0.0 4.2 3 2 2 5 5 5 1 AAA ATPase domain AAA_33 PF13671.1 GAO86505.1 - 0.00013 21.9 0.0 0.46 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 GAO86505.1 - 0.00017 21.3 0.0 0.16 11.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 GAO86505.1 - 0.00019 21.9 0.0 0.14 12.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 GAO86505.1 - 0.00024 20.9 0.0 0.13 12.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 ArgK PF03308.11 GAO86505.1 - 0.00031 19.6 0.1 0.15 10.8 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 GAO86505.1 - 0.00036 20.1 0.0 0.6 9.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 GAO86505.1 - 0.0005 18.6 0.0 0.84 8.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 GAO86505.1 - 0.00052 19.7 0.0 0.29 10.7 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 GAO86505.1 - 0.00057 19.5 0.1 2 8.2 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain ATP-synt_ab PF00006.20 GAO86505.1 - 0.00084 18.9 0.1 0.16 11.4 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 GAO86505.1 - 0.0015 18.4 0.0 0.0097 15.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 GAO86505.1 - 0.0033 16.8 0.1 2.2 7.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.1 GAO86505.1 - 0.011 16.1 10.9 3.6 8.1 0.0 5.7 5 1 1 6 6 5 0 HEAT-like repeat IstB_IS21 PF01695.12 GAO86505.1 - 0.011 15.1 0.0 6.2 6.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 GAO86505.1 - 0.012 15.3 0.2 4.7 6.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 GAO86505.1 - 0.034 13.0 0.2 5 5.9 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 GAO86505.1 - 0.036 13.2 0.0 7.4 5.6 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 GAO86505.1 - 0.038 12.9 0.0 3.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 GAO86505.1 - 0.044 12.6 0.0 0.51 9.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 GAO86505.1 - 0.045 13.3 0.3 6.4 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 GAO86505.1 - 0.091 12.2 0.1 6 6.3 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT PF02985.17 GAO86505.1 - 0.19 11.8 4.1 26 5.2 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat MMS19_C PF12460.3 GAO86505.1 - 0.2 10.3 0.0 11 4.6 0.0 3.0 2 1 2 4 4 4 0 RNAPII transcription regulator C-terminal Complex1_LYR_1 PF13232.1 GAO86507.1 - 1.3e-09 38.1 3.2 3.2e-09 36.8 2.2 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAO86507.1 - 5.7e-09 35.6 4.1 5.7e-09 35.6 2.9 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 GAO86508.1 - 2.5e-14 53.3 0.3 2.3e-10 40.7 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86508.1 - 2.4e-07 30.8 0.8 8.4e-05 22.6 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO86508.1 - 5.7e-06 26.5 0.0 0.0058 16.9 0.0 3.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO86508.1 - 0.00012 21.9 0.5 0.02 15.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.8 GAO86508.1 - 0.0022 17.5 0.3 0.015 14.8 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.25 GAO86508.1 - 0.073 12.9 1.4 1.4 8.8 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Cellulase PF00150.13 GAO86509.1 - 1.5e-31 109.6 2.1 3.2e-31 108.5 0.9 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 GAO86510.1 - 2.2e-11 43.2 1.7 1.8e-07 30.6 0.0 5.3 5 1 1 6 6 6 2 TPR repeat TPR_17 PF13431.1 GAO86510.1 - 0.00017 21.5 0.0 0.06 13.5 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO86510.1 - 0.00029 20.4 4.4 0.12 12.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO86510.1 - 0.00056 19.6 17.7 0.0035 17.1 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO86510.1 - 0.00067 19.2 1.0 10 6.1 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86510.1 - 0.00075 20.0 0.2 0.054 14.1 0.0 5.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO86510.1 - 0.0032 16.9 15.2 0.0078 15.7 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO86510.1 - 0.02 15.4 0.2 0.02 15.4 0.2 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86510.1 - 0.024 14.5 17.5 3.5 7.6 0.0 6.3 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAO86510.1 - 0.59 10.0 8.5 1.2 9.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_10 PF05971.7 GAO86511.1 - 2e-69 233.9 0.0 2.8e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 GAO86511.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO86511.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAO86511.1 - 0.00041 20.9 0.0 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAO86511.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 GAO86511.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 GAO86511.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86511.1 - 0.11 12.0 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PLDc PF00614.17 GAO86512.1 - 9.5e-14 50.6 4.2 1.1e-07 31.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAO86512.1 - 2.5e-12 46.6 0.0 2.7e-06 27.1 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Abhydrolase_2 PF02230.11 GAO86513.1 - 2.4e-25 89.2 0.0 5e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAO86513.1 - 6.8e-07 29.3 0.2 6.3e-06 26.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO86513.1 - 8.4e-05 22.3 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 GAO86514.1 - 4e-37 127.8 22.0 8.2e-37 126.8 15.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86514.1 - 2.7e-29 101.9 47.9 6.7e-26 90.8 22.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.8 GAO86515.1 - 9.4e-84 280.4 0.0 1.6e-83 279.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAO86515.1 - 9.3e-09 35.1 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO86515.1 - 5.1e-06 26.5 0.1 9.7e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86515.1 - 0.0026 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 GAO86515.1 - 0.04 12.9 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 GAO86515.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 GAO86515.1 - 0.24 10.4 0.0 0.51 9.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ResIII PF04851.10 GAO86516.1 - 4.9e-26 91.6 0.0 1.2e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAO86516.1 - 4.4e-13 48.8 0.0 9.2e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO86516.1 - 3.6e-12 46.1 0.0 6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 GAO86516.1 - 6.3e-05 21.9 0.0 0.00015 20.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 GAO86516.1 - 0.0012 17.9 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Transglut_core PF01841.14 GAO86516.1 - 0.055 13.6 0.1 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily Myb_DNA-bind_6 PF13921.1 GAO86517.1 - 0.00019 21.4 0.1 0.00064 19.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain LexA_DNA_bind PF01726.11 GAO86517.1 - 0.07 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Myb_DNA-binding PF00249.26 GAO86517.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain SWIRM PF04433.12 GAO86518.1 - 4.3e-35 119.6 0.0 9e-35 118.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAO86518.1 - 3e-07 30.3 0.0 7.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO86518.1 - 1.7e-05 24.8 0.1 6.1e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 GAO86518.1 - 0.0073 15.8 4.4 0.063 12.8 3.0 2.2 1 1 0 1 1 1 1 Zinc finger, ZZ type SR-25 PF10500.4 GAO86519.1 - 3.9 6.9 10.6 4.6 6.6 7.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA PF00004.24 GAO86520.1 - 1.6e-11 44.4 0.0 3.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO86520.1 - 2.4e-06 27.7 0.0 7.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO86520.1 - 1.2e-05 25.2 0.5 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAO86520.1 - 2.1e-05 24.2 0.0 6.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAO86520.1 - 5.9e-05 22.2 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 GAO86520.1 - 0.00017 20.4 0.0 0.00028 19.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 GAO86520.1 - 0.0011 19.8 2.0 0.0022 18.8 0.0 2.6 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.1 GAO86520.1 - 0.0028 17.3 0.2 0.0081 15.8 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain Zeta_toxin PF06414.7 GAO86520.1 - 0.0069 15.4 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 GAO86520.1 - 0.0091 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAO86520.1 - 0.0091 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAO86520.1 - 0.018 15.3 0.0 0.076 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO86520.1 - 0.019 14.9 0.0 0.086 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 GAO86520.1 - 0.036 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ETF PF01012.16 GAO86521.1 - 3.7e-43 147.0 2.8 3.7e-43 147.0 1.9 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 GAO86521.1 - 1.5e-34 117.4 0.1 3.2e-34 116.4 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.16 GAO86522.1 - 1.1e-58 198.1 6.1 2.2e-58 197.2 4.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PA26 PF04636.8 GAO86522.1 - 7.3 5.1 6.4 0.74 8.4 0.9 1.7 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF1840 PF08895.6 GAO86522.1 - 8.2 6.5 7.9 0.54 10.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SUN PF03856.8 GAO86523.1 - 2.9e-99 331.4 12.7 3.7e-99 331.0 8.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Fer4_10 PF13237.1 GAO86523.1 - 0.02 14.6 0.6 0.047 13.4 0.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain TALPID3 PF15324.1 GAO86523.1 - 5.7 4.1 6.9 8.3 3.6 4.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Upf2 PF04050.9 GAO86524.1 - 2.4e-65 219.4 19.3 2.4e-65 219.4 13.3 3.1 3 0 0 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.14 GAO86524.1 - 2.3e-59 200.3 0.0 7.9e-32 110.3 0.0 3.9 4 0 0 4 4 4 2 MIF4G domain CHCH PF06747.8 GAO86525.1 - 9e-08 31.8 3.6 1.5e-07 31.1 2.5 1.4 1 0 0 1 1 1 1 CHCH domain TPK_B1_binding PF04265.9 GAO86526.1 - 7.4e-22 76.8 0.0 1.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 GAO86526.1 - 1.7e-21 76.0 0.0 4.8e-21 74.6 0.0 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Mito_carr PF00153.22 GAO86528.1 - 2.5e-60 200.2 4.8 2.7e-21 75.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Pox_A12 PF04651.8 GAO86528.1 - 3.7 7.6 7.6 2.4 8.2 0.2 2.1 2 0 0 2 2 2 0 Poxvirus A12 protein Pol_alpha_B_N PF08418.5 GAO86528.1 - 9.5 5.6 10.9 0.45 10.0 1.8 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal UPF0121 PF03661.8 GAO86529.1 - 3.2e-13 49.4 2.4 4.8e-13 48.8 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Septin PF00735.13 GAO86530.1 - 3.1e-124 413.5 0.2 3.1e-124 413.5 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAO86530.1 - 3.9e-07 30.0 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAO86530.1 - 6.5e-05 22.1 0.3 0.00041 19.5 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAO86530.1 - 6.8e-05 23.1 3.1 0.02 15.2 0.0 3.0 3 0 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 GAO86530.1 - 0.00026 20.5 2.3 0.0029 17.0 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 GAO86530.1 - 0.0018 18.2 0.3 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 GAO86530.1 - 0.002 17.2 2.3 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 GAO86530.1 - 0.0024 17.3 2.8 0.0047 16.4 1.6 1.9 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 GAO86530.1 - 0.0039 16.5 0.1 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.1 GAO86530.1 - 0.0051 16.9 0.1 0.027 14.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 GAO86530.1 - 0.0057 17.1 0.0 0.024 15.1 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAO86530.1 - 0.0059 16.1 2.1 0.022 14.2 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.1 GAO86530.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 GAO86530.1 - 0.012 15.4 6.6 0.56 10.0 0.1 3.6 3 1 0 4 4 3 0 Dynamin family Exonuc_VII_L PF02601.10 GAO86530.1 - 0.017 14.3 5.5 0.032 13.4 3.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNA_helicase PF00910.17 GAO86530.1 - 0.03 14.4 0.8 0.65 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 GAO86530.1 - 0.057 12.9 0.3 5.6 6.4 0.0 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 GAO86530.1 - 0.088 12.5 0.1 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YlqD PF11068.3 GAO86530.1 - 0.089 12.8 10.2 0.19 11.7 7.1 1.5 1 0 0 1 1 1 0 YlqD protein AAA_24 PF13479.1 GAO86530.1 - 0.098 12.2 0.7 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 GAO86530.1 - 0.14 11.9 2.1 0.25 11.1 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 GAO86530.1 - 0.14 10.7 11.3 0.5 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 GAO86530.1 - 0.49 8.1 7.6 6.2 4.5 6.8 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 GAO86530.1 - 0.95 9.0 9.8 1.7 8.2 6.8 1.3 1 0 0 1 1 1 0 IncA protein DUF2937 PF11157.3 GAO86530.1 - 1.1 8.5 3.4 2.2 7.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Phage_GPO PF05929.6 GAO86530.1 - 1.1 8.4 6.5 1.9 7.6 4.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 GAO86530.1 - 1.8 8.3 5.3 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF342 PF03961.8 GAO86530.1 - 4.9 5.4 9.3 9.4 4.5 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SSrecog PF03531.9 GAO86531.1 - 2.4e-73 246.1 0.4 6.5e-72 241.4 0.3 2.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 GAO86531.1 - 1.4e-28 98.7 0.1 2.5e-27 94.6 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Cyt-b5 PF00173.23 GAO86532.1 - 2e-16 59.5 0.0 4.7e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 GAO86532.1 - 1.7e-15 57.2 11.3 1.7e-15 57.2 7.9 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Rax2 PF12768.2 GAO86533.1 - 1.3e-106 355.8 11.3 1.5e-99 332.8 0.0 4.9 4 1 0 4 4 4 4 Cortical protein marker for cell polarity Fungal_trans_2 PF11951.3 GAO86533.1 - 2.3e-05 23.1 0.1 0.059 11.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Kelch_4 PF13418.1 GAO86533.1 - 0.013 15.2 2.1 0.11 12.2 0.3 3.4 2 0 0 2 2 2 0 Galactose oxidase, central domain OGG_N PF07934.7 GAO86534.1 - 8.1e-39 132.2 0.1 1.5e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 GAO86534.1 - 2.6e-16 59.8 0.0 4.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAO86534.1 - 0.0021 17.6 0.0 0.0087 15.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif RRM_1 PF00076.17 GAO86535.1 - 1.7e-30 104.4 0.0 7.3e-13 47.9 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86535.1 - 7.1e-23 80.3 0.0 4.7e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86535.1 - 5.6e-18 64.5 0.0 1.2e-07 31.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_2 PF00002.19 GAO86536.1 - 3.2e-05 23.1 11.2 0.002 17.2 7.8 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ribosomal_S13_N PF08069.7 GAO86537.1 - 6.4e-30 102.7 0.1 1.2e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 GAO86537.1 - 1.9e-21 75.6 0.0 2.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 GAO86537.1 - 0.019 14.6 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.6 GAO86538.1 - 2.2e-18 66.0 0.0 7.7e-18 64.3 0.0 2.0 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.8 GAO86539.1 - 1.5e-13 49.9 0.0 2.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.17 GAO86540.1 - 5.1e-20 70.8 0.0 7.1e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86540.1 - 3.6e-17 62.0 0.0 5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86540.1 - 1.8e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.4 GAO86541.1 - 3.8e-34 118.2 0.1 3.8e-34 118.2 0.0 2.8 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.1 GAO86541.1 - 1.2e-33 115.3 4.0 1.2e-33 115.3 2.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAO86541.1 - 9.1e-28 96.2 1.1 9.1e-28 96.2 0.7 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 GAO86541.1 - 9.3e-15 53.6 7.2 7.5e-14 50.7 1.7 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 GAO86541.1 - 4.4e-10 39.1 18.9 6e-08 32.2 6.7 2.6 2 0 0 2 2 2 2 PHD-finger Trypan_PARP PF05887.6 GAO86541.1 - 5.4e-05 23.0 32.0 5.4e-05 23.0 22.2 3.9 3 1 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) zf-RING-like PF08746.6 GAO86541.1 - 1.5 8.8 17.0 0.053 13.5 1.3 2.6 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.17 GAO86541.1 - 1.8 8.3 18.0 0.064 12.9 0.9 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 GAO86541.1 - 3.1 7.5 13.4 1.8 8.3 3.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DEADboxA PF12343.3 GAO86542.1 - 0.9 9.8 9.9 0.1 12.8 3.5 2.0 2 0 0 2 2 2 0 Cold shock protein DEAD box A Peptidase_M22 PF00814.20 GAO86543.1 - 1.2e-36 126.5 0.0 2.2e-35 122.4 0.0 2.5 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 GAO86543.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 YycC-like protein APH PF01636.18 GAO86544.1 - 1.8e-06 27.8 0.0 0.0053 16.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAO86544.1 - 6.1e-06 25.7 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 GAO86544.1 - 0.00032 19.9 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 GAO86544.1 - 0.0059 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 GAO86544.1 - 0.0065 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2_3 PF14378.1 GAO86545.1 - 3.1e-51 173.6 8.1 4.7e-51 173.0 5.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 GAO86545.1 - 5.8e-07 29.2 5.3 5.8e-07 29.2 3.7 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 GAO86545.1 - 2.2e-05 24.6 1.9 2.2e-05 24.6 1.3 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal TPR_3 PF07720.7 GAO86545.1 - 0.0077 16.0 0.2 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Mito_carr PF00153.22 GAO86546.1 - 1.8e-73 242.3 0.1 7.1e-26 89.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 GAO86546.1 - 3.3e-15 54.5 4.3 1e-07 31.2 0.1 5.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 GAO86546.1 - 5.9e-14 51.9 5.0 4.3e-08 33.1 0.4 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAO86546.1 - 1.4e-13 49.0 6.8 1.1e-07 30.6 0.1 5.1 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.1 GAO86546.1 - 9.6e-12 44.3 5.8 0.017 14.7 0.0 5.2 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 GAO86546.1 - 1.3e-10 40.0 3.9 3.5e-06 26.1 0.1 4.4 5 0 0 5 5 5 2 EF hand CTP_synth_N PF06418.9 GAO86547.1 - 2.1e-115 384.5 0.0 2.9e-115 384.1 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 GAO86547.1 - 4.2e-56 189.4 0.0 6.5e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAO86547.1 - 1e-07 31.6 0.0 2.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 GAO86547.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CHORD PF04968.7 GAO86548.1 - 0.0038 17.4 1.7 0.0038 17.4 1.1 2.1 2 1 0 2 2 2 1 CHORD Sugar_tr PF00083.19 GAO86550.1 - 2.1e-80 270.4 22.3 2.5e-80 270.2 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86550.1 - 4.2e-14 52.0 34.8 1.1e-12 47.4 19.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily CMD PF02627.15 GAO86550.1 - 0.066 13.0 0.0 20 5.0 0.0 2.7 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Defensin_2 PF01097.13 GAO86551.1 - 8.5e-07 28.5 7.2 8.5e-07 28.5 5.0 3.4 2 1 0 2 2 2 1 Arthropod defensin DUF2667 PF10868.3 GAO86551.1 - 0.00038 20.7 2.9 0.00038 20.7 2.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2667) EF-hand_5 PF13202.1 GAO86552.1 - 1.5 8.3 3.7 2.3 7.7 0.5 2.3 2 0 0 2 2 2 0 EF hand Ank_4 PF13637.1 GAO86553.1 - 9.4e-06 26.0 0.6 0.13 12.8 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO86553.1 - 0.0004 20.6 0.0 0.1 12.9 0.0 4.1 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86553.1 - 0.0053 16.5 0.1 1 9.3 0.0 4.7 6 1 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.2 GAO86554.1 - 1e-25 89.9 0.0 5.5e-13 49.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86554.1 - 3.3e-18 64.4 0.2 0.0021 17.7 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAO86554.1 - 7.7e-15 54.9 0.0 0.0062 17.0 0.0 4.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86554.1 - 3.1e-14 52.6 0.2 3.7e-06 27.0 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86554.1 - 3.5e-14 51.5 0.2 0.002 18.2 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Glyco_hydro_18 PF00704.23 GAO86555.1 - 8.7e-15 55.0 0.3 6.3e-14 52.1 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_2 PF00891.13 GAO86556.1 - 1.4e-33 116.1 0.1 1.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO86556.1 - 0.00075 19.2 0.0 0.0052 16.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Syntaxin PF00804.20 GAO86556.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Syntaxin Sugar_tr PF00083.19 GAO86558.1 - 1.2e-80 271.2 23.0 1.4e-80 271.0 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86558.1 - 1.1e-39 136.1 47.2 3.5e-30 104.9 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO86558.1 - 0.009 14.4 27.9 0.0059 15.0 5.4 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_88 PF07470.8 GAO86559.1 - 7.2e-08 31.8 0.0 1.5e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.4 GAO86560.1 - 1.4e-134 448.3 0.2 2.2e-134 447.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Isochorismatase PF00857.15 GAO86560.1 - 4.6e-18 65.7 0.1 8.9e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 GAO86560.1 - 1.4e-11 43.7 0.0 3.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1967 PF09269.6 GAO86560.1 - 0.11 12.2 0.0 0.35 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Pkinase PF00069.20 GAO86561.1 - 1.1e-17 64.0 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86561.1 - 5.9e-15 55.0 0.0 1.5e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAO86561.1 - 0.025 13.6 0.1 0.076 12.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 GAO86562.1 - 2.6e-23 82.4 0.0 7.4e-23 80.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAO86562.1 - 1.8e-22 79.7 0.0 3.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAO86562.1 - 0.014 14.4 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO86562.1 - 0.016 14.9 0.5 0.068 12.8 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family FAD_binding_2 PF00890.19 GAO86563.1 - 3.1e-68 230.5 4.2 3.7e-68 230.2 2.9 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO86563.1 - 8e-08 32.2 0.3 3.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO86563.1 - 6.3e-07 28.6 0.5 2.5e-05 23.3 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO86563.1 - 4.9e-06 26.7 0.1 9.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO86563.1 - 0.00014 21.7 8.6 0.037 13.8 6.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO86563.1 - 0.00017 20.8 0.1 0.00039 19.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAO86563.1 - 0.0022 16.5 1.9 0.025 13.0 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 GAO86563.1 - 0.0047 16.0 0.1 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 GAO86563.1 - 0.022 13.6 0.6 0.08 11.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO86563.1 - 0.078 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MgtC PF02308.11 GAO86564.1 - 1.1e-37 128.8 6.2 1.9e-37 128.0 4.3 1.4 1 0 0 1 1 1 1 MgtC family APH PF01636.18 GAO86565.1 - 1.8e-19 70.4 0.1 3.2e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO86565.1 - 0.00032 20.3 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 GAO86565.1 - 0.00083 18.4 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAO86565.1 - 0.0015 17.8 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 GAO86565.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SGL PF08450.7 GAO86566.1 - 0.001 18.5 0.2 0.11 11.8 0.1 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 GAO86566.1 - 0.9 9.9 10.9 13 6.2 0.1 4.3 4 1 0 4 4 4 0 PQQ-like domain Bac_rhamnosid PF05592.6 GAO86567.1 - 4.4e-30 104.3 0.1 8.3e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAO86567.1 - 0.00013 21.5 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 GAO86567.1 - 0.1 11.3 1.8 0.17 10.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF608 HisG PF01634.13 GAO86567.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Pec_lyase_C PF00544.14 GAO86568.1 - 2.9e-23 82.3 7.0 4.5e-23 81.7 4.8 1.3 1 0 0 1 1 1 1 Pectate lyase CAP59_mtransfer PF11735.3 GAO86569.1 - 1.1e-88 296.5 0.0 2.3e-86 288.9 0.0 2.2 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyoxalase_2 PF12681.2 GAO86569.1 - 2.1e-09 37.9 0.0 5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain F-box-like PF12937.2 GAO86571.1 - 0.00028 20.5 0.1 0.0012 18.5 0.0 2.2 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 GAO86571.1 - 0.0035 17.0 0.0 0.0086 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain dUTPase PF00692.14 GAO86572.1 - 6.2e-11 41.8 0.0 9.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase adh_short PF00106.20 GAO86573.1 - 9.9e-36 123.1 0.4 1.3e-35 122.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO86573.1 - 1.2e-34 120.1 0.0 1.5e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO86573.1 - 5.3e-15 55.5 0.1 7.1e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO86573.1 - 0.015 14.7 0.1 0.041 13.3 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ferric_reduct PF01794.14 GAO86574.1 - 2.5e-22 79.2 8.3 2.5e-22 79.2 5.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO86574.1 - 1.1e-11 44.9 0.1 9.5e-09 35.3 0.0 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO86574.1 - 1.4e-10 40.9 0.1 2e-08 34.0 0.1 2.4 1 1 0 1 1 1 1 FAD-binding domain Ank_2 PF12796.2 GAO86575.1 - 1.5e-72 239.9 4.7 2.5e-15 56.5 0.1 6.7 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86575.1 - 2.3e-56 184.8 12.0 1.7e-06 27.5 0.0 13.2 14 0 0 14 14 14 10 Ankyrin repeat Ank_3 PF13606.1 GAO86575.1 - 4.4e-45 147.1 7.9 0.00013 21.8 0.0 13.3 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.1 GAO86575.1 - 3.3e-38 128.8 4.4 8.7e-07 28.9 0.1 8.6 4 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO86575.1 - 1.7e-31 108.0 5.7 6.8e-09 36.0 0.0 8.5 4 1 3 8 8 8 6 Ankyrin repeats (many copies) AAA_16 PF13191.1 GAO86575.1 - 8.2e-08 32.4 0.0 3e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAO86575.1 - 0.0023 17.6 0.0 0.0058 16.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 GAO86575.1 - 0.0065 16.6 0.0 0.022 14.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO86575.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 GAO86576.1 - 0.00022 20.0 13.8 0.00022 20.0 9.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_10 PF13673.1 GAO86578.1 - 0.00023 21.2 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO86578.1 - 0.00048 20.2 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO86578.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAO86578.1 - 0.0054 16.6 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO86578.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain UbiD PF01977.11 GAO86579.1 - 1.8e-136 454.8 0.0 2.1e-136 454.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 GAO86580.1 - 2.7e-29 101.4 0.1 3.8e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Sugar_tr PF00083.19 GAO86581.1 - 1.6e-73 247.8 20.5 2.1e-73 247.4 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86581.1 - 1.7e-16 59.8 34.3 1.2e-09 37.3 11.0 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO86581.1 - 2.2e-10 39.8 0.3 5.1e-10 38.6 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86581.1 - 1.4e-07 31.3 9.3 2.7e-07 30.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_2 PF13347.1 GAO86581.1 - 0.001 17.5 17.2 0.0034 15.8 3.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Vps39_2 PF10367.4 GAO86581.1 - 0.24 11.6 2.3 0.52 10.5 1.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.1 GAO86582.1 - 2.1e-06 27.5 21.6 1.2 9.1 0.8 8.2 8 1 0 9 9 9 3 Tetratricopeptide repeat AAA_22 PF13401.1 GAO86582.1 - 2.6e-06 27.6 2.7 7.9e-05 22.7 0.1 4.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAO86582.1 - 8.3e-06 25.9 0.0 8.3e-06 25.9 0.0 4.6 5 1 1 6 6 6 1 AAA ATPase domain NACHT PF05729.7 GAO86582.1 - 9.9e-06 25.3 1.9 0.0019 17.8 0.0 3.7 3 1 0 3 3 3 1 NACHT domain TPR_14 PF13428.1 GAO86582.1 - 0.00022 21.5 9.8 1.5 9.6 0.0 8.1 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO86582.1 - 0.00061 20.0 8.9 0.046 14.0 0.2 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_19 PF13245.1 GAO86582.1 - 0.004 16.8 0.1 0.044 13.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 GAO86582.1 - 0.013 16.2 0.0 0.11 13.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAO86582.1 - 0.026 14.7 0.2 0.32 11.2 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAO86582.1 - 0.37 10.1 2.8 3.8 6.8 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain TPR_2 PF07719.12 GAO86582.1 - 1.3 9.1 12.9 30 4.8 0.5 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAO86582.1 - 1.4 8.9 23.7 2.1 8.4 0.3 7.9 10 0 0 10 10 9 0 Tetratricopeptide repeat HSP70 PF00012.15 GAO86583.1 - 1.1e-12 46.7 0.0 1.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO86583.1 - 8.3e-09 34.4 0.0 0.0012 17.5 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Patatin PF01734.17 GAO86585.1 - 4.3e-23 82.2 0.0 1.4e-22 80.6 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 GAO86585.1 - 4.3e-14 51.8 0.1 9.2e-07 28.5 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86585.1 - 8.3e-11 41.6 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAO86585.1 - 6.2e-09 35.1 0.1 1.4e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 GAO86585.1 - 1e-07 32.1 0.1 2.7e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO86585.1 - 1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAO86585.1 - 2.9e-05 23.7 0.0 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_11 PF13414.1 GAO86585.1 - 0.0006 19.4 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 GAO86585.1 - 0.0013 18.4 0.2 0.56 10.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Pox_A32 PF04665.7 GAO86585.1 - 0.0063 15.8 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein TPR_7 PF13176.1 GAO86585.1 - 0.0063 16.2 0.1 6.3 6.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAO86585.1 - 0.0097 15.6 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase TPR_1 PF00515.23 GAO86585.1 - 0.027 14.0 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86585.1 - 0.043 14.5 0.2 0.29 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO86585.1 - 0.043 14.4 0.1 5.7 7.8 0.0 3.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO86585.1 - 0.08 13.4 0.8 0.62 10.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAO86585.1 - 0.082 12.7 0.0 2.7 7.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 GAO86587.1 - 2.4e-08 33.8 0.0 6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CDC45 PF02724.9 GAO86587.1 - 0.0051 14.9 6.5 0.0077 14.3 4.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Methyltransf_12 PF08242.7 GAO86587.1 - 0.041 14.3 0.9 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Nop14 PF04147.7 GAO86587.1 - 0.094 10.6 15.8 0.14 10.0 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 GAO86587.1 - 0.13 11.2 4.9 0.2 10.6 3.4 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 GAO86587.1 - 1.6 6.7 9.3 2.6 6.0 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Phosphoesterase PF04185.9 GAO86588.1 - 9.4e-67 225.8 1.2 1.7e-66 224.9 0.8 1.4 1 0 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.11 GAO86589.1 - 1.3e-40 139.2 29.1 1.3e-40 139.2 20.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 GAO86589.1 - 0.01 13.9 3.6 0.017 13.2 1.3 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 GAO86590.1 - 5.3e-16 58.2 0.0 8.9e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86590.1 - 1.9e-06 27.6 10.8 3.7e-06 26.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_28 PF03033.15 GAO86591.1 - 5.6e-22 78.0 0.1 1.1e-20 73.7 0.0 3.0 3 1 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAO86591.1 - 7.4e-07 28.0 0.0 1.8e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAO86591.1 - 0.00042 20.0 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain zf-Tim10_DDP PF02953.10 GAO86591.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Erf4 PF10256.4 GAO86592.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family F-box-like PF12937.2 GAO86593.1 - 7.1e-06 25.6 1.0 1.8e-05 24.3 0.7 1.8 1 0 0 1 1 1 1 F-box-like CVNH PF08881.5 GAO86594.1 - 2.1e-33 114.6 0.4 2.9e-33 114.1 0.3 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.10 GAO86594.1 - 3.6e-06 26.5 13.4 6.3e-06 25.7 9.3 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAO86594.1 - 8.1e-05 22.1 7.6 0.00014 21.3 5.3 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 GAO86594.1 - 0.0019 17.8 1.1 0.0044 16.6 0.7 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain SR-25 PF10500.4 GAO86594.1 - 0.02 14.3 4.6 0.032 13.7 3.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF533 PF04391.7 GAO86594.1 - 0.034 13.5 0.8 0.051 12.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TraT PF05818.7 GAO86594.1 - 0.043 13.2 1.3 0.068 12.5 0.9 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 GAO86594.1 - 0.12 11.8 14.0 0.22 11.0 9.7 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF755 PF05501.6 GAO86594.1 - 0.36 10.8 7.3 0.64 10.0 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 GAO86594.1 - 0.52 10.1 6.3 0.84 9.4 4.4 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF2076 PF09849.4 GAO86594.1 - 0.59 10.1 10.2 0.44 10.5 6.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RrnaAD PF00398.15 GAO86595.1 - 1.3e-62 211.2 0.0 2e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAO86595.1 - 2.1e-10 40.6 0.0 3.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO86595.1 - 5.5e-06 26.9 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO86595.1 - 3.2e-05 23.5 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 GAO86595.1 - 0.00047 19.3 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAO86595.1 - 0.00051 19.8 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO86595.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAO86595.1 - 0.0085 15.2 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 GAO86595.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_31 PF13847.1 GAO86595.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 GAO86595.1 - 0.038 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 GAO86595.1 - 0.05 13.2 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_3 PF01596.12 GAO86595.1 - 0.12 11.3 0.1 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 GAO86595.1 - 0.13 12.2 0.1 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Aldo_ket_red PF00248.16 GAO86596.1 - 5.9e-67 225.4 0.0 7.8e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dabb PF07876.7 GAO86599.1 - 1.2e-22 80.1 0.0 1.3e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 GAO86600.1 - 6.7e-11 41.5 0.1 6.7e-11 41.5 0.1 1.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86600.1 - 0.00039 20.2 0.8 0.00074 19.3 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4197 PF13852.1 GAO86600.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) Fungal_trans PF04082.13 GAO86601.1 - 8.7e-06 24.7 0.7 2.6e-05 23.2 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Git3 PF11710.3 GAO86602.1 - 2.8e-40 138.0 16.9 4.4e-40 137.4 11.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAO86602.1 - 6.8e-14 51.3 0.4 2.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 GAO86602.1 - 0.0077 15.1 13.7 0.012 14.5 9.5 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor HhH-GPD PF00730.20 GAO86604.1 - 1.5e-06 28.3 0.0 1.8e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein G_glu_transpept PF01019.16 GAO86606.1 - 6.3e-161 536.3 0.0 7.3e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 GAO86607.1 - 3.5e-15 55.5 63.0 2.3e-13 49.5 41.8 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MSP1b PF03429.8 GAO86607.1 - 0.026 12.4 0.7 0.039 11.8 0.5 1.2 1 0 0 1 1 1 0 Major surface protein 1B Glyco_hydro_92 PF07971.7 GAO86608.1 - 1.2e-163 545.4 0.9 6e-162 539.7 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 R3H PF01424.17 GAO86609.1 - 4.6e-11 42.2 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain TGS PF02824.16 GAO86609.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain Evr1_Alr PF04777.8 GAO86610.1 - 1.9e-27 94.9 1.4 3.7e-27 94.0 0.1 2.2 2 0 0 2 2 2 1 Erv1 / Alr family zf-LYAR PF08790.6 GAO86610.1 - 0.044 13.4 0.6 0.13 11.9 0.4 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger LepA_C PF06421.7 GAO86611.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus ATP11 PF06644.6 GAO86612.1 - 4.3e-97 324.7 0.0 4.9e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein zf-C4H2 PF10146.4 GAO86612.1 - 0.13 12.2 2.8 0.2 11.6 1.9 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Mito_fiss_reg PF05308.6 GAO86612.1 - 0.22 10.8 3.7 0.34 10.2 2.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Abhydrolase_5 PF12695.2 GAO86613.1 - 4.7e-22 78.3 0.0 6.9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO86613.1 - 1.2e-19 71.1 0.0 2.2e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO86613.1 - 3.2e-06 26.8 0.0 0.00032 20.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO86613.1 - 4.8e-06 25.9 0.0 1.1e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 GAO86613.1 - 5.6e-06 25.0 0.0 0.63 8.4 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 GAO86613.1 - 0.0001 21.8 0.0 0.00036 20.0 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.7 GAO86613.1 - 0.00013 20.8 0.0 0.00017 20.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 GAO86613.1 - 0.00064 19.3 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAO86613.1 - 0.0008 18.7 0.0 0.098 11.9 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAO86613.1 - 0.005 16.5 0.0 0.48 10.1 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 GAO86613.1 - 0.0056 16.2 0.1 0.06 12.9 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 GAO86613.1 - 0.0079 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 GAO86613.1 - 0.015 14.6 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 GAO86613.1 - 0.02 14.3 0.1 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAO86613.1 - 0.038 13.5 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Acyl_transf_2 PF02273.10 GAO86613.1 - 0.06 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Acyl transferase Esterase PF00756.15 GAO86613.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Proteasome PF00227.21 GAO86614.1 - 1.1e-45 155.3 0.1 1.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 GAO86614.1 - 3e-36 125.0 6.5 5.6e-22 78.7 0.1 3.2 3 1 0 3 3 3 2 Cyclin Peptidase_C48 PF02902.14 GAO86617.1 - 1.5e-13 50.8 0.0 9.1e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RhoGEF PF00621.15 GAO86618.1 - 1.1e-38 132.9 0.1 6.2e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 GAO86618.1 - 6.8e-15 55.2 3.2 1.6e-14 54.0 2.2 1.6 1 0 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.3 GAO86619.1 - 2.7e-43 147.1 1.5 5.4e-43 146.1 1.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 GAO86619.1 - 4.8e-14 52.2 0.0 2.7e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Argos PF11581.3 GAO86619.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos RabGAP-TBC PF00566.13 GAO86620.1 - 4.6e-30 104.6 0.0 6.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain E1-E2_ATPase PF00122.15 GAO86621.1 - 3.2e-49 167.0 4.0 7e-49 165.9 2.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO86621.1 - 6.2e-43 146.4 7.0 6.2e-43 146.4 4.9 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO86621.1 - 6.1e-31 108.5 0.0 1.3e-30 107.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO86621.1 - 1.2e-20 73.2 0.0 2.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO86621.1 - 1.2e-14 54.9 0.0 4.2e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO86621.1 - 2.5e-10 39.6 0.0 6.8e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAO86621.1 - 0.0002 21.0 1.5 0.00081 19.0 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 GAO86622.1 - 1.8e-50 171.5 0.0 2.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86622.1 - 1.7e-21 76.4 0.0 6.9e-21 74.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO86622.1 - 1.7e-06 27.2 0.0 8.4e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO86622.1 - 0.00052 19.1 0.2 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 GAO86623.1 - 1.5e-25 90.0 0.1 1.1e-24 87.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO86623.1 - 2.2e-19 70.2 0.3 3.9e-19 69.3 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO86623.1 - 1.4e-08 34.6 0.2 8.4e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 GAO86623.1 - 0.00041 19.5 0.7 0.00093 18.4 0.1 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 GAO86623.1 - 0.00067 19.7 0.8 0.0019 18.2 0.6 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAO86623.1 - 0.0081 15.6 0.1 0.11 11.8 0.0 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO86623.1 - 0.0093 14.8 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein STAT_int PF02865.12 GAO86623.1 - 0.064 13.2 0.0 0.53 10.2 0.0 2.1 1 1 1 2 2 2 0 STAT protein, protein interaction domain NAD_binding_10 PF13460.1 GAO86623.1 - 0.073 13.0 0.5 0.41 10.6 0.1 2.2 2 1 0 2 2 2 0 NADH(P)-binding DUF3804 PF12707.2 GAO86623.1 - 0.082 12.4 0.3 9.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) ADH_zinc_N PF00107.21 GAO86624.1 - 1.6e-24 85.8 0.1 3e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO86624.1 - 2.4e-06 28.4 0.0 4.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1938 PF09153.5 GAO86624.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Abhydrolase_6 PF12697.2 GAO86626.1 - 1.6e-05 24.8 3.2 1.7e-05 24.7 0.3 2.4 2 2 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 GAO86626.1 - 0.035 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 GAO86626.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 GAO86626.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HisG PF01634.13 GAO86627.1 - 7.3e-51 171.9 0.3 2.3e-50 170.3 0.3 1.7 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 GAO86627.1 - 8.7e-28 96.0 0.1 2.1e-27 94.8 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain Ribosomal_S28e PF01200.13 GAO86628.1 - 1.3e-33 114.5 1.9 1.4e-33 114.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 GAO86629.1 - 1.3e-89 299.6 0.0 2.5e-89 298.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO86629.1 - 6.3e-39 133.8 1.7 1.6e-38 132.5 1.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAO86629.1 - 1.4e-18 66.9 0.0 4.6e-11 42.7 0.0 2.9 1 1 1 2 2 2 2 MutS domain I MutS_II PF05188.12 GAO86629.1 - 7.2e-10 39.0 0.0 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAO86629.1 - 3.1e-07 30.4 0.0 1.3e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV Autoind_bind PF03472.10 GAO86630.1 - 0.025 13.8 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 0 Autoinducer binding domain Prenyltrans PF00432.16 GAO86631.1 - 3.2e-56 186.5 8.2 7.1e-12 44.6 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAO86631.1 - 3.7e-34 117.5 0.0 2.7e-13 50.3 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAO86631.1 - 1.1e-09 38.2 0.0 0.00086 19.2 0.0 4.0 3 1 1 4 4 4 2 Prenyltransferase-like RhoGAP PF00620.22 GAO86632.1 - 6.4e-30 103.7 0.0 1e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 GAO86633.1 - 3.5e-59 198.9 1.7 4.2e-59 198.7 1.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 GAO86634.1 - 1.3e-108 362.5 0.0 1.6e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 GAO86634.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SET PF00856.23 GAO86635.1 - 4.4e-09 36.8 0.0 2.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 GAO86635.1 - 7.7e-05 22.2 0.3 0.00018 21.0 0.2 1.6 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 GAO86635.1 - 0.012 15.1 0.1 0.033 13.7 0.1 1.8 1 0 0 1 1 1 0 SAP domain EXOSC1 PF10447.4 GAO86636.1 - 0.069 13.1 0.1 25 4.9 0.0 3.3 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 ADH_N PF08240.7 GAO86638.1 - 2.4e-26 91.6 0.7 4.3e-26 90.7 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO86638.1 - 1.2e-22 79.8 0.4 1.7e-22 79.3 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CmcI PF04989.7 GAO86638.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Amidohydro_2 PF04909.9 GAO86639.1 - 1.7e-14 54.0 0.2 1.3e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase CaATP_NAI PF12515.3 GAO86639.1 - 0.79 9.2 3.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain adh_short PF00106.20 GAO86640.1 - 5e-27 94.8 0.7 6.1e-27 94.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO86640.1 - 2e-21 76.8 0.0 2.3e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO86640.1 - 7.1e-10 38.8 0.1 1.2e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.1 GAO86641.1 - 6e-20 71.2 0.0 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAO86641.1 - 3.1e-12 46.8 0.0 5.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAO86641.1 - 5e-10 39.4 0.0 8.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 GAO86642.1 - 5.5e-26 91.0 0.1 7.7e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86642.1 - 1.9e-07 30.8 11.0 3.4e-07 30.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EcsB PF05975.7 GAO86642.1 - 0.12 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Pkinase PF00069.20 GAO86643.1 - 2.7e-70 236.4 0.0 3.9e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86643.1 - 5.9e-51 173.0 0.0 9.8e-51 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO86643.1 - 0.00069 18.6 0.0 0.027 13.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 GAO86643.1 - 9.3 4.3 17.9 13 3.8 12.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredoxin_7 PF13899.1 GAO86644.1 - 1.4e-15 57.0 0.0 2.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 GAO86644.1 - 2.8e-14 52.3 0.1 6.3e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAO86644.1 - 1.9e-07 31.0 0.0 7.1e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.1 GAO86644.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 GAO86644.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 CENP-K PF11802.3 GAO86644.1 - 0.042 13.0 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K AAA_16 PF13191.1 GAO86645.1 - 3.6e-14 53.1 0.9 6.4e-13 49.1 0.7 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO86645.1 - 8.5e-13 48.5 0.0 2.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAO86645.1 - 7.4e-12 45.6 0.0 2.3e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 GAO86645.1 - 1.2e-06 28.0 0.0 3.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_17 PF13207.1 GAO86645.1 - 0.0033 18.2 0.0 0.0056 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 GAO86645.1 - 0.0043 16.7 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 NTPase DUF815 PF05673.8 GAO86645.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.9 GAO86645.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 GAO86645.1 - 0.023 14.4 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 GAO86645.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 GAO86645.1 - 0.04 14.0 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 GAO86645.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAO86645.1 - 0.058 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 GAO86645.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 GAO86646.1 - 2.4e-16 59.6 0.2 7.1e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAO86646.1 - 3.7e-13 49.4 0.0 1.9e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 GAO86646.1 - 4.1e-10 39.2 0.0 8.2e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease PF00324.16 GAO86647.1 - 1.4e-144 482.0 42.7 1.7e-144 481.7 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO86647.1 - 7.8e-35 120.2 43.4 1e-34 119.8 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 GAO86648.1 - 3.4e-21 74.5 0.0 3.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 GAO86649.1 - 3e-19 69.1 0.0 4.6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.9 GAO86650.1 - 4.5e-44 150.5 7.8 5.7e-44 150.2 5.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 GAO86650.1 - 4.6e-11 42.3 9.6 7.6e-11 41.6 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAO86650.1 - 5.5e-11 41.9 7.5 8.6e-11 41.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO86650.1 - 7.4e-11 41.8 9.3 1.2e-10 41.2 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO86650.1 - 9e-10 38.0 6.1 1.5e-09 37.4 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO86650.1 - 1e-08 34.7 6.6 1.7e-08 34.0 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAO86650.1 - 2.6e-06 27.1 8.6 4.6e-06 26.4 6.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAO86650.1 - 4e-06 26.4 3.1 4.6e-06 26.2 0.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAO86650.1 - 9.5e-05 22.4 7.7 0.0002 21.4 5.3 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 GAO86650.1 - 0.00081 19.1 3.2 0.0015 18.2 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 GAO86650.1 - 0.0061 16.5 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-Apc11 PF12861.2 GAO86650.1 - 0.011 15.5 1.9 0.019 14.7 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 GAO86650.1 - 0.059 12.5 1.7 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.1 GAO86650.1 - 0.11 12.1 7.6 0.22 11.1 5.3 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 GAO86650.1 - 0.16 11.5 4.0 0.32 10.5 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 GAO86650.1 - 1.9 8.3 7.8 6.9 6.6 5.4 1.9 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 GAO86651.1 - 1.6e-99 333.2 5.9 1.8e-99 333.0 4.1 1.0 1 0 0 1 1 1 1 EXS family TRAP_alpha PF03896.11 GAO86652.1 - 0.11 11.4 1.0 0.17 10.8 0.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit IER PF05760.7 GAO86652.1 - 0.44 10.4 7.6 0.93 9.3 5.3 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Macoilin PF09726.4 GAO86652.1 - 0.78 7.9 5.6 0.92 7.7 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.12 GAO86652.1 - 3 6.5 5.3 4.7 5.9 3.7 1.2 1 0 0 1 1 1 0 Presenilin ATP-synt_S1 PF05827.7 GAO86653.1 - 6e-62 209.5 0.0 7e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.8 GAO86653.1 - 0.0034 17.7 0.2 0.0059 16.9 0.2 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Nop25 PF09805.4 GAO86654.1 - 6.8e-38 129.8 17.8 6.8e-38 129.8 12.3 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.2 GAO86655.1 - 1e-50 171.3 38.0 1.2e-50 171.1 26.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 GAO86655.1 - 3.2e-10 39.5 34.6 2.5e-06 26.7 14.2 2.6 1 1 1 2 2 2 2 Tropomyosin Mod_r PF07200.8 GAO86655.1 - 0.00098 19.0 26.5 0.058 13.3 13.9 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein KLRAQ PF10205.4 GAO86655.1 - 0.0012 18.9 9.5 0.0012 18.9 6.6 2.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF4200 PF13863.1 GAO86655.1 - 0.0057 16.6 32.0 0.0084 16.0 11.7 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Laminin_II PF06009.7 GAO86655.1 - 0.0078 15.9 7.6 0.0078 15.9 5.2 2.2 1 1 1 2 2 2 1 Laminin Domain II ADIP PF11559.3 GAO86655.1 - 0.009 15.9 31.9 0.24 11.3 8.3 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 GAO86655.1 - 0.01 15.7 30.8 0.075 12.9 0.6 4.3 1 1 3 4 4 4 0 bZIP transcription factor Cast PF10174.4 GAO86655.1 - 0.011 13.8 28.9 0.013 13.6 20.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 GAO86655.1 - 0.015 15.1 28.6 0.46 10.2 7.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MAD PF05557.8 GAO86655.1 - 0.017 13.2 23.4 0.023 12.8 16.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.3 GAO86655.1 - 0.018 14.7 29.2 0.76 9.5 12.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 GAO86655.1 - 0.021 14.0 3.1 0.22 10.6 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Striatin PF08232.7 GAO86655.1 - 0.023 15.0 26.6 0.7 10.2 13.7 2.3 1 1 0 2 2 2 0 Striatin family GAS PF13851.1 GAO86655.1 - 0.023 13.8 29.3 0.056 12.6 14.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 GAO86655.1 - 0.039 14.0 20.5 2.9 8.0 0.3 3.0 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 GAO86655.1 - 0.046 13.3 32.5 29 4.2 22.5 2.2 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 GAO86655.1 - 0.074 12.0 34.1 0.2 10.6 10.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 GAO86655.1 - 0.088 12.3 33.7 0.07 12.6 9.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 GAO86655.1 - 0.13 12.3 17.3 0.28 11.2 4.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 GAO86655.1 - 0.17 12.3 19.4 9.6 6.6 6.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal EzrA PF06160.7 GAO86655.1 - 0.17 10.0 23.9 0.015 13.5 2.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2730 PF10805.3 GAO86655.1 - 0.24 11.1 16.7 0.38 10.5 2.8 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.14 GAO86655.1 - 0.27 9.0 17.7 0.41 8.4 12.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 GAO86655.1 - 0.27 10.1 26.4 1.3 7.8 18.3 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.4 GAO86655.1 - 0.32 10.9 27.9 0.65 9.9 12.1 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IFT46_B_C PF12317.3 GAO86655.1 - 0.34 10.2 9.2 0.052 12.9 3.2 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 GAO86655.1 - 0.37 9.3 26.2 1.1 7.8 5.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3287 PF11690.3 GAO86655.1 - 0.47 10.5 7.9 0.41 10.7 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) WXG100 PF06013.7 GAO86655.1 - 0.48 10.4 15.8 4.1 7.4 0.1 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG RdRP_4 PF02123.11 GAO86655.1 - 0.61 8.7 8.3 0.7 8.5 5.8 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase AAA_13 PF13166.1 GAO86655.1 - 0.65 8.3 23.8 1.3 7.3 16.5 1.5 1 1 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.4 GAO86655.1 - 0.83 7.9 24.1 0.28 9.5 6.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.3 GAO86655.1 - 1 9.2 37.8 5.6 6.8 4.4 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 GAO86655.1 - 1.1 9.6 24.9 0.61 10.4 9.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 GAO86655.1 - 1.2 8.7 25.3 1.2 8.8 1.2 3.6 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.17 GAO86655.1 - 1.4 8.9 28.5 3.3 7.7 0.2 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 GAO86655.1 - 1.4 8.7 32.7 69 3.2 15.8 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NABP PF07990.7 GAO86655.1 - 1.4 8.1 6.0 1.5 7.9 4.2 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4201 PF13870.1 GAO86655.1 - 1.4 8.2 27.3 9 5.6 18.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FlxA PF14282.1 GAO86655.1 - 1.6 8.7 22.5 12 5.9 0.1 2.9 1 1 2 3 3 3 0 FlxA-like protein FUSC PF04632.7 GAO86655.1 - 1.6 7.0 8.7 1.7 6.9 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 GAO86655.1 - 1.8 5.8 29.5 7.2 3.7 20.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF904 PF06005.7 GAO86655.1 - 1.8 8.8 38.0 0.78 10.0 4.6 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF904) TMCO5 PF14992.1 GAO86655.1 - 1.9 7.5 26.9 1.8 7.6 11.3 2.1 1 1 1 2 2 2 0 TMCO5 family Surfac_D-trimer PF09006.6 GAO86655.1 - 2 8.2 7.1 3 7.6 0.0 3.8 5 0 0 5 5 3 0 Lung surfactant protein D coiled-coil trimerisation DUF724 PF05266.9 GAO86655.1 - 2.2 7.8 25.3 0.59 9.7 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Sec8_exocyst PF04048.9 GAO86655.1 - 2.2 7.9 13.5 27 4.3 3.2 2.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF2721 PF11026.3 GAO86655.1 - 2.2 7.8 5.9 10 5.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Lebercilin PF15619.1 GAO86655.1 - 2.6 7.4 32.6 9.4 5.5 16.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF342 PF03961.8 GAO86655.1 - 3.8 5.7 24.8 0.31 9.3 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 GAO86655.1 - 4 7.0 32.1 0.7 9.4 14.2 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Uds1 PF15456.1 GAO86655.1 - 4 7.4 26.2 10 6.1 12.4 2.6 1 1 1 2 2 2 0 Up-regulated During Septation Phage_GP20 PF06810.6 GAO86655.1 - 5 6.5 29.6 0.85 9.0 10.4 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 HSP70 PF00012.15 GAO86655.1 - 5.5 4.7 18.9 7.5 4.3 13.1 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF3450 PF11932.3 GAO86655.1 - 7.5 5.7 26.6 13 4.9 10.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 GAO86655.1 - 7.8 6.4 16.4 4.6 7.2 1.3 4.2 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) CMAS PF02353.15 GAO86657.1 - 8.1e-63 212.0 0.0 1e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAO86657.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO86657.1 - 7.4e-05 23.1 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 GAO86657.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 GAO86657.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO86657.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 GAO86657.1 - 0.015 15.9 0.1 0.038 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAO86657.1 - 0.04 14.3 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAO86657.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cu_amine_oxid PF01179.15 GAO86658.1 - 2.5e-171 570.0 0.6 2.9e-171 569.7 0.4 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAO86658.1 - 2.5e-07 30.6 0.2 5.3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAO86658.1 - 0.00032 20.7 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Pex24p PF06398.6 GAO86659.1 - 3.3e-103 345.2 2.2 4.1e-103 344.9 1.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Syntaxin-18_N PF10496.4 GAO86659.1 - 0.15 11.9 0.3 0.36 10.7 0.2 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Pam16 PF03656.8 GAO86660.1 - 2.9e-36 124.0 0.8 3.6e-36 123.7 0.6 1.0 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.16 GAO86661.1 - 1.2e-66 224.4 0.0 1.5e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1539 PF07560.6 GAO86661.1 - 0.0082 16.0 0.0 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) PAP_assoc PF03828.14 GAO86662.1 - 1.6e-16 60.0 0.6 3.2e-16 58.9 0.4 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAO86662.1 - 1.2e-07 31.9 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.9 GAO86663.1 - 1.1e-23 82.9 5.5 2e-13 50.1 0.6 2.6 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 GAO86663.1 - 0.13 11.8 2.6 4 7.0 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 GAO86663.1 - 0.62 9.9 5.4 13 5.7 0.2 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PRKCSH-like PF12999.2 GAO86664.1 - 3.2e-45 153.8 16.2 8.1e-28 97.1 3.7 3.2 2 1 1 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 GAO86664.1 - 1.6e-31 108.8 1.0 1.6e-31 108.8 0.7 2.8 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 GAO86664.1 - 1.2e-11 45.2 0.2 5.7e-11 43.0 0.2 2.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein EMP24_GP25L PF01105.19 GAO86664.1 - 0.047 13.4 0.4 0.047 13.4 0.3 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.7 GAO86664.1 - 1.7 9.0 7.5 42 4.6 1.4 3.5 3 0 0 3 3 3 0 SlyX DUF2500 PF10694.4 GAO86664.1 - 1.7 8.6 4.2 3.2 7.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) PspA_IM30 PF04012.7 GAO86664.1 - 2.4 7.4 24.2 2.8 7.2 9.4 3.0 2 1 0 3 3 3 0 PspA/IM30 family DUF342 PF03961.8 GAO86664.1 - 2.7 6.3 17.1 7.4 4.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) GrpE PF01025.14 GAO86664.1 - 2.8 7.4 22.3 5.5 6.4 9.9 2.9 2 1 0 2 2 2 0 GrpE Fib_alpha PF08702.5 GAO86664.1 - 5.4 7.1 14.0 8.5 6.4 0.1 2.7 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.16 GAO86664.1 - 6.4 6.1 25.7 1.4 8.2 2.1 3.0 2 1 1 3 3 3 0 Intermediate filament protein Rtf2 PF04641.7 GAO86665.1 - 4.2e-73 245.7 2.2 5.2e-73 245.4 1.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 GAO86665.1 - 5.9e-09 35.3 0.3 0.0006 19.2 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAO86665.1 - 3.9e-08 32.8 0.4 1.3e-07 31.2 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 GAO86665.1 - 0.0011 18.6 0.1 0.0025 17.4 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAO86665.1 - 0.009 15.6 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO86665.1 - 0.032 14.0 0.4 0.12 12.1 0.1 2.1 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 GAO86665.1 - 0.043 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thiolase_N PF00108.18 GAO86666.1 - 2.5e-81 272.5 0.1 3.8e-81 271.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO86666.1 - 7.6e-44 148.0 1.2 1.5e-43 147.1 0.8 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Ribosomal_L50 PF10501.4 GAO86666.1 - 6.2e-34 116.3 0.1 1.2e-33 115.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S DAHP_synth_1 PF00793.15 GAO86668.1 - 1.3e-95 319.1 0.0 1.6e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 GAO86669.1 - 6.9e-20 70.4 0.7 6.9e-20 70.4 0.5 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1178 PF06676.6 GAO86669.1 - 0.079 13.1 0.0 0.079 13.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) DUF2458 PF10454.4 GAO86670.1 - 4.1e-55 185.7 5.0 5.6e-55 185.3 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) NAD_binding_4 PF07993.7 GAO86670.1 - 0.019 13.9 0.6 0.038 12.9 0.4 1.5 1 1 0 1 1 1 0 Male sterility protein DUF964 PF06133.6 GAO86670.1 - 0.85 9.6 4.8 4.6 7.2 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF964) Hexokinase_2 PF03727.11 GAO86671.1 - 1.4e-34 119.3 0.0 1.1e-31 109.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAO86671.1 - 2.7e-33 115.0 0.0 3.7e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF3285 PF11688.3 GAO86672.1 - 0.045 13.3 0.1 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Abhydrolase_6 PF12697.2 GAO86673.1 - 0.0034 17.2 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO86673.1 - 0.011 15.3 0.0 0.22 11.0 0.0 2.3 1 1 0 1 1 1 0 PGAP1-like protein Arylsulfotran_2 PF14269.1 GAO86674.1 - 1.1e-46 159.3 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO86674.1 - 3.8e-13 48.7 0.7 1.2e-11 43.8 0.5 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) ADK PF00406.17 GAO86676.1 - 3.2e-41 140.6 0.1 1.2e-40 138.8 0.1 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 GAO86676.1 - 4.9e-09 36.5 0.0 8.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO86676.1 - 1.2e-07 32.5 0.0 1.9e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO86676.1 - 1.5e-07 31.4 0.0 4.7e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAO86676.1 - 8.3e-06 25.3 0.2 0.011 15.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 GAO86676.1 - 0.0073 15.4 0.1 0.021 13.8 0.1 1.9 1 1 0 1 1 1 1 Zeta toxin PCI PF01399.22 GAO86677.1 - 1.6e-10 41.2 0.0 4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain Imm2 PF14426.1 GAO86677.1 - 0.018 15.0 0.0 0.87 9.6 0.0 3.1 3 0 0 3 3 3 0 Immunity protein Imm2 RNase_P_Rpp14 PF01900.14 GAO86677.1 - 0.03 14.2 0.1 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family SurA_N_2 PF13623.1 GAO86677.1 - 0.13 12.2 0.1 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 SurA N-terminal domain MSG PF02349.10 GAO86678.1 - 0.0076 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Major surface glycoprotein Plasmodium_Vir PF05795.6 GAO86678.1 - 0.076 12.2 2.1 0.091 11.9 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TT_ORF1 PF02956.9 GAO86678.1 - 0.15 10.5 0.9 0.18 10.1 0.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 FmdE PF02663.9 GAO86678.1 - 0.17 11.8 0.8 0.48 10.3 0.6 2.0 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Rifin_STEVOR PF02009.11 GAO86678.1 - 0.49 9.9 6.9 0.66 9.5 4.8 1.2 1 0 0 1 1 1 0 Rifin/stevor family Dicty_REP PF05086.7 GAO86678.1 - 0.68 7.6 4.8 0.88 7.2 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 GAO86678.1 - 0.96 7.2 7.8 1.3 6.8 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_viral_N PF00242.12 GAO86678.1 - 1.1 8.2 6.1 1.3 7.9 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 GAO86678.1 - 3.2 5.9 7.8 3.5 5.7 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Herpes_capsid PF06112.6 GAO86678.1 - 7.6 6.5 16.5 14 5.7 11.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein 4HBT PF03061.17 GAO86679.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_transf_20 PF00982.16 GAO86680.1 - 4.4e-156 520.0 0.0 6.6e-156 519.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 4HBT_3 PF13622.1 GAO86680.1 - 1.1e-58 199.0 3.7 1.1e-58 199.0 2.6 2.6 3 0 0 3 3 3 1 Thioesterase-like superfamily Trehalose_PPase PF02358.11 GAO86680.1 - 2.6e-39 134.5 0.0 4e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 GAO86680.1 - 0.037 13.5 0.0 0.6 9.6 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Stk19 PF10494.4 GAO86681.1 - 5.3e-80 268.4 0.0 6.3e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.3 GAO86682.1 - 4.8e-51 172.9 0.3 6.1e-51 172.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.1 GAO86683.1 - 4.4e-14 51.9 16.6 9.5e-08 31.9 1.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAO86683.1 - 5e-10 39.1 24.9 0.007 16.6 0.1 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO86683.1 - 5.9e-08 32.5 22.1 0.0087 16.3 4.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO86683.1 - 0.0018 18.3 9.1 0.4 10.8 1.7 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAO86683.1 - 0.029 14.2 13.2 0.055 13.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 GAO86683.1 - 0.063 13.4 10.9 0.13 12.3 4.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 GAO86683.1 - 0.066 13.0 4.9 5.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 GAO86683.1 - 0.19 11.5 6.3 2.4 8.0 4.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 GAO86683.1 - 0.21 11.5 9.0 2.9 7.9 2.3 3.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 GAO86683.1 - 0.24 11.4 3.8 15 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 GAO86683.1 - 0.46 10.3 9.1 3 7.7 3.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 GAO86683.1 - 0.81 9.8 7.6 1.6 8.9 5.3 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 GAO86683.1 - 1.1 9.0 8.8 0.046 13.4 1.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 GAO86683.1 - 4.5 7.4 11.1 2.3 8.3 0.9 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 GAO86683.1 - 8.3 6.0 12.2 3 7.4 1.2 3.2 1 1 2 3 3 3 0 GAGA factor FYDLN_acid PF09538.5 GAO86683.1 - 8.4 7.0 10.4 1.5 9.4 0.9 3.4 3 1 1 4 4 3 0 Protein of unknown function (FYDLN_acid) DUF202 PF02656.10 GAO86684.1 - 0.0065 16.6 3.1 2.2 8.5 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF202) FixQ PF05545.6 GAO86684.1 - 0.015 14.9 0.7 0.015 14.9 0.5 2.7 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Chromate_transp PF02417.10 GAO86684.1 - 0.065 12.8 2.0 0.25 10.9 0.5 2.2 2 0 0 2 2 2 0 Chromate transporter Neur_chan_memb PF02932.11 GAO86684.1 - 0.76 9.6 7.0 2.7 7.8 0.0 3.6 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region Cnd2 PF05786.9 GAO86685.1 - 1.9e-285 949.1 1.2 2.2e-285 948.8 0.8 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4611 PF15387.1 GAO86685.1 - 0.039 14.0 0.6 0.039 14.0 0.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Na_Ca_ex PF01699.19 GAO86686.1 - 1e-48 164.5 36.4 2.7e-24 85.3 8.3 3.5 2 1 1 3 3 3 3 Sodium/calcium exchanger protein DUF3328 PF11807.3 GAO86686.1 - 1.7 8.2 6.6 15 5.1 0.5 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) EF-hand_4 PF12763.2 GAO86687.1 - 1.7e-25 88.7 0.0 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 GAO86687.1 - 1.4e-16 60.2 110.6 2.9e-06 27.2 23.0 6.8 4 1 2 6 6 6 5 Domain of unknown function (DUF1720) WH2 PF02205.15 GAO86687.1 - 3.7e-09 35.8 0.2 8e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 GAO86687.1 - 6.6e-06 26.1 0.2 0.00018 21.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO86687.1 - 0.0073 15.5 0.0 0.067 12.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAO86687.1 - 0.1 12.5 0.4 3.4 7.7 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain RNA_pol_L_2 PF13656.1 GAO86688.1 - 6.2e-25 86.4 0.0 8.9e-25 85.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAO86688.1 - 8.4e-12 44.0 0.0 1.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.10 GAO86689.1 - 2.9e-38 131.8 5.2 1.7e-37 129.3 3.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 GAO86689.1 - 4.4e-07 29.0 4.2 6e-07 28.6 2.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAO86689.1 - 0.00019 20.4 0.0 0.017 14.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO86689.1 - 0.002 17.1 0.6 0.0029 16.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Nucleo_P87 PF07267.6 GAO86690.1 - 0.4 9.3 5.9 0.78 8.3 4.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FYVE PF01363.16 GAO86691.1 - 0.066 13.1 2.7 0.081 12.8 0.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger Tom37_C PF11801.3 GAO86691.1 - 0.99 9.2 7.0 0.17 11.7 2.1 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain CDC27 PF09507.5 GAO86691.1 - 2.1 7.4 14.4 3 6.9 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SNF2_N PF00176.18 GAO86692.1 - 9.1e-68 228.2 0.1 1.5e-67 227.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO86692.1 - 4.4e-12 45.6 0.0 1.3e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 GAO86692.1 - 3.2e-06 26.6 7.7 6.1e-06 25.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO86692.1 - 0.00031 20.7 7.8 0.0007 19.5 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO86692.1 - 0.00073 19.3 8.7 0.0014 18.4 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAO86692.1 - 0.0035 16.9 7.5 0.0071 15.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO86692.1 - 0.013 15.2 8.3 0.023 14.4 5.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 GAO86692.1 - 0.03 13.8 1.5 0.067 12.6 1.0 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C3HC4_4 PF15227.1 GAO86692.1 - 0.089 12.6 6.7 0.17 11.7 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAO86692.1 - 0.15 11.9 3.1 0.34 10.7 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 GAO86692.1 - 0.25 11.1 4.9 0.13 12.0 1.6 2.0 2 0 0 2 2 2 0 RING-type zinc-finger C2 PF00168.25 GAO86693.1 - 1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 GAO86694.1 - 9.4e-35 118.9 0.1 9.4e-35 118.9 0.1 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 GAO86694.1 - 1.5e-12 47.5 0.1 5.8e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 PH domain YTH PF04146.10 GAO86695.1 - 6.8e-57 190.9 0.0 2e-54 183.0 0.0 2.4 1 1 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 GAO86695.1 - 2.5e-06 27.3 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO86695.1 - 2.9e-06 26.7 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86695.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 GAO86695.1 - 0.11 11.4 0.5 0.19 10.7 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 GAO86695.1 - 0.64 7.9 7.1 1.1 7.1 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAO86695.1 - 0.67 8.3 10.3 1 7.7 7.1 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 GAO86695.1 - 5.1 6.2 15.8 8.1 5.6 10.9 1.2 1 0 0 1 1 1 0 SDA1 PI3_PI4_kinase PF00454.22 GAO86697.1 - 7.6e-35 120.4 0.0 4e-34 118.1 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAO86697.1 - 4.7e-24 84.5 0.2 8.8e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 GAO86698.1 - 2.7e-77 259.4 0.0 4.2e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.17 GAO86698.1 - 6.4e-65 219.4 0.0 9e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.12 GAO86698.1 - 1e-36 126.3 0.0 1.6e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAO86698.1 - 2.1e-16 59.7 0.1 4.6e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAO86698.1 - 3.5e-12 45.8 0.0 5.9e-11 41.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAO86698.1 - 1.2e-05 25.1 0.1 3.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAO86698.1 - 0.047 12.4 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 GAO86698.1 - 0.048 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IGR PF09597.5 GAO86699.1 - 1.3e-22 79.4 0.5 1.9e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 GAO86700.1 - 4.9e-65 219.2 0.0 5.9e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86700.1 - 8.6e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO86700.1 - 0.0025 16.8 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kinesin PF00225.18 GAO86701.1 - 9.6e-96 320.3 0.0 1.6e-95 319.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DAGAT PF03982.8 GAO86702.1 - 1.1e-65 221.3 0.0 1.5e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase G-patch PF01585.18 GAO86702.1 - 4.8e-05 23.0 0.4 0.0014 18.3 0.0 3.3 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 GAO86702.1 - 0.064 13.1 0.0 0.064 13.1 0.0 2.8 2 1 0 2 2 2 0 DExH-box splicing factor binding site Med19 PF10278.4 GAO86702.1 - 1.4 8.5 17.6 2.3 7.8 12.2 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 GAO86702.1 - 3.5 6.7 12.6 5.2 6.1 8.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 GAO86702.1 - 3.5 7.3 9.0 5.9 6.6 6.2 1.4 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 GAO86702.1 - 7.6 5.8 10.0 15 4.9 6.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Syja_N PF02383.13 GAO86703.1 - 3.5e-51 173.8 0.0 2.6e-38 131.6 0.0 2.1 1 1 1 2 2 2 2 SacI homology domain Exo_endo_phos PF03372.18 GAO86703.1 - 2.4e-17 63.6 0.1 3.9e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 GAO86703.1 - 0.071 12.5 0.2 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Hid1 PF12722.2 GAO86704.1 - 0.03 12.0 2.6 0.043 11.5 1.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 GAO86704.1 - 2.4 6.6 5.1 3.3 6.2 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med17 PF10156.4 GAO86704.1 - 5 5.2 13.0 7.3 4.7 9.0 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex TPR_11 PF13414.1 GAO86705.1 - 5.4e-08 32.3 5.5 0.008 15.8 0.2 4.3 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 GAO86705.1 - 7.9e-06 26.0 8.2 0.013 16.1 0.2 4.8 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO86705.1 - 1.1e-05 25.2 0.5 0.047 13.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86705.1 - 0.00011 22.7 4.9 0.14 12.8 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO86705.1 - 0.00013 21.6 4.2 0.0026 17.5 0.1 4.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO86705.1 - 0.00064 20.0 4.1 0.06 13.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO86705.1 - 0.0016 17.9 0.1 0.082 12.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO86705.1 - 0.0051 16.5 0.1 0.076 12.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 GAO86705.1 - 0.055 13.7 1.0 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF627 PF04781.7 GAO86705.1 - 0.056 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_12 PF13424.1 GAO86705.1 - 0.31 11.0 5.9 1.5 8.7 0.2 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.15 GAO86706.1 - 1.5e-42 145.6 0.6 3.2e-35 121.4 0.1 2.2 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 GAO86706.1 - 2.3e-08 34.1 4.4 0.022 15.0 0.2 4.1 3 1 0 3 3 3 3 HEAT repeats Cnd1 PF12717.2 GAO86706.1 - 0.00041 20.2 4.1 0.094 12.5 1.5 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAO86706.1 - 0.019 14.9 3.7 8.2 6.8 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat BLVR PF06375.6 GAO86706.1 - 0.026 14.3 2.0 0.099 12.4 0.0 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) API5 PF05918.6 GAO86706.1 - 0.069 11.6 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.1 GAO86706.1 - 0.092 13.2 10.0 40 4.8 0.1 6.2 3 3 3 6 6 6 0 HEAT-like repeat Herpes_UL32 PF06070.6 GAO86707.1 - 0.16 10.3 3.5 0.21 9.9 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF2298 PF10060.4 GAO86708.1 - 0.097 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Aldedh PF00171.17 GAO86709.1 - 3.2e-10 38.9 6.1 5.5e-08 31.5 2.2 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L18e PF00828.14 GAO86710.1 - 1.1e-25 90.4 0.1 1.1e-25 90.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 GAO86711.1 - 6.9e-76 250.0 1.8 8.3e-25 86.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4235 PF14019.1 GAO86711.1 - 0.084 12.7 0.1 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Colicin_V PF02674.11 GAO86711.1 - 1.7 8.5 4.9 6.4 6.6 0.0 3.3 4 0 0 4 4 4 0 Colicin V production protein RRM_1 PF00076.17 GAO86712.1 - 1.3e-11 43.9 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86712.1 - 7.5e-08 32.2 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86712.1 - 3.9e-07 29.7 0.0 5.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO86712.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.26 GAO86713.1 - 3.2e-67 223.4 0.0 1.3e-20 73.4 0.4 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 GAO86713.1 - 3.9e-09 36.5 0.7 2.4e-07 30.7 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO86713.1 - 1.8e-06 26.8 1.0 0.39 10.1 0.0 3.7 3 0 0 3 3 3 3 EF hand CAMSAP_CH PF11971.3 GAO86713.1 - 0.00013 21.5 0.0 0.33 10.6 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.1 GAO86713.1 - 0.0015 18.2 3.6 0.032 14.1 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 GAO86713.1 - 0.37 10.2 2.6 1.3 8.5 0.2 2.9 2 0 0 2 2 2 0 EF hand DDHD PF02862.12 GAO86714.1 - 9.6e-56 189.1 3.4 2.5e-53 181.2 0.0 2.6 2 0 0 2 2 2 2 DDHD domain Lipase_3 PF01764.20 GAO86714.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) PXA PF02194.10 GAO86715.1 - 2.9e-36 124.7 0.1 6.5e-36 123.6 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 GAO86715.1 - 8.9e-27 93.4 0.1 2.4e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal 4HBT PF03061.17 GAO86715.1 - 3.1e-10 40.0 0.2 7.1e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Thioesterase superfamily PX PF00787.19 GAO86715.1 - 1.1e-06 28.4 0.1 6.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 PX domain PC4 PF02229.11 GAO86716.1 - 9.1e-24 82.4 0.1 1.9e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) GDPD PF03009.12 GAO86716.1 - 0.044 13.2 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family MIT PF04212.13 GAO86717.1 - 4.7e-09 36.0 1.0 1.3e-08 34.5 0.2 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AsnA PF03590.10 GAO86717.1 - 0.003 17.0 0.1 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate-ammonia ligase Fungal_trans PF04082.13 GAO86718.1 - 0.00091 18.1 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adeno_PIX PF03955.9 GAO86719.1 - 0.093 13.2 1.9 0.16 12.4 0.2 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Peptidase_M24 PF00557.19 GAO86720.1 - 1.5e-56 191.2 0.5 2.2e-56 190.6 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAO86720.1 - 3.6e-25 87.8 0.0 8.6e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BTB PF00651.26 GAO86721.1 - 0.059 13.3 0.0 0.35 10.8 0.0 2.3 1 1 0 1 1 1 0 BTB/POZ domain Peptidase_M1 PF01433.15 GAO86722.1 - 5.6e-29 101.4 0.0 6.7e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 GAO86723.1 - 4e-46 156.1 0.0 5.4e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Ubiq_cyt_C_chap PF03981.7 GAO86724.1 - 2.7e-39 134.2 0.1 5.4e-39 133.2 0.1 1.4 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.8 GAO86725.1 - 3.8e-80 267.4 0.3 4.4e-80 267.2 0.2 1.0 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 GAO86726.1 - 7e-71 238.4 0.0 8.9e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86726.1 - 3.6e-44 150.8 0.0 4.7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO86726.1 - 6.4e-07 28.6 0.0 1.9e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAO86726.1 - 4.1e-05 22.7 0.1 6.7e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO86726.1 - 0.024 13.9 0.1 0.052 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 GAO86726.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_kinase PF00696.23 GAO86727.1 - 5.4e-40 137.4 0.9 7.4e-40 137.0 0.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 GAO86727.1 - 8.3e-16 57.4 0.1 5e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 PUA domain GPI-anchored PF10342.4 GAO86728.1 - 8.9e-17 61.3 0.1 5.6e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 GAO86728.1 - 1e-07 32.2 3.5 1.6e-07 31.6 2.5 1.2 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.5 GAO86729.1 - 9.5e-25 86.8 3.8 8.2e-23 80.5 2.6 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 GAO86729.1 - 8.7e-06 25.0 0.2 0.0034 16.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.1 GAO86729.1 - 2.9e-05 24.1 1.1 0.00012 22.1 0.5 2.0 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 GAO86729.1 - 3.5e-05 23.7 0.1 6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAO86729.1 - 0.0043 17.3 0.0 0.0065 16.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 GAO86729.1 - 0.0096 15.6 0.1 0.03 14.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 GAO86729.1 - 0.011 15.1 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAO86729.1 - 0.014 14.5 0.3 0.029 13.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 GAO86729.1 - 0.016 15.6 0.7 0.66 10.4 0.5 2.5 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 GAO86729.1 - 0.038 13.5 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 GAO86729.1 - 0.043 13.2 0.1 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 GAO86729.1 - 0.048 13.8 1.5 0.27 11.4 1.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 GAO86729.1 - 0.062 12.4 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 GAO86729.1 - 0.065 13.3 0.1 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 GAO86729.1 - 0.087 12.2 0.8 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 GAO86729.1 - 0.092 12.3 0.3 0.36 10.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain adh_short PF00106.20 GAO86730.1 - 3.4e-19 69.3 0.2 6.3e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO86730.1 - 1.4e-09 37.9 0.1 2.6e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO86730.1 - 0.00027 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO86730.1 - 0.00072 18.5 0.1 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAO86730.1 - 0.0027 16.4 0.2 0.0052 15.5 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 GAO86730.1 - 0.024 14.3 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO86730.1 - 0.06 13.3 0.6 0.29 11.1 0.4 2.1 1 1 0 1 1 1 0 NADH(P)-binding PALP PF00291.20 GAO86731.1 - 8.6e-59 199.2 0.4 1.1e-58 198.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 GAO86731.1 - 2.4e-06 27.2 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 CBS domain Na_Ca_ex PF01699.19 GAO86732.1 - 1e-22 80.2 20.3 2.1e-16 59.7 1.9 2.5 1 1 1 2 2 2 2 Sodium/calcium exchanger protein Cyclin PF08613.6 GAO86735.1 - 4.5e-37 127.7 0.0 5.8e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAO86735.1 - 0.00066 19.2 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank PF00023.25 GAO86736.1 - 7.5e-38 126.4 5.6 1.6e-10 40.2 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 GAO86736.1 - 2.4e-37 127.9 8.5 2.4e-37 127.9 5.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 GAO86736.1 - 5.2e-37 126.0 0.0 2e-17 63.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO86736.1 - 1.3e-29 101.4 6.5 4.9e-10 39.3 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO86736.1 - 4.2e-26 90.8 11.6 6.7e-07 29.6 0.0 4.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86736.1 - 1.1e-25 87.1 4.1 1.5e-08 34.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat K_oxygenase PF13434.1 GAO86737.1 - 3.1e-109 365.0 0.0 3.8e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAO86737.1 - 5.2e-10 39.7 0.0 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO86737.1 - 4.7e-06 26.6 0.0 0.0014 18.5 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO86737.1 - 5.4e-06 26.2 0.0 4.2e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF4147 PF13660.1 GAO86737.1 - 0.021 13.9 0.0 3.1 6.8 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4147) Pkinase PF00069.20 GAO86738.1 - 1.1e-42 146.0 0.0 2e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86738.1 - 1.2e-24 86.7 0.0 2.9e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO86738.1 - 0.092 12.4 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAO86738.1 - 0.66 8.7 0.1 0.95 8.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase OB_NTP_bind PF07717.11 GAO86739.1 - 2.7e-30 104.5 0.0 7.4e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAO86739.1 - 7.3e-25 86.9 3.3 9.8e-25 86.5 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAO86739.1 - 3.2e-12 46.1 0.0 7.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO86739.1 - 6.6e-06 25.7 0.2 2.5e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO86739.1 - 4.9e-05 23.4 0.1 0.0003 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAO86739.1 - 0.00018 20.5 0.0 0.00038 19.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PWI PF01480.12 GAO86739.1 - 0.0072 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 PWI domain Sigma54_activ_2 PF14532.1 GAO86739.1 - 0.0072 16.3 0.0 0.023 14.7 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain SRP54 PF00448.17 GAO86739.1 - 0.015 14.7 0.1 0.044 13.2 0.0 1.9 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 GAO86739.1 - 0.026 14.2 0.2 0.21 11.3 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 GAO86739.1 - 0.075 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAO86739.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.7 1 1 1 3 3 1 0 AAA domain ABC_tran PF00005.22 GAO86739.1 - 0.18 12.0 1.1 0.79 10.0 0.1 2.6 1 1 1 2 2 2 0 ABC transporter Vault PF01505.13 GAO86739.1 - 0.5 10.4 2.8 3.9 7.5 0.5 2.8 2 0 0 2 2 2 0 Major Vault Protein repeat Cyt-b5 PF00173.23 GAO86740.1 - 1.1e-21 76.4 0.1 1.2e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 GAO86740.1 - 0.045 13.6 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain V-ATPase_H_C PF11698.3 GAO86740.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Mcp5_PH PF12814.2 GAO86741.1 - 8.5e-49 164.5 0.2 1.7e-48 163.5 0.0 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 GAO86741.1 - 0.0024 17.6 16.2 0.0081 15.9 6.1 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein GAS PF13851.1 GAO86741.1 - 0.059 12.5 9.8 0.14 11.3 6.8 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 GAO86741.1 - 0.7 8.8 10.0 1.1 8.2 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Fez1 PF06818.10 GAO86741.1 - 0.83 9.6 15.3 1.5 8.8 10.6 1.3 1 0 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.4 GAO86741.1 - 0.84 9.4 16.7 1.9 8.3 11.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 GAO86741.1 - 2.2 8.1 18.8 2.8 7.7 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 GAO86741.1 - 6.9 6.5 19.5 0.96 9.3 2.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HAD_2 PF13419.1 GAO86742.1 - 1.5e-26 93.6 0.0 3.8e-26 92.3 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO86742.1 - 1.2e-05 25.8 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GST_C_2 PF13410.1 GAO86742.1 - 2.6e-05 24.0 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hydrolase_like PF13242.1 GAO86742.1 - 0.00063 19.4 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like YcaO PF02624.11 GAO86742.1 - 0.019 14.5 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 YcaO-like family GST_C_3 PF14497.1 GAO86742.1 - 0.094 13.2 0.0 0.36 11.3 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1940 PF09155.5 GAO86742.1 - 0.13 12.1 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) AMP-binding PF00501.23 GAO86743.1 - 1.5e-79 267.3 0.0 1.8e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ras PF00071.17 GAO86743.1 - 5.9e-50 168.8 0.1 1.9e-49 167.1 0.1 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAO86743.1 - 1.9e-14 54.2 0.2 1.5e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AMP-binding_C PF13193.1 GAO86743.1 - 1.7e-11 44.9 0.0 4.4e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_25 PF13481.1 GAO86743.1 - 0.0064 15.9 0.0 0.68 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 GAO86743.1 - 0.0099 15.1 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAO86743.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SHMT PF00464.14 GAO86745.1 - 8.7e-195 646.7 0.0 1e-194 646.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MOSC PF03473.12 GAO86746.1 - 4.2e-17 61.8 0.0 7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 GAO86746.1 - 7.3e-16 57.9 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3868 PF12984.2 GAO86747.1 - 0.013 15.0 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Mg_trans_NIPA PF05653.9 GAO86748.1 - 5.8e-93 311.1 23.1 8.7e-93 310.5 16.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA CinA PF02464.12 GAO86748.1 - 5.4e-32 110.3 0.2 1.5e-31 108.9 0.1 1.8 1 0 0 1 1 1 1 Competence-damaged protein Patatin PF01734.17 GAO86748.1 - 5.5e-28 98.2 0.0 1.6e-27 96.8 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase EmrE PF13536.1 GAO86748.1 - 3.2e-06 27.2 5.8 3.2e-06 27.2 4.0 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAO86748.1 - 5e-05 23.3 7.7 5e-05 23.3 5.3 2.6 2 0 0 2 2 2 1 EamA-like transporter family BRCT PF00533.21 GAO86749.1 - 0.00016 21.7 0.0 0.0004 20.4 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAO86749.1 - 0.0014 18.4 2.4 0.0031 17.3 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain Trypan_PARP PF05887.6 GAO86749.1 - 0.021 14.6 7.5 0.048 13.4 5.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) eIF-3c_N PF05470.7 GAO86749.1 - 0.12 10.4 0.1 0.14 10.2 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus KilA-N PF04383.8 GAO86750.1 - 0.00036 20.1 0.0 0.0043 16.6 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain DUF1168 PF06658.7 GAO86750.1 - 0.12 11.9 0.4 0.24 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Sugar_tr PF00083.19 GAO86751.1 - 3.8e-104 348.7 34.8 4.4e-104 348.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86751.1 - 7.1e-28 97.3 40.1 5.5e-27 94.4 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 GAO86751.1 - 1.9 8.2 8.5 0.089 12.4 1.2 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain p450 PF00067.17 GAO86752.1 - 3.5e-58 197.2 0.0 5.3e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_29 PF13551.1 GAO86752.1 - 0.0027 17.8 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 GAO86752.1 - 0.0045 16.6 0.0 0.0093 15.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain FAD_binding_1 PF00667.15 GAO86753.1 - 3.1e-48 164.1 0.0 4.5e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAO86753.1 - 6.3e-26 91.0 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAO86753.1 - 1.1e-21 77.4 0.1 4.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Picorna_P3A PF06363.6 GAO86753.1 - 0.13 12.2 0.2 0.49 10.4 0.1 2.0 2 0 0 2 2 2 0 Picornaviridae P3A protein HA2 PF04408.18 GAO86754.1 - 9.5e-19 67.3 0.1 2.6e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAO86754.1 - 2.3e-12 46.5 0.2 5.3e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO86754.1 - 1.4e-11 44.1 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO86754.1 - 4.1e-07 30.2 0.0 1.9e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 GAO86754.1 - 2e-05 24.3 0.0 5.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RuvA_C PF07499.8 GAO86754.1 - 0.046 13.8 0.3 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF3554 PF12074.3 GAO86755.1 - 7.1e-115 384.0 4.1 1.7e-114 382.8 0.4 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 GAO86755.1 - 4.7e-58 195.1 10.0 4.7e-58 195.1 6.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L19e HEAT PF02985.17 GAO86755.1 - 2.6e-39 129.7 24.5 0.015 15.2 0.0 20.0 21 0 0 21 21 18 10 HEAT repeat HEAT_2 PF13646.1 GAO86755.1 - 7.3e-39 131.9 47.1 2.4e-09 37.3 0.0 16.6 9 3 9 18 18 17 13 HEAT repeats HEAT_EZ PF13513.1 GAO86755.1 - 1.3e-31 108.2 56.0 3.8e-05 24.0 0.1 23.6 18 6 10 29 29 29 9 HEAT-like repeat Cnd1 PF12717.2 GAO86755.1 - 8e-15 55.1 1.2 0.0011 18.9 0.1 7.6 5 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAO86755.1 - 1.2e-10 41.6 0.0 2.5 8.5 0.0 8.1 5 3 2 7 7 7 2 Vacuolar 14 Fab1-binding region ParcG PF10274.4 GAO86755.1 - 2.8e-09 37.1 4.2 0.15 11.9 0.0 7.3 6 2 2 8 8 8 2 Parkin co-regulated protein Ipi1_N PF12333.3 GAO86755.1 - 3.7e-05 23.6 4.6 0.23 11.4 0.0 6.6 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.2 GAO86755.1 - 0.0053 16.6 2.5 1 9.3 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_N PF03224.9 GAO86755.1 - 0.0062 15.7 8.2 4.5 6.3 1.5 4.5 4 0 0 4 4 4 2 V-ATPase subunit H Rifin_STEVOR PF02009.11 GAO86756.1 - 0.00065 19.4 0.0 0.00092 18.9 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 GAO86756.1 - 0.0028 17.3 0.5 0.012 15.2 0.3 2.1 1 1 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.15 GAO86756.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 GAO86756.1 - 0.062 12.8 0.5 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 GAO86756.1 - 0.26 10.6 2.0 0.53 9.6 1.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MCPVI PF02993.9 GAO86756.1 - 6.3 6.8 7.6 0.64 10.1 0.8 2.3 1 1 1 2 2 2 0 Minor capsid protein VI TIP39 PF14980.1 GAO86757.1 - 0.72 9.5 4.0 5.3 6.7 0.1 3.1 3 0 0 3 3 3 0 TIP39 peptide Zn_clus PF00172.13 GAO86758.1 - 1.3e-09 37.7 14.3 1.3e-09 37.7 9.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 GAO86758.1 - 0.1 12.1 4.8 0.24 10.9 3.3 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 GAO86759.1 - 4.1e-25 88.6 0.2 2.7e-24 85.9 0.1 2.0 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO86759.1 - 1.6e-09 37.7 0.0 5.3e-08 32.7 0.0 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAO86759.1 - 0.0014 18.1 0.1 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO86759.1 - 0.0081 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO86759.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.9 2 1 0 2 2 2 0 NADH(P)-binding Adenylate_cycl PF01295.13 GAO86760.1 - 0.12 10.6 2.2 0.19 9.9 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I V_ATPase_I PF01496.14 GAO86760.1 - 7.4 4.2 7.0 54 1.4 4.8 2.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 GAO86761.1 - 1.7e-39 135.6 1.0 3.8e-38 131.1 0.7 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 GAO86762.1 - 2.2e-216 718.0 4.8 2.2e-216 718.0 3.3 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DUF3824 PF12868.2 GAO86763.1 - 5.6e-49 166.5 34.5 5.6e-49 166.5 23.9 8.5 5 4 5 10 10 10 2 Domain of unknwon function (DUF3824) CbtA PF09490.5 GAO86763.1 - 0.43 9.8 2.4 0.51 9.6 0.7 1.7 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) NicO PF03824.11 GAO86763.1 - 0.87 8.8 6.1 1.7 7.8 4.3 1.5 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2613 PF11021.3 GAO86763.1 - 1.9 8.2 6.3 4.2 7.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) DDE_1 PF03184.14 GAO86764.1 - 3.3e-31 108.1 0.2 3.3e-30 104.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAO86764.1 - 3.4e-08 33.1 1.3 6.3e-08 32.3 0.0 2.2 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAO86764.1 - 0.00016 21.1 0.1 0.00033 20.1 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 GAO86764.1 - 4.3 7.4 9.2 3.1 7.8 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain Ank_2 PF12796.2 GAO86765.1 - 7.7e-82 269.7 0.6 4e-13 49.5 0.0 7.9 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86765.1 - 2.5e-69 225.8 15.4 4.7e-05 22.9 0.0 15.5 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 GAO86765.1 - 4.1e-62 205.5 4.4 4.4e-10 39.8 0.0 10.4 7 3 3 10 10 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO86765.1 - 2.3e-54 180.2 17.6 3.2e-06 27.1 0.0 12.0 4 2 9 13 13 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO86765.1 - 1.5e-44 145.5 0.8 0.00019 21.3 0.0 15.1 14 0 0 14 14 14 9 Ankyrin repeat Hexokinase_2 PF03727.11 GAO86765.1 - 1.1e-22 80.5 0.0 9.7e-20 70.7 0.0 2.6 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 GAO86765.1 - 5e-19 68.4 0.0 1.8e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 Hexokinase NACHT PF05729.7 GAO86765.1 - 1.5e-13 50.7 1.0 9.5e-06 25.3 0.0 3.9 3 2 0 3 3 3 2 NACHT domain T5orf172 PF10544.4 GAO86765.1 - 6e-13 49.0 0.0 2.2e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 T5orf172 domain AAA_16 PF13191.1 GAO86765.1 - 3.2e-10 40.3 0.7 1.5e-06 28.3 0.0 4.5 3 1 0 3 3 3 1 AAA ATPase domain MUG113 PF13455.1 GAO86765.1 - 7.8e-10 39.0 0.1 2.4e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 AAA_22 PF13401.1 GAO86765.1 - 1.6e-08 34.7 0.3 0.0027 17.8 0.0 3.9 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 GAO86765.1 - 1.4e-05 24.8 1.5 0.19 11.4 0.0 3.5 3 0 0 3 3 3 2 Archaeal ATPase RNA_helicase PF00910.17 GAO86765.1 - 0.00013 22.1 0.1 0.0051 16.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.1 GAO86765.1 - 0.0022 18.3 0.0 0.01 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAO86765.1 - 0.033 13.6 0.0 0.49 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_17 PF13207.1 GAO86765.1 - 0.047 14.5 0.2 0.34 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAO86765.1 - 0.23 11.1 0.0 7.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2291 PF10054.4 GAO86765.1 - 0.34 10.1 0.0 0.65 9.2 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) SE PF08491.5 GAO86767.1 - 2.3e-92 308.7 0.0 2.9e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 GAO86767.1 - 1.3e-09 37.4 0.2 8.9e-07 28.1 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO86767.1 - 7.3e-08 31.8 0.0 2.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 GAO86767.1 - 1.7e-07 30.4 0.0 2.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO86767.1 - 6.8e-06 24.9 0.0 0.005 15.5 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 GAO86767.1 - 1.1e-05 24.5 2.8 3.6e-05 22.8 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAO86767.1 - 1.4e-05 24.4 0.9 2e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO86767.1 - 6.7e-05 22.8 0.9 0.0002 21.2 0.6 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO86767.1 - 0.00083 17.9 0.3 0.0033 15.9 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAO86767.1 - 0.0023 17.0 0.1 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAO86767.1 - 0.0078 15.1 0.2 0.12 11.2 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GMC_oxred_N PF00732.14 GAO86767.1 - 0.01 15.0 0.2 0.5 9.4 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.22 GAO86767.1 - 0.01 16.1 1.6 0.018 15.4 0.6 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO86767.1 - 0.018 14.8 0.7 0.028 14.3 0.5 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spherulin4 PF12138.3 GAO86769.1 - 2.4e-40 138.5 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 MU117 PF15474.1 GAO86769.1 - 4.5e-16 59.1 12.7 1.2e-15 57.7 8.8 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene family Lipase_GDSL_2 PF13472.1 GAO86769.1 - 3.1e-10 40.4 0.2 8.1e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.16 GAO86769.1 - 0.00037 20.5 0.3 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain ChitinaseA_N PF08329.5 GAO86769.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Chitinase A, N-terminal domain Sugar_tr PF00083.19 GAO86770.1 - 6.2e-80 268.9 25.9 7.1e-80 268.7 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86770.1 - 1.2e-27 96.6 20.4 8.2e-26 90.5 15.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L44 PF00935.14 GAO86771.1 - 1.3e-33 114.8 12.3 2.4e-33 113.9 8.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 DUF1436 PF07262.6 GAO86771.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) ubiquitin PF00240.18 GAO86772.1 - 2.3e-24 84.5 0.0 2.6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAO86772.1 - 9e-16 57.3 0.1 9.9e-16 57.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAO86772.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 GAO86773.1 - 9.6e-33 112.8 0.1 1.5e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FAM220 PF15487.1 GAO86773.1 - 3.1 7.0 6.1 3.7 6.8 3.6 1.5 1 1 0 1 1 1 0 FAM220 family DUF4407 PF14362.1 GAO86774.1 - 1.5 7.6 13.5 2 7.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBCA PF02970.11 GAO86775.1 - 1.5e-27 95.4 12.3 1.8e-27 95.2 8.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Dynamin_M PF01031.15 GAO86775.1 - 0.014 14.2 2.9 0.028 13.2 2.0 1.6 1 1 0 1 1 1 0 Dynamin central region PspA_IM30 PF04012.7 GAO86775.1 - 0.04 13.2 14.1 0.16 11.3 1.9 2.3 1 1 1 2 2 2 0 PspA/IM30 family TAP42 PF04177.7 GAO86775.1 - 0.082 11.8 7.0 0.091 11.6 4.9 1.1 1 0 0 1 1 1 0 TAP42-like family DUF444 PF04285.7 GAO86775.1 - 0.12 11.0 2.6 0.14 10.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF4559 PF15112.1 GAO86775.1 - 0.4 9.8 4.5 0.44 9.6 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) LMBR1 PF04791.11 GAO86775.1 - 0.47 8.9 2.7 0.44 9.0 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HrpA_pilin PF09589.5 GAO86775.1 - 0.5 10.7 2.8 0.89 9.9 1.9 1.5 1 1 0 1 1 1 0 HrpA pilus formation protein DUF2570 PF10828.3 GAO86775.1 - 0.56 9.8 7.6 0.96 9.0 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) V_ATPase_I PF01496.14 GAO86775.1 - 0.63 7.8 7.9 0.64 7.8 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 GAO86775.1 - 0.68 9.0 7.4 0.8 8.8 5.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.4 GAO86775.1 - 0.78 9.7 8.3 0.88 9.5 5.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Spc7 PF08317.6 GAO86775.1 - 0.8 8.3 11.2 0.91 8.1 7.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.6 GAO86775.1 - 0.92 8.6 5.6 1.1 8.4 3.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 GAO86775.1 - 0.98 8.9 12.0 1.3 8.5 8.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 GAO86775.1 - 1.9 7.4 8.7 2.1 7.2 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyD PF00529.15 GAO86775.1 - 2.6 7.2 12.5 3 7.0 8.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CENP-Q PF13094.1 GAO86775.1 - 3.8 7.5 16.3 11 5.9 11.3 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 GAO86775.1 - 9.6 5.8 13.8 24 4.5 9.6 1.7 1 1 0 1 1 1 0 Mnd1 family THOC7 PF05615.8 GAO86776.1 - 4.3e-39 133.9 10.6 4.3e-39 133.9 7.4 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 GAO86776.1 - 0.0069 16.4 11.7 0.0092 16.0 3.7 2.4 1 1 2 3 3 3 1 Zinc finger-containing protein SSFA2_C PF14723.1 GAO86776.1 - 0.0096 15.6 3.9 0.0096 15.6 2.7 1.7 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus DUF4600 PF15372.1 GAO86776.1 - 0.11 12.7 9.7 0.22 11.7 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) CHASE3 PF05227.8 GAO86776.1 - 0.2 11.3 15.1 0.099 12.3 4.7 2.6 1 1 1 2 2 2 0 CHASE3 domain FUSC PF04632.7 GAO86776.1 - 0.24 9.7 5.4 0.26 9.6 3.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_23 PF13476.1 GAO86776.1 - 0.33 11.2 5.7 0.54 10.5 3.9 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 GAO86776.1 - 0.7 7.6 4.2 0.93 7.2 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 GAO86776.1 - 2.8 6.2 7.1 4.7 5.5 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 GAO86776.1 - 8.4 6.3 8.8 1.2 9.0 2.7 2.1 2 0 0 2 2 2 0 FlxA-like protein DBD_Tnp_Mut PF03108.10 GAO86777.1 - 2.5e-12 46.1 0.5 4.4e-12 45.4 0.3 1.3 1 0 0 1 1 1 1 MuDR family transposase MFS_1 PF07690.11 GAO86778.1 - 3.9e-48 163.9 48.3 3.7e-44 150.8 35.1 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO86778.1 - 5.2e-17 61.2 24.7 6.7e-17 60.9 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO86778.1 - 5.5e-10 38.4 13.6 5.5e-10 38.4 9.4 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 GAO86778.1 - 7.5e-06 24.6 37.3 2.1e-05 23.1 2.5 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein PgaD PF13994.1 GAO86778.1 - 0.027 13.9 0.3 0.19 11.2 0.3 2.3 2 0 0 2 2 2 0 PgaD-like protein Fungal_trans PF04082.13 GAO86779.1 - 7.7e-32 110.1 0.5 1.3e-31 109.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86779.1 - 0.0002 21.2 4.5 0.00032 20.5 3.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.15 GAO86780.1 - 3.3e-47 161.1 0.0 6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_Gly3P_dh_N PF01210.18 GAO86780.1 - 6.2e-42 142.9 0.0 1.2e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 GAO86780.1 - 3.5e-39 133.8 0.0 5.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Malic_M PF03949.10 GAO86781.1 - 1.1e-85 287.2 0.0 1.5e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAO86781.1 - 1.7e-63 213.4 0.0 3.5e-63 212.4 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.1 GAO86782.1 - 2.4e-06 27.5 0.3 2.4e-06 27.5 0.2 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 GAO86782.1 - 0.015 15.1 3.6 0.03 14.1 0.6 2.9 3 0 0 3 3 3 0 Tricorn protease C1 domain Jnk-SapK_ap_N PF09744.4 GAO86782.1 - 0.016 15.1 2.4 0.044 13.7 1.6 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FCD PF07729.7 GAO86782.1 - 0.088 13.1 0.2 0.088 13.1 0.1 3.2 2 1 1 3 3 3 0 FCD domain Val_tRNA-synt_C PF10458.4 GAO86782.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2188 PF09954.4 GAO86782.1 - 0.1 12.5 0.6 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2018 PF09442.5 GAO86782.1 - 0.12 13.0 0.1 0.64 10.6 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) YtxH PF12732.2 GAO86782.1 - 6.5 7.2 11.6 4.5e+02 1.2 7.2 4.0 2 1 0 2 2 2 0 YtxH-like protein DnaJ PF00226.26 GAO86783.1 - 5.5e-25 86.8 0.9 8.4e-25 86.2 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAO86783.1 - 4.4e-17 61.8 12.7 7.1e-17 61.2 8.8 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 GAO86783.1 - 5.9e-11 42.1 0.0 2.5e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain HypA PF01155.14 GAO86783.1 - 0.17 11.5 7.0 0.27 10.9 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 GAO86783.1 - 0.28 11.4 9.3 1.3 9.3 0.1 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar DUF11 PF01345.13 GAO86784.1 - 0.044 13.8 0.1 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF11 S4 PF01479.20 GAO86785.1 - 1.4e-12 46.7 0.0 3.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Occludin_ELL PF07303.8 GAO86785.1 - 0.0005 20.7 0.3 0.0014 19.3 0.2 1.7 1 0 0 1 1 1 1 Occludin homology domain COG2 PF06148.6 GAO86785.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.11 GAO86787.1 - 6.8e-36 123.7 27.7 6.8e-35 120.4 17.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 GAO86787.1 - 0.1 12.9 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) OMPdecase PF00215.19 GAO86788.1 - 6.9e-79 264.4 0.0 8e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 GAO86789.1 - 4.1e-26 91.0 2.0 4.9e-26 90.8 1.4 1.0 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 GAO86790.1 - 1.2e-21 77.1 12.3 1.2e-21 77.1 8.5 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAO86790.1 - 0.0097 15.9 1.9 0.0097 15.9 1.3 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WD40 PF00400.27 GAO86791.1 - 1.8e-49 163.8 31.3 3.4e-09 36.2 1.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAO86791.1 - 0.00017 21.3 0.4 0.033 13.8 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 GAO86791.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.4 GAO86792.1 - 0.002 18.1 4.1 0.0026 17.7 2.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 ICMT PF04140.9 GAO86794.1 - 7e-28 96.6 0.5 1.5e-27 95.5 0.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAO86794.1 - 1.3e-14 54.1 2.0 1.3e-14 54.1 1.4 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAO86794.1 - 0.00011 21.5 0.8 0.00013 21.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SNARE_assoc PF09335.6 GAO86794.1 - 0.13 12.5 0.1 0.13 12.5 0.0 2.9 3 1 0 3 3 3 0 SNARE associated Golgi protein Mac PF12464.3 GAO86795.1 - 4.6e-16 58.5 0.1 8.2e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAO86795.1 - 1.2e-15 56.2 6.4 3.4e-10 38.9 1.6 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAO86795.1 - 9.3e-11 41.1 7.9 6.3e-08 32.0 1.0 2.9 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF3517 PF12030.3 GAO86796.1 - 1.7e-184 612.0 0.2 3.7e-184 610.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 GAO86796.1 - 1.3e-46 158.9 0.8 2.4e-46 158.0 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO86796.1 - 4.9e-18 65.6 0.6 1.1e-17 64.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TFIIE_alpha PF02002.12 GAO86797.1 - 2.1e-17 62.5 0.0 5.6e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 GAO86797.1 - 0.025 14.5 0.2 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 GAO86797.1 - 0.048 12.9 2.2 1.4 8.3 1.5 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_L37ae PF01780.14 GAO86797.1 - 0.07 13.0 0.6 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family PseudoU_synth_1 PF01416.15 GAO86798.1 - 8.4e-21 74.3 0.1 6.6e-10 39.3 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF721 PF05258.7 GAO86798.1 - 0.099 12.8 0.0 8.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF721) Anillin PF08174.6 GAO86799.1 - 6.1e-34 117.0 0.2 2.3e-33 115.1 0.1 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 GAO86799.1 - 6.7e-09 35.8 0.0 2.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 PH domain DEAD PF00270.24 GAO86800.1 - 1.8e-33 115.4 0.2 3.6e-33 114.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO86800.1 - 1.7e-14 53.4 0.0 9.1e-14 51.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO86800.1 - 0.00059 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAO86800.1 - 0.0058 15.4 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 GAO86800.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain COesterase PF00135.23 GAO86801.1 - 1.5e-76 258.2 0.0 1.7e-76 258.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO86801.1 - 7.8e-06 25.6 0.1 8.7e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO86801.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SET PF00856.23 GAO86802.1 - 7.7e-10 39.3 0.1 2.1e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 SET domain HypA PF01155.14 GAO86802.1 - 0.77 9.4 3.8 3.3 7.4 2.6 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_L14 PF00238.14 GAO86803.1 - 2e-46 156.7 2.2 2.2e-46 156.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 GAO86804.1 - 1e-10 41.1 1.5 1e-10 41.1 1.0 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 GAO86804.1 - 0.006 16.5 6.5 1.1 9.2 0.0 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 GAO86804.1 - 0.035 13.9 10.0 0.96 9.3 1.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 GAO86804.1 - 0.17 11.6 11.0 2.1 8.1 0.2 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 GAO86804.1 - 0.74 9.0 11.5 0.94 8.7 0.4 3.6 3 1 1 4 4 4 0 zinc-ribbon domain FYVE PF01363.16 GAO86804.1 - 1.3 9.0 6.8 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_2 PF13240.1 GAO86804.1 - 5.2 6.6 12.7 1.1 8.7 0.4 3.5 3 1 0 3 3 3 0 zinc-ribbon domain CytoC_RC PF02276.13 GAO86804.1 - 5.3 6.0 7.6 14 4.6 5.3 1.7 1 1 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Rotamase PF00639.16 GAO86805.1 - 9.3e-22 77.5 0.1 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 GAO86805.1 - 9.6e-14 51.6 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 GAO86805.1 - 3e-10 39.7 1.1 3e-10 39.7 0.8 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 GAO86805.1 - 5.2e-06 27.0 0.0 1.6e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain MAM PF00629.18 GAO86805.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 MAM domain TACC PF05010.9 GAO86806.1 - 0.025 14.3 9.6 0.054 13.2 6.7 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF948 PF06103.6 GAO86806.1 - 0.11 12.4 0.6 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 GAO86806.1 - 1.9 8.1 12.8 1.7 8.2 5.1 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 RRM_5 PF13893.1 GAO86807.1 - 3.1e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO86807.1 - 4e-05 23.1 0.0 7.6e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86807.1 - 0.00087 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.14 GAO86808.1 - 1e-57 194.8 0.0 1.1e-46 158.8 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAO86808.1 - 6.5e-10 38.8 0.0 1e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 GAO86808.1 - 2.8e-05 23.6 0.0 5.8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 GAO86808.1 - 0.00042 19.7 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 GAO86808.1 - 0.00069 18.9 0.2 0.0046 16.2 0.0 2.0 2 0 0 2 2 2 1 Putative amidotransferase ACPS PF01648.15 GAO86809.1 - 3.9e-12 46.0 0.0 7.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 GAO86810.1 - 1.9e-34 117.9 0.0 3e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.23 GAO86811.1 - 2.5e-44 147.1 14.6 1.2e-08 34.1 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAO86811.1 - 1.6e-37 124.3 12.7 2.4e-06 27.0 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAO86811.1 - 3.4e-37 125.9 16.1 4.4e-11 42.2 1.1 6.5 3 1 4 7 7 7 7 TPR repeat TPR_8 PF13181.1 GAO86811.1 - 8e-29 97.2 1.8 0.0023 17.5 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86811.1 - 8e-23 80.5 3.9 1.6e-08 35.0 0.1 6.3 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86811.1 - 2.3e-22 78.7 9.2 0.00013 21.8 0.2 6.4 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAO86811.1 - 1.1e-19 69.1 2.8 0.059 14.0 0.0 7.5 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAO86811.1 - 1.1e-16 60.9 6.6 3.8e-05 23.9 0.6 6.2 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAO86811.1 - 1.2e-13 50.1 10.9 0.18 12.1 0.0 8.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAO86811.1 - 1.8e-11 42.9 5.5 0.0047 16.6 0.0 7.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO86811.1 - 8.7e-09 35.2 7.0 0.76 10.3 0.3 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 GAO86811.1 - 1.4e-05 25.1 12.4 0.011 15.8 0.4 3.7 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAO86811.1 - 0.00061 19.5 2.9 3.3 7.6 0.2 4.7 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAO86811.1 - 0.0015 17.6 2.4 1.5 7.8 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 GAO86811.1 - 0.019 14.9 2.4 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 GAO86811.1 - 0.023 14.5 1.5 0.66 9.9 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain FAT PF02259.18 GAO86811.1 - 0.026 13.5 1.9 1 8.2 0.2 3.5 2 1 1 3 3 3 0 FAT domain DUF2225 PF09986.4 GAO86811.1 - 6.6 6.1 7.0 2.4 7.5 0.1 3.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF788 PF05620.6 GAO86812.1 - 7e-48 162.6 0.0 7.9e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) RINGv PF12906.2 GAO86814.1 - 6e-15 55.0 8.2 1e-14 54.3 5.7 1.4 1 0 0 1 1 1 1 RING-variant domain S1FA PF04689.8 GAO86814.1 - 0.49 10.2 0.6 1.4 8.8 0.4 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA zf-C3HC4_3 PF13920.1 GAO86814.1 - 0.84 9.3 4.9 1.4 8.6 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO86814.1 - 3.9 7.3 8.3 7 6.5 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain HeLo PF14479.1 GAO86815.1 - 0.003 17.3 0.5 0.022 14.4 0.3 2.1 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 GAO86815.1 - 0.021 13.9 0.0 0.06 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_S64 PF08192.6 GAO86815.1 - 0.11 10.8 0.0 0.22 9.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S64 DUF2630 PF10944.3 GAO86815.1 - 2.2 8.4 5.0 12 6.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2630) ACC_central PF08326.7 GAO86816.1 - 2.7e-268 891.9 0.0 3.9e-268 891.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAO86816.1 - 5.7e-182 605.4 0.0 8.3e-182 604.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAO86816.1 - 9.1e-52 175.4 0.0 1.9e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAO86816.1 - 4.9e-24 84.5 0.1 9.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAO86816.1 - 1.8e-22 79.3 0.0 1e-19 70.5 0.0 3.3 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAO86816.1 - 1.4e-16 59.8 0.1 3.6e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAO86816.1 - 4.7e-10 39.5 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAO86816.1 - 3e-08 32.8 0.0 0.02 13.6 0.0 3.2 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAO86816.1 - 7.8e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAO86816.1 - 0.0042 16.9 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAO86816.1 - 0.017 14.7 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like RimK PF08443.6 GAO86816.1 - 0.1 12.0 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain NUDE_C PF04880.8 GAO86817.1 - 1.6e-38 132.6 8.9 1.6e-38 132.6 6.2 4.7 3 2 1 4 4 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 GAO86817.1 - 0.00018 21.7 8.0 0.00018 21.7 5.5 4.2 2 1 1 3 3 3 1 Protein of unknown function (DUF904) IncA PF04156.9 GAO86817.1 - 0.003 17.1 31.7 0.024 14.2 10.4 2.6 2 1 1 3 3 3 2 IncA protein WEMBL PF05701.6 GAO86817.1 - 0.0068 14.9 26.0 0.01 14.3 18.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ADIP PF11559.3 GAO86817.1 - 0.43 10.4 34.5 0.18 11.7 3.7 3.6 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.8 GAO86817.1 - 0.66 9.4 8.1 1.2 8.6 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 GAO86817.1 - 0.69 9.7 32.3 0.61 9.9 8.2 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 GAO86817.1 - 0.85 9.4 33.8 1.9 8.3 14.7 3.3 2 1 1 3 3 3 0 Tropomyosin like Filament PF00038.16 GAO86817.1 - 1.1 8.6 28.3 8.6 5.7 19.5 2.1 1 1 0 1 1 1 0 Intermediate filament protein Peptidase_S46 PF10459.4 GAO86817.1 - 1.1 7.6 10.9 1.5 7.1 7.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Tho2 PF11262.3 GAO86817.1 - 5.6 5.9 15.1 2.9 6.8 3.0 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RTBV_P46 PF06216.6 GAO86817.1 - 5.8 5.6 13.2 4.8 5.9 1.3 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein V_ATPase_I PF01496.14 GAO86817.1 - 9.9 3.8 20.0 12 3.5 9.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Isochorismatase PF00857.15 GAO86818.1 - 7.2e-44 149.7 0.0 1.9e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 GAO86818.1 - 2e-06 28.2 0.0 4.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 GAO86818.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 GAO86819.1 - 3.6e-42 143.3 0.0 4.2e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAO86819.1 - 0.00032 20.4 0.0 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 Sybindin-like family Gram_pos_anchor PF00746.16 GAO86819.1 - 0.0024 17.5 0.4 0.0074 16.0 0.2 1.9 2 0 0 2 2 2 1 Gram positive anchor Chorion_2 PF03964.10 GAO86819.1 - 0.026 15.0 0.4 0.038 14.5 0.3 1.4 1 0 0 1 1 1 0 Chorion family 2 DUF2051 PF09738.4 GAO86819.1 - 0.18 11.0 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF2040 PF09745.4 GAO86820.1 - 7.4e-42 142.1 15.9 7.4e-42 142.1 11.0 3.8 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 GAO86821.1 - 1.1e-26 93.6 0.5 2.1e-26 92.6 0.4 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 GAO86822.1 - 2.2e-57 194.0 0.0 2.9e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-C3HC4_2 PF13923.1 GAO86823.1 - 2.6e-08 33.7 12.8 3.6e-05 23.7 1.5 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO86823.1 - 4.8e-05 23.1 11.5 0.0096 15.7 3.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 GAO86823.1 - 0.0002 20.9 13.1 0.00041 20.0 4.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAO86823.1 - 0.00038 20.0 13.9 0.0075 15.9 4.4 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO86823.1 - 0.00095 18.8 3.6 0.00095 18.8 2.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 GAO86823.1 - 0.0014 18.2 2.2 0.0014 18.2 1.5 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAO86823.1 - 0.0045 16.2 4.5 0.0045 16.2 3.1 3.4 2 2 1 3 3 2 2 Rtf2 RING-finger FYVE PF01363.16 GAO86823.1 - 0.005 16.7 10.9 0.022 14.6 2.3 3.2 2 1 1 3 3 3 1 FYVE zinc finger Transcrip_act PF04949.8 GAO86823.1 - 0.0053 16.4 8.2 0.0053 16.4 5.7 2.4 1 1 1 2 2 2 1 Transcriptional activator Atg14 PF10186.4 GAO86823.1 - 0.025 13.5 11.5 0.049 12.5 8.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF780 PF05611.6 GAO86823.1 - 0.1 13.2 0.2 0.1 13.2 0.1 1.8 2 1 0 2 2 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Vps39_2 PF10367.4 GAO86823.1 - 0.42 10.7 6.7 0.091 12.9 0.7 2.7 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.1 GAO86823.1 - 2.8 7.8 13.0 0.19 11.6 1.4 3.0 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Sec7 PF01369.15 GAO86824.1 - 9.7e-42 142.7 0.0 2.1e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain SET PF00856.23 GAO86824.1 - 1.3e-14 54.8 0.9 1.4e-13 51.4 0.0 3.0 3 0 0 3 3 3 1 SET domain PH_9 PF15410.1 GAO86824.1 - 2.4e-07 30.9 0.1 5.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAO86824.1 - 0.00043 20.4 0.2 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 PH domain Peptidase_M14 PF00246.19 GAO86825.1 - 1.4e-67 228.2 0.0 2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 GAO86825.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide AA_permease PF00324.16 GAO86826.1 - 2.4e-124 415.3 40.3 2.9e-124 415.0 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO86826.1 - 9.2e-36 123.2 43.2 1.1e-35 123.0 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4500 PF14937.1 GAO86826.1 - 0.33 10.8 2.5 2.8 7.8 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4500) NicO PF03824.11 GAO86828.1 - 4.1e-57 193.6 19.8 1.3e-55 188.6 2.9 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 GAO86828.1 - 0.02 13.7 8.1 0.024 13.4 3.4 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF4231 PF14015.1 GAO86828.1 - 0.57 10.1 8.7 0.36 10.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DNA_pol_lambd_f PF10391.4 GAO86829.1 - 1.8e-21 75.4 1.4 4.4e-21 74.1 0.9 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 GAO86829.1 - 8.5e-19 67.0 0.1 3.2e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 GAO86829.1 - 5.7e-16 58.5 0.0 2e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 GAO86829.1 - 2.1e-08 34.2 0.2 5.6e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HAD PF12710.2 GAO86830.1 - 5.2e-19 69.1 0.2 1.3e-18 67.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAO86830.1 - 8.2e-17 61.0 0.1 1.4e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAO86830.1 - 9.2e-15 55.6 0.1 6.4e-14 52.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO86830.1 - 3.8e-11 42.7 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO86830.1 - 0.0041 16.7 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAO86830.1 - 0.017 15.3 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 GAO86831.1 - 5.2e-16 59.1 0.0 9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAO86831.1 - 7.7e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 GAO86832.1 - 3.7e-64 216.7 16.8 4.5e-64 216.4 11.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 GAO86832.1 - 0.16 12.0 13.1 0.32 11.0 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1510 PF07423.6 GAO86832.1 - 3.1 7.1 13.2 4.3 6.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med22 PF06179.7 GAO86833.1 - 4e-23 81.5 1.2 5.1e-23 81.1 0.8 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Terminase_2 PF03592.11 GAO86833.1 - 0.032 14.5 0.6 0.043 14.0 0.4 1.3 1 1 0 1 1 1 0 Terminase small subunit FlhC PF05280.6 GAO86833.1 - 0.065 12.6 0.1 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) VPS28 PF03997.7 GAO86833.1 - 0.075 12.6 0.1 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 VPS28 protein MxiH PF09392.5 GAO86833.1 - 4.3 7.9 5.6 1.9 9.1 1.4 2.1 2 1 0 2 2 2 0 Type III secretion needle MxiH like DHFR_1 PF00186.14 GAO86834.1 - 1.1e-23 83.6 0.0 7.5e-14 51.6 0.0 2.2 1 1 1 2 2 2 2 Dihydrofolate reductase Ribosomal_60s PF00428.14 GAO86834.1 - 0.0015 18.8 4.4 0.0027 18.0 3.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fe-ADH_2 PF13685.1 GAO86834.1 - 0.092 12.0 0.2 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Med3 PF11593.3 GAO86834.1 - 0.096 11.9 0.4 0.11 11.7 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Adeno_VII PF03228.9 GAO86834.1 - 0.48 11.0 4.3 6.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Adenoviral core protein VII Voltage_CLC PF00654.15 GAO86835.1 - 4.9e-93 311.9 25.9 1.1e-92 310.8 16.3 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel MFS_1 PF07690.11 GAO86836.1 - 9.2e-44 149.5 23.6 9.2e-44 149.5 16.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86836.1 - 4.7e-13 48.5 6.9 4.7e-13 48.5 4.8 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAO86836.1 - 5.2e-09 34.8 4.3 1e-06 27.2 2.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Lipase_GDSL_2 PF13472.1 GAO86837.1 - 2.8e-26 92.7 0.0 3.5e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO86837.1 - 1.4e-19 70.9 0.0 1.7e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP_ATPgrasp_1 PF04174.8 GAO86837.1 - 0.049 12.2 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Isochorismatase PF00857.15 GAO86838.1 - 3.1e-29 102.1 0.0 4.3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 GAO86839.1 - 3.6e-78 262.1 0.1 5.9e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 GAO86839.1 - 4.1e-60 201.9 2.2 4.1e-60 201.9 1.5 1.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 GAO86839.1 - 0.0072 15.6 0.1 0.016 14.4 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate kinase QRPTase_C PF01729.14 GAO86839.1 - 0.016 14.7 0.1 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain eIF-5_eIF-2B PF01873.12 GAO86840.1 - 2.8e-39 133.6 0.0 4.6e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 GAO86840.1 - 1.4e-25 89.0 0.2 4.3e-25 87.4 0.2 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon HEAT_EZ PF13513.1 GAO86841.1 - 2.6 8.6 9.5 0.7 10.4 0.5 4.1 4 0 0 4 4 4 0 HEAT-like repeat DNA_ligase_A_M PF01068.16 GAO86842.1 - 3.2e-57 193.1 1.7 8.9e-55 185.1 1.2 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAO86842.1 - 1.4e-55 187.8 1.3 2.1e-55 187.2 0.1 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAO86842.1 - 3e-28 98.0 0.0 2e-27 95.4 0.0 2.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Peptidase_S9 PF00326.16 GAO86843.1 - 7.6e-54 182.1 0.2 1.3e-53 181.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO86843.1 - 4.4e-13 49.2 0.1 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO86843.1 - 7.3e-11 42.3 0.5 1.8e-10 41.1 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 GAO86843.1 - 0.0037 16.8 2.6 5 6.9 0.1 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat VTC PF09359.5 GAO86844.1 - 2.3e-102 341.8 0.3 2.3e-102 341.8 0.2 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 GAO86844.1 - 6.8e-23 81.8 15.7 4.6e-21 75.8 8.8 3.4 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 GAO86844.1 - 1.3e-09 38.1 4.5 1.3e-09 38.1 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.18 GAO86845.1 - 4.8e-141 469.3 0.0 6.5e-141 468.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAO86845.1 - 7.9e-24 84.4 0.0 2.8e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO86845.1 - 7e-06 25.3 0.0 0.00024 20.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO86845.1 - 1.4e-05 24.8 0.0 3.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAO86845.1 - 0.0013 18.3 0.0 0.0038 16.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAO86845.1 - 0.088 12.2 0.1 4.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF221 PF02714.10 GAO86846.1 - 2.6e-108 361.7 27.3 2.6e-108 361.7 18.9 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAO86846.1 - 6.9e-46 155.6 0.4 6.9e-46 155.6 0.3 3.8 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAO86846.1 - 2.2e-14 53.0 0.0 6.8e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAO86846.1 - 5.6e-10 39.5 10.9 8.6e-05 22.9 1.1 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4463) GP41 PF00517.12 GAO86846.1 - 0.00025 20.6 1.5 0.0044 16.5 0.5 2.7 2 0 0 2 2 2 1 Retroviral envelope protein Ank_2 PF12796.2 GAO86847.1 - 8.3e-06 26.0 0.0 4.4e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAO86847.1 - 0.032 14.0 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 GAO86847.1 - 0.049 14.1 0.0 3.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SDA1 PF05285.7 GAO86847.1 - 0.37 10.0 3.6 0.47 9.6 2.5 1.1 1 0 0 1 1 1 0 SDA1 Band_7 PF01145.20 GAO86848.1 - 4.4e-24 85.3 2.7 6.2e-24 84.8 1.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2695 PF10905.3 GAO86848.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) CSTF2_hinge PF14327.1 GAO86849.1 - 5.1e-31 106.6 2.2 5.1e-31 106.6 1.5 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 GAO86849.1 - 1.9e-19 69.0 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86849.1 - 3.2e-16 59.0 0.0 5.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 GAO86849.1 - 8.4e-15 53.7 12.4 8.4e-15 53.7 8.6 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 GAO86849.1 - 2.2e-07 30.6 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 GAO86849.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RrnaAD PF00398.15 GAO86849.1 - 0.051 12.5 0.0 0.23 10.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Lyase_aromatic PF00221.14 GAO86850.1 - 1.1e-163 545.0 5.5 1.5e-163 544.6 3.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase SNF2_N PF00176.18 GAO86851.1 - 4.2e-20 71.7 1.2 4.1e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 GAO86851.1 - 9.1e-19 67.7 0.0 2.8e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 GAO86851.1 - 0.00032 20.4 0.0 0.0008 19.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 GAO86851.1 - 0.52 10.0 24.0 0.6 9.8 7.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAO86851.1 - 3.5 7.7 23.5 1.1 9.3 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 2Fe-2S_thioredx PF01257.14 GAO86852.1 - 3.4e-60 201.8 0.0 4.3e-60 201.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.17 GAO86854.1 - 4.6e-77 259.1 0.0 5.3e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 GAO86854.1 - 0.0067 16.4 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Sua5_yciO_yrdC PF01300.13 GAO86855.1 - 1.1e-57 194.1 0.0 2.2e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 GAO86855.1 - 1.5e-26 92.8 0.0 3.1e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3441 PF11923.3 GAO86856.1 - 2.1e-38 130.3 0.1 9.8e-38 128.2 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 GAO86856.1 - 2.2e-32 112.2 18.7 2.2e-32 112.2 12.9 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 GAO86856.1 - 7.1e-16 57.8 0.0 1.8e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 GAO86857.1 - 1.2e-12 47.6 0.0 2.2e-11 43.6 0.1 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 GAO86859.1 - 4.5e-26 90.2 0.0 5e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 GAO86860.1 - 5.2e-33 113.6 0.2 6.7e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e OB_NTP_bind PF07717.11 GAO86862.1 - 3.3e-19 68.8 0.0 8e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAO86862.1 - 6.9e-17 61.3 0.2 6.9e-17 61.3 0.1 2.5 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAO86862.1 - 1e-11 44.5 0.0 4.1e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAO86862.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAO86862.1 - 0.0025 17.2 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAO86862.1 - 0.02 15.2 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 GAO86862.1 - 0.042 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 GAO86862.1 - 0.11 11.5 0.0 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 KaiC F-box-like PF12937.2 GAO86863.1 - 2.7e-09 36.5 0.3 6.2e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO86863.1 - 5.1e-05 22.8 0.5 0.00013 21.5 0.2 1.8 2 0 0 2 2 2 1 F-box domain MIT PF04212.13 GAO86863.1 - 0.025 14.4 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 GAO86863.1 - 0.026 14.1 0.3 0.054 13.1 0.2 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 GAO86863.1 - 0.071 13.0 0.3 0.78 9.8 0.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 GAO86864.1 - 2.1e-59 197.2 0.8 1.5e-19 69.4 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein CorA PF01544.13 GAO86864.1 - 5e-11 42.1 1.7 5e-11 42.1 1.2 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 GAO86864.1 - 3.1e-05 23.3 0.1 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAO86864.1 - 0.00021 20.9 0.0 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Cpn60_TCP1 PF00118.19 GAO86865.1 - 3.9e-118 395.1 7.9 4.5e-118 394.9 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_Eps PF04627.8 GAO86867.1 - 7.1e-23 79.9 2.7 7.1e-23 79.9 1.8 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 GAO86868.1 - 5.8e-60 201.3 0.0 9.3e-60 200.6 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fungal_trans PF04082.13 GAO86869.1 - 3.2e-12 45.9 0.6 8.1e-12 44.5 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86869.1 - 4.6e-08 32.8 10.6 4.6e-08 32.8 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 GAO86870.1 - 1.6e-17 63.6 8.7 2.1e-17 63.2 6.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Isochorismatase PF00857.15 GAO86871.1 - 5.2e-37 127.4 0.2 5.8e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 GAO86872.1 - 1.3e-06 27.4 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86872.1 - 0.00062 19.6 4.2 0.0013 18.5 2.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 GAO86873.1 - 2.7e-32 112.1 0.0 2.6e-28 99.0 0.0 2.9 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO86873.1 - 4.8e-32 111.2 0.0 8.1e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAO86873.1 - 0.001 19.0 0.4 0.0039 17.1 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO86873.1 - 0.0019 17.1 0.0 0.005 15.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO86873.1 - 0.0065 16.3 0.1 0.027 14.3 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO86873.1 - 0.038 12.9 0.8 1.1 8.0 0.6 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 GAO86873.1 - 0.12 11.7 1.2 0.32 10.4 0.8 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cutinase PF01083.17 GAO86874.1 - 9.6e-53 178.5 0.0 1.1e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAO86874.1 - 0.0006 19.3 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 GAO86874.1 - 0.0071 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 GAO86874.1 - 0.073 12.9 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAO86874.1 - 0.098 12.0 0.1 0.17 11.3 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pyr_redox_3 PF13738.1 GAO86875.1 - 3.2e-24 86.1 0.0 5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO86875.1 - 4.8e-13 48.1 0.0 7.8e-11 40.8 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO86875.1 - 2.2e-07 30.1 0.0 1.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO86875.1 - 2.2e-06 27.7 0.0 4.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO86875.1 - 5.3e-06 26.3 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO86875.1 - 4.3e-05 22.5 0.0 0.18 10.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO86875.1 - 0.00088 19.0 1.1 0.1 12.3 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAO86875.1 - 0.043 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAO86875.1 - 0.24 10.4 0.8 1.2 8.1 0.0 2.2 3 0 0 3 3 3 0 Thi4 family NAGLU PF05089.7 GAO86876.1 - 5.7e-133 442.7 8.4 7.8e-133 442.3 5.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAO86876.1 - 5.8e-80 268.4 7.6 9.7e-80 267.7 5.3 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAO86876.1 - 3.2e-22 77.9 0.1 1.6e-21 75.7 0.0 2.3 3 0 0 3 3 3 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF3068 PF11271.3 GAO86876.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Shisa PF13908.1 GAO86877.1 - 0.00085 19.5 0.0 0.00097 19.3 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MLANA PF14991.1 GAO86877.1 - 0.027 14.4 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A TMEM154 PF15102.1 GAO86877.1 - 0.039 13.6 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3824 PF12868.2 GAO86877.1 - 0.043 14.7 1.8 0.053 14.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) EphA2_TM PF14575.1 GAO86877.1 - 0.06 13.7 0.0 0.076 13.4 0.0 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Esterase_phd PF10503.4 GAO86878.1 - 3.4e-25 88.5 1.4 4.6e-25 88.1 0.9 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAO86878.1 - 1.8e-10 40.4 0.5 2.9e-10 39.7 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO86878.1 - 1.1e-06 28.4 0.2 1.5e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAO86878.1 - 0.001 17.9 1.0 0.0019 16.9 0.7 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAO86878.1 - 0.0025 17.7 0.0 0.0052 16.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAO86878.1 - 0.0031 17.1 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 GAO86878.1 - 0.0042 16.5 0.7 0.0058 16.0 0.5 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAO86878.1 - 0.0069 15.9 0.1 0.009 15.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 GAO86878.1 - 0.013 14.1 1.1 0.018 13.6 0.7 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 BAAT_C PF08840.6 GAO86878.1 - 0.02 14.5 0.2 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 GAO86878.1 - 0.035 13.5 0.1 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 GAO86878.1 - 0.11 11.9 5.4 0.16 11.3 3.7 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.11 GAO86879.1 - 3e-32 111.7 45.4 2.1e-30 105.6 16.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO86879.1 - 4.4e-29 101.3 21.2 4.2e-28 98.1 14.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.14 GAO86879.1 - 0.00047 18.8 9.6 0.00047 18.8 6.6 1.5 2 0 0 2 2 2 1 LacY proton/sugar symporter PIRT PF15099.1 GAO86879.1 - 0.011 14.9 0.3 0.028 13.6 0.2 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TrkH PF02386.11 GAO86880.1 - 3.5e-107 358.0 7.6 8.9e-107 356.7 2.1 2.0 2 0 0 2 2 2 2 Cation transport protein Orthopox_A36R PF05950.6 GAO86880.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein TB2_DP1_HVA22 PF03134.14 GAO86881.1 - 8.4e-29 99.1 7.2 1.2e-28 98.6 5.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family URO-D PF01208.12 GAO86881.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Ifi-6-16 PF06140.8 GAO86882.1 - 0.0081 15.9 5.9 0.013 15.3 4.1 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family MIF4G PF02854.14 GAO86883.1 - 5.1e-50 169.8 0.0 1e-49 168.7 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 GAO86883.1 - 1.7e-24 85.5 1.1 8.1e-24 83.3 0.8 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.21 GAO86884.1 - 1.6e-20 73.7 0.0 3.5e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family Kazal_1 PF00050.16 GAO86884.1 - 0.13 12.3 0.5 0.28 11.2 0.3 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Ashwin PF15323.1 GAO86884.1 - 1.9 8.4 14.2 1.2 9.0 6.8 2.3 2 1 0 2 2 2 0 Developmental protein DUF3399 PF11879.3 GAO86885.1 - 2.9 8.1 5.5 1.9 8.7 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Cellulase PF00150.13 GAO86886.1 - 1.1e-56 192.1 0.4 1.6e-56 191.6 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAO86886.1 - 7.9e-15 54.2 12.1 7.9e-15 54.2 8.4 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain TFIIA PF03153.8 GAO86886.1 - 8.6 6.1 10.9 13 5.5 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NRDE PF05742.7 GAO86887.1 - 1.5e-47 162.1 0.0 2.3e-47 161.6 0.0 1.3 1 1 0 1 1 1 1 NRDE protein p450 PF00067.17 GAO86888.1 - 1.9e-59 201.3 0.0 2.7e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_N PF09825.4 GAO86890.1 - 4.3e-142 473.2 0.0 8e-142 472.3 0.0 1.4 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 GAO86890.1 - 4.5e-20 71.9 0.0 8.7e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 GAO86890.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CHCH PF06747.8 GAO86891.1 - 0.11 12.4 0.9 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 CHCH domain Mgm101p PF06420.7 GAO86892.1 - 1.1e-90 301.5 0.0 1.4e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MS_channel PF00924.13 GAO86893.1 - 6.4e-20 71.3 0.9 1.1e-19 70.6 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAO86893.1 - 0.00028 19.9 0.1 0.00062 18.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAO86893.1 - 0.0017 18.0 0.0 0.0046 16.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 GAO86893.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 GAO86893.1 - 0.068 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 EF hand MurB_C PF02873.11 GAO86894.1 - 3.9e-22 77.9 0.0 7.2e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.18 GAO86894.1 - 1e-17 63.9 0.1 1.7e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain EPSP_synthase PF00275.15 GAO86895.1 - 4.2e-83 279.1 3.4 4.8e-83 278.9 2.3 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PhyH PF05721.8 GAO86897.1 - 9.7e-22 78.0 0.0 1.5e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-RING_2 PF13639.1 GAO86899.1 - 3.6e-15 55.4 5.3 5.8e-15 54.8 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO86899.1 - 1e-07 31.9 1.8 1.8e-07 31.1 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAO86899.1 - 1.3e-07 31.1 3.6 2e-07 30.5 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO86899.1 - 4.6e-07 29.7 5.2 7.7e-07 29.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO86899.1 - 4.7e-06 26.2 2.5 8e-06 25.4 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAO86899.1 - 1e-05 25.0 1.6 1.7e-05 24.3 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAO86899.1 - 0.0018 17.8 3.1 0.0032 17.0 2.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 GAO86899.1 - 0.002 17.9 2.9 0.0041 16.9 2.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 GAO86899.1 - 0.041 13.8 2.4 0.072 13.1 1.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 GAO86899.1 - 0.68 9.8 6.0 1.3 8.9 4.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 GAO86899.1 - 1.2 9.1 4.7 7.1 6.6 3.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 GAO86899.1 - 3.3 7.4 5.2 20 4.9 3.6 2.1 1 1 1 2 2 2 0 PHD-finger Aminotran_1_2 PF00155.16 GAO86900.1 - 2.6e-80 270.1 0.0 3e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 GAO86901.1 - 2.1e-18 65.9 4.6 2.7e-18 65.5 1.3 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 GAO86901.1 - 0.00023 20.7 3.3 0.00077 19.1 2.3 1.9 1 0 0 1 1 1 1 SNARE domain TPR_11 PF13414.1 GAO86902.1 - 1.9e-18 65.8 6.5 1.3e-09 37.5 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAO86902.1 - 2e-15 55.6 4.2 2.4e-07 30.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO86902.1 - 3.4e-14 51.5 3.8 5.7e-05 22.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAO86902.1 - 4.3e-09 36.1 0.4 2.8e-05 23.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO86902.1 - 5.2e-09 35.2 1.8 0.00022 20.7 0.0 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAO86902.1 - 6.7e-07 28.6 1.0 6.7e-05 22.3 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAO86902.1 - 1.1e-05 25.1 0.1 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO86902.1 - 3.4e-05 24.3 0.9 0.0047 17.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.19 GAO86902.1 - 3.9e-05 23.2 0.1 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 GAO86902.1 - 6.1e-05 23.2 0.2 4.9 7.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAO86902.1 - 0.00089 19.2 0.1 0.48 10.7 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO86902.1 - 0.0017 18.4 2.4 0.018 15.1 0.2 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAO86902.1 - 0.0053 17.2 0.3 0.21 12.3 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF605 PF04652.11 GAO86902.1 - 1.6 8.0 7.2 2.3 7.5 5.0 1.3 1 0 0 1 1 1 0 Vta1 like Sod_Cu PF00080.15 GAO86903.1 - 2.9e-16 59.9 0.0 4.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 GAO86903.1 - 1.2e-12 47.8 0.1 2.7e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 GAO86904.1 - 1.2e-64 218.0 0.0 2e-64 217.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86904.1 - 4.4e-27 94.7 0.0 7.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO86904.1 - 0.32 10.6 3.0 0.84 9.3 2.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family HlyD PF00529.15 GAO86904.1 - 1.1 8.5 10.7 1.5 8.0 7.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Methyltransf_28 PF02636.12 GAO86906.1 - 5.7e-81 271.6 0.0 8e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.17 GAO86906.1 - 3e-05 23.5 0.0 8.1e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86906.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86906.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.15 GAO86907.1 - 6.7e-14 52.2 0.0 9.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 GAO86908.1 - 2.1e-12 46.2 0.4 3.9e-12 45.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.14 GAO86910.1 - 4.5e-220 731.1 0.3 5.2e-220 730.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PWI PF01480.12 GAO86911.1 - 2e-11 43.7 0.5 4.6e-11 42.6 0.3 1.6 1 0 0 1 1 1 1 PWI domain SUKH_6 PF14568.1 GAO86911.1 - 0.018 15.4 0.1 0.084 13.3 0.0 2.1 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall RRM_1 PF00076.17 GAO86911.1 - 0.053 13.1 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MR_MLE_C PF13378.1 GAO86912.1 - 3.6e-18 65.5 0.1 1.8e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAO86912.1 - 5.7e-15 55.6 0.1 5.7e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAO86912.1 - 6.4e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TIM21 PF08294.6 GAO86913.1 - 5.4e-42 142.8 0.0 6.9e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 GAO86913.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 GAO86914.1 - 3.5e-34 117.0 0.6 6.1e-34 116.3 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 GAO86914.1 - 4 7.0 5.8 0.59 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Pterin_bind PF00809.17 GAO86915.1 - 3.6e-69 232.3 0.0 6.2e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 GAO86915.1 - 5.3e-40 136.0 0.0 8.5e-40 135.4 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 GAO86916.1 - 4.6e-72 242.9 1.5 5.4e-72 242.7 1.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAO86916.1 - 5.2e-09 35.4 0.6 9e-09 34.6 0.4 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAO86916.1 - 5.5e-06 25.4 2.4 9.1e-06 24.7 1.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAO86916.1 - 0.00086 18.3 1.9 0.0017 17.3 1.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Transp_cyt_pur PF02133.10 GAO86917.1 - 2.1e-45 155.0 34.4 2.6e-45 154.7 23.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin eIF3g PF12353.3 GAO86918.1 - 8.7e-46 154.9 2.1 1.3e-45 154.3 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAO86918.1 - 8.7e-17 60.5 0.0 1.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86918.1 - 4.5e-13 48.9 0.0 8.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO86918.1 - 7.7e-08 32.0 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 GAO86919.1 - 1.8e-39 135.6 0.1 2.9e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AMP-binding PF00501.23 GAO86920.1 - 1.7e-77 260.5 0.0 2.6e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO86920.1 - 0.0071 17.2 0.1 0.018 15.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 GAO86921.1 - 1.2e-11 44.3 0.0 8.5e-07 28.5 0.0 2.6 2 1 1 3 3 3 2 Putative methyltransferase TMF_TATA_bd PF12325.3 GAO86922.1 - 0.28 10.8 6.3 0.48 10.1 4.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HSP70 PF00012.15 GAO86923.1 - 1.1e-267 888.8 16.4 1.2e-267 888.6 11.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO86923.1 - 3.6e-16 58.6 5.0 2.3e-14 52.7 0.9 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 GAO86923.1 - 0.00089 18.9 0.1 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 GAO86923.1 - 0.018 14.7 2.5 0.04 13.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) FtsA PF14450.1 GAO86923.1 - 0.072 12.9 13.5 18 5.1 4.0 4.9 2 2 0 2 2 2 0 Cell division protein FtsA DUF2415 PF10313.4 GAO86924.1 - 7.3e-16 57.5 0.0 1.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 GAO86924.1 - 0.013 15.4 2.1 1.2 9.1 0.3 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat DSHCT PF08148.7 GAO86925.1 - 1.3e-61 206.9 0.8 2.4e-61 206.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAO86925.1 - 2.6e-19 69.3 0.0 5.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO86925.1 - 1.2e-06 28.2 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO86925.1 - 0.016 15.0 0.0 0.19 11.5 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.1 GAO86925.1 - 0.019 14.1 0.1 1 8.4 0.0 2.4 2 0 0 2 2 2 0 rRNA-processing arch domain BRCA2 PF00634.13 GAO86925.1 - 0.058 12.6 0.2 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 BRCA2 repeat IBN_N PF03810.14 GAO86926.1 - 4.6e-15 55.2 2.6 2.9e-12 46.3 0.0 4.5 5 0 0 5 5 5 1 Importin-beta N-terminal domain Cse1 PF08506.5 GAO86926.1 - 3.1e-08 32.5 0.0 6.2e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 GAO86926.1 - 2.5e-05 24.4 0.0 0.055 13.7 0.0 3.0 2 1 0 2 2 2 2 HEAT repeats Xpo1 PF08389.7 GAO86926.1 - 8.2e-05 22.5 0.6 0.017 15.0 0.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein DUF2435 PF10363.4 GAO86926.1 - 0.0018 18.1 0.8 0.0096 15.8 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Terpene_synth_C PF03936.11 GAO86926.1 - 0.0051 16.0 0.0 0.019 14.1 0.0 1.9 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SDA1 PF05285.7 GAO86926.1 - 0.97 8.6 6.5 1.5 7.9 4.5 1.2 1 0 0 1 1 1 0 SDA1 RRM_1 PF00076.17 GAO86928.1 - 5e-10 38.8 0.0 1.5e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO86928.1 - 5.8e-08 32.5 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO86928.1 - 2.6e-05 23.9 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAO86928.1 - 0.0097 15.7 0.3 0.023 14.5 0.2 1.8 1 1 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 GAO86928.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 GAO86929.1 - 0.012 15.0 0.8 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 GAO86929.1 - 0.036 14.4 3.1 3.7 7.9 0.2 2.5 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.5 GAO86930.1 - 9 6.4 8.7 0.92 9.6 0.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CPSase_L_D2 PF02786.12 GAO86931.1 - 1.9e-109 363.8 0.0 7.7e-85 283.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 GAO86931.1 - 2.6e-42 143.4 0.0 5.8e-42 142.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAO86931.1 - 2.8e-37 128.2 0.1 1.8e-20 73.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 GAO86931.1 - 1.5e-33 115.1 0.0 6.7e-17 61.5 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 GAO86931.1 - 1e-26 93.4 0.0 3.7e-10 39.0 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAO86931.1 - 1.2e-18 67.0 0.1 5.7e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAO86931.1 - 1.3e-17 63.9 0.3 9.9e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 GAO86931.1 - 5.7e-08 32.4 0.0 0.0015 18.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 GAO86931.1 - 4.4e-05 23.1 0.2 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 GAO86931.1 - 4.9e-05 22.6 0.0 0.043 13.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain MCPsignal PF00015.16 GAO86931.1 - 0.083 12.4 0.1 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SET PF00856.23 GAO86932.1 - 3.9e-13 50.0 0.0 7.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.16 GAO86933.1 - 5.3e-35 118.8 0.4 8.2e-35 118.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 GAO86934.1 - 2e-29 101.8 12.9 2.3e-29 101.6 8.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 GAO86934.1 - 0.14 10.3 2.0 0.14 10.3 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPT2 PF08243.6 GAO86935.1 - 0.00053 20.2 17.1 0.00053 20.2 11.8 2.5 2 1 0 2 2 2 1 SPT2 chromatin protein Carb_kinase PF01256.12 GAO86936.1 - 1.1e-53 182.0 0.2 4.2e-53 180.1 0.1 1.8 1 1 0 1 1 1 1 Carbohydrate kinase EGF_CA PF07645.10 GAO86937.1 - 8.4e-06 25.6 4.9 8.4e-06 25.6 3.4 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 GAO86937.1 - 0.001 18.9 5.7 0.001 18.9 3.9 2.0 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 GAO86937.1 - 0.0012 18.9 7.0 0.0012 18.9 4.9 2.5 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 GAO86937.1 - 0.0048 16.5 0.0 0.0048 16.5 0.0 2.6 4 0 0 4 4 4 1 Complement Clr-like EGF-like EGF PF00008.22 GAO86937.1 - 0.036 14.0 5.3 0.036 14.0 3.7 2.2 2 1 0 2 2 2 0 EGF-like domain MCM PF00493.18 GAO86938.1 - 2.4e-136 453.8 0.1 8.6e-136 452.0 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 GAO86938.1 - 2.8e-29 102.0 0.1 9.6e-29 100.3 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO86938.1 - 2e-07 30.3 0.1 2e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO86938.1 - 2.2e-06 27.4 0.0 5.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAO86938.1 - 0.026 14.1 0.0 0.093 12.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAO86938.1 - 0.12 11.8 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 GAO86938.1 - 0.41 10.6 2.8 36 4.2 0.0 3.3 2 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 GAO86939.1 - 1.2e-53 180.8 0.0 3.1e-43 147.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 GAO86939.1 - 2.7e-29 101.0 0.3 6.2e-29 99.8 0.2 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 GAO86939.1 - 1.1e-09 38.6 2.0 8.5e-05 22.6 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 GAO86939.1 - 3.1e-07 30.0 0.1 0.0024 17.5 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 GAO86939.1 - 6.7e-07 28.8 0.3 0.0029 17.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 GAO86939.1 - 8.5e-07 28.7 0.7 0.0011 18.6 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 GAO86939.1 - 2.8e-06 28.1 0.0 0.17 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAO86939.1 - 3.8e-06 26.9 0.0 0.094 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 GAO86939.1 - 3.4e-05 23.7 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO86939.1 - 8.6e-05 22.8 0.4 0.1 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAO86939.1 - 0.00031 19.8 0.0 0.007 15.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAO86939.1 - 0.00036 20.6 2.8 0.78 9.8 0.1 4.1 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 GAO86939.1 - 0.0019 17.3 0.0 0.97 8.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 GAO86939.1 - 0.0035 17.0 0.1 1.2 8.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAO86939.1 - 0.0037 17.4 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 GAO86939.1 - 0.0038 16.6 3.2 3.5 6.9 0.1 4.0 2 2 0 3 3 3 1 AAA domain UPF0079 PF02367.12 GAO86939.1 - 0.0085 15.7 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 GAO86939.1 - 0.0087 15.9 0.2 0.48 10.2 0.0 3.1 3 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 GAO86939.1 - 0.0089 14.7 0.0 0.63 8.6 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus KaiC PF06745.8 GAO86939.1 - 0.012 14.7 0.2 2 7.5 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 GAO86939.1 - 0.018 14.9 0.0 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 GAO86939.1 - 0.024 14.1 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 GAO86939.1 - 0.028 14.7 0.1 6.4 7.0 0.0 3.2 3 0 0 3 3 3 0 ABC transporter KAP_NTPase PF07693.9 GAO86939.1 - 0.033 13.1 0.6 1 8.2 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.21 GAO86939.1 - 0.034 13.6 0.0 3.1 7.2 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAO86939.1 - 0.035 13.2 0.2 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 GAO86939.1 - 0.048 13.3 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 GAO86939.1 - 0.058 12.6 0.1 6.1 6.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 GAO86939.1 - 0.065 12.2 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 GAO86939.1 - 0.066 12.1 0.2 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 GAO86939.1 - 0.19 11.3 0.8 25 4.4 0.0 3.1 2 2 1 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 GAO86939.1 - 0.2 10.4 0.2 7.2 5.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 GAO86939.1 - 0.49 9.8 2.4 7.6 5.9 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 GAO86940.1 - 2.1e-93 312.9 0.0 2.5e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO86940.1 - 2.1e-10 41.3 0.1 5.3e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 GAO86941.1 - 9e-18 64.9 0.2 1.7e-17 64.0 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO86941.1 - 4.3e-05 23.0 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAO86941.1 - 0.041 12.7 0.0 0.082 11.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain TetR_C_7 PF14246.1 GAO86941.1 - 0.12 12.6 0.8 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region Aldo_ket_red PF00248.16 GAO86944.1 - 9.4e-52 175.5 0.0 1.2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Baculo_gp64 PF03273.8 GAO86944.1 - 0.14 10.3 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family DUF706 PF05153.10 GAO86945.1 - 7.1e-132 438.3 4.8 9.6e-132 437.9 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 GAO86945.1 - 0.079 12.9 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 HD domain Exonuc_X-T_C PF08411.5 GAO86945.1 - 0.14 11.2 8.4 0.43 9.5 1.9 2.4 3 0 0 3 3 3 0 Exonuclease C-terminal GFO_IDH_MocA PF01408.17 GAO86946.1 - 6.2e-25 88.0 0.2 1.3e-24 86.9 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO86946.1 - 1.6e-06 27.8 0.0 4.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 GAO86946.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 7TMR-HDED PF07697.6 GAO86947.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 7TM-HD extracellular FAT PF02259.18 GAO86948.1 - 2.7e-131 437.7 0.3 2.7e-131 437.7 0.2 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 GAO86948.1 - 3.7e-60 202.4 1.3 1.6e-57 193.9 0.2 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 GAO86948.1 - 1.4e-56 191.5 0.3 3e-56 190.5 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 GAO86948.1 - 3.5e-41 139.3 1.3 2.9e-40 136.4 0.1 3.2 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 GAO86948.1 - 5.3e-15 55.4 16.9 0.00075 19.7 0.0 9.4 7 4 5 12 12 12 7 HEAT repeats HEAT_EZ PF13513.1 GAO86948.1 - 1.2e-14 54.2 10.3 0.021 15.3 0.0 10.9 7 2 3 12 12 12 4 HEAT-like repeat HEAT PF02985.17 GAO86948.1 - 7.2e-11 41.2 23.1 1 9.6 0.0 12.6 14 0 0 14 14 14 5 HEAT repeat FATC PF02260.15 GAO86948.1 - 7e-06 25.3 0.3 1.8e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 FATC domain Epimerase PF01370.16 GAO86949.1 - 1.3e-18 67.2 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO86949.1 - 2.1e-11 43.0 0.0 2.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO86949.1 - 1.2e-09 38.3 0.0 2.1e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO86949.1 - 3.1e-09 36.1 0.0 2e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAO86949.1 - 1.8e-06 27.9 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAO86949.1 - 0.00019 20.4 0.0 0.00033 19.6 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAO86949.1 - 0.0021 17.7 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 GAO86949.1 - 0.0055 15.9 0.1 0.011 14.9 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family Mit_ribos_Mrp51 PF11709.3 GAO86950.1 - 1.1e-101 340.1 0.0 1.3e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit B PF02216.11 GAO86950.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 B domain Ribosomal_S17e PF00833.13 GAO86951.1 - 1.1e-58 196.2 0.9 1.4e-58 195.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 GAO86951.1 - 0.038 14.6 0.5 0.058 14.0 0.3 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 GAO86952.1 - 4.4e-19 68.3 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family HpaP PF09483.5 GAO86952.1 - 1.1 9.1 9.3 1.8 8.4 4.5 2.2 2 1 0 2 2 2 0 Type III secretion protein (HpaP) SH3_9 PF14604.1 GAO86953.1 - 2.8e-08 33.2 1.8 1.1e-07 31.2 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAO86953.1 - 3.1e-08 32.8 2.1 9.8e-08 31.2 0.1 2.6 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 GAO86953.1 - 3.7e-07 29.5 0.0 8.1e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CWC25 PF12542.3 GAO86954.1 - 6.7e-24 84.1 0.2 6.7e-24 84.1 0.1 3.9 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 GAO86954.1 - 1.3e-14 53.9 10.0 1.3e-14 53.9 6.9 5.0 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Adaptin_N PF01602.15 GAO86955.1 - 4.5e-127 424.5 6.5 5.7e-127 424.2 4.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAO86955.1 - 2.5e-16 60.0 2.0 2.6e-15 56.7 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAO86955.1 - 7.9e-16 58.1 1.2 1.4e-08 34.8 0.0 4.6 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 GAO86955.1 - 5.6e-08 32.2 4.2 0.53 10.4 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.4 GAO86955.1 - 1.4e-05 24.7 0.1 0.29 10.8 0.0 4.1 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 GAO86955.1 - 0.0027 18.1 5.8 4.7 7.8 0.0 5.9 4 1 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 GAO86955.1 - 0.0074 15.6 0.8 2.7 7.2 0.1 3.0 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 GAO86955.1 - 0.012 15.4 2.7 2.6 8.0 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Carbpep_Y_N PF05388.6 GAO86955.1 - 0.033 14.3 0.5 31 4.7 0.0 3.4 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide DUF1077 PF06417.7 GAO86956.1 - 2.8e-53 178.5 1.2 3.4e-53 178.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Aminotran_5 PF00266.14 GAO86957.1 - 2.6e-10 39.5 0.0 1.7e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAO86957.1 - 0.0041 16.2 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fe-S_biosyn PF01521.15 GAO86958.1 - 3.4e-10 39.8 0.0 1.9e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Paf67 PF10255.4 GAO86959.1 - 1.1e-157 525.0 0.0 1.3e-157 524.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 GAO86959.1 - 0.072 13.0 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 GAO86960.1 - 5.6e-15 54.9 0.4 8e-15 54.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86960.1 - 7.6e-07 28.9 8.1 1.6e-06 27.8 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.14 GAO86961.1 - 3.7e-23 82.2 0.0 6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV AAR2 PF05282.6 GAO86962.1 - 7e-111 370.6 0.0 8.2e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 GAO86963.1 - 9.7e-41 138.3 0.4 1.2e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 GAO86964.1 - 1.2e-10 40.7 0.0 1.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 GAO86964.1 - 0.00087 19.1 0.1 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAO86964.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 GAO86964.1 - 0.022 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 GAO86964.1 - 0.038 13.4 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_S9 PF00380.14 GAO86965.1 - 1.4e-40 138.3 0.9 1.5e-40 138.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Alg14 PF08660.6 GAO86965.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Ribosomal_L13 PF00572.13 GAO86966.1 - 2.4e-40 137.5 0.0 3.2e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 GAO86967.1 - 9.6e-90 297.8 2.9 2.4e-50 170.2 1.0 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 GAO86967.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Deltaretro_Tax PF05599.6 GAO86967.1 - 0.16 12.3 0.3 0.28 11.5 0.2 1.4 1 0 0 1 1 1 0 Deltaretrovirus Tax protein MFS_1 PF07690.11 GAO86968.1 - 1.1e-45 155.8 41.3 6.5e-37 127.0 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAO86968.1 - 0.87 7.5 7.3 4.2 5.2 0.0 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SelP_N PF04592.9 GAO86969.1 - 0.078 12.3 4.6 0.096 12.0 3.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-H2C2_2 PF13465.1 GAO86970.1 - 3.1e-07 30.3 12.0 1.1e-05 25.4 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO86970.1 - 2.6e-06 27.3 13.9 0.00021 21.3 4.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 GAO86970.1 - 0.00039 20.4 3.9 0.00079 19.4 2.7 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 GAO86970.1 - 0.004 17.4 16.8 0.021 15.1 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAO86970.1 - 0.0045 17.0 4.7 0.066 13.3 0.7 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 GAO86970.1 - 0.18 11.6 1.4 0.33 10.7 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 GAO86970.1 - 0.61 9.8 8.6 0.31 10.8 1.0 2.5 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 GAO86970.1 - 0.67 10.2 5.3 2.1 8.6 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 GAO86970.1 - 7.5 6.3 8.4 10 5.9 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AA_permease_2 PF13520.1 GAO86971.1 - 5.2e-67 226.2 41.0 6.2e-67 225.9 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO86971.1 - 1e-17 63.7 34.0 1.3e-17 63.2 23.6 1.2 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.4 GAO86972.1 - 9.2e-30 102.1 0.4 1.1e-29 101.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Thioredoxin PF00085.15 GAO86973.1 - 2.8e-44 149.0 0.0 4.1e-24 84.2 0.0 4.5 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 GAO86973.1 - 2.2e-13 50.3 0.0 0.00011 22.0 0.0 5.0 4 1 1 5 5 5 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAO86973.1 - 4.7e-09 36.2 0.2 0.014 15.5 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAO86973.1 - 5.6e-09 36.1 2.0 0.0013 18.8 0.0 4.1 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAO86973.1 - 0.00062 19.7 0.7 0.024 14.6 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 GAO86973.1 - 0.0097 15.7 0.0 1.9 8.3 0.0 3.1 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 GAO86973.1 - 0.093 12.5 0.0 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain ETC_C1_NDUFA5 PF04716.9 GAO86974.1 - 1.2e-21 75.9 0.1 1.2e-21 75.9 0.1 3.1 4 0 0 4 4 4 1 ETC complex I subunit conserved region Coatomer_WDAD PF04053.9 GAO86975.1 - 5.2e-172 572.6 0.0 1e-171 571.6 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 GAO86975.1 - 8.5e-47 155.4 7.3 5.2e-10 38.8 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAO86975.1 - 0.00013 20.2 1.6 0.033 12.3 0.0 3.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAO86975.1 - 0.0041 16.8 0.0 2 8.2 0.0 3.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 GAO86976.1 - 1.5e-71 240.6 0.0 1.9e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO86976.1 - 7.1e-33 113.7 0.0 9.8e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAO86976.1 - 8.7e-10 38.9 0.7 2.1e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAO86976.1 - 0.00055 18.9 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ECH PF00378.15 GAO86977.1 - 1.3e-48 165.2 0.0 2.4e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ZZ PF00569.12 GAO86977.1 - 2.7e-11 42.8 5.7 4.7e-11 42.0 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 GAO86977.1 - 1.6e-07 31.3 0.0 4.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAO86977.1 - 1.7e-07 31.2 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mannitol_dh_C PF08125.8 GAO86978.1 - 1.4e-48 165.1 0.0 2e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAO86978.1 - 2.2e-18 66.6 1.6 6.9e-17 61.7 0.1 2.3 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 GAO86978.1 - 0.0019 17.8 1.2 0.0046 16.6 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO86978.1 - 0.047 13.4 0.8 0.09 12.4 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus B12-binding PF02310.14 GAO86978.1 - 0.078 12.8 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain SUR7 PF06687.7 GAO86979.1 - 4.1e-24 85.3 7.0 5e-24 85.0 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 GAO86979.1 - 1.6 8.3 13.0 0.025 14.2 3.2 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction LRR_4 PF12799.2 GAO86980.1 - 0.0023 17.5 7.2 9.5 5.9 0.2 5.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) MutS_III PF05192.13 GAO86980.1 - 0.062 13.0 0.5 0.66 9.7 0.3 2.4 1 1 0 1 1 1 0 MutS domain III Rad9 PF04139.8 GAO86981.1 - 7e-34 117.0 0.2 1.1e-33 116.3 0.1 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 GAO86981.1 - 0.054 12.2 0.5 0.61 8.8 0.1 2.1 1 1 1 2 2 2 0 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.13 GAO86982.1 - 1.3e-37 127.7 17.1 3.7e-08 33.4 0.0 7.1 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAO86982.1 - 4.7e-22 77.0 20.5 7.3e-07 28.6 0.1 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 GAO86982.1 - 0.86 9.4 6.4 8.2 6.2 0.2 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Sugar_tr PF00083.19 GAO86983.1 - 1.7e-23 82.9 24.4 2e-21 76.0 16.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2333 PF10095.4 GAO86983.1 - 0.14 10.7 0.0 0.34 9.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) DNA_pol_B PF00136.16 GAO86984.1 - 1.8e-115 386.4 4.3 1.8e-115 386.4 3.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 GAO86984.1 - 4.1e-69 231.7 0.4 8.1e-69 230.7 0.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 GAO86984.1 - 7.4e-39 133.4 0.0 1.5e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 GAO86984.1 - 1.8e-26 91.7 15.2 3e-25 87.7 6.2 3.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal Phos_pyr_kin PF08543.7 GAO86985.1 - 1.1e-81 273.6 1.6 1.5e-81 273.2 1.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 GAO86985.1 - 7.7e-55 185.8 0.4 1e-54 185.5 0.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 GAO86985.1 - 1.8e-06 27.3 0.5 3e-06 26.6 0.4 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 GAO86985.1 - 0.00087 18.5 0.3 0.0071 15.5 0.0 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 GAO86985.1 - 0.0011 18.2 0.9 0.0011 18.2 0.7 2.0 2 0 0 2 2 2 1 Carbohydrate kinase DEAD PF00270.24 GAO86986.1 - 1.1e-45 155.2 0.0 7.7e-44 149.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO86986.1 - 3e-28 97.4 0.0 6.7e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO86986.1 - 0.00055 19.8 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAO86986.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 GAO86986.1 - 0.013 15.2 0.2 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF1253 PF06862.7 GAO86986.1 - 0.036 12.4 0.0 1.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 GAO86986.1 - 0.047 13.4 0.0 6.8 6.5 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Lipase_GDSL PF00657.17 GAO86987.1 - 6.5e-07 29.4 3.7 1.3e-06 28.3 2.5 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAO86987.1 - 3e-06 27.5 3.0 1.1e-05 25.6 2.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PPR_2 PF13041.1 GAO86988.1 - 1.8e-22 79.0 0.0 1.6e-16 60.0 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 GAO86988.1 - 3.1e-06 27.0 0.6 0.0025 17.9 0.0 4.3 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 GAO86988.1 - 0.0016 18.2 2.6 0.04 13.8 0.1 3.5 3 0 0 3 3 3 1 PPR repeat Yip1 PF04893.12 GAO86989.1 - 1.6e-14 53.7 13.1 2.8e-14 52.9 9.0 1.5 1 1 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.13 GAO86990.1 - 1.7e-20 73.3 0.0 3.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain DEAD PF00270.24 GAO86991.1 - 8.3e-24 83.9 0.0 1.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO86991.1 - 4.5e-11 42.4 0.0 1.5e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 GAO86991.1 - 1.7e-09 38.1 0.3 2.2e-08 34.5 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Fungal_trans_2 PF11951.3 GAO86992.1 - 9.6e-14 50.7 0.1 1.5e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO86992.1 - 4.7e-07 29.6 10.1 1e-06 28.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_7 PF13176.1 GAO86992.1 - 0.058 13.2 0.0 0.95 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Formyl_trans_N PF00551.14 GAO86993.1 - 1.1e-39 135.8 0.1 1.3e-39 135.6 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.1 GAO86994.1 - 3.3e-15 55.6 5.3 5.2e-15 55.0 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO86994.1 - 6.1e-10 39.0 0.9 1.1e-09 38.2 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAO86994.1 - 4.9e-08 32.4 4.7 7.7e-08 31.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO86994.1 - 1.4e-07 31.3 4.4 2.2e-07 30.7 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO86994.1 - 5.7e-07 29.1 3.2 8.7e-07 28.5 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAO86994.1 - 6.3e-05 22.5 1.5 9.9e-05 21.9 1.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAO86994.1 - 7.2e-05 22.5 2.6 0.00018 21.3 1.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 GAO86994.1 - 0.0001 22.2 6.1 0.00016 21.6 4.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 GAO86994.1 - 0.008 15.6 1.7 0.017 14.6 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAO86994.1 - 0.027 14.1 2.2 0.057 13.1 1.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 GAO86994.1 - 0.054 13.4 2.6 0.097 12.6 1.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 GAO86994.1 - 0.054 13.0 3.8 0.085 12.4 2.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 GAO86994.1 - 0.18 11.8 2.5 0.32 11.0 1.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 GAO86994.1 - 0.6 9.8 3.9 0.99 9.1 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 GAO86994.1 - 0.67 9.7 3.6 1.5 8.6 2.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RNA_pol_I_TF PF04090.7 GAO86995.1 - 8.6e-10 38.2 0.0 2.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ECM11 PF15463.1 GAO86996.1 - 1.1e-43 148.7 2.1 3e-43 147.4 1.5 1.8 1 0 0 1 1 1 1 Extracellular mutant protein 11 VPS9 PF02204.13 GAO86997.1 - 3e-11 43.2 0.0 6.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 GAO86998.1 - 2.2e-06 27.3 0.0 6.8e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Sugar_tr PF00083.19 GAO86999.1 - 9e-81 271.7 21.0 1e-80 271.5 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO86999.1 - 1.5e-14 53.4 30.8 2.2e-12 46.3 16.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.6 GAO86999.1 - 0.049 13.8 0.2 2.8 8.1 0.0 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal ECH PF00378.15 GAO87000.1 - 9.7e-72 241.0 0.1 1.2e-71 240.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAO87000.1 - 0.0042 17.2 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 GAO87000.1 - 0.071 12.8 0.6 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 Rer1 PF03248.8 GAO87001.1 - 4.2e-82 273.9 4.8 4.7e-82 273.8 3.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.1 GAO87001.1 - 1.1 8.6 10.1 2.5 7.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) DUF962 PF06127.6 GAO87001.1 - 2.6 8.0 5.6 4.8 7.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF3419 PF11899.3 GAO87002.1 - 3.2e-157 523.1 0.0 4.7e-157 522.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 GAO87002.1 - 1.9e-13 50.4 0.0 5.1e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87002.1 - 6.2e-11 42.8 0.0 1.3e-09 38.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87002.1 - 2e-10 41.0 0.0 6.1e-10 39.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87002.1 - 2.2e-10 40.3 0.0 8.6e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87002.1 - 1e-08 35.1 0.0 1.5e-07 31.4 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87002.1 - 8.5e-08 32.5 0.0 2e-05 25.0 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87002.1 - 3.6e-06 27.2 0.0 1.5e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO87002.1 - 5.8e-06 25.5 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 GAO87002.1 - 0.0002 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 GAO87002.1 - 0.00053 19.6 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAO87002.1 - 0.0067 15.4 0.0 0.018 14.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 GAO87002.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Spo7_2_N PF15407.1 GAO87002.1 - 0.092 12.2 0.0 0.31 10.5 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein family 7 ADH_zinc_N PF00107.21 GAO87003.1 - 6.7e-26 90.3 0.1 1e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO87003.1 - 5.4e-22 77.6 2.0 9e-22 76.9 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO87003.1 - 3.9e-05 24.5 0.0 8.7e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF849 PF05853.7 GAO87003.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Arf PF00025.16 GAO87004.1 - 1.2e-73 246.0 0.0 1.4e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAO87004.1 - 4.3e-12 45.6 0.0 5.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAO87004.1 - 5.5e-10 38.8 0.0 6.5e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAO87004.1 - 6.8e-10 38.1 0.7 3.8e-06 25.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAO87004.1 - 5.9e-09 35.4 0.0 7.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO87004.1 - 1e-07 32.4 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAO87004.1 - 5.9e-06 26.2 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO87004.1 - 4.6e-05 22.9 0.0 0.0068 15.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAO87004.1 - 0.013 14.7 0.4 0.058 12.6 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Paf1 PF03985.8 GAO87005.1 - 8.7e-40 136.7 0.1 5.7e-38 130.7 0.1 3.0 1 1 0 1 1 1 1 Paf1 Actin PF00022.14 GAO87005.1 - 1.5e-28 99.3 0.0 9.5e-17 60.4 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 GAO87005.1 - 1.7e-05 23.6 0.0 0.012 14.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 GAO87005.1 - 0.23 9.7 0.1 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) DHO_dh PF01180.16 GAO87006.1 - 9.9e-63 211.8 0.0 7.2e-53 179.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 GAO87006.1 - 0.003 16.8 0.2 0.85 8.8 0.0 2.4 2 0 0 2 2 2 2 PcrB family TIM PF00121.13 GAO87007.1 - 1.5e-47 161.7 0.0 1.8e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Plasmod_MYXSPDY PF07981.6 GAO87007.1 - 0.075 12.7 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY LacAB_rpiB PF02502.13 GAO87008.1 - 1.3e-41 141.4 0.0 1.5e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 GAO87008.1 - 0.00072 19.4 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycine-rich SFCGS U-box PF04564.10 GAO87009.1 - 8.4e-22 76.9 0.0 1.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 GAO87009.1 - 1.1e-15 57.0 2.5 4.6e-14 51.8 0.1 2.6 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 GAO87009.1 - 1.3e-08 34.0 4.5 0.00015 21.4 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO87009.1 - 7.3e-07 29.4 3.9 0.03 14.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO87009.1 - 2.6e-06 27.9 4.4 0.00069 20.2 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO87009.1 - 1.4e-05 24.5 7.9 4.2e-05 22.9 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO87009.1 - 7e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAO87009.1 - 9.5e-05 22.7 4.5 0.059 14.0 0.0 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO87009.1 - 0.00024 20.9 1.1 0.52 10.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAO87009.1 - 0.00029 20.7 1.4 1.6 9.1 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat GvpG PF05120.7 GAO87009.1 - 0.0093 15.7 0.3 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 Gas vesicle protein G TPR_4 PF07721.9 GAO87009.1 - 0.022 15.1 0.1 0.11 13.0 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Mer2 PF09074.5 GAO87009.1 - 0.039 13.8 0.7 0.061 13.2 0.5 1.3 1 0 0 1 1 1 0 Mer2 TPR_7 PF13176.1 GAO87009.1 - 0.11 12.3 5.9 4.7 7.2 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO87009.1 - 0.18 12.3 1.3 2.8 8.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAO87009.1 - 0.49 10.2 2.0 0.98 9.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ACBP PF00887.14 GAO87010.1 - 1.5e-20 72.5 2.2 2.3e-20 72.0 1.6 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 GAO87011.1 - 3.9e-156 520.1 0.0 4.6e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 GAO87011.1 - 0.00046 19.9 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain DIE2_ALG10 PF04922.7 GAO87012.1 - 6.3e-77 259.1 16.8 8.8e-69 232.3 8.4 2.4 2 1 0 2 2 2 2 DIE2/ALG10 family Sld5 PF05916.6 GAO87013.1 - 1.7e-31 108.6 0.0 2.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Amelin PF05111.7 GAO87013.1 - 0.0049 15.6 3.4 0.0063 15.3 2.4 1.1 1 0 0 1 1 1 1 Ameloblastin precursor (Amelin) CUE PF02845.11 GAO87014.1 - 2.6e-12 45.9 0.0 4.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain Metal_resist PF13801.1 GAO87014.1 - 8.8 6.3 9.8 22 5.0 3.8 2.4 3 0 0 3 3 3 0 Heavy-metal resistance SMC_N PF02463.14 GAO87015.1 - 9e-68 227.7 9.4 5.8e-67 225.1 6.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAO87015.1 - 1.4e-23 83.1 1.0 2.2e-22 79.2 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAO87015.1 - 1e-14 55.1 2.9 8.9e-06 25.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAO87015.1 - 8e-05 22.0 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 GAO87015.1 - 0.0003 19.3 32.9 0.0003 19.3 22.8 5.5 3 2 2 5 5 5 3 AAA domain TMF_DNA_bd PF12329.3 GAO87015.1 - 0.0011 18.6 13.8 0.0011 18.6 9.6 11.5 5 2 6 12 12 12 1 TATA element modulatory factor 1 DNA binding GAS PF13851.1 GAO87015.1 - 0.0023 17.1 4.9 0.0023 17.1 3.4 7.5 3 2 2 6 6 6 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 GAO87015.1 - 0.0053 15.9 31.8 0.87 8.7 1.5 6.1 4 2 4 8 8 8 5 Reovirus sigma C capsid protein MscS_porin PF12795.2 GAO87015.1 - 0.0057 16.0 25.6 0.0057 16.0 17.7 7.1 2 2 5 7 7 7 1 Mechanosensitive ion channel porin domain AAA_23 PF13476.1 GAO87015.1 - 0.24 11.7 114.8 0.044 14.0 33.1 6.4 2 2 1 3 3 2 0 AAA domain IncA PF04156.9 GAO87015.1 - 5.5 6.5 123.2 0.075 12.6 12.1 6.7 4 2 2 7 7 7 0 IncA protein Ubie_methyltran PF01209.13 GAO87016.1 - 2.2e-15 56.3 0.0 3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAO87016.1 - 1.2e-11 44.9 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87016.1 - 2.6e-08 33.5 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87016.1 - 2.7e-08 34.1 0.0 4.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87016.1 - 4.6e-07 29.6 0.0 6.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87016.1 - 5.5e-07 29.8 0.0 9.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87016.1 - 6e-05 23.5 0.0 9.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87016.1 - 0.0004 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO87016.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NOT2_3_5 PF04153.13 GAO87017.1 - 5.8e-36 123.3 0.1 5.8e-36 123.3 0.0 2.4 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 GAO87018.1 - 8.4e-20 70.4 0.1 1.3e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF3876 PF12992.2 GAO87018.1 - 0.081 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) Clc-like PF07062.7 GAO87018.1 - 0.26 10.5 2.8 0.38 9.9 1.7 1.5 2 0 0 2 2 2 0 Clc-like GDI PF00996.13 GAO87019.1 - 3e-184 612.4 0.0 3.8e-184 612.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.22 GAO87019.1 - 0.091 13.1 0.3 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87019.1 - 0.092 12.7 0.1 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.17 GAO87020.1 - 7.8e-13 48.3 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAO87020.1 - 4.9e-05 23.2 0.1 9.6e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily ORC4_C PF14629.1 GAO87021.1 - 3.4e-57 193.1 0.0 1.2e-56 191.3 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 GAO87021.1 - 4.3e-17 62.6 0.3 5.4e-16 59.1 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 GAO87021.1 - 2.5e-07 30.9 0.2 1.5e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAO87021.1 - 4.5e-07 29.6 0.1 1.8e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 GAO87021.1 - 9e-06 24.7 0.2 1.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 GAO87021.1 - 9.7e-06 24.7 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 GAO87021.1 - 1.4e-05 25.2 0.0 3.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAO87021.1 - 1.7e-05 24.6 0.0 5.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 GAO87021.1 - 0.0025 17.7 0.1 0.025 14.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 GAO87021.1 - 0.0089 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 GAO87021.1 - 0.011 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Mg_chelatase PF01078.16 GAO87021.1 - 0.041 13.0 0.0 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 GAO87021.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAO87021.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 GAO87021.1 - 0.07 12.6 0.1 0.58 9.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.15 GAO87021.1 - 0.1 11.2 0.0 0.24 10.0 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit RGS PF00615.14 GAO87022.1 - 1.3e-34 118.8 0.1 3.1e-34 117.6 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 GAO87022.1 - 7.5e-27 92.8 0.0 5.7e-20 70.8 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 GAO87023.1 - 3.2e-41 141.5 0.3 5.3e-40 137.5 0.4 2.5 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family SET PF00856.23 GAO87025.1 - 6.6e-06 26.5 0.1 6.6e-06 26.5 0.1 2.8 2 1 0 2 2 2 1 SET domain PHD PF00628.24 GAO87025.1 - 7.2e-05 22.3 10.8 0.00014 21.4 7.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF3408 PF11888.3 GAO87025.1 - 0.15 11.9 0.1 0.15 11.9 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3408) AA_permease PF00324.16 GAO87026.1 - 1.5e-51 175.2 31.2 2e-51 174.8 21.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO87026.1 - 3.6e-22 78.4 31.9 4.5e-22 78.1 22.1 1.1 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 GAO87027.1 - 6.4e-22 76.5 12.0 1.8e-05 24.4 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 GAO87028.1 - 2.7e-32 111.7 12.2 2.7e-32 111.7 8.4 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 Aldo_ket_red PF00248.16 GAO87029.1 - 1.6e-66 224.0 0.1 1.8e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AHH PF14412.1 GAO87029.1 - 0.071 13.1 0.9 0.094 12.7 0.1 1.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Aconitase PF00330.15 GAO87030.1 - 3.2e-180 599.5 0.0 3.7e-180 599.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAO87030.1 - 9.5e-46 155.1 0.0 1.8e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Alpha-amylase PF00128.19 GAO87031.1 - 2.6e-18 66.5 1.2 1.3e-17 64.1 0.8 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 GAO87031.1 - 3.3e-15 56.2 0.1 5.8e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 GAO87031.1 - 3.7e-06 27.1 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAO87031.1 - 7.6e-06 25.4 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.22 GAO87032.1 - 3.6e-16 59.0 0.5 5.8e-16 58.3 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain MTHFR PF02219.12 GAO87033.1 - 1.4e-114 382.0 0.0 1.9e-114 381.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2418 PF10332.4 GAO87035.1 - 2e-37 127.4 1.5 4e-37 126.4 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 GAO87036.1 - 2.1e-30 104.9 0.0 2.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 GAO87037.1 - 7.6e-30 103.8 0.1 9.7e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 GAO87037.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.8 1 1 0 1 1 1 1 ML-like domain DUF4625 PF15418.1 GAO87037.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) CopC PF04234.7 GAO87037.1 - 0.16 12.6 0.0 0.33 11.5 0.0 1.6 1 1 0 1 1 1 0 CopC domain Thiolase_N PF00108.18 GAO87038.1 - 1.6e-68 230.5 1.9 1.6e-68 230.5 1.3 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO87038.1 - 5.2e-43 145.3 1.4 8.4e-43 144.7 0.2 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 GAO87038.1 - 0.0018 18.2 0.0 0.009 16.0 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAO87038.1 - 0.0041 16.7 1.3 0.03 13.9 0.2 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 GAO87038.1 - 0.0088 15.5 1.7 0.022 14.2 1.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF2803 PF10972.3 GAO87038.1 - 0.039 13.4 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) AMP-binding PF00501.23 GAO87039.1 - 3.5e-63 213.4 0.0 4.4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO87039.1 - 4.5e-06 27.5 0.0 1e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATG22 PF11700.3 GAO87040.1 - 5.4e-137 457.1 28.5 6.1e-137 456.9 19.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAO87040.1 - 2.7e-10 39.4 32.2 2.7e-05 23.0 0.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Zip PF02535.17 GAO87040.1 - 0.087 11.8 3.4 0.095 11.6 0.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter CT47 PF15623.1 GAO87041.1 - 0.013 15.2 14.8 0.02 14.6 10.2 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Methyltransf_23 PF13489.1 GAO87042.1 - 6.3e-06 25.9 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87042.1 - 1.6e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 GAO87042.1 - 0.0016 16.8 0.0 0.0021 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 GAO87042.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87042.1 - 0.034 14.6 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 GAO87042.1 - 0.045 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ribosomal_L31e PF01198.14 GAO87042.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31e Methyltransf_31 PF13847.1 GAO87042.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 GAO87043.1 - 9.1e-34 116.7 27.4 9.1e-34 116.7 19.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87043.1 - 2.6e-10 39.4 9.2 2.6e-10 39.4 6.3 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAO87043.1 - 5.3e-05 21.6 1.7 8.4e-05 20.9 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Spc97_Spc98 PF04130.8 GAO87044.1 - 3.5e-138 461.3 3.8 3.5e-138 461.3 2.7 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family HECT_2 PF09814.4 GAO87044.1 - 0.069 11.8 3.5 0.12 11.0 2.4 1.3 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TAF4 PF05236.9 GAO87044.1 - 4.1 6.5 14.6 9.5 5.3 10.2 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Proteasome PF00227.21 GAO87045.1 - 1.4e-56 190.8 0.0 1.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAO87045.1 - 9.6e-14 50.3 0.2 2.4e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_8 PF05148.10 GAO87046.1 - 9.6e-53 179.0 0.0 1.2e-50 172.1 0.0 2.8 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 GAO87046.1 - 1.9e-07 31.4 0.0 7.4e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87046.1 - 0.0078 16.5 0.0 0.34 11.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAO87046.1 - 0.048 13.3 0.3 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans_2 PF11951.3 GAO87047.1 - 1.1e-15 57.2 0.8 8.6e-12 44.3 0.8 3.0 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87047.1 - 8.1e-07 28.8 10.7 1.4e-06 28.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO87047.1 - 0.1 11.4 0.3 0.18 10.6 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain BAR_2 PF10455.4 GAO87049.1 - 2.6e-62 210.3 0.2 3.8e-62 209.8 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 GAO87049.1 - 2.1e-20 73.2 3.9 1.9e-19 70.1 2.7 1.9 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 GAO87049.1 - 0.27 11.0 6.2 0.087 12.6 1.1 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Arv1 PF04161.8 GAO87050.1 - 4.3e-39 134.6 0.0 8.1e-34 117.3 0.0 2.1 2 0 0 2 2 2 2 Arv1-like family DUF605 PF04652.11 GAO87050.1 - 7 5.9 11.2 9.2 5.5 7.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF619 PF04768.8 GAO87051.1 - 1.3e-53 180.8 0.0 5.4e-53 178.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Integrase_AP2 PF14657.1 GAO87051.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain Acetyltransf_1 PF00583.19 GAO87052.1 - 2.9e-11 43.2 0.0 5.9e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO87052.1 - 4.9e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO87052.1 - 9e-05 22.3 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO87052.1 - 0.003 17.6 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO87052.1 - 0.0079 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAO87052.1 - 0.042 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 GAO87052.1 - 0.074 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NOGCT PF08155.6 GAO87053.1 - 6.8e-31 105.7 4.5 1.5e-30 104.6 3.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 GAO87053.1 - 5.9e-27 93.3 0.5 1.3e-26 92.1 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 GAO87053.1 - 5.7e-15 55.2 0.0 1.4e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO87053.1 - 5.6e-07 28.9 0.0 1.3e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 GAO87053.1 - 3.9e-05 24.1 0.0 0.00037 20.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 GAO87053.1 - 0.025 14.4 0.0 7 6.4 0.0 2.7 1 1 1 2 2 2 0 Dynamin family Sigma54_activ_2 PF14532.1 GAO87053.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sugar_tr PF00083.19 GAO87054.1 - 1.2e-136 455.8 30.5 1.4e-136 455.6 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO87054.1 - 3.7e-22 78.5 52.3 8.7e-20 70.7 20.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAO87054.1 - 0.15 12.0 3.7 0.084 12.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) adh_short PF00106.20 GAO87055.1 - 1.8e-21 76.7 0.4 3e-21 76.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87055.1 - 1.7e-09 37.7 0.0 2.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87055.1 - 0.00011 21.9 0.1 0.00023 20.8 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO87055.1 - 0.0055 16.7 0.3 0.012 15.6 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO87055.1 - 0.038 12.8 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.8 GAO87056.1 - 7.8e-43 145.0 0.6 9.4e-43 144.7 0.4 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 GAO87057.1 - 5.3e-69 231.9 0.1 5.3e-67 225.4 0.0 2.5 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 GAO87057.1 - 5.3e-57 192.0 0.8 8e-57 191.4 0.2 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 GAO87057.1 - 0.11 13.0 0.0 0.58 10.7 0.0 2.1 2 1 0 2 2 2 0 HIT domain F-box-like PF12937.2 GAO87058.1 - 7.6e-05 22.3 0.3 0.00015 21.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO87058.1 - 0.0029 17.2 0.3 0.0059 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 GAO87059.1 - 6.5e-44 150.0 42.4 6.5e-44 150.0 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87059.1 - 1.2e-12 47.1 19.1 2.4e-12 46.1 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter UDPGT PF00201.13 GAO87060.1 - 3.7e-08 32.3 0.0 4.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NAD_binding_2 PF03446.10 GAO87061.1 - 1.9e-32 112.3 0.1 3.1e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAO87061.1 - 2e-11 44.0 0.1 3.7e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAO87061.1 - 4.5e-10 39.8 0.3 1.2e-09 38.4 0.1 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAO87061.1 - 3.7e-08 33.5 0.0 5.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 GAO87061.1 - 0.0047 15.7 0.2 0.0061 15.3 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 GAO87061.1 - 0.0047 17.4 0.0 0.025 15.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 GAO87061.1 - 0.019 14.3 0.1 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ldh_1_N PF00056.18 GAO87061.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAO87061.1 - 0.036 13.4 0.5 0.16 11.3 0.4 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 GAO87061.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAO87061.1 - 0.11 12.1 0.2 0.38 10.3 0.2 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO87061.1 - 0.11 12.2 0.4 0.21 11.3 0.2 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Alpha-amylase PF00128.19 GAO87062.1 - 1.3e-98 330.2 0.3 2e-98 329.7 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAO87062.1 - 0.00084 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase PF00128.19 GAO87063.1 - 1.8e-80 270.6 0.0 1.1e-39 136.7 0.1 2.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CoA_binding_2 PF13380.1 GAO87066.1 - 4.1e-27 94.6 0.0 4.9e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Legionella_OMP PF05150.7 GAO87066.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Rad4 PF03835.10 GAO87067.1 - 8.3e-40 135.5 0.3 8.3e-40 135.5 0.2 2.2 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAO87067.1 - 3.5e-30 103.5 0.1 5.8e-30 102.8 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 GAO87067.1 - 8.5e-20 70.8 0.4 1.2e-18 67.1 0.0 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 GAO87067.1 - 5.7e-17 60.9 0.0 1.4e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 GAO87067.1 - 0.012 15.8 0.0 0.045 13.9 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily HAUS6_N PF14661.1 GAO87068.1 - 1.6e-49 168.5 0.8 3.5e-49 167.3 0.0 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 GAO87069.1 - 1.1e-47 161.8 0.2 1.3e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 GAO87069.1 - 0.019 14.7 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HIT PF01230.18 GAO87070.1 - 1e-23 83.6 0.1 1.9e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAO87070.1 - 7.9e-06 26.0 0.1 1.2e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DGF-1_4 PF11024.3 GAO87070.1 - 0.046 14.1 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 GalP_UDP_tr_C PF02744.12 GAO87070.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Mob1_phocein PF03637.12 GAO87071.1 - 2.1e-26 92.6 0.0 4.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 GAO87072.1 - 7.2e-45 152.6 0.1 9.5e-45 152.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAO87072.1 - 2.2e-05 24.0 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Septin PF00735.13 GAO87072.1 - 0.0029 16.6 0.2 0.54 9.2 0.0 2.2 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 GAO87072.1 - 0.0029 17.3 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAO87072.1 - 0.0033 17.4 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO87072.1 - 0.0056 16.8 0.1 0.093 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO87072.1 - 0.0068 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAO87072.1 - 0.014 14.3 0.1 0.028 13.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAO87072.1 - 0.017 15.0 0.1 0.048 13.6 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArgK PF03308.11 GAO87072.1 - 0.02 13.6 0.4 1.3 7.7 0.0 2.6 3 0 0 3 3 3 0 ArgK protein AAA_19 PF13245.1 GAO87072.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF1827 PF08860.5 GAO87072.1 - 0.051 13.6 0.2 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) AAA_29 PF13555.1 GAO87072.1 - 0.062 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 GAO87072.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 GAO87072.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAO87072.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 GAO87072.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 GAO87072.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAO87072.1 - 0.11 12.8 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 GAO87072.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 GAO87073.1 - 3.8e-13 49.2 0.0 1.6e-11 43.8 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87073.1 - 1.6e-12 47.0 0.0 1.3e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 GAO87074.1 - 2.5e-63 213.1 0.0 4.6e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAO87074.1 - 6.3e-36 123.9 0.0 1.3e-35 122.9 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAO87074.1 - 7.3e-22 77.9 0.0 1.7e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAO87074.1 - 1.8e-07 30.9 0.0 3.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 GAO87074.1 - 1.6e-06 27.6 0.0 4.9e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 GAO87074.1 - 3.2e-06 27.1 0.0 9.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 GAO87074.1 - 6.4e-06 25.0 0.0 1.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 GAO87074.1 - 8.1e-06 26.0 0.1 0.00016 21.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO87074.1 - 6.5e-05 23.7 0.0 0.00027 21.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO87074.1 - 7.5e-05 22.7 0.0 0.00037 20.5 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAO87074.1 - 0.0003 19.9 0.0 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAO87074.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO87074.1 - 0.005 17.1 1.3 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 GAO87074.1 - 0.0057 16.5 0.6 0.0057 16.5 0.4 2.7 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein IstB_IS21 PF01695.12 GAO87074.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 GAO87074.1 - 0.027 13.9 0.0 0.085 12.3 0.0 1.9 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 GAO87074.1 - 0.034 13.8 0.2 0.36 10.5 0.0 2.5 1 1 1 2 2 2 0 NTPase DUF258 PF03193.11 GAO87074.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAO87074.1 - 0.059 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 GAO87074.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAO87074.1 - 0.092 12.5 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 GAO87074.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAO87074.1 - 0.15 12.3 1.5 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 GAO87074.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CTDII PF01556.13 GAO87075.1 - 1.7e-29 101.5 1.1 2.9e-21 75.1 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 GAO87075.1 - 5e-24 83.8 3.0 1e-23 82.7 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAO87075.1 - 2.6e-11 43.3 19.1 4.8e-11 42.5 13.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAO87075.1 - 3.6 7.2 8.2 2.9 7.6 0.5 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family BRO1 PF03097.13 GAO87076.1 - 3.1e-132 440.8 7.0 3.1e-132 440.8 4.8 2.9 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAO87076.1 - 2.4e-99 332.0 14.3 2.4e-99 332.0 9.9 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV SAP30_Sin3_bdg PF13867.1 GAO87077.1 - 2e-15 56.3 0.3 8.5e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4466 PF14725.1 GAO87077.1 - 0.0061 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4466) DUF3114 PF11311.3 GAO87077.1 - 0.047 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) zf-H2C2_2 PF13465.1 GAO87078.1 - 1.9e-09 37.3 17.9 1.1e-05 25.4 2.3 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAO87078.1 - 6.3e-08 32.5 13.4 0.0014 18.8 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO87078.1 - 0.012 15.8 22.2 0.013 15.7 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO87078.1 - 0.56 10.4 2.5 0.4 10.8 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 GAO87079.1 - 0.055 13.7 1.3 0.055 13.7 0.9 2.0 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 GAO87079.1 - 0.3 11.4 2.1 1.9 8.9 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO87079.1 - 1.2 9.5 12.7 0.55 10.6 0.2 4.1 4 1 1 5 5 5 0 C2H2-type zinc finger LSM PF01423.17 GAO87080.1 - 1.6e-13 49.9 0.1 3.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.7 GAO87081.1 - 1.4e-77 259.5 0.1 5.8e-77 257.5 0.0 2.1 2 0 0 2 2 2 1 NUC173 domain HEAT_2 PF13646.1 GAO87081.1 - 0.0084 16.3 0.8 1.3 9.3 0.1 4.1 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 GAO87081.1 - 0.019 15.0 1.7 4 7.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat YL1 PF05764.8 GAO87081.1 - 0.12 11.9 6.6 0.29 10.7 4.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein TPR_1 PF00515.23 GAO87083.1 - 7.2e-52 170.9 27.0 4.2e-08 32.4 0.0 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAO87083.1 - 2.3e-47 155.0 17.2 1.3e-05 24.7 0.0 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 GAO87083.1 - 5e-44 147.8 20.6 2.7e-10 39.7 0.7 6.4 2 2 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 GAO87083.1 - 1.1e-40 134.4 19.4 2.6e-05 23.6 0.6 10.3 8 1 2 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.1 GAO87083.1 - 3.3e-30 103.8 21.6 7.5e-08 32.2 0.3 7.5 3 2 4 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAO87083.1 - 5.3e-30 103.4 13.9 5.9e-07 29.9 0.1 6.8 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAO87083.1 - 6.9e-26 88.3 14.6 7.9e-05 22.9 0.0 10.0 3 2 8 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.1 GAO87083.1 - 1.2e-25 87.4 18.2 0.00068 19.6 0.0 10.1 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAO87083.1 - 4e-22 78.3 14.5 8.3e-05 22.8 0.0 7.3 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAO87083.1 - 2.6e-21 73.6 12.1 0.0049 16.5 0.0 9.9 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAO87083.1 - 1.8e-20 71.9 18.0 0.0059 16.9 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAO87083.1 - 4.1e-15 55.3 8.4 0.0026 17.5 0.0 6.9 3 2 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO87083.1 - 1.3e-12 47.6 10.5 1.7e-08 34.4 1.4 4.1 3 1 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAO87083.1 - 1.2e-07 31.0 10.4 0.0012 17.9 1.6 4.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 GAO87083.1 - 0.0001 22.3 9.6 0.33 10.9 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 GAO87083.1 - 0.0021 17.5 4.7 0.71 9.2 0.0 3.1 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.1 GAO87083.1 - 0.0032 17.5 0.2 0.87 9.7 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 GAO87083.1 - 0.011 16.0 4.9 2 8.7 0.0 3.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 GAO87083.1 - 0.045 13.6 8.5 19 5.3 0.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 GAO87083.1 - 2.6 8.0 20.0 2.1 8.3 1.3 5.5 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.17 GAO87084.1 - 2.4e-120 400.8 9.3 3e-120 400.5 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 ESAG1 PF03238.8 GAO87084.1 - 0.071 12.4 0.1 0.44 9.7 0.1 1.9 2 0 0 2 2 2 0 ESAG protein NuiA PF07924.6 GAO87085.1 - 8.9e-05 22.4 0.8 0.0093 15.8 0.0 2.4 3 0 0 3 3 3 2 Nuclease A inhibitor-like protein SKN1 PF03935.10 GAO87086.1 - 7.4e-233 773.2 0.8 8.6e-233 773.0 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 GAO87086.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Neurensin BCDHK_Adom3 PF10436.4 GAO87088.1 - 5.8e-71 237.2 0.0 8e-71 236.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAO87088.1 - 2.1e-17 62.8 0.0 4.8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAO87088.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lyase_1 PF00206.15 GAO87090.1 - 5.7e-21 75.0 0.0 9.2e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 GAO87090.1 - 5.1e-16 58.4 0.0 1.6e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Exo70 PF03081.10 GAO87091.1 - 4.2e-79 266.0 0.0 4.8e-78 262.5 0.0 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit TPD52 PF04201.10 GAO87091.1 - 0.03 14.0 0.1 0.085 12.5 0.1 1.7 1 0 0 1 1 1 0 Tumour protein D52 family NPV_P10 PF05531.7 GAO87091.1 - 0.78 10.0 3.2 15 5.9 0.0 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Streptin-Immun PF11083.3 GAO87091.1 - 1.4 8.9 4.3 63 3.6 0.2 3.4 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein PLA2_B PF01735.13 GAO87092.1 - 5e-26 90.9 0.0 1.4e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.15 GAO87093.1 - 3.3e-10 39.6 0.0 6.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAO87093.1 - 0.00016 21.0 0.0 0.00039 19.8 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAO87093.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PPR_2 PF13041.1 GAO87095.1 - 9.4e-19 67.1 0.5 0.0011 18.8 0.0 6.2 4 3 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 GAO87095.1 - 2.4e-16 58.5 4.0 0.00028 20.9 0.0 8.7 9 2 1 10 10 10 3 Pentatricopeptide repeat domain PPR PF01535.15 GAO87095.1 - 1.8e-07 30.6 5.8 0.72 9.9 0.0 6.3 6 0 0 6 6 6 3 PPR repeat PET122 PF05476.6 GAO87095.1 - 0.00046 19.5 0.4 0.00072 18.8 0.3 1.4 1 0 0 1 1 1 1 PET122 Phage_term_smal PF05944.7 GAO87095.1 - 0.0064 16.1 0.1 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 Phage small terminase subunit TPR_16 PF13432.1 GAO87095.1 - 0.025 15.2 1.5 0.56 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO87095.1 - 0.037 14.6 1.1 4.9 8.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 GAO87095.1 - 0.082 12.3 0.0 37 3.9 0.0 4.1 4 0 0 4 4 4 0 PPR repeat LSM PF01423.17 GAO87096.1 - 6.6e-17 60.8 0.0 1.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAO87096.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.5 1 1 1 2 2 2 0 Ataxin 2 SM domain API5 PF05918.6 GAO87096.1 - 4.9 5.5 10.5 6.1 5.2 7.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Hat1_N PF10394.4 GAO87097.1 - 4.9e-48 163.2 0.2 1.2e-47 161.9 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 GAO87097.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IncA PF04156.9 GAO87097.1 - 0.062 12.9 1.0 0.091 12.3 0.7 1.2 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 GAO87098.1 - 6.4e-38 130.5 15.4 1.5e-28 99.7 5.3 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3649 PF12365.3 GAO87098.1 - 0.97 8.9 5.9 1.9 8.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) WD40 PF00400.27 GAO87099.1 - 4.3e-51 169.0 18.4 4.7e-09 35.7 0.5 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 GAO87099.1 - 9.6e-11 41.2 0.7 2.2e-10 40.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 GAO87099.1 - 2.6e-09 35.7 8.0 0.0014 16.8 0.2 5.2 1 1 4 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 GAO87099.1 - 0.00024 20.6 0.6 0.00052 19.6 0.4 1.6 1 0 0 1 1 1 1 F-box domain Nuc_N PF14448.1 GAO87099.1 - 0.61 9.6 3.1 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 Nuclease N terminal Lamp PF01299.12 GAO87099.1 - 1.8 7.6 3.9 2.8 6.9 2.7 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Zn_clus PF00172.13 GAO87100.1 - 1.2e-06 28.2 4.4 1.2e-06 28.2 3.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydrat_N PF13452.1 GAO87100.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Mito_carr PF00153.22 GAO87101.1 - 1.7e-45 152.6 3.0 3.1e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.9 GAO87103.1 - 6.9e-54 182.3 0.1 1.1e-53 181.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.6 GAO87104.1 - 9.8e-23 80.2 3.9 9.8e-23 80.2 2.7 3.8 3 2 0 3 3 3 1 U3 snoRNA associated Mitofilin PF09731.4 GAO87104.1 - 0.088 11.4 27.3 0.021 13.5 16.9 1.5 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CTK3 PF12243.3 GAO87105.1 - 1.4e-60 202.9 0.3 1.8e-60 202.5 0.2 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 GAO87105.1 - 1.9e-21 75.8 4.1 5.8e-21 74.2 2.8 1.9 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Pox_VLTF3 PF04947.9 GAO87105.1 - 0.013 15.0 0.2 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like MAM33 PF02330.11 GAO87105.1 - 0.024 14.4 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial glycoprotein Voltage_CLC PF00654.15 GAO87106.1 - 5.2e-82 275.7 24.4 5.2e-82 275.7 16.9 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAO87106.1 - 8.8e-05 22.2 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.9 GAO87107.1 - 5.3e-130 427.9 0.8 2.1e-22 79.3 0.0 9.9 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 GAO87107.1 - 2.4e-30 105.4 1.0 9.1e-05 22.6 0.0 8.0 8 0 0 8 8 7 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 GAO87107.1 - 3.4e-29 101.0 0.0 6.9e-11 41.8 0.0 7.2 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAO87107.1 - 4.4e-25 88.2 0.0 0.002 17.9 0.0 7.4 6 1 0 6 6 6 5 AAA domain AAA_22 PF13401.1 GAO87107.1 - 2.5e-21 76.1 0.4 0.017 15.2 0.0 8.7 8 0 0 8 8 6 4 AAA domain AAA_17 PF13207.1 GAO87107.1 - 2.1e-20 73.7 0.0 0.0015 19.3 0.0 7.5 6 0 0 6 6 6 4 AAA domain AAA_16 PF13191.1 GAO87107.1 - 3e-20 72.9 19.6 0.0011 19.0 0.1 9.3 8 0 0 8 8 7 5 AAA ATPase domain AAA_14 PF13173.1 GAO87107.1 - 1.4e-19 70.2 0.0 0.0007 19.4 0.0 7.5 8 0 0 8 8 6 3 AAA domain AAA_18 PF13238.1 GAO87107.1 - 7.1e-17 61.9 3.8 0.0062 16.8 0.0 7.3 7 0 0 7 7 6 4 AAA domain ABC_tran PF00005.22 GAO87107.1 - 1.5e-15 57.7 0.2 0.031 14.5 0.0 6.7 6 0 0 6 6 6 3 ABC transporter Zeta_toxin PF06414.7 GAO87107.1 - 2.7e-15 56.0 0.6 0.17 10.9 0.0 8.2 9 0 0 9 9 8 3 Zeta toxin Sigma54_activat PF00158.21 GAO87107.1 - 2.7e-15 56.2 0.0 0.0052 16.2 0.1 6.2 6 0 0 6 6 6 3 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 GAO87107.1 - 6.5e-14 52.1 0.5 0.0004 20.4 0.1 6.2 6 0 0 6 6 5 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 GAO87107.1 - 7.6e-13 48.7 0.0 0.013 15.1 0.0 6.4 6 0 0 6 6 6 1 Archaeal ATPase UPF0079 PF02367.12 GAO87107.1 - 8.3e-13 48.0 4.3 0.1 12.2 0.2 6.4 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 GAO87107.1 - 9.9e-13 48.2 0.8 0.57 10.3 0.0 6.8 6 0 0 6 6 6 2 RNA helicase MobB PF03205.9 GAO87107.1 - 2.7e-12 46.6 2.6 0.37 10.4 0.0 6.7 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAO87107.1 - 4.7e-12 45.8 7.1 0.055 13.1 0.1 6.3 6 0 0 6 6 5 4 NACHT domain Mg_chelatase PF01078.16 GAO87107.1 - 8e-12 44.7 2.5 5.7 6.0 0.0 8.8 9 1 0 9 9 9 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAO87107.1 - 8.3e-12 44.7 5.0 0.071 12.8 0.1 6.5 6 0 0 6 6 6 2 Part of AAA domain SRP54 PF00448.17 GAO87107.1 - 2.1e-11 43.6 2.3 0.095 12.1 0.1 5.9 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 GAO87107.1 - 5.1e-11 42.8 6.8 0.25 11.3 0.1 7.6 7 0 0 7 7 6 2 AAA domain T2SE PF00437.15 GAO87107.1 - 8.8e-11 41.2 0.3 0.3 9.9 0.1 6.1 6 0 0 6 6 5 2 Type II/IV secretion system protein AAA_25 PF13481.1 GAO87107.1 - 1.3e-10 40.9 1.6 0.4 10.0 0.0 6.0 5 0 0 5 5 5 3 AAA domain Miro PF08477.8 GAO87107.1 - 2e-10 41.2 3.1 0.81 10.2 0.0 6.9 6 0 0 6 6 6 1 Miro-like protein AAA_29 PF13555.1 GAO87107.1 - 6.2e-10 38.4 0.1 1.4 8.5 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain RuvB_N PF05496.7 GAO87107.1 - 9.2e-10 37.9 8.0 0.36 9.8 0.0 6.6 7 0 0 7 7 7 3 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 GAO87107.1 - 2.4e-09 36.5 3.1 0.14 11.3 0.1 6.0 6 0 0 6 6 6 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 GAO87107.1 - 2.9e-09 36.5 5.1 0.11 11.9 0.0 6.1 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAO87107.1 - 1.9e-08 34.2 0.7 0.17 11.8 0.0 6.5 6 0 0 6 6 6 1 50S ribosome-binding GTPase DUF815 PF05673.8 GAO87107.1 - 1.2e-07 30.8 2.5 0.16 10.8 0.1 5.2 6 0 0 6 6 5 2 Protein of unknown function (DUF815) NTPase_1 PF03266.10 GAO87107.1 - 1.8e-07 30.9 5.9 0.77 9.4 0.0 5.6 5 0 0 5 5 5 2 NTPase IstB_IS21 PF01695.12 GAO87107.1 - 2.5e-07 30.2 0.2 2.3 7.5 0.0 5.3 5 0 0 5 5 5 1 IstB-like ATP binding protein ATP_bind_1 PF03029.12 GAO87107.1 - 1.8e-06 27.6 1.9 0.86 9.0 0.0 5.4 5 0 0 5 5 5 2 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 GAO87107.1 - 3.3e-06 26.9 0.0 0.25 10.9 0.0 3.9 4 0 0 4 4 3 2 Bacterial dnaA protein SRPRB PF09439.5 GAO87107.1 - 1.4e-05 24.4 1.4 4.8 6.3 0.0 5.8 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit cobW PF02492.14 GAO87107.1 - 1.8e-05 24.2 5.2 7.5 5.9 0.1 6.2 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.2 GAO87107.1 - 2.7e-05 23.4 1.9 1.4 7.9 0.0 4.5 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 Rad17 PF03215.10 GAO87107.1 - 0.00026 19.8 1.4 2.5 6.6 0.0 4.7 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 GAO87107.1 - 0.00026 20.5 0.1 12 5.3 0.0 4.9 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 GAO87107.1 - 0.00031 20.3 0.2 16 4.9 0.0 5.3 6 0 0 6 6 4 0 AAA domain NB-ARC PF00931.17 GAO87107.1 - 0.0004 19.3 0.3 7.2 5.3 0.0 4.8 5 0 0 5 5 5 0 NB-ARC domain KTI12 PF08433.5 GAO87107.1 - 0.00043 19.5 0.4 1.2 8.3 0.0 4.3 4 0 0 4 4 4 1 Chromatin associated protein KTI12 ResIII PF04851.10 GAO87107.1 - 0.002 17.9 8.0 0.24 11.2 0.0 4.5 6 0 0 6 6 3 1 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 GAO87107.1 - 0.0064 16.0 0.0 25 4.2 0.0 3.9 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 GAO87107.1 - 0.0065 15.6 0.2 43 3.1 0.0 4.7 5 0 0 5 5 4 0 KaiC CbiA PF01656.18 GAO87107.1 - 0.008 15.6 0.4 0.52 9.6 0.1 3.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 GAO87107.1 - 0.012 14.8 0.3 4.6 6.4 0.0 3.8 4 0 0 4 4 4 0 PhoH-like protein FeoB_N PF02421.13 GAO87107.1 - 0.023 13.9 6.0 1.1 8.5 0.0 4.9 6 0 0 6 6 5 0 Ferrous iron transport protein B AAA_6 PF12774.2 GAO87107.1 - 0.025 14.1 0.0 27 4.1 0.0 4.4 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 ArgK PF03308.11 GAO87107.1 - 0.11 11.2 4.3 2.4 6.8 0.1 3.5 4 0 0 4 4 4 0 ArgK protein TIP49 PF06068.8 GAO87107.1 - 0.13 10.9 7.7 1.2 7.7 0.0 4.9 6 0 0 6 6 5 0 TIP49 C-terminus AAA_21 PF13304.1 GAO87107.1 - 0.19 11.6 0.0 12 5.7 0.0 3.9 5 0 0 5 5 3 0 AAA domain AAA_15 PF13175.1 GAO87107.1 - 0.56 9.1 0.0 66 2.3 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain PRCC PF10253.4 GAO87108.1 - 8.3e-45 153.7 1.4 8.3e-45 153.7 0.9 3.2 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting ORC3_N PF07034.6 GAO87109.1 - 0.1 11.5 0.7 0.17 10.8 0.5 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Lectin_leg-like PF03388.8 GAO87110.1 - 3e-66 222.8 0.0 3.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 GAO87110.1 - 0.013 14.9 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain zf-Tim10_DDP PF02953.10 GAO87111.1 - 1.1e-21 75.8 0.2 1.5e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ins_beta PF03488.9 GAO87111.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Pkinase PF00069.20 GAO87112.1 - 8.4e-69 231.6 0.1 1.9e-68 230.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87112.1 - 3.7e-37 127.8 0.0 7.3e-37 126.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87112.1 - 2e-06 26.9 0.0 4.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SIN1 PF05422.7 GAO87113.1 - 2.1e-36 125.5 10.5 4e-22 78.4 6.1 2.3 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) PH PF00169.24 GAO87113.1 - 0.026 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 PH domain TUG-UBL1 PF11470.3 GAO87113.1 - 0.035 14.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Nucleo_P87 PF07267.6 GAO87113.1 - 0.052 12.2 4.8 0.077 11.6 1.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RFC1 PF08519.7 GAO87114.1 - 2.7e-59 199.3 0.0 4.3e-58 195.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 GAO87114.1 - 5e-14 52.2 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 GAO87114.1 - 1.1e-09 38.6 0.0 2.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO87114.1 - 6.6e-08 32.7 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO87114.1 - 3.2e-05 24.7 0.3 0.00015 22.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 GAO87114.1 - 0.00038 19.2 0.0 0.00084 18.1 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 GAO87114.1 - 0.00069 19.5 0.1 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO87114.1 - 0.0013 18.4 0.3 0.0049 16.5 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 GAO87114.1 - 0.0016 18.4 0.0 0.015 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAO87114.1 - 0.003 16.6 0.0 0.0072 15.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAO87114.1 - 0.0068 16.7 2.4 0.01 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAO87114.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAO87114.1 - 0.024 14.6 0.0 0.068 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAO87114.1 - 0.025 14.2 0.0 0.19 11.3 0.0 2.2 1 1 0 1 1 1 0 NACHT domain DNA_pol3_delta PF06144.8 GAO87114.1 - 0.03 13.8 0.0 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PTCB-BRCT PF12738.2 GAO87114.1 - 0.051 13.4 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain AAA_5 PF07728.9 GAO87114.1 - 0.069 12.8 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAO87114.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_L16 PF00252.13 GAO87115.1 - 3.1e-29 101.4 0.1 3.8e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 GAO87116.1 - 5e-23 80.9 0.0 1.3e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAO87116.1 - 7.3e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAO87116.1 - 2.7e-06 27.6 0.2 6.6e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO87116.1 - 0.00031 20.8 0.6 0.0013 18.8 0.3 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO87116.1 - 0.0035 17.3 2.5 0.25 11.2 0.8 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAO87116.1 - 0.0074 16.1 0.1 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 GAO87116.1 - 0.013 15.5 0.3 0.33 10.9 0.2 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain SNF2_N PF00176.18 GAO87116.1 - 0.042 12.6 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 GAO87116.1 - 0.065 12.6 0.2 1.9 7.8 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 GAO87116.1 - 0.083 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 GAO87116.1 - 0.13 11.4 0.0 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAO87116.1 - 0.18 11.5 1.0 0.96 9.1 0.7 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CtaG_Cox11 PF04442.9 GAO87117.1 - 3.7e-58 195.6 0.0 4.7e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 HET PF06985.6 GAO87118.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HLH PF00010.21 GAO87119.1 - 7.3e-07 28.7 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Adeno_VII PF03228.9 GAO87119.1 - 0.19 12.3 3.1 0.19 12.2 1.1 1.7 1 1 0 1 1 1 0 Adenoviral core protein VII ORC6 PF05460.8 GAO87119.1 - 0.21 10.6 8.8 0.37 9.8 6.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-Q PF13094.1 GAO87120.1 - 1.3e-48 164.9 9.6 2e-48 164.4 6.7 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin PF00261.15 GAO87120.1 - 0.009 15.1 7.5 0.009 15.1 5.2 2.0 2 0 0 2 2 2 1 Tropomyosin Tropomyosin_1 PF12718.2 GAO87120.1 - 0.01 15.6 8.9 0.028 14.2 6.2 1.7 1 0 0 1 1 1 0 Tropomyosin like GET2 PF08690.5 GAO87120.1 - 0.19 10.9 1.6 0.31 10.2 1.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 TBPIP PF07106.8 GAO87120.1 - 0.32 10.5 8.3 13 5.2 0.0 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4164 PF13747.1 GAO87120.1 - 2 8.5 10.6 2.1 8.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) COG2 PF06148.6 GAO87120.1 - 2.1 8.2 8.1 0.42 10.4 1.0 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 GAO87120.1 - 6.7 5.5 10.6 3.1 6.6 5.6 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC-167 PF15188.1 GAO87120.1 - 8 6.4 9.5 12 5.9 4.9 2.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 SPO22 PF08631.5 GAO87121.1 - 1.3e-26 93.3 1.0 1.6e-21 76.6 0.4 2.5 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like WD40 PF00400.27 GAO87122.1 - 5.1e-32 108.5 6.0 1.5e-05 24.7 0.1 9.2 8 1 0 8 8 8 7 WD domain, G-beta repeat Sec23_trunk PF04811.10 GAO87122.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Neugrin PF06413.6 GAO87123.1 - 4.8e-14 52.7 0.4 4.8e-14 52.7 0.3 1.9 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 GAO87123.1 - 2.7e-05 24.1 9.8 5e-05 23.3 6.7 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Rgp1 PF08737.5 GAO87124.1 - 1.6e-111 373.3 0.0 5.3e-110 368.3 0.0 2.6 2 1 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 GAO87124.1 - 0.00027 20.7 0.0 0.00086 19.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAO87124.1 - 0.076 13.1 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 GAO87124.1 - 0.21 10.8 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.12 GAO87125.1 - 1.2e-71 240.0 0.0 1.5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 GAO87126.1 - 2.3e-45 154.5 2.4 2.6e-45 154.3 1.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1539 PF07560.6 GAO87126.1 - 0.45 10.3 2.2 3.4 7.5 0.3 2.3 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Glyco_hydro_63 PF03200.11 GAO87127.1 - 3.3e-06 25.2 6.8 7.8e-05 20.7 0.2 3.8 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase ADIP PF11559.3 GAO87128.1 - 0.0066 16.3 0.7 0.0093 15.8 0.5 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding AKNA PF12443.3 GAO87128.1 - 0.021 14.8 1.4 0.39 10.7 1.0 2.2 1 1 0 1 1 1 0 AT-hook-containing transcription factor Rab5-bind PF09311.6 GAO87128.1 - 0.034 14.0 0.5 0.043 13.7 0.4 1.2 1 0 0 1 1 1 0 Rabaptin-like protein RIC3 PF15361.1 GAO87128.1 - 0.055 13.7 0.4 0.055 13.7 0.3 1.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 YgaB PF14182.1 GAO87128.1 - 0.067 13.4 1.2 0.099 12.8 0.8 1.2 1 0 0 1 1 1 0 YgaB-like protein DUF2730 PF10805.3 GAO87128.1 - 0.13 11.9 0.7 1.9 8.2 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Bromodomain PF00439.20 GAO87129.1 - 1.9e-15 56.5 0.0 6.4e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Diphthamide_syn PF01866.12 GAO87130.1 - 4.5e-113 377.5 0.0 5.4e-113 377.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 GAO87131.1 - 1.2e-40 139.7 0.0 2e-40 138.9 0.0 1.4 1 1 0 1 1 1 1 HMGL-like Hce2 PF14856.1 GAO87132.1 - 4.8e-32 109.7 0.4 6.4e-32 109.3 0.2 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF1674 PF07896.7 GAO87133.1 - 9.4e-17 60.9 3.4 1.6e-16 60.2 2.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.16 GAO87134.1 - 6.6e-97 324.3 0.0 8.3e-97 324.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAO87134.1 - 5.3e-05 22.3 0.0 8.4e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II CLN3 PF02487.12 GAO87135.1 - 4.4e-94 315.5 9.1 3.5e-92 309.2 6.3 2.3 1 1 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.8 GAO87135.1 - 7.6e-35 120.3 0.1 2e-24 86.3 0.0 2.7 2 1 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO87135.1 - 0.00033 19.3 0.0 0.00085 18.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Lipase_3 PF01764.20 GAO87135.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.11 GAO87136.1 - 1.1e-39 136.2 42.0 1.1e-39 136.2 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rxt3 PF08642.5 GAO87138.1 - 2.2e-30 105.2 0.0 5.9e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 GAO87138.1 - 0.0016 18.3 0.0 0.018 14.9 0.0 2.6 3 0 0 3 3 3 1 LCCL domain Carn_acyltransf PF00755.15 GAO87139.1 - 6.1e-184 612.4 0.0 7.1e-184 612.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase priB_priC PF07445.7 GAO87140.1 - 0.0011 18.4 1.1 0.0011 18.4 0.8 1.8 2 0 0 2 2 2 1 Primosomal replication protein priB and priC Striatin PF08232.7 GAO87140.1 - 0.0093 16.2 1.4 3.9 7.7 0.1 2.4 2 0 0 2 2 2 2 Striatin family bZIP_1 PF00170.16 GAO87140.1 - 0.023 14.6 0.3 0.023 14.6 0.2 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 GAO87140.1 - 0.036 13.5 8.5 0.19 11.2 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF16 PF01519.11 GAO87140.1 - 0.062 13.5 0.6 0.062 13.5 0.4 1.4 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF2046 PF09755.4 GAO87140.1 - 0.092 11.6 9.5 0.018 13.9 3.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) MerR-DNA-bind PF09278.6 GAO87140.1 - 0.12 12.7 10.6 0.15 12.5 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding SlyX PF04102.7 GAO87140.1 - 0.13 12.7 9.6 1.1 9.7 3.2 2.4 2 0 0 2 2 2 0 SlyX IncA PF04156.9 GAO87140.1 - 0.16 11.5 11.7 0.97 8.9 0.1 2.2 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 GAO87140.1 - 0.21 10.4 5.2 3 6.7 0.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DASH_Spc34 PF08657.5 GAO87140.1 - 0.35 10.5 6.0 2.6 7.6 2.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2968 PF11180.3 GAO87140.1 - 0.41 10.0 15.9 0.2 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Spc24 PF08286.6 GAO87140.1 - 0.59 9.8 6.6 8.9 6.0 2.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Nsp1_C PF05064.8 GAO87140.1 - 0.74 9.4 6.7 1.6 8.3 2.9 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 GAO87140.1 - 1.1 9.1 3.2 13 5.7 0.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 GAO87140.1 - 1.7 8.7 5.7 27 4.8 2.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SPX PF03105.14 GAO87140.1 - 5.3 6.7 6.3 0.17 11.6 0.2 1.6 2 0 0 2 2 2 0 SPX domain DUF2383 PF09537.5 GAO87140.1 - 6 7.1 6.2 14 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Tnp_P_element PF12017.3 GAO87140.1 - 6.3 5.9 5.8 5.5 6.1 0.1 2.1 2 0 0 2 2 2 0 Transposase protein MFS_1 PF07690.11 GAO87141.1 - 2.8e-24 85.4 24.2 2.8e-24 85.4 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.14 GAO87142.1 - 3.1e-23 81.3 0.0 4.4e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sec62 PF03839.11 GAO87144.1 - 5.9e-55 186.1 0.5 5.9e-55 186.1 0.3 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 PAT1 PF09770.4 GAO87144.1 - 7.2 4.7 37.3 9.6 4.3 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lectin_C PF00059.16 GAO87145.1 - 0.064 13.9 0.2 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Lectin C-type domain Syndecan PF01034.15 GAO87145.1 - 0.23 11.1 0.8 0.68 9.6 0.5 1.7 1 0 0 1 1 1 0 Syndecan domain AAA_32 PF13654.1 GAO87146.1 - 0.19 10.3 0.2 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 GAO87147.1 - 2.1e-06 27.7 0.0 4.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO87147.1 - 3.1e-05 24.1 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87147.1 - 0.00034 20.5 0.0 0.00082 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO87147.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO87147.1 - 0.057 11.8 0.0 0.093 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 GAO87147.1 - 0.063 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAO87147.1 - 0.065 12.3 0.0 0.41 9.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Cerato-platanin PF07249.7 GAO87148.1 - 5.4e-51 171.6 0.4 6.3e-51 171.3 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 GAO87148.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Barwin family Git3 PF11710.3 GAO87149.1 - 1e-24 87.2 9.1 1e-24 87.2 6.3 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAO87149.1 - 3.5e-10 39.4 0.1 1.1e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 GAO87149.1 - 0.0011 18.2 8.7 0.0012 18.0 5.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPDPase_memb PF10110.4 GAO87149.1 - 0.0013 18.1 0.6 0.0039 16.6 0.4 1.8 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Nterm_IS4 PF13006.2 GAO87149.1 - 0.12 12.4 0.8 0.41 10.7 0.1 2.2 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal GFA PF04828.9 GAO87150.1 - 2.6e-19 68.9 8.4 7e-10 38.7 0.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.13 GAO87151.1 - 7.7e-05 21.6 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3087 PF11286.3 GAO87151.1 - 0.15 11.2 0.2 0.31 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) polyprenyl_synt PF00348.12 GAO87152.1 - 1.3e-33 116.0 0.0 5.5e-32 110.6 0.0 2.1 1 1 1 2 2 2 2 Polyprenyl synthetase ANTAR PF03861.9 GAO87152.1 - 0.097 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 ANTAR domain HET PF06985.6 GAO87155.1 - 4.3e-21 75.5 6.2 1.5e-18 67.2 0.8 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 GAO87155.1 - 6.1e-11 41.6 25.5 1.2e-05 24.7 7.3 3.3 3 0 0 3 3 3 2 Zinc finger, ZZ type HTH_Tnp_1_2 PF13022.1 GAO87155.1 - 0.16 11.7 0.2 7.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase MFS_1 PF07690.11 GAO87156.1 - 1.5e-42 145.5 74.9 2.2e-34 118.7 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87156.1 - 0.00097 17.8 34.1 0.012 14.1 11.4 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAO87156.1 - 0.0015 18.2 2.4 0.0046 16.7 0.3 2.8 3 0 0 3 3 3 1 MFS_1 like family RelA_SpoT PF04607.12 GAO87157.1 - 1.7e-12 47.3 0.8 3.3e-12 46.4 0.5 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Methyltransf_11 PF08241.7 GAO87158.1 - 1.5e-09 38.2 0.0 4.3e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87158.1 - 1e-05 25.8 0.0 2.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO87158.1 - 3.2e-05 23.1 0.0 6.6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAO87158.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87158.1 - 0.0002 20.9 0.0 0.00068 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87158.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO87158.1 - 0.023 14.0 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain GDPD_2 PF13653.1 GAO87158.1 - 0.042 14.0 0.2 0.096 12.9 0.1 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 GAO87158.1 - 0.064 12.7 0.1 0.31 10.5 0.0 2.0 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Methyltransf_18 PF12847.2 GAO87158.1 - 0.08 13.5 0.0 0.24 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_62 PF03664.8 GAO87160.1 - 1.2e-81 273.8 9.9 1.4e-81 273.6 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 VWA_3 PF13768.1 GAO87162.1 - 6.2e-28 97.4 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAO87162.1 - 1.3e-19 69.9 0.0 3.4e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 GAO87162.1 - 7.9e-11 42.3 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAO87162.1 - 2.4e-10 39.7 0.0 5.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAO87162.1 - 9.1e-08 32.0 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAO87162.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 GAO87162.1 - 0.0046 16.1 0.0 0.0092 15.1 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein MFS_1 PF07690.11 GAO87163.1 - 1.1e-30 106.5 46.7 1.1e-30 106.5 32.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO87163.1 - 0.26 11.1 4.9 0.35 10.6 0.1 3.0 3 0 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 GAO87163.1 - 1.6 7.2 31.6 0.03 12.8 3.1 2.9 2 2 0 2 2 2 0 Sugar (and other) transporter Mito_fiss_reg PF05308.6 GAO87164.1 - 0.086 12.1 4.4 0.13 11.5 3.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2360 PF10152.4 GAO87164.1 - 0.12 12.6 1.2 0.17 12.1 0.5 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SNF2_N PF00176.18 GAO87165.1 - 4e-05 22.5 0.0 0.00011 21.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain PROCT PF08084.6 GAO87165.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 PROCT (NUC072) domain Glyco_hydro_72 PF03198.9 GAO87166.1 - 9.6e-121 402.5 3.8 1.5e-120 401.9 2.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase DUF726 PF05277.7 GAO87166.1 - 9.7e-114 379.8 0.6 1.7e-113 379.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) X8 PF07983.8 GAO87166.1 - 3.2e-26 91.6 7.5 7.5e-26 90.4 5.2 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 GAO87166.1 - 4.8e-05 22.7 0.2 8.8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_5 PF12695.2 GAO87166.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAO87166.1 - 0.011 15.9 0.1 0.029 14.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 GAO87166.1 - 0.041 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glu-tRNAGln PF02686.10 GAO87167.1 - 6.1e-06 25.9 0.5 2.9e-05 23.7 0.3 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.1 GAO87168.1 - 1.1e-115 385.6 16.2 1.3e-115 385.4 11.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAO87168.1 - 6.6e-06 25.9 19.3 0.0011 18.8 4.9 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO87168.1 - 2.8e-05 23.5 11.6 0.42 10.5 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAO87168.1 - 0.00046 20.4 11.7 1.7 9.2 0.1 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO87168.1 - 0.0006 20.2 16.4 0.12 13.1 0.6 5.8 2 1 5 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO87168.1 - 0.0014 19.2 24.0 0.03 15.0 3.3 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAO87168.1 - 0.0041 16.7 21.2 0.036 13.7 4.1 4.2 1 1 3 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAO87168.1 - 0.0071 16.1 22.9 0.25 11.3 0.1 7.2 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO87168.1 - 0.046 13.3 23.3 0.38 10.4 0.4 6.6 5 1 2 7 7 7 0 Tetratricopeptide repeat DUF2811 PF10929.3 GAO87168.1 - 0.047 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) TPR_8 PF13181.1 GAO87168.1 - 0.075 12.8 0.8 0.075 12.8 0.5 5.4 3 2 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 GAO87168.1 - 0.38 11.4 19.8 0.99 10.2 0.6 6.9 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat DUF663 PF04950.7 GAO87169.1 - 3.6e-96 321.6 0.0 5.7e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAO87169.1 - 3.5e-26 90.5 0.0 8.5e-26 89.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 GAO87170.1 - 4.3e-38 128.6 0.0 1.8e-36 123.4 0.0 2.6 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 GAO87170.1 - 1.4e-06 27.9 0.0 0.0036 17.1 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAO87170.1 - 0.0013 17.6 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region DUF4427 PF14468.1 GAO87170.1 - 0.014 15.0 0.4 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) DUF4319 PF14203.1 GAO87170.1 - 0.048 13.2 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) cobW PF02492.14 GAO87171.1 - 2.4e-34 118.3 0.0 2.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 GAO87171.1 - 4.2e-06 25.7 0.1 0.0062 15.3 0.0 2.0 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 GAO87171.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 GAO87171.1 - 0.019 15.7 0.0 0.039 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAO87171.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAO87171.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAO87171.1 - 0.024 14.0 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.7 GAO87171.1 - 0.044 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.18 GAO87171.1 - 0.045 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 GAO87171.1 - 0.047 13.1 0.0 2.1 7.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 GAO87171.1 - 0.083 12.5 0.0 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_26 PF13500.1 GAO87171.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 GAO87171.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein LIM_bind PF01803.11 GAO87172.1 - 7.5e-78 260.9 1.2 7.5e-78 260.9 0.8 4.3 2 1 1 4 4 4 1 LIM-domain binding protein AAA PF00004.24 GAO87173.1 - 4.8e-40 136.8 0.0 1.8e-37 128.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO87173.1 - 2e-05 24.6 0.5 0.0028 17.6 0.1 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO87173.1 - 4.6e-05 23.5 0.2 0.0029 17.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 GAO87173.1 - 8e-05 21.7 0.1 0.00026 20.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 GAO87173.1 - 0.0003 19.6 0.0 0.00061 18.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 GAO87173.1 - 0.00038 21.2 0.1 0.0032 18.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO87173.1 - 0.00085 19.2 0.5 0.0047 16.8 0.0 2.7 3 2 1 4 4 2 1 AAA domain AAA_19 PF13245.1 GAO87173.1 - 0.00099 18.8 0.4 0.0038 16.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAO87173.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAO87173.1 - 0.0048 16.3 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 GAO87173.1 - 0.0051 16.7 0.1 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAO87173.1 - 0.0059 16.5 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAO87173.1 - 0.015 14.5 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAO87173.1 - 0.021 14.9 0.0 0.075 13.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase SHQ1 PF04925.10 GAO87173.1 - 0.036 13.5 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein AAA_24 PF13479.1 GAO87173.1 - 0.04 13.5 0.2 0.15 11.6 0.2 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO87173.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAO87173.1 - 0.076 12.9 0.0 1.2 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IPT PF01745.11 GAO87173.1 - 0.16 11.1 0.0 0.44 9.6 0.0 1.7 1 0 0 1 1 1 0 Isopentenyl transferase DUF4050 PF13259.1 GAO87174.1 - 2.6e-42 143.6 0.0 3.8e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DSBA PF01323.15 GAO87175.1 - 4.3e-26 91.6 0.2 1.3e-24 86.8 0.2 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 GAO87175.1 - 0.0014 18.3 0.1 0.11 12.2 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 GAO87175.1 - 0.017 15.0 0.0 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Mus7 PF09462.5 GAO87176.1 - 9.7e-231 767.8 0.0 1.5e-230 767.2 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.7 GAO87178.1 - 8.4e-29 100.1 11.5 8.4e-29 100.1 8.0 2.5 3 0 0 3 3 3 1 PAPA-1-like conserved region BSP_II PF05432.6 GAO87178.1 - 0.0026 17.1 19.0 0.0026 17.1 13.1 2.5 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Pex14_N PF04695.8 GAO87179.1 - 2.8e-35 121.3 1.4 2.8e-35 121.3 0.9 2.8 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 GAO87180.1 - 2.3e-18 65.3 11.1 9.2e-06 25.3 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 GAO87180.1 - 5.4e-14 52.2 0.1 5.4e-14 52.2 0.1 3.4 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 GAO87180.1 - 0.0022 17.4 0.1 3.5 7.2 0.0 4.6 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.2 GAO87180.1 - 0.045 13.4 0.3 0.2 11.3 0.2 2.0 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 RRM_1 PF00076.17 GAO87181.1 - 2.7e-17 62.1 0.0 4.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO87181.1 - 1.2e-12 47.6 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO87181.1 - 6e-10 38.8 0.0 9.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAO87181.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.6 GAO87182.1 - 1.6e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 GAO87183.1 - 1.1e-18 66.9 8.6 1.4e-18 66.6 5.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 GAO87183.1 - 0.012 14.9 1.5 0.026 13.9 1.0 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UCR_hinge PF02320.11 GAO87183.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 GAO87183.1 - 0.077 12.9 0.8 0.19 11.7 0.5 1.7 1 1 0 1 1 1 0 CHCH domain Mito_carr PF00153.22 GAO87184.1 - 1.6e-50 168.7 0.6 6.7e-20 70.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_3 PF13640.1 GAO87185.1 - 4.5e-07 30.3 0.1 1e-06 29.1 0.1 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAO87185.1 - 0.0094 15.5 0.1 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 GAO87185.1 - 0.1 12.6 0.0 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) tRNA-synt_2d PF01409.15 GAO87186.1 - 3.5e-47 160.6 0.0 6e-25 87.8 0.0 2.7 2 2 1 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 GAO87186.1 - 1.4e-28 98.9 0.0 4.5e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain AraC_binding_2 PF14525.1 GAO87186.1 - 0.037 13.6 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 AraC-binding-like domain GrpE PF01025.14 GAO87187.1 - 7.8e-44 149.1 6.3 1.1e-43 148.5 4.3 1.3 1 0 0 1 1 1 1 GrpE DinB PF05163.7 GAO87187.1 - 0.1 12.3 1.2 0.24 11.0 0.0 2.0 1 1 1 2 2 2 0 DinB family M60-like PF13402.1 GAO87187.1 - 0.13 11.1 1.1 0.37 9.6 0.4 1.8 1 1 1 2 2 2 0 Peptidase M60-like family DUF4613 PF15390.1 GAO87187.1 - 0.28 9.3 4.6 0.37 8.9 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) TMF_DNA_bd PF12329.3 GAO87187.1 - 4.1 7.2 13.7 2.1 8.2 5.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Bap31 PF05529.7 GAO87187.1 - 5.2 6.4 9.4 3.2 7.1 5.1 1.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Abhydrolase_3 PF07859.8 GAO87188.1 - 1.8e-55 187.8 0.0 2.3e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO87188.1 - 8e-06 25.6 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO87188.1 - 3.8e-05 23.6 0.9 8.1e-05 22.6 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO87188.1 - 8.4e-05 21.8 0.0 0.00098 18.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 GAO87188.1 - 9.6e-05 21.2 0.0 0.00023 20.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydro_lipase PF04083.11 GAO87188.1 - 0.0019 17.5 0.1 0.0049 16.1 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 GAO87188.1 - 0.0028 16.9 0.2 0.0068 15.7 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2424 PF10340.4 GAO87188.1 - 0.0059 15.2 0.0 0.0084 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Calcipressin PF04847.7 GAO87189.1 - 7.7e-32 110.3 0.7 1.1e-31 109.8 0.5 1.2 1 0 0 1 1 1 1 Calcipressin ATE_C PF04377.10 GAO87190.1 - 1e-46 158.1 2.8 1.6e-46 157.5 2.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 GAO87190.1 - 6.8e-22 77.0 3.4 1.6e-21 75.8 2.4 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 GAO87190.1 - 0.017 15.0 0.4 0.032 14.2 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 GAO87191.1 - 5.1e-16 58.5 0.1 6.1e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.21 GAO87192.1 - 2.1e-32 111.6 0.0 3.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAO87192.1 - 3.9e-13 48.3 0.0 5.1e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cytochrom_C PF00034.16 GAO87193.1 - 2.5e-08 34.6 0.1 8.6e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAO87193.1 - 6.5e-06 26.2 2.7 3.1e-05 24.0 1.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAO87193.1 - 0.003 17.0 0.1 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c-550 domain Baculo_PEP_C PF04513.7 GAO87193.1 - 0.42 10.4 4.1 0.42 10.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_A PF00119.15 GAO87194.1 - 0.17 11.3 1.1 0.24 10.8 0.7 1.1 1 0 0 1 1 1 0 ATP synthase A chain RNase_PH PF01138.16 GAO87195.1 - 6.6e-10 39.4 0.0 1e-08 35.5 0.0 2.7 3 1 0 3 3 3 1 3' exoribonuclease family, domain 1 Pkinase PF00069.20 GAO87196.1 - 5.2e-60 202.7 0.0 7.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87196.1 - 7.8e-33 113.6 0.0 2.1e-30 105.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAO87196.1 - 0.055 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 GAO87197.1 - 3.3e-25 87.9 14.4 3.4e-25 87.9 9.2 1.6 2 0 0 2 2 2 1 Stc1 domain Herpes_US12 PF05363.7 GAO87197.1 - 0.055 13.9 0.4 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus US12 family Stn1 PF10451.4 GAO87199.1 - 8.6e-12 44.4 0.4 1.2e-10 40.7 0.3 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 GAO87199.1 - 0.00089 19.0 0.3 0.015 15.1 0.1 2.7 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain BAAT_C PF08840.6 GAO87200.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 GAO87200.1 - 0.0036 16.6 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAO87200.1 - 0.023 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO87200.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 GAO87200.1 - 0.088 11.2 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1335 PF07056.6 GAO87201.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) Glyco_hydro_43 PF04616.9 GAO87202.1 - 1e-65 221.6 4.1 1.4e-65 221.2 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 dCMP_cyt_deam_1 PF00383.17 GAO87203.1 - 4.1e-11 42.4 0.0 1.5e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 GAO87203.1 - 0.0033 17.0 0.1 0.0098 15.5 0.1 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain DUF2630 PF10944.3 GAO87203.1 - 0.046 13.8 0.5 0.073 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DnaJ PF00226.26 GAO87204.1 - 1.3e-24 85.7 3.1 1.3e-24 85.7 2.2 2.6 3 0 0 3 3 3 1 DnaJ domain DUF1488 PF07369.6 GAO87204.1 - 0.022 14.5 0.1 0.11 12.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) DUF4658 PF15555.1 GAO87204.1 - 0.032 14.1 0.6 0.032 14.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) YqaJ PF09588.5 GAO87204.1 - 0.034 14.1 4.8 3.2 7.7 1.2 2.5 2 1 0 2 2 2 0 YqaJ-like viral recombinase domain Acetyltransf_11 PF13720.1 GAO87204.1 - 0.69 10.1 4.1 5.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 V_ATPase_I PF01496.14 GAO87204.1 - 4.9 4.8 6.0 7.1 4.3 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Usp PF00582.21 GAO87205.1 - 1.4e-17 64.1 0.2 7e-13 48.9 0.1 2.8 2 0 0 2 2 2 2 Universal stress protein family IPI_T4 PF11634.3 GAO87205.1 - 0.033 14.0 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 ATP-synt_ab PF00006.20 GAO87206.1 - 4.5e-61 206.0 0.0 5.8e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAO87206.1 - 2.6e-16 60.1 0.0 4.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAO87206.1 - 0.0014 18.8 0.1 0.24 11.6 0.1 2.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAO87206.1 - 0.038 13.9 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain Trp_syntA PF00290.15 GAO87207.1 - 1.3e-93 312.3 0.0 2.4e-93 311.3 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 GAO87207.1 - 1.4e-43 149.3 0.8 2.2e-43 148.6 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 GAO87209.1 - 7.7e-24 83.7 0.4 1.4e-23 82.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO87209.1 - 3.2e-09 37.7 0.1 8.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO87209.1 - 4.7e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 GAO87209.1 - 0.024 14.9 0.8 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 GAO87209.1 - 0.032 14.2 0.5 0.064 13.2 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding Aminotran_5 PF00266.14 GAO87211.1 - 3.3e-21 75.4 0.0 6.5e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GYF PF02213.11 GAO87211.1 - 1.6e-17 62.8 0.1 3.4e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain Amidohydro_3 PF07969.6 GAO87212.1 - 6.4e-59 200.1 12.6 8.9e-59 199.7 8.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Fis1_TPR_C PF14853.1 GAO87212.1 - 8.7e-25 86.3 0.6 1.6e-24 85.5 0.4 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 GAO87212.1 - 2.5e-16 58.6 0.0 5.4e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.1 GAO87212.1 - 3.9e-16 58.6 14.3 3.2e-14 52.4 5.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 GAO87212.1 - 2.2e-12 46.4 7.3 1.2e-09 37.6 2.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Amidohydro_5 PF13594.1 GAO87212.1 - 3.2e-10 39.6 0.1 9.1e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase zf-C3HC4_2 PF13923.1 GAO87212.1 - 4.9e-09 36.0 12.5 2.7e-08 33.7 5.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO87212.1 - 1.1e-07 31.8 3.7 1.1e-07 31.8 2.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger Amidohydro_1 PF01979.15 GAO87212.1 - 9.3e-07 28.8 0.9 0.0016 18.1 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family zf-C3HC4 PF00097.20 GAO87212.1 - 1.1e-06 28.1 14.7 3.6e-06 26.5 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 GAO87212.1 - 3.3e-05 23.7 5.3 0.00038 20.3 0.4 2.7 2 0 0 2 2 2 1 zinc-finger zf-RING_5 PF14634.1 GAO87212.1 - 4.7e-05 23.0 12.7 0.00013 21.5 3.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain TPR_2 PF07719.12 GAO87212.1 - 0.023 14.5 1.7 0.072 13.0 1.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 GAO87212.1 - 0.07 12.9 8.5 0.025 14.3 2.0 2.5 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAO87212.1 - 0.32 10.6 10.7 0.45 10.1 2.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.14 GAO87212.1 - 0.37 10.5 4.7 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-TFIIB PF13453.1 GAO87212.1 - 0.38 9.9 6.7 0.78 8.9 0.1 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger Baculo_RING PF05883.6 GAO87212.1 - 0.8 9.5 1.4 3.1 7.6 0.5 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 GAO87212.1 - 1.7 8.4 5.4 4.4 7.1 3.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 GAO87212.1 - 6.4 6.5 13.5 0.43 10.3 4.2 2.4 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 GAO87212.1 - 7.6 6.4 7.5 7 6.5 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon Spc24 PF08286.6 GAO87213.1 - 7.7e-40 135.2 1.3 1.8e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 EPO_TPO PF00758.13 GAO87213.1 - 0.052 13.1 0.3 0.07 12.7 0.2 1.2 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin IL2 PF00715.12 GAO87213.1 - 0.054 13.2 0.4 0.12 12.0 0.2 1.6 1 1 1 2 2 2 0 Interleukin 2 WXG100 PF06013.7 GAO87213.1 - 0.067 13.2 3.0 0.25 11.3 0.1 2.7 1 1 1 3 3 3 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.14 GAO87213.1 - 0.086 10.6 2.1 0.092 10.5 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4613 PF15390.1 GAO87213.1 - 0.2 9.7 2.6 0.24 9.5 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) APG6 PF04111.7 GAO87213.1 - 0.2 10.6 8.1 0.26 10.2 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 GAO87213.1 - 0.34 9.2 2.2 0.35 9.2 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family YjcZ PF13990.1 GAO87213.1 - 0.35 9.9 4.3 0.51 9.4 3.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein DMPK_coil PF08826.5 GAO87213.1 - 1.3 8.9 11.0 2.8 7.8 1.0 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like TBPIP PF07106.8 GAO87213.1 - 1.8 8.1 5.6 13 5.2 3.9 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 GAO87213.1 - 2 8.2 8.4 2.7 7.8 1.8 2.3 1 1 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 GAO87213.1 - 2.5 7.5 9.1 0.55 9.6 1.6 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SlyX PF04102.7 GAO87213.1 - 3.5 8.0 5.7 5.5 7.4 0.2 2.5 2 1 0 2 2 2 0 SlyX DUF972 PF06156.8 GAO87213.1 - 5 7.5 7.3 2.6 8.4 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF607 PF04678.8 GAO87213.1 - 5.2 6.9 8.1 13 5.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Syntaxin PF00804.20 GAO87213.1 - 5.7 7.1 9.0 6.1 7.0 3.3 2.2 1 1 1 2 2 2 0 Syntaxin DUF2034 PF10356.4 GAO87214.1 - 3.5e-44 150.1 0.0 5.6e-27 94.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 GAO87214.1 - 6.3e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 GAO87215.1 - 5.2e-55 185.3 1.3 9.2e-49 165.1 0.0 2.2 2 0 0 2 2 2 2 Subunit 21 of Mediator complex TMCO5 PF14992.1 GAO87215.1 - 0.0039 16.3 0.2 0.0055 15.8 0.1 1.2 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 GAO87215.1 - 0.0058 16.3 0.8 0.0058 16.3 0.6 2.9 2 2 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 GAO87215.1 - 0.076 12.0 1.9 0.11 11.5 1.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4071 PF13281.1 GAO87215.1 - 0.11 11.2 0.4 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) CENP-Q PF13094.1 GAO87215.1 - 1.4 8.9 5.9 3 7.8 4.1 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SNF2_N PF00176.18 GAO87216.1 - 4.6e-63 212.7 0.1 6.7e-63 212.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO87216.1 - 1.4e-09 37.6 0.1 1.2e-06 28.3 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 GAO87216.1 - 6.7e-07 28.9 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.6 GAO87216.1 - 0.0013 18.6 0.0 0.0049 16.7 0.0 2.0 1 0 0 1 1 1 1 HIRAN domain zf-RING_5 PF14634.1 GAO87216.1 - 0.0092 15.6 1.4 0.016 14.8 1.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAO87216.1 - 0.033 14.0 2.1 0.066 13.0 1.4 1.5 1 0 0 1 1 1 0 Ring finger domain PI3_PI4_kinase PF00454.22 GAO87217.1 - 3.4e-32 111.7 0.0 4.6e-31 108.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3386 PF11866.3 GAO87217.1 - 0.023 13.8 0.1 0.053 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) GATA PF00320.22 GAO87218.1 - 8.2e-16 57.0 2.6 1.4e-15 56.2 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.7 GAO87218.1 - 0.0065 16.1 0.9 0.0065 16.1 0.6 3.3 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.7 GAO87218.1 - 0.018 14.3 0.4 0.033 13.4 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GAS PF13851.1 GAO87218.1 - 0.032 13.4 0.7 0.049 12.8 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 GAO87218.1 - 0.046 13.7 3.3 0.16 11.9 2.3 1.8 1 1 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 GAO87218.1 - 0.05 13.4 5.8 2.6 7.8 2.4 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ArfGap PF01412.13 GAO87218.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf IncA PF04156.9 GAO87218.1 - 0.12 11.9 2.4 0.24 10.9 1.7 1.4 1 0 0 1 1 1 0 IncA protein WD40_alt PF14077.1 GAO87218.1 - 2.1 8.0 4.4 32 4.2 0.0 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif zf-C4H2 PF10146.4 GAO87218.1 - 2.9 7.8 9.1 0.6 10.0 1.6 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein MFS_1 PF07690.11 GAO87219.1 - 6.9e-15 54.6 23.0 6.9e-15 54.6 15.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 GAO87219.1 - 6.5e-14 51.7 0.1 1.6e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Nodulin-like Serinc PF03348.10 GAO87220.1 - 1.1e-175 584.4 13.6 1.3e-175 584.2 9.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MutL_C PF08676.6 GAO87221.1 - 2e-23 82.5 0.0 4.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 GAO87221.1 - 3.2e-19 68.5 0.0 3.3e-18 65.2 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAO87221.1 - 2e-14 53.4 0.0 5.6e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAO87221.1 - 1.9e-13 50.1 0.1 1.3e-12 47.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.8 GAO87222.1 - 3.6e-13 49.3 3.9 6.8e-13 48.5 2.7 1.5 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) PilJ PF13675.1 GAO87222.1 - 0.027 14.7 4.1 0.038 14.2 2.9 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3552 PF12072.3 GAO87222.1 - 0.044 12.9 4.5 0.035 13.3 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Transposase_22 PF02994.9 GAO87222.1 - 0.069 11.6 0.3 0.077 11.4 0.2 1.1 1 0 0 1 1 1 0 L1 transposable element Fez1 PF06818.10 GAO87222.1 - 0.092 12.7 5.1 0.11 12.4 3.6 1.1 1 0 0 1 1 1 0 Fez1 HAUS6_N PF14661.1 GAO87222.1 - 0.092 12.0 1.1 0.11 11.8 0.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NYD-SP28_assoc PF14775.1 GAO87222.1 - 0.25 11.0 2.6 0.28 10.9 0.7 1.9 1 1 1 2 2 2 0 Sperm tail C-terminal domain APG6 PF04111.7 GAO87222.1 - 0.58 9.1 4.4 0.83 8.6 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Chitin_synth_2 PF03142.10 GAO87223.1 - 1.6e-229 762.7 0.0 2.2e-229 762.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAO87223.1 - 4.1e-89 299.4 0.0 7.7e-89 298.5 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 GAO87223.1 - 6.7e-19 67.4 0.0 2.2e-10 40.1 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 GAO87223.1 - 2.9e-17 62.1 0.9 2.4e-16 59.2 0.4 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 GAO87223.1 - 5.1e-17 62.2 2.1 5.1e-17 62.2 1.4 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO87223.1 - 2.3e-14 53.7 0.0 4.2e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAO87223.1 - 6.7e-06 25.4 0.0 1.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAO87223.1 - 0.0063 16.2 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 GAO87224.1 - 2.7e-261 867.5 1.2 3.9e-261 867.0 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAO87224.1 - 5.2e-185 616.4 0.0 7e-185 615.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 GAO87224.1 - 7.1e-22 77.0 0.0 1.9e-17 62.7 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 GAO87224.1 - 1.2e-17 63.3 0.8 1.7e-16 59.7 0.4 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 GAO87224.1 - 1e-16 61.4 0.2 2.4e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAO87224.1 - 8.1e-15 55.0 4.1 1.9e-14 53.8 2.9 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAO87224.1 - 0.00014 21.5 0.0 0.0083 15.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAO87224.1 - 0.00022 20.5 0.1 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.1 GAO87224.1 - 0.013 15.6 0.2 0.096 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAO87224.1 - 0.013 15.4 0.6 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 GAO87224.1 - 0.12 11.5 0.0 0.3 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAO87224.1 - 0.19 12.0 0.4 0.42 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Dynactin PF12455.3 GAO87225.1 - 1.8e-96 322.2 8.5 1.8e-96 322.2 5.9 3.9 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 GAO87225.1 - 1.3e-23 82.4 0.1 2.2e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.13 GAO87225.1 - 0.021 14.5 0.7 0.021 14.5 0.5 9.2 8 1 1 9 9 9 0 Homeobox associated leucine zipper DUF869 PF05911.6 GAO87225.1 - 0.1 10.7 74.3 0.0029 15.9 3.6 4.3 2 1 2 4 4 4 0 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 GAO87225.1 - 3.1 7.6 92.9 0.21 11.4 12.1 9.1 7 2 2 9 9 9 0 TATA element modulatory factor 1 DNA binding Alpha-amylase PF00128.19 GAO87226.1 - 8.8e-68 229.0 0.3 1.6e-67 228.1 0.2 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO87226.1 - 1.3e-29 102.0 0.0 3.2e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) HAD_2 PF13419.1 GAO87229.1 - 1.7e-28 99.9 0.1 2.1e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO87229.1 - 8.3e-05 22.2 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO87229.1 - 0.0024 18.3 0.0 0.0027 18.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 5_nucleotid PF05761.9 GAO87229.1 - 0.017 13.6 0.1 0.022 13.2 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family KH_1 PF00013.24 GAO87231.1 - 6.6e-29 99.3 2.5 1e-07 31.4 0.2 7.3 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 GAO87231.1 - 7.9e-24 82.8 2.0 0.00029 20.4 0.0 6.9 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 GAO87231.1 - 0.093 12.4 0.6 0.2 11.3 0.4 1.6 1 0 0 1 1 1 0 GHKL domain SUV3_C PF12513.3 GAO87231.1 - 0.17 11.3 0.0 0.63 9.5 0.0 2.1 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Solute_trans_a PF03619.11 GAO87232.1 - 1.1e-100 336.4 4.1 1.4e-100 336.1 2.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 GAO87234.1 - 4.7e-60 202.2 0.1 6.4e-60 201.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAO87234.1 - 1.3e-36 124.8 0.0 4.1e-36 123.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 GAO87234.1 - 1.4e-21 76.1 0.0 4e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAO87234.1 - 2.5e-12 46.7 0.8 5.8e-11 42.3 0.0 3.3 4 0 0 4 4 4 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAO87234.1 - 7.9e-12 44.8 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAO87234.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 GAO87235.1 - 4.3e-10 39.4 0.4 5.9e-09 35.7 0.0 2.7 3 0 0 3 3 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO87235.1 - 2.6e-09 36.8 0.0 5.4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 GAO87235.1 - 3.7e-09 36.5 0.0 1.3e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 GAO87235.1 - 2.1e-08 33.6 0.2 1.1e-05 24.9 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO87235.1 - 4.9e-07 29.4 0.0 1.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 GAO87235.1 - 0.0023 17.5 1.0 0.0042 16.7 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 GAO87235.1 - 0.0044 16.8 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1330) AAA_23 PF13476.1 GAO87235.1 - 0.14 12.4 6.0 0.26 11.5 4.2 1.4 1 0 0 1 1 1 0 AAA domain RRM_3 PF08777.6 GAO87235.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif Rifin_STEVOR PF02009.11 GAO87235.1 - 0.61 9.6 6.3 0.95 9.0 4.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family Atg14 PF10186.4 GAO87235.1 - 2.2 7.1 11.2 3.3 6.5 7.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF106 PF01956.11 GAO87235.1 - 6.8 6.1 5.6 12 5.3 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Borrelia_P83 PF05262.6 GAO87235.1 - 7.6 4.6 12.6 11 4.1 8.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 GAO87235.1 - 8.5 5.2 14.3 13 4.5 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyoxalase PF00903.20 GAO87236.1 - 1.9e-10 40.7 0.0 5.4e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO87236.1 - 1.2e-09 38.7 0.0 2.3e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAO87236.1 - 0.00094 19.1 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Nucleo_P87 PF07267.6 GAO87237.1 - 0.24 10.0 3.7 0.33 9.5 2.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF663 PF04950.7 GAO87238.1 - 1e-92 310.3 0.0 1e-92 310.3 0.0 2.4 3 0 0 3 3 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAO87238.1 - 1.2e-25 88.8 0.0 2.5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 GAO87238.1 - 1.7e-06 27.6 0.0 0.00026 20.4 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAO87238.1 - 1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO87238.1 - 2.4e-05 24.4 0.2 8.8e-05 22.5 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 GAO87238.1 - 0.00021 21.2 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 GAO87238.1 - 0.00023 20.8 0.2 0.00055 19.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAO87238.1 - 0.00036 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO87238.1 - 0.00068 20.4 0.0 0.00068 20.4 0.0 4.9 3 1 0 4 4 2 1 AAA domain AAA PF00004.24 GAO87238.1 - 0.00092 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 GAO87238.1 - 0.00097 19.6 0.0 0.0031 17.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 GAO87238.1 - 0.0012 19.1 1.7 0.0046 17.2 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_19 PF13245.1 GAO87238.1 - 0.002 17.8 0.4 0.0058 16.3 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 GAO87238.1 - 0.0029 17.2 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.4 GAO87238.1 - 0.0051 16.3 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 GAO87238.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO87238.1 - 0.01 15.2 0.0 0.031 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAO87238.1 - 0.012 15.3 0.3 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 GAO87238.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 GAO87238.1 - 0.013 15.0 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 GAO87238.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAO87238.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 GAO87238.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 GAO87238.1 - 0.036 13.7 0.2 0.14 11.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 GAO87238.1 - 0.067 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.17 GAO87238.1 - 0.087 12.2 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 GAO87238.1 - 0.18 11.2 0.1 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1989 PF09347.5 GAO87239.1 - 3.6e-54 182.6 0.0 5.4e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Inhibitor_I9 PF05922.11 GAO87239.1 - 3.2e-05 24.4 0.1 6.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 BCDHK_Adom3 PF10436.4 GAO87240.1 - 3e-43 147.1 0.0 4.3e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAO87240.1 - 1.8e-16 59.7 0.0 9.6e-16 57.4 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAO87240.1 - 0.043 13.4 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MmgE_PrpD PF03972.9 GAO87241.1 - 7.3e-106 354.0 0.0 1e-105 353.5 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PLDc_2 PF13091.1 GAO87241.1 - 1.2e-20 73.5 0.0 5.8e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAO87241.1 - 0.0021 17.8 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 GAO87241.1 - 0.015 14.2 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB TPP_enzyme_N PF02776.13 GAO87242.1 - 3.1e-41 140.7 0.0 1.2e-40 138.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO87242.1 - 5.5e-22 78.0 0.0 1.8e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAO87242.1 - 1.4e-19 70.1 0.0 3e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aminotran_1_2 PF00155.16 GAO87243.1 - 3.5e-20 72.2 0.0 4.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.20 GAO87244.1 - 4.1e-56 190.0 0.0 5.5e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87244.1 - 4.1e-42 144.0 0.0 6.5e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87244.1 - 2.3e-06 26.7 0.0 3.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO87244.1 - 0.0012 18.5 0.1 0.004 16.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO87244.1 - 0.004 16.2 0.2 0.013 14.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAO87244.1 - 0.085 12.1 0.3 0.46 9.8 0.2 2.0 1 1 0 1 1 1 0 RIO1 family Exo_endo_phos PF03372.18 GAO87245.1 - 5.8e-13 49.3 0.0 7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3982 PF13138.1 GAO87246.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Pkinase PF00069.20 GAO87247.1 - 1.3e-70 237.5 0.0 1.7e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87247.1 - 1.2e-33 116.3 0.0 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87247.1 - 0.00011 21.3 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAO87247.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 GAO87247.1 - 0.095 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 GAO87248.1 - 3.7e-27 94.4 0.1 5e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO87248.1 - 2.1e-07 30.7 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO87248.1 - 3.6e-05 23.6 0.1 4.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 RWD domain Complex1_49kDa PF00346.14 GAO87249.1 - 9.3e-134 444.6 0.0 1.2e-133 444.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 GAO87249.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.21 GAO87250.1 - 3.5e-26 91.5 0.0 5.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAO87250.1 - 3.7e-13 48.3 0.0 5e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 GAO87251.1 - 5.2e-39 133.1 0.2 3.4e-38 130.5 0.0 2.0 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 GAO87251.1 - 1.6e-30 104.7 0.2 2.9e-30 103.8 0.2 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 GAO87251.1 - 1.5e-23 82.1 1.3 2.7e-23 81.2 0.9 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAO87251.1 - 2.8e-13 49.0 3.3 2.8e-13 49.0 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 GAO87251.1 - 6.9e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 GAO87251.1 - 0.00012 22.1 0.3 0.0003 20.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBA_e1_C PF09358.5 GAO87251.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain TrkA_N PF02254.13 GAO87251.1 - 0.073 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Cu-oxidase_2 PF07731.9 GAO87251.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Pyr_redox PF00070.22 GAO87251.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Telomere_reg-2 PF10193.4 GAO87252.1 - 4.5e-35 120.3 0.0 1.8e-34 118.4 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein Ebola_NP PF05505.7 GAO87252.1 - 0.12 10.4 4.9 0.19 9.7 3.4 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein DUF1475 PF07343.6 GAO87252.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) Sec1 PF00995.18 GAO87253.1 - 5.6e-131 437.9 0.0 6.3e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SNARE PF05739.14 GAO87254.1 - 0.0063 16.1 0.9 0.0063 16.1 0.6 2.9 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 GAO87254.1 - 0.022 14.8 1.2 2.3 8.3 0.1 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus PGC7_Stella PF15549.1 GAO87254.1 - 5.4 6.9 11.0 1.4 8.9 5.3 1.7 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain zf-H2C2_2 PF13465.1 GAO87255.1 - 7.5e-12 44.9 15.4 4.9e-06 26.5 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAO87255.1 - 1.9e-09 37.2 14.2 1.5e-05 25.0 3.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO87255.1 - 1.8e-07 31.0 8.3 0.00016 21.7 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAO87255.1 - 4.6e-06 26.6 1.5 1.5e-05 24.9 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO87255.1 - 3.9e-05 23.6 5.7 9.3e-05 22.4 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAO87255.1 - 0.00012 21.8 6.9 0.0031 17.3 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAO87255.1 - 0.047 13.8 1.2 0.047 13.8 0.8 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 GAO87255.1 - 0.39 10.4 3.8 4.7 6.9 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 GAO87255.1 - 1.6 8.5 6.7 0.53 10.0 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 GAO87255.1 - 3 8.2 8.9 5.2 7.4 1.2 3.3 2 1 1 3 3 3 0 C2H2-type zinc-finger domain SF3b1 PF08920.5 GAO87256.1 - 5.9e-46 156.1 0.2 5.9e-46 156.1 0.2 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 GAO87256.1 - 5.1e-16 58.7 3.3 0.011 15.9 0.0 7.8 6 3 4 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 GAO87256.1 - 1.4e-10 41.3 5.1 0.54 10.8 0.0 8.2 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 GAO87256.1 - 6.1e-10 38.3 12.3 0.15 12.1 0.3 8.9 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 GAO87256.1 - 5.5e-06 26.6 1.3 0.96 9.8 0.0 5.7 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 GAO87256.1 - 9.4e-06 24.2 0.6 0.014 13.7 0.1 3.2 2 1 1 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 GAO87256.1 - 0.0036 16.6 0.3 3.9 6.7 0.0 4.0 5 0 0 5 5 5 1 NUC173 domain CLASP_N PF12348.3 GAO87256.1 - 0.0042 16.4 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.2 GAO87256.1 - 0.0048 16.7 0.9 25 4.6 0.0 4.7 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B56 PF01603.15 GAO87256.1 - 0.26 9.8 0.0 1.7 7.1 0.0 2.3 2 1 1 3 3 3 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3455 PF11937.3 GAO87257.1 - 2.3e-22 79.7 0.0 2.5e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Ldh_2 PF02615.9 GAO87258.1 - 1.2e-102 343.0 0.0 1.4e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase SAP PF02037.22 GAO87259.1 - 3.2e-11 42.4 0.5 8.9e-11 41.0 0.0 2.0 2 0 0 2 2 2 1 SAP domain TraF PF13728.1 GAO87259.1 - 6.1 6.2 7.8 1.5 8.2 0.8 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Methyltransf_11 PF08241.7 GAO87260.1 - 0.011 16.1 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CBM_21 PF03370.8 GAO87261.1 - 3.9e-37 126.6 2.2 8e-37 125.6 1.5 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 GAO87262.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAO87262.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 GAO87262.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 GAO87262.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAO87262.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 GAO87262.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 GAO87262.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Mito_carr PF00153.22 GAO87263.1 - 3.7e-43 145.1 0.3 1.5e-16 59.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 GAO87263.1 - 0.026 14.9 0.2 0.026 14.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) VIT1 PF01988.14 GAO87263.1 - 0.29 10.5 4.3 0.084 12.3 0.2 2.1 2 1 1 3 3 3 0 VIT family KfrA_N PF11740.3 GAO87263.1 - 0.38 11.2 8.7 0.24 11.8 1.1 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term SH3_9 PF14604.1 GAO87264.1 - 2.8e-07 30.0 0.4 5.6e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-RING_2 PF13639.1 GAO87264.1 - 3.2e-06 26.8 1.8 3.2e-06 26.8 1.3 3.9 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 GAO87264.1 - 8.2e-06 25.4 1.0 8.2e-06 25.4 0.7 5.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO87264.1 - 2.8e-05 23.7 0.6 2.8e-05 23.7 0.4 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO87264.1 - 0.00026 20.9 1.4 0.00026 20.9 1.0 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.23 GAO87264.1 - 0.00064 19.0 0.5 0.0015 17.8 0.3 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_UBOX PF13445.1 GAO87264.1 - 0.0027 17.3 2.4 0.004 16.8 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Tmpp129 PF10272.4 GAO87264.1 - 0.098 11.3 3.4 0.19 10.4 2.4 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor SH3_2 PF07653.12 GAO87264.1 - 0.11 12.0 0.2 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Annexin PF00191.15 GAO87265.1 - 9.8e-63 207.9 2.8 1.2e-18 66.6 0.1 4.2 4 0 0 4 4 4 4 Annexin EBP PF05241.7 GAO87267.1 - 3.6e-67 225.1 6.9 4.2e-67 224.9 4.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Velvet PF11754.3 GAO87270.1 - 0.0024 17.5 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 Velvet factor p450 PF00067.17 GAO87271.1 - 2.1e-78 263.9 0.0 2.5e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 L31 PF09784.4 GAO87273.1 - 7.2e-48 160.9 1.7 8.1e-48 160.7 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 MADF_DNA_bdg PF10545.4 GAO87273.1 - 0.081 13.1 0.5 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Acyltransferase PF01553.16 GAO87274.1 - 2e-05 24.0 0.0 4.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase DEAD PF00270.24 GAO87275.1 - 1.9e-40 138.1 0.6 3e-40 137.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO87275.1 - 4.4e-22 77.7 0.1 1.6e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAO87275.1 - 0.00015 21.7 0.4 0.00057 19.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 GAO87275.1 - 0.022 12.8 0.0 0.03 12.3 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2782 PF11191.3 GAO87275.1 - 0.23 11.4 1.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) BTV_NS2 PF04514.7 GAO87277.1 - 0.025 13.4 0.6 0.039 12.8 0.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4200 PF13863.1 GAO87277.1 - 0.032 14.1 1.4 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 GAO87277.1 - 8.5 5.9 15.4 2.4 7.7 3.2 2.4 2 0 0 2 2 2 0 IncA protein Nucleoplasmin PF03066.10 GAO87279.1 - 0.098 12.1 1.9 0.21 11.1 1.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin tRNA-synt_1d PF00750.14 GAO87280.1 - 6.1e-81 271.9 9.3 2.4e-44 151.6 4.2 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (R) DALR_1 PF05746.10 GAO87280.1 - 1.8e-27 95.6 0.1 1.8e-27 95.6 0.0 2.0 2 0 0 2 2 1 1 DALR anticodon binding domain ABC2_membrane PF01061.19 GAO87280.1 - 5e-27 94.4 30.4 7.8e-27 93.8 21.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAO87280.1 - 1.1e-24 87.2 0.1 1.1e-24 87.2 0.1 2.3 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.1 GAO87280.1 - 8.8e-06 25.8 0.1 2.2e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 GAO87280.1 - 9.2e-06 25.8 4.1 0.033 14.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain Arg_tRNA_synt_N PF03485.11 GAO87280.1 - 8e-05 23.1 0.4 0.00058 20.3 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF258 PF03193.11 GAO87280.1 - 0.00024 20.3 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAO87280.1 - 0.0011 18.9 0.2 0.003 17.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO87280.1 - 0.0012 18.2 0.3 0.0037 16.7 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAO87280.1 - 0.0027 18.5 3.4 0.0074 17.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO87280.1 - 0.003 17.4 0.1 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAO87280.1 - 0.0033 16.7 0.0 0.0087 15.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAO87280.1 - 0.0035 17.4 0.2 0.016 15.3 0.1 2.3 2 1 0 2 2 1 1 AAA domain MobB PF03205.9 GAO87280.1 - 0.0056 16.3 0.1 0.02 14.5 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAO87280.1 - 0.0069 16.0 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 GAO87280.1 - 0.0078 16.4 0.2 0.03 14.5 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAO87280.1 - 0.012 15.3 0.2 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAO87280.1 - 0.014 14.8 0.1 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 GAO87280.1 - 0.016 13.9 0.3 0.035 12.8 0.1 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 GAO87280.1 - 0.018 15.3 1.9 0.052 13.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 GAO87280.1 - 0.021 14.3 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 GAO87280.1 - 0.027 13.3 0.1 0.76 8.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 GAO87280.1 - 0.028 14.1 1.1 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 GAO87280.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 GAO87280.1 - 0.074 12.7 0.7 0.72 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 GAO87280.1 - 0.078 12.5 0.1 0.41 10.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAO87280.1 - 0.086 12.3 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 GAO87280.1 - 0.092 12.2 0.1 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAO87280.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 GAO87280.1 - 0.11 12.1 0.2 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 GAO87280.1 - 0.87 9.8 7.2 1.8 8.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAO87280.1 - 0.87 8.5 6.0 2 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain PIP5K PF01504.13 GAO87281.1 - 1.1e-28 100.0 0.0 1.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FAD_binding_6 PF00970.19 GAO87282.1 - 2.4e-30 104.5 0.0 3.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAO87282.1 - 2e-27 95.8 0.0 3.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAO87282.1 - 1.1e-06 28.7 0.0 9.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAO87282.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 GAO87282.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.3 GAO87283.1 - 1.6e-54 184.0 0.0 2.6e-54 183.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.14 GAO87284.1 - 1.6e-72 243.2 1.0 2.7e-72 242.5 0.7 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAO87284.1 - 4.7e-34 116.9 0.1 3.2e-33 114.2 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAO87284.1 - 1.6e-17 64.4 4.9 2.8e-09 37.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 GAO87284.1 - 3.6e-14 53.5 21.1 3.6e-14 53.5 14.7 6.8 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.1 GAO87284.1 - 1.7e-08 33.9 6.8 1.7e-08 33.9 4.7 3.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 GAO87284.1 - 0.00034 20.0 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 GAO87284.1 - 0.0014 17.7 11.7 0.0014 17.7 8.1 7.4 2 2 4 7 7 7 3 Autophagy protein Apg6 Reo_sigmaC PF04582.7 GAO87284.1 - 0.047 12.8 30.3 0.37 9.9 0.7 5.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 GAO87284.1 - 0.3 9.5 0.0 0.3 9.5 0.0 6.8 3 2 5 8 8 8 0 AAA domain DUF869 PF05911.6 GAO87284.1 - 4.5 5.3 91.3 0.28 9.3 22.0 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 GAO87284.1 - 6.3 6.5 101.2 0.034 13.9 3.5 6.6 3 2 2 6 6 6 0 Autophagy protein 16 (ATG16) RIO1 PF01163.17 GAO87285.1 - 1.5e-75 252.7 0.4 1.5e-75 252.7 0.3 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 GAO87285.1 - 2.3e-05 24.2 0.1 0.023 14.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAO87285.1 - 0.006 15.6 0.2 2.7 7.0 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family BACK PF07707.10 GAO87285.1 - 0.039 13.7 0.4 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 BTB And C-terminal Kelch APG17 PF04108.7 GAO87286.1 - 1.1e-148 495.4 0.0 1.3e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Tweety PF04906.8 GAO87286.1 - 0.17 10.3 0.2 0.7 8.2 0.1 2.0 2 0 0 2 2 2 0 Tweety DUF2365 PF10157.4 GAO87286.1 - 0.4 10.5 4.7 0.17 11.7 0.1 2.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2365) WD40 PF00400.27 GAO87287.1 - 8.7e-60 196.6 27.2 8.2e-10 38.1 0.0 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 GAO87287.1 - 1.3e-14 53.6 0.8 3e-14 52.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO87287.1 - 1.4e-11 43.7 0.2 3.3e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 GAO87287.1 - 1.2e-08 33.6 13.6 0.0081 14.3 0.2 6.0 3 3 3 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO87287.1 - 0.0031 16.3 0.5 1.3 7.7 0.0 2.7 2 1 1 3 3 3 2 Nup133 N terminal like PRANC PF09372.5 GAO87287.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 PRANC domain UCH PF00443.24 GAO87288.1 - 6.4e-77 258.2 0.0 1.7e-76 256.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAO87288.1 - 1e-15 57.9 0.0 4.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.1 GAO87288.1 - 2.9e-14 53.2 0.0 4.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 GAO87288.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Zn_clus PF00172.13 GAO87288.1 - 0.32 10.9 30.3 0.015 15.1 3.6 3.7 4 0 0 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 GAO87290.1 - 1.6e-34 119.3 0.3 2.3e-34 118.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PX PF00787.19 GAO87291.1 - 2.7e-18 65.8 0.0 8.6e-18 64.1 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 GAO87291.1 - 3.7e-09 36.2 10.2 1.7e-05 24.1 1.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Noggin PF05806.7 GAO87291.1 - 0.18 11.0 0.0 0.66 9.2 0.1 1.8 2 0 0 2 2 2 0 Noggin DUF2428 PF10350.4 GAO87292.1 - 4e-85 284.9 0.0 7.5e-84 280.7 0.0 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 GAO87292.1 - 0.00057 19.7 3.8 5.9 7.2 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 GAO87292.1 - 0.0016 18.8 0.2 0.077 13.5 0.0 3.7 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.1 GAO87292.1 - 0.31 11.3 8.5 0.73 10.1 0.0 4.5 5 0 0 5 5 5 0 HEAT repeats Tim17 PF02466.14 GAO87293.1 - 1.4e-27 96.2 4.2 1.7e-27 96.0 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 GAO87294.1 - 1.2e-48 165.5 0.0 3.9e-48 163.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87294.1 - 4.6e-25 88.1 0.0 7.4e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87294.1 - 0.0061 15.5 0.1 0.027 13.4 0.0 2.1 2 1 0 2 2 2 1 Kinase-like ILVD_EDD PF00920.16 GAO87295.1 - 6.8e-204 678.1 0.5 8e-204 677.8 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 GAO87295.1 - 0.092 12.7 0.1 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 5'-nucleotidase, C-terminal domain Acyltransferase PF01553.16 GAO87296.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase MFS_1 PF07690.11 GAO87297.1 - 1.1e-15 57.2 21.9 1.1e-15 57.2 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP1_TM PF14812.1 GAO87297.1 - 0.0023 18.1 0.5 0.0023 18.1 0.3 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4381 PF14316.1 GAO87297.1 - 0.028 14.5 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RAI16-like PF10257.4 GAO87298.1 - 5e-93 311.8 0.1 1.3e-92 310.5 0.0 1.7 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.18 GAO87299.1 - 1.9e-15 56.6 2.0 2.9e-15 56.0 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO87299.1 - 2.3e-07 30.8 0.8 3.4e-07 30.2 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Prp31_C PF09785.4 GAO87299.1 - 3.5 8.0 5.2 3.7 7.9 2.7 1.6 2 0 0 2 2 2 0 Prp31 C terminal domain zf-C3HC4_3 PF13920.1 GAO87300.1 - 0.0018 17.8 11.7 0.0031 17.1 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAO87300.1 - 0.69 9.7 6.6 1.2 8.9 4.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 GAO87300.1 - 2.2 8.3 13.3 3.6 7.6 9.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO87300.1 - 6.5 6.5 12.6 10 5.9 8.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF1900 PF08954.6 GAO87301.1 - 8.9e-49 164.5 0.0 1.8e-47 160.2 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 GAO87301.1 - 9.6e-35 118.0 0.0 1.8e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 GAO87301.1 - 6.6e-24 82.8 2.1 6.1e-07 29.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 GAO87301.1 - 0.00076 17.7 0.1 0.18 9.8 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 GAO87301.1 - 0.13 11.8 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.18 GAO87302.1 - 2.4e-104 348.6 0.6 2.4e-104 348.6 0.4 2.1 3 0 0 3 3 3 1 Kinesin motor domain Laminin_II PF06009.7 GAO87302.1 - 0.0054 16.4 4.4 0.0054 16.4 3.1 4.1 2 1 0 3 3 3 2 Laminin Domain II T2SF PF00482.18 GAO87302.1 - 0.21 11.4 4.1 0.74 9.7 0.1 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F AAA_22 PF13401.1 GAO87302.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.3 2 1 1 3 3 3 0 AAA domain IF-2B PF01008.12 GAO87303.1 - 7.6e-18 64.4 0.1 1.4e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 GAO87303.1 - 4.2e-13 49.0 0.7 1.7e-12 47.1 0.1 2.0 1 1 1 2 2 2 1 NUDIX domain GFA PF04828.9 GAO87304.1 - 1.3e-18 66.6 0.1 1.3e-18 66.6 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme AAA_17 PF13207.1 GAO87305.1 - 2.9e-09 37.7 0.2 1.2e-08 35.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAO87305.1 - 2.2e-06 27.4 0.0 4.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 GAO87305.1 - 4e-06 27.1 0.3 5.3e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO87305.1 - 3.4e-05 23.5 0.1 8e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAO87305.1 - 0.00011 22.1 0.2 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAO87305.1 - 0.00017 21.0 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 GAO87305.1 - 0.00061 19.3 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 GAO87305.1 - 0.00083 18.5 0.8 0.0012 18.0 0.1 1.6 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 GAO87305.1 - 0.0009 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 GAO87305.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO87305.1 - 0.002 18.1 0.3 0.0037 17.2 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 GAO87305.1 - 0.0033 16.8 0.2 0.099 12.0 0.0 2.5 3 0 0 3 3 3 1 Thymidylate kinase AAA_22 PF13401.1 GAO87305.1 - 0.0036 17.4 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAO87305.1 - 0.0094 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_11 PF13086.1 GAO87305.1 - 0.011 15.3 0.0 0.03 13.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 GAO87305.1 - 0.025 14.2 0.1 0.058 13.0 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase ArgK PF03308.11 GAO87305.1 - 0.03 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF633 PF04816.7 GAO87305.1 - 0.035 13.4 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF633) AAA_30 PF13604.1 GAO87305.1 - 0.036 13.6 0.7 0.094 12.2 0.4 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 GAO87305.1 - 0.052 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 GAO87305.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 GAO87305.1 - 0.063 12.2 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 GAO87305.1 - 0.088 12.7 0.0 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAO87305.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 GAO87305.1 - 0.097 12.6 2.3 0.15 11.9 0.1 2.2 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.7 GAO87305.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 GAO87305.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAO87305.1 - 0.13 12.5 1.0 0.72 10.1 0.0 2.4 2 1 1 3 3 3 0 ABC transporter AAA_31 PF13614.1 GAO87305.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hemerythrin PF01814.18 GAO87306.1 - 5e-14 52.6 2.4 6.9e-14 52.1 1.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Syntaxin PF00804.20 GAO87306.1 - 0.097 12.8 0.2 4.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Syntaxin Con-6 PF10346.4 GAO87307.1 - 2e-28 97.4 4.3 6.8e-17 60.5 0.1 2.4 2 0 0 2 2 2 2 Conidiation protein 6 CHZ PF09649.5 GAO87308.1 - 0.25 10.5 0.1 0.25 10.5 0.1 1.8 2 0 0 2 2 2 0 Histone chaperone domain CHZ NmrA PF05368.8 GAO87309.1 - 2.6e-16 59.5 1.4 1.4e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 GAO87309.1 - 1.2e-06 28.6 0.6 5.9e-06 26.4 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO87309.1 - 6.1e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO87309.1 - 0.00018 21.4 0.2 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAO87309.1 - 0.00061 18.7 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAO87309.1 - 0.00097 18.6 1.0 0.0096 15.3 0.4 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAO87309.1 - 0.028 13.3 0.2 0.13 11.1 0.2 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAO87309.1 - 0.041 12.7 0.3 0.061 12.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAO87309.1 - 0.17 10.8 0.5 0.38 9.6 0.2 1.6 1 1 1 2 2 2 0 Saccharopine dehydrogenase bZIP_1 PF00170.16 GAO87310.1 - 9.5e-07 28.6 0.9 2.6e-06 27.2 0.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor AT_hook PF02178.14 GAO87310.1 - 0.012 15.2 2.2 0.012 15.2 1.5 2.5 2 0 0 2 2 2 0 AT hook motif PEMT PF04191.8 GAO87312.1 - 7.1e-10 38.9 0.4 3.3e-08 33.5 0.1 2.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 GAO87312.1 - 1.8e-07 31.2 0.0 3.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_23 PF13489.1 GAO87313.1 - 2.6e-17 63.0 0.0 4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87313.1 - 1.7e-14 54.0 0.0 3.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87313.1 - 7.2e-14 52.3 0.0 1e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87313.1 - 1.6e-13 50.9 0.0 8.5e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87313.1 - 8e-13 48.2 0.0 8.4e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87313.1 - 1.1e-06 28.6 0.2 2.5e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87313.1 - 1.8e-06 28.2 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAO87313.1 - 3.6e-05 23.2 0.0 0.00025 20.5 0.0 1.9 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 GAO87313.1 - 5.3e-05 22.0 0.0 0.18 10.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) MTS PF05175.9 GAO87313.1 - 0.00017 21.0 0.0 0.00063 19.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.15 GAO87313.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 GAO87313.1 - 0.00096 18.3 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 GAO87313.1 - 0.0013 17.6 0.0 0.004 16.0 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_16 PF10294.4 GAO87313.1 - 0.0014 18.1 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 GAO87313.1 - 0.047 12.3 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.1 GAO87313.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAO87313.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2235 PF09994.4 GAO87314.1 - 1.9e-88 296.4 0.0 2.4e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RPE65 PF03055.10 GAO87315.1 - 1.3e-115 386.7 0.0 1.5e-115 386.5 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zn_Tnp_IS91 PF14319.1 GAO87315.1 - 0.05 13.0 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain CCP_MauG PF03150.9 GAO87315.1 - 0.083 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cutinase PF01083.17 GAO87316.1 - 1.1e-43 149.1 4.4 1.6e-43 148.5 3.1 1.3 1 0 0 1 1 1 1 Cutinase Collagen PF01391.13 GAO87316.1 - 8.5e-05 22.0 5.1 0.00023 20.6 3.5 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Abhydrolase_5 PF12695.2 GAO87316.1 - 0.00027 20.7 0.7 0.00051 19.8 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 GAO87316.1 - 0.00036 20.0 0.5 0.00061 19.2 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 GAO87316.1 - 0.00041 19.9 0.4 0.0049 16.4 0.6 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAO87316.1 - 0.0037 16.7 0.1 0.0069 15.8 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_9 PF10081.4 GAO87316.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_6 PF12697.2 GAO87316.1 - 0.018 14.8 0.2 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 GAO87316.1 - 0.026 14.7 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 GAO87316.1 - 0.038 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) p450 PF00067.17 GAO87317.1 - 4e-26 91.5 0.0 1.8e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2191 PF09957.4 GAO87317.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) p450 PF00067.17 GAO87318.1 - 1.7e-25 89.4 0.0 2.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAO87320.1 - 2.9e-27 95.6 3.5 3.8e-27 95.2 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87320.1 - 4e-17 62.8 0.1 4.8e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87320.1 - 1.6e-10 40.9 2.1 2.5e-10 40.3 1.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO87320.1 - 6.1e-09 36.1 1.1 9.2e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAO87320.1 - 2.3e-06 26.9 0.0 0.00054 19.1 0.0 2.5 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.8 GAO87320.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 GAO87320.1 - 0.017 14.0 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_4 PF01565.18 GAO87321.1 - 2.1e-28 98.5 2.5 7.8e-28 96.6 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO87321.1 - 0.0086 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 GAO87322.1 - 3.1e-25 88.2 3.5 2.7e-24 85.2 1.8 2.3 2 0 0 2 2 2 1 FAD binding domain DUF1353 PF07087.6 GAO87322.1 - 0.086 12.3 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Glyco_hydro_61 PF03443.9 GAO87323.1 - 9.1e-52 176.0 0.0 9.1e-52 176.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Beta_helix PF13229.1 GAO87323.1 - 0.19 11.4 18.4 0.44 10.3 11.8 2.0 2 0 0 2 2 2 0 Right handed beta helix region Hamartin PF04388.7 GAO87323.1 - 0.59 8.7 8.5 0.76 8.3 5.9 1.1 1 0 0 1 1 1 0 Hamartin protein TSGP1 PF07771.6 GAO87323.1 - 0.65 9.8 9.4 1.7 8.5 2.6 2.5 2 0 0 2 2 2 0 Tick salivary peptide group 1 Pentapeptide_2 PF01469.13 GAO87323.1 - 1.7 8.3 23.7 1.6 8.4 6.5 2.7 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) TFIIA PF03153.8 GAO87323.1 - 2.4 7.9 9.6 3.3 7.5 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.23 GAO87324.1 - 1.2e-249 827.6 0.1 1.7e-83 280.3 0.0 3.5 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 GAO87324.1 - 6.1e-158 524.3 0.2 9.5e-45 152.7 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 GAO87324.1 - 5.5e-31 106.6 1.3 3.9e-10 39.8 0.0 4.5 5 0 0 5 5 5 3 Phosphopantetheine attachment site p450 PF00067.17 GAO87325.1 - 9.5e-59 199.1 0.0 1.3e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 GAO87326.1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87326.1 - 9.1e-05 22.0 0.0 0.00034 20.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87326.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 GAO87326.1 - 0.022 14.7 0.1 0.28 11.1 0.0 2.1 1 1 0 2 2 2 0 FtsJ-like methyltransferase DUF3433 PF11915.3 GAO87327.1 - 3.5e-48 161.6 17.1 6.7e-25 87.0 2.9 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) ApbA PF02558.11 GAO87327.1 - 2.4e-29 101.7 0.0 4.5e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAO87327.1 - 1.5e-28 99.3 0.0 3.3e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NQRA PF05896.6 GAO87327.1 - 0.33 10.1 0.0 0.69 9.0 0.0 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Glyco_hydro_2_N PF02837.13 GAO87328.1 - 2.1e-26 92.4 0.0 3.8e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAO87328.1 - 2.9e-13 49.4 0.0 6.4e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAO87328.1 - 1.4e-09 38.3 0.0 1.6e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAO87328.1 - 0.0089 16.2 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain SMP PF04927.7 GAO87329.1 - 5.7e-05 22.9 0.6 0.00012 21.9 0.4 1.5 1 0 0 1 1 1 1 Seed maturation protein Abhydrolase_2 PF02230.11 GAO87330.1 - 0.00044 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAO87330.1 - 0.0028 16.8 0.1 0.054 12.7 0.2 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAO87330.1 - 0.0029 16.8 0.1 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 GAO87330.1 - 0.0042 16.5 0.2 0.0094 15.4 0.1 1.4 1 1 0 1 1 1 1 Putative esterase Glyco_hydro_61 PF03443.9 GAO87331.1 - 1e-43 149.6 0.1 1.5e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 GAO87332.1 - 1.6e-45 155.3 21.6 1.6e-45 155.3 15.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box PF00646.28 GAO87333.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain DHDPS PF00701.17 GAO87334.1 - 1e-44 152.2 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ATP-synt_E PF05680.7 GAO87334.1 - 0.082 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 ATP synthase E chain Cation_efflux PF01545.16 GAO87335.1 - 5.8e-82 274.9 0.4 1.3e-81 273.8 0.2 1.5 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 GAO87335.1 - 0.0064 15.5 11.1 0.095 11.6 7.7 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Dicty_CAR PF05462.6 GAO87335.1 - 0.034 13.0 1.0 0.057 12.3 0.7 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Metallophos PF00149.23 GAO87336.1 - 1.8e-10 40.5 0.0 3e-08 33.3 0.0 3.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3546 PF12066.3 GAO87336.1 - 0.12 12.3 1.6 0.66 10.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Sugar_tr PF00083.19 GAO87337.1 - 6.9e-126 420.4 27.5 8e-126 420.2 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO87337.1 - 2.3e-20 72.6 39.1 3.9e-14 52.1 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydro_lipase PF04083.11 GAO87338.1 - 1.7e-20 72.1 0.1 5.7e-20 70.4 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 GAO87338.1 - 1.6e-07 31.4 3.2 1.6e-07 31.4 2.2 1.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87338.1 - 0.00081 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metal_resist PF13801.1 GAO87338.1 - 0.011 15.7 0.4 0.03 14.3 0.3 1.8 1 0 0 1 1 1 0 Heavy-metal resistance Abhydrolase_1 PF00561.15 GAO87338.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cupin_1 PF00190.17 GAO87339.1 - 3.8e-29 100.9 0.1 2e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAO87339.1 - 2.8e-24 84.3 0.1 1.7e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAO87339.1 - 6.9e-09 34.9 0.0 0.0022 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 GAO87339.1 - 7.4e-07 28.9 0.1 3.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 GAO87339.1 - 1.5e-05 24.7 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 GAO87339.1 - 9.9e-05 21.9 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase FdtA PF05523.6 GAO87339.1 - 0.0026 17.2 0.0 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 WxcM-like, C-terminal 2OG-FeII_Oxy_5 PF13759.1 GAO87339.1 - 0.0037 17.5 0.2 26 5.1 0.0 3.7 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase 3-HAO PF06052.7 GAO87339.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 GAO87339.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.7 GAO87339.1 - 0.14 11.3 0.0 0.6 9.3 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Pentapeptide_4 PF13599.1 GAO87340.1 - 6e-09 35.5 0.1 0.0064 16.2 0.0 3.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) DUF2767 PF10965.3 GAO87340.1 - 0.03 14.1 0.1 0.1 12.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Pentapeptide PF00805.17 GAO87340.1 - 0.057 12.6 0.0 6.3 6.1 0.0 3.0 2 1 1 3 3 3 0 Pentapeptide repeats (8 copies) CfAFP PF05264.6 GAO87340.1 - 0.2 11.3 8.8 0.53 10.0 0.0 2.5 1 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Glyco_hydro_88 PF07470.8 GAO87341.1 - 1.2e-70 238.2 5.0 1.4e-70 238.0 3.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pkinase PF00069.20 GAO87342.1 - 5.6e-17 61.7 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87342.1 - 1.1e-07 31.1 0.0 4.3e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 GAO87343.1 - 1.2e-05 24.5 2.4 0.00049 19.2 1.7 2.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Rnk_N PF14760.1 GAO87343.1 - 0.093 12.8 0.1 0.34 11.0 0.1 2.0 1 0 0 1 1 1 0 Rnk N-terminus Hydrophobin PF01185.13 GAO87344.1 - 0.00039 20.8 5.9 0.001 19.4 3.6 1.9 1 1 1 2 2 2 2 Fungal hydrophobin eIF-3_zeta PF05091.7 GAO87345.1 - 2.2e-195 650.1 0.0 2.6e-195 649.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.16 GAO87346.1 - 0.0017 18.2 9.0 0.0034 17.2 5.9 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO87346.1 - 0.82 9.5 10.4 0.046 13.5 3.0 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF4187 PF13821.1 GAO87349.1 - 7.9e-25 86.2 0.4 2.1e-24 84.8 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 GAO87349.1 - 3.1e-24 85.1 0.4 3.1e-24 85.1 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 GAO87349.1 - 2e-10 41.2 0.1 7.5e-10 39.3 0.1 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.10 GAO87350.1 - 1.1e-30 105.8 4.1 2.3e-30 104.8 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 GAO87350.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Kinesin PF00225.18 GAO87351.1 - 1.3e-110 369.3 0.0 2.2e-110 368.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 GAO87351.1 - 4.7e-44 149.4 0.1 9.8e-44 148.4 0.1 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 GAO87351.1 - 6.1e-10 39.2 0.0 1.8e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 GAO87351.1 - 1.1e-07 31.7 0.3 3.1e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B Glyco_transf_90 PF05686.7 GAO87352.1 - 2e-32 112.3 0.1 3.1e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 GAO87352.1 - 7.7e-05 22.8 0.1 0.00015 21.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_43 PF04616.9 GAO87353.1 - 2.3e-33 115.5 0.0 3.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 GAO87353.1 - 0.011 15.1 0.6 0.51 9.6 0.0 2.6 2 1 1 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain BCS1_N PF08740.6 GAO87354.1 - 3.4e-63 212.6 0.0 6e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAO87354.1 - 2.7e-17 63.2 0.0 5e-16 59.1 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO87354.1 - 0.0021 18.0 1.1 0.0043 17.0 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAO87354.1 - 0.0029 18.4 0.0 0.013 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO87354.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAO87354.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 GAO87354.1 - 0.021 13.9 0.0 0.056 12.5 0.0 1.7 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 GAO87354.1 - 0.024 13.7 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 GAO87354.1 - 0.035 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAO87354.1 - 0.051 13.3 0.1 0.21 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAO87354.1 - 0.082 13.2 2.2 0.096 12.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 GAO87354.1 - 0.1 12.1 0.4 0.27 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAO87354.1 - 0.14 12.3 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Phosphodiest PF01663.17 GAO87355.1 - 1.9e-87 293.9 0.2 2.5e-87 293.5 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAO87355.1 - 0.00057 19.1 0.0 0.39 9.8 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 GAO87355.1 - 0.011 15.4 0.0 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Macoilin PF09726.4 GAO87356.1 - 3.1 5.9 11.6 4 5.6 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein HLH PF00010.21 GAO87358.1 - 2.6e-16 59.0 0.6 7.4e-16 57.5 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rootletin PF15035.1 GAO87358.1 - 0.05 13.5 6.0 0.088 12.7 4.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.13 GAO87358.1 - 0.23 11.4 1.1 0.39 10.7 0.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Phage_GPO PF05929.6 GAO87358.1 - 0.25 10.5 1.1 0.4 9.8 0.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HALZ PF02183.13 GAO87358.1 - 0.29 10.8 2.4 0.74 9.5 1.0 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ofd1_CTDD PF10637.4 GAO87359.1 - 3.5e-109 364.0 0.1 1.4e-102 342.4 0.1 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 GAO87359.1 - 2.5e-15 56.8 0.0 7.6e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAO87359.1 - 0.049 13.2 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Nucleoplasmin PF03066.10 GAO87359.1 - 0.77 9.2 9.3 4.4 6.8 1.4 2.5 2 0 0 2 2 2 0 Nucleoplasmin DUF3287 PF11690.3 GAO87361.1 - 0.096 12.7 0.9 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) GMC_oxred_N PF00732.14 GAO87362.1 - 9.1e-60 202.3 0.0 1.5e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO87362.1 - 3.7e-31 108.3 0.0 7.2e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase ECH PF00378.15 GAO87362.1 - 9e-18 64.2 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NAD_binding_8 PF13450.1 GAO87362.1 - 6.7e-05 22.8 1.0 0.00044 20.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAO87362.1 - 0.0005 19.0 0.2 0.00086 18.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAO87362.1 - 0.00074 18.5 1.4 0.0076 15.1 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO87362.1 - 0.0033 17.5 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO87362.1 - 0.0055 15.6 1.5 0.15 10.8 0.3 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 GAO87362.1 - 0.011 14.2 0.2 0.039 12.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 GAO87362.1 - 0.039 14.3 0.2 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO87362.1 - 0.075 12.1 0.2 0.18 10.8 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Abhydrolase_6 PF12697.2 GAO87363.1 - 9.4e-29 100.8 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO87363.1 - 1.5e-13 50.8 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO87363.1 - 1.2e-07 31.6 0.0 1.5e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO87363.1 - 4.7e-06 26.3 0.0 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAO87363.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family DinB_2 PF12867.2 GAO87364.1 - 0.14 12.5 0.5 0.25 11.7 0.4 1.5 1 0 0 1 1 1 0 DinB superfamily MRP-S31 PF15433.1 GAO87364.1 - 0.54 9.6 3.2 0.62 9.4 2.2 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TAFII55_N PF04658.8 GAO87365.1 - 1.7e-53 180.4 0.1 6.6e-53 178.5 0.0 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Bromo_TP PF07524.8 GAO87366.1 - 7.7e-09 35.1 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Sirohm_synth_C PF14823.1 GAO87366.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal BRO1 PF03097.13 GAO87367.1 - 9.7e-08 31.1 0.0 1.6e-07 30.4 0.0 1.3 2 0 0 2 2 2 1 BRO1-like domain NDUFB10 PF10249.4 GAO87368.1 - 0.0026 17.8 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Glyco_transf_34 PF05637.7 GAO87369.1 - 4.5e-67 226.0 0.3 6.5e-67 225.5 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SecG PF03840.9 GAO87369.1 - 0.1 12.3 0.3 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Pkinase PF00069.20 GAO87370.1 - 2e-69 233.6 0.0 3.5e-69 232.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87370.1 - 3.8e-35 121.1 0.0 5.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAO87370.1 - 2.1e-10 40.5 0.2 8.3e-10 38.6 0.1 2.1 2 0 0 2 2 2 1 FHA domain APH PF01636.18 GAO87370.1 - 0.00047 19.9 0.0 0.33 10.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO87370.1 - 0.0027 16.7 0.0 0.0066 15.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO87370.1 - 0.017 14.1 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beta_elim_lyase PF01212.16 GAO87371.1 - 2.3e-70 237.0 0.0 2.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 GAO87371.1 - 0.0099 14.4 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 GAO87371.1 - 0.092 11.0 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tropomyosin_1 PF12718.2 GAO87372.1 - 0.0026 17.6 0.8 0.029 14.2 0.1 2.4 2 0 0 2 2 2 1 Tropomyosin like Yippee-Mis18 PF03226.9 GAO87372.1 - 0.035 14.1 2.0 0.082 12.9 1.4 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RNase_T PF00929.19 GAO87373.1 - 2.7e-22 79.7 0.0 4.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.19 GAO87374.1 - 1.2e-18 66.8 0.0 4.5e-17 61.7 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 GAO87374.1 - 5e-14 51.8 0.0 3.5e-13 49.1 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 GAO87374.1 - 7.3e-06 26.0 0.0 0.0015 18.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like TrbC_Ftype PF09673.5 GAO87374.1 - 0.0042 16.6 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 3 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 GAO87374.1 - 0.024 14.8 0.0 1.3 9.2 0.0 3.2 2 2 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 GAO87374.1 - 0.042 13.6 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain ArsC PF03960.10 GAO87374.1 - 0.17 11.9 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 ArsC family TauD PF02668.11 GAO87375.1 - 3.6e-56 190.6 0.6 5.1e-56 190.2 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAO87375.1 - 0.003 16.5 0.3 0.0066 15.3 0.2 1.5 1 1 0 1 1 1 1 CsiD DUF971 PF06155.7 GAO87375.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 GAO87375.1 - 0.038 14.5 0.0 0.096 13.2 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.22 GAO87376.1 - 5.5e-67 221.5 1.0 6.2e-22 77.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Auts2 PF15336.1 GAO87376.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein HMD PF03201.11 GAO87376.1 - 0.038 13.9 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Tubulin PF00091.20 GAO87377.1 - 1.8e-66 224.0 0.0 2.3e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAO87377.1 - 3.7e-44 149.7 0.0 5.8e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAO87377.1 - 4e-05 23.1 0.0 8.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.13 GAO87378.1 - 9.6e-25 87.1 1.7 1.8e-24 86.2 1.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAO87378.1 - 0.00028 19.9 0.3 0.00072 18.6 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAO87378.1 - 0.00088 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAO87378.1 - 0.0011 18.1 0.0 0.0027 16.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAO87378.1 - 0.002 18.2 1.8 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair DUF2648 PF10855.3 GAO87378.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Pkinase PF00069.20 GAO87379.1 - 7.3e-61 205.5 0.0 2.6e-39 134.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87379.1 - 1.9e-28 99.2 0.0 1.5e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 GAO87379.1 - 4e-12 46.1 0.0 9.2e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 GAO87379.1 - 2.9e-08 33.0 0.3 7e-06 25.1 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 GAO87379.1 - 3.5e-06 26.9 0.0 0.0033 17.1 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 GAO87379.1 - 0.00056 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold Kdo PF06293.9 GAO87379.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.5 GAO87379.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 GAO87379.1 - 0.0087 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain Seadorna_VP7 PF07387.6 GAO87379.1 - 0.11 11.2 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 GMC_oxred_N PF00732.14 GAO87380.1 - 1.7e-36 125.8 0.0 2.8e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO87380.1 - 1.9e-35 122.2 0.2 3.3e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAO87380.1 - 6.9e-09 35.0 0.4 3.2e-08 32.8 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO87380.1 - 4.9e-07 28.9 1.2 3.2e-06 26.2 0.8 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO87380.1 - 6.4e-05 22.9 0.2 0.00012 22.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO87380.1 - 7.7e-05 21.7 0.1 0.00013 20.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAO87380.1 - 0.00078 19.4 2.1 0.0014 18.6 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO87380.1 - 0.0022 16.5 0.1 0.0038 15.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAO87380.1 - 0.0045 16.1 0.1 0.008 15.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAO87380.1 - 0.0099 15.9 0.7 0.24 11.4 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO87380.1 - 0.013 14.6 1.4 0.022 13.8 1.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAO87380.1 - 0.017 14.0 0.7 0.029 13.2 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO87380.1 - 0.026 13.1 0.5 0.038 12.6 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 GAO87380.1 - 0.031 14.6 0.3 0.092 13.1 0.3 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NUMOD1 PF07453.8 GAO87381.1 - 0.0076 16.0 0.1 1.3 8.9 0.0 2.2 1 1 1 2 2 2 2 NUMOD1 domain 3Beta_HSD PF01073.14 GAO87382.1 - 2.1e-47 161.1 0.0 1.1e-46 158.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO87382.1 - 2.5e-22 79.4 0.0 5e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO87382.1 - 6.9e-16 57.9 0.0 1.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 GAO87382.1 - 2.3e-09 36.5 0.0 1.6e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAO87382.1 - 5.1e-05 23.3 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO87382.1 - 0.0066 15.3 0.0 0.075 11.9 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 GAO87382.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 GAO87382.1 - 0.12 12.2 0.1 10 5.9 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase UQ_con PF00179.21 GAO87383.1 - 2.2e-30 104.9 0.0 9.2e-12 44.5 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO87383.1 - 0.0004 20.1 0.0 0.01 15.5 0.0 2.9 2 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 GAO87383.1 - 0.018 14.9 0.0 2 8.3 0.0 2.5 2 1 0 2 2 2 0 RWD domain UEV PF05743.8 GAO87383.1 - 0.053 13.2 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 UEV domain RhoGAP PF00620.22 GAO87384.1 - 1.1e-36 125.7 0.3 2.1e-36 124.8 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAO87384.1 - 4.6e-30 103.4 40.2 5.1e-12 45.6 4.5 4.8 5 0 0 5 5 5 4 LIM domain Tri3 PF07428.6 GAO87384.1 - 0.076 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Desulfoferrod_N PF06397.7 GAO87384.1 - 0.23 10.8 2.9 0.22 10.9 0.3 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Nbl1_Borealin_N PF10444.4 GAO87385.1 - 1.6e-20 72.1 4.9 2.8e-20 71.4 3.4 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 GAO87386.1 - 1.7e-11 44.5 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 GAO87386.1 - 3.7e-05 23.3 0.1 5.4e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 GAO87386.1 - 0.0031 16.9 0.6 0.011 15.1 0.4 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA PF00092.23 GAO87386.1 - 0.0065 16.2 0.3 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4097 PF13349.1 GAO87386.1 - 0.073 12.6 0.2 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DUF2011 PF09428.5 GAO87386.1 - 7.4 6.4 9.7 18 5.1 0.1 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Sybindin PF04099.7 GAO87387.1 - 1.3e-45 154.6 0.0 1.5e-44 151.1 0.0 2.0 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAO87387.1 - 3e-07 30.3 0.0 6.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CmcI PF04989.7 GAO87387.1 - 0.0088 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase ArsB PF02040.10 GAO87388.1 - 3e-15 56.1 16.7 1.3e-08 34.2 4.0 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein zf-C2H2_4 PF13894.1 GAO87390.1 - 0.016 15.5 1.4 0.016 15.5 1.0 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO87390.1 - 1.7 9.1 18.7 0.97 9.9 1.0 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type ABC2_membrane PF01061.19 GAO87391.1 - 7.7e-96 319.2 57.7 1.6e-49 167.9 15.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO87391.1 - 3.3e-37 126.2 11.0 2.2e-34 117.1 0.0 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 GAO87391.1 - 3e-35 121.5 0.0 9.3e-17 61.6 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 GAO87391.1 - 1e-24 86.3 0.0 2.6e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO87391.1 - 3.7e-06 26.4 0.0 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAO87391.1 - 0.00053 19.2 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAO87391.1 - 0.0014 18.5 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAO87391.1 - 0.0015 17.9 1.0 0.012 15.0 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 GAO87391.1 - 0.0025 16.9 52.0 0.015 14.3 17.8 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 GAO87391.1 - 0.0052 16.2 0.3 0.57 9.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 GAO87391.1 - 0.01 15.0 0.0 0.78 8.9 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAO87391.1 - 0.013 15.5 0.2 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAO87391.1 - 0.022 14.9 0.1 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAO87391.1 - 0.026 14.0 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAO87391.1 - 0.043 14.1 0.0 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3220 PF11516.3 GAO87391.1 - 0.085 12.8 0.0 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Miro PF08477.8 GAO87391.1 - 0.086 13.3 0.0 25 5.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 GAO87391.1 - 0.29 10.7 2.7 12 5.4 0.0 2.9 3 0 0 3 3 3 0 NACHT domain MFS_1 PF07690.11 GAO87392.1 - 2.6e-37 128.3 46.8 5e-36 124.1 32.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87392.1 - 4.2e-16 58.5 22.4 2.8e-13 49.2 8.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAO87392.1 - 1.3e-08 33.4 14.2 1.7e-08 33.1 9.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.1 GAO87393.1 - 9.3e-45 152.9 52.0 1.2e-44 152.5 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO87393.1 - 4.3e-26 91.2 46.7 5.7e-26 90.8 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Alpha-L-AF_C PF06964.7 GAO87394.1 - 5.6e-36 123.9 0.3 1.1e-35 123.0 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Big_4 PF07532.6 GAO87394.1 - 0.056 12.9 0.4 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) zf-C2H2_4 PF13894.1 GAO87395.1 - 0.34 11.3 2.2 1 9.8 1.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger SH3BGR PF04908.10 GAO87396.1 - 0.00079 19.3 0.0 0.0029 17.5 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Remorin_N PF03766.8 GAO87396.1 - 0.016 14.9 1.2 0.016 14.9 0.9 2.2 2 1 0 2 2 2 0 Remorin, N-terminal region DDHD PF02862.12 GAO87396.1 - 1.9 8.2 11.4 0.3 10.8 1.6 2.2 2 0 0 2 2 2 0 DDHD domain CAP_N PF01213.14 GAO87396.1 - 2.3 7.4 7.5 4.2 6.5 5.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribul_P_3_epim PF00834.14 GAO87397.1 - 9.8e-62 207.6 0.0 1.9e-60 203.4 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 GAO87397.1 - 0.056 12.5 0.1 0.076 12.0 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 GAO87397.1 - 0.077 12.3 0.2 0.083 12.2 0.1 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 GAO87397.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Methyltransf_11 PF08241.7 GAO87398.1 - 2.7e-06 27.7 0.0 5.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87398.1 - 0.0027 17.4 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87398.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 GAO87399.1 - 5e-16 58.0 0.7 6.8e-16 57.5 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAO87399.1 - 0.022 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 GAO87399.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DRMBL PF07522.9 GAO87400.1 - 8.1e-35 119.1 0.0 1.5e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAO87400.1 - 7.2e-12 45.2 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rad50_zn_hook PF04423.9 GAO87400.1 - 0.1 12.0 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif p450 PF00067.17 GAO87401.1 - 1.8e-107 359.7 0.0 2.1e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.10 GAO87402.1 - 4.5e-183 610.0 51.1 5.2e-183 609.8 35.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.6 GAO87402.1 - 0.12 12.3 8.0 0.35 10.8 2.7 3.0 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA E1-E2_ATPase PF00122.15 GAO87402.1 - 1.2 8.1 3.8 1.8 7.5 0.2 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Fungal_trans PF04082.13 GAO87403.1 - 3.2e-06 26.1 1.0 5.1e-06 25.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vint PF14623.1 GAO87403.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Hint-domain SMP PF04927.7 GAO87404.1 - 2.2e-18 65.9 16.6 4.4e-06 26.5 0.4 3.1 2 1 1 3 3 3 3 Seed maturation protein T4_deiodinase PF00837.12 GAO87405.1 - 0.069 12.1 0.0 9.2 5.1 0.0 2.1 2 0 0 2 2 2 0 Iodothyronine deiodinase GFA PF04828.9 GAO87406.1 - 3.3e-23 81.4 0.0 4.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 GAO87406.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.2 GAO87406.1 - 0.45 10.3 3.4 0.57 10.0 1.0 2.2 2 1 0 2 2 2 0 Double zinc ribbon Citrate_synt PF00285.16 GAO87407.1 - 1.8e-83 280.1 0.0 2.1e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase MFS_1 PF07690.11 GAO87408.1 - 1.7e-42 145.3 27.5 2.9e-42 144.6 19.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PBP PF01161.15 GAO87408.1 - 5.6e-10 39.2 0.1 9.9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sugar_tr PF00083.19 GAO87408.1 - 5.9e-10 38.3 10.8 5.9e-10 38.3 7.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO87408.1 - 8e-05 21.0 5.8 8e-05 21.0 4.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTPA PF03095.10 GAO87409.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein PBP PF01161.15 GAO87410.1 - 2.2e-24 85.9 0.0 2.8e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATG22 PF11700.3 GAO87411.1 - 1.3e-187 624.0 14.4 1.5e-187 623.8 10.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAO87411.1 - 0.0021 16.8 53.8 0.12 11.0 6.8 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF423 PF04241.10 GAO87411.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF423) Gln-synt_C PF00120.19 GAO87413.1 - 2.4e-43 148.1 0.0 3.1e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Sugar_tr PF00083.19 GAO87414.1 - 2.9e-87 293.1 33.6 3.3e-87 292.9 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO87414.1 - 6.5e-21 74.4 75.5 5.5e-20 71.3 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO87414.1 - 1.3e-06 26.9 5.7 1.3e-06 26.9 4.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAO87414.1 - 0.00059 18.3 3.6 0.00059 18.3 2.5 3.2 2 2 0 2 2 2 1 MFS/sugar transport protein Mem_trans PF03547.13 GAO87414.1 - 0.0012 17.1 5.8 0.0012 17.1 4.1 2.4 3 1 1 4 4 4 1 Membrane transport protein adh_short PF00106.20 GAO87416.1 - 5.8e-29 101.1 0.3 7.1e-29 100.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87416.1 - 6e-29 101.5 0.0 6.8e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87416.1 - 1.5e-14 54.0 0.1 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Aa_trans PF01490.13 GAO87419.1 - 2.9e-37 128.1 25.8 3.5e-37 127.8 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 GAO87419.1 - 0.043 13.4 0.1 0.043 13.4 0.1 3.6 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1129 PF06570.6 GAO87419.1 - 7.3 5.8 17.7 0.12 11.6 1.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) F-box-like PF12937.2 GAO87420.1 - 0.0045 16.6 0.1 0.0096 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like Hexose_dehydrat PF03559.9 GAO87420.1 - 0.013 14.5 0.3 0.02 13.9 0.2 1.3 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase TPR_11 PF13414.1 GAO87421.1 - 1.7e-13 49.9 6.5 8e-07 28.6 0.0 4.8 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.12 GAO87421.1 - 2.2e-11 42.7 11.2 0.00015 21.4 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAO87421.1 - 9.7e-11 40.8 7.7 0.00019 20.8 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAO87421.1 - 2e-09 37.2 8.2 0.0061 16.4 0.1 5.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO87421.1 - 5.3e-07 28.9 0.9 2 8.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO87421.1 - 6.2e-07 29.9 20.2 0.021 15.5 0.3 7.4 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAO87421.1 - 2.6e-05 24.4 9.4 0.41 11.0 0.3 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAO87421.1 - 0.00017 21.5 8.4 11 6.5 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO87421.1 - 0.00057 20.2 13.9 9.7 7.1 0.1 7.7 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAO87421.1 - 0.0062 16.8 10.2 4.2 8.0 0.1 5.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO87421.1 - 0.013 15.2 5.3 31 4.7 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAO87421.1 - 0.069 13.0 7.8 0.42 10.4 0.0 4.8 7 0 0 7 7 7 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 GAO87422.1 - 7.4e-71 239.0 0.0 9.9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF866 PF05907.8 GAO87422.1 - 2.8e-43 147.2 0.5 4.9e-43 146.3 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Phe_hydrox_dim PF07976.7 GAO87422.1 - 3.6e-41 140.5 0.0 6.1e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain LSM PF01423.17 GAO87422.1 - 4.6e-16 58.1 0.1 1e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 LSM domain Pyr_redox PF00070.22 GAO87422.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO87422.1 - 0.02 13.8 0.0 0.045 12.6 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO87422.1 - 0.036 12.9 0.0 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 GAO87422.1 - 0.052 11.8 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.11 GAO87422.1 - 0.17 11.3 0.0 0.78 9.1 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DDHD PF02862.12 GAO87424.1 - 1.1e-45 156.2 0.0 5.9e-27 94.9 0.0 2.5 1 1 1 2 2 2 2 DDHD domain Abhydrolase_5 PF12695.2 GAO87424.1 - 0.036 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.19 GAO87425.1 - 4.2e-48 162.4 0.0 1.2e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 GAO87425.1 - 4.9e-34 117.0 0.5 7.1e-34 116.4 0.3 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAO87425.1 - 7.8e-18 64.2 0.1 1.9e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 GAO87425.1 - 2 7.7 13.2 3 7.1 9.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.2 GAO87425.1 - 3.4 6.7 15.1 5.4 6.1 10.4 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family ATP-synt_C PF00137.16 GAO87426.1 - 9e-27 92.7 30.2 8.1e-18 64.0 5.2 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 GAO87426.1 - 0.2 11.2 7.2 0.4 10.2 2.5 2.8 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.17 GAO87427.1 - 2.2e-59 199.4 0.2 2.8e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO87427.1 - 7.5e-21 74.8 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO87427.1 - 1.2e-17 63.7 0.1 1.4e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO87427.1 - 2.1e-07 30.5 0.0 9.9e-07 28.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAO87427.1 - 3.8e-06 26.2 0.1 4.5e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAO87427.1 - 5e-06 25.8 0.0 8.1e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAO87427.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO87427.1 - 0.025 14.4 0.1 2.8 7.7 0.0 2.4 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 GAO87427.1 - 0.042 13.7 0.1 0.09 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO87427.1 - 0.11 12.5 0.0 1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain Kei1 PF08552.6 GAO87428.1 - 1.8e-62 210.3 3.5 2.2e-62 210.0 2.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 GAO87429.1 - 2.4e-51 173.2 0.0 1.1e-43 148.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 GAO87429.1 - 6.3e-30 102.6 0.0 8e-14 51.0 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 GAO87429.1 - 1.9e-27 96.0 0.0 5.4e-27 94.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.14 GAO87429.1 - 2.5e-07 30.4 1.4 4.2e-06 26.4 0.0 2.8 2 1 1 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3181 PF11378.3 GAO87429.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Sin_N PF04801.8 GAO87430.1 - 2.8e-25 89.0 1.4 2.7e-24 85.8 1.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.14 GAO87431.1 - 2.3e-172 573.0 0.0 3.1e-172 572.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 GAO87431.1 - 3.3e-80 269.7 0.2 5.9e-80 268.8 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 GAO87431.1 - 0.04 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family Med26 PF08711.6 GAO87431.1 - 0.073 12.5 0.1 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Fungal_trans PF04082.13 GAO87432.1 - 3.2e-36 124.5 0.0 5.5e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87432.1 - 1e-09 38.1 8.9 1.8e-09 37.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO87432.1 - 0.016 13.8 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Radical_SAM PF04055.16 GAO87433.1 - 3.6e-10 40.2 0.0 5.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAO87433.1 - 1.2e-06 28.7 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAO87433.1 - 0.0006 19.8 0.1 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF92 PF01940.11 GAO87434.1 - 1.1e-62 211.1 10.8 1.5e-62 210.7 7.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Methyltransf_33 PF10017.4 GAO87435.1 - 2.6e-28 98.4 0.0 5.6e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 GAO87435.1 - 9.1e-22 77.6 3.7 2.3e-10 40.2 0.6 2.3 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 GAO87435.1 - 3.5e-09 37.0 0.6 1.2e-08 35.3 0.4 2.0 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 GAO87435.1 - 1.5e-05 25.2 0.0 6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87435.1 - 4e-05 23.3 0.0 0.0025 17.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain DUF2020 PF09449.5 GAO87435.1 - 0.033 13.8 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Aldedh PF00171.17 GAO87436.1 - 7.9e-137 456.3 0.1 8.9e-137 456.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO87436.1 - 7e-07 28.2 0.1 5.5e-06 25.3 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) TFIIA_gamma_N PF02268.11 GAO87438.1 - 5.5e-25 86.6 0.3 9.9e-25 85.8 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 GAO87438.1 - 2.8e-22 78.2 2.7 5.5e-22 77.3 1.9 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Baculo_19 PF04798.7 GAO87438.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Hexokinase_2 PF03727.11 GAO87440.1 - 2e-29 102.5 0.0 5.9e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 GAO87440.1 - 4.2e-26 91.5 0.0 1.7e-24 86.2 0.0 2.8 1 1 0 1 1 1 1 Hexokinase DUF4209 PF13910.1 GAO87440.1 - 0.029 14.4 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) GILT PF03227.11 GAO87441.1 - 9.6e-08 31.8 0.1 1.8e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DNA_pol3_beta PF00712.14 GAO87442.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain MFS_1 PF07690.11 GAO87443.1 - 7.3e-36 123.5 22.0 7.3e-36 123.5 15.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO87443.1 - 0.096 12.4 7.1 1.4 8.7 0.2 3.1 2 1 1 3 3 3 0 MFS_1 like family PHO4 PF01384.15 GAO87443.1 - 5.6 5.5 8.6 0.066 11.8 0.5 1.8 2 0 0 2 2 2 0 Phosphate transporter family adh_short PF00106.20 GAO87444.1 - 5.9e-27 94.6 1.2 8.7e-27 94.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87444.1 - 1.4e-25 90.4 0.1 1.7e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87444.1 - 1e-14 54.6 0.4 1.6e-14 54.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO87444.1 - 0.004 16.6 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lipocalin_3 PF12702.2 GAO87444.1 - 0.028 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like 2-Hacid_dh_C PF02826.14 GAO87444.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAO87444.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc97_Spc98 PF04130.8 GAO87445.1 - 6.3e-67 226.1 0.0 9.5e-63 212.3 0.0 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family ThiF PF00899.16 GAO87446.1 - 1.9e-53 179.9 0.0 1.4e-30 105.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 GAO87446.1 - 2.8e-42 142.1 1.2 2.5e-26 91.0 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 GAO87446.1 - 9.6e-39 132.3 0.0 2.4e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 GAO87446.1 - 2.9e-25 87.3 2.2 1.1e-21 75.8 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 GAO87446.1 - 5.5e-23 80.7 0.0 1.4e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO87446.1 - 8.8e-16 57.5 0.0 3.6e-15 55.5 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO87446.1 - 4.2e-06 27.1 0.0 0.00032 21.1 0.0 3.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO87446.1 - 5.2e-06 26.3 0.0 1.9e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO87446.1 - 0.00086 19.4 0.1 0.018 15.2 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 GAO87447.1 - 1.2e-67 223.6 3.8 3.6e-23 81.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAO87447.1 - 5.4e-26 90.5 1.7 5.8e-13 48.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAO87447.1 - 5e-22 75.4 2.9 1e-06 27.6 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 GAO87447.1 - 8.1e-18 62.8 3.0 1.4e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAO87447.1 - 3.6e-16 57.5 4.1 0.00032 20.3 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAO87447.1 - 6.4e-14 51.3 0.8 4.1e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAO87447.1 - 4.3e-08 33.1 0.1 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAO87447.1 - 0.0029 17.3 4.8 4.2 7.1 0.1 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 GAO87447.1 - 0.0066 16.0 0.1 5.1 6.8 0.0 3.2 3 0 0 3 3 3 1 EF hand IBP39 PF11422.3 GAO87447.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Initiator binding protein 39 kDa DUF4452 PF14618.1 GAO87449.1 - 2.9e-74 248.3 9.3 4.3e-74 247.8 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.14 GAO87451.1 - 2e-14 53.0 2.1 2e-14 53.0 1.5 2.9 2 1 1 3 3 3 1 SNARE domain Phage_GP20 PF06810.6 GAO87451.1 - 0.0017 17.8 2.3 0.69 9.3 0.4 2.4 2 0 0 2 2 2 2 Phage minor structural protein GP20 IncA PF04156.9 GAO87451.1 - 0.014 15.0 3.6 0.014 15.0 2.5 2.9 3 0 0 3 3 2 0 IncA protein EzrA PF06160.7 GAO87451.1 - 0.028 12.6 0.1 0.028 12.6 0.0 2.3 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF1664 PF07889.7 GAO87451.1 - 0.029 14.1 2.9 0.15 11.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 GAO87451.1 - 0.044 12.8 1.6 1.5 7.8 0.0 2.4 2 1 0 2 2 2 0 Tropomyosin DUF3051 PF11252.3 GAO87451.1 - 0.063 12.7 0.3 0.12 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3051) HrpB7 PF09486.5 GAO87451.1 - 0.084 12.8 1.4 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.11 GAO87451.1 - 0.17 11.9 4.5 1.1 9.3 0.3 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein Cep57_MT_bd PF06657.8 GAO87451.1 - 0.23 11.4 4.3 0.52 10.3 1.5 2.5 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PilJ PF13675.1 GAO87451.1 - 0.4 11.0 6.8 0.31 11.3 0.7 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin PF00804.20 GAO87451.1 - 0.42 10.7 4.8 0.13 12.4 0.3 2.2 2 1 0 2 2 2 0 Syntaxin SlyX PF04102.7 GAO87451.1 - 0.67 10.3 6.7 2 8.8 0.4 3.4 2 2 2 4 4 4 0 SlyX Lebercilin PF15619.1 GAO87451.1 - 0.85 8.9 5.6 0.18 11.1 0.3 2.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Use1 PF09753.4 GAO87451.1 - 0.97 8.8 4.3 5.8 6.2 3.0 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 FlxA PF14282.1 GAO87451.1 - 1.1 9.2 5.6 0.25 11.3 0.6 2.1 2 0 0 2 2 2 0 FlxA-like protein Synaptobrevin PF00957.16 GAO87451.1 - 1.2 8.7 4.6 0.77 9.4 1.3 2.1 2 0 0 2 2 2 0 Synaptobrevin Med9 PF07544.8 GAO87451.1 - 3.1 7.6 5.5 5.4 6.8 0.2 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-TRAF PF02176.13 GAO87452.1 - 1.5e-14 54.0 25.7 8.9e-10 38.8 3.6 4.7 2 1 3 5 5 5 4 TRAF-type zinc finger zf-RING_2 PF13639.1 GAO87452.1 - 5e-08 32.6 12.1 5e-08 32.6 8.4 3.4 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 GAO87452.1 - 3.4e-06 26.6 11.4 3.4e-06 26.6 7.9 3.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO87452.1 - 5.8e-06 25.8 10.8 5.8e-06 25.8 7.5 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO87452.1 - 6.3e-06 25.7 9.4 6.3e-06 25.7 6.5 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO87452.1 - 1.6e-05 24.7 11.6 1.6e-05 24.7 8.1 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO87452.1 - 2.9e-05 23.6 5.6 2.9e-05 23.6 3.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAO87452.1 - 3.2e-05 23.7 11.1 3.2e-05 23.7 7.7 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Sina PF03145.11 GAO87452.1 - 0.14 11.8 17.2 1.8 8.1 0.4 3.1 1 1 2 3 3 3 0 Seven in absentia protein family Het-C PF07217.6 GAO87453.1 - 1.3e-301 1001.1 0.0 1.7e-301 1000.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PhyH PF05721.8 GAO87454.1 - 4.6e-09 36.6 0.1 1.5e-08 34.9 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_23 PF13489.1 GAO87455.1 - 7.7e-22 77.7 0.0 7.2e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87455.1 - 7e-10 39.2 0.0 3.5e-08 33.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87455.1 - 1.1e-09 38.8 0.0 1.2e-08 35.5 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87455.1 - 8.3e-09 35.8 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87455.1 - 3.6e-08 33.1 0.0 2.4e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87455.1 - 2.3e-05 24.3 0.0 0.00013 21.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO87455.1 - 0.0051 15.9 0.0 0.36 9.8 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 GAO87455.1 - 0.0091 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAO87455.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAO87455.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 GAO87455.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 GAO87455.1 - 0.025 14.5 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 GAO87455.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 GAO87455.1 - 0.12 11.3 0.0 0.3 10.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase IBN_N PF03810.14 GAO87456.1 - 7.1e-10 38.6 1.0 5.3e-08 32.6 0.1 3.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAO87456.1 - 0.0016 18.3 1.3 0.095 12.6 0.0 4.0 4 2 0 4 4 4 1 Exportin 1-like protein Proteasom_PSMB PF10508.4 GAO87456.1 - 0.0028 15.9 0.3 0.039 12.2 0.0 2.8 2 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit HORMA PF02301.13 GAO87457.1 - 4.2e-27 94.9 0.0 5.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBR PF01485.16 GAO87458.1 - 0.00011 21.9 11.5 0.00011 21.9 8.0 3.7 3 1 0 3 3 3 2 IBR domain CUE PF02845.11 GAO87458.1 - 0.00012 21.4 0.0 0.44 10.0 0.0 2.8 3 0 0 3 3 3 2 CUE domain Acetyltransf_7 PF13508.1 GAO87459.1 - 5.3e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO87459.1 - 5.9e-07 29.4 0.1 1.8e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO87459.1 - 5.6e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO87459.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO87459.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF2036 PF09724.4 GAO87460.1 - 5.6e-19 68.4 0.0 8.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) SH3_4 PF06347.8 GAO87460.1 - 0.00083 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Anp1 PF03452.9 GAO87461.1 - 2.2e-122 407.4 0.0 3.1e-122 406.9 0.0 1.2 1 0 0 1 1 1 1 Anp1 GlcNAc PF11397.3 GAO87461.1 - 0.036 13.1 0.1 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) SPT16 PF08644.6 GAO87461.1 - 0.24 11.2 1.8 0.4 10.5 0.5 1.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) adh_short PF00106.20 GAO87462.1 - 4e-12 46.3 0.0 5.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO87462.1 - 7.4e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAO87462.1 - 0.082 11.8 0.3 0.22 10.3 0.2 1.7 1 1 1 2 2 2 0 Male sterility protein ADH_zinc_N PF00107.21 GAO87463.1 - 1.5e-27 95.6 0.7 2.5e-27 94.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO87463.1 - 3.2e-10 39.7 0.3 7.6e-10 38.5 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 GAO87463.1 - 2.2e-05 23.9 0.2 6.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.14 GAO87463.1 - 0.00016 20.8 0.5 0.00019 20.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAO87463.1 - 0.0024 18.2 0.8 0.026 14.9 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAO87463.1 - 0.0036 17.4 0.1 0.0059 16.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 GAO87463.1 - 0.0039 17.2 0.2 0.0053 16.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAO87463.1 - 0.0057 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAO87463.1 - 0.0075 16.5 1.2 0.032 14.4 0.8 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding CPSase_L_chain PF00289.17 GAO87463.1 - 0.0079 16.2 0.1 0.015 15.4 0.1 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_2 PF00890.19 GAO87463.1 - 0.013 14.3 2.3 0.042 12.7 1.0 1.9 1 1 1 2 2 2 0 FAD binding domain Hydrolase_6 PF13344.1 GAO87463.1 - 0.021 14.7 0.0 2.1 8.2 0.0 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase TrkA_N PF02254.13 GAO87463.1 - 0.024 14.6 0.2 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.20 GAO87463.1 - 0.051 12.8 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DAO PF01266.19 GAO87463.1 - 0.15 10.9 3.1 0.12 11.2 0.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO87463.1 - 0.21 11.4 1.3 0.38 10.6 0.9 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA_bind PF01588.15 GAO87464.1 - 1.5e-22 79.1 0.0 2.1e-20 72.3 0.0 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 GAO87464.1 - 2.8e-10 40.5 0.0 9e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO87464.1 - 6.3e-06 25.9 0.0 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO87464.1 - 0.0018 18.2 0.1 0.0089 16.0 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 GAO87464.1 - 0.23 9.9 1.3 0.34 9.3 0.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp PF00026.18 GAO87465.1 - 1.1e-65 221.9 8.8 1.4e-65 221.6 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAO87465.1 - 1.5e-05 25.3 2.8 0.22 12.0 0.5 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 GAO87465.1 - 0.00012 22.1 0.0 0.0015 18.4 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAO87465.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal ParA PF10609.4 GAO87466.1 - 1.2e-34 118.0 0.0 2.4e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAO87466.1 - 1.7e-16 60.1 0.0 2.6e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 GAO87466.1 - 3.9e-06 26.1 1.3 0.00014 21.0 0.2 2.7 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 GAO87466.1 - 4.2e-06 26.7 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 GAO87466.1 - 0.0023 17.5 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 GAO87466.1 - 0.0032 16.5 0.0 0.007 15.4 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_30 PF13604.1 GAO87466.1 - 0.0041 16.7 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAO87466.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO87466.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 GAO87466.1 - 0.057 12.5 0.0 1 8.4 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 GAO87466.1 - 0.082 12.6 0.0 0.88 9.3 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 GAO87466.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 GAO87466.1 - 0.15 12.9 0.1 0.25 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO87466.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ChW PF07538.6 GAO87466.1 - 3 7.4 5.3 0.5 9.9 0.4 2.1 2 0 0 2 2 2 0 Clostridial hydrophobic W PEMT PF04191.8 GAO87467.1 - 2.8e-58 194.5 11.6 3.3e-36 123.6 0.4 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 GAO87468.1 - 1.4e-32 112.8 0.0 2.3e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ProRS-C_1 PF09180.6 GAO87471.1 - 2e-22 78.8 1.0 5.4e-22 77.4 0.7 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 GAO87471.1 - 2.1e-22 79.5 0.1 3.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAO87471.1 - 9.6e-11 41.4 0.0 5e-10 39.1 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain NARP1 PF12569.3 GAO87471.1 - 6.4 5.4 10.4 9.9 4.7 7.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cpn60_TCP1 PF00118.19 GAO87472.1 - 1.2e-143 479.2 13.1 1.4e-143 479.0 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 GAO87473.1 - 2.2e-22 78.0 2.8 3.9e-06 26.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Borealin PF10512.4 GAO87473.1 - 0.032 14.1 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 S1 PF00575.18 GAO87474.1 - 3.7e-82 270.4 29.3 6.3e-17 61.4 0.9 12.1 12 0 0 12 12 12 11 S1 RNA binding domain TPR_16 PF13432.1 GAO87474.1 - 8.5e-08 32.6 0.1 0.23 12.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO87474.1 - 3.1e-07 30.6 0.0 0.12 12.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAO87474.1 - 6.9e-06 26.2 0.5 1.9 9.3 0.1 5.1 2 1 3 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 GAO87474.1 - 0.00046 20.0 15.9 0.0012 18.6 0.1 4.5 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_7 PF13176.1 GAO87474.1 - 0.013 15.2 1.0 0.6 10.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAO87474.1 - 0.013 15.3 1.5 9.9 6.1 0.1 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 GAO87474.1 - 0.014 15.3 0.0 6.1 7.0 0.0 3.1 2 0 0 2 2 2 0 PPR repeat TPR_15 PF13429.1 GAO87474.1 - 0.022 13.8 0.9 0.058 12.4 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO87474.1 - 0.53 10.3 4.1 6.5 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2052 PF09747.4 GAO87475.1 - 3.8 7.3 16.5 0.36 10.7 3.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UreD PF01774.12 GAO87477.1 - 6e-63 212.0 0.0 7.2e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 GAO87478.1 - 1.4e-37 127.9 0.2 5e-37 126.1 0.2 2.0 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 GAO87478.1 - 2.8e-06 27.5 0.3 0.23 11.7 0.2 4.1 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.17 GAO87478.1 - 0.005 16.8 0.1 1.2e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.18 GAO87479.1 - 7.3e-95 307.9 10.8 3.6e-14 51.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAO87479.1 - 2e-24 85.6 0.1 4.4e-10 39.7 0.0 5.7 1 1 5 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 GAO87479.1 - 1.1e-21 76.6 8.0 4.3e-10 39.7 0.1 6.1 5 1 2 7 7 7 3 HEAT-like repeat IBB PF01749.15 GAO87479.1 - 3.3e-21 75.2 3.7 6e-21 74.4 2.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 GAO87479.1 - 1.2e-20 71.6 0.4 1.1e-06 28.1 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 GAO87479.1 - 3e-12 46.2 0.0 0.00051 19.2 0.0 4.5 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 GAO87479.1 - 3.3e-06 25.7 0.0 0.00069 18.0 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 GAO87479.1 - 0.00012 21.9 0.0 1.4 8.8 0.0 4.5 3 2 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 GAO87479.1 - 0.0035 15.6 0.0 0.85 7.8 0.0 3.0 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 GAO87479.1 - 0.0064 16.8 5.0 0.59 10.7 0.0 4.7 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 GAO87479.1 - 0.021 14.3 0.0 36 4.0 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 GAO87479.1 - 0.21 10.6 0.0 0.4 9.6 0.0 1.6 1 0 0 1 1 1 0 Mo25-like POT1 PF02765.12 GAO87480.1 - 3.2e-21 75.7 0.0 2.8e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 GAO87480.1 - 0.016 15.0 0.0 0.42 10.5 0.0 3.0 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain Turandot PF07240.6 GAO87481.1 - 0.035 13.6 0.7 0.88 9.1 0.0 2.8 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot DUF733 PF05306.6 GAO87481.1 - 0.078 13.2 4.8 0.19 12.0 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Peptidase_M13_N PF05649.8 GAO87481.1 - 0.11 11.5 0.5 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Peptidase family M13 TRAP_alpha PF03896.11 GAO87482.1 - 2e-12 46.6 0.2 3.3e-12 45.9 0.1 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DcpS_C PF11969.3 GAO87483.1 - 8.2e-17 61.4 3.7 4.5e-16 59.1 2.6 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAO87483.1 - 8.3e-16 58.3 0.8 2.2e-15 56.9 0.6 1.7 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 GAO87484.1 - 2.7e-18 65.8 0.9 1.4e-17 63.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAO87484.1 - 1.6e-17 63.3 0.0 3.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAO87484.1 - 6.9e-13 48.2 0.0 1.9e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 GAO87484.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 GAO87484.1 - 9.2e-09 35.0 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 GAO87484.1 - 4e-05 22.6 0.6 0.00037 19.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DND1_DSRM PF14709.1 GAO87484.1 - 0.0031 17.7 0.6 0.009 16.2 0.4 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.1 GAO87484.1 - 0.0034 17.5 0.3 0.015 15.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAO87484.1 - 0.0067 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PhoH PF02562.11 GAO87484.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 GAO87484.1 - 0.017 14.2 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 GAO87484.1 - 0.052 13.0 0.2 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zot PF05707.7 GAO87484.1 - 0.067 12.6 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Podovirus_Gp16 PF05894.7 GAO87484.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Podovirus DNA encapsidation protein (Gp16) AAA_23 PF13476.1 GAO87484.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain Cyclin_N PF00134.18 GAO87485.1 - 8.1e-44 148.2 0.2 1.4e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAO87485.1 - 2.5e-31 108.0 0.0 7.1e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 GAO87486.1 - 0.00076 19.3 11.3 0.0014 18.4 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.9 GAO87487.1 - 2.8e-35 121.1 0.0 2.8e-35 121.1 0.0 3.7 3 1 1 4 4 4 1 RNA polymerase III RPC4 DUF2477 PF10631.4 GAO87487.1 - 0.34 11.1 4.5 0.94 9.6 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Med3 PF11593.3 GAO87487.1 - 3.9 6.6 13.0 0.26 10.4 5.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1180 PF06679.7 GAO87488.1 - 0.044 13.6 0.3 0.056 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF485 PF04341.7 GAO87489.1 - 0.0086 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF485 Neur_chan_memb PF02932.11 GAO87489.1 - 0.018 14.9 0.0 0.018 14.9 0.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.16 GAO87489.1 - 0.059 12.5 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4059 PF13268.1 GAO87489.1 - 0.1 12.8 0.1 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) UPRTase PF14681.1 GAO87490.1 - 1.2e-72 243.4 0.0 1.4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAO87490.1 - 9.7e-06 25.3 0.0 2.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 GAO87491.1 - 5.4e-31 106.9 25.4 5.5e-21 74.6 4.7 3.8 2 1 1 3 3 3 2 CrcB-like protein Fungal_trans PF04082.13 GAO87492.1 - 6.1e-20 71.1 3.6 9.5e-20 70.5 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 GAO87492.1 - 1.5e-07 31.3 14.9 0.0001 22.3 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO87492.1 - 0.0001 22.4 14.6 0.0041 17.3 3.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO87492.1 - 0.00043 20.4 16.2 0.035 14.4 4.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAO87492.1 - 0.58 10.1 4.2 15 5.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger RasGEF PF00617.14 GAO87493.1 - 4.9e-63 212.2 0.0 1e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAO87493.1 - 8.7e-29 99.6 0.7 1.8e-28 98.6 0.2 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 GAO87493.1 - 7.2e-16 57.3 0.1 1.4e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO87493.1 - 1.7e-14 53.1 0.1 4.3e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO87493.1 - 1.7e-10 40.2 0.0 4e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 GAO87493.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 WW domain DegS PF05384.6 GAO87493.1 - 0.08 12.1 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Sensor protein DegS JAB PF01398.16 GAO87494.1 - 9.4e-27 93.0 0.0 1.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAO87494.1 - 3.1e-06 26.6 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 GAO87495.1 - 2.7e-77 260.8 4.2 1.2e-76 258.7 2.3 1.9 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 GAO87495.1 - 0.11 12.3 2.3 0.24 11.2 0.7 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 GAO87495.1 - 5.9 6.6 6.9 3.1 7.5 0.7 3.0 4 0 0 4 4 4 0 LXG domain of WXG superfamily tRNA-synt_1c PF00749.16 GAO87496.1 - 5.7e-95 317.5 0.0 7.1e-95 317.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 GAO87497.1 - 9.8e-25 86.2 0.3 1.6e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 GAO87497.1 - 9.1e-22 76.5 3.6 1.6e-21 75.7 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAO87497.1 - 4.4e-14 52.2 16.8 7.4e-14 51.5 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAO87497.1 - 0.27 10.9 11.3 0.34 10.6 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 GAO87497.1 - 0.82 9.7 11.3 1.7 8.7 1.2 2.3 1 1 1 2 2 2 0 Stc1 domain zf-CHY PF05495.7 GAO87497.1 - 1.2 9.3 5.9 3.2 7.9 0.4 2.4 2 0 0 2 2 2 0 CHY zinc finger DUF1356 PF07092.7 GAO87497.1 - 5.5 6.0 6.9 7.3 5.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) ILVD_EDD PF00920.16 GAO87498.1 - 9.6e-150 499.4 0.0 1.1e-149 499.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family SHOCT PF09851.4 GAO87498.1 - 1.6 8.3 6.7 0.088 12.3 0.4 2.2 2 0 0 2 2 2 0 Short C-terminal domain Fungal_trans PF04082.13 GAO87499.1 - 2.5e-19 69.1 0.0 3.9e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO87500.1 - 5.1e-41 140.5 42.0 5.1e-41 140.5 29.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87500.1 - 2.4e-08 32.9 18.6 2.4e-08 32.9 12.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter HAD_2 PF13419.1 GAO87501.1 - 9.5e-28 97.5 0.0 2.3e-27 96.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 GAO87501.1 - 4.1e-05 22.6 0.0 0.00069 18.6 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.1 GAO87501.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acetyltransf_1 PF00583.19 GAO87502.1 - 1.6e-05 24.8 0.1 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.1 GAO87502.1 - 0.0004 20.3 0.2 0.0013 18.7 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO87502.1 - 0.0011 19.0 0.1 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hexokinase_1 PF00349.16 GAO87503.1 - 1.1e-53 181.6 0.0 1.9e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 GAO87503.1 - 1.1e-51 175.4 0.0 2.5e-39 134.9 0.0 2.1 1 1 1 2 2 2 2 Hexokinase WHH PF14414.1 GAO87504.1 - 5 6.4 6.2 2.2 7.5 0.2 2.8 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 4HBT PF03061.17 GAO87505.1 - 3.2e-10 39.9 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PseudoU_synth_2 PF00849.17 GAO87506.1 - 2.1e-26 92.7 0.0 3.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2863 PF11062.3 GAO87506.1 - 0.029 12.4 0.1 0.054 11.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2863) GFA PF04828.9 GAO87506.1 - 0.074 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme S4 PF01479.20 GAO87506.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 S4 domain Ribosomal_L32e PF01655.13 GAO87507.1 - 6.9e-48 161.2 1.0 1.3e-47 160.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 GAO87507.1 - 1.5e-14 54.4 0.0 5.4e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO87507.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.6 GAO87508.1 - 6.2e-10 38.8 20.2 2.3e-09 37.0 9.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Laminin_II PF06009.7 GAO87508.1 - 0.012 15.3 9.6 0.66 9.7 2.6 2.2 2 0 0 2 2 2 0 Laminin Domain II Nup54 PF13874.1 GAO87508.1 - 0.021 14.4 1.4 0.021 14.4 1.0 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2894 PF11445.3 GAO87508.1 - 0.041 14.1 20.6 36 4.5 14.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) HSBP1 PF06825.7 GAO87508.1 - 0.044 13.3 2.1 0.21 11.1 0.6 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 TBPIP PF07106.8 GAO87508.1 - 0.061 12.8 9.7 0.58 9.6 0.1 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 GAO87508.1 - 0.061 13.2 1.1 0.061 13.2 0.8 3.2 2 1 1 3 3 3 0 bZIP transcription factor Lsr2 PF11774.3 GAO87508.1 - 0.07 13.0 0.3 0.07 13.0 0.2 2.3 2 1 1 3 3 3 0 Lsr2 ECH PF00378.15 GAO87508.1 - 0.071 12.2 0.2 0.071 12.2 0.1 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Spc7 PF08317.6 GAO87508.1 - 0.094 11.3 9.3 1.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CpXC PF14353.1 GAO87508.1 - 0.11 12.4 1.3 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 CpXC protein GFA PF04828.9 GAO87508.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 GAO87508.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S27a UPF0184 PF03670.8 GAO87508.1 - 0.14 12.3 5.0 1.1 9.4 0.7 2.9 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0184) Jnk-SapK_ap_N PF09744.4 GAO87508.1 - 0.18 11.8 17.0 0.23 11.4 7.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LOH1CR12 PF10158.4 GAO87508.1 - 0.29 10.9 3.5 1.9 8.3 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein I_LWEQ PF01608.12 GAO87508.1 - 0.39 10.6 14.1 2.5 8.0 5.2 2.2 2 0 0 2 2 2 0 I/LWEQ domain AATF-Che1 PF13339.1 GAO87508.1 - 0.4 10.8 14.3 0.52 10.4 4.9 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor IFT57 PF10498.4 GAO87508.1 - 0.47 9.1 8.8 0.2 10.3 2.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Macoilin PF09726.4 GAO87508.1 - 0.65 8.2 15.3 0.97 7.6 10.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Laminin_I PF06008.9 GAO87508.1 - 0.68 9.1 18.7 0.6 9.3 0.6 2.5 2 1 0 2 2 2 0 Laminin Domain I RE_Alw26IDE PF09665.5 GAO87508.1 - 0.69 8.5 3.6 11 4.5 0.0 2.0 2 0 0 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) AF0941-like PF14591.1 GAO87508.1 - 0.81 9.7 6.0 1 9.4 0.0 2.4 2 1 0 2 2 2 0 AF0941-like DUF948 PF06103.6 GAO87508.1 - 0.87 9.4 3.4 6.4 6.7 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MtrG PF04210.8 GAO87508.1 - 0.91 9.2 3.3 9.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G NPV_P10 PF05531.7 GAO87508.1 - 0.96 9.7 4.8 1.7 8.9 0.2 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TFIIA PF03153.8 GAO87508.1 - 1 9.1 15.0 1.2 8.9 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_tail_1 PF01576.14 GAO87508.1 - 1.1 6.8 24.8 3.4 5.2 0.2 2.4 2 1 0 2 2 2 0 Myosin tail Lebercilin PF15619.1 GAO87508.1 - 1.4 8.2 20.7 2.9 7.2 9.4 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Hormone_1 PF00103.15 GAO87508.1 - 1.4 8.1 5.6 14 4.9 0.4 2.4 2 1 0 2 2 2 0 Somatotropin hormone family DUF972 PF06156.8 GAO87508.1 - 1.7 9.0 12.3 1.3 9.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 GAO87508.1 - 1.7 9.0 15.1 0.35 11.2 0.3 3.6 2 1 2 4 4 4 0 SlyX IncA PF04156.9 GAO87508.1 - 2.4 7.7 25.4 3.4 7.1 11.1 2.2 1 1 1 2 2 2 0 IncA protein ECM11 PF15463.1 GAO87508.1 - 2.8 8.2 18.1 14 5.9 10.8 2.4 1 1 1 2 2 2 0 Extracellular mutant protein 11 Striatin PF08232.7 GAO87508.1 - 2.8 8.2 20.9 10 6.4 8.7 2.8 1 1 1 2 2 2 0 Striatin family SPX PF03105.14 GAO87508.1 - 3.4 7.3 14.3 31 4.2 9.9 2.1 1 1 0 1 1 1 0 SPX domain AAA_13 PF13166.1 GAO87508.1 - 3.5 5.9 13.4 0.81 8.0 0.3 2.1 1 1 0 2 2 2 0 AAA domain YlqD PF11068.3 GAO87508.1 - 3.7 7.5 15.2 3.6 7.6 5.3 2.4 2 0 0 2 2 2 0 YlqD protein ECSIT PF06239.6 GAO87508.1 - 4 6.2 7.1 0.77 8.5 2.1 1.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Vac_Fusion PF02346.11 GAO87508.1 - 6.8 6.1 7.4 2.3 7.7 2.3 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein RRM_1 PF00076.17 GAO87509.1 - 8.2e-17 60.6 0.0 1.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO87509.1 - 1.3e-14 53.8 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO87509.1 - 5.4e-06 26.1 0.0 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27 PF10344.4 GAO87510.1 - 7.3e-255 847.8 0.0 2.9e-254 845.8 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 GAO87510.1 - 1.7e-176 587.6 0.2 1.7e-176 587.6 0.1 2.6 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 GAO87510.1 - 1.7e-159 531.2 10.2 1.7e-159 531.2 7.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 GAO87510.1 - 3.5e-59 199.0 0.4 7.6e-59 197.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 GAO87510.1 - 2.8e-51 173.5 0.2 1.6e-50 171.0 0.0 2.4 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 GAO87510.1 - 7.5e-34 116.2 0.0 6.7e-33 113.2 0.0 2.8 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.7 GAO87512.1 - 1.8e-22 78.9 0.2 4.2e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 GAO87512.1 - 0.0071 15.9 0.3 0.14 11.8 0.0 3.1 3 0 0 3 3 3 1 MarR family MarR PF01047.17 GAO87512.1 - 0.012 15.2 0.0 0.46 10.2 0.0 3.4 4 0 0 4 4 4 0 MarR family HTH_36 PF13730.1 GAO87512.1 - 0.077 13.1 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain UQ_con PF00179.21 GAO87513.1 - 3.1e-21 75.2 0.0 4.8e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAO87513.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-DHHC PF01529.15 GAO87514.1 - 2.2e-21 76.0 3.7 2.2e-21 76.0 2.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.17 GAO87515.1 - 1e-31 109.9 11.8 1e-31 109.9 8.2 1.9 2 0 0 2 2 2 1 Rhomboid family DUF3317 PF11779.3 GAO87516.1 - 4.1e-20 70.9 2.0 4.1e-20 70.9 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3317) PgaD PF13994.1 GAO87516.1 - 0.037 13.5 0.3 0.052 13.0 0.2 1.2 1 0 0 1 1 1 0 PgaD-like protein Kinetochor_Ybp2 PF08568.5 GAO87517.1 - 3e-181 603.8 0.0 3.6e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.1 GAO87518.1 - 2.5e-14 53.0 0.0 2e-06 27.5 0.0 3.7 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 GAO87518.1 - 2.2e-12 46.3 1.4 5.5e-05 22.8 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF4175 PF13779.1 GAO87518.1 - 0.066 10.9 9.8 0.12 9.9 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cyanate_lyase PF02560.9 GAO87519.1 - 1.3e-28 98.2 0.0 1.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 GAO87519.1 - 0.015 15.1 0.1 0.029 14.2 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.1 GAO87519.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 GAO87519.1 - 0.095 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain zf-C2H2_4 PF13894.1 GAO87520.1 - 8.1e-11 41.4 15.5 0.51 10.7 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO87520.1 - 1e-10 41.4 14.7 0.17 12.0 0.1 6.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAO87520.1 - 2.9e-09 36.7 20.7 0.041 14.2 0.2 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 GAO87520.1 - 4e-05 23.6 8.3 6 7.2 0.0 6.2 6 0 0 6 6 6 1 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.9 GAO87520.1 - 4.3e-05 22.8 3.8 0.1 12.0 0.1 4.0 3 1 1 4 4 4 2 Rad50 zinc hook motif GAGA PF09237.6 GAO87520.1 - 0.00063 19.2 0.3 0.38 10.3 0.0 3.4 3 0 0 3 3 3 1 GAGA factor zf-C2H2_2 PF12756.2 GAO87520.1 - 0.15 12.1 21.7 8.5 6.5 0.1 4.4 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.4 GAO87520.1 - 0.28 10.6 7.9 0.26 10.6 0.1 3.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn-ribbon_8 PF09723.5 GAO87520.1 - 0.54 10.2 15.3 0.27 11.1 1.4 4.3 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 GAO87520.1 - 0.64 10.0 18.7 8.2 6.4 0.0 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Trm112p PF03966.11 GAO87520.1 - 1.4 9.3 4.8 48 4.4 1.2 3.5 3 1 0 3 3 3 0 Trm112p-like protein zf-Di19 PF05605.7 GAO87520.1 - 1.8 8.7 16.8 3.9 7.6 1.5 4.3 3 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF3795 PF12675.2 GAO87520.1 - 2 8.6 15.4 1.8 8.8 3.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) Carb_kinase PF01256.12 GAO87521.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase DUF4106 PF13388.1 GAO87521.1 - 0.61 8.9 2.6 0.68 8.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) GluR_Homer-bdg PF10606.4 GAO87523.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor DNA_pol_B PF00136.16 GAO87525.1 - 3.9e-146 487.5 3.4 6.1e-146 486.8 2.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAO87525.1 - 2.9e-85 286.0 0.0 7e-85 284.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAO87525.1 - 1e-22 79.9 4.7 2.2e-22 78.8 3.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 GAO87525.1 - 0.0039 17.0 0.3 0.017 14.9 0.2 2.2 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 GAO87525.1 - 0.19 11.4 9.6 0.041 13.6 0.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAO PF01266.19 GAO87526.1 - 1.6e-54 185.2 0.0 1.8e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO87526.1 - 2.4e-06 27.5 0.2 0.00033 20.6 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87526.1 - 6.3e-05 22.9 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 GAO87526.1 - 0.00011 22.1 0.1 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.1 GAO87526.1 - 0.00016 21.8 0.1 0.0038 17.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO87526.1 - 0.0033 17.1 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding ApbA PF02558.11 GAO87526.1 - 0.006 16.0 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAO87526.1 - 0.0086 14.9 0.3 0.025 13.4 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAO87526.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAO87526.1 - 0.031 14.6 0.2 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAO87526.1 - 0.045 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 GAO87526.1 - 0.045 12.7 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.20 GAO87527.1 - 2.8e-37 128.2 0.0 1.4e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87527.1 - 2.6e-17 62.7 0.0 9.1e-16 57.6 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.19 GAO87528.1 - 4.2e-30 104.8 0.3 5.9e-30 104.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO87528.1 - 6.3e-25 87.9 0.0 1.6e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAO87528.1 - 5.3e-23 80.2 0.7 8.9e-23 79.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO87528.1 - 0.00014 22.1 0.7 0.00039 20.6 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3716 PF12511.3 GAO87529.1 - 2.9e-15 55.6 3.9 4.7e-15 54.9 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Syja_N PF02383.13 GAO87530.1 - 3.7e-95 318.3 0.0 6.6e-95 317.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 GAO87531.1 - 3.6e-102 341.1 1.9 6.3e-102 340.3 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 GAO87531.1 - 6e-22 78.1 0.4 2.1e-21 76.4 0.3 2.0 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAO87531.1 - 1.1e-05 24.9 0.0 3.2e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAPPC-Trs85 PF12739.2 GAO87532.1 - 2.5e-121 405.1 0.0 4.2e-121 404.4 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 GAO87533.1 - 9.4e-18 64.1 22.0 4.6e-17 61.9 15.1 2.1 1 1 1 2 2 2 1 Snf7 AAA_23 PF13476.1 GAO87533.1 - 2.5 8.3 15.2 2.5 8.4 1.0 2.3 2 0 0 2 2 2 0 AAA domain SAP PF02037.22 GAO87534.1 - 5.6e-06 25.7 0.0 1.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 GAO87534.1 - 0.00076 19.3 2.3 0.0031 17.3 0.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PRP21_like_P PF12230.3 GAO87534.1 - 0.0012 18.3 0.6 0.004 16.6 0.0 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf-C3HC4_2 PF13923.1 GAO87534.1 - 0.0039 17.1 6.4 0.015 15.2 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.1 GAO87534.1 - 0.015 14.9 0.2 0.034 13.8 0.1 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-RING_5 PF14634.1 GAO87534.1 - 0.02 14.6 2.7 0.094 12.4 0.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO87534.1 - 0.048 13.3 4.9 0.054 13.1 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO87534.1 - 0.058 13.1 4.6 0.067 12.9 0.2 2.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.1 GAO87534.1 - 0.074 12.8 4.7 0.25 11.2 0.5 2.3 2 0 0 2 2 2 0 Ring finger domain Rad50_zn_hook PF04423.9 GAO87534.1 - 0.079 12.4 0.8 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.6 GAO87534.1 - 0.083 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-Nse PF11789.3 GAO87534.1 - 0.11 12.0 1.0 0.4 10.2 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 GAO87534.1 - 0.39 10.4 3.7 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDC27 PF09507.5 GAO87535.1 - 2.6e-118 396.0 25.4 3e-118 395.7 17.6 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 GAO87536.1 - 3.3e-182 605.8 0.0 3.8e-182 605.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Pex2_Pex12 PF04757.9 GAO87537.1 - 1.9e-59 200.8 6.1 2.4e-59 200.5 4.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 GAO87537.1 - 3.8e-07 29.8 3.0 6.7e-07 29.0 2.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAO87537.1 - 1.8e-06 27.8 5.0 2e-06 27.7 2.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO87537.1 - 9.5e-05 22.1 1.5 0.00014 21.6 0.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAO87537.1 - 0.0017 17.9 3.3 0.0029 17.2 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO87537.1 - 0.022 14.4 1.5 0.039 13.6 1.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Oligomerisation PF02410.10 GAO87538.1 - 6.4e-06 26.1 0.0 0.0014 18.5 0.0 3.2 2 1 0 2 2 2 2 Oligomerisation domain NMD3 PF04981.8 GAO87539.1 - 1.5e-77 259.9 2.6 1.5e-77 259.9 1.8 1.7 2 0 0 2 2 2 1 NMD3 family DUF35_N PF12172.3 GAO87539.1 - 0.0099 15.7 0.1 5.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) LETM1 PF07766.8 GAO87539.1 - 0.11 11.4 3.6 0.24 10.3 2.5 1.4 1 0 0 1 1 1 0 LETM1-like protein FYVE PF01363.16 GAO87539.1 - 3.1 7.7 6.0 11 6.0 1.7 2.4 2 0 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 GAO87539.1 - 5.8 6.7 7.2 0.68 9.7 0.6 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.17 GAO87540.1 - 0.011 15.3 0.0 0.15 11.7 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO87540.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc1_Nup PF09531.5 GAO87540.1 - 2.1 6.6 6.9 3 6.1 4.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mito_carr PF00153.22 GAO87541.1 - 4e-64 212.3 1.2 1.6e-21 75.7 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3357 PF11837.3 GAO87541.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Ammonium_transp PF00909.16 GAO87541.1 - 0.069 11.6 0.0 7.2 4.9 0.0 2.3 2 0 0 2 2 2 0 Ammonium Transporter Family WAC_Acf1_DNA_bd PF10537.4 GAO87542.1 - 5.7e-31 106.7 0.0 2.9e-30 104.4 0.0 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 GAO87542.1 - 4.3e-18 64.8 3.2 8.2e-18 63.9 2.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 GAO87542.1 - 4.2e-09 35.9 0.4 9.2e-09 34.8 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 GAO87542.1 - 0.00012 21.8 2.6 0.00038 20.2 0.1 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 GAO87542.1 - 0.00062 19.4 0.4 0.0016 18.2 0.3 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF4094 PF13334.1 GAO87542.1 - 0.81 10.1 6.2 0.36 11.2 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Myb_Cef PF11831.3 GAO87543.1 - 0.03 13.5 1.7 0.039 13.1 1.2 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component Alg6_Alg8 PF03155.10 GAO87544.1 - 5.2e-122 408.0 29.3 6.5e-122 407.7 20.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 GAO87545.1 - 3.6e-30 104.8 0.0 4.8e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family TBPIP PF07106.8 GAO87545.1 - 0.0018 17.8 2.0 0.0029 17.1 1.4 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Zw10 PF06248.8 GAO87545.1 - 0.0024 16.1 2.6 0.0032 15.6 1.8 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 FadA PF09403.5 GAO87545.1 - 0.016 15.1 0.5 0.029 14.4 0.3 1.3 1 0 0 1 1 1 0 Adhesion protein FadA EMP24_GP25L PF01105.19 GAO87545.1 - 0.018 14.7 6.3 1.8 8.2 0.2 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD RasGAP_C PF03836.10 GAO87545.1 - 0.027 14.1 4.5 0.045 13.4 3.1 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Seryl_tRNA_N PF02403.17 GAO87545.1 - 0.041 13.9 1.7 0.072 13.1 1.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 GAO87545.1 - 0.057 13.2 1.1 0.12 12.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_C PF12806.2 GAO87545.1 - 0.06 13.2 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Baculo_PEP_C PF04513.7 GAO87545.1 - 0.078 12.8 7.0 0.068 12.9 1.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fmp27_WPPW PF10359.4 GAO87545.1 - 0.079 11.3 4.0 0.11 10.9 2.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 GAO87545.1 - 0.14 11.3 3.7 0.21 10.7 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TraQ PF09679.5 GAO87545.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) CENP-F_leu_zip PF10473.4 GAO87545.1 - 0.2 11.5 5.5 0.3 10.9 3.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.7 GAO87545.1 - 0.22 11.5 2.7 0.56 10.2 1.2 1.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG AAA_32 PF13654.1 GAO87545.1 - 0.23 10.0 3.6 1.6 7.3 0.2 2.0 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 GAO87545.1 - 1.7 8.2 7.6 0.15 11.5 2.0 1.6 2 0 0 2 2 2 0 IncA protein COG2 PF06148.6 GAO87545.1 - 2.7 7.8 6.0 4 7.3 2.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 I_LWEQ PF01608.12 GAO87545.1 - 8.7 6.2 7.6 1.2 9.0 0.9 2.1 2 0 0 2 2 2 0 I/LWEQ domain PHD PF00628.24 GAO87546.1 - 3e-18 65.2 18.3 6.6e-12 44.9 4.2 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 GAO87546.1 - 0.0071 16.0 7.0 0.23 11.2 0.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 GAO87546.1 - 0.022 14.0 8.3 0.27 10.4 1.6 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 GAO87546.1 - 0.033 13.4 10.3 0.4 10.0 0.8 3.2 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 GAO87546.1 - 0.052 13.7 3.0 6 7.0 0.4 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 GAO87546.1 - 0.2 11.3 8.6 0.47 10.2 0.4 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M24 PF00557.19 GAO87547.1 - 5.2e-12 45.7 0.1 7.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 GAO87548.1 - 2.2e-09 37.6 1.1 4.6e-09 36.5 0.8 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 GAO87549.1 - 5e-81 271.7 0.3 8.5e-81 271.0 0.2 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 SOBP PF15279.1 GAO87549.1 - 2.3 8.5 23.5 0.41 10.9 12.8 2.2 2 1 0 2 2 2 0 Sine oculis-binding protein HEAT_2 PF13646.1 GAO87551.1 - 1.1e-09 38.4 8.5 9e-07 29.0 0.4 5.9 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 GAO87551.1 - 2.7e-05 24.5 9.7 0.016 15.6 0.1 6.1 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.17 GAO87551.1 - 7.8e-05 22.4 12.4 0.052 13.6 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat RIX1 PF08167.7 GAO87551.1 - 0.00018 21.2 0.2 1.1 8.9 0.0 4.6 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Nop14 PF04147.7 GAO87551.1 - 1.3 6.8 42.2 0.72 7.7 0.0 2.6 2 0 0 2 2 2 0 Nop14-like family MFS_1 PF07690.11 GAO87552.1 - 2.6e-42 144.8 41.0 2.6e-42 144.8 28.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PHD PF00628.24 GAO87553.1 - 2e-11 43.4 11.3 8e-11 41.4 2.9 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 GAO87553.1 - 7.3e-10 38.5 0.6 7.3e-10 38.5 0.4 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAO87553.1 - 9.5e-07 28.7 0.6 9.5e-07 28.7 0.4 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO87553.1 - 1.1e-06 28.1 0.4 1.1e-06 28.1 0.3 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO87553.1 - 2e-06 27.4 0.2 2e-06 27.4 0.1 3.0 4 0 0 4 4 4 1 zinc-RING finger domain PHD_2 PF13831.1 GAO87553.1 - 2.3e-06 26.8 1.4 4.7e-06 25.8 0.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.20 GAO87553.1 - 2.6e-06 26.9 0.2 2.6e-06 26.9 0.1 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO87553.1 - 2.2e-05 24.4 3.3 2.2e-05 24.4 2.3 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 GAO87553.1 - 5.1e-05 22.7 4.3 0.0012 18.3 0.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 GAO87553.1 - 0.0044 16.8 0.1 0.0044 16.8 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.1 GAO87553.1 - 0.016 14.8 4.6 0.19 11.4 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rtf2 PF04641.7 GAO87553.1 - 0.087 12.0 1.5 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.1 GAO87553.1 - 0.12 11.9 2.1 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 GAO87553.1 - 0.22 11.3 5.5 19 5.2 2.6 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_UBOX PF13445.1 GAO87553.1 - 0.59 9.9 8.1 0.28 10.9 1.8 3.0 2 1 0 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.1 GAO87553.1 - 1.5 8.5 8.1 0.19 11.5 0.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RanBP PF00641.13 GAO87553.1 - 3.9 6.6 8.1 4 6.6 0.0 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Ribosomal_L37ae PF01780.14 GAO87554.1 - 6.4e-41 138.1 10.6 7e-41 137.9 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 GAO87554.1 - 0.00098 18.8 2.5 0.0015 18.2 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 GAO87554.1 - 0.0021 17.4 3.7 0.14 11.6 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain GCC2_GCC3 PF07699.8 GAO87554.1 - 0.096 12.2 0.6 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 zf-BED PF02892.10 GAO87554.1 - 0.097 12.4 5.4 1.2 8.8 0.4 2.4 1 1 1 2 2 2 0 BED zinc finger Sgf11 PF08209.6 GAO87554.1 - 0.13 11.5 0.5 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NOB1_Zn_bind PF08772.6 GAO87554.1 - 0.16 11.8 3.2 1.5 8.6 2.4 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.5 GAO87554.1 - 0.18 11.7 1.6 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain CarbpepA_inh PF02977.10 GAO87554.1 - 0.65 9.6 5.3 0.42 10.2 0.5 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 GAO87554.1 - 0.72 10.3 3.4 7.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO87554.1 - 3.3 8.1 6.7 4.3 7.8 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Saccharop_dh PF03435.13 GAO87555.1 - 1.1e-21 77.3 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAO87555.1 - 0.096 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 GAO87556.1 - 4.5e-32 111.7 0.0 7.6e-32 111.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO87556.1 - 6.7e-20 71.6 0.1 2.3e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO87556.1 - 6.3e-10 38.9 0.0 2.1e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAO87556.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 GAO87556.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 GAO87556.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Pinin_SDK_memA PF04696.8 GAO87557.1 - 9.6e-32 109.3 15.4 9.6e-32 109.3 10.7 2.1 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Cofilin_ADF PF00241.15 GAO87557.1 - 6.2e-19 68.1 0.0 1.6e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein OTCace_N PF02729.16 GAO87557.1 - 0.28 10.8 2.3 0.28 10.8 0.6 1.7 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Mito_carr PF00153.22 GAO87558.1 - 9.8e-69 227.1 3.3 9.3e-23 79.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4137 PF13593.1 GAO87559.1 - 1.7e-90 303.2 15.6 2.1e-90 302.9 10.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Rox3 PF08633.5 GAO87560.1 - 0.073 13.3 4.7 0.13 12.5 3.3 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit Peptidase_S30 PF01577.11 GAO87560.1 - 0.3 10.4 6.6 0.46 9.8 4.6 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease DUF572 PF04502.8 GAO87560.1 - 0.81 8.8 11.6 1.3 8.1 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mucin PF01456.12 GAO87560.1 - 2.4 7.8 6.2 0.37 10.5 1.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein CAF1 PF04857.15 GAO87561.1 - 5.6e-49 166.8 0.1 8.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease MRP-L46 PF11788.3 GAO87561.1 - 2.5e-35 121.4 0.7 2.5e-35 121.4 0.5 2.5 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 GAO87561.1 - 1.4e-05 24.7 0.0 0.00027 20.5 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain DNA_pol_A_exo1 PF01612.15 GAO87561.1 - 0.019 14.4 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 3'-5' exonuclease Cript PF10235.4 GAO87562.1 - 8.6e-38 128.5 1.7 8.6e-38 128.5 1.2 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 GAO87562.1 - 0.0003 20.5 10.3 0.013 15.3 5.8 2.6 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 GAO87562.1 - 0.012 14.7 6.8 1.5 8.1 0.2 3.3 2 1 1 3 3 3 0 zinc-ribbon domain eIF-4B PF06273.6 GAO87562.1 - 0.051 12.3 0.7 0.053 12.2 0.5 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Prok-RING_4 PF14447.1 GAO87562.1 - 0.23 11.0 3.4 3.1 7.4 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.1 GAO87562.1 - 0.87 9.1 11.7 5.4 6.6 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 GAO87562.1 - 3.3 7.4 13.8 33 4.2 0.1 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 GAO87562.1 - 3.4 7.2 8.9 0.91 9.0 4.0 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-TFIIB PF13453.1 GAO87562.1 - 5.5 6.2 8.3 3.1 7.0 0.0 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger DUF581 PF04570.9 GAO87562.1 - 5.6 6.3 12.2 11 5.4 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF581) zf-HYPF PF07503.7 GAO87562.1 - 6.6 6.2 12.1 10 5.6 5.0 2.4 2 1 0 2 2 2 0 HypF finger DUF1272 PF06906.6 GAO87562.1 - 7.6 6.4 12.5 11 5.9 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 GAO87562.1 - 8.9 6.1 13.0 70 3.2 0.0 2.9 2 1 1 3 3 3 0 zinc-RING finger domain Shisa PF13908.1 GAO87563.1 - 0.00041 20.5 0.5 0.00096 19.3 0.4 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1349 PF07081.6 GAO87564.1 - 4e-16 58.8 0.0 3.4e-14 52.6 0.0 3.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1349) NOC3p PF07540.6 GAO87567.1 - 4.9e-36 122.9 0.4 4.9e-36 122.9 0.3 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 GAO87567.1 - 4e-32 110.9 2.0 5.5e-32 110.4 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Cullin_binding PF03556.10 GAO87568.1 - 3.4e-31 107.8 0.7 4.9e-31 107.2 0.5 1.2 1 0 0 1 1 1 1 Cullin binding UPF0113 PF03657.8 GAO87568.1 - 1.9e-06 27.6 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 GAO87568.1 - 0.00013 21.5 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 PUA domain Mpv17_PMP22 PF04117.7 GAO87569.1 - 5.1e-14 51.6 0.6 4.8e-12 45.3 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family PEX11 PF05648.9 GAO87571.1 - 9.2e-15 54.5 0.4 3.5e-13 49.3 0.3 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PrsW-protease PF13367.1 GAO87571.1 - 0.2 10.8 0.0 0.2 10.8 0.0 1.8 2 1 0 3 3 3 0 Protease prsW family AAA PF00004.24 GAO87572.1 - 5.3e-98 324.3 0.0 1.4e-47 161.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAO87572.1 - 8.2e-20 70.5 1.1 2.4e-19 69.0 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 GAO87572.1 - 2.2e-14 53.7 0.0 1.3e-07 31.6 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAO87572.1 - 2.2e-13 49.8 0.0 9.5e-06 24.8 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAO87572.1 - 1.3e-12 47.7 0.0 1.7e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAO87572.1 - 2.4e-12 46.7 0.6 5.6e-06 26.1 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAO87572.1 - 7.3e-12 45.5 0.3 0.0018 18.3 0.1 4.3 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAO87572.1 - 1.7e-11 45.0 0.0 0.00057 20.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO87572.1 - 7.7e-11 42.3 0.2 0.0019 18.2 0.0 3.8 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 GAO87572.1 - 1.5e-09 37.0 0.2 0.0009 18.0 0.0 2.8 3 0 0 3 3 3 2 TIP49 C-terminus CDC48_2 PF02933.12 GAO87572.1 - 6.9e-09 35.2 0.0 2.2e-08 33.6 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 GAO87572.1 - 3.4e-08 33.4 0.0 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO87572.1 - 4.8e-08 32.6 5.0 0.034 13.5 0.0 4.7 3 2 2 5 5 4 2 AAA domain Zeta_toxin PF06414.7 GAO87572.1 - 5.7e-08 32.0 0.0 0.0091 15.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 GAO87572.1 - 8.5e-08 31.8 0.0 0.0076 15.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAO87572.1 - 1.3e-07 31.0 0.8 0.0085 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAO87572.1 - 1.5e-07 31.0 1.2 0.0085 15.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 GAO87572.1 - 4.3e-07 30.0 0.0 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 GAO87572.1 - 1.4e-06 27.6 0.9 0.45 9.6 0.0 3.6 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 GAO87572.1 - 2.3e-06 27.5 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 GAO87572.1 - 4.4e-06 27.0 0.0 0.085 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 GAO87572.1 - 4.5e-06 26.3 0.0 0.094 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAO87572.1 - 8.3e-06 25.8 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 GAO87572.1 - 8.6e-06 24.8 0.0 0.011 14.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 GAO87572.1 - 1.3e-05 24.2 0.1 0.047 12.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 GAO87572.1 - 2.2e-05 24.0 0.1 0.26 10.7 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 GAO87572.1 - 2.6e-05 23.9 0.1 0.087 12.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 GAO87572.1 - 2.9e-05 23.8 1.0 5.6 6.5 0.0 4.2 3 2 2 5 5 4 0 Archaeal ATPase Vps4_C PF09336.5 GAO87572.1 - 3.9e-05 23.4 0.1 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 GAO87572.1 - 4.7e-05 23.1 0.0 0.25 10.9 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 GAO87572.1 - 8.7e-05 22.5 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAO87572.1 - 0.00011 22.5 0.0 0.34 11.1 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 GAO87572.1 - 0.00017 20.9 0.4 0.54 9.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 GAO87572.1 - 0.00022 20.8 0.0 0.88 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAO87572.1 - 0.00038 20.0 0.0 0.52 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 GAO87572.1 - 0.0005 19.7 0.0 1.2 8.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAO87572.1 - 0.0013 17.6 0.2 0.62 8.8 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 GAO87572.1 - 0.0014 18.1 0.0 0.3 10.5 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAO87572.1 - 0.0017 17.4 0.0 1.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 GAO87572.1 - 0.0021 17.7 0.4 1.1 8.9 0.0 3.9 4 0 0 4 4 3 1 NTPase KAP_NTPase PF07693.9 GAO87572.1 - 0.0084 15.1 0.3 0.95 8.3 0.0 3.2 2 2 1 4 4 4 1 KAP family P-loop domain AAA_10 PF12846.2 GAO87572.1 - 0.0096 15.3 0.6 1.6 8.0 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain IPT PF01745.11 GAO87572.1 - 0.014 14.6 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 GAO87572.1 - 0.039 13.4 0.7 12 5.3 0.1 4.1 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.11 GAO87572.1 - 0.083 11.6 0.0 10 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 GAO87572.1 - 0.098 12.2 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 GAO87572.1 - 0.42 10.4 2.8 9 6.1 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase EnY2 PF10163.4 GAO87573.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 SpoVR PF04293.8 GAO87573.1 - 1.1 7.5 4.1 2.8 6.2 0.1 2.0 2 0 0 2 2 2 0 SpoVR like protein SAM_2 PF07647.12 GAO87574.1 - 4.1e-17 61.7 0.0 1.1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAO87574.1 - 4.6e-16 58.7 0.0 9.9e-16 57.6 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 GAO87574.1 - 7.3e-15 55.2 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain MFS_1 PF07690.11 GAO87576.1 - 3.7e-37 127.8 56.0 3.7e-37 127.8 38.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO87576.1 - 3.8e-13 48.5 21.6 5.2e-13 48.0 15.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ins_allergen_rp PF06757.8 GAO87577.1 - 0.071 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification MucBP PF06458.7 GAO87578.1 - 0.54 10.8 6.3 9.7 6.8 0.2 2.7 1 1 1 2 2 2 0 MucBP domain Phage_int_SAM_5 PF13102.1 GAO87578.1 - 3.7 7.5 6.2 1.9 8.4 0.3 2.6 3 1 0 3 3 3 0 Phage integrase SAM-like domain DUF1080 PF06439.6 GAO87579.1 - 2.9e-15 56.6 0.0 1.3e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 GAO87579.1 - 0.0016 18.5 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 GAO87579.1 - 0.015 15.2 0.1 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain Laminin_G_3 PF13385.1 GAO87579.1 - 0.016 15.4 15.9 0.15 12.3 0.9 3.3 2 1 2 4 4 4 0 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_18 PF00704.23 GAO87580.1 - 1.7e-33 116.5 0.2 4e-33 115.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAO87580.1 - 1.9e-06 27.7 2.0 1.9e-06 27.7 1.4 3.1 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 GAO87580.1 - 2e-06 27.5 0.0 0.069 13.0 0.0 2.7 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 GAO87580.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) KAP_NTPase PF07693.9 GAO87581.1 - 0.0034 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 GAO87581.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAO87581.1 - 0.022 14.9 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAO87581.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAO87581.1 - 0.055 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CNTF PF01110.12 GAO87581.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_17 PF13207.1 GAO87581.1 - 0.089 13.6 0.0 0.66 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 GAO87581.1 - 0.09 12.5 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 OTT_1508_deam PF14441.1 GAO87582.1 - 9.4e-07 28.7 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase ABC_tran PF00005.22 GAO87583.1 - 4.4e-17 62.6 0.0 5.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 GAO87583.1 - 1.5e-06 27.5 0.2 1.9e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO87583.1 - 6.9e-06 26.2 0.0 7.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAO87583.1 - 0.068 13.0 0.1 0.28 11.1 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 GAO87584.1 - 1.3e-31 110.0 30.0 1.1e-22 80.8 8.1 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO87584.1 - 1.6e-16 60.8 0.0 3e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 GAO87584.1 - 7e-07 29.4 0.0 0.00012 22.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO87584.1 - 0.0033 17.3 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAO87584.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 GAO87584.1 - 0.024 14.2 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 GAO87584.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAO87584.1 - 0.043 13.2 0.1 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAO87584.1 - 0.074 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 GAO87584.1 - 0.075 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAO87584.1 - 0.093 13.5 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 GAO87584.1 - 0.18 10.4 0.1 0.28 9.8 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 GAO87584.1 - 0.45 10.7 0.5 0.83 9.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain PID PF00640.18 GAO87585.1 - 0.0035 17.3 0.1 1.3e+02 2.4 0.0 5.1 6 0 0 6 6 6 0 Phosphotyrosine interaction domain (PTB/PID) Gla PF00594.15 GAO87585.1 - 0.0039 16.8 11.3 60 3.4 0.0 6.1 6 0 0 6 6 6 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain RTC4 PF14474.1 GAO87585.1 - 0.012 15.5 1.0 5.4 6.9 0.2 2.8 1 1 1 2 2 2 0 RTC4-like domain XhoI PF04555.8 GAO87585.1 - 0.034 13.5 0.8 21 4.4 0.0 3.1 1 1 2 3 3 3 0 Restriction endonuclease XhoI Mso1_Sec1_bdg PF14475.1 GAO87585.1 - 0.31 10.4 8.8 45 3.5 0.0 5.0 1 1 5 6 6 6 0 Sec1-binding region of Mso1 Myco_arth_vir_N PF09610.5 GAO87585.1 - 0.65 10.0 3.1 1.3 9.0 2.1 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Prok-TraM PF09228.5 GAO87585.1 - 1.1 9.3 6.7 11 6.2 0.2 2.9 1 1 2 3 3 3 0 Prokaryotic Transcriptional repressor TraM PqqD PF05402.7 GAO87585.1 - 1.6 8.7 8.5 30 4.7 0.1 3.9 2 1 3 5 5 5 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3328 PF11807.3 GAO87586.1 - 8.2e-47 159.6 1.0 1.1e-46 159.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PAS_3 PF08447.6 GAO87586.1 - 0.038 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF3328 PF11807.3 GAO87587.1 - 4.5e-43 147.4 0.8 5.9e-43 147.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 GAO87588.1 - 3e-20 72.2 34.2 6.2e-17 61.3 12.1 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 GAO87588.1 - 0.00046 18.3 0.3 0.001 17.2 0.1 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.7 GAO87589.1 - 1.6e-05 24.5 0.1 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Nha1_C PF08619.5 GAO87591.1 - 4.2e-122 408.5 32.4 5.2e-122 408.2 22.5 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 GAO87591.1 - 7.4e-68 228.8 14.0 9.3e-68 228.4 9.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAO87591.1 - 0.37 10.7 1.1 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 GAO87591.1 - 0.37 10.0 7.4 0.043 13.1 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF21 PX PF00787.19 GAO87592.1 - 5.5e-18 64.7 0.2 1.3e-17 63.6 0.2 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 GAO87592.1 - 0.02 13.5 0.6 0.037 12.6 0.4 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein V-SNARE_C PF12352.3 GAO87592.1 - 0.11 12.6 1.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Prefoldin_3 PF13758.1 GAO87592.1 - 0.32 10.7 4.0 0.18 11.5 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Utp8 PF10395.4 GAO87594.1 - 0.041 12.2 1.6 1.8 6.7 0.1 2.5 2 1 0 2 2 2 0 Utp8 family Fungal_trans PF04082.13 GAO87595.1 - 2e-22 79.2 0.2 3.7e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO87595.1 - 1.3e-10 40.9 13.8 5.7e-05 23.2 1.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO87595.1 - 1.1e-06 28.5 19.1 1.3e-06 28.3 4.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO87595.1 - 0.00044 20.3 18.6 0.023 14.9 2.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO87595.1 - 0.17 12.0 3.3 0.19 11.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAO87595.1 - 0.32 10.9 7.1 2.7 8.0 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 GAO87595.1 - 5.9 7.2 8.0 1.2 9.4 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Glyco_hydro_62 PF03664.8 GAO87596.1 - 9.2e-149 493.9 9.4 1.1e-148 493.7 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Abhydrolase_6 PF12697.2 GAO87597.1 - 7.1e-23 81.6 0.0 8.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87597.1 - 2.5e-06 27.3 0.0 3.5e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO87597.1 - 0.0032 17.1 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 GAO87597.1 - 0.033 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 GAO87597.1 - 0.074 12.5 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold TPR_12 PF13424.1 GAO87598.1 - 9.4e-151 490.1 57.3 9.4e-18 63.9 0.8 11.5 4 3 8 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.1 GAO87598.1 - 2.1e-140 453.2 43.2 8.2e-11 41.4 0.0 17.6 17 0 0 17 17 17 17 Tetratricopeptide repeat TPR_1 PF00515.23 GAO87598.1 - 4.8e-63 206.3 66.0 6.9e-05 22.2 0.4 17.5 17 0 0 17 17 17 14 Tetratricopeptide repeat TPR_7 PF13176.1 GAO87598.1 - 1.5e-62 202.5 41.5 0.00074 19.1 0.0 17.5 17 0 0 17 17 17 14 Tetratricopeptide repeat TPR_2 PF07719.12 GAO87598.1 - 2.6e-48 158.0 59.8 0.00077 19.1 0.3 17.3 17 0 0 17 17 17 14 Tetratricopeptide repeat TPR_11 PF13414.1 GAO87598.1 - 1.1e-46 156.3 43.8 1.7e-06 27.5 1.4 12.2 4 3 8 13 13 13 13 TPR repeat TPR_14 PF13428.1 GAO87598.1 - 1.1e-46 152.9 35.3 0.034 14.7 0.1 17.9 9 4 8 17 17 17 14 Tetratricopeptide repeat TPR_16 PF13432.1 GAO87598.1 - 2.1e-39 133.3 42.6 2.9e-06 27.7 0.8 13.4 10 4 3 14 14 13 9 Tetratricopeptide repeat TPR_8 PF13181.1 GAO87598.1 - 1.4e-38 127.7 45.6 0.013 15.1 0.1 16.4 16 0 0 16 16 16 13 Tetratricopeptide repeat TPR_17 PF13431.1 GAO87598.1 - 4.2e-21 73.3 26.6 0.82 10.0 0.0 17.0 17 0 0 17 17 17 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAO87598.1 - 1e-19 68.8 0.1 3.2 8.4 0.2 15.3 17 0 0 17 17 16 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAO87598.1 - 4.9e-17 61.6 0.1 8.6e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_19 PF14559.1 GAO87598.1 - 1.3e-14 54.2 40.3 0.14 12.5 0.1 11.5 6 3 4 12 12 12 7 Tetratricopeptide repeat TPR_21 PF09976.4 GAO87598.1 - 1.6e-14 54.0 20.3 0.82 9.6 0.1 12.8 13 2 2 15 15 15 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAO87598.1 - 1.5e-12 46.9 0.0 2.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2225 PF09986.4 GAO87598.1 - 3.5e-12 46.2 6.6 0.073 12.5 0.0 6.8 1 1 4 7 7 7 5 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 GAO87598.1 - 6.9e-11 41.8 5.1 0.14 11.2 0.2 6.7 4 3 2 7 7 7 3 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 GAO87598.1 - 2.7e-09 36.8 62.7 1.1 9.9 0.0 16.2 16 0 0 16 16 16 2 Tetratricopeptide repeat PPR PF01535.15 GAO87598.1 - 4.6e-09 35.6 10.9 16 5.7 0.0 12.6 14 0 0 14 14 14 0 PPR repeat Apc3 PF12895.2 GAO87598.1 - 4.1e-08 33.2 24.3 0.023 14.8 0.1 7.9 2 2 7 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 GAO87598.1 - 0.0027 17.7 0.0 0.019 14.9 0.0 2.6 3 0 0 3 3 1 1 AAA ATPase domain SPO22 PF08631.5 GAO87598.1 - 0.21 10.6 1.2 28 3.6 0.0 4.8 7 0 0 7 7 7 0 Meiosis protein SPO22/ZIP4 like PPR_2 PF13041.1 GAO87598.1 - 0.97 9.4 11.8 1.2e+02 2.7 0.0 7.9 11 0 0 11 11 9 0 PPR repeat family Lipase_GDSL_2 PF13472.1 GAO87600.1 - 4.2e-19 69.3 3.4 5.8e-19 68.9 2.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO87600.1 - 1.1e-12 48.3 0.7 1.6e-12 47.7 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Metallophos PF00149.23 GAO87601.1 - 2.6e-13 49.8 2.5 5.1e-13 48.8 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO87601.1 - 0.00018 21.4 0.0 0.00029 20.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3632 PF12311.3 GAO87602.1 - 1.8e-39 135.4 0.0 2.6e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MFS_1 PF07690.11 GAO87603.1 - 1e-19 70.4 49.5 2e-10 39.9 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAO87603.1 - 0.019 14.9 9.0 1.4 8.9 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Glyco_transf_90 PF05686.7 GAO87604.1 - 4.9e-28 97.9 0.3 6.5e-28 97.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 GAO87604.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 PNP_UDP_1 PF01048.15 GAO87605.1 - 1.2e-08 34.2 0.0 3e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAO87605.1 - 7.6e-08 32.1 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAO87605.1 - 6.5e-05 23.0 0.1 0.00076 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO87605.1 - 0.00059 19.8 0.0 0.002 18.1 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAO87605.1 - 0.0025 17.9 0.0 0.0065 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Torsin PF06309.6 GAO87605.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_10 PF12846.2 GAO87605.1 - 0.025 13.9 0.1 0.07 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 GAO87605.1 - 0.098 12.8 0.0 0.89 9.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 GAO87606.1 - 1.9e-73 242.8 1.3 3.3e-19 69.0 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87606.1 - 1.7e-61 201.0 3.3 4.2e-08 32.6 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 GAO87606.1 - 1.6e-51 167.0 0.7 1.3e-06 28.0 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAO87606.1 - 1.9e-47 158.8 0.1 2.1e-10 40.8 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO87606.1 - 2.6e-36 122.8 5.7 4.2e-07 30.0 0.1 7.9 3 3 5 8 8 8 8 Ankyrin repeats (many copies) DUF3881 PF12997.2 GAO87606.1 - 0.042 12.8 0.1 4.4 6.2 0.0 3.2 1 1 3 4 4 4 0 Domain of unknown function, E. rectale Gene description (DUF3881) G6B PF15096.1 GAO87606.1 - 0.043 13.3 0.0 6.1 6.2 0.0 3.8 5 0 0 5 5 5 0 G6B family Phosphonate-bd PF12974.2 GAO87606.1 - 0.1 11.9 0.6 31 3.8 0.1 3.1 1 1 2 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GNVR PF13807.1 GAO87606.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase WD40 PF00400.27 GAO87607.1 - 1.2e-59 196.1 9.3 5.3e-12 45.1 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Pectate_lyase_3 PF12708.2 GAO87607.1 - 3.6e-12 46.8 1.1 5.6e-12 46.2 0.1 1.7 2 0 0 2 2 2 1 Pectate lyase superfamily protein PQQ_2 PF13360.1 GAO87607.1 - 1.9e-06 27.5 4.9 8.5e-05 22.1 1.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 GAO87607.1 - 0.00075 17.7 4.3 0.11 10.6 0.3 4.2 1 1 4 5 5 5 1 Nucleoporin Nup120/160 F-box-like PF12937.2 GAO87607.1 - 0.0011 18.6 0.3 0.0032 17.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like Me-amine-dh_H PF06433.6 GAO87607.1 - 0.0054 15.4 0.0 0.051 12.1 0.0 2.2 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 GAO87607.1 - 0.0074 14.6 0.1 1.6 6.9 0.0 2.4 1 1 0 2 2 2 2 Cytochrome D1 heme domain F-box PF00646.28 GAO87607.1 - 0.073 12.7 0.7 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 F-box domain GST_N PF02798.15 GAO87609.1 - 1.5e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO87609.1 - 1.6e-07 31.3 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO87609.1 - 6.6e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO87609.1 - 2.1e-06 27.4 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO87609.1 - 2.8e-05 24.5 0.0 3.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO87609.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ECIST_Cterm PF14784.1 GAO87612.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein TrkH PF02386.11 GAO87614.1 - 5.1e-109 364.0 9.3 1.5e-105 352.6 2.0 2.3 2 0 0 2 2 2 2 Cation transport protein Fringe PF02434.11 GAO87615.1 - 0.00012 21.4 1.5 0.0014 17.8 1.1 2.3 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 GAO87615.1 - 0.0017 18.0 0.2 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 GAO87615.1 - 0.027 14.1 1.0 0.068 12.8 0.7 1.7 1 0 0 1 1 1 0 PAN domain Peptidase_S28 PF05577.7 GAO87616.1 - 7e-51 173.1 0.0 1e-50 172.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_3 PF07859.8 GAO87617.1 - 1.1e-15 57.8 0.4 2.5e-07 30.4 0.1 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 GAO87617.1 - 4.1e-05 22.9 0.1 0.00085 18.6 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAO87617.1 - 9.6e-05 21.6 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CCD PF07860.6 GAO87617.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 WisP family C-Terminal Region MFS_1 PF07690.11 GAO87618.1 - 1.9e-28 99.2 54.4 2.4e-16 59.3 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87618.1 - 2.6e-05 22.9 32.6 0.0053 15.3 5.5 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter DUF106 PF01956.11 GAO87618.1 - 0.048 13.1 0.1 0.18 11.3 0.1 1.9 1 0 0 1 1 1 0 Integral membrane protein DUF106 Choline_kinase PF01633.15 GAO87620.1 - 9.9e-22 77.5 0.2 3.9e-21 75.5 0.0 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAO87620.1 - 2.2e-07 30.8 0.0 3.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FAD_binding_4 PF01565.18 GAO87621.1 - 5.4e-23 81.0 1.9 8.9e-23 80.2 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain CorA PF01544.13 GAO87621.1 - 6.1e-05 22.1 0.1 0.00013 21.1 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_C50 PF03568.12 GAO87621.1 - 0.042 12.5 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 DUF3472 PF11958.3 GAO87622.1 - 3.3e-14 53.6 0.3 4.2e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) PNP_UDP_1 PF01048.15 GAO87623.1 - 1.1e-14 54.0 0.2 7.3e-14 51.2 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 GAO87623.1 - 5.1e-07 28.8 0.0 7.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAO87623.1 - 0.0001 22.4 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain BACK PF07707.10 GAO87623.1 - 0.014 15.2 0.5 0.036 13.8 0.4 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch NMO PF03060.10 GAO87624.1 - 2.5e-43 148.4 2.9 1.2e-33 116.6 0.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 GAO87624.1 - 3.2e-07 29.5 2.7 5e-07 28.8 1.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAO87624.1 - 4.9e-07 28.9 0.0 0.025 13.4 1.2 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO87624.1 - 0.00065 18.7 0.1 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Amidohydro_2 PF04909.9 GAO87625.1 - 3.7e-44 151.3 0.2 4.5e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 GAO87626.1 - 3.4e-151 503.7 0.0 4.2e-151 503.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 3-HAO PF06052.7 GAO87626.1 - 1e-48 164.5 0.0 1.8e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAO87626.1 - 1.2e-05 24.6 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Ribonuc_L-PSP PF01042.16 GAO87627.1 - 4.2e-18 65.2 0.0 6.4e-18 64.6 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Stap_Strp_toxin PF01123.15 GAO87628.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain TRP PF06011.7 GAO87629.1 - 4.7e-24 84.7 16.0 1.2e-22 80.1 11.1 2.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel RseC_MucC PF04246.7 GAO87629.1 - 3.2 7.3 8.6 0.71 9.4 0.1 3.2 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Aa_trans PF01490.13 GAO87630.1 - 2.1e-42 145.0 37.4 2.5e-42 144.7 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 GAO87630.1 - 0.00024 19.8 22.6 0.00024 19.8 15.7 2.2 2 0 0 2 2 2 1 Spore germination protein Neurensin PF14927.1 GAO87630.1 - 0.52 9.6 6.4 0.64 9.4 2.0 2.5 2 0 0 2 2 2 0 Neurensin Wzy_C PF04932.10 GAO87630.1 - 5.9 6.6 15.6 5.1 6.8 4.7 3.2 3 0 0 3 3 3 0 O-Antigen ligase CN_hydrolase PF00795.17 GAO87631.1 - 2.6e-34 118.1 0.0 4.3e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pyr_redox_3 PF13738.1 GAO87631.1 - 2.9e-29 102.6 0.0 7.3e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO87631.1 - 1.9e-20 72.5 0.0 2.6e-19 68.8 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO87631.1 - 2.6e-09 36.4 0.1 6e-08 31.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO87631.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87631.1 - 3.6e-07 30.1 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO87631.1 - 2.7e-06 26.5 0.0 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 GAO87631.1 - 0.00012 21.1 0.1 0.00038 19.4 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_7 PF13241.1 GAO87631.1 - 0.0005 20.2 0.0 0.025 14.8 0.0 3.3 4 0 0 4 4 4 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAO87631.1 - 0.00076 19.2 0.0 0.01 15.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO87631.1 - 0.0033 17.8 0.5 1.2 9.6 0.0 3.5 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO87631.1 - 0.008 15.0 0.0 0.021 13.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Gal4_dimer PF03902.8 GAO87631.1 - 0.0091 15.9 0.1 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 Gal4-like dimerisation domain Thi4 PF01946.12 GAO87631.1 - 0.021 13.9 0.1 0.076 12.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 GAO87631.1 - 0.047 13.7 0.0 2.4 8.2 0.0 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_4 PF13420.1 GAO87632.1 - 2.9e-14 53.2 0.0 1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO87632.1 - 3.3e-06 27.2 0.0 7.9e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO87632.1 - 1.4e-05 25.2 0.0 2.2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO87632.1 - 2.2e-05 24.5 0.0 5.5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO87632.1 - 2.9e-05 23.9 0.0 0.00078 19.3 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO87632.1 - 7.3e-05 22.7 0.2 0.00043 20.2 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Cu-oxidase_3 PF07732.10 GAO87634.1 - 9.4e-42 141.4 1.1 4e-41 139.4 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO87634.1 - 6.5e-26 90.4 4.7 6.7e-23 80.7 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO87634.1 - 1.3e-21 77.1 0.0 1.3e-18 67.3 0.0 2.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO87635.1 - 4.1e-35 121.0 1.5 1.8e-34 118.9 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAO87635.1 - 3.2e-34 117.1 4.7 5.9e-24 84.0 0.1 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO87635.1 - 1.2e-20 73.4 6.8 9.8e-20 70.4 0.5 2.9 2 1 0 2 2 2 2 Multicopper oxidase DUF1100 PF06500.6 GAO87637.1 - 2.7e-13 49.2 0.0 3.4e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 GAO87637.1 - 2.2e-12 47.3 2.1 3e-12 46.9 0.8 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87637.1 - 4.9e-12 45.8 0.0 9.8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAO87637.1 - 8.7e-07 28.6 0.1 1.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAO87637.1 - 3.2e-06 26.5 0.0 9.6e-06 24.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 GAO87637.1 - 3.6e-05 23.5 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 GAO87637.1 - 4.2e-05 23.0 0.0 0.00015 21.2 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 GAO87637.1 - 0.0027 17.2 0.2 0.45 10.0 0.0 2.8 1 1 2 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.13 GAO87637.1 - 0.015 14.6 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 GAO87637.1 - 0.039 13.5 0.2 1.6 8.2 0.1 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold LIP PF03583.9 GAO87637.1 - 0.12 11.5 0.0 0.86 8.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase adh_short PF00106.20 GAO87638.1 - 1.2e-35 122.9 1.6 1.4e-35 122.6 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87638.1 - 4.7e-28 98.5 0.0 6e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87638.1 - 1.5e-20 73.6 0.5 2.1e-20 73.1 0.3 1.1 1 0 0 1 1 1 1 KR domain BURP PF03181.10 GAO87638.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 BURP domain Epimerase PF01370.16 GAO87638.1 - 0.041 13.3 0.4 0.11 11.8 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAO87638.1 - 0.042 12.9 0.2 0.44 9.6 0.1 2.1 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Scytalone_dh PF02982.9 GAO87639.1 - 1.2e-90 301.2 4.3 1.3e-90 301.0 2.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAO87639.1 - 9.5e-08 32.0 2.3 1.2e-07 31.6 1.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain ketoacyl-synt PF00109.21 GAO87640.1 - 9e-78 261.2 0.0 1.5e-77 260.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO87640.1 - 2.4e-52 178.2 0.0 4.4e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO87640.1 - 1.5e-33 115.1 1.4 1.1e-30 105.9 0.1 4.1 5 0 0 5 5 5 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAO87640.1 - 1.6e-28 100.5 0.0 4.7e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAO87640.1 - 1.7e-22 79.4 4.9 8.8e-12 45.1 0.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAO87640.1 - 3.3e-14 52.7 0.0 6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 GAO87640.1 - 3.8e-05 22.8 0.0 7.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 GAO87640.1 - 0.00021 21.2 0.0 0.064 13.1 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87640.1 - 0.00022 21.0 0.0 0.025 14.3 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Sulfatase PF00884.18 GAO87641.1 - 5.3e-23 81.6 0.4 9.3e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAO87641.1 - 2.7e-05 23.6 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAO87641.1 - 0.013 13.9 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) GMC_oxred_C PF05199.8 GAO87642.1 - 8.7e-27 94.1 0.4 1.6e-26 93.3 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAO87642.1 - 9.4e-27 93.9 0.2 3.4e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO87642.1 - 2.6e-10 39.7 0.9 0.00018 20.4 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO87642.1 - 7.3e-07 28.4 4.3 6.9e-06 25.2 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO87642.1 - 8.3e-07 28.9 0.1 1.9e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO87642.1 - 2.4e-05 24.4 0.6 0.032 14.2 0.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO87642.1 - 6.2e-05 22.9 0.1 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO87642.1 - 0.00025 21.3 0.3 0.9 9.9 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO87642.1 - 0.0011 17.5 0.2 0.0019 16.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAO87642.1 - 0.0019 17.3 0.9 0.015 14.3 0.6 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 GAO87642.1 - 0.017 14.1 0.3 0.18 10.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO87642.1 - 0.025 13.5 0.2 0.048 12.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 GAO87642.1 - 0.067 12.0 0.7 0.93 8.2 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 GAO87642.1 - 0.083 12.3 0.3 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HsbA PF12296.3 GAO87643.1 - 3.2e-32 110.9 13.1 3.2e-32 110.9 9.1 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A LPP PF04728.8 GAO87643.1 - 0.00062 19.5 7.3 0.038 13.7 0.2 3.3 2 1 1 3 3 3 2 Lipoprotein leucine-zipper Phage_GP20 PF06810.6 GAO87643.1 - 0.14 11.5 2.8 0.23 10.8 0.8 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Syntaxin_2 PF14523.1 GAO87643.1 - 0.16 11.9 2.2 0.24 11.4 0.4 1.9 2 0 0 2 2 2 0 Syntaxin-like protein NPV_P10 PF05531.7 GAO87643.1 - 0.27 11.5 6.8 0.69 10.2 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 GAO87643.1 - 0.57 10.3 2.6 1.8 8.7 1.3 1.9 1 1 1 2 2 2 0 Syntaxin MFS_1 PF07690.11 GAO87644.1 - 7.2e-34 117.0 38.4 7.2e-34 117.0 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87644.1 - 1.7e-14 53.2 5.7 1.7e-14 53.2 4.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2140 PF09911.4 GAO87644.1 - 0.12 11.5 1.9 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) TRP PF06011.7 GAO87645.1 - 2.4e-140 467.9 33.4 3.1e-140 467.6 23.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAO87645.1 - 7.6e-44 149.1 0.5 1.3e-43 148.4 0.4 1.4 1 0 0 1 1 1 1 ML-like domain Ank_2 PF12796.2 GAO87645.1 - 1.4e-35 121.4 0.1 2.3e-14 53.4 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87645.1 - 9.4e-34 113.5 3.6 4.9e-08 32.3 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAO87645.1 - 1.3e-29 101.5 1.0 9.1e-10 38.4 0.1 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO87645.1 - 2e-27 95.0 0.4 3.5e-11 43.3 0.1 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO87645.1 - 1.2e-20 71.4 0.6 0.00019 21.3 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat PNP_UDP_1 PF01048.15 GAO87645.1 - 4e-10 39.0 0.0 9.5e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily SLAC1 PF03595.12 GAO87646.1 - 5.4e-76 255.3 33.9 6.1e-76 255.1 23.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Renin_r PF07850.9 GAO87646.1 - 5.1 7.5 7.7 0.67 10.3 0.6 2.6 2 0 0 2 2 2 0 Renin receptor-like protein MFS_1 PF07690.11 GAO87647.1 - 2.9e-25 88.7 49.6 2e-24 85.9 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 GAO87648.1 - 1.4e-128 419.5 1.2 2.6e-19 69.3 0.1 7.9 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87648.1 - 3.1e-83 269.7 18.4 6.7e-07 28.8 0.0 15.9 16 1 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.1 GAO87648.1 - 4.9e-72 237.1 7.0 3.3e-09 37.0 0.0 11.6 6 3 6 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO87648.1 - 2.3e-66 218.3 14.8 2e-08 34.2 0.1 13.3 4 3 8 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO87648.1 - 8e-66 211.3 6.8 0.00014 21.7 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Shigella_OspC PF06128.6 GAO87648.1 - 0.21 11.0 0.0 85 2.5 0.0 4.2 4 1 1 6 6 6 0 Shigella flexneri OspC protein TPT PF03151.11 GAO87649.1 - 1.6e-16 60.3 24.2 9.6e-16 57.7 9.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 GAO87649.1 - 0.5 10.4 36.4 0.15 12.0 12.3 2.8 1 1 2 3 3 3 0 EamA-like transporter family Glyco_transf_25 PF01755.12 GAO87650.1 - 0.00019 21.1 0.0 0.031 13.9 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Aa_trans PF01490.13 GAO87651.1 - 2.2e-29 102.2 23.1 2.9e-29 101.7 16.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RTA1 PF04479.8 GAO87653.1 - 9.3e-31 107.0 3.2 1.5e-30 106.3 2.2 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4246 PF14033.1 GAO87654.1 - 2.6e-176 587.1 1.3 4.3e-176 586.4 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 GAO87654.1 - 0.018 15.2 0.0 0.059 13.6 0.0 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Methyltransf_2 PF00891.13 GAO87655.1 - 1.2e-20 73.7 0.0 2.1e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase EI24 PF07264.6 GAO87656.1 - 0.0011 18.4 0.1 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) MFS_1 PF07690.11 GAO87657.1 - 5.9e-30 104.1 40.1 5.9e-30 104.1 27.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HCV_NS4a PF01006.15 GAO87657.1 - 0.046 13.2 0.3 0.14 11.7 0.2 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Ank_2 PF12796.2 GAO87658.1 - 4.2e-98 321.8 0.1 9.7e-15 54.6 0.0 5.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87658.1 - 3.8e-55 181.0 0.0 8.5e-06 25.3 0.0 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 GAO87658.1 - 1.3e-53 178.4 6.5 4.1e-10 39.8 0.0 6.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO87658.1 - 2.8e-42 141.7 10.5 4.3e-08 33.1 0.0 7.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO87658.1 - 7e-40 131.0 0.0 0.0037 17.3 0.0 9.3 9 0 0 9 9 9 9 Ankyrin repeat DUF3734 PF12536.3 GAO87658.1 - 0.00026 21.0 0.2 6.1 7.0 0.0 5.1 2 2 3 6 6 6 1 Patatin phospholipase Phenol_monoox PF04663.7 GAO87658.1 - 0.052 13.2 0.0 14 5.5 0.0 2.9 3 0 0 3 3 3 0 Phenol hydroxylase conserved region DUF3017 PF11222.3 GAO87658.1 - 0.37 10.6 6.3 36 4.2 0.0 5.7 8 0 0 8 8 8 0 Protein of unknown function (DUF3017) Epimerase PF01370.16 GAO87659.1 - 1.4e-14 54.0 0.0 3e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO87659.1 - 5.6e-14 51.5 0.0 2.2e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO87659.1 - 1.7e-11 44.4 0.0 1.9e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO87659.1 - 1.3e-07 30.8 0.0 1.7e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAO87659.1 - 2.1e-05 23.8 0.0 0.00024 20.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAO87659.1 - 6e-05 22.0 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAO87659.1 - 0.00029 20.7 0.0 0.00083 19.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 GAO87660.1 - 4.9e-15 55.1 0.1 9.4e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAO87661.1 - 1.6e-21 76.9 0.0 2.2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO87661.1 - 6.8e-06 26.2 0.1 1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO87661.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO87661.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAO87661.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 GAO87661.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 GAO87661.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 GAO87661.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans_2 PF11951.3 GAO87662.1 - 0.0005 18.7 0.4 0.0024 16.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAO87663.1 - 2.4e-42 144.9 2.1 3.6e-42 144.4 1.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1746 PF08508.5 GAO87663.1 - 0.03 14.2 2.5 0.04 13.8 0.2 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Fungal_trans PF04082.13 GAO87664.1 - 9.9e-19 67.2 0.7 1.4e-18 66.7 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87664.1 - 1.6e-09 37.5 9.4 3.9e-09 36.2 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.6 GAO87665.1 - 3.2e-05 23.3 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Glyco_hydro_43 PF04616.9 GAO87666.1 - 3e-31 108.5 0.5 5.5e-31 107.7 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 GAO87668.1 - 9.6e-16 57.4 0.9 1.6e-15 56.7 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO87669.1 - 8.3e-43 146.4 61.9 5.6e-42 143.7 42.3 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO87669.1 - 1.6e-13 49.7 25.1 2.6e-13 49.0 17.4 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO87669.1 - 3.8e-13 48.8 7.7 3.8e-13 48.8 5.3 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.17 GAO87670.1 - 1.3e-56 192.0 0.0 1.7e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 GAO87671.1 - 9e-34 116.7 0.0 3.9e-33 114.6 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAO87671.1 - 1.3e-08 35.0 0.3 1.7e-08 34.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87671.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 GAO87671.1 - 0.056 12.8 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain ketoacyl-synt PF00109.21 GAO87672.1 - 2e-73 247.0 0.0 4.8e-73 245.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAO87672.1 - 5.5e-64 215.1 0.2 2e-63 213.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAO87672.1 - 6.5e-56 189.9 0.0 1.1e-55 189.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAO87672.1 - 9.6e-49 165.5 0.3 5.6e-48 163.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 GAO87672.1 - 3.8e-41 141.1 0.0 6.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAO87672.1 - 9.4e-39 131.9 0.0 2.4e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAO87672.1 - 1.1e-19 70.2 0.1 7.1e-19 67.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAO87672.1 - 1.6e-18 66.9 0.0 5.5e-18 65.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87672.1 - 1.3e-12 47.7 0.0 3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAO87672.1 - 2.2e-11 44.7 0.0 8.9e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAO87672.1 - 9e-09 35.0 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAO87672.1 - 2e-08 33.9 0.2 5.3e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 GAO87672.1 - 7.2e-08 32.8 0.0 2.5e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87672.1 - 1.6e-06 28.6 0.0 5.7e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO87672.1 - 0.0011 17.9 0.0 0.0036 16.3 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain PCMT PF01135.14 GAO87672.1 - 0.003 17.1 0.0 0.21 11.0 0.0 2.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAO87672.1 - 0.0032 17.4 0.0 0.013 15.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 GAO87672.1 - 0.012 14.6 0.2 0.29 10.0 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF938 PF06080.7 GAO87672.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ACP_syn_III PF08545.5 GAO87672.1 - 0.013 15.0 0.2 0.047 13.3 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_24 PF13578.1 GAO87672.1 - 0.029 15.1 0.0 0.11 13.3 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 GAO87672.1 - 0.031 13.7 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO87672.1 - 0.034 14.4 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 GAO87672.1 - 0.082 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 GAO87672.1 - 0.1 12.0 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 1 0 Putative methyltransferase DREV PF05219.7 GAO87672.1 - 0.38 9.5 0.0 1 8.2 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase RrnaAD PF00398.15 GAO87672.1 - 0.59 9.1 0.0 1.1 8.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF915 PF06028.6 GAO87672.1 - 0.59 9.1 0.0 1.2 8.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 GAO87673.1 - 8.3e-28 97.1 66.1 8.3e-28 97.1 45.8 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87673.1 - 1.5e-07 30.3 17.9 1.5e-07 30.3 12.4 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter adh_short PF00106.20 GAO87674.1 - 1.9e-13 50.6 0.0 4.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO87674.1 - 1.9e-05 24.3 0.2 3.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 KR domain DUF3237 PF11578.3 GAO87675.1 - 5.1e-24 84.2 0.0 5.8e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF3049 PF11250.3 GAO87675.1 - 0.0052 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3049) YorP PF09629.5 GAO87676.1 - 0.075 13.0 0.0 0.42 10.6 0.0 2.1 1 1 0 1 1 1 0 YorP protein DUF2274 PF10038.4 GAO87676.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) FAD_binding_3 PF01494.14 GAO87677.1 - 5.2e-22 78.3 0.8 1.7e-20 73.4 0.6 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO87677.1 - 3.6e-05 23.6 0.7 0.00013 21.9 0.5 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO87677.1 - 0.0039 16.0 2.4 0.0061 15.4 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO87677.1 - 0.0054 16.6 0.3 0.0096 15.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO87677.1 - 0.0089 15.6 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 GAO87677.1 - 0.011 14.6 0.8 0.043 12.7 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAO87677.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 GAO87677.1 - 0.028 13.3 0.0 0.2 10.5 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 GAO87677.1 - 0.04 12.3 0.3 0.064 11.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 GAO87677.1 - 0.045 12.6 0.2 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAO87677.1 - 0.058 13.4 0.2 0.098 12.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO87677.1 - 0.088 11.8 0.2 9.3 5.1 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAO87677.1 - 0.11 12.9 0.2 0.29 11.5 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 GAO87678.1 - 1.7e-17 63.2 1.4 2.6e-17 62.5 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO87678.1 - 1.3e-10 40.9 0.5 3.3e-10 39.7 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAO87678.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Pyr_redox_3 PF13738.1 GAO87679.1 - 3.6e-22 79.4 0.0 4.6e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO87679.1 - 2.6e-11 42.4 0.0 7.1e-06 24.4 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO87679.1 - 4.4e-07 29.1 0.0 9.9e-06 24.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAO87679.1 - 1.5e-06 28.0 0.0 0.18 11.5 0.0 4.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO87679.1 - 8.9e-05 22.4 0.0 0.0039 17.0 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87679.1 - 0.0036 17.2 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAO87679.1 - 0.0093 14.4 0.0 1.9 6.8 0.0 3.0 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.12 GAO87679.1 - 0.015 14.4 0.1 0.035 13.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family UPF0233 PF06781.7 GAO87679.1 - 0.071 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Lycopene_cycl PF05834.7 GAO87679.1 - 0.1 11.4 0.0 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2834 PF11196.3 GAO87680.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) DUF3311 PF11755.3 GAO87680.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) ketoacyl-synt PF00109.21 GAO87681.1 - 6.6e-68 228.9 0.0 2.2e-67 227.1 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO87681.1 - 1.7e-63 214.8 1.3 3.2e-63 214.0 0.3 1.9 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAO87681.1 - 1e-62 211.9 0.0 1.9e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAO87681.1 - 1.2e-59 200.9 2.6 2.6e-59 199.9 0.9 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAO87681.1 - 8.5e-50 168.9 0.8 8.5e-50 168.9 0.5 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO87681.1 - 4.1e-30 104.0 0.4 1.6e-29 102.1 0.3 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAO87681.1 - 3.2e-06 26.7 0.1 1.1e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 GAO87681.1 - 0.00026 20.0 0.3 0.0006 18.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 GAO87681.1 - 0.00078 19.1 0.6 0.0026 17.5 0.4 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAO87681.1 - 0.0022 18.2 0.0 0.0075 16.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1479 PF07350.7 GAO87682.1 - 4.2e-155 516.3 0.0 5.2e-155 516.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) HAD_2 PF13419.1 GAO87682.1 - 2.7e-18 66.8 0.0 5.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO87682.1 - 5.1e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO87682.1 - 8.4e-07 29.6 0.0 3.8e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO87682.1 - 0.0053 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Death PF00531.17 GAO87682.1 - 0.023 14.4 0.2 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Death domain PhyH PF05721.8 GAO87682.1 - 0.031 14.3 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Hydrolase_6 PF13344.1 GAO87682.1 - 0.17 11.7 0.0 3.3 7.6 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 GAO87683.1 - 2.7e-08 32.9 40.7 2.7e-08 32.9 28.2 4.4 2 2 2 4 4 4 3 Major Facilitator Superfamily NmrA PF05368.8 GAO87684.1 - 5.7e-26 91.2 0.0 6.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO87684.1 - 6.4e-18 65.4 0.2 8.9e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO87684.1 - 2.8e-06 26.9 0.0 0.0011 18.4 0.0 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO87684.1 - 0.00013 21.9 0.5 0.00027 20.8 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAO87684.1 - 0.00046 18.9 0.0 0.00082 18.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAO87684.1 - 0.00083 19.0 0.1 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAO87684.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 GAO87684.1 - 0.055 12.3 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 GAO87684.1 - 0.06 12.2 0.1 0.32 9.8 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 GAO87684.1 - 0.12 12.3 0.1 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GST_C PF00043.20 GAO87685.1 - 2.3e-14 53.1 0.8 3.5e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO87685.1 - 3.3e-10 40.0 0.0 7.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO87685.1 - 4.1e-10 39.7 0.0 8.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO87685.1 - 7.9e-08 32.6 0.8 1.2e-07 32.1 0.5 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO87685.1 - 1.4e-07 31.4 0.1 4.6e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO87685.1 - 6.1e-05 22.8 1.1 0.00012 21.9 0.8 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GlutR_dimer PF00745.15 GAO87685.1 - 0.047 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain RPEL PF02755.10 GAO87685.1 - 0.053 12.8 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 RPEL repeat DUF59 PF01883.14 GAO87685.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF59 DUF3613 PF12266.3 GAO87685.1 - 0.28 10.7 1.7 1.2 8.6 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3613) adh_short PF00106.20 GAO87686.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87686.1 - 2.5e-08 33.9 0.0 3.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87686.1 - 9.9e-08 31.8 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 GAO87687.1 - 5.5e-59 199.2 0.9 6.9e-59 198.9 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO87687.1 - 6.5e-13 49.0 0.0 8.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO87687.1 - 9.7e-05 21.2 0.3 0.00015 20.6 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 GAO87687.1 - 0.0032 16.4 0.1 0.029 13.3 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 GAO87687.1 - 0.08 12.9 0.1 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DXP_reductoisom PF02670.11 GAO87687.1 - 0.089 13.3 0.2 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Abhydrolase_3 PF07859.8 GAO87688.1 - 6.8e-50 169.5 0.0 9.9e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAO87688.1 - 5.2e-10 38.6 0.1 8.8e-10 37.9 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAO87688.1 - 2.1e-05 24.2 0.1 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 GAO87688.1 - 0.00075 18.1 5.4 0.0021 16.7 3.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S9 PF00326.16 GAO87688.1 - 0.0094 15.1 0.0 0.034 13.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family p450 PF00067.17 GAO87689.1 - 2.9e-48 164.5 0.0 3.8e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 GAO87690.1 - 9.9e-39 133.2 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 GAO87690.1 - 0.043 12.6 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.16 GAO87690.1 - 0.051 12.7 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3860 PF12976.2 GAO87690.1 - 0.068 12.9 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) FAD_binding_3 PF01494.14 GAO87691.1 - 2.4e-13 49.9 0.3 5.8e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO87691.1 - 7.3e-09 35.5 1.9 1.7e-08 34.3 1.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAO87691.1 - 5.7e-07 28.9 0.1 8.4e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAO87691.1 - 3.1e-06 26.3 4.1 7.5e-06 25.0 2.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO87691.1 - 6.2e-06 26.2 0.1 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO87691.1 - 7.2e-06 26.3 1.6 9.4e-06 25.9 0.2 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO87691.1 - 7.2e-05 21.8 4.2 0.00016 20.6 3.0 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAO87691.1 - 0.0001 21.3 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 GAO87691.1 - 0.00064 18.6 1.9 0.00097 18.0 1.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 GAO87691.1 - 0.0012 17.9 0.3 0.0026 16.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAO87691.1 - 0.0044 15.5 1.2 0.0066 14.9 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 GAO87691.1 - 0.0047 16.0 0.0 0.015 14.4 0.1 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAO87691.1 - 0.03 14.3 0.3 0.19 11.7 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO87691.1 - 0.042 12.4 0.5 0.24 9.9 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 GAO87691.1 - 0.076 12.7 0.5 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAO87691.1 - 0.094 12.3 0.8 0.16 11.5 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO87691.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_2 PF00891.13 GAO87692.1 - 1.9e-24 86.2 0.0 3.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 GAO87692.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 GAO87692.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PRK PF00485.13 GAO87693.1 - 2.4e-07 30.4 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 GAO87693.1 - 3.7e-06 27.7 0.1 6.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO87693.1 - 7.7e-05 22.9 0.1 0.00032 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO87693.1 - 0.00091 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 GAO87693.1 - 0.023 14.3 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAO87693.1 - 0.024 14.5 0.1 0.65 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAO87693.1 - 0.037 13.1 0.0 0.098 11.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 GAO87693.1 - 0.039 13.6 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.5 GAO87693.1 - 0.053 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 GAO87693.1 - 0.058 12.7 0.1 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.1 GAO87693.1 - 0.062 12.8 0.1 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain LysM PF01476.15 GAO87695.1 - 7e-05 22.6 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 LysM domain G_glu_transpept PF01019.16 GAO87696.1 - 3.9e-143 477.6 0.0 4.6e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RRP7 PF12923.2 GAO87697.1 - 0.085 12.8 3.3 0.2 11.6 2.3 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) ADP_PFK_GK PF04587.10 GAO87697.1 - 0.094 10.9 0.4 0.11 10.6 0.3 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Collagen PF01391.13 GAO87697.1 - 0.11 12.0 6.3 0.22 11.0 4.4 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Glutenin_hmw PF03157.8 GAO87697.1 - 0.9 7.7 36.2 1.6 6.9 25.1 1.4 1 1 0 1 1 1 0 High molecular weight glutenin subunit LEA_3 PF03242.8 GAO87697.1 - 2.3 8.4 7.5 7.7 6.8 5.1 2.0 1 1 0 1 1 1 0 Late embryogenesis abundant protein Rad60-SLD PF11976.3 GAO87698.1 - 1.1e-21 76.2 0.0 2.3e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Trm112p PF03966.11 GAO87699.1 - 9.5e-17 61.1 0.1 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 GAO87699.1 - 0.055 13.7 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain N-SET PF11764.3 GAO87700.1 - 1.6e-50 171.3 0.5 4.5e-50 169.8 0.3 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 GAO87700.1 - 9.4e-24 84.5 0.1 9.4e-24 84.5 0.1 3.1 4 1 0 4 4 4 1 SET domain SET_assoc PF11767.3 GAO87700.1 - 1.2e-20 72.5 0.2 2.5e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SIS PF01380.17 GAO87701.1 - 3.6e-56 188.3 0.0 2.5e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 GAO87701.1 - 3.7e-28 98.2 0.0 2.1e-19 69.4 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAO87701.1 - 7.8e-20 71.1 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAO87701.1 - 1.7e-12 47.1 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAO87701.1 - 2e-08 33.2 0.0 3.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 GAO87701.1 - 0.099 12.3 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 SIS domain DMRL_synthase PF00885.14 GAO87702.1 - 1e-27 96.5 0.0 1.2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 GAO87703.1 - 1.8e-30 105.6 0.5 2.1e-15 56.5 0.0 2.5 2 1 1 3 3 3 2 Proteasome subunit DUF883 PF05957.8 GAO87704.1 - 1.1 9.6 6.4 0.69 10.3 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Iso_dh PF00180.15 GAO87705.1 - 3.3e-83 279.5 0.0 4.1e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Chorion_S16 PF05836.7 GAO87705.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 RhoGAP PF00620.22 GAO87706.1 - 2.5e-42 144.0 0.1 5.2e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain WBS_methylT PF12589.3 GAO87706.1 - 5.7e-16 58.7 1.8 5.7e-16 58.7 1.3 2.7 3 0 0 3 3 2 1 Methyltransferase involved in Williams-Beuren syndrome PH PF00169.24 GAO87706.1 - 1e-10 41.7 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Methyltransf_11 PF08241.7 GAO87706.1 - 1.8e-10 41.1 0.0 4.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87706.1 - 2.4e-07 31.0 0.0 8.7e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PH_11 PF15413.1 GAO87706.1 - 7.3e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Methyltransf_31 PF13847.1 GAO87706.1 - 2.9e-05 23.6 0.0 6.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87706.1 - 0.00014 22.3 0.0 0.00049 20.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87706.1 - 0.00035 20.9 0.0 0.0011 19.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DUF3450 PF11932.3 GAO87706.1 - 0.00057 19.2 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Methyltransf_26 PF13659.1 GAO87706.1 - 0.0012 18.9 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO87706.1 - 0.0029 17.1 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 GAO87706.1 - 0.0031 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dpoe2NT PF12213.3 GAO87706.1 - 0.12 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal MDM31_MDM32 PF08118.6 GAO87707.1 - 2.6e-193 643.0 0.3 2.9e-193 642.8 0.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 GAO87708.1 - 0.0038 16.8 0.4 0.0081 15.7 0.3 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 GAO87709.1 - 1.7e-33 115.5 0.1 3.9e-33 114.3 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome PF00227.21 GAO87710.1 - 5.1e-28 97.6 0.0 6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Lambda_Kil PF06301.6 GAO87710.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein FAA_hydrolase PF01557.13 GAO87711.1 - 5e-61 205.9 0.0 6.5e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 GAO87712.1 - 2.5e-17 62.6 0.0 1e-11 44.5 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family RRM_5 PF13893.1 GAO87714.1 - 9.1e-10 38.2 0.1 1.3e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO87714.1 - 6.9e-09 35.2 0.1 1.6e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO87714.1 - 4.4e-05 23.3 0.0 8.3e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.20 GAO87715.1 - 5.4e-30 103.8 0.0 8.7e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) WD40 PF00400.27 GAO87715.1 - 2.2e-19 68.5 7.9 1.9e-08 33.8 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 GAO87715.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Rax2 PF12768.2 GAO87715.1 - 0.0025 17.0 0.0 0.0095 15.1 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Abhydrolase_6 PF12697.2 GAO87715.1 - 0.0068 16.3 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO87715.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 GAO87715.1 - 0.022 15.0 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 GAO87715.1 - 0.14 11.4 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF4444 PF14563.1 GAO87715.1 - 0.67 9.3 3.3 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) WW PF00397.21 GAO87716.1 - 4.3e-09 36.0 0.6 1.4e-08 34.4 0.4 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 GAO87716.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Fungal_trans_2 PF11951.3 GAO87717.1 - 4.6e-13 48.5 4.7 1.3e-11 43.7 3.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.2 GAO87718.1 - 8.5e-168 558.9 0.2 6.7e-164 546.0 0.0 3.3 2 1 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.17 GAO87718.1 - 9.3e-07 28.4 0.9 2.9 8.2 0.1 7.2 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.2 GAO87718.1 - 0.00052 20.3 3.9 0.02 15.2 0.1 4.7 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAO87718.1 - 0.0065 16.9 9.4 1.3 9.5 0.0 7.6 5 1 1 6 6 6 1 HEAT-like repeat SNF2_N PF00176.18 GAO87719.1 - 3e-55 187.1 0.0 6.2e-55 186.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 GAO87719.1 - 7.5e-08 32.0 10.4 7.5e-08 32.0 7.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAO87719.1 - 7.5e-08 31.9 9.1 1.6e-07 30.8 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO87719.1 - 2e-07 30.5 7.7 4.6e-07 29.4 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO87719.1 - 1.2e-06 28.4 10.6 2.7e-06 27.3 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO87719.1 - 0.00016 21.7 5.8 0.0004 20.4 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAO87719.1 - 0.00033 20.3 8.9 0.00064 19.3 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 GAO87719.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 GAO87719.1 - 0.028 14.3 8.3 0.056 13.3 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cdc6_C PF09079.6 GAO87719.1 - 0.036 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal Prok-RING_4 PF14447.1 GAO87719.1 - 0.065 12.7 4.9 0.15 11.6 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 GAO87719.1 - 0.065 12.9 6.8 0.15 11.7 4.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAO87719.1 - 0.082 12.5 6.3 0.26 10.8 4.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AhpC-TSA PF00578.16 GAO87719.1 - 0.089 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Hormone_3 PF00159.13 GAO87719.1 - 0.32 11.0 2.0 0.52 10.3 0.0 2.5 3 0 0 3 3 2 0 Pancreatic hormone peptide DZR PF12773.2 GAO87719.1 - 0.66 9.8 3.2 1.7 8.5 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon PNGaseA PF12222.3 GAO87720.1 - 2.7e-165 550.4 3.8 3.2e-165 550.1 2.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A PMM PF03332.8 GAO87721.1 - 3.4e-102 340.6 0.0 5.7e-102 339.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF1640 PF07798.6 GAO87721.1 - 1.6e-64 217.1 4.5 1.6e-64 217.1 3.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) TMPIT PF07851.8 GAO87721.1 - 0.072 12.1 0.1 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 TMPIT-like protein DnaJ PF00226.26 GAO87722.1 - 5.2e-31 106.1 4.4 3e-17 62.1 0.1 2.8 2 1 0 2 2 2 2 DnaJ domain Gly-zipper_OmpA PF13436.1 GAO87722.1 - 0.014 15.0 0.2 0.046 13.3 0.1 1.9 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 GAO87722.1 - 0.18 11.8 2.0 0.26 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF456) PRA1 PF03208.14 GAO87723.1 - 4.4e-42 143.0 1.6 5e-42 142.8 1.1 1.0 1 0 0 1 1 1 1 PRA1 family protein Frag1 PF10277.4 GAO87725.1 - 5.5e-42 143.6 16.3 6.4e-42 143.4 11.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Herpes_UL37_2 PF07413.6 GAO87725.1 - 0.056 12.2 0.1 7.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 Epiglycanin_C PF14654.1 GAO87725.1 - 0.15 12.1 1.7 0.44 10.5 1.2 2.0 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Y_phosphatase3 PF13350.1 GAO87726.1 - 6.5e-29 101.2 0.3 9.7e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAO87726.1 - 8.4e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 GAO87726.1 - 1.2e-06 27.9 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAO87726.1 - 0.0063 16.1 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAO87726.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_hydro_35 PF01301.14 GAO87727.1 - 5.5e-81 272.3 4.1 8.3e-81 271.7 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAO87727.1 - 2.1e-58 196.7 4.1 4.5e-58 195.6 2.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAO87727.1 - 6.4e-48 161.6 5.8 3.6e-24 85.1 1.5 3.5 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAO87727.1 - 3.5e-28 96.8 0.2 1e-27 95.3 0.1 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF3812 PF12757.2 GAO87728.1 - 3.6e-40 136.8 12.8 3.6e-40 136.8 8.8 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF3812) LMBR1 PF04791.11 GAO87728.1 - 4.2 5.8 4.8 6.4 5.2 3.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.11 GAO87729.1 - 1.4e-35 122.6 16.9 1.4e-35 122.6 11.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87729.1 - 2.2e-07 29.8 13.2 2.2e-07 29.8 9.2 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.6 GAO87730.1 - 2.3e-12 46.5 10.8 2.3e-12 46.5 7.5 2.4 2 1 0 2 2 2 1 CFEM domain DNA_pol_viral_N PF00242.12 GAO87730.1 - 0.31 10.0 7.1 0.35 9.8 4.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pex14_N PF04695.8 GAO87730.1 - 1.3 9.0 7.9 2.1 8.3 5.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 GAO87730.1 - 5.5 5.1 12.6 6.4 4.9 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Ilm1 PF10311.4 GAO87731.1 - 6.4e-69 230.6 2.3 8.5e-69 230.2 1.6 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Pkinase PF00069.20 GAO87732.1 - 3.9e-67 226.1 0.0 6e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87732.1 - 2.2e-40 138.3 0.0 3.3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Prenyltrans_2 PF13249.1 GAO87732.1 - 2.2e-20 73.1 0.0 1.6e-18 67.1 0.0 3.2 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans PF00432.16 GAO87732.1 - 2.3e-20 71.8 12.1 3.5e-05 23.2 0.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Kinase-like PF14531.1 GAO87732.1 - 3.9e-10 39.1 0.0 3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Prenyltrans_1 PF13243.1 GAO87732.1 - 0.0037 17.2 0.0 0.18 11.8 0.0 2.9 1 1 1 2 2 2 2 Prenyltransferase-like APH PF01636.18 GAO87732.1 - 0.017 14.8 10.5 2.2 7.9 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 GAO87732.1 - 0.019 14.0 1.4 0.027 13.5 0.0 1.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 GAO87733.1 - 3.5e-14 52.2 42.5 8.1e-13 47.8 29.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87733.1 - 5.5e-05 21.9 6.0 5.5e-05 21.9 4.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2811 PF10929.3 GAO87733.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) E1-E2_ATPase PF00122.15 GAO87734.1 - 6e-66 221.7 6.0 6e-66 221.7 4.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO87734.1 - 5.6e-46 156.3 6.2 5.6e-46 156.3 4.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO87734.1 - 1.9e-31 110.1 0.0 4.1e-30 105.7 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO87734.1 - 3.1e-21 75.1 0.0 6.1e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO87734.1 - 2.4e-16 60.4 0.0 7.6e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO87734.1 - 3.6e-07 30.0 2.1 4.6e-06 26.4 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO87734.1 - 1.4e-06 27.6 0.0 4.3e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD_2 PF13419.1 GAO87734.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 GAO87735.1 - 3.9e-115 382.8 2.7 4.8e-115 382.5 1.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 GAO87735.1 - 0.054 13.4 0.4 7.5 6.5 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4085 PF13315.1 GAO87735.1 - 0.062 12.6 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 GAO87735.1 - 0.092 12.7 1.3 14 5.7 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain eIF3_subunit PF08597.5 GAO87736.1 - 3.3e-72 243.0 28.5 3.6e-72 242.8 19.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DMRL_synthase PF00885.14 GAO87736.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase LigB PF02900.13 GAO87736.1 - 0.28 10.1 2.2 4.5 6.1 0.0 2.4 2 1 1 3 3 3 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase MRC1 PF09444.5 GAO87736.1 - 2.4 8.4 24.9 0.27 11.5 13.0 2.2 2 0 0 2 2 2 0 MRC1-like domain ATC_hydrolase PF14196.1 GAO87736.1 - 6.8 7.0 10.2 2.5 8.4 0.0 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase FAM60A PF15396.1 GAO87736.1 - 8.3 6.0 11.2 2.4 7.8 3.7 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Enolase_C PF00113.17 GAO87737.1 - 1.1e-152 507.2 0.1 1.4e-152 506.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 GAO87737.1 - 1.9e-57 192.8 0.2 3.3e-57 192.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 GAO87737.1 - 0.02 13.8 0.3 0.75 8.6 0.0 2.8 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 GAO87737.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 GAO87737.1 - 0.033 14.7 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain AAA PF00004.24 GAO87738.1 - 4.6e-43 146.5 0.0 7.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO87738.1 - 2.3e-07 30.9 0.0 1.6e-05 24.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAO87738.1 - 2.1e-06 27.7 0.0 6.5e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAO87738.1 - 2.2e-06 27.4 0.1 5.5e-05 22.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAO87738.1 - 3.1e-06 26.3 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAO87738.1 - 7e-06 26.2 0.0 0.0013 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAO87738.1 - 0.00029 19.8 0.0 0.00074 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAO87738.1 - 0.00074 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 GAO87738.1 - 0.0016 17.6 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 GAO87738.1 - 0.0023 18.7 0.5 0.0064 17.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 GAO87738.1 - 0.0024 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAO87738.1 - 0.0027 17.5 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO87738.1 - 0.0028 16.4 0.0 0.0052 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 GAO87738.1 - 0.0043 16.5 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAO87738.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAO87738.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 GAO87738.1 - 0.0061 16.8 0.1 0.02 15.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 GAO87738.1 - 0.0067 16.3 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAO87738.1 - 0.0094 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAO87738.1 - 0.011 15.1 0.1 0.061 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 GAO87738.1 - 0.012 15.7 0.0 0.035 14.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 GAO87738.1 - 0.02 14.5 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 GAO87738.1 - 0.024 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 GAO87738.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAO87738.1 - 0.025 13.6 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 GAO87738.1 - 0.031 13.8 0.1 0.18 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAO87738.1 - 0.037 13.7 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 GAO87738.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GAS PF13851.1 GAO87738.1 - 0.04 13.1 0.3 0.083 12.0 0.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Parvo_NS1 PF01057.12 GAO87738.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 GAO87738.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAO87738.1 - 0.073 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 GAO87738.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 GAO87738.1 - 0.091 12.1 0.0 2.9 7.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_23 PF13476.1 GAO87738.1 - 3.3 7.9 5.5 4.9 7.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.15 GAO87739.1 - 3.5e-167 556.6 0.0 4.2e-167 556.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 M20_dimer PF07687.9 GAO87740.1 - 2.7e-20 72.2 0.1 5.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAO87740.1 - 5.1e-20 71.7 0.2 7.3e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 GAO87740.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 PNK3P PF08645.6 GAO87742.1 - 2e-54 183.3 0.0 7.1e-54 181.5 0.0 1.9 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 GAO87742.1 - 5.4e-36 123.5 0.0 3.2e-35 121.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 GAO87742.1 - 3.1e-07 29.8 0.1 0.00068 18.9 0.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 GAO87742.1 - 3.1e-05 23.1 0.0 0.015 14.3 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin AAA_22 PF13401.1 GAO87742.1 - 0.031 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO87742.1 - 0.076 13.3 0.3 16 5.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain Med18 PF09637.5 GAO87743.1 - 6.5e-73 245.3 0.0 7.3e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 GAO87744.1 - 7.7e-43 146.0 0.3 8.7e-43 145.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 GAO87745.1 - 3.4e-90 301.6 3.5 4.7e-90 301.1 2.4 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 GAO87746.1 - 5.2e-13 49.1 0.0 8.2e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3893 PF13032.1 GAO87746.1 - 0.067 13.3 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3893) Pkinase PF00069.20 GAO87747.1 - 5.4e-36 124.0 0.0 6.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87747.1 - 1.9e-14 53.3 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO87747.1 - 0.016 14.9 0.0 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtt106 PF08512.7 GAO87748.1 - 3.1e-27 94.3 0.1 1.4e-26 92.3 0.0 2.0 2 1 1 3 3 3 1 Histone chaperone Rttp106-like DUF779 PF05610.6 GAO87748.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF779) KOW PF00467.24 GAO87749.1 - 9.9e-07 28.2 1.9 1.7e-06 27.5 1.3 1.4 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 GAO87750.1 - 7.5e-56 187.9 0.0 8.7e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO87750.1 - 1.7e-15 57.5 0.0 2.7e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO87750.1 - 5.5e-07 28.9 0.0 9.3e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAO87750.1 - 0.0022 17.2 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAO87750.1 - 0.023 13.8 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 GAO87750.1 - 0.14 11.5 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1712 PF08217.6 GAO87751.1 - 6.4e-17 61.0 0.0 2.9e-13 48.9 0.0 2.5 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 GAO87752.1 - 2.1e-08 33.9 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 GAO87752.1 - 9.5e-05 22.4 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain adh_short PF00106.20 GAO87753.1 - 4e-29 101.6 0.1 5.7e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87753.1 - 1.1e-21 77.7 0.2 1.3e-21 77.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO87753.1 - 9.6e-13 48.1 0.1 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO87753.1 - 7.7e-06 25.5 0.0 2.8e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alg14 PF08660.6 GAO87754.1 - 2.5e-53 180.5 0.0 3.6e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF624 PF04854.9 GAO87754.1 - 0.23 11.3 2.0 3.8 7.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF624 Ima1_N PF09779.4 GAO87755.1 - 2.8e-46 157.2 3.1 6.3e-46 156.1 2.1 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 GAO87755.1 - 0.73 9.7 4.1 8.3 6.3 0.6 2.6 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 GAO87755.1 - 1.4 8.6 4.3 1.4 8.6 1.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 GAO87755.1 - 3.6 7.4 9.1 0.8 9.5 3.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sugar_tr PF00083.19 GAO87756.1 - 1.2e-112 376.7 23.5 1.4e-112 376.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO87756.1 - 1.1e-16 60.4 47.5 3.8e-15 55.4 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.4 GAO87757.1 - 1.3e-133 445.1 0.2 1.6e-133 444.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) PH_10 PF15411.1 GAO87758.1 - 8.7e-24 83.9 0.1 1.6e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 GAO87758.1 - 6.4e-13 48.6 0.0 2.2e-12 46.9 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 GAO87758.1 - 6.4e-08 32.3 5.3 1.3e-07 31.3 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 GAO87758.1 - 1.2e-07 31.6 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 GAO87758.1 - 0.0003 20.4 4.6 0.00052 19.6 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAO87758.1 - 0.002 18.1 4.3 0.0036 17.2 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO87758.1 - 0.0026 17.8 1.2 0.0051 16.8 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger PH PF00169.24 GAO87758.1 - 0.0031 17.6 0.3 0.0073 16.4 0.2 1.6 1 0 0 1 1 1 1 PH domain zf-C3HC4 PF00097.20 GAO87758.1 - 0.0058 16.2 4.7 0.011 15.4 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAO87758.1 - 0.18 11.8 4.4 0.35 10.9 3.0 1.5 1 0 0 1 1 1 0 RING-like domain TMEM171 PF15471.1 GAO87759.1 - 9.6 4.8 9.2 0.55 8.9 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 Fungal_trans_2 PF11951.3 GAO87760.1 - 2.3e-84 283.1 3.7 3e-84 282.8 2.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87760.1 - 2.1e-08 33.9 8.6 3.9e-08 33.0 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_1 PF00536.25 GAO87761.1 - 1.2e-10 41.4 0.1 2.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAO87761.1 - 6.5e-10 38.7 0.1 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 GAO87761.1 - 1.6e-05 25.0 0.4 6.6e-05 23.0 0.1 2.3 2 1 0 2 2 2 1 PH domain Ste50p-SAM PF09235.5 GAO87761.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 GAO87761.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ank_2 PF12796.2 GAO87762.1 - 4.9e-78 257.5 23.7 3.3e-19 68.9 0.4 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87762.1 - 4.3e-70 228.2 13.6 9.6e-10 37.7 0.1 13.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 GAO87762.1 - 1e-53 178.7 14.6 1.4e-12 47.7 0.1 10.9 4 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO87762.1 - 2.2e-52 169.7 7.3 5e-06 26.2 0.1 14.0 14 1 0 14 14 13 9 Ankyrin repeat Ank_5 PF13857.1 GAO87762.1 - 2.4e-45 151.5 14.4 7.6e-08 32.3 0.0 9.8 4 4 3 8 8 8 8 Ankyrin repeats (many copies) NACHT PF05729.7 GAO87762.1 - 2.6e-08 33.6 0.0 1e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAO87762.1 - 9.7e-08 32.2 0.0 3.7e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO87762.1 - 0.00038 20.4 0.1 0.0011 18.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAO87762.1 - 0.0066 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.12 GAO87762.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 GAO87762.1 - 0.025 14.4 0.0 0.089 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAO87762.1 - 0.025 14.7 0.0 0.083 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APG5 PF04106.7 GAO87763.1 - 6.1e-67 224.9 0.0 7.2e-67 224.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 Na_H_Exchanger PF00999.16 GAO87764.1 - 3.1e-34 118.1 39.8 3.8e-26 91.5 18.4 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Abhydrolase_6 PF12697.2 GAO87765.1 - 8.7e-20 71.5 1.2 2.3e-19 70.2 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO87765.1 - 1.3e-11 44.4 0.1 3e-11 43.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO87765.1 - 1.1e-09 38.2 0.2 9.6e-09 35.1 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAO87765.1 - 5.2e-06 25.9 0.0 0.0021 17.3 0.0 3.0 3 0 0 3 3 3 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 GAO87765.1 - 6.4e-06 25.9 0.0 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 GAO87765.1 - 0.025 13.4 1.9 0.034 13.0 0.9 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 GAO87765.1 - 0.061 12.8 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAO87765.1 - 0.2 11.2 1.0 0.68 9.5 0.4 2.0 2 0 0 2 2 2 0 Lipase (class 3) Glyco_hydro_7 PF00840.15 GAO87766.1 - 1.9e-215 715.2 18.7 2.2e-215 715.0 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 WD40 PF00400.27 GAO87767.1 - 0.00014 21.5 1.6 0.024 14.5 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat TFIIF_alpha PF05793.7 GAO87767.1 - 0.22 9.8 4.6 0.4 8.9 3.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fe-ADH PF00465.14 GAO87768.1 - 5.8e-73 245.6 1.4 6.6e-73 245.4 1.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAO87768.1 - 2.9e-15 56.2 0.3 4.1e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Diphthamide_syn PF01866.12 GAO87769.1 - 3e-50 171.2 0.0 8.3e-50 169.7 0.0 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CS PF04969.11 GAO87771.1 - 7e-20 71.3 0.1 1.4e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 CS domain Zn_clus PF00172.13 GAO87772.1 - 1.3e-09 37.7 7.8 2.4e-09 36.9 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO87772.1 - 0.00033 19.3 1.4 0.00051 18.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_12 PF08242.7 GAO87774.1 - 1.8e-13 50.7 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87774.1 - 1.1e-10 41.8 0.0 3.4e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87774.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87774.1 - 7.4e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87774.1 - 4.5e-09 36.0 0.0 6.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87774.1 - 4.9e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO87774.1 - 7.5e-06 25.2 0.0 2.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO87774.1 - 5e-05 23.3 0.0 9.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAO87774.1 - 0.00036 20.2 0.0 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase DUF3419 PF11899.3 GAO87774.1 - 0.00057 18.7 0.0 0.00085 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 GAO87774.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 GAO87774.1 - 0.008 15.1 0.0 1.7 7.5 0.0 2.2 1 1 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.1 GAO87774.1 - 0.046 14.5 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4178 PF13785.1 GAO87774.1 - 0.061 13.3 2.8 6.2 6.8 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4178) HlyIII PF03006.15 GAO87775.1 - 5.3e-57 192.7 21.2 6.5e-57 192.4 14.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 GAO87775.1 - 0.034 13.9 0.8 0.11 12.3 0.6 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FimP PF09766.4 GAO87776.1 - 5.5e-26 91.4 12.6 7e-26 91.1 8.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 GAO87776.1 - 0.00042 20.2 15.8 0.0098 15.8 1.9 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) CwfJ_C_1 PF04677.10 GAO87776.1 - 0.013 15.1 0.8 0.26 10.9 0.1 2.1 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 K-box PF01486.12 GAO87776.1 - 0.042 13.6 1.1 0.042 13.6 0.8 3.0 2 2 1 3 3 3 0 K-box region DUF972 PF06156.8 GAO87776.1 - 0.061 13.6 8.3 1.8 8.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rootletin PF15035.1 GAO87776.1 - 0.3 11.0 14.9 0.58 10.1 2.3 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cortex-I_coil PF09304.5 GAO87776.1 - 0.47 10.5 13.0 2 8.4 2.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF349 PF03993.7 GAO87776.1 - 0.69 10.1 8.4 0.24 11.5 3.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Cob_adeno_trans PF01923.13 GAO87776.1 - 0.8 9.4 7.2 0.46 10.2 0.4 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DinB_2 PF12867.2 GAO87776.1 - 0.81 10.0 6.6 3.4 8.0 1.9 3.0 2 1 0 2 2 2 0 DinB superfamily Flagellin_N PF00669.15 GAO87776.1 - 1 9.1 4.5 0.36 10.6 0.4 1.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region RNase_E_G PF10150.4 GAO87776.1 - 4.2 6.5 8.3 0.86 8.7 1.5 2.0 2 0 0 2 2 2 0 Ribonuclease E/G family APG6 PF04111.7 GAO87776.1 - 4.8 6.1 14.6 2 7.4 1.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 GAO87776.1 - 9.5 5.7 14.7 9.1 5.8 0.2 3.3 2 1 1 3 3 3 0 Septum formation initiator PIG-S PF10510.4 GAO87777.1 - 9.5e-187 621.7 2.0 1.1e-186 621.5 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Med3 PF11593.3 GAO87778.1 - 1.2 8.2 17.4 1.9 7.6 12.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sod_Fe_C PF02777.13 GAO87779.1 - 6.6e-14 51.6 0.0 1.7e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 GAO87780.1 - 8.2e-23 80.8 0.0 1.4e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 GAO87780.1 - 5.5e-08 33.0 0.1 1.3e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.13 GAO87781.1 - 5.4e-20 71.3 0.2 2e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87781.1 - 7.1e-06 25.8 12.4 1.6e-05 24.6 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L44 PF00935.14 GAO87781.1 - 0.94 9.5 9.0 5.6 7.0 6.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 UbiA PF01040.13 GAO87782.1 - 8.6e-35 120.1 23.2 1e-34 119.9 16.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Transp_cyt_pur PF02133.10 GAO87785.1 - 7.1e-16 57.7 27.4 1.2e-15 57.0 19.0 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4516 PF14990.1 GAO87785.1 - 0.13 11.8 0.6 0.38 10.3 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) AMP-binding PF00501.23 GAO87786.1 - 1.6e-67 227.7 0.0 2.3e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO87786.1 - 1.3e-11 45.2 0.1 3e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC2_membrane PF01061.19 GAO87787.1 - 3.4e-36 124.3 20.5 6.3e-36 123.5 14.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAO87787.1 - 7.7e-25 87.7 0.0 1.9e-24 86.5 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 GAO87787.1 - 3e-09 37.2 0.0 2.3e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain hEGF PF12661.2 GAO87787.1 - 1.4e-05 24.8 19.8 0.017 15.1 3.5 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF ABC2_membrane_3 PF12698.2 GAO87787.1 - 4.6e-05 22.6 28.6 4.6e-05 22.6 19.8 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 GAO87787.1 - 0.0019 17.6 0.2 0.14 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAO87787.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO87787.1 - 0.017 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO87787.1 - 0.018 15.1 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAO87787.1 - 0.029 13.4 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAO87787.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAO87787.1 - 0.047 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 GAO87787.1 - 0.054 13.8 0.2 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAO87787.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 GAO87787.1 - 0.1 13.4 0.0 0.21 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAO87787.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAO87787.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 GAO87787.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAO87787.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.8 GAO87787.1 - 2.1 8.5 33.2 0.047 13.8 6.2 4.2 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.19 GAO87787.1 - 5.5 6.9 29.0 0.76 9.7 4.7 3.4 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Cornichon PF03311.9 GAO87788.1 - 2.3e-53 179.7 12.0 2.6e-53 179.5 8.4 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 GAO87788.1 - 0.9 9.1 4.3 0.12 12.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Peptidase_M50 PF02163.17 GAO87788.1 - 1.7 7.5 5.1 2.2 7.1 3.6 1.2 1 0 0 1 1 1 0 Peptidase family M50 WD40 PF00400.27 GAO87789.1 - 1.2e-37 126.4 6.9 1.2e-09 37.6 0.0 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 GAO87789.1 - 0.0024 16.0 0.1 0.04 12.0 0.0 2.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 GAO87789.1 - 0.0047 16.4 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 GAO87789.1 - 0.0048 16.6 0.2 0.59 9.8 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAO87789.1 - 0.012 13.9 0.0 0.027 12.7 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain EF-hand_1 PF00036.27 GAO87790.1 - 9.3e-14 49.6 3.0 1.6e-06 27.0 0.2 3.4 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 GAO87790.1 - 1.2e-11 43.9 4.8 2.3e-11 43.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 GAO87790.1 - 1.5e-10 40.0 2.5 0.00012 21.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAO87790.1 - 2.9e-10 40.1 5.5 3.6e-10 39.8 1.7 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.1 GAO87790.1 - 1.9e-08 33.7 5.2 0.0018 17.8 0.2 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 GAO87790.1 - 7.7e-05 21.8 5.3 0.043 13.1 0.2 3.3 3 0 0 3 3 3 2 EF hand 53-BP1_Tudor PF09038.5 GAO87790.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor MFS_1 PF07690.11 GAO87791.1 - 3.3e-35 121.4 58.4 3.3e-35 121.4 40.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87791.1 - 3.7e-10 38.9 8.0 3.7e-10 38.9 5.6 3.3 4 0 0 4 4 4 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 GAO87792.1 - 1.2e-43 149.0 0.0 1.6e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAO87792.1 - 0.00039 20.2 4.5 0.00039 20.2 3.1 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 GAO87792.1 - 0.36 10.5 3.8 0.86 9.3 2.7 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 GAO87793.1 - 1.2e-15 57.4 0.0 2.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAO87793.1 - 2.1e-05 24.8 0.0 0.00021 21.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO87793.1 - 0.0016 18.4 0.2 0.0044 17.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO87793.1 - 0.0033 16.3 0.1 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO87793.1 - 0.0047 15.8 0.1 0.012 14.4 0.0 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAO87793.1 - 0.0072 14.8 0.1 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAO87793.1 - 0.0074 15.4 4.9 0.074 12.1 1.2 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO87793.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO87793.1 - 0.055 12.2 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Ribosomal_S8 PF00410.14 GAO87795.1 - 6.8e-24 84.1 0.0 1.1e-23 83.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 GAO87798.1 - 1.9e-97 326.3 0.0 1.1e-96 323.7 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.5 GAO87799.1 - 6.9e-29 99.5 0.1 1.4e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cnd1_N PF12922.2 GAO87799.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term AAA_13 PF13166.1 GAO87800.1 - 0.067 11.6 27.2 0.024 13.1 0.7 3.1 2 1 1 3 3 3 0 AAA domain DUF1796 PF08795.5 GAO87800.1 - 0.11 12.0 2.5 0.28 10.7 1.3 2.0 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Shugoshin_N PF07558.6 GAO87800.1 - 0.25 11.1 2.5 18 5.1 0.2 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.7 GAO87800.1 - 0.45 10.3 8.8 0.26 11.0 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 GAO87800.1 - 0.56 9.3 20.0 0.4 9.8 3.1 3.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein GAS PF13851.1 GAO87800.1 - 2.1 7.4 36.9 1.1 8.3 10.1 4.4 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Spc42p PF11544.3 GAO87800.1 - 4.6 7.2 12.1 1.6 8.7 0.2 3.9 2 1 1 3 3 3 0 Spindle pole body component Spc42p Baculo_PEP_C PF04513.7 GAO87800.1 - 5.1 6.9 8.0 5.5 6.8 2.7 3.1 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 GAO87800.1 - 6.1 6.3 49.2 0.09 12.3 4.7 4.0 3 1 0 4 4 4 0 IncA protein DUF3506 PF12014.3 GAO87801.1 - 9.7e-52 174.3 0.0 1.5e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 GAO87801.1 - 2.3e-11 43.2 0.5 5.9e-11 41.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO87801.1 - 3.6e-05 23.2 0.0 7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 GAO87801.1 - 0.044 14.1 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.5 GAO87801.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain PK PF00224.16 GAO87802.1 - 3.8e-176 584.8 2.8 4.7e-176 584.5 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAO87802.1 - 1e-32 112.0 0.0 3.2e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAO87802.1 - 4.9e-05 22.3 0.8 0.00013 20.9 0.3 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 GAO87802.1 - 0.0019 17.1 0.1 0.037 12.9 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PIP5K PF01504.13 GAO87803.1 - 3.1e-59 200.1 0.0 9.7e-59 198.5 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 GAO87803.1 - 8.1e-28 97.2 0.0 1.5e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 GAO87803.1 - 2.9e-14 52.6 4.7 2.9e-14 52.6 3.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger TPP1 PF10341.4 GAO87804.1 - 0.00079 19.3 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD TPR_6 PF13174.1 GAO87804.1 - 0.041 14.3 1.4 1 9.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SUR7 PF06687.7 GAO87805.1 - 2.1e-56 190.8 13.8 2.5e-56 190.5 9.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.6 GAO87805.1 - 0.0039 16.2 2.3 0.0039 16.2 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF973) Shisa PF13908.1 GAO87805.1 - 0.038 14.1 8.1 0.087 12.9 0.0 3.1 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF4191 PF13829.1 GAO87805.1 - 0.29 10.2 0.9 0.56 9.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Cellulase PF00150.13 GAO87806.1 - 2.7e-58 197.3 2.4 3.6e-58 197.0 1.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.27 GAO87807.1 - 2.4e-23 81.0 22.3 3.6e-10 39.3 0.1 10.4 10 2 0 10 10 10 5 WD domain, G-beta repeat XPG_N PF00752.12 GAO87808.1 - 4.4e-35 119.9 0.0 1e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAO87808.1 - 8.4e-25 86.6 0.0 2.3e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 GAO87808.1 - 3.7e-05 22.9 1.6 3.7e-05 22.9 1.1 3.2 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 GAO87808.1 - 0.0002 21.5 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Pil1 PF13805.1 GAO87809.1 - 3.5e-152 505.1 0.3 4.5e-152 504.8 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 GAO87809.1 - 0.085 12.1 3.5 0.34 10.2 2.4 1.9 1 1 0 1 1 1 0 FAM92 protein bZIP_2 PF07716.10 GAO87810.1 - 1.2e-11 44.1 16.2 1.2e-11 44.1 11.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 GAO87810.1 - 0.00023 21.0 15.0 0.00023 21.0 10.4 2.4 3 1 0 3 3 3 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 GAO87810.1 - 0.00041 20.1 0.6 0.00093 18.9 0.1 1.8 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 GAO87810.1 - 0.012 15.9 1.2 0.025 14.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3552 PF12072.3 GAO87810.1 - 0.1 11.7 10.6 0.16 11.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1151 PF06625.6 GAO87810.1 - 0.64 9.7 8.0 1.3 8.7 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Cpn60_TCP1 PF00118.19 GAO87811.1 - 2.8e-150 501.1 2.4 3.2e-150 500.9 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 GAO87811.1 - 0.088 12.7 2.6 8.1 6.3 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Resolvase PF00239.16 GAO87811.1 - 0.1 12.4 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain Chromo PF00385.19 GAO87812.1 - 5.8e-10 38.6 1.9 8.9e-10 38.1 0.0 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 GAO87812.1 - 0.00076 19.2 1.2 0.55 10.1 0.1 3.0 2 1 1 3 3 3 2 Chromo shadow domain CENP-B_dimeris PF09026.5 GAO87812.1 - 0.87 9.8 7.5 1.8 8.8 5.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 GAO87812.1 - 4.4 7.6 8.8 0.68 10.2 1.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rap1_C PF11626.3 GAO87813.1 - 4.7e-26 90.5 0.0 9e-26 89.5 0.0 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 GAO87813.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Atx10homo_assoc PF09759.4 GAO87814.1 - 1.8e-32 111.1 0.3 8.2e-32 108.9 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF2501 PF10696.4 GAO87814.1 - 0.053 13.5 0.7 0.17 11.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2501) zf-RING_2 PF13639.1 GAO87815.1 - 9.2e-10 38.1 1.9 1.6e-09 37.4 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO87815.1 - 5.9e-07 29.5 0.4 1.1e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAO87815.1 - 1.5e-05 24.7 0.2 2.2e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 GAO87815.1 - 0.00073 19.5 1.3 0.0017 18.3 0.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 GAO87815.1 - 0.014 15.3 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-C3HC4 PF00097.20 GAO87815.1 - 0.034 13.8 0.6 0.087 12.4 0.4 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO87815.1 - 0.052 13.2 2.1 0.51 10.0 1.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 GAO87816.1 - 2.9e-08 33.5 0.0 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 GAO87816.1 - 8.4e-05 22.6 0.0 0.0072 16.4 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain PGG PF13962.1 GAO87817.1 - 0.21 11.2 7.0 1.1 8.9 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function TMEM192 PF14802.1 GAO87817.1 - 0.8 8.5 6.1 0.077 11.8 0.8 1.7 1 1 1 2 2 2 0 TMEM192 family NTP_transferase PF00483.18 GAO87818.1 - 5.8e-30 104.3 0.0 7.3e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 GAO87818.1 - 3.7e-10 38.8 7.4 1.7e-06 27.2 0.2 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAO87818.1 - 2.2e-08 34.3 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 GAO87818.1 - 0.0021 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 GAO87818.1 - 0.38 10.3 2.5 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 GAO87819.1 - 4.4e-26 91.6 0.0 1e-25 90.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAO87819.1 - 9.1e-20 70.6 0.0 6e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 GAO87819.1 - 6.3e-05 22.9 0.0 0.0024 17.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 GAO87819.1 - 0.00049 19.9 0.5 0.00049 19.9 0.4 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 GAO87819.1 - 0.0047 17.4 0.1 0.013 16.0 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein IIGP PF05049.8 GAO87819.1 - 0.015 14.1 0.4 1.7 7.3 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) tRNA-synt_2 PF00152.15 GAO87820.1 - 2.4e-90 302.6 0.2 4.3e-90 301.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAO87820.1 - 1.1e-13 50.8 0.1 2.5e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAO87820.1 - 1.3e-05 24.4 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UCR_Fe-S_N PF10399.4 GAO87820.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3549 PF12069.3 GAO87822.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Cas_Csa5 PF09702.5 GAO87822.1 - 0.13 12.3 0.1 3.3 7.8 0.0 2.3 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) COX15-CtaA PF02628.10 GAO87823.1 - 4.1e-99 331.2 5.3 5.2e-99 330.9 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Rsm1 PF08600.5 GAO87824.1 - 2.6e-34 116.9 0.1 2.6e-34 116.9 0.0 2.0 2 0 0 2 2 2 1 Rsm1-like zf-C3HC PF07967.8 GAO87824.1 - 4e-28 97.8 0.1 7.9e-23 80.6 0.0 3.5 2 2 0 2 2 2 2 C3HC zinc finger-like Pox_MCEL PF03291.11 GAO87825.1 - 3.5e-60 203.6 0.0 3.1e-47 161.0 0.0 3.8 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 GAO87825.1 - 8.2e-08 32.6 0.0 3.4e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO87825.1 - 3.6e-06 27.3 0.0 0.027 14.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87825.1 - 3.3e-05 23.5 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87825.1 - 4.4e-05 24.0 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87825.1 - 6.9e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAO87825.1 - 0.0074 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.1 GAO87825.1 - 0.014 15.7 0.0 0.1 12.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain zf-Nse PF11789.3 GAO87826.1 - 8.5e-24 82.8 0.8 1.4e-23 82.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 GAO87826.1 - 0.00018 21.2 0.2 0.0003 20.5 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 GAO87826.1 - 0.014 15.0 0.4 0.033 13.9 0.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 GAO87826.1 - 0.017 14.5 1.6 0.15 11.6 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger U-box PF04564.10 GAO87826.1 - 0.17 11.8 0.9 1.7 8.6 0.1 2.5 2 1 0 2 2 2 0 U-box domain Ribosomal_60s PF00428.14 GAO87826.1 - 1.3 9.4 24.9 0.1 13.0 3.4 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein AF1Q PF15017.1 GAO87826.1 - 4.2 7.3 9.7 3.5 7.6 1.6 3.2 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator Mito_carr PF00153.22 GAO87827.1 - 1.4e-56 188.1 2.8 1.1e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEPCK_ATP PF01293.15 GAO87828.1 - 2.6e-216 718.6 0.0 3.2e-216 718.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 GAO87828.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 GAO87828.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO87828.1 - 0.17 12.2 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PEX11 PF05648.9 GAO87829.1 - 2.6e-76 255.8 0.4 5.3e-76 254.7 0.2 1.6 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Na_H_Exchanger PF00999.16 GAO87829.1 - 1.1e-35 122.9 9.2 1.6e-35 122.3 6.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAO87829.1 - 0.017 15.0 0.4 0.062 13.2 0.2 1.9 1 0 0 1 1 1 0 YrhC-like protein Sugar_tr PF00083.19 GAO87830.1 - 1.1e-30 106.6 28.2 5.8e-21 74.5 6.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO87830.1 - 8.5e-19 67.4 37.0 1.2e-13 50.5 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN7 PF10602.4 GAO87831.1 - 2.7e-54 183.2 0.6 4.4e-54 182.5 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAO87831.1 - 4.8e-15 55.7 0.0 1.3e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 GAO87831.1 - 0.044 13.5 0.3 0.35 10.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 GAO87832.1 - 2.1e-39 135.5 0.0 2.9e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Copper-fist PF00649.13 GAO87833.1 - 6.3e-22 76.4 2.9 6.3e-22 76.4 2.0 2.8 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.13 GAO87834.1 - 2.1e-10 40.3 9.1 3.4e-10 39.6 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2463 PF09591.5 GAO87837.1 - 0.0085 15.7 0.3 0.0085 15.7 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2463) SelR PF01641.13 GAO87838.1 - 2.6e-46 156.3 0.1 4.9e-46 155.4 0.1 1.4 1 0 0 1 1 1 1 SelR domain ArfGap PF01412.13 GAO87838.1 - 1.2e-40 137.9 1.6 2.8e-40 136.7 1.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1771 PF08590.5 GAO87839.1 - 5e-16 58.4 7.5 1.1e-15 57.3 5.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAO87839.1 - 5.6e-12 45.6 0.2 1.2e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 GAO87839.1 - 5.8e-07 28.8 0.0 1.6e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 GAO87839.1 - 0.004 16.9 0.0 0.061 13.1 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain GPI-anchored PF10342.4 GAO87841.1 - 1.6e-18 66.9 2.4 1.6e-18 66.9 1.7 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.12 GAO87841.1 - 1.5 8.6 13.3 1.3 8.7 7.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Miro PF08477.8 GAO87842.1 - 2.2e-37 128.1 0.0 2e-18 66.9 0.0 3.6 5 0 0 5 5 2 2 Miro-like protein EF_assoc_2 PF08356.7 GAO87842.1 - 7.7e-34 115.3 0.0 1.4e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 GAO87842.1 - 5.2e-31 105.7 0.1 1e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 GAO87842.1 - 1.4e-25 89.5 0.0 4.6e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Ras family WD40 PF00400.27 GAO87842.1 - 8.5e-17 60.3 12.2 3.5e-06 26.6 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat MMR_HSR1 PF01926.18 GAO87842.1 - 5.1e-09 36.0 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAO87842.1 - 0.00014 21.3 0.2 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_1 PF00036.27 GAO87842.1 - 0.00018 20.5 1.9 0.11 11.8 0.2 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 GAO87842.1 - 0.00023 21.2 3.5 0.24 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 GAO87842.1 - 0.00026 20.9 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_7 PF13499.1 GAO87842.1 - 0.00033 20.7 0.2 0.11 12.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.1 GAO87842.1 - 0.00042 20.4 0.3 2.5 8.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain IKI3 PF04762.7 GAO87842.1 - 0.00084 17.2 0.0 0.0015 16.4 0.0 1.4 1 1 0 1 1 1 1 IKI3 family EF-hand_8 PF13833.1 GAO87842.1 - 0.0015 18.1 1.5 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAO87842.1 - 0.0019 17.9 2.1 0.18 11.7 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain Viral_helicase1 PF01443.13 GAO87842.1 - 0.0031 17.0 0.2 0.034 13.6 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 GAO87842.1 - 0.0033 17.2 0.2 0.85 9.4 0.1 2.9 2 1 0 2 2 2 1 Dynamin family Cytochrom_D1 PF02239.11 GAO87842.1 - 0.0058 14.9 0.0 0.012 13.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain FtsK_SpoIIIE PF01580.13 GAO87842.1 - 0.0082 15.6 0.1 2.1 7.7 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 GAO87842.1 - 0.0089 15.7 0.1 0.48 10.1 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAO87842.1 - 0.01 15.6 0.1 4.7 7.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 GAO87842.1 - 0.012 14.9 0.0 5.5 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 GAO87842.1 - 0.02 14.3 0.1 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain eIF2A PF08662.6 GAO87842.1 - 0.024 14.3 0.0 0.14 11.8 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A RNA_helicase PF00910.17 GAO87842.1 - 0.026 14.6 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 GAO87842.1 - 0.028 13.8 0.0 2.9 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_24 PF13479.1 GAO87842.1 - 0.044 13.3 0.2 0.34 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAO87842.1 - 0.047 13.9 0.0 19 5.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 GAO87842.1 - 0.067 12.8 0.2 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 GAO87842.1 - 0.11 11.2 0.5 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 GAO87842.1 - 0.13 13.1 0.0 37 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAO87842.1 - 0.18 11.5 0.5 49 3.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAO87842.1 - 0.19 12.0 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAO87842.1 - 0.27 10.1 0.2 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_5 PF13202.1 GAO87842.1 - 0.93 8.9 4.0 5.4 6.5 0.3 2.6 2 0 0 2 2 2 0 EF hand ATP_bind_1 PF03029.12 GAO87842.1 - 1.2 8.6 2.2 38 3.6 0.0 3.3 3 1 0 4 4 3 0 Conserved hypothetical ATP binding protein cobW PF02492.14 GAO87842.1 - 1.8 7.9 2.7 7.9 5.8 0.0 3.2 4 1 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF500 PF04366.7 GAO87843.1 - 1.3e-43 147.4 0.2 2.3e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Zds_C PF08632.5 GAO87843.1 - 1.7e-31 107.3 0.9 3e-31 106.5 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SH3_1 PF00018.23 GAO87843.1 - 2.6e-14 52.3 0.1 1e-13 50.4 0.1 2.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAO87843.1 - 1.3e-08 34.1 0.0 3.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAO87843.1 - 1.3e-07 31.1 0.1 3e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Rootletin PF15035.1 GAO87844.1 - 0.12 12.3 0.2 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SNARE PF05739.14 GAO87844.1 - 0.13 11.9 0.1 0.37 10.4 0.0 1.7 1 1 0 1 1 1 0 SNARE domain Arrestin_C PF02752.17 GAO87845.1 - 3.9e-19 69.0 0.0 1.1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAO87845.1 - 1.2e-16 60.8 0.0 2.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 GAO87845.1 - 0.0078 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 GAO87846.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 PH domain CAP_N PF01213.14 GAO87846.1 - 0.097 11.9 0.1 0.097 11.9 0.0 2.5 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BID PF06393.6 GAO87846.1 - 0.11 11.8 0.7 0.2 11.0 0.5 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) IZUMO PF15005.1 GAO87846.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion Acetyltransf_3 PF13302.1 GAO87847.1 - 1.9e-15 57.2 0.0 3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO87847.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 GAO87847.1 - 2.3e-05 24.2 0.0 7.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO87847.1 - 0.0025 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO87847.1 - 0.0034 17.5 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO87847.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 GAO87847.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ig_2 PF13895.1 GAO87848.1 - 0.045 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Abhydrolase_3 PF07859.8 GAO87849.1 - 2.8e-06 27.0 1.2 0.00014 21.4 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAO87849.1 - 0.015 14.7 0.1 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAO87849.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO87849.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 GAO87849.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_C2 PF00648.16 GAO87850.1 - 3e-57 193.8 1.4 1.3e-37 129.4 0.1 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease SOBP PF15279.1 GAO87850.1 - 0.23 11.7 3.6 0.44 10.8 2.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.20 GAO87851.1 - 2.8e-71 239.7 0.0 3.5e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87851.1 - 4e-31 108.0 0.0 5.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87851.1 - 0.0025 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO87851.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO87851.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 GAO87851.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 GAO87852.1 - 3.3e-30 105.3 0.0 1e-29 103.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAO87852.1 - 0.006 17.0 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 GAO87853.1 - 7.1e-98 328.3 0.0 8.3e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.19 GAO87855.1 - 5.4e-89 296.8 64.7 1.5e-49 168.0 16.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO87855.1 - 8.8e-37 124.9 2.2 5.8e-30 103.0 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 GAO87855.1 - 1.2e-35 122.7 0.0 5.7e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAO87855.1 - 7.2e-13 48.2 39.7 4.3e-07 29.2 12.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 GAO87855.1 - 3.6e-07 29.7 0.0 0.00023 20.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 GAO87855.1 - 1.6e-06 28.0 0.0 8.9e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_17 PF13207.1 GAO87855.1 - 1.3e-05 26.0 0.0 0.0068 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 GAO87855.1 - 2.1e-05 24.6 0.2 0.039 13.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 GAO87855.1 - 3.4e-05 23.3 0.1 0.0054 16.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 GAO87855.1 - 5.4e-05 22.7 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAO87855.1 - 9e-05 21.7 0.0 0.0003 20.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAO87855.1 - 0.00062 19.9 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO87855.1 - 0.00075 19.5 0.1 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAO87855.1 - 0.0019 17.7 0.4 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 GAO87855.1 - 0.0032 17.4 0.4 0.0032 17.4 0.2 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 GAO87855.1 - 0.0064 16.3 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO87855.1 - 0.0078 15.9 1.0 0.43 10.3 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 GAO87855.1 - 0.0099 16.2 0.2 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAO87855.1 - 0.011 15.3 0.9 0.1 12.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAO87855.1 - 0.011 15.2 0.2 0.066 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAO87855.1 - 0.014 14.8 0.9 2.7 7.3 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 GAO87855.1 - 0.015 15.6 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAO87855.1 - 0.018 14.7 0.6 0.29 10.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 GAO87855.1 - 0.027 14.4 0.8 0.36 10.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 GAO87855.1 - 0.12 12.6 0.1 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1040 PF06288.8 GAO87855.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) T2SE PF00437.15 GAO87855.1 - 0.15 10.9 0.1 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 GAO87855.1 - 0.29 9.6 0.5 1.1 7.8 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 GAO87855.1 - 0.34 10.4 1.7 0.94 8.9 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.17 GAO87856.1 - 1.2e-17 63.2 0.0 1.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO87856.1 - 6.9e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO87856.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAO87856.1 - 0.042 13.3 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 GAO87857.1 - 1.1e-133 444.9 0.0 1.3e-133 444.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAO87857.1 - 6.8e-53 178.8 0.0 9.8e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAO87857.1 - 0.04 13.9 0.1 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAO87857.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AD PF09793.4 GAO87858.1 - 5.9e-28 96.5 0.0 9.7e-28 95.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Glyco_hydro_15 PF00723.16 GAO87859.1 - 4.8e-50 170.4 0.0 7.7e-48 163.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 YfiO PF13525.1 GAO87859.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein INSIG PF07281.7 GAO87859.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) TPT PF03151.11 GAO87860.1 - 1.8e-32 112.1 11.7 1.8e-32 112.1 8.1 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAO87860.1 - 0.00068 18.6 21.6 0.00068 18.6 15.0 1.9 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 GAO87860.1 - 0.002 18.1 34.8 0.0091 16.0 8.5 3.1 2 2 0 2 2 2 2 EamA-like transporter family REV PF00424.13 GAO87860.1 - 0.056 13.3 5.3 0.12 12.3 3.7 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) CDC45 PF02724.9 GAO87860.1 - 7 4.5 7.3 13 3.6 5.1 1.3 1 0 0 1 1 1 0 CDC45-like protein AP_endonuc_2 PF01261.19 GAO87861.1 - 2.9e-25 88.8 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 GAO87862.1 - 1.3e-43 147.7 0.1 2.4e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 GAO87862.1 - 2.1e-12 46.7 0.0 9.5e-12 44.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 GAO87862.1 - 0.00064 19.5 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 GAO87862.1 - 0.017 14.1 0.0 0.073 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.17 GAO87864.1 - 4e-43 147.6 0.0 5.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C15 PF01470.12 GAO87865.1 - 3.4e-14 53.1 0.1 5.1e-06 26.4 0.0 3.1 3 0 0 3 3 3 3 Pyroglutamyl peptidase MOSC_N PF03476.11 GAO87866.1 - 6.6e-23 80.7 0.0 1.1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAO87866.1 - 3.3e-21 75.1 0.0 4.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain DNA_pol_phi PF04931.8 GAO87867.1 - 1.1e-65 221.9 25.6 3.2e-65 220.3 17.7 1.8 1 1 0 1 1 1 1 DNA polymerase phi SGT1 PF07093.6 GAO87867.1 - 0.012 14.0 23.3 0.02 13.3 16.1 1.4 1 0 0 1 1 1 0 SGT1 protein SDA1 PF05285.7 GAO87867.1 - 0.21 10.8 27.6 0.5 9.5 19.1 1.6 1 0 0 1 1 1 0 SDA1 Rhodanese PF00581.15 GAO87868.1 - 1.9e-12 47.5 0.0 4.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Sld5 PF05916.6 GAO87869.1 - 1.1e-11 44.9 0.1 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Cullin PF00888.17 GAO87870.1 - 9e-131 437.2 9.2 1.1e-130 436.9 6.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAO87870.1 - 6.1e-28 96.4 0.1 2.2e-27 94.6 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.15 GAO87870.1 - 0.083 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator zf-DNL PF05180.7 GAO87871.1 - 1.2e-29 101.8 0.5 1.8e-29 101.2 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 GAO87871.1 - 0.016 14.7 0.2 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.8 GAO87871.1 - 0.038 13.6 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like E7 PF00527.13 GAO87871.1 - 0.039 14.1 0.8 0.081 13.0 0.1 1.9 2 0 0 2 2 2 0 E7 protein, Early protein DRIM PF07539.7 GAO87872.1 - 4.1e-48 162.3 0.0 1.3e-47 160.7 0.0 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 GAO87872.1 - 1.9e-06 27.4 8.7 0.33 11.1 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 GAO87872.1 - 2.3 8.8 16.2 40 4.8 0.0 8.4 9 0 0 9 9 9 0 HEAT-like repeat CwfJ_C_2 PF04676.9 GAO87873.1 - 3.5e-25 88.3 0.1 6e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 GAO87873.1 - 7.2e-25 86.9 0.0 1.2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Lamp PF01299.12 GAO87874.1 - 0.0025 17.0 0.0 0.0025 17.0 0.0 2.1 2 1 1 3 3 3 1 Lysosome-associated membrane glycoprotein (Lamp) LRR19-TM PF15176.1 GAO87874.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain OppC_N PF12911.2 GAO87874.1 - 0.77 9.1 2.5 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RCR PF12273.3 GAO87875.1 - 1.1e-27 97.1 10.9 1.4e-27 96.7 7.6 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Flu_M2 PF00599.12 GAO87875.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Adeno_E3_CR2 PF02439.10 GAO87875.1 - 0.03 13.8 1.3 0.049 13.1 0.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.1 GAO87875.1 - 0.038 13.2 1.3 0.051 12.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Rhabdo_glycop PF00974.13 GAO87875.1 - 0.068 11.3 0.1 0.089 11.0 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF3382 PF11862.3 GAO87875.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Arf PF00025.16 GAO87876.1 - 2.8e-43 147.1 0.0 3.3e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAO87876.1 - 3.3e-19 68.8 0.0 3.8e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO87876.1 - 5.1e-10 39.8 0.0 8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAO87876.1 - 7e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAO87876.1 - 1.2e-06 27.8 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAO87876.1 - 1.6e-05 24.2 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAO87876.1 - 2.8e-05 23.6 0.0 0.00023 20.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 GAO87876.1 - 9.5e-05 21.2 0.0 0.00025 19.8 0.0 1.6 2 1 1 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 GAO87876.1 - 0.00077 19.3 0.0 0.016 15.0 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 GAO87876.1 - 0.014 14.7 0.2 0.11 11.7 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_pol_Rpb2_6 PF00562.23 GAO87877.1 - 3.1e-116 388.3 0.0 4e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAO87877.1 - 8e-33 113.0 0.0 1.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAO87877.1 - 2.3e-26 92.4 0.0 4.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 GAO87877.1 - 3.3e-25 87.8 0.1 8.2e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 GAO87877.1 - 5.7e-24 83.6 0.0 1.4e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 GAO87877.1 - 9.4e-15 54.6 0.1 3.4e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 GAO87877.1 - 0.00084 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Proteasome PF00227.21 GAO87878.1 - 6.9e-44 149.4 0.3 5.4e-34 117.1 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit Pil1 PF13805.1 GAO87879.1 - 3e-88 295.5 5.0 4e-88 295.1 3.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FHIPEP PF00771.15 GAO87879.1 - 0.0021 16.5 0.1 0.0029 16.0 0.1 1.1 1 0 0 1 1 1 1 FHIPEP family V_ATPase_I PF01496.14 GAO87879.1 - 0.009 13.9 0.9 0.013 13.4 0.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF812 PF05667.6 GAO87879.1 - 0.023 13.2 5.1 0.036 12.5 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 GAO87879.1 - 0.036 13.0 2.0 0.07 12.1 1.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Spectrin PF00435.16 GAO87879.1 - 0.11 12.8 3.8 0.61 10.3 0.7 2.6 2 0 0 2 2 2 0 Spectrin repeat LMBR1 PF04791.11 GAO87879.1 - 0.24 9.9 0.8 0.29 9.6 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.4 GAO87879.1 - 0.48 9.3 5.2 0.67 8.8 3.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 GAO87879.1 - 0.66 9.5 5.7 1.3 8.5 3.9 1.4 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 GAO87879.1 - 1.8 8.3 7.8 2.3 8.0 2.8 2.6 2 1 0 2 2 2 0 Tropomyosin like NTPase_P4 PF11602.3 GAO87880.1 - 0.057 12.4 0.6 0.057 12.3 0.4 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 SWI-SNF_Ssr4 PF08549.5 GAO87881.1 - 0 1266.3 14.2 0 1266.2 9.8 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Pox_RNA_Pol_19 PF05320.7 GAO87881.1 - 0.14 11.9 0.1 0.38 10.4 0.1 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit MFS_1 PF07690.11 GAO87882.1 - 5e-37 127.4 28.6 5e-37 127.4 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ppx-GppA PF02541.11 GAO87883.1 - 7e-46 156.6 0.0 1e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 GAO87883.1 - 0.0051 15.3 0.0 0.0085 14.6 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Thi4 PF01946.12 GAO87884.1 - 1e-101 338.8 0.0 1.2e-101 338.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAO87884.1 - 6.6e-09 35.1 0.3 3.7e-08 32.6 0.5 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO87884.1 - 5.7e-06 26.2 0.7 6.5e-05 22.8 0.1 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAO87884.1 - 1.2e-05 24.3 0.5 3.7e-05 22.8 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO87884.1 - 0.00022 21.0 0.8 0.00068 19.4 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO87884.1 - 0.00084 19.4 0.1 0.0013 18.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO87884.1 - 0.0012 17.7 1.1 0.027 13.3 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO87884.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO87884.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO87884.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 GAO87884.1 - 0.097 11.2 0.2 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 GAO87884.1 - 0.17 10.2 0.5 0.28 9.5 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.18 GAO87885.1 - 1.1e-16 61.4 0.1 1.6e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 GAO87886.1 - 7.7e-61 199.9 13.3 4.7e-13 48.4 0.3 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 GAO87886.1 - 1.1e-08 35.0 0.2 0.01 15.5 0.0 3.2 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAO87886.1 - 1.5e-08 33.2 1.8 0.093 10.8 0.0 5.0 2 2 3 5 5 5 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 GAO87886.1 - 0.044 12.0 0.0 0.11 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 GAO87886.1 - 0.2 9.4 0.0 0.33 8.7 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Glyco_hydro_cc PF11790.3 GAO87887.1 - 1.8e-70 237.0 0.6 2.1e-70 236.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.8 GAO87888.1 - 4e-09 36.0 2.1 4e-09 36.0 1.4 2.0 2 0 0 2 2 2 1 RED-like protein N-terminal region GvpG PF05120.7 GAO87888.1 - 0.59 9.9 4.9 0.15 11.8 0.2 2.4 3 0 0 3 3 3 0 Gas vesicle protein G zf-UBR PF02207.15 GAO87889.1 - 1.2e-16 60.1 16.1 2.6e-16 59.0 11.1 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 GAO87889.1 - 0.00035 20.3 1.0 0.00035 20.3 0.7 4.0 4 1 1 5 5 5 1 Ring finger domain ClpS PF02617.12 GAO87889.1 - 0.00047 19.8 0.1 0.0014 18.2 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Daxx PF03344.10 GAO87889.1 - 1.6 7.1 17.0 2.8 6.3 11.8 1.3 1 0 0 1 1 1 0 Daxx Family UCR_UQCRX_QCR9 PF05365.7 GAO87890.1 - 6.1e-26 89.8 1.1 9.1e-26 89.2 0.8 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 GAO87891.1 - 1.4e-13 50.0 6.5 2.7e-13 49.2 4.5 1.5 1 0 0 1 1 1 1 Mago binding Paramyxo_C PF01692.13 GAO87891.1 - 0.3 10.6 9.1 2.9 7.4 6.5 2.0 1 1 1 2 2 2 0 Paramyxovirus non-structural protein c Amino_oxidase PF01593.19 GAO87892.1 - 1.3e-22 80.5 0.0 2.3e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO87892.1 - 6.4e-12 45.3 0.0 2.1e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO87892.1 - 4.4e-08 32.4 0.0 5.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO87892.1 - 0.00076 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO87892.1 - 0.0019 18.5 0.1 2.7 8.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO87892.1 - 0.002 18.2 0.1 0.037 14.0 0.0 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO87892.1 - 0.039 12.8 0.1 0.078 11.8 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 GAO87892.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO87892.1 - 0.14 10.6 0.1 1 7.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein zf-CCCH_2 PF14608.1 GAO87893.1 - 1.1e-08 34.6 56.6 0.00011 22.0 8.4 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 GAO87893.1 - 0.031 14.3 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.17 GAO87894.1 - 4e-59 200.3 0.0 5.5e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FGGY_C PF02782.11 GAO87895.1 - 6.1e-75 251.1 0.4 9.9e-75 250.5 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAO87895.1 - 2.9e-70 236.3 0.0 4.1e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 GAO87896.1 - 2.5e-58 197.2 5.6 3.1e-58 196.9 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pyrophosphatase PF00719.14 GAO87897.1 - 5.6e-43 146.0 0.0 7.6e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase His_Phos_1 PF00300.17 GAO87898.1 - 1.2e-15 57.9 0.8 1.4e-15 57.6 0.5 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dynamitin PF04912.9 GAO87898.1 - 0.075 11.8 0.1 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Dynamitin Glyco_hydro_16 PF00722.16 GAO87899.1 - 1.3e-40 138.6 3.9 2e-40 138.0 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PP2C PF00481.16 GAO87900.1 - 4.6e-54 183.4 0.1 7.9e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 GAO87900.1 - 4.1e-46 153.9 49.1 1.1e-06 28.0 0.1 12.2 7 2 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO87900.1 - 9.6e-41 137.3 55.3 2.5e-10 39.9 1.6 10.7 4 3 7 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 GAO87900.1 - 4.2e-29 101.2 0.0 9.1e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 GAO87900.1 - 1.2e-16 58.2 57.9 0.24 11.5 0.1 17.6 16 2 1 17 17 17 7 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 GAO87900.1 - 2.6e-16 58.6 0.2 2.6e-16 58.6 0.1 2.6 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 GAO87900.1 - 1.9e-08 33.1 42.5 1.7 9.1 0.1 15.2 16 0 0 16 16 15 2 Leucine rich repeat RA PF00788.18 GAO87900.1 - 1.4e-05 25.4 0.0 5.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.1 GAO87900.1 - 0.00053 19.6 4.8 1.1 9.0 0.0 4.1 3 2 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 GAO87900.1 - 0.00074 19.1 11.2 0.99 8.9 0.0 4.4 2 1 1 4 4 4 3 Leucine-rich repeat PP2C_2 PF13672.1 GAO87900.1 - 0.042 13.2 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_6 PF13516.1 GAO87900.1 - 0.14 12.3 45.8 16 5.9 0.2 14.1 15 1 1 16 16 16 0 Leucine Rich repeat MSC PF09402.5 GAO87901.1 - 4.6e-103 344.4 0.0 6.5e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 GAO87901.1 - 2.9e-17 61.8 0.2 7e-17 60.6 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain V-SNARE_C PF12352.3 GAO87901.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF3350 PF11830.3 GAO87901.1 - 0.019 14.9 0.4 2.4 8.2 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) Zn_clus PF00172.13 GAO87902.1 - 0.036 13.9 1.2 0.057 13.3 0.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_topoisoIV PF00521.15 GAO87902.1 - 0.072 11.9 0.0 0.077 11.8 0.0 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Fungal_trans PF04082.13 GAO87903.1 - 2.4e-32 111.8 0.0 4.3e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87903.1 - 1.1e-07 31.5 8.1 2e-07 30.7 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.7 GAO87904.1 - 7.5e-41 139.6 0.0 1.3e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAO87904.1 - 3e-33 114.8 0.0 6e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAO87904.1 - 2.9e-13 49.8 0.0 1.5e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAO87904.1 - 2.2e-10 40.6 0.1 5.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 GAO87904.1 - 0.0017 18.3 0.5 0.032 14.2 0.1 2.7 2 1 0 2 2 2 1 NADH(P)-binding AMP-binding_C PF13193.1 GAO87904.1 - 0.0092 16.9 0.0 0.11 13.4 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 GAO87904.1 - 0.015 15.1 0.4 0.062 13.2 0.3 2.0 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 GAO87904.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAO87904.1 - 0.045 12.4 0.0 0.54 8.9 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAO87904.1 - 0.087 11.6 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 GAO87904.1 - 0.095 12.3 0.2 0.27 10.8 0.2 1.8 1 1 0 1 1 1 0 KR domain IMS PF00817.15 GAO87905.1 - 1.8e-41 141.3 0.0 3.9e-41 140.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAO87905.1 - 4.2e-18 65.4 0.0 9.2e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 GAO87905.1 - 2.2e-16 59.7 13.7 7.7e-09 35.4 0.2 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 GAO87905.1 - 1.7e-06 28.0 0.0 5.3e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 GAO87905.1 - 8.9e-05 22.5 0.0 0.00041 20.4 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 GAO87905.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.2 GAO87905.1 - 0.00068 19.4 0.0 0.0022 17.7 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.3 GAO87905.1 - 0.029 14.3 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus FliG_M PF14841.1 GAO87905.1 - 0.075 13.0 0.2 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 FliG middle domain DUF1805 PF08827.6 GAO87905.1 - 0.095 12.5 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.23 GAO87906.1 - 7.7e-31 105.9 0.0 2.4e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 GAO87907.1 - 1.3e-36 126.1 1.2 1.1e-23 83.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87907.1 - 3.1e-14 52.6 0.2 5.2e-11 42.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 GAO87907.1 - 0.00077 19.2 0.3 0.002 17.9 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 GAO87907.1 - 0.028 14.9 4.8 0.066 13.7 0.0 3.2 2 1 0 2 2 2 0 Protein kinase C terminal domain DUF3591 PF12157.3 GAO87908.1 - 1.2e-197 656.8 0.0 1.6e-197 656.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Methyltransf_15 PF09445.5 GAO87908.1 - 2e-45 154.2 0.0 4.2e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 GAO87908.1 - 9.4e-09 35.3 0.0 2.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAO87908.1 - 1.8e-08 34.1 0.0 3.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 GAO87908.1 - 5e-07 29.4 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 GAO87908.1 - 6e-07 30.0 0.0 2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAO87908.1 - 1.3e-05 24.6 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 GAO87908.1 - 6e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-CCHC_6 PF15288.1 GAO87908.1 - 0.0042 16.7 1.2 0.011 15.3 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAO87908.1 - 0.017 14.9 0.9 0.032 14.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle GRASP55_65 PF04495.9 GAO87909.1 - 3.9e-42 143.5 0.0 2.5e-41 140.8 0.0 1.9 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain ApoO PF09769.4 GAO87910.1 - 3e-50 170.0 0.0 1.5e-49 167.7 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.15 GAO87911.1 - 5.6e-118 394.8 0.0 7.5e-118 394.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 GAO87911.1 - 0.17 11.2 0.4 0.32 10.3 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like GAS PF13851.1 GAO87913.1 - 0.00037 19.7 15.4 0.00037 19.7 10.7 8.2 1 1 8 9 9 9 2 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 GAO87913.1 - 0.0013 18.8 7.5 0.0013 18.8 5.2 8.8 2 2 5 8 8 8 3 Fibrinogen alpha/beta chain family Filament PF00038.16 GAO87913.1 - 0.0025 17.3 39.7 0.0025 17.3 27.5 7.7 2 1 5 8 8 8 3 Intermediate filament protein CENP-Q PF13094.1 GAO87913.1 - 0.008 16.2 10.3 0.008 16.2 7.2 10.7 1 1 8 9 9 9 3 CENP-Q, a CENPA-CAD centromere complex subunit Pox_A_type_inc PF04508.7 GAO87913.1 - 1.3 8.9 0.0 1.3 8.9 0.0 10.0 11 0 0 11 11 11 0 Viral A-type inclusion protein repeat PTPA PF03095.10 GAO87915.1 - 6.3e-111 370.3 0.0 7.4e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_3 PF00933.16 GAO87916.1 - 1.9e-92 309.4 0.0 2.7e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO87916.1 - 1.1e-54 185.3 0.1 5.8e-53 179.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain DUF572 PF04502.8 GAO87916.1 - 6.7e-50 170.1 0.0 8.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fn3-like PF14310.1 GAO87916.1 - 1e-18 67.0 0.4 1.9e-18 66.1 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lambda_Kil PF06301.6 GAO87916.1 - 0.072 12.5 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Cerato-platanin PF07249.7 GAO87916.1 - 0.074 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Cerato-platanin PhoD PF09423.5 GAO87917.1 - 7.1e-163 542.3 1.7 8.2e-163 542.1 1.1 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase PNP_UDP_1 PF01048.15 GAO87918.1 - 5.3e-39 133.5 0.1 6.5e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily 6PGD PF00393.14 GAO87919.1 - 1.1e-64 218.4 0.0 1.5e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAO87919.1 - 1.3e-34 119.4 0.0 3.4e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAO87919.1 - 4.9e-05 23.0 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO87919.1 - 0.00012 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 GAO87919.1 - 0.00077 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAO87919.1 - 0.0013 18.0 0.0 0.0074 15.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 GAO87919.1 - 0.0022 17.4 0.0 0.0051 16.2 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAO87919.1 - 0.019 15.3 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 GAO87919.1 - 0.032 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 GAO87919.1 - 0.034 14.5 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.19 GAO87920.1 - 3.7e-35 121.1 0.0 5.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldedh PF00171.17 GAO87921.1 - 5.2e-109 364.6 0.3 6.5e-109 364.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.13 GAO87922.1 - 8.7e-34 116.9 0.2 1.1e-33 116.6 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Ank_2 PF12796.2 GAO87923.1 - 2.4e-31 107.9 1.5 1.3e-11 44.7 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO87923.1 - 9.1e-25 86.5 3.4 3.5e-09 36.9 0.0 7.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAO87923.1 - 2.5e-21 74.3 0.3 5.2e-05 22.8 0.1 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 GAO87923.1 - 9.8e-17 59.3 0.1 0.0064 16.6 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 GAO87923.1 - 2.5e-16 59.3 0.9 0.00085 19.4 0.0 6.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Clr5 PF14420.1 GAO87923.1 - 1.9e-14 53.2 2.3 3.3e-14 52.5 1.6 1.4 1 0 0 1 1 1 1 Clr5 domain 3-alpha PF03475.9 GAO87923.1 - 0.081 12.6 0.2 0.31 10.8 0.2 2.1 1 0 0 1 1 1 0 3-alpha domain OCD_Mu_crystall PF02423.10 GAO87924.1 - 4.6e-11 42.0 0.0 6.7e-10 38.2 0.0 2.1 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Proteasome_A_N PF10584.4 GAO87924.1 - 0.033 13.4 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Rhamno_transf PF11316.3 GAO87924.1 - 0.058 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase Glyco_tran_WecB PF03808.8 GAO87924.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Fungal_trans PF04082.13 GAO87925.1 - 1.6e-27 95.9 0.1 2.8e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO87925.1 - 4.7e-06 26.4 9.7 9e-06 25.4 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavi_NS5 PF00972.15 GAO87925.1 - 0.042 11.7 0.0 0.06 11.2 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase BUD22 PF09073.5 GAO87926.1 - 8.5e-119 397.4 20.7 9.6e-119 397.2 14.4 1.0 1 0 0 1 1 1 1 BUD22 Complex1_30kDa PF00329.14 GAO87927.1 - 2.7e-35 120.7 0.0 3.9e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 GAO87928.1 - 6.4e-19 67.2 13.4 1.1e-18 66.4 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 GAO87928.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 GAO87928.1 - 0.00012 21.7 7.2 0.0002 20.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 GAO87928.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 GAO87928.1 - 0.0013 18.5 4.8 0.0024 17.5 3.3 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 GAO87928.1 - 0.2 11.3 12.7 0.38 10.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO87928.1 - 1.3 9.0 11.9 2.4 8.2 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1_dh PF00676.15 GAO87929.1 - 4.9e-86 288.1 0.0 6.2e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAO87929.1 - 9e-05 22.0 0.0 0.0011 18.5 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 GAO87929.1 - 0.0082 14.7 0.0 0.014 13.9 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain Glyco_hydro_2 PF00703.16 GAO87930.1 - 1.1e-09 38.6 0.2 4.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAO87930.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ubie_methyltran PF01209.13 GAO87931.1 - 4.7e-80 268.0 0.0 7.5e-80 267.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAO87931.1 - 1.1e-13 51.5 0.0 2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO87931.1 - 2.4e-13 49.9 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO87931.1 - 2.4e-10 40.3 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO87931.1 - 1.5e-09 38.2 0.0 2.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO87931.1 - 2.6e-09 37.3 0.0 6.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO87931.1 - 3.7e-07 30.7 0.0 7.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO87931.1 - 0.00029 20.8 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAO87931.1 - 0.087 12.4 0.0 0.34 10.4 0.0 2.0 3 0 0 3 3 3 0 Hypothetical methyltransferase SIS PF01380.17 GAO87932.1 - 6e-13 48.5 0.0 7e-12 45.0 0.0 2.3 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 GAO87932.1 - 4.5e-07 29.6 0.0 0.00031 20.4 0.1 2.4 1 1 1 2 2 2 2 SIS domain CTP_transf_2 PF01467.21 GAO87933.1 - 8.4e-28 97.3 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 GAO87933.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 1 1 2 2 2 0 Mnd1 family PUF PF00806.14 GAO87933.1 - 0.12 11.9 0.3 41 3.9 0.0 3.2 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat HECT PF00632.20 GAO87934.1 - 7.6e-86 288.1 0.0 1.2e-85 287.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 GAO87934.1 - 0.0029 17.5 0.2 0.48 10.6 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 GAO87934.1 - 0.0029 17.3 0.4 3.5 7.5 0.0 4.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat 4HBT PF03061.17 GAO87935.1 - 6.5e-10 38.9 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-C3HC4 PF00097.20 GAO87936.1 - 0.0068 16.0 4.4 0.018 14.6 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO87936.1 - 0.0083 16.1 7.5 0.024 14.6 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2765 PF10963.3 GAO87936.1 - 0.061 13.2 0.0 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2765) zf-RING_2 PF13639.1 GAO87936.1 - 0.15 11.8 11.6 0.033 14.0 4.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 GAO87936.1 - 0.17 11.6 4.5 0.37 10.5 3.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 GAO87936.1 - 2.6 7.8 10.7 0.47 10.2 4.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain DEAD PF00270.24 GAO87937.1 - 9.8e-43 145.5 0.0 2.3e-42 144.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO87937.1 - 4.4e-22 77.7 0.0 1.3e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO87937.1 - 0.0086 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 GAO87937.1 - 0.011 15.8 0.1 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2147 PF09917.4 GAO87937.1 - 0.094 12.9 2.5 0.62 10.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) GCN5L1 PF06320.8 GAO87937.1 - 0.33 10.7 6.0 0.83 9.4 0.0 3.2 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Nop14 PF04147.7 GAO87937.1 - 0.5 8.2 14.4 0.78 7.5 10.0 1.3 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 GAO87937.1 - 1.3 8.8 10.3 3.5 7.4 7.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FtsJ PF01728.14 GAO87938.1 - 2.4e-63 213.4 0.0 3e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FAD_binding_1 PF00667.15 GAO87939.1 - 8.5e-61 205.1 0.0 1.5e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAO87939.1 - 3.3e-11 43.7 0.0 1.1e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 GAO87939.1 - 1.3e-09 38.1 0.1 3.2e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 GAO87939.1 - 0.00092 19.1 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain NAD_binding_10 PF13460.1 GAO87940.1 - 2.5e-11 43.9 0.5 3e-11 43.6 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO87940.1 - 7.2e-06 25.5 0.0 7.4e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO87940.1 - 2.8e-05 23.5 0.0 4.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAO87940.1 - 3e-05 24.3 0.0 0.0002 21.6 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAO87940.1 - 7.7e-05 21.7 0.1 0.046 12.6 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein HIM1 PF08732.5 GAO87940.1 - 0.015 13.8 0.0 0.023 13.1 0.0 1.2 1 0 0 1 1 1 0 HIM1 DUF982 PF06169.7 GAO87940.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Ldh_1_N PF00056.18 GAO87940.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO87940.1 - 0.093 12.6 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Proteasome PF00227.21 GAO87942.1 - 2.7e-61 206.1 0.2 3.3e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAO87942.1 - 3.1e-14 51.9 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FF PF01846.14 GAO87943.1 - 1.6e-12 47.1 14.2 6.4e-11 42.0 0.1 3.9 4 0 0 4 4 4 3 FF domain WW PF00397.21 GAO87943.1 - 7.8e-09 35.2 8.2 1.4e-08 34.4 1.7 3.2 3 0 0 3 3 3 1 WW domain TFIIA PF03153.8 GAO87944.1 - 0.00078 19.4 21.2 0.001 19.0 14.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Takusan PF04822.8 GAO87944.1 - 0.92 9.3 5.9 2.8 7.7 4.1 1.7 1 0 0 1 1 1 0 Takusan Seryl_tRNA_N PF02403.17 GAO87944.1 - 1.3 9.0 8.7 0.28 11.2 2.9 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TFIIS_M PF07500.9 GAO87945.1 - 1.4e-25 89.5 0.0 3.8e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 GAO87945.1 - 9.3e-21 74.5 0.0 1.9e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 GAO87945.1 - 2.2e-10 40.0 11.8 3.7e-10 39.3 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 GAO87945.1 - 0.031 14.4 0.5 0.031 14.4 0.3 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 GAO87945.1 - 0.035 13.4 5.1 0.057 12.7 3.6 1.4 1 0 0 1 1 1 0 PHD-finger LUC7 PF03194.10 GAO87946.1 - 7.5e-74 248.4 2.1 9.2e-74 248.1 1.4 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 GAO87946.1 - 0.024 14.1 0.1 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.6 GAO87946.1 - 0.031 12.9 2.2 0.071 11.7 1.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 GAO87946.1 - 0.044 12.2 1.3 0.047 12.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain Prefoldin PF02996.12 GAO87946.1 - 0.13 11.9 1.9 0.54 9.9 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 GAO87946.1 - 0.16 11.8 3.2 4 7.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Snf7 PF03357.16 GAO87946.1 - 1.5 8.2 6.6 1.3 8.3 2.8 2.1 2 1 0 2 2 2 0 Snf7 Gpi16 PF04113.9 GAO87947.1 - 3.3e-248 824.3 0.0 4.2e-248 823.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component NfeD PF01957.13 GAO87947.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding eIF3_N PF09440.5 GAO87949.1 - 1.5 8.9 3.8 3 8.0 2.6 1.4 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Borrelia_P83 PF05262.6 GAO87949.1 - 7.5 4.7 11.9 10 4.2 8.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Tannase PF07519.6 GAO87950.1 - 4.9e-123 411.3 3.9 6.2e-123 410.9 2.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAO87950.1 - 3.4e-06 26.8 0.0 0.01 15.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO87950.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO87950.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dodecin PF07311.7 GAO87951.1 - 0.82 9.7 3.2 1.3 9.1 0.4 2.7 2 1 1 3 3 3 0 Dodecin Reo_sigmaC PF04582.7 GAO87951.1 - 1.4 7.9 19.1 0.25 10.4 4.7 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 GAO87951.1 - 5.2 7.1 17.5 1.4 9.0 2.2 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 GAO87951.1 - 9.1 6.6 14.4 8.6 6.7 1.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Cytochrom_C_2 PF01322.15 GAO87951.1 - 10 6.7 11.7 3.1 8.3 2.5 3.3 2 2 0 2 2 2 0 Cytochrome C' Ribosomal_L6 PF00347.18 GAO87952.1 - 1.5e-24 86.2 0.0 4.1e-13 49.6 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 GAO87953.1 - 2.9e-55 187.4 0.7 4.8e-55 186.7 0.5 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 GAO87954.1 - 9.2e-25 86.9 0.0 3.5e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 GAO87954.1 - 4e-11 42.7 1.3 8.2e-11 41.7 0.9 1.5 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 GAO87954.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 ENTH domain ABM PF03992.11 GAO87955.1 - 0.00022 21.2 1.7 0.1 12.6 0.4 3.0 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Flavoprotein PF02441.14 GAO87956.1 - 7.9e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein DUF1391 PF07151.7 GAO87956.1 - 0.03 13.8 0.2 0.074 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) MFS_1 PF07690.11 GAO87957.1 - 5.6e-45 153.5 45.5 1e-44 152.7 31.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO87957.1 - 7.7e-16 57.6 5.2 7.7e-16 57.6 3.6 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.4 GAO87957.1 - 0.4 9.8 2.5 0.26 10.4 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) WTX PF09422.5 GAO87958.1 - 7.3e-05 21.9 12.0 9.4e-05 21.5 8.3 1.0 1 0 0 1 1 1 1 WTX protein DUF2011 PF09428.5 GAO87959.1 - 1.2e-44 151.3 4.4 1.9e-44 150.7 3.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) adh_short_C2 PF13561.1 GAO87959.1 - 3.7e-34 118.5 0.0 6e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO87959.1 - 3.4e-27 95.4 0.1 3.4e-27 95.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO87959.1 - 4e-07 29.8 1.4 4.3e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAO87959.1 - 0.0003 20.2 0.1 0.00065 19.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO87959.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAO87959.1 - 0.04 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAO87959.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LAMTOR PF15454.1 GAO87960.1 - 5.5e-19 68.2 0.2 1e-17 64.1 0.2 2.2 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.21 GAO87961.1 - 3.2e-35 120.5 0.2 4.1e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG12 PF04110.8 GAO87962.1 - 1.6e-29 101.9 0.0 2.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 GAO87962.1 - 0.059 13.3 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 GAO87963.1 - 2.1e-106 354.8 1.2 2.4e-106 354.6 0.9 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 GAO87963.1 - 5.6e-08 32.2 2.3 3.1e-07 29.8 1.6 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Dfp1_Him1_M PF08630.5 GAO87964.1 - 7.5e-45 151.7 0.0 2.6e-44 150.0 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 GAO87964.1 - 4.1e-26 90.3 0.5 7e-26 89.6 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 GAO87964.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Peptidase_M24 PF00557.19 GAO87965.1 - 3.7e-49 167.1 0.0 6.6e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAO87965.1 - 1.2e-35 121.8 0.0 2.2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pyridox_ox_2 PF12900.2 GAO87966.1 - 2.2e-37 128.0 0.0 2.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 GAO87967.1 - 1.8e-39 135.2 0.0 8.8e-39 133.0 0.0 1.8 1 1 0 1 1 1 1 Sir2 family DUF4231 PF14015.1 GAO87967.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SNF2_N PF00176.18 GAO87968.1 - 3.7e-78 262.3 0.1 6.7e-78 261.5 0.1 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO87968.1 - 5.6e-11 42.1 0.0 1.9e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO87968.1 - 1.3e-08 34.5 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 GAO87968.1 - 0.21 10.3 9.5 1.8 7.3 0.0 4.1 4 0 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 GAO87969.1 - 5.6e-60 202.6 0.0 8.7e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO87969.1 - 2.9e-31 108.4 0.0 4.1e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO87969.1 - 4.9e-05 22.4 0.0 7.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO87969.1 - 0.0087 15.8 2.3 0.01 15.5 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO87969.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAO87969.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF605 PF04652.11 GAO87969.1 - 0.28 10.5 12.1 0.42 9.9 8.4 1.2 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 GAO87969.1 - 3.6 6.8 8.0 7.4 5.8 5.6 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Cellulase PF00150.13 GAO87970.1 - 7.5e-13 48.3 0.4 1.4e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4614 PF15391.1 GAO87970.1 - 0.021 14.6 1.7 0.04 13.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) EphA2_TM PF14575.1 GAO87970.1 - 0.12 12.7 0.0 0.5 10.8 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HATPase_c PF02518.21 GAO87971.1 - 5.9e-18 64.6 0.1 1.2e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO87971.1 - 2.6e-16 59.6 0.0 1e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAO87971.1 - 2.2e-14 53.2 0.5 7.3e-14 51.5 0.3 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.15 GAO87971.1 - 0.00013 21.2 0.0 0.00052 19.1 0.0 1.9 2 0 0 2 2 2 1 Phytochrome region PAS_9 PF13426.1 GAO87971.1 - 0.0022 18.3 0.0 0.0059 16.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain GAF PF01590.21 GAO87971.1 - 0.0078 16.3 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.1 GAO87971.1 - 0.017 14.7 1.0 0.049 13.2 0.1 2.2 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_2 PF08446.6 GAO87971.1 - 0.017 15.5 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold Reo_sigmaC PF04582.7 GAO87972.1 - 0.0014 17.8 3.3 0.0014 17.8 2.3 5.4 3 3 1 4 4 4 3 Reovirus sigma C capsid protein GAS PF13851.1 GAO87972.1 - 0.0021 17.2 18.1 0.0021 17.2 12.5 6.2 2 2 4 6 6 6 2 Growth-arrest specific micro-tubule binding DIM PF08194.7 GAO87973.1 - 0.11 12.4 0.7 0.11 12.4 0.5 2.2 2 0 0 2 2 2 0 DIM protein FNIP_N PF14636.1 GAO87974.1 - 0.0063 16.9 0.2 0.05 14.0 0.0 2.2 2 0 0 2 2 2 1 Folliculin-interacting protein N-terminus TraF PF13728.1 GAO87974.1 - 0.089 12.2 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein CorA PF01544.13 GAO87975.1 - 6.4e-08 31.9 1.7 4.3e-07 29.2 0.5 2.5 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein PRT_C PF08372.5 GAO87975.1 - 0.046 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF2096 PF09869.4 GAO87975.1 - 0.18 11.7 2.6 0.38 10.6 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) FixQ PF05545.6 GAO87975.1 - 0.44 10.2 5.8 3.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Fig1 PF12351.3 GAO87976.1 - 2.3e-56 190.5 2.0 2.7e-56 190.3 1.4 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 GAO87976.1 - 2.8e-07 30.3 0.9 6.1e-07 29.2 0.6 1.5 1 1 0 1 1 1 1 SUR7/PalI family FtsX PF02687.16 GAO87976.1 - 1.8 8.3 14.7 2.3 7.9 0.3 2.3 2 0 0 2 2 2 0 FtsX-like permease family EI24 PF07264.6 GAO87976.1 - 2.8 7.3 11.6 3.7 6.9 4.4 2.3 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Tic20 PF09685.5 GAO87976.1 - 8.6 6.3 10.2 1.6e+02 2.3 7.1 2.2 1 1 0 1 1 1 0 Tic20-like protein Ank_2 PF12796.2 GAO87977.1 - 3.9e-70 232.2 8.2 1e-18 67.4 0.3 5.4 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO87977.1 - 7.2e-52 170.7 10.4 7.6e-10 38.0 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAO87977.1 - 4.1e-44 148.2 7.2 1e-11 45.0 0.2 6.2 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO87977.1 - 3.7e-40 135.0 22.3 1e-09 38.3 0.1 6.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO87977.1 - 9.6e-39 127.5 1.2 3.2e-06 26.8 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat RVP PF00077.15 GAO87977.1 - 0.11 12.4 0.1 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease Chitin_synth_1 PF01644.12 GAO87980.1 - 3.7e-67 225.1 0.0 5.7e-67 224.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 GAO87980.1 - 1.4e-25 89.6 0.0 6e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 GAO87980.1 - 2.7e-25 87.8 0.2 6.3e-25 86.6 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 GAO87980.1 - 4.8e-07 29.6 12.5 6.1e-07 29.3 6.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO87980.1 - 1e-05 25.4 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GBA2_N PF12215.3 GAO87981.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Herpes_U34 PF04541.8 GAO87981.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 adh_short PF00106.20 GAO87982.1 - 2.3e-22 79.6 0.1 5.6e-22 78.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO87982.1 - 2.5e-12 47.0 0.0 4.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 GAO87982.1 - 1.4e-11 43.6 0.4 1.8e-10 39.9 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 GAO87982.1 - 3e-07 30.2 0.0 7.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO87982.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO87982.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF1914 PF08932.5 GAO87983.1 - 0.016 15.2 0.2 0.035 14.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) WSC PF01822.14 GAO87984.1 - 1.2e-15 57.1 0.8 1.2e-15 57.1 0.6 2.1 2 0 0 2 2 2 1 WSC domain CASP_C PF08172.7 GAO87984.1 - 0.0018 17.3 0.7 0.0018 17.3 0.5 2.2 3 0 0 3 3 3 1 CASP C terminal TFR_dimer PF04253.10 GAO87984.1 - 0.0044 16.6 0.1 0.009 15.5 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Filament PF00038.16 GAO87984.1 - 0.024 14.1 0.9 0.039 13.4 0.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein AnfO_nitrog PF09582.5 GAO87984.1 - 0.03 13.4 0.4 0.078 12.1 0.3 1.7 1 1 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Tropomyosin_1 PF12718.2 GAO87984.1 - 0.061 13.1 0.8 0.096 12.5 0.3 1.5 1 1 0 1 1 1 0 Tropomyosin like TBPIP PF07106.8 GAO87984.1 - 0.15 11.6 1.0 0.75 9.3 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 GAO87984.1 - 7.6 6.0 10.3 0.31 10.6 0.3 2.5 2 1 0 2 2 2 0 IncA protein adh_short PF00106.20 GAO87985.1 - 4.2e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO87985.1 - 0.00083 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF4379 PF14311.1 GAO87985.1 - 0.024 14.4 1.9 0.089 12.6 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) GFA PF04828.9 GAO87986.1 - 1.9e-22 79.0 0.1 2.8e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 GAO87986.1 - 0.0033 17.1 1.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Metallothio_Euk PF12749.2 GAO87986.1 - 1.3 9.0 6.7 2.7 8.0 4.6 1.5 1 1 0 1 1 1 0 Eukaryotic metallothionein Sugar_tr PF00083.19 GAO87987.1 - 1.5e-88 297.3 20.2 1.9e-88 297.0 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO87987.1 - 1.1e-13 50.6 59.1 5.4e-10 38.5 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 GAO87987.1 - 0.0086 15.0 0.2 0.018 13.9 0.2 1.5 1 0 0 1 1 1 1 UAA transporter family p450 PF00067.17 GAO87988.1 - 7.2e-68 229.1 0.0 8.7e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Big_3_2 PF12245.3 GAO87990.1 - 0.0022 17.4 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) RHS_repeat PF05593.9 GAO87991.1 - 2.3e-18 65.8 49.3 3.3e-05 23.9 0.3 14.6 11 4 3 15 15 15 8 RHS Repeat DUF3328 PF11807.3 GAO87993.1 - 1.8e-46 158.6 0.0 2.1e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YscK PF06578.7 GAO87993.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) CVNH PF08881.5 GAO87995.1 - 1.4e-12 47.7 0.0 8.6e-08 32.3 0.0 4.0 3 1 1 4 4 4 2 CVNH domain SF-assemblin PF06705.6 GAO87995.1 - 1.3 8.0 18.3 0.03 13.4 6.1 2.7 2 2 0 2 2 2 0 SF-assemblin/beta giardin ATC_hydrolase PF14196.1 GAO87995.1 - 7.9 6.8 17.5 1.1 9.5 0.7 3.4 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF4200 PF13863.1 GAO87996.1 - 0.063 13.2 31.0 0.7 9.8 2.2 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 GAO87996.1 - 0.078 11.4 12.1 0.21 10.0 1.3 2.5 2 0 0 2 2 2 0 AAA domain DUF2935 PF11155.3 GAO87996.1 - 0.45 10.6 4.5 17 5.5 2.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) SPX PF03105.14 GAO87996.1 - 0.77 9.4 7.0 0.28 10.9 1.3 2.3 2 1 0 2 2 2 0 SPX domain DivIC PF04977.10 GAO87996.1 - 0.88 9.1 25.6 0.14 11.6 2.2 4.3 3 1 1 4 4 4 0 Septum formation initiator Fib_alpha PF08702.5 GAO87996.1 - 6.6 6.8 11.5 2.2 8.4 1.3 3.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Aldo_ket_red PF00248.16 GAO87998.1 - 6.6e-35 120.3 0.0 1e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 GAO87998.1 - 3.3e-26 92.1 0.3 1.5e-25 90.0 0.1 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GFO_IDH_MocA PF01408.17 GAO87998.1 - 3.8e-14 53.2 0.0 1.7e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO87998.1 - 5.7e-06 26.1 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 GAO87998.1 - 0.0055 17.0 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 GAO87998.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Abhydrolase_3 PF07859.8 GAO87999.1 - 8e-13 48.4 0.4 0.00025 20.6 0.0 3.8 3 1 1 4 4 4 3 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO87999.1 - 0.0034 16.0 0.1 1.7 7.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) PAN_4 PF14295.1 GAO88002.1 - 3.7e-05 23.3 1.1 3.7e-05 23.3 0.8 4.9 5 1 0 5 5 5 1 PAN domain PAN_3 PF08277.7 GAO88002.1 - 0.0023 17.5 5.5 0.0099 15.4 0.1 3.0 3 0 0 3 3 3 1 PAN-like domain Apolipoprotein PF01442.13 GAO88002.1 - 0.38 10.2 29.9 0.67 9.4 20.8 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 GAO88002.1 - 7.2 4.0 17.8 10 3.5 12.3 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.3 GAO88002.1 - 7.7 3.7 36.5 10 3.2 25.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Glyco_hydro_61 PF03443.9 GAO88003.1 - 1.4e-43 149.2 0.8 6.7e-43 147.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAO88003.1 - 5.6e-11 41.8 12.1 3e-10 39.5 8.4 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain RTA1 PF04479.8 GAO88004.1 - 2.8e-58 197.0 7.4 3.8e-58 196.6 5.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Peptidase_M20 PF01546.23 GAO88005.1 - 1.7e-19 70.1 0.1 2.7e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO88005.1 - 1.5e-13 50.4 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Ank_2 PF12796.2 GAO88006.1 - 4.6e-80 264.0 9.9 5.7e-17 61.8 0.0 7.1 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88006.1 - 2.6e-62 203.6 18.6 3.9e-09 35.8 0.1 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 GAO88006.1 - 2.1e-49 165.0 12.6 4.3e-09 36.6 0.0 8.5 4 4 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88006.1 - 3e-46 150.7 7.7 0.0035 17.4 0.0 12.0 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 GAO88006.1 - 3.5e-44 147.8 23.6 1.7e-07 31.2 0.2 10.8 2 2 10 12 12 12 9 Ankyrin repeats (many copies) F-box-like PF12937.2 GAO88006.1 - 0.033 13.8 0.1 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1654 PF07867.6 GAO88006.1 - 0.11 11.8 0.3 0.53 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) MFS_1 PF07690.11 GAO88007.1 - 1.6e-26 92.8 46.7 3.9e-26 91.6 32.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Condensation PF00668.15 GAO88008.1 - 0.033 13.0 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Zn_clus PF00172.13 GAO88009.1 - 8.9e-08 31.9 12.1 8.9e-08 31.9 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 GAO88009.1 - 0.089 11.1 3.4 0.13 10.5 2.3 1.1 1 0 0 1 1 1 0 Per os infectivity Aminotran_1_2 PF00155.16 GAO88010.1 - 4.3e-35 121.3 0.0 5.7e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO88010.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_M19 PF01244.16 GAO88011.1 - 8.2e-92 307.5 0.1 1e-90 303.9 0.0 1.9 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AMP-binding PF00501.23 GAO88012.1 - 2.2e-152 507.2 0.1 2.6e-79 266.5 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO88012.1 - 3.2e-52 177.2 0.1 1.5e-25 89.6 0.0 2.7 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO88012.1 - 8.9e-27 93.1 0.0 1.6e-09 37.8 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO88012.1 - 3.4e-11 43.3 0.0 1.2e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain p450 PF00067.17 GAO88013.1 - 9.7e-46 156.2 0.0 1.2e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 GAO88013.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein Methyltransf_2 PF00891.13 GAO88014.1 - 3e-35 121.5 0.0 4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO88014.1 - 0.007 16.9 0.0 0.027 15.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MarR_2 PF12802.2 GAO88014.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 MarR family GST_C PF00043.20 GAO88015.1 - 9.2e-08 31.9 0.1 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO88015.1 - 7.9e-07 28.9 0.1 2.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO88015.1 - 2.2e-06 27.7 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO88015.1 - 4.8e-05 23.7 0.1 7.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO88015.1 - 0.088 12.7 0.1 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 GAO88017.1 - 3e-37 128.1 51.5 3e-37 128.1 35.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO88017.1 - 4e-20 71.5 20.6 5.4e-20 71.1 14.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_23 PF13489.1 GAO88018.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88018.1 - 0.0069 15.9 0.0 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88018.1 - 0.059 13.9 0.0 0.29 11.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 GAO88019.1 - 6.3e-37 127.1 0.0 7.6e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAO88019.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.9 GAO88020.1 - 8.9e-20 71.4 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88020.1 - 1.7e-05 24.6 0.2 0.029 14.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 GAO88020.1 - 3.2e-05 22.9 0.4 0.0001 21.3 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO88020.1 - 0.00068 18.7 0.1 0.0013 17.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAO88020.1 - 0.00085 17.8 0.1 0.018 13.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO88020.1 - 0.0011 17.9 0.1 0.0098 14.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAO88020.1 - 0.0014 18.6 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO88020.1 - 0.0019 17.3 0.1 0.0033 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 GAO88020.1 - 0.048 12.5 0.1 4.6 6.0 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAO88020.1 - 0.05 13.6 0.2 4.2 7.3 0.1 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1857 PF08982.6 GAO88021.1 - 1.1e-41 141.9 0.0 1.2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Fungal_trans_2 PF11951.3 GAO88022.1 - 0.0055 15.3 0.4 0.0082 14.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAO88025.1 - 0.00021 20.2 1.1 0.029 13.2 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain 2HCT PF03390.10 GAO88025.1 - 0.023 13.0 0.0 0.037 12.4 0.0 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Prok-E2_C PF14459.1 GAO88025.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family C NmrA PF05368.8 GAO88026.1 - 5.1e-20 71.7 0.0 7.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO88026.1 - 4.9e-12 46.2 0.1 6.7e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO88026.1 - 1.6e-07 30.7 0.1 2.6e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAO88026.1 - 5e-05 22.8 0.0 9.8e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAO88026.1 - 0.0001 22.4 0.1 0.00027 21.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 GAO88026.1 - 0.00065 19.5 0.1 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAO88026.1 - 0.0018 18.6 0.3 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 GAO88026.1 - 0.0027 16.4 0.0 0.0043 15.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAO88026.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAO88026.1 - 0.032 13.8 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO88026.1 - 0.064 12.4 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 GAO88026.1 - 0.11 12.2 0.5 2.2 8.1 0.2 2.6 1 1 1 2 2 2 0 ThiF family Glyco_hydro_18 PF00704.23 GAO88027.1 - 2.3e-75 254.2 5.2 2.6e-75 254.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADIP PF11559.3 GAO88028.1 - 0.011 15.6 5.4 0.011 15.6 3.8 4.1 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 GAO88028.1 - 0.018 14.1 6.0 0.78 8.8 3.3 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 GAO88028.1 - 0.019 13.4 19.5 0.034 12.6 13.5 1.4 1 0 0 1 1 1 0 AAA domain CRT10 PF08728.5 GAO88028.1 - 0.12 10.2 8.1 0.18 9.7 5.6 1.1 1 0 0 1 1 1 0 CRT10 Adeno_PIX PF03955.9 GAO88028.1 - 0.33 11.4 16.1 0.52 10.8 1.5 3.1 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF948 PF06103.6 GAO88028.1 - 0.45 10.4 5.9 1 9.2 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EMP24_GP25L PF01105.19 GAO88028.1 - 2.8 7.5 18.5 0.2 11.3 7.4 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Laminin_II PF06009.7 GAO88028.1 - 3.2 7.5 20.1 1.8 8.3 5.1 3.4 1 1 2 3 3 3 0 Laminin Domain II Baculo_p24 PF05073.7 GAO88028.1 - 4.5 6.7 10.2 4.3 6.8 5.7 2.0 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Prominin PF05478.6 GAO88028.1 - 5.9 4.2 10.1 9.4 3.6 7.0 1.3 1 0 0 1 1 1 0 Prominin Lyase_aromatic PF00221.14 GAO88029.1 - 1.7e-91 307.0 1.0 4.7e-91 305.5 0.1 1.9 2 0 0 2 2 2 1 Aromatic amino acid lyase Peptidase_M20 PF01546.23 GAO88029.1 - 2.5e-19 69.5 0.0 4.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO88029.1 - 6e-08 32.4 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO88029.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 3HCDH_N PF02737.13 GAO88030.1 - 2.9e-26 92.2 0.0 4.4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipocalin_5 PF13924.1 GAO88030.1 - 2.2e-25 88.9 0.0 3.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain 3HCDH PF00725.17 GAO88030.1 - 4.4e-14 52.6 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAO88030.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO88030.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sdh_cyt PF01127.17 GAO88031.1 - 9.5e-25 86.7 6.5 9.5e-25 86.7 4.5 1.4 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_3 PF13706.1 GAO88031.1 - 0.046 13.1 0.3 0.14 11.6 0.2 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix p450 PF00067.17 GAO88033.1 - 1.5e-50 172.1 0.1 3.1e-37 128.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 GFA PF04828.9 GAO88034.1 - 0.00043 20.1 1.8 0.0014 18.5 1.2 1.9 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Iron_permease PF04120.7 GAO88035.1 - 1.5e-35 121.6 10.9 7.3e-18 64.4 0.0 4.3 4 0 0 4 4 4 4 Low affinity iron permease DUF2556 PF10831.3 GAO88035.1 - 0.097 12.3 0.9 16 5.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) RseC_MucC PF04246.7 GAO88035.1 - 2.2 7.8 8.4 3 7.4 0.4 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Cytochrom_C PF00034.16 GAO88036.1 - 1.3e-09 38.7 0.1 3.7e-09 37.2 0.0 1.8 2 1 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAO88036.1 - 5.8e-08 32.7 2.7 3.3e-07 30.3 1.9 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAO88036.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Haem_bd PF14376.1 GAO88036.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain Zn_clus PF00172.13 GAO88037.1 - 8.8e-07 28.7 6.4 2e-06 27.6 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 GAO88038.1 - 9.4e-73 240.6 18.3 5e-19 68.4 0.1 6.0 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88038.1 - 1.3e-51 169.8 19.4 1.4e-09 37.2 0.1 10.6 10 1 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 GAO88038.1 - 1.6e-47 154.7 9.2 3.7e-07 29.7 0.0 11.4 11 1 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 GAO88038.1 - 3.5e-45 151.6 11.4 1.1e-14 54.3 0.1 7.5 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO88038.1 - 7.9e-38 127.6 7.6 1.2e-10 41.2 0.1 8.7 4 1 3 8 8 8 6 Ankyrin repeats (many copies) ESX-1_EspG PF14011.1 GAO88038.1 - 0.00013 21.3 0.2 0.00024 20.4 0.1 1.4 1 0 0 1 1 1 1 EspG family DUF3435 PF11917.3 GAO88039.1 - 3.3e-25 88.6 1.1 4.1e-25 88.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DnaI_N PF07319.6 GAO88039.1 - 0.14 12.4 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus zf-C3HC4_3 PF13920.1 GAO88039.1 - 0.15 11.7 0.6 0.25 11.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 GAO88040.1 - 1.4e-87 288.1 20.0 1e-17 64.2 0.6 7.3 3 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88040.1 - 2.6e-81 263.6 42.5 8.6e-08 31.6 0.1 15.5 14 1 1 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 GAO88040.1 - 9.4e-52 172.5 16.0 2.3e-05 24.7 0.1 12.4 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO88040.1 - 8.1e-48 159.3 30.5 5.7e-06 26.4 0.6 12.8 3 3 11 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88040.1 - 1.8e-44 145.2 17.5 0.0042 17.1 0.0 14.3 14 0 0 14 14 14 12 Ankyrin repeat NACHT PF05729.7 GAO88040.1 - 6.2e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 GAO88040.1 - 1.8e-07 30.3 0.7 9.7e-07 27.9 0.5 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 GAO88040.1 - 0.0016 18.4 2.5 0.0037 17.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain Spidroin_MaSp PF11260.3 GAO88040.1 - 0.014 15.4 0.3 50 4.0 0.0 5.1 7 0 0 7 7 7 0 Major ampullate spidroin 1 and 2 AAA_22 PF13401.1 GAO88040.1 - 0.077 13.1 0.0 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAO88040.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF3723 PF12520.3 GAO88041.1 - 3.7e-50 170.8 0.0 4.8e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) WXG100 PF06013.7 GAO88042.1 - 0.0042 17.0 0.4 0.0065 16.4 0.3 1.3 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Syntaxin PF00804.20 GAO88042.1 - 0.075 13.1 0.8 1.4 9.1 0.2 2.1 1 1 1 2 2 2 0 Syntaxin CENP-F_leu_zip PF10473.4 GAO88042.1 - 0.078 12.8 1.1 0.096 12.5 0.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PilM_2 PF11104.3 GAO88043.1 - 0.053 12.3 0.1 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; FAD_binding_8 PF08022.7 GAO88044.1 - 3.8e-08 33.1 0.0 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 GAO88044.1 - 3.8e-07 30.1 0.0 1.7e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Patatin PF01734.17 GAO88044.1 - 1e-05 25.5 0.4 0.00032 20.6 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase CCDC155 PF14662.1 GAO88044.1 - 0.002 17.7 5.2 0.0027 17.3 2.0 2.0 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 SRF-TF PF00319.13 GAO88044.1 - 0.0033 16.6 0.1 0.0094 15.1 0.1 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GAS PF13851.1 GAO88044.1 - 0.0085 15.3 4.8 0.015 14.5 3.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Ferric_reduct PF01794.14 GAO88044.1 - 0.019 15.0 6.8 0.12 12.4 0.7 2.7 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF724 PF05266.9 GAO88044.1 - 0.099 12.2 3.1 0.19 11.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.2 GAO88044.1 - 0.16 11.7 4.9 0.29 10.9 3.4 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 GAO88044.1 - 0.17 12.2 1.8 0.52 10.6 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TBPIP PF07106.8 GAO88044.1 - 0.52 9.8 5.5 1.1 8.7 3.8 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 GAO88044.1 - 1.5 8.8 5.0 1 9.3 2.0 1.8 1 1 1 2 2 2 0 bZIP transcription factor DUF812 PF05667.6 GAO88045.1 - 0.00058 18.5 1.8 0.0031 16.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF812) DUF3472 PF11958.3 GAO88045.1 - 0.0094 16.3 0.2 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DnaJ-X PF14308.1 GAO88045.1 - 0.037 13.3 0.1 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 X-domain of DnaJ-containing Ank_2 PF12796.2 GAO88047.1 - 4.1e-38 129.5 2.3 1.4e-21 76.5 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88047.1 - 1.6e-30 103.3 10.0 1.1e-07 31.2 0.2 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAO88047.1 - 4.4e-29 100.3 4.1 4.5e-11 42.9 0.0 5.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88047.1 - 1.1e-23 80.9 8.8 0.0004 20.3 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 GAO88047.1 - 2.4e-21 75.2 3.7 3.8e-09 36.5 0.0 4.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) CorA PF01544.13 GAO88047.1 - 2.1e-16 59.8 0.5 3.8e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 GAO88047.1 - 1.3e-06 27.7 2.7 2.2e-06 27.0 1.9 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF1673 PF07895.6 GAO88047.1 - 0.038 13.5 0.9 0.097 12.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Na_H_Exchanger PF00999.16 GAO88047.1 - 0.094 11.2 0.4 0.14 10.6 0.3 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family DUF1843 PF08898.5 GAO88047.1 - 0.62 10.1 2.9 1.1 9.4 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Baculo_LEF-11 PF06385.7 GAO88048.1 - 0.014 15.4 0.3 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Pkinase PF00069.20 GAO88052.1 - 3.4e-13 49.3 0.0 5.6e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88052.1 - 2.1e-11 43.4 0.0 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAO88052.1 - 2.8e-07 30.4 0.9 0.00031 20.5 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO88052.1 - 0.00066 19.3 0.1 0.2 11.2 0.0 2.3 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.9 GAO88052.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MKT1_C PF12246.3 GAO88052.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF2761 PF10959.3 GAO88053.1 - 0.14 11.7 0.1 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Hormone_recep PF00104.25 GAO88053.1 - 0.15 11.1 2.6 0.19 10.8 0.6 1.9 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Gp58 PF07902.6 GAO88054.1 - 0.088 11.0 0.5 0.43 8.7 0.1 1.8 2 0 0 2 2 2 0 gp58-like protein Spc7 PF08317.6 GAO88054.1 - 0.21 10.1 4.4 0.33 9.5 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MreB_Mbl PF06723.8 GAO88055.1 - 0.074 11.6 0.0 0.27 9.7 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 GAO88055.1 - 0.12 10.2 0.0 0.55 8.0 0.0 1.9 1 1 0 1 1 1 0 Hsp70 protein NAD_binding_10 PF13460.1 GAO88056.1 - 7.7e-12 45.5 0.0 1.2e-11 44.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO88056.1 - 3.1e-11 42.9 0.0 5e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAO88056.1 - 0.0068 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1643 PF07799.7 GAO88056.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Fungal_trans PF04082.13 GAO88057.1 - 2.4e-27 95.4 1.4 3.7e-27 94.8 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAO88057.1 - 2.2e-15 56.9 0.1 3.8e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88057.1 - 3.6e-08 33.2 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Gal4_dimer PF03902.8 GAO88057.1 - 5.7e-08 32.5 0.4 1.2e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain NmrA PF05368.8 GAO88057.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Permease PF02405.11 GAO88057.1 - 0.083 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Permease GST_N PF02798.15 GAO88058.1 - 1e-15 57.6 0.0 2.9e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO88058.1 - 1.4e-14 54.0 0.0 2.9e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO88058.1 - 1.9e-11 43.8 0.0 4.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO88058.1 - 6.4e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO88058.1 - 1e-05 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO88058.1 - 0.00042 20.7 0.0 0.00066 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CRAL_TRIO PF00650.15 GAO88059.1 - 1.9e-27 95.6 0.0 3.3e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAO88059.1 - 1.4e-06 28.2 0.0 0.00054 19.8 0.0 2.2 2 0 0 2 2 2 2 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO88059.1 - 1.5e-05 25.0 0.0 5.1e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Oxidored_FMN PF00724.15 GAO88060.1 - 3.4e-73 246.6 0.1 2.7e-58 197.6 0.0 2.2 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 GAO88060.1 - 0.01 15.4 0.2 0.03 13.9 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme Fungal_trans PF04082.13 GAO88061.1 - 7.9e-20 70.8 0.0 1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S15 PF02129.13 GAO88062.1 - 5.2e-42 144.1 1.7 1.2e-39 136.4 0.3 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAO88062.1 - 3.5e-24 85.9 0.0 4.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAO88062.1 - 0.0017 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO88062.1 - 0.039 12.4 0.1 5.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4243 PF14027.1 GAO88063.1 - 1.8e-93 313.5 0.1 2.2e-93 313.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DAO PF01266.19 GAO88064.1 - 7.7e-57 192.8 0.2 8.8e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO88064.1 - 7.9e-07 29.1 1.4 0.00012 22.0 0.9 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO88064.1 - 2.4e-05 24.6 0.2 0.00024 21.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO88064.1 - 4.2e-05 22.5 1.0 0.013 14.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO88064.1 - 5.6e-05 23.0 0.3 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 GAO88064.1 - 0.00015 21.7 0.5 0.0038 17.2 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 GAO88064.1 - 0.00099 17.6 0.4 0.33 9.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 GAO88064.1 - 0.0012 17.5 0.4 0.13 10.8 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 GAO88064.1 - 0.0018 17.2 0.6 0.11 11.3 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAO88064.1 - 0.0024 17.9 0.6 0.11 12.5 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88064.1 - 0.0088 15.8 1.6 1.2 8.9 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAO88064.1 - 0.011 14.8 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAO88064.1 - 0.016 14.8 0.1 0.081 12.5 0.0 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAO88064.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 GAO88064.1 - 0.029 13.7 0.1 0.058 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAO88064.1 - 0.038 12.8 0.3 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 GAO88064.1 - 0.048 12.7 0.5 0.19 10.8 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 GAO88064.1 - 0.067 11.3 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) PAN_1 PF00024.21 GAO88065.1 - 0.0013 18.4 12.4 0.011 15.4 0.2 3.0 2 1 1 3 3 3 2 PAN domain PAN_4 PF14295.1 GAO88065.1 - 0.0017 18.0 13.4 0.054 13.2 1.7 2.8 3 0 0 3 3 3 2 PAN domain ParA PF10609.4 GAO88066.1 - 1.1e-33 114.8 0.0 2.4e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAO88066.1 - 2.3e-16 59.7 0.0 3.3e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAO88066.1 - 2.4e-09 37.2 0.0 1.3e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 GAO88066.1 - 5.6e-06 25.6 0.1 8.8e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 GAO88066.1 - 0.00011 21.4 0.2 0.001 18.1 0.3 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 GAO88066.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 GAO88066.1 - 0.047 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.13 GAO88066.1 - 0.05 12.7 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 GAO88066.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein Ribosomal_S27e PF01667.12 GAO88066.1 - 0.078 12.5 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 AATF-Che1 PF13339.1 GAO88067.1 - 7.3e-33 113.5 6.6 7.3e-33 113.5 4.6 3.5 4 1 1 5 5 5 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 GAO88067.1 - 2.6e-32 110.7 0.0 2.6e-32 110.7 0.0 2.8 3 1 1 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal Fungal_trans_2 PF11951.3 GAO88069.1 - 3.5e-11 42.3 2.4 5.4e-11 41.7 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88069.1 - 0.00043 20.1 1.6 0.00043 20.1 1.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nuc_deoxyrib_tr PF05014.10 GAO88070.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase GFO_IDH_MocA PF01408.17 GAO88073.1 - 1.4e-21 77.2 0.0 2.4e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO88073.1 - 6.5e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1793 PF08760.6 GAO88074.1 - 1.4e-52 177.9 0.0 3.6e-52 176.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF2433 PF10360.4 GAO88074.1 - 8.3e-51 171.7 0.0 1.4e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) GBA2_N PF12215.3 GAO88074.1 - 2e-05 23.9 0.6 6.9e-05 22.1 0.4 1.9 2 1 0 2 2 2 1 beta-Glucocerebrosidase 2 N terminal DUF2360 PF10152.4 GAO88074.1 - 0.0058 16.9 2.6 0.031 14.5 1.2 2.5 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 GAO88074.1 - 0.0061 16.4 0.0 0.022 14.5 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAO88074.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.5 GAO88075.1 - 2.3e-111 372.8 12.8 2.3e-111 372.8 8.8 2.5 2 1 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 GAO88075.1 - 3.8e-08 33.1 10.9 3.8e-08 33.1 7.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor MbeD_MobD PF04899.7 GAO88075.1 - 0.014 15.2 2.2 0.038 13.8 1.5 1.7 1 0 0 1 1 1 0 MbeD/MobD like Adeno_PIX PF03955.9 GAO88075.1 - 0.024 15.1 1.7 0.079 13.4 0.5 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) EMP24_GP25L PF01105.19 GAO88075.1 - 0.076 12.7 0.5 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.6 GAO88075.1 - 0.18 11.7 0.8 0.38 10.6 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_Maf PF03131.12 GAO88075.1 - 0.3 11.3 15.2 0.042 14.1 7.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4537 PF15057.1 GAO88076.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.19 GAO88076.1 - 0.026 14.3 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Tudor domain Fis1_TPR_C PF14853.1 GAO88076.1 - 0.076 12.9 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat NAD_binding_10 PF13460.1 GAO88077.1 - 1.5e-05 25.0 0.0 4.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO88077.1 - 0.00046 19.5 0.0 0.0018 17.6 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 GAO88078.1 - 9.5e-20 71.3 0.0 1.2e-19 71.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO88078.1 - 1.2e-19 70.8 1.0 1.4e-19 70.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88078.1 - 1.5e-11 44.2 0.5 1.8e-11 43.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Patched PF02460.13 GAO88079.1 - 2.6e-81 273.7 14.2 9.4e-81 271.9 9.9 1.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 GAO88079.1 - 1.3e-51 174.1 7.4 1.3e-51 174.1 5.2 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 GAO88079.1 - 3e-07 29.4 9.7 3e-07 29.4 6.8 3.0 3 1 0 3 3 3 1 MMPL family HEAT PF02985.17 GAO88080.1 - 1.5e-19 68.2 7.5 5.3e-05 22.9 0.1 10.4 12 0 0 12 12 10 3 HEAT repeat HEAT_2 PF13646.1 GAO88080.1 - 1.8e-19 69.8 11.5 1.6e-06 28.2 0.1 7.5 6 3 2 8 8 7 5 HEAT repeats HEAT_EZ PF13513.1 GAO88080.1 - 2.9e-19 68.9 4.1 3.4e-05 24.2 0.0 10.3 10 2 3 13 13 13 5 HEAT-like repeat Cnd1 PF12717.2 GAO88080.1 - 8.7e-11 41.9 0.5 0.0014 18.5 0.2 4.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 GAO88080.1 - 2.7e-10 40.0 0.4 1e-08 34.9 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 GAO88080.1 - 5.3e-09 36.3 0.2 0.43 10.9 0.0 6.1 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 GAO88080.1 - 1.4e-05 24.0 3.9 0.009 14.7 0.0 4.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 GAO88080.1 - 1.7e-05 24.2 0.0 0.19 11.0 0.0 3.4 2 1 0 2 2 2 2 CLASP N terminal Arm PF00514.18 GAO88080.1 - 0.0011 18.6 0.2 39 4.2 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat UME PF08064.8 GAO88080.1 - 0.002 18.0 0.0 5 7.1 0.0 4.5 4 2 1 5 5 4 1 UME (NUC010) domain DUF577 PF04510.7 GAO88080.1 - 0.0034 17.1 0.1 0.036 13.7 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF577) Adaptin_N PF01602.15 GAO88080.1 - 0.0041 15.5 2.0 0.76 8.0 0.0 3.4 3 1 0 3 3 3 1 Adaptin N terminal region ParcG PF10274.4 GAO88080.1 - 0.011 15.6 0.3 0.41 10.5 0.1 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein DUF4042 PF13251.1 GAO88080.1 - 0.063 12.7 0.1 0.5 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) Fungal_trans PF04082.13 GAO88081.1 - 6.6e-13 48.1 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med7 PF05983.6 GAO88082.1 - 2.3e-60 203.0 1.2 3.1e-60 202.6 0.8 1.1 1 0 0 1 1 1 1 MED7 protein Hemerythrin PF01814.18 GAO88082.1 - 0.0045 17.1 0.4 0.0078 16.3 0.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PAP2 PF01569.16 GAO88083.1 - 1.2e-22 79.9 0.8 1.2e-22 79.9 0.5 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF4118 PF13493.1 GAO88083.1 - 1.1 9.5 4.9 0.3 11.3 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) DAO PF01266.19 GAO88084.1 - 2.2e-55 188.0 0.0 3.2e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 GAO88084.1 - 0.00016 21.5 0.3 0.00067 19.4 0.0 2.1 2 1 0 2 2 2 1 ThiF family FAD_binding_2 PF00890.19 GAO88084.1 - 0.00018 20.4 0.5 0.00083 18.3 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAO88084.1 - 0.00062 19.8 0.0 0.0077 16.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO88084.1 - 0.00065 19.6 0.1 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO88084.1 - 0.0016 18.2 0.2 0.028 14.1 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 GAO88084.1 - 0.0049 15.7 0.2 7.5 5.2 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAO88084.1 - 0.014 15.2 0.0 0.26 11.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAO88084.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAO88084.1 - 0.03 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO88084.1 - 0.051 13.2 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 GAO88084.1 - 0.067 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 GAO88084.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 GAO88084.1 - 0.12 12.7 0.0 2 8.9 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.10 GAO88085.1 - 4.9e-164 547.1 52.0 3.3e-163 544.4 31.3 2.1 2 0 0 2 2 2 2 OPT oligopeptide transporter protein Fungal_trans_2 PF11951.3 GAO88085.1 - 2.7e-81 273.1 1.5 5.1e-81 272.2 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88085.1 - 1.6e-06 27.8 8.5 3.1e-06 26.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-actin_cap_A PF01267.12 GAO88086.1 - 8.6e-96 320.1 0.0 1.1e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.9 GAO88087.1 - 6.5e-36 123.6 0.0 7.4e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3431 PF11913.3 GAO88088.1 - 1.8e-87 292.4 0.0 2.4e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DivIC PF04977.10 GAO88088.1 - 0.0057 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Septum formation initiator SET PF00856.23 GAO88089.1 - 0.0018 18.6 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 SET domain 2-Hacid_dh_C PF02826.14 GAO88090.1 - 6.3e-45 152.5 0.0 9.8e-45 151.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO88090.1 - 7.5e-09 35.1 0.0 9.5e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MFS_1 PF07690.11 GAO88091.1 - 2.4e-17 62.6 78.5 3.5e-14 52.2 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 GAO88092.1 - 4.2e-13 48.9 0.0 1.1e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO88092.1 - 6.6e-07 29.0 0.1 5.5e-06 26.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO88092.1 - 0.00026 21.8 0.0 0.0063 17.4 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF4233 PF14017.1 GAO88093.1 - 2.5 8.0 7.7 1 9.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) HET PF06985.6 GAO88094.1 - 0.033 14.3 0.1 0.75 9.9 0.1 2.4 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Glyco_hydro_25 PF01183.15 GAO88095.1 - 8.2e-42 143.0 2.6 9.5e-42 142.8 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Fungal_trans PF04082.13 GAO88096.1 - 3.4e-25 88.3 0.0 5.7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88096.1 - 1.8e-09 37.3 9.5 2.8e-09 36.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 GAO88097.1 - 1.8e-31 110.0 0.0 2.5e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAO88097.1 - 3.5e-10 39.6 4.2 7e-07 28.7 0.0 3.4 2 2 1 4 4 4 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAO88097.1 - 7.9e-07 29.3 0.4 1.1e-05 25.6 0.3 2.2 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 GAO88097.1 - 3.7e-05 22.8 0.0 0.00021 20.2 0.0 1.9 1 1 1 2 2 2 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 GAO88097.1 - 0.00022 20.9 0.0 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase OPT PF03169.10 GAO88098.1 - 1.3e-167 559.0 58.2 1.5e-167 558.8 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.19 GAO88099.1 - 3.7e-21 75.4 0.1 1.3e-19 70.3 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF604 PF04646.7 GAO88099.1 - 0.015 14.5 0.2 0.025 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 NAD_binding_8 PF13450.1 GAO88099.1 - 0.019 14.9 0.7 0.046 13.7 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO88099.1 - 0.065 13.0 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAO88099.1 - 0.066 13.3 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 GAO88099.1 - 0.069 12.9 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 GAO88099.1 - 0.081 12.3 0.4 0.33 10.3 0.6 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAO88099.1 - 0.17 11.4 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Response_reg PF00072.19 GAO88100.1 - 1.5e-24 86.1 0.2 3.3e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAO88100.1 - 1.9e-24 85.5 0.0 3.8e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 GAO88100.1 - 1.2e-19 70.6 0.0 4.6e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 GAO88100.1 - 1.2e-18 66.8 0.1 2.7e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 GAO88100.1 - 3.2e-13 49.4 0.0 6.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 GAO88100.1 - 4.6e-10 39.5 0.0 0.0001 22.3 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 GAO88100.1 - 0.0055 16.5 0.0 6.5 6.7 0.0 3.3 3 0 0 3 3 3 2 PAS domain Pro-kuma_activ PF09286.6 GAO88101.1 - 1.1e-48 164.8 0.1 1.9e-48 164.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAO88101.1 - 5e-05 22.6 0.0 8.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Aldo_ket_red PF00248.16 GAO88102.1 - 4.5e-47 160.2 0.0 5.5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NeuB PF03102.9 GAO88102.1 - 0.097 11.7 0.0 1.1 8.3 0.0 2.1 1 1 1 2 2 2 0 NeuB family RimK PF08443.6 GAO88103.1 - 0.00015 21.3 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain VRP1 PF03538.9 GAO88103.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein HET PF06985.6 GAO88105.1 - 2.7e-21 76.1 0.0 6e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chorismate_bind PF00425.13 GAO88106.1 - 5.6e-52 176.6 0.0 7.5e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme 3Beta_HSD PF01073.14 GAO88109.1 - 1.1e-18 66.9 0.0 2.7e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO88109.1 - 6.7e-17 61.7 0.4 1.7e-16 60.3 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO88109.1 - 3.2e-12 46.8 0.3 7.8e-12 45.5 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO88109.1 - 9.8e-11 41.0 0.0 3.5e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAO88109.1 - 1.5e-07 30.9 1.2 3.1e-07 29.8 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAO88109.1 - 1.7e-07 30.4 0.1 2.5e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAO88109.1 - 5.6e-07 29.6 1.4 5.6e-07 29.6 1.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAO88109.1 - 0.00026 20.6 0.4 0.00095 18.8 0.4 1.8 2 0 0 2 2 2 1 KR domain Fibrillarin PF01269.12 GAO88109.1 - 0.0014 17.5 0.1 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 Fibrillarin RmlD_sub_bind PF04321.12 GAO88109.1 - 0.018 13.9 0.1 0.05 12.4 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain COesterase PF00135.23 GAO88110.1 - 7.4e-73 246.0 0.0 1.1e-72 245.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO88110.1 - 2.2e-06 27.3 0.3 1e-05 25.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO88110.1 - 0.0079 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 GAO88110.1 - 0.092 11.3 0.0 0.36 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) NmrA PF05368.8 GAO88111.1 - 7.9e-11 41.6 0.0 9.4e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Helitron_like_N PF14214.1 GAO88114.1 - 1.6e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 GAO88115.1 - 1.4e-05 24.7 0.1 3.8e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 GAO88115.1 - 0.00011 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 GAO88115.1 - 0.00024 20.7 0.5 0.00047 19.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain AATase PF07247.7 GAO88116.1 - 1.7e-21 76.3 0.0 2.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 GAO88116.1 - 0.00055 19.5 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF4211 PF13926.1 GAO88116.1 - 0.061 12.7 0.1 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) ABC_tran PF00005.22 GAO88117.1 - 2.2e-44 151.1 0.0 7.2e-22 78.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO88117.1 - 5.2e-21 75.2 21.4 8.6e-21 74.5 4.4 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAO88117.1 - 6.2e-12 46.0 0.0 0.0052 16.7 0.0 4.4 2 2 1 4 4 4 3 AAA domain GST_N PF02798.15 GAO88117.1 - 4.4e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SMC_N PF02463.14 GAO88117.1 - 3e-06 26.6 0.1 1.6 7.8 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAO88117.1 - 6.9e-06 26.8 0.0 0.065 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO88117.1 - 6.1e-05 23.1 0.0 0.28 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO88117.1 - 6.3e-05 23.2 0.5 0.15 12.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 GAO88117.1 - 0.00012 21.5 4.3 0.09 12.3 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain MobB PF03205.9 GAO88117.1 - 0.00025 20.7 0.2 0.51 10.0 0.0 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAO88117.1 - 0.00037 20.3 0.0 0.042 13.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO88117.1 - 0.003 17.0 0.2 1.2 8.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 GAO88117.1 - 0.003 17.4 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 GAO88117.1 - 0.0033 17.7 0.0 1.9 8.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAO88117.1 - 0.0033 16.8 1.1 0.38 10.1 0.0 2.9 3 1 0 3 3 3 1 AAA-like domain T2SE PF00437.15 GAO88117.1 - 0.0042 16.0 0.0 0.44 9.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAO88117.1 - 0.0055 16.7 0.7 5.6 6.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 GAO88117.1 - 0.0056 15.8 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 GAO88117.1 - 0.0056 16.1 0.0 0.069 12.6 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 GAO88117.1 - 0.0069 16.8 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 GAO88117.1 - 0.019 14.7 0.1 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 GAO88117.1 - 0.02 14.7 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family GST_N_3 PF13417.1 GAO88117.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PduV-EutP PF10662.4 GAO88117.1 - 0.18 11.2 0.1 0.71 9.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 GAO88117.1 - 0.2 11.2 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 GAO88117.1 - 0.28 10.2 0.0 21 4.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TauD PF02668.11 GAO88118.1 - 1.5e-46 159.2 0.0 1.8e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.23 GAO88119.1 - 1.5e-164 547.4 0.0 1.4e-85 287.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAO88119.1 - 1.3e-80 270.5 1.2 3.8e-43 147.4 0.1 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 GAO88119.1 - 2.7e-23 82.0 0.0 4.4e-10 39.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site SfsA PF03749.8 GAO88119.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sugar fermentation stimulation protein Abhydrolase_3 PF07859.8 GAO88120.1 - 6.8e-28 97.6 0.2 1.3e-27 96.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO88120.1 - 4.5e-08 32.1 0.0 8.1e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) LIP PF03583.9 GAO88122.1 - 1.6e-53 181.8 0.1 2.1e-53 181.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 GAO88122.1 - 0.00017 21.3 0.0 0.00041 20.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ABM PF03992.11 GAO88123.1 - 4.6e-05 23.3 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.11 GAO88126.1 - 7.3e-20 70.9 43.4 7.3e-20 70.9 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.13 GAO88127.1 - 1.7e-11 43.5 16.1 6e-11 41.8 11.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 GAO88127.1 - 3.1e-07 29.8 0.2 5.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO88127.1 - 9e-05 22.2 0.1 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAO88127.1 - 0.00015 21.3 0.0 0.00038 19.9 0.0 1.6 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAO88127.1 - 0.00015 21.6 0.1 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAO88127.1 - 0.00037 19.9 2.9 0.0022 17.4 2.0 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 GAO88127.1 - 0.0004 19.6 0.0 0.00082 18.6 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.7 GAO88127.1 - 0.12 10.8 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 GAO88127.1 - 0.18 11.3 3.2 0.12 11.9 0.6 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1496 PF07383.7 GAO88127.1 - 1.9 7.8 5.5 26 4.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1496) Glyco_hydro_10 PF00331.15 GAO88128.1 - 1.1e-73 248.0 1.0 1.2e-73 247.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 GAO88128.1 - 0.0085 16.5 0.0 0.043 14.2 0.0 2.1 2 1 0 2 2 2 1 Sugar-binding cellulase-like LysM PF01476.15 GAO88129.1 - 6.2e-30 102.8 0.3 8.2e-06 25.6 0.1 5.5 5 0 0 5 5 5 5 LysM domain Glyco_hydro_18 PF00704.23 GAO88130.1 - 2.6e-76 257.3 1.6 3.7e-76 256.8 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAO88130.1 - 2.6e-08 33.6 7.8 2.6e-08 33.6 5.4 5.1 6 0 0 6 6 6 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 GAO88130.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF2622 PF11080.3 GAO88130.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Ank_4 PF13637.1 GAO88131.1 - 1.3e-16 60.6 2.6 0.0026 18.2 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO88131.1 - 3.6e-15 56.0 0.0 0.00051 20.3 0.3 4.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO88131.1 - 1.9e-08 33.7 6.7 1.1 9.7 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 GAO88131.1 - 2.3e-08 34.0 10.6 0.15 12.3 0.0 6.2 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAO88131.1 - 8.7e-06 25.3 17.2 0.39 10.6 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Glyco_hydro_16 PF00722.16 GAO88133.1 - 2.8e-20 72.3 0.2 8.7e-20 70.7 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAO88133.1 - 7.6e-06 24.3 3.0 0.011 13.9 0.0 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_3 PF13385.1 GAO88133.1 - 0.38 10.9 10.7 0.02 15.1 1.5 2.5 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Peptidase_S9 PF00326.16 GAO88134.1 - 3.9e-34 117.7 0.0 6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO88134.1 - 9.7e-06 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO88134.1 - 0.15 10.4 0.0 0.3 9.5 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_GDSL_2 PF13472.1 GAO88135.1 - 0.003 17.7 0.0 0.0065 16.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3431 PF11913.3 GAO88136.1 - 9.2e-80 267.2 0.0 1.1e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Recep_L_domain PF01030.19 GAO88137.1 - 2.9e-09 36.8 0.2 4.2e-06 26.7 0.2 2.7 1 1 1 2 2 2 2 Receptor L domain VSP PF03302.8 GAO88137.1 - 3.2e-08 32.6 0.1 3.2e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.5 GAO88137.1 - 0.0016 17.6 0.5 0.0033 16.7 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 GAO88137.1 - 0.0038 16.9 0.6 0.0063 16.2 0.4 1.5 1 1 0 1 1 1 1 Rifin/stevor family Adeno_E3_CR2 PF02439.10 GAO88137.1 - 0.0047 16.4 0.2 0.0083 15.6 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Rax2 PF12768.2 GAO88137.1 - 0.0088 15.2 1.5 0.016 14.4 1.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF912 PF06024.7 GAO88137.1 - 0.011 15.8 0.0 0.07 13.1 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ODV-E18 PF10717.4 GAO88137.1 - 0.018 14.4 0.2 0.053 12.9 0.1 1.9 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4381 PF14316.1 GAO88137.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM51 PF15345.1 GAO88137.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Cytochrom_B_N PF00033.14 GAO88137.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF4083 PF13314.1 GAO88137.1 - 0.025 14.4 0.3 0.051 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4448 PF14610.1 GAO88137.1 - 0.025 14.0 0.0 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.1 GAO88137.1 - 0.03 14.5 0.7 0.091 12.9 0.0 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 GAO88137.1 - 0.033 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OSTMP1 PF09777.4 GAO88137.1 - 0.035 13.2 0.1 0.059 12.5 0.1 1.4 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor MSC PF09402.5 GAO88137.1 - 0.053 12.2 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PgaD PF13994.1 GAO88137.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein ASFV_J13L PF05568.6 GAO88137.1 - 0.1 12.1 1.3 0.11 12.0 0.0 1.8 2 1 0 2 2 1 0 African swine fever virus J13L protein OAD_gamma PF04277.8 GAO88137.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FixQ PF05545.6 GAO88137.1 - 0.16 11.6 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RCR PF12273.3 GAO88137.1 - 0.68 10.4 7.1 0.29 11.6 3.0 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ecm33 PF12454.3 GAO88137.1 - 4 7.3 5.4 1.7 8.5 1.0 2.5 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Thioredoxin PF00085.15 GAO88138.1 - 2.9e-26 91.1 0.0 3.5e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAO88138.1 - 3.8e-08 33.3 0.0 1.1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAO88138.1 - 2.9e-06 27.4 0.1 1.9e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 GAO88138.1 - 8.4e-05 22.1 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 GAO88138.1 - 0.00014 21.4 0.2 0.00068 19.2 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 GAO88138.1 - 0.0039 17.1 0.0 0.0083 16.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 GAO88138.1 - 0.0079 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 GAO88138.1 - 0.016 14.7 0.0 0.16 11.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Phosducin PF02114.11 GAO88138.1 - 0.048 12.3 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosducin WD40 PF00400.27 GAO88139.1 - 1.4e-25 88.1 7.5 6.8e-10 38.4 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAO88139.1 - 2e-19 69.2 0.0 7.1e-19 67.4 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Fungal_trans_2 PF11951.3 GAO88139.1 - 1.2e-08 33.9 3.4 1.8e-08 33.4 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.17 GAO88140.1 - 2.3e-31 108.3 0.2 3.1e-31 107.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO88140.1 - 2.3e-20 73.2 0.1 7.9e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAO88140.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAO88140.1 - 3.9e-05 22.8 0.2 5.2e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pex14_N PF04695.8 GAO88140.1 - 0.0067 16.4 3.5 0.012 15.6 2.4 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR_HSR1 PF01926.18 GAO88140.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 GAO88140.1 - 0.097 11.3 7.4 0.2 10.2 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 GAO88140.1 - 0.13 10.9 0.3 3 6.3 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Transglut_core PF01841.14 GAO88141.1 - 3e-11 43.5 0.0 5.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 GAO88141.1 - 0.042 13.1 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like domain HpcH_HpaI PF03328.9 GAO88142.1 - 1.2e-29 102.7 0.1 2.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.13 GAO88142.1 - 3.9e-22 78.3 1.9 6.3e-22 77.6 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_6 PF03737.10 GAO88143.1 - 6.2e-41 139.8 11.6 8.4e-24 84.1 3.1 2.1 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase Aminotran_1_2 PF00155.16 GAO88144.1 - 6.7e-74 249.0 0.0 7.6e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 GAO88145.1 - 1.3e-26 93.9 0.0 1.5e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO88145.1 - 4.4e-14 52.5 0.1 5.7e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO88145.1 - 1.3e-11 44.4 0.0 1.4e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 GAO88145.1 - 0.00011 21.4 0.0 0.0021 17.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 GAO88145.1 - 0.00037 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 GAO88145.1 - 0.0068 16.0 0.4 0.015 14.9 0.3 1.6 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 GAO88145.1 - 0.0072 14.8 0.0 0.84 8.0 0.0 2.1 2 0 0 2 2 2 2 Ndr family Hydrolase_4 PF12146.3 GAO88145.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 GAO88145.1 - 0.013 15.7 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 GAO88145.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 GAO88145.1 - 0.029 14.1 0.2 0.072 12.8 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.6 GAO88145.1 - 0.11 11.2 0.1 0.41 9.4 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase DUF2435 PF10363.4 GAO88146.1 - 8.9e-28 96.0 0.3 2.5e-26 91.4 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 GAO88146.1 - 2.2e-11 42.9 0.0 5.1e-10 38.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 GAO88146.1 - 0.026 14.8 0.1 0.99 9.7 0.0 3.5 4 0 0 4 4 4 0 HEAT repeats M16C_assoc PF08367.6 GAO88146.1 - 0.08 11.7 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase M16C associated DBR1 PF05011.8 GAO88147.1 - 1e-51 174.6 0.1 3.3e-51 172.9 0.1 1.9 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 GAO88147.1 - 0.00045 19.6 0.8 0.00088 18.7 0.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TIP120 PF08623.5 GAO88148.1 - 5.4e-65 218.0 0.2 1.2e-63 213.6 0.0 3.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 GAO88148.1 - 7.4e-10 38.0 8.8 0.078 13.0 0.0 9.3 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 GAO88148.1 - 1.8e-08 34.5 13.2 0.25 11.6 0.0 7.3 6 2 2 8 8 8 4 HEAT repeats Arm PF00514.18 GAO88148.1 - 0.00032 20.4 0.6 3.7 7.5 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAO88148.1 - 0.0017 18.7 18.2 1.5 9.4 0.0 9.9 10 2 1 11 11 11 1 HEAT-like repeat Adaptin_N PF01602.15 GAO88148.1 - 0.015 13.6 1.3 9.9 4.3 0.1 4.7 4 2 0 4 4 4 0 Adaptin N terminal region DUF1546 PF07571.8 GAO88148.1 - 0.029 14.4 0.0 1.5 9.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) CLASP_N PF12348.3 GAO88148.1 - 0.076 12.3 0.4 9.6 5.4 0.0 3.4 3 0 0 3 3 3 0 CLASP N terminal LRR_4 PF12799.2 GAO88149.1 - 1.6e-25 88.1 50.9 6.5e-07 28.8 2.2 9.6 5 1 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO88149.1 - 6.9e-22 76.9 46.3 3.4e-07 29.9 4.5 6.8 4 1 5 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 GAO88149.1 - 8.9e-10 37.2 45.5 0.14 12.3 0.4 12.4 11 3 2 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 GAO88149.1 - 1.1e-05 25.0 17.6 0.026 14.1 1.0 4.5 2 1 3 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.1 GAO88149.1 - 3.8e-05 23.3 39.8 0.2 11.8 0.1 10.0 8 3 2 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 GAO88149.1 - 0.0014 18.4 46.2 0.67 10.3 0.2 11.5 11 1 1 12 12 12 4 Leucine rich repeat Clathrin PF00637.15 GAO88151.1 - 2.5e-23 82.2 3.0 3.5e-20 72.0 2.5 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 GAO88151.1 - 2.7e-20 71.9 0.1 6.2e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 GAO88151.1 - 0.0017 18.0 5.8 0.0032 17.1 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_14 PF13428.1 GAO88151.1 - 0.0024 18.3 0.0 0.41 11.4 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 GAO88151.1 - 0.0031 17.3 6.2 0.0061 16.3 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO88151.1 - 0.0033 17.4 2.9 0.0064 16.5 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAO88151.1 - 0.0058 16.4 1.8 0.013 15.3 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 GAO88151.1 - 0.0069 16.3 5.7 0.014 15.3 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 GAO88151.1 - 0.0072 15.9 0.9 0.023 14.3 0.1 2.3 2 0 0 2 2 2 1 TPR repeat zf-C3HC4_3 PF13920.1 GAO88151.1 - 0.013 15.1 4.9 0.024 14.2 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 GAO88151.1 - 0.05 13.4 0.5 0.05 13.4 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Flavodoxin_5 PF12724.2 GAO88151.1 - 0.071 13.1 0.0 0.51 10.3 0.0 2.4 3 0 0 3 3 3 0 Flavodoxin domain TPR_12 PF13424.1 GAO88151.1 - 0.12 12.3 8.5 0.23 11.4 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 GAO88151.1 - 0.14 11.8 6.0 0.27 10.9 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 GAO88151.1 - 0.74 9.8 6.0 0.14 12.1 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAO88151.1 - 1.8 8.7 11.5 11 6.2 0.3 4.0 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Polysacc_deac_1 PF01522.16 GAO88153.1 - 1.6e-30 105.3 0.0 5.2e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 GAO88153.1 - 0.5 10.3 44.7 0.29 11.1 2.3 3.5 3 0 0 3 3 3 0 Chitin recognition protein HEAT_2 PF13646.1 GAO88154.1 - 4.3e-05 23.7 0.6 0.00012 22.2 0.1 2.0 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 GAO88154.1 - 6e-05 22.7 0.7 0.04 13.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Cnd3 PF12719.2 GAO88154.1 - 0.02 13.8 0.1 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Vac14_Fab1_bd PF12755.2 GAO88154.1 - 0.073 13.4 0.0 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAO88154.1 - 0.12 12.8 6.8 0.48 10.9 0.1 4.5 4 2 2 6 6 6 0 HEAT-like repeat TRAM_LAG1_CLN8 PF03798.11 GAO88156.1 - 8.6e-35 120.0 20.5 1.4e-34 119.3 14.2 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 GAO88156.1 - 1.5e-23 82.0 0.6 6.3e-23 80.0 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein zf-ZPR1 PF03367.8 GAO88157.1 - 1.7e-100 332.9 0.1 1.9e-49 166.9 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 GAO88157.1 - 0.21 11.2 2.0 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 GAO88157.1 - 2.9 7.6 11.7 2.2 8.0 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 GAO88157.1 - 9.4 6.1 8.5 13 5.7 0.3 3.1 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Pro_isomerase PF00160.16 GAO88158.1 - 4.6e-36 124.3 0.0 5.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC6 PF05460.8 GAO88159.1 - 7.7e-109 364.0 0.0 8.8e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Telomere_reg-2 PF10193.4 GAO88159.1 - 0.039 14.2 0.1 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Telomere length regulation protein DUF2419 PF10343.4 GAO88160.1 - 4.1e-148 492.2 0.0 4.9e-148 492.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 GAO88161.1 - 2.6e-42 143.8 0.2 6.7e-42 142.5 0.0 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 GAO88161.1 - 2.8e-29 100.4 1.2 9.2e-29 98.8 0.2 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 GAO88161.1 - 9e-23 80.1 0.1 2.4e-22 78.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 GAO88161.1 - 2.7e-21 74.6 9.1 6.6e-21 73.4 2.2 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 GAO88161.1 - 8.7e-05 22.7 0.0 0.00034 20.8 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAO88161.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAO88161.1 - 0.027 14.8 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAO88162.1 - 6.4e-29 101.0 0.6 1.6e-16 60.7 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88162.1 - 5e-13 49.3 0.6 1.3e-12 48.0 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88162.1 - 3e-12 46.5 2.0 7.7e-11 41.9 1.4 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO88162.1 - 6e-05 22.5 0.1 0.025 14.0 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 GAO88162.1 - 0.00081 19.7 0.3 0.0019 18.5 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAO88162.1 - 0.0021 18.1 0.1 0.075 13.1 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAO88162.1 - 0.0055 15.6 0.1 0.011 14.6 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Skp1_POZ PF03931.10 GAO88163.1 - 7.2e-11 42.0 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 GAO88164.1 - 9.6e-36 121.0 0.0 1.6e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 GAO88164.1 - 0.0028 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 GAO88165.1 - 5.4e-15 55.6 0.0 3e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DNA_pol_delta_4 PF04081.8 GAO88166.1 - 2.9e-29 101.8 1.1 4.6e-29 101.2 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF4452 PF14618.1 GAO88166.1 - 0.0063 16.3 1.7 0.0063 16.3 1.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) FRG1 PF06229.7 GAO88166.1 - 0.055 12.9 0.6 0.075 12.4 0.4 1.3 1 0 0 1 1 1 0 FRG1-like family M16C_assoc PF08367.6 GAO88166.1 - 0.21 10.3 1.9 0.29 9.9 1.3 1.2 1 0 0 1 1 1 0 Peptidase M16C associated CFEM PF05730.6 GAO88167.1 - 1.3e-16 60.1 11.8 3.5e-16 58.7 8.2 1.7 1 0 0 1 1 1 1 CFEM domain NPR3 PF03666.8 GAO88167.1 - 0.71 8.3 7.2 0.94 7.9 5.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF966 PF06136.8 GAO88167.1 - 0.81 9.0 15.1 0.96 8.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 GAO88167.1 - 1.2 8.2 4.3 1.6 7.8 3.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.12 GAO88167.1 - 1.6 8.4 9.3 2 8.1 6.4 1.2 1 0 0 1 1 1 0 DDHD domain ThiF PF00899.16 GAO88169.1 - 3.7e-06 26.7 0.0 9.4e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.9 GAO88170.1 - 2.5e-39 134.3 0.0 2.3e-35 121.4 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 GAO88170.1 - 0.0025 17.4 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain WD40 PF00400.27 GAO88171.1 - 5.4e-22 76.8 7.3 8.4e-06 25.4 1.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat SGL PF08450.7 GAO88171.1 - 0.011 15.0 0.1 0.079 12.3 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region ATP_bind_1 PF03029.12 GAO88172.1 - 8.7e-75 251.3 0.0 1.1e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAO88172.1 - 0.00038 21.2 1.8 0.001 19.8 0.2 2.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 GAO88172.1 - 0.0011 17.8 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 GAO88172.1 - 0.0021 17.5 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 GAO88172.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAO88172.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 GAO88172.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 GAO88172.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 GAO88172.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAO88172.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 GAO88172.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Fer4_NifH PF00142.13 GAO88172.1 - 0.24 10.5 0.5 1.4 7.9 0.3 2.0 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNase_P_Rpp14 PF01900.14 GAO88173.1 - 7.5e-39 131.9 0.0 9.8e-39 131.5 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 GAO88174.1 - 2.2e-19 69.4 0.0 7.2e-17 61.1 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 GAO88174.1 - 5.1e-19 68.5 0.0 1.9e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAO88174.1 - 3.3e-16 59.2 0.1 5.6e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAO88174.1 - 1.1e-06 28.3 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 GAO88175.1 - 2.9e-09 36.6 0.0 4.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain zf-RING_5 PF14634.1 GAO88176.1 - 3.4e-08 33.0 7.7 6.3e-08 32.2 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAO88176.1 - 3.4e-05 23.7 4.7 6.7e-05 22.8 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO88176.1 - 0.00044 19.8 7.3 0.00089 18.8 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO88176.1 - 0.00057 19.6 5.3 0.00057 19.6 3.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAO88176.1 - 0.0029 17.2 6.8 0.0055 16.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAO88176.1 - 0.047 13.5 2.8 0.11 12.3 2.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAO88176.1 - 0.08 12.7 4.7 0.19 11.5 3.2 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein TMF_TATA_bd PF12325.3 GAO88176.1 - 0.085 12.5 5.1 0.11 12.1 2.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 GAO88176.1 - 0.087 12.9 3.2 0.16 12.0 2.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAO88176.1 - 0.22 11.1 1.9 0.37 10.3 1.3 1.3 1 0 0 1 1 1 0 IncA protein zf-RING_UBOX PF13445.1 GAO88176.1 - 0.35 10.6 3.8 0.72 9.6 2.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TMF_DNA_bd PF12329.3 GAO88176.1 - 0.71 9.7 5.9 0.25 11.1 2.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding XAP5 PF04921.9 GAO88177.1 - 1.3e-85 286.8 0.0 4.3e-85 285.1 0.0 1.7 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.1 GAO88177.1 - 0.014 15.5 6.1 0.032 14.4 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fip1 PF05182.8 GAO88178.1 - 9.3e-22 76.0 1.9 1.6e-21 75.2 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.16 GAO88179.1 - 3.1e-28 97.5 0.0 3.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TauD PF02668.11 GAO88181.1 - 1.5e-51 175.5 0.6 2.3e-51 174.9 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.1 GAO88182.1 - 9.1e-09 35.5 95.1 4.6e-06 26.8 36.1 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region Asp_Glu_race_2 PF14669.1 GAO88182.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative aspartate racemase WD40 PF00400.27 GAO88183.1 - 3.2e-06 26.7 4.3 17 5.4 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat Lactonase PF10282.4 GAO88183.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.1 GAO88185.1 - 6.5e-15 55.7 0.0 3.8e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO88185.1 - 4.6e-05 23.0 0.0 0.00018 21.1 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAO88185.1 - 4.7e-05 23.9 0.0 0.001 19.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 GAO88185.1 - 0.011 15.2 0.0 0.063 12.7 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_11 PF13414.1 GAO88186.1 - 3.5e-12 45.7 3.5 8.9e-12 44.4 1.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 GAO88186.1 - 3.8e-05 23.5 0.9 3.8e-05 23.5 0.6 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO88186.1 - 0.00033 20.1 4.8 0.5 10.0 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAO88186.1 - 0.0092 15.8 4.1 1.6 8.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO88186.1 - 0.017 14.9 0.3 5.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO88186.1 - 0.029 14.6 0.8 0.2 12.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAO88186.1 - 0.052 13.6 0.4 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAO88186.1 - 0.087 12.6 1.3 10 6.0 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Ca_hom_mod PF14798.1 GAO88186.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator TPR_14 PF13428.1 GAO88186.1 - 4.1 8.3 6.3 17 6.3 0.0 4.2 4 2 2 6 6 6 0 Tetratricopeptide repeat COesterase PF00135.23 GAO88187.1 - 2.5e-70 237.7 0.0 3.2e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.11 GAO88187.1 - 1.4e-42 145.6 20.6 8.7e-35 120.0 3.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 GAO88187.1 - 1.5e-08 34.4 0.0 1.3e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_2 PF13347.1 GAO88187.1 - 3e-06 25.9 4.6 3e-06 25.9 3.2 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein Abhydrolase_5 PF12695.2 GAO88187.1 - 0.00028 20.6 0.0 0.0008 19.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO88187.1 - 0.00083 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAO88187.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family ATG22 PF11700.3 GAO88187.1 - 0.025 13.0 8.8 0.062 11.7 6.1 1.7 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like COesterase PF00135.23 GAO88188.1 - 6.2e-65 219.9 0.0 2.5e-63 214.6 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO88188.1 - 8.2e-06 25.5 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO88188.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family HgmA PF04209.8 GAO88189.1 - 2.3e-151 504.0 0.0 2.6e-151 503.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase adh_short_C2 PF13561.1 GAO88190.1 - 4.6e-19 69.1 0.0 6.9e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO88190.1 - 2.5e-16 60.0 4.3 1e-14 54.7 3.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88190.1 - 3.6e-05 23.5 3.1 9.5e-05 22.1 0.1 2.3 1 1 0 2 2 2 1 KR domain Pyr_redox PF00070.22 GAO88190.1 - 0.0022 18.3 0.1 0.089 13.2 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 GAO88190.1 - 0.021 14.8 0.8 0.4 10.6 0.5 2.1 1 1 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 GAO88190.1 - 0.04 13.4 0.1 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Metallophos PF00149.23 GAO88191.1 - 7.4e-44 149.5 0.8 9.4e-44 149.2 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 GAO88192.1 - 2.3e-35 121.4 0.0 3.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 GAO88192.1 - 1.3e-16 60.9 16.1 1.3e-16 60.9 11.2 2.7 3 1 0 3 3 3 1 PI31 proteasome regulator Fungal_trans_2 PF11951.3 GAO88193.1 - 3.5e-40 137.8 1.1 3.7e-40 137.6 0.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 GAO88195.1 - 1.5e-30 106.3 1.3 3.4e-30 105.1 0.9 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 GAO88195.1 - 2e-20 72.3 0.1 4.9e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 GAO88195.1 - 7.4e-19 67.0 0.6 1.8e-18 65.7 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAO88195.1 - 6.8e-07 29.8 0.1 2.3e-06 28.1 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAO88195.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lantibiotic_a PF14867.1 GAO88195.1 - 0.72 9.1 6.9 1.3 8.2 4.8 1.5 1 0 0 1 1 1 0 Lantibiotic alpha UvdE PF03851.9 GAO88196.1 - 3.7e-112 373.8 0.0 5.1e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.4 GAO88196.1 - 5.5e-33 112.8 0.0 1.3e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Trypan_PARP PF05887.6 GAO88198.1 - 0.05 13.4 7.8 0.064 13.0 5.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 GAO88198.1 - 0.27 9.5 3.1 0.28 9.4 2.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MARVEL PF01284.18 GAO88199.1 - 0.00019 21.2 16.1 0.004 16.9 11.9 2.0 1 1 1 2 2 2 1 Membrane-associating domain RCR PF12273.3 GAO88199.1 - 0.006 17.1 0.1 0.006 17.1 0.0 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red GerA PF03323.8 GAO88199.1 - 0.18 9.9 0.1 0.3 9.1 0.1 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein ADH_zinc_N PF00107.21 GAO88200.1 - 7.4e-27 93.4 0.1 1.4e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO88200.1 - 1.4e-22 79.5 0.1 2.9e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO88200.1 - 9.4e-05 23.3 0.0 0.0002 22.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAO88200.1 - 0.00033 20.2 0.0 0.0013 18.3 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 GAO88200.1 - 0.021 14.9 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAO88200.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.12 GAO88200.1 - 0.027 14.8 0.1 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 GAO88200.1 - 0.16 12.4 1.5 1.6 9.1 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PGA2 PF07543.7 GAO88201.1 - 1.5e-51 173.8 4.9 2.2e-51 173.3 3.4 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 EcsC PF12787.2 GAO88201.1 - 0.037 13.4 1.5 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 EcsC protein family Selenoprotein_S PF06936.6 GAO88201.1 - 0.45 10.0 6.2 0.51 9.8 3.5 1.7 1 1 0 1 1 1 0 Selenoprotein S (SelS) DUF2681 PF10883.3 GAO88201.1 - 2.1 8.5 9.6 0.41 10.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) YtxH PF12732.2 GAO88201.1 - 3 8.2 6.6 4.6 7.6 2.3 2.3 2 0 0 2 2 2 0 YtxH-like protein SHR3_chaperone PF08229.6 GAO88201.1 - 9.7 5.0 7.2 0.96 8.3 0.1 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 MMS1_N PF10433.4 GAO88202.1 - 1.8e-99 333.2 0.0 2.6e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAO88202.1 - 3.3e-78 263.0 0.1 3.2e-76 256.4 0.0 3.3 4 0 0 4 4 4 1 CPSF A subunit region FAD_binding_1 PF00667.15 GAO88203.1 - 1e-62 211.4 0.0 1.5e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAO88203.1 - 3.8e-34 117.7 1.6 6.6e-34 116.9 1.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAO88203.1 - 1e-22 80.7 0.0 1.7e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAO88203.1 - 0.02 14.9 0.3 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.1 GAO88204.1 - 1.2e-230 766.9 0.0 2.6e-230 765.8 0.0 1.6 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 GAO88204.1 - 4.3e-97 324.9 0.0 1.5e-96 323.1 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 GAO88204.1 - 8.5e-37 126.3 9.4 9.2e-15 53.3 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region NAD_binding_11 PF14833.1 GAO88205.1 - 1.4e-31 109.1 0.0 2.4e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 GAO88205.1 - 3.1e-25 88.9 0.5 5e-25 88.2 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_1 PF00076.17 GAO88206.1 - 3.1e-21 74.7 0.1 1.9e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO88206.1 - 8.1e-16 57.7 0.0 3.8e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88206.1 - 0.011 15.5 2.0 0.47 10.3 0.1 2.8 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliG_N PF14842.1 GAO88206.1 - 0.031 14.3 0.3 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 FliG N-terminal domain PAPS_reduct PF01507.14 GAO88207.1 - 2.2e-26 92.7 0.0 2e-25 89.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DnaJ PF00226.26 GAO88208.1 - 2.5e-14 52.7 4.0 3.9e-14 52.1 1.0 2.6 3 0 0 3 3 3 1 DnaJ domain tRNA-synt_1e PF01406.14 GAO88208.1 - 0.11 11.5 1.0 0.13 11.4 0.7 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 GAO88209.1 - 7.2e-45 152.5 0.0 1.6e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 GAO88209.1 - 5.9e-26 89.7 0.3 1.9e-25 88.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAO88209.1 - 1.9e-22 78.9 0.0 9e-22 76.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO88209.1 - 0.016 14.0 0.0 0.039 12.7 0.0 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain AA_permease PF00324.16 GAO88210.1 - 7.3e-123 410.4 42.3 8.3e-123 410.2 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO88210.1 - 3.5e-40 137.8 49.4 4.4e-40 137.5 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 GAO88210.1 - 0.036 14.2 0.8 0.036 14.2 0.6 4.6 5 0 0 5 5 5 0 PrgI family protein AT_hook PF02178.14 GAO88211.1 - 0.068 12.8 3.1 0.62 9.9 0.2 3.0 2 0 0 2 2 2 0 AT hook motif DEAD PF00270.24 GAO88212.1 - 1.6e-44 151.3 0.1 4.8e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO88212.1 - 1.2e-21 76.3 0.1 3.8e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 GAO88212.1 - 1.3e-20 72.9 0.9 1.3e-20 72.9 0.6 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RPA_C PF08784.6 GAO88213.1 - 1.5e-23 83.1 0.4 9e-23 80.6 0.0 2.3 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 GAO88213.1 - 5.4e-05 22.9 1.2 0.00011 21.9 0.8 1.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MatE PF01554.13 GAO88214.1 - 7.1e-56 188.3 24.4 1.3e-30 106.1 5.9 2.4 2 0 0 2 2 2 2 MatE DUF202 PF02656.10 GAO88215.1 - 5.5e-21 74.5 4.7 1.5e-20 73.1 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1109 PF06532.6 GAO88215.1 - 0.0013 18.1 1.4 0.0015 17.9 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1109) COX4_pro_2 PF07835.7 GAO88215.1 - 0.047 13.6 2.2 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2499 PF10693.4 GAO88215.1 - 0.12 12.4 0.6 0.29 11.2 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) UPF0114 PF03350.11 GAO88215.1 - 3 7.7 5.5 0.29 11.0 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 zf-LITAF-like PF10601.4 GAO88215.1 - 3.3 7.6 5.1 2.6 7.9 1.8 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain NUDIX PF00293.23 GAO88216.1 - 2.9e-28 98.2 0.0 4.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain UFC1 PF08694.6 GAO88217.1 - 0.23 10.9 0.8 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.20 GAO88218.1 - 3.7e-24 85.2 0.0 6.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAO88218.1 - 6.6e-14 51.1 7.6 1.5e-08 34.1 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 GAO88218.1 - 4.4e-10 38.7 6.0 0.032 14.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 GAO88218.1 - 6.1e-06 26.4 1.5 1.1 9.5 0.0 4.2 1 1 3 4 4 4 4 HEAT repeats Pkinase_Tyr PF07714.12 GAO88218.1 - 2.5e-05 23.4 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2454 PF10521.4 GAO88218.1 - 0.0082 15.1 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 GAO88218.1 - 0.059 13.8 4.1 0.3 11.6 0.4 3.6 4 0 0 4 4 4 0 HEAT-like repeat IFRD PF05004.8 GAO88218.1 - 0.069 12.2 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DENN PF02141.16 GAO88219.1 - 2.3e-40 138.2 0.0 4.4e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAO88219.1 - 0.00063 19.6 0.0 0.002 18.0 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 GAO88219.1 - 0.013 15.8 5.7 0.013 15.8 3.9 2.9 2 1 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Microtub_assoc PF07989.6 GAO88219.1 - 1.1 9.0 11.9 0.09 12.6 1.7 2.8 2 1 0 2 2 2 0 Microtubule associated adh_short PF00106.20 GAO88220.1 - 4.4e-29 101.5 2.5 6.9e-29 100.8 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88220.1 - 7.3e-25 88.1 0.5 8.8e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88220.1 - 1.5e-13 50.7 2.8 4.9e-13 49.1 2.0 1.7 1 1 0 1 1 1 1 KR domain Spheroidin PF05541.7 GAO88220.1 - 0.15 9.6 0.0 0.17 9.4 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein RabGAP-TBC PF00566.13 GAO88221.1 - 5.4e-43 146.9 0.0 2.3e-41 141.6 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fungal_trans PF04082.13 GAO88222.1 - 2.8e-14 52.6 0.0 4.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88222.1 - 1.9e-10 40.4 2.8 3.3e-10 39.6 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ost4 PF10215.4 GAO88223.1 - 5.5e-19 67.3 1.4 6.8e-19 67.0 1.0 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase KOW PF00467.24 GAO88225.1 - 3.1e-06 26.6 1.0 8.4e-06 25.2 0.7 1.8 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.16 GAO88226.1 - 3.4e-32 109.8 0.0 4.8e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAO88226.1 - 8.6e-25 86.1 0.0 1.3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 GAO88226.1 - 0.045 12.1 0.0 0.06 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 GAO88226.1 - 0.31 10.8 2.0 0.57 9.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Ifi-6-16 PF06140.8 GAO88228.1 - 0.097 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Interferon-induced 6-16 family CPSase_L_D2 PF02786.12 GAO88230.1 - 2e-113 376.8 0.1 1.9e-83 278.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 GAO88230.1 - 1.2e-46 157.4 0.0 2.9e-46 156.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 GAO88230.1 - 4.1e-45 153.5 0.0 1.3e-44 151.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 GAO88230.1 - 1.2e-42 144.9 0.0 2.4e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 GAO88230.1 - 5.2e-41 139.2 0.0 1.4e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 GAO88230.1 - 2.4e-40 137.0 0.0 3.8e-19 68.8 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 GAO88230.1 - 1.2e-35 122.7 0.1 4.1e-35 120.9 0.0 2.1 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 GAO88230.1 - 4.2e-35 121.1 0.1 1.8e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 GAO88230.1 - 3.8e-22 78.0 0.0 2.8e-21 75.2 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 GAO88230.1 - 1.7e-21 76.3 0.0 1.7e-09 36.8 0.0 4.3 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAO88230.1 - 9e-16 57.8 0.4 2.8e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAO88230.1 - 1.1e-14 54.1 0.1 7.4e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 GAO88230.1 - 9.1e-06 25.2 0.0 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAO88230.1 - 1e-05 25.4 0.3 0.15 11.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.8 GAO88230.1 - 1.1e-05 24.9 0.2 0.00017 21.0 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 GAO88230.1 - 0.01 15.3 0.2 4.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 GAO88230.1 - 0.034 14.1 0.1 0.61 10.0 0.0 2.9 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.11 GAO88231.1 - 9e-35 120.0 31.1 1.4e-34 119.3 21.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 GAO88231.1 - 0.62 10.1 0.1 0.62 10.1 0.0 4.6 2 2 4 6 6 6 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 GAO88231.1 - 3.1 7.1 16.4 0.061 12.7 1.2 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4131) His_Phos_2 PF00328.17 GAO88232.1 - 8e-33 114.1 0.0 9.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.23 GAO88233.1 - 4.8e-82 275.5 0.0 6.1e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO88233.1 - 3e-11 44.0 0.2 6.8e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 GAO88234.1 - 1.2e-24 87.2 0.5 4.3e-12 46.4 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAO88234.1 - 1.2e-13 51.7 6.0 6.7e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAO88234.1 - 5.7e-07 29.3 0.0 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 GAO88234.1 - 0.00017 20.8 0.0 0.61 9.0 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.1 GAO88234.1 - 0.012 15.5 1.1 0.12 12.3 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAO88234.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 GAO88234.1 - 0.075 12.6 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 GAO88234.1 - 0.079 13.2 0.2 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO88234.1 - 0.092 12.8 0.3 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 GAO88234.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAO88234.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Vps51 PF08700.6 GAO88235.1 - 4.3e-18 64.9 1.6 1.1e-17 63.6 1.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 GAO88235.1 - 0.026 14.3 0.3 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.13 GAO88235.1 - 0.35 10.3 6.0 0.34 10.4 0.5 2.6 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain MAS20 PF02064.10 GAO88236.1 - 4.5e-17 62.0 1.3 3.6e-12 46.2 0.8 2.6 1 1 1 2 2 2 2 MAS20 protein import receptor Glyco_hydro_72 PF03198.9 GAO88237.1 - 3.9e-127 423.5 2.5 4.8e-127 423.2 1.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 GAO88237.1 - 2.8e-05 23.1 0.1 0.00019 20.4 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 GAO88237.1 - 0.0027 16.9 0.0 0.028 13.6 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 GAO88238.1 - 1.1e-11 44.3 0.2 2.2e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO88238.1 - 3.2e-10 39.3 0.5 1e-09 37.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 GAO88238.1 - 0.041 13.7 0.1 10 6.1 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2014 PF09427.5 GAO88238.1 - 0.23 10.5 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Mre11_DNA_bind PF04152.9 GAO88239.1 - 1.4e-61 207.4 2.9 1.4e-61 207.4 2.0 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 GAO88239.1 - 2.4e-27 95.6 2.7 3.5e-27 95.1 1.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 GAO88239.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF1446 PF07287.6 GAO88240.1 - 1.2e-128 428.6 0.0 1.4e-128 428.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Aldedh PF00171.17 GAO88241.1 - 8.8e-190 630.9 1.1 9.9e-190 630.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyridox_oxidase PF01243.15 GAO88242.1 - 0.00072 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.13 GAO88243.1 - 1.5e-07 30.5 0.5 1.9e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Smg4_UPF3 PF03467.10 GAO88244.1 - 1.8e-26 93.1 0.0 5.1e-26 91.7 0.0 1.8 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 GAO88244.1 - 2e-08 33.7 0.1 6.4e-07 28.9 0.0 3.1 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO88244.1 - 2.2e-05 24.3 0.0 0.00026 20.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88244.1 - 9.1e-05 22.2 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 GAO88245.1 - 3.1e-37 127.9 0.1 2.6e-32 111.8 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FAD_binding_3 PF01494.14 GAO88246.1 - 3.3e-83 279.6 0.0 4.1e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO88246.1 - 1.5e-49 167.8 0.0 2.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 GAO88246.1 - 1.2e-05 24.3 0.2 0.00028 19.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO88246.1 - 0.00015 20.7 0.1 0.00068 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAO88246.1 - 0.00022 20.4 0.1 0.00033 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO88246.1 - 0.00036 20.4 0.1 0.00094 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO88246.1 - 0.00044 20.1 0.1 0.0034 17.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO88246.1 - 0.00044 19.4 0.0 0.00078 18.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 GAO88246.1 - 0.0025 16.7 0.0 0.0079 15.0 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 GAO88246.1 - 0.0084 15.2 0.0 0.35 9.8 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAO88246.1 - 0.0086 16.4 0.0 0.13 12.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C33 PF05412.7 GAO88246.1 - 0.085 12.6 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase NUDIX PF00293.23 GAO88247.1 - 1e-11 44.5 0.2 1.7e-11 43.9 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain LRRC37AB_C PF14914.1 GAO88247.1 - 0.11 11.9 0.4 0.16 11.4 0.3 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Peptidase_M19 PF01244.16 GAO88248.1 - 6.4e-101 337.4 0.0 8.2e-101 337.1 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Radical_SAM PF04055.16 GAO88249.1 - 2.3e-24 86.4 0.1 5.4e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 GAO88249.1 - 9.2e-24 83.3 0.0 2.3e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 GAO88249.1 - 3.6e-11 43.2 0.0 6.6e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 Flavodoxin Flavodoxin_5 PF12724.2 GAO88249.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Fungal_trans PF04082.13 GAO88250.1 - 2e-08 33.4 0.7 4.3e-08 32.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2421 PF10334.4 GAO88250.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Consortin_C PF15281.1 GAO88250.1 - 0.093 12.2 1.4 0.2 11.1 0.9 1.5 1 0 0 1 1 1 0 Consortin C-terminus FANCI_S1-cap PF14674.1 GAO88250.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap Coatomer_E PF04733.9 GAO88251.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Amidohydro_2 PF04909.9 GAO88252.1 - 2.5e-41 142.0 0.0 3.2e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase GST_N PF02798.15 GAO88253.1 - 3.8e-09 36.5 0.0 6.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO88253.1 - 2.8e-06 27.7 0.0 5.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO88253.1 - 9.7e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO88253.1 - 5.2e-05 23.1 0.0 0.00021 21.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO88253.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO88253.1 - 0.00023 20.9 0.2 0.00055 19.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 GAO88254.1 - 9e-11 41.5 4.9 1.8e-10 40.5 3.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO88254.1 - 4.9e-08 32.1 0.0 6.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO88255.1 - 4e-36 124.4 39.8 4e-36 124.4 27.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO88255.1 - 1.6e-11 43.4 12.9 1.6e-11 43.4 9.0 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter Dynamin_N PF00350.18 GAO88256.1 - 3.3e-09 36.7 0.0 8.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family DUF258 PF03193.11 GAO88256.1 - 3.8e-05 22.9 0.0 0.00055 19.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAO88256.1 - 0.00029 20.7 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAO88256.1 - 0.0016 18.4 0.1 0.0016 18.4 0.0 4.7 3 2 1 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 GAO88256.1 - 0.002 18.4 0.4 0.012 15.8 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_33 PF13671.1 GAO88256.1 - 0.014 15.2 0.2 0.08 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Gly-rich_Ago1 PF12764.2 GAO88256.1 - 0.021 15.4 3.7 0.071 13.7 2.6 1.9 1 0 0 1 1 1 0 Glycine-rich region of argonaut Miro PF08477.8 GAO88256.1 - 0.068 13.6 0.0 0.29 11.6 0.0 2.2 3 0 0 3 3 1 0 Miro-like protein AIG1 PF04548.11 GAO88256.1 - 0.091 11.8 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family HJURP_C PF12347.3 GAO88256.1 - 0.14 11.7 0.3 4.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat AAA_10 PF12846.2 GAO88256.1 - 1.4 8.3 6.1 0.56 9.5 0.1 3.0 3 1 0 4 4 4 0 AAA-like domain Seryl_tRNA_N PF02403.17 GAO88256.1 - 7.7 6.5 8.1 0.7 9.9 0.7 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain AMP-binding PF00501.23 GAO88257.1 - 1.9e-244 810.5 0.0 4.7e-84 282.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAO88257.1 - 4.8e-145 482.0 0.0 1e-38 132.9 0.0 4.6 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAO88257.1 - 1.6e-39 133.9 1.3 3.2e-12 46.5 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO88257.1 - 9.1e-23 81.0 1.6 7.4e-10 39.6 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAO88257.1 - 2.4 6.5 0.6 27 3.0 0.0 2.5 3 0 0 3 3 3 0 Transferase family p450 PF00067.17 GAO88258.1 - 1.9e-59 201.4 0.0 2.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 GAO88259.1 - 2e-41 142.1 0.0 2.4e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAO88259.1 - 2.1e-10 39.8 0.0 3.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAO88259.1 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAO88259.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 GAO88259.1 - 0.0027 16.3 0.0 0.004 15.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.16 GAO88260.1 - 8.1e-101 337.2 0.0 9.8e-101 336.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III AMP-binding PF00501.23 GAO88261.1 - 2.4e-57 194.2 0.0 3e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO88261.1 - 0.0029 18.5 0.0 0.0077 17.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 GAO88262.1 - 3.7e-06 27.1 0.1 4.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAO88262.1 - 0.00074 19.4 0.4 0.00093 19.1 0.3 1.2 1 1 0 1 1 1 1 Acyl-carrier HpcH_HpaI PF03328.9 GAO88263.1 - 2.2e-26 92.1 0.0 3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2OG-FeII_Oxy PF03171.15 GAO88264.1 - 2.4e-13 50.1 0.0 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAO88264.1 - 9.9e-12 45.4 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Aminotran_5 PF00266.14 GAO88266.1 - 5e-45 153.8 0.0 1.2e-44 152.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAO88266.1 - 0.00039 18.8 0.0 0.00072 17.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAO88266.1 - 0.00089 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TauD PF02668.11 GAO88267.1 - 6.8e-39 134.0 0.1 8.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAO88269.1 - 1.3e-09 37.2 0.2 1.4e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 GAO88269.1 - 0.011 13.8 0.1 0.014 13.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.19 GAO88269.1 - 0.069 11.7 0.1 0.11 11.0 0.0 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter Rieske PF00355.21 GAO88270.1 - 0.058 12.9 1.0 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain ASCH PF04266.9 GAO88271.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 ASCH domain APH PF01636.18 GAO88273.1 - 4.2e-09 36.4 0.9 1.7e-08 34.4 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO88273.1 - 0.0073 15.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase DUF3816 PF12822.2 GAO88274.1 - 3.8 7.3 21.4 3.6 7.4 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Abhydrolase_6 PF12697.2 GAO88275.1 - 9.6e-30 104.1 0.2 2.3e-29 102.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO88275.1 - 5.4e-16 58.8 0.0 3.2e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO88275.1 - 5.8e-10 39.0 0.0 2e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAO88275.1 - 7.7e-07 27.8 0.0 1.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 GAO88275.1 - 0.028 13.8 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_4 PF08386.5 GAO88275.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein EthD PF07110.6 GAO88275.1 - 0.092 13.6 0.2 7.9 7.4 0.0 3.2 3 0 0 3 3 3 0 EthD domain Lactonase PF10282.4 GAO88276.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LmjF365940-deam PF14421.1 GAO88276.1 - 0.041 13.2 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases CMD PF02627.15 GAO88277.1 - 4.6e-15 55.2 0.3 7.1e-12 45.0 0.1 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Cellulase PF00150.13 GAO88278.1 - 1.7e-53 181.6 7.6 2e-52 178.1 5.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAO88278.1 - 3e-15 55.5 9.1 3e-15 55.5 6.3 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_7 PF00840.15 GAO88279.1 - 1.6e-223 741.8 26.2 2e-223 741.4 18.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAO88279.1 - 4.1e-15 55.1 9.1 4.1e-15 55.1 6.3 4.1 5 0 0 5 5 5 1 Fungal cellulose binding domain DUF3439 PF11921.3 GAO88279.1 - 0.79 9.4 8.2 2.1 8.1 5.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Formyl_trans_N PF00551.14 GAO88280.1 - 1.8e-37 128.6 0.1 2.5e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 GAO88280.1 - 5.9e-09 35.2 0.0 1.7e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 GAO88280.1 - 0.00029 20.4 0.4 0.00096 18.8 0.0 2.2 2 2 1 3 3 3 1 ACT domain Peptidase_M20 PF01546.23 GAO88281.1 - 2.1e-09 37.1 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 VIGSSK PF14773.1 GAO88281.1 - 0.068 13.0 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal NAD_binding_8 PF13450.1 GAO88282.1 - 4.4e-14 52.2 0.9 1.6e-12 47.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO88282.1 - 6.8e-05 22.6 0.0 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO88282.1 - 0.00027 20.8 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO88282.1 - 0.00041 19.3 0.0 0.0092 14.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO88282.1 - 0.0017 18.7 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO88282.1 - 0.0021 16.5 0.0 0.0068 14.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO88282.1 - 0.0037 16.1 0.1 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAO88282.1 - 0.0057 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAO88282.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 GAO88282.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAO88282.1 - 0.021 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAO88282.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 GAO88282.1 - 0.24 11.0 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.13 GAO88283.1 - 1.9e-42 144.6 0.2 3.8e-40 137.1 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAO88283.1 - 1.5e-23 83.0 0.9 3.2e-22 78.7 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO88283.1 - 7.5e-21 74.3 0.0 1.9e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain p450 PF00067.17 GAO88284.1 - 3.1e-53 180.9 0.0 5e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO88285.1 - 1.6e-30 106.0 0.0 2.1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 GAO88286.1 - 1.2e-70 238.3 0.0 2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 GAO88286.1 - 8.3e-66 222.0 0.0 1.9e-65 220.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAO88286.1 - 4.3e-61 205.7 1.2 3.1e-60 202.9 0.1 3.2 5 0 0 5 5 5 1 KR domain PS-DH PF14765.1 GAO88286.1 - 1.4e-57 195.1 0.1 2.3e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 GAO88286.1 - 7.5e-52 175.7 0.0 1.9e-51 174.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAO88286.1 - 2.2e-49 167.5 1.9 4.4e-49 166.6 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO88286.1 - 5.2e-30 103.7 0.1 1.3e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO88286.1 - 8.1e-19 67.9 0.0 2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO88286.1 - 4.4e-18 65.0 0.0 1.1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO88286.1 - 8.2e-14 52.5 0.0 3.9e-13 50.4 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAO88286.1 - 6.6e-13 48.6 0.0 2.5e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 GAO88286.1 - 1.2e-11 44.5 0.0 1e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 GAO88286.1 - 5.1e-10 39.1 0.0 2e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO88286.1 - 2.4e-08 34.3 0.0 8.4e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88286.1 - 2.8e-07 31.1 0.0 2.1e-06 28.3 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 GAO88286.1 - 0.0002 21.0 0.6 0.00068 19.3 0.2 2.1 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 GAO88286.1 - 0.0044 16.1 0.0 0.0098 15.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 GAO88286.1 - 0.012 15.8 0.0 0.039 14.2 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Shikimate_DH PF01488.15 GAO88286.1 - 0.027 14.5 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thiolase_N PF00108.18 GAO88286.1 - 0.044 12.7 0.3 0.099 11.6 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain HsbA PF12296.3 GAO88288.1 - 2e-29 101.9 0.9 2.5e-29 101.6 0.6 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF566 PF04484.7 GAO88289.1 - 1.6 8.1 9.8 2.4 7.6 6.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dynamin_N PF00350.18 GAO88290.1 - 7.5e-30 103.9 0.0 1.6e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAO88290.1 - 1.5e-17 63.3 0.1 5.4e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAO88290.1 - 4.7e-05 23.3 0.0 0.00022 21.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 GAO88290.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAO88290.1 - 0.018 15.5 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 GAO88290.1 - 0.023 14.2 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 GAO88290.1 - 0.12 11.6 0.0 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B GMC_oxred_N PF00732.14 GAO88291.1 - 9.7e-52 175.9 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO88291.1 - 1.5e-43 148.5 0.2 3.4e-43 147.3 0.1 1.6 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO88291.1 - 8.6e-09 34.7 0.4 3e-05 23.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAO88291.1 - 5.3e-06 26.4 0.4 2.1e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO88291.1 - 2.2e-05 23.5 4.3 8.2e-05 21.6 2.0 2.4 2 2 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO88291.1 - 0.00034 19.7 0.2 0.00064 18.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAO88291.1 - 0.00064 18.7 0.2 0.0011 17.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAO88291.1 - 0.0037 15.8 0.3 0.0059 15.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAO88291.1 - 0.0039 17.1 1.4 0.011 15.7 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAO88291.1 - 0.013 14.3 0.9 0.022 13.6 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO88291.1 - 0.016 13.8 0.5 0.15 10.6 0.7 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ELFV_dehydrog_N PF02812.13 GAO88291.1 - 0.042 13.4 0.1 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FAD_oxidored PF12831.2 GAO88291.1 - 0.048 12.7 2.8 0.097 11.7 1.5 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO88291.1 - 0.05 13.6 0.6 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO88291.1 - 0.22 11.9 1.3 1.2 9.6 0.8 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase PNP_UDP_1 PF01048.15 GAO88292.1 - 1.4e-08 33.9 0.5 9.4e-08 31.3 0.4 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily adh_short PF00106.20 GAO88294.1 - 9.1e-17 61.4 0.1 1.5e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88294.1 - 1.2e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88294.1 - 0.00033 20.3 0.1 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO88294.1 - 0.0022 17.4 0.2 0.0051 16.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3425 PF11905.3 GAO88295.1 - 3.6e-23 81.9 0.5 6.3e-23 81.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NmrA PF05368.8 GAO88295.1 - 1e-16 60.9 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family HTH_24 PF13412.1 GAO88296.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EthD PF07110.6 GAO88297.1 - 1.5e-17 64.2 0.3 1.9e-17 63.9 0.2 1.1 1 0 0 1 1 1 1 EthD domain DUF1772 PF08592.6 GAO88298.1 - 2e-25 89.1 3.4 2.2e-25 89.0 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4234 PF14018.1 GAO88298.1 - 0.05 13.3 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Lactamase_B PF00753.22 GAO88299.1 - 1.5e-22 80.2 5.4 2e-22 79.7 3.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO88299.1 - 2.1e-05 24.1 2.8 3.4e-05 23.4 1.9 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO88299.1 - 0.028 14.1 0.2 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Antimicrobial14 PF08109.6 GAO88299.1 - 0.22 11.3 2.9 7 6.5 0.0 3.6 3 1 0 3 3 3 0 Lactocin 705 family adh_short_C2 PF13561.1 GAO88300.1 - 4e-06 26.7 0.0 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO88300.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88300.1 - 0.00011 21.8 0.0 0.00081 19.0 0.0 2.0 2 0 0 2 2 2 1 KR domain ADH_N PF08240.7 GAO88301.1 - 2.6e-25 88.2 4.6 4.5e-25 87.5 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO88301.1 - 4.4e-19 68.3 0.0 6.3e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO88301.1 - 2.7e-05 25.0 0.0 4.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 GAO88301.1 - 0.0012 18.4 0.2 0.0018 17.8 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 GAO88301.1 - 0.0015 17.6 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4243 PF14027.1 GAO88302.1 - 5.8e-92 308.6 0.0 7e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AflR PF08493.5 GAO88303.1 - 2.1e-11 43.3 7.6 2.1e-11 43.3 5.3 3.5 2 1 0 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 GAO88303.1 - 8.2e-08 32.0 10.3 8.2e-08 32.0 7.1 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSFA2_C PF14723.1 GAO88303.1 - 3.3 7.3 5.7 4.4 7.0 0.4 2.6 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus MFS_1 PF07690.11 GAO88304.1 - 2e-44 151.7 44.9 2e-44 151.7 31.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO88304.1 - 4.5e-10 38.3 21.6 6.7e-10 37.7 14.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO88304.1 - 1.3e-08 33.9 13.9 1.3e-08 33.9 9.6 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter adh_short_C2 PF13561.1 GAO88305.1 - 8.9e-22 78.0 0.0 1e-21 77.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO88305.1 - 7e-13 48.8 0.8 8.7e-13 48.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88305.1 - 7.2e-05 22.5 0.5 0.00014 21.6 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO88305.1 - 0.0008 19.4 1.6 0.0016 18.4 1.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAO88305.1 - 0.0026 17.4 0.5 0.0067 16.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO88305.1 - 0.0037 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAO88305.1 - 0.036 13.1 0.1 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain XdhC_C PF13478.1 GAO88305.1 - 0.042 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 GAO88305.1 - 0.05 13.2 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO88305.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1993 PF09351.5 GAO88306.1 - 8.2e-32 110.3 0.0 9.9e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) p450 PF00067.17 GAO88307.1 - 1.2e-66 225.1 0.0 1.9e-66 224.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Scytalone_dh PF02982.9 GAO88308.1 - 5.3e-63 211.3 0.8 6e-63 211.1 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAO88308.1 - 2.6e-09 37.0 1.0 3e-09 36.8 0.7 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAO88308.1 - 0.41 10.8 2.9 4.5 7.5 2.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) adh_short PF00106.20 GAO88309.1 - 1.9e-30 105.9 0.5 2.6e-30 105.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88309.1 - 2.3e-26 93.0 0.0 2.8e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88309.1 - 4e-12 46.1 0.2 5.8e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAO88309.1 - 0.055 12.5 0.0 0.078 12.0 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAO88309.1 - 0.094 12.1 0.2 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ORC2 PF04084.9 GAO88309.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 2 NAD_binding_10 PF13460.1 GAO88310.1 - 2.2e-07 31.0 0.0 6.2e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding SnoaL_2 PF12680.2 GAO88310.1 - 1.4e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_11 PF08241.7 GAO88311.1 - 4.3e-14 52.7 0.0 9.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88311.1 - 6.9e-11 42.7 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO88311.1 - 7.1e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO88311.1 - 3.9e-09 36.4 0.0 6.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88311.1 - 3.3e-08 33.2 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO88311.1 - 4.9e-07 30.0 0.0 8.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO88311.1 - 3.3e-05 23.9 0.1 8.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAO88311.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 GAO88311.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF4081 PF13312.1 GAO88311.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) CheR PF01739.13 GAO88311.1 - 0.063 12.5 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 GAO88311.1 - 0.086 11.7 0.0 0.78 8.6 0.0 2.0 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_29 PF03141.11 GAO88311.1 - 0.092 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 GAO88311.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ketoacyl-synt PF00109.21 GAO88312.1 - 2.7e-72 243.2 0.1 3.5e-71 239.6 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO88312.1 - 4.5e-52 177.3 0.1 1.1e-51 176.1 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAO88312.1 - 1.9e-32 111.5 1.2 1.9e-32 111.5 0.8 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO88312.1 - 2.4e-07 30.9 0.5 6.7e-07 29.4 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO88312.1 - 4.1e-05 22.7 0.2 0.00015 20.8 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF4267 PF14087.1 GAO88313.1 - 9.8e-15 54.1 1.1 1.2e-14 53.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) LIP PF03583.9 GAO88314.1 - 3.7e-80 269.2 0.0 4.8e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 GAO88314.1 - 0.00071 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Terpene_synth_C PF03936.11 GAO88315.1 - 8.9e-11 41.5 0.5 1.3e-10 40.9 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 GAO88316.1 - 1.6e-27 96.1 24.6 1.6e-27 96.1 17.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAA_hydrolase PF01557.13 GAO88317.1 - 1.1e-59 201.5 0.0 1.4e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RPE65 PF03055.10 GAO88318.1 - 9.9e-141 469.6 0.0 1.1e-140 469.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.13 GAO88319.1 - 8e-33 113.4 0.0 1.3e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88319.1 - 2.4e-11 43.3 4.0 4.6e-11 42.4 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 GAO88319.1 - 0.046 13.6 0.5 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor TPR_12 PF13424.1 GAO88319.1 - 0.12 12.2 0.1 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupin_2 PF07883.6 GAO88320.1 - 3.7e-24 84.0 1.9 9.3e-16 57.1 0.5 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 GAO88320.1 - 2.3e-07 30.5 1.3 0.0004 20.0 0.3 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 GAO88320.1 - 4.8e-07 29.0 0.1 0.038 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAO88320.1 - 0.00055 19.3 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Cupin ARD PF03079.9 GAO88320.1 - 0.012 15.6 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 ARD/ARD' family CENP-C_C PF11699.3 GAO88320.1 - 0.075 13.0 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Mif2/CENP-C like FAD_binding_3 PF01494.14 GAO88321.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO88321.1 - 4.8e-10 38.8 5.4 8.9e-05 21.5 1.8 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO88321.1 - 1.3e-07 31.4 0.1 3.8e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO88321.1 - 3e-05 24.3 0.0 0.0029 17.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO88321.1 - 4e-05 22.4 1.5 0.13 10.8 0.1 2.9 2 1 1 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 GAO88321.1 - 9.7e-05 21.6 0.6 0.0049 15.9 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 GAO88321.1 - 0.00015 20.7 2.1 0.00027 19.9 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO88321.1 - 0.00031 20.6 1.2 0.00093 19.1 0.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO88321.1 - 0.0035 16.3 0.0 0.0072 15.2 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAO88321.1 - 0.0039 17.2 0.0 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO88321.1 - 0.0044 16.1 0.5 0.027 13.5 0.4 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAO88321.1 - 0.0066 14.9 1.1 0.039 12.4 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAO88321.1 - 0.069 11.9 2.0 0.15 10.8 1.4 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAO88321.1 - 0.11 11.5 4.6 0.19 10.7 3.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aldedh PF00171.17 GAO88322.1 - 1.4e-105 353.2 0.0 1.7e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lipase3_N PF03893.11 GAO88322.1 - 0.015 15.1 0.3 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 Lipase 3 N-terminal region ABC2_membrane PF01061.19 GAO88324.1 - 1.8e-89 298.4 49.8 1.9e-48 164.4 12.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAO88324.1 - 1.5e-40 138.7 0.0 1.9e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO88324.1 - 8.8e-29 99.2 0.0 1.6e-22 79.0 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAO88324.1 - 1.2e-12 47.5 32.4 7.2e-07 28.5 3.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAO88324.1 - 9e-10 38.5 0.1 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 GAO88324.1 - 9.1e-06 24.9 0.0 0.0037 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO88324.1 - 4.8e-05 22.8 0.0 0.013 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO88324.1 - 0.00014 21.9 0.1 0.081 13.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO88324.1 - 0.00041 20.3 0.3 0.028 14.3 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 GAO88324.1 - 0.00081 19.3 0.5 0.3 11.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAO88324.1 - 0.00082 20.1 0.0 1.3 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAO88324.1 - 0.0014 18.0 1.6 0.54 9.6 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO88324.1 - 0.002 18.0 0.0 0.97 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 GAO88324.1 - 0.0023 17.4 0.4 1.4 8.3 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 GAO88324.1 - 0.0027 17.2 0.7 0.077 12.5 0.1 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAO88324.1 - 0.004 17.4 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAO88324.1 - 0.014 15.0 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 GAO88324.1 - 0.021 14.5 1.4 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 GAO88324.1 - 0.035 14.0 0.2 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 GAO88324.1 - 0.045 13.7 0.0 7.7 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO88324.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 1 0 Dynamin family UPF0079 PF02367.12 GAO88324.1 - 0.083 12.5 0.8 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAO88324.1 - 0.12 11.9 0.5 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 GAO88324.1 - 0.13 12.4 0.2 31 4.7 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 GAO88324.1 - 0.16 11.1 0.1 1 8.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAO88324.1 - 0.19 12.2 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 GAO88324.1 - 0.26 10.8 0.5 12 5.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAO88324.1 - 0.36 9.7 0.1 18 4.2 0.0 2.2 2 0 0 2 2 2 0 Septin NmrA PF05368.8 GAO88325.1 - 6.6e-14 51.7 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO88325.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO88325.1 - 0.12 12.0 1.9 2.5 7.7 0.2 2.9 2 1 1 3 3 3 0 KR domain TauD PF02668.11 GAO88326.1 - 2.3e-34 119.2 0.0 2.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PhyH PF05721.8 GAO88327.1 - 8e-20 71.7 0.0 1.1e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Transferase PF02458.10 GAO88328.1 - 2.2e-21 75.7 0.0 1.9e-20 72.7 0.0 1.9 2 0 0 2 2 2 2 Transferase family Tyrosinase PF00264.15 GAO88329.1 - 5.6e-42 144.3 0.4 7.6e-42 143.9 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Methyltransf_3 PF01596.12 GAO88329.1 - 3.6e-29 101.2 0.0 4.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAO88329.1 - 5.6e-16 59.2 0.1 1.4e-15 57.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88329.1 - 3.2e-12 47.0 0.0 7.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88329.1 - 1.1e-09 38.0 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO88329.1 - 1.1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO88329.1 - 8.7e-07 29.2 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAO88329.1 - 3.1e-05 23.4 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 GAO88329.1 - 3.6e-05 22.9 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 GAO88329.1 - 8.2e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAO88329.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 GAO88329.1 - 0.00043 20.7 0.0 0.00088 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 GAO88329.1 - 0.0005 19.4 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_23 PF13489.1 GAO88329.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAO88329.1 - 0.023 15.1 0.0 0.066 13.6 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain DUF633 PF04816.7 GAO88329.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF633) Met_10 PF02475.11 GAO88329.1 - 0.052 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.4 GAO88329.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 1 0 Putative methyltransferase Methyltransf_15 PF09445.5 GAO88329.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.5 GAO88329.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 GAO88329.1 - 0.17 10.9 0.1 0.31 10.0 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase p450 PF00067.17 GAO88330.1 - 8.3e-65 219.0 0.0 1.1e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAO88331.1 - 4e-37 127.7 49.9 4e-37 127.7 34.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO88331.1 - 2.9e-13 48.8 21.8 9.8e-13 47.1 15.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO88331.1 - 8.4e-10 37.8 43.1 3.8e-07 29.0 10.6 3.7 3 1 1 4 4 4 2 Sugar (and other) transporter AMP-binding PF00501.23 GAO88332.1 - 2.3e-79 266.7 0.1 3.4e-79 266.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAO88332.1 - 4e-54 183.1 0.0 6.4e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAO88332.1 - 3.9e-14 52.6 0.1 8.5e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAO88332.1 - 6.2e-06 25.8 0.0 4.3e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 GAO88332.1 - 0.001 19.9 0.7 0.029 15.3 0.3 3.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAO88332.1 - 0.1 11.2 0.0 0.42 9.2 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Baculo_11_kDa PF06143.6 GAO88333.1 - 0.37 10.1 1.1 0.57 9.5 0.0 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ferric_reduct PF01794.14 GAO88333.1 - 1.3 9.1 12.0 4.6 7.3 6.1 2.9 2 1 0 2 2 2 0 Ferric reductase like transmembrane component NmrA PF05368.8 GAO88334.1 - 5.7e-38 130.4 0.0 8.3e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO88334.1 - 1.3e-12 48.1 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO88334.1 - 0.0079 15.6 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAO88334.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAO88334.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 GAO88335.1 - 2.2e-56 191.3 0.0 3e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAO88336.1 - 5.5e-36 123.9 45.4 5.5e-36 123.9 31.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO88336.1 - 6.4e-14 51.3 8.1 6.4e-14 51.3 5.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO88336.1 - 5.7e-13 47.9 19.1 7.7e-13 47.4 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.19 GAO88337.1 - 1.4e-15 57.4 13.2 1.4e-15 57.4 9.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAO88337.1 - 1.9e-14 53.2 0.0 3.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acetyltransf_1 PF00583.19 GAO88338.1 - 1.2e-07 31.6 0.2 1.1e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO88338.1 - 0.00018 21.1 0.2 0.046 13.4 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 GAO88338.1 - 0.00066 19.7 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 GAO88338.1 - 0.0062 16.8 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.20 GAO88339.1 - 2.3e-25 89.2 0.0 4.6e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAO88339.1 - 2.8e-22 78.8 2.5 3.6e-07 30.4 0.0 6.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88339.1 - 5.4e-18 63.8 12.1 3e-07 29.9 0.1 8.1 8 0 0 8 8 8 3 Ankyrin repeat Pkinase_Tyr PF07714.12 GAO88339.1 - 7.5e-17 61.2 0.0 1.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.1 GAO88339.1 - 8.8e-13 48.0 6.0 2.3e-05 24.4 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88339.1 - 1.4e-12 46.5 5.9 0.0022 18.0 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 GAO88339.1 - 6e-09 36.1 6.0 9.2e-05 22.8 0.1 6.0 7 0 0 7 7 7 2 Ankyrin repeats (many copies) Kdo PF06293.9 GAO88339.1 - 0.00095 18.2 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAO88339.1 - 0.38 9.4 0.0 0.62 8.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HeLo PF14479.1 GAO88340.1 - 6e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 GAO88340.1 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88340.1 - 0.0088 15.1 0.0 3.1 6.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Metallophos PF00149.23 GAO88341.1 - 3.8e-09 36.2 8.2 9.2e-09 34.9 5.7 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO88341.1 - 6.7e-06 26.0 0.6 1.2e-05 25.1 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-PARP PF00645.13 GAO88341.1 - 0.0012 19.0 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF4661 PF15576.1 GAO88341.1 - 0.16 11.6 3.4 0.27 10.8 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TPR_12 PF13424.1 GAO88342.1 - 1e-90 297.7 2.9 8.3e-18 64.1 0.0 5.5 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 GAO88342.1 - 1.7e-89 291.5 0.1 6.8e-12 44.9 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 GAO88342.1 - 2.1e-24 83.3 4.7 0.0027 17.4 0.1 9.2 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAO88342.1 - 1.6e-21 74.3 3.5 0.022 14.6 0.0 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO88342.1 - 2e-15 55.6 5.6 1.3 9.3 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAO88342.1 - 2.1e-15 55.5 11.8 0.038 13.6 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAO88342.1 - 4.7e-15 54.9 13.1 4.9e-05 22.8 0.0 6.3 3 1 5 9 9 7 5 TPR repeat TPR_19 PF14559.1 GAO88342.1 - 4.8e-15 55.6 1.8 0.021 15.1 0.2 7.7 6 1 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO88342.1 - 7.2e-14 52.0 0.5 0.039 14.6 0.1 5.6 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO88342.1 - 1.5e-11 43.8 2.5 1.2 9.9 0.0 8.3 7 2 2 9 9 7 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAO88342.1 - 4.1e-11 42.2 0.0 1e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Apc3 PF12895.2 GAO88342.1 - 7.8e-10 38.7 0.4 0.041 14.0 0.1 4.5 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.17 GAO88342.1 - 8.5e-09 34.6 0.0 1.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.15 GAO88342.1 - 2.5e-08 33.3 2.3 11 6.2 0.0 7.4 7 0 0 7 7 7 0 PPR repeat TPR_4 PF07721.9 GAO88342.1 - 7.8e-08 32.0 0.1 21 5.9 0.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat AAA_16 PF13191.1 GAO88342.1 - 6.8e-07 29.4 0.1 6.2e-06 26.3 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO88342.1 - 6.4e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF4074 PF13293.1 GAO88342.1 - 1.1e-05 25.6 0.1 55 4.0 0.0 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4074) NACHT PF05729.7 GAO88342.1 - 0.00013 21.6 0.0 0.00054 19.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TPR_8 PF13181.1 GAO88342.1 - 0.0033 17.0 13.0 11 6.1 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat AAA_14 PF13173.1 GAO88342.1 - 0.0036 17.1 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAO88342.1 - 0.0047 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase TPR_6 PF13174.1 GAO88342.1 - 0.039 14.4 11.8 25 5.6 0.1 7.9 9 0 0 9 9 7 0 Tetratricopeptide repeat AAA_17 PF13207.1 GAO88342.1 - 0.15 12.8 0.0 0.97 10.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain Fungal_trans PF04082.13 GAO88343.1 - 1.5e-23 83.0 0.6 2.7e-23 82.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88343.1 - 4.7e-05 23.2 10.3 8.4e-05 22.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid2 PF04478.7 GAO88344.1 - 0.0022 17.4 0.5 0.0037 16.6 0.3 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 GAO88344.1 - 0.02 14.2 0.1 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.13 GAO88345.1 - 6.5e-28 97.3 0.1 1.3e-27 96.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.16 GAO88345.1 - 1.3e-11 44.2 4.2 2.6e-11 43.3 2.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO88345.1 - 1.9e-07 30.7 4.6 1.9e-07 30.7 3.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAO88345.1 - 0.0006 20.0 5.8 0.0013 18.9 4.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor FKBP_C PF00254.23 GAO88346.1 - 3.6e-33 113.4 0.0 4.1e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Gly-zipper_OmpA PF13436.1 GAO88347.1 - 0.15 11.7 15.4 1.8 8.2 0.1 3.8 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain ABM PF03992.11 GAO88349.1 - 0.0041 17.1 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Glyco_hydro_11 PF00457.12 GAO88350.1 - 1.1e-78 262.8 22.2 1.6e-78 262.3 15.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sugar_tr PF00083.19 GAO88350.1 - 1.3e-23 83.3 9.4 2e-23 82.6 6.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Arylsulfotran_2 PF14269.1 GAO88351.1 - 6.2e-40 137.2 0.0 9.5e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO88351.1 - 3e-10 39.2 0.0 7.9e-09 34.5 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) GDPD PF03009.12 GAO88352.1 - 1.3e-13 51.0 0.0 5.4e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CoA_trans PF01144.18 GAO88353.1 - 9.2e-105 348.6 2.0 9e-63 211.3 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase UCH PF00443.24 GAO88354.1 - 8.8e-47 159.4 0.0 2e-46 158.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 GAO88354.1 - 8.8e-47 156.3 3.3 2.4e-22 78.0 0.1 4.9 5 0 0 5 5 5 3 A repeated domain in UCH-protein UCH_1 PF13423.1 GAO88354.1 - 8.8e-11 41.7 0.2 1.5e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.13 GAO88354.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 E7 protein, Early protein Tim17 PF02466.14 GAO88355.1 - 7e-15 55.1 7.4 1e-14 54.6 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1358 PF07096.6 GAO88355.1 - 0.13 11.9 2.0 0.18 11.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) PH PF00169.24 GAO88356.1 - 2.2e-11 43.8 0.1 9e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF269 PF03270.8 GAO88356.1 - 0.0079 16.1 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF269 RRM_1 PF00076.17 GAO88358.1 - 4.2e-51 170.4 0.0 9.7e-18 63.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO88358.1 - 2e-43 146.1 0.0 2.8e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88358.1 - 1.5e-25 88.7 0.0 1.5e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAO88358.1 - 3.6e-06 26.6 0.1 0.48 10.2 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 GAO88358.1 - 4.2e-05 23.3 0.0 2.5 8.0 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 GAO88358.1 - 0.014 14.7 0.0 0.085 12.2 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain THRAP3_BCLAF1 PF15440.1 GAO88358.1 - 4.1 5.9 30.4 7.2 5.1 21.1 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family GRP PF07172.6 GAO88358.1 - 6.6 7.2 48.3 0.2 12.1 2.9 3.5 3 0 0 3 3 3 0 Glycine rich protein family COQ9 PF08511.6 GAO88359.1 - 2.5e-23 81.3 0.1 4.2e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 COQ9 PPR_2 PF13041.1 GAO88360.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family WD40 PF00400.27 GAO88361.1 - 1.8e-16 59.3 5.7 2.5e-05 23.9 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat RasGAP PF00616.14 GAO88362.1 - 6.5e-45 153.2 0.0 1.2e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 GAO88362.1 - 3.1e-06 26.9 0.1 7.2e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain APG9 PF04109.11 GAO88363.1 - 1.6e-172 573.5 3.5 2.2e-172 573.1 2.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 GAO88364.1 - 7.4e-177 588.5 0.0 7.4e-177 588.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 GAO88364.1 - 2.8e-51 172.9 2.1 2.8e-51 172.9 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 GAO88365.1 - 0.0004 19.5 0.1 0.00098 18.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2188 PF09954.4 GAO88365.1 - 0.91 9.4 3.5 3.6 7.5 0.0 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Aminotran_1_2 PF00155.16 GAO88366.1 - 4.3e-38 131.1 0.0 5.2e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAO88366.1 - 0.0085 14.4 0.0 0.02 13.1 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.10 GAO88367.1 - 0 1505.0 0.0 0 1504.6 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 GAO88367.1 - 8.8e-40 135.2 0.7 2.2e-39 134.0 0.5 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 GAO88368.1 - 2.2e-134 447.3 7.9 2.9e-134 446.9 5.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAO88368.1 - 1.3e-24 86.5 5.8 4e-24 84.9 4.0 1.9 1 0 0 1 1 1 1 X8 domain DUF4189 PF13827.1 GAO88368.1 - 0.26 11.5 5.4 0.94 9.7 3.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) SprT-like PF10263.4 GAO88369.1 - 2.9e-52 176.5 0.4 4.5e-52 175.8 0.3 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 GAO88369.1 - 0.023 14.7 0.9 0.092 12.7 0.1 2.3 2 0 0 2 2 2 0 Peptidase MA superfamily DUF2161 PF09929.4 GAO88369.1 - 0.082 12.8 1.6 6.9 6.6 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) Mog1 PF04603.7 GAO88370.1 - 1.3e-13 51.0 0.2 6.1e-09 35.9 0.0 3.1 1 1 1 2 2 2 2 Ran-interacting Mog1 protein NYN PF01936.13 GAO88371.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.8 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 GAO88372.1 - 6.6e-28 96.5 7.6 1.4e-27 95.5 4.8 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 Reo_sigmaC PF04582.7 GAO88373.1 - 0.0062 15.7 0.5 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Jnk-SapK_ap_N PF09744.4 GAO88373.1 - 0.009 16.0 15.2 0.077 12.9 5.0 2.9 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 Laminin_II PF06009.7 GAO88373.1 - 0.015 15.0 4.7 0.27 10.9 0.1 2.8 1 1 1 3 3 3 0 Laminin Domain II Cob_adeno_trans PF01923.13 GAO88373.1 - 0.033 13.9 7.9 0.085 12.6 0.2 3.0 2 1 1 3 3 3 0 Cobalamin adenosyltransferase AAA_13 PF13166.1 GAO88373.1 - 0.041 12.3 4.1 0.046 12.1 2.1 1.6 1 1 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 GAO88373.1 - 0.073 13.3 2.1 11 6.3 0.1 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.1 GAO88373.1 - 0.081 12.9 6.0 1.3 9.1 0.2 2.7 2 1 0 3 3 2 0 Syntaxin-like protein DUF342 PF03961.8 GAO88373.1 - 0.13 10.6 5.8 0.11 10.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Bcr-Abl_Oligo PF09036.5 GAO88373.1 - 0.14 12.1 0.9 0.6 10.0 0.0 2.3 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Syntaxin PF00804.20 GAO88373.1 - 0.15 12.2 5.6 0.12 12.5 0.3 2.6 2 2 1 3 3 3 0 Syntaxin DUF1319 PF07028.6 GAO88373.1 - 0.62 10.2 7.1 7.6 6.7 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) IFT57 PF10498.4 GAO88373.1 - 0.63 8.7 8.4 1.4 7.6 1.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 GAO88373.1 - 1.5 8.5 20.1 5.3 6.8 1.9 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 GAO88373.1 - 1.7 8.8 6.2 14 5.8 0.1 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 GAO88373.1 - 1.7 8.4 3.9 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 GAO88373.1 - 5.7 7.4 9.2 39 4.7 0.2 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.1 GAO88373.1 - 6 7.2 8.1 1.3 9.4 0.8 2.9 2 2 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 GAO88373.1 - 7.6 4.2 6.6 8 4.1 2.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family COG6 PF06419.6 GAO88374.1 - 1e-250 833.1 0.1 1.2e-250 832.9 0.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 GAO88374.1 - 0.015 15.1 1.9 0.075 12.9 1.3 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.11 GAO88374.1 - 0.039 12.8 1.7 0.074 11.8 1.2 1.4 1 0 0 1 1 1 0 RmuC family Tnp_DNA_bind PF14706.1 GAO88374.1 - 0.13 11.9 0.2 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Transposase DNA-binding NIF3 PF01784.13 GAO88375.1 - 3.5e-56 190.5 0.0 4.3e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) AAA_30 PF13604.1 GAO88375.1 - 0.087 12.3 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain BolA PF01722.13 GAO88376.1 - 3.7e-21 74.8 0.0 5.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 GAO88377.1 - 1e-28 99.7 0.0 1.3e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAO88377.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 GAO88378.1 - 3.2e-24 85.0 2.8 6.9e-24 84.0 1.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 GAO88378.1 - 3.3e-17 62.4 0.0 6.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain IncA PF04156.9 GAO88378.1 - 0.067 12.7 3.8 0.11 12.1 2.6 1.3 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 GAO88378.1 - 0.098 13.0 7.0 0.18 12.1 3.9 2.3 2 0 0 2 2 2 0 SlyX W2 PF02020.13 GAO88379.1 - 2.2e-17 62.7 5.8 2.2e-17 62.7 4.1 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 GAO88379.1 - 1e-11 43.7 12.1 2.3e-05 23.6 0.4 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 GAO88379.1 - 2.2e-06 27.1 0.0 4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 GAO88379.1 - 5.7e-06 25.7 9.9 0.036 13.6 0.5 3.6 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 GAO88379.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Mito_carr PF00153.22 GAO88380.1 - 2.4e-67 222.7 5.4 8.2e-24 83.1 0.2 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein IBR PF01485.16 GAO88380.1 - 6.4e-22 77.1 44.3 1.3e-11 44.1 4.4 4.4 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 GAO88380.1 - 3.2e-06 26.8 39.0 9.1e-05 22.2 3.3 3.7 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4_2 PF13923.1 GAO88380.1 - 1.2e-05 25.1 6.5 1.2e-05 25.1 4.5 4.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO88380.1 - 0.00038 20.0 4.3 0.00038 20.0 3.0 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAO88380.1 - 0.011 15.4 1.2 0.011 15.4 0.8 3.6 3 0 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.3 GAO88380.1 - 0.021 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AceK PF06315.6 GAO88380.1 - 0.063 11.5 0.2 0.091 11.0 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-RING_5 PF14634.1 GAO88380.1 - 0.069 12.8 41.7 0.015 14.9 5.4 3.6 3 0 0 3 3 3 0 zinc-RING finger domain AAA PF00004.24 GAO88381.1 - 4.9e-38 130.3 0.1 1.8e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAO88381.1 - 5.5e-06 26.1 0.0 3.5e-05 23.5 0.0 2.5 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 GAO88381.1 - 1.4e-05 25.2 1.0 0.00011 22.3 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAO88381.1 - 5.5e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAO88381.1 - 0.00014 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAO88381.1 - 0.00045 20.2 2.9 0.022 14.7 0.0 3.3 2 1 2 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 GAO88381.1 - 0.00076 19.2 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAO88381.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAO88381.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO88381.1 - 0.0025 16.5 0.0 0.0041 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 GAO88381.1 - 0.0032 17.2 0.4 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 GAO88381.1 - 0.0034 16.5 0.1 0.0076 15.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 GAO88381.1 - 0.0043 16.6 0.0 0.022 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAO88381.1 - 0.0088 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAO88381.1 - 0.0091 16.8 0.9 0.11 13.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAO88381.1 - 0.012 15.0 0.1 0.12 11.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 GAO88381.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAO88381.1 - 0.027 14.4 0.6 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAO88381.1 - 0.082 12.5 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 GAO88381.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 GAO88381.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 GAO88381.1 - 0.1 12.1 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 GAO88381.1 - 0.14 11.3 0.1 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ENTH PF01417.15 GAO88382.1 - 2e-34 118.1 0.9 2.5e-23 82.3 0.0 2.7 2 1 1 3 3 3 2 ENTH domain UIM PF02809.15 GAO88382.1 - 0.00085 18.7 2.4 0.012 15.0 0.3 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.1 GAO88382.1 - 0.0045 16.3 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) DUF1675 PF07897.6 GAO88382.1 - 1.1 9.0 8.4 3.6 7.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Chorismate_bind PF00425.13 GAO88383.1 - 3.3e-89 298.6 0.0 5e-89 298.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 GAO88383.1 - 3.6e-16 59.4 0.0 4.7e-14 52.5 0.0 2.8 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region WD40 PF00400.27 GAO88383.1 - 1.2e-10 40.8 5.6 0.00082 19.1 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH PF08513.6 GAO88383.1 - 2e-06 27.3 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 GAO88383.1 - 0.00033 20.4 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF1751 PF08551.5 GAO88384.1 - 7.3e-32 109.6 2.5 1.6e-31 108.5 1.7 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 GAO88384.1 - 1e-06 28.8 6.5 6.6e-06 26.2 4.5 2.0 1 1 0 1 1 1 1 Rhomboid family L51_S25_CI-B8 PF05047.11 GAO88385.1 - 3.1e-21 74.8 0.0 4.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1 PF00133.17 GAO88386.1 - 8.3e-35 119.8 0.0 4.3e-23 81.1 0.0 3.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAO88386.1 - 3.6e-17 62.1 0.0 7.1e-11 41.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAO88386.1 - 1.1e-15 57.6 0.1 2.8e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 GAO88386.1 - 6.3e-07 28.8 0.0 1.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 GAO88386.1 - 0.027 13.1 0.0 0.2 10.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) Adeno_hexon_C PF03678.9 GAO88386.1 - 0.037 13.4 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Hexon, adenovirus major coat protein, C-terminal domain MMR_HSR1 PF01926.18 GAO88387.1 - 3.5e-07 30.1 0.0 2.5e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO88387.1 - 0.047 13.4 0.1 0.84 9.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 GAO88387.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ATPase-cat_bd PF12156.3 GAO88387.1 - 0.078 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase DUF258 PF03193.11 GAO88387.1 - 0.13 11.4 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Telomere_Sde2 PF13019.1 GAO88388.1 - 5.7e-67 224.4 0.7 5.7e-67 224.4 0.5 1.5 2 0 0 2 2 2 1 Telomere stability and silencing Rotamase_2 PF13145.1 GAO88388.1 - 0.065 13.8 0.7 0.14 12.8 0.5 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Apc4 PF12896.2 GAO88388.1 - 0.17 11.1 0.1 11 5.2 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Actino_peptide PF14408.1 GAO88388.1 - 0.3 11.0 2.8 0.96 9.4 2.0 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes S10_plectin PF03501.10 GAO88389.1 - 4.5e-42 141.8 0.2 5.5e-42 141.5 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 GAO88390.1 - 1.8e-24 86.3 0.1 2.4e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO88390.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO88390.1 - 0.0052 16.5 0.0 0.084 12.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 HIT PF01230.18 GAO88391.1 - 1.5e-23 83.1 0.0 2.1e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAO88391.1 - 1.8e-14 53.9 0.1 3.3e-14 53.0 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAO88391.1 - 7.1e-05 22.4 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 GAO88392.1 - 2.2e-44 150.7 0.0 3.7e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAO88392.1 - 5.4e-15 55.2 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAO88392.1 - 4.1e-10 39.7 0.0 7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UCH PF00443.24 GAO88393.1 - 1.6e-57 194.6 0.0 2.1e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DASH_Dam1 PF08653.5 GAO88393.1 - 3.5e-29 100.3 1.6 7.9e-29 99.2 1.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH_1 PF13423.1 GAO88393.1 - 1.1e-25 90.6 0.0 1.6e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ytp1 PF10355.4 GAO88394.1 - 1.6e-114 381.6 11.4 1.6e-114 381.6 7.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAO88394.1 - 1.4e-35 121.0 12.7 5.8e-34 115.8 3.6 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DLH PF01738.13 GAO88395.1 - 1.6e-31 109.3 0.0 1.8e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO88395.1 - 5.5e-05 22.9 0.0 8.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO88395.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO88395.1 - 0.059 13.2 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gaa1 PF04114.9 GAO88396.1 - 4.1e-82 276.5 6.3 3e-81 273.6 4.4 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 GAO88396.1 - 2.2e-05 24.5 5.6 2.2e-05 24.5 3.9 2.8 3 0 0 3 3 3 1 Rhomboid family YfhO PF09586.5 GAO88396.1 - 0.001 17.2 0.6 0.0017 16.5 0.4 1.3 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Pectate_lyase_3 PF12708.2 GAO88396.1 - 0.06 13.4 0.2 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Pectate lyase superfamily protein PCI PF01399.22 GAO88397.1 - 1.4e-09 38.1 0.0 3.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain GrpE PF01025.14 GAO88397.1 - 0.014 14.9 0.6 0.024 14.1 0.4 1.4 1 0 0 1 1 1 0 GrpE Methyltransf_23 PF13489.1 GAO88398.1 - 1.9e-14 53.7 0.1 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88398.1 - 2.7e-14 53.0 0.0 4.3e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88398.1 - 1.1e-12 48.5 0.0 1.8e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO88398.1 - 1.7e-12 47.6 0.0 3.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO88398.1 - 3.1e-10 40.3 0.0 6.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO88398.1 - 5.4e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO88398.1 - 1e-05 25.5 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO88398.1 - 4.5e-05 22.9 0.0 0.00018 20.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAO88398.1 - 8.3e-05 21.8 0.0 0.00029 20.0 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 GAO88398.1 - 0.002 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.5 GAO88398.1 - 0.031 13.8 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TPMT PF05724.6 GAO88398.1 - 0.041 13.3 0.0 0.074 12.4 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 GAO88398.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 GAO88398.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NAD_binding_10 PF13460.1 GAO88399.1 - 7.1e-19 68.5 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO88399.1 - 3.2e-15 56.2 0.0 8.5e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO88399.1 - 1.2e-14 54.0 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAO88399.1 - 3.4e-13 48.9 0.0 8.1e-13 47.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAO88399.1 - 7.5e-08 31.5 0.0 8.4e-07 28.1 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAO88399.1 - 3.3e-06 26.1 0.2 0.00021 20.3 0.2 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 GAO88399.1 - 0.0022 17.9 0.0 0.029 14.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88399.1 - 0.012 15.2 0.0 4.4 6.9 0.0 2.5 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 GAO88399.1 - 0.016 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDE_Tnp_1_3 PF13612.1 GAO88399.1 - 0.022 14.5 0.0 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain Saccharop_dh PF03435.13 GAO88399.1 - 0.025 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase HEM4 PF02602.10 GAO88400.1 - 2.3e-32 112.1 0.0 6.6e-32 110.5 0.0 1.7 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 GAO88401.1 - 9.2e-75 251.1 0.0 1.1e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88401.1 - 3.4e-32 111.5 0.0 4.4e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO88401.1 - 0.00054 19.0 0.0 0.0015 17.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAO88401.1 - 0.0022 17.0 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO88401.1 - 0.013 15.2 0.1 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO88401.1 - 0.06 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 GAO88402.1 - 1.5e-70 237.2 0.0 2.5e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAO88402.1 - 4.6e-24 83.8 0.0 6.7e-23 80.0 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 GAO88402.1 - 7.2e-18 63.8 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 GAO88402.1 - 1.2e-16 60.9 0.0 2.9e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 GAO88402.1 - 3.9e-09 36.0 0.0 8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 GAO88402.1 - 0.29 11.1 0.7 0.8 9.7 0.5 1.7 1 0 0 1 1 1 0 Testis-expressed 12 Kinesin PF00225.18 GAO88403.1 - 1.4e-84 283.6 0.4 1.4e-84 283.6 0.3 2.1 2 0 0 2 2 2 1 Kinesin motor domain TPR_12 PF13424.1 GAO88403.1 - 0.0076 16.1 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NTR PF01759.16 GAO88403.1 - 0.063 12.8 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 UNC-6/NTR/C345C module PLAC9 PF15205.1 GAO88403.1 - 0.59 10.4 3.8 6.2 7.1 0.0 2.6 1 1 1 2 2 2 0 Placenta-specific protein 9 AIM24 PF01987.12 GAO88404.1 - 2.8e-49 167.4 0.0 3.7e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_tran PF00005.22 GAO88405.1 - 4e-35 121.0 0.0 8.8e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAO88405.1 - 1.1e-34 120.1 13.6 1.5e-34 119.6 9.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 GAO88405.1 - 1.6e-07 31.6 0.0 0.0033 17.4 0.0 2.9 2 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 GAO88405.1 - 8.6e-05 21.8 0.1 0.063 12.5 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAO88405.1 - 0.00013 22.7 0.0 0.00038 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO88405.1 - 0.0003 20.9 0.1 0.0021 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO88405.1 - 0.00032 20.7 0.1 0.0025 17.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAO88405.1 - 0.00097 19.0 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAO88405.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO88405.1 - 0.0045 16.1 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 GAO88405.1 - 0.0093 14.5 0.0 0.1 11.1 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 GAO88405.1 - 0.01 16.1 0.0 0.042 14.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 GAO88405.1 - 0.013 15.0 0.0 0.053 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 GAO88405.1 - 0.014 15.7 0.3 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAO88405.1 - 0.014 14.8 0.0 0.057 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 GAO88405.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 GAO88405.1 - 0.023 14.6 0.0 0.17 11.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF2847 PF11009.3 GAO88405.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AAA PF00004.24 GAO88405.1 - 0.026 14.7 0.0 0.18 11.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAO88405.1 - 0.075 12.9 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 GAO88405.1 - 0.093 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 GAO88405.1 - 0.31 10.9 2.4 0.85 9.5 0.3 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Vac14_Fig4_bd PF11916.3 GAO88407.1 - 3.1e-84 280.6 7.7 3.1e-84 280.6 5.3 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 GAO88407.1 - 1.5e-45 153.5 0.0 1.2e-42 144.2 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 GAO88407.1 - 1.8e-09 36.8 1.5 0.00021 21.0 0.0 6.5 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 GAO88407.1 - 1.4e-08 34.9 3.9 0.0013 19.1 0.0 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 GAO88407.1 - 5.3e-08 33.0 0.8 0.0086 16.3 0.0 5.5 5 2 0 5 5 5 2 HEAT repeats Ipi1_N PF12333.3 GAO88407.1 - 0.027 14.4 0.0 1.1 9.2 0.0 3.5 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 GAO88407.1 - 0.043 13.6 0.0 13 5.7 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.18 GAO88408.1 - 5.1e-66 222.5 0.0 6.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 GAO88408.1 - 7.8e-27 94.3 1.8 2.6e-25 89.3 1.0 2.3 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 GAO88408.1 - 3.3e-13 49.2 0.0 1.1e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAO88408.1 - 8.7e-06 24.7 0.0 3.1e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 GAO88408.1 - 0.0018 18.1 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 GAO88409.1 - 2.1e-23 81.8 0.6 5.2e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein zf-C2H2_jaz PF12171.3 GAO88410.1 - 2.3e-09 37.0 4.3 3.9e-09 36.3 2.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAO88410.1 - 0.0077 16.3 0.9 0.012 15.7 0.6 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAO88410.1 - 0.011 15.9 2.5 0.019 15.1 1.7 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAO88410.1 - 0.013 15.4 0.6 0.023 14.6 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.7 GAO88410.1 - 0.047 13.2 0.5 0.078 12.5 0.4 1.4 1 0 0 1 1 1 0 U1 zinc finger Ribosomal_L2 PF00181.18 GAO88410.1 - 0.13 12.2 0.7 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain zf-C2H2_4 PF13894.1 GAO88410.1 - 0.15 12.4 0.5 0.37 11.2 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Aconitase PF00330.15 GAO88411.1 - 2.3e-176 586.8 0.0 4.8e-176 585.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAO88411.1 - 4.2e-45 153.0 0.0 7.4e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 GAO88412.1 - 2.5e-25 89.2 1.8 3.3e-25 88.8 1.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO88412.1 - 8.7e-06 25.4 0.6 1.3e-05 24.7 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO88412.1 - 0.00019 21.1 0.5 0.00032 20.4 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 GAO88413.1 - 7.2e-201 667.7 0.0 8.2e-201 667.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 GAO88413.1 - 0.0079 15.7 0.5 0.028 13.9 0.1 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Ribosomal_S17 PF00366.15 GAO88414.1 - 0.004 17.1 0.3 0.0091 16.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 WD40 PF00400.27 GAO88415.1 - 7.4e-79 257.0 11.9 2.4e-12 46.2 0.1 7.6 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAO88415.1 - 1.5e-07 29.9 5.6 0.00087 17.5 0.1 4.0 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO88415.1 - 0.00036 19.4 0.0 1.2 7.7 0.0 3.4 2 1 0 2 2 2 2 Nup133 N terminal like HEAT_2 PF13646.1 GAO88416.1 - 2.7e-06 27.5 0.6 0.45 10.8 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats CLASP_N PF12348.3 GAO88416.1 - 1e-05 25.0 0.0 9.9e-05 21.7 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.15 GAO88416.1 - 7.4e-05 21.2 0.0 1.1 7.4 0.0 3.0 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 GAO88416.1 - 0.00014 21.6 0.9 25 5.3 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat IncA PF04156.9 GAO88416.1 - 0.00025 20.7 0.7 0.00025 20.7 0.5 1.9 2 0 0 2 2 2 1 IncA protein MMS19_N PF14500.1 GAO88416.1 - 0.00037 19.8 0.9 0.015 14.6 0.4 2.7 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II FTCD_N PF07837.7 GAO88416.1 - 0.01 15.3 0.4 0.078 12.4 0.0 2.5 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain Proteasom_PSMB PF10508.4 GAO88416.1 - 0.03 12.6 0.1 0.18 10.0 0.1 2.1 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit APG6 PF04111.7 GAO88416.1 - 0.034 13.1 15.8 0.008 15.2 7.2 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 GAO88416.1 - 0.044 11.1 7.4 0.1 9.9 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PhoU PF01895.14 GAO88416.1 - 0.12 12.8 1.5 1.1 9.8 0.1 3.0 3 0 0 3 3 3 0 PhoU domain ERCC4 PF02732.10 GAO88416.1 - 0.12 12.0 0.3 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 ERCC4 domain G-gamma PF00631.17 GAO88416.1 - 0.34 10.6 1.7 1.8 8.4 0.7 2.6 2 0 0 2 2 2 0 GGL domain TPR_MLP1_2 PF07926.7 GAO88416.1 - 1.7 8.4 14.4 0.44 10.2 3.5 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1675 PF07897.6 GAO88416.1 - 3.1 7.5 6.6 0.71 9.6 2.2 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1675) Ribosomal_L7Ae PF01248.21 GAO88417.1 - 2.9e-23 81.1 0.7 5.1e-23 80.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clat_adaptor_s PF01217.15 GAO88418.1 - 2.3e-43 147.2 0.0 5.8e-43 146.0 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 GAO88419.1 - 4.2e-18 65.3 0.0 5.9e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO88419.1 - 6.2e-05 22.8 0.0 0.00082 19.2 0.0 2.2 1 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 GAO88419.1 - 0.00029 20.3 0.0 0.0042 16.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAO88419.1 - 0.0005 19.3 0.0 0.00082 18.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAO88419.1 - 0.003 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAO88419.1 - 0.0042 16.2 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_29 PF13555.1 GAO88419.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 GAO88419.1 - 0.025 13.7 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 GAO88419.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 GAO88419.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 GAO88420.1 - 2e-54 179.6 20.8 2.7e-09 36.5 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 GAO88420.1 - 2.2e-08 33.6 0.1 4.7e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO88420.1 - 2e-07 30.4 0.1 5e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 GAO88420.1 - 1.2e-05 23.6 5.2 0.64 8.0 0.1 4.8 3 2 2 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAO88420.1 - 0.00011 21.9 0.4 0.54 10.0 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.13 GAO88421.1 - 5.2e-61 205.7 0.0 9.4e-61 204.9 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 GAO88421.1 - 0.0021 17.7 7.5 0.0036 16.9 5.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAO88421.1 - 0.0049 16.1 2.4 0.016 14.5 1.8 1.8 1 1 1 2 2 2 1 PHD-finger DUF2424 PF10340.4 GAO88421.1 - 0.23 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Nuc_sug_transp PF04142.10 GAO88423.1 - 2.9e-67 226.3 4.3 5.7e-67 225.3 3.0 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.11 GAO88423.1 - 1.3e-42 146.1 0.0 4.4e-41 141.1 0.0 2.3 1 1 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 GAO88423.1 - 3.3e-26 91.7 0.1 6.7e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAO88423.1 - 6.1e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EmrE PF13536.1 GAO88423.1 - 5.7e-07 29.7 13.1 3.2e-06 27.2 1.0 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Helicase_C PF00271.26 GAO88423.1 - 3.6e-06 26.7 0.0 9.6e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UAA PF08449.6 GAO88423.1 - 0.0001 21.3 4.8 0.00022 20.2 3.3 1.5 1 1 0 1 1 1 1 UAA transporter family AAA_22 PF13401.1 GAO88423.1 - 0.0088 16.1 0.0 0.029 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAO88423.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAO88423.1 - 0.17 10.7 0.0 0.37 9.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TPT PF03151.11 GAO88423.1 - 0.26 10.9 18.7 0.25 10.9 5.8 2.6 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 GAO88423.1 - 0.76 9.8 23.1 0.023 14.7 4.6 2.5 2 0 0 2 2 2 0 EamA-like transporter family LRR_1 PF00560.28 GAO88424.1 - 0.00014 21.4 1.8 0.42 10.8 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 GAO88424.1 - 0.00018 21.2 1.5 4.5 7.6 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 GAO88424.1 - 0.02 14.4 6.5 0.097 12.3 0.6 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF3215 PF11503.3 GAO88424.1 - 0.076 12.6 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) LRR_8 PF13855.1 GAO88424.1 - 0.4 10.4 6.0 4.2 7.1 0.8 3.5 2 1 1 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 GAO88424.1 - 0.56 10.6 3.6 19 6.0 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat Acid_PPase PF12689.2 GAO88425.1 - 2.7e-70 235.3 0.0 3.3e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 GAO88425.1 - 0.03 14.5 1.0 0.4 10.8 0.1 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 GAO88426.1 - 6e-13 47.6 12.4 0.0013 18.1 1.6 4.2 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAO88426.1 - 0.02 14.4 2.0 0.02 14.4 1.4 3.8 3 2 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF1168 PF06658.7 GAO88426.1 - 0.049 13.1 0.2 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) TPR_MLP1_2 PF07926.7 GAO88427.1 - 4.8e-30 104.0 31.6 4.8e-30 104.0 21.9 15.5 6 3 7 14 14 14 6 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 GAO88427.1 - 0.00057 19.7 32.6 0.0011 18.8 12.6 16.3 7 3 8 16 16 16 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Surfac_D-trimer PF09006.6 GAO88427.1 - 0.2 11.4 11.8 1.5 8.6 0.0 6.1 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation TFIIE_beta PF02186.10 GAO88428.1 - 3.6e-06 26.8 0.1 1.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain DHBP_synthase PF00926.14 GAO88429.1 - 2.3e-72 242.3 0.0 1.4e-71 239.8 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.2 GAO88430.1 - 3.4e-07 29.8 0.1 7.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO88430.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Gag_p12 PF01141.13 GAO88430.1 - 1.3 9.2 6.5 1.2 9.3 3.0 2.1 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Pkinase PF00069.20 GAO88431.1 - 8.6e-51 172.5 0.0 1.6e-49 168.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88431.1 - 8.9e-19 67.5 0.0 6.7e-18 64.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO88431.1 - 2.2e-08 33.4 0.0 3.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO88431.1 - 0.002 17.9 0.1 0.047 13.4 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO88431.1 - 0.067 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 GAO88432.1 - 2e-49 166.6 0.0 2.4e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO88432.1 - 0.00033 20.4 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO88432.1 - 0.00039 20.2 0.3 0.00069 19.4 0.2 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAO88432.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain A_deaminase PF00962.17 GAO88433.1 - 6.4e-43 146.9 0.0 1.5e-42 145.6 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Nucleos_tra2_C PF07662.8 GAO88434.1 - 1.5e-71 240.1 0.7 1.5e-71 240.1 0.5 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 GAO88434.1 - 4.8e-25 87.6 2.6 4.8e-25 87.6 1.8 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 GAO88434.1 - 0.011 15.6 9.9 0.011 15.6 6.8 3.7 3 0 0 3 3 3 0 Nucleoside recognition ATG2_CAD PF13329.1 GAO88435.1 - 2.5e-51 173.3 0.2 6.9e-51 171.9 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 GAO88435.1 - 1.2e-25 89.5 0.0 4.3e-25 87.7 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain adh_short PF00106.20 GAO88437.1 - 8.7e-12 45.2 0.1 1.3e-10 41.4 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88437.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 GAO88437.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CN_hydrolase PF00795.17 GAO88439.1 - 4.3e-33 114.2 0.0 1.1e-32 112.9 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase PA PF02225.17 GAO88439.1 - 0.0048 16.5 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 2 PA domain Ribosomal_L31e PF01198.14 GAO88440.1 - 4.1e-38 128.9 2.2 5.4e-38 128.5 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Ran_BP1 PF00638.13 GAO88442.1 - 3.1e-16 59.5 0.0 6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 GAO88442.1 - 8.5e-07 29.1 90.0 3.6e-06 27.1 26.4 12.2 3 3 5 8 8 8 2 Nucleoporin FG repeat region NUP50 PF08911.6 GAO88442.1 - 0.00043 20.5 5.3 0.00043 20.5 3.7 8.7 9 2 0 9 9 9 2 NUP50 (Nucleoporin 50 kDa) Pectate_lyase_3 PF12708.2 GAO88443.1 - 4.4e-79 265.7 21.0 1.7e-56 191.8 6.6 3.5 3 0 0 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAO88443.1 - 1e-07 31.3 3.4 0.0065 15.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase SCP2 PF02036.12 GAO88444.1 - 5.1e-26 90.9 0.4 6.1e-26 90.6 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAO88444.1 - 6.6e-08 32.5 0.1 8.2e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SNF2_N PF00176.18 GAO88445.1 - 3.1e-71 239.6 0.0 5.4e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO88445.1 - 1.7e-10 40.5 0.0 4.9e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAO88445.1 - 7.4e-09 35.4 5.1 1.5e-08 34.4 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO88445.1 - 1.1e-08 34.6 2.8 2.1e-08 33.6 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO88445.1 - 4.2e-07 29.6 3.9 8e-07 28.7 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 GAO88445.1 - 5.3e-07 29.2 0.0 1.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAO88445.1 - 7.3e-07 29.1 0.3 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 GAO88445.1 - 1.2e-06 28.0 3.4 3e-06 26.8 2.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO88445.1 - 9.5e-06 25.1 4.1 9.5e-06 25.1 2.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAO88445.1 - 9.6e-05 22.1 5.8 0.00021 21.0 4.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAO88445.1 - 0.00021 20.9 1.5 0.00047 19.8 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 GAO88445.1 - 0.0006 19.3 3.6 0.0017 17.9 2.5 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Tho2 PF11262.3 GAO88445.1 - 0.18 10.7 3.5 0.45 9.5 2.4 1.6 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-MIZ PF02891.15 GAO88445.1 - 0.63 9.6 4.5 1.3 8.5 3.2 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Ras PF00071.17 GAO88446.1 - 2.9e-41 140.5 0.0 4.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO88446.1 - 4.2e-08 33.7 0.0 1.2e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PDZ PF00595.19 GAO88446.1 - 1.3e-07 31.7 0.2 2.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 GAO88446.1 - 2.7e-06 27.1 0.0 7.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Arf PF00025.16 GAO88446.1 - 8e-06 25.2 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GRASP55_65 PF04495.9 GAO88446.1 - 0.0031 17.4 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RhoGEF PF00621.15 GAO88447.1 - 1.4e-05 25.0 0.0 4.9e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain SBDS PF01172.13 GAO88448.1 - 6.8e-26 89.8 0.0 7.8e-26 89.7 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UDG PF03167.14 GAO88449.1 - 1.2e-18 67.0 0.0 2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF605 PF04652.11 GAO88449.1 - 4.6 6.5 11.4 6 6.1 7.9 1.1 1 0 0 1 1 1 0 Vta1 like NAD_binding_6 PF08030.7 GAO88450.1 - 7.5e-24 84.4 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO88450.1 - 9.4e-22 76.8 0.0 2.2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAO88450.1 - 2.1e-17 63.3 9.4 2.1e-17 63.3 6.5 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAO88450.1 - 9.7e-05 22.4 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAO88450.1 - 0.15 12.6 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NRDE-2 PF08424.5 GAO88451.1 - 4.2e-100 334.7 0.1 4.2e-100 334.7 0.0 2.8 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 GAO88451.1 - 0.0024 18.3 7.2 7.3 7.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO88451.1 - 0.027 15.1 0.3 0.32 11.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BP28CT PF08146.7 GAO88452.1 - 6.6e-46 155.8 0.1 3.9e-45 153.3 0.1 2.5 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 GAO88452.1 - 2.8e-31 107.9 8.3 2e-30 105.2 0.3 5.1 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 GAO88452.1 - 4.4e-12 46.1 5.7 0.0004 20.5 0.0 5.9 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 GAO88452.1 - 1.9e-06 27.4 6.3 0.00053 19.8 0.1 6.5 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 GAO88452.1 - 0.0026 18.2 0.4 0.0026 18.2 0.2 8.1 8 1 1 9 9 9 1 HEAT-like repeat Arm PF00514.18 GAO88452.1 - 0.079 12.8 3.3 1.4 8.8 0.1 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FAD_binding_4 PF01565.18 GAO88453.1 - 1.3e-27 95.9 0.0 2.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BRK PF07533.11 GAO88453.1 - 0.0067 15.8 0.0 0.047 13.1 0.0 2.4 2 0 0 2 2 2 1 BRK domain MFS_1 PF07690.11 GAO88454.1 - 3.7e-32 111.4 27.9 4.6e-32 111.0 16.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO88454.1 - 2.5e-11 42.8 3.6 2.5e-11 42.8 2.5 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter Bul1_N PF04425.7 GAO88454.1 - 8.9e-07 27.8 1.6 6.3e-06 25.0 0.2 2.1 1 1 0 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.24 GAO88454.1 - 1.6e-05 24.7 0.0 4.3e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 GAO88454.1 - 0.00033 19.9 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus DUF1228 PF06779.9 GAO88454.1 - 0.0059 16.5 1.6 0.21 11.6 0.3 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DAO PF01266.19 GAO88455.1 - 2.2e-29 102.4 0.9 3.5e-29 101.8 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 GAO88455.1 - 2.3e-09 36.3 0.1 0.00015 20.5 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain NAD_binding_8 PF13450.1 GAO88455.1 - 0.015 15.3 1.6 0.02 14.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO88455.1 - 0.024 14.4 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO88455.1 - 0.11 12.5 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO88455.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 GAO88456.1 - 8.6e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.1 GAO88456.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 HTH domain CPSF_A PF03178.10 GAO88457.1 - 2.9e-101 338.7 0.0 7.7e-100 334.0 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 GAO88457.1 - 5e-69 232.7 0.0 7.5e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 GAO88457.1 - 0.0048 16.5 0.0 1.6 8.4 0.0 3.2 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, N-terminal ubiquitin PF00240.18 GAO88458.1 - 1.2e-19 69.4 0.1 2e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAO88458.1 - 7.6e-09 35.1 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 GAO88458.1 - 8.8e-09 34.9 0.0 8.8e-09 34.9 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 GAO88458.1 - 1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAO88458.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 GAO88458.1 - 0.0041 17.6 0.0 0.0084 16.6 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 GAO88458.1 - 0.014 15.6 0.3 0.045 14.0 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain EMP70 PF02990.11 GAO88459.1 - 2.8e-151 504.5 0.0 9.8e-151 502.7 0.0 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Sulfatase PF00884.18 GAO88460.1 - 8.3e-61 205.8 0.1 1.2e-60 205.3 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 GAO88460.1 - 6.7e-22 77.0 0.6 1.4e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 GAO88460.1 - 2e-09 37.2 1.8 2.6e-07 30.2 1.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 GAO88460.1 - 0.0027 17.9 0.0 0.0063 16.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 GAO88460.1 - 0.0061 15.0 0.0 0.0069 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 GAO88460.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 GAO88460.1 - 0.19 11.0 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily CN_hydrolase PF00795.17 GAO88461.1 - 7.8e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lactamase_B_2 PF12706.2 GAO88463.1 - 3.1e-12 46.4 0.0 4.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO88463.1 - 0.0018 18.0 0.1 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ice_nucleation PF00818.12 GAO88463.1 - 9.6 5.7 9.0 2.9 7.3 4.0 1.8 2 0 0 2 2 2 0 Ice nucleation protein repeat Pyridoxal_deC PF00282.14 GAO88464.1 - 1e-76 257.8 0.0 1.4e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PALP PF00291.20 GAO88467.1 - 2.6e-34 118.8 0.1 3.3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBDS_C PF09377.5 GAO88468.1 - 1.1e-52 176.9 0.0 1.7e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 GAO88468.1 - 5.1e-26 90.2 0.1 8.7e-26 89.5 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein EnY2 PF10163.4 GAO88468.1 - 0.028 14.3 0.5 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Transcription factor e(y)2 Peptidase_S10 PF00450.17 GAO88469.1 - 3.6e-131 438.1 0.1 4.4e-131 437.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 GAO88469.1 - 9.3e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 GAO88469.1 - 0.00053 19.9 0.0 0.013 15.3 0.0 2.7 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO88469.1 - 0.12 12.0 0.0 0.74 9.5 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 GAO88470.1 - 9.5e-42 141.7 1.2 1.5e-41 141.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAO88470.1 - 0.00078 18.1 0.0 0.00095 17.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 GAO88470.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) HHH_6 PF14579.1 GAO88470.1 - 0.079 13.0 0.1 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif peroxidase PF00141.18 GAO88472.1 - 2.5e-48 164.5 0.0 3.8e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Iso_dh PF00180.15 GAO88473.1 - 5.4e-111 370.9 0.0 6.1e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HTH_psq PF05225.11 GAO88474.1 - 3.2e-06 26.5 0.5 6.4e-06 25.6 0.1 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 GAO88474.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 GAO88474.1 - 0.023 14.3 0.1 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF3801 PF12687.2 GAO88474.1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) HTH_28 PF13518.1 GAO88474.1 - 0.044 13.7 0.1 0.09 12.8 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.8 GAO88474.1 - 0.051 12.9 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MerR_1 PF13411.1 GAO88474.1 - 0.099 12.4 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 MerR HTH family regulatory protein HTH_8 PF02954.14 GAO88474.1 - 0.13 11.8 0.1 0.45 10.0 0.0 1.9 2 1 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.1 GAO88474.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ATPgrasp_TupA PF14305.1 GAO88475.1 - 0.043 13.1 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 TupA-like ATPgrasp TRAM1 PF08390.6 GAO88475.1 - 0.13 11.7 0.2 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 TRAM1-like protein DUF3506 PF12014.3 GAO88476.1 - 4.3e-11 42.7 0.0 1.1e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) HET PF06985.6 GAO88476.1 - 1.7e-07 31.4 0.6 2.1e-06 27.9 0.0 2.5 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 GAO88477.1 - 2.8e-36 123.7 7.7 3.9e-15 55.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88477.1 - 2.2e-26 90.3 7.1 1.5e-07 30.8 0.2 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 GAO88477.1 - 8.5e-25 86.2 5.0 6e-08 32.6 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO88477.1 - 1e-24 86.4 2.2 1e-11 44.9 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88477.1 - 2.2e-23 79.9 1.6 3.3e-05 23.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Plug PF07715.10 GAO88477.1 - 0.15 12.4 0.9 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 TonB-dependent Receptor Plug Domain Ank_2 PF12796.2 GAO88478.1 - 3.1e-26 91.5 2.2 8.1e-15 54.9 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88478.1 - 1.9e-21 74.7 8.0 1.1e-08 34.4 0.1 5.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAO88478.1 - 3.7e-19 68.6 1.1 3e-06 27.6 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO88478.1 - 3.8e-18 65.0 9.9 2.6e-08 33.8 0.6 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88478.1 - 1.1e-15 56.1 0.1 0.00011 22.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Shigella_OspC PF06128.6 GAO88478.1 - 0.012 15.1 0.4 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Shigella flexneri OspC protein Ribosomal_S6 PF01250.12 GAO88478.1 - 0.022 14.6 0.1 1.3 8.8 0.0 2.7 1 1 2 3 3 3 0 Ribosomal protein S6 DUF4367 PF14285.1 GAO88478.1 - 0.098 11.9 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) H_lectin PF09458.5 GAO88479.1 - 0.00086 18.9 0.1 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 H-type lectin domain DUF4216 PF13952.1 GAO88480.1 - 0.041 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) SprA-related PF12118.3 GAO88481.1 - 4.5 6.4 24.4 4.7 6.4 16.9 1.0 1 0 0 1 1 1 0 SprA-related family TPR_11 PF13414.1 GAO88482.1 - 5.7e-14 51.5 7.5 7.1e-10 38.3 0.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAO88482.1 - 4.5e-10 38.6 10.3 0.00016 21.1 0.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO88482.1 - 1.6e-07 30.6 11.4 0.00022 20.8 0.6 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAO88482.1 - 0.00034 21.1 4.2 0.0013 19.3 0.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAO88482.1 - 0.0011 19.2 1.9 0.0011 19.2 1.3 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO88482.1 - 0.0017 18.4 1.4 0.0035 17.4 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 GAO88482.1 - 0.028 12.9 0.2 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_12 PF13424.1 GAO88482.1 - 0.03 14.2 5.0 0.76 9.7 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO88482.1 - 0.032 14.8 4.5 0.055 14.1 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAO88482.1 - 0.051 13.7 4.0 0.1 12.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 GAO88482.1 - 0.35 10.7 1.9 0.54 10.1 0.1 2.1 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus TPR_8 PF13181.1 GAO88482.1 - 0.7 9.8 7.5 34 4.5 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO88482.1 - 0.92 10.1 3.8 11 6.7 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.5 GAO88482.1 - 7.8 5.9 19.2 0.32 10.5 2.8 2.2 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Glyco_hydro_10 PF00331.15 GAO88483.1 - 8e-103 343.8 0.7 9.3e-103 343.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 GAO88483.1 - 6.2e-15 54.5 13.5 6.2e-15 54.5 9.3 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2841 PF11001.3 GAO88484.1 - 7.3e-46 155.1 0.2 1e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) PDZ_1 PF12812.2 GAO88485.1 - 8.9e-54 179.3 0.0 3.9e-34 116.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 GAO88485.1 - 2.9e-14 53.0 0.0 9.8e-14 51.3 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 GAO88485.1 - 5.7e-13 48.5 0.0 2.1e-05 24.3 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 GAO88485.1 - 1.6e-11 44.1 0.0 7.5e-05 22.8 0.0 4.1 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 GAO88485.1 - 0.0003 20.5 0.4 0.12 12.1 0.1 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain Adeno_hexon PF01065.14 GAO88485.1 - 0.27 10.0 7.9 0.43 9.3 5.5 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain DUF4557 PF15101.1 GAO88485.1 - 0.37 10.5 8.8 0.8 9.5 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 GAO88485.1 - 2.2 8.1 6.4 6.6 6.5 4.5 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 GAO88485.1 - 3.5 7.2 8.8 7.5 6.1 6.1 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Enkurin PF13864.1 GAO88486.1 - 0.03 14.5 0.7 0.054 13.7 0.5 1.5 1 0 0 1 1 1 0 Calmodulin-binding INCENP_ARK-bind PF03941.10 GAO88487.1 - 2.3e-20 72.1 0.8 2.3e-20 72.1 0.6 2.4 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region CAF-1_p150 PF11600.3 GAO88487.1 - 0.0021 17.4 32.8 0.0021 17.4 22.7 6.4 4 2 2 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Reticulon PF02453.12 GAO88488.1 - 4.5e-40 137.0 3.2 6.2e-40 136.5 2.2 1.2 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.4 GAO88488.1 - 0.13 11.4 0.4 0.23 10.7 0.3 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DNA_topoisoIV PF00521.15 GAO88490.1 - 1.2e-137 459.3 0.0 2.8e-137 458.0 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAO88490.1 - 2.4e-34 118.0 2.2 6.8e-34 116.5 1.5 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 GAO88490.1 - 2.3e-14 53.1 0.0 1.4e-13 50.6 0.0 2.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 GAO88490.1 - 4e-11 42.5 0.0 1.1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 GAO88491.1 - 6.5e-49 166.2 0.0 2.2e-48 164.5 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Leu_zip PF15294.1 GAO88491.1 - 0.00085 18.5 3.3 0.00085 18.5 2.3 3.4 3 1 0 4 4 4 1 Leucine zipper USP8_interact PF08941.5 GAO88491.1 - 3.6 6.8 6.4 26 4.0 0.5 3.2 2 1 1 3 3 3 0 USP8 interacting Acetyltransf_3 PF13302.1 GAO88492.1 - 0.47 10.6 2.3 7.6 6.6 1.6 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 GAO88493.1 - 6.9e-30 104.1 8.8 9.9e-30 103.6 6.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88493.1 - 1.1e-23 84.2 3.2 1.4e-23 83.9 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88493.1 - 3.2e-14 52.9 5.8 4.6e-14 52.4 4.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO88493.1 - 0.021 14.2 1.0 0.028 13.8 0.7 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kri1 PF05178.7 GAO88493.1 - 0.15 12.3 0.1 0.41 10.9 0.0 1.6 2 0 0 2 2 2 0 KRI1-like family Patatin PF01734.17 GAO88494.1 - 2.9e-26 92.6 0.0 6.8e-26 91.4 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase BTB PF00651.26 GAO88495.1 - 0.00073 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 GAO88496.1 - 1.5e-27 96.2 26.9 1.5e-27 96.2 18.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAO88497.1 - 1.1e-07 31.5 12.4 1.9e-07 30.8 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO88497.1 - 7.8e-06 24.7 0.0 1.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain META PF03724.11 GAO88497.1 - 0.15 11.8 1.2 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 META domain Glyco_hydro_92 PF07971.7 GAO88498.1 - 5.1e-174 579.6 0.0 6.3e-174 579.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Ferric_reduct PF01794.14 GAO88499.1 - 3.6e-20 72.3 10.9 3.6e-20 72.3 7.5 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO88499.1 - 1.2e-16 61.0 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO88499.1 - 1.2e-11 44.4 0.0 3.7e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 GAO88499.1 - 0.001 19.6 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Sulfotransfer_3 PF13469.1 GAO88500.1 - 0.031 15.2 0.9 0.048 14.5 0.6 1.3 1 0 0 1 1 1 0 Sulfotransferase family DUF3140 PF11338.3 GAO88502.1 - 1.5e-32 111.5 0.3 2.5e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) MFS_1 PF07690.11 GAO88502.1 - 6.7e-28 97.4 19.8 6.7e-28 97.4 13.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO88502.1 - 0.00027 19.3 1.1 0.00045 18.5 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phosducin PF02114.11 GAO88502.1 - 0.05 12.3 0.4 0.64 8.7 0.1 2.1 2 0 0 2 2 2 0 Phosducin DUF4605 PF15378.1 GAO88502.1 - 5 6.8 8.3 1.4 8.6 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4605) Med4 PF10018.4 GAO88503.1 - 1.2e-55 187.8 0.5 1.2e-55 187.8 0.4 1.7 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Laminin_I PF06008.9 GAO88503.1 - 0.031 13.6 0.4 0.11 11.7 0.2 2.1 2 1 0 2 2 2 0 Laminin Domain I DUF4611 PF15387.1 GAO88503.1 - 0.063 13.4 0.6 0.19 11.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HAUS5 PF14817.1 GAO88503.1 - 0.11 11.0 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 SnoaL PF07366.7 GAO88504.1 - 2.8e-06 26.9 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAO88504.1 - 0.00039 20.7 0.0 0.00078 19.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain CFEM PF05730.6 GAO88507.1 - 1.5e-12 47.1 10.9 2.7e-12 46.3 7.6 1.4 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.22 GAO88508.1 - 1.4e-61 204.1 4.8 1.5e-20 72.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 GAO88508.1 - 9.3 5.8 7.3 5.5 6.6 0.7 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif UQ_con PF00179.21 GAO88510.1 - 1.2e-43 147.9 0.0 1.4e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RTA1 PF04479.8 GAO88511.1 - 4.7e-47 160.3 0.2 7.4e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 GAO88512.1 - 9.2e-10 38.2 8.8 1.7e-09 37.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO88512.1 - 0.00013 20.7 0.1 0.00019 20.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_4 PF07993.7 GAO88513.1 - 3.5e-34 117.8 0.0 4.5e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAO88513.1 - 2.7e-05 23.1 0.0 3.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Cation_efflux PF01545.16 GAO88514.1 - 2.3e-52 177.8 14.1 2.3e-52 177.8 9.8 3.0 3 1 0 3 3 3 1 Cation efflux family Zip PF02535.17 GAO88514.1 - 0.067 12.1 68.5 0.062 12.3 3.2 4.6 2 1 2 4 4 4 0 ZIP Zinc transporter Glyco_trans_1_4 PF13692.1 GAO88515.1 - 5.5e-27 94.5 0.0 1e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAO88515.1 - 2.8e-05 24.2 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAO88515.1 - 7.7e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain zf-TFIIIC PF12660.2 GAO88516.1 - 1.3e-30 105.2 0.9 2.8e-30 104.1 0.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex G-gamma PF00631.17 GAO88516.1 - 0.13 12.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 GGL domain zinc_ribbon_2 PF13240.1 GAO88516.1 - 0.2 11.1 5.4 0.75 9.3 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain Thiolase_N PF00108.18 GAO88517.1 - 6.7e-96 320.3 0.4 9.6e-96 319.8 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO88517.1 - 6.1e-38 129.0 1.0 6.1e-38 129.0 0.7 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAO88517.1 - 1.1e-05 25.0 1.4 1.1e-05 25.0 1.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAO88517.1 - 1.4 8.6 6.1 2.8 7.6 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 GAO88518.1 - 2.3e-51 172.9 0.0 2.6e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO88518.1 - 1.1e-05 25.1 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO88518.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 GAO88519.1 - 6.4e-112 373.5 0.0 1.5e-111 372.3 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 GAO88519.1 - 0.01 15.5 5.0 0.01 15.5 3.5 6.7 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 GAO88519.1 - 0.017 15.4 3.0 0.017 15.4 2.1 6.5 3 2 3 6 6 6 0 Protein of unknown function (DUF972) Filament PF00038.16 GAO88519.1 - 0.13 11.6 65.5 5.5 6.3 9.4 4.6 2 1 1 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 GAO88519.1 - 2.1 7.4 24.2 0.066 12.3 1.5 4.2 3 1 1 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 GAO88519.1 - 4 6.9 72.9 0.24 10.9 1.7 6.1 3 2 2 5 5 5 0 IncA protein EF-hand_7 PF13499.1 GAO88520.1 - 9.8e-26 89.6 9.9 1.5e-12 47.4 0.7 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAO88520.1 - 4.2e-23 78.8 10.5 2.5e-07 29.4 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 GAO88520.1 - 1e-21 74.8 3.1 3.1e-05 23.4 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 GAO88520.1 - 5.1e-16 57.2 8.8 0.00043 19.4 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 GAO88520.1 - 2.3e-12 46.3 13.2 2.4e-05 23.8 0.8 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 GAO88520.1 - 3.7e-07 29.8 5.4 0.017 14.8 0.1 3.6 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAO88520.1 - 0.0051 16.6 1.0 0.41 10.5 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain EF-hand_10 PF14788.1 GAO88520.1 - 0.019 14.5 0.7 1.8 8.3 0.0 3.3 3 0 0 3 3 3 0 EF hand Zn_clus PF00172.13 GAO88520.1 - 0.043 13.7 1.4 0.083 12.8 1.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1679 PF07914.6 GAO88520.1 - 0.1 11.1 0.2 6.8 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EMP70 PF02990.11 GAO88521.1 - 5.7e-190 632.2 0.4 7.4e-190 631.8 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 GAO88521.1 - 0.064 13.3 0.0 0.064 13.3 0.0 4.3 4 1 0 4 4 4 0 NfeD-like C-terminal, partner-binding Sas10_Utp3 PF04000.10 GAO88522.1 - 2e-17 63.1 0.7 3.7e-17 62.2 0.5 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Myc_N PF01056.13 GAO88522.1 - 0.49 9.5 12.4 0.18 10.9 4.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF913 PF06025.7 GAO88522.1 - 0.68 8.6 4.5 0.32 9.6 0.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FMO-like PF00743.14 GAO88523.1 - 6.9e-23 80.6 0.0 2.6e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAO88523.1 - 3.7e-21 76.1 0.0 7.9e-21 75.0 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO88523.1 - 4.7e-10 38.9 0.0 1.4e-07 30.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAO88523.1 - 1.8e-09 37.7 0.0 3.9e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO88523.1 - 1.4e-06 28.2 0.7 4.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO88523.1 - 3.8e-06 27.2 1.4 0.067 13.6 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88523.1 - 5.9e-06 26.1 0.1 0.054 13.2 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 GAO88523.1 - 7.1e-05 21.8 0.3 0.00014 20.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAO88523.1 - 0.00036 20.6 0.2 0.16 12.0 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAO88523.1 - 0.00043 19.9 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO88523.1 - 0.0025 17.3 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 GAO88523.1 - 0.0038 17.4 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 GAO88523.1 - 0.05 12.4 0.1 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAO88523.1 - 0.073 11.5 1.6 0.37 9.1 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 GAO88523.1 - 0.12 11.4 0.0 14 4.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 GAO88523.1 - 0.91 8.2 4.6 0.095 11.5 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_4 PF01565.18 GAO88525.1 - 9.4e-15 54.2 0.1 1.5e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 5_nucleotid_C PF02872.13 GAO88526.1 - 2.5e-33 115.2 0.0 5.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAO88526.1 - 7e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 GAO88527.1 - 1.5e-06 28.3 0.0 9.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) EutB PF06751.6 GAO88527.1 - 0.15 10.3 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Hydantoinase_B PF02538.9 GAO88528.1 - 3.8e-189 629.3 0.0 4.9e-189 628.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAO88528.1 - 9.8e-95 316.9 0.6 2.4e-92 309.1 0.0 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAO88528.1 - 5.7e-54 182.2 0.0 8e-52 175.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region FAD_binding_4 PF01565.18 GAO88529.1 - 1.4e-26 92.6 0.6 2.2e-26 91.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO88529.1 - 1.3e-09 37.8 0.0 2.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3309 PF11752.3 GAO88529.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Fungal_trans PF04082.13 GAO88530.1 - 1.9e-19 69.5 0.1 5.2e-19 68.1 0.1 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 GAO88531.1 - 1.2e-16 60.3 0.4 1.7e-15 56.5 0.0 2.6 3 0 0 3 3 3 1 Cytochrome P450 TisB_toxin PF13939.1 GAO88531.1 - 0.89 9.3 4.2 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Cupin_2 PF07883.6 GAO88532.1 - 7e-14 51.0 0.7 7e-14 51.0 0.5 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 GAO88532.1 - 5.3e-06 25.9 0.1 7.1e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 GAO88532.1 - 1.5e-05 24.6 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 GAO88532.1 - 0.00028 20.2 0.1 0.00063 19.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 GAO88532.1 - 0.001 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 GAO88532.1 - 0.0019 17.7 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase GPI PF06560.6 GAO88532.1 - 0.0069 15.4 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 GAO88532.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase ARD PF03079.9 GAO88532.1 - 0.027 14.4 0.1 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family EF-hand_1 PF00036.27 GAO88534.1 - 0.39 10.1 2.6 0.88 9.0 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 GAO88534.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain Beta_helix PF13229.1 GAO88534.1 - 0.81 9.4 21.5 1.3 8.7 14.5 1.7 1 1 0 1 1 1 0 Right handed beta helix region EF-hand_5 PF13202.1 GAO88534.1 - 0.99 8.8 4.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 EF hand Amidase PF01425.16 GAO88535.1 - 1.6e-68 231.6 0.1 2.1e-65 221.3 0.0 2.1 2 0 0 2 2 2 2 Amidase Reprolysin_4 PF13583.1 GAO88536.1 - 1.9e-62 210.4 1.7 3.6e-62 209.5 1.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAO88536.1 - 4.8e-61 206.1 9.4 4.8e-61 206.1 6.5 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAO88536.1 - 1.5e-45 155.3 3.8 1.5e-45 155.3 2.6 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAO88536.1 - 5.9e-25 88.1 0.2 1.4e-24 86.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 GAO88536.1 - 1.3e-18 66.9 27.1 1.3e-18 66.9 18.8 3.4 3 0 0 3 3 3 1 Disintegrin Reprolysin PF01421.14 GAO88536.1 - 1.6e-05 24.5 14.1 4.8e-05 23.0 7.4 3.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 GAO88536.1 - 0.0003 20.6 0.1 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Sugar_tr PF00083.19 GAO88537.1 - 6.6e-104 347.9 23.7 9.8e-104 347.4 16.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88537.1 - 1e-28 100.0 31.4 5.5e-20 71.3 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.3 GAO88537.1 - 8.1 5.9 12.8 0.11 11.8 1.0 3.2 3 0 0 3 3 3 0 Intrinsic membrane protein PufX HAD_2 PF13419.1 GAO88539.1 - 2.8e-34 118.8 0.0 4.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.1 GAO88539.1 - 0.016 15.0 0.9 0.037 13.8 0.0 2.1 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Hydrolase PF00702.21 GAO88539.1 - 0.024 15.0 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAO88539.1 - 0.041 14.0 0.0 0.062 13.4 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AraC_N PF06719.8 GAO88539.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus DUF4047 PF13256.1 GAO88539.1 - 0.084 12.8 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) TauD PF02668.11 GAO88540.1 - 1.8e-44 152.3 0.1 2.4e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4237 PF14021.1 GAO88541.1 - 1.6e-31 108.3 0.0 2.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) Mannosyl_trans3 PF11051.3 GAO88542.1 - 6.1e-67 225.8 0.0 4.1e-66 223.1 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative HET PF06985.6 GAO88543.1 - 6.8e-24 84.6 0.0 1.2e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 GAO88544.1 - 9.1e-75 251.4 0.0 1.5e-74 250.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO88544.1 - 7.1e-62 208.8 0.0 1.1e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO88544.1 - 1.8e-23 82.2 0.0 4.3e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAO88544.1 - 1.6e-17 63.5 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.19 GAO88545.1 - 1.7e-74 251.0 24.2 2e-74 250.8 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88545.1 - 1.1e-24 86.8 26.7 1.9e-24 86.0 11.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO88545.1 - 2.8e-05 22.7 6.0 2.8e-05 22.7 4.2 3.0 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 GAO88545.1 - 0.0022 16.2 1.5 0.0035 15.5 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LIP PF03583.9 GAO88546.1 - 1.9e-14 53.5 0.0 2.1e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase FAD_binding_3 PF01494.14 GAO88547.1 - 5.8e-15 55.1 0.0 9.5e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAO88547.1 - 3e-05 22.8 0.3 0.0029 16.3 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 GAO88547.1 - 0.00013 21.9 0.2 0.00032 20.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO88547.1 - 0.00017 20.6 0.1 0.00026 20.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO88547.1 - 0.00046 19.9 0.1 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO88547.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO88547.1 - 0.014 14.3 2.1 0.026 13.4 1.5 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 GAO88547.1 - 0.16 10.8 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A BBS2_C PF14782.1 GAO88550.1 - 0.91 8.0 3.5 1.2 7.6 2.4 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Metallophos PF00149.23 GAO88552.1 - 1e-09 38.1 0.0 2.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO88552.1 - 1e-07 31.9 0.0 1.5e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyoxalase_2 PF12681.2 GAO88553.1 - 1.2e-13 51.6 0.0 1.4e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAO88553.1 - 2.2e-09 37.3 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_43 PF04616.9 GAO88554.1 - 6.3e-74 248.6 0.4 1e-73 247.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 GAO88555.1 - 1.3e-69 234.8 20.8 1.6e-69 234.6 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88555.1 - 5.9e-24 84.4 30.6 2.7e-16 59.2 8.4 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 GAO88555.1 - 0.00091 17.5 3.4 0.0016 16.6 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VHP PF02209.14 GAO88555.1 - 0.047 13.4 0.6 0.095 12.4 0.4 1.5 1 0 0 1 1 1 0 Villin headpiece domain PD40 PF07676.7 GAO88556.1 - 0.11 12.1 3.5 1.4 8.7 0.1 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Fungal_trans_2 PF11951.3 GAO88557.1 - 1.6e-05 23.6 3.2 0.00022 19.9 1.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO88558.1 - 2.8e-66 223.9 23.8 3.3e-66 223.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88558.1 - 1.8e-12 46.6 35.1 3.5e-08 32.5 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.13 GAO88559.1 - 1.9e-139 464.8 0.0 5.1e-138 460.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Bac_rhamnosid PF05592.6 GAO88560.1 - 9.8e-169 561.7 0.0 5.4e-167 556.0 0.0 2.0 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAO88560.1 - 4e-55 185.9 0.0 8e-55 184.9 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain GDE_C PF06202.9 GAO88560.1 - 0.034 12.8 0.2 0.086 11.5 0.0 1.6 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase PI-PLC-X PF00388.14 GAO88561.1 - 4.7e-07 29.3 0.0 7.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH3_9 PF14604.1 GAO88562.1 - 5.7e-09 35.4 0.1 1.2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO88562.1 - 1.7e-06 27.2 0.1 3.8e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAO88562.1 - 1.1e-05 24.7 0.1 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-HC5HC2H_2 PF13832.1 GAO88562.1 - 0.038 13.9 5.5 0.068 13.1 3.8 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Gemini_AL1_M PF08283.6 GAO88562.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain FYVE_2 PF02318.11 GAO88562.1 - 0.29 11.0 7.5 0.087 12.7 3.0 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.1 GAO88562.1 - 1.2 9.0 8.3 3.1 7.7 5.7 1.8 1 1 0 1 1 1 0 Ring finger domain 4HBT_3 PF13622.1 GAO88563.1 - 4.9e-36 124.7 0.0 9.5e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-CoA_dh_1 PF00441.19 GAO88563.1 - 5e-30 104.5 2.9 8.9e-30 103.7 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lactamase_B PF00753.22 GAO88563.1 - 3.6e-18 65.9 0.4 3.6e-18 65.9 0.3 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Acyl-CoA_dh_M PF02770.14 GAO88563.1 - 5.7e-18 64.1 0.0 1.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO88563.1 - 3.5e-14 53.1 4.5 9.1e-14 51.8 3.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO88563.1 - 1.9e-11 44.5 1.2 5.9e-11 42.9 0.1 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain NAD_binding_2 PF03446.10 GAO88563.1 - 1.5e-08 34.6 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAO88563.1 - 4.7e-07 29.9 0.1 1.2e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Lactamase_B_2 PF12706.2 GAO88563.1 - 0.00015 21.3 0.3 0.0003 20.3 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 GAO88564.1 - 1e-23 84.0 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88564.1 - 6.1e-09 35.7 0.0 9.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO88564.1 - 6.7e-09 35.8 0.0 8.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO88564.1 - 4.8e-05 23.4 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO88564.1 - 0.00039 19.9 0.0 0.0045 16.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAO88564.1 - 0.00065 18.7 0.1 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO88564.1 - 0.0018 18.3 0.1 0.0041 17.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 GAO88564.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 GAO88564.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAO88564.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HHH_5 PF14520.1 GAO88564.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Polysacc_synt_2 PF02719.10 GAO88564.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 GAO88564.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 GAO88564.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 GAO88564.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 GAO88565.1 - 5.7e-09 35.7 8.5 1.1e-08 34.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3659 PF12396.3 GAO88568.1 - 6.2e-122 397.3 58.1 7.6e-22 76.7 1.9 7.0 7 0 0 7 7 7 6 Protein of unknown function (DUF3659) TraC_F_IV PF11130.3 GAO88568.1 - 0.083 12.3 0.6 11 5.3 0.1 2.2 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Clavanin PF05452.6 GAO88568.1 - 0.16 12.0 4.9 0.43 10.5 0.4 3.8 3 1 0 3 3 3 0 Clavanin FUSC-like PF12805.2 GAO88568.1 - 8.7 5.1 4.9 6.5 5.5 0.3 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS TauD PF02668.11 GAO88569.1 - 7.8e-31 107.6 0.0 9.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF899 PF05988.7 GAO88570.1 - 6.5e-70 234.8 0.0 7.8e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) RNA_pol_Rpb5_C PF01191.14 GAO88570.1 - 0.034 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Glyoxalase_2 PF12681.2 GAO88571.1 - 3.4e-11 43.7 0.0 4.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyco_hydro_61 PF03443.9 GAO88572.1 - 4.1e-78 262.1 0.1 5.9e-78 261.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 GAO88572.1 - 0.0082 16.1 0.1 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Pyr_redox_3 PF13738.1 GAO88574.1 - 6.4e-28 98.2 0.0 3.1e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO88574.1 - 1.4e-11 44.2 0.0 5e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAO88574.1 - 4.8e-11 41.5 0.0 5.6e-10 38.0 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO88574.1 - 2.6e-10 39.7 0.0 1.1e-06 27.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAO88574.1 - 1.1e-07 31.2 0.0 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAO88574.1 - 1e-06 27.9 0.0 6.2e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO88574.1 - 2.7e-06 26.5 0.0 5.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAO88574.1 - 1.3e-05 25.4 0.1 0.12 12.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 GAO88574.1 - 6.4e-05 21.3 0.0 0.21 9.6 0.0 2.5 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 GAO88574.1 - 0.0003 20.7 0.3 0.21 11.4 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88574.1 - 0.0035 17.1 0.4 0.32 10.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 GAO88574.1 - 0.014 15.4 0.0 0.87 9.6 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 GAO88574.1 - 0.015 14.2 0.1 0.098 11.4 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain ApbA PF02558.11 GAO88574.1 - 0.021 14.2 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 GAO88575.1 - 5e-45 154.4 0.3 2.3e-44 152.2 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO88575.1 - 7.4e-13 48.3 0.5 7.4e-13 48.3 0.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO88575.1 - 6.5e-11 41.7 4.6 4.5e-10 38.9 3.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO88575.1 - 5e-08 32.4 0.1 7.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO88575.1 - 4.5e-07 28.6 0.9 7.3e-06 24.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAO88575.1 - 1.8e-06 28.2 0.4 0.00082 19.7 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO88575.1 - 6.2e-06 25.3 2.1 9.9e-06 24.6 1.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO88575.1 - 2.2e-05 24.4 0.2 2.2e-05 24.4 0.1 2.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO88575.1 - 4e-05 22.7 0.2 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAO88575.1 - 4.1e-05 23.7 0.4 0.0015 18.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO88575.1 - 7.1e-05 22.0 0.1 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAO88575.1 - 7.4e-05 21.9 0.2 0.00014 21.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 GAO88575.1 - 0.00017 20.5 0.2 0.00017 20.5 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 GAO88575.1 - 0.02 14.6 0.1 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 GAO88575.1 - 0.022 13.1 0.0 0.032 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 GAO88575.1 - 0.033 13.8 0.3 0.063 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prenylcys_lyase PF07156.9 GAO88575.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.3 1 1 0 1 1 1 0 Prenylcysteine lyase NAD_binding_10 PF13460.1 GAO88575.1 - 0.13 12.3 0.7 0.28 11.1 0.5 1.6 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_9 PF13454.1 GAO88575.1 - 0.16 11.6 0.6 0.84 9.3 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAO88575.1 - 0.17 11.2 0.3 0.46 9.8 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PhageMin_Tail PF10145.4 GAO88576.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein Saccharop_dh PF03435.13 GAO88577.1 - 3.4e-20 72.3 0.2 3.9e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 GAO88577.1 - 0.062 13.2 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding PCYCGC PF13798.1 GAO88577.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif CMAS PF02353.15 GAO88578.1 - 4.6e-59 199.7 0.1 5.6e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAO88578.1 - 2.4e-09 37.0 0.0 5.8e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO88578.1 - 1.9e-05 25.0 0.0 4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO88578.1 - 7.2e-05 22.8 0.0 0.00068 19.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO88578.1 - 0.0042 17.5 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88578.1 - 0.0047 17.4 0.0 0.039 14.5 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 GAO88578.1 - 0.0078 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAO88578.1 - 0.0081 16.4 0.0 0.047 14.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88578.1 - 0.011 15.3 0.0 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 GAO88578.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 GAO88578.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 ArabFuran-catal PF09206.6 GAO88579.1 - 1.6e-168 559.7 17.9 1.6e-168 559.7 12.4 1.4 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAO88579.1 - 3e-64 215.0 4.0 4.5e-64 214.4 2.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Pyr_redox_2 PF07992.9 GAO88580.1 - 5.9e-08 32.8 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88580.1 - 0.01 15.6 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Staphylcoagulse PF04022.7 GAO88580.1 - 4.1 6.8 8.1 7.7 5.9 0.1 3.4 3 0 0 3 3 3 0 Staphylocoagulase repeat ADH_zinc_N_2 PF13602.1 GAO88581.1 - 1.4e-15 58.2 0.0 3.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAO88581.1 - 3.9e-10 39.3 0.1 5.8e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO88581.1 - 0.0036 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAO88581.1 - 0.04 13.9 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding HD PF01966.17 GAO88582.1 - 5.7e-05 23.1 0.0 9.9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 HD domain HET PF06985.6 GAO88583.1 - 0.0023 18.0 0.9 0.0073 16.4 0.6 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PBP1_TM PF14812.1 GAO88583.1 - 3.1 8.1 11.9 0.39 11.0 0.1 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfotransfer_3 PF13469.1 GAO88586.1 - 7.3e-09 36.7 9.9 1.9e-08 35.3 6.9 1.7 1 1 0 1 1 1 1 Sulfotransferase family p450 PF00067.17 GAO88587.1 - 3.6e-63 213.6 0.0 4.5e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1456 PF07308.8 GAO88587.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Prenyltrans_1 PF13243.1 GAO88588.1 - 3.7e-13 49.4 0.1 0.00058 19.8 0.0 3.9 3 1 0 3 3 3 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAO88588.1 - 5.4e-09 36.4 1.0 0.26 11.7 0.0 3.6 3 0 0 3 3 3 3 Prenyltransferase-like Prenyltrans PF00432.16 GAO88588.1 - 0.00047 19.6 0.2 5.9 6.5 0.0 3.9 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat PBP-Tp47_a PF14889.1 GAO88588.1 - 0.086 12.1 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Acetyltransf_3 PF13302.1 GAO88589.1 - 9.7e-33 113.3 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAO88589.1 - 0.0012 18.7 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO88589.1 - 0.018 15.0 0.0 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family COesterase PF00135.23 GAO88590.1 - 8.4e-76 255.7 0.0 1.5e-75 254.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Zn_clus PF00172.13 GAO88590.1 - 4.2e-07 29.7 9.9 7.7e-07 28.9 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 GAO88590.1 - 9.1e-07 28.6 0.2 2.3e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 GAO88590.1 - 7.2e-06 24.8 0.1 1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 GAO88591.1 - 2.2e-09 36.8 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Imm7 PF15588.1 GAO88592.1 - 1.2e-21 76.8 0.0 1.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Immunity protein 7 FAD_binding_3 PF01494.14 GAO88593.1 - 5.5e-26 91.4 0.0 1e-24 87.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO88593.1 - 9.3e-07 28.7 0.1 2.6e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO88593.1 - 4.7e-06 25.7 0.0 0.0044 15.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO88593.1 - 0.0002 20.4 0.1 0.011 14.6 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO88593.1 - 0.00027 19.9 0.5 0.00098 18.0 0.1 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO88593.1 - 0.00028 20.8 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO88593.1 - 0.00036 19.7 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAO88593.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO88593.1 - 0.0015 17.0 0.0 0.0049 15.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 GAO88593.1 - 0.0019 17.9 0.3 0.062 13.0 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 GAO88593.1 - 0.0021 16.9 0.0 0.03 13.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_oxidored PF12831.2 GAO88593.1 - 0.038 13.0 0.1 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAO88593.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 GAO88593.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 GAO88593.1 - 0.11 11.0 0.0 3.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Zn_clus PF00172.13 GAO88593.1 - 0.12 12.3 5.7 0.2 11.6 3.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 GAO88593.1 - 0.13 12.7 0.1 20 5.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO88593.1 - 0.16 10.8 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_2 PF00891.13 GAO88594.1 - 1.4e-33 116.0 0.0 2.9e-33 115.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 GAO88594.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 GAO88594.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB p450 PF00067.17 GAO88595.1 - 2.8e-26 92.0 0.0 3.3e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAO88596.1 - 3.7e-31 108.1 0.0 4.9e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF123 PF01986.11 GAO88596.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 YfhD PF14151.1 GAO88596.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 YfhD-like protein Pyr_redox_2 PF07992.9 GAO88597.1 - 1.7e-19 70.5 0.0 2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO88597.1 - 1.3e-05 24.2 0.8 4.7e-05 22.4 0.1 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO88597.1 - 3.3e-05 22.5 0.0 0.005 15.3 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 GAO88597.1 - 7.5e-05 22.8 0.1 0.22 11.5 0.1 2.5 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88597.1 - 0.00011 22.0 1.4 0.088 12.5 0.1 2.4 1 1 1 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAO88597.1 - 0.00016 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAO88597.1 - 0.00021 20.2 0.1 0.00094 18.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAO88597.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO88597.1 - 0.0054 15.8 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAO88597.1 - 0.016 14.1 0.0 0.036 12.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 GAO88597.1 - 0.024 13.5 2.8 0.34 9.7 0.2 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A Cytochrom_C PF00034.16 GAO88597.1 - 0.038 14.8 0.0 0.085 13.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c Trp_halogenase PF04820.9 GAO88597.1 - 0.059 11.9 0.1 0.12 10.9 0.1 1.5 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 GAO88597.1 - 0.11 11.6 0.8 0.19 10.7 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAO88597.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 GAO88598.1 - 1.2e-48 165.8 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAO88598.1 - 5.2e-36 124.0 0.0 8.5e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Aminotran_1_2 PF00155.16 GAO88598.1 - 1.3e-32 113.1 0.0 2.7e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO88598.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Peripla_BP_2 PF01497.13 GAO88598.1 - 0.22 10.6 0.1 0.54 9.3 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein MFS_1 PF07690.11 GAO88599.1 - 4.1e-39 134.3 52.7 4.1e-38 131.0 35.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO88599.1 - 6.3e-17 61.2 7.9 6.3e-17 61.2 5.4 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO88599.1 - 5.4e-15 54.6 15.9 5.4e-15 54.6 11.0 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GST_C_2 PF13410.1 GAO88600.1 - 7.9e-07 28.8 0.7 1.5e-06 28.0 0.4 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO88600.1 - 1.3e-06 28.3 0.0 4.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO88600.1 - 2e-06 28.1 0.3 3.2e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO88600.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO88600.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO88600.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_M19 PF01244.16 GAO88601.1 - 3e-103 345.1 0.0 3.9e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.17 GAO88602.1 - 2.5e-58 197.7 0.0 3.2e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 GAO88603.1 - 5.2e-89 298.8 37.0 6.1e-89 298.5 25.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.16 GAO88604.1 - 1.6e-65 220.7 0.0 1.9e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_2 PF07992.9 GAO88605.1 - 4.5e-22 78.9 0.0 1.7e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO88605.1 - 1.3e-09 37.4 0.8 0.00013 21.0 0.0 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 GAO88605.1 - 2.2e-08 33.3 2.1 0.00083 18.3 0.0 2.5 1 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAO88605.1 - 1.4e-07 30.7 1.2 9.9e-05 21.3 0.1 2.9 2 1 1 3 3 3 2 FAD binding domain HI0933_like PF03486.9 GAO88605.1 - 1e-06 27.5 0.1 0.007 14.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 GAO88605.1 - 1.5e-06 28.0 1.4 0.00058 19.6 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAO88605.1 - 1.9e-06 28.0 0.4 0.027 14.5 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO88605.1 - 0.0029 16.5 0.2 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAO88605.1 - 0.0038 16.3 0.5 0.007 15.4 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO88605.1 - 0.0041 17.1 0.6 0.0097 15.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAO88605.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAO88605.1 - 0.017 14.0 0.1 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 GAO88605.1 - 0.019 14.0 0.4 0.099 11.6 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO88605.1 - 0.021 15.2 0.4 0.17 12.2 0.3 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO88605.1 - 0.021 13.9 0.5 3.1 6.7 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 GAO88605.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 GAO88605.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding MBOAT_2 PF13813.1 GAO88606.1 - 1.8e-18 66.4 5.3 1.8e-18 66.4 3.7 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.17 GAO88607.1 - 5.1e-48 163.7 0.0 7.5e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAO88608.1 - 3.9e-34 117.9 0.0 5.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO88608.1 - 6.1e-05 23.5 0.2 0.00041 20.9 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain TrmB PF01978.14 GAO88608.1 - 0.0051 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MTS PF05175.9 GAO88608.1 - 0.017 14.4 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAO88608.1 - 0.032 13.8 0.1 0.24 10.9 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.1 GAO88608.1 - 0.048 13.6 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_12 PF08242.7 GAO88608.1 - 0.079 13.4 0.0 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 GAO88609.1 - 1.3e-26 93.1 0.0 1.5e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1857 PF08982.6 GAO88610.1 - 2.5e-19 69.3 0.0 2.7e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) AMP-binding PF00501.23 GAO88611.1 - 7.5e-86 288.1 0.0 1.2e-85 287.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAO88611.1 - 2.2e-49 167.9 0.1 7e-28 97.3 0.1 3.1 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO88611.1 - 2.6e-25 88.4 0.2 1.1e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO88611.1 - 3e-09 37.0 0.0 5.7e-06 26.5 0.0 3.1 2 0 0 2 2 2 2 HxxPF-repeated domain ABC_tran PF00005.22 GAO88613.1 - 5.2e-35 120.7 0.0 8.5e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAO88613.1 - 1.4e-16 60.7 8.4 2.2e-16 60.0 5.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 GAO88613.1 - 1.6e-06 28.2 0.0 4.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 GAO88613.1 - 1.7e-06 28.2 0.0 0.0021 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAO88613.1 - 3.1e-06 26.5 0.0 0.001 18.3 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAO88613.1 - 0.00036 20.6 0.0 0.0017 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 GAO88613.1 - 0.00047 20.0 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_29 PF13555.1 GAO88613.1 - 0.00081 18.8 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAO88613.1 - 0.0028 17.5 0.3 0.029 14.2 0.2 2.6 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAO88613.1 - 0.0045 16.4 0.1 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_15 PF13175.1 GAO88613.1 - 0.008 15.2 0.0 0.061 12.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 GAO88613.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAO88613.1 - 0.025 14.2 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 GAO88613.1 - 0.031 15.0 0.0 0.082 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAO88613.1 - 0.035 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAO88613.1 - 0.036 14.3 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAO88613.1 - 0.04 13.3 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAO88613.1 - 0.048 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 GAO88613.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAO88613.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 GAO88613.1 - 0.085 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 GAO88613.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 GAO88614.1 - 2.9e-59 200.1 0.0 4e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAO88614.1 - 3.8e-24 85.3 0.5 6.4e-24 84.6 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAO88614.1 - 3.8e-22 78.2 0.3 7.8e-22 77.2 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 GAO88614.1 - 0.0027 16.8 0.1 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 GAO88614.1 - 0.014 14.8 0.3 0.049 13.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 GAO88614.1 - 0.016 14.8 0.4 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAO88614.1 - 0.022 13.9 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 GAO88614.1 - 0.023 14.8 0.0 0.39 10.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO88614.1 - 0.039 13.9 0.1 0.19 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 GAO88614.1 - 0.054 13.2 0.5 5.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 GAO88614.1 - 0.056 13.0 1.2 0.084 12.5 0.0 1.8 2 0 0 2 2 1 0 NACHT domain RNA_helicase PF00910.17 GAO88614.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 GAO88614.1 - 0.081 13.0 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAO88614.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 GAO88614.1 - 0.51 9.1 1.6 0.59 8.9 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AIG2_2 PF13772.1 GAO88615.1 - 0.00054 20.0 0.1 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family Zn_clus PF00172.13 GAO88616.1 - 2.8e-08 33.5 6.0 6.4e-08 32.3 4.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.4 GAO88617.1 - 1.5e-17 63.5 0.2 2.1e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAO88617.1 - 3.4e-09 36.2 1.4 1.5e-08 34.1 1.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO88617.1 - 9.7e-08 31.8 0.5 1.3e-07 31.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO88617.1 - 2.9e-05 24.0 0.2 3.6e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tannase PF07519.6 GAO88617.1 - 0.00012 20.9 1.1 0.00014 20.7 0.8 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.15 GAO88617.1 - 0.00031 20.2 0.5 0.00041 19.8 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAO88617.1 - 0.00064 19.3 0.1 0.00095 18.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAO88617.1 - 0.001 18.3 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAO88617.1 - 0.0025 17.5 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 GAO88617.1 - 0.0049 16.4 0.1 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 GAO88617.1 - 0.074 11.5 0.2 0.22 9.9 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2235 PF09994.4 GAO88617.1 - 0.085 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3180 PF11377.3 GAO88618.1 - 0.12 12.2 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Cellulase PF00150.13 GAO88619.1 - 2.2e-18 66.4 2.0 3.3e-16 59.3 1.4 2.3 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Bac_rhamnosid PF05592.6 GAO88620.1 - 4.5e-34 117.5 0.0 1e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAO88620.1 - 1e-07 31.0 0.1 2.9e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF608 Bac_rhamnosid_N PF08531.5 GAO88620.1 - 0.00043 19.8 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Zn_clus PF00172.13 GAO88621.1 - 1.1e-08 34.8 8.2 1.6e-08 34.2 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO88621.1 - 1.5e-07 30.5 1.3 2.1e-07 30.0 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO88622.1 - 9.7e-52 176.0 21.1 3e-51 174.4 14.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88622.1 - 5.9e-12 44.9 28.2 7.7e-11 41.2 19.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2839 PF10999.3 GAO88622.1 - 0.021 14.8 0.0 0.071 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF4377 PF14302.1 GAO88622.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) MFS_2 PF13347.1 GAO88622.1 - 0.15 10.3 30.1 0.026 12.9 3.0 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein Glyco_hydro_28 PF00295.12 GAO88623.1 - 2e-48 165.0 4.8 3.1e-48 164.4 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Lipase_GDSL_2 PF13472.1 GAO88625.1 - 6.2e-10 39.4 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family IncA PF04156.9 GAO88625.1 - 0.33 10.5 1.9 0.49 9.9 1.3 1.1 1 0 0 1 1 1 0 IncA protein ALAD PF00490.16 GAO88626.1 - 6.9e-112 373.5 0.0 8.9e-112 373.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac PF12464.3 GAO88627.1 - 9.3e-14 51.1 0.0 2.5e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAO88627.1 - 1.2e-10 40.4 6.0 0.00011 21.4 0.1 4.5 5 0 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAO88627.1 - 8.4e-10 38.0 2.5 2.9e-06 26.7 0.0 3.7 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 GAO88627.1 - 1.6e-09 37.4 8.2 3.1e-09 36.5 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRM1_C PF08767.6 GAO88628.1 - 6.7e-137 455.6 10.8 6.7e-137 455.6 7.5 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 GAO88628.1 - 1.7e-41 141.5 6.6 1.7e-41 141.5 4.6 3.5 3 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAO88628.1 - 4.7e-11 42.4 0.2 2.2e-10 40.3 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain uDENN PF03456.13 GAO88628.1 - 0.18 11.7 0.9 1.1 9.2 0.1 2.6 3 0 0 3 3 3 0 uDENN domain HD_assoc PF13286.1 GAO88628.1 - 0.47 10.7 3.6 8.2 6.7 0.1 4.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Shugoshin_N PF07558.6 GAO88629.1 - 3.5e-16 58.6 4.1 8.4e-16 57.4 2.9 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 GAO88629.1 - 5.3e-11 41.7 6.0 2.3e-10 39.7 4.2 2.2 1 0 0 1 1 1 1 Shugoshin C terminus Snapin_Pallidin PF14712.1 GAO88629.1 - 0.032 14.5 0.4 0.073 13.3 0.3 1.6 1 0 0 1 1 1 0 Snapin/Pallidin p450 PF00067.17 GAO88630.1 - 1.3e-70 238.2 0.0 1.5e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 GAO88631.1 - 5.3e-50 170.3 0.0 7.8e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO88631.1 - 3.8e-09 35.8 1.2 1e-08 34.4 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAO88631.1 - 5.6e-07 28.9 0.0 2.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO88631.1 - 0.00036 20.4 0.1 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAO88631.1 - 0.0036 16.9 0.2 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 GAO88631.1 - 0.005 16.8 0.2 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO88631.1 - 0.012 16.0 0.2 0.041 14.2 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO88631.1 - 0.021 13.6 0.2 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAO88631.1 - 0.031 12.7 0.4 0.046 12.1 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAO88631.1 - 0.073 11.9 0.0 0.17 10.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 GAO88631.1 - 0.097 11.7 0.3 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_10 PF13460.1 GAO88631.1 - 0.11 12.5 0.2 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 NADH(P)-binding GDI PF00996.13 GAO88631.1 - 0.13 10.5 0.0 0.22 9.8 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF814 PF05670.8 GAO88632.1 - 1.2e-10 41.1 0.0 2.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) FRG1 PF06229.7 GAO88632.1 - 0.0025 17.2 4.1 0.0034 16.8 2.9 1.1 1 0 0 1 1 1 1 FRG1-like family BSMAP PF12280.3 GAO88632.1 - 0.2 11.5 2.9 0.22 11.3 2.0 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Pinin_SDK_memA PF04696.8 GAO88632.1 - 6 6.4 20.8 12 5.5 14.3 1.6 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region GRAB PF10375.4 GAO88633.1 - 2.5e-08 33.2 0.2 5.9e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 GAO88633.1 - 8.2e-07 28.5 12.8 0.00017 20.9 3.9 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 GAO88633.1 - 8.4e-05 20.5 51.5 0.00014 19.7 35.7 1.3 1 0 0 1 1 1 1 Myosin tail Baculo_PEP_C PF04513.7 GAO88633.1 - 0.0067 16.2 19.7 0.042 13.6 5.7 2.8 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 GAO88633.1 - 0.041 13.0 53.6 0.013 14.6 5.4 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 GAO88633.1 - 0.22 8.7 46.5 0.37 8.0 32.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) COG5 PF10392.4 GAO88633.1 - 0.46 10.4 22.1 0.59 10.0 7.8 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Filament PF00038.16 GAO88633.1 - 0.7 9.2 51.6 0.84 9.0 11.6 3.1 1 1 2 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 GAO88633.1 - 0.76 9.5 59.7 0.21 11.3 11.8 4.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 GAO88633.1 - 1.1 7.6 42.3 2.5 6.4 15.4 2.2 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 GAO88633.1 - 1.9 8.3 60.2 2.2 8.1 13.0 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 GAO88633.1 - 1.9 7.3 39.4 0.1 11.5 12.7 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) ApoO PF09769.4 GAO88633.1 - 2.2 7.9 8.9 19 4.9 0.7 3.3 1 1 2 3 3 3 0 Apolipoprotein O Tropomyosin PF00261.15 GAO88633.1 - 3.1 6.7 54.5 1.8 7.6 6.0 3.5 1 1 1 3 3 3 0 Tropomyosin HOOK PF05622.7 GAO88633.1 - 4.8 4.8 53.3 1.2 6.8 15.2 2.7 1 1 2 3 3 3 0 HOOK protein Guanylate_kin PF00625.16 GAO88634.1 - 1.3e-64 217.0 0.0 1.6e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 GAO88634.1 - 1.8e-07 31.1 0.1 2.1e-06 27.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO88634.1 - 4.7e-06 26.7 0.1 9e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAO88634.1 - 5.7e-06 27.1 0.1 4.7e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 GAO88634.1 - 1.8e-05 24.9 0.0 7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAO88634.1 - 2.7e-05 24.4 0.3 0.00021 21.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 GAO88634.1 - 0.00023 20.4 0.0 0.00072 18.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 GAO88634.1 - 0.00056 19.6 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 GAO88634.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 GAO88634.1 - 0.0013 18.6 0.1 0.0035 17.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAO88634.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 GAO88634.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 GAO88634.1 - 0.0039 17.6 0.0 0.0067 16.9 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein NACHT PF05729.7 GAO88634.1 - 0.0052 16.4 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 GAO88634.1 - 0.006 16.7 0.0 0.022 14.9 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 GAO88634.1 - 0.0065 16.4 0.0 0.0097 15.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAO88634.1 - 0.0076 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 GAO88634.1 - 0.0084 15.0 0.0 0.02 13.8 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 GAO88634.1 - 0.0098 14.8 0.0 0.039 12.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 GAO88634.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 GAO88634.1 - 0.012 15.3 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 GAO88634.1 - 0.012 15.1 0.7 0.054 13.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAO88634.1 - 0.012 15.0 0.1 0.037 13.4 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 GAO88634.1 - 0.024 14.9 0.2 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAO88634.1 - 0.035 13.6 0.1 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAO88634.1 - 0.052 12.9 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAO88634.1 - 0.056 13.1 0.0 0.094 12.4 0.0 1.5 1 1 0 1 1 1 0 NTPase DUF1895 PF08988.5 GAO88634.1 - 0.065 13.2 0.3 0.13 12.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1895) MobB PF03205.9 GAO88634.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAO88634.1 - 0.11 11.8 0.1 0.57 9.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 GAO88634.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 GAO88635.1 - 1.5e-113 378.5 0.6 1.8e-113 378.2 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAO88635.1 - 4.5e-07 29.8 0.0 8.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAO88635.1 - 8.2e-06 25.0 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 GAO88635.1 - 5.1e-05 22.5 0.0 9.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAO88635.1 - 0.00018 21.0 0.4 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAO88635.1 - 0.00022 21.1 0.5 0.55 10.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 GAO88635.1 - 0.0024 17.3 0.2 0.0024 17.3 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 GAO88635.1 - 0.0049 17.2 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAO88635.1 - 0.0073 16.6 0.5 0.015 15.5 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 GAO88635.1 - 0.015 14.4 0.1 0.08 12.0 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAO88635.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAO88635.1 - 0.021 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 GAO88635.1 - 0.024 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 GAO88635.1 - 0.039 14.4 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 GAO88635.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 GAO88635.1 - 0.076 11.9 0.1 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAO88635.1 - 0.13 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 GAO88636.1 - 1.6e-12 46.7 5.5 0.0012 18.6 0.1 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAO88636.1 - 0.017 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like PQQ_3 PF13570.1 GAO88636.1 - 0.032 14.5 2.8 3 8.2 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.6 GAO88636.1 - 0.075 12.2 0.0 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 GAO88636.1 - 0.13 10.5 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Spindle_Spc25 PF08234.7 GAO88637.1 - 6.4e-21 74.1 0.2 2.4e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4140 PF13600.1 GAO88637.1 - 0.36 11.3 5.7 0.86 10.0 3.9 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AHS1 PF02682.11 GAO88637.1 - 0.45 9.9 1.8 0.79 9.1 1.2 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Filament PF00038.16 GAO88637.1 - 0.46 9.9 16.0 1.3 8.4 11.1 1.7 1 1 0 1 1 1 0 Intermediate filament protein Lsr2 PF11774.3 GAO88637.1 - 1.1 9.2 6.2 8.9 6.2 4.3 2.1 1 1 0 1 1 1 0 Lsr2 DUF3053 PF11254.3 GAO88637.1 - 1.6 7.9 9.8 3.9 6.6 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Atg14 PF10186.4 GAO88637.1 - 4.8 6.0 11.3 8.5 5.2 7.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 GAO88637.1 - 6.6 6.3 12.7 8.2 6.0 1.7 2.0 1 1 1 2 2 2 0 Mnd1 family Rrn6 PF10214.4 GAO88638.1 - 1.7e-207 691.1 0.1 2.2e-207 690.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor HMA PF00403.21 GAO88638.1 - 6.5e-07 29.3 1.0 1.3e-06 28.4 0.7 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2293 PF10056.4 GAO88639.1 - 5.9e-29 99.8 0.1 1.6e-28 98.4 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) zinc_ribbon_6 PF14599.1 GAO88640.1 - 1.4e-25 88.8 0.4 1.4e-25 88.8 0.3 2.0 2 0 0 2 2 2 1 Zinc-ribbon Stc1 PF12898.2 GAO88640.1 - 5 7.2 9.6 17 5.5 0.2 2.5 1 1 1 2 2 2 0 Stc1 domain Tcp11 PF05794.8 GAO88641.1 - 5.1e-55 186.9 0.1 2.9e-54 184.4 0.0 2.0 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.22 GAO88641.1 - 0.046 13.3 0.8 0.17 11.6 0.6 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif WD40 PF00400.27 GAO88642.1 - 2.5e-54 179.3 19.9 9.9e-11 41.0 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAO88642.1 - 0.00015 21.1 0.0 0.13 11.8 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S10 PF00450.17 GAO88643.1 - 4.2e-115 385.2 0.2 5.1e-115 384.9 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Act-Frag_cataly PF09192.5 GAO88643.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF2207 PF09972.4 GAO88643.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_Me_trans PF04252.8 GAO88644.1 - 7.1e-47 159.3 0.0 8.1e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 GAO88645.1 - 2e-22 78.9 0.1 3.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.5 GAO88646.1 - 3.5e-146 487.0 17.6 4.1e-146 486.8 12.2 1.0 1 0 0 1 1 1 1 ICE2 UPF0160 PF03690.8 GAO88647.1 - 1.2e-117 392.8 0.0 1.4e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SGL PF08450.7 GAO88648.1 - 3.9e-19 68.9 0.1 3.6e-18 65.8 0.1 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 GAO88648.1 - 0.051 13.6 0.0 0.31 11.1 0.0 2.3 2 1 0 2 2 2 0 Strictosidine synthase Yae1_N PF09811.4 GAO88649.1 - 3e-07 29.8 6.0 5.4e-07 29.0 4.1 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.6 GAO88650.1 - 1.5e-143 478.1 0.0 2e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAO88650.1 - 1.1e-10 40.2 0.1 2.2e-06 26.0 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAO88650.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Elongin_A PF06881.6 GAO88650.1 - 0.24 11.7 3.3 0.72 10.2 2.3 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 GAO88650.1 - 0.68 9.8 5.1 2 8.2 3.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 GAO88651.1 - 2.5e-29 100.0 2.5 1.1e-07 31.4 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2686 PF10887.3 GAO88652.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) PXA PF02194.10 GAO88653.1 - 2.3e-55 187.0 0.3 2.3e-55 187.0 0.2 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 GAO88653.1 - 2.5e-28 98.4 2.0 2.6e-28 98.3 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 GAO88653.1 - 3.1e-21 75.2 0.5 7e-21 74.1 0.3 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.14 GAO88653.1 - 3.9e-12 46.3 0.1 9.8e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PEMT PF04191.8 GAO88654.1 - 1.4e-31 108.6 3.0 1.4e-31 108.6 2.1 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.1 GAO88654.1 - 0.071 12.7 0.9 0.071 12.7 0.7 2.5 3 0 0 3 3 3 0 YrhK-like protein DUF1673 PF07895.6 GAO88654.1 - 0.16 11.4 0.6 0.25 10.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) SpoVA PF03862.8 GAO88654.1 - 0.27 11.3 2.8 0.33 11.0 2.0 1.3 1 1 0 1 1 1 0 SpoVA protein RXT2_N PF08595.6 GAO88655.1 - 3.7e-43 146.8 0.1 3.7e-43 146.8 0.1 2.8 2 1 1 3 3 3 1 RXT2-like, N-terminal Gryzun PF07919.7 GAO88656.1 - 6.1e-144 480.3 0.0 8.3e-144 479.9 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 GAO88656.1 - 4.3e-103 344.0 0.8 2.3e-93 312.2 0.9 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 GAO88656.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 GAO88657.1 - 2.6e-19 70.0 2.1 4.2e-18 66.0 1.5 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO88657.1 - 1.9e-08 34.1 0.0 7.2e-07 29.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO88657.1 - 2.3e-06 27.3 0.0 5.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L6 PF00347.18 GAO88658.1 - 2.6e-16 59.8 1.9 3.1e-10 40.3 0.1 2.6 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.19 GAO88658.1 - 1.1e-15 57.3 0.0 8.1e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 GAO88658.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2375 PF09558.5 GAO88658.1 - 0.13 12.1 0.4 18 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2375) DUF3336 PF11815.3 GAO88659.1 - 6.5e-39 132.7 0.1 1.7e-38 131.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAO88659.1 - 4.5e-19 69.1 0.2 1e-18 68.0 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.9 GAO88659.1 - 0.077 12.6 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 NHR1 homology to TAF AA_permease_2 PF13520.1 GAO88660.1 - 1.4e-40 139.1 43.5 1.6e-40 138.9 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO88660.1 - 7e-29 100.4 38.6 9.2e-29 100.0 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease PhoD PF09423.5 GAO88661.1 - 6.1e-13 48.1 0.0 4.6e-09 35.3 0.2 2.2 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 GAO88663.1 - 1.6e-21 76.8 10.2 1.6e-21 76.8 7.1 1.6 2 0 0 2 2 2 1 Rhomboid family Syntaxin PF00804.20 GAO88664.1 - 0.00025 21.1 0.2 0.00037 20.6 0.1 1.3 1 0 0 1 1 1 1 Syntaxin Atg14 PF10186.4 GAO88664.1 - 0.031 13.2 0.1 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 GAO88664.1 - 0.037 13.8 0.3 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RP-C_C PF11800.3 GAO88664.1 - 0.072 12.7 0.7 0.1 12.2 0.5 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region FlaC_arch PF05377.6 GAO88664.1 - 0.13 12.1 0.7 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mob1_phocein PF03637.12 GAO88665.1 - 2.6e-31 108.6 2.0 1.8e-14 53.7 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 GAO88666.1 - 3.8e-33 114.6 0.0 6.5e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein BOP1NT PF08145.7 GAO88668.1 - 1.5e-107 359.1 5.9 2.2e-107 358.6 4.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 GAO88668.1 - 5.1e-30 102.2 5.3 2.4e-11 43.0 0.1 6.4 7 1 0 7 7 7 4 WD domain, G-beta repeat AAA PF00004.24 GAO88669.1 - 5.6e-89 295.1 0.0 5e-44 149.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO88669.1 - 3.5e-13 49.1 0.0 3.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAO88669.1 - 4.1e-13 49.7 0.8 2.2e-05 24.5 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 GAO88669.1 - 1.3e-12 48.0 0.3 0.0034 17.5 0.0 5.2 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.9 GAO88669.1 - 3.2e-11 43.1 0.1 0.00069 19.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAO88669.1 - 4.7e-11 43.5 0.0 1.6e-05 25.7 0.0 3.4 2 2 1 3 3 2 2 AAA domain AAA_2 PF07724.9 GAO88669.1 - 1.7e-10 41.0 0.0 0.00022 21.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAO88669.1 - 8.8e-10 38.6 0.0 0.00026 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAO88669.1 - 1.9e-09 37.5 0.0 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAO88669.1 - 3.4e-09 36.0 0.0 0.0013 17.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 GAO88669.1 - 1.3e-08 33.9 0.0 0.0001 21.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 GAO88669.1 - 2.7e-08 33.4 0.1 0.009 15.7 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 GAO88669.1 - 7.6e-08 32.4 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAO88669.1 - 1.4e-07 31.1 0.2 0.013 14.8 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 GAO88669.1 - 2.9e-07 30.6 0.0 0.02 15.0 0.0 2.9 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 GAO88669.1 - 3.1e-07 29.7 0.3 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAO88669.1 - 4.2e-07 29.6 0.0 0.0052 16.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAO88669.1 - 9.7e-07 28.3 4.3 0.4 10.0 0.0 4.4 2 2 2 4 4 4 2 AAA domain NACHT PF05729.7 GAO88669.1 - 1.3e-06 28.2 0.2 0.11 12.1 0.0 3.9 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.1 GAO88669.1 - 2.4e-06 27.8 0.0 0.032 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 GAO88669.1 - 2.4e-05 23.6 0.0 0.071 12.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 GAO88669.1 - 2.9e-05 24.1 0.0 0.41 10.6 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAO88669.1 - 3.6e-05 24.0 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter KaiC PF06745.8 GAO88669.1 - 3.7e-05 22.9 0.1 0.59 9.1 0.0 3.3 2 1 0 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 GAO88669.1 - 8.6e-05 22.5 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activat PF00158.21 GAO88669.1 - 9.5e-05 21.9 0.0 0.23 10.9 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain SKI PF01202.17 GAO88669.1 - 0.00014 21.7 0.0 0.45 10.3 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 GAO88669.1 - 0.0002 21.1 0.0 2 8.0 0.0 3.9 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 GAO88669.1 - 0.00047 19.1 0.0 0.26 10.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AFG1_ATPase PF03969.11 GAO88669.1 - 0.00084 18.2 0.0 0.17 10.6 0.0 2.5 3 0 0 3 3 2 1 AFG1-like ATPase Rad17 PF03215.10 GAO88669.1 - 0.0009 18.0 0.0 0.41 9.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 GAO88669.1 - 0.0011 17.9 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 GAO88669.1 - 0.0013 18.5 0.0 2.3 7.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 GAO88669.1 - 0.0021 17.6 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 GAO88669.1 - 0.0027 17.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 GAO88669.1 - 0.0029 16.5 0.0 0.057 12.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAO88669.1 - 0.0038 16.8 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 GAO88669.1 - 0.0092 15.6 0.0 2.1 8.0 0.0 3.0 2 1 0 3 3 3 1 NTPase ATP-synt_ab PF00006.20 GAO88669.1 - 0.012 15.0 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 GAO88669.1 - 0.013 15.0 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 GAO88669.1 - 0.048 12.8 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 GAO88669.1 - 0.049 12.5 0.0 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 GAO88669.1 - 0.051 13.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 GAO88669.1 - 0.08 13.2 0.2 3.2 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain MSA-2c PF12238.3 GAO88669.1 - 0.09 12.4 2.8 0.34 10.5 1.9 1.9 1 1 0 1 1 1 0 Merozoite surface antigen 2c AAA_30 PF13604.1 GAO88669.1 - 0.094 12.2 0.0 16 4.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain KTI12 PF08433.5 GAO88669.1 - 0.13 11.4 0.1 25 3.9 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Snf7 PF03357.16 GAO88670.1 - 2.2e-34 118.2 10.9 2.9e-34 117.9 7.6 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 GAO88670.1 - 0.019 14.9 0.2 0.085 12.8 0.1 2.1 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PMSR PF01625.16 GAO88670.1 - 0.12 12.2 1.0 5.7 6.7 0.1 2.4 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase HSCB_C PF07743.8 GAO88670.1 - 0.24 11.8 12.8 1 9.8 0.5 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Wbp11 PF09429.5 GAO88670.1 - 0.67 9.9 11.1 1.6 8.7 0.2 3.3 3 0 0 3 3 3 0 WW domain binding protein 11 DNA_topoisoIV PF00521.15 GAO88670.1 - 1.3 7.8 6.6 1.8 7.3 4.5 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2203 PF09969.4 GAO88670.1 - 3.4 7.8 6.3 4.2 7.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Nsp1_C PF05064.8 GAO88670.1 - 5.6 6.6 10.6 2.1 7.9 4.9 2.0 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF4559 PF15112.1 GAO88670.1 - 7.2 5.6 8.0 12 4.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) PITH PF06201.8 GAO88671.1 - 2.1e-46 157.4 0.0 2.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain HA2 PF04408.18 GAO88672.1 - 7.8e-22 77.2 0.1 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAO88672.1 - 2.3e-21 75.7 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAO88672.1 - 3.5e-12 46.0 0.0 7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO88672.1 - 1.4e-05 24.6 0.1 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO88672.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAO88672.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 GAO88672.1 - 0.011 15.1 0.0 0.066 12.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 GAO88672.1 - 0.012 14.5 0.2 0.046 12.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.1 GAO88672.1 - 0.02 14.8 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO88672.1 - 0.099 12.5 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAO88672.1 - 0.13 11.3 1.1 0.54 9.3 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin Herpes_ori_bp PF02399.10 GAO88672.1 - 0.15 9.9 0.0 0.22 9.4 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_23 PF13476.1 GAO88672.1 - 0.21 11.8 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 GAO88673.1 - 1e-12 47.8 0.3 2e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CUE PF02845.11 GAO88673.1 - 7.3e-10 38.1 0.0 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Acetyltransf_10 PF13673.1 GAO88673.1 - 3.9e-09 36.6 0.1 7.9e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO88673.1 - 1.2e-08 34.5 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAO88673.1 - 5.7e-07 29.6 0.2 1e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 GAO88673.1 - 1.3e-05 25.1 0.1 2.9e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO88673.1 - 0.00017 21.4 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 GAO88673.1 - 0.00053 19.9 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAO88673.1 - 0.0021 17.6 0.2 0.0041 16.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO88673.1 - 0.046 13.5 0.4 0.24 11.2 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 GAO88673.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase He_PIG PF05345.7 GAO88674.1 - 1.8e-20 72.6 21.7 1e-06 28.6 0.5 4.8 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.5 GAO88674.1 - 8.1e-06 25.0 1.0 8.1e-06 25.0 0.7 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 GAO88674.1 - 0.0012 18.3 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) RELT PF12606.3 GAO88674.1 - 0.0039 16.3 0.0 0.0099 14.9 0.0 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 EphA2_TM PF14575.1 GAO88674.1 - 0.026 14.9 0.8 0.054 13.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.1 GAO88674.1 - 0.42 10.7 3.6 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT PP2C PF00481.16 GAO88675.1 - 1.5e-81 273.5 0.0 2.4e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAO88675.1 - 0.00041 19.8 0.0 0.00089 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 GAO88676.1 - 1.9e-21 76.7 0.0 2.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase EamA PF00892.15 GAO88678.1 - 1.1e-17 64.2 28.4 1.2e-11 44.7 5.1 3.6 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 GAO88678.1 - 4.4e-06 26.8 5.4 4.4e-06 26.8 3.8 3.9 2 2 1 3 3 3 1 Multidrug resistance efflux transporter DUF606 PF04657.8 GAO88678.1 - 0.83 9.7 22.3 0.24 11.4 3.7 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF606 DUF1253 PF06862.7 GAO88679.1 - 1.2e-164 547.9 0.0 1.8e-164 547.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 GAO88679.1 - 0.0019 17.7 0.1 0.097 12.1 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase gp32 PF08804.5 GAO88679.1 - 0.062 13.4 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 gp32 DNA binding protein like JAB PF01398.16 GAO88680.1 - 2e-16 59.7 0.0 3.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAO88680.1 - 2.2e-16 59.9 0.0 4.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function GIY-YIG PF01541.19 GAO88681.1 - 0.024 14.9 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain TFIID-18kDa PF02269.11 GAO88682.1 - 1.4e-23 82.4 0.0 2.8e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 GAO88682.1 - 0.0022 18.0 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAO88682.1 - 0.0082 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 GAO88682.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S Bromo_TP PF07524.8 GAO88682.1 - 0.051 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 GAO88682.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 GAO88682.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SASP_gamma PF04259.9 GAO88682.1 - 0.41 10.8 4.5 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type PPR_2 PF13041.1 GAO88683.1 - 1.7e-14 53.5 1.6 1e-06 28.5 0.0 3.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 GAO88683.1 - 5.3e-08 32.5 4.9 0.24 11.7 0.0 7.5 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.15 GAO88683.1 - 1.7e-06 27.6 0.8 0.13 12.2 0.0 4.2 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 GAO88683.1 - 0.00083 18.7 0.7 0.32 10.5 0.0 4.2 5 0 0 5 5 5 1 PPR repeat cwf18 PF08315.7 GAO88684.1 - 1.2e-42 145.4 9.1 1.2e-42 145.4 6.3 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.2 GAO88685.1 - 9.4e-21 74.1 2.9 9.4e-21 74.1 2.0 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 GAO88685.1 - 1.5e-07 30.9 0.0 3.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.14 GAO88686.1 - 1.3e-34 118.6 0.0 2.2e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 DUF2854 PF11016.3 GAO88686.1 - 0.11 12.0 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) ADH_zinc_N_2 PF13602.1 GAO88688.1 - 0.14 13.0 1.4 0.28 12.0 0.7 1.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Ribosom_S12_S23 PF00164.20 GAO88689.1 - 3.7e-41 139.3 0.4 4.4e-41 139.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 GAO88690.1 - 1.5e-62 211.1 0.2 1.8e-60 204.3 0.1 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.13 GAO88691.1 - 3e-53 179.7 0.0 4.4e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.14 GAO88692.1 - 4.6e-30 104.6 0.0 5.9e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 GAO88692.1 - 0.00087 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain adh_short PF00106.20 GAO88692.1 - 0.061 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 GAO88692.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 KR domain DDE_Tnp_1_4 PF13701.1 GAO88692.1 - 0.14 10.3 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 Metallophos_2 PF12850.2 GAO88693.1 - 2.7e-15 56.5 0.0 3.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HECT PF00632.20 GAO88694.1 - 1.8e-93 313.2 0.0 2.6e-93 312.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 GAO88694.1 - 2e-33 113.8 20.6 1.1e-11 44.3 2.7 3.7 3 0 0 3 3 3 3 WW domain RRM_1 PF00076.17 GAO88694.1 - 1.5e-15 56.5 0.0 3.6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.25 GAO88694.1 - 4.7e-15 55.2 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_6 PF14259.1 GAO88694.1 - 2.2e-13 49.9 0.0 5.8e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88694.1 - 7.7e-05 22.4 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 GAO88694.1 - 0.34 8.7 1.1 0.45 8.3 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 GAO88694.1 - 0.49 9.3 3.3 0.73 8.8 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CASP_C PF08172.7 GAO88694.1 - 0.54 9.2 5.3 0.14 11.1 0.1 2.4 3 0 0 3 3 3 0 CASP C terminal IncA PF04156.9 GAO88694.1 - 0.7 9.4 3.9 1.2 8.6 2.7 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 GAO88694.1 - 1.5 8.3 5.1 3.7 7.1 3.5 1.7 1 0 0 1 1 1 0 Septum formation initiator MMR1 PF08505.5 GAO88695.1 - 0.038 14.0 1.9 0.052 13.5 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Gly-zipper_OmpA PF13436.1 GAO88695.1 - 0.12 11.9 11.7 0.019 14.5 4.0 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain CFEM PF05730.6 GAO88695.1 - 0.75 9.6 11.3 2.4 8.0 7.8 2.1 1 1 0 1 1 1 0 CFEM domain HsbA PF12296.3 GAO88695.1 - 6.6 6.6 12.5 16 5.3 0.3 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A peroxidase PF00141.18 GAO88696.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.6 2 0 0 2 2 2 0 Peroxidase HHH PF00633.18 GAO88696.1 - 0.16 11.7 0.8 0.54 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2520 PF10728.4 GAO88697.1 - 0.14 11.6 0.4 0.33 10.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DUF202 PF02656.10 GAO88698.1 - 1.8e-12 47.2 5.1 1.8e-12 47.2 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 GAO88698.1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 GAO88698.1 - 4.6 6.6 7.3 1.8 7.9 2.3 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 GAO88699.1 - 7.1e-35 118.9 0.0 8.2e-35 118.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.27 GAO88700.1 - 5.1e-45 149.8 14.1 7.2e-12 44.7 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAO88700.1 - 5.9e-08 31.3 2.1 0.13 10.3 0.0 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Hira PF07569.6 GAO88700.1 - 0.022 13.9 0.6 2.5 7.2 0.0 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split DUF3312 PF11768.3 GAO88700.1 - 0.041 12.1 0.0 0.08 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 GAO88700.1 - 0.065 11.9 0.3 3.6 6.2 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like DUF3540 PF12059.3 GAO88701.1 - 1 8.9 2.9 10 5.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) SUR7 PF06687.7 GAO88702.1 - 7.2e-52 176.0 9.2 8.5e-52 175.7 6.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arteri_Gl PF00951.13 GAO88702.1 - 0.76 9.3 4.5 0.35 10.4 0.7 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF2207 PF09972.4 GAO88702.1 - 4.8 5.6 8.9 1.3 7.5 2.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fig1 PF12351.3 GAO88702.1 - 5.2 6.9 14.8 0.81 9.5 6.9 2.0 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3869 PF12985.2 GAO88703.1 - 0.24 11.8 6.0 0.73 10.2 4.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3869) Acetyltransf_1 PF00583.19 GAO88704.1 - 1.6e-13 50.4 0.1 2.6e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO88704.1 - 6.9e-07 28.9 0.1 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAO88704.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO88704.1 - 0.0079 16.0 0.3 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO88704.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.1 GAO88705.1 - 0.0014 18.6 0.5 0.0076 16.3 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) IncA PF04156.9 GAO88705.1 - 3.1 7.3 6.4 11 5.5 4.5 2.0 1 1 0 1 1 1 0 IncA protein HEAT PF02985.17 GAO88706.1 - 5.1e-10 38.5 2.3 0.022 14.7 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 GAO88706.1 - 6e-10 38.7 0.0 1.6e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88706.1 - 3.7e-07 29.4 0.0 7.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 GAO88706.1 - 7.7e-05 23.0 0.1 0.18 12.3 0.0 3.4 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 GAO88706.1 - 0.0018 18.4 0.0 0.18 12.0 0.0 3.4 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.1 GAO88706.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 GAO88706.1 - 0.072 11.4 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.2 GAO88706.1 - 0.077 12.8 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CoA_trans PF01144.18 GAO88706.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase Ipi1_N PF12333.3 GAO88706.1 - 0.18 11.8 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation LsmAD PF06741.8 GAO88707.1 - 1.3e-28 98.8 0.9 1.3e-28 98.8 0.6 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 GAO88707.1 - 8.5e-19 67.2 0.0 2.3e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 GAO88708.1 - 9.5e-159 528.8 5.6 9.5e-159 528.8 3.9 1.9 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 GAO88708.1 - 0.00042 19.7 0.1 0.0012 18.2 0.1 1.9 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 GAO88708.1 - 1.4 8.7 5.5 0.88 9.3 0.4 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.1 GAO88708.1 - 3.9 7.5 9.4 3.2 7.8 0.0 3.5 4 0 0 4 4 4 0 Syntaxin-like protein SOG2 PF10428.4 GAO88709.1 - 0.0039 15.9 2.1 0.0043 15.7 1.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Mito_carr PF00153.22 GAO88710.1 - 7.6e-69 227.4 2.1 5.7e-26 90.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 GAO88710.1 - 0.028 14.3 3.0 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Uperin family DUF3320 PF11784.3 GAO88710.1 - 0.095 12.2 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) HLH PF00010.21 GAO88711.1 - 1.1e-12 47.4 0.0 3.8e-12 45.6 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain tRNA_lig_CPD PF08302.6 GAO88712.1 - 4.4e-105 350.5 0.0 6.3e-105 350.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 GAO88712.1 - 2.8e-84 282.0 0.0 5.8e-84 280.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 GAO88712.1 - 3e-50 170.3 0.0 5.9e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 GAO88712.1 - 0.032 14.0 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_5 PF13857.1 GAO88713.1 - 3.6e-14 52.4 0.5 6.1e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO88713.1 - 4.2e-09 36.6 0.3 3e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAO88713.1 - 1.8e-06 27.4 1.4 0.00031 20.4 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAO88713.1 - 5e-06 26.7 0.5 0.00044 20.5 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO88713.1 - 2.3e-05 24.1 0.9 0.00028 20.8 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 GAO88713.1 - 0.0081 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 YejG-like protein Mod_r PF07200.8 GAO88714.1 - 1.5e-11 44.4 8.8 2.1e-11 43.9 6.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein KIAA1430 PF13879.1 GAO88714.1 - 0.075 13.4 3.2 0.16 12.4 2.2 1.5 1 0 0 1 1 1 0 KIAA1430 homologue PAP2 PF01569.16 GAO88715.1 - 6.1e-23 80.9 4.0 6.1e-23 80.9 2.8 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF441 PF04284.8 GAO88715.1 - 0.00022 21.0 0.8 0.00052 19.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF441) Ytp1 PF10355.4 GAO88715.1 - 0.041 13.0 0.1 0.041 13.0 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (Ytp1) Aldo_ket_red PF00248.16 GAO88716.1 - 2.6e-55 187.2 0.1 3e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 GAO88717.1 - 4e-12 45.9 0.2 6.2e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NPR3 PF03666.8 GAO88718.1 - 1.2e-140 469.1 0.6 9.5e-138 459.5 0.0 2.4 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 GAO88718.1 - 0.0021 16.8 0.0 0.0042 15.8 0.0 1.4 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Mago-bind PF09282.5 GAO88718.1 - 4.9 6.8 8.0 0.5 9.9 1.4 2.5 2 0 0 2 2 2 0 Mago binding La PF05383.12 GAO88719.1 - 1.1e-20 73.1 0.1 1.9e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 La domain Statherin PF03875.8 GAO88719.1 - 0.76 9.6 5.7 2.1 8.3 3.9 1.8 1 0 0 1 1 1 0 Statherin Band_7 PF01145.20 GAO88720.1 - 6e-31 107.7 0.5 1.4e-30 106.5 0.4 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family DRTGG PF07085.7 GAO88720.1 - 0.03 13.9 1.5 0.87 9.2 0.1 2.6 2 0 0 2 2 2 0 DRTGG domain Band_7_1 PF13421.1 GAO88720.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family Hira PF07569.6 GAO88721.1 - 4.7e-83 277.7 0.0 1.1e-82 276.5 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 GAO88721.1 - 7.3e-40 133.4 21.8 2e-07 30.6 0.0 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat YchF-GTPase_C PF06071.8 GAO88721.1 - 8e-33 112.0 0.5 1.7e-32 111.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAO88721.1 - 7.8e-12 45.1 0.0 2.3e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase HIRA_B PF09453.5 GAO88721.1 - 1.9e-09 36.8 0.0 3.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 GAO88721.1 - 0.00024 20.6 0.2 2.4 7.9 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat FeoB_N PF02421.13 GAO88721.1 - 0.0015 17.8 0.0 0.0039 16.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 GAO88721.1 - 0.0053 16.5 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 TGS domain TFIIIC_delta PF12657.2 GAO88721.1 - 0.095 12.4 1.6 0.7 9.5 0.5 2.7 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 GAO88721.1 - 0.15 9.7 0.1 0.76 7.5 0.0 1.8 2 0 0 2 2 2 0 IKI3 family AAA_14 PF13173.1 GAO88721.1 - 0.22 11.4 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PUA PF01472.15 GAO88722.1 - 2.7e-15 55.8 0.1 4.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 GAO88723.1 - 1e-94 316.7 0.1 1.5e-94 316.2 0.1 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 GAO88724.1 - 2.2e-22 78.4 6.4 2.9e-18 65.2 1.1 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAO88724.1 - 1.9e-17 62.0 4.3 1.6e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAO88724.1 - 4.6e-15 54.2 5.5 0.00011 21.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAO88724.1 - 4.5e-09 36.7 6.0 6.7e-06 26.6 1.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO88724.1 - 1.6e-08 33.7 0.3 0.099 12.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO88724.1 - 3.1e-07 30.4 3.2 0.13 12.9 0.3 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAO88724.1 - 1.2e-06 28.1 3.4 0.00052 20.0 0.1 3.4 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO88724.1 - 1.1e-05 25.6 1.2 0.00037 20.7 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO88724.1 - 2.7e-05 24.0 5.8 0.03 14.2 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAO88724.1 - 0.00013 21.4 6.6 0.1 12.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAO88724.1 - 0.00016 21.4 1.3 0.029 14.2 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 GAO88724.1 - 0.022 14.2 4.1 0.022 14.2 2.8 2.1 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.13 GAO88724.1 - 0.048 13.5 0.3 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 GAO88724.1 - 0.18 11.7 5.6 3.4 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO88724.1 - 0.63 10.6 8.5 3.4 8.3 0.4 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat DHHA1 PF02272.14 GAO88724.1 - 1.6 8.4 7.8 3.8 7.2 0.0 3.0 2 1 0 2 2 2 0 DHHA1 domain Tim44 PF04280.10 GAO88725.1 - 3.9e-34 117.7 0.1 1.4e-33 115.9 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain VPS9 PF02204.13 GAO88726.1 - 1.7e-17 63.3 0.0 4.7e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 GAO88726.1 - 2.8e-16 59.1 0.1 5.8e-11 42.2 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO88726.1 - 3.3e-12 46.5 0.0 1.9e-07 31.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO88726.1 - 5.2e-10 39.5 0.0 0.0021 18.5 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88726.1 - 4.6e-08 32.5 0.0 8.5 6.9 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat PX PF00787.19 GAO88726.1 - 2.2e-07 30.6 2.2 2.2e-07 30.6 0.2 2.1 2 0 0 2 2 2 1 PX domain Ribosomal_S11 PF00411.14 GAO88726.1 - 1.2e-06 28.6 0.0 3.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S11 Ank PF00023.25 GAO88726.1 - 6.1e-06 25.7 0.2 0.11 12.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat 7TM_GPCR_Srw PF10324.4 GAO88727.1 - 0.0096 15.0 0.1 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw gpUL132 PF11359.3 GAO88727.1 - 0.012 14.9 1.5 0.018 14.3 1.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Herpes_gE PF02480.11 GAO88727.1 - 0.02 13.1 0.3 0.03 12.5 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_glycop PF01528.11 GAO88727.1 - 0.094 11.4 0.1 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M HemY_N PF07219.8 GAO88727.1 - 0.11 12.0 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Inhibitor_I78 PF11720.3 GAO88728.1 - 1.4e-14 53.5 0.0 1.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 GAO88728.1 - 0.0098 16.0 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family Alpha-L-AF_C PF06964.7 GAO88729.1 - 4.1e-37 127.6 0.0 6.7e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 GAO88730.1 - 1.5e-84 284.1 20.9 2.3e-56 191.2 2.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO88730.1 - 9.8e-31 106.7 19.7 7.3e-20 70.9 8.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Nefa_Nip30_N PF10187.4 GAO88731.1 - 4.1e-32 110.3 14.3 4.1e-32 110.3 9.9 2.0 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 GAO88731.1 - 0.02 13.8 2.9 0.025 13.5 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aldo_ket_red PF00248.16 GAO88732.1 - 8.7e-49 165.8 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.12 GAO88734.1 - 7e-57 193.1 1.2 7e-35 120.8 0.5 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 6 CK_II_beta PF01214.13 GAO88735.1 - 2.6e-71 238.9 0.1 2.6e-71 238.9 0.1 1.4 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Abhydrolase_6 PF12697.2 GAO88736.1 - 4e-07 30.1 2.8 5.1e-07 29.8 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO88736.1 - 0.00015 21.4 2.4 0.00039 20.1 1.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO88736.1 - 0.00082 18.9 0.5 0.0099 15.4 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAO88736.1 - 0.014 14.9 0.5 0.046 13.2 0.3 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold JAB PF01398.16 GAO88737.1 - 1.6e-08 34.2 0.4 3.4e-07 29.9 0.3 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_XkdX PF09693.5 GAO88737.1 - 0.062 12.8 0.2 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) GDE_N PF12439.3 GAO88737.1 - 0.13 11.4 0.9 1.5 8.0 0.2 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Mito_carr PF00153.22 GAO88738.1 - 1.2e-43 146.7 4.0 2.2e-18 65.7 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Trypan_PARP PF05887.6 GAO88739.1 - 0.00096 18.9 31.2 0.00096 18.9 21.6 15.1 5 4 6 12 12 12 5 Procyclic acidic repetitive protein (PARP) RNase_H PF00075.19 GAO88740.1 - 2.5e-14 53.7 0.1 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAO88740.1 - 0.0003 20.4 0.4 0.0062 16.2 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase-like HMG_box PF00505.14 GAO88742.1 - 1.4e-10 41.2 1.9 1.4e-10 41.2 1.3 2.9 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAO88742.1 - 1.5e-09 38.0 2.2 1.5e-09 38.0 1.5 3.3 3 0 0 3 3 3 2 HMG-box domain Di19_C PF14571.1 GAO88742.1 - 0.00078 19.7 5.0 0.00079 19.7 1.4 2.3 2 0 0 2 2 2 1 Stress-induced protein Di19, C-terminal eIF-3c_N PF05470.7 GAO88742.1 - 0.011 13.8 5.6 0.015 13.3 3.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF106 PF01956.11 GAO88742.1 - 0.53 9.8 2.0 1.1 8.7 1.4 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 DEAD PF00270.24 GAO88743.1 - 2.2e-46 157.4 0.0 5e-46 156.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO88743.1 - 1.9e-24 85.3 0.0 5.2e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAO88743.1 - 0.0014 17.4 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAO88743.1 - 0.019 14.8 0.0 0.15 11.9 0.0 2.5 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit SIMPL PF04402.9 GAO88744.1 - 2.4 7.9 11.4 4.4 7.1 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) zf-H2C2_2 PF13465.1 GAO88745.1 - 7.7e-13 48.0 39.4 5.9e-07 29.4 0.3 7.2 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAO88745.1 - 5.4e-11 42.1 40.0 3.4e-06 27.0 0.6 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO88745.1 - 8.8e-07 28.8 46.7 0.00074 19.6 0.5 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAO88745.1 - 2.1e-06 27.4 8.4 0.015 15.2 0.4 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO88745.1 - 5.4e-06 26.3 11.4 0.0016 18.5 0.2 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO88745.1 - 4.1e-05 23.6 15.9 0.0011 19.0 0.2 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Adeno_E1A PF02703.9 GAO88746.1 - 0.35 10.2 1.6 0.56 9.6 0.2 1.8 1 1 1 2 2 2 0 Early E1A protein DUF883 PF05957.8 GAO88746.1 - 1.3 9.4 4.4 11 6.5 0.3 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) adh_short PF00106.20 GAO88747.1 - 6.8e-27 94.4 0.1 1.1e-26 93.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO88747.1 - 2.8e-18 66.5 0.0 1.1e-17 64.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO88747.1 - 1.4e-12 47.6 0.1 2.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO88747.1 - 2.5e-05 23.8 0.0 6.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIM-br_sig_trns PF09370.5 GAO88748.1 - 4.1e-136 452.3 0.6 4.6e-136 452.1 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 GAO88748.1 - 1.7e-05 24.1 0.3 2.8e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Amidohydro_2 PF04909.9 GAO88748.1 - 0.0066 16.0 0.1 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase PcrB PF01884.12 GAO88748.1 - 0.061 12.5 1.3 6.7 5.8 0.1 2.3 2 0 0 2 2 2 0 PcrB family DUF2122 PF09895.4 GAO88748.1 - 0.088 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Glyco_hydro_3_C PF01915.17 GAO88748.1 - 0.11 11.9 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain UPF0261 PF06792.6 GAO88749.1 - 5.8e-157 522.2 2.0 6.9e-157 522.0 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) AdoHcyase PF05221.12 GAO88750.1 - 5.8e-137 454.9 0.0 6.7e-137 454.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 GAO88750.1 - 1.1e-85 285.4 2.1 1.8e-85 284.7 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAO88750.1 - 2.7e-07 29.9 0.1 5.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 GAO88750.1 - 0.00025 20.4 0.2 0.00046 19.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 GAO88750.1 - 0.00055 19.9 0.1 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 GAO88750.1 - 0.026 14.0 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_23 PF13489.1 GAO88752.1 - 1.7e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO88752.1 - 9.5e-10 38.2 0.0 8.2e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO88752.1 - 1.1e-06 29.1 0.5 1.8e-05 25.2 0.1 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO88752.1 - 1.2e-06 28.9 0.0 3.4e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO88752.1 - 0.00017 22.0 0.1 0.00089 19.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO88752.1 - 0.0029 17.9 0.0 0.0089 16.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAO88752.1 - 0.0036 16.9 0.0 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO88752.1 - 0.011 14.8 0.1 0.14 11.2 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO88752.1 - 0.084 12.9 0.1 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain UbiA PF01040.13 GAO88753.1 - 1.4e-20 73.6 12.2 1.4e-20 73.6 8.5 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family PhyH PF05721.8 GAO88754.1 - 7.4e-08 32.6 0.0 2.4e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2379 PF09543.5 GAO88754.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Prp31_C PF09785.4 GAO88756.1 - 8.8e-45 152.1 0.2 1.6e-44 151.2 0.1 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 GAO88756.1 - 5.4e-40 136.1 0.1 1.2e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAO88756.1 - 4.6e-16 58.3 0.0 8.4e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain TPR_14 PF13428.1 GAO88757.1 - 2.1e-25 86.8 13.8 0.0011 19.3 0.0 11.9 6 2 6 12 12 11 5 Tetratricopeptide repeat HAT PF02184.11 GAO88757.1 - 1.1e-22 79.4 81.5 3.1e-14 52.4 3.4 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 GAO88757.1 - 3.7e-21 75.2 0.3 0.00062 20.0 0.0 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAO88757.1 - 1.4e-20 73.3 11.8 0.0037 17.9 0.0 8.7 9 1 1 10 10 9 4 Tetratricopeptide repeat Suf PF05843.9 GAO88757.1 - 2.7e-18 66.6 18.6 0.00014 21.7 0.3 6.0 2 1 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_17 PF13431.1 GAO88757.1 - 1.3e-09 37.4 2.3 0.02 15.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO88757.1 - 5.9e-09 35.4 2.5 0.54 9.9 0.0 6.2 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 GAO88757.1 - 4.6e-08 32.3 15.4 0.25 11.3 0.0 9.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO88757.1 - 1.3e-06 28.2 13.4 0.12 12.2 0.0 8.2 10 0 0 10 10 10 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 GAO88757.1 - 3.8e-06 26.5 21.6 0.012 15.2 1.4 6.9 4 2 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 GAO88757.1 - 0.00068 19.2 14.0 8 6.5 0.1 7.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO88757.1 - 0.0031 17.0 2.4 5.2 6.8 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAO88757.1 - 0.019 15.3 21.5 3.8 8.1 0.0 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAO88757.1 - 3 7.7 9.8 6.4 6.7 0.3 5.0 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 GAO88757.1 - 3.2 6.5 34.2 0.19 10.5 0.1 7.3 4 4 1 6 6 6 0 NRDE-2, necessary for RNA interference TMEM154 PF15102.1 GAO88758.1 - 0.0066 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Kelch_5 PF13854.1 GAO88758.1 - 0.017 15.0 2.9 18 5.4 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Podoplanin PF05808.6 GAO88758.1 - 0.018 14.5 1.5 0.053 13.0 1.0 1.8 1 0 0 1 1 1 0 Podoplanin MtrG PF04210.8 GAO88758.1 - 0.21 11.2 0.5 0.37 10.4 0.3 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Rick_17kDa_Anti PF05433.10 GAO88758.1 - 0.32 10.6 4.2 0.085 12.5 0.3 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAO88758.1 - 5 6.8 6.7 0.41 10.3 0.9 1.9 2 0 0 2 2 2 0 Glycine zipper CAF-1_p150 PF11600.3 GAO88759.1 - 0.0034 16.7 13.8 0.0034 16.7 9.6 3.0 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1691 PF07950.6 GAO88759.1 - 0.062 13.2 0.1 4.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) DUF533 PF04391.7 GAO88759.1 - 1 8.6 15.4 2.1 7.6 0.1 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF533) zf-C2H2_4 PF13894.1 GAO88760.1 - 1.8e-08 34.1 9.9 9.2e-06 25.6 1.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO88760.1 - 3.5e-08 33.3 9.6 4.7e-06 26.6 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO88760.1 - 3e-06 27.2 16.1 5.1e-06 26.5 1.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 GAO88760.1 - 2.7e-05 24.1 7.4 0.00047 20.2 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 GAO88760.1 - 0.0023 18.0 5.6 0.0042 17.1 3.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.4 GAO88760.1 - 0.0035 16.8 0.3 0.0055 16.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 GAO88760.1 - 0.0042 17.1 0.9 0.0042 17.1 0.6 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.6 GAO88760.1 - 0.032 14.4 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-C2H2_2 PF12756.2 GAO88760.1 - 0.076 13.1 0.9 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PRP21_like_P PF12230.3 GAO88760.1 - 0.14 11.6 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-BED PF02892.10 GAO88760.1 - 9.8 6.0 12.3 0.64 9.8 4.6 1.9 2 0 0 2 2 2 0 BED zinc finger Aldo_ket_red PF00248.16 GAO88761.1 - 1.3e-60 204.6 0.0 1.6e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 GAO88762.1 - 8.7e-08 32.0 5.9 1.2e-06 28.5 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO88762.1 - 2.3e-05 24.4 8.5 0.00031 20.8 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO88762.1 - 3.1e-05 24.0 0.3 3.1e-05 24.0 0.2 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAO88762.1 - 0.017 15.0 0.3 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO88762.1 - 1.3 9.2 5.6 1.2 9.3 0.3 2.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 GAO88763.1 - 1.2e-68 231.1 0.1 1.8e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 GAO88763.1 - 1.5e-23 82.1 2.0 7.3e-14 51.1 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAO88763.1 - 1.8e-15 56.5 0.0 7.8e-15 54.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 GAO88763.1 - 2.1e-11 43.9 0.0 6.3e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.3 GAO88763.1 - 1.5e-07 30.5 0.0 3.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ABC_tran PF00005.22 GAO88764.1 - 7.6e-35 120.1 0.0 1.7e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 GAO88764.1 - 2.1e-14 52.7 5.6 2.1e-14 52.7 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 GAO88764.1 - 8e-14 52.2 2.1 0.0032 17.5 0.6 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 GAO88764.1 - 8.9e-11 41.4 2.4 0.0011 18.2 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 GAO88764.1 - 1.9e-06 27.2 0.0 2.9 6.8 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 GAO88764.1 - 5.2e-06 27.2 0.1 0.17 12.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAO88764.1 - 3.5e-05 23.9 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAO88764.1 - 4.1e-05 23.7 0.0 0.042 14.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.22 GAO88764.1 - 7.7e-05 22.1 2.5 7.7e-05 22.1 1.7 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain DUF258 PF03193.11 GAO88764.1 - 8.7e-05 21.7 0.9 0.49 9.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAO88764.1 - 0.0001 21.7 0.2 0.072 12.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAO88764.1 - 0.00017 21.9 0.0 0.32 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO88764.1 - 0.00027 20.8 0.1 0.023 14.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 GAO88764.1 - 0.00079 19.0 0.2 0.0096 15.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 GAO88764.1 - 0.0014 19.0 0.0 0.1 13.1 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein Fer4_21 PF14697.1 GAO88764.1 - 0.0014 18.3 11.4 0.0029 17.4 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain MobB PF03205.9 GAO88764.1 - 0.0018 17.9 0.8 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 GAO88764.1 - 0.0018 17.7 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E AAA_16 PF13191.1 GAO88764.1 - 0.0035 17.3 0.1 1.2 9.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAO88764.1 - 0.0045 17.1 0.4 1.8 8.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_6 PF12837.2 GAO88764.1 - 0.0046 16.7 11.0 0.0098 15.7 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_23 PF13476.1 GAO88764.1 - 0.0058 16.9 0.2 0.36 11.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAO88764.1 - 0.0071 15.8 2.3 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 GAO88764.1 - 0.0079 15.8 1.9 0.57 9.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.1 GAO88764.1 - 0.0085 14.6 1.1 0.011 14.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 GAO88764.1 - 0.01 15.2 0.1 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.1 GAO88764.1 - 0.015 15.1 1.4 0.015 15.1 0.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Rad17 PF03215.10 GAO88764.1 - 0.02 13.6 0.0 0.069 11.8 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 GAO88764.1 - 0.024 14.6 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAO88764.1 - 0.039 13.6 0.1 2 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_16 PF13484.1 GAO88764.1 - 0.048 14.4 0.1 0.048 14.4 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain SbcCD_C PF13558.1 GAO88764.1 - 0.084 12.7 0.0 14 5.7 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 GAO88764.1 - 0.089 12.2 1.6 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.12 GAO88764.1 - 0.097 12.0 0.3 15 4.8 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.17 GAO88764.1 - 0.12 11.2 0.1 11 4.8 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain Fer4_8 PF13183.1 GAO88764.1 - 0.15 12.1 8.4 0.56 10.2 5.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain KaiC PF06745.8 GAO88764.1 - 0.16 11.0 0.0 0.4 9.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 GAO88764.1 - 0.27 10.8 1.3 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 GAO88764.1 - 0.31 11.3 12.8 0.062 13.5 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAO88764.1 - 0.4 11.1 13.3 0.043 14.2 1.4 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAO88764.1 - 1.4 8.9 12.8 0.56 10.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 GAO88765.1 - 1.7e-61 203.9 23.8 2.5e-15 56.1 0.0 7.3 6 1 0 6 6 6 6 FF domain WW PF00397.21 GAO88765.1 - 1.6e-18 66.1 10.7 3.2e-09 36.4 0.3 2.5 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 GAO88766.1 - 9e-102 340.4 0.0 1.2e-101 340.0 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 GAO88767.1 - 5.3e-22 77.2 0.3 5.3e-22 77.2 0.2 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF3989 PF13150.1 GAO88767.1 - 0.091 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) PGK PF00162.14 GAO88768.1 - 2.3e-150 500.4 0.7 2.7e-150 500.2 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DSS1_SEM1 PF05160.8 GAO88769.1 - 2.8e-24 84.6 12.8 2.8e-24 84.6 8.9 1.5 2 0 0 2 2 2 1 DSS1/SEM1 family DUF2947 PF11163.3 GAO88769.1 - 0.35 10.4 4.2 0.38 10.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF3808 PF10300.4 GAO88770.1 - 1.9e-164 547.7 0.0 2.4e-164 547.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 GAO88770.1 - 0.0056 16.2 3.3 0.5 10.0 0.9 3.4 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 GAO88770.1 - 0.81 9.7 7.8 28 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO88770.1 - 1.8 9.3 6.7 1.1 10.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 GAO88771.1 - 1.7e-35 122.4 35.7 1.7e-35 122.4 24.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 GAO88772.1 - 9e-296 979.6 0.0 2.2e-89 299.7 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 GAO88772.1 - 1.3e-264 874.6 0.0 4.4e-49 166.9 0.0 9.4 9 0 0 9 9 9 9 Condensation domain PP-binding PF00550.20 GAO88772.1 - 4.9e-53 177.2 0.4 1.4e-10 41.2 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO88772.1 - 1.5e-10 41.8 0.2 0.0057 17.5 0.0 4.9 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAO88772.1 - 0.00051 18.6 0.0 0.75 8.1 0.0 2.7 2 0 0 2 2 2 2 Transferase family ABC_tran PF00005.22 GAO88773.1 - 4.6e-49 166.2 0.8 6.1e-27 94.5 0.1 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO88773.1 - 6.9e-35 120.7 23.9 4.4e-28 98.4 8.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAO88773.1 - 2.9e-11 43.9 0.1 0.0038 17.2 0.0 4.0 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 GAO88773.1 - 7.4e-09 35.1 6.9 0.0093 15.2 0.1 4.6 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAO88773.1 - 5.3e-08 33.0 0.8 0.024 14.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO88773.1 - 5.7e-08 32.9 0.1 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAO88773.1 - 2.7e-07 30.1 0.0 0.00082 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO88773.1 - 6.3e-07 28.8 1.8 0.00029 20.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO88773.1 - 4.2e-06 26.0 0.1 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO88773.1 - 4.3e-06 27.2 0.1 0.037 14.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein ATP-synt_ab PF00006.20 GAO88773.1 - 7.3e-06 25.6 0.3 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 GAO88773.1 - 8.2e-06 26.2 6.4 0.0013 19.0 0.4 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAO88773.1 - 1.1e-05 25.3 0.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 GAO88773.1 - 1.3e-05 25.1 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAO88773.1 - 2.2e-05 24.2 0.0 0.02 14.5 0.0 3.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 GAO88773.1 - 2.9e-05 24.8 0.7 0.058 14.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAO88773.1 - 3.6e-05 23.3 2.3 0.0085 15.5 0.1 2.8 2 1 1 3 3 3 1 AAA-like domain AAA PF00004.24 GAO88773.1 - 5.7e-05 23.3 0.1 0.12 12.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 GAO88773.1 - 0.00014 20.7 0.3 0.013 14.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain T2SE PF00437.15 GAO88773.1 - 0.00017 20.6 0.0 0.042 12.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 GAO88773.1 - 0.00037 20.6 0.2 0.5 10.5 0.0 3.2 4 0 0 4 4 2 1 RNA helicase MobB PF03205.9 GAO88773.1 - 0.0004 20.0 1.0 0.98 9.1 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 GAO88773.1 - 0.00062 19.6 0.1 0.79 9.6 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.13 GAO88773.1 - 0.00071 19.1 0.1 0.099 12.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 GAO88773.1 - 0.00084 18.9 0.7 0.82 9.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAO88773.1 - 0.0014 17.7 0.3 1.4 7.9 0.0 2.5 3 0 0 3 3 2 2 Zeta toxin NACHT PF05729.7 GAO88773.1 - 0.0014 18.2 0.0 0.31 10.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 GAO88773.1 - 0.0015 18.0 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 GAO88773.1 - 0.0016 18.7 0.1 1.4 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 GAO88773.1 - 0.0021 16.7 4.0 0.0075 14.8 0.8 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class cobW PF02492.14 GAO88773.1 - 0.007 15.8 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 GAO88773.1 - 0.019 13.9 0.3 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 GAO88773.1 - 0.02 14.4 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 GAO88773.1 - 0.022 14.6 0.0 0.57 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAO88773.1 - 0.026 13.9 0.7 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 GAO88773.1 - 0.027 14.1 1.0 5.5 6.6 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 GAO88773.1 - 0.042 13.5 1.6 3.9 7.2 0.1 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 GAO88773.1 - 0.049 12.9 1.2 5.4 6.2 0.1 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_15 PF13175.1 GAO88773.1 - 0.071 12.1 0.0 0.41 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 GAO88773.1 - 0.076 12.8 1.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_11 PF13086.1 GAO88773.1 - 0.084 12.4 0.0 9.2 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAO88773.1 - 0.13 12.0 1.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 GAO88773.1 - 0.17 10.8 0.5 3.2 6.6 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Rad17 PF03215.10 GAO88773.1 - 0.3 9.7 0.3 0.49 9.0 0.2 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 GAO88773.1 - 0.37 9.4 0.0 0.99 7.9 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein Nup160 PF11715.3 GAO88774.1 - 8.4e-163 542.4 2.4 1.2e-162 541.8 1.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 GAO88775.1 - 4.6e-119 396.0 1.2 1.7e-83 279.4 0.0 2.2 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.1 GAO88775.1 - 6.1e-08 32.3 0.8 3e-06 26.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain HHH_5 PF14520.1 GAO88775.1 - 1.4e-07 31.5 0.1 3.6e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 GAO88775.1 - 7.6e-06 25.2 0.2 2.1e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 GAO88775.1 - 0.00017 20.7 0.6 0.0037 16.4 0.4 2.4 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.10 GAO88775.1 - 0.05 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 GAO88775.1 - 0.062 12.1 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein CDC27 PF09507.5 GAO88777.1 - 0.57 9.3 30.7 0.66 9.1 21.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.7 GAO88777.1 - 1.7 8.3 25.9 2.1 8.0 17.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 GAO88777.1 - 1.8 6.9 26.6 2.2 6.6 18.4 1.0 1 0 0 1 1 1 0 Daxx Family Dicty_REP PF05086.7 GAO88777.1 - 2.5 5.7 12.5 3.2 5.3 8.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.7 GAO88777.1 - 2.5 5.8 28.5 2.7 5.7 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 GAO88777.1 - 3 7.0 15.6 3.7 6.7 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein ORC6 PF05460.8 GAO88777.1 - 6.1 5.8 16.0 6.9 5.6 11.1 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM60A PF15396.1 GAO88777.1 - 8.1 6.1 12.2 10 5.7 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CPL PF08144.6 GAO88778.1 - 6.1e-16 58.5 0.1 1.2e-14 54.3 0.0 3.2 4 0 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 GAO88778.1 - 0.016 14.6 0.1 10 5.8 0.0 3.2 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Phage_base_V PF04717.7 GAO88778.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage-related baseplate assembly protein DUF4268 PF14088.1 GAO88781.1 - 0.039 13.5 0.2 0.049 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Dicty_REP PF05086.7 GAO88781.1 - 0.16 9.6 4.2 0.19 9.4 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-BED PF02892.10 GAO88782.1 - 0.0059 16.3 0.3 0.0059 16.3 0.2 1.8 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 GAO88782.1 - 0.0099 15.7 6.8 0.023 14.5 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B_palm PF14792.1 GAO88783.1 - 5.4e-31 106.9 0.0 1.1e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 GAO88783.1 - 1.4e-22 79.1 0.3 6.1e-22 77.0 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 GAO88783.1 - 1.4e-21 75.8 0.3 5.6e-21 73.8 0.1 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 GAO88783.1 - 3.3e-19 68.8 1.1 1.5e-18 66.7 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.21 GAO88783.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 GAO88783.1 - 0.0036 17.6 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 GAO88783.1 - 0.0055 16.8 0.1 0.14 12.3 0.0 2.7 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 GAO88783.1 - 0.046 13.4 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif ATP-synt_10 PF05176.9 GAO88784.1 - 1.2e-97 326.1 0.0 1.6e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 GAO88785.1 - 1.1e-14 54.2 7.9 2.4e-14 53.1 0.0 3.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus TcdB_N PF12918.2 GAO88785.1 - 0.018 15.0 0.3 0.42 10.7 0.2 2.7 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain IncA PF04156.9 GAO88785.1 - 0.049 13.2 11.3 0.088 12.4 7.9 1.4 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 GAO88785.1 - 0.061 11.7 1.4 0.066 11.6 1.0 1.1 1 0 0 1 1 1 0 AAA domain GOLGA2L5 PF15070.1 GAO88785.1 - 0.072 11.5 8.0 0.1 11.1 5.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Dor1 PF04124.7 GAO88785.1 - 0.14 10.5 5.7 0.23 9.9 3.9 1.3 1 0 0 1 1 1 0 Dor1-like family DUF4570 PF15134.1 GAO88785.1 - 0.16 11.8 4.4 0.27 11.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Peptidase_S46 PF10459.4 GAO88785.1 - 0.23 9.8 3.1 0.27 9.6 2.1 1.1 1 0 0 1 1 1 0 Peptidase S46 APG6 PF04111.7 GAO88785.1 - 0.32 10.0 6.6 0.44 9.5 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 GAO88785.1 - 1.2 7.4 4.4 1.6 7.0 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) PEP-utilisers_N PF05524.8 GAO88785.1 - 1.8 8.3 10.6 0.33 10.7 2.3 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Syntaxin-6_N PF09177.6 GAO88785.1 - 1.9 8.9 5.6 3.7 8.0 2.1 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Surfac_D-trimer PF09006.6 GAO88785.1 - 3.3 7.4 5.0 3.5 7.4 0.1 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation FUSC PF04632.7 GAO88785.1 - 7 4.9 8.1 8.6 4.6 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L29 PF00831.18 GAO88786.1 - 2.8e-20 71.7 0.8 2.8e-20 71.7 0.6 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.5 GAO88786.1 - 0.011 15.7 3.9 0.011 15.7 2.7 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3585 PF12130.3 GAO88786.1 - 0.012 15.4 5.8 0.015 15.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) DUF3418 PF11898.3 GAO88786.1 - 0.029 12.8 5.2 0.032 12.6 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) YlqD PF11068.3 GAO88786.1 - 1 9.4 6.1 0.22 11.5 1.4 1.8 1 1 1 2 2 2 0 YlqD protein CorA PF01544.13 GAO88786.1 - 1.1 8.2 4.2 1.4 7.9 2.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 GAO88786.1 - 1.3 9.4 8.2 0.12 12.6 1.6 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.12 GAO88786.1 - 1.7 8.2 5.5 2.6 7.7 0.7 2.6 2 1 1 3 3 3 0 Prefoldin subunit DUF3886 PF13025.1 GAO88786.1 - 2.2 8.3 8.0 2.8 7.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) IncA PF04156.9 GAO88786.1 - 2.4 7.7 5.7 3.6 7.1 4.0 1.2 1 0 0 1 1 1 0 IncA protein Med16 PF11635.3 GAO88787.1 - 9e-218 724.9 0.0 1.8e-217 723.9 0.0 1.4 1 1 1 2 2 2 1 Mediator complex subunit 16 SIR2 PF02146.12 GAO88788.1 - 1.7e-31 109.2 0.0 6.1e-31 107.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 GAO88788.1 - 0.015 15.2 7.4 0.066 13.1 1.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF479 PF04336.7 GAO88788.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF479 CBFD_NFYB_HMF PF00808.18 GAO88789.1 - 4.9e-05 23.2 0.0 9.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO88789.1 - 0.024 14.7 0.2 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 GN3L_Grn1 PF08701.6 GAO88790.1 - 4.7e-25 87.2 19.7 4.7e-25 87.2 13.6 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 GAO88790.1 - 4.5e-21 74.9 0.1 3.7e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO88790.1 - 1.9e-06 27.7 4.3 0.23 11.2 0.4 4.0 2 2 1 3 3 3 3 Dynamin family GTP_EFTU PF00009.22 GAO88790.1 - 5.2e-06 26.0 0.0 0.065 12.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAO88790.1 - 4.2e-05 22.8 0.1 0.00034 19.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAO88790.1 - 0.00014 21.1 0.2 0.00023 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO88790.1 - 0.00083 19.8 0.5 0.36 11.3 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein Nop14 PF04147.7 GAO88790.1 - 0.014 13.3 31.8 0.024 12.5 22.1 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_18 PF13238.1 GAO88790.1 - 0.024 14.9 0.0 0.024 14.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 GAO88790.1 - 0.03 13.1 0.0 0.03 13.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein SRPRB PF09439.5 GAO88790.1 - 0.058 12.5 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 GAO88790.1 - 0.062 12.3 0.1 0.65 9.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.1 GAO88790.1 - 0.14 12.1 3.0 0.56 10.1 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 GAO88790.1 - 0.22 12.3 0.0 0.22 12.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain Daxx PF03344.10 GAO88790.1 - 0.34 9.3 21.5 0.57 8.6 14.9 1.3 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 GAO88790.1 - 0.39 10.5 20.7 0.68 9.7 14.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.1 GAO88791.1 - 2.1e-13 50.8 0.0 4.4e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO88791.1 - 1.1e-08 35.7 0.0 1.1e-06 29.2 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO88791.1 - 1.3e-07 31.1 0.0 2.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 GAO88791.1 - 6.8e-05 23.1 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAO88791.1 - 0.023 14.5 0.0 7.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 GAO88792.1 - 7.4e-17 60.7 2.4 2.2e-16 59.1 1.7 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAO88792.1 - 2.3e-06 27.2 0.4 2.3e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain CDC45 PF02724.9 GAO88792.1 - 0.43 8.5 20.8 0.68 7.9 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Ly49 PF08391.5 GAO88792.1 - 5.1 7.2 5.3 9.5 6.3 3.7 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region SAPS PF04499.10 GAO88792.1 - 8.4 4.9 12.1 12 4.3 8.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein His_Phos_1 PF00300.17 GAO88793.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRC_subunit PF08624.5 GAO88794.1 - 4e-54 182.2 0.1 5.6e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit YL1 PF05764.8 GAO88795.1 - 0.084 12.4 1.4 0.092 12.3 1.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SLD3 PF08639.5 GAO88796.1 - 3e-173 577.0 6.4 3.9e-173 576.6 4.4 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 S-AdoMet_synt_C PF02773.11 GAO88797.1 - 1.3e-78 261.4 0.9 8.6e-78 258.7 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAO88797.1 - 4.3e-47 158.9 0.0 7.8e-47 158.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAO88797.1 - 6.1e-43 145.1 0.1 1.5e-42 143.9 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 GAO88798.1 - 1.5e-75 253.7 0.1 1.8e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAO88798.1 - 5.1e-06 27.3 0.0 2.1e-05 25.3 0.0 2.2 1 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAO88798.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAO88798.1 - 0.00028 20.3 0.0 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 GAO88798.1 - 0.0015 18.0 0.0 0.0048 16.3 0.0 2.0 1 1 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 GAO88798.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAO88798.1 - 0.0019 18.2 0.1 0.008 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAO88798.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 GAO88798.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAO88798.1 - 0.0038 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 GAO88798.1 - 0.0048 16.3 0.1 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO88798.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO88798.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 GAO88798.1 - 0.017 15.0 0.3 0.1 12.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAO88798.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAO88798.1 - 0.02 14.3 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 GAO88798.1 - 0.021 15.1 0.0 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 GAO88798.1 - 0.022 14.1 0.1 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain T2SE PF00437.15 GAO88798.1 - 0.026 13.4 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 GAO88798.1 - 0.029 14.6 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 GAO88798.1 - 0.056 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.18 GAO88798.1 - 0.069 13.1 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 GAO88798.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 GAO88798.1 - 0.087 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 FleQ PF06490.6 GAO88798.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ ArgK PF03308.11 GAO88798.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 GAO88798.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Apq12 PF12716.2 GAO88799.1 - 1.6e-18 66.1 15.2 2.2e-18 65.6 10.5 1.2 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Fungal_trans_2 PF11951.3 GAO88800.1 - 2.1e-58 197.7 5.2 2.6e-58 197.4 3.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_H_N PF03224.9 GAO88801.1 - 4.9e-84 282.1 0.0 6.2e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAO88801.1 - 1.9e-39 134.2 0.0 5.7e-39 132.7 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_EZ PF13513.1 GAO88801.1 - 0.45 11.0 4.3 7.8 7.1 0.0 4.1 4 1 1 5 5 5 0 HEAT-like repeat TMF_TATA_bd PF12325.3 GAO88802.1 - 2.5e-44 149.9 12.2 2.5e-44 149.9 8.5 7.4 3 2 2 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 GAO88802.1 - 3.2e-20 71.7 13.7 3.2e-20 71.7 9.5 10.7 5 3 5 10 10 10 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 GAO88802.1 - 5.2 7.3 23.4 1.9 8.8 1.6 5.5 5 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Ank_2 PF12796.2 GAO88803.1 - 1.5e-52 175.8 1.4 5.2e-20 71.5 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO88803.1 - 9.7e-38 127.8 4.4 1.5e-09 38.0 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 GAO88803.1 - 1e-34 116.6 0.4 3.1e-05 23.5 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAO88803.1 - 1.1e-34 117.6 0.3 1.1e-09 38.2 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88803.1 - 2.1e-29 98.6 0.5 0.00058 19.8 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.3 GAO88803.1 - 0.036 13.5 0.4 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels DUF1843 PF08898.5 GAO88803.1 - 0.061 13.3 0.6 8 6.5 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) WD40 PF00400.27 GAO88804.1 - 2.5e-55 182.4 10.7 2e-09 36.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAO88804.1 - 0.0026 15.9 3.8 8.4 4.3 0.0 4.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 AAA PF00004.24 GAO88805.1 - 6.7e-14 52.2 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO88805.1 - 3.3e-10 40.2 0.1 1.4e-09 38.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO88805.1 - 7e-09 35.9 0.0 3.5e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 GAO88805.1 - 4.7e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 GAO88805.1 - 4.8e-05 24.1 0.0 0.00033 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO88805.1 - 0.00088 18.9 0.3 0.0033 17.1 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAO88805.1 - 0.002 18.1 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAO88805.1 - 0.0042 16.6 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAO88805.1 - 0.0047 15.9 0.0 0.026 13.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 GAO88805.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_32 PF13654.1 GAO88805.1 - 0.02 13.5 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAO88805.1 - 0.024 14.4 0.2 0.21 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.9 GAO88805.1 - 0.027 13.4 0.2 0.088 11.7 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_18 PF13238.1 GAO88805.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 GAO88805.1 - 0.048 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 GAO88805.1 - 0.054 13.1 0.0 0.65 9.6 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase Prefoldin PF02996.12 GAO88807.1 - 5.2e-22 77.7 0.2 7.2e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 GAO88807.1 - 0.0015 18.2 0.8 0.045 13.5 0.2 2.0 2 0 0 2 2 2 1 Prefoldin subunit Scaffolding_pro PF11418.3 GAO88807.1 - 0.021 15.1 0.1 0.27 11.5 0.0 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein CBF PF03914.12 GAO88808.1 - 7.4e-47 158.8 0.1 7.4e-47 158.8 0.0 3.2 3 0 0 3 3 3 1 CBF/Mak21 family Aa_trans PF01490.13 GAO88809.1 - 3.8e-25 88.2 32.7 4.5e-25 87.9 22.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 GAO88810.1 - 9.5e-59 198.2 0.0 1.3e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAO88810.1 - 5.6e-19 67.9 0.1 1.2e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Glyco_hydro_92 PF07971.7 GAO88811.1 - 1.8e-167 558.0 0.1 2.2e-167 557.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 V-ATPase_C PF03223.10 GAO88812.1 - 4.2e-119 397.7 0.0 5.2e-119 397.4 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 GAO88812.1 - 3.2e-10 39.9 0.0 6.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily HHH_4 PF14490.1 GAO88812.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain APS_kinase PF01583.15 GAO88813.1 - 1.1e-70 236.3 0.0 1.3e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 GAO88813.1 - 3.8e-07 30.0 0.0 6.8e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO88813.1 - 2.4e-05 25.1 0.1 3.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO88813.1 - 3.2e-05 24.2 0.0 5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAO88813.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 GAO88813.1 - 0.0018 18.3 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 GAO88813.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAO88813.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ligase_CoA PF00549.14 GAO88814.1 - 2.1e-36 124.8 0.2 8.2e-18 64.4 0.0 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 GAO88814.1 - 2.2e-17 63.3 0.1 5.3e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 GAO88814.1 - 3.4e-11 42.9 0.0 7.2e-10 38.5 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAO88814.1 - 0.00034 20.7 0.2 0.0072 16.4 0.1 2.4 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 GAO88814.1 - 0.00067 19.1 0.0 0.0063 15.9 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain Rad60-SLD PF11976.3 GAO88816.1 - 8.3e-21 73.4 0.3 1e-20 73.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAO88816.1 - 7.2e-08 31.7 0.1 8.6e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 GAO88816.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 GAO88817.1 - 1e-64 218.4 3.4 6.8e-54 182.7 0.2 2.4 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Daxx PF03344.10 GAO88817.1 - 0.035 12.6 7.9 0.05 12.0 5.5 1.2 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 GAO88817.1 - 0.51 8.3 5.7 0.91 7.5 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 GAO88817.1 - 0.89 8.7 10.0 1.5 7.9 6.9 1.3 1 0 0 1 1 1 0 SDA1 HD PF01966.17 GAO88818.1 - 1.7e-05 24.7 0.0 3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 HD domain Pax2_C PF12403.3 GAO88818.1 - 0.016 14.8 1.1 0.029 14.0 0.8 1.3 1 0 0 1 1 1 0 Paired-box protein 2 C terminal E1-E2_ATPase PF00122.15 GAO88819.1 - 3.6e-59 199.5 2.8 7.2e-59 198.6 2.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO88819.1 - 1.5e-46 158.2 8.3 1.5e-46 158.2 5.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO88819.1 - 7.7e-26 91.8 0.0 4.5e-25 89.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO88819.1 - 1.2e-19 70.0 0.0 2.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO88819.1 - 1.8e-13 51.1 0.0 4.2e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO88819.1 - 1.2e-08 34.3 0.4 6e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAO88819.1 - 0.00025 20.7 1.5 0.002 17.7 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.10 GAO88820.1 - 5.3e-14 51.6 32.8 1.2e-13 50.5 22.7 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.4 GAO88821.1 - 1.6e-13 50.5 0.1 4.9e-13 48.9 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Tubulin PF00091.20 GAO88822.1 - 1.5e-69 234.1 0.0 2.5e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAO88822.1 - 1.4e-49 167.3 0.1 2.2e-49 166.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAO88822.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAO88822.1 - 0.007 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 GAO88823.1 - 2.2e-16 59.2 0.1 1.1e-06 28.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO88823.1 - 3.6e-10 39.6 0.1 0.0004 20.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88823.1 - 7.9e-10 38.4 0.0 1.5e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 GAO88824.1 - 3.3e-120 401.2 29.3 3.8e-120 401.0 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 GAO88825.1 - 1.7e-66 224.0 0.0 2.9e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88825.1 - 1.2e-36 126.1 0.0 3.2e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO88825.1 - 6e-08 31.9 0.1 2.9e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAO88825.1 - 0.003 17.3 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAO88825.1 - 0.018 13.8 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Vac_ImportDeg PF09783.4 GAO88826.1 - 5.9e-71 237.5 1.9 7.8e-71 237.2 1.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 GAO88827.1 - 8.9e-48 161.6 0.5 1e-47 161.4 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 GAO88828.1 - 4.2e-98 328.9 7.2 6.5e-98 328.3 5.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 GAO88828.1 - 4.4e-62 207.5 0.0 1.5e-61 205.8 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 GAO88828.1 - 6.1e-62 207.4 0.3 1.3e-61 206.3 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 GAO88828.1 - 1.1e-13 51.3 5.2 1.5e-07 31.5 0.0 4.5 2 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 GAO88828.1 - 6.6e-06 26.0 7.8 0.0031 17.3 0.0 3.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAO88828.1 - 7e-05 22.5 0.2 0.17 12.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 GAO88828.1 - 0.00028 21.2 1.7 0.053 14.0 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.18 GAO88828.1 - 0.055 13.3 0.1 3.5 7.6 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.19 GAO88829.1 - 6.8e-25 86.9 0.1 1.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 GAO88830.1 - 1.1e-43 149.2 0.2 2.7e-36 125.0 0.6 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 NOT2_3_5 PF04153.13 GAO88830.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DUF1604 PF07713.8 GAO88832.1 - 8.7e-40 134.4 1.9 8.7e-40 134.4 1.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 GAO88832.1 - 9.8e-07 28.4 2.4 4.3e-06 26.4 1.7 2.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAO88832.1 - 0.012 15.4 2.2 0.012 15.4 1.5 3.0 4 0 0 4 4 4 0 DExH-box splicing factor binding site Pkinase PF00069.20 GAO88833.1 - 1.3e-77 260.4 0.0 2.3e-77 259.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88833.1 - 4.9e-41 140.5 0.0 1e-40 139.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SET PF00856.23 GAO88833.1 - 3.1e-21 76.3 4.1 4.8e-21 75.7 0.0 3.6 5 1 0 5 5 5 1 SET domain Pre-SET PF05033.11 GAO88833.1 - 1.1e-15 57.7 2.3 3.2e-15 56.2 1.6 1.7 1 0 0 1 1 1 1 Pre-SET motif KA1 PF02149.14 GAO88833.1 - 1.8e-08 33.6 0.2 3.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 GAO88833.1 - 7.7e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAO88833.1 - 5.8e-05 22.2 0.0 0.00099 18.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAO88833.1 - 0.0033 17.2 0.0 0.024 14.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAO88833.1 - 0.0035 16.7 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 GAO88833.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF740 PF05340.7 GAO88834.1 - 6.3 5.0 7.7 7.3 4.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Ion_trans PF00520.26 GAO88836.1 - 8.9e-103 341.7 80.3 7.4e-36 123.2 2.1 5.3 5 0 0 5 5 5 5 Ion transport protein EF-hand_1 PF00036.27 GAO88836.1 - 0.0011 18.0 0.0 0.0028 16.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAO88836.1 - 0.0075 16.0 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 GAO88836.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Proteasom_Rpn13 PF04683.8 GAO88837.1 - 5.6e-28 96.8 0.0 8.3e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 GAO88837.1 - 0.065 12.7 0.4 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 L27_2 Ribosomal_L6e PF01159.14 GAO88838.1 - 4.4e-38 129.8 0.9 6.6e-38 129.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF1070 PF06376.7 GAO88838.1 - 0.25 11.2 2.2 0.35 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1070) FA_hydroxylase PF04116.8 GAO88839.1 - 5.4e-14 52.5 7.3 5.4e-14 52.5 5.0 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 GAO88840.1 - 1.3e-20 73.9 0.1 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO88840.1 - 1.2e-10 41.3 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO88840.1 - 3.8e-08 33.3 0.0 6.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO88840.1 - 4.8e-06 26.1 0.1 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO88840.1 - 0.0011 19.0 0.8 0.0034 17.4 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 GAO88840.1 - 0.0039 17.3 0.1 0.0075 16.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAO88840.1 - 0.0053 16.4 0.4 0.0098 15.5 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 GAO88840.1 - 0.0066 15.5 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 GAO88840.1 - 0.02 15.3 1.6 0.026 14.9 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 GAO88840.1 - 0.037 14.2 0.2 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 GAO88840.1 - 0.056 12.3 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.11 GAO88840.1 - 0.062 12.7 0.1 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sas10 PF09368.5 GAO88841.1 - 7.3e-29 99.7 6.5 7.3e-29 99.7 4.5 3.3 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 GAO88841.1 - 3.6e-16 59.1 2.7 2.1e-15 56.6 0.0 3.4 2 1 1 3 3 3 1 Sas10/Utp3/C1D family MutS_V PF00488.16 GAO88842.1 - 1.4e-54 184.9 0.0 2.5e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO88842.1 - 1.2e-19 70.9 0.0 2.7e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 MutS domain III AAA PF00004.24 GAO88842.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MutS_IV PF05190.13 GAO88842.1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 GAO88842.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAO88842.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAO88843.1 - 9.1e-46 155.8 0.0 2.3e-43 148.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 GAO88843.1 - 1.4e-25 89.0 0.3 5e-25 87.2 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 GAO88843.1 - 6.6e-19 68.4 0.0 3.3e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAO88843.1 - 4.1e-14 52.4 0.1 1.4e-09 37.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO88843.1 - 2.8e-11 43.7 12.8 0.00018 21.5 0.0 5.8 4 2 2 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 GAO88843.1 - 1.3e-09 38.2 1.3 0.0046 17.1 0.0 3.7 2 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 GAO88843.1 - 3.2e-07 29.9 0.6 0.00033 20.1 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 GAO88843.1 - 8.7e-07 28.8 0.0 0.038 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAO88843.1 - 4e-06 26.5 0.1 0.066 12.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 GAO88843.1 - 2.1e-05 24.3 5.5 0.088 12.4 0.1 4.6 3 2 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 GAO88843.1 - 4.4e-05 24.2 5.3 0.13 13.0 0.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_28 PF13521.1 GAO88843.1 - 6.6e-05 22.9 0.9 0.059 13.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAO88843.1 - 9.1e-05 22.7 4.6 0.12 12.6 0.0 3.4 4 0 0 4 4 2 2 AAA domain IstB_IS21 PF01695.12 GAO88843.1 - 0.0001 21.7 0.0 0.42 9.9 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein MobB PF03205.9 GAO88843.1 - 0.00021 20.9 0.0 0.077 12.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAO88843.1 - 0.00021 20.9 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain TrwB_AAD_bind PF10412.4 GAO88843.1 - 0.00044 18.9 0.1 0.051 12.1 0.0 2.7 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 GAO88843.1 - 0.0019 17.4 0.1 0.72 8.9 0.0 3.2 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAO88843.1 - 0.0021 18.1 0.0 1.1 9.5 0.0 2.8 2 1 0 2 2 2 1 RNA helicase SRP54 PF00448.17 GAO88843.1 - 0.0025 17.3 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF853 PF05872.7 GAO88843.1 - 0.004 15.5 0.1 0.031 12.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.2 GAO88843.1 - 0.0072 15.7 0.1 0.3 10.4 0.0 3.2 2 2 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 GAO88843.1 - 0.0079 16.5 1.8 2.2 8.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 GAO88843.1 - 0.0083 15.5 0.7 1.6 8.0 0.1 3.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.1 GAO88843.1 - 0.0094 15.8 0.0 2.1 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 GAO88843.1 - 0.0099 15.3 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 GAO88843.1 - 0.012 14.7 0.0 0.56 9.2 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 GAO88843.1 - 0.015 14.8 0.0 0.53 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.1 GAO88843.1 - 0.016 14.8 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF258 PF03193.11 GAO88843.1 - 0.017 14.3 0.0 5.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 GAO88843.1 - 0.02 14.4 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 GAO88843.1 - 0.021 14.3 7.2 0.16 11.5 0.0 4.3 3 1 1 5 5 4 0 AAA domain UPF0079 PF02367.12 GAO88843.1 - 0.025 14.2 0.1 12 5.5 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 GAO88843.1 - 0.032 13.1 0.3 0.54 9.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ResIII PF04851.10 GAO88843.1 - 0.043 13.6 5.0 3.6 7.3 0.0 3.5 3 2 1 4 4 3 0 Type III restriction enzyme, res subunit Miro PF08477.8 GAO88843.1 - 0.049 14.1 1.7 1.5 9.3 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein GAS PF13851.1 GAO88843.1 - 0.061 12.5 11.4 0.14 11.3 7.9 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_23 PF13476.1 GAO88843.1 - 0.097 12.9 10.1 1.1 9.5 2.3 3.5 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 GAO88843.1 - 0.098 12.1 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 GAO88843.1 - 0.13 11.5 5.0 0.52 9.5 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF948 PF06103.6 GAO88843.1 - 0.2 11.5 2.4 10 6.0 0.5 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 GAO88843.1 - 0.41 8.4 4.1 0.58 7.9 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 GAO88843.1 - 0.45 10.2 4.8 25 4.6 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function DUF87 Atg14 PF10186.4 GAO88843.1 - 1.7 7.5 10.8 3 6.7 7.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliL PF03748.9 GAO88843.1 - 1.9 8.5 6.1 13 5.8 4.2 2.4 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL APG6 PF04111.7 GAO88843.1 - 4.5 6.2 10.1 7.7 5.4 7.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 GAO88843.1 - 4.7 6.7 15.5 4.2 6.9 6.2 2.9 2 1 1 3 3 2 0 Septum formation initiator DUF2968 PF11180.3 GAO88843.1 - 5.4 6.3 14.0 11 5.4 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) EF1_GNE PF00736.14 GAO88844.1 - 2e-32 110.7 3.6 3.5e-32 109.9 2.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 GAO88844.1 - 8e-11 41.8 3.2 8e-11 41.8 2.2 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 GAO88844.1 - 7.2e-06 25.8 0.0 2.4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO88844.1 - 1.5e-05 24.7 0.4 0.0015 18.3 0.3 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO88844.1 - 6.6e-05 23.3 0.0 0.00026 21.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 GAO88844.1 - 0.16 11.5 3.8 0.041 13.4 0.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein MMgT PF10270.4 GAO88845.1 - 3.6e-36 123.8 0.0 4.1e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter Flavi_NS2B PF01002.14 GAO88845.1 - 0.046 13.3 0.1 0.065 12.8 0.1 1.4 1 1 0 1 1 1 0 Flavivirus non-structural protein NS2B K_trans PF02705.11 GAO88846.1 - 2.8e-182 606.8 20.0 2.8e-97 326.3 6.6 2.0 2 0 0 2 2 2 2 K+ potassium transporter Syndecan PF01034.15 GAO88846.1 - 9.3 5.9 6.8 3.2 7.4 0.3 3.1 3 0 0 3 3 3 0 Syndecan domain CDC27 PF09507.5 GAO88847.1 - 0.98 8.5 12.6 1.2 8.2 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GST_C PF00043.20 GAO88848.1 - 1.4e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO88848.1 - 0.00016 21.5 0.3 0.00035 20.3 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO88848.1 - 0.0068 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO88848.1 - 0.023 15.1 0.1 0.07 13.6 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HMG-CoA_red PF00368.13 GAO88849.1 - 2.8e-154 513.3 8.3 3.5e-154 512.9 5.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 GAO88849.1 - 1.2e-22 80.2 0.4 2.7e-22 79.0 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 GAO88849.1 - 3.1e-14 52.7 2.7 3.1e-14 52.7 1.9 2.2 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAO88849.1 - 6.5 4.5 11.6 0.26 9.1 4.1 1.5 2 0 0 2 2 2 0 Patched family Metal_resist PF13801.1 GAO88850.1 - 0.029 14.3 3.7 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance MACPF PF01823.14 GAO88852.1 - 5.3e-07 29.5 0.3 9.5e-06 25.4 0.0 2.6 3 0 0 3 3 3 1 MAC/Perforin domain Tho2 PF11262.3 GAO88852.1 - 0.057 12.4 1.1 0.11 11.5 0.8 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ribonuclease PF00545.15 GAO88853.1 - 1.8e-11 43.9 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 ribonuclease MBOAT_2 PF13813.1 GAO88854.1 - 2.1e-22 79.0 2.9 7e-22 77.3 2.0 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ECF-ribofla_trS PF07155.7 GAO88854.1 - 0.00079 19.1 0.8 0.0016 18.1 0.5 1.5 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component Peptidase_S24 PF00717.18 GAO88855.1 - 3.3e-06 26.6 0.0 5e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like Tub_2 PF04525.7 GAO88857.1 - 5.9e-13 48.6 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 Peptidase_M20 PF01546.23 GAO88859.1 - 3.6e-20 72.2 0.1 5.6e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO88859.1 - 4.2e-13 49.0 0.0 1.9e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain HNH_2 PF13391.1 GAO88860.1 - 0.14 11.9 0.1 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease p450 PF00067.17 GAO88862.1 - 3.1e-44 151.2 0.0 4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.21 GAO88863.1 - 1.7e-35 121.4 0.0 2.8e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO88863.1 - 0.0041 16.8 0.1 0.0099 15.6 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 GAO88863.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 RWD domain RNB PF00773.14 GAO88864.1 - 3.3e-84 282.9 0.5 1.3e-82 277.7 0.1 2.3 2 0 0 2 2 2 2 RNB domain GLE1 PF07817.8 GAO88865.1 - 1.5e-12 46.9 0.0 1.5e-12 46.9 0.0 2.7 2 2 0 3 3 3 1 GLE1-like protein DUF2413 PF10310.4 GAO88865.1 - 2 7.1 30.0 2.7 6.7 20.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Glyco_hydro_17 PF00332.13 GAO88866.1 - 3.7e-23 82.0 0.1 9.6e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 GAS PF13851.1 GAO88866.1 - 0.0022 17.2 22.7 0.0022 17.2 15.8 5.3 2 1 3 5 5 5 2 Growth-arrest specific micro-tubule binding Myb_DNA-bind_3 PF12776.2 GAO88867.1 - 0.03 14.9 0.1 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DNA_PPF PF02916.10 GAO88867.1 - 0.071 13.1 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase processivity factor EMP24_GP25L PF01105.19 GAO88868.1 - 5.1e-47 159.9 0.4 5.9e-47 159.7 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3237 PF11578.3 GAO88869.1 - 4e-61 204.7 0.2 4.5e-61 204.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Phage_Coat_A PF05357.8 GAO88869.1 - 0.056 13.0 0.5 0.46 10.1 0.0 2.4 2 1 0 2 2 2 0 Phage Coat Protein A Metallophos PF00149.23 GAO88870.1 - 1.4e-07 31.0 0.7 5.1e-07 29.2 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 14-3-3 PF00244.15 GAO88871.1 - 2.3e-11 43.2 0.0 5.3e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 14-3-3 protein Fungal_trans PF04082.13 GAO88872.1 - 2e-14 53.1 0.1 3.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.9 GAO88873.1 - 1.5e-34 118.8 0.1 1.8e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 GAO88873.1 - 0.0018 17.1 0.1 0.0041 15.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) DLH PF01738.13 GAO88873.1 - 0.047 12.9 0.2 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family PEP_mutase PF13714.1 GAO88873.1 - 0.066 12.4 0.8 2.2 7.4 0.0 3.0 3 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase DUF836 PF05768.9 GAO88874.1 - 4.3e-14 52.5 0.0 5.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 GAO88874.1 - 0.004 17.1 0.1 0.0075 16.2 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 GAO88874.1 - 0.074 13.2 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain CHORD PF04968.7 GAO88875.1 - 1.8e-52 175.4 18.1 3.7e-27 94.3 3.7 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 GAO88875.1 - 4.1e-15 56.0 0.3 6.3e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 CS domain Choline_kinase PF01633.15 GAO88876.1 - 8.5e-46 156.1 0.0 1.8e-44 151.8 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAO88876.1 - 8.5e-12 45.3 0.8 2.2e-11 43.9 0.4 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family AP_endonuc_2 PF01261.19 GAO88877.1 - 8.2e-25 87.3 0.0 1.8e-24 86.2 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.17 GAO88878.1 - 7.4e-29 100.7 0.1 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO88878.1 - 1.2e-16 60.5 0.0 2.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 GAO88878.1 - 0.00016 21.9 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAO88878.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 GAO88878.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 GAO88879.1 - 2e-131 438.6 28.0 2.3e-131 438.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88879.1 - 1.1e-25 90.1 37.0 1.1e-25 90.1 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 GAO88880.1 - 2.4e-21 75.5 0.0 6e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO88880.1 - 6.2e-12 45.7 0.0 9.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.20 GAO88881.1 - 7e-75 251.8 0.1 8.6e-73 244.9 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 GAO88882.1 - 2.4e-63 211.6 0.1 2.7e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Fungal_trans PF04082.13 GAO88883.1 - 4.2e-23 81.5 0.0 1e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO88883.1 - 1.7e-06 27.8 15.9 1.7e-06 27.8 11.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 GAO88884.1 - 5.1e-58 196.3 0.0 7.4e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 GAO88884.1 - 2.5e-22 78.7 0.0 6.7e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 GAO88884.1 - 2.4e-21 76.2 0.0 5.1e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 GAO88884.1 - 3e-11 43.5 0.1 6.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAO88884.1 - 0.00058 20.2 0.1 0.075 13.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AAA_17 PF13207.1 GAO88884.1 - 0.001 19.8 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAO88884.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO88884.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF947 PF06102.7 GAO88884.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF947) AAA_28 PF13521.1 GAO88884.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAO88884.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TF_AP-2 PF03299.9 GAO88884.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 Sod_Cu PF00080.15 GAO88885.1 - 4.2e-16 59.3 0.0 5.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pyr_redox_3 PF13738.1 GAO88886.1 - 7e-27 94.8 0.1 1.7e-26 93.5 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO88886.1 - 1.1e-23 83.2 0.0 6e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAO88886.1 - 1.2e-12 48.1 0.0 2.4e-09 37.3 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO88886.1 - 4e-12 45.7 0.0 4.9e-10 38.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 GAO88886.1 - 1.8e-08 33.7 0.0 0.0023 17.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAO88886.1 - 5e-08 33.2 0.1 0.0035 17.7 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO88886.1 - 8.8e-08 31.5 1.1 0.00051 19.1 0.1 3.0 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 GAO88886.1 - 1.6e-06 28.0 0.0 5.8e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAO88886.1 - 3.7e-06 26.6 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAO88886.1 - 5.6e-06 26.4 0.0 0.068 13.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 GAO88886.1 - 1.2e-05 24.7 0.0 7.6e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 GAO88886.1 - 5.2e-05 23.4 0.0 0.0067 16.6 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.12 GAO88886.1 - 0.0002 21.7 0.0 0.78 10.2 0.0 3.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 GAO88886.1 - 0.00036 20.5 0.3 0.5 10.3 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain GIDA PF01134.17 GAO88886.1 - 0.001 17.9 0.3 3.3 6.4 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAO88886.1 - 0.0014 17.5 0.3 0.18 10.6 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAO88886.1 - 0.0019 17.7 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 GAO88886.1 - 0.0021 17.6 0.1 0.011 15.3 0.3 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_9 PF13454.1 GAO88886.1 - 0.0023 17.7 0.1 1.6 8.5 0.0 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_2 PF03446.10 GAO88886.1 - 0.0024 17.7 0.1 0.26 11.1 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 GAO88886.1 - 0.0041 15.6 0.0 0.18 10.2 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.11 GAO88886.1 - 0.0047 16.3 0.0 0.53 9.7 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 GAO88886.1 - 0.0078 15.1 0.7 0.073 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAO88886.1 - 0.0093 15.0 0.0 6 5.8 0.0 2.9 3 0 0 3 3 3 0 Thi4 family DAO PF01266.19 GAO88886.1 - 0.013 14.4 2.1 0.33 9.8 0.0 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 GAO88886.1 - 0.022 14.7 0.1 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding ANTAR PF03861.9 GAO88886.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain UDPG_MGDP_dh_N PF03721.9 GAO88886.1 - 0.05 12.9 0.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 GAO88886.1 - 0.072 12.9 0.1 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO88886.1 - 0.073 12.7 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.14 GAO88886.1 - 0.091 11.8 0.3 0.42 9.6 0.0 2.1 3 0 0 3 3 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3405 PF11885.3 GAO88887.1 - 1.1e-226 752.8 0.2 1.3e-226 752.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LSM PF01423.17 GAO88888.1 - 3.5e-16 58.4 0.0 5.7e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain WH2 PF02205.15 GAO88889.1 - 7.8e-11 41.2 0.7 1.8e-10 40.0 0.5 1.7 1 0 0 1 1 1 1 WH2 motif HisKA_2 PF07568.7 GAO88890.1 - 0.14 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase Ribosomal_L1 PF00687.16 GAO88891.1 - 9.3e-54 182.0 1.0 1.1e-53 181.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 GAO88891.1 - 0.021 13.3 0.1 0.03 12.7 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Fungal_trans PF04082.13 GAO88892.1 - 2.7e-15 55.9 0.0 4.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 GAO88893.1 - 1.3e-06 27.6 3.9 0.0023 17.0 0.3 2.7 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein Arf PF00025.16 GAO88894.1 - 2.2e-79 264.7 0.1 2.6e-79 264.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAO88894.1 - 5.1e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAO88894.1 - 2.9e-13 49.5 0.0 3.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAO88894.1 - 3.7e-12 45.6 1.5 2.2e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAO88894.1 - 5.8e-11 41.9 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO88894.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAO88894.1 - 2.9e-06 27.2 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO88894.1 - 0.011 15.2 0.1 0.074 12.4 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 GAO88894.1 - 0.012 14.7 0.3 0.02 14.0 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 GAO88894.1 - 0.042 13.7 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain HWE_HK PF07536.9 GAO88895.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase SURF4 PF02077.10 GAO88897.1 - 2.2e-92 309.2 7.3 2.5e-92 309.0 5.1 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 GAO88897.1 - 0.0035 17.7 14.5 0.014 15.7 0.9 3.2 3 1 0 3 3 3 2 DoxX TP53IP5 PF15331.1 GAO88898.1 - 0.0038 17.1 13.8 0.0038 17.1 9.6 2.7 3 1 0 3 3 3 1 Cellular tumour antigen p53-inducible 5 PA26 PF04636.8 GAO88898.1 - 8.3 4.9 15.0 1.5 7.3 0.5 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) IU_nuc_hydro PF01156.14 GAO88899.1 - 8.6e-59 199.2 0.0 1.7e-57 195.0 0.0 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HLH PF00010.21 GAO88900.1 - 3.7e-15 55.3 0.3 1.9e-14 53.1 0.3 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Baculo_VP91_N PF08475.5 GAO88901.1 - 0.031 13.6 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Pyr_redox_3 PF13738.1 GAO88902.1 - 2.7e-13 50.4 0.0 5.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO88902.1 - 2.6e-11 42.4 0.0 8.5e-11 40.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAO88902.1 - 8e-08 32.3 0.0 4.3e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO88902.1 - 6.7e-06 26.0 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO88902.1 - 3.6e-05 23.5 0.1 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO88902.1 - 0.00064 20.0 0.1 0.3 11.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO88902.1 - 0.0036 16.2 0.0 0.24 10.2 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAO88902.1 - 0.01 14.9 0.7 0.11 11.5 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.12 GAO88902.1 - 0.04 12.9 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 GAO88902.1 - 0.24 9.8 0.0 0.45 8.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 GAO88903.1 - 1.3e-31 109.6 24.8 1.3e-31 109.6 17.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF543 PF04418.7 GAO88903.1 - 0.058 13.3 1.1 0.15 12.0 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Sugar_tr PF00083.19 GAO88904.1 - 2.3e-96 323.1 22.1 2.7e-96 322.9 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO88904.1 - 9.9e-33 113.2 44.0 2.3e-27 95.6 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO88904.1 - 1.8e-05 23.3 21.7 0.0025 16.2 3.3 3.6 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4211 PF13926.1 GAO88906.1 - 1.5e-45 154.3 0.0 4.4e-45 152.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF2183 PF09949.4 GAO88906.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Tom22 PF04281.8 GAO88907.1 - 2.1e-54 182.7 2.2 2.4e-54 182.5 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YL1 PF05764.8 GAO88907.1 - 0.2 11.2 3.9 0.3 10.6 2.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_M16_C PF05193.16 GAO88908.1 - 2.1e-50 170.9 0.0 8.3e-50 169.0 0.0 2.0 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAO88908.1 - 8.5e-42 142.4 0.0 3.8e-40 137.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.6 GAO88908.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Disulphide isomerase Transferase PF02458.10 GAO88909.1 - 1.6e-24 86.1 0.0 1.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family AMP-binding PF00501.23 GAO88910.1 - 2e-42 145.0 0.0 2.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO88910.1 - 0.00012 22.9 0.0 0.00027 21.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 GAO88911.1 - 1.1e-64 218.6 0.0 1.4e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAO88911.1 - 0.0027 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Tmemb_18A PF09771.4 GAO88911.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Aminotran_5 PF00266.14 GAO88911.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V PQ-loop PF04193.9 GAO88912.1 - 9.1e-34 114.8 17.5 7.2e-19 67.1 0.2 3.1 3 0 0 3 3 3 2 PQ loop repeat V_ATPase_I PF01496.14 GAO88912.1 - 0.0019 16.1 0.0 0.0026 15.7 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MtN3_slv PF03083.11 GAO88912.1 - 0.73 9.7 3.8 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SH3_1 PF00018.23 GAO88914.1 - 7.4e-05 22.0 0.0 0.00016 21.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO88914.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.20 GAO88915.1 - 5.2e-51 173.2 0.0 7e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO88915.1 - 2.7e-26 92.1 0.0 1.6e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase VirE3 PF06661.6 GAO88915.1 - 0.08 12.0 0.3 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 VirE3 Ribosomal_L18e PF00828.14 GAO88916.1 - 3.8e-16 59.6 0.2 7.4e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Cyclin PF08613.6 GAO88917.1 - 1.8e-16 60.8 0.0 2.9e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAO88917.1 - 0.00056 19.4 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 GAO88918.1 - 6.6e-27 94.6 0.1 1.5e-15 57.6 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO88918.1 - 1.3e-12 47.9 0.0 6e-11 42.5 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO88918.1 - 0.0015 18.6 0.9 1.6 8.7 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF964 PF06133.6 GAO88918.1 - 0.0048 16.8 2.7 0.013 15.4 1.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF964) NAD_binding_7 PF13241.1 GAO88918.1 - 1.7 8.9 5.4 9.1 6.6 0.0 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding Dynamin_N PF00350.18 GAO88919.1 - 3.2e-44 150.6 0.0 5.9e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAO88919.1 - 7.3e-11 41.3 0.2 4.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 GAO88919.1 - 0.0016 18.4 0.0 0.0045 16.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO88919.1 - 0.003 18.0 0.0 0.0068 16.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Zeta_toxin PF06414.7 GAO88919.1 - 0.029 13.4 0.3 11 5.1 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin DUF2939 PF11159.3 GAO88919.1 - 0.063 13.4 0.1 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) PduV-EutP PF10662.4 GAO88919.1 - 0.15 11.5 0.0 23 4.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 GAO88919.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 GAO88920.1 - 1.1e-14 53.8 0.0 1.6e-13 49.9 0.0 2.1 1 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAO88920.1 - 1.3e-09 38.0 0.0 2.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAO88920.1 - 1.4e-06 27.2 0.1 0.00036 19.3 0.2 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II RRM_1 PF00076.17 GAO88922.1 - 7e-60 198.5 0.0 3.9e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO88922.1 - 2.2e-43 146.0 0.0 9e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88922.1 - 1.7e-28 98.1 0.0 3.3e-10 39.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO88922.1 - 8.9e-05 22.1 0.1 0.13 12.0 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 GAO88922.1 - 0.004 17.0 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Arrestin_C PF02752.17 GAO88924.1 - 4.7e-23 81.8 0.0 1.9e-21 76.6 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAO88924.1 - 1.3e-08 34.7 0.1 0.00012 21.9 0.0 2.9 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain ABM PF03992.11 GAO88925.1 - 1.9e-08 34.2 0.1 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.8 GAO88925.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.3 1 1 0 1 1 1 0 NIPSNAP zf-DBF PF07535.7 GAO88925.1 - 0.08 12.6 0.7 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 DBF zinc finger Toprim PF01751.17 GAO88925.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 Toprim domain Abhydrolase_5 PF12695.2 GAO88926.1 - 1.6e-06 27.9 0.0 4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO88926.1 - 0.00014 21.5 0.2 0.00027 20.5 0.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAO88926.1 - 0.00024 20.4 0.0 0.00044 19.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAO88926.1 - 0.00032 20.6 2.0 0.00064 19.6 1.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 GAO88926.1 - 0.031 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.15 GAO88926.1 - 0.05 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF915 PF06028.6 GAO88926.1 - 0.079 12.0 0.0 13 4.7 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Chs3p PF12271.3 GAO88927.1 - 2.5e-142 473.1 17.6 2.8e-142 472.9 12.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 GAO88927.1 - 7.7 6.4 8.9 0.37 10.7 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Acetyltransf_1 PF00583.19 GAO88928.1 - 8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAO88928.1 - 9.9e-09 35.1 0.2 2.2e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO88928.1 - 3.9e-08 33.3 0.0 7.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO88928.1 - 3.8e-06 26.9 0.0 8.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO88928.1 - 7e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAO88928.1 - 0.00044 19.9 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein 4HBT_3 PF13622.1 GAO88929.1 - 1.5e-50 172.3 0.2 1.8e-50 172.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAO88929.1 - 0.00021 20.9 0.0 0.75 9.4 0.0 3.0 2 1 1 3 3 3 2 Acyl-CoA thioesterase AfsA PF03756.8 GAO88929.1 - 0.0098 15.6 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 A-factor biosynthesis hotdog domain Ribosomal_S6 PF01250.12 GAO88930.1 - 2e-08 33.9 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 MerR_1 PF13411.1 GAO88930.1 - 0.096 12.4 0.1 0.57 9.9 0.0 2.1 2 1 0 2 2 2 0 MerR HTH family regulatory protein GCV_H PF01597.14 GAO88931.1 - 4.2e-37 126.5 2.2 5.4e-37 126.1 1.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF3966 PF13110.1 GAO88931.1 - 0.1 12.4 0.9 0.25 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) Biotin_lipoyl PF00364.17 GAO88931.1 - 0.13 11.8 0.7 0.28 10.8 0.2 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme zf-rbx1 PF12678.2 GAO88932.1 - 9.8e-10 38.4 0.3 1.8e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAO88932.1 - 3.4e-09 36.3 10.7 6.3e-08 32.3 7.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAO88932.1 - 1.7e-07 30.7 0.8 3e-07 29.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO88932.1 - 3.9e-07 29.6 2.5 1.2e-06 28.1 1.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAO88932.1 - 1.7e-06 27.5 5.7 9.1e-06 25.2 4.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAO88932.1 - 2.8e-05 24.0 2.8 2.8e-05 24.0 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAO88932.1 - 0.0082 15.9 1.2 0.019 14.7 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 GAO88932.1 - 0.21 9.2 0.2 0.31 8.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 GAO88932.1 - 0.45 10.2 4.3 0.36 10.5 0.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 GAO88932.1 - 2.3 8.2 5.9 10 6.1 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 GAO88932.1 - 5.3 7.1 5.4 1.9 8.5 1.3 1.9 2 0 0 2 2 2 0 RING-variant domain Cation_efflux PF01545.16 GAO88933.1 - 4.5e-33 114.5 10.0 5.7e-33 114.2 6.9 1.1 1 0 0 1 1 1 1 Cation efflux family LcrV PF04792.7 GAO88934.1 - 0.089 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein COMPASS-Shg1 PF05205.7 GAO88936.1 - 2.8e-33 114.3 1.5 7.7e-33 112.9 0.3 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 MIP-T3 PF10243.4 GAO88936.1 - 1.8e-05 23.4 50.0 2.7e-05 22.8 34.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF4598 PF15370.1 GAO88937.1 - 7.5e-43 145.3 6.7 7.5e-43 145.3 4.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) GDA1_CD39 PF01150.12 GAO88938.1 - 8.8e-92 307.8 0.0 1.1e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MCE PF02470.15 GAO88938.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 mce related protein IF3_C PF00707.17 GAO88939.1 - 3.6e-19 68.3 1.7 6e-19 67.5 1.2 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 GAO88939.1 - 1.9e-06 27.3 3.2 2.1e-05 23.9 0.9 2.8 1 1 2 3 3 3 1 Mitochondrial translation initiation factor IF3_N PF05198.11 GAO88939.1 - 2.4e-05 24.1 0.1 5.8e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain ALO PF04030.9 GAO88939.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DUF1827 PF08860.5 GAO88939.1 - 0.019 15.0 0.2 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1599 PF07659.6 GAO88939.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1599) Glucan_synthase PF02364.10 GAO88939.1 - 0.11 10.4 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component GTP_EFTU PF00009.22 GAO88940.1 - 3.8e-60 202.5 0.1 5.1e-60 202.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAO88940.1 - 1.2e-22 79.9 0.0 9.8e-22 76.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAO88940.1 - 1.4e-17 63.5 1.0 3.1e-17 62.4 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO88940.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAO88940.1 - 0.00091 18.8 0.3 0.0025 17.4 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 GAO88940.1 - 0.0012 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 GAO88940.1 - 0.084 12.3 0.2 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 GAO88940.1 - 0.19 11.1 0.7 0.78 9.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RHD3 PF05879.7 GAO88941.1 - 0 1113.8 0.0 0 1113.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 GAO88941.1 - 1.1e-07 31.1 0.1 2e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 GAO88941.1 - 3.4e-06 26.9 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAO88941.1 - 0.00043 20.2 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 GAO88941.1 - 0.0052 16.7 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAO88941.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Cyclase PF04199.8 GAO88942.1 - 1.1e-06 28.5 0.2 2.4e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 GAO88942.1 - 0.0029 16.9 0.0 0.0058 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 4HBT_2 PF13279.1 GAO88943.1 - 1.6e-11 44.7 0.0 2.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Oxidored_FMN PF00724.15 GAO88944.1 - 8.7e-43 146.6 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.2 GAO88945.1 - 7.9e-45 151.1 0.0 2.3e-16 59.8 0.0 5.4 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO88945.1 - 1.3e-40 135.1 0.3 5.2e-07 29.1 0.0 9.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 GAO88945.1 - 2.9e-34 116.8 2.0 4.8e-10 39.6 0.0 7.1 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO88945.1 - 1.2e-31 107.9 1.8 1.1e-11 44.5 0.0 7.1 7 1 2 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88945.1 - 1.2e-26 90.0 0.3 0.00081 19.4 0.0 9.0 10 0 0 10 10 10 5 Ankyrin repeat CorA PF01544.13 GAO88945.1 - 2.5e-07 30.0 3.1 8.6e-07 28.2 2.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3417 PF11897.3 GAO88945.1 - 0.37 10.7 4.7 0.42 10.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) PTR2 PF00854.16 GAO88946.1 - 2.8e-43 148.1 20.6 1.3e-23 83.4 5.9 2.4 3 0 0 3 3 3 2 POT family MFS_1 PF07690.11 GAO88946.1 - 1.7e-05 23.7 26.1 0.00012 20.9 16.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily HIG_1_N PF04588.8 GAO88947.1 - 3.1e-10 39.6 0.6 5.7e-10 38.7 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Romo1 PF10247.4 GAO88947.1 - 1.2 9.3 5.0 0.58 10.3 1.4 1.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Med26 PF08711.6 GAO88948.1 - 8.3e-13 47.6 0.0 1.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.4 GAO88949.1 - 5.4e-19 67.5 1.5 4e-13 48.7 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 GAO88950.1 - 1.4e-44 151.2 0.4 1.4e-44 151.2 0.3 2.4 2 1 2 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 GAO88950.1 - 8.1e-21 74.3 179.0 1.3e-10 41.5 30.2 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region Fib_alpha PF08702.5 GAO88950.1 - 0.035 14.2 0.6 0.12 12.5 0.4 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 GAO88950.1 - 0.27 10.8 5.1 0.62 9.6 3.5 1.7 1 0 0 1 1 1 0 Mnd1 family CHCH PF06747.8 GAO88951.1 - 7.6e-08 32.0 5.8 7.6e-08 32.0 4.0 2.6 3 0 0 3 3 3 2 CHCH domain COX6B PF02297.12 GAO88951.1 - 0.22 11.5 7.8 0.61 10.1 1.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 GAO88951.1 - 0.25 11.1 14.5 1.3 8.8 3.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CD45 PF12567.3 GAO88951.1 - 7.7 6.4 9.8 0.21 11.4 2.1 1.8 2 0 0 2 2 2 0 Leukocyte receptor CD45 AA_permease_2 PF13520.1 GAO88952.1 - 6.5e-55 186.3 59.2 8.6e-55 185.9 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO88952.1 - 2.1e-35 121.9 56.2 3.3e-35 121.3 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease ACBP PF00887.14 GAO88952.1 - 3.1e-27 94.0 0.0 5.4e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein eIF-3c_N PF05470.7 GAO88952.1 - 0.25 9.3 9.7 0.36 8.8 6.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.4 GAO88952.1 - 0.47 9.1 19.7 0.87 8.2 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 GAO88952.1 - 3.5 6.5 17.4 5.3 6.0 12.0 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 GAO88952.1 - 3.7 5.9 18.9 5.5 5.3 13.1 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 GAO88952.1 - 4.5 4.8 6.9 6.3 4.3 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 GAO88952.1 - 6.2 4.5 18.1 9.1 4.0 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAO88952.1 - 8.4 4.2 19.1 13 3.7 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein JmjC PF02373.17 GAO88953.1 - 1.3e-37 128.5 0.5 1.3e-37 128.5 0.4 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 GAO88953.1 - 2.7e-17 62.7 3.7 5.6e-17 61.7 2.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAO88953.1 - 2.8e-17 62.6 4.4 6.1e-17 61.5 3.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 GAO88953.1 - 6e-15 54.4 0.2 1.3e-14 53.3 0.2 1.7 1 0 0 1 1 1 1 jmjN domain Carn_acyltransf PF00755.15 GAO88954.1 - 9.3e-167 555.6 0.0 1.2e-151 505.7 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF1515 PF07439.6 GAO88954.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CAP PF00188.21 GAO88955.1 - 2.6e-18 66.7 2.6 4.8e-18 65.8 1.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.10 GAO88956.1 - 2e-71 239.0 0.0 3.8e-71 238.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 GAO88956.1 - 3.2e-07 30.2 0.0 7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Sigma70_r4 PF04545.11 GAO88956.1 - 0.022 14.0 0.2 0.071 12.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1680 PF07944.7 GAO88956.1 - 0.084 11.1 0.1 6.7 4.8 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Thioredoxin_2 PF13098.1 GAO88956.1 - 0.11 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.27 GAO88957.1 - 9.8e-32 107.6 7.9 9.6e-10 37.9 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 GAO88957.1 - 2.7e-07 30.3 1.7 6e-06 25.9 0.2 2.3 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 GAO88957.1 - 5.2e-05 21.5 0.2 0.02 13.0 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Reg_prop PF07494.6 GAO88957.1 - 0.0004 20.0 0.1 0.46 10.6 0.0 3.2 3 0 0 3 3 3 2 Two component regulator propeller PQQ_3 PF13570.1 GAO88957.1 - 0.13 12.6 0.3 15 6.0 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Sigma70_r1_2 PF00140.15 GAO88957.1 - 0.47 10.1 2.8 1.3 8.7 2.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 LSM14 PF12701.2 GAO88958.1 - 1.4e-31 108.1 0.0 2.8e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 GAO88958.1 - 6.8e-25 87.6 2.4 1.3e-24 86.7 1.6 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 GAO88958.1 - 0.019 14.8 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain Cyclase PF04199.8 GAO88959.1 - 9.5e-12 44.9 0.1 1.6e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase FAD_binding_3 PF01494.14 GAO88960.1 - 6.3e-16 58.3 0.8 1.2e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO88960.1 - 1.3e-08 34.7 0.6 2.8e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO88960.1 - 5.5e-07 28.8 1.8 1e-06 27.9 0.7 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO88960.1 - 9.2e-06 24.9 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO88960.1 - 0.00012 21.9 1.2 0.00023 21.1 0.8 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO88960.1 - 0.0003 19.7 3.3 0.0028 16.5 2.0 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAO88960.1 - 0.001 19.4 1.3 0.0018 18.6 0.3 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO88960.1 - 0.0017 17.4 0.1 0.097 11.7 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 GAO88960.1 - 0.0039 16.1 0.9 0.0063 15.4 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Rossmann-like PF10727.4 GAO88960.1 - 0.013 15.2 0.2 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.1 GAO88960.1 - 0.042 13.9 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAO88960.1 - 0.076 12.5 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAO88960.1 - 0.08 11.3 1.3 0.13 10.7 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 GAO88960.1 - 0.17 11.6 0.8 0.31 10.7 0.6 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 GAO88964.1 - 3e-21 75.7 0.0 4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO88964.1 - 4.9e-15 55.9 0.3 8e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAO88964.1 - 8.9e-06 24.9 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAO88964.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAO88964.1 - 0.00027 20.8 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAO88964.1 - 0.00049 18.8 0.0 0.0011 17.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAO88964.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAO88964.1 - 0.029 13.2 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 GAO88964.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.12 GAO88966.1 - 4.3e-93 311.8 10.4 4.3e-93 311.8 7.2 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 GAO88966.1 - 1.4e-43 148.6 1.1 1.4e-43 148.6 0.8 2.2 2 0 0 2 2 2 1 Pectinesterase Beta_helix PF13229.1 GAO88966.1 - 9.2e-06 25.4 27.0 9.2e-06 25.4 18.7 4.4 4 0 0 4 4 4 2 Right handed beta helix region Velvet PF11754.3 GAO88968.1 - 2.2e-59 200.5 0.0 3.9e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Velvet factor NmrA PF05368.8 GAO88969.1 - 3.7e-30 104.9 0.0 4.5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAO88969.1 - 7.7e-08 32.0 0.1 2.7e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO88969.1 - 1.4e-06 28.4 0.0 2.9e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO88969.1 - 1.5e-05 23.8 0.1 2.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAO88969.1 - 0.001 19.0 0.3 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain DXP_reductoisom PF02670.11 GAO88969.1 - 0.0011 19.5 0.1 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 GAO88969.1 - 0.0032 17.7 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO88969.1 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAO88969.1 - 0.018 14.0 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 GAO88969.1 - 0.035 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 GAO88969.1 - 0.041 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF829 PF05705.9 GAO88970.1 - 1.8e-53 181.7 0.0 3e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Rad51 PF08423.6 GAO88970.1 - 2.7e-24 85.4 0.0 4.4e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAO88970.1 - 1.4e-13 50.6 0.0 3.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAO88970.1 - 2.9e-08 33.1 0.0 8.5e-08 31.5 0.0 1.7 2 1 0 2 2 2 1 KaiC RecA PF00154.16 GAO88970.1 - 0.019 14.0 0.0 0.05 12.6 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_16 PF13191.1 GAO88970.1 - 0.024 14.6 0.4 6.5 6.6 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAO88970.1 - 0.064 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 GAO88970.1 - 0.2 10.9 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TraV PF09676.5 GAO88970.1 - 1.9 9.2 6.4 0.35 11.5 0.7 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) TRAPPC10 PF12584.3 GAO88971.1 - 7.6e-39 132.5 0.0 1.6e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 FA_desaturase PF00487.19 GAO88971.1 - 6.6e-25 88.0 14.7 1.3e-24 87.0 10.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 GAO88971.1 - 1.6e-06 28.1 0.0 5.1e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank PF00023.25 GAO88972.1 - 1.4e-13 49.8 3.2 2.5e-07 30.1 0.6 2.6 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 GAO88972.1 - 1.8e-11 43.8 0.1 8e-11 41.7 0.1 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 GAO88972.1 - 2.4e-11 43.7 0.0 4.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO88972.1 - 4.1e-11 42.7 1.5 9.9e-09 35.1 0.6 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO88972.1 - 1.2e-08 35.2 0.7 5e-07 30.0 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO88972.1 - 8.4e-08 31.7 0.5 0.0013 18.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Glyco_hydro_61 PF03443.9 GAO88973.1 - 5.6e-85 284.5 0.9 5.6e-85 284.5 0.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SUI1 PF01253.17 GAO88974.1 - 3.2e-17 62.1 0.3 6.5e-17 61.1 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dabb PF07876.7 GAO88975.1 - 8.7e-17 61.3 0.0 9.8e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 GAO88975.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase La PF05383.12 GAO88976.1 - 3.2e-18 65.2 0.0 5.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 GAO88976.1 - 2.2e-07 30.7 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO88976.1 - 1e-06 28.2 0.1 2.9e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO88976.1 - 0.00032 20.4 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 GAO88977.1 - 6.4e-165 549.4 2.1 6.4e-165 549.4 1.4 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 GAO88977.1 - 7.1e-10 37.9 0.1 1.8e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 GAO88977.1 - 0.0018 18.1 2.9 1.3 8.8 0.2 3.7 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 GAO88977.1 - 0.18 11.4 0.2 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Metal_resist PF13801.1 GAO88977.1 - 1.7 8.6 6.9 8 6.4 0.1 2.6 2 0 0 2 2 2 0 Heavy-metal resistance MFS_1 PF07690.11 GAO88978.1 - 5.2e-41 140.5 58.2 5.3e-40 137.2 40.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LicD PF04991.8 GAO88979.1 - 7.5e-38 130.6 3.0 1.6e-36 126.3 2.1 2.3 1 1 0 1 1 1 1 LicD family WLM PF08325.5 GAO88980.1 - 2.6e-48 164.3 0.4 4.7e-48 163.5 0.0 1.6 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 GAO88980.1 - 0.00011 22.0 0.9 0.00022 21.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 GAO88980.1 - 0.00022 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.18 GAO88980.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Peptidase_MA_2 PF13485.1 GAO88980.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Thiolase_N PF00108.18 GAO88981.1 - 4e-74 248.9 0.3 7.2e-74 248.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAO88981.1 - 1.3e-40 137.6 0.3 1.3e-40 137.6 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 GAO88981.1 - 0.0054 16.3 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 GAO88981.1 - 0.012 15.1 2.3 0.027 13.9 1.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DASH_Ask1 PF08655.5 GAO88983.1 - 5.4e-34 115.8 0.1 1.1e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.22 GAO88984.1 - 5.3e-48 162.4 0.0 1.9e-47 160.7 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAO88984.1 - 0.00057 19.9 7.4 0.0014 18.6 3.6 2.3 2 0 0 2 2 2 1 LIM domain zf-CHY PF05495.7 GAO88984.1 - 0.013 15.5 4.1 0.035 14.2 2.8 1.6 1 0 0 1 1 1 0 CHY zinc finger CmcI PF04989.7 GAO88984.1 - 0.16 11.2 0.8 0.33 10.2 0.6 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Zn-ribbon_8 PF09723.5 GAO88984.1 - 2.4 8.1 9.5 0.77 9.7 2.4 2.8 2 1 1 3 3 3 0 Zinc ribbon domain ABC_membrane PF00664.18 GAO88985.1 - 3.1e-74 249.8 22.2 1e-38 133.3 5.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAO88985.1 - 4.1e-63 211.7 0.0 3.7e-30 105.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAO88985.1 - 2.6e-17 62.7 0.5 1.5e-06 27.5 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 GAO88985.1 - 7.8e-11 41.2 0.3 0.00015 20.4 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 GAO88985.1 - 1.1e-09 37.7 0.0 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 GAO88985.1 - 7.5e-09 35.9 0.0 0.27 11.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 GAO88985.1 - 1e-07 32.1 0.0 0.21 11.7 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.12 GAO88985.1 - 5.2e-07 29.7 0.0 0.015 15.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 GAO88985.1 - 5.4e-07 30.4 0.0 0.03 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAO88985.1 - 6.6e-07 28.9 0.1 0.038 13.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAO88985.1 - 1.9e-06 28.0 7.6 0.011 15.7 0.5 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 GAO88985.1 - 8.2e-06 25.7 0.0 0.13 12.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAO88985.1 - 1.1e-05 24.6 0.0 0.26 10.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAO88985.1 - 1.4e-05 24.6 0.1 0.27 10.6 0.0 3.3 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 GAO88985.1 - 3.5e-05 23.6 2.1 0.11 12.3 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 GAO88985.1 - 4.1e-05 23.2 0.0 0.5 9.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 GAO88985.1 - 6.2e-05 23.4 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 GAO88985.1 - 0.00029 20.3 0.0 0.044 13.2 0.0 2.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 GAO88985.1 - 0.0031 17.8 0.3 3.5 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 GAO88985.1 - 0.0036 17.0 0.0 8.1 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 GAO88985.1 - 0.0098 15.3 0.0 0.69 9.3 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 GAO88985.1 - 0.0099 15.5 0.0 2.8 7.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAO88985.1 - 0.015 15.2 0.4 8.5 6.3 0.1 3.1 2 2 1 3 3 3 0 AAA domain DUF3987 PF13148.1 GAO88985.1 - 0.016 13.8 0.0 4 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 GAO88985.1 - 0.066 13.1 0.1 16 5.4 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Rad17 PF03215.10 GAO88985.1 - 0.22 10.1 0.0 11 4.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF2207 PF09972.4 GAO88985.1 - 0.62 8.5 2.1 3.8 5.9 1.4 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CLASP_N PF12348.3 GAO88986.1 - 6e-158 523.0 3.2 2.5e-90 301.7 0.0 2.5 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 GAO88986.1 - 9.3e-10 37.7 2.5 0.36 11.0 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 GAO88986.1 - 3.9e-06 27.0 0.8 0.84 9.9 0.0 4.7 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 GAO88986.1 - 1.6e-05 24.8 0.3 0.0067 16.2 0.0 4.1 3 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 GAO88986.1 - 0.053 14.0 0.3 25 5.5 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat BSP PF04450.7 GAO88987.1 - 5.4e-83 277.4 0.0 6.4e-83 277.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 GAO88987.1 - 0.00014 21.8 0.0 0.00026 21.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 GAO88987.1 - 0.0054 16.4 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 SprT-like family DUF2268 PF10026.4 GAO88987.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Ribonucleas_3_3 PF14622.1 GAO88988.1 - 3.5e-08 33.4 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 GAO88988.1 - 1.7e-06 28.4 0.4 4.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 GAO88988.1 - 2.3e-06 28.0 0.0 6.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain PfkB PF00294.19 GAO88990.1 - 4.8e-13 48.9 0.0 3.5e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.14 GAO88991.1 - 1e-83 281.2 10.8 1.4e-65 221.6 0.1 2.2 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 GAO88991.1 - 3.6e-55 185.6 0.8 4.8e-55 185.2 0.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 GAO88991.1 - 0.032 13.6 2.9 0.85 9.0 1.6 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF4210 PF13915.1 GAO88992.1 - 6.3e-28 96.8 0.2 2.6e-27 94.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 GAO88992.1 - 1.1e-22 79.5 0.5 3.2e-22 78.1 0.4 1.9 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 GAO88993.1 - 0.0011 18.8 3.6 0.0011 18.8 2.5 2.3 1 1 1 2 2 2 1 rRNA processing Sec5 PF15469.1 GAO88994.1 - 2.7e-33 115.2 0.0 4.3e-32 111.3 0.0 2.5 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 GAO88994.1 - 3e-06 26.9 0.1 1.4e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Iso_dh PF00180.15 GAO88995.1 - 3.2e-100 335.4 0.0 3.8e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 GAO88995.1 - 0.0057 16.5 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif Eaf7 PF07904.8 GAO88996.1 - 1.8e-18 66.3 0.0 3.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 GAO88996.1 - 3.9 5.2 5.9 4.5 5.0 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Spc97_Spc98 PF04130.8 GAO88997.1 - 2e-90 303.6 0.2 2.5e-90 303.3 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Mo-co_dimer PF03404.11 GAO88998.1 - 2e-56 189.2 0.0 4.5e-56 188.0 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 GAO88998.1 - 2e-47 160.7 0.0 4.2e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 GAO88998.1 - 3.3e-31 107.3 0.0 5.4e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAO88998.1 - 4.6e-30 104.3 0.0 1.2e-29 103.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 GAO88998.1 - 6.6e-20 70.6 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 GAO88998.1 - 0.012 15.4 0.0 0.24 11.2 0.0 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain NIR_SIR PF01077.17 GAO88999.1 - 4.7e-32 110.5 0.0 9.4e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 GAO88999.1 - 1.3e-29 103.4 0.1 2.5e-29 102.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO88999.1 - 2.8e-17 62.8 2.2 2.3e-16 59.9 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 GAO88999.1 - 3.2e-16 58.9 0.0 6.4e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 GAO88999.1 - 2e-13 50.1 2.9 8.7e-12 44.9 1.9 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 GAO88999.1 - 4.1e-13 48.7 0.1 1e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 GAO88999.1 - 8.8e-11 41.2 0.0 2.4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 GAO88999.1 - 4.6e-05 23.5 0.0 0.046 13.7 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO88999.1 - 0.0042 16.8 0.6 2.4 7.9 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAO88999.1 - 0.014 14.3 0.0 0.87 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Rep_N PF08724.5 GAO88999.1 - 0.16 11.5 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Rep protein catalytic domain like MFS_1 PF07690.11 GAO89000.1 - 1.2e-28 99.8 25.9 1.2e-28 99.8 17.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF718 PF05336.8 GAO89001.1 - 1.9e-35 120.8 0.1 2.1e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) SlyX PF04102.7 GAO89002.1 - 0.015 15.6 3.2 0.061 13.6 0.7 2.8 3 0 0 3 3 3 0 SlyX FTA4 PF13093.1 GAO89003.1 - 2.9e-71 239.3 9.9 3.3e-71 239.1 6.9 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Mnd1 PF03962.10 GAO89003.1 - 0.0014 18.3 2.3 0.0014 18.3 1.6 1.9 1 1 1 2 2 2 1 Mnd1 family Tweety PF04906.8 GAO89003.1 - 0.51 8.7 5.1 3.9 5.7 0.3 2.0 1 1 1 2 2 2 0 Tweety FKBP_N PF01346.13 GAO89003.1 - 0.7 9.9 3.2 2.7 8.0 0.1 2.6 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FUSC PF04632.7 GAO89003.1 - 0.81 8.0 6.0 0.91 7.8 4.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 GAO89003.1 - 0.89 7.8 3.8 0.55 8.5 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Cortex-I_coil PF09304.5 GAO89003.1 - 1.3 9.1 12.7 1.7 8.7 6.3 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1690 PF07956.6 GAO89003.1 - 1.7 8.5 5.9 0.79 9.6 0.1 2.4 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Seryl_tRNA_N PF02403.17 GAO89003.1 - 3 7.8 8.8 4.4 7.3 3.2 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.8 GAO89003.1 - 3.5 8.4 7.1 12 6.6 0.1 2.7 1 1 2 3 3 3 0 Occludin homology domain Vir_act_alpha_C PF10400.4 GAO89003.1 - 3.7 7.9 10.8 2.9 8.2 4.7 2.6 2 1 1 3 3 3 0 Virulence activator alpha C-term DUF4239 PF14023.1 GAO89003.1 - 4.3 6.6 5.5 7.3 5.8 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) HAD_2 PF13419.1 GAO89004.1 - 4.2e-20 72.6 0.0 5.8e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO89004.1 - 2.6e-06 27.0 0.1 6.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like VWA_2 PF13519.1 GAO89004.1 - 0.077 13.0 0.1 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Ribosomal_L18p PF00861.17 GAO89005.1 - 4.4e-43 146.2 0.2 4.4e-43 146.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAO89005.1 - 2.7e-34 117.6 9.0 2.7e-34 117.6 6.3 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_4 PF12799.2 GAO89006.1 - 0.0029 17.1 6.8 0.23 11.1 0.0 5.3 4 2 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAO89006.1 - 0.0043 16.9 2.6 2.1e+02 2.4 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat DUF3135 PF11333.3 GAO89006.1 - 0.041 14.0 0.3 0.4 10.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) ABC_membrane_2 PF06472.10 GAO89007.1 - 1.8e-105 352.0 0.3 3.2e-105 351.2 0.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAO89007.1 - 2.4e-18 66.7 0.0 4.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAO89007.1 - 0.00015 21.8 0.0 0.00044 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAO89007.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAO89007.1 - 0.022 14.2 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO89007.1 - 0.033 14.1 0.3 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 GAO89007.1 - 0.033 13.4 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Glyco_transf_22 PF03901.12 GAO89007.1 - 0.058 12.3 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Mg_chelatase PF01078.16 GAO89007.1 - 0.083 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 GAO89007.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phosphorylase PF00343.15 GAO89008.1 - 0 1079.1 1.0 0 1078.9 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 GAO89008.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform G-alpha PF00503.15 GAO89009.1 - 1.3e-119 399.3 0.1 1.7e-119 399.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAO89009.1 - 5.5e-12 45.2 0.4 2.1e-10 40.1 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Pkinase PF00069.20 GAO89010.1 - 2.2e-73 246.6 0.0 2.7e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89010.1 - 3.1e-31 108.3 0.0 4.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAO89010.1 - 3.6e-05 22.9 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAO89010.1 - 0.00019 20.4 0.0 0.046 12.6 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 GAO89010.1 - 0.00056 19.7 0.0 0.0018 18.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAO89010.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 GAO89011.1 - 2.1e-142 474.1 0.0 2.6e-142 473.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 GAO89011.1 - 4.6e-08 32.7 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 GAO89011.1 - 4.1e-05 23.0 5.2 0.00094 18.5 0.5 3.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 GAO89012.1 - 3.2e-216 719.4 14.7 3.2e-216 719.4 10.2 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 GAO89012.1 - 2.4e-27 94.5 5.6 2.4e-27 94.5 3.9 3.5 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 GAO89012.1 - 0.25 11.4 8.6 9.5 6.3 0.1 4.5 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 GAO89012.1 - 4.1 6.8 10.8 4.7 6.6 0.8 2.4 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Cupin_2 PF07883.6 GAO89013.1 - 6.2e-09 35.2 0.1 9.8e-09 34.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAO89013.1 - 4.7e-07 29.3 0.0 6.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 GAO89013.1 - 1.5e-05 24.7 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 GAO89013.1 - 0.00032 20.6 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.7 GAO89013.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Mit_KHE1 PF10173.4 GAO89015.1 - 2.7e-67 226.2 1.0 4.3e-67 225.6 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Sirohm_synth_C PF14823.1 GAO89015.1 - 0.064 12.5 0.5 0.16 11.2 0.1 1.8 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal 4HBT_3 PF13622.1 GAO89016.1 - 1.8e-47 162.2 2.5 2.1e-47 162.0 1.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily SNF2_N PF00176.18 GAO89017.1 - 5.9e-69 232.1 0.1 1.2e-68 231.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO89017.1 - 3.4e-16 58.8 0.4 1.3e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89017.1 - 1.2e-05 25.1 0.0 0.0001 22.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2538 PF10804.3 GAO89017.1 - 0.047 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) End3 PF12761.2 GAO89018.1 - 1e-75 253.6 0.1 1.5e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 GAO89018.1 - 2.1e-49 165.5 0.1 6.9e-47 157.4 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 GAO89018.1 - 1.9e-08 33.0 0.3 2.9e-07 29.2 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 GAO89018.1 - 8.4e-08 31.7 0.3 1.2e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAO89018.1 - 2.3e-06 26.9 0.6 0.0002 20.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 GAO89018.1 - 6.1e-06 26.2 0.3 0.00014 21.8 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 GAO89018.1 - 0.0006 19.0 0.2 0.002 17.3 0.1 1.9 1 0 0 1 1 1 1 EF hand Rabaptin PF03528.10 GAO89018.1 - 0.0016 18.2 1.6 0.0053 16.6 1.1 2.0 1 1 0 1 1 1 1 Rabaptin FANCAA PF15146.1 GAO89018.1 - 0.094 11.6 0.2 0.16 10.8 0.2 1.3 1 0 0 1 1 1 0 Fanconi anemia-associated TPR_MLP1_2 PF07926.7 GAO89018.1 - 0.32 10.7 7.3 0.075 12.7 0.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 GAO89018.1 - 1.4 8.4 4.8 18 4.8 3.8 2.2 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 GAO89018.1 - 2 7.3 8.8 3.5 6.5 5.8 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DSPc PF00782.15 GAO89020.1 - 5e-14 52.0 0.0 1.2e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 GAO89020.1 - 0.00081 18.3 0.0 0.0013 17.6 0.0 1.4 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase zf-C2H2_4 PF13894.1 GAO89021.1 - 1.7e-07 31.1 10.1 0.063 13.6 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO89021.1 - 0.00021 21.4 16.1 0.47 10.8 2.4 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO89021.1 - 0.01 16.1 11.8 0.028 14.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain TMF_DNA_bd PF12329.3 GAO89021.1 - 0.057 13.2 1.2 0.11 12.3 0.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-H2C2_5 PF13909.1 GAO89021.1 - 0.097 12.9 1.1 2.6 8.4 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain IncA PF04156.9 GAO89021.1 - 0.16 11.5 0.5 0.28 10.7 0.3 1.3 1 0 0 1 1 1 0 IncA protein Microtub_assoc PF07989.6 GAO89021.1 - 0.98 9.2 4.0 0.83 9.5 1.0 2.0 2 0 0 2 2 2 0 Microtubule associated Cwf_Cwc_15 PF04889.7 GAO89021.1 - 2.7 7.6 6.0 4.5 6.9 4.2 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UPF1_Zn_bind PF09416.5 GAO89022.1 - 2.8e-73 244.5 1.7 2.8e-73 244.5 1.2 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 GAO89022.1 - 1.3e-59 200.9 0.0 2e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAO89022.1 - 3.4e-57 193.7 1.0 5.1e-57 193.1 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO89022.1 - 2.5e-14 52.7 0.2 6.8e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAO89022.1 - 6.5e-12 45.4 0.2 1.2e-10 41.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 GAO89022.1 - 3.1e-08 33.6 0.0 6.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAO89022.1 - 8.7e-05 22.1 0.1 0.67 9.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAO89022.1 - 0.00068 18.7 0.6 0.006 15.5 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 GAO89022.1 - 0.00071 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 GAO89022.1 - 0.0018 17.2 0.1 0.37 9.6 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 GAO89022.1 - 0.004 16.4 0.0 0.035 13.4 0.0 2.1 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 GAO89022.1 - 0.0082 15.6 0.0 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 GAO89022.1 - 0.03 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 GAO89022.1 - 0.037 13.9 0.1 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 GAO89022.1 - 0.038 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 GAO89022.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 GAO89022.1 - 0.078 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 GAO89022.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAO89022.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.1 GAO89022.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 GAO89022.1 - 0.23 11.6 0.4 0.63 10.2 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-RanBP PF00641.13 GAO89022.1 - 6.1 6.0 8.2 0.37 9.9 1.6 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Brix PF04427.13 GAO89023.1 - 2.1e-45 154.7 0.0 2.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain BRCT PF00533.21 GAO89024.1 - 1.3e-08 34.9 0.3 2.7e-08 33.8 0.1 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAO89024.1 - 1.2e-07 31.4 0.2 1.2e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 twin BRCT domain WGR PF05406.10 GAO89024.1 - 3.5e-06 26.8 0.0 1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 WGR domain HK97-gp10_like PF04883.7 GAO89024.1 - 0.013 16.4 0.7 0.035 15.0 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF2500 PF10694.4 GAO89024.1 - 0.15 12.0 1.1 0.25 11.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) IGPS PF00218.16 GAO89025.1 - 8.8e-99 329.6 0.0 3e-98 327.9 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 GAO89025.1 - 2.6e-58 196.8 0.0 1.9e-56 190.7 0.0 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 GAO89025.1 - 4.2e-51 173.1 0.0 7e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAO89025.1 - 3.9e-05 23.1 0.3 0.0002 20.9 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 GAO89025.1 - 0.00056 19.4 0.1 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 GAO89025.1 - 0.019 13.9 0.3 0.072 12.0 0.0 2.1 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 GAO89025.1 - 0.032 13.4 0.0 0.097 11.9 0.0 1.8 1 0 0 1 1 1 0 Histidine biosynthesis protein Nup188 PF10487.4 GAO89026.1 - 1.9e-52 178.3 0.0 6.1e-52 176.7 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 AMP-binding PF00501.23 GAO89027.1 - 5.4e-87 291.8 0.0 6.9e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO89027.1 - 1.6e-11 45.0 0.4 3.3e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3184 PF11380.3 GAO89027.1 - 0.097 10.5 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Use1 PF09753.4 GAO89028.1 - 1.2e-11 44.5 2.9 4.1e-11 42.7 2.0 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 GAO89028.1 - 0.012 15.1 0.4 0.021 14.3 0.3 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Pox_A11 PF05061.8 GAO89028.1 - 0.032 13.3 0.9 0.049 12.7 0.6 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein MSP1_C PF07462.6 GAO89028.1 - 0.076 11.3 7.9 0.12 10.7 5.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ADIP PF11559.3 GAO89028.1 - 0.98 9.3 14.0 3.1 7.7 2.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding G-alpha PF00503.15 GAO89029.1 - 1.7e-134 448.3 1.6 2.1e-134 448.0 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAO89029.1 - 1.9e-15 56.5 1.6 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 GAO89029.1 - 8.5e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 GAO89029.1 - 0.0014 19.0 0.7 2.7 8.5 0.1 2.9 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 GAO89029.1 - 0.0081 15.3 3.3 0.21 10.6 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 GAO89029.1 - 0.0094 15.4 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 GAO89029.1 - 0.018 14.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 GAO89029.1 - 0.025 14.9 0.1 0.052 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 GAO89029.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 GAO89029.1 - 0.094 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAO89029.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1771 PF08590.5 GAO89030.1 - 7.3e-25 86.7 7.3 7.3e-25 86.7 5.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAO89030.1 - 1.1e-16 60.7 0.4 3.7e-16 59.0 0.3 1.9 1 0 0 1 1 1 1 Smr domain PspA_IM30 PF04012.7 GAO89030.1 - 0.13 11.6 5.7 0.22 10.8 4.0 1.3 1 1 0 1 1 1 0 PspA/IM30 family polyprenyl_synt PF00348.12 GAO89031.1 - 4.8e-60 202.6 0.0 6.1e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 GAO89032.1 - 1.4e-101 338.9 0.0 1.6e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF2731 PF10806.3 GAO89033.1 - 6.4e-07 29.6 0.1 1.5e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 GAO89033.1 - 9e-05 22.6 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 GAO89033.1 - 0.00077 19.3 0.0 0.37 10.6 0.0 2.2 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_3 PF14497.1 GAO89033.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RseA_C PF03873.8 GAO89033.1 - 0.14 12.0 0.3 0.36 10.7 0.2 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Metallothio_PEC PF02068.11 GAO89034.1 - 3 8.2 25.1 0.053 13.8 2.8 3.4 3 0 0 3 3 3 0 Plant PEC family metallothionein DUF543 PF04418.7 GAO89035.1 - 6.1e-27 93.3 0.0 6.8e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 GAO89036.1 - 3.9e-71 239.2 0.5 5.4e-70 235.4 0.0 2.9 3 0 0 3 3 3 1 Urb2/Npa2 family Transp_cyt_pur PF02133.10 GAO89037.1 - 4.1e-146 486.9 36.1 5e-146 486.7 25.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3669 PF12417.3 GAO89037.1 - 3.1e-22 78.0 0.8 1.7e-21 75.7 0.1 2.4 3 0 0 3 3 3 1 Zinc finger protein p450 PF00067.17 GAO89038.1 - 5.8e-31 107.5 0.0 2.3e-30 105.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 GAO89039.1 - 2.1e-07 30.5 0.0 5.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) A_deaminase PF00962.17 GAO89040.1 - 1.4e-25 89.9 0.0 1.7e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase PI-PLC-X PF00388.14 GAO89041.1 - 3.1e-58 195.3 0.0 5.7e-58 194.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAO89041.1 - 4e-41 139.6 0.0 3e-40 136.8 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 GAO89041.1 - 1.6e-06 28.0 0.0 5.6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 GAO89041.1 - 0.008 16.2 0.6 0.049 13.7 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAO89041.1 - 0.011 15.0 0.2 0.097 12.0 0.0 2.5 2 0 0 2 2 2 0 EF hand GDPD PF03009.12 GAO89041.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.1 GAO89041.1 - 0.014 15.1 1.8 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 GAO89041.1 - 0.026 14.1 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Coatomer_E PF04733.9 GAO89042.1 - 6.4e-56 189.6 1.5 6.3e-37 127.3 0.1 2.0 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.1 GAO89042.1 - 6.5e-10 39.2 19.4 0.00066 19.9 1.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89042.1 - 1.4e-07 31.5 20.9 0.0008 19.8 0.2 5.9 4 1 3 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAO89042.1 - 5.1e-07 29.7 1.1 0.046 13.8 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAO89042.1 - 6.2e-07 29.9 22.4 0.011 16.3 3.2 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAO89042.1 - 3.3e-06 27.1 2.7 0.019 15.3 0.4 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO89042.1 - 0.00051 19.6 7.2 0.18 11.4 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 GAO89042.1 - 0.0015 18.5 2.5 1.6 9.1 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO89042.1 - 0.0031 17.8 21.1 2.1 9.0 0.4 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAO89042.1 - 0.012 15.4 13.3 0.038 13.9 0.8 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAO89042.1 - 0.014 14.4 0.7 0.014 14.4 0.5 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89042.1 - 0.019 14.8 16.3 0.062 13.2 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAO89042.1 - 0.065 13.0 6.6 1.9 8.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAO89042.1 - 0.13 11.9 4.2 0.86 9.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAO89042.1 - 0.61 10.0 3.6 16 5.6 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.8 GAO89042.1 - 1.5 8.4 5.3 7.3 6.1 0.2 3.0 3 0 0 3 3 3 0 HemY protein N-terminus BTAD PF03704.12 GAO89042.1 - 6 7.1 11.3 1.9 8.7 2.2 3.0 2 2 1 3 3 3 0 Bacterial transcriptional activator domain Abhydrolase_3 PF07859.8 GAO89043.1 - 3.9e-31 108.2 0.1 5.5e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO89043.1 - 1e-17 63.8 0.0 1.4e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAO89043.1 - 4.8e-07 29.6 0.2 6.9e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAO89043.1 - 0.00043 19.7 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 GAO89043.1 - 0.0063 15.7 0.0 0.021 14.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 GAO89043.1 - 0.065 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PMI_typeI PF01238.16 GAO89044.1 - 1.6e-139 465.0 0.0 2.1e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 GAO89044.1 - 0.0032 17.1 0.0 0.51 10.0 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.6 GAO89044.1 - 0.0045 16.4 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Cupin domain DUF1325 PF07039.6 GAO89045.1 - 2.2e-28 98.4 0.3 9.4e-27 93.1 0.1 2.3 1 1 1 2 2 2 2 SGF29 tudor-like domain GTP_cyclohydro2 PF00925.15 GAO89046.1 - 1e-56 190.8 0.0 5e-52 175.5 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF3425 PF11905.3 GAO89046.1 - 1.2e-37 128.8 3.8 2.3e-37 127.9 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO89046.1 - 0.0043 16.9 9.3 0.018 14.9 4.8 2.5 1 1 1 2 2 2 1 bZIP transcription factor T2SM_b PF10741.4 GAO89046.1 - 0.11 12.1 6.2 0.56 9.8 0.5 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b bZIP_2 PF07716.10 GAO89046.1 - 0.24 11.2 9.0 0.57 10.0 6.3 1.6 1 1 0 1 1 1 0 Basic region leucine zipper NAD_binding_2 PF03446.10 GAO89047.1 - 3.9e-26 91.8 0.1 5.4e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAO89047.1 - 2.4e-12 46.9 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAO89047.1 - 0.024 15.0 0.0 0.09 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.14 GAO89048.1 - 2e-111 372.2 0.0 2.1e-99 332.6 0.0 2.0 2 0 0 2 2 2 2 Actin EamA PF00892.15 GAO89049.1 - 1.6e-14 54.0 23.9 1.2e-07 31.8 10.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 GAO89049.1 - 1.4e-06 28.4 18.5 7.1e-05 22.9 0.2 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 GAO89049.1 - 0.00073 19.2 16.5 0.0055 16.3 5.7 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 GAO89049.1 - 0.00083 18.5 0.1 0.00083 18.5 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 GAO89049.1 - 0.019 13.8 5.1 0.0063 15.3 1.7 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 GAO89049.1 - 0.66 8.8 13.9 1.7 7.4 2.9 2.1 1 1 1 2 2 2 0 UAA transporter family DUF202 PF02656.10 GAO89049.1 - 0.98 9.6 14.1 0.28 11.4 2.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 GAO89050.1 - 1e-20 73.7 17.8 1.4e-20 73.3 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SLAC1 PF03595.12 GAO89051.1 - 6.6e-97 324.1 51.1 7.5e-97 323.9 35.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Aldo_ket_red PF00248.16 GAO89052.1 - 1e-56 191.8 0.0 1.1e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S9 PF00326.16 GAO89052.1 - 0.0073 15.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Tubulin PF00091.20 GAO89053.1 - 3.3e-73 246.0 0.0 5.4e-73 245.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAO89053.1 - 2e-45 153.8 1.1 2.3e-45 153.6 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAO89053.1 - 8.8e-07 28.9 0.0 2.7e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF1754 PF08555.5 GAO89054.1 - 2.6e-18 66.3 11.6 4.8e-18 65.5 8.1 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) FYVE_2 PF02318.11 GAO89054.1 - 2 8.3 4.2 23 4.9 0.0 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger PTPA PF03095.10 GAO89057.1 - 6.1e-111 370.3 0.0 7.2e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.10 GAO89058.1 - 5.1e-27 93.8 1.6 5.1e-27 93.8 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ni_hydr_CYTB PF01292.15 GAO89058.1 - 0.0062 15.9 0.9 0.0088 15.4 0.6 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 SOG2 PF10428.4 GAO89058.1 - 0.13 10.8 5.4 0.14 10.7 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cu_amine_oxid PF01179.15 GAO89059.1 - 1.6e-161 537.6 0.2 2.2e-161 537.2 0.2 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAO89059.1 - 1.8e-09 37.5 0.1 3.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAO89059.1 - 5.9e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF3115 PF11312.3 GAO89061.1 - 1.9e-118 394.9 0.0 2.2e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Band_7 PF01145.20 GAO89062.1 - 1.2e-24 87.1 6.0 1.2e-24 87.1 4.2 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family UcrQ PF02939.11 GAO89063.1 - 9.9e-28 95.7 0.0 1.2e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 UcrQ family Spermine_synth PF01564.12 GAO89064.1 - 2.9e-97 324.4 0.0 3.4e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 GAO89064.1 - 3.1e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO89064.1 - 0.00051 20.5 0.0 0.0013 19.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO89064.1 - 0.00057 20.3 0.1 0.0088 16.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAO89064.1 - 0.013 14.7 0.2 0.048 12.8 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase MTS PF05175.9 GAO89064.1 - 0.03 13.7 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF43 PF01861.11 GAO89064.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 GAO89064.1 - 0.093 12.4 0.0 0.35 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 GAO89064.1 - 0.099 13.4 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAO89064.1 - 0.12 12.8 0.0 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.6 GAO89064.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Transketolase_N PF00456.16 GAO89065.1 - 4.6e-150 499.0 0.0 6.3e-150 498.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAO89065.1 - 2.4e-44 150.9 0.0 4.8e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAO89065.1 - 1.9e-12 47.1 0.0 4.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 GAO89065.1 - 9e-07 27.8 0.0 2.1e-06 26.7 0.1 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAO89065.1 - 1.6e-06 27.2 0.0 0.00037 19.5 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.13 GAO89066.1 - 4e-36 124.2 0.1 7.4e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89066.1 - 4.8e-08 32.7 14.7 8.1e-08 32.0 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 GAO89066.1 - 0.27 11.5 8.8 1.9 8.7 0.4 2.4 2 0 0 2 2 2 0 Striatin family SET PF00856.23 GAO89067.1 - 6.5e-06 26.5 0.0 1.4e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 SET domain GET2 PF08690.5 GAO89068.1 - 0.055 12.6 0.8 0.069 12.3 0.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 MMR_HSR1_C PF08438.5 GAO89069.1 - 1.1e-32 112.4 0.0 2.6e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 GAO89069.1 - 2.3e-18 66.2 0.0 5.3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO89069.1 - 1.4e-08 34.1 0.0 1.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAO89069.1 - 0.0019 18.0 1.7 0.17 11.6 0.3 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 GAO89069.1 - 0.002 17.5 0.0 0.49 9.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAO89069.1 - 0.035 13.9 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO89069.1 - 0.06 13.6 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAO89069.1 - 0.076 11.7 0.0 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 GAO89069.1 - 0.12 11.8 0.1 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 GAO89069.1 - 0.14 11.6 0.1 0.76 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain KTI12 PF08433.5 GAO89069.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Herpes_UL32 PF06070.6 GAO89070.1 - 0.53 8.6 5.9 0.57 8.5 4.1 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ribosomal_L7Ae PF01248.21 GAO89072.1 - 1.3e-18 66.3 1.5 1.3e-18 66.3 1.1 2.9 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAD PF05557.8 GAO89073.1 - 3.1e-58 197.4 77.2 4.2e-49 167.3 53.7 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Tropomyosin_1 PF12718.2 GAO89073.1 - 0.0021 17.9 21.9 0.0021 17.9 15.2 6.4 2 1 3 6 6 6 2 Tropomyosin like muHD PF10291.4 GAO89074.1 - 7e-90 300.6 0.0 9.5e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 GAO89074.1 - 1.3e-12 47.7 0.0 3.8e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.6 GAO89074.1 - 0.18 11.7 1.1 0.43 10.4 0.1 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Transpep_BrtH PF14399.1 GAO89074.1 - 0.31 10.2 1.9 0.35 10.1 0.3 1.8 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Mnd1 PF03962.10 GAO89074.1 - 1.5 8.4 5.8 3.5 7.2 1.7 2.4 2 0 0 2 2 2 0 Mnd1 family Pkinase PF00069.20 GAO89075.1 - 1.1e-42 146.0 0.0 1.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89075.1 - 2.6e-17 62.7 0.0 3.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO89075.1 - 1.3e-06 28.3 0.4 0.025 14.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAO89075.1 - 1.5e-05 24.0 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAO89075.1 - 0.0058 15.7 0.3 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO89075.1 - 0.027 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL KIX PF02172.11 GAO89075.1 - 0.16 12.0 0.3 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 KIX domain DUF1088 PF06469.6 GAO89075.1 - 0.17 11.3 0.4 0.39 10.1 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) SH3_9 PF14604.1 GAO89076.1 - 3.1e-10 39.4 0.0 5.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO89076.1 - 1.5e-07 30.7 0.0 3.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAO89076.1 - 1.6e-07 30.6 0.0 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.6 GAO89076.1 - 8.6e-06 25.4 11.1 2.3e-05 23.9 7.7 1.7 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 GAO89076.1 - 0.044 13.0 0.1 0.044 13.0 0.0 3.0 3 0 0 3 3 3 0 Transmembrane alpha-helix domain DUF2627 PF11118.3 GAO89076.1 - 0.064 13.3 0.4 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF2668 PF10873.3 GAO89076.1 - 0.094 12.8 0.0 0.094 12.8 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) DUF1049 PF06305.6 GAO89076.1 - 0.17 11.3 0.1 0.4 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) OPT PF03169.10 GAO89077.1 - 1.8e-174 581.6 22.5 2e-174 581.4 15.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 2-Hacid_dh_C PF02826.14 GAO89078.1 - 1.5e-41 141.4 0.0 2.3e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO89078.1 - 7.6e-20 70.7 0.0 9.1e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 GAO89078.1 - 0.00013 22.3 0.1 0.00035 20.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 GAO89078.1 - 0.00015 21.7 0.7 0.00052 20.0 0.2 1.9 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_2 PF03446.10 GAO89078.1 - 0.00052 19.8 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 GAO89078.1 - 0.00093 18.7 2.3 0.13 11.7 0.7 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 GAO89078.1 - 0.0022 18.3 0.0 0.0071 16.6 0.0 1.8 2 1 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 GAO89078.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 GAO89078.1 - 0.0053 16.1 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 GAO89078.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAO89078.1 - 0.1 12.3 0.2 4.5 6.9 0.2 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 GAO89079.1 - 5.6e-79 265.7 0.0 1.3e-77 261.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO89079.1 - 5.5e-42 143.2 0.0 1.1e-41 142.2 0.0 1.5 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAO89079.1 - 5.8e-05 22.2 0.1 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAO89079.1 - 6e-05 21.6 0.2 9.3e-05 21.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAO89079.1 - 0.00028 19.8 0.4 0.00045 19.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO89079.1 - 0.0012 17.8 0.4 0.0027 16.6 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO89079.1 - 0.0017 18.2 0.2 0.0081 16.0 0.3 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO89079.1 - 0.0029 16.5 0.1 0.0098 14.7 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAO89079.1 - 0.0029 17.5 0.1 0.0072 16.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAO89079.1 - 0.0052 15.9 0.5 0.0077 15.3 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAO89079.1 - 0.076 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAO89079.1 - 0.12 12.1 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 ThiF family Zip PF02535.17 GAO89080.1 - 0.07 12.1 2.3 0.084 11.8 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MSA-2c PF12238.3 GAO89080.1 - 0.18 11.4 5.0 0.23 11.0 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pox_Ag35 PF03286.9 GAO89080.1 - 0.55 9.7 4.1 0.71 9.3 2.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sod_Cu PF00080.15 GAO89081.1 - 0.079 13.1 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) Rav1p_C PF12234.3 GAO89082.1 - 5.7e-279 926.6 0.0 7.3e-279 926.2 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 GAO89082.1 - 1.1e-06 28.2 0.3 0.34 10.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Sfi1 PF08457.5 GAO89083.1 - 9.8e-222 737.4 89.9 9.8e-222 737.4 62.3 2.5 2 1 1 3 3 3 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 GAO89084.1 - 2.2e-223 742.6 0.0 3.4e-223 742.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAO89084.1 - 6.5e-28 97.4 0.0 1.7e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAO89084.1 - 6.2e-18 64.6 0.0 5.8e-08 31.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAO89084.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.9 GAO89085.1 - 7.3e-112 373.1 0.0 1.7e-111 371.9 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 GAO89085.1 - 1.3e-08 34.8 31.1 1.3e-08 34.8 21.6 4.6 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 GAO89085.1 - 7.1e-07 28.9 86.4 5.6e-06 26.0 31.3 2.5 1 1 1 2 2 2 2 Intermediate filament protein WEMBL PF05701.6 GAO89085.1 - 0.00079 18.0 38.5 0.00079 18.0 26.7 3.3 1 1 2 3 3 3 1 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 GAO89085.1 - 0.045 13.5 29.0 0.34 10.7 2.5 5.7 2 1 5 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 GAO89085.1 - 0.1 9.9 71.5 0.0014 16.0 33.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAO89085.1 - 2.3 6.5 54.3 1.1 7.6 12.2 2.7 1 1 0 2 2 2 0 AAA domain Shugoshin_N PF07558.6 GAO89085.1 - 3.8 7.3 10.4 0.72 9.6 0.1 4.9 5 1 1 6 6 6 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.1 GAO89085.1 - 4.3 6.2 54.6 1.1 8.1 23.2 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.7 GAO89085.1 - 4.4 6.3 29.2 0.89 8.6 1.2 4.1 1 1 4 5 5 5 0 Reovirus sigma C capsid protein XRN_N PF03159.13 GAO89086.1 - 9e-111 368.9 3.4 1.6e-110 368.0 0.0 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 GAO89086.1 - 0.078 12.9 2.8 0.14 12.1 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.15 GAO89087.1 - 1.8e-126 421.9 0.0 2.8e-126 421.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 GAO89087.1 - 2e-96 321.9 0.0 3.7e-96 321.0 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 GAO89087.1 - 9e-64 215.1 0.0 1.8e-63 214.1 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAO89087.1 - 8.4e-38 129.7 0.0 8.2e-37 126.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAO89087.1 - 2.1e-24 85.4 0.0 4.9e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAO89087.1 - 1.4e-11 44.6 0.0 4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 GAO89087.1 - 1e-07 31.5 0.0 2.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 GAO89087.1 - 3.6e-06 25.8 0.1 7.5e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 GAO89087.1 - 0.0046 17.7 0.0 0.031 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAO89087.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAO89087.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 GAO89088.1 - 9.1e-11 41.4 13.4 0.00036 20.7 0.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89088.1 - 2.7e-07 30.4 15.9 0.0028 17.8 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 GAO89088.1 - 0.18 11.5 1.7 0.42 10.4 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger NolV PF06635.7 GAO89088.1 - 0.18 10.9 0.1 9.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein NolV zf-Di19 PF05605.7 GAO89088.1 - 0.21 11.7 7.0 2.5 8.3 1.2 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Kelch_5 PF13854.1 GAO89089.1 - 2.6e-13 49.5 0.1 2.6e-13 49.5 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 GAO89089.1 - 6.5e-08 32.5 1.3 2.9e-05 24.1 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 GAO89089.1 - 7.9e-07 28.7 10.8 0.0017 18.1 0.0 5.7 4 2 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO89089.1 - 0.053 13.7 10.0 0.91 9.8 0.1 4.8 5 1 1 6 6 6 0 Kelch motif Histone PF00125.19 GAO89090.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAO89090.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 GAO89090.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAO89090.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAO89090.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 GAO89090.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 GAO89091.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAO89091.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAO89091.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAO89091.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MFS_1 PF07690.11 GAO89092.1 - 4.8e-41 140.6 42.5 4.8e-41 140.6 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89092.1 - 1.5e-09 36.9 12.4 1.5e-09 36.9 8.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.7 GAO89093.1 - 2.3e-16 59.1 0.5 7e-16 57.6 0.4 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family Exo5 PF09810.4 GAO89094.1 - 5.1e-136 453.1 0.0 6.8e-136 452.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 GAO89094.1 - 4.5e-05 22.9 0.3 0.00035 20.0 0.0 2.5 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF3445 PF11927.3 GAO89095.1 - 2.6e-81 272.6 0.0 3.4e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 GAO89096.1 - 2.5e-83 280.4 19.4 3e-83 280.1 13.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 GAO89097.1 - 9.3e-47 158.3 3.1 1e-46 158.2 0.0 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PRP3 PF08572.5 GAO89098.1 - 3.2e-73 245.7 5.4 6.6e-73 244.7 3.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 GAO89098.1 - 4.3e-41 139.5 0.1 4.3e-41 139.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 GAO89099.1 - 1.1e-86 290.6 0.0 3.1e-86 289.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAO89099.1 - 1.7e-62 210.2 0.1 3.7e-62 209.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAO89099.1 - 1.9e-34 118.6 0.0 6e-33 113.8 0.0 3.0 2 1 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 GAO89099.1 - 6.8e-26 91.3 0.1 1.2e-19 70.8 0.0 3.1 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 GAO89099.1 - 4.9e-17 61.6 0.0 3.2e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 GAO89099.1 - 0.0006 17.8 15.8 0.0006 17.8 11.0 2.1 2 0 0 2 2 2 1 Nop14-like family DUF1227 PF06777.6 GAO89100.1 - 9.9e-63 210.2 0.4 2.5e-62 208.9 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 GAO89100.1 - 2.3e-52 176.8 0.2 4e-52 176.1 0.2 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 GAO89100.1 - 9.6e-45 152.5 0.0 2.1e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 GAO89100.1 - 0.00094 18.7 0.0 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 GAO89100.1 - 0.0019 17.0 0.0 0.013 14.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 GAO89100.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 GAO89100.1 - 0.0083 15.9 0.0 0.032 14.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAO89100.1 - 0.032 14.3 1.2 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Seryl_tRNA_N PF02403.17 GAO89100.1 - 7.4 6.6 8.2 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain zf-RING_2 PF13639.1 GAO89101.1 - 1.3e-07 31.3 8.2 2.8e-07 30.2 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAO89101.1 - 2.1e-07 30.9 2.1 4.7e-07 29.8 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 GAO89101.1 - 4.4e-05 23.3 6.2 0.00012 22.0 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 GAO89101.1 - 0.00014 21.6 2.4 0.00032 20.4 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 GAO89101.1 - 0.00031 20.3 9.6 0.00065 19.3 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 GAO89101.1 - 0.03 14.3 7.8 0.078 13.0 5.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 GAO89101.1 - 0.048 13.6 9.0 0.1 12.6 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 GAO89101.1 - 0.07 12.8 6.2 0.15 11.7 4.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RSF PF14876.1 GAO89101.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator zf-RING_4 PF14570.1 GAO89101.1 - 0.15 11.6 6.0 7.2 6.2 4.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 GAO89101.1 - 0.16 11.6 6.2 0.29 10.8 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAO89101.1 - 2.7 8.0 7.2 5.5 7.0 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 GAO89101.1 - 5 6.9 7.0 9.5 6.0 4.9 1.5 1 0 0 1 1 1 0 PHD-finger LCM PF04072.9 GAO89102.1 - 1.1e-21 77.2 0.0 4e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.8 GAO89103.1 - 8.7e-84 280.6 11.0 1.3e-83 280.0 7.7 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Med13_C PF06333.7 GAO89103.1 - 2.1 6.7 7.9 2.9 6.3 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal adh_short PF00106.20 GAO89104.1 - 7.7e-28 97.4 0.0 9.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89104.1 - 3.7e-20 72.7 0.0 5.2e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89104.1 - 1.4e-13 50.8 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO89104.1 - 3e-07 30.6 0.0 4.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAO89104.1 - 6.4e-07 28.8 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 GAO89104.1 - 0.00038 20.1 0.1 0.0009 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 GAO89104.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAO89104.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ist1 PF03398.9 GAO89105.1 - 2.7e-49 166.7 2.5 1.4e-24 86.3 2.1 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway Arylsulfotran_2 PF14269.1 GAO89106.1 - 6.4e-59 199.5 4.9 1e-58 198.8 3.0 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO89106.1 - 1.9e-19 69.5 3.5 2.7e-18 65.7 2.4 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 GAO89106.1 - 7.8e-17 61.0 32.5 7.8e-17 61.0 22.5 3.2 2 1 1 3 3 3 1 Major Facilitator Superfamily Toxin_R_bind_N PF07953.7 GAO89106.1 - 0.16 11.4 0.2 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Sulfotransfer_3 PF13469.1 GAO89107.1 - 0.00038 21.4 0.3 0.00057 20.8 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Clat_adaptor_s PF01217.15 GAO89108.1 - 2.7e-51 173.0 1.0 4.5e-51 172.3 0.7 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 GAO89108.1 - 1.6e-20 73.7 0.0 2.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PBP1_TM PF14812.1 GAO89108.1 - 1.7 9.0 4.2 3.4 8.0 2.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIID-18kDa PF02269.11 GAO89109.1 - 1.3e-29 101.8 0.3 8.9e-28 95.9 0.2 2.4 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit Pyridox_oxidase PF01243.15 GAO89110.1 - 5e-06 26.4 0.0 8.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1153 PF06627.6 GAO89110.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) zf-C2H2_jaz PF12171.3 GAO89111.1 - 2.1e-07 30.8 0.3 3.6e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO89111.1 - 6.4e-06 26.1 0.6 1.1e-05 25.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAO89111.1 - 0.006 16.8 0.6 0.012 15.9 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 GAO89111.1 - 0.14 12.3 0.2 0.35 10.9 0.1 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Cytidylate_kin2 PF13189.1 GAO89111.1 - 1.8 8.4 7.8 4 7.2 0.6 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family MAP7 PF05672.6 GAO89111.1 - 3.6 6.9 30.2 3.5 6.9 1.1 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family BIR PF00653.16 GAO89112.1 - 2.2e-42 143.3 6.0 1.3e-21 76.7 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain GIY-YIG PF01541.19 GAO89113.1 - 0.031 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Aminotran_1_2 PF00155.16 GAO89115.1 - 1.2e-62 211.9 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAO89115.1 - 0.036 12.3 0.0 0.066 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 GAO89115.1 - 0.069 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Allinase Mmp37 PF09139.6 GAO89116.1 - 2.2e-142 473.9 0.0 2.8e-142 473.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 RNA_pol_Rpb5_C PF01191.14 GAO89116.1 - 4.1e-34 116.0 0.6 9e-34 114.9 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 GAO89116.1 - 1.4e-31 108.7 0.0 3.4e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 GAO89116.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease APG6 PF04111.7 GAO89117.1 - 0.99 8.3 56.4 0.036 13.1 11.9 3.4 2 1 1 3 3 3 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 GAO89117.1 - 1.6 8.6 48.8 0.047 13.5 8.5 4.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 GAO89117.1 - 6.6 7.5 36.0 1.1 9.9 6.2 4.6 2 1 2 4 4 4 0 Occludin homology domain Baculo_PEP_C PF04513.7 GAO89117.1 - 8.2 6.2 20.5 1.4 8.7 0.5 3.8 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_2 PF02230.11 GAO89118.1 - 4.1e-16 59.0 0.0 1.1e-09 38.1 0.0 3.4 2 1 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAO89118.1 - 0.0017 18.3 1.2 0.0088 15.9 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAO89118.1 - 0.028 14.0 0.1 0.075 12.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold SDA1 PF05285.7 GAO89118.1 - 0.03 13.6 2.9 0.041 13.1 2.0 1.1 1 0 0 1 1 1 0 SDA1 Mannosyl_trans2 PF04188.8 GAO89119.1 - 6.6e-52 176.8 9.2 2.3e-37 128.9 4.3 3.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) CYSTM PF12734.2 GAO89120.1 - 0.012 15.6 36.4 0.012 15.6 25.2 5.8 1 1 2 3 3 3 0 Cysteine-rich TM module stress tolerance Pol_alpha_B_N PF08418.5 GAO89121.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_35 PF01301.14 GAO89122.1 - 4.3e-97 325.2 0.0 5.9e-97 324.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAO89122.1 - 1.7e-70 236.1 0.8 2.9e-70 235.3 0.6 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAO89122.1 - 3e-57 191.6 12.6 1.3e-32 112.2 1.6 3.6 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAO89122.1 - 2.9e-27 93.8 0.1 7.7e-27 92.5 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 GAO89122.1 - 0.0038 16.8 0.2 0.021 14.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain CARDB PF07705.6 GAO89122.1 - 0.022 14.8 0.8 6.6 6.8 0.0 3.1 3 0 0 3 3 3 0 CARDB Nol1_Nop2_Fmu PF01189.12 GAO89123.1 - 3.6e-29 102.0 0.0 9.5e-17 61.2 0.0 4.5 3 1 2 5 5 5 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 GAO89123.1 - 0.0065 16.4 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF1090 PF06476.7 GAO89123.1 - 0.089 12.4 0.6 0.21 11.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) FtsJ PF01728.14 GAO89123.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase 2HCT PF03390.10 GAO89123.1 - 0.44 8.8 0.1 0.66 8.2 0.0 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family PLAC8 PF04749.12 GAO89124.1 - 7.2e-26 90.8 16.2 8.5e-26 90.5 11.3 1.1 1 0 0 1 1 1 1 PLAC8 family Peptidase_M16 PF00675.15 GAO89125.1 - 2e-57 193.1 0.3 5.4e-57 191.7 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAO89125.1 - 7.5e-44 149.5 0.0 3.6e-41 140.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Epimerase PF01370.16 GAO89126.1 - 3e-22 79.1 0.0 4.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO89126.1 - 3.4e-11 42.3 0.0 4.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO89126.1 - 7.9e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO89126.1 - 4.3e-07 29.1 0.0 8.1e-05 21.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 GAO89126.1 - 1.1e-06 27.7 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAO89126.1 - 2.3e-06 27.6 0.1 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO89126.1 - 0.0052 16.4 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAO89126.1 - 0.025 14.3 0.0 0.065 13.0 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 GAO89126.1 - 0.037 14.3 0.1 0.085 13.1 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO89126.1 - 0.06 12.2 0.0 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fibrillarin PF01269.12 GAO89127.1 - 8.5e-108 358.5 0.0 1e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 GAO89127.1 - 2.1e-06 27.4 0.1 3.6e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 GAO89127.1 - 0.021 14.3 0.1 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 GAO89127.1 - 0.058 12.9 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.3 GAO89128.1 - 6.9e-51 172.7 1.2 8.9e-51 172.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 GAO89128.1 - 6.2e-35 118.8 1.7 6.2e-35 118.8 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) CASP_C PF08172.7 GAO89129.1 - 5.5e-93 310.5 3.8 5.5e-93 310.5 2.6 3.6 2 1 0 3 3 3 1 CASP C terminal Viral_P18 PF04521.8 GAO89129.1 - 0.025 14.0 0.4 0.025 14.0 0.3 4.4 4 1 0 5 5 5 0 ssRNA positive strand viral 18kD cysteine rich protein Tropomyosin_1 PF12718.2 GAO89129.1 - 0.42 10.4 54.4 3.3 7.5 2.9 5.4 4 1 1 5 5 5 0 Tropomyosin like Ion_trans_2 PF07885.11 GAO89130.1 - 4.7e-28 96.7 23.2 3.6e-14 52.2 4.1 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 GAO89130.1 - 2 7.6 15.9 1.1 8.4 3.8 2.7 2 1 0 2 2 2 0 Ion transport protein Vps39_2 PF10367.4 GAO89131.1 - 3e-07 30.5 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Dioxygenase_C PF00775.16 GAO89132.1 - 8.2e-52 175.1 0.0 1.2e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAO89132.1 - 2.4e-17 62.6 0.0 4.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAO89132.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF824 PF05688.6 GAO89132.1 - 0.16 11.6 0.5 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Zn_clus PF00172.13 GAO89133.1 - 0.022 14.6 9.7 0.048 13.5 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 GAO89133.1 - 2.3 7.9 7.2 0.23 11.2 1.8 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) LSM PF01423.17 GAO89134.1 - 4.8e-19 67.6 0.3 6.4e-19 67.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 GAO89134.1 - 0.023 15.1 7.0 0.045 14.1 4.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Fasciclin PF02469.17 GAO89135.1 - 3.8e-43 146.5 0.0 2.3e-23 82.6 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.20 GAO89136.1 - 9.6e-07 28.2 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89136.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.1 GAO89137.1 - 1e-10 40.9 0.0 2.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAO89137.1 - 1.7e-10 40.7 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain ABC2_membrane PF01061.19 GAO89138.1 - 3.7e-96 320.2 62.4 1.3e-50 171.4 16.4 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 GAO89138.1 - 6.2e-41 138.2 15.5 8.5e-37 124.9 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 GAO89138.1 - 7.8e-38 129.8 0.0 7.5e-18 65.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 GAO89138.1 - 1.2e-24 86.1 0.1 9e-24 83.3 0.1 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAO89138.1 - 1.4e-06 27.8 0.1 0.00039 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAO89138.1 - 2.2e-06 26.9 0.1 0.00018 20.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAO89138.1 - 0.00044 19.7 1.5 0.02 14.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO89138.1 - 0.00062 19.8 0.4 0.0043 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAO89138.1 - 0.0014 18.5 0.1 0.044 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAO89138.1 - 0.0017 17.6 0.0 0.39 9.9 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 GAO89138.1 - 0.0027 16.8 18.8 0.0027 16.8 13.0 3.5 3 1 0 3 3 3 1 ABC-2 family transporter protein cobW PF02492.14 GAO89138.1 - 0.0076 15.7 0.4 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAO89138.1 - 0.01 16.6 0.0 0.38 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 GAO89138.1 - 0.015 15.2 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAO89138.1 - 0.023 15.0 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO89138.1 - 0.024 14.7 0.4 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAO89138.1 - 0.027 14.1 1.4 3.1 7.4 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 GAO89138.1 - 0.095 13.1 0.0 21 5.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 GAO89138.1 - 0.17 11.2 1.9 50 3.1 0.1 3.7 2 1 1 3 3 3 0 AAA-like domain Hum_adeno_E3A PF05393.6 GAO89138.1 - 0.5 10.0 3.4 0.22 11.1 0.2 2.0 2 0 0 2 2 1 0 Human adenovirus early E3A glycoprotein adh_short PF00106.20 GAO89139.1 - 1.8e-27 96.2 1.6 1.9e-27 96.2 0.0 1.9 2 0 0 2 2 1 1 short chain dehydrogenase Ferric_reduct PF01794.14 GAO89139.1 - 6.7e-21 74.6 7.3 1.9e-20 73.2 5.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component adh_short_C2 PF13561.1 GAO89139.1 - 5.1e-15 55.8 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_6 PF08030.7 GAO89139.1 - 4.3e-13 49.4 0.0 3.6e-09 36.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO89139.1 - 2.6e-12 46.5 0.1 2.1e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain KR PF08659.5 GAO89139.1 - 8.7e-08 32.0 1.5 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAO89139.1 - 6.1e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO89139.1 - 0.0017 18.1 1.1 0.0043 16.8 0.8 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAO89139.1 - 0.0089 16.0 0.2 0.13 12.2 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_1 PF00175.16 GAO89139.1 - 0.024 15.2 0.0 0.081 13.4 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain THF_DHG_CYH_C PF02882.14 GAO89139.1 - 0.047 12.7 0.1 0.091 11.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_5 PF08323.6 GAO89139.1 - 0.092 12.2 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain ApbA PF02558.11 GAO89139.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 GAO89140.1 - 6.8e-14 51.3 0.0 3.9e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89140.1 - 6.3e-07 29.1 8.2 1.2e-06 28.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAO89141.1 - 7.4e-30 104.0 0.7 9.8e-30 103.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89141.1 - 2.7e-18 66.6 0.1 3.3e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89141.1 - 1.3e-12 47.7 0.5 2.4e-12 46.9 0.4 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO89141.1 - 2.2e-08 33.8 0.1 3.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO89141.1 - 2.5e-05 24.3 0.6 0.0001 22.3 0.4 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAO89141.1 - 0.0079 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO89141.1 - 0.01 14.7 0.5 0.087 11.7 0.4 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain ACT_7 PF13840.1 GAO89141.1 - 0.019 14.4 1.1 0.06 12.8 0.0 2.3 3 0 0 3 3 3 0 ACT domain Eno-Rase_NADH_b PF12242.3 GAO89141.1 - 0.033 13.9 0.2 0.1 12.4 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 GAO89141.1 - 0.043 13.4 0.1 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF3842 PF12953.2 GAO89141.1 - 0.06 13.4 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) ADH_N PF08240.7 GAO89142.1 - 1.3e-28 98.9 0.1 2.1e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO89142.1 - 3.2e-13 49.3 0.0 8.4e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 GAO89142.1 - 0.014 14.3 0.7 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase ApbA PF02558.11 GAO89142.1 - 0.018 14.4 0.1 0.05 13.0 0.1 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 GAO89142.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 GAO89142.1 - 0.048 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3956 PF13104.1 GAO89142.1 - 0.049 13.2 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) MtrD PF04207.7 GAO89142.1 - 1.5 8.1 6.0 0.18 11.1 0.3 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D 2-Hacid_dh_C PF02826.14 GAO89143.1 - 4.2e-55 185.6 0.0 6.8e-55 184.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.14 GAO89143.1 - 3.3e-35 120.1 0.0 6.5e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.25 GAO89143.1 - 7.2e-20 70.8 0.1 1.5e-19 69.8 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAO89143.1 - 0.00066 19.5 0.5 0.0024 17.7 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 GAO89143.1 - 0.067 13.6 0.1 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GAT PF03127.9 GAO89144.1 - 3.2e-14 52.7 0.0 9.6e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 GAO89144.1 - 0.00025 20.7 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 VHS domain DDE_Tnp_IS66 PF03050.9 GAO89144.1 - 0.025 13.7 1.5 0.047 12.9 1.0 1.4 1 0 0 1 1 1 0 Transposase IS66 family SapB_1 PF05184.10 GAO89144.1 - 0.051 13.4 0.1 7.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF2347 PF09804.4 GAO89144.1 - 0.071 12.3 1.4 0.17 11.1 1.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Chitin_bind_3 PF03067.10 GAO89145.1 - 3.6e-17 63.2 2.3 5.8e-17 62.5 1.6 1.3 1 0 0 1 1 1 1 Chitin binding domain Cation_efflux PF01545.16 GAO89146.1 - 7.7e-28 97.3 4.1 9.9e-28 97.0 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family Pectate_lyase_3 PF12708.2 GAO89147.1 - 1.2e-89 300.2 18.1 9.1e-70 235.2 7.8 2.7 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAO89147.1 - 3.6e-08 32.7 3.5 0.0057 16.0 0.2 3.2 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Fungal_trans PF04082.13 GAO89148.1 - 7.6e-13 47.9 1.6 1.4e-12 47.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 GAO89149.1 - 1.6e-17 63.5 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAO89149.1 - 0.013 14.0 0.1 0.36 9.3 0.0 2.3 3 0 0 3 3 3 0 Alanine-glyoxylate amino-transferase RNase_Zc3h12a PF11977.3 GAO89149.1 - 0.094 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Ank_2 PF12796.2 GAO89151.1 - 1.7e-56 188.5 1.6 2.1e-17 63.2 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAO89151.1 - 5.8e-52 171.0 10.2 1.5e-08 34.0 0.1 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 GAO89151.1 - 4.9e-41 134.6 4.3 6.2e-05 22.8 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAO89151.1 - 4.2e-40 135.4 9.9 1.5e-12 47.6 0.1 6.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO89151.1 - 2.7e-35 119.5 12.3 7e-08 32.4 0.1 7.7 2 2 6 8 8 8 7 Ankyrin repeats (many copies) CorA PF01544.13 GAO89151.1 - 2.7e-13 49.5 2.4 3e-13 49.4 0.1 2.2 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein GLE1 PF07817.8 GAO89151.1 - 0.037 12.9 0.3 0.07 12.0 0.2 1.4 1 0 0 1 1 1 0 GLE1-like protein DUF4604 PF15377.1 GAO89151.1 - 0.34 11.1 5.2 0.68 10.1 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Amidase PF01425.16 GAO89152.1 - 8e-84 282.0 0.0 1.1e-83 281.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Pyr_redox_2 PF07992.9 GAO89152.1 - 5.2e-27 95.0 0.0 1e-25 90.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO89152.1 - 1.7e-08 34.7 0.1 8.5e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAO89153.1 - 9.6e-29 100.4 2.0 1.6e-28 99.7 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89153.1 - 3e-25 89.4 0.0 3.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89153.1 - 1.1e-12 48.0 0.6 1.7e-12 47.4 0.4 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAO89153.1 - 0.024 14.4 2.4 0.95 9.2 0.2 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sod_Fe_N PF00081.17 GAO89154.1 - 4.7e-34 116.4 1.6 8.8e-34 115.6 1.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 GAO89154.1 - 2.2e-31 107.8 0.2 3.7e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Glyco_hydro_47 PF01532.15 GAO89155.1 - 5.8e-140 466.9 0.0 6.7e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 GAO89155.1 - 0.015 15.6 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Histidinol_dh PF00815.15 GAO89156.1 - 1.2e-174 580.8 6.7 1.2e-174 580.8 4.6 1.8 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 GAO89156.1 - 8.4e-25 86.2 0.1 4e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 GAO89156.1 - 8e-12 45.2 0.2 2.4e-11 43.7 0.2 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 GAO89156.1 - 0.016 15.1 1.0 0.047 13.6 0.1 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Ribosomal_60s PF00428.14 GAO89156.1 - 0.46 10.9 9.4 0.46 10.9 1.1 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Utp11 PF03998.8 GAO89157.1 - 1.7e-53 181.9 41.2 2e-53 181.7 28.6 1.1 1 0 0 1 1 1 1 Utp11 protein Hph PF13694.1 GAO89157.1 - 2.2 8.2 9.8 5 7.1 2.6 2.2 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Cmc1 PF08583.5 GAO89158.1 - 1.6e-17 63.0 4.0 1.6e-17 63.0 2.8 1.7 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 GAO89158.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 CHCH domain DUF3287 PF11690.3 GAO89158.1 - 0.31 11.1 6.5 0.35 10.9 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) TFIID-31kDa PF02291.10 GAO89159.1 - 9.7e-30 103.0 0.0 8.5e-24 83.7 0.0 2.5 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Mucin PF01456.12 GAO89159.1 - 0.23 11.2 12.5 0.54 10.0 8.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF605 PF04652.11 GAO89159.1 - 3.3 7.0 14.0 4.5 6.5 9.7 1.2 1 0 0 1 1 1 0 Vta1 like LNS2 PF08235.8 GAO89160.1 - 1.5e-70 235.7 0.0 2.5e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 GAO89160.1 - 2.3e-41 139.9 0.0 1.8e-40 137.0 0.0 2.2 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 GAO89160.1 - 0.0059 16.0 0.1 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 GAO89161.1 - 1.5e-06 28.2 0.1 5.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Macoilin PF09726.4 GAO89161.1 - 0.00052 18.4 22.3 0.00052 18.4 15.4 2.4 3 0 0 3 3 3 1 Transmembrane protein DUF3584 PF12128.3 GAO89161.1 - 0.79 6.9 44.6 0.085 10.1 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Thg1C PF14413.1 GAO89162.1 - 1.8e-54 182.6 0.8 2.3e-54 182.2 0.6 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 GAO89162.1 - 6.2e-46 155.3 0.0 9e-46 154.8 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 GAO89164.1 - 5.9e-15 54.5 0.2 0.00019 21.1 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 GAO89164.1 - 0.049 11.7 0.0 0.11 10.6 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Methyltransf_23 PF13489.1 GAO89165.1 - 6.6e-16 58.4 0.0 1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO89165.1 - 2.2e-07 31.2 0.0 6.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO89165.1 - 1.4e-06 28.7 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO89165.1 - 4.3e-06 27.2 0.0 7.1e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAO89165.1 - 8.6e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 GAO89165.1 - 0.00022 20.6 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAO89165.1 - 0.00035 20.1 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAO89165.1 - 0.0011 18.0 0.0 0.0033 16.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAO89165.1 - 0.0026 18.0 0.0 0.036 14.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain DUF1156 PF06634.7 GAO89165.1 - 0.015 14.9 0.1 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Methyltransf_26 PF13659.1 GAO89165.1 - 0.017 15.1 0.1 0.056 13.4 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAO89165.1 - 0.036 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 GAO89165.1 - 0.13 11.4 0.0 0.65 9.0 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family WD40 PF00400.27 GAO89166.1 - 2.9e-14 52.3 7.1 4.5e-08 32.6 0.2 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 GAO89166.1 - 0.00026 20.7 0.0 1.2 8.8 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAO89166.1 - 0.11 10.7 0.0 0.33 9.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Mesothelin PF06060.7 GAO89166.1 - 0.14 10.1 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) RNA_pol_Rpb1_1 PF04997.7 GAO89167.1 - 2.6e-122 408.2 0.0 4e-122 407.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAO89167.1 - 7.9e-105 350.0 0.1 1.5e-104 349.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAO89167.1 - 1.9e-71 239.4 0.0 4.4e-71 238.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 GAO89167.1 - 1e-64 217.7 0.4 2e-64 216.7 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 GAO89167.1 - 5.1e-47 159.5 0.0 1.2e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 GAO89167.1 - 4.1e-43 146.3 6.6 1.1e-42 144.9 4.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 GAO89167.1 - 3.1e-37 126.6 0.1 7.9e-37 125.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 GAO89167.1 - 2.6e-10 39.5 203.7 0.069 13.2 8.9 14.3 9 3 4 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat Sel1 PF08238.7 GAO89168.1 - 1.1e-43 146.6 49.0 1.6e-06 28.5 0.2 13.0 13 1 1 14 14 14 9 Sel1 repeat TPR_7 PF13176.1 GAO89168.1 - 0.0058 16.3 0.8 24 5.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF877 PF05943.7 GAO89168.1 - 0.0064 15.0 0.3 0.011 14.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF877) TPR_14 PF13428.1 GAO89168.1 - 0.029 15.0 2.2 4.1 8.3 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAO89168.1 - 0.43 11.3 17.2 1.4 9.7 0.2 6.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TBPIP PF07106.8 GAO89169.1 - 0.021 14.3 0.7 0.021 14.3 0.5 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snapin_Pallidin PF14712.1 GAO89169.1 - 0.053 13.8 0.4 0.12 12.6 0.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin IFP_35_N PF07334.8 GAO89169.1 - 0.091 12.7 0.8 0.31 11.0 0.6 2.0 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Phage_connect_1 PF05135.8 GAO89169.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Mei5 PF10376.4 GAO89169.1 - 0.12 11.8 19.5 1.7 8.1 13.4 2.7 1 1 0 1 1 1 0 Double-strand recombination repair protein Mut7-C PF01927.11 GAO89169.1 - 0.13 12.1 0.4 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF4140 PF13600.1 GAO89169.1 - 0.35 11.3 4.7 0.17 12.3 0.4 2.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.6 GAO89169.1 - 0.58 10.0 5.6 1.9 8.3 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) OmpH PF03938.9 GAO89169.1 - 4 7.3 8.9 32 4.4 6.2 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.11 GAO89170.1 - 4.7e-34 117.6 42.9 2.6e-31 108.6 19.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 GAO89170.1 - 6.6 6.7 8.8 65 3.5 0.0 3.9 3 1 0 3 3 3 0 YtpI-like protein Glyco_hydro_1 PF00232.13 GAO89171.1 - 2.4e-160 533.6 0.0 2.9e-160 533.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HD_assoc PF13286.1 GAO89171.1 - 0.14 12.4 0.4 9.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Kelch_5 PF13854.1 GAO89172.1 - 5.9e-28 96.3 0.1 2e-07 30.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAO89172.1 - 1.8e-27 94.8 6.2 1.1e-08 34.6 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO89172.1 - 3.4e-24 83.9 0.7 0.00015 21.8 0.0 5.6 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAO89172.1 - 7.8e-24 83.2 4.5 1.6e-07 31.3 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 GAO89172.1 - 9.2e-21 72.7 0.5 5.9e-06 25.8 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 GAO89172.1 - 5.4e-20 70.6 0.1 1.9e-06 27.2 0.0 4.9 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 GAO89172.1 - 7.1e-09 35.6 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 GAO89172.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 GAO89173.1 - 4.6e-23 80.1 19.7 1.4e-07 31.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAO89173.1 - 3.6e-05 23.5 0.2 0.0032 17.1 0.1 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAO89173.1 - 0.077 12.5 0.0 4 7.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.8 GAO89174.1 - 1.4e-104 350.9 6.1 1.6e-104 350.7 4.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 GAO89174.1 - 7.3 4.6 34.1 12 4.0 23.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 GAO89175.1 - 3e-05 24.0 10.1 0.057 13.7 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO89175.1 - 0.00084 19.4 1.6 0.053 13.6 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAO89175.1 - 0.0081 16.4 17.5 0.062 13.6 1.1 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO89175.1 - 0.01 16.1 0.4 0.01 16.1 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 GAO89175.1 - 0.037 13.6 0.4 0.064 12.9 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Dus PF01207.12 GAO89176.1 - 3.5e-41 141.0 0.0 1.2e-27 96.6 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 GAO89176.1 - 0.054 13.1 0.3 0.054 13.1 0.2 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 GAO89177.1 - 7.6e-62 208.1 1.1 1.7e-61 207.0 0.0 1.8 2 0 0 2 2 2 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 GAO89177.1 - 0.021 14.5 0.2 0.057 13.1 0.0 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 GAO89177.1 - 0.15 10.7 0.1 0.26 9.9 0.1 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.10 GAO89177.1 - 0.23 10.9 1.5 2.5 7.6 0.0 2.9 4 0 0 4 4 4 0 Septum formation initiator DUF1385 PF07136.6 GAO89177.1 - 0.41 9.6 3.0 0.28 10.1 1.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DUF2404 PF10296.4 GAO89178.1 - 0.00075 19.5 0.0 0.0072 16.4 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Pkinase PF00069.20 GAO89180.1 - 4e-64 216.2 0.0 6.8e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89180.1 - 1.4e-35 122.6 0.0 1.6e-30 106.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO89180.1 - 3.5e-05 22.9 0.0 0.027 13.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 GAO89180.1 - 0.00064 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAO89180.1 - 0.0012 18.6 0.4 0.0061 16.3 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAO89180.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO89180.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Senescence PF06911.7 GAO89181.1 - 4.1e-47 160.1 8.7 6.1e-47 159.6 6.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein Metallophos PF00149.23 GAO89182.1 - 2.9e-07 30.0 0.7 6.4e-07 28.9 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FIST PF08495.5 GAO89182.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 FIST N domain Acyl-CoA_dh_1 PF00441.19 GAO89183.1 - 1.3e-40 138.9 8.2 2e-40 138.3 5.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAO89183.1 - 3.1e-28 98.6 2.2 1.8e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAO89183.1 - 5.1e-19 67.5 0.0 1.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAO89183.1 - 7.6e-16 58.5 5.5 1.4e-15 57.6 3.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAO89183.1 - 0.021 14.2 0.1 0.08 12.3 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal bZIP_1 PF00170.16 GAO89184.1 - 2.2e-05 24.2 11.6 0.00013 21.8 8.0 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO89184.1 - 0.0011 18.7 16.0 0.0071 16.1 9.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 GAO89184.1 - 0.0063 16.7 3.9 0.0082 16.4 2.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF904) HALZ PF02183.13 GAO89184.1 - 0.042 13.5 1.1 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3395 PF11875.3 GAO89184.1 - 0.047 13.3 1.3 0.076 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) SlyX PF04102.7 GAO89184.1 - 0.053 13.8 3.0 0.094 13.1 0.7 2.4 2 1 0 2 2 2 0 SlyX Calici_MSP PF05752.6 GAO89184.1 - 0.053 13.1 0.6 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF972 PF06156.8 GAO89184.1 - 0.066 13.5 2.2 0.11 12.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAO89184.1 - 0.077 12.4 5.7 0.38 10.2 3.7 2.1 1 1 0 1 1 1 0 Septum formation initiator Allexi_40kDa PF05549.6 GAO89184.1 - 0.14 11.4 0.8 0.21 10.8 0.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Guanylate_kin PF00625.16 GAO89184.1 - 0.17 11.3 1.8 0.27 10.6 1.2 1.3 1 0 0 1 1 1 0 Guanylate kinase IncA PF04156.9 GAO89184.1 - 0.2 11.2 4.1 0.33 10.5 2.8 1.3 1 0 0 1 1 1 0 IncA protein Cauli_AT PF03233.8 GAO89184.1 - 0.29 10.8 1.1 0.51 10.0 0.8 1.3 1 0 0 1 1 1 0 Aphid transmission protein DP PF08781.5 GAO89184.1 - 0.33 10.6 5.0 0.54 9.9 3.5 1.3 1 0 0 1 1 1 0 Transcription factor DP EAP30 PF04157.11 GAO89184.1 - 0.74 8.9 4.6 0.57 9.3 2.3 1.5 2 0 0 2 2 2 0 EAP30/Vps36 family DUF2937 PF11157.3 GAO89184.1 - 1 8.6 4.3 1.9 7.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FlxA PF14282.1 GAO89184.1 - 1 9.3 11.3 4.1 7.4 6.7 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 GAO89184.1 - 9.3 5.1 10.7 13 4.5 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GWT1 PF06423.7 GAO89185.1 - 1.2e-43 148.5 3.9 1.2e-43 148.5 2.7 2.2 2 0 0 2 2 2 1 GWT1 Amidase PF01425.16 GAO89186.1 - 2e-84 284.0 0.1 2.6e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Amidase PDEase_II PF02112.10 GAO89187.1 - 2.8e-51 174.4 0.0 1.1e-25 90.2 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAO89187.1 - 3.2e-06 26.8 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAO89187.1 - 0.0072 16.0 3.5 0.021 14.4 2.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4246 PF14033.1 GAO89188.1 - 9.9e-92 308.1 1.3 7e-39 133.7 0.0 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF4246) SPRY PF00622.23 GAO89189.1 - 1.8e-19 70.0 0.0 2.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Peptidase_M24 PF00557.19 GAO89190.1 - 6.7e-60 202.2 0.0 9.3e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAO89190.1 - 7.4e-26 90.1 0.0 1.4e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sec63 PF02889.11 GAO89192.1 - 7.7e-51 173.1 0.0 2e-49 168.5 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 GAO89192.1 - 3.5e-18 65.0 0.5 7.8e-18 63.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 GAO89192.1 - 0.023 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ALO PF04030.9 GAO89194.1 - 3.5e-91 305.3 0.9 4.9e-91 304.8 0.6 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 GAO89194.1 - 1.4e-33 115.3 0.0 2.1e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 GAO89195.1 - 7.3e-162 539.3 26.7 7.3e-162 539.3 18.5 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 GAO89195.1 - 1.3e-14 53.6 0.0 1.4e-05 24.6 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat Ppx-GppA PF02541.11 GAO89195.1 - 0.31 10.1 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Arf PF00025.16 GAO89196.1 - 1.6e-64 216.3 1.4 1.8e-64 216.2 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAO89196.1 - 2.1e-12 46.4 4.0 2e-06 26.7 0.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 GAO89196.1 - 5.9e-11 42.0 0.0 6.8e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAO89196.1 - 6.3e-10 38.5 0.0 7.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAO89196.1 - 5.4e-08 32.8 0.0 6.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO89196.1 - 1.7e-07 31.7 0.0 2.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAO89196.1 - 3.7e-07 29.5 0.0 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAO89196.1 - 8.8e-07 28.5 0.0 8.9e-05 21.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.12 GAO89196.1 - 0.0049 15.3 0.0 0.0056 15.1 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 AAA_17 PF13207.1 GAO89196.1 - 0.0075 17.0 0.2 0.01 16.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 GAO89196.1 - 0.058 12.6 0.3 0.16 11.2 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.13 GAO89196.1 - 0.088 11.8 0.1 0.22 10.5 0.0 1.6 1 1 1 2 2 2 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 GAO89196.1 - 0.098 12.5 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAO89196.1 - 0.11 12.0 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 GAO89196.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 GAO89197.1 - 5.1e-44 149.7 0.1 1.6e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89197.1 - 5.9e-26 90.1 0.0 3.6e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAO89197.1 - 5.1e-06 25.1 0.0 5.1e-06 25.1 0.0 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) HMGL-like PF00682.14 GAO89198.1 - 2.7e-65 220.3 0.0 4.1e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 GAO89198.1 - 4.6e-21 75.0 0.0 9.7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AMP-binding PF00501.23 GAO89199.1 - 5e-59 199.7 2.4 2e-22 79.1 0.0 4.7 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 GAO89199.1 - 9.9e-11 42.2 0.0 2.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 GAO89199.1 - 0.0023 17.7 0.5 0.0048 16.6 0.4 1.5 1 0 0 1 1 1 1 Gas vesicle protein G DUF4032 PF13224.1 GAO89199.1 - 0.15 11.7 0.4 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) SDA1 PF05285.7 GAO89200.1 - 2e-95 319.8 35.3 2e-95 319.8 24.5 2.2 2 0 0 2 2 2 1 SDA1 Ribosomal_S7 PF00177.16 GAO89200.1 - 1.5e-39 134.9 1.2 4.7e-39 133.3 0.8 1.9 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NUC130_3NT PF08158.7 GAO89200.1 - 2.7e-23 81.9 0.2 7.6e-23 80.5 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.5 GAO89201.1 - 2.7e-28 98.7 0.3 7.1e-28 97.4 0.1 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Strep_his_triad PF04270.8 GAO89201.1 - 0.0045 16.6 0.9 1.1 8.9 0.1 2.5 2 0 0 2 2 2 2 Streptococcal histidine triad protein HSP70 PF00012.15 GAO89202.1 - 5.1e-63 212.9 11.3 3.6e-60 203.5 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Tubulin_3 PF14881.1 GAO89203.1 - 2.1e-87 291.2 0.1 3e-87 290.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAO89203.1 - 5.8e-43 145.6 0.1 1.9e-42 143.9 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 GAO89203.1 - 6.4e-06 26.1 0.0 0.083 12.6 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ssu72 PF04722.8 GAO89204.1 - 0.062 12.6 1.2 4 6.7 0.1 2.3 2 0 0 2 2 2 0 Ssu72-like protein DUF87 PF01935.12 GAO89204.1 - 0.38 10.5 5.5 7.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2347 PF09804.4 GAO89205.1 - 5.8e-107 357.1 0.0 7.8e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 GAO89205.1 - 5.5e-69 231.7 0.4 8.2e-69 231.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 GAO89205.1 - 0.0049 15.3 0.0 3.4 6.0 0.0 2.6 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 GAO89205.1 - 0.017 14.8 0.0 0.051 13.2 0.0 1.8 1 1 0 1 1 1 0 Stabilization of polarity axis SNF2_N PF00176.18 GAO89207.1 - 4.3e-64 216.1 0.0 6.4e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO89207.1 - 4e-11 42.6 0.0 9.8e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89207.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_C13 PF01650.13 GAO89208.1 - 8.4e-41 139.9 0.1 1.1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.22 GAO89209.1 - 1.5e-45 152.8 9.3 1.7e-16 59.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha-amylase PF00128.19 GAO89210.1 - 6.2e-24 84.9 0.0 1.2e-23 84.0 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 GAO89210.1 - 2.1e-05 22.5 0.1 0.067 10.9 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 GAO89210.1 - 0.073 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) 4HBT_3 PF13622.1 GAO89211.1 - 2.4e-44 151.9 2.3 4e-44 151.2 1.6 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAO89211.1 - 2.6e-23 82.0 0.0 1.7e-12 47.1 0.0 4.2 3 1 0 3 3 3 3 Acyl-CoA thioesterase GtrA PF04138.9 GAO89211.1 - 0.00092 19.1 2.9 0.077 12.9 1.0 2.4 2 0 0 2 2 2 2 GtrA-like protein Tad PF13400.1 GAO89211.1 - 5.5 7.1 6.8 5 7.2 0.1 2.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3445 PF11927.3 GAO89212.1 - 6e-80 268.2 0.1 7.5e-80 267.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HSP70 PF00012.15 GAO89213.1 - 5.5e-11 41.1 0.4 2.1e-09 35.8 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 GAO89213.1 - 0.016 14.8 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 GAO89213.1 - 0.064 11.8 0.1 0.22 10.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.7 GAO89214.1 - 1.5e-92 309.4 0.0 1.9e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAO89214.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO89214.1 - 0.069 13.6 0.0 0.32 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAO89214.1 - 0.078 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 GAO89215.1 - 2e-25 89.1 0.0 3.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89215.1 - 6.7e-05 22.7 15.0 6.7e-05 22.7 10.4 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 GAO89216.1 - 1e-23 83.0 6.1 1.3e-23 82.7 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 GAO89216.1 - 0.019 14.4 5.6 0.024 14.0 3.9 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2164 PF09932.4 GAO89216.1 - 0.022 14.5 0.1 0.059 13.1 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) PEP-utilisers_N PF05524.8 GAO89216.1 - 0.047 13.4 2.4 0.069 12.9 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal eIF-4B PF06273.6 GAO89216.1 - 0.048 12.4 3.7 0.057 12.1 2.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B AAA_23 PF13476.1 GAO89216.1 - 0.06 13.6 5.7 0.072 13.4 4.0 1.1 1 0 0 1 1 1 0 AAA domain Fibrillarin_2 PF10113.4 GAO89216.1 - 0.087 11.1 0.0 0.099 10.9 0.0 1.0 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Baculo_PEP_C PF04513.7 GAO89216.1 - 0.19 11.5 1.4 0.37 10.5 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAO89216.1 - 0.43 10.3 2.1 3.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 GAO89216.1 - 0.5 10.6 2.5 21 5.4 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 GAO89216.1 - 0.5 9.5 11.1 4.3 6.4 5.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 GAO89216.1 - 0.66 9.6 8.2 6 6.4 4.4 2.0 2 0 0 2 2 2 0 Mnd1 family PilJ PF13675.1 GAO89216.1 - 0.72 10.1 3.7 3.5 7.9 0.7 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc24 PF08286.6 GAO89216.1 - 1.9 8.2 8.8 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.6 GAO89216.1 - 1.9 8.9 7.6 3.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 GAO89216.1 - 3.5 7.6 5.7 2.4 8.0 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Rabaptin PF03528.10 GAO89216.1 - 4.6 7.2 13.3 5.9 6.8 6.7 2.0 2 0 0 2 2 2 0 Rabaptin DivIC PF04977.10 GAO89216.1 - 4.8 6.7 11.9 11 5.6 4.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Bap31 PF05529.7 GAO89216.1 - 5.7 6.3 6.8 34 3.8 3.2 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Lipoprotein_20 PF13942.1 GAO89216.1 - 5.7 6.4 9.0 14 5.1 3.8 2.0 2 0 0 2 2 2 0 YfhG lipoprotein ATG27 PF09451.5 GAO89217.1 - 2.2e-92 309.1 1.4 6e-92 307.6 1.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 GAO89217.1 - 2.3e-05 24.1 0.0 0.0018 18.0 0.0 2.7 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat AAA_2 PF07724.9 GAO89219.1 - 1.4e-45 155.2 0.0 5.4e-44 150.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAO89219.1 - 6.9e-28 97.4 0.0 2.4e-15 56.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAO89219.1 - 7.7e-25 86.6 3.1 8.2e-25 86.5 0.4 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 GAO89219.1 - 1.3e-15 57.3 0.0 2e-09 37.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO89219.1 - 1.4e-15 57.7 10.3 6.2e-06 26.3 0.0 6.0 3 2 2 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 GAO89219.1 - 4e-15 56.1 0.3 4.5e-05 23.6 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 GAO89219.1 - 6.4e-09 35.5 0.0 3.4e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 GAO89219.1 - 4.2e-08 34.0 6.7 0.0096 16.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAO89219.1 - 2.4e-07 30.3 0.0 0.027 13.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 GAO89219.1 - 3.8e-07 30.0 0.0 0.041 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAO89219.1 - 4.1e-07 30.3 4.0 0.0057 16.9 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_19 PF13245.1 GAO89219.1 - 8.5e-07 28.6 1.7 0.016 14.9 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Clp_N PF02861.15 GAO89219.1 - 1.1e-06 28.4 2.1 0.0028 17.5 0.0 4.0 3 0 0 3 3 3 1 Clp amino terminal domain Mg_chelatase PF01078.16 GAO89219.1 - 1.5e-05 24.2 0.0 0.14 11.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAO89219.1 - 2e-05 24.5 1.4 0.27 11.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 GAO89219.1 - 4.8e-05 23.1 10.1 0.01 15.5 0.1 4.7 5 1 1 6 6 4 2 Archaeal ATPase AAA_33 PF13671.1 GAO89219.1 - 5.1e-05 23.1 0.0 0.19 11.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 GAO89219.1 - 6.4e-05 23.0 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 GAO89219.1 - 0.0001 21.3 0.0 0.0059 15.5 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 GAO89219.1 - 0.00017 21.3 0.0 0.87 9.2 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAO89219.1 - 0.00018 21.7 0.6 0.76 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_3 PF07726.6 GAO89219.1 - 0.0002 20.9 0.0 0.77 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAO89219.1 - 0.00035 20.0 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAO89219.1 - 0.00046 19.6 1.2 2.3 7.5 0.0 3.8 3 1 0 4 4 4 2 AAA domain DUF258 PF03193.11 GAO89219.1 - 0.00083 18.5 0.0 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 GAO89219.1 - 0.0018 18.0 0.2 0.15 11.7 0.0 3.3 2 1 1 3 3 3 1 NTPase ResIII PF04851.10 GAO89219.1 - 0.002 18.0 0.0 0.42 10.4 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 GAO89219.1 - 0.0035 16.9 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAO89219.1 - 0.004 16.8 0.0 0.41 10.2 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_10 PF12846.2 GAO89219.1 - 0.0043 16.5 3.8 0.34 10.3 0.0 4.2 4 2 0 5 5 5 1 AAA-like domain Torsin PF06309.6 GAO89219.1 - 0.01 15.7 0.0 0.071 12.9 0.0 2.3 3 0 0 3 3 2 0 Torsin AAA_21 PF13304.1 GAO89219.1 - 0.016 15.1 0.0 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAO89219.1 - 0.026 13.9 0.0 5.9 6.2 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 GAO89219.1 - 0.039 13.9 0.0 0.78 9.7 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 GAO89219.1 - 0.047 13.3 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Peptidase_M16 PF00675.15 GAO89219.1 - 0.2 11.3 3.3 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) IncA PF04156.9 GAO89219.1 - 0.52 9.8 7.6 1.6 8.3 5.3 1.8 1 0 0 1 1 1 0 IncA protein AMPKBI PF04739.10 GAO89219.1 - 0.86 9.4 2.4 3.7 7.4 1.7 2.0 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Macoilin PF09726.4 GAO89219.1 - 1.6 6.9 7.3 2.5 6.2 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 GAO89219.1 - 4.4 6.2 7.4 9.2 5.2 5.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 GAO89219.1 - 4.5 7.5 19.1 1.1 9.4 0.1 4.3 3 2 0 3 3 2 0 AAA domain adh_short PF00106.20 GAO89220.1 - 4.1e-17 62.6 0.0 3e-15 56.5 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.16 GAO89220.1 - 1.5e-16 60.1 0.0 3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase adh_short_C2 PF13561.1 GAO89220.1 - 6.3e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89220.1 - 1.3e-07 31.4 0.0 9.5e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 KR domain DUF2334 PF10096.4 GAO89220.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF360 PF04020.8 GAO89221.1 - 0.086 13.1 0.8 0.086 13.1 0.5 2.6 3 0 0 3 3 3 0 Membrane protein of unknown function PAP2 PF01569.16 GAO89221.1 - 0.33 10.6 10.5 2.7 7.6 1.1 2.9 2 1 0 2 2 2 0 PAP2 superfamily DUF106 PF01956.11 GAO89221.1 - 0.61 9.6 6.6 4.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Integral membrane protein DUF106 AA_permease_2 PF13520.1 GAO89222.1 - 3.6e-48 164.1 50.2 4.5e-48 163.8 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO89222.1 - 2.1e-16 59.3 43.8 3e-16 58.8 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.3 GAO89222.1 - 0.41 10.3 9.2 0.14 11.8 2.6 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CDC45 PF02724.9 GAO89223.1 - 2.7e-250 831.7 5.6 4.1e-249 827.8 3.9 2.9 1 1 0 1 1 1 1 CDC45-like protein Zip PF02535.17 GAO89223.1 - 1.3 7.9 3.4 1.5 7.7 0.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Nop14 PF04147.7 GAO89223.1 - 2.9 5.6 30.1 0.23 9.3 8.5 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 GAO89223.1 - 3.8 6.4 39.0 4.1 6.3 7.1 2.2 2 0 0 2 2 2 0 BUD22 CBM_4_9 PF02018.12 GAO89224.1 - 0.048 13.6 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain DUF1537 PF07005.6 GAO89225.1 - 3.8e-32 111.7 1.3 3.8e-32 111.7 0.9 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 Glu_syn_central PF04898.9 GAO89225.1 - 0.13 11.5 0.0 0.33 10.1 0.1 1.6 2 0 0 2 2 2 0 Glutamate synthase central domain PAP_central PF04928.12 GAO89226.1 - 4.4e-107 356.6 0.0 5.7e-107 356.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 GAO89226.1 - 1.4e-51 174.1 0.0 2.6e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 GAO89226.1 - 1.3e-09 38.2 0.0 4.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 GAO89226.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 Nrap PF03813.9 GAO89226.1 - 0.12 9.8 0.0 0.18 9.2 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Abhydrolase_1 PF00561.15 GAO89227.1 - 1.3e-14 54.3 0.1 1.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO89227.1 - 3.5e-11 43.4 0.0 5.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO89227.1 - 0.0018 17.5 0.0 0.1 11.8 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO89227.1 - 0.0067 16.1 0.1 0.27 10.9 0.1 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 GAO89228.1 - 1.4e-23 83.1 0.2 1.3e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Flavin_Reduct PF01613.13 GAO89228.1 - 1.1e-16 61.0 0.0 3.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Flavin reductase like domain DUF1014 PF06244.7 GAO89230.1 - 3.3e-23 82.2 15.7 1.1e-22 80.5 10.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) WD40 PF00400.27 GAO89231.1 - 8.3e-27 92.0 21.6 2.2e-08 33.6 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 GAO89232.1 - 4e-34 118.1 0.0 7.7e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 GAO89232.1 - 2.1e-07 30.7 5.8 3.9e-07 29.9 4.0 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 GAO89232.1 - 0.00022 20.6 0.0 0.00072 18.9 0.0 1.9 1 0 0 1 1 1 1 CUE domain DinI PF06183.8 GAO89232.1 - 0.14 12.2 0.1 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 DinI-like family LysM PF01476.15 GAO89233.1 - 1e-18 66.9 0.0 3.5e-08 33.2 0.0 3.3 3 0 0 3 3 3 3 LysM domain WavE PF07507.6 GAO89233.1 - 0.11 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Como_LCP PF02247.11 GAO89233.1 - 0.37 9.1 1.6 20 3.4 0.0 2.8 2 1 0 3 3 3 0 Large coat protein Abhydrolase_3 PF07859.8 GAO89234.1 - 1.8e-31 109.3 0.0 3.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Alpha-amylase PF00128.19 GAO89234.1 - 8.6e-16 58.2 1.0 7.1e-14 51.9 0.7 2.9 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 GAO89234.1 - 1.6e-14 53.9 0.1 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 GAO89234.1 - 1.9e-08 34.5 0.0 5.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAO89234.1 - 6.1e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_18 PF00704.23 GAO89235.1 - 6.5e-81 272.4 5.8 1.4e-80 271.3 4.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAO89236.1 - 8.7e-27 92.7 9.5 2.7e-07 30.3 0.0 5.7 5 0 0 5 5 5 5 LysM domain F-box-like PF12937.2 GAO89238.1 - 2.2e-05 24.0 0.5 6.5e-05 22.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO89238.1 - 0.0068 16.0 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF4291 PF14124.1 GAO89239.1 - 1.9e-78 262.2 1.0 2.1e-78 262.1 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Adenylsucc_synt PF00709.16 GAO89240.1 - 3.7e-154 513.4 0.0 4.2e-154 513.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 GAO89241.1 - 4.9e-22 77.4 1.2 9.8e-22 76.4 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 GAO89242.1 - 6.2e-29 100.6 0.0 1.2e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89242.1 - 1.6e-08 34.2 11.3 2.6e-08 33.6 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 GAO89242.1 - 0.0036 16.7 1.3 0.0036 16.7 0.9 3.0 3 1 0 3 3 3 1 Vta1 like MFS_1 PF07690.11 GAO89243.1 - 3.1e-34 118.2 18.0 5.4e-29 101.0 0.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89243.1 - 1.7e-10 40.0 6.0 3.4e-10 39.0 4.2 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAO89243.1 - 0.00029 19.3 7.2 0.00029 19.3 5.0 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein GTP1_OBG PF01018.17 GAO89244.1 - 1.4e-38 132.0 3.3 7.9e-30 103.5 2.1 2.6 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 GAO89244.1 - 3e-21 75.5 0.0 5.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO89244.1 - 1.2e-08 34.4 0.1 2.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 GAO89244.1 - 0.0048 15.7 0.1 0.33 9.7 0.0 2.6 3 0 0 3 3 3 1 ArgK protein ABC_tran PF00005.22 GAO89244.1 - 0.013 15.8 1.7 0.028 14.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 GAO89244.1 - 0.017 14.9 0.0 0.91 9.3 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Miro PF08477.8 GAO89244.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 GAO89244.1 - 0.049 13.0 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 GAO89244.1 - 0.11 12.1 0.1 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAO89244.1 - 0.17 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.1 GAO89245.1 - 4.1e-34 118.2 0.0 1.2e-33 116.7 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAO89245.1 - 9.7e-07 28.3 0.0 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 GAO89245.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Zn_clus PF00172.13 GAO89246.1 - 3.5e-07 30.0 9.3 7.6e-07 28.9 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAO89247.1 - 9.8e-08 32.0 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO89247.1 - 2.2e-05 24.2 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 GAO89247.1 - 0.011 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase AHS2 PF02626.10 GAO89248.1 - 1.4e-66 224.5 0.0 8e-48 163.0 0.0 2.3 2 0 0 2 2 2 2 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 GAO89248.1 - 1e-55 188.3 0.0 1.9e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAO89248.1 - 2.7e-39 133.6 0.2 6.7e-39 132.4 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAO89248.1 - 3.1e-32 110.7 0.0 6e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 GAO89248.1 - 4.8e-30 104.5 0.0 9.3e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 GAO89248.1 - 2.4e-14 53.5 0.0 4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAO89248.1 - 1.4e-10 40.6 1.0 1.5e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAO89248.1 - 9.6e-09 34.4 0.0 1.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAO89248.1 - 1.4e-06 27.8 0.0 2.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAO89248.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAO89248.1 - 0.0026 17.2 0.0 0.0091 15.4 0.0 1.9 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 GAO89248.1 - 0.0054 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAO89248.1 - 0.11 12.2 3.0 6.5 6.4 0.1 3.5 2 1 1 3 3 3 0 Biotin-lipoyl like LamB_YcsF PF03746.11 GAO89249.1 - 3.1e-71 239.2 0.0 3.7e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Homeobox_KN PF05920.6 GAO89250.1 - 4.2e-18 64.7 0.6 1.1e-17 63.3 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAO89250.1 - 4e-05 23.1 0.2 0.00011 21.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 GAO89250.1 - 0.0015 18.7 23.7 0.0044 17.2 0.9 5.1 4 1 1 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89250.1 - 0.0028 17.8 1.9 0.0028 17.8 1.3 5.1 4 1 0 4 4 4 2 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.11 GAO89250.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain AAA_13 PF13166.1 GAO89250.1 - 0.85 8.0 2.4 12 4.2 0.5 2.1 1 1 1 2 2 2 0 AAA domain zf-H2C2_2 PF13465.1 GAO89250.1 - 4.8 7.6 9.9 6.1 7.3 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain UQ_con PF00179.21 GAO89251.1 - 2.3e-10 40.0 0.0 4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAO89251.1 - 0.026 14.3 0.1 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain BRE PF06113.7 GAO89251.1 - 0.11 11.5 0.1 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Maf PF02545.9 GAO89252.1 - 3e-48 163.5 0.0 3.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein CybS PF05328.7 GAO89253.1 - 1e-48 164.3 0.0 1.2e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 GAO89253.1 - 0.026 14.3 0.6 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ADH_zinc_N PF00107.21 GAO89254.1 - 5.8e-23 80.8 0.0 8.6e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO89254.1 - 2.5e-06 28.4 0.0 4.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAO89254.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF3335 PF11814.3 GAO89254.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C39 like family DEAD PF00270.24 GAO89255.1 - 1.2e-43 148.5 0.4 3.5e-43 147.0 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89255.1 - 2.4e-19 68.9 0.4 6.4e-19 67.6 0.3 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89255.1 - 0.00093 19.0 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 GAO89255.1 - 0.013 14.7 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain PhoH PF02562.11 GAO89255.1 - 0.027 13.7 0.1 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein HEM4 PF02602.10 GAO89255.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Luciferase_N PF05295.6 GAO89255.1 - 0.1 12.4 0.1 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain HLH PF00010.21 GAO89256.1 - 3e-08 33.2 0.0 5.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRCC PF10253.4 GAO89256.1 - 0.04 14.6 2.4 0.044 14.4 1.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CAF-1_p150 PF11600.3 GAO89256.1 - 0.3 10.4 5.1 0.44 9.8 3.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 GAO89256.1 - 0.35 9.1 3.0 0.36 9.0 2.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Hamartin PF04388.7 GAO89256.1 - 0.37 9.4 3.7 0.36 9.4 2.5 1.0 1 0 0 1 1 1 0 Hamartin protein GFA PF04828.9 GAO89257.1 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1631 PF07793.6 GAO89257.1 - 0.044 11.9 0.0 0.045 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-ribbon_3 PF13248.1 GAO89257.1 - 0.12 11.6 0.4 0.24 10.6 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAO89257.1 - 0.15 11.5 0.8 0.32 10.5 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2890 PF11081.3 GAO89257.1 - 1.9 8.4 7.2 0.15 12.1 1.2 1.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2890) Cu-oxidase_3 PF07732.10 GAO89259.1 - 3.9e-34 116.9 0.0 1.1e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO89259.1 - 4.9e-32 110.3 1.5 1e-24 86.5 0.0 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO89259.1 - 3e-16 59.7 0.0 5.3e-15 55.6 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase Fungal_trans_2 PF11951.3 GAO89260.1 - 1.4e-10 40.3 0.2 5.6e-10 38.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89260.1 - 2.4e-08 33.7 9.5 6.6e-08 32.3 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1757 PF08560.5 GAO89260.1 - 0.077 12.6 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1757) bZIP_2 PF07716.10 GAO89260.1 - 1.7 8.5 8.0 3.1 7.7 5.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper VWA_2 PF13519.1 GAO89261.1 - 3.5e-07 30.4 0.1 5.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAO89261.1 - 9.4e-05 22.3 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 GAO89261.1 - 0.00013 21.7 0.0 0.00054 19.7 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Apc4 PF12896.2 GAO89263.1 - 2e-68 229.8 1.9 3e-68 229.2 1.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 GAO89263.1 - 1.3e-18 66.2 0.0 4.8e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 GAO89263.1 - 0.00031 20.5 0.0 0.016 15.0 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT PF02985.17 GAO89264.1 - 1.7e-13 49.3 7.9 0.0012 18.7 0.0 9.5 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 GAO89264.1 - 1.4e-12 47.6 12.3 1.8e-08 34.6 0.0 8.5 8 2 2 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.1 GAO89264.1 - 5e-10 39.5 10.0 5e-05 23.5 0.0 7.1 3 3 4 7 7 7 2 HEAT repeats IBN_N PF03810.14 GAO89264.1 - 2.3e-07 30.6 0.3 2.8e-06 27.1 0.0 3.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 GAO89264.1 - 3.5e-06 26.5 4.2 0.013 14.8 0.0 5.1 4 2 1 6 6 6 2 CLASP N terminal DUF3385 PF11865.3 GAO89264.1 - 0.0037 17.2 0.1 3.5 7.5 0.2 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Dopey_N PF04118.9 GAO89264.1 - 0.0063 15.3 0.4 1.2 7.8 0.1 2.6 2 0 0 2 2 2 2 Dopey, N-terminal Arm PF00514.18 GAO89264.1 - 0.0097 15.7 1.6 14 5.6 0.1 4.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 GAO89264.1 - 0.044 13.7 0.1 0.84 9.6 0.1 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion SelB-wing_2 PF09106.6 GAO89265.1 - 0.069 13.0 3.3 0.46 10.4 0.6 2.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix Ribosomal_S8 PF00410.14 GAO89266.1 - 3.7e-24 85.0 0.0 5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 GAO89267.1 - 1.1e-18 67.8 0.0 1.4e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PS_Dcarbxylase PF02666.10 GAO89269.1 - 1.4e-90 301.9 0.0 3e-89 297.6 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase APC10 PF03256.11 GAO89270.1 - 1.2e-42 145.7 0.0 9e-42 142.8 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Iso_dh PF00180.15 GAO89271.1 - 8.2e-130 432.7 0.0 9.3e-130 432.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.16 GAO89272.1 - 1.7e-16 60.3 7.3 2.1e-16 60.0 4.4 1.7 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.16 GAO89273.1 - 2.4e-36 125.4 0.0 6.5e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAO89273.1 - 1.7e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SinI PF08671.5 GAO89273.1 - 0.17 11.3 0.8 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Anti-repressor SinI RRM_1 PF00076.17 GAO89275.1 - 6.8e-42 140.9 1.0 1.1e-19 69.7 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO89275.1 - 9.1e-33 112.0 0.2 1.1e-17 63.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAO89275.1 - 4.3e-30 103.8 0.3 1e-29 102.5 0.2 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 GAO89275.1 - 1.8e-20 72.5 0.0 2.7e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAO89275.1 - 0.0064 16.3 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif MIP-T3 PF10243.4 GAO89275.1 - 0.4 9.0 24.3 0.63 8.4 16.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 GAO89276.1 - 6.4e-21 73.9 0.5 1e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 GAO89276.1 - 9.7e-10 38.8 21.7 3.7e-09 36.9 14.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 GAO89276.1 - 0.02 14.9 0.2 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region ATP_synt_I PF03899.10 GAO89276.1 - 0.031 14.4 3.4 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 ATP synthase I chain COX14 PF14880.1 GAO89276.1 - 0.063 12.9 1.5 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly OMPdecase PF00215.19 GAO89277.1 - 3.7e-10 39.5 0.0 2.3e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.13 GAO89279.1 - 4.5e-26 91.2 0.1 7.9e-26 90.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Adap_comp_sub PF00928.16 GAO89280.1 - 1.1e-17 64.0 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAO89280.1 - 1.2e-07 31.5 0.1 2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 GAO89280.1 - 0.0034 16.5 0.0 0.045 12.9 0.0 2.1 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.6 GAO89280.1 - 0.01 15.9 0.2 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 GAO89281.1 - 4.5e-10 39.1 0.3 1.1e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 GAO89282.1 - 1.1e-104 349.6 10.0 1.3e-104 349.3 7.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 GAO89282.1 - 4.5e-07 30.0 2.7 4.5e-07 30.0 1.9 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAO89282.1 - 2.7e-05 24.2 5.9 2.7e-05 24.2 4.1 3.0 2 1 0 3 3 3 2 EamA-like transporter family DUF2937 PF11157.3 GAO89282.1 - 0.24 10.7 0.7 0.61 9.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Acyl_transf_3 PF01757.17 GAO89282.1 - 0.65 8.7 17.8 10 4.8 10.3 2.2 1 1 1 2 2 2 0 Acyltransferase family Syja_N PF02383.13 GAO89283.1 - 1.3e-100 336.3 0.0 1.8e-100 335.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 GAO89283.1 - 1.4e-37 127.5 0.0 2.6e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT PF02985.17 GAO89284.1 - 3.3e-31 104.5 14.7 7.6e-06 25.5 0.0 11.5 13 0 0 13 13 12 6 HEAT repeat HEAT_EZ PF13513.1 GAO89284.1 - 4.8e-30 103.2 10.6 1.5e-13 50.7 0.0 11.5 8 2 4 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.1 GAO89284.1 - 3.7e-24 84.8 0.9 2.1e-08 34.3 0.0 8.2 3 3 5 8 8 8 6 HEAT repeats Cnd1 PF12717.2 GAO89284.1 - 6.3e-11 42.4 1.0 0.0041 16.9 0.0 6.9 6 3 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAO89284.1 - 1.2e-09 38.4 0.0 0.1 13.0 0.0 6.2 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 GAO89284.1 - 2.3e-09 36.1 0.3 0.00042 18.7 0.0 3.2 2 1 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 GAO89284.1 - 6.8e-09 35.2 0.5 0.22 11.3 0.0 6.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 GAO89284.1 - 9.9e-08 31.6 0.0 1.6 8.0 0.0 7.0 5 2 2 7 7 7 1 CLASP N terminal MMS19_C PF12460.3 GAO89284.1 - 2.2e-07 29.9 0.0 0.034 12.8 0.0 4.6 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 GAO89284.1 - 6.7e-06 25.8 0.0 0.04 13.6 0.0 4.1 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 GAO89284.1 - 2.7e-05 24.1 1.4 0.032 14.1 0.0 5.0 4 2 1 5 5 5 1 Exportin 1-like protein Ipi1_N PF12333.3 GAO89284.1 - 0.0037 17.2 0.4 28 4.7 0.0 5.7 6 2 2 8 8 8 0 Rix1 complex component involved in 60S ribosome maturation HEAT_PBS PF03130.11 GAO89284.1 - 0.0052 17.1 1.2 11 6.7 0.0 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Sec7_N PF12783.2 GAO89284.1 - 0.02 14.3 0.7 0.58 9.5 0.0 3.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.5 GAO89284.1 - 0.036 13.6 0.0 20 4.7 0.0 3.8 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF4042 PF13251.1 GAO89284.1 - 0.099 12.1 0.5 29 4.0 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) IBN_N PF03810.14 GAO89284.1 - 0.27 11.1 1.0 16 5.5 0.0 4.3 4 1 1 5 5 5 0 Importin-beta N-terminal domain Zn_clus PF00172.13 GAO89285.1 - 2.7e-08 33.5 12.9 5.1e-08 32.6 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO89285.1 - 2.5e-07 29.6 2.6 3.6e-07 29.1 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 GAO89286.1 - 2e-71 239.5 0.0 2.5e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Choline_kinase PF01633.15 GAO89287.1 - 1.7e-62 210.7 0.1 4.1e-61 206.2 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 GAO89287.1 - 1.2e-15 56.6 0.2 7.5e-15 54.1 0.0 2.2 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 GAO89287.1 - 1.5e-08 34.7 0.0 3.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CesT PF05932.8 GAO89287.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family BCS1_N PF08740.6 GAO89287.1 - 0.033 13.8 0.1 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 BCS1 N terminal Phosphoesterase PF04185.9 GAO89288.1 - 2.3e-63 214.6 1.0 3.1e-63 214.2 0.7 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 GAO89289.1 - 2.5e-37 127.2 1.5 3.8e-35 120.1 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAO89289.1 - 4.1e-34 117.0 4.9 3e-32 111.0 0.4 3.3 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 GAO89289.1 - 3.5e-09 36.7 0.1 5.6e-06 26.3 0.0 3.7 3 1 0 3 3 3 1 Multicopper oxidase HAUS5 PF14817.1 GAO89289.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Mem_trans PF03547.13 GAO89290.1 - 1.9e-54 184.4 0.3 2.5e-54 184.0 0.2 1.2 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 GAO89291.1 - 2.1e-51 174.5 0.0 1.6e-48 165.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89291.1 - 3.8e-32 111.3 0.0 3.5e-31 108.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO89291.1 - 0.0016 17.4 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAO89291.1 - 0.0021 16.9 0.1 0.0034 16.2 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 GAO89291.1 - 0.074 11.8 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1263 PF06882.7 GAO89291.1 - 0.086 12.4 0.7 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Pyr_redox_2 PF07992.9 GAO89292.1 - 5.3e-36 124.3 1.1 9e-36 123.6 0.8 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAO89292.1 - 1.9e-32 111.5 0.1 4.2e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 GAO89292.1 - 1.6e-14 54.0 0.7 4.6e-14 52.5 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO89292.1 - 4.2e-05 23.6 0.0 9e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAO89292.1 - 0.0021 17.7 0.6 0.0021 17.7 0.4 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 GAO89292.1 - 0.0022 16.9 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 GAO89292.1 - 0.068 12.2 0.5 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAO89292.1 - 0.73 8.6 7.2 1.9 7.2 1.6 2.9 2 1 0 2 2 2 0 Glucose inhibited division protein A AIG1 PF04548.11 GAO89294.1 - 1.8e-08 33.7 0.0 2.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAO89294.1 - 7.2e-08 32.3 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAO89294.1 - 0.00063 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAO89294.1 - 0.00069 19.4 0.8 0.83 9.4 0.2 2.8 2 1 1 3 3 3 2 Dynamin family DUF815 PF05673.8 GAO89294.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAO89294.1 - 0.015 15.6 0.4 0.64 10.3 0.2 2.3 1 1 1 2 2 2 0 ABC transporter Miro PF08477.8 GAO89294.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 GAO89294.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 GAO89294.1 - 0.039 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 GAO89294.1 - 0.045 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 GAO89294.1 - 0.1 11.6 0.1 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 GAO89294.1 - 0.11 11.9 0.1 0.35 10.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 GAO89294.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit adh_short PF00106.20 GAO89295.1 - 4.8e-06 26.5 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO89295.1 - 0.0074 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Lipase_bact_N PF12262.3 GAO89298.1 - 0.014 14.6 0.2 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence factor lipase N-terminal Aldedh PF00171.17 GAO89299.1 - 1.8e-21 76.0 0.0 2e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_16 PF00722.16 GAO89300.1 - 7.5e-44 149.2 2.3 7.5e-44 149.2 1.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2884 PF11101.3 GAO89301.1 - 0.11 11.8 0.3 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) tRNA-synt_2b PF00587.20 GAO89302.1 - 3.6e-49 166.6 0.0 5.5e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAO89302.1 - 6.9e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Luciferase_cat PF10285.4 GAO89302.1 - 0.02 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain INT_SG_DDX_CT_C PF15300.1 GAO89302.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Fungal_trans PF04082.13 GAO89303.1 - 1.2e-25 89.8 0.4 1.2e-25 89.8 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO89304.1 - 2.1e-80 270.5 18.5 2.4e-80 270.3 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89304.1 - 2.3e-17 62.7 22.7 2.3e-17 62.7 15.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidohydro_2 PF04909.9 GAO89305.1 - 5.3e-20 72.0 0.0 6.3e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DIL PF01843.14 GAO89306.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 DIL domain Glyco_hydro_31 PF01055.21 GAO89307.1 - 4.2e-172 572.9 2.4 5.3e-172 572.6 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO89307.1 - 9.8e-12 44.5 0.7 4.3e-11 42.4 0.5 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like ADH_N PF08240.7 GAO89308.1 - 1.7e-27 95.3 0.8 1.7e-27 95.3 0.6 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO89308.1 - 5.7e-12 45.3 0.0 2.8e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ATP-synt_G PF04718.10 GAO89309.1 - 8e-33 113.1 0.1 2.2e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 GAO89310.1 - 3.5e-27 94.9 0.1 1.2e-25 90.0 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89310.1 - 2.8e-23 81.5 0.0 2.2e-22 78.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89310.1 - 0.00011 22.1 0.0 0.00011 22.1 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Methyltransf_16 PF10294.4 GAO89312.1 - 1.6e-21 76.5 0.0 2.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAO89312.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAO89312.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.7 GAO89313.1 - 8.7e-60 201.5 0.0 1.1e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.8 GAO89314.1 - 2.6e-122 407.3 0.0 4.9e-122 406.4 0.0 1.5 1 0 0 1 1 1 1 Noc2p family TrkH PF02386.11 GAO89315.1 - 1.5e-83 280.2 13.9 3.2e-81 272.6 3.0 2.0 2 0 0 2 2 2 2 Cation transport protein MoaC PF01967.16 GAO89318.1 - 7.7e-47 158.3 0.6 1.3e-46 157.6 0.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 GAO89319.1 - 3e-36 123.9 0.1 2e-35 121.2 0.0 2.1 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAO89319.1 - 8.7e-23 81.3 0.0 1.4e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAO89319.1 - 3e-05 24.1 0.0 0.0001 22.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAO89319.1 - 0.00021 21.2 0.0 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Sugar_tr PF00083.19 GAO89320.1 - 4e-75 253.1 28.7 4.8e-75 252.8 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89320.1 - 2.2e-23 82.5 46.6 6.6e-22 77.7 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2613 PF11021.3 GAO89320.1 - 0.11 12.1 0.1 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Glyco_hydro_1 PF00232.13 GAO89321.1 - 5.1e-150 499.6 0.0 6.2e-150 499.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 GAO89321.1 - 0.00025 20.5 0.0 0.00052 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans PF04082.13 GAO89322.1 - 4.7e-12 45.3 0.4 4.3e-11 42.1 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89322.1 - 1.9e-07 30.8 10.5 3.6e-07 29.9 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 GAO89325.1 - 1.1e-42 145.5 0.9 5e-23 81.9 0.1 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAO89325.1 - 8.9e-19 68.5 1.5 0.00017 21.6 0.3 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAO89325.1 - 1.2e-10 41.0 2.9 0.028 13.6 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 GAO89325.1 - 1.2e-08 34.7 3.0 1.2e-08 34.7 2.1 2.5 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 GAO89325.1 - 4.1e-08 32.6 0.5 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAO89325.1 - 5.7e-08 33.6 0.1 0.0049 17.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 GAO89325.1 - 6.4e-07 29.3 0.0 0.049 13.5 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 GAO89325.1 - 6.2e-06 26.3 0.7 0.14 12.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 GAO89325.1 - 8.8e-06 26.2 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 GAO89325.1 - 3.3e-05 23.1 0.1 0.051 12.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAO89325.1 - 3.7e-05 23.8 1.6 0.11 12.4 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 GAO89325.1 - 5.9e-05 22.9 2.4 0.47 10.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 GAO89325.1 - 8.6e-05 22.2 0.0 0.44 10.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAO89325.1 - 9.9e-05 22.6 0.0 0.62 10.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 GAO89325.1 - 0.00014 20.7 0.6 0.12 11.1 0.1 2.3 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 GAO89325.1 - 0.00028 20.8 0.4 0.088 12.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 GAO89325.1 - 0.001 18.9 0.2 1.7 8.4 0.0 3.1 2 1 0 2 2 2 2 Dynamin family AAA_5 PF07728.9 GAO89325.1 - 0.0012 18.5 0.3 0.22 11.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAO89325.1 - 0.0028 17.5 0.1 4.7 7.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 GAO89325.1 - 0.0033 16.8 0.0 0.43 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvA_C PF07499.8 GAO89325.1 - 0.004 17.2 0.0 2.3 8.4 0.0 2.9 2 0 0 2 2 2 1 RuvA, C-terminal domain NTPase_1 PF03266.10 GAO89325.1 - 0.0041 16.8 0.3 13 5.4 0.0 4.0 4 0 0 4 4 3 0 NTPase NACHT PF05729.7 GAO89325.1 - 0.0042 16.7 1.4 0.48 10.0 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA PF00004.24 GAO89325.1 - 0.0046 17.1 0.0 0.9 9.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAO89325.1 - 0.0061 16.7 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.1 GAO89325.1 - 0.01 14.9 0.1 4.1 6.3 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain DUF815 PF05673.8 GAO89325.1 - 0.011 14.6 0.1 1.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 GAO89325.1 - 0.015 15.0 3.9 2.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 GAO89325.1 - 0.019 14.4 0.4 5.4 6.3 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 GAO89325.1 - 0.02 14.5 0.4 3.9 7.1 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase cobW PF02492.14 GAO89325.1 - 0.06 12.7 0.5 5.1 6.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAO89325.1 - 0.075 12.4 2.4 1.8 7.9 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 GAO89325.1 - 0.1 12.1 0.1 27 4.1 0.0 3.2 3 1 1 4 4 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 GAO89325.1 - 0.14 12.4 17.2 0.53 10.5 0.0 3.7 4 1 0 4 4 2 0 AAA domain AAA_13 PF13166.1 GAO89325.1 - 0.59 8.5 10.1 0.98 7.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain Mt_ATP-synt_D PF05873.7 GAO89325.1 - 3.6 7.2 6.0 1.5 8.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2146 PF10220.4 GAO89326.1 - 0.59 8.0 5.4 0.58 8.0 3.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Myc_target_1 PF15179.1 GAO89326.1 - 1.9 8.0 7.9 2.2 7.8 5.5 1.0 1 0 0 1 1 1 0 Myc target protein 1 Lactamase_B_2 PF12706.2 GAO89327.1 - 1.1e-31 109.8 0.0 2.3e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 GAO89327.1 - 5.9e-24 83.3 0.1 1.2e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease bZIP_1 PF00170.16 GAO89327.1 - 2.9e-07 30.3 11.0 2.9e-07 30.3 7.6 2.7 2 0 0 2 2 2 1 bZIP transcription factor Lactamase_B PF00753.22 GAO89327.1 - 8.8e-06 25.5 0.0 1.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_2 PF07716.10 GAO89327.1 - 0.00039 20.1 10.1 0.00039 20.1 7.0 3.1 2 0 0 2 2 2 1 Basic region leucine zipper His_Phos_2 PF00328.17 GAO89328.1 - 7.8e-09 35.3 0.0 2.6e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 GAO89329.1 - 2.1e-22 79.7 0.0 3.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89329.1 - 3.6e-13 49.8 0.0 5.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89329.1 - 3e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAO89329.1 - 0.00018 21.5 0.0 0.00044 20.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAO89329.1 - 0.0021 17.2 0.1 0.051 12.7 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAO89329.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RuBisCO_small PF00101.15 GAO89329.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Gtr1_RagA PF04670.7 GAO89330.1 - 4.7e-71 238.6 0.2 1.3e-70 237.2 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 GAO89330.1 - 8.6e-05 21.8 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAO89330.1 - 0.00087 19.7 0.0 0.0042 17.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 GAO89330.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 GAO89330.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Cyt-b5 PF00173.23 GAO89331.1 - 1.3e-09 37.7 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.10 GAO89331.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Ribosomal_S25 PF03297.10 GAO89332.1 - 2.6e-36 123.8 5.9 2.8e-36 123.7 4.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 GAO89332.1 - 0.0083 15.6 0.2 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 GAO89332.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.4 1 1 0 1 1 1 0 MarR family Rrf2 PF02082.15 GAO89332.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.7 GAO89332.1 - 0.022 14.3 0.2 0.037 13.6 0.2 1.5 1 1 0 1 1 1 0 HTH domain FeoC PF09012.5 GAO89332.1 - 0.023 14.3 0.7 0.067 12.8 0.0 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator TrmB PF01978.14 GAO89332.1 - 0.047 13.3 0.1 0.076 12.7 0.1 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_42 PF06224.7 GAO89332.1 - 0.067 12.5 0.1 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 GAO89332.1 - 0.073 12.4 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding WD40 PF00400.27 GAO89333.1 - 3.6e-05 23.4 3.8 1.7 8.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Dus PF01207.12 GAO89334.1 - 6.3e-58 196.0 0.0 9.9e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 GAO89334.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CENP-X PF09415.5 GAO89335.1 - 1.9e-28 98.0 0.0 4.8e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 CENP-S associating Centromere protein X MIF PF01187.13 GAO89335.1 - 3.6e-09 36.7 0.0 6.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.16 GAO89335.1 - 5.9e-09 35.8 0.1 2.3e-07 30.7 0.1 2.6 1 1 0 1 1 1 1 Macro domain CBFD_NFYB_HMF PF00808.18 GAO89335.1 - 0.029 14.4 0.0 0.089 12.8 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Macoilin PF09726.4 GAO89335.1 - 2.7 6.1 10.7 3.7 5.6 7.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.5 GAO89335.1 - 5.3 5.3 5.4 9 4.5 3.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mis12 PF05859.7 GAO89336.1 - 2.3e-43 147.4 0.0 4.3e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein TMF_DNA_bd PF12329.3 GAO89336.1 - 0.0053 16.5 1.7 0.0077 16.0 0.3 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding PGC7_Stella PF15549.1 GAO89336.1 - 0.059 13.3 1.6 0.097 12.6 0.8 1.6 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain Spt20 PF12090.3 GAO89337.1 - 3.1e-53 179.8 0.1 3.1e-53 179.8 0.1 4.8 4 1 0 4 4 4 1 Spt20 family zf-C2H2 PF00096.21 GAO89338.1 - 9e-08 32.0 12.4 0.0007 19.7 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO89338.1 - 1.4e-05 25.1 4.3 1.4e-05 25.1 3.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO89338.1 - 6.8e-05 22.9 10.6 0.0034 17.5 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Acetyltransf_1 PF00583.19 GAO89339.1 - 3.2e-16 59.1 0.0 5.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO89339.1 - 9.6e-10 38.6 0.0 1.1e-09 38.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO89339.1 - 2.2e-06 27.3 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAO89339.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAO89339.1 - 1.8e-05 24.7 0.0 2e-05 24.5 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAO89339.1 - 4.8e-05 23.2 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO89339.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 GAO89339.1 - 0.00075 19.4 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO89339.1 - 0.0047 17.0 0.0 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuclease_T2 PF00445.13 GAO89340.1 - 3e-48 163.9 0.9 4.6e-48 163.3 0.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Imm27 PF15573.1 GAO89340.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 27 DUF1792 PF08759.6 GAO89340.1 - 0.023 14.2 0.2 0.034 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Apo-CIII PF05778.7 GAO89340.1 - 0.19 11.1 0.9 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Tissue_fac PF01108.12 GAO89340.1 - 1.2 8.8 3.8 4.6 7.0 0.1 2.3 1 1 1 2 2 2 0 Tissue factor BCNT PF07572.7 GAO89341.1 - 8.8e-29 99.2 1.0 8.8e-29 99.2 0.7 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development Fungal_trans PF04082.13 GAO89342.1 - 3.3e-25 88.4 0.1 8.6e-25 87.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prp19 PF08606.6 GAO89342.1 - 0.043 13.5 0.6 8.2 6.2 0.0 3.4 2 1 1 3 3 3 0 Prp19/Pso4-like adh_short PF00106.20 GAO89343.1 - 6.9e-20 71.6 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89343.1 - 3.4e-07 30.2 0.0 4.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89343.1 - 6.6e-07 29.1 0.0 1.4e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAO89343.1 - 0.024 14.6 0.3 0.083 12.8 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAO89343.1 - 0.06 13.1 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO89343.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DSBA PF01323.15 GAO89344.1 - 3.2e-21 75.7 0.0 3.6e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain VirB8 PF04335.8 GAO89345.1 - 1.7 8.1 3.9 21 4.6 0.0 2.6 2 1 1 3 3 3 0 VirB8 protein Peroxin-22 PF12827.2 GAO89346.1 - 0.072 12.8 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family Hexapep PF00132.19 GAO89347.1 - 4e-09 35.5 3.1 0.00078 18.8 0.2 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAO89347.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 GAO89347.1 - 0.059 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.7 GAO89347.1 - 0.065 11.7 0.1 0.097 11.2 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 GAO89347.1 - 4.6 6.8 6.5 7.4 6.2 0.2 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.11 GAO89350.1 - 9e-39 133.1 23.1 1.4e-38 132.5 16.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89350.1 - 2.3e-12 46.2 17.7 3.2e-12 45.7 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sensor PF13796.1 GAO89350.1 - 0.018 14.6 0.0 0.018 14.6 0.0 3.3 1 1 2 3 3 3 0 Putative sensor Glyco_hydro_35 PF01301.14 GAO89351.1 - 5e-77 259.3 2.9 1.1e-76 258.2 2.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAO89351.1 - 9.3e-72 240.2 2.9 1.2e-71 239.8 1.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAO89351.1 - 1.5e-49 166.8 8.1 2.4e-24 85.7 0.1 3.7 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAO89351.1 - 1.5e-28 98.0 0.1 3.5e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 AF1Q PF15017.1 GAO89351.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator ELO PF01151.13 GAO89352.1 - 5.2e-89 297.8 2.7 6.2e-89 297.5 1.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LCD1 PF09798.4 GAO89353.1 - 0.44 8.4 1.2 0.65 7.9 0.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SKG6 PF08693.5 GAO89354.1 - 6.4e-07 28.5 0.3 1.4e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 GAO89354.1 - 0.00029 20.5 1.0 0.00049 19.8 0.7 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 GAO89354.1 - 0.00057 19.4 0.0 0.0009 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM51 PF15345.1 GAO89354.1 - 0.0031 17.2 0.9 0.0055 16.4 0.2 1.6 1 1 0 1 1 1 1 Transmembrane protein 51 Alpha_GJ PF03229.8 GAO89354.1 - 0.016 15.4 3.6 0.034 14.4 2.5 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Plasmodium_Vir PF05795.6 GAO89354.1 - 0.031 13.4 0.6 0.041 13.0 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3188 PF11384.3 GAO89354.1 - 0.079 12.5 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) CcmD PF04995.9 GAO89354.1 - 0.088 12.5 0.4 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TruD PF01142.13 GAO89355.1 - 2.8e-52 177.6 0.0 8.4e-50 169.5 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF2293 PF10056.4 GAO89357.1 - 1.7e-32 111.1 1.7 1.7e-32 111.1 1.2 2.4 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2293) Mtc PF03820.12 GAO89359.1 - 3.7e-107 357.5 0.2 6e-107 356.8 0.1 1.3 1 1 0 1 1 1 1 Tricarboxylate carrier Acetyltransf_3 PF13302.1 GAO89360.1 - 2e-31 109.0 0.0 8.3e-31 107.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO89360.1 - 0.00013 21.8 0.1 0.23 11.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Serglycin PF04360.7 GAO89360.1 - 0.002 17.8 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Serglycin Acetyltransf_7 PF13508.1 GAO89360.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO89360.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.1 GAO89360.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidase PF01425.16 GAO89361.1 - 2.3e-93 313.4 0.1 3e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 GAO89362.1 - 1.3e-55 188.3 0.0 2.1e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89362.1 - 9.5e-20 70.7 0.0 1.4e-18 66.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase TAF4 PF05236.9 GAO89363.1 - 7.5e-18 64.7 1.6 1.6e-05 24.3 0.6 3.3 3 0 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family Pex14_N PF04695.8 GAO89363.1 - 0.019 14.9 0.3 0.019 14.9 0.2 5.1 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF73-100_C PF11718.3 GAO89364.1 - 1.3e-79 266.5 0.0 1.1e-75 253.6 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 GAO89364.1 - 3.8e-32 110.8 0.0 7.6e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 GAO89364.1 - 2.3e-18 66.5 0.1 4.1e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO89364.1 - 2.9e-11 43.2 0.4 5.7e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAO89364.1 - 4.6e-07 29.5 0.2 9e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 GAO89364.1 - 0.00019 21.1 0.1 0.00065 19.4 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.16 GAO89365.1 - 9.6e-88 294.2 0.0 1.2e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DEDD_Tnp_IS110 PF01548.12 GAO89365.1 - 0.085 12.5 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Transposase SRP19 PF01922.12 GAO89366.1 - 4.8e-31 107.2 0.0 7e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.13 GAO89367.1 - 1.2e-15 57.0 0.2 2.4e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89367.1 - 5.4e-11 42.2 9.5 8.6e-11 41.5 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AcylCoA_dehyd_C PF12186.3 GAO89367.1 - 0.03 14.1 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal TCTP PF00838.12 GAO89368.1 - 4.2e-48 163.4 0.4 4.8e-48 163.2 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Cullin PF00888.17 GAO89368.1 - 0.14 10.6 0.1 0.55 8.6 0.0 1.8 1 1 0 1 1 1 0 Cullin family FA_hydroxylase PF04116.8 GAO89369.1 - 2.4e-17 63.3 14.3 2.4e-17 63.3 9.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UBA_2 PF08587.6 GAO89371.1 - 0.00024 21.2 0.1 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) DUF3089 PF11288.3 GAO89371.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) ABC_tran PF00005.22 GAO89372.1 - 4.3e-49 166.3 0.1 2e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO89372.1 - 5.6e-32 111.2 34.5 3.6e-18 65.9 8.3 4.1 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO89372.1 - 5.8e-11 42.0 2.5 0.02 14.1 0.6 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO89372.1 - 1.2e-08 35.2 3.0 0.079 12.9 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 GAO89372.1 - 9.5e-07 28.4 0.1 0.016 14.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 GAO89372.1 - 4.6e-06 26.5 0.4 0.3 11.0 0.0 3.8 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAO89372.1 - 7.7e-06 26.3 0.8 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAO89372.1 - 3.9e-05 23.0 2.1 0.13 11.8 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAO89372.1 - 4.4e-05 22.5 0.9 0.24 10.2 0.0 2.9 2 1 1 3 3 3 2 Type II/IV secretion system protein Dynamin_N PF00350.18 GAO89372.1 - 0.00041 20.2 0.6 0.015 15.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 GAO89372.1 - 0.00043 19.8 0.0 0.18 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 GAO89372.1 - 0.00046 19.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 GAO89372.1 - 0.0013 17.9 0.2 0.12 11.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 GAO89372.1 - 0.0026 18.2 0.4 1.1 9.7 0.0 3.2 3 0 0 3 3 2 1 Miro-like protein Viral_helicase1 PF01443.13 GAO89372.1 - 0.0061 16.1 0.0 0.63 9.5 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.1 GAO89372.1 - 0.0073 16.1 0.1 2.1 8.3 0.0 3.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 GAO89372.1 - 0.0079 15.9 1.3 1.4 8.6 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 GAO89372.1 - 0.0089 15.1 0.6 2.8 7.0 0.0 2.5 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 GAO89372.1 - 0.0093 15.9 2.3 2.7 7.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 GAO89372.1 - 0.0094 15.0 0.5 0.92 8.5 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin AAA_18 PF13238.1 GAO89372.1 - 0.013 15.8 0.7 3.2 8.0 0.5 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAO89372.1 - 0.017 14.9 3.9 0.35 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 GAO89372.1 - 0.062 11.9 0.1 0.17 10.4 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_22 PF13401.1 GAO89372.1 - 0.069 13.2 3.3 9.6 6.3 0.0 3.5 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAO89372.1 - 0.15 12.8 5.3 1.5 9.6 0.5 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO89372.1 - 0.22 11.3 1.4 20 5.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAO89372.1 - 0.27 10.8 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Pox_A32 PF04665.7 GAO89372.1 - 1.5 8.0 7.5 8.2 5.6 0.1 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein Trypsin_2 PF13365.1 GAO89373.1 - 6.2e-05 22.9 0.0 0.0002 21.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 GAO89373.1 - 2.3 7.1 5.9 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 EF-hand_7 PF13499.1 GAO89374.1 - 1.3e-07 31.6 0.3 4.3e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAO89374.1 - 1.9e-06 26.7 0.0 0.013 14.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 GAO89374.1 - 3e-06 26.3 0.6 0.052 12.8 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 GAO89374.1 - 0.0007 19.1 0.5 1.2 8.8 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 GAO89374.1 - 0.001 18.7 0.6 0.14 12.1 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 GAO89374.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF896 PF05979.7 GAO89374.1 - 0.076 12.6 0.6 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Glyco_hydro_3 PF00933.16 GAO89375.1 - 8.9e-71 238.2 0.0 1.4e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO89375.1 - 1.8e-45 155.2 0.0 2.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO89375.1 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PS_Dcarbxylase PF02666.10 GAO89376.1 - 3.1e-47 160.5 0.1 3.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DEAD PF00270.24 GAO89377.1 - 2.2e-33 115.1 0.0 2.4e-15 56.4 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89377.1 - 1.8e-17 62.9 0.2 4.1e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89377.1 - 2.1e-06 27.6 0.0 2.1e-06 27.6 0.0 3.6 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit PIGA PF08288.7 GAO89378.1 - 4.4e-47 158.3 4.2 5.1e-47 158.1 1.1 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 GAO89378.1 - 1.2e-28 99.6 0.0 2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO89378.1 - 2.1e-16 60.2 0.0 3.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAO89378.1 - 3.5e-08 33.7 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 GAO89378.1 - 0.00013 21.7 0.2 0.00028 20.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 GAO89378.1 - 0.0023 18.1 0.0 0.0069 16.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.16 GAO89380.1 - 4.8e-40 136.6 0.0 2e-25 89.0 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 GAO89380.1 - 1.8e-12 46.6 0.0 2e-06 26.7 0.0 2.2 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAO89380.1 - 1.6e-07 30.7 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO89380.1 - 2.7e-07 31.1 0.0 2.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 GAO89380.1 - 4.9e-07 29.2 0.0 0.0014 18.0 0.0 2.6 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 GAO89380.1 - 1.2e-06 28.4 0.0 9e-06 25.6 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAO89380.1 - 1.4e-05 24.6 0.0 0.00033 20.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAO89380.1 - 1.4e-05 24.4 0.0 0.00014 21.1 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Pyr_redox_3 PF13738.1 GAO89381.1 - 0.016 15.2 0.0 0.16 12.0 0.0 2.5 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Prp18 PF02840.10 GAO89382.1 - 3.9e-52 175.9 0.1 3.9e-52 175.9 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 GAO89382.1 - 3.7e-12 45.2 1.1 3.7e-12 45.2 0.8 3.4 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 GAO89382.1 - 0.0098 15.2 35.2 0.016 14.5 24.4 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3584 PF12128.3 GAO89382.1 - 0.021 12.1 16.4 0.033 11.5 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MIP-T3 PF10243.4 GAO89382.1 - 0.22 9.9 27.0 0.3 9.4 18.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 GAO89382.1 - 0.5 9.5 23.3 0.69 9.0 16.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAP18 PF06487.7 GAO89383.1 - 2e-48 163.2 0.0 2.4e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.7 GAO89384.1 - 0.00044 20.0 0.1 0.00048 19.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MitoNEET_N PF10660.4 GAO89384.1 - 0.049 13.4 0.1 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus GST_N_3 PF13417.1 GAO89385.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO89385.1 - 6.7e-08 32.5 0.0 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO89385.1 - 4.7e-07 29.6 0.0 8.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO89385.1 - 4.7e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO89385.1 - 7.6e-06 26.3 0.0 1.6e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO89385.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAO89386.1 - 1.1e-41 142.2 0.0 1.1e-27 96.6 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 GAO89386.1 - 1.3e-30 105.4 0.1 2.7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 GAO89386.1 - 4.6e-23 81.3 0.0 2.4e-18 66.2 0.0 2.8 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 GAO89386.1 - 8e-05 22.4 0.2 0.00044 20.0 0.1 2.4 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 GAO89386.1 - 0.013 15.3 0.0 1.5 8.6 0.0 2.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 GAO89386.1 - 0.044 13.2 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cellsynth_D PF03500.8 GAO89386.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cellulose synthase subunit D ThiF PF00899.16 GAO89386.1 - 0.074 12.8 0.2 0.48 10.2 0.1 2.4 1 1 0 1 1 1 0 ThiF family Glycos_transf_1 PF00534.15 GAO89387.1 - 5.1e-35 120.4 0.0 8.4e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO89387.1 - 3.2e-16 59.6 0.1 1.2e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAO89387.1 - 4.8e-12 46.2 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 GAO89387.1 - 6.9e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAO89387.1 - 1.5e-08 34.5 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 GAO89387.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF2275 PF10039.4 GAO89387.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) 2-Hacid_dh_C PF02826.14 GAO89388.1 - 5.2e-56 188.6 0.0 7.5e-56 188.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO89388.1 - 8.7e-28 96.4 0.0 1.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAO89388.1 - 0.00038 20.3 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 GAO89388.1 - 0.018 14.6 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 GAO89388.1 - 0.028 13.8 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 GAO89388.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FYVE PF01363.16 GAO89391.1 - 6.1e-16 58.0 6.6 9.5e-16 57.4 4.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 GAO89391.1 - 0.024 14.4 1.0 0.059 13.2 0.7 1.6 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 GAO89391.1 - 0.029 14.2 9.4 0.058 13.2 6.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Acetyltransf_1 PF00583.19 GAO89392.1 - 1.3e-10 41.1 0.4 2e-09 37.3 0.3 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 GAO89392.1 - 8.2e-08 32.7 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO89392.1 - 3.4e-06 27.1 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO89392.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 GAO89392.1 - 0.0012 18.9 0.2 0.007 16.4 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO89392.1 - 0.014 15.1 0.3 0.65 9.7 0.1 2.4 1 1 0 2 2 2 0 FR47-like protein DUF3122 PF11320.3 GAO89392.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Acetyltransf_9 PF13527.1 GAO89392.1 - 0.086 12.6 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 GAO89392.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Nol1_Nop2_Fmu PF01189.12 GAO89393.1 - 1.1e-14 54.4 0.0 5e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Cut8_N PF14482.1 GAO89393.1 - 0.00057 19.8 1.1 0.0015 18.4 0.8 1.7 1 0 0 1 1 1 1 Cut8 proteasome-binding domain BTB_2 PF02214.17 GAO89394.1 - 1.5e-08 34.6 0.6 3.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 GAO89394.1 - 0.0021 18.0 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain GMC_oxred_N PF00732.14 GAO89395.1 - 4.8e-44 150.7 0.1 7.2e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO89395.1 - 1.3e-31 109.8 1.4 2e-30 105.9 0.2 2.5 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 GAO89395.1 - 2.7e-08 33.1 0.2 3.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO89395.1 - 1.8e-07 30.3 2.4 7.1e-07 28.4 1.7 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAO89395.1 - 1.8e-06 27.9 0.1 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO89395.1 - 1.1e-05 25.2 0.1 4.6e-05 23.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAO89395.1 - 1.3e-05 24.4 0.1 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAO89395.1 - 0.00011 21.3 0.1 0.00024 20.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAO89395.1 - 0.0013 17.9 0.2 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO89395.1 - 0.0043 15.9 0.0 0.021 13.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAO89395.1 - 0.0061 15.0 0.0 0.013 13.9 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 GAO89395.1 - 0.036 14.4 0.2 0.29 11.5 0.0 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAO89395.1 - 0.096 12.5 0.3 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 GAO89395.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GST_N PF02798.15 GAO89396.1 - 2.3e-12 46.8 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO89396.1 - 2.9e-11 43.1 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAO89396.1 - 2.7e-10 40.3 0.0 4.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO89396.1 - 1.2e-08 34.6 0.1 2.8e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO89396.1 - 4.5e-07 30.2 0.0 7.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO89396.1 - 3.2e-06 27.0 0.0 6.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 GAO89397.1 - 0.00067 19.3 0.9 0.0012 18.5 0.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO89397.1 - 0.0011 18.6 0.1 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain DZR PF12773.2 GAO89397.1 - 1.8 8.4 7.0 18 5.2 3.5 2.9 2 1 0 2 2 2 0 Double zinc ribbon Aldo_ket_red PF00248.16 GAO89398.1 - 1.2e-69 234.2 0.0 1.4e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 GAO89399.1 - 1.9e-17 63.0 0.4 3.8e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89399.1 - 5.1e-08 32.6 8.5 5.1e-08 32.6 5.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAO89400.1 - 3.9e-23 81.7 17.3 6.9e-23 80.9 12.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily YoqO PF14037.1 GAO89400.1 - 0.051 13.6 0.5 0.2 11.7 0.3 2.0 1 0 0 1 1 1 0 YoqO-like protein DUF4500 PF14937.1 GAO89400.1 - 0.059 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TauD PF02668.11 GAO89401.1 - 1.8e-48 165.4 0.0 2.2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pyr_redox PF00070.22 GAO89402.1 - 6.3e-11 42.5 1.2 5.7e-10 39.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO89402.1 - 5.2e-07 29.7 0.0 0.063 13.1 0.1 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO89402.1 - 9.9e-05 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAO89402.1 - 0.00011 21.2 0.8 0.056 12.3 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO89402.1 - 0.00074 19.6 0.0 1.5 8.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAO89402.1 - 0.0045 15.9 0.1 0.015 14.2 0.0 1.8 1 1 1 2 2 2 1 Lycopene cyclase protein AMP-binding PF00501.23 GAO89403.1 - 1.8e-96 323.1 0.0 2.2e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO89403.1 - 5.9e-13 49.5 0.1 1.3e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 GAO89404.1 - 2.6e-225 747.5 0.0 1.3e-74 251.0 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAO89404.1 - 6e-163 540.8 0.0 1.4e-36 125.9 0.0 5.4 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 GAO89404.1 - 1.8e-48 162.6 7.6 1.2e-08 35.0 0.3 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO89404.1 - 3.2e-21 76.0 2.0 1.1e-10 42.2 0.0 4.3 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAO89404.1 - 2.5e-05 22.9 0.0 0.6 8.4 0.0 4.1 5 0 0 5 5 5 2 Transferase family AATase PF07247.7 GAO89404.1 - 0.0015 17.1 0.1 4.9 5.5 0.0 3.7 4 0 0 4 4 4 2 Alcohol acetyltransferase Glyco_hydro_28 PF00295.12 GAO89405.1 - 9.4e-95 317.2 21.5 1.1e-94 317.0 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AcetylCoA_hyd_C PF13336.1 GAO89405.1 - 5.1 6.7 7.4 0.48 10.0 0.4 2.5 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain fn3_3 PF14686.1 GAO89406.1 - 1.9e-14 53.5 0.6 1.9e-14 53.5 0.4 2.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 GAO89406.1 - 2.2e-13 50.2 0.1 5.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 GAO89406.1 - 9.3e-06 25.6 2.1 1.6e-05 24.8 0.6 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 GAO89407.1 - 1.9e-28 99.0 0.0 2.7e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hydrophobin PF01185.13 GAO89408.1 - 2.7e-15 56.5 8.6 3.5e-15 56.1 5.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin SKG6 PF08693.5 GAO89409.1 - 0.018 14.3 2.0 0.042 13.1 1.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.2 GAO89409.1 - 0.057 12.6 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2650 PF10853.3 GAO89409.1 - 0.64 9.5 4.3 1.8 8.0 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Ferric_reduct PF01794.14 GAO89410.1 - 9.2e-21 74.2 15.1 9.2e-21 74.2 10.4 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO89410.1 - 1.3e-15 57.6 0.0 1.8e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO89410.1 - 5.6e-09 35.8 0.0 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 GAO89410.1 - 4.1e-07 30.5 0.0 8.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain bZIP_1 PF00170.16 GAO89416.1 - 2.1e-09 37.1 12.2 2.1e-09 37.1 8.5 2.5 2 1 1 3 3 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAO89416.1 - 1.2e-06 28.1 18.1 5.8e-05 22.8 8.1 2.3 1 1 1 2 2 2 2 Basic region leucine zipper OmpH PF03938.9 GAO89416.1 - 0.0039 17.1 1.7 0.0053 16.7 1.2 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Transposase_22 PF02994.9 GAO89416.1 - 0.004 15.7 2.5 0.0052 15.3 1.7 1.1 1 0 0 1 1 1 1 L1 transposable element Laminin_I PF06008.9 GAO89416.1 - 0.0074 15.6 7.2 0.013 14.8 4.9 1.5 1 1 0 1 1 1 1 Laminin Domain I HALZ PF02183.13 GAO89416.1 - 0.0094 15.6 2.5 0.013 15.1 1.0 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 GAO89416.1 - 0.011 16.0 1.6 0.011 16.0 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 GAO89416.1 - 0.019 14.5 5.2 0.024 14.2 3.6 1.3 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 GAO89416.1 - 0.043 13.7 8.0 0.061 13.2 5.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.6 GAO89416.1 - 0.053 13.4 3.8 0.11 12.4 2.6 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase PilJ PF13675.1 GAO89416.1 - 0.062 13.6 1.5 0.17 12.2 0.3 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_Maf PF03131.12 GAO89416.1 - 0.07 13.4 21.0 0.041 14.1 11.2 2.6 2 1 1 3 3 3 0 bZIP Maf transcription factor Flu_NS1 PF00600.14 GAO89416.1 - 0.096 11.8 1.6 0.15 11.1 1.1 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) DUF1444 PF07285.6 GAO89416.1 - 0.5 9.6 3.7 1.9 7.7 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1444) Spt5_N PF11942.3 GAO89416.1 - 1 10.0 6.2 1.9 9.1 4.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF904 PF06005.7 GAO89416.1 - 1.1 9.6 8.2 0.065 13.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 GAO89416.1 - 1.2 8.1 8.6 1.6 7.6 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3220 PF11516.3 GAO89416.1 - 1.3 9.0 4.9 0.69 9.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3120) Jnk-SapK_ap_N PF09744.4 GAO89416.1 - 2.1 8.3 11.0 2.9 7.8 7.6 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.1 GAO89416.1 - 2.2 7.1 5.7 3.1 6.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans_2 PF11951.3 GAO89417.1 - 3.1e-11 42.5 6.9 7.6e-10 37.9 4.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.3 GAO89419.1 - 0.0012 18.3 0.1 0.0012 18.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Sugar_tr PF00083.19 GAO89421.1 - 4.7e-79 266.0 23.4 5.3e-79 265.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89421.1 - 9e-34 116.7 27.8 1.4e-28 99.6 5.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO89421.1 - 4.4e-07 28.6 24.9 2.4e-05 22.9 1.0 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 GAO89421.1 - 0.0022 16.2 0.7 0.0022 16.2 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAO89421.1 - 0.0078 14.3 5.9 0.02 13.0 0.3 2.7 3 0 0 3 3 3 2 Transmembrane secretion effector UNC-93 PF05978.11 GAO89421.1 - 0.022 14.2 11.1 0.089 12.2 0.6 3.1 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Glyco_hydro_43 PF04616.9 GAO89422.1 - 3.4e-33 114.9 5.3 4.5e-33 114.5 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RPE65 PF03055.10 GAO89423.1 - 1.7e-119 399.5 1.9 2e-119 399.3 1.3 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CP2 PF04516.10 GAO89425.1 - 7.8e-83 277.1 0.0 1.3e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor bZIP_1 PF00170.16 GAO89426.1 - 6.7e-06 25.9 18.8 1.3e-05 25.0 13.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAO89426.1 - 0.092 12.5 18.3 0.16 11.8 12.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Mnd1 PF03962.10 GAO89426.1 - 0.37 10.4 6.9 0.56 9.8 4.8 1.3 1 0 0 1 1 1 0 Mnd1 family CAF-1_p150 PF11600.3 GAO89426.1 - 0.65 9.3 22.0 0.96 8.7 15.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Paramyxo_C PF01692.13 GAO89426.1 - 1.4 8.5 11.8 1.7 8.2 7.6 1.5 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c SOBP PF15279.1 GAO89426.1 - 8.2 6.7 13.5 11 6.2 9.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HSP9_HSP12 PF04119.7 GAO89427.1 - 1.2e-27 95.7 8.8 1.2e-27 95.7 6.1 2.4 3 0 0 3 3 3 1 Heat shock protein 9/12 adh_short PF00106.20 GAO89428.1 - 1.6e-23 83.4 0.2 2.6e-22 79.5 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89428.1 - 6.2e-20 71.9 0.5 1.5e-19 70.7 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89428.1 - 6e-10 39.0 0.1 1.3e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAO89428.1 - 0.00059 19.9 0.3 0.0015 18.6 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAO89428.1 - 0.0019 18.2 1.2 0.037 14.0 0.8 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO89428.1 - 0.0051 16.2 0.2 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAO89428.1 - 0.007 15.5 0.2 0.025 13.7 0.1 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) STAT_int PF02865.12 GAO89428.1 - 0.096 12.6 0.3 0.35 10.8 0.1 1.8 1 1 1 2 2 2 0 STAT protein, protein interaction domain CFEM PF05730.6 GAO89429.1 - 7e-05 22.5 11.5 0.00065 19.4 8.0 2.2 1 1 0 1 1 1 1 CFEM domain Peptidase_S41 PF03572.13 GAO89430.1 - 3.6e-07 29.7 0.0 7.3e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_3 PF00933.16 GAO89431.1 - 2.8e-89 299.0 0.1 4.1e-89 298.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO89431.1 - 4.5e-42 144.1 0.3 5.8e-41 140.4 0.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO89431.1 - 5.2e-19 67.9 0.0 1.3e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4066 PF13278.1 GAO89431.1 - 8.8e-15 54.3 0.0 2.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAO89431.1 - 4.7e-06 26.1 0.0 4.8e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 DJ-1/PfpI family Protoglobin PF11563.3 GAO89432.1 - 0.00025 20.7 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Protoglobin Globin PF00042.17 GAO89432.1 - 0.0043 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 GAO89432.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HPP PF04982.8 GAO89433.1 - 7.6e-35 119.3 7.6 7.6e-35 119.3 5.3 1.5 2 0 0 2 2 2 1 HPP family Fungal_trans_2 PF11951.3 GAO89435.1 - 1.3e-37 129.2 4.3 2.6e-37 128.3 3.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAO89436.1 - 4.8e-34 117.6 26.0 7.1e-34 117.0 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89436.1 - 1e-05 24.3 26.3 0.00089 17.9 7.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO89437.1 - 2.9e-17 62.4 37.4 2.9e-17 62.4 25.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAO89437.1 - 6.7e-09 35.4 4.0 6.7e-09 35.4 2.8 3.3 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 PsbX PF06596.6 GAO89437.1 - 0.44 10.2 5.7 0.59 9.8 0.4 3.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Lig_chan PF00060.21 GAO89437.1 - 2.9 7.5 5.5 3.6 7.2 0.1 3.2 3 0 0 3 3 3 0 Ligand-gated ion channel ABC2_membrane_4 PF12730.2 GAO89437.1 - 6.8 5.7 32.1 0.77 8.8 4.6 3.5 2 2 0 2 2 2 0 ABC-2 family transporter protein BcrAD_BadFG PF01869.15 GAO89438.1 - 1.7e-19 70.1 0.3 1.4e-18 67.1 0.1 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 GAO89438.1 - 0.00044 19.8 0.2 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 GAO89438.1 - 0.037 13.7 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 SIS domain SSF PF00474.12 GAO89439.1 - 3.1e-20 72.1 27.1 3.1e-20 72.1 18.8 2.2 2 1 1 3 3 3 1 Sodium:solute symporter family Bac_luciferase PF00296.15 GAO89440.1 - 6e-64 216.0 4.0 7.5e-64 215.7 2.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Phosphoesterase PF04185.9 GAO89441.1 - 1.5e-65 221.8 0.3 2e-65 221.4 0.2 1.2 1 0 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.19 GAO89442.1 - 3.7e-64 216.9 20.0 5.4e-61 206.5 9.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAO89442.1 - 6.3e-10 38.2 48.7 9.7e-05 21.2 20.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 GAO89445.1 - 4.8e-16 58.4 48.9 8.7e-10 37.8 16.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89445.1 - 0.0012 17.4 13.3 0.0012 17.4 9.2 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 GAO89446.1 - 1.1e-18 67.0 1.2 1.9e-18 66.2 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_12 PF13424.1 GAO89448.1 - 6.9e-46 154.0 18.7 4e-15 55.4 0.3 5.0 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAO89448.1 - 4e-41 137.7 28.7 5e-09 35.7 0.7 7.4 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89448.1 - 2.7e-14 51.8 14.5 0.041 13.8 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAO89448.1 - 7.1e-14 51.2 9.2 0.00022 20.8 0.1 4.5 3 1 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAO89448.1 - 6.4e-13 47.7 10.3 0.12 11.9 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat MFS_1 PF07690.11 GAO89448.1 - 1.3e-11 43.8 57.0 4.3e-08 32.2 12.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 GAO89448.1 - 7.9e-11 41.5 0.8 1.7e-10 40.5 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain TPR_7 PF13176.1 GAO89448.1 - 4.6e-10 38.5 16.3 0.012 15.3 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat BBE PF08031.7 GAO89448.1 - 3.5e-09 36.4 0.0 8.1e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAO89448.1 - 3.7e-08 32.3 0.1 2.3e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Cytochrome P450 TPR_16 PF13432.1 GAO89448.1 - 1.5e-06 28.6 19.7 0.0096 16.5 0.2 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO89448.1 - 2.2e-06 27.0 0.3 2.3 8.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAO89448.1 - 3.1e-05 23.8 1.3 5.8 7.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAO89448.1 - 0.0013 18.9 10.2 8.4 7.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAO89448.1 - 0.0014 18.9 7.2 0.054 13.8 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat RepA_C PF04796.7 GAO89448.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded RepA protein TPR_14 PF13428.1 GAO89448.1 - 0.16 12.7 18.4 5 8.0 0.0 6.5 6 1 1 7 7 6 0 Tetratricopeptide repeat Amastin PF07344.6 GAO89448.1 - 1.3 8.5 10.3 4.8 6.7 0.4 2.8 3 0 0 3 3 3 0 Amastin surface glycoprotein DUF829 PF05705.9 GAO89449.1 - 2.9e-22 79.5 0.0 3.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) CN_hydrolase PF00795.17 GAO89450.1 - 2.5e-25 88.8 0.0 3.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3836 PF12930.2 GAO89452.1 - 0.064 12.7 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Transferase PF02458.10 GAO89453.1 - 9.3e-21 73.7 0.0 1.1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Transferase family DUF4485 PF14846.1 GAO89453.1 - 0.0055 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) Trp_DMAT PF11991.3 GAO89454.1 - 3.6e-85 286.3 0.1 2.9e-84 283.3 0.1 1.9 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Condensation PF00668.15 GAO89455.1 - 2.7e-05 23.1 0.0 4.4e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.23 GAO89456.1 - 8.7e-250 828.1 0.5 4.4e-87 292.1 0.0 3.5 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 GAO89456.1 - 1.2e-129 431.4 0.0 8.6e-34 116.7 0.0 5.7 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.20 GAO89456.1 - 1.5e-34 118.0 0.1 9.5e-12 45.0 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO89456.1 - 7.1e-17 62.1 0.1 2e-06 28.6 0.0 4.0 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain PhyH PF05721.8 GAO89457.1 - 6.1e-28 98.3 0.0 7.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAO89457.1 - 0.011 14.2 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Beta-lactamase PF00144.19 GAO89458.1 - 3.7e-23 82.0 0.0 1.6e-21 76.6 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase 3HCDH_N PF02737.13 GAO89458.1 - 0.26 10.9 0.3 0.57 9.8 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.8 GAO89459.1 - 7.4e-29 101.2 0.0 2.2e-25 89.9 0.0 2.1 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 GAO89460.1 - 1.6e-54 185.2 0.0 2.2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.22 GAO89460.1 - 0.00013 21.6 0.8 0.00087 18.9 0.6 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO89460.1 - 0.00023 20.7 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO89460.1 - 0.0047 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BON PF04972.12 GAO89461.1 - 0.077 12.7 2.2 0.18 11.6 0.2 2.3 3 0 0 3 3 3 0 BON domain ketoacyl-synt PF00109.21 GAO89462.1 - 3.3e-75 252.8 0.2 7.1e-75 251.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAO89462.1 - 1.4e-37 128.1 0.0 3.3e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAO89462.1 - 6.3e-26 91.4 0.0 2.7e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAO89462.1 - 1.3e-20 73.7 0.0 2.9e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 GAO89462.1 - 2.7e-19 69.4 0.0 7.2e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 GAO89462.1 - 6.8e-14 51.9 0.1 5.1e-11 42.5 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 GAO89462.1 - 1.4e-11 44.4 0.0 5.2e-10 39.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAO89462.1 - 3.1e-11 43.3 0.0 7.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 GAO89462.1 - 7.3e-11 42.0 0.0 2.2e-08 34.0 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO89462.1 - 2.8e-10 39.7 0.0 1.3e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 GAO89462.1 - 1.3e-09 37.8 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO89462.1 - 2.2e-07 31.2 0.0 5.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO89462.1 - 1e-06 29.2 0.0 3.6e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO89462.1 - 2.2e-06 26.8 0.1 4.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 GAO89462.1 - 1.4e-05 25.3 0.0 4.7e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAO89462.1 - 0.00017 21.1 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAO89462.1 - 0.00035 20.5 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 GAO89462.1 - 0.00074 19.1 0.0 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Abhydrolase_2 PF02230.11 GAO89462.1 - 0.0083 15.5 0.0 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_PK PF05891.7 GAO89462.1 - 0.0087 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DLH PF01738.13 GAO89462.1 - 0.021 14.0 0.0 1.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Dienelactone hydrolase family COesterase PF00135.23 GAO89462.1 - 0.63 8.6 0.0 1.1 7.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family FAD_binding_3 PF01494.14 GAO89463.1 - 7.5e-27 94.2 0.0 1.8e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAO89463.1 - 4.7e-09 35.6 0.3 0.0012 17.8 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAO89463.1 - 3e-06 26.3 0.1 0.0017 17.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 GAO89463.1 - 4.2e-06 26.1 0.2 0.015 14.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAO89463.1 - 1e-05 25.4 0.1 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO89463.1 - 3.9e-05 23.9 0.3 0.00031 21.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO89463.1 - 0.009 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO89463.1 - 0.011 14.6 0.1 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain B12-binding PF02310.14 GAO89463.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain UbiA PF01040.13 GAO89464.1 - 5.9e-32 110.8 12.9 7.5e-32 110.5 8.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4401 PF14351.1 GAO89464.1 - 0.24 10.3 9.1 0.093 11.7 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4401) p450 PF00067.17 GAO89466.1 - 2.6e-20 72.4 0.0 3.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spt20 PF12090.3 GAO89467.1 - 0.0014 18.0 0.2 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 Spt20 family D-ser_dehydrat PF14031.1 GAO89467.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine dehydratase domain CDC50 PF03381.10 GAO89468.1 - 1.3e-89 300.0 0.0 2e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SWIRM PF04433.12 GAO89468.1 - 3.6e-15 55.8 0.0 1e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Peptidase_M43 PF05572.8 GAO89468.1 - 1.3e-14 54.0 0.0 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 GAO89468.1 - 0.0017 18.2 0.1 0.0035 17.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAO89468.1 - 0.025 14.6 0.1 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAO89468.1 - 0.093 12.2 0.6 0.21 11.0 0.3 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like SPT16 PF08644.6 GAO89469.1 - 3.1e-60 202.4 0.0 7.4e-60 201.2 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 GAO89469.1 - 6.6e-53 178.5 0.0 2.5e-52 176.7 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 GAO89469.1 - 4.6e-21 74.6 0.2 2e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 GAO89469.1 - 2.4e-14 53.4 0.0 2.7e-13 49.9 0.0 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 Sugar_tr PF00083.19 GAO89470.1 - 4.6e-99 332.0 11.3 6.2e-99 331.5 7.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89470.1 - 1.6e-31 109.3 43.9 2.5e-29 102.1 12.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 GAO89470.1 - 3.6e-17 61.8 6.5 4.4e-14 51.9 0.0 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein MFS_1_like PF12832.2 GAO89470.1 - 0.0077 16.0 0.4 0.026 14.3 0.1 2.0 2 0 0 2 2 2 1 MFS_1 like family 5HT_transporter PF03491.8 GAO89470.1 - 0.019 15.0 1.1 0.21 11.7 0.2 2.4 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus PMT PF02366.13 GAO89471.1 - 7.1e-86 287.5 18.0 7.1e-86 287.5 12.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAO89471.1 - 5e-40 137.0 0.0 7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 GAO89472.1 - 2e-43 147.6 0.7 8.1e-38 129.3 0.0 2.4 2 1 0 2 2 2 2 Ras family Miro PF08477.8 GAO89472.1 - 5.1e-13 49.5 0.1 4.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 GAO89472.1 - 1.3e-10 40.7 0.1 2e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO89472.1 - 3.9e-08 32.9 0.0 6.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAO89472.1 - 1.3e-05 24.4 0.2 5.6e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_30 PF13604.1 GAO89472.1 - 0.024 14.2 0.2 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TAT_signal PF10518.4 GAO89472.1 - 0.057 13.4 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Choline_transpo PF04515.7 GAO89473.1 - 1.4e-09 37.2 29.7 2.3e-09 36.4 11.5 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 GAO89475.1 - 3.9e-49 166.9 0.0 4.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3212 PF11486.3 GAO89475.1 - 0.1 12.3 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) UPF0061 PF02696.9 GAO89476.1 - 5.7e-118 394.2 0.0 6.9e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.18 GAO89477.1 - 6.6e-39 130.0 52.6 1.7e-08 33.9 0.9 7.1 6 1 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 GAO89477.1 - 2.5e-09 36.6 37.1 0.024 14.2 0.4 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 GAO89477.1 - 3e-06 26.7 30.8 0.014 15.0 1.3 5.2 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 GAO89477.1 - 0.00013 21.6 37.1 0.042 13.5 0.2 5.9 3 2 3 6 6 6 5 Zinc knuckle SAE2 PF08573.5 GAO89478.1 - 3.3e-34 117.4 1.3 3.3e-34 117.4 0.9 2.2 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Pex16 PF08610.5 GAO89479.1 - 2.5e-81 273.2 0.3 2.8e-81 273.1 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 GAO89480.1 - 2.3e-46 157.9 0.0 8.9e-46 156.0 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease HII Mif2_N PF15624.1 GAO89481.1 - 1.1e-34 119.9 1.0 1.1e-34 119.9 0.7 3.8 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 GAO89481.1 - 6.9e-33 112.4 0.5 1.2e-32 111.7 0.3 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 GAO89481.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Colicin_im PF03857.8 GAO89481.1 - 0.37 10.5 0.0 0.66 9.7 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein GAGA_bind PF06217.7 GAO89481.1 - 6.1 6.7 13.0 22 4.9 6.1 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family CAP_GLY PF01302.20 GAO89482.1 - 7.4e-29 99.2 0.1 1.2e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 GAO89482.1 - 5.1e-15 55.5 0.0 9.9e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 GAO89482.1 - 2.4e-06 26.8 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 GAO89483.1 - 3.9e-14 52.9 0.0 6.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO89483.1 - 3.1e-09 36.7 0.0 1.8e-08 34.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO89483.1 - 1.3e-07 31.8 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO89483.1 - 4e-06 26.4 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO89483.1 - 7.8e-06 26.2 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO89483.1 - 0.00055 20.4 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO89483.1 - 0.028 13.7 0.0 0.05 12.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DnaB_bind PF10410.4 GAO89483.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Methyltransf_9 PF08003.6 GAO89483.1 - 0.097 11.3 0.1 0.36 9.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Myb_DNA-binding PF00249.26 GAO89484.1 - 1.2e-11 44.4 2.8 1.8e-09 37.5 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO89484.1 - 1.6e-07 31.3 5.0 4.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.24 GAO89485.1 - 6.2e-25 87.8 0.1 8.4e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO89485.1 - 7.5e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.1 GAO89486.1 - 7.8e-40 135.5 0.3 2e-39 134.2 0.2 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAO89486.1 - 7.3e-29 99.8 0.1 1.9e-28 98.4 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 GAO89487.1 - 6.7e-62 207.8 0.1 9.4e-62 207.3 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAO89487.1 - 3.1e-15 55.5 0.0 8e-15 54.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAO89487.1 - 2.7e-06 27.3 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO89487.1 - 3.5e-06 27.8 0.0 6e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO89487.1 - 0.00037 20.8 0.0 0.00088 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAO89487.1 - 0.0006 18.9 0.0 0.00099 18.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Myosin_tail_1 PF01576.14 GAO89487.1 - 0.0029 15.4 1.0 0.0033 15.2 0.1 1.5 2 0 0 2 2 2 1 Myosin tail AAA_28 PF13521.1 GAO89487.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAO89487.1 - 0.097 11.8 0.1 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 GAO89487.1 - 0.11 11.8 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase GFO_IDH_MocA PF01408.17 GAO89488.1 - 3.3e-19 69.5 0.1 5.3e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAO89488.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CTD_bind PF04818.8 GAO89489.1 - 0.0053 16.9 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 GAO89489.1 - 0.0069 15.8 3.0 0.079 12.4 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 CFIA_Pcf11 PF11526.3 GAO89489.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 GAO89489.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 VHS domain zf-C2HC_2 PF13913.1 GAO89489.1 - 0.48 10.1 5.7 3 7.6 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 GAO89489.1 - 1.1 9.2 4.0 18 5.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HOOK PF05622.7 GAO89490.1 - 6.1e-24 83.8 42.3 6.1e-24 83.8 29.3 2.8 1 1 1 2 2 2 1 HOOK protein Fib_alpha PF08702.5 GAO89490.1 - 0.0079 16.3 6.3 0.0079 16.3 4.4 5.7 4 2 2 6 6 6 2 Fibrinogen alpha/beta chain family ATG16 PF08614.6 GAO89490.1 - 6.5 6.5 72.5 0.56 10.0 12.9 5.0 4 1 2 6 6 6 0 Autophagy protein 16 (ATG16) Coprogen_oxidas PF01218.13 GAO89491.1 - 9.6e-121 401.8 0.0 2.9e-120 400.2 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 GAO89492.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 GAO89492.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.22 GAO89493.1 - 2.3e-28 97.7 2.1 1.9e-15 56.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 GAO89494.1 - 1.3e-06 27.8 0.1 2.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) HSP70 PF00012.15 GAO89495.1 - 1e-273 908.7 8.0 1.2e-273 908.5 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO89495.1 - 6.5e-18 64.4 0.1 7.4e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAO89495.1 - 0.00012 21.7 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 GAO89495.1 - 0.0022 17.7 1.7 0.5 10.2 0.1 3.2 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 GAO89495.1 - 0.0032 16.6 0.1 0.036 13.1 0.0 2.4 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase Macoilin PF09726.4 GAO89495.1 - 0.033 12.4 1.9 0.064 11.5 0.4 1.8 2 0 0 2 2 2 0 Transmembrane protein CHZ PF09649.5 GAO89496.1 - 1.8e-20 71.8 1.0 1.8e-20 71.8 0.7 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ SNARE PF05739.14 GAO89497.1 - 3.5e-06 26.6 1.3 5.2e-06 26.0 0.9 1.3 1 0 0 1 1 1 1 SNARE domain ATP_bind_2 PF03668.10 GAO89497.1 - 0.05 12.6 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family DUF639 PF04842.7 GAO89497.1 - 0.053 11.6 0.0 0.063 11.4 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Apc15p PF05841.6 GAO89498.1 - 3.9e-26 92.2 0.7 3.9e-26 92.2 0.5 2.3 2 0 0 2 2 2 1 Apc15p protein DUF4588 PF15251.1 GAO89498.1 - 0.024 14.6 0.9 0.024 14.6 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) Glu_synthase PF01645.12 GAO89499.1 - 4.1e-160 532.6 0.0 5.9e-160 532.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 GAO89499.1 - 5.1e-142 472.8 0.0 1.1e-141 471.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 GAO89499.1 - 2.2e-120 401.2 0.0 6.6e-120 399.7 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 GAO89499.1 - 2.8e-65 219.1 3.3 5.3e-65 218.2 2.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 GAO89499.1 - 1.9e-22 78.9 0.1 4.5e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 GAO89499.1 - 1.7e-18 67.2 0.0 4.9e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO89499.1 - 1.5e-10 41.5 0.7 0.0002 21.5 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAO89499.1 - 5.4e-09 35.9 0.6 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO89499.1 - 7e-09 35.9 0.1 9e-06 26.0 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO89499.1 - 6.2e-07 28.8 0.2 9.6e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAO89499.1 - 2.7e-06 26.5 1.8 9e-05 21.5 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAO89499.1 - 3.4e-05 22.5 0.2 3.4e-05 22.5 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAO89499.1 - 3.6e-05 23.0 0.4 7.3e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAO89499.1 - 6.8e-05 23.0 0.1 0.36 11.1 0.1 3.0 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.19 GAO89499.1 - 7.6e-05 21.7 0.7 0.00016 20.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 GAO89499.1 - 0.00026 20.5 0.1 0.014 14.9 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 GAO89499.1 - 0.00067 18.8 0.1 0.0023 17.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAO89499.1 - 0.003 16.7 0.1 0.012 14.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 GAO89499.1 - 0.01 14.7 0.1 0.01 14.7 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 GAO89499.1 - 0.014 15.1 0.1 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 GAO89499.1 - 0.022 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family FMO-like PF00743.14 GAO89499.1 - 0.023 12.8 0.1 0.56 8.3 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.13 GAO89499.1 - 0.064 12.0 1.3 0.2 10.4 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.15 GAO89499.1 - 0.12 12.5 0.2 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAO89499.1 - 0.17 11.0 0.3 0.51 9.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAO89499.1 - 2.1 7.9 4.5 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 GAO89501.1 - 5.7e-30 103.2 1.9 9.9e-30 102.5 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 GAO89502.1 - 2e-171 570.2 0.3 2.8e-171 569.7 0.0 1.3 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 GAO89502.1 - 1.2e-09 37.6 0.0 2.4e-07 30.2 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO89502.1 - 4e-07 29.7 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 GAO89502.1 - 7e-05 22.6 0.0 0.00021 21.0 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase RRM_6 PF14259.1 GAO89502.1 - 0.00041 20.2 0.0 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 GAO89502.1 - 0.0074 16.0 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) AAA_16 PF13191.1 GAO89502.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF4519 PF15012.1 GAO89502.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) p450 PF00067.17 GAO89503.1 - 8.8e-24 83.8 0.0 3.2e-23 82.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ILVD_EDD PF00920.16 GAO89504.1 - 7.7e-164 545.9 0.1 9.6e-164 545.6 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 GAO89504.1 - 5.1e-21 73.7 3.5 9.1e-10 38.0 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 GAO89504.1 - 3.3e-08 33.3 0.2 1.2e-07 31.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 GAO89504.1 - 5.1e-07 29.5 0.7 2.8e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 GAO89504.1 - 4.1e-05 22.5 0.0 7.6e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region DNA_pol_alpha_N PF12254.3 GAO89504.1 - 0.064 13.0 1.4 0.16 11.7 1.0 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 GAO89504.1 - 0.065 11.0 0.2 0.25 9.1 0.1 1.9 1 1 0 1 1 1 0 IKI3 family Apc4_WD40 PF12894.2 GAO89504.1 - 0.085 12.3 0.0 0.84 9.1 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.11 GAO89506.1 - 2e-40 138.6 18.7 2e-40 138.6 13.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89506.1 - 6.2e-07 28.3 6.5 6.2e-07 28.3 4.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 GAO89506.1 - 0.0069 15.1 0.9 0.0069 15.1 0.6 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF791) TRI12 PF06609.8 GAO89506.1 - 0.0077 14.4 2.4 0.013 13.7 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 GAO89506.1 - 0.16 11.2 0.7 10 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HeLo PF14479.1 GAO89507.1 - 0.032 13.9 2.7 0.089 12.5 1.9 1.7 1 0 0 1 1 1 0 Prion-inhibition and propagation NUDIX PF00293.23 GAO89508.1 - 3.5e-15 55.8 0.0 6.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain VTC PF09359.5 GAO89509.1 - 2.5e-92 308.9 0.1 2.5e-92 308.9 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 GAO89509.1 - 5e-18 65.8 16.7 5.9e-12 45.9 3.7 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 GAO89509.1 - 5.4e-10 39.3 2.3 5.4e-10 39.3 1.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DSBA PF01323.15 GAO89510.1 - 1.5e-35 122.5 0.0 3.2e-19 69.2 0.2 2.0 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 GAO89510.1 - 0.042 13.8 0.1 0.08 12.9 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin 6PF2K PF01591.13 GAO89511.1 - 4e-70 235.3 0.0 1.7e-49 167.9 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAO89511.1 - 4e-27 95.2 0.0 9.7e-27 93.9 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAO89511.1 - 2.3e-07 30.7 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAO89511.1 - 0.0016 19.2 0.0 0.0058 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 GAO89511.1 - 0.034 13.3 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF998 PF06197.8 GAO89512.1 - 0.0027 17.0 4.0 0.37 10.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF998) DUF202 PF02656.10 GAO89512.1 - 0.033 14.4 7.8 0.28 11.4 5.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FMN_dh PF01070.13 GAO89513.1 - 6.8e-107 357.4 0.0 8.3e-107 357.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAO89513.1 - 6.4e-22 77.1 0.0 1.5e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 GAO89513.1 - 1.5e-06 27.4 0.0 0.00046 19.1 0.0 2.7 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAO89513.1 - 3.1e-06 26.3 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAO89513.1 - 0.0016 17.7 0.1 0.045 13.0 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein ATP11 PF06644.6 GAO89513.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.10 GAO89513.1 - 0.21 10.6 1.9 0.26 10.3 0.2 1.9 2 1 1 3 3 3 0 Nitronate monooxygenase APH PF01636.18 GAO89514.1 - 4e-07 30.0 0.1 5.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAO89514.1 - 2.6e-06 26.7 0.1 3.9e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 GAO89514.1 - 3.7e-05 23.3 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 GAO89514.1 - 0.022 13.7 0.0 0.042 12.8 0.0 1.6 1 0 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.6 GAO89514.1 - 0.064 11.8 0.1 0.094 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.2 GAO89515.1 - 6.2e-13 48.8 0.2 7.3e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO89515.1 - 2.7e-05 23.9 4.5 5.7 7.4 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 GAO89515.1 - 2.9e-05 23.6 2.2 0.75 9.7 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 GAO89515.1 - 4e-05 23.6 0.8 0.082 13.1 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO89515.1 - 0.00098 19.5 1.5 0.028 14.9 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3612 PF12268.3 GAO89515.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Cauli_VI PF01693.11 GAO89516.1 - 2.1e-31 107.6 10.5 8.3e-17 60.9 0.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 GAO89516.1 - 3.8e-28 98.4 0.0 6.5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 GAO89517.1 - 1.5e-40 138.9 19.5 1.9e-40 138.5 13.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UCH PF00443.24 GAO89518.1 - 8e-51 172.7 0.0 1.3e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO89518.1 - 6.4e-19 68.4 0.0 1e-17 64.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 GAO89519.1 - 2.9e-08 33.5 8.3 4.8e-08 32.9 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAO89519.1 - 3e-07 30.0 6.9 5.1e-07 29.2 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO89519.1 - 7.2e-07 28.7 5.1 1.2e-06 28.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAO89519.1 - 1e-06 28.4 7.6 1.7e-06 27.7 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAO89519.1 - 6.2e-06 25.8 4.5 1.2e-05 24.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAO89519.1 - 1.4e-05 24.8 5.8 0.00012 21.8 4.4 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAO89519.1 - 0.018 14.7 5.1 0.024 14.3 2.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 GAO89519.1 - 2.2 7.8 11.1 5.2 6.6 7.6 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger ERG4_ERG24 PF01222.12 GAO89520.1 - 3.4e-144 480.5 21.7 4e-144 480.3 15.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Chs3p PF12271.3 GAO89521.1 - 7.7e-103 343.4 8.5 1.1e-102 343.0 5.9 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DLH PF01738.13 GAO89521.1 - 4.4e-30 104.5 0.0 6.1e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO89521.1 - 3.3e-07 30.1 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAO89521.1 - 0.0027 17.4 0.0 0.49 10.0 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAO89521.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 GAO89521.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Cadherin PF00028.12 GAO89521.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain BC10 PF06726.7 GAO89522.1 - 1.9e-16 59.8 9.7 3.2e-16 59.0 6.7 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF1342 PF07072.6 GAO89523.1 - 0.036 13.7 3.5 0.087 12.4 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) dCMP_cyt_deam_1 PF00383.17 GAO89524.1 - 1.7e-05 24.3 0.3 0.00018 21.0 0.2 2.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 GAO89525.1 - 3.9e-29 101.9 0.1 8e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAO89525.1 - 3e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 GAO89526.1 - 2.8e-20 71.3 7.5 0.00031 20.4 0.0 10.4 11 0 0 11 11 11 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAO89526.1 - 5.2e-07 29.8 0.1 0.17 12.1 0.0 5.9 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 GAO89526.1 - 5.6e-05 22.8 16.2 0.75 10.0 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat Fructosamin_kin PF03881.9 GAO89527.1 - 3.6e-81 272.3 0.0 4.9e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase GST_N_3 PF13417.1 GAO89527.1 - 2.2e-24 85.4 0.1 5.6e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO89527.1 - 1.2e-17 63.6 0.0 4.2e-17 61.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain APH PF01636.18 GAO89527.1 - 4.7e-09 36.3 0.0 1.4e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family GST_N PF02798.15 GAO89527.1 - 2.1e-05 24.5 0.0 7.2e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO89527.1 - 0.00021 21.0 0.4 0.00062 19.6 0.3 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO89527.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO89527.1 - 0.023 15.1 0.1 0.086 13.3 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cyclin_N PF00134.18 GAO89528.1 - 8.9e-11 41.4 0.0 1.3e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 GAO89529.1 - 4.1e-81 272.4 26.9 5e-81 272.1 18.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 GAO89530.1 - 1.7e-65 219.1 0.2 3.3e-65 218.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) S4 PF01479.20 GAO89531.1 - 7.6e-16 57.2 0.0 1.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 GAO89531.1 - 0.037 13.6 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain SOBP PF15279.1 GAO89531.1 - 9.3 6.5 8.7 18 5.6 6.0 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Mitofilin PF09731.4 GAO89532.1 - 0.4 9.2 5.4 0.71 8.4 3.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Metal_resist PF13801.1 GAO89532.1 - 8.3 6.4 10.5 0.12 12.3 0.7 2.9 3 0 0 3 3 3 0 Heavy-metal resistance E1_dh PF00676.15 GAO89533.1 - 2.3e-114 381.1 0.5 2.8e-114 380.8 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAO89533.1 - 0.00024 20.1 0.0 0.00045 19.2 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 GAO89533.1 - 0.049 13.2 0.6 0.1 12.1 0.4 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BPL_LplA_LipB PF03099.14 GAO89534.1 - 1.9e-09 37.5 0.1 9.7e-09 35.2 0.0 2.2 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 GAO89535.1 - 1.1e-130 435.1 0.0 1.4e-130 434.8 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Kelch_4 PF13418.1 GAO89536.1 - 3.5e-08 33.0 3.6 0.047 13.4 0.1 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO89536.1 - 6.2e-06 26.1 2.3 2.2 8.5 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAO89536.1 - 3e-05 24.0 7.9 1.9 8.7 0.1 6.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO89536.1 - 5.2e-05 23.1 0.3 0.08 12.9 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 GAO89536.1 - 0.012 15.1 0.1 3.8 7.1 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.20 GAO89537.1 - 2.3e-55 187.5 0.3 9.6e-39 133.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89537.1 - 2e-27 95.9 0.1 5.9e-26 91.0 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO89537.1 - 1.7e-05 23.9 0.0 4.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO89537.1 - 0.00068 19.4 1.1 0.0042 16.8 0.7 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_53 PF07745.8 GAO89538.1 - 3.6e-111 371.1 0.2 5e-111 370.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 zf-H2C2_2 PF13465.1 GAO89538.1 - 4.8e-13 48.6 7.9 8.2e-08 32.1 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAO89538.1 - 7e-12 44.9 11.3 8.3e-06 25.8 1.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89538.1 - 1e-10 41.1 12.0 3.9e-05 23.6 1.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 GAO89538.1 - 0.00013 22.0 1.5 0.026 14.7 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO89538.1 - 0.0017 18.4 12.1 0.12 12.5 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 GAO89538.1 - 0.21 11.2 0.6 0.46 10.2 0.4 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 GAO89538.1 - 1.1 9.0 4.3 2.1 8.1 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger Glycos_transf_1 PF00534.15 GAO89539.1 - 7.9e-21 74.2 0.0 1.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAO89539.1 - 1.1e-09 38.5 0.0 2.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAO89539.1 - 0.00048 19.9 0.2 0.0016 18.1 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 GAO89539.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 60KD_IMP PF02096.15 GAO89540.1 - 1.7e-16 60.4 0.0 2.9e-16 59.7 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein DUF987 PF06174.6 GAO89541.1 - 0.027 13.9 0.1 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF987) PP2C PF00481.16 GAO89542.1 - 1.5e-43 149.0 0.0 3.2e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAO89542.1 - 5.8e-06 25.8 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAO89542.1 - 0.00015 21.5 0.1 0.52 9.9 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 GAO89543.1 - 7.6e-90 301.4 0.0 1.2e-89 300.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_16 PF13432.1 GAO89543.1 - 0.00053 20.5 0.2 0.29 11.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89543.1 - 0.0035 17.1 0.1 0.071 13.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89543.1 - 0.0053 17.2 3.3 0.27 11.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAO89543.1 - 0.024 14.2 0.9 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 GAO89543.1 - 0.049 13.5 0.3 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO89543.1 - 0.23 11.9 1.9 3.4 8.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop53 PF07767.6 GAO89543.1 - 1 8.2 13.8 1.8 7.4 9.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNase_H2-Ydr279 PF09468.5 GAO89543.1 - 1.7 7.7 6.4 3.1 6.8 4.4 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PQ-loop PF04193.9 GAO89544.1 - 3.8e-38 128.8 7.9 9.9e-21 73.0 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_60s PF00428.14 GAO89545.1 - 4.6e-26 91.0 12.6 5.4e-26 90.8 8.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein KfrA_N PF11740.3 GAO89545.1 - 0.041 14.3 6.0 0.072 13.5 4.2 1.3 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF2408 PF10303.4 GAO89546.1 - 3.4e-57 192.3 2.9 4.6e-35 120.6 0.1 4.9 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 GAO89546.1 - 0.044 14.1 4.1 0.13 12.5 0.1 3.5 5 0 0 5 5 5 0 Snapin/Pallidin DUF1992 PF09350.5 GAO89546.1 - 0.05 13.4 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) XhlA PF10779.4 GAO89546.1 - 0.2 11.5 2.1 9.6 6.2 0.1 3.4 3 0 0 3 3 3 0 Haemolysin XhlA Aconitase PF00330.15 GAO89547.1 - 4.9e-158 526.4 0.0 1.8e-157 524.5 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAO89547.1 - 8.8e-40 135.8 0.0 1.4e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Fe-ADH PF00465.14 GAO89548.1 - 3.1e-72 243.2 1.5 3.8e-72 242.9 1.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAO89548.1 - 2.8e-11 43.2 0.7 2.6e-06 26.9 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HEAT_EZ PF13513.1 GAO89549.1 - 8.7e-21 73.8 16.8 1.4e-08 34.9 0.2 10.0 8 2 1 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.1 GAO89549.1 - 3.4e-18 65.7 13.0 2.2e-07 31.0 0.4 8.5 5 2 5 10 10 10 5 HEAT repeats HEAT PF02985.17 GAO89549.1 - 6.4e-18 63.1 11.0 0.00038 20.2 0.0 11.3 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 GAO89549.1 - 1.2e-09 38.3 0.4 0.0056 17.0 0.0 6.5 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAO89549.1 - 1.8e-05 24.2 0.2 0.17 11.2 0.1 5.8 3 1 1 5 5 5 1 CLASP N terminal Arm PF00514.18 GAO89549.1 - 6.5e-05 22.5 1.6 2.3 8.1 0.1 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 GAO89549.1 - 0.00019 21.1 0.0 0.2 11.2 0.0 4.3 3 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 GAO89549.1 - 0.00057 18.3 4.2 0.0065 14.8 0.5 3.2 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 GAO89549.1 - 0.00079 19.3 1.8 3 7.6 0.1 5.0 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 GAO89549.1 - 0.00082 17.7 1.9 0.0015 16.9 0.1 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 GAO89549.1 - 0.0018 17.1 0.3 0.073 11.7 0.2 3.4 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 GAO89549.1 - 0.0024 17.7 0.1 0.057 13.3 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.3 GAO89549.1 - 0.0035 17.2 2.7 9 6.1 0.0 4.8 5 0 0 5 5 4 1 Domain of unknown function (DUF3385) DNA_alkylation PF08713.6 GAO89549.1 - 0.0084 15.6 0.0 0.048 13.1 0.0 2.3 2 0 0 2 2 2 1 DNA alkylation repair enzyme DUF4042 PF13251.1 GAO89549.1 - 0.036 13.5 0.4 12 5.3 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) CBS PF00571.23 GAO89550.1 - 1.2e-41 140.2 6.8 6e-11 41.9 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 GAO89550.1 - 2.4e-09 36.7 0.0 8.1e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.14 GAO89551.1 - 1.6e-51 173.3 6.8 1.9e-51 173.1 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 GAO89551.1 - 0.024 14.9 1.0 0.59 10.5 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 GAO89551.1 - 0.066 13.5 0.2 10 6.5 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 GAO89551.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) LRR_4 PF12799.2 GAO89552.1 - 0.0026 17.3 1.7 0.39 10.3 0.1 4.2 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAO89552.1 - 0.0045 16.9 2.1 2.3 8.5 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 GAO89552.1 - 0.081 13.0 1.6 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 GAO89552.1 - 0.081 12.6 3.4 65 3.3 0.1 4.3 4 1 1 5 5 5 0 Leucine rich repeat Gon7 PF08738.5 GAO89553.1 - 0.005 16.8 2.9 1.2 9.1 1.0 2.4 1 1 1 2 2 2 2 Gon7 family LANC_like PF05147.8 GAO89554.1 - 2.3e-26 92.2 0.0 1.4e-23 83.0 0.0 2.6 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein zf-H2C2 PF09337.5 GAO89555.1 - 2.8e-23 81.0 3.6 5.1e-23 80.2 2.5 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 GAO89555.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAO89555.1 - 0.00097 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAO89555.1 - 0.0023 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO89555.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.19 GAO89556.1 - 2e-144 481.8 2.8 2.4e-144 481.5 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.6 GAO89556.1 - 0.071 13.0 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Replication factor C C-terminal domain Peptidase_C14 PF00656.17 GAO89557.1 - 1.3e-72 244.4 0.0 1.7e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 GAO89557.1 - 0.053 13.3 0.4 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Sec31 PF11549.3 GAO89557.1 - 0.12 12.0 2.6 9.4 5.9 0.5 2.8 3 0 0 3 3 3 0 Protein transport protein SEC31 DUF367 PF04034.8 GAO89558.1 - 1.1e-47 160.7 0.1 1.6e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 GAO89558.1 - 4.1e-11 42.2 0.3 7.5e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI LcrG PF07216.7 GAO89558.1 - 0.012 15.5 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 LcrG protein CDC45 PF02724.9 GAO89558.1 - 0.036 12.1 6.4 0.048 11.6 4.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAO89558.1 - 0.32 8.8 21.6 0.43 8.4 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 GAO89558.1 - 0.92 8.7 7.5 1.4 8.0 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 GAO89558.1 - 2 8.3 9.2 3.5 7.6 6.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 GAO89558.1 - 5.2 6.2 19.1 8.2 5.5 13.2 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 GAO89558.1 - 7.9 4.8 19.6 11 4.3 13.6 1.2 1 0 0 1 1 1 0 Daxx Family VHS PF00790.14 GAO89559.1 - 1.4e-43 147.9 0.0 5.1e-43 146.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 GAO89559.1 - 7.7e-27 93.2 0.6 2.6e-26 91.5 0.4 1.9 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 GAO89559.1 - 1e-22 80.6 0.1 2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Mei5 PF10376.4 GAO89559.1 - 0.11 12.0 4.0 0.11 12.0 1.8 1.7 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF349 PF03993.7 GAO89559.1 - 0.91 9.7 6.2 0.14 12.3 0.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) CBS PF00571.23 GAO89561.1 - 3.1e-24 84.4 1.6 1.1e-06 28.3 0.0 5.5 5 0 0 5 5 5 5 CBS domain DUF2183 PF09949.4 GAO89562.1 - 3.1e-29 100.8 0.0 7.6e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) ADH_zinc_N_2 PF13602.1 GAO89563.1 - 0.00017 22.4 0.0 0.00036 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GPP34 PF05719.6 GAO89564.1 - 5.6e-61 206.1 1.5 2.8e-59 200.6 0.2 2.1 2 0 0 2 2 2 2 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 GAO89565.1 - 1.8e-10 40.9 0.2 2.5e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAO89565.1 - 2e-06 27.7 0.1 2.5e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.22 GAO89566.1 - 5.9e-14 50.9 16.4 3.2e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 GAO89566.1 - 2.9e-12 46.7 10.8 4.6e-12 46.1 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAO89566.1 - 1.6e-10 40.5 23.3 2.1e-08 33.7 9.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAO89566.1 - 6e-10 39.2 10.3 1.1e-09 38.4 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAO89566.1 - 1.1e-09 38.0 5.2 6e-05 22.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAO89566.1 - 1.2e-09 38.7 8.4 6.5e-05 23.5 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 GAO89566.1 - 7.1e-09 35.8 2.3 0.00074 19.8 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAO89566.1 - 1.1e-08 35.0 20.2 1.8e-05 24.6 8.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAO89566.1 - 1.2e-07 31.1 14.3 0.0006 19.5 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 GAO89566.1 - 4.5e-07 29.6 12.5 0.00059 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 GAO89566.1 - 6.7e-07 28.9 17.4 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 GAO89566.1 - 7.7e-05 23.0 10.5 0.021 15.2 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 GAO89566.1 - 0.0055 17.2 13.3 0.34 11.5 1.3 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 GAO89566.1 - 0.0093 16.3 15.7 0.3 11.4 3.2 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 GAO89566.1 - 0.02 15.4 17.5 0.041 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 GAO89566.1 - 0.023 14.8 4.7 0.38 10.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_11 PF13247.1 GAO89566.1 - 0.12 12.3 4.4 0.19 11.6 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain SURF6 PF04935.7 GAO89567.1 - 1.3e-52 178.1 37.6 1.3e-52 178.1 26.1 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 GAO89567.1 - 1.1e-22 79.8 0.9 1.1e-22 79.8 0.7 8.4 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Rick_17kDa_Anti PF05433.10 GAO89568.1 - 3.3e-05 23.4 12.7 3.3e-05 23.4 8.8 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Ribosomal_S2 PF00318.15 GAO89569.1 - 1.2e-50 171.7 0.0 2.1e-50 170.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 Glyco_hydro_31 PF01055.21 GAO89570.1 - 6.7e-86 288.8 0.1 1.7e-85 287.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO89570.1 - 1e-14 54.1 0.0 2.8e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF2993 PF11209.3 GAO89570.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) MFS_1 PF07690.11 GAO89571.1 - 9.6e-33 113.3 27.5 3.1e-32 111.6 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO89571.1 - 3e-06 26.2 0.0 5.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 GAO89572.1 - 2.1e-63 210.0 0.9 3.6e-21 74.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.22 GAO89573.1 - 1.1e-35 122.8 2.2 5.7e-35 120.4 1.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAO89573.1 - 1.1e-25 89.5 0.1 3.1e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAO89573.1 - 8.1e-15 54.7 2.1 2.8e-07 30.5 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 GAO89573.1 - 4.2e-10 39.1 0.0 1.3e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 GAO89573.1 - 7e-07 29.2 0.1 1.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO89573.1 - 0.00033 21.1 0.1 0.00093 19.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO89573.1 - 0.0015 17.8 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAO89573.1 - 0.0049 16.1 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit zf-RanBP PF00641.13 GAO89573.1 - 0.014 14.4 6.8 0.027 13.5 4.7 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FeoB_N PF02421.13 GAO89573.1 - 0.024 13.9 0.2 0.097 11.9 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 GAO89573.1 - 0.031 13.7 0.1 0.082 12.3 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 GAO89573.1 - 0.12 12.0 2.4 0.5 10.0 0.7 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 GAO89573.1 - 1.4 8.7 8.0 15 5.3 0.0 3.6 3 1 1 4 4 4 0 Dynamin family HNH PF01844.18 GAO89574.1 - 0.08 12.8 0.7 0.18 11.6 0.5 1.6 1 1 0 1 1 1 0 HNH endonuclease MFS_1 PF07690.11 GAO89575.1 - 8.9e-38 129.8 28.7 8.9e-38 129.8 19.9 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO89575.1 - 8.4e-22 77.2 0.0 1.2e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89575.1 - 7.1e-09 35.4 10.3 1.4e-08 34.4 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase_alk PF04734.8 GAO89577.1 - 2.1e-283 941.3 0.0 2.4e-283 941.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 GAO89578.1 - 3.4e-64 216.3 0.3 3.7e-64 216.2 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) 3Beta_HSD PF01073.14 GAO89579.1 - 1.5e-26 92.7 0.0 1.5e-25 89.4 0.0 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAO89579.1 - 1e-16 61.1 0.0 1.8e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAO89579.1 - 1.2e-11 44.0 0.0 6.6e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAO89579.1 - 1.7e-09 37.9 0.0 1.9e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO89579.1 - 5.9e-09 36.0 0.2 2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO89579.1 - 8.1e-07 28.8 0.8 2.9e-06 27.0 0.1 2.1 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAO89579.1 - 5.8e-05 22.1 0.0 9.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO89579.1 - 0.0016 17.3 0.0 0.007 15.2 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 GAO89579.1 - 0.035 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 GAO89580.1 - 2.9e-38 131.4 34.1 2.9e-38 131.4 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89580.1 - 1.7e-12 46.6 11.9 1.7e-12 46.6 8.2 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO89580.1 - 1.7e-09 36.4 5.2 3e-09 35.6 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Snf7 PF03357.16 GAO89581.1 - 6.6e-32 110.2 22.9 6.6e-32 110.2 15.9 2.0 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.6 GAO89581.1 - 1.5 8.0 10.2 1.2 8.4 6.0 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein CRC_subunit PF08624.5 GAO89582.1 - 2.5e-57 192.6 0.0 3.4e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 GAO89583.1 - 3.4e-71 239.4 0.0 4.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89583.1 - 7.1e-31 107.2 0.0 1.1e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAO89583.1 - 4.5e-14 52.7 1.9 4.5e-14 52.7 1.3 3.2 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAO89583.1 - 4.5e-09 35.6 0.0 7.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 GAO89583.1 - 0.0016 18.2 0.2 0.011 15.5 0.2 2.3 1 1 0 1 1 1 1 C2 domain APH PF01636.18 GAO89583.1 - 0.0023 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAO89583.1 - 0.054 13.0 0.1 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 GAO89583.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 GAO89583.1 - 0.12 11.4 0.1 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU PF00009.22 GAO89585.1 - 1e-56 191.3 0.0 1.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAO89585.1 - 2.6e-36 123.7 0.0 9.2e-36 121.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAO89585.1 - 1.9e-17 63.1 2.0 1.9e-17 63.1 1.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAO89585.1 - 3.4e-06 26.5 0.5 8.4e-06 25.3 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAO89585.1 - 0.002 18.0 0.2 0.0068 16.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAO89585.1 - 0.19 10.4 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit TFIIS_C PF01096.13 GAO89586.1 - 5.9e-20 70.6 2.6 5.9e-20 70.6 1.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAO89586.1 - 1.2e-06 28.0 1.6 1.2e-06 28.0 1.1 3.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 GAO89586.1 - 3.7e-05 23.9 1.2 0.0038 17.4 0.2 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 GAO89586.1 - 0.0017 17.7 2.3 3.2 7.3 0.0 3.4 3 0 0 3 3 3 2 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 GAO89586.1 - 0.004 16.9 6.0 0.06 13.1 0.6 2.6 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAO89586.1 - 0.025 14.0 7.8 0.054 13.0 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain LRV_FeS PF05484.6 GAO89586.1 - 0.03 13.8 0.7 0.087 12.4 0.1 2.0 2 0 0 2 2 2 0 LRV protein FeS4 cluster C1_1 PF00130.17 GAO89586.1 - 0.049 13.3 1.1 0.72 9.6 0.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ISL3 PF14690.1 GAO89586.1 - 0.054 13.5 4.1 3.5 7.7 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ogr_Delta PF04606.7 GAO89586.1 - 0.074 12.7 1.7 0.7 9.6 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger NOB1_Zn_bind PF08772.6 GAO89586.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like ROKNT PF08067.6 GAO89586.1 - 0.12 12.2 0.3 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 ROKNT (NUC014) domain TF_Zn_Ribbon PF08271.7 GAO89586.1 - 0.14 11.5 4.0 2 7.8 0.1 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-HYPF PF07503.7 GAO89586.1 - 0.14 11.5 2.2 4.4 6.8 0.2 2.8 2 0 0 2 2 2 0 HypF finger IBR PF01485.16 GAO89586.1 - 0.17 11.7 8.2 3.8 7.4 0.5 3.0 1 1 1 2 2 2 0 IBR domain Elf1 PF05129.8 GAO89586.1 - 0.18 11.5 3.8 11 5.8 0.2 2.9 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 GAO89586.1 - 0.22 11.1 7.3 2 8.0 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 GAO89586.1 - 0.24 11.2 8.3 0.14 11.9 0.8 2.6 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 GAO89586.1 - 0.4 10.4 8.1 2.3 7.9 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 GAO89586.1 - 0.47 9.7 13.2 0.37 10.0 3.7 3.2 3 1 0 3 3 3 0 zinc-ribbon domain zf-C3HC PF07967.8 GAO89586.1 - 1.1 8.9 4.4 2.4 7.9 0.2 2.5 1 1 2 3 3 3 0 C3HC zinc finger-like Nudix_N_2 PF14803.1 GAO89586.1 - 1.5 8.5 9.6 2.8 7.7 2.9 3.1 2 1 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.6 GAO89586.1 - 1.7 8.2 6.1 0.96 9.0 0.1 2.7 3 0 0 3 3 2 0 NADH pyrophosphatase zinc ribbon domain zf-IS66 PF13005.2 GAO89586.1 - 1.8 8.5 0.0 1.8 8.5 0.0 3.4 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 PhnA_Zn_Ribbon PF08274.7 GAO89586.1 - 3.1 7.6 5.8 7 6.5 0.0 2.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon GFA PF04828.9 GAO89586.1 - 4 7.4 7.4 2.2 8.2 0.1 2.9 1 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-AN1 PF01428.11 GAO89586.1 - 4.5 7.2 8.6 3.5 7.5 0.1 3.4 4 0 0 4 4 4 0 AN1-like Zinc finger Rubredoxin PF00301.15 GAO89586.1 - 5.2 7.0 7.5 34 4.4 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin Ank_2 PF12796.2 GAO89587.1 - 4.4e-18 65.4 0.1 3.3e-09 36.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO89587.1 - 7e-10 38.1 0.0 0.00062 19.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAO89587.1 - 2.8e-09 36.9 0.1 0.0008 19.5 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAO89587.1 - 5.4e-09 35.4 0.0 0.00015 21.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAO89587.1 - 1.4e-06 28.6 0.5 0.00064 20.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) MAGE PF01454.14 GAO89588.1 - 2.8e-48 163.8 0.0 3.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 MAGE family Ribosomal_L27e PF01777.13 GAO89589.1 - 4.3e-36 122.9 2.3 7e-36 122.2 1.6 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family TRAM_LAG1_CLN8 PF03798.11 GAO89590.1 - 4.2e-51 173.3 19.0 6e-51 172.8 13.2 1.2 1 0 0 1 1 1 1 TLC domain SWIB PF02201.13 GAO89591.1 - 3.4e-15 55.4 0.0 6.4e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PCI PF01399.22 GAO89592.1 - 1.8e-21 76.3 1.1 4.8e-21 75.0 0.1 2.2 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.1 GAO89592.1 - 2.8e-05 23.9 16.5 0.53 10.2 2.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat DDRGK PF09756.4 GAO89592.1 - 7.2e-05 22.2 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain HTH_Crp_2 PF13545.1 GAO89592.1 - 0.0053 16.5 0.1 1.4 8.7 0.1 3.2 3 1 1 4 4 4 1 Crp-like helix-turn-helix domain TPR_8 PF13181.1 GAO89592.1 - 0.027 14.2 12.6 9.3 6.2 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Soyouz_module PF14313.1 GAO89592.1 - 0.071 12.6 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PCI_Csn8 PF10075.4 GAO89592.1 - 0.077 12.7 1.1 0.18 11.5 0.3 1.9 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_16 PF13432.1 GAO89592.1 - 0.11 13.1 10.9 3.1 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89592.1 - 0.13 12.2 8.7 7.3 6.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAO89592.1 - 0.17 11.5 7.2 1.6 8.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89592.1 - 0.42 11.3 10.0 20 6.1 0.2 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 GAO89592.1 - 1.2 8.9 5.5 0.35 10.6 0.6 2.5 3 0 0 3 3 3 0 Prefoldin subunit TPR_21 PF09976.4 GAO89592.1 - 3.3 7.6 11.1 0.27 11.1 1.6 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 GAO89593.1 - 1.5e-35 119.7 7.3 2.3e-08 33.5 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 GAO89593.1 - 1.6e-31 108.1 11.6 3.6e-31 107.0 8.0 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 GAO89593.1 - 0.0062 16.2 0.2 0.024 14.3 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 GAO89594.1 - 3.6e-30 105.0 0.5 5.2e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89594.1 - 2.1e-15 57.1 0.0 3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89594.1 - 9.2e-10 38.4 0.6 2e-09 37.3 0.4 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAO89594.1 - 0.00021 20.5 0.1 0.00046 19.4 0.1 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAO89594.1 - 0.091 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Amidohydro_4 PF13147.1 GAO89595.1 - 0.049 13.6 0.8 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase PHD PF00628.24 GAO89596.1 - 1.4e-08 34.2 10.3 2.6e-08 33.4 7.2 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 GAO89596.1 - 0.019 14.6 3.6 0.019 14.6 2.5 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 GAO89596.1 - 0.036 13.3 8.2 0.16 11.2 5.7 2.1 1 1 0 1 1 1 0 PHD-finger PBP1_TM PF14812.1 GAO89596.1 - 0.91 9.8 9.5 2.1 8.7 2.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-PHD-like PF15446.1 GAO89596.1 - 3.1 7.0 13.1 0.15 11.3 4.4 2.1 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CoA_transf_3 PF02515.12 GAO89597.1 - 2.6e-58 196.4 0.1 3.9e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 GAO89598.1 - 2.5e-35 120.2 0.0 2e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 GAO89599.1 - 2.5e-53 180.5 0.0 6.4e-53 179.2 0.0 1.6 1 1 0 1 1 1 1 Brix domain DEAD PF00270.24 GAO89600.1 - 1e-48 165.0 0.0 1.7e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89600.1 - 5.2e-25 87.1 0.0 1.3e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89600.1 - 4.8e-05 23.2 0.0 0.00018 21.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PGM_PMM_I PF02878.11 GAO89601.1 - 2.9e-16 59.1 0.1 2.3e-07 30.3 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAO89601.1 - 5.8e-16 58.6 0.2 3.9e-15 56.0 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAO89601.1 - 2.4e-11 43.4 0.7 7.3e-11 41.9 0.2 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 GAO89601.1 - 0.0095 15.9 0.1 0.036 14.1 0.1 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III TauD PF02668.11 GAO89602.1 - 2.1e-42 145.6 0.2 3.3e-42 144.9 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_31 PF13847.1 GAO89602.1 - 3.9e-13 49.2 0.0 7.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO89602.1 - 3.6e-11 43.6 0.0 9.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO89602.1 - 9.3e-11 41.3 0.0 1.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAO89602.1 - 5.2e-10 39.3 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO89602.1 - 1.6e-09 38.0 0.0 4.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 GAO89602.1 - 3.9e-07 29.3 0.0 5.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 GAO89602.1 - 6.3e-06 26.0 0.0 2.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAO89602.1 - 9.5e-06 25.0 0.2 5.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 GAO89602.1 - 1.1e-05 24.2 0.0 1.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 GAO89602.1 - 2.9e-05 24.3 0.0 0.00011 22.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO89602.1 - 0.00013 22.3 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAO89602.1 - 0.0005 19.2 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 GAO89602.1 - 0.0017 18.4 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 GAO89602.1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAO89602.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase 2OG-FeII_Oxy_3 PF13640.1 GAO89602.1 - 0.007 16.8 0.1 0.17 12.4 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_24 PF13578.1 GAO89602.1 - 0.014 16.2 0.0 0.15 12.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAO89602.1 - 0.032 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 GAO89602.1 - 0.082 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein PCMT PF01135.14 GAO89602.1 - 0.1 12.1 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 GAO89602.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB DUF4407 PF14362.1 GAO89602.1 - 0.57 9.0 2.6 0.84 8.5 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.24 GAO89603.1 - 1.3e-40 138.6 0.0 2.3e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO89603.1 - 3.8e-05 22.8 0.0 0.00012 21.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAO89603.1 - 0.00011 21.8 0.1 0.00066 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO89603.1 - 0.00042 20.3 0.3 0.019 14.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAO89603.1 - 0.001 19.0 0.0 0.0098 15.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAO89603.1 - 0.0018 17.2 0.0 0.0049 15.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 GAO89603.1 - 0.0021 17.3 0.1 0.044 13.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 GAO89603.1 - 0.0029 17.7 1.5 0.044 13.9 0.0 2.7 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.16 GAO89603.1 - 0.0053 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAO89603.1 - 0.0093 15.8 0.2 0.032 14.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO89603.1 - 0.013 15.2 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 GAO89603.1 - 0.016 15.0 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAO89603.1 - 0.025 14.0 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAO89603.1 - 0.031 13.3 1.1 0.085 11.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 GAO89603.1 - 0.048 14.4 0.1 0.048 14.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAO89603.1 - 0.05 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAO89603.1 - 0.25 10.7 3.8 0.43 9.9 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.1 GAO89603.1 - 0.79 9.2 0.0 0.79 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain F-box-like PF12937.2 GAO89604.1 - 9e-05 22.1 0.2 0.00028 20.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF4027 PF13219.1 GAO89604.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) PALP PF00291.20 GAO89605.1 - 5.4e-55 186.7 0.0 6.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_hydro_28 PF00295.12 GAO89606.1 - 3.1e-27 95.3 0.2 6.6e-27 94.3 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Bac_rhamnosid PF05592.6 GAO89607.1 - 1.2e-36 126.0 7.8 2.2e-30 105.3 4.8 2.4 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 GAO89607.1 - 0.0002 20.1 0.1 0.00031 19.5 0.1 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 GAO89607.1 - 0.02 13.6 9.3 0.06 12.0 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF608 IBR PF01485.16 GAO89608.1 - 2.7e-09 36.7 55.8 2.3e-08 33.8 1.9 5.0 5 1 0 5 5 5 3 IBR domain Nop25 PF09805.4 GAO89608.1 - 2.5 8.1 8.0 4.1 7.4 5.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Chalcone PF02431.10 GAO89609.1 - 1e-70 237.1 0.0 1.3e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 GAO89610.1 - 1.6e-19 69.6 0.0 2.2e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 GAO89610.1 - 0.0026 17.9 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 GAO89610.1 - 0.0076 16.4 0.2 0.01 16.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 GAO89610.1 - 0.02 14.4 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 GAO89610.1 - 0.03 13.8 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DSBA PF01323.15 GAO89610.1 - 0.031 13.8 0.1 0.076 12.5 0.1 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain GAS PF13851.1 GAO89610.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding THF_DHG_CYH PF00763.18 GAO89610.1 - 0.12 12.3 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Thioredoxin_7 PF13899.1 GAO89610.1 - 0.13 12.3 0.1 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like BAG PF02179.11 GAO89612.1 - 4.5e-17 61.9 0.0 9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 GAO89612.1 - 0.0054 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family LMBR1 PF04791.11 GAO89613.1 - 3e-29 101.9 3.8 3.9e-29 101.5 2.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.7 GAO89613.1 - 1.2e-05 23.9 12.9 2e-05 23.2 2.4 2.2 2 0 0 2 2 2 2 Fusaric acid resistance protein family Med15_fungi PF05397.7 GAO89614.1 - 2.5e-41 140.2 0.0 2.5e-41 140.2 0.0 4.6 4 0 0 4 4 4 1 Mediator complex subunit 15 Nuc_sug_transp PF04142.10 GAO89615.1 - 1.3e-08 34.2 1.9 2.3e-08 33.4 1.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAO89615.1 - 3.3e-06 26.2 11.9 8.5e-06 24.8 2.5 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 GAO89615.1 - 2e-05 24.6 28.9 0.00026 21.0 5.8 3.9 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 GAO89615.1 - 0.00047 19.8 18.9 0.051 13.2 0.7 3.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family MBOAT PF03062.14 GAO89616.1 - 1.4e-39 136.1 23.4 1.4e-39 136.1 16.2 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF3671 PF12420.3 GAO89616.1 - 9.1 6.3 9.2 0.35 10.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function Adaptin_N PF01602.15 GAO89617.1 - 8.3e-142 473.1 1.3 9.8e-142 472.9 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 GAO89617.1 - 5e-20 71.9 0.0 1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 GAO89617.1 - 5.2e-07 29.8 2.1 0.061 13.6 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 GAO89617.1 - 0.0015 18.9 0.6 6.3 7.4 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 GAO89617.1 - 0.0026 17.7 2.2 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 GAO89617.1 - 0.0033 17.3 2.2 0.028 14.2 0.3 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 GAO89617.1 - 0.004 16.7 0.6 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 GAO89617.1 - 0.013 15.2 0.1 31 4.5 0.1 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DnaJ PF00226.26 GAO89618.1 - 3.4e-24 84.3 1.2 7.5e-24 83.2 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 GAO89619.1 - 5.3e-08 32.4 0.2 1.3e-06 27.9 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAO89619.1 - 0.00012 21.9 0.0 0.00044 20.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L13 PF00572.13 GAO89620.1 - 2.8e-28 98.5 0.0 5.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 GAO89621.1 - 1.5e-71 241.0 0.1 1.8e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO89621.1 - 1.5e-16 61.0 0.2 3.7e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 GAO89622.1 - 1.2e-12 47.2 0.4 1.2e-12 47.2 0.3 2.2 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 GAO89622.1 - 8.5e-12 44.6 11.3 0.09 12.5 0.0 7.0 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 GAO89622.1 - 1.1e-10 40.8 11.2 0.15 11.6 0.0 7.4 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAO89622.1 - 3.2e-09 35.8 13.4 3 8.1 0.0 10.5 13 0 0 13 13 13 3 Leucine Rich repeat F-box PF00646.28 GAO89622.1 - 1.3e-05 24.7 0.5 1.3e-05 24.7 0.4 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 GAO89622.1 - 0.0024 17.6 26.3 9.9 6.6 0.1 10.3 8 3 1 9 9 9 1 Leucine Rich Repeat DUF1699 PF08004.6 GAO89622.1 - 0.057 12.9 1.7 0.37 10.3 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) Peptidase_M28 PF04389.12 GAO89623.1 - 2.6e-30 105.4 0.0 4e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAO89623.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt_8 PF00895.15 GAO89623.1 - 0.11 12.6 0.1 0.11 12.6 0.1 4.3 6 1 1 7 7 7 0 ATP synthase protein 8 DUF3304 PF11745.3 GAO89623.1 - 0.13 12.4 0.1 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) Med10 PF09748.4 GAO89625.1 - 7.4e-43 145.4 0.4 1e-42 144.9 0.3 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex SERTA PF06031.8 GAO89625.1 - 0.04 13.2 0.1 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 SERTA motif FliL PF03748.9 GAO89625.1 - 0.1 12.5 0.8 6 6.9 0.1 3.1 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL Pkinase PF00069.20 GAO89626.1 - 1.7e-40 138.8 0.0 2.7e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89626.1 - 1.1e-29 103.2 0.0 1.5e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO89626.1 - 0.00094 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO89626.1 - 0.0089 15.7 0.1 2 8.0 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Myco_19_kDa PF05481.7 GAO89628.1 - 0.0037 17.1 0.0 0.0037 17.1 0.0 1.7 2 0 0 2 2 2 1 Mycobacterium 19 kDa lipoprotein antigen Nucleoplasmin PF03066.10 GAO89628.1 - 0.0058 16.1 4.6 0.01 15.3 3.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin DUF4098 PF13345.1 GAO89628.1 - 0.006 16.5 0.0 22 5.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4098) Herpes_gE PF02480.11 GAO89628.1 - 0.073 11.3 0.0 0.073 11.3 0.0 2.2 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Sigma70_ner PF04546.8 GAO89628.1 - 0.42 10.2 4.1 0.66 9.5 2.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 GAO89628.1 - 1.5 7.4 10.2 2.7 6.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 GAO89628.1 - 2.6 7.2 5.7 4.2 6.5 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 GAO89628.1 - 3.5 7.9 13.9 13 6.1 7.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 GAO89628.1 - 4.8 7.4 12.8 10 6.4 8.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_11 PF13414.1 GAO89629.1 - 9.1e-53 175.8 39.2 1.1e-20 73.0 1.5 5.6 3 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAO89629.1 - 2.7e-42 140.7 19.0 2e-08 33.5 1.2 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89629.1 - 4.9e-39 129.0 18.4 1.2e-06 28.0 0.3 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAO89629.1 - 1.1e-30 105.6 16.2 3e-08 34.1 3.0 6.0 3 3 3 6 6 6 6 Tetratricopeptide repeat DnaJ PF00226.26 GAO89629.1 - 1.5e-28 98.3 2.2 1.5e-28 98.3 1.5 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_19 PF14559.1 GAO89629.1 - 1.8e-24 85.8 24.4 4.3e-09 36.5 0.4 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89629.1 - 4.3e-21 73.5 15.7 0.0011 19.3 0.1 8.1 4 3 3 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 GAO89629.1 - 2.1e-20 72.6 6.4 1e-08 35.2 0.0 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAO89629.1 - 6.8e-19 66.1 20.1 6.5e-06 25.5 1.0 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAO89629.1 - 8.4e-18 64.0 18.0 6.9e-07 29.1 0.7 5.5 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO89629.1 - 8.9e-18 62.9 18.4 1.6e-05 24.7 0.0 6.7 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAO89629.1 - 8.9e-14 51.0 7.3 8.3e-05 22.3 1.6 4.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAO89629.1 - 1.6e-12 46.1 10.0 2.2 8.3 0.1 7.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAO89629.1 - 9.2e-12 44.6 11.2 0.0087 15.9 0.0 5.3 5 0 0 5 5 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 GAO89629.1 - 1.1e-11 44.3 6.7 0.00058 19.0 0.1 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAO89629.1 - 4.4e-10 39.3 20.1 0.055 13.9 0.1 8.4 9 0 0 9 9 7 3 Tetratricopeptide repeat BTAD PF03704.12 GAO89629.1 - 2.1e-06 28.1 7.0 0.0063 16.8 0.0 3.9 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_20 PF14561.1 GAO89629.1 - 6.1e-06 26.2 8.7 0.018 15.1 0.1 4.8 3 2 2 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAO89629.1 - 1.3e-05 25.5 5.0 1.1 9.5 0.0 4.3 2 1 3 5 5 5 2 Alkyl sulfatase dimerisation ChAPs PF09295.5 GAO89629.1 - 1.4e-05 24.1 2.6 0.064 12.0 0.0 3.0 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.4 GAO89629.1 - 0.00032 19.8 6.0 0.78 9.0 0.4 5.0 6 0 0 6 6 6 2 SHNi-TPR TPR_4 PF07721.9 GAO89629.1 - 0.0021 18.3 11.5 0.98 10.0 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat DUF1039 PF06287.6 GAO89629.1 - 0.0085 15.9 0.0 5.3 7.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1039) TPR_21 PF09976.4 GAO89629.1 - 0.046 13.6 0.1 0.046 13.6 0.1 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 GAO89629.1 - 0.061 13.1 0.5 0.39 10.5 0.1 2.5 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.13 GAO89629.1 - 0.067 13.0 11.7 3.8 7.4 0.1 5.7 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain Dynamin_N PF00350.18 GAO89630.1 - 5.7e-07 29.5 0.0 1.1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAO89630.1 - 2.9e-05 24.0 0.1 0.0011 18.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAO89630.1 - 0.00019 20.6 0.1 0.0083 15.3 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 GAO89630.1 - 0.00039 20.1 0.1 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 GAO89630.1 - 0.0026 18.0 0.2 0.0071 16.6 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 GAO89630.1 - 0.0035 16.9 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase cobW PF02492.14 GAO89630.1 - 0.014 14.8 0.1 0.13 11.7 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 GAO89630.1 - 0.017 14.1 0.7 0.056 12.5 0.0 2.2 2 1 0 3 3 3 0 Zeta toxin Miro PF08477.8 GAO89630.1 - 0.021 15.3 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein KAP_NTPase PF07693.9 GAO89630.1 - 0.023 13.6 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.1 GAO89630.1 - 0.026 14.5 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 GAO89630.1 - 0.055 13.2 0.3 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Scs3p PF10261.4 GAO89631.1 - 6.6e-74 247.9 4.3 8.4e-74 247.5 3.0 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.9 GAO89633.1 - 7.1e-146 485.8 2.2 8.3e-146 485.6 1.5 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF3535 PF12054.3 GAO89635.1 - 3.6e-155 516.9 0.0 1.9e-154 514.5 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 GAO89635.1 - 1.5e-71 240.6 0.0 2.2e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 GAO89635.1 - 5.6e-17 60.2 19.4 0.046 13.8 0.0 11.1 12 0 0 12 12 12 6 HEAT repeat Helicase_C PF00271.26 GAO89635.1 - 3.5e-14 52.3 0.0 8.9e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 GAO89635.1 - 8.6e-09 35.5 17.4 0.0023 18.1 0.1 8.1 7 2 0 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.2 GAO89635.1 - 2.1e-08 34.4 0.1 0.084 13.2 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAO89635.1 - 3e-05 24.3 18.9 0.57 10.7 0.0 9.2 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.2 GAO89635.1 - 0.0015 18.4 0.8 1.7 8.4 0.1 5.1 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 GAO89635.1 - 0.0019 17.5 1.1 0.54 9.5 0.0 3.7 2 2 1 3 3 3 1 CLASP N terminal HEAT_PBS PF03130.11 GAO89635.1 - 3.3 8.4 10.9 12 6.7 0.0 5.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Ndufs5 PF10200.4 GAO89636.1 - 0.0002 21.3 0.1 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 GAO89636.1 - 0.004 17.2 0.8 0.0061 16.6 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 GAO89636.1 - 0.024 14.6 0.3 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 GAO89636.1 - 0.15 11.9 0.5 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 CHCH domain Sec39 PF08314.6 GAO89637.1 - 2.1e-273 908.5 1.5 2.4e-273 908.4 1.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.20 GAO89638.1 - 2.6e-62 210.3 0.0 3.2e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO89638.1 - 7.8e-37 126.7 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO89638.1 - 1.9e-09 36.9 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAO89638.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_3 PF00933.16 GAO89641.1 - 8.7e-91 304.0 0.0 1.4e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO89641.1 - 1.3e-57 194.9 2.0 1.4e-56 191.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO89641.1 - 6.8e-16 57.9 0.1 1.4e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SBF PF01758.11 GAO89642.1 - 1.4e-47 161.5 9.1 1.4e-47 161.5 6.3 2.2 4 0 0 4 4 4 1 Sodium Bile acid symporter family Dynactin PF12455.3 GAO89643.1 - 0.0012 17.8 0.5 0.0016 17.3 0.3 1.2 1 0 0 1 1 1 1 Dynein associated protein bZIP_1 PF00170.16 GAO89643.1 - 0.015 15.2 9.9 0.015 15.2 6.8 2.2 2 1 1 3 3 3 0 bZIP transcription factor Fungal_trans PF04082.13 GAO89644.1 - 1.1e-25 90.0 0.0 1.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89644.1 - 4.9e-09 35.9 12.1 8.2e-09 35.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.10 GAO89645.1 - 8.9e-10 38.0 0.1 1.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 GAO89645.1 - 9.8e-08 31.8 0.2 0.0054 16.5 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 GAO89645.1 - 0.00041 19.6 0.0 0.0014 17.9 0.0 1.7 2 1 0 2 2 2 1 Autophagy-related protein 27 ERG4_ERG24 PF01222.12 GAO89646.1 - 3.7e-160 533.1 5.2 4.2e-160 532.9 3.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAO89646.1 - 0.00043 19.6 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Vps55 PF04133.9 GAO89646.1 - 0.023 14.4 3.0 0.083 12.6 2.1 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 55 A_deamin PF02137.13 GAO89647.1 - 3.7e-43 148.1 0.0 9.3e-43 146.8 0.0 1.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SF3b10 PF07189.6 GAO89648.1 - 1.1e-35 121.3 0.0 1.2e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.3 GAO89649.1 - 7.9e-72 240.7 0.1 7.9e-72 240.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) HALZ PF02183.13 GAO89649.1 - 0.0071 16.0 1.4 0.0071 16.0 1.0 3.0 2 1 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 GAO89649.1 - 0.013 15.4 5.8 0.013 15.4 4.0 2.7 2 1 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 GAO89649.1 - 0.022 14.3 18.7 0.057 13.0 7.8 2.4 2 0 0 2 2 2 0 IncA protein START PF01852.14 GAO89649.1 - 0.023 14.0 0.3 2.4 7.4 0.0 2.7 2 1 0 2 2 2 0 START domain DUF4618 PF15397.1 GAO89649.1 - 0.13 11.5 12.5 0.35 10.1 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.6 GAO89649.1 - 0.6 10.0 4.2 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 GAO89649.1 - 3.8 6.6 13.7 5.3 6.2 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.10 GAO89649.1 - 8.9 5.8 13.7 4.4 6.8 2.4 3.1 2 1 0 2 2 2 0 Septum formation initiator Adaptin_N PF01602.15 GAO89651.1 - 0.0092 14.3 0.0 0.12 10.6 0.0 2.3 2 1 0 2 2 2 1 Adaptin N terminal region NUC130_3NT PF08158.7 GAO89651.1 - 0.066 13.5 15.6 32 4.9 0.0 8.7 7 4 3 11 11 11 0 NUC130/3NT domain DUF4122 PF13498.1 GAO89651.1 - 0.08 12.3 0.6 47 3.2 0.0 4.6 5 1 0 5 5 5 0 Domain of unknown function (DUF4122) ApoB100_C PF12491.3 GAO89651.1 - 0.16 11.6 0.1 1.6e+02 2.0 0.0 4.5 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal Herpes_TAF50 PF03326.8 GAO89651.1 - 1.6 7.5 23.7 3 6.6 16.4 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Peptidase_S64 PF08192.6 GAO89651.1 - 7.2 4.8 8.3 9.7 4.3 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 PhaP_Bmeg PF09602.5 GAO89652.1 - 0.022 14.6 2.5 0.027 14.2 1.8 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Gon7 PF08738.5 GAO89652.1 - 0.03 14.3 0.9 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 Gon7 family Flagellin_C PF00700.16 GAO89652.1 - 0.041 14.0 0.3 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF2229 PF09989.4 GAO89652.1 - 0.066 12.6 0.1 0.076 12.4 0.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Borrelia_P83 PF05262.6 GAO89652.1 - 0.086 11.0 5.9 0.098 10.9 4.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein APG6 PF04111.7 GAO89652.1 - 0.18 10.7 2.3 0.21 10.5 1.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PRKCSH-like PF12999.2 GAO89652.1 - 0.19 11.3 1.7 0.25 10.9 1.2 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Nop25 PF09805.4 GAO89652.1 - 0.5 10.4 12.5 0.69 9.9 8.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Bap31 PF05529.7 GAO89652.1 - 1.9 7.8 5.1 2.4 7.5 3.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NT-C2 PF10358.4 GAO89653.1 - 3.7e-34 117.2 0.0 5e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 GAO89654.1 - 4.9e-65 218.8 0.0 1.2e-64 217.5 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator PTP_N PF12453.3 GAO89654.1 - 0.088 12.4 0.6 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Myotub-related PF06602.9 GAO89655.1 - 4.2e-124 413.8 0.0 6.4e-124 413.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAO89655.1 - 0.0016 18.6 0.3 0.0059 16.8 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family HD_assoc PF13286.1 GAO89655.1 - 0.014 15.6 0.1 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Y_phosphatase PF00102.22 GAO89655.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 GAO89656.1 - 7.8e-17 61.2 0.1 1.6e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 GAO89656.1 - 2.7e-12 46.0 0.1 4.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 GAO89656.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 GAO89657.1 - 3.4e-25 88.5 0.0 6.4e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 GAO89657.1 - 2.1e-19 69.0 0.0 5.5e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 GAO89657.1 - 0.055 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein HEAT PF02985.17 GAO89658.1 - 5.6e-43 141.1 15.1 0.0028 17.5 0.1 13.1 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 GAO89658.1 - 1.4e-34 118.1 0.4 1.2e-08 35.1 0.0 7.9 2 2 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 GAO89658.1 - 4.8e-12 46.1 2.7 0.002 18.4 0.0 7.2 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAO89658.1 - 5.6e-12 45.7 6.5 0.022 15.2 0.0 9.4 8 2 3 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 GAO89658.1 - 6e-09 34.7 2.3 3.3e-06 25.7 0.1 3.8 2 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 GAO89658.1 - 0.0025 17.2 0.8 0.23 10.7 0.1 3.9 3 2 2 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 GAO89658.1 - 0.018 14.8 4.2 0.32 10.8 0.1 4.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAO89658.1 - 5 7.1 9.9 12 5.8 0.0 5.5 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Glyco_transf_90 PF05686.7 GAO89659.1 - 2e-16 59.6 8.4 2.1e-13 49.7 4.5 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 GAO89660.1 - 7.9e-22 78.2 0.1 6.8e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO89660.1 - 1.5e-09 37.8 0.0 3.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO89660.1 - 9.1e-07 28.7 0.0 1.9e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_8 PF01501.15 GAO89661.1 - 6.8e-34 117.3 0.2 1.9e-33 115.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 GAO89661.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 GAO89661.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative CDO_I PF05995.7 GAO89662.1 - 1.5e-21 76.3 0.1 1.5e-14 53.5 0.1 2.1 1 1 1 2 2 2 2 Cysteine dioxygenase type I TGS PF02824.16 GAO89663.1 - 2e-19 69.1 0.0 7.1e-19 67.3 0.0 1.9 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 GAO89663.1 - 2.2e-18 66.3 0.2 5.6e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO89663.1 - 8.2e-10 38.1 0.1 5.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAO89663.1 - 5.1e-05 22.7 0.2 0.5 9.7 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAO89663.1 - 0.00054 19.8 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin family ArgK PF03308.11 GAO89663.1 - 0.0056 15.5 0.1 0.013 14.2 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 GAO89663.1 - 0.024 15.1 0.1 0.076 13.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 GAO89663.1 - 0.14 12.0 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.11 GAO89664.1 - 1.6e-16 59.8 0.0 3.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 GAO89664.1 - 0.00011 21.5 0.1 0.0003 20.1 0.1 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 GAO89664.1 - 0.0043 16.5 0.2 0.012 15.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 GAO89664.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 GAO89664.1 - 0.038 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 GAO89664.1 - 0.052 13.2 0.2 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.7 GAO89664.1 - 0.076 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain Sigma70_r4 PF04545.11 GAO89664.1 - 0.099 11.9 0.8 0.23 10.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.1 GAO89664.1 - 0.11 12.4 0.7 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 GAO89664.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PXA PF02194.10 GAO89665.1 - 3.8e-44 150.4 0.1 8.2e-44 149.3 0.1 1.6 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.14 GAO89666.1 - 1.2e-50 172.5 0.0 1.4e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MR_MLE_C PF13378.1 GAO89667.1 - 2.2e-33 114.5 0.0 4e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAO89667.1 - 2.7e-18 66.0 0.0 5.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 GAO89667.1 - 1.2e-09 38.5 0.0 2.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Vac_ImportDeg PF09783.4 GAO89668.1 - 1.6e-48 164.5 0.3 1.4e-47 161.4 0.3 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein Ribosomal_L7Ae PF01248.21 GAO89669.1 - 1.7e-27 94.7 0.7 2.1e-27 94.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 GAO89669.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 GAO89670.1 - 1.8e-27 95.4 0.1 9.2e-19 67.5 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAO89670.1 - 2e-22 78.6 0.4 8e-10 38.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 GAO89670.1 - 2.7e-22 77.3 0.7 7.1e-07 28.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 GAO89670.1 - 1.8e-15 55.4 0.0 6.8e-05 22.7 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAO89670.1 - 4.3e-15 55.7 0.2 2.4e-09 37.4 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) V_ATPase_I PF01496.14 GAO89670.1 - 9.7 3.8 7.5 15 3.2 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Steroid_dh PF02544.11 GAO89671.1 - 5.5e-14 52.1 1.6 7e-14 51.8 0.2 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FA_desaturase PF00487.19 GAO89671.1 - 0.068 12.6 13.7 0.27 10.6 5.8 2.2 2 0 0 2 2 2 0 Fatty acid desaturase 2OG-FeII_Oxy_2 PF13532.1 GAO89672.1 - 5.2e-12 46.0 0.0 3.2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAO89672.1 - 0.0027 17.9 0.0 0.0058 16.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.1 GAO89673.1 - 1.5e-17 63.8 0.0 2.5e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 GAO89673.1 - 3.4e-16 59.7 0.0 5.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 GAO89673.1 - 2.6e-05 24.8 0.0 3.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.6 GAO89674.1 - 1.5e-72 244.0 9.4 5.9e-72 242.1 6.5 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 GAO89674.1 - 9.3e-07 28.1 1.7 0.014 14.4 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 GAO89674.1 - 2.7e-06 27.4 7.8 2.7e-06 27.4 5.4 3.2 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAO89674.1 - 0.00042 20.4 17.3 0.0031 17.7 1.6 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 GAO89674.1 - 0.0095 15.5 8.6 0.0095 15.5 5.9 3.0 3 1 0 3 3 3 1 Triose-phosphate Transporter family Sen15 PF09631.5 GAO89675.1 - 4.9e-17 62.0 0.0 3.8e-16 59.1 0.0 2.2 1 1 0 1 1 1 1 Sen15 protein DUF1436 PF07262.6 GAO89675.1 - 0.13 11.7 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) PH PF00169.24 GAO89676.1 - 2.1e-09 37.5 0.0 5.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 GAO89676.1 - 0.00011 21.6 0.0 0.0003 20.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 GAO89676.1 - 0.02 15.1 5.9 3.4 7.9 0.1 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Kri1_C PF12936.2 GAO89677.1 - 5.7e-33 112.7 0.3 5.7e-33 112.7 0.2 4.3 3 2 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 GAO89677.1 - 1.7e-28 98.8 27.2 1.7e-28 98.8 18.8 5.7 5 3 1 6 6 6 1 KRI1-like family CRISPR_Cse2 PF09485.5 GAO89677.1 - 0.0054 16.7 3.1 0.02 14.9 2.1 2.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) Mito_carr PF00153.22 GAO89678.1 - 1.8e-67 223.0 5.6 5.3e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.4 GAO89680.1 - 8.5e-39 131.1 0.0 1.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein CoA_transf_3 PF02515.12 GAO89681.1 - 1.4e-31 109.2 0.1 3.2e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III SnoaL_2 PF12680.2 GAO89682.1 - 0.051 13.9 0.0 0.082 13.3 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Ribosomal_S19e PF01090.14 GAO89683.1 - 5.4e-57 191.1 0.3 6.2e-57 190.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box PF00646.28 GAO89684.1 - 1.2e-08 34.4 0.1 3.2e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO89684.1 - 1.9e-07 30.7 0.4 1.9e-07 30.7 0.3 2.4 3 0 0 3 3 3 1 F-box-like Thioredoxin PF00085.15 GAO89685.1 - 1.3e-33 114.7 0.4 3.5e-26 90.8 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 GAO89685.1 - 4.5e-09 36.3 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAO89685.1 - 1.4e-08 34.9 0.9 0.00085 19.5 0.2 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAO89685.1 - 6.8e-06 26.1 0.1 0.0077 16.3 0.0 3.7 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAO89685.1 - 0.0031 17.2 0.2 0.66 9.8 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 GAO89685.1 - 0.0038 17.2 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 GAO89685.1 - 0.0067 15.9 2.3 1.5 8.2 0.0 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein ERp29_N PF07912.8 GAO89685.1 - 0.013 15.4 0.0 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 ERp29, N-terminal domain AhpC-TSA PF00578.16 GAO89685.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family EutB PF06751.6 GAO89685.1 - 0.035 12.4 0.0 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Calsequestrin PF01216.12 GAO89685.1 - 0.11 11.2 0.1 0.53 8.9 0.0 1.9 1 1 1 2 2 2 0 Calsequestrin GNAT_acetyltr_2 PF13718.1 GAO89686.1 - 5.5e-80 267.3 0.0 9.4e-80 266.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 GAO89686.1 - 1.5e-66 223.3 0.0 4.3e-66 221.9 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 GAO89686.1 - 6.7e-40 134.6 0.0 1.7e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 GAO89686.1 - 3.7e-37 126.4 0.6 9.9e-37 125.1 0.4 1.7 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 GAO89686.1 - 0.0052 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO89686.1 - 0.023 14.7 0.1 0.27 11.2 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family DGF-1_C PF11040.3 GAO89686.1 - 0.31 10.9 1.7 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Glyco_transf_90 PF05686.7 GAO89687.1 - 2e-14 53.1 0.1 1.2e-05 24.2 0.0 3.7 3 1 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_16 PF00722.16 GAO89688.1 - 3.3e-10 39.5 0.0 7.5e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.2 GAO89689.1 - 9.1e-72 240.4 0.0 1.7e-71 239.5 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 GAO89689.1 - 4e-05 23.2 0.0 0.22 11.1 0.0 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 GAO89689.1 - 0.0059 16.4 0.2 0.0059 16.4 0.2 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAO89689.1 - 0.012 15.6 0.1 0.041 13.9 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pox_D3 PF04580.8 GAO89689.1 - 0.034 13.3 0.1 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_5 PF14634.1 GAO89689.1 - 0.16 11.7 3.0 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Toxin_14 PF07829.6 GAO89690.1 - 1.1 9.0 3.5 16 5.3 0.6 2.4 2 0 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein DEAD PF00270.24 GAO89691.1 - 3.8e-18 65.5 0.0 2.7e-17 62.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89691.1 - 4.9e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89691.1 - 4e-05 23.5 0.0 0.00018 21.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 GAO89691.1 - 0.00033 20.7 0.1 0.0017 18.4 0.1 2.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 GAO89691.1 - 0.013 15.6 0.2 0.14 12.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain HTH_45 PF14947.1 GAO89691.1 - 0.023 14.4 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix Sigma70_r4 PF04545.11 GAO89691.1 - 0.054 12.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 zf-HC5HC2H PF13771.1 GAO89692.1 - 5e-22 77.8 1.9 5e-22 77.8 1.3 4.8 4 1 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 GAO89692.1 - 1.9e-21 76.1 0.5 1.9e-21 76.1 0.4 4.2 5 1 0 5 5 5 1 PHD-zinc-finger like domain BAH PF01426.13 GAO89692.1 - 6.5e-15 54.9 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 GAO89692.1 - 1.7e-10 40.3 49.9 1.4e-07 31.0 3.6 5.3 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 GAO89692.1 - 2.6e-08 33.0 7.6 2.6e-08 33.0 5.2 5.1 5 0 0 5 5 5 1 PHD-finger C1_1 PF00130.17 GAO89692.1 - 0.0068 16.1 2.7 0.0068 16.1 1.9 5.9 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 GAO89692.1 - 0.057 13.4 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain PDEase_I PF00233.14 GAO89693.1 - 6.8e-48 163.4 0.0 1e-46 159.5 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase G-gamma PF00631.17 GAO89694.1 - 2.7e-25 87.9 0.0 3.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.3 GAO89694.1 - 0.043 13.7 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) RSS_P20 PF11757.3 GAO89694.1 - 0.085 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PCI PF01399.22 GAO89695.1 - 4.7e-11 42.9 2.9 7.8e-10 39.0 0.0 3.5 3 0 0 3 3 3 1 PCI domain Acetyltransf_1 PF00583.19 GAO89697.1 - 2.1e-10 40.4 0.1 3.2e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAO89697.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAO89697.1 - 0.0032 17.5 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO89697.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 GAO89698.1 - 5e-22 78.0 48.7 2.6e-15 56.0 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.17 GAO89699.1 - 1.2e-24 85.7 0.6 2.1e-24 85.0 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 GAO89700.1 - 3.2e-31 105.7 56.0 0.00012 22.2 0.1 10.9 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89700.1 - 6.9e-25 85.5 57.8 0.0036 17.5 0.0 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO89700.1 - 1.9e-22 78.3 56.5 2.5e-05 24.3 0.8 11.4 11 0 0 11 11 11 8 Zinc-finger double domain GAGA PF09237.6 GAO89700.1 - 0.00058 19.3 4.0 0.00069 19.1 0.3 3.0 3 0 0 3 3 3 1 GAGA factor zf-C2H2_jaz PF12171.3 GAO89700.1 - 0.0058 16.7 24.8 17 5.6 0.0 9.1 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 GAO89700.1 - 0.12 12.6 0.2 0.12 12.6 0.1 9.6 10 0 0 10 10 10 0 C2H2-type zinc-finger domain zf-met PF12874.2 GAO89700.1 - 1.9 8.7 20.3 15 5.9 0.2 7.7 9 0 0 9 9 9 0 Zinc-finger of C2H2 type PH PF00169.24 GAO89702.1 - 1.2e-05 25.4 0.0 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 GAO89702.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain COPIIcoated_ERV PF07970.7 GAO89703.1 - 2.2e-69 233.4 0.0 3.1e-45 154.5 0.0 2.4 3 0 0 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAO89703.1 - 6.8e-35 118.9 0.0 1.7e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 GAO89704.1 - 3.8e-12 45.4 1.3 4.2e-12 45.2 0.2 1.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 GAO89704.1 - 1.4e-08 34.1 0.8 1.4e-05 24.5 0.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 GAO89704.1 - 0.00077 19.8 0.0 0.0024 18.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 GAO89704.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 GAO89704.1 - 0.0029 17.3 0.0 2.2 8.6 0.1 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.1 GAO89704.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.1 GAO89704.1 - 0.028 14.4 0.5 1.5 9.1 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 GAO89704.1 - 0.043 14.0 0.7 2.7 8.5 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat Vps53_N PF04100.7 GAO89705.1 - 1.6e-109 366.2 6.8 2.1e-109 365.8 3.4 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 GAO89705.1 - 9e-08 31.3 8.6 9e-08 31.3 6.0 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 GAO89705.1 - 2.2e-05 24.3 4.8 8.7e-05 22.4 2.8 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 GAO89705.1 - 8.1e-05 21.4 9.6 0.00012 20.8 6.2 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.4 GAO89705.1 - 8.5e-05 22.4 0.3 0.00026 20.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.8 GAO89705.1 - 0.00019 20.1 0.7 0.00019 20.1 0.5 3.2 1 1 1 2 2 2 1 RINT-1 / TIP-1 family Sec8_exocyst PF04048.9 GAO89705.1 - 0.025 14.1 2.6 0.091 12.3 1.8 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Sigma70_ner PF04546.8 GAO89705.1 - 0.026 14.1 8.2 0.21 11.1 4.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Pex19 PF04614.7 GAO89705.1 - 0.033 13.8 5.9 7.6 6.0 0.0 3.5 3 0 0 3 3 3 0 Pex19 protein family V_ATPase_I PF01496.14 GAO89705.1 - 0.059 11.2 3.5 0.1 10.4 2.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 GAO89705.1 - 0.22 11.3 1.6 0.73 9.6 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Ribosomal_L10 PF00466.15 GAO89706.1 - 1.1e-25 89.4 0.1 2.1e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 GAO89706.1 - 3.4e-23 81.8 5.0 3.4e-23 81.8 3.5 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 GAO89707.1 - 2.8e-07 30.1 4.5 8.3e-05 22.3 0.3 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 GAO89707.1 - 0.017 14.5 0.5 0.71 9.2 0.0 3.0 2 1 0 2 2 2 0 PQQ-like domain CPSF_A PF03178.10 GAO89707.1 - 0.065 12.3 0.0 0.38 9.8 0.0 2.3 3 0 0 3 3 3 0 CPSF A subunit region URO-D PF01208.12 GAO89708.1 - 2.1e-123 411.6 0.0 2.4e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.17 GAO89709.1 - 4.7e-24 83.9 0.1 6.4e-24 83.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAO89709.1 - 6.8e-06 25.9 2.0 0.05 13.4 0.5 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 GAO89709.1 - 0.0022 17.7 0.0 0.0048 16.5 0.0 1.5 1 1 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 GAO89709.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DnaJ PF00226.26 GAO89710.1 - 1.2e-25 88.9 2.2 2.2e-25 88.1 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAO89710.1 - 1.6e-23 82.3 0.5 4.4e-20 71.3 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAO89710.1 - 4.2e-14 52.3 17.8 7.6e-14 51.5 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAO89710.1 - 0.13 11.9 9.2 0.12 12.0 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 GAO89710.1 - 0.2 11.4 4.5 4.5 7.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Sulfate_transp PF00916.15 GAO89711.1 - 2.4e-76 256.4 8.9 4.5e-76 255.5 6.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAO89711.1 - 4.4e-31 106.3 4.4 4.4e-31 106.3 3.0 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAO89711.1 - 4.2e-07 29.4 0.0 8.1e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_1 PF07690.11 GAO89712.1 - 4.1e-32 111.2 53.0 4.7e-31 107.7 9.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO89712.1 - 1.1e-14 53.6 10.5 1.1e-14 53.6 7.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SAM_2 PF07647.12 GAO89713.1 - 1.5e-09 37.5 0.1 3.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAO89713.1 - 1.9e-05 24.7 0.5 4e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 GAO89713.1 - 0.021 13.2 4.3 0.099 11.0 0.6 2.2 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 TPR_11 PF13414.1 GAO89714.1 - 3.6e-25 87.3 21.6 5.8e-06 25.8 0.5 7.7 9 1 1 10 10 9 5 TPR repeat TPR_19 PF14559.1 GAO89714.1 - 4.6e-22 78.1 12.8 5.4e-06 26.6 0.0 8.6 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO89714.1 - 7.3e-17 60.1 5.2 0.032 14.4 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89714.1 - 3.9e-16 58.0 16.4 4.5e-05 23.7 0.1 10.2 7 3 4 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAO89714.1 - 7.2e-16 58.3 22.1 4.6e-06 27.1 0.0 8.3 8 1 0 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO89714.1 - 1e-15 57.6 9.9 0.00033 20.7 0.0 6.9 7 1 0 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAO89714.1 - 4.5e-15 54.2 19.8 0.012 15.4 0.0 10.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAO89714.1 - 1e-13 50.0 16.4 0.00022 20.7 0.0 8.6 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAO89714.1 - 4e-12 45.9 21.0 0.00048 19.9 0.5 8.3 8 2 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAO89714.1 - 1.2e-10 40.3 9.9 0.094 12.5 0.0 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO89714.1 - 1.4e-10 40.3 19.9 0.056 13.0 0.1 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAO89714.1 - 1.1e-06 28.6 5.8 0.45 11.0 0.0 7.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAO89714.1 - 0.00039 20.2 1.3 0.051 13.4 0.1 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAO89714.1 - 0.00046 20.4 0.7 0.23 11.7 0.0 3.2 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation ChAPs PF09295.5 GAO89714.1 - 0.00067 18.5 0.0 0.012 14.4 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 GAO89714.1 - 0.001 19.1 6.8 14 5.8 0.0 5.4 3 1 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 GAO89714.1 - 0.0038 16.4 2.8 1.3 8.1 0.0 3.4 4 0 0 4 4 4 2 Soluble NSF attachment protein, SNAP BTAD PF03704.12 GAO89714.1 - 0.056 13.7 0.0 0.056 13.7 0.0 4.0 4 1 1 5 5 5 0 Bacterial transcriptional activator domain NatB_MDM20 PF09797.4 GAO89714.1 - 0.072 11.7 0.1 0.79 8.3 0.0 2.5 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit RPN7 PF10602.4 GAO89714.1 - 0.092 12.1 1.3 26 4.1 0.0 4.0 3 1 1 4 4 4 0 26S proteasome subunit RPN7 CDC45 PF02724.9 GAO89714.1 - 0.29 9.1 3.8 0.46 8.4 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_4 PF07721.9 GAO89714.1 - 0.98 10.0 14.4 9.3 7.0 0.0 6.5 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF3336 PF11815.3 GAO89715.1 - 9e-52 174.4 2.4 1.8e-51 173.4 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAO89715.1 - 9.4e-19 68.1 0.7 1.6e-11 44.5 0.2 2.7 2 1 0 3 3 3 2 Patatin-like phospholipase LRR_4 PF12799.2 GAO89716.1 - 3.1e-16 58.5 8.9 8.4e-06 25.2 0.2 5.6 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO89716.1 - 3.2e-16 58.8 2.6 9.5e-08 31.6 0.4 3.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 GAO89716.1 - 1.3e-08 33.7 7.7 1.3 9.3 0.1 6.7 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 GAO89716.1 - 0.00011 21.9 3.8 1.9 8.7 0.0 5.6 4 1 1 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 GAO89716.1 - 0.064 13.4 15.0 24 5.6 0.2 6.2 6 1 0 6 6 6 0 Leucine rich repeat Metallophos PF00149.23 GAO89717.1 - 6.7e-45 152.9 0.2 8.1e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 GAO89718.1 - 3.2e-66 221.8 0.0 3.6e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAO89718.1 - 4.6e-10 38.7 0.1 1.8e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAO89718.1 - 3.8e-09 36.0 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAO89718.1 - 3.1e-07 30.3 0.0 4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAO89718.1 - 7.2e-07 29.7 0.0 9.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAO89718.1 - 2e-06 27.3 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAO89718.1 - 1.9e-05 23.8 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAO89718.1 - 0.0049 16.3 0.0 0.17 11.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAO89718.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 GAO89718.1 - 0.1 12.0 0.0 6 6.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.4 GAO89719.1 - 2e-177 590.5 31.7 2e-177 590.5 22.0 2.9 2 2 1 3 3 3 1 Protein of unknown function (DUF2457) CH PF00307.26 GAO89720.1 - 5.6e-06 26.3 0.0 0.022 14.8 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain IQ PF00612.22 GAO89720.1 - 0.011 15.2 1.1 0.011 15.2 0.7 3.1 3 0 0 3 3 3 0 IQ calmodulin-binding motif DRIM PF07539.7 GAO89720.1 - 0.044 13.2 0.1 0.17 11.3 0.1 2.0 1 0 0 1 1 1 0 Down-regulated in metastasis PCNA_N PF00705.13 GAO89721.1 - 3e-54 181.9 3.1 6.1e-54 180.9 2.2 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 GAO89721.1 - 5.2e-52 175.1 0.0 1e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Vezatin PF12632.2 GAO89721.1 - 3.8e-47 160.4 0.1 3.4e-24 85.3 0.0 2.6 1 1 1 2 2 2 2 Mysoin-binding motif of peroxisomes Rad9 PF04139.8 GAO89721.1 - 4e-08 32.7 0.2 5.9e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 GAO89721.1 - 0.0031 16.5 0.4 0.026 13.4 0.0 2.1 2 0 0 2 2 2 1 Hus1-like protein PLDc_N PF13396.1 GAO89721.1 - 0.11 12.1 0.2 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Sec61_beta PF03911.11 GAO89722.1 - 5.2e-19 67.7 0.6 7.2e-19 67.3 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family Hid1 PF12722.2 GAO89723.1 - 0.0052 14.5 0.7 0.0072 14.0 0.5 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SCIMP PF15050.1 GAO89723.1 - 0.012 15.4 0.7 1 9.2 0.0 3.2 3 0 0 3 3 3 0 SCIMP protein Tmemb_9 PF05434.6 GAO89723.1 - 1.5 8.5 4.0 2.5 7.8 0.0 2.5 1 1 1 2 2 2 0 TMEM9 SSF PF00474.12 GAO89724.1 - 4.6e-14 51.8 29.2 1.1e-11 44.0 19.9 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family Dynein_light PF01221.13 GAO89725.1 - 0.0071 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 LuxE PF04443.7 GAO89725.1 - 0.033 12.8 0.1 0.042 12.5 0.1 1.0 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE RRM_1 PF00076.17 GAO89726.1 - 4.4e-78 256.8 1.9 2.6e-19 68.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO89726.1 - 2.1e-67 223.0 0.2 2e-13 50.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO89726.1 - 4.1e-36 122.6 0.1 2.1e-08 33.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO89726.1 - 1.3e-08 34.4 0.0 0.075 12.8 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAO89726.1 - 1.6e-07 30.9 0.7 3.2 7.5 0.0 5.9 5 1 0 5 5 5 3 Limkain b1 RRM_3 PF08777.6 GAO89726.1 - 0.00079 19.2 6.2 2.7 7.8 0.0 5.2 4 1 1 5 5 5 2 RNA binding motif RRM_2 PF04059.7 GAO89726.1 - 0.032 14.2 0.0 5.2 7.1 0.0 3.3 4 0 0 4 4 4 0 RNA recognition motif 2 TEA PF01285.13 GAO89727.1 - 2.8e-158 527.5 0.1 3.8e-158 527.1 0.0 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 GAO89727.1 - 0.07 13.1 0.2 0.21 11.6 0.2 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Aldo_ket_red PF00248.16 GAO89728.1 - 1.5e-49 168.3 0.0 2e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 GAO89729.1 - 6e-46 153.3 34.4 3.8e-11 42.3 2.7 7.1 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO89729.1 - 4.5e-26 90.3 66.9 2.2e-08 33.7 4.2 5.5 1 1 7 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 GAO89729.1 - 2.2e-17 60.3 33.0 0.1 12.6 0.2 11.9 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 GAO89729.1 - 4.2e-16 57.1 25.9 0.018 15.0 0.1 10.8 6 3 5 11 11 11 5 Leucine Rich repeat LRR_7 PF13504.1 GAO89729.1 - 1.7e-12 45.3 20.2 0.21 11.9 0.1 10.5 9 1 1 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 GAO89729.1 - 3.2e-12 46.3 11.9 9.3e-08 31.8 1.9 3.5 1 1 3 4 4 4 4 Leucine-rich repeat DUF325 PF03804.8 GAO89729.1 - 0.27 10.9 1.2 14 5.4 0.0 3.5 2 1 1 4 4 4 0 Viral domain of unknown function Recep_L_domain PF01030.19 GAO89729.1 - 5.3 7.0 14.2 0.93 9.4 3.2 3.8 1 1 3 4 4 4 0 Receptor L domain NIF PF03031.13 GAO89730.1 - 5.9e-34 117.0 0.2 1.2e-16 60.7 0.0 2.4 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 GAO89731.1 - 1.1e-92 310.1 0.1 2e-92 309.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAO89731.1 - 3.5e-14 53.2 0.0 6.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ALIX_LYPXL_bnd PF13949.1 GAO89731.1 - 0.017 14.1 0.3 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_29 PF13555.1 GAO89731.1 - 0.026 14.0 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAO89731.1 - 0.036 14.0 0.1 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 GAO89731.1 - 0.047 14.5 0.1 0.59 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAO89731.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HemX PF04375.9 GAO89731.1 - 0.073 11.6 0.1 0.16 10.4 0.0 1.5 2 0 0 2 2 2 0 HemX Mg_chelatase PF01078.16 GAO89731.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 GAO89731.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 GAO89731.1 - 0.61 10.3 6.6 14 5.9 4.6 2.2 1 1 0 1 1 1 0 AAA domain Clr2 PF10383.4 GAO89732.1 - 4.4e-42 143.3 0.0 7.5e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 2OG-FeII_Oxy PF03171.15 GAO89733.1 - 0.0021 18.3 0.0 0.0083 16.4 0.0 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.18 GAO89734.1 - 2.8e-13 49.5 0.0 7.5e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAO89734.1 - 3.6e-10 40.4 0.0 6.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Glyco_hydro_12 PF01670.11 GAO89735.1 - 4.8e-36 123.8 0.4 4.8e-36 123.8 0.3 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 GAO89735.1 - 0.038 14.1 5.4 0.89 9.7 0.4 2.5 1 1 1 2 2 2 0 Phage holin Rhamnogal_lyase PF06045.6 GAO89735.1 - 0.14 11.4 0.3 0.2 10.9 0.2 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family ERG2_Sigma1R PF04622.7 GAO89736.1 - 3e-97 324.1 0.2 3.4e-97 323.9 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ATP_bind_3 PF01171.15 GAO89737.1 - 8e-20 71.0 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 GAO89737.1 - 0.0032 17.7 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 GAO89737.1 - 0.0061 15.1 0.0 0.0096 14.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 GAO89737.1 - 0.0089 15.4 1.0 0.0089 15.4 0.7 2.4 3 0 0 3 3 3 1 RecR protein zf-UBR PF02207.15 GAO89737.1 - 0.13 12.0 5.8 1.6 8.4 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF3970 PF13113.1 GAO89737.1 - 0.23 11.1 2.2 4 7.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Complex1_LYR_2 PF13233.1 GAO89738.1 - 7.2e-20 71.4 0.4 8.3e-20 71.2 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAO89738.1 - 0.0022 17.7 0.2 0.0038 16.9 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAO89738.1 - 0.0045 17.1 2.7 0.0061 16.7 1.9 1.4 1 1 0 1 1 1 1 Complex1_LYR-like ERM PF00769.14 GAO89738.1 - 0.07 12.6 0.1 0.079 12.4 0.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RasGEF PF00617.14 GAO89739.1 - 2.9e-45 154.3 0.5 5.4e-45 153.4 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAO89739.1 - 3e-14 53.0 0.2 6.6e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 GAO89739.1 - 2e-10 41.1 0.1 5.8e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 GAO89739.1 - 0.0015 17.9 0.0 0.0068 15.8 0.0 2.0 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 GAO89739.1 - 0.045 13.7 0.1 0.55 10.2 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAO89739.1 - 0.049 13.4 0.1 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Dynamin family Nfu_N PF08712.6 GAO89741.1 - 2.1e-29 100.9 0.0 8.3e-29 99.0 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 GAO89741.1 - 4e-23 80.9 0.1 7e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Ribosomal_L15e PF00827.12 GAO89742.1 - 2.3e-89 297.9 12.2 2.3e-89 297.9 8.5 1.7 2 0 0 2 2 2 1 Ribosomal L15 PSP1 PF04468.7 GAO89742.1 - 1.7e-30 104.8 1.3 3.9e-30 103.6 0.9 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region HECT PF00632.20 GAO89743.1 - 4.8e-74 249.3 0.0 7.4e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 GAO89743.1 - 0.081 12.6 0.6 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADH_N PF08240.7 GAO89744.1 - 1.9e-35 120.9 3.1 4.5e-35 119.7 2.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO89744.1 - 1.6e-16 60.0 0.0 2.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 GAO89744.1 - 0.00095 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Methyltransf_18 PF12847.2 GAO89744.1 - 0.0037 17.8 0.0 0.0088 16.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_3 PF01494.14 GAO89744.1 - 0.058 12.4 0.5 0.094 11.7 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 GAO89744.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 GAO89744.1 - 0.22 11.2 1.8 6.8 6.5 0.4 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) zf-RING_2 PF13639.1 GAO89745.1 - 3.1e-13 49.3 4.8 3.1e-13 49.3 3.3 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAO89745.1 - 4.2e-08 33.0 8.4 5.1e-07 29.6 3.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO89745.1 - 1.2e-05 24.9 2.9 1.2e-05 24.9 2.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAO89745.1 - 2e-05 24.1 7.6 2.3e-05 23.9 2.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO89745.1 - 0.00021 20.8 7.4 0.00046 19.8 3.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO89745.1 - 0.00031 20.7 3.4 0.00086 19.3 2.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 GAO89745.1 - 0.0048 16.5 1.7 0.0048 16.5 1.2 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 GAO89745.1 - 0.023 14.4 0.6 0.43 10.3 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rhabdo_glycop PF00974.13 GAO89745.1 - 0.033 12.4 0.0 0.051 11.8 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein zf-Apc11 PF12861.2 GAO89745.1 - 0.036 13.9 1.3 0.076 12.8 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SIT PF15330.1 GAO89745.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT zf-HC5HC2H_2 PF13832.1 GAO89745.1 - 0.19 11.7 1.6 0.43 10.5 1.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_4 PF15227.1 GAO89745.1 - 2.2 8.2 11.8 0.22 11.4 3.9 2.5 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING Ada3 PF10198.4 GAO89746.1 - 4.4e-46 155.8 0.3 1e-45 154.6 0.2 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF572 PF04502.8 GAO89746.1 - 8.5 5.4 16.9 0.11 11.6 6.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) NPR2 PF06218.6 GAO89747.1 - 4.4e-131 437.5 0.0 9.1e-131 436.4 0.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 DUF1656 PF07869.7 GAO89748.1 - 0.25 11.1 0.6 0.47 10.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Lactamase_B_2 PF12706.2 GAO89749.1 - 2.9e-11 43.2 0.0 6.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAO89749.1 - 5.4e-07 29.4 0.0 1.4e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 GAO89749.1 - 1.5e-06 28.1 0.0 5.3e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 GAO89749.1 - 0.018 14.8 0.0 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Amidohydro_1 PF01979.15 GAO89750.1 - 7.3e-59 200.0 2.8 1.2e-58 199.3 2.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 GAO89750.1 - 3.5e-56 188.5 0.4 6.8e-56 187.6 0.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 GAO89750.1 - 1.8e-41 140.0 0.1 8.6e-41 137.8 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 GAO89750.1 - 1e-38 131.2 0.0 2.4e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 GAO89750.1 - 4e-07 29.7 2.7 1.2e-06 28.2 1.9 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAO89750.1 - 6.9e-05 22.2 0.1 0.00079 18.7 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family HMG_box PF00505.14 GAO89751.1 - 1.3e-10 41.3 1.6 1.3e-10 41.3 1.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAO89751.1 - 1.2e-07 32.0 0.5 6.4e-07 29.6 0.4 2.4 1 1 0 1 1 1 1 HMG-box domain POTRA_2 PF08479.6 GAO89751.1 - 0.17 11.5 0.1 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 POTRA domain, ShlB-type DUF908 PF06012.7 GAO89751.1 - 0.54 9.5 3.5 0.68 9.1 2.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) NAD_binding_1 PF00175.16 GAO89752.1 - 5.8e-33 113.7 0.0 9.2e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAO89752.1 - 1.3e-21 76.5 0.0 2.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAO89752.1 - 1.3e-08 34.8 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAO89752.1 - 0.0021 18.0 0.0 0.0068 16.3 0.0 1.8 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain Ribosomal_L18ae PF01775.12 GAO89753.1 - 4.8e-60 200.8 0.3 6e-60 200.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 GAO89754.1 - 3.4e-10 40.1 0.0 6.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 GAO89754.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) CLTH PF10607.4 GAO89755.1 - 2.5e-29 101.8 0.0 8.4e-29 100.1 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain BTB PF00651.26 GAO89755.1 - 0.0022 17.9 1.6 0.04 13.8 0.0 3.0 4 0 0 4 4 4 1 BTB/POZ domain SNAP PF14938.1 GAO89755.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PG_binding_1 PF01471.13 GAO89756.1 - 0.00012 22.0 0.1 0.18 11.7 0.0 3.3 2 1 0 2 2 2 2 Putative peptidoglycan binding domain NPV_P10 PF05531.7 GAO89756.1 - 0.18 12.0 0.2 3.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 GAO89756.1 - 4.3 5.0 5.3 3.2 5.5 2.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family zf-Tim10_DDP PF02953.10 GAO89757.1 - 9.6e-26 88.8 1.4 1.1e-25 88.6 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RIH_assoc PF08454.6 GAO89757.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated tRNA-synt_2 PF00152.15 GAO89758.1 - 9.9e-80 267.8 0.0 1.1e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAO89758.1 - 9.6e-07 28.2 0.1 0.0006 19.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 GAO89758.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 GAO89758.1 - 0.001 18.6 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) SKN1 PF03935.10 GAO89759.1 - 0.06 11.4 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Acetyltransf_8 PF13523.1 GAO89761.1 - 1.4e-51 174.3 0.0 1.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAO89761.1 - 4.7e-06 26.8 0.0 9.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAO89761.1 - 0.11 12.4 0.0 0.56 10.1 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.10 GAO89762.1 - 2.9e-12 45.9 0.0 1.7e-10 40.1 0.0 3.2 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAO89762.1 - 1.5e-07 31.5 0.0 3.8e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3530 PF12048.3 GAO89762.1 - 0.0045 16.0 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Ribosomal_S16 PF00886.14 GAO89762.1 - 0.0093 15.6 0.2 0.068 12.9 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S16 NAD_binding_7 PF13241.1 GAO89762.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2569 PF10754.4 GAO89764.1 - 0.046 13.9 2.3 0.08 13.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) LRR19-TM PF15176.1 GAO89764.1 - 0.96 9.1 3.0 8.9 6.0 0.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1992 PF09350.5 GAO89765.1 - 4.5e-25 87.2 0.3 9.2e-25 86.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) CHCH PF06747.8 GAO89766.1 - 0.00041 20.1 0.7 0.0006 19.6 0.5 1.2 1 0 0 1 1 1 1 CHCH domain p450 PF00067.17 GAO89767.1 - 9.1e-48 162.9 0.0 1.1e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 GAO89768.1 - 0.00038 20.1 0.2 0.00038 20.1 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAO89768.1 - 0.0032 17.0 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain SRP40_C PF05022.7 GAO89769.1 - 2.9e-23 82.1 0.5 9.9e-23 80.4 0.3 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3_C PF09763.4 GAO89770.1 - 5.1e-218 725.6 0.0 6.7e-218 725.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 GAO89770.1 - 2.9e-30 103.9 0.0 6e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 GAO89770.1 - 0.011 15.8 0.3 0.038 14.1 0.2 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit adh_short PF00106.20 GAO89771.1 - 2.9e-07 30.5 0.0 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO89771.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DOCK-C2 PF14429.1 GAO89772.1 - 4.9e-35 120.8 0.0 1.2e-34 119.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 GAO89772.1 - 3.7e-18 65.4 0.1 7.6e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 GAO89772.1 - 3.3e-05 23.1 0.0 7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO89772.1 - 0.00022 20.7 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Metallophos_2 PF12850.2 GAO89773.1 - 3.8e-10 39.8 0.0 1e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAO89773.1 - 1.1e-09 38.0 0.4 0.00011 21.6 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase SSFA2_C PF14723.1 GAO89773.1 - 0.04 13.6 0.1 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Ribosomal_S8e PF01201.17 GAO89774.1 - 9.8e-47 158.4 3.0 1.1e-46 158.2 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.4 GAO89775.1 - 3.4e-17 62.4 0.1 5.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) TFIIF_alpha PF05793.7 GAO89776.1 - 0.36 9.1 30.4 0.6 8.4 21.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TSA PF03249.8 GAO89776.1 - 1.7 7.0 14.9 2.3 6.6 10.3 1.1 1 0 0 1 1 1 0 Type specific antigen Hid1 PF12722.2 GAO89776.1 - 7 4.1 13.9 7.8 4.0 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 GAO89777.1 - 5.6 5.4 11.7 6.6 5.2 8.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPX PF03105.14 GAO89778.1 - 4.5e-50 170.9 0.0 4.5e-50 170.9 0.0 2.8 3 0 0 3 3 3 1 SPX domain Na_sulph_symp PF00939.14 GAO89778.1 - 1.1e-31 110.2 40.6 1.6e-31 109.7 28.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.16 GAO89778.1 - 1.1e-28 99.6 0.0 2.5e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CitMHS PF03600.11 GAO89778.1 - 2.4e-12 46.1 50.5 6.7e-12 44.6 15.3 3.0 2 1 1 3 3 3 3 Citrate transporter Na_Ca_ex PF01699.19 GAO89779.1 - 2.2e-45 153.7 36.2 3.9e-23 81.5 9.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF912 PF06024.7 GAO89779.1 - 0.55 10.3 2.7 1.1 9.3 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_hydro_81 PF03639.8 GAO89780.1 - 1.5e-205 684.2 2.1 2.6e-205 683.4 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 GAO89781.1 - 4e-238 792.3 74.3 4e-238 792.3 51.5 2.1 1 1 1 2 2 2 1 Utp14 protein Phosphodiest PF01663.17 GAO89781.1 - 0.0055 16.0 0.0 0.0055 16.0 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase_C PF00433.19 GAO89781.1 - 0.018 15.5 0.1 0.07 13.6 0.1 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain MRP-L27 PF09809.4 GAO89782.1 - 7.7e-15 54.4 0.5 1e-14 54.1 0.4 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 GAO89783.1 - 1.9e-87 293.3 0.0 3e-87 292.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 GAO89783.1 - 0.0036 16.7 0.6 0.014 14.9 0.4 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.17 GAO89784.1 - 2.6e-82 270.4 6.8 8.9e-23 79.7 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO89784.1 - 1.7e-57 191.3 1.2 1.4e-17 63.3 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO89784.1 - 5.1e-44 147.9 0.8 2.6e-10 39.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAO89784.1 - 4.3e-32 109.6 0.6 4.3e-32 109.6 0.4 2.9 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 GAO89784.1 - 6.8e-06 25.7 0.9 4.1 7.2 0.0 4.7 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 GAO89784.1 - 3.5e-05 23.9 0.1 0.66 10.2 0.0 3.6 4 0 0 4 4 4 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 GAO89784.1 - 4.7e-05 23.0 4.1 0.32 10.7 0.2 3.7 3 0 0 3 3 3 3 Limkain b1 OB_RNB PF08206.6 GAO89784.1 - 0.039 13.4 2.7 6.8 6.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fungal_trans PF04082.13 GAO89785.1 - 2.3e-21 75.8 0.1 4.7e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 GAO89786.1 - 1.4e-78 264.3 0.0 1.7e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Iso_dh PF00180.15 GAO89787.1 - 2.3e-88 296.4 0.0 2.8e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DoxX_2 PF13564.1 GAO89787.1 - 0.069 13.1 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 DoxX-like family MOSC PF03473.12 GAO89789.1 - 9.8e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain VCBS PF13517.1 GAO89790.1 - 2.5e-15 56.5 16.5 1.4e-07 31.7 1.4 3.4 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAO89790.1 - 3.2e-10 39.3 5.8 0.0083 15.7 0.0 4.4 4 0 0 4 4 4 3 FG-GAP repeat TcdB_toxin_midN PF12256.3 GAO89790.1 - 4.9e-07 29.3 3.5 0.012 15.0 0.1 3.8 1 1 3 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.27 GAO89790.1 - 8e-05 21.6 8.3 1.7 8.1 0.1 4.4 4 0 0 4 4 4 2 EF hand DUF756 PF05506.7 GAO89790.1 - 0.00023 21.5 7.0 6.1 7.4 0.0 4.6 2 1 3 5 5 5 1 Domain of unknown function (DUF756) CCAP PF11105.3 GAO89790.1 - 0.0021 17.7 0.0 14 5.4 0.0 3.8 3 1 1 4 4 4 0 Arthropod cardioacceleratory peptide 2a EF-hand_6 PF13405.1 GAO89790.1 - 0.0023 17.6 5.2 4.3 7.4 0.1 4.5 4 0 0 4 4 4 1 EF-hand domain Cleaved_Adhesin PF07675.6 GAO89790.1 - 0.0025 17.4 2.6 0.21 11.1 0.0 3.5 1 1 3 4 4 4 1 Cleaved Adhesin Domain CBM_6 PF03422.10 GAO89790.1 - 0.005 16.9 10.4 8.4 6.5 0.2 4.9 1 1 4 5 5 5 1 Carbohydrate binding module (family 6) RNB PF00773.14 GAO89790.1 - 0.013 14.7 0.4 2.1 7.5 0.0 3.4 4 0 0 4 4 4 0 RNB domain EF-hand_5 PF13202.1 GAO89790.1 - 0.023 14.0 14.7 0.74 9.2 0.1 3.9 4 0 0 4 4 4 0 EF hand DUF1905 PF08922.6 GAO89790.1 - 0.056 13.0 1.3 16 5.1 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1905) Crystall_2 PF09076.5 GAO89790.1 - 0.35 10.6 7.1 2 8.2 0.1 3.8 5 0 0 5 5 4 0 Beta/Gamma crystallin EF-hand_7 PF13499.1 GAO89790.1 - 0.38 10.9 5.2 18 5.5 0.7 3.8 3 1 0 3 3 3 0 EF-hand domain pair FaeA PF04703.7 GAO89790.1 - 0.71 10.0 4.2 43 4.3 0.0 3.8 4 0 0 4 4 4 0 FaeA-like protein SKN1 PF03935.10 GAO89790.1 - 1.1 7.3 7.1 0.48 8.5 0.1 3.0 1 1 3 4 4 4 0 Beta-glucan synthesis-associated protein (SKN1) EF-hand_4 PF12763.2 GAO89790.1 - 9.6 6.0 10.4 26 4.6 0.1 4.0 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CoA_trans PF01144.18 GAO89791.1 - 7.2e-97 322.7 1.2 5.8e-57 192.3 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Fungal_trans PF04082.13 GAO89792.1 - 2.1e-11 43.2 0.1 9.3e-11 41.0 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO89792.1 - 2.4e-07 30.7 15.4 0.00096 19.3 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAO89792.1 - 5.1e-06 26.5 9.0 5.1e-06 26.5 6.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO89792.1 - 1.4e-05 25.0 12.2 0.015 15.6 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAO89792.1 - 0.00062 19.8 9.8 0.12 12.5 1.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO89792.1 - 0.0012 18.9 10.7 0.066 13.3 3.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAO89792.1 - 0.053 13.4 6.8 0.079 12.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 GAO89792.1 - 4.2 7.1 8.6 4.4 7.0 1.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 GAO89792.1 - 6.3 6.6 10.1 0.83 9.4 2.7 2.3 1 1 1 2 2 2 0 BED zinc finger DAO PF01266.19 GAO89794.1 - 1.1e-50 172.5 0.6 1.8e-50 171.8 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO89794.1 - 2.1e-05 24.4 0.1 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO89794.1 - 0.00018 21.6 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO89794.1 - 0.0061 15.6 0.9 0.027 13.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAO89794.1 - 0.0089 15.1 0.8 0.032 13.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 GAO89794.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAO89794.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO89794.1 - 0.034 13.2 0.4 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 GAO89794.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 GAO89794.1 - 0.081 12.3 0.3 0.22 10.9 0.2 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAO89794.1 - 0.11 12.8 0.0 0.3 11.4 0.1 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAO89794.1 - 0.23 11.2 1.2 0.96 9.2 0.1 2.3 2 0 0 2 2 2 0 ThiF family FAD_binding_2 PF00890.19 GAO89794.1 - 0.54 9.0 4.2 1.3 7.7 2.9 1.7 1 1 0 1 1 1 0 FAD binding domain Vps52 PF04129.7 GAO89795.1 - 9.7e-119 397.1 0.0 1.3e-118 396.7 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 GAO89795.1 - 3.1e-05 22.3 0.1 4.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec8_exocyst PF04048.9 GAO89795.1 - 0.00085 18.9 0.5 0.0034 17.0 0.4 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain THOC7 PF05615.8 GAO89795.1 - 0.0038 17.4 1.7 0.015 15.5 0.3 2.3 2 0 0 2 2 2 1 Tho complex subunit 7 DUF3418 PF11898.3 GAO89795.1 - 0.026 12.9 1.2 0.048 12.0 0.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3418) Med4 PF10018.4 GAO89795.1 - 0.038 13.3 0.9 0.081 12.3 0.6 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Laminin_II PF06009.7 GAO89795.1 - 0.6 9.8 4.8 6.8 6.4 0.2 2.7 3 0 0 3 3 3 0 Laminin Domain II eIF-5a PF01287.15 GAO89796.1 - 4.9e-29 100.0 1.1 7.7e-29 99.4 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 GAO89796.1 - 1.7e-05 24.3 1.5 3.7e-05 23.2 1.0 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 GAO89796.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Nitro_FeMo-Co PF02579.12 GAO89796.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor RRN7 PF11781.3 GAO89797.1 - 1.2e-09 37.4 5.1 2.2e-09 36.6 3.5 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 ubiquitin PF00240.18 GAO89798.1 - 1.3e-34 117.3 0.7 1.8e-34 116.9 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAO89798.1 - 8.7e-31 105.2 11.2 1.4e-30 104.6 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAO89798.1 - 9.6e-19 66.8 0.5 9.6e-19 66.8 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAO89798.1 - 1.2e-05 25.4 0.1 4.5e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAO89798.1 - 0.0012 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 GAO89798.1 - 0.0078 16.3 0.0 0.008 16.3 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAO89798.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Fer2_3 PF13085.1 GAO89798.1 - 0.13 12.1 1.6 0.52 10.1 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain RabGAP-TBC PF00566.13 GAO89799.1 - 6.5e-24 84.5 0.1 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.12 GAO89799.1 - 1.2e-13 50.9 15.1 2.9e-13 49.6 10.4 1.7 1 0 0 1 1 1 1 Yip1 domain ATP-synt_J PF04911.7 GAO89799.1 - 0.63 9.5 2.0 6.9 6.2 0.1 2.9 3 0 0 3 3 3 0 ATP synthase j chain MMS1_N PF10433.4 GAO89800.1 - 4.2e-154 513.4 0.0 3.7e-153 510.3 0.0 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAO89800.1 - 9.1e-12 44.6 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region IL12p40_C PF10420.4 GAO89800.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus GTP_EFTU PF00009.22 GAO89801.1 - 5.8e-32 110.6 0.0 3.5e-31 108.1 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAO89801.1 - 3.6e-18 65.4 0.1 9.4e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAO89801.1 - 1.4e-11 44.3 0.9 1.7e-09 37.6 0.0 3.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO89801.1 - 3.3e-06 27.0 0.0 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAO89801.1 - 0.00036 20.1 0.1 0.0014 18.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 GAO89801.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 GAO89801.1 - 0.0027 18.1 0.0 0.019 15.4 0.0 2.5 1 0 0 1 1 1 1 Miro-like protein Rhodanese PF00581.15 GAO89802.1 - 2.2e-12 47.3 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 GAO89803.1 - 3.5e-55 187.3 0.0 5.1e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 GAO89804.1 - 0.00021 21.1 3.5 0.052 13.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO89804.1 - 0.0015 18.1 0.1 0.1 12.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89804.1 - 0.0062 16.3 2.3 1 9.4 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAO89804.1 - 0.068 12.8 5.3 2.8 7.6 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAO89804.1 - 0.093 12.3 2.3 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 TPR repeat PPR_2 PF13041.1 GAO89805.1 - 3e-23 81.5 0.6 5.5e-11 42.2 0.0 7.6 8 0 0 8 8 8 2 PPR repeat family PPR_3 PF13812.1 GAO89805.1 - 1.5e-22 77.9 5.1 0.00011 22.1 0.0 11.4 13 0 0 13 13 13 6 Pentatricopeptide repeat domain PPR PF01535.15 GAO89805.1 - 1.8e-15 55.7 6.4 0.00011 21.9 0.0 9.9 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.2 GAO89805.1 - 2.2e-08 33.4 0.1 0.045 13.2 0.0 5.2 4 0 0 4 4 4 3 PPR repeat MCM PF00493.18 GAO89806.1 - 1.2e-129 431.8 0.1 1.7e-129 431.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAO89806.1 - 8.3e-16 58.5 0.0 2.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAO89806.1 - 3.5e-06 26.3 0.0 4.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAO89806.1 - 0.0069 16.0 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Lin-8 PF03353.10 GAO89806.1 - 5 6.3 9.2 8.9 5.4 6.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spo7 PF03907.8 GAO89807.1 - 4.1e-67 225.8 0.0 6.1e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 GAO89808.1 - 9.2e-27 94.3 2.2 2e-26 93.2 0.3 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO89808.1 - 4.5e-17 62.3 0.0 5.2e-15 55.6 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO89808.1 - 3.1e-12 46.4 0.0 2.2e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 GAO89808.1 - 0.00024 20.2 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 GAO89808.1 - 0.0021 17.5 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 GAO89808.1 - 0.014 14.8 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 GAO89808.1 - 0.027 13.3 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 GAO89808.1 - 0.048 13.2 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 GAO89808.1 - 0.05 13.1 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAO89808.1 - 0.056 13.3 0.4 0.26 11.1 0.0 2.3 3 0 0 3 3 3 0 Putative lysophospholipase PGAP1 PF07819.8 GAO89808.1 - 0.12 11.8 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein TatD_DNase PF01026.16 GAO89810.1 - 1.7e-25 89.7 0.0 4.1e-25 88.4 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 GAO89810.1 - 1.6e-24 86.2 0.3 1.8e-23 82.7 0.0 2.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89810.1 - 1.2e-09 37.9 11.3 1.9e-09 37.2 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRDE-2 PF08424.5 GAO89810.1 - 0.031 13.1 0.0 0.092 11.6 0.0 1.8 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference zinc_ribbon_6 PF14599.1 GAO89810.1 - 0.24 11.2 2.6 0.51 10.1 1.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon CBFD_NFYB_HMF PF00808.18 GAO89811.1 - 2.7e-29 101.0 0.9 4e-29 100.4 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAO89811.1 - 1.1e-06 28.6 0.1 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAO89811.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 GAO89811.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 GAO89811.1 - 0.046 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 GAO89812.1 - 1.2e-23 82.8 3.8 1.5e-23 82.5 2.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit STAT_alpha PF01017.15 GAO89812.1 - 0.0028 17.4 2.7 0.0035 17.0 1.9 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain GAS PF13851.1 GAO89812.1 - 0.0065 15.6 2.4 0.0098 15.1 1.6 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Prefoldin PF02996.12 GAO89812.1 - 0.016 14.8 3.3 0.22 11.1 0.0 2.1 1 1 0 2 2 2 0 Prefoldin subunit p25-alpha PF05517.7 GAO89812.1 - 0.024 14.8 0.2 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 p25-alpha Tho2 PF11262.3 GAO89812.1 - 0.033 13.2 0.8 0.082 11.9 0.5 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CENP-F_leu_zip PF10473.4 GAO89812.1 - 0.086 12.7 3.7 0.41 10.5 0.6 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 GAO89812.1 - 0.11 12.2 0.9 0.28 10.9 0.1 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DASH_Dad3 PF08656.5 GAO89812.1 - 0.11 12.1 3.6 0.16 11.7 0.4 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4200 PF13863.1 GAO89812.1 - 0.15 12.0 5.1 0.25 11.2 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 GAO89812.1 - 0.15 11.7 4.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Flu_M1_C PF08289.6 GAO89812.1 - 0.18 11.8 0.5 5.2 7.1 0.1 2.2 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF1978 PF09321.5 GAO89812.1 - 0.19 11.1 3.5 0.94 8.8 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) FliE PF02049.13 GAO89812.1 - 0.2 11.7 3.0 0.63 10.1 0.8 2.0 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF916 PF06030.7 GAO89812.1 - 0.24 11.2 1.7 8.3 6.2 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Borrelia_lipo_1 PF05714.6 GAO89812.1 - 0.32 10.0 5.7 0.3 10.1 2.2 1.9 1 1 1 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein IncA PF04156.9 GAO89812.1 - 0.94 9.0 8.1 3.1 7.3 5.6 1.7 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 GAO89812.1 - 2.2 8.3 4.1 26 4.8 0.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 GAO89812.1 - 5.6 7.3 7.2 7.4 6.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) HA2 PF04408.18 GAO89813.1 - 3.8e-24 84.6 0.0 1.1e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAO89813.1 - 1.3e-22 79.7 0.0 1.5e-21 76.3 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAO89813.1 - 2e-14 53.2 0.1 6.6e-14 51.5 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO89813.1 - 7.2e-07 28.8 0.1 4.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAO89813.1 - 5.4e-05 23.3 0.1 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAO89813.1 - 0.00054 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 GAO89813.1 - 0.0016 18.2 0.0 0.77 9.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAO89813.1 - 0.0073 15.9 0.6 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAO89813.1 - 0.0078 16.1 0.1 0.064 13.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 GAO89813.1 - 0.011 15.1 0.2 0.031 13.7 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 GAO89813.1 - 0.013 14.6 0.0 0.082 12.0 0.0 2.1 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 GAO89813.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 GAO89813.1 - 0.014 15.0 1.4 0.016 14.8 0.0 1.8 2 0 0 2 2 1 0 Archaeal ATPase Flavi_DEAD PF07652.9 GAO89813.1 - 0.021 14.6 0.1 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.17 GAO89813.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 GAO89813.1 - 0.038 13.9 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 GAO89813.1 - 0.047 13.3 0.9 0.44 10.1 0.6 2.4 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAO89813.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 GAO89813.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAO89813.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAD PF02109.11 GAO89814.1 - 8.5e-33 112.7 0.7 9.9e-33 112.5 0.5 1.1 1 0 0 1 1 1 1 DAD family TrbL PF04610.9 GAO89814.1 - 0.0046 16.6 1.0 0.0055 16.4 0.7 1.0 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF4191 PF13829.1 GAO89814.1 - 0.11 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) LicD PF04991.8 GAO89815.1 - 1.4e-32 113.4 3.7 9.1e-32 110.8 2.5 2.2 1 1 0 1 1 1 1 LicD family Fungal_trans PF04082.13 GAO89815.1 - 2.8e-22 78.8 0.0 5.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89815.1 - 1.7e-10 40.5 10.8 3.7e-10 39.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO89816.1 - 2e-07 30.1 0.0 3.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89816.1 - 0.0016 18.2 8.7 0.003 17.4 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF726 PF05277.7 GAO89818.1 - 3.6e-129 430.5 1.5 5e-129 430.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 GAO89818.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 GAO89818.1 - 0.069 12.9 0.2 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family RTC4 PF14474.1 GAO89819.1 - 2.3e-36 124.4 0.0 4.6e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Cas_Csd1 PF09709.5 GAO89819.1 - 0.012 13.9 0.0 0.044 12.0 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) TFR_dimer PF04253.10 GAO89820.1 - 1.7e-17 63.1 0.0 3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAO89820.1 - 3.4e-15 56.2 0.0 7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAO89820.1 - 5e-06 26.1 0.0 1.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 GAO89820.1 - 0.0018 17.5 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Nicastrin PrgI PF12666.2 GAO89820.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 PrgI family protein MFS_1 PF07690.11 GAO89821.1 - 9.3e-28 96.9 24.1 9.3e-28 96.9 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_14 PF03647.8 GAO89822.1 - 6.5e-23 80.9 6.5 7.7e-23 80.7 4.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.13 GAO89822.1 - 0.00027 20.2 1.8 0.00031 20.0 1.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Glug PF07581.7 GAO89822.1 - 8.6 6.8 6.0 2.7 8.3 0.7 2.4 2 1 0 2 2 2 0 The GLUG motif zf-C2H2 PF00096.21 GAO89823.1 - 0.001 19.3 3.0 0.027 14.7 0.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89823.1 - 0.0011 19.1 1.5 0.052 13.8 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAO89823.1 - 0.16 12.1 1.5 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 GAO89823.1 - 0.21 11.7 0.9 3.9 7.6 0.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CMD PF02627.15 GAO89825.1 - 4.5e-08 32.8 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF2413 PF10310.4 GAO89826.1 - 1.7e-158 528.1 0.1 1.9e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 GAO89826.1 - 0.0024 17.8 0.5 0.0076 16.2 0.3 1.8 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain SurE PF01975.12 GAO89827.1 - 4.9e-48 163.0 0.0 7.1e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 GAO89827.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Allantoicase PF03561.10 GAO89827.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Allantoicase repeat Zn_clus PF00172.13 GAO89828.1 - 0.0049 16.7 10.2 0.011 15.6 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUC153 PF08159.7 GAO89828.1 - 0.039 13.5 1.0 0.067 12.8 0.0 2.0 2 0 0 2 2 2 0 NUC153 domain DUF2462 PF09495.5 GAO89829.1 - 3.4e-23 82.1 9.0 3.4e-23 82.1 6.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) GPI-anchored PF10342.4 GAO89830.1 - 2.4e-24 85.6 0.5 2.4e-24 85.6 0.3 2.1 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 GAO89830.1 - 0.019 14.4 0.3 0.042 13.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Aldedh PF00171.17 GAO89831.1 - 6.4e-136 453.3 0.7 7.8e-136 453.0 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO89831.1 - 5.5e-06 25.3 0.0 4.7e-05 22.2 0.0 1.9 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) Protoglobin PF11563.3 GAO89832.1 - 5e-56 188.7 0.1 6.1e-56 188.4 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Cellulase PF00150.13 GAO89833.1 - 9.2e-22 77.5 0.1 1.6e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAO89833.1 - 0.0075 15.4 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 GAO89833.1 - 0.083 13.3 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-binding cellulase-like IBN_N PF03810.14 GAO89834.1 - 6.8e-13 48.3 4.1 4e-12 45.8 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAO89834.1 - 0.0015 18.4 3.5 0.016 15.1 0.1 3.7 3 1 1 4 4 4 1 Exportin 1-like protein Phosphoesterase PF04185.9 GAO89836.1 - 1.6e-35 123.0 5.3 7.9e-35 120.7 3.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family Pex2_Pex12 PF04757.9 GAO89837.1 - 7.1e-44 149.9 2.5 1e-43 149.3 1.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 GAO89837.1 - 0.0019 18.0 4.8 0.0038 17.0 3.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAO89837.1 - 0.23 11.2 2.3 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger ILVD_EDD PF00920.16 GAO89838.1 - 1.3e-204 680.4 1.7 1.5e-204 680.2 1.2 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 GAO89838.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Abhydrolase_6 PF12697.2 GAO89839.1 - 2.7e-23 83.0 0.9 2.5e-22 79.8 1.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO89839.1 - 7.2e-13 48.5 0.0 5.6e-12 45.6 0.0 2.3 2 1 0 2 2 1 1 Alpha/beta hydrolase family DSPc PF00782.15 GAO89839.1 - 3.2e-11 42.9 0.0 8.6e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 GAO89839.1 - 1e-08 35.0 0.0 3.5e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAO89839.1 - 0.0013 18.9 0.1 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 GAO89839.1 - 0.0024 17.4 0.1 0.0091 15.6 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 GAO89839.1 - 0.0033 17.0 0.0 0.024 14.2 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 GAO89839.1 - 0.0057 16.1 0.0 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 GAO89839.1 - 0.0093 15.5 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase PAF-AH_p_II PF03403.8 GAO89839.1 - 0.01 14.1 0.8 0.072 11.3 0.1 2.4 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 GAO89839.1 - 0.013 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.22 GAO89839.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAO89839.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_3 PF07859.8 GAO89839.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.5 GAO89839.1 - 0.031 13.1 0.0 2.2 7.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) DUF676 PF05057.9 GAO89839.1 - 0.041 13.1 0.0 0.38 10.0 0.0 2.3 2 1 0 2 2 2 0 Putative serine esterase (DUF676) Sugar_tr PF00083.19 GAO89840.1 - 1.5e-119 399.5 22.6 2.3e-119 398.9 15.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89840.1 - 1.4e-24 86.4 37.4 3.4e-18 65.4 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.26 GAO89841.1 - 4.8e-20 71.0 0.1 1.4e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain ATP-synt PF00231.14 GAO89842.1 - 1.2e-60 205.3 9.6 1.5e-60 205.0 6.7 1.1 1 0 0 1 1 1 1 ATP synthase DUF1957 PF09210.6 GAO89842.1 - 0.053 13.5 0.1 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Topoisom_I_N PF02919.10 GAO89843.1 - 1.6e-98 328.2 1.1 1.6e-98 328.2 0.8 3.8 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 GAO89843.1 - 3.9e-83 278.1 6.1 3.9e-83 278.1 4.2 2.6 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 GAO89843.1 - 1e-33 114.8 0.6 3.7e-33 112.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Ribosomal_S15 PF00312.17 GAO89843.1 - 6.6 6.5 10.3 0.37 10.5 1.6 3.0 2 1 1 3 3 3 0 Ribosomal protein S15 Epimerase PF01370.16 GAO89844.1 - 1.7e-20 73.4 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO89844.1 - 8.8e-08 31.1 0.0 6.6e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO89844.1 - 4.5e-07 29.9 0.0 2.1e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO89844.1 - 3.6e-05 23.8 0.0 0.00015 21.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAO89844.1 - 7.1e-05 21.8 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 GAO89844.1 - 0.008 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAO89844.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 GAO89844.1 - 0.0099 15.5 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAO89844.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AbiH PF14253.1 GAO89845.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF605 PF04652.11 GAO89846.1 - 3.7e-108 362.3 15.8 4.2e-108 362.1 10.9 1.0 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 GAO89846.1 - 4.2 5.5 16.7 6.7 4.8 11.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C2 PF00648.16 GAO89847.1 - 2.5e-24 85.7 0.0 4.1e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 GAO89847.1 - 1.4e-20 73.3 0.0 2e-17 63.2 0.0 3.8 4 0 0 4 4 4 2 Calpain large subunit, domain III MIT PF04212.13 GAO89847.1 - 2.4e-09 36.9 7.3 4e-09 36.2 5.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 GAO89848.1 - 4.1e-55 183.4 0.8 1.5e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.3 GAO89848.1 - 0.093 12.7 0.9 0.75 9.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3147) SNase PF00565.12 GAO89849.1 - 1.7e-20 73.2 0.0 3.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.17 GAO89850.1 - 1.7e-35 122.1 0.0 1.2e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 GAO89850.1 - 7.9e-13 47.8 0.0 1.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 GAO89850.1 - 1.1e-05 25.6 0.0 2.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO89850.1 - 0.00023 21.9 0.0 0.00074 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAO89850.1 - 0.00089 19.1 0.0 0.0066 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAO89850.1 - 0.095 12.6 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAO89850.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 GAO89850.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 GAO89850.1 - 0.15 11.4 0.0 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase DNA_primase_lrg PF04104.9 GAO89851.1 - 1.8e-82 276.4 0.0 2.7e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ENT PF03735.9 GAO89851.1 - 0.051 13.2 0.1 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 ENT domain Sec23_trunk PF04811.10 GAO89852.1 - 3.9e-81 272.0 0.0 5.6e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAO89852.1 - 6.4e-33 112.2 0.0 1.2e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAO89852.1 - 3.2e-29 101.2 0.0 6.7e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAO89852.1 - 3.8e-16 58.3 4.5 8.4e-16 57.2 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAO89852.1 - 2e-12 46.6 0.0 1.4e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 GAO89853.1 - 6.2e-18 64.0 0.1 9.5e-18 63.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAO89853.1 - 1.2e-09 38.1 0.1 1.8e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.1 GAO89854.1 - 3.9e-99 331.7 0.0 3.7e-49 166.9 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 GAO89854.1 - 1.7e-19 69.2 16.0 1.1e-07 31.3 0.1 4.7 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 GAO89854.1 - 1.2e-17 62.6 10.1 2.9e-05 23.4 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAO89854.1 - 1.1e-14 53.0 16.0 0.0022 17.7 0.0 6.1 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAO89854.1 - 1.5e-12 47.2 15.3 1.8e-06 27.7 1.1 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAO89854.1 - 3.2e-11 42.4 4.5 0.23 11.7 0.1 5.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAO89854.1 - 7e-11 42.5 17.5 0.0014 19.2 0.5 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAO89854.1 - 2.1e-10 40.2 15.1 0.0021 18.5 0.1 5.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAO89854.1 - 1.2e-09 37.2 1.5 0.052 13.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAO89854.1 - 3.4e-07 29.5 7.7 0.15 11.9 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAO89854.1 - 9e-06 25.9 10.5 0.0035 17.6 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAO89854.1 - 0.00012 21.9 22.4 0.049 13.5 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_5 PF12688.2 GAO89854.1 - 0.00046 20.2 1.1 0.043 13.8 0.1 3.3 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_15 PF13429.1 GAO89854.1 - 0.0031 16.6 0.3 0.44 9.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO89854.1 - 0.0071 16.4 3.7 0.09 12.9 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 GAO89854.1 - 0.0096 16.2 4.0 2.7 8.2 0.1 3.1 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 GAO89854.1 - 0.013 15.9 6.3 29 5.4 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAO89854.1 - 0.022 14.6 8.3 0.088 12.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAO89854.1 - 1.4 9.5 9.2 3 8.5 1.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4566 PF15130.1 GAO89855.1 - 0.035 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) ETRAMP PF09716.5 GAO89855.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Aa_trans PF01490.13 GAO89855.1 - 0.2 10.1 0.5 0.28 9.6 0.3 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein DUF4246 PF14033.1 GAO89856.1 - 2.2e-169 564.2 0.0 2.7e-169 564.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Myb_DNA-binding PF00249.26 GAO89857.1 - 7.1e-25 86.8 2.2 2.3e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO89857.1 - 4.6e-20 71.4 3.5 1.1e-14 54.2 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 GAO89857.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 GAO89857.1 - 0.016 15.3 1.5 0.049 13.7 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.1 GAO89857.1 - 0.026 14.1 0.2 0.065 12.9 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.1 GAO89857.1 - 0.028 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3701 PF12482.3 GAO89857.1 - 0.078 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Phage integrase protein MFS_1 PF07690.11 GAO89858.1 - 2.6e-26 92.2 50.8 2.1e-21 76.0 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO89858.1 - 4.6 7.0 15.9 0.028 14.2 1.9 3.7 3 0 0 3 3 3 0 MFS_1 like family PEP_mutase PF13714.1 GAO89860.1 - 6.3e-52 176.1 0.4 8e-52 175.8 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAO89860.1 - 1.2e-13 50.2 0.3 1.6e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 GAO89860.1 - 4.6e-05 22.6 0.0 0.0043 16.2 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase DAHP_synth_1 PF00793.15 GAO89860.1 - 0.088 11.4 0.0 0.55 8.8 0.0 2.2 3 0 0 3 3 3 0 DAHP synthetase I family MFS_1 PF07690.11 GAO89861.1 - 2.2e-31 108.8 20.9 2.2e-31 108.8 14.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO89861.1 - 0.14 11.9 4.3 0.12 12.1 0.4 2.6 2 0 0 2 2 2 0 MFS_1 like family Fumarate_red_C PF02300.12 GAO89861.1 - 2 8.2 6.3 0.63 9.9 1.8 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit C DUF3567 PF12091.3 GAO89862.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Dynamin_N PF00350.18 GAO89863.1 - 8.3e-27 94.0 0.0 1.7e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAO89863.1 - 1.1e-16 60.4 0.0 6.3e-14 51.4 0.0 2.3 1 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 GAO89863.1 - 0.00036 20.4 0.0 0.0062 16.4 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 GAO89863.1 - 0.081 12.8 0.7 0.96 9.3 0.1 2.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain Miro PF08477.8 GAO89863.1 - 0.09 13.2 0.0 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein MFS_1 PF07690.11 GAO89864.1 - 0.0016 17.2 7.1 0.0024 16.6 4.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3632 PF12311.3 GAO89865.1 - 6.7e-32 110.7 6.8 8.8e-32 110.3 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) PAS_4 PF08448.5 GAO89865.1 - 0.085 12.9 0.8 0.24 11.4 0.5 1.8 1 0 0 1 1 1 0 PAS fold DUF1138 PF06592.8 GAO89865.1 - 1.8 8.6 4.0 0.95 9.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) Ribonuclease PF00545.15 GAO89866.1 - 2.8e-11 43.3 0.2 4.1e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 ribonuclease MFS_1 PF07690.11 GAO89867.1 - 2.8e-44 151.2 55.6 1e-42 146.1 36.7 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO89867.1 - 3.6e-10 38.7 17.9 3.6e-10 38.7 12.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 GAO89869.1 - 3.5e-34 118.1 0.0 4.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 GAO89870.1 - 1.9e-86 290.5 0.0 2.2e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 GAO89871.1 - 2.1e-154 513.9 0.0 5.4e-80 268.8 0.0 3.4 3 1 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.15 GAO89871.1 - 1.1e-56 191.9 0.0 1.9e-33 115.6 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAO89871.1 - 1.9e-17 63.2 0.0 1e-07 32.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAO89871.1 - 1.3e-10 41.4 0.0 1.8e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 HxxPF-repeated domain AMP-binding_C PF13193.1 GAO89871.1 - 9.8e-10 39.2 1.7 1.3e-06 29.2 0.6 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GIY-YIG PF01541.19 GAO89873.1 - 0.005 17.1 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain Hce2 PF14856.1 GAO89874.1 - 1.4e-20 73.0 0.1 1.8e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor FAD_binding_3 PF01494.14 GAO89875.1 - 2e-26 92.8 0.0 4.4e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO89875.1 - 4.8e-07 29.0 1.7 6.5e-05 21.9 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO89875.1 - 4.7e-06 26.5 0.3 1.2e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAO89875.1 - 0.0023 16.9 1.3 0.42 9.4 0.2 3.0 2 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAO89875.1 - 0.0048 17.2 0.4 0.027 14.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO89875.1 - 0.016 14.2 0.7 0.022 13.8 0.1 1.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 GAO89875.1 - 0.017 13.9 0.7 0.035 12.9 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 GAO89875.1 - 0.02 14.6 0.2 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAO89875.1 - 0.021 14.6 0.0 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO89875.1 - 0.023 13.5 0.0 0.16 10.7 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.1 GAO89875.1 - 0.053 13.5 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO89875.1 - 0.077 11.4 0.2 0.23 9.8 0.1 1.8 1 1 0 1 1 1 0 HI0933-like protein Glyco_hydro_31 PF01055.21 GAO89876.1 - 3.5e-128 428.1 4.0 4.3e-128 427.9 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO89876.1 - 0.00035 20.3 0.7 0.0053 16.5 0.1 3.0 3 1 0 3 3 3 1 Galactose mutarotase-like DUF2414 PF10309.4 GAO89877.1 - 4e-24 84.0 0.0 6.5e-24 83.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) WD40 PF00400.27 GAO89878.1 - 3.4 7.6 12.5 5.7 6.9 0.1 5.1 5 1 1 6 6 6 0 WD domain, G-beta repeat ATP-synt_DE_N PF02823.11 GAO89879.1 - 1e-20 73.2 0.1 1.4e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2417 PF10329.4 GAO89881.1 - 2.8e-92 308.3 2.4 3.5e-92 308.0 1.7 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 GAO89881.1 - 1.7e-06 28.1 0.1 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2975 PF11188.3 GAO89881.1 - 4.5 6.9 13.6 1.1 8.9 3.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Abhydrolase_6 PF12697.2 GAO89883.1 - 4e-21 75.9 0.1 6.4e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO89883.1 - 2.4e-08 33.8 0.0 6.7e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO89883.1 - 0.00012 21.6 0.1 0.0028 17.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAO89883.1 - 0.084 13.0 0.1 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 GAO89883.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 GAO89884.1 - 1.1e-56 186.7 17.3 3.6e-10 39.3 0.3 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 GAO89884.1 - 1.7e-47 161.0 0.0 2.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 GAO89884.1 - 8.9e-07 28.4 0.0 2.4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 GAO89884.1 - 3e-05 22.3 3.1 0.034 12.2 0.1 3.5 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO89884.1 - 0.0069 15.1 0.1 4.2 6.0 0.0 3.6 2 1 2 4 4 4 1 Nup133 N terminal like eIF2A PF08662.6 GAO89884.1 - 0.012 15.3 0.4 0.072 12.7 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 GAO89884.1 - 0.051 12.6 0.3 14 4.6 0.1 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3550 PF12070.3 GAO89884.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) Med11 PF10280.4 GAO89885.1 - 2.1e-38 130.9 0.0 2.6e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 GAO89885.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 F_actin_cap_B PF01115.12 GAO89886.1 - 4.8e-108 359.9 0.0 5.5e-108 359.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DEAD PF00270.24 GAO89887.1 - 1.3e-19 70.2 0.0 6.2e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO89887.1 - 7.7e-19 67.3 0.1 2.3e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO89887.1 - 8.8e-19 68.0 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAO89887.1 - 0.023 14.8 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain HD PF01966.17 GAO89889.1 - 1.9e-07 31.1 3.9 3.5e-07 30.2 2.7 1.4 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 GAO89889.1 - 0.03 13.6 0.5 0.066 12.4 0.3 1.6 1 1 0 1 1 1 0 HDOD domain WD40 PF00400.27 GAO89890.1 - 0.0014 18.4 1.0 1.4 8.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DPM2 PF07297.7 GAO89891.1 - 8.5e-35 118.8 0.6 9.8e-35 118.6 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 GAO89891.1 - 3.6e-05 23.3 0.5 4.3e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 PIG-P DUF4083 PF13314.1 GAO89891.1 - 0.00088 19.0 1.4 0.00092 18.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) DUF4229 PF14012.1 GAO89891.1 - 0.014 15.3 2.4 0.025 14.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF1469 PF07332.6 GAO89891.1 - 0.37 10.5 4.1 0.49 10.1 2.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3169 PF11368.3 GAO89891.1 - 0.43 9.7 1.8 2.4 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HAMP PF00672.20 GAO89891.1 - 3.3 7.9 4.9 9 6.5 0.4 2.1 2 0 0 2 2 2 0 HAMP domain MIF4G PF02854.14 GAO89892.1 - 4.2e-26 91.6 0.4 8.6e-26 90.6 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 GAO89892.1 - 1.1e-25 89.4 0.0 3.9e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain SET PF00856.23 GAO89893.1 - 8.1e-08 32.7 0.1 0.0016 18.7 0.1 3.2 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 GAO89893.1 - 0.0078 16.0 5.9 0.0078 16.0 4.1 2.1 2 0 0 2 2 2 1 MYND finger WD40 PF00400.27 GAO89894.1 - 3.5e-22 77.3 10.8 6.1e-07 29.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Glucosamine_iso PF01182.15 GAO89895.1 - 2.5e-60 203.6 0.0 3e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_3 PF01494.14 GAO89896.1 - 3.1e-14 52.8 0.0 4.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAO89896.1 - 7.4e-05 21.5 0.3 0.0011 17.6 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.19 GAO89896.1 - 0.0014 17.6 0.8 0.1 11.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO89896.1 - 0.0023 17.9 0.2 0.0066 16.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAO89896.1 - 0.014 15.1 0.1 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAO89896.1 - 0.6 8.8 2.7 0.8 8.4 1.2 1.6 2 0 0 2 2 2 0 FAD binding domain RRM_1 PF00076.17 GAO89897.1 - 1e-18 66.6 0.0 2.8e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO89897.1 - 7.2e-17 61.1 0.0 1.9e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO89897.1 - 0.0003 20.5 0.0 0.00065 19.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 GAO89898.1 - 1.1e-30 106.7 0.1 1.1e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 GAO89899.1 - 3.2e-11 41.6 1.8 2.9e-05 23.0 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAO89899.1 - 5.2e-11 41.4 1.6 7.3e-05 22.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAO89899.1 - 8.7e-09 35.3 3.1 2.2e-07 30.9 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAO89899.1 - 9.6e-08 31.5 0.2 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAO89899.1 - 6.8e-07 28.3 6.8 0.0037 16.5 0.5 2.7 2 1 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 GAO89899.1 - 0.0064 16.3 0.0 6.9 6.6 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain Afi1 PF07792.7 GAO89900.1 - 6.6e-65 217.5 0.2 1e-64 216.9 0.1 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 GAO89900.1 - 2.1e-37 127.3 0.0 3.5e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAO89900.1 - 2.1e-08 33.0 0.1 0.0041 15.6 0.0 3.7 3 1 1 4 4 4 2 Transport protein Avl9 DUF1168 PF06658.7 GAO89900.1 - 0.014 14.9 2.7 0.024 14.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2347 PF09804.4 GAO89900.1 - 0.044 13.0 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Cwf_Cwc_15 PF04889.7 GAO89900.1 - 0.091 12.4 7.2 0.14 11.8 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peripla_BP_6 PF13458.1 GAO89900.1 - 0.098 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Nucleo_P87 PF07267.6 GAO89900.1 - 1.1 7.8 4.9 1.7 7.2 3.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 GAO89900.1 - 2.4 7.4 8.8 3.7 6.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 GAO89900.1 - 2.6 6.3 12.7 3.9 5.7 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 GAO89900.1 - 6.4 4.6 7.9 1.7 6.6 3.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Phos_pyr_kin PF08543.7 GAO89902.1 - 6.8e-12 45.0 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 GAO89902.1 - 2.6e-08 33.3 1.9 1.9e-07 30.5 1.3 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase dUTPase PF00692.14 GAO89903.1 - 1.3e-44 150.7 0.0 2.2e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 GAO89903.1 - 0.051 11.9 0.0 0.073 11.4 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.18 GAO89904.1 - 1.7e-41 142.5 0.0 2.1e-40 138.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAO89904.1 - 5.3e-05 22.4 0.0 0.0001 21.5 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 GAO89904.1 - 0.00041 19.7 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.9 GAO89904.1 - 0.0073 15.3 0.0 0.24 10.3 0.0 2.2 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.6 GAO89904.1 - 0.042 12.4 0.0 0.82 8.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.9 GAO89904.1 - 0.13 11.3 0.0 0.53 9.3 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.21 GAO89905.1 - 1.3e-05 25.1 11.7 0.0055 16.9 1.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAO89905.1 - 1.6e-05 24.8 13.7 0.00068 19.7 2.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO89905.1 - 0.00016 21.7 8.5 0.89 9.9 0.0 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 GAO89905.1 - 0.23 11.6 7.4 0.19 11.8 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 GAO89906.1 - 3.1e-05 23.9 13.6 0.072 13.4 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO89906.1 - 0.00077 19.6 0.0 0.00077 19.6 0.0 3.5 4 0 0 4 4 4 1 Zinc finger, C2H2 type PQ-loop PF04193.9 GAO89907.1 - 2.7e-34 116.5 8.9 2.2e-19 68.7 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_B561 PF03188.11 GAO89908.1 - 0.0014 18.4 10.2 0.093 12.5 4.9 2.3 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 ABA_WDS PF02496.11 GAO89908.1 - 0.14 12.3 2.1 40 4.4 0.0 4.0 4 0 0 4 4 4 0 ABA/WDS induced protein Pex14_N PF04695.8 GAO89908.1 - 1.9 8.5 6.9 2.5 8.1 0.1 3.8 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPL4 PF05021.10 GAO89909.1 - 2.6e-130 434.0 0.0 3.2e-130 433.7 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 GAO89909.1 - 3.4e-73 244.1 0.3 5.3e-73 243.5 0.2 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 GAO89909.1 - 0.0068 16.6 0.0 0.052 13.8 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 GAO89909.1 - 0.41 10.3 3.6 1.4 8.6 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) FMN_red PF03358.10 GAO89910.1 - 2.2e-08 33.7 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 GAO89910.1 - 3.9e-08 33.4 0.2 8.7e-08 32.2 0.2 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 GAO89910.1 - 2.8e-06 26.9 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 GAO89910.1 - 0.0064 16.4 0.0 0.014 15.4 0.0 1.5 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 GAO89910.1 - 0.02 14.2 0.5 0.091 12.1 0.3 2.0 1 1 0 1 1 1 0 Flavodoxin zf-CCCH PF00642.19 GAO89911.1 - 5.6e-20 70.5 28.8 2.4e-07 30.2 0.7 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 GAO89911.1 - 0.04 13.4 6.4 0.65 9.5 0.1 3.3 2 1 0 2 2 2 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.23 GAO89912.1 - 4.7e-64 217.0 0.0 5.3e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 GAO89912.1 - 0.00065 19.4 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Asparaginase PF00710.15 GAO89913.1 - 4.8e-71 239.2 3.0 5.7e-71 238.9 2.1 1.1 1 0 0 1 1 1 1 Asparaginase DUF3712 PF12505.3 GAO89914.1 - 1e-38 132.1 0.7 2.2e-38 131.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAO89914.1 - 0.0016 18.7 1.0 0.054 13.8 0.1 2.4 2 0 0 2 2 2 1 Late embryogenesis abundant protein SecD-TM1 PF13721.1 GAO89914.1 - 0.099 12.9 0.8 0.52 10.5 0.6 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Sel1 PF08238.7 GAO89915.1 - 3.7e-14 52.8 8.1 0.0011 19.4 1.4 4.8 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 GAO89915.1 - 0.33 10.6 2.8 20 4.9 0.9 2.5 2 0 0 2 2 2 0 TPR repeat Far-17a_AIG1 PF04750.9 GAO89916.1 - 1.4e-07 30.8 16.5 2.2e-07 30.2 11.4 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein MadM PF03818.8 GAO89916.1 - 0.053 13.1 1.4 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit DUF1776 PF08643.5 GAO89917.1 - 6.8e-109 363.5 0.0 8.3e-109 363.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 GAO89917.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase WLM PF08325.5 GAO89918.1 - 0.00045 20.1 0.7 0.00081 19.3 0.5 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 GAO89918.1 - 0.00047 19.1 6.5 0.00047 19.1 4.5 3.6 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others Stc1 PF12898.2 GAO89918.1 - 0.0015 18.5 7.0 0.042 13.9 0.5 2.4 1 1 1 2 2 2 2 Stc1 domain DZR PF12773.2 GAO89918.1 - 0.005 16.6 13.9 0.14 11.9 9.7 2.3 1 1 0 1 1 1 1 Double zinc ribbon DUF4379 PF14311.1 GAO89918.1 - 3.2 7.6 10.6 38 4.1 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4379) WD40 PF00400.27 GAO89919.1 - 2e-69 227.1 24.5 6.9e-09 35.2 0.1 11.0 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.7 GAO89919.1 - 4.2e-23 81.3 0.4 7.5e-23 80.5 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 GAO89919.1 - 1.9e-06 26.3 6.9 0.019 13.1 0.0 5.5 4 2 0 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO89919.1 - 0.00013 20.9 3.4 0.2 10.3 0.1 3.9 3 1 1 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 GAO89919.1 - 0.0028 15.9 0.1 0.041 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) P34-Arc PF04045.9 GAO89920.1 - 4.5e-104 346.9 0.3 6.5e-104 346.4 0.2 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PP2C_2 PF13672.1 GAO89921.1 - 0.00014 21.3 0.2 0.00027 20.3 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 GAO89921.1 - 0.00034 20.3 0.0 0.00094 18.9 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 GAO89921.1 - 0.00046 19.6 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C WD40 PF00400.27 GAO89922.1 - 1.4e-28 97.6 5.2 8.6e-08 31.7 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 GAO89922.1 - 4.2e-05 21.8 1.7 0.0027 15.9 0.1 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAO89922.1 - 0.047 12.4 0.0 2.4 6.8 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Cmc1 PF08583.5 GAO89923.1 - 2.8e-18 65.4 4.6 3.4e-18 65.1 3.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3811 PF11656.3 GAO89923.1 - 0.019 15.0 0.9 0.025 14.6 0.6 1.3 1 0 0 1 1 1 0 YjbD family (DUF3811) GCK PF07802.6 GAO89923.1 - 0.23 11.5 1.7 0.37 10.9 0.9 1.5 1 1 0 1 1 1 0 GCK domain Fcf1 PF04900.7 GAO89924.1 - 1.4e-10 41.1 0.3 0.00057 19.9 0.0 3.0 2 1 0 2 2 2 2 Fcf1 Polysacc_syn_2C PF08485.5 GAO89925.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal RRN3 PF05327.6 GAO89926.1 - 1.6e-192 640.5 0.0 2e-192 640.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.8 GAO89927.1 - 2.4e-44 151.4 0.0 3.1e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAO89927.1 - 1.1e-08 34.2 0.2 3.1e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAO89927.1 - 0.00016 21.4 0.0 0.00019 21.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO89927.1 - 0.00058 19.1 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 GAO89927.1 - 0.017 14.5 0.1 0.046 13.1 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 GAO89927.1 - 0.036 13.4 0.0 0.082 12.3 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 GAO89927.1 - 0.042 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) tRNA-synt_2 PF00152.15 GAO89928.1 - 2.5e-77 259.8 0.0 4e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 GAO89928.1 - 4e-18 65.2 0.0 6.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 GAO89928.1 - 0.00075 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAO89928.1 - 0.00084 18.6 0.1 0.91 8.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Tubulin PF00091.20 GAO89930.1 - 2.6e-70 236.6 0.0 3.7e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAO89930.1 - 1.6e-49 167.0 0.0 4.1e-49 165.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAO89930.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 GAO89931.1 - 1.3e-33 114.8 0.0 8.4e-14 51.1 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 GAO89931.1 - 3e-10 40.0 0.0 0.00037 20.5 0.0 4.7 4 1 0 4 4 4 1 EF-hand domain pair UBA PF00627.26 GAO89931.1 - 4.7e-09 35.8 0.0 1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 GAO89931.1 - 5.2e-08 31.6 0.0 0.002 17.3 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 GAO89931.1 - 1.7e-06 27.5 0.2 0.012 15.2 0.0 4.9 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.1 GAO89931.1 - 1.2e-05 24.7 0.9 0.95 9.5 0.0 5.7 6 0 0 6 6 6 1 EF-hand domain GAS PF13851.1 GAO89931.1 - 0.0028 16.8 24.6 0.0062 15.7 7.7 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 GAO89931.1 - 0.091 10.0 22.6 0.13 9.5 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 GAO89931.1 - 0.13 11.9 28.6 0.03 14.0 10.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 GAO89931.1 - 0.17 10.1 11.7 0.29 9.3 8.1 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.3 GAO89931.1 - 0.51 9.5 24.1 0.0062 15.8 8.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.6 GAO89931.1 - 0.55 8.6 19.5 0.93 7.9 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IncA PF04156.9 GAO89931.1 - 1.1 8.8 30.9 9.5 5.7 21.4 2.1 1 1 0 1 1 1 0 IncA protein MAD PF05557.8 GAO89931.1 - 1.8 6.5 25.1 6 4.8 17.4 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.6 GAO89931.1 - 2.1 6.9 25.2 0.83 8.2 7.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 GAO89931.1 - 2.2 5.8 30.3 5.7 4.5 21.0 1.5 1 1 0 1 1 1 0 Myosin tail FUSC PF04632.7 GAO89931.1 - 3.8 5.8 10.1 6.1 5.1 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.7 GAO89931.1 - 7.9 6.2 10.4 1.3 8.8 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sugar_tr PF00083.19 GAO89932.1 - 5.1e-87 292.3 17.4 1.4e-86 290.8 12.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO89932.1 - 2.4e-30 105.4 34.2 1.8e-22 79.5 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAO89932.1 - 0.0002 19.5 8.0 0.042 11.8 0.8 3.2 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 GAO89932.1 - 0.0098 15.6 0.9 1.2 8.9 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family SCIMP PF15050.1 GAO89932.1 - 0.21 11.4 0.1 0.55 10.1 0.0 1.6 2 0 0 2 2 2 0 SCIMP protein PUF PF00806.14 GAO89933.1 - 3.8e-62 202.3 3.6 2.8e-08 32.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 GAO89933.1 - 0.056 12.5 0.1 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DnaB_bind PF10410.4 GAO89933.1 - 0.07 13.1 0.1 6.4 6.8 0.0 3.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase ORC5_C PF14630.1 GAO89934.1 - 1e-97 326.8 0.0 1.3e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 GAO89934.1 - 1.1e-16 61.3 0.8 2.3e-16 60.3 0.5 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAO89934.1 - 0.0026 17.8 0.0 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 GAO89935.1 - 0.0028 17.4 2.4 2.1 8.3 0.3 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat E1-E2_ATPase PF00122.15 GAO89936.1 - 9.2e-63 211.3 8.9 2.2e-62 210.0 6.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAO89936.1 - 1.7e-22 80.8 0.0 3.8e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO89936.1 - 1.3e-12 47.0 0.0 3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAO89936.1 - 4.1e-12 46.6 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO89936.1 - 0.0044 16.6 0.1 0.0084 15.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO89936.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RNA_pol_Rpb2_6 PF00562.23 GAO89937.1 - 8.5e-119 396.7 0.4 1.5e-118 395.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAO89937.1 - 3.3e-55 186.1 0.7 3.3e-55 186.1 0.5 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 GAO89937.1 - 1.5e-29 102.0 0.2 5.1e-29 100.3 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 GAO89937.1 - 2.1e-27 95.8 3.8 4.4e-27 94.7 2.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 GAO89937.1 - 1.7e-21 75.7 1.2 1.3e-20 72.9 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 GAO89937.1 - 1.4e-19 69.5 0.0 3.2e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 GAO89937.1 - 8.1e-14 51.3 0.4 1.8e-13 50.2 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 GAO89937.1 - 0.0054 15.1 0.2 0.011 14.1 0.1 1.5 1 0 0 1 1 1 1 Baculovirus Y142 protein DUF4246 PF14033.1 GAO89938.1 - 1.9e-163 544.6 0.1 2.2e-163 544.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF829 PF05705.9 GAO89939.1 - 1.8e-59 201.3 0.2 2.1e-59 201.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) UFD1 PF03152.9 GAO89940.1 - 4.8e-77 257.0 0.0 6e-77 256.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 GAO89940.1 - 0.011 15.3 0.1 0.21 11.2 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 GAO89941.1 - 2.9e-12 45.9 0.7 6.1e-12 44.9 0.5 1.6 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 GAO89942.1 - 2.2e-175 583.1 4.2 2.6e-175 582.9 2.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAO89942.1 - 5.9e-09 36.2 1.4 5.8e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAO89942.1 - 7.1e-08 31.7 1.5 2.8e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 GAO89942.1 - 6e-06 25.3 0.5 1.1e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 GAO89942.1 - 2e-05 24.6 0.0 0.00033 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO89942.1 - 8.5e-05 22.7 0.0 0.08 13.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAO89942.1 - 0.00075 18.7 1.0 0.0098 15.0 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAO89942.1 - 0.0011 18.8 0.0 2.1 8.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 GAO89942.1 - 0.0052 16.5 0.1 0.7 9.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAO89942.1 - 0.01 15.3 0.1 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 GAO89942.1 - 0.011 15.1 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAO89942.1 - 0.021 14.5 2.3 0.083 12.6 0.3 2.8 2 2 1 3 3 3 0 Part of AAA domain Parvo_NS1 PF01057.12 GAO89942.1 - 0.051 12.4 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 GAO89942.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAO89942.1 - 0.083 12.4 0.2 0.15 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 GAO89943.1 - 3.7e-08 32.9 40.1 0.0061 15.7 2.4 5.6 1 1 4 6 6 6 5 Reovirus sigma C capsid protein IncA PF04156.9 GAO89943.1 - 3e-05 23.6 76.6 0.18 11.4 9.4 6.4 1 1 4 6 6 6 3 IncA protein Fib_alpha PF08702.5 GAO89943.1 - 0.0031 17.6 2.4 0.0031 17.6 1.6 7.0 2 2 4 7 7 7 1 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 GAO89943.1 - 0.0039 17.4 38.9 0.18 12.1 0.0 9.0 3 2 3 7 7 7 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAO89943.1 - 0.004 16.9 2.4 0.004 16.9 1.7 8.1 2 2 4 8 8 8 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 GAO89943.1 - 0.007 16.1 8.8 0.007 16.1 6.1 6.7 2 2 3 5 5 4 1 TPR/MLP1/MLP2-like protein EzrA PF06160.7 GAO89943.1 - 0.023 12.8 59.5 0.0092 14.2 7.0 5.1 1 1 2 3 3 2 0 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.6 GAO89943.1 - 0.024 14.0 50.3 0.026 13.9 2.0 7.3 3 3 4 7 7 7 0 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.5 GAO89943.1 - 0.036 14.2 0.6 0.036 14.2 0.4 7.2 5 1 2 7 7 7 0 Tup N-terminal DUF869 PF05911.6 GAO89943.1 - 0.069 11.3 60.6 0.26 9.4 17.8 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 GAO89943.1 - 0.12 10.8 61.4 0.037 12.4 6.1 3.7 1 1 3 4 4 4 0 AAA domain DUF2244 PF10003.4 GAO89943.1 - 0.22 10.9 0.3 0.42 9.9 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Filament PF00038.16 GAO89943.1 - 0.35 10.2 65.5 0.014 14.8 12.0 4.7 1 1 3 4 4 4 0 Intermediate filament protein DUF2730 PF10805.3 GAO89943.1 - 0.55 9.9 29.5 1.1 8.9 0.3 7.1 4 3 2 6 6 6 0 Protein of unknown function (DUF2730) DASH_Dam1 PF08653.5 GAO89943.1 - 1.5 8.6 23.5 3.1 7.6 0.1 8.2 8 1 1 9 9 9 0 DASH complex subunit Dam1 DUF948 PF06103.6 GAO89943.1 - 3.6 7.5 23.2 0.085 12.7 1.6 6.1 4 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 GAO89943.1 - 3.6 7.2 60.6 0.044 13.4 3.6 5.9 1 1 2 5 5 5 0 Mnd1 family Hemerythrin PF01814.18 GAO89943.1 - 5.2 7.2 16.1 1.3 9.1 1.1 5.2 4 2 1 5 5 5 0 Hemerythrin HHE cation binding domain MCPsignal PF00015.16 GAO89943.1 - 5.6 6.4 34.7 0.85 9.1 0.6 4.9 1 1 3 5 5 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 GAO89943.1 - 8.9 6.0 56.1 0.09 12.5 1.5 7.3 3 2 5 8 8 8 0 Laminin Domain II Abhydrolase_6 PF12697.2 GAO89944.1 - 6e-31 108.0 0.0 7.1e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO89944.1 - 3e-20 72.7 0.0 6.5e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO89944.1 - 5e-16 58.7 0.0 7.6e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAO89944.1 - 8.4e-12 45.1 0.1 1.2e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 GAO89944.1 - 0.00035 20.3 0.1 0.00071 19.3 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 GAO89944.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 GAO89944.1 - 0.0013 17.5 0.0 0.0029 16.4 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase Esterase PF00756.15 GAO89944.1 - 0.0052 16.2 0.1 0.056 12.8 0.1 2.1 1 1 0 1 1 1 1 Putative esterase DUF915 PF06028.6 GAO89944.1 - 0.0071 15.4 0.1 3.8 6.5 0.0 3.1 2 2 2 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 GAO89944.1 - 0.0082 16.3 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.7 GAO89944.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ndr PF03096.9 GAO89944.1 - 0.011 14.2 0.0 0.058 11.8 0.0 2.0 2 1 1 3 3 3 0 Ndr family DUF676 PF05057.9 GAO89944.1 - 0.011 14.9 0.3 0.019 14.2 0.2 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 GAO89944.1 - 0.012 14.5 0.3 0.019 13.8 0.2 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 GAO89944.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.4 GAO89944.1 - 0.026 13.4 0.0 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) LCAT PF02450.10 GAO89944.1 - 0.028 13.4 0.3 0.043 12.7 0.2 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 GAO89944.1 - 0.04 13.3 0.0 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) FAA_hydrolase PF01557.13 GAO89946.1 - 1.3e-50 171.8 0.0 1.8e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 GAO89947.1 - 1.2e-42 145.9 17.1 1.2e-42 145.9 11.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89947.1 - 2.8e-10 39.3 8.3 2.8e-10 39.3 5.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAO89947.1 - 1.4e-08 33.4 1.7 4.2e-05 21.9 0.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAO89948.1 - 1.5e-06 27.2 0.4 3.3e-06 26.1 0.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO89948.1 - 0.1 11.1 0.1 0.16 10.4 0.1 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter E2R135 PF11570.3 GAO89949.1 - 0.028 14.4 1.7 0.058 13.4 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Myb_DNA-bind_6 PF13921.1 GAO89949.1 - 0.99 9.5 4.3 0.28 11.3 0.5 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain 4HBT_3 PF13622.1 GAO89950.1 - 1.2e-36 126.8 0.2 1.4e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAO89950.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily p450 PF00067.17 GAO89954.1 - 1.2e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CVNH PF08881.5 GAO89955.1 - 1.6e-33 115.0 0.1 1.7e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 CVNH domain Img2 PF05046.9 GAO89955.1 - 0.12 12.5 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) F-box-like PF12937.2 GAO89956.1 - 0.0045 16.6 0.2 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 GAO89956.1 - 1.3 8.8 8.5 53 3.6 3.2 3.7 3 1 1 4 4 4 0 Leucine rich repeat Abp2 PF09441.5 GAO89957.1 - 1.2e-92 308.6 0.0 1.9e-92 307.9 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Herpes_UL45 PF05473.7 GAO89958.1 - 0.18 11.2 2.0 0.16 11.3 0.2 1.8 2 1 0 2 2 2 0 UL45 protein SAGA-Tad1 PF12767.2 GAO89958.1 - 0.59 9.7 5.2 0.76 9.3 3.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit eIF-3c_N PF05470.7 GAO89958.1 - 1.5 6.7 7.3 2.2 6.2 5.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2201_N PF13203.1 GAO89958.1 - 2.3 7.3 8.3 2.7 7.1 5.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Presenilin PF01080.12 GAO89958.1 - 2.6 6.7 8.8 3.3 6.4 6.1 1.1 1 0 0 1 1 1 0 Presenilin Herpes_DNAp_acc PF04929.7 GAO89958.1 - 2.8 6.7 9.9 3.3 6.5 6.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Dicty_REP PF05086.7 GAO89958.1 - 2.9 5.5 8.1 3.4 5.3 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.6 GAO89958.1 - 4.1 5.6 8.7 5.1 5.3 6.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2514 PF10721.4 GAO89958.1 - 4.6 6.9 13.2 0.3 10.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) SRP-alpha_N PF04086.8 GAO89958.1 - 6 6.1 13.6 7.2 5.9 9.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 GAO89958.1 - 6.4 4.9 12.3 7.3 4.7 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 GAO89958.1 - 7.1 6.0 12.5 8.6 5.7 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Brix PF04427.13 GAO89962.1 - 1.8e-30 106.0 0.0 2.3e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain PBP1_TM PF14812.1 GAO89962.1 - 2.8 8.3 5.8 0.45 10.8 0.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box PF00646.28 GAO89963.1 - 1e-05 25.0 1.8 0.00073 19.1 0.4 2.9 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 GAO89963.1 - 0.00011 21.8 0.4 0.00011 21.8 0.2 2.9 3 0 0 3 3 3 1 F-box-like DUF1838 PF08894.6 GAO89963.1 - 0.042 13.0 0.1 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Ras PF00071.17 GAO89964.1 - 2.3e-63 212.3 0.2 2.7e-63 212.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO89964.1 - 1.9e-21 76.7 0.1 2.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO89964.1 - 3e-13 49.3 0.1 3.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAO89964.1 - 5.4e-08 32.7 0.1 8.4e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAO89964.1 - 9e-05 21.7 0.2 0.00015 20.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAO89964.1 - 0.0001 22.4 0.1 0.00026 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 GAO89964.1 - 0.00012 21.5 0.1 0.00043 19.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 GAO89964.1 - 0.0009 18.3 0.0 0.0012 17.9 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 GAO89964.1 - 0.0011 18.8 0.1 0.0029 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAO89964.1 - 0.0027 16.9 0.1 0.0064 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 GAO89964.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 GAO89964.1 - 0.017 15.3 0.2 0.025 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 GAO89964.1 - 0.019 14.9 0.2 0.037 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 GAO89964.1 - 0.019 14.5 0.3 0.047 13.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain DUF4468 PF14730.1 GAO89964.1 - 0.054 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold FeoB_N PF02421.13 GAO89964.1 - 0.057 12.6 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B SpoIIID PF12116.3 GAO89964.1 - 0.095 12.6 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_29 PF13555.1 GAO89964.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 GAO89964.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 GAO89965.1 - 6.4e-08 32.1 1.1 1.4e-07 31.0 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DSRB PF10781.4 GAO89965.1 - 0.023 14.1 0.1 0.094 12.2 0.0 2.0 2 0 0 2 2 2 0 Dextransucrase DSRB AAA_2 PF07724.9 GAO89966.1 - 1.4e-38 132.5 0.0 1.7e-37 128.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) SLX9 PF15341.1 GAO89966.1 - 2.6e-29 102.1 11.1 2.6e-29 102.1 7.7 2.3 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 AAA PF00004.24 GAO89966.1 - 1e-14 54.8 0.0 2.8e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAO89966.1 - 1e-08 34.9 0.0 2.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 GAO89966.1 - 2.8e-06 27.1 0.0 8.3e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAO89966.1 - 0.00013 21.2 0.2 0.006 15.7 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 GAO89966.1 - 0.00019 21.5 0.3 0.0057 16.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAO89966.1 - 0.0003 20.8 1.4 0.00064 19.7 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain Sigma54_activat PF00158.21 GAO89966.1 - 0.00058 19.3 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 GAO89966.1 - 0.00088 20.0 0.2 0.0026 18.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 GAO89966.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 GAO89966.1 - 0.0093 15.5 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAO89966.1 - 0.019 14.0 0.1 0.19 10.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 GAO89966.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAO89966.1 - 0.049 13.9 0.4 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 GAO89966.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 GAO89966.1 - 0.051 13.2 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 GAO89966.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO89966.1 - 0.095 13.0 0.6 0.23 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain NAD_Gly3P_dh_N PF01210.18 GAO89967.1 - 1e-48 165.0 0.1 1.9e-48 164.1 0.0 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 GAO89967.1 - 4.4e-43 146.5 0.1 6.9e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 GAO89967.1 - 0.00059 20.2 0.0 0.37 11.2 0.0 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.1 GAO89968.1 - 1.5e-184 613.7 0.0 5.4e-184 611.9 0.0 1.8 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 GAO89968.1 - 6.1e-106 354.2 0.1 1.4e-105 353.0 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase DUF221 PF02714.10 GAO89968.1 - 6.9e-97 324.2 24.8 1.2e-96 323.3 17.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 hGDE_central PF14702.1 GAO89968.1 - 8.3e-89 297.1 0.0 1.3e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme RSN1_TM PF13967.1 GAO89968.1 - 2.2e-43 147.5 0.5 6.2e-43 146.0 0.3 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport hGDE_N PF14699.1 GAO89968.1 - 7.2e-25 86.6 0.0 1.7e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4463 PF14703.1 GAO89968.1 - 1.9e-22 79.5 0.8 4.4e-22 78.4 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Alpha-amylase PF00128.19 GAO89968.1 - 7.6e-05 22.2 0.1 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain RRM_6 PF14259.1 GAO89968.1 - 0.003 17.5 0.0 0.61 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 GAO89969.1 - 3e-08 33.2 0.1 8.5e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO89969.1 - 0.0084 15.7 0.2 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain DAHP_synth_1 PF00793.15 GAO89970.1 - 1.7e-100 335.2 0.0 2.1e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family ADH_zinc_N PF00107.21 GAO89972.1 - 1.1e-23 83.2 0.1 1.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO89972.1 - 2.2e-16 60.9 0.0 4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO89972.1 - 4.6e-12 45.6 0.0 6.2e-11 42.0 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF735 PF05246.6 GAO89972.1 - 0.016 14.9 0.1 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF735) AIG2_2 PF13772.1 GAO89973.1 - 0.0021 18.1 0.2 0.0085 16.1 0.1 1.9 1 1 0 1 1 1 1 AIG2-like family Cytochrom_C1 PF02167.10 GAO89974.1 - 8.9e-78 260.8 0.0 1.3e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAO89974.1 - 0.02 15.0 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAO89974.1 - 0.1 13.4 0.5 0.35 11.7 0.2 2.2 2 1 0 2 2 2 0 Cytochrome c AAA PF00004.24 GAO89975.1 - 6.6e-21 74.8 0.2 1.7e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sec10 PF07393.6 GAO89976.1 - 1.7e-190 634.8 1.9 2e-190 634.5 1.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 GAO89976.1 - 0.0065 16.1 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO89976.1 - 0.12 12.1 0.1 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like CAP PF00188.21 GAO89977.1 - 1.4e-18 67.6 4.6 2.4e-18 66.8 3.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family eIF2A PF08662.6 GAO89978.1 - 1.7e-39 135.5 6.7 7.5e-37 126.9 2.5 3.8 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 GAO89978.1 - 4.9e-08 32.7 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO89978.1 - 3.2e-07 30.2 0.0 1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO89978.1 - 5.1e-07 29.2 0.0 1.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAO89978.1 - 0.0002 21.0 0.1 0.098 12.5 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat IKI3 PF04762.7 GAO89978.1 - 0.014 13.2 0.6 0.022 12.5 0.0 1.5 2 0 0 2 2 2 0 IKI3 family RRM_2 PF04059.7 GAO89978.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif 2 Coatomer_WDAD PF04053.9 GAO89978.1 - 0.18 10.5 1.5 0.94 8.2 0.1 2.8 2 1 0 2 2 2 0 Coatomer WD associated region SWIB PF02201.13 GAO89979.1 - 9.3e-24 82.9 0.1 6.7e-23 80.1 0.0 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 GAO89979.1 - 1.7e-15 56.5 0.3 1.7e-15 56.5 0.2 2.3 3 0 0 3 3 3 1 DEK C terminal domain COX5A PF02284.11 GAO89979.1 - 0.076 12.9 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va SRP-alpha_N PF04086.8 GAO89979.1 - 0.73 9.1 14.0 1 8.7 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L18_c PF14204.1 GAO89979.1 - 1.9 9.1 5.2 1.8 9.1 1.9 2.2 2 1 0 2 2 2 0 Ribosomal L18 C-terminal region zf-C3HC4_3 PF13920.1 GAO89980.1 - 8.6e-06 25.3 9.7 8.6e-06 25.3 6.7 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.16 GAO89981.1 - 6.7e-76 254.7 0.1 1.1e-75 254.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAO89981.1 - 7.5e-38 130.3 2.1 7.5e-38 130.3 1.5 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 GAO89981.1 - 1.4e-09 38.0 0.2 1.4e-08 34.7 0.1 2.5 1 1 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAO89981.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 MutS domain II AAA_29 PF13555.1 GAO89981.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3972 PF13118.1 GAO89981.1 - 1.1 9.3 5.9 2.1 8.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) WD40 PF00400.27 GAO89982.1 - 2.2e-83 271.4 20.6 1.6e-14 53.1 0.0 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 GAO89982.1 - 2e-10 40.6 0.1 0.00089 19.0 0.0 3.6 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAO89982.1 - 3.9e-08 31.8 7.2 0.12 10.4 0.0 5.5 2 2 2 5 5 5 4 Nucleoporin Nup120/160 NLE PF08154.7 GAO89982.1 - 4.1e-05 23.4 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 GAO89982.1 - 0.021 14.8 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Velvet PF11754.3 GAO89984.1 - 9.8e-84 280.0 0.0 1.2e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Fungal_trans_2 PF11951.3 GAO89985.1 - 1.7e-09 36.7 2.4 1.7e-09 36.7 1.7 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain TP6A_N PF04406.9 GAO89985.1 - 0.054 13.1 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Type IIB DNA topoisomerase DUF3602 PF12223.3 GAO89986.1 - 1.7e-21 76.3 7.3 2.2e-19 69.6 0.5 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF3425 PF11905.3 GAO89987.1 - 9.9e-32 109.6 0.3 1.9e-31 108.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO89987.1 - 0.0015 18.4 12.3 0.077 12.9 0.1 2.3 2 0 0 2 2 2 2 bZIP transcription factor MFS_1 PF07690.11 GAO89988.1 - 3.9e-43 147.5 41.4 3.9e-43 147.5 28.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO89988.1 - 4e-09 35.5 33.2 1.1e-08 34.1 23.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_54 PF04666.8 GAO89989.1 - 4.1e-08 32.3 0.1 0.00016 20.5 0.1 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glucos_trans_II PF14264.1 GAO89989.1 - 0.013 14.5 0.2 0.013 14.5 0.1 1.9 2 0 0 2 2 2 0 Glucosyl transferase GtrII PTS_EIIA_2 PF00359.17 GAO89989.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 MFS_1 PF07690.11 GAO89989.1 - 0.24 10.0 3.4 0.1 11.3 0.8 1.4 2 0 0 2 2 2 0 Major Facilitator Superfamily DLH PF01738.13 GAO89990.1 - 2.7e-17 62.7 0.0 4.9e-13 48.8 0.0 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAO89990.1 - 2.2e-07 30.7 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ECH PF00378.15 GAO89991.1 - 6.5e-37 126.9 0.0 8.3e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pam17 PF08566.5 GAO89992.1 - 8.6e-74 246.9 0.0 1.2e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.3 GAO89993.1 - 2.9e-45 154.5 1.6 4.3e-45 153.9 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO89993.1 - 2.1e-09 37.1 11.6 3.8e-09 36.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 GAO89994.1 - 5.7e-09 35.7 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.11 GAO89995.1 - 1e-23 83.6 22.4 1.9e-23 82.7 15.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.7 GAO89997.1 - 1.6e-21 76.0 2.0 1.6e-21 76.0 1.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO89997.1 - 6.4e-15 54.8 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAO89997.1 - 0.00071 18.7 0.0 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAO89997.1 - 0.0015 18.1 0.1 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 GAO89997.1 - 0.031 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 GAO89998.1 - 1.8e-31 109.3 0.2 2.3e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO89998.1 - 1.9e-19 70.4 0.0 2.5e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO89998.1 - 5.4e-14 52.2 0.0 7.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO89998.1 - 7.1e-09 35.9 0.2 3.5e-08 33.6 0.1 2.0 1 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAO89998.1 - 4.8e-07 29.4 0.1 8.9e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAO89998.1 - 9.5e-06 24.9 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 GAO89998.1 - 2.8e-05 23.1 0.1 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAO89998.1 - 6.4e-05 22.3 0.2 0.0007 18.9 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAO89998.1 - 0.00059 18.8 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAO89998.1 - 0.0024 17.6 0.0 0.0063 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 GAO89998.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TMEM154 PF15102.1 GAO89999.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Synaptobrevin PF00957.16 GAO89999.1 - 0.0089 15.6 0.4 0.017 14.7 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin MpPF26 PF07666.6 GAO89999.1 - 0.037 13.9 1.4 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF3290 PF11694.3 GAO89999.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Pro_isomerase PF00160.16 GAO90000.1 - 4.6e-51 173.0 0.1 8.6e-51 172.2 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 GAO90000.1 - 1e-16 60.0 0.2 3.6e-07 29.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 GAO90001.1 - 9.1e-135 449.9 9.8 1.1e-134 449.7 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 GAO90001.1 - 0.13 11.6 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Glyco_hydro_76 PF03663.9 GAO90002.1 - 5.6e-147 489.9 23.6 6.8e-147 489.6 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 GAO90002.1 - 0.0002 21.2 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 Cloacin immunity protein CarbpepA_inh PF02977.10 GAO90002.1 - 0.074 12.6 1.9 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Pkinase PF00069.20 GAO90003.1 - 4.2e-42 144.1 0.0 7.6e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 GAO90003.1 - 1e-41 141.7 0.0 1.8e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 GAO90003.1 - 2.9e-19 69.1 0.0 8.9e-19 67.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 GAO90003.1 - 0.00042 19.7 0.0 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 GAO90003.1 - 0.055 12.9 0.2 0.66 9.3 0.1 2.2 1 1 1 2 2 2 0 PQQ-like domain Kdo PF06293.9 GAO90003.1 - 0.13 11.2 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAO90003.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cytokin_check_N PF10407.4 GAO90004.1 - 0.00012 21.6 0.0 0.00077 19.0 0.0 2.1 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus p450 PF00067.17 GAO90005.1 - 6.7e-62 209.5 0.0 8.6e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.14 GAO90006.1 - 1.7e-20 73.4 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF1196 PF06709.6 GAO90006.1 - 4.7 7.2 5.3 4 7.4 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1196) ADH_N PF08240.7 GAO90007.1 - 3.7e-24 84.5 0.4 3.7e-24 84.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO90007.1 - 4.4e-11 42.4 0.1 6.7e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Bac_rhamnosid PF05592.6 GAO90008.1 - 4.7e-31 107.5 0.1 6e-24 84.1 0.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 GAO90008.1 - 0.00088 18.0 0.2 0.0013 17.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 GAO90008.1 - 0.013 14.2 1.0 0.023 13.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Zn_clus PF00172.13 GAO90010.1 - 1.3e-07 31.3 6.6 1.3e-07 31.3 4.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1289 PF06945.8 GAO90010.1 - 0.048 13.1 4.5 0.078 12.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) MFS_1 PF07690.11 GAO90011.1 - 2.6e-28 98.7 24.6 2.6e-28 98.7 17.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90011.1 - 3.5e-12 45.6 13.9 3.5e-12 45.6 9.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter ADH_zinc_N PF00107.21 GAO90011.1 - 7.7e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90011.1 - 5.3e-05 22.9 0.0 0.00019 21.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain OATP PF03137.15 GAO90011.1 - 0.00023 19.3 0.8 0.046 11.7 0.2 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Kinesin PF00225.18 GAO90012.1 - 1.2e-51 175.4 0.0 5.5e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AAA_16 PF13191.1 GAO90012.1 - 0.12 12.3 0.8 0.71 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain NAD_binding_10 PF13460.1 GAO90013.1 - 5.9e-14 52.4 0.1 1.3e-13 51.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAO90013.1 - 1.6e-13 50.4 0.1 2.8e-13 49.6 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAO90013.1 - 3.6e-08 32.7 0.2 5e-08 32.3 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAO90013.1 - 1.3e-05 24.7 0.1 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO90013.1 - 0.00024 19.9 0.1 0.00051 18.8 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAO90013.1 - 0.0005 20.0 0.2 0.0011 18.9 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 GAO90013.1 - 0.0012 18.7 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 GAO90013.1 - 0.0017 18.5 0.1 0.0058 16.7 0.1 1.9 1 1 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 GAO90013.1 - 0.003 18.0 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.7 GAO90013.1 - 0.0047 15.8 0.1 0.0082 15.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 GAO90013.1 - 0.0084 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.11 GAO90013.1 - 0.012 15.0 0.1 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 GAO90013.1 - 0.1 12.2 0.4 0.22 11.1 0.3 1.6 1 1 0 1 1 1 0 KR domain p450 PF00067.17 GAO90015.1 - 4.6e-69 233.1 0.0 8.1e-69 232.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 GAO90016.1 - 5.3e-44 150.2 0.0 1.1e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAO90016.1 - 1.1e-27 96.8 0.0 1.8e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAO90016.1 - 1.3e-19 70.8 0.0 2.9e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fungal_trans_2 PF11951.3 GAO90017.1 - 2.1e-09 36.4 0.1 3.6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO90018.1 - 2e-96 323.3 25.9 2.5e-96 323.0 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90018.1 - 6.6e-22 77.7 39.8 3.3e-15 55.6 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF89 PF01937.14 GAO90019.1 - 2.3e-107 358.8 0.1 2.6e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sugar_tr PF00083.19 GAO90020.1 - 3.2e-77 260.0 20.5 3.7e-77 259.8 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90020.1 - 6.4e-28 97.4 43.9 6.6e-24 84.2 20.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAO90020.1 - 0.0001 22.0 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 MFS_1 like family DUF1228 PF06779.9 GAO90020.1 - 0.0088 16.0 1.4 0.0088 16.0 1.0 3.3 2 2 1 4 4 4 1 Protein of unknown function (DUF1228) UPF0075 PF03702.9 GAO90021.1 - 8.6e-74 248.6 0.0 1.1e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) ADH_zinc_N PF00107.21 GAO90021.1 - 4.5e-24 84.4 0.5 8.7e-24 83.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90021.1 - 1.5e-21 76.2 0.6 3.1e-21 75.1 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO90021.1 - 7.5e-06 26.8 0.0 1.9e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_transf_90 PF05686.7 GAO90022.1 - 3.7e-15 55.5 0.8 1.3e-13 50.4 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 90 MAP7 PF05672.6 GAO90024.1 - 0.23 10.8 51.3 0.56 9.5 11.1 2.1 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family rRNA_processing PF08524.6 GAO90024.1 - 5.1 6.8 32.4 8.2 6.2 22.5 1.3 1 0 0 1 1 1 0 rRNA processing FAD_binding_7 PF03441.9 GAO90026.1 - 6.5e-98 327.3 0.1 1.1e-97 326.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAO90026.1 - 2.3e-42 144.5 0.3 3.9e-42 143.7 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.13 GAO90027.1 - 1e-22 80.2 0.0 2.4e-22 79.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90027.1 - 1.1e-09 38.0 11.1 2e-09 37.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorion_2 PF03964.10 GAO90028.1 - 0.016 15.6 9.1 0.11 13.0 2.6 2.7 2 0 0 2 2 2 0 Chorion family 2 Zn_clus PF00172.13 GAO90029.1 - 9.6e-06 25.4 13.5 9.6e-06 25.4 9.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAO90029.1 - 6e-05 21.8 0.1 0.00021 20.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 GAO90030.1 - 2e-42 145.3 0.1 2.7e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Exo_endo_phos PF03372.18 GAO90031.1 - 4.7e-09 36.5 0.6 7.7e-09 35.8 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 GAO90031.1 - 2.8e-05 23.9 0.2 7.2e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Jacalin-like lectin domain GrpB PF04229.9 GAO90032.1 - 2e-51 173.9 0.0 2.4e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Lys PF00062.15 GAO90033.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family adh_short PF00106.20 GAO90034.1 - 7.8e-13 48.6 0.4 1.3e-12 47.9 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90034.1 - 7.8e-07 28.9 0.2 1.3e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 KR domain TPR_12 PF13424.1 GAO90035.1 - 1.4e-09 37.7 12.4 0.00012 21.9 0.0 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat AAA_16 PF13191.1 GAO90035.1 - 1.9e-05 24.7 0.0 1.9e-05 24.7 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 GAO90035.1 - 0.00028 21.0 0.6 0.011 15.8 0.0 4.0 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.22 GAO90035.1 - 0.022 15.0 0.1 0.16 12.2 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 GAO90035.1 - 0.027 15.2 0.1 0.31 11.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain TPR_2 PF07719.12 GAO90035.1 - 8.5 6.5 8.6 1.8 8.7 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PTR2 PF00854.16 GAO90036.1 - 3.3e-41 141.3 15.8 4e-40 137.7 7.3 3.1 1 1 1 2 2 2 2 POT family Flu_NP PF00506.13 GAO90036.1 - 0.11 10.9 0.1 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Bac_rhodopsin PF01036.13 GAO90037.1 - 4.3e-35 121.0 19.1 5.8e-35 120.6 13.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Lactamase_B_2 PF12706.2 GAO90038.1 - 6e-23 81.3 0.0 7.2e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO90038.1 - 1.4e-11 44.4 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAO90038.1 - 0.011 15.4 0.7 0.032 13.9 0.5 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Abhydrolase_6 PF12697.2 GAO90039.1 - 3.3e-07 30.4 0.2 1.5e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 GAO90040.1 - 3.5e-30 104.7 0.0 2.9e-29 101.6 0.0 1.9 2 0 0 2 2 2 2 AMP-binding enzyme F-box PF00646.28 GAO90042.1 - 1.7e-06 27.5 0.4 4.4e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO90042.1 - 0.0027 17.3 0.2 0.0064 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 GAO90042.1 - 0.051 13.2 0.2 7 6.3 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Gly_transf_sug PF04488.10 GAO90044.1 - 5.1e-10 39.6 0.0 9.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GST_N_3 PF13417.1 GAO90045.1 - 8e-10 38.8 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO90045.1 - 1.9e-09 37.5 0.0 5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO90045.1 - 4.6e-09 36.1 0.0 7.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO90045.1 - 4.3e-07 29.8 0.0 8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO90045.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO90045.1 - 1.4e-06 28.1 0.6 2.7e-06 27.1 0.4 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_2_3 PF13632.1 GAO90046.1 - 0.0071 16.0 0.6 0.012 15.3 0.4 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 COX14 PF14880.1 GAO90046.1 - 0.19 11.3 0.3 0.36 10.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly adh_short PF00106.20 GAO90049.1 - 5.6e-23 81.6 0.0 7.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90049.1 - 9.6e-13 48.4 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAO90049.1 - 1.3e-07 31.8 0.0 4.1e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 GAO90049.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 GAO90049.1 - 0.00029 19.9 0.1 0.00047 19.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAO90049.1 - 0.00055 20.0 0.1 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 GAO90049.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 GAO90049.1 - 0.0026 17.1 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 GAO90049.1 - 0.017 15.5 0.2 0.092 13.1 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAO90049.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Psu PF07455.6 GAO90049.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) NmrA PF05368.8 GAO90049.1 - 0.092 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Wax2_C PF12076.3 GAO90049.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain 3HCDH_N PF02737.13 GAO90049.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Beta_helix PF13229.1 GAO90050.1 - 0.001 18.8 16.6 0.25 11.0 2.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_28 PF00295.12 GAO90050.1 - 0.01 14.8 2.2 0.034 13.1 1.4 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 28 COesterase PF00135.23 GAO90051.1 - 1.1e-78 265.3 0.0 1.2e-75 255.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90051.1 - 2e-06 27.5 0.1 5.4e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO90051.1 - 0.0018 17.5 0.2 0.0018 17.5 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAO90051.1 - 0.015 15.0 2.7 0.24 11.1 1.9 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Alginate_lyase PF05426.7 GAO90052.1 - 7.9e-22 77.8 4.7 2.2e-21 76.4 3.3 1.6 1 1 0 1 1 1 1 Alginate lyase MFS_1 PF07690.11 GAO90053.1 - 7.5e-31 107.1 25.7 7.5e-31 107.1 17.8 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO90053.1 - 0.00022 19.6 3.3 0.00035 18.9 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAO90054.1 - 1.6e-32 112.6 29.0 2.2e-32 112.1 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 GAO90054.1 - 0.072 13.5 0.5 0.32 11.4 0.2 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 GAO90055.1 - 1.9e-19 69.8 0.3 2.7e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 GAO90056.1 - 3.7e-21 75.1 0.1 6.4e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90056.1 - 2.9e-09 36.6 10.6 5.8e-09 35.7 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transposase_28 PF04195.7 GAO90056.1 - 0.041 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon Glyco_hydro_43 PF04616.9 GAO90057.1 - 2.6e-69 233.4 4.7 3.2e-69 233.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Alginate_lyase PF05426.7 GAO90058.1 - 7.9e-05 22.1 11.1 0.0002 20.8 7.7 1.6 1 1 0 1 1 1 1 Alginate lyase DUF2461 PF09365.5 GAO90058.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) OTCace PF00185.19 GAO90058.1 - 0.11 12.3 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Fasciclin PF02469.17 GAO90059.1 - 7.5e-17 61.5 0.0 1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Med8 PF10232.4 GAO90059.1 - 0.2 11.1 0.4 0.32 10.4 0.3 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Melibiase PF02065.13 GAO90060.1 - 3.6e-22 78.5 0.1 6.9e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 GAO90060.1 - 0.04 13.0 0.0 0.093 11.8 0.0 1.5 2 0 0 2 2 2 0 Glycoside hydrolase 97 FAD_binding_4 PF01565.18 GAO90061.1 - 2e-18 66.2 1.7 2e-18 66.2 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO90061.1 - 4.6e-08 32.8 1.2 4.6e-08 32.8 0.8 2.0 2 0 0 2 2 2 1 Berberine and berberine like Thioredoxin PF00085.15 GAO90061.1 - 4e-05 23.2 0.0 7.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pectate_lyase PF03211.8 GAO90064.1 - 5.2e-79 264.6 4.0 6.2e-79 264.3 2.8 1.0 1 0 0 1 1 1 1 Pectate lyase Fungal_trans_2 PF11951.3 GAO90065.1 - 6.4e-10 38.1 8.0 1.2e-06 27.4 5.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain NIT PF08376.5 GAO90065.1 - 0.1 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing AP_endonuc_2 PF01261.19 GAO90066.1 - 1.6e-21 76.6 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 GAO90067.1 - 5.5e-41 140.4 62.9 2.4e-37 128.5 34.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DAHP_synth_1 PF00793.15 GAO90068.1 - 1.1e-82 276.8 0.0 1.3e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cupin_2 PF07883.6 GAO90069.1 - 0.0072 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Cupin domain GFO_IDH_MocA PF01408.17 GAO90070.1 - 6.7e-18 65.3 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAO90070.1 - 0.057 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 GAO90070.1 - 0.078 13.3 0.1 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.13 GAO90071.1 - 1.3e-15 57.0 0.5 2.2e-15 56.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90071.1 - 4.6e-08 32.8 12.7 9.1e-08 31.8 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 GAO90072.1 - 1e-28 100.1 0.0 1.6e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAO90072.1 - 9.5e-06 25.4 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAO90072.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 GAO90072.1 - 0.039 14.5 0.1 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 GAO90072.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 GAO90073.1 - 9.9e-58 195.7 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3632 PF12311.3 GAO90074.1 - 1.5e-20 73.7 9.0 9.9e-20 71.1 6.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.13 GAO90075.1 - 7.7e-32 110.1 3.0 1.3e-31 109.4 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribonuclease PF00545.15 GAO90075.1 - 6.3e-09 35.7 0.1 1.6e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 ribonuclease Metal_resist PF13801.1 GAO90075.1 - 0.011 15.7 0.1 0.061 13.3 0.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Oxidored_q6 PF01058.17 GAO90076.1 - 3.6e-24 84.8 0.0 5.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Abhydrolase_3 PF07859.8 GAO90077.1 - 1.5e-55 188.0 0.1 2.2e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAO90077.1 - 3.3e-09 36.0 0.0 5.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAO90077.1 - 6.1e-07 29.2 0.0 9.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO90077.1 - 2.1e-05 24.5 0.6 3.3e-05 23.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO90077.1 - 0.026 13.0 0.0 0.043 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 GAO90077.1 - 0.18 10.4 0.0 0.57 8.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) SnoaL_2 PF12680.2 GAO90078.1 - 0.00021 21.6 0.1 0.00027 21.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 GAO90078.1 - 0.029 14.2 0.2 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Lactamase_B PF00753.22 GAO90079.1 - 1.3e-21 77.1 0.3 1.7e-21 76.7 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAO90079.1 - 6e-06 25.9 0.0 9.5e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAO90079.1 - 0.0037 16.9 0.1 0.0076 15.9 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_5 PF12695.2 GAO90080.1 - 1.9e-19 69.8 0.0 3.1e-19 69.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO90080.1 - 1.4e-18 67.6 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAO90080.1 - 3.7e-08 32.2 0.1 5e-06 25.2 0.1 2.8 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 GAO90080.1 - 2.3e-05 23.9 0.1 3.8e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 GAO90080.1 - 3.9e-05 23.4 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 GAO90080.1 - 0.00036 20.3 0.0 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAO90080.1 - 0.0062 15.7 0.3 0.056 12.6 0.0 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 GAO90080.1 - 0.11 10.7 0.0 6.5 4.9 0.0 2.6 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 GAO90080.1 - 0.13 11.5 0.0 0.85 8.8 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family ADH_zinc_N PF00107.21 GAO90081.1 - 1.3e-10 40.9 0.0 2.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90081.1 - 1.3e-10 40.9 0.0 8e-10 38.4 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO90081.1 - 7.2e-08 33.3 0.0 1.3e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAO90081.1 - 0.0074 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 GAO90081.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ERG4_ERG24 PF01222.12 GAO90082.1 - 1.1e-148 495.3 4.9 1.2e-148 495.2 3.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAO90082.1 - 7.5e-05 22.1 0.4 0.00019 20.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Dyp_perox PF04261.7 GAO90084.1 - 0.0013 17.4 0.0 0.23 10.1 0.0 2.6 3 0 0 3 3 3 2 Dyp-type peroxidase family DUF1929 PF09118.6 GAO90085.1 - 1.6e-25 89.0 0.0 3.3e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 GAO90085.1 - 1.5e-18 66.9 0.0 5.1e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain Kelch_1 PF01344.20 GAO90085.1 - 1.6e-07 30.7 3.7 0.00074 19.0 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAO90085.1 - 2.1e-06 27.2 5.5 0.88 9.4 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.6 GAO90085.1 - 6e-06 25.5 0.6 0.085 11.9 0.2 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.1 GAO90085.1 - 9.9e-06 25.2 16.9 0.00015 21.4 0.0 4.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO90085.1 - 1.8e-05 24.7 5.8 0.0043 17.1 0.0 4.8 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.1 GAO90085.1 - 0.0033 17.3 6.0 4.4 7.3 0.0 4.4 4 0 0 4 4 4 1 Kelch motif APC10 PF03256.11 GAO90085.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Kelch_3 PF13415.1 GAO90085.1 - 0.68 10.1 3.7 30 4.9 0.0 4.2 4 2 0 4 4 4 0 Galactose oxidase, central domain MFS_1 PF07690.11 GAO90086.1 - 9.3e-21 73.9 75.6 2.9e-14 52.5 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAO90087.1 - 2.6e-11 42.8 0.1 4.5e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90087.1 - 3.9e-08 33.0 9.3 8.3e-08 32.0 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.13 GAO90088.1 - 3.3e-39 134.7 0.0 4.7e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.4 GAO90088.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 COesterase PF00135.23 GAO90089.1 - 3.1e-95 319.9 0.0 3.6e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90089.1 - 1.7e-08 34.3 0.0 4.4e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO90089.1 - 0.0016 17.6 0.1 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 GAO90089.1 - 0.018 13.6 0.0 0.052 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 GAO90090.1 - 4.6e-16 58.4 0.0 6.6e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90090.1 - 0.01 15.7 1.3 0.023 14.5 0.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 GAO90091.1 - 2.5e-69 233.5 0.0 3.2e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAO90091.1 - 5.8e-63 212.4 0.0 8.7e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAO90091.1 - 3.3e-21 75.0 0.5 3.3e-21 75.0 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 GAO90091.1 - 0.0061 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain Sugar_tr PF00083.19 GAO90092.1 - 5.6e-81 272.4 29.9 6.8e-81 272.1 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90092.1 - 4.5e-24 84.8 37.1 1.2e-23 83.4 19.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO90092.1 - 1.4e-05 23.7 23.0 8.3e-05 21.1 5.9 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein Fungal_trans PF04082.13 GAO90094.1 - 1.5e-06 27.2 0.2 2.7e-05 23.2 0.0 2.7 2 1 0 3 3 3 1 Fungal specific transcription factor domain adh_short PF00106.20 GAO90095.1 - 9.3e-13 48.4 0.1 4.2e-12 46.3 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO90095.1 - 3.2e-05 23.6 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO90095.1 - 0.00049 19.6 0.1 0.00083 18.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO90095.1 - 0.0005 20.1 0.2 0.0011 19.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO90095.1 - 0.00057 18.8 0.0 0.001 18.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 GAO90095.1 - 0.00062 19.8 0.1 0.00097 19.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAO90095.1 - 0.0061 15.5 0.1 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 GAO90095.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 GAO90095.1 - 0.013 14.7 0.1 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family TIR-like PF10137.4 GAO90095.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Polysacc_synt_2 PF02719.10 GAO90095.1 - 0.063 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 GAO90095.1 - 0.065 12.8 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 GAO90095.1 - 0.069 12.9 0.3 0.13 12.0 0.2 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Prp19 PF08606.6 GAO90095.1 - 0.11 12.1 0.4 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Catalase PF00199.14 GAO90096.1 - 1.4e-170 567.0 0.1 1.8e-170 566.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAO90096.1 - 1.1e-13 50.8 0.1 2.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.14 GAO90097.1 - 9.9e-52 175.9 0.0 1.3e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO90097.1 - 3e-36 124.8 0.0 4.9e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAO90097.1 - 0.0012 17.8 0.1 0.0023 16.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAO90097.1 - 0.005 15.7 0.1 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO90097.1 - 0.0082 15.0 0.7 0.073 11.9 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAO90097.1 - 0.022 13.8 0.5 0.039 13.0 0.1 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 GAO90097.1 - 0.034 14.1 0.4 0.079 12.9 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAO90097.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAO90097.1 - 0.069 13.2 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase His_Phos_2 PF00328.17 GAO90098.1 - 2.5e-08 33.6 0.0 4.4e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MOSC PF03473.12 GAO90099.1 - 5.8e-07 29.0 0.6 2.8e-06 26.8 0.4 2.0 1 1 0 1 1 1 1 MOSC domain Catalase PF00199.14 GAO90100.1 - 4.5e-164 545.7 3.3 3.3e-126 421.0 0.0 2.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 GAO90100.1 - 1.3e-14 53.8 0.3 3.5e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Brix PF04427.13 GAO90100.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Brix domain AMIN PF11741.3 GAO90100.1 - 0.15 12.0 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 AMIN domain Oxidored_molyb PF00174.14 GAO90101.1 - 1.4e-46 158.0 0.0 2.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAO90101.1 - 1.5e-23 82.8 3.2 3.2e-23 81.8 2.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 GAO90101.1 - 0.061 13.2 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 SLBB domain Mob_synth_C PF06463.8 GAO90102.1 - 2.3e-34 117.8 0.1 7.6e-33 112.9 0.1 2.3 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAO90102.1 - 2.7e-13 50.4 0.0 4.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily GMC_oxred_N PF00732.14 GAO90103.1 - 4.9e-54 183.4 0.0 6.3e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO90103.1 - 5.3e-35 120.8 0.0 8.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO90103.1 - 3.7e-05 22.7 0.7 0.064 12.0 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 GAO90103.1 - 0.0073 15.2 0.4 0.013 14.4 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAO90103.1 - 0.0091 15.9 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO90103.1 - 0.013 14.5 0.6 0.025 13.7 0.1 1.7 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 GAO90103.1 - 0.016 14.1 0.3 0.047 12.5 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90103.1 - 0.074 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.14 GAO90104.1 - 1.3e-161 537.6 2.2 6.5e-160 531.9 1.5 2.0 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAO90104.1 - 4.7e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans_2 PF11951.3 GAO90105.1 - 7.4e-15 54.4 2.8 1.6e-14 53.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF1151 PF06625.6 GAO90106.1 - 0.062 13.0 4.7 0.071 12.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Dyp_perox PF04261.7 GAO90107.1 - 9.1e-89 297.2 0.0 1e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Cellulase PF00150.13 GAO90108.1 - 4e-32 111.5 0.0 7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 GAO90108.1 - 0.1 13.0 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like LigB PF02900.13 GAO90108.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Zn_clus PF00172.13 GAO90109.1 - 2.2e-08 33.8 7.3 5.6e-08 32.5 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO90109.1 - 2.2e-06 26.7 0.4 6.4e-06 25.2 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAO90110.1 - 2.4e-77 260.4 22.4 2.8e-77 260.2 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90110.1 - 1.2e-26 93.2 45.9 1.6e-20 73.1 20.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO90110.1 - 1.2e-07 30.4 18.1 0.00027 19.4 5.2 3.6 1 1 2 3 3 3 3 MFS/sugar transport protein ABC_tran PF00005.22 GAO90111.1 - 3.3e-07 30.6 0.0 3.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 GAO90111.1 - 0.012 15.5 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAO90111.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 GAO90111.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAO90111.1 - 0.041 13.7 0.0 0.066 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAO90111.1 - 0.057 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 GAO90111.1 - 0.062 12.9 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 GAO90111.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAO90111.1 - 0.13 13.0 0.0 0.21 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Kdo_hydroxy PF11004.3 GAO90112.1 - 0.062 12.2 0.1 0.097 11.6 0.1 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase NUDIX PF00293.23 GAO90113.1 - 1.5e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3704 PF12488.3 GAO90113.1 - 0.1 12.2 1.8 0.18 11.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) MFS_1 PF07690.11 GAO90115.1 - 1.4e-29 102.9 37.8 1.4e-29 102.9 26.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_hydroxylase PF04116.8 GAO90116.1 - 2.3e-05 24.7 0.3 2.3e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 GAO90116.1 - 0.0048 16.8 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 GAO90116.1 - 0.0095 15.3 0.1 0.031 13.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO90116.1 - 0.12 12.3 0.1 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding FAD_binding_2 PF00890.19 GAO90117.1 - 4.6e-80 269.5 0.1 5.4e-80 269.2 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90117.1 - 1.1e-06 27.8 0.4 0.00035 19.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAO90117.1 - 1.2e-05 24.6 0.3 1.8e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90117.1 - 7.4e-05 22.7 0.4 0.0044 16.9 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO90117.1 - 0.0012 17.3 0.6 0.0033 15.9 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAO90117.1 - 0.0044 17.0 1.1 0.013 15.4 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO90117.1 - 0.005 15.9 0.2 0.013 14.6 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Ank_2 PF12796.2 GAO90118.1 - 2.9e-167 543.5 37.3 3e-22 78.7 0.2 8.9 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAO90118.1 - 1.3e-129 416.0 35.3 1.5e-08 34.0 0.1 18.2 18 0 0 18 18 18 18 Ankyrin repeat Ank_4 PF13637.1 GAO90118.1 - 8.5e-112 363.8 23.3 1.5e-10 41.2 0.1 14.7 3 2 14 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO90118.1 - 3.2e-99 314.7 12.6 5.7e-06 26.0 0.0 18.3 18 0 0 18 18 18 17 Ankyrin repeat Ank_5 PF13857.1 GAO90118.1 - 5.9e-94 305.9 27.8 4.6e-10 39.4 0.0 15.7 1 1 16 17 17 17 17 Ankyrin repeats (many copies) DUF1110 PF06533.7 GAO90118.1 - 0.0094 15.7 14.6 0.046 13.5 0.1 5.5 5 1 0 6 6 6 1 Protein of unknown function (DUF1110) Nitro_FeMo-Co PF02579.12 GAO90118.1 - 0.17 11.9 1.0 5.7 7.0 0.0 3.8 4 1 1 5 5 5 0 Dinitrogenase iron-molybdenum cofactor Abhydrolase_6 PF12697.2 GAO90119.1 - 8.8e-29 100.9 0.2 1.1e-28 100.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO90119.1 - 1.7e-10 40.8 0.1 4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO90119.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hemerythrin PF01814.18 GAO90122.1 - 1.2e-11 44.8 0.1 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MinC_N PF05209.8 GAO90122.1 - 0.0024 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain DUF1449 PF07290.6 GAO90123.1 - 0.08 12.2 0.1 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF3377 PF11857.3 GAO90123.1 - 0.17 11.5 1.2 0.22 11.1 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1929 PF09118.6 GAO90124.1 - 5.1e-27 93.8 0.0 1.2e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 GAO90124.1 - 1e-18 67.3 1.1 2.8e-18 65.9 0.7 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.1 GAO90124.1 - 1e-10 41.3 4.5 0.0069 16.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 GAO90124.1 - 1.3e-10 40.7 0.9 3.2e-06 26.4 0.4 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_1 PF01344.20 GAO90124.1 - 1e-08 34.5 0.7 0.11 12.1 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAO90124.1 - 3.7e-07 29.7 13.1 0.017 14.8 0.1 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain APC10 PF03256.11 GAO90124.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Kelch_3 PF13415.1 GAO90124.1 - 0.033 14.3 9.8 0.13 12.4 0.2 4.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO90124.1 - 0.043 13.7 3.8 3.1 7.8 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Aminotran_3 PF00202.16 GAO90125.1 - 1.5e-80 270.5 0.0 1.8e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAO90125.1 - 0.073 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II HAD PF12710.2 GAO90126.1 - 0.00041 20.5 0.0 0.00045 20.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAO90126.1 - 0.0031 16.8 0.0 0.0039 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 GAO90126.1 - 0.0036 17.5 0.0 0.0054 16.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Dyp_perox PF04261.7 GAO90127.1 - 2e-10 39.9 0.0 1.5e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Dyp-type peroxidase family NUDIX-like PF09296.6 GAO90127.1 - 0.038 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain RNase_H PF00075.19 GAO90129.1 - 5e-14 52.7 0.0 1.4e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 RNase H DUF4246 PF14033.1 GAO90130.1 - 2.1e-33 115.7 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Sugar_tr PF00083.19 GAO90131.1 - 2.7e-70 237.2 22.6 3.2e-70 236.9 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90131.1 - 7.6e-17 61.0 26.6 5.9e-15 54.8 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3716 PF12511.3 GAO90132.1 - 0.00039 19.9 0.1 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) F-box-like PF12937.2 GAO90133.1 - 0.00014 21.5 0.0 0.0006 19.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO90133.1 - 0.014 15.0 0.0 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain ABC2_membrane PF01061.19 GAO90134.1 - 2.7e-86 288.0 44.6 3.1e-44 150.6 13.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAO90134.1 - 1.1e-37 129.3 0.0 1.5e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAO90134.1 - 1e-29 102.2 0.0 5.8e-24 83.7 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAO90134.1 - 6.6e-12 45.1 30.5 4.4e-06 25.9 3.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAO90134.1 - 9.2e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 GAO90134.1 - 2.7e-05 23.4 0.3 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAO90134.1 - 8.2e-05 22.0 0.0 0.0037 16.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAO90134.1 - 0.00095 19.2 2.2 0.024 14.6 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.4 GAO90134.1 - 0.0028 17.1 0.4 1.6 8.2 0.2 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 GAO90134.1 - 0.0035 17.4 0.2 0.14 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAO90134.1 - 0.0087 15.5 0.5 0.077 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 GAO90134.1 - 0.0096 15.3 1.8 0.44 9.9 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 GAO90134.1 - 0.029 14.3 3.2 0.4 10.6 0.5 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 GAO90134.1 - 0.03 15.1 0.0 1.1 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAO90134.1 - 0.052 13.4 0.0 9.7 6.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 GAO90134.1 - 0.066 13.5 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO90134.1 - 0.073 12.9 0.0 0.54 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 GAO90134.1 - 0.082 12.8 0.0 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 GAO90134.1 - 0.12 11.5 0.1 0.84 8.8 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 GAO90134.1 - 0.16 11.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 GAO90134.1 - 0.26 10.9 1.1 4.5 6.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 TPMT PF05724.6 GAO90135.1 - 4.3e-28 98.2 0.0 6.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 GAO90135.1 - 2.4e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90135.1 - 5.1e-05 23.6 0.0 9.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90135.1 - 0.00027 20.5 0.0 0.00058 19.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90135.1 - 0.0046 16.6 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAO90135.1 - 0.038 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB bZIP_1 PF00170.16 GAO90136.1 - 3.6e-06 26.8 2.4 6.7e-06 25.9 1.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 GAO90136.1 - 0.02 14.4 0.1 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Ank_2 PF12796.2 GAO90138.1 - 1.2e-72 240.2 22.4 1.2e-17 63.9 0.1 7.1 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAO90138.1 - 1.3e-50 166.7 20.7 2.1e-09 36.7 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.1 GAO90138.1 - 2.9e-46 150.8 5.8 6.7e-06 25.8 0.0 12.9 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 GAO90138.1 - 1.4e-45 152.8 7.3 3.7e-12 46.3 0.1 8.7 6 2 4 10 10 10 9 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 GAO90138.1 - 1.3e-40 139.9 1.1 3.5e-39 135.2 0.2 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Ank_5 PF13857.1 GAO90138.1 - 1.4e-34 117.3 13.9 4.1e-06 26.8 0.0 10.0 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Glyco_hydro_85 PF03644.8 GAO90138.1 - 0.0059 15.7 0.0 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 Glyco_hydro_32C PF08244.7 GAO90139.1 - 2.2e-14 53.5 0.0 5.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 GAO90139.1 - 5.5e-14 52.2 0.0 7.9e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain TPT PF03151.11 GAO90139.1 - 4.4e-10 39.4 2.6 7.4e-10 38.6 1.8 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 GAO90139.1 - 0.00023 20.1 2.5 0.0003 19.7 1.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAO90139.1 - 0.0039 17.2 5.1 0.0039 17.2 3.5 1.8 2 0 0 2 2 2 1 EamA-like transporter family COesterase PF00135.23 GAO90140.1 - 2.5e-86 290.5 0.0 3.4e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90140.1 - 9e-07 28.6 0.3 4.6e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAO90140.1 - 0.033 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 GAO90142.1 - 1.4e-06 27.1 0.1 2.8e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain YhzD PF14120.1 GAO90143.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 YhzD-like protein TPR_10 PF13374.1 GAO90144.1 - 2.1e-68 224.5 1.1 1.5e-14 53.3 0.0 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAO90144.1 - 2.3e-61 203.6 0.5 1.1e-17 63.7 0.0 5.2 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAO90144.1 - 2.3e-20 70.7 6.4 0.003 17.2 0.0 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAO90144.1 - 1.3e-16 59.9 0.6 6.9e-05 22.4 0.1 5.6 3 1 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 GAO90144.1 - 5.6e-16 57.0 3.7 0.076 12.9 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAO90144.1 - 2.4e-15 55.3 2.7 0.2 11.9 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAO90144.1 - 1.1e-14 53.3 2.5 0.27 10.9 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAO90144.1 - 9.4e-14 51.6 1.8 0.00057 20.4 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAO90144.1 - 2.6e-11 42.9 0.0 4.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 GAO90144.1 - 1.4e-10 40.5 0.0 3.3e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_4 PF07721.9 GAO90144.1 - 6.8e-09 35.3 8.5 0.45 11.0 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAO90144.1 - 1.6e-08 34.7 9.7 0.026 14.8 0.1 6.6 3 1 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO90144.1 - 8.2e-08 32.2 0.1 0.26 11.4 0.0 4.5 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 GAO90144.1 - 5.7e-07 29.6 0.1 5.6e-06 26.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.1 GAO90144.1 - 1.5e-06 28.3 9.3 1.3 9.8 0.1 7.1 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO90144.1 - 1.8e-06 27.2 1.9 22 5.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAO90144.1 - 5.7e-06 26.4 0.0 2.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF4074 PF13293.1 GAO90144.1 - 8.8e-06 25.8 0.0 4.3 7.6 0.0 5.6 6 0 0 6 6 5 1 Domain of unknown function (DUF4074) NACHT PF05729.7 GAO90144.1 - 9.8e-06 25.3 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.1 GAO90144.1 - 0.00024 21.3 13.8 3.1 8.4 0.1 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAO90144.1 - 0.00038 20.2 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 GAO90144.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain HSA PF07529.8 GAO90144.1 - 0.0066 16.2 2.3 7.1 6.4 0.0 4.5 3 1 1 4 4 4 0 HSA SRP54 PF00448.17 GAO90144.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Methyltransf_31 PF13847.1 GAO90146.1 - 8e-17 61.2 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90146.1 - 9.1e-16 58.4 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90146.1 - 1.3e-15 57.6 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90146.1 - 2.8e-13 49.8 0.0 3.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90146.1 - 6e-13 49.0 0.0 9.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90146.1 - 2.6e-12 47.0 0.0 3.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAO90146.1 - 2.9e-10 39.7 0.1 3.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAO90146.1 - 1.3e-09 37.6 0.1 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAO90146.1 - 1.9e-09 36.9 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO90146.1 - 2e-08 34.2 0.0 3.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAO90146.1 - 3e-06 26.1 0.0 4.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 GAO90146.1 - 3.7e-06 26.4 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 GAO90146.1 - 1.8e-05 23.8 0.0 2.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.11 GAO90146.1 - 3.7e-05 22.7 0.0 0.0043 15.9 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme FtsJ PF01728.14 GAO90146.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 GAO90146.1 - 0.0027 16.8 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 GAO90146.1 - 0.0063 15.5 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 GAO90146.1 - 0.0068 15.6 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 GAO90146.1 - 0.0074 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NNMT_PNMT_TEMT PF01234.12 GAO90146.1 - 0.0096 14.9 0.0 2.6 6.9 0.0 2.1 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 GAO90146.1 - 0.014 14.8 0.1 0.029 13.8 0.1 1.4 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.7 GAO90146.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.1 GAO90146.1 - 0.035 13.7 0.1 0.042 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 GAO90146.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltrans_SAM PF10672.4 GAO90146.1 - 0.098 11.4 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase CheR PF01739.13 GAO90146.1 - 0.14 11.4 0.0 2.7 7.2 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF43 PF01861.11 GAO90146.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF43 tRNA_U5-meth_tr PF05958.6 GAO90146.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Rieske PF00355.21 GAO90147.1 - 2.7e-10 39.6 0.0 5.5e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAO90147.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Aegerolysin PF06355.8 GAO90149.1 - 9.7e-45 151.6 1.3 1.1e-44 151.4 0.9 1.0 1 0 0 1 1 1 1 Aegerolysin Epimerase PF01370.16 GAO90151.1 - 1.4e-22 80.3 0.0 1.5e-21 76.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAO90151.1 - 3.3e-09 36.0 0.1 9.4e-06 24.7 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAO90151.1 - 2.2e-08 33.3 0.0 3.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAO90151.1 - 2.8e-08 32.9 0.7 1.1e-07 31.0 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein Epimerase_Csub PF13950.1 GAO90151.1 - 0.091 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 GAO90152.1 - 6.1e-05 22.5 0.0 0.00091 18.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO90152.1 - 0.0003 20.1 0.2 0.0043 16.3 0.0 2.6 1 1 1 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90152.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO90152.1 - 0.0047 15.8 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 GAO90152.1 - 0.0091 16.2 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAO90152.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PEP_mutase PF13714.1 GAO90153.1 - 1.3e-39 135.8 0.0 3.1e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Acyl-CoA_dh_1 PF00441.19 GAO90153.1 - 9.4e-16 58.2 1.1 1.4e-15 57.6 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ICL PF00463.16 GAO90153.1 - 8.1e-13 47.4 0.1 1.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Acyl-CoA_dh_M PF02770.14 GAO90153.1 - 5e-10 38.7 0.0 1.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAO90153.1 - 8.5e-09 35.9 0.1 3.1e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MoCo_carrier PF12694.2 GAO90153.1 - 0.14 11.6 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative molybdenum carrier Aldedh PF00171.17 GAO90154.1 - 3.6e-147 490.4 0.0 4.3e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family N2227 PF07942.7 GAO90154.1 - 0.17 10.8 0.1 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein Amidohydro_1 PF01979.15 GAO90155.1 - 9e-57 193.1 0.1 1.2e-56 192.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO90155.1 - 3e-15 57.0 0.3 1.2e-11 45.1 0.1 2.6 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 GAO90155.1 - 4.2e-15 55.8 0.2 1e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAO90155.1 - 1.7e-08 34.1 0.0 4.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 GAO90155.1 - 0.014 14.3 0.0 0.08 11.8 0.0 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase NmrA PF05368.8 GAO90156.1 - 5.3e-20 71.6 0.0 6.5e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90156.1 - 1.5e-09 38.1 0.0 2.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO90156.1 - 0.0022 17.4 0.0 0.0053 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO90156.1 - 0.0071 16.2 0.3 0.041 13.7 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 GAO90156.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAO90156.1 - 0.036 12.7 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GreA_GreB PF01272.14 GAO90156.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term KR PF08659.5 GAO90156.1 - 0.15 11.7 0.5 0.69 9.5 0.1 2.1 2 1 0 2 2 2 0 KR domain Glyco_hydro_88 PF07470.8 GAO90157.1 - 8.1e-85 284.8 4.9 1.1e-84 284.3 3.0 1.5 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 GAO90157.1 - 3.4 6.9 15.3 2.4 7.4 0.1 3.7 2 1 2 4 4 4 0 Glycosyl hydrolase family 76 MFS_1 PF07690.11 GAO90158.1 - 4.6e-33 114.4 23.8 4.6e-33 114.4 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3341 PF11821.3 GAO90158.1 - 0.024 14.0 1.6 0.071 12.5 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Form_Nir_trans PF01226.12 GAO90159.1 - 4.7e-76 254.9 19.0 5.4e-76 254.7 13.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.4 GAO90159.1 - 0.016 15.0 0.4 0.44 10.4 0.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) tRNA-synt_2b PF00587.20 GAO90161.1 - 0.016 14.7 0.1 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PHY PF00360.15 GAO90162.1 - 1.7e-29 102.2 0.0 3.3e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 GAO90162.1 - 7.7e-19 67.4 0.1 1.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO90162.1 - 4.6e-16 58.8 0.0 1.7e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 GAO90162.1 - 1.5e-15 57.6 0.0 1.7e-14 54.1 0.0 2.7 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 GAO90162.1 - 1.4e-11 44.1 0.1 5.1e-11 42.3 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 GAO90162.1 - 2.1e-08 34.6 0.0 6.9e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.1 GAO90162.1 - 0.071 12.8 0.0 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 GHKL domain DUF2296 PF10058.4 GAO90164.1 - 5.9e-21 73.9 0.1 1e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) bZIP_1 PF00170.16 GAO90165.1 - 9.6e-09 35.0 8.4 1.2e-07 31.6 5.9 2.1 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 GAO90165.1 - 0.023 14.5 0.2 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF1178 PF06676.6 GAO90165.1 - 0.029 14.5 1.7 0.39 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) bZIP_2 PF07716.10 GAO90165.1 - 0.041 13.7 15.6 0.05 13.4 4.2 2.7 2 1 1 3 3 3 0 Basic region leucine zipper DUF3972 PF13118.1 GAO90165.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Adeno_PIX PF03955.9 GAO90165.1 - 0.51 10.8 3.9 0.33 11.4 0.2 2.4 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) COesterase PF00135.23 GAO90166.1 - 1.3e-94 317.8 0.1 1.7e-85 287.7 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90166.1 - 3.4e-12 46.4 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO90166.1 - 0.0047 16.6 0.1 0.0077 15.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family 5_nucleotid_C PF02872.13 GAO90167.1 - 4.7e-33 114.3 0.0 6.9e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAO90167.1 - 1.6e-10 40.7 0.2 2.4e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Anoctamin PF04547.7 GAO90168.1 - 3.6e-126 421.4 3.9 4.6e-126 421.0 2.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_membrane PF00664.18 GAO90168.1 - 0.039 13.3 0.2 0.039 13.3 0.2 2.1 2 0 0 2 2 2 0 ABC transporter transmembrane region Acetyltransf_1 PF00583.19 GAO90169.1 - 2.6e-13 49.8 0.0 6.6e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GRIP PF01465.15 GAO90169.1 - 6.9e-11 41.4 0.6 1.6e-10 40.3 0.4 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 GAO90169.1 - 1.2e-09 37.8 60.6 0.0099 15.0 5.5 7.2 4 2 3 7 7 7 5 Reovirus sigma C capsid protein IncA PF04156.9 GAO90169.1 - 1.4e-09 37.8 171.5 4.5e-05 23.1 11.7 8.2 2 2 6 9 9 9 5 IncA protein DUF869 PF05911.6 GAO90169.1 - 5.7e-07 28.1 144.2 0.00029 19.2 38.7 5.3 1 1 4 5 5 5 3 Plant protein of unknown function (DUF869) FR47 PF08445.5 GAO90169.1 - 1.2e-06 28.1 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Filament PF00038.16 GAO90169.1 - 2.6e-06 27.1 146.2 5.9e-05 22.6 31.2 6.9 2 2 4 6 6 6 4 Intermediate filament protein Acetyltransf_7 PF13508.1 GAO90169.1 - 2.7e-05 24.2 0.0 7.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-F_leu_zip PF10473.4 GAO90169.1 - 3.1e-05 23.8 181.3 0.0031 17.3 6.5 10.0 3 2 6 9 9 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 GAO90169.1 - 0.0002 20.0 125.0 0.0069 14.9 18.5 6.0 2 2 3 5 5 5 3 AAA domain DUF4201 PF13870.1 GAO90169.1 - 0.00087 18.7 8.6 0.00087 18.7 6.0 10.2 2 2 8 10 10 10 5 Domain of unknown function (DUF4201) Spc7 PF08317.6 GAO90169.1 - 0.001 17.8 144.5 0.014 14.0 14.1 7.6 2 2 5 8 8 8 5 Spc7 kinetochore protein Acetyltransf_10 PF13673.1 GAO90169.1 - 0.0033 17.5 0.0 0.014 15.4 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PspA_IM30 PF04012.7 GAO90169.1 - 0.0055 16.1 22.0 0.0055 16.1 15.2 8.6 3 2 3 8 8 5 1 PspA/IM30 family GAS PF13851.1 GAO90169.1 - 0.021 14.0 158.6 0.079 12.1 10.5 10.3 2 2 7 10 10 9 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 GAO90169.1 - 0.64 7.6 181.1 0.14 9.8 28.6 4.6 2 2 2 4 4 4 0 Myosin tail APG6 PF04111.7 GAO90169.1 - 1.2 8.1 159.8 0.67 8.9 15.1 7.9 2 2 6 8 8 8 0 Autophagy protein Apg6 MscS_porin PF12795.2 GAO90169.1 - 2.1 7.5 148.2 0.074 12.3 21.1 7.7 2 2 3 6 6 5 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 GAO90169.1 - 6.7 6.5 188.7 0.041 13.7 16.0 8.8 2 2 5 8 8 8 0 Tropomyosin like cNMP_binding PF00027.24 GAO90170.1 - 8.5e-38 128.0 0.0 5.4e-20 71.0 0.0 5.0 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 GAO90170.1 - 3.6e-18 66.2 7.8 1.2e-17 64.4 3.6 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase MARVEL PF01284.18 GAO90171.1 - 2.4e-18 66.3 7.7 3e-18 66.0 5.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain MotA_ExbB PF01618.11 GAO90171.1 - 0.093 12.3 0.1 15 5.2 0.0 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family 7tm_4 PF13853.1 GAO90171.1 - 0.28 10.9 5.1 0.17 11.6 0.9 2.1 1 1 0 2 2 2 0 Olfactory receptor Fig1 PF12351.3 GAO90171.1 - 4.4 7.1 6.7 0.85 9.4 0.5 2.4 2 1 1 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 Actin PF00022.14 GAO90172.1 - 1.2e-53 181.9 0.0 9.4e-30 103.3 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 GAO90173.1 - 2.7e-29 100.8 6.7 2.9e-29 100.7 4.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 GAO90173.1 - 0.0087 15.7 2.8 0.011 15.4 2.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 YL1_C PF08265.6 GAO90174.1 - 8.2e-17 60.4 0.2 1.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain OmpA PF00691.15 GAO90174.1 - 0.055 13.8 0.2 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 OmpA family Got1 PF04178.7 GAO90175.1 - 3.3e-18 65.9 12.5 4.3e-18 65.5 8.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 GAO90175.1 - 0.022 14.4 2.8 0.022 14.4 1.9 1.8 2 0 0 2 2 2 0 YrhK-like protein TAT_signal PF10518.4 GAO90175.1 - 0.84 9.8 3.3 0.4 10.8 0.2 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Profilin PF00235.14 GAO90176.1 - 4.2e-32 110.7 0.2 4.6e-32 110.6 0.1 1.0 1 0 0 1 1 1 1 Profilin Lpp-LpqN PF10738.4 GAO90176.1 - 0.018 14.3 0.5 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Probable lipoprotein LpqN Sec63 PF02889.11 GAO90178.1 - 1.3e-148 494.3 0.0 4.9e-97 324.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAO90178.1 - 1.9e-53 180.3 0.3 2.2e-28 98.8 0.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO90178.1 - 1.1e-17 63.7 0.0 2.4e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAO90178.1 - 3.5e-15 56.2 0.0 7e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAO90178.1 - 8.9e-07 29.1 0.9 0.071 13.2 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 GAO90178.1 - 2.5e-05 23.9 0.1 0.023 14.4 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 GAO90178.1 - 0.00022 20.1 0.4 0.53 9.0 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 GAO90178.1 - 0.015 14.7 0.3 13 5.1 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Alba PF01918.16 GAO90178.1 - 0.056 13.0 0.0 7.5 6.2 0.0 2.8 2 0 0 2 2 2 0 Alba DUF3431 PF11913.3 GAO90179.1 - 9.2e-89 296.7 1.1 1.1e-88 296.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.17 GAO90180.1 - 4.6e-41 139.9 0.0 5.3e-40 136.4 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAO90180.1 - 9.1e-20 71.3 0.0 1.3e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO90180.1 - 1.7e-11 43.6 0.0 2.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 GAO90180.1 - 0.00036 20.6 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 GAO90180.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAO90180.1 - 0.0013 17.9 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 GAO90180.1 - 0.0019 18.2 0.0 0.026 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 GAO90180.1 - 0.0034 16.6 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAO90180.1 - 0.019 14.4 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 GAO90180.1 - 0.046 13.6 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAO90180.1 - 0.048 13.3 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 GAO90180.1 - 0.048 12.8 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 GAO90180.1 - 0.058 12.8 0.1 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 GAO90180.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO90180.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAO90180.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 GAO90180.1 - 0.14 12.1 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 GAO90181.1 - 1.3e-101 340.4 24.9 1.5e-101 340.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90181.1 - 7.9e-30 103.7 25.5 4.5e-18 65.0 4.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 GAO90181.1 - 0.0059 14.7 0.2 0.0059 14.7 0.1 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector FMN_dh PF01070.13 GAO90182.1 - 2.3e-122 408.2 0.1 2.9e-122 407.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAO90182.1 - 1e-24 86.1 0.0 2e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAO90182.1 - 2e-07 30.3 0.0 3.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAO90182.1 - 0.00029 19.8 0.1 0.00091 18.2 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAO90182.1 - 0.0014 17.8 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 GAO90182.1 - 0.0089 15.3 0.4 0.45 9.7 0.0 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 GAO90182.1 - 0.11 11.6 0.0 7.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos_2 PF12850.2 GAO90183.1 - 1e-06 28.6 0.1 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAO90183.1 - 0.00014 21.3 8.1 0.0015 17.9 0.9 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Pkinase PF00069.20 GAO90184.1 - 5.3e-41 140.4 1.3 1.8e-24 86.2 0.1 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90184.1 - 3.5e-14 52.4 0.2 3.1e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DNA_binding_1 PF01035.15 GAO90185.1 - 1.1e-22 79.5 0.0 1.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.4 GAO90186.1 - 1.8e-46 157.9 2.9 1.8e-46 157.9 2.0 2.7 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.1 GAO90186.1 - 0.16 12.0 1.8 0.29 11.1 1.3 1.4 1 0 0 1 1 1 0 SPATIAL Brr6_like_C_C PF10104.4 GAO90188.1 - 2.6e-42 143.5 0.4 3.4e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_transf_20 PF00982.16 GAO90189.1 - 4.2e-160 533.3 0.0 4.8e-160 533.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 GAO90189.1 - 0.00012 21.5 0.1 0.0011 18.4 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAO90189.1 - 0.0024 17.3 0.4 0.0085 15.6 0.1 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain DUF693 PF05113.8 GAO90189.1 - 0.0099 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF693) LVIVD PF08309.6 GAO90190.1 - 8.2e-09 34.3 0.1 0.052 12.5 0.1 4.8 5 0 0 5 5 5 3 LVIVD repeat Cutinase PF01083.17 GAO90191.1 - 1.5e-52 177.8 1.3 1.8e-52 177.6 0.9 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAO90191.1 - 0.0033 16.8 0.1 0.0057 16.1 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 GAO90191.1 - 0.0042 16.8 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) AA_permease PF00324.16 GAO90192.1 - 2.2e-132 441.7 39.9 2.5e-132 441.6 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAO90192.1 - 3.9e-33 114.6 47.2 5.3e-33 114.1 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease Ribonuclease PF00545.15 GAO90193.1 - 1.9e-20 72.7 0.2 2.6e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 ribonuclease Myticin-prepro PF10690.4 GAO90193.1 - 0.18 11.8 1.6 0.25 11.3 0.9 1.4 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel HsbA PF12296.3 GAO90194.1 - 7.5e-33 113.0 7.0 7.5e-33 113.0 4.8 2.9 2 1 1 3 3 3 1 Hydrophobic surface binding protein A NTR2 PF15458.1 GAO90195.1 - 0.013 14.7 0.3 0.099 11.8 0.0 2.3 2 1 1 3 3 3 0 Nineteen complex-related protein 2 Terpene_synth_C PF03936.11 GAO90196.1 - 0.024 13.8 0.0 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Methyltransf_31 PF13847.1 GAO90198.1 - 5.4e-27 94.2 0.0 7.6e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90198.1 - 2.2e-23 82.5 0.0 4.6e-23 81.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO90198.1 - 2.6e-16 59.4 0.0 3.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAO90198.1 - 4.4e-16 59.4 0.0 6.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90198.1 - 1.3e-15 57.6 0.1 5.2e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90198.1 - 3.3e-15 56.2 0.0 5.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90198.1 - 3.3e-14 52.9 0.0 5.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90198.1 - 3.7e-09 36.6 0.1 6.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAO90198.1 - 1.8e-08 33.9 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAO90198.1 - 8.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAO90198.1 - 7.9e-07 28.8 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 GAO90198.1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.12 GAO90198.1 - 0.0015 17.5 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 GAO90198.1 - 0.012 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.6 GAO90198.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 GAO90198.1 - 0.047 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 GAO90198.1 - 0.051 12.6 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 GAO90198.1 - 0.065 12.2 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WW PF00397.21 GAO90200.1 - 2.2e-05 24.2 0.4 6.9e-05 22.6 0.3 2.0 1 0 0 1 1 1 1 WW domain Na_Ca_ex PF01699.19 GAO90201.1 - 2.2e-36 124.5 32.4 1.7e-20 73.0 8.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Macro_2 PF14519.1 GAO90202.1 - 0.0022 17.1 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain Anoctamin PF04547.7 GAO90204.1 - 4.3e-105 351.9 5.6 5.4e-105 351.6 3.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel zf-C3HC4_4 PF15227.1 GAO90204.1 - 0.12 12.2 1.4 0.24 11.2 0.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EBP PF05241.7 GAO90204.1 - 0.16 10.9 5.7 0.31 10.0 0.0 2.8 3 0 0 3 3 3 0 Emopamil binding protein DUF1212 PF06738.7 GAO90205.1 - 2.1e-60 203.4 10.6 6.5e-55 185.6 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAO90205.1 - 3.3e-27 94.9 9.0 3.3e-27 94.9 6.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Pectate_lyase_3 PF12708.2 GAO90206.1 - 2.7e-48 165.0 24.3 5.4e-39 134.6 6.4 3.4 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAO90206.1 - 0.00072 18.9 0.9 0.039 13.4 0.0 3.1 3 0 0 3 3 3 1 N terminal extension of bacteriophage endosialidase DUF883 PF05957.8 GAO90207.1 - 0.23 11.8 4.8 1.8 9.0 0.5 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TALPID3 PF15324.1 GAO90207.1 - 0.27 8.5 4.9 0.32 8.2 3.4 1.2 1 0 0 1 1 1 0 Hedgehog signalling target AA_permease_2 PF13520.1 GAO90208.1 - 6.4e-61 206.1 47.6 8e-61 205.8 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO90208.1 - 1.4e-10 40.1 39.4 2.7e-10 39.2 27.3 1.4 1 1 0 1 1 1 1 Amino acid permease MIP PF00230.15 GAO90209.1 - 4.8e-46 157.0 7.4 6.2e-46 156.6 5.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.16 GAO90210.1 - 2e-14 54.0 0.0 4.9e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAO90210.1 - 6.5e-09 35.8 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 GAO90210.1 - 5.1e-08 33.2 0.0 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 GAO90210.1 - 1.8e-05 24.7 0.0 0.00019 21.3 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 GAO90210.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Protoglobin CamS PF07537.6 GAO90210.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Ribonuc_L-PSP PF01042.16 GAO90211.1 - 1.5e-20 73.1 0.0 3.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 GAO90211.1 - 7.6e-17 61.0 0.1 9.3e-16 57.4 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90211.1 - 1.1e-09 38.0 13.1 2e-09 37.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LOH1CR12 PF10158.4 GAO90212.1 - 0.016 14.9 0.3 0.046 13.5 0.1 1.7 1 1 0 1 1 1 0 Tumour suppressor protein DUF3716 PF12511.3 GAO90213.1 - 0.00024 20.6 2.6 0.00024 20.6 1.8 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3716) NmrA PF05368.8 GAO90216.1 - 9e-19 67.6 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90216.1 - 6.1e-10 39.3 0.0 8.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAO90216.1 - 0.00013 21.9 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 GAO90216.1 - 0.0032 17.4 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 GAO90216.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HLH PF00010.21 GAO90217.1 - 5.1e-11 42.1 0.3 1.8e-10 40.3 0.1 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 GAO90217.1 - 0.04 13.8 0.3 0.069 13.1 0.2 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4407 PF14362.1 GAO90217.1 - 0.076 11.9 1.9 0.092 11.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HpaP PF09483.5 GAO90217.1 - 0.14 12.1 9.0 0.2 11.5 6.3 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Tannase PF07519.6 GAO90218.1 - 2.8e-143 478.0 4.1 3.5e-143 477.7 2.8 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Planc_extracel PF07595.7 GAO90219.1 - 0.071 12.8 1.2 0.071 12.8 0.8 2.5 4 0 0 4 4 4 0 Planctomycete extracellular ATP-synt_E PF05680.7 GAO90219.1 - 0.08 12.8 1.2 0.088 12.7 0.8 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF4404 PF14357.1 GAO90219.1 - 0.47 10.9 3.5 0.55 10.6 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3602 PF12223.3 GAO90219.1 - 0.54 10.6 3.5 0.5 10.7 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) Pro-kuma_activ PF09286.6 GAO90220.1 - 2.2e-37 128.2 0.1 1.6e-36 125.5 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAO90220.1 - 6.8e-12 45.1 0.1 2.4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Subtilase family Imm29 PF15575.1 GAO90220.1 - 0.03 13.9 0.6 0.63 9.6 0.0 2.4 3 0 0 3 3 3 0 Immunity protein 29 SKG6 PF08693.5 GAO90221.1 - 0.047 13.0 2.5 0.17 11.2 1.7 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Hamartin PF04388.7 GAO90221.1 - 0.059 12.0 1.8 0.059 12.0 1.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.8 GAO90221.1 - 5.2 6.1 6.4 6.7 5.8 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AA_permease_2 PF13520.1 GAO90222.1 - 1.7e-56 191.5 44.1 2.2e-56 191.2 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO90222.1 - 1.5e-21 76.3 36.1 1.9e-21 75.9 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.8 GAO90222.1 - 2.6 7.2 7.5 0.17 11.0 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) NmrA PF05368.8 GAO90223.1 - 1.2e-36 126.1 0.0 2e-36 125.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90223.1 - 5.6e-08 33.0 0.2 1.3e-07 31.7 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAO90223.1 - 4.6e-06 26.2 0.0 7.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAO90223.1 - 1.3e-05 25.1 0.4 3.8e-05 23.6 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAO90223.1 - 0.00026 19.7 0.0 0.00054 18.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAO90223.1 - 0.0069 16.0 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 GAO90223.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3425 PF11905.3 GAO90224.1 - 7.5e-15 55.0 2.3 3.8e-14 52.7 1.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAO90224.1 - 1 9.3 7.7 1.9 8.5 5.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor CRPA PF05745.6 GAO90225.1 - 0.056 13.2 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) JTB PF05439.7 GAO90226.1 - 0.38 10.5 0.0 0.38 10.5 0.0 1.9 3 0 0 3 3 3 0 Jumping translocation breakpoint protein (JTB) RimM PF01782.13 GAO90227.1 - 0.085 12.7 0.0 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 RimM N-terminal domain Esterase_phd PF10503.4 GAO90228.1 - 1.2e-10 41.0 9.9 3.3e-06 26.5 0.8 3.0 2 1 0 2 2 2 2 Esterase PHB depolymerase CBM_1 PF00734.13 GAO90228.1 - 9e-10 38.0 9.9 9e-10 38.0 6.9 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 GAO90228.1 - 4.8e-07 29.2 0.2 9.8e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family His_Phos_1 PF00300.17 GAO90230.1 - 2.1e-25 89.6 0.0 3.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Melibiase PF02065.13 GAO90230.1 - 3e-11 42.6 0.0 3.4e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 Melibiase MFS_1 PF07690.11 GAO90231.1 - 8.4e-23 80.6 56.5 2e-14 53.0 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 GAO90231.1 - 0.00041 19.1 0.7 0.00041 19.1 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) zf-LITAF-like PF10601.4 GAO90231.1 - 0.51 10.2 1.8 24 4.8 0.1 2.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF1228 PF06779.9 GAO90231.1 - 2.2 8.3 15.0 0.32 11.0 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) CPG4 PF15481.1 GAO90232.1 - 0.12 12.7 1.8 0.13 12.5 0.5 1.5 1 1 0 1 1 1 0 Chondroitin proteoglycan 4 HET PF06985.6 GAO90233.1 - 3.8e-23 82.1 0.0 8.5e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.19 GAO90234.1 - 6.5e-06 26.0 0.3 1.4e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAO90234.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAO90234.1 - 0.002 17.7 0.3 0.004 16.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO90234.1 - 0.0044 17.1 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAO90234.1 - 0.013 15.3 0.1 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pho86 PF11124.3 GAO90234.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Sugar_tr PF00083.19 GAO90235.1 - 9.1e-47 159.6 16.9 4.8e-46 157.2 11.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90235.1 - 4.6e-21 74.9 37.9 2.9e-19 68.9 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Con-6 PF10346.4 GAO90236.1 - 2.8e-37 125.7 4.9 1.3e-21 75.7 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 GAO90236.1 - 0.00055 19.4 1.7 0.36 10.2 0.1 2.1 1 1 1 2 2 2 2 SpoIIIAH-like protein Toxin_52 PF15605.1 GAO90236.1 - 0.0006 19.6 1.1 0.27 11.1 0.1 2.1 1 1 1 2 2 2 2 Putative toxin 52 PASTA PF03793.14 GAO90236.1 - 0.063 12.9 0.1 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 PASTA domain DUF3533 PF12051.3 GAO90237.1 - 5.2e-137 456.6 8.9 5.9e-137 456.4 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Sterol_MT_C PF08498.5 GAO90238.1 - 4.9e-29 100.0 0.1 7.6e-29 99.4 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 GAO90238.1 - 4e-22 78.5 0.0 7.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90238.1 - 4e-18 65.4 0.0 5.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90238.1 - 3.7e-14 52.8 0.0 7.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO90238.1 - 3.1e-13 49.3 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAO90238.1 - 6.7e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAO90238.1 - 7.3e-13 48.2 0.0 9.7e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 GAO90238.1 - 3.7e-11 43.5 0.0 8.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90238.1 - 2.7e-10 40.5 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90238.1 - 1.4e-09 38.0 0.0 3.7e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAO90238.1 - 6.5e-06 25.8 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAO90238.1 - 7.2e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 GAO90238.1 - 0.00021 19.7 0.0 0.00029 19.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.5 GAO90238.1 - 0.0005 19.6 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 GAO90238.1 - 0.00088 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 GAO90238.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 GAO90238.1 - 0.0018 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 GAO90238.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 GAO90238.1 - 0.027 13.6 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 GAO90238.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 GAO90238.1 - 0.041 14.7 0.0 0.14 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 GAO90238.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RRM_5 PF13893.1 GAO90239.1 - 8.3e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAO90239.1 - 1.8e-09 37.0 0.0 3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90239.1 - 2.6e-05 24.1 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO90239.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 GAO90240.1 - 2.8e-05 23.8 1.7 4e-05 23.3 1.2 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAO90240.1 - 8e-05 22.7 1.0 0.00015 21.9 0.7 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 GAO90241.1 - 7.5e-19 67.2 0.6 7.5e-19 67.2 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain Fungal_trans_2 PF11951.3 GAO90242.1 - 9.3e-36 123.2 4.0 1.3e-35 122.7 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphoesterase PF04185.9 GAO90242.1 - 3e-33 115.5 3.2 5.9e-33 114.5 2.2 1.5 1 0 0 1 1 1 1 Phosphoesterase family Zn_clus PF00172.13 GAO90242.1 - 1e-07 31.7 11.6 1.9e-07 30.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAO90243.1 - 4.3e-27 95.0 1.6 6.2e-27 94.5 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90243.1 - 3.2e-16 59.8 0.0 3.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO90243.1 - 1.6e-09 37.6 1.3 2.3e-09 37.1 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAO90243.1 - 0.0017 18.0 0.3 0.0033 17.1 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAO90243.1 - 0.0046 16.9 0.9 0.014 15.3 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO90243.1 - 0.0063 15.9 0.2 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAO90243.1 - 0.02 13.9 0.1 0.053 12.6 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pellino PF04710.9 GAO90243.1 - 0.073 11.7 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Pellino 3Beta_HSD PF01073.14 GAO90243.1 - 0.14 10.8 0.2 1.3 7.6 0.2 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 GAO90243.1 - 0.67 9.7 3.4 1.8 8.4 0.5 2.6 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldedh PF00171.17 GAO90244.1 - 9.4e-130 433.0 0.0 1e-129 432.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO90244.1 - 0.00099 17.9 0.0 0.0041 15.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) GATase PF00117.23 GAO90245.1 - 1.8e-14 53.6 0.0 2.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAO90245.1 - 0.0036 16.7 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 GAO90245.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Gln-synt_C PF00120.19 GAO90246.1 - 7.6e-57 192.4 0.0 1.1e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain D-ser_dehydrat PF14031.1 GAO90246.1 - 8.9e-26 89.9 1.0 2.2e-25 88.6 0.7 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAO90246.1 - 1.2e-15 57.6 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SnoaL PF07366.7 GAO90247.1 - 0.0019 17.7 0.0 0.0045 16.5 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAO90247.1 - 0.0052 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.13 GAO90247.1 - 0.097 11.9 0.0 0.86 8.8 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.11 GAO90248.1 - 1.7e-16 59.8 5.9 1.7e-16 59.8 4.1 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90248.1 - 1.4e-07 30.4 9.3 6.9e-07 28.1 5.4 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90249.1 - 6e-37 127.1 33.7 6e-37 127.1 23.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GDC-P PF02347.11 GAO90251.1 - 2.2e-177 590.0 0.1 6.3e-164 545.7 0.0 2.6 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 GAO90251.1 - 3.2e-07 29.7 0.2 6.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAO90251.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Amidohydro_1 PF01979.15 GAO90252.1 - 3.5e-29 102.5 0.0 4.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAO90252.1 - 0.0021 17.3 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO90252.1 - 0.02 14.9 0.5 0.061 13.3 0.1 1.9 2 1 0 2 2 2 0 Amidohydrolase RhgB_N PF09284.5 GAO90253.1 - 6.6e-121 402.3 6.2 6.6e-121 402.3 4.3 1.6 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 GAO90253.1 - 1.2e-59 200.7 0.2 6.7e-59 198.2 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 GAO90253.1 - 5.9e-19 67.9 4.1 1.9e-18 66.3 2.8 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 GAO90253.1 - 2.8e-06 27.3 1.4 2.8e-06 27.3 1.0 4.2 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.2 GAO90253.1 - 0.00054 19.5 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3823) DUF2012 PF09430.5 GAO90253.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) DUF4480 PF13715.1 GAO90253.1 - 0.12 12.4 1.1 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) Peptidase_S28 PF05577.7 GAO90254.1 - 2.2e-58 197.8 0.9 8.9e-58 195.8 0.5 1.9 2 1 0 2 2 2 1 Serine carboxypeptidase S28 p450 PF00067.17 GAO90255.1 - 1e-61 208.9 0.0 1.3e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RSN1_TM PF13967.1 GAO90255.1 - 0.16 11.5 0.2 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Med27 PF11571.3 GAO90256.1 - 7.3e-22 77.3 0.0 1.3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 Phage_prot_Gp6 PF05133.9 GAO90256.1 - 0.28 9.7 2.7 0.33 9.4 1.7 1.3 1 1 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like DUF4614 PF15391.1 GAO90257.1 - 0.78 9.4 11.7 1.5 8.5 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SNF2_N PF00176.18 GAO90259.1 - 9.4e-72 241.3 0.0 1.8e-71 240.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAO90259.1 - 6.2e-15 54.8 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain V_ATPase_I PF01496.14 GAO90259.1 - 2.2 6.0 4.3 4 5.1 3.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 GAO90260.1 - 4.8e-51 173.4 0.0 1.2e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90260.1 - 8.7e-23 80.7 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO90260.1 - 0.00042 20.1 0.1 0.0009 19.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAO90260.1 - 0.0022 17.4 1.0 0.012 14.9 0.7 2.0 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 GAO90260.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) eIF-3c_N PF05470.7 GAO90261.1 - 4.6e-176 586.4 22.9 2.1e-140 468.6 0.4 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 GAO90261.1 - 1.7e-12 47.5 1.6 1.6e-11 44.4 0.0 3.0 3 0 0 3 3 3 1 PCI domain DUF357 PF04010.8 GAO90261.1 - 0.033 13.8 0.5 0.17 11.6 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF357) EAP30 PF04157.11 GAO90262.1 - 1.2e-58 197.8 0.0 1.5e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 GAO90262.1 - 0.001 18.6 0.1 0.007 16.0 0.0 2.3 3 0 0 3 3 3 1 MarR family Ftsk_gamma PF09397.5 GAO90262.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ftsk gamma domain Ribosomal_L30_N PF08079.7 GAO90263.1 - 8.8e-25 86.5 18.8 1.6e-24 85.6 13.0 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 GAO90263.1 - 9.6e-16 57.1 2.9 1.3e-15 56.6 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol3_a_NII PF11490.3 GAO90263.1 - 1.7 8.2 7.8 18 4.9 3.8 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II PRK PF00485.13 GAO90264.1 - 0.00081 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 GAO90264.1 - 0.053 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 GAO90264.1 - 0.082 12.8 0.1 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 GAO90264.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain adh_short PF00106.20 GAO90265.1 - 1.8e-60 203.6 8.5 6.9e-30 104.1 2.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 GAO90265.1 - 8.1e-31 105.9 0.0 1.5e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 GAO90265.1 - 9.1e-29 100.3 2.8 5.7e-14 52.1 0.4 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 GAO90265.1 - 7.3e-05 21.8 3.3 0.0013 17.8 0.4 2.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 GAO90265.1 - 0.0016 17.9 1.3 0.95 8.8 0.1 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAO90265.1 - 1.8 8.1 4.9 0.93 9.1 0.9 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBR PF01485.16 GAO90266.1 - 6.1e-06 26.0 3.0 6.1e-06 26.0 2.1 4.5 4 1 0 4 4 4 2 IBR domain FbpA PF05833.6 GAO90266.1 - 0.072 11.6 1.4 0.11 11.0 0.1 1.8 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) DMA PF03474.9 GAO90266.1 - 0.074 12.9 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif MFS_1 PF07690.11 GAO90267.1 - 7.5e-42 143.2 46.1 5.1e-40 137.2 31.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90267.1 - 9.2e-13 47.5 12.2 9.2e-13 47.5 8.5 3.2 2 1 2 4 4 4 1 Sugar (and other) transporter PALP PF00291.20 GAO90268.1 - 4.9e-28 98.2 0.0 2.5e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 GAO90268.1 - 3.7e-10 40.1 0.0 8.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain NAF PF03822.9 GAO90268.1 - 0.076 12.7 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 NAF domain Ferric_reduct PF01794.14 GAO90269.1 - 2e-17 63.4 15.1 1e-16 61.1 8.9 2.7 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAO90269.1 - 1.6e-15 56.8 0.0 3.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAO90269.1 - 1.2e-11 44.7 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 GAO90269.1 - 0.0025 17.8 8.6 0.13 12.4 2.3 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) zf-4CXXC_R1 PF10497.4 GAO90270.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Cys_Met_Meta_PP PF01053.15 GAO90271.1 - 3.8e-142 473.1 0.0 4.5e-142 472.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAO90271.1 - 1.3e-05 24.1 0.0 2.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAO90271.1 - 4.1e-05 22.6 0.0 6.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO90271.1 - 0.00036 19.6 0.0 0.00092 18.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 GAO90271.1 - 0.00044 18.6 0.0 0.0025 16.2 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 GAO90271.1 - 0.00098 18.3 0.0 0.0027 16.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 GAO90272.1 - 7.6e-33 113.4 0.0 7.6e-32 110.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90272.1 - 0.00073 19.3 0.9 0.0014 18.5 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.9 GAO90273.1 - 5.8e-175 582.2 33.0 5.8e-175 582.2 22.9 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 GAO90273.1 - 1.3e-10 41.1 0.4 3.9e-09 36.3 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAO90273.1 - 1.5e-08 34.2 0.1 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase FlgM PF04316.8 GAO90273.1 - 0.15 11.9 0.1 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Csm1 PF12539.3 GAO90274.1 - 3.3e-27 94.7 1.8 1.6e-26 92.6 0.2 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF2968 PF11180.3 GAO90274.1 - 0.00069 19.0 14.0 0.00069 19.0 9.7 2.4 3 0 0 3 3 2 1 Protein of unknown function (DUF2968) Vps5 PF09325.5 GAO90274.1 - 0.00074 18.8 5.7 0.0023 17.2 3.9 1.9 1 0 0 1 1 1 1 Vps5 C terminal like MscS_porin PF12795.2 GAO90274.1 - 0.0009 18.6 25.9 0.0034 16.7 18.0 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 GAO90274.1 - 0.001 17.6 9.7 0.001 17.6 6.7 1.5 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.6 GAO90274.1 - 0.0026 16.4 9.7 0.0053 15.4 6.7 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein USP8_interact PF08941.5 GAO90274.1 - 0.0038 16.5 2.2 0.005 16.1 0.8 1.7 1 1 0 1 1 1 1 USP8 interacting APG6 PF04111.7 GAO90274.1 - 0.0039 16.2 13.2 0.0087 15.1 9.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 Cluap1 PF10234.4 GAO90274.1 - 0.0053 16.0 9.6 0.0097 15.1 6.7 1.4 1 0 0 1 1 1 1 Clusterin-associated protein-1 Cauli_DNA-bind PF03310.8 GAO90274.1 - 0.0089 15.8 1.1 0.022 14.5 0.7 1.7 1 0 0 1 1 1 1 Caulimovirus DNA-binding protein CENP-K PF11802.3 GAO90274.1 - 0.012 14.8 5.3 0.019 14.1 3.7 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Matrilin_ccoil PF10393.4 GAO90274.1 - 0.022 14.1 1.2 5.9 6.3 0.2 2.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 GAO90274.1 - 0.051 12.7 7.0 0.38 9.8 3.5 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 GAO90274.1 - 0.062 12.4 17.0 0.051 12.7 9.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 GAO90274.1 - 0.068 13.3 7.9 0.078 13.0 3.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AT_hook PF02178.14 GAO90274.1 - 0.093 12.4 14.1 0.41 10.4 2.4 3.7 2 0 0 2 2 2 0 AT hook motif Phage_GP20 PF06810.6 GAO90274.1 - 0.11 11.9 10.3 0.14 11.5 6.2 2.0 2 0 0 2 2 1 0 Phage minor structural protein GP20 DUF1664 PF07889.7 GAO90274.1 - 0.13 12.0 6.2 0.26 11.0 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3837 PF12939.2 GAO90274.1 - 0.2 11.7 3.7 0.25 11.3 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) Atg14 PF10186.4 GAO90274.1 - 0.22 10.4 9.1 0.47 9.3 6.3 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 GAO90274.1 - 0.24 11.2 10.6 0.55 10.0 7.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.19 GAO90274.1 - 0.29 10.8 2.4 0.64 9.7 1.6 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ADIP PF11559.3 GAO90274.1 - 0.43 10.4 21.4 0.091 12.6 11.9 2.2 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 GAO90274.1 - 0.55 10.6 12.4 0.9 9.9 5.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 GAO90274.1 - 0.83 7.4 3.3 1.6 6.5 2.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 GAO90274.1 - 1.3 8.9 24.4 0.11 12.3 7.2 3.9 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Dzip-like_N PF13815.1 GAO90274.1 - 1.9 8.3 8.5 7 6.4 4.9 2.7 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal NPV_P10 PF05531.7 GAO90274.1 - 2.3 8.5 6.5 19 5.6 2.9 3.0 1 1 2 3 3 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 GAO90274.1 - 2.4 8.0 8.0 12 5.7 5.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bap31 PF05529.7 GAO90274.1 - 6.4 6.1 15.9 1.5 8.2 5.3 2.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like IncA PF04156.9 GAO90274.1 - 6.7 6.2 24.4 0.067 12.7 8.8 2.9 2 1 1 4 4 3 0 IncA protein AAA PF00004.24 GAO90275.1 - 4e-38 130.5 0.0 1.2e-37 129.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAO90275.1 - 7.4e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO90275.1 - 1.8e-05 24.8 0.3 0.00056 20.0 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAO90275.1 - 2e-05 25.4 0.4 7.8e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAO90275.1 - 3.2e-05 24.0 0.2 0.00035 20.6 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAO90275.1 - 3.7e-05 22.8 0.0 6.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAO90275.1 - 3.8e-05 23.4 0.1 0.00035 20.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAO90275.1 - 9.2e-05 21.9 0.0 0.00033 20.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 GAO90275.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAO90275.1 - 0.0003 20.6 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAO90275.1 - 0.0004 19.8 0.1 0.037 13.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 GAO90275.1 - 0.0006 19.8 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAO90275.1 - 0.00092 18.4 0.1 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAO90275.1 - 0.0011 19.1 0.0 0.0034 17.5 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 GAO90275.1 - 0.0027 17.7 0.2 0.0073 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 GAO90275.1 - 0.0033 17.1 0.4 0.01 15.4 0.0 2.1 2 0 0 2 2 1 1 NACHT domain AAA_19 PF13245.1 GAO90275.1 - 0.0047 16.6 0.1 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 GAO90275.1 - 0.0055 15.8 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 GAO90275.1 - 0.0056 16.9 0.1 0.017 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 GAO90275.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAO90275.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 GAO90275.1 - 0.017 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 GAO90275.1 - 0.022 15.0 0.0 0.058 13.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 GAO90275.1 - 0.044 12.7 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 GAO90275.1 - 0.051 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 GAO90275.1 - 0.059 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 GAO90275.1 - 0.083 12.5 0.0 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase SKI PF01202.17 GAO90275.1 - 0.086 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 GAO90275.1 - 0.096 11.5 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 GAO90275.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 GAO90275.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 GAO90275.1 - 0.11 11.5 0.0 0.63 9.1 0.0 2.0 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 GAO90275.1 - 0.16 10.6 0.0 0.3 9.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus LysM PF01476.15 GAO90276.1 - 0.026 14.4 0.0 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 LysM domain COesterase PF00135.23 GAO90277.1 - 6.3e-90 302.4 0.0 7.1e-89 298.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAO90277.1 - 0.00012 21.3 0.1 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAO90277.1 - 0.00022 20.8 0.8 0.0016 18.0 0.0 2.4 2 1 0 3 3 3 1 alpha/beta hydrolase fold FKBP_C PF00254.23 GAO90278.1 - 1.2e-24 86.1 0.0 1.4e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 GAO90279.1 - 1.9e-11 44.0 0.0 4.5e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 PHP domain ACPS PF01648.15 GAO90280.1 - 1.9e-18 66.3 0.0 2.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2611 PF11022.3 GAO90281.1 - 1e-33 115.2 0.2 1.2e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 GAO90282.1 - 1.7e-69 232.4 0.1 2.5e-69 231.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Ribonuc_L-PSP PF01042.16 GAO90284.1 - 4.2e-39 133.0 0.0 4.6e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP EAP30 PF04157.11 GAO90287.1 - 1.8e-53 180.9 0.1 2.4e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 GAO90287.1 - 1.2e-25 89.1 0.0 1.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 GAO90287.1 - 0.0011 18.4 1.0 0.0011 18.4 0.7 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 GAO90287.1 - 0.0016 17.5 8.2 0.0078 15.2 0.2 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 GAO90287.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 GAO90287.1 - 1.3 8.8 4.8 0.72 9.7 0.1 2.3 1 1 2 3 3 3 0 Double zinc ribbon Rubredoxin PF00301.15 GAO90287.1 - 4.3 7.2 6.7 0.86 9.5 0.2 3.0 4 0 0 4 4 4 0 Rubredoxin SAC3_GANP PF03399.11 GAO90288.1 - 5.1e-70 235.1 0.1 8.2e-70 234.5 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SH3_1 PF00018.23 GAO90288.1 - 1.1e-24 85.5 0.0 4.6e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 GAO90288.1 - 6.2e-15 54.5 0.1 6.3e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 GAO90288.1 - 1e-12 47.8 0.0 2.8e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 GAO90288.1 - 2.6e-09 36.3 0.0 1.7e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 GAO90288.1 - 5.7e-09 35.5 0.2 1.2e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 PB1 domain PCI_Csn8 PF10075.4 GAO90288.1 - 0.00045 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 AFG1_ATPase PF03969.11 GAO90289.1 - 3.8e-98 328.6 0.0 1.5e-92 310.2 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 GAO90289.1 - 0.00032 20.7 0.5 0.31 10.9 0.0 3.0 3 1 1 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.13 GAO90289.1 - 0.0012 18.5 0.2 0.051 13.2 0.0 2.3 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 GAO90289.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAO90289.1 - 0.0036 17.4 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAO90289.1 - 0.01 16.0 0.0 0.038 14.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 GAO90289.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAO90289.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4246 PF14033.1 GAO90290.1 - 6.4e-194 645.2 3.6 8.7e-194 644.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 GAO90290.1 - 0.0003 21.0 0.0 0.0077 16.4 0.0 2.4 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase CHASE4 PF05228.8 GAO90290.1 - 0.04 13.4 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 CHASE4 domain Amidase PF01425.16 GAO90291.1 - 1.5e-100 337.1 0.0 1.7e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Chitin_synth_1 PF01644.12 GAO90292.1 - 3.3e-86 287.1 0.1 5.2e-86 286.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAO90292.1 - 6.1e-34 115.5 0.3 1.9e-33 113.9 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAO90292.1 - 1.1e-21 76.8 0.5 6.4e-20 71.0 0.0 2.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAO90292.1 - 7.6e-08 32.2 0.4 2.6e-07 30.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAO90292.1 - 1e-05 25.4 0.0 2.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1774 PF08611.5 GAO90293.1 - 3.1e-39 133.0 0.7 3.1e-39 133.0 0.5 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) TMEM191C PF15194.1 GAO90293.1 - 0.94 9.3 3.2 12 5.7 0.0 2.8 2 1 1 3 3 3 0 TMEM191C family Inositol_P PF00459.20 GAO90294.1 - 1.6e-36 125.9 0.2 3.4e-36 124.9 0.2 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.12 GAO90295.1 - 3.8e-26 91.9 1.3 5.6e-26 91.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAO90295.1 - 1.9e-06 27.5 0.1 3.7e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 GAO90296.1 - 5.3e-25 87.8 7.2 2.3e-24 85.8 5.0 2.0 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 GAO90296.1 - 0.0031 17.1 0.3 0.0079 15.8 0.1 1.9 2 0 0 2 2 2 1 R3H domain MFS_1 PF07690.11 GAO90298.1 - 2e-27 95.8 26.1 2.5e-27 95.5 18.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TGT PF01702.13 GAO90299.1 - 1.7e-92 309.0 0.0 2.1e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 GAO90300.1 - 1.1e-112 375.4 0.0 1.3e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.11 GAO90301.1 - 4.2e-24 84.1 21.5 7.5e-13 48.1 5.9 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 GAO90301.1 - 0.01 15.6 3.8 0.01 15.6 2.6 2.6 2 1 0 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 GAO90301.1 - 0.074 13.2 13.2 0.71 10.1 3.0 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.1 GAO90301.1 - 1.2 8.8 5.0 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAO90301.1 - 1.2 8.7 4.8 1.4 8.5 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Hist_deacetyl PF00850.14 GAO90302.1 - 8.7e-64 215.7 0.1 1.5e-63 214.9 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DUF1096 PF06493.6 GAO90303.1 - 1.2 9.1 7.9 5 7.1 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) Ala_racemase_N PF01168.15 GAO90304.1 - 3.6e-43 147.6 0.0 4.1e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 GAO90305.1 - 3.8e-125 418.1 6.5 4.5e-125 417.9 4.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 GAO90305.1 - 4e-46 155.6 0.0 9.9e-46 154.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 GAO90305.1 - 2.6e-20 72.8 0.0 6.7e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF1096 PF06493.6 GAO90306.1 - 5 7.1 41.7 1.9 8.4 11.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1096) Homeobox PF00046.24 GAO90307.1 - 1e-16 60.2 3.9 2.1e-16 59.2 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAO90307.1 - 0.029 14.0 0.2 0.08 12.6 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.8 GAO90307.1 - 0.64 9.5 4.2 0.95 9.0 2.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region efThoc1 PF11957.3 GAO90308.1 - 2.5e-182 606.7 2.7 3.2e-182 606.4 1.9 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 GAO90309.1 - 2e-24 86.0 0.0 3.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAO90309.1 - 2.8e-23 82.7 0.0 5.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO90309.1 - 6.3e-10 38.6 0.1 4.6e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAO90309.1 - 1.2e-05 25.0 0.0 0.002 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 GAO90309.1 - 1.4e-05 25.0 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAO90309.1 - 0.00012 21.7 0.0 0.039 13.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 GAO90309.1 - 0.0016 18.5 0.1 0.013 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 GAO90309.1 - 0.0017 17.7 0.0 0.0047 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 GAO90309.1 - 0.0023 16.8 0.0 0.25 10.1 0.0 2.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DEAD PF00270.24 GAO90309.1 - 0.0025 17.3 0.1 0.035 13.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA PF00004.24 GAO90309.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAO90309.1 - 0.004 17.9 0.0 0.28 11.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAO90309.1 - 0.0065 16.4 0.0 0.045 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 GAO90309.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 GAO90309.1 - 0.022 13.8 0.0 0.061 12.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 GAO90309.1 - 0.051 12.4 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 GAO90309.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 GAO90309.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase UvrD-helicase PF00580.16 GAO90309.1 - 0.083 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_14 PF13173.1 GAO90309.1 - 0.12 12.2 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAO90309.1 - 0.21 11.7 0.0 0.55 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 GAO90309.1 - 0.31 9.8 0.0 0.5 9.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 GAO90309.1 - 0.33 9.8 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase 4HBT PF03061.17 GAO90310.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Tfb2 PF03849.9 GAO90311.1 - 1.1e-143 478.3 0.0 2.2e-143 477.3 0.0 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 GAO90311.1 - 7.6e-06 25.7 0.0 5.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1654 PF07867.6 GAO90311.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) PhzC-PhzF PF02567.11 GAO90313.1 - 9.4e-48 162.8 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 GAO90314.1 - 9.3e-96 320.1 0.0 9.3e-96 320.1 0.0 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 GAO90314.1 - 9.5e-72 242.7 41.1 1e-67 229.3 5.1 4.1 2 1 0 3 3 3 2 Timeless protein C terminal region 3HCDH_N PF02737.13 GAO90315.1 - 4.6e-52 176.2 1.2 6.3e-52 175.8 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAO90315.1 - 7e-34 116.1 0.0 1.7e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAO90315.1 - 6.5e-05 22.8 0.4 0.00023 21.0 0.3 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAO90315.1 - 0.01 15.5 0.9 0.02 14.6 0.6 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 GAO90315.1 - 0.014 14.2 0.1 0.014 14.2 0.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAO90315.1 - 0.022 13.9 0.1 0.051 12.7 0.0 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAHP_synth_1 PF00793.15 GAO90315.1 - 0.031 12.9 0.1 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 DAHP synthetase I family TrkA_N PF02254.13 GAO90315.1 - 0.085 12.8 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.12 GAO90315.1 - 0.085 13.2 2.2 0.65 10.4 1.5 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 GAO90315.1 - 0.1 12.6 0.4 0.31 11.0 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO90315.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.14 GAO90316.1 - 2.5e-119 398.2 0.0 2.9e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Actin GCIP PF13324.1 GAO90317.1 - 1.4e-09 37.6 1.0 1.4e-08 34.3 0.0 2.1 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting PEX11 PF05648.9 GAO90317.1 - 0.066 12.4 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4611 PF15387.1 GAO90317.1 - 0.17 12.0 6.2 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) LRR_4 PF12799.2 GAO90318.1 - 3.4e-39 131.8 47.8 1e-08 34.5 0.4 9.7 7 1 1 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO90318.1 - 1.7e-31 107.7 43.2 2.6e-06 27.1 0.2 8.0 6 2 1 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 GAO90318.1 - 4.2e-22 74.7 50.4 0.0065 16.3 0.1 15.8 16 0 0 16 16 16 10 Leucine Rich Repeat LRR_7 PF13504.1 GAO90318.1 - 3.2e-16 56.5 47.6 0.061 13.5 0.1 14.6 15 0 0 15 15 15 7 Leucine rich repeat LRR_6 PF13516.1 GAO90318.1 - 1.3e-09 37.0 44.9 1.6 9.0 0.0 13.8 12 2 2 14 14 14 5 Leucine Rich repeat LRR_9 PF14580.1 GAO90318.1 - 0.0049 16.4 13.2 0.01 15.3 0.5 4.0 3 1 0 4 4 4 1 Leucine-rich repeat IncA PF04156.9 GAO90319.1 - 0.17 11.4 7.2 0.43 10.1 5.0 1.7 1 0 0 1 1 1 0 IncA protein Ribosomal_L13e PF01294.13 GAO90320.1 - 2.9e-64 215.8 9.2 1.8e-63 213.2 6.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L13e IncA PF04156.9 GAO90321.1 - 0.82 9.2 4.0 0.71 9.4 0.4 2.1 2 0 0 2 2 2 0 IncA protein Oxidored-like PF09791.4 GAO90322.1 - 8.8e-26 89.0 4.3 1.9e-25 88.0 3.0 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF3245 PF11595.3 GAO90323.1 - 1.6e-49 168.0 4.1 5.1e-49 166.3 2.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) DUF4604 PF15377.1 GAO90323.1 - 0.084 13.0 7.6 0.13 12.5 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PGA2 PF07543.7 GAO90323.1 - 5.1 6.8 6.5 4 7.2 0.8 2.3 1 1 1 2 2 2 0 Protein trafficking PGA2 HSF_DNA-bind PF00447.12 GAO90324.1 - 1.6e-36 124.6 0.5 3.1e-36 123.6 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding F-box PF00646.28 GAO90325.1 - 7.9e-05 22.2 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAO90325.1 - 0.0004 20.0 0.1 0.00095 18.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like ATP-grasp_2 PF08442.5 GAO90326.1 - 1e-78 263.3 0.5 1e-78 263.3 0.4 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 GAO90326.1 - 6.8e-25 87.4 0.3 1.4e-24 86.4 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 GAO90326.1 - 2.1e-07 30.4 1.3 4.2e-07 29.4 0.4 1.9 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 GAO90326.1 - 0.00015 21.3 1.7 0.0049 16.4 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 GAO90326.1 - 0.01 15.4 0.6 7.5 6.1 0.0 3.2 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 GAO90326.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Peripla_BP_2 PF01497.13 GAO90326.1 - 0.025 13.7 0.3 0.051 12.7 0.2 1.5 1 0 0 1 1 1 0 Periplasmic binding protein adh_short PF00106.20 GAO90327.1 - 8.4e-17 61.5 0.4 2.7e-13 50.1 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90327.1 - 2e-11 44.1 0.0 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAO90327.1 - 5e-05 22.5 0.0 0.015 14.4 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAO90327.1 - 0.00085 19.3 0.1 0.001 19.1 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAO90327.1 - 0.0011 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family PAE PF03283.8 GAO90327.1 - 0.51 8.9 2.2 0.66 8.5 0.0 1.9 2 0 0 2 2 2 0 Pectinacetylesterase SLAC1 PF03595.12 GAO90328.1 - 3.6e-17 62.0 17.0 4e-17 61.8 11.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Form-deh_trans PF09163.6 GAO90328.1 - 0.03 13.8 0.4 0.083 12.3 0.3 1.7 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane DUF912 PF06024.7 GAO90328.1 - 2.5 8.1 5.6 21 5.2 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2852 PF11014.3 GAO90328.1 - 4 7.4 5.5 2.3 8.2 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) UPF0259 PF06790.6 GAO90328.1 - 6.4 6.1 10.8 0.6 9.5 4.1 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0259) Pribosyltran PF00156.22 GAO90329.1 - 3e-08 33.4 0.1 1.3e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 GAO90330.1 - 1.3e-27 95.4 0.1 8.5e-27 92.8 0.1 1.8 1 1 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3618 PF12277.3 GAO90330.1 - 0.12 12.3 0.5 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) RecO_C PF02565.10 GAO90331.1 - 0.011 15.5 1.3 0.25 11.1 0.0 3.1 2 1 1 3 3 3 0 Recombination protein O C terminal Arm PF00514.18 GAO90331.1 - 0.014 15.2 1.5 8 6.4 0.1 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Acetyltransf_4 PF13420.1 GAO90331.1 - 0.098 12.6 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC1 PF03109.11 GAO90333.1 - 4.2e-21 75.1 0.0 2.4e-13 50.0 0.0 2.8 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.17 GAO90333.1 - 0.015 14.6 0.0 0.3 10.3 0.0 2.7 2 1 1 3 3 3 0 RIO1 family APH PF01636.18 GAO90333.1 - 0.015 15.0 0.2 0.11 12.2 0.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 GAO90334.1 - 1.4e-80 270.5 0.0 1.7e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.3 GAO90335.1 - 0.0017 17.0 0.0 0.02 13.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tricorn_C1 PF14684.1 GAO90335.1 - 0.099 12.5 1.0 0.25 11.2 0.7 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain UQ_con PF00179.21 GAO90336.1 - 3.7e-26 91.2 0.1 5.2e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 GAO90337.1 - 2.7e-33 115.8 0.0 3.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 GAO90337.1 - 0.00013 21.5 16.4 0.0017 17.9 11.4 2.3 1 1 0 1 1 1 1 Yip1 domain UFD1 PF03152.9 GAO90338.1 - 3.3e-24 84.9 0.0 3.9e-20 71.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zinc_ribbon_5 PF13719.1 GAO90338.1 - 6.6 6.4 10.1 11 5.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAO90338.1 - 7.7 6.3 9.9 16 5.2 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain F-box-like PF12937.2 GAO90339.1 - 0.0012 18.4 0.9 0.0041 16.8 0.1 2.4 3 0 0 3 3 3 1 F-box-like AAA PF00004.24 GAO90340.1 - 1.3e-43 148.3 0.0 2.2e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAO90340.1 - 2.4e-08 33.8 0.0 5.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAO90340.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAO90340.1 - 2.2e-06 27.7 0.1 1.8e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO90340.1 - 4e-06 27.0 0.1 0.00024 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAO90340.1 - 9.8e-05 23.1 0.0 0.00023 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAO90340.1 - 0.00012 21.7 0.1 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 GAO90340.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAO90340.1 - 0.00039 19.8 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAO90340.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAO90340.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAO90340.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAO90340.1 - 0.0026 16.8 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 GAO90340.1 - 0.0038 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAO90340.1 - 0.004 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 GAO90340.1 - 0.0045 16.1 0.1 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAO90340.1 - 0.005 15.9 0.1 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 GAO90340.1 - 0.0057 16.9 0.0 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAO90340.1 - 0.018 14.2 0.0 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 GAO90340.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAO90340.1 - 0.02 14.3 0.1 0.096 12.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 GAO90340.1 - 0.02 13.7 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAO90340.1 - 0.025 13.9 0.1 0.056 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2072 PF09845.4 GAO90340.1 - 0.029 14.3 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 GAO90340.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 GAO90340.1 - 0.047 13.7 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 GAO90340.1 - 0.05 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 GAO90340.1 - 0.07 12.7 0.0 0.54 9.8 0.0 2.1 1 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 GAO90340.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 GAO90340.1 - 0.098 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Na_Ca_ex PF01699.19 GAO90341.1 - 1.9e-31 108.5 24.3 4.6e-19 68.3 7.1 3.8 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAO90341.1 - 5.1e-14 52.4 12.7 5.1e-14 52.4 8.8 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF307) FGGY_C PF02782.11 GAO90342.1 - 1.1e-54 185.1 0.1 1.7e-54 184.4 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAO90342.1 - 3.4e-24 85.5 0.1 1.6e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 GAO90342.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.2 GAO90344.1 - 0.0034 17.0 1.2 0.0063 16.2 0.8 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO90344.1 - 0.012 15.2 0.4 0.022 14.3 0.2 1.4 1 0 0 1 1 1 0 F-box domain Y_phosphatase PF00102.22 GAO90345.1 - 1.1e-41 142.7 0.7 6.7e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 GAO90345.1 - 9e-07 29.2 0.0 1.7e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 GAO90345.1 - 0.00088 18.8 0.2 0.0024 17.4 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAO90345.1 - 0.0021 18.3 0.6 0.0091 16.2 0.3 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family Nic96 PF04097.9 GAO90346.1 - 1e-216 720.8 0.0 1.2e-216 720.6 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 GAO90346.1 - 3.9e-05 23.8 23.0 3.9e-05 23.8 15.9 2.0 2 0 0 2 2 2 1 Nucleoporin FG repeat region RibD_C PF01872.12 GAO90347.1 - 4.4e-30 104.7 0.0 5.9e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain RCC1 PF00415.13 GAO90348.1 - 1.1e-57 191.9 13.0 9.3e-13 48.1 0.1 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAO90348.1 - 1.5e-37 126.3 40.3 9.3e-10 37.8 0.4 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Swi3 PF07962.7 GAO90349.1 - 2.1e-32 110.6 0.2 3.2e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.4 GAO90350.1 - 9.8e-37 125.0 0.2 1.4e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 GAO90350.1 - 5.8e-35 118.8 0.1 8.3e-35 118.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit AAA PF00004.24 GAO90351.1 - 4.7e-63 211.2 0.0 2.9e-42 143.9 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAO90351.1 - 2e-10 40.9 2.0 0.00092 19.2 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain Bac_DnaA PF00308.13 GAO90351.1 - 1.9e-08 34.2 0.0 3.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.9 GAO90351.1 - 4.6e-08 32.8 0.3 0.0023 17.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAO90351.1 - 4.8e-07 29.9 5.7 0.48 10.5 0.1 5.2 2 2 2 4 4 4 2 AAA domain Arch_ATPase PF01637.13 GAO90351.1 - 6.8e-07 29.2 0.0 0.023 14.4 0.0 3.0 2 1 1 3 3 3 2 Archaeal ATPase TIP49 PF06068.8 GAO90351.1 - 2.6e-06 26.4 0.0 0.011 14.4 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 GAO90351.1 - 5.1e-06 26.4 0.0 0.077 12.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAO90351.1 - 8.9e-06 25.2 0.0 0.024 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 GAO90351.1 - 2.4e-05 24.4 0.0 0.3 11.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.8 GAO90351.1 - 5.8e-05 22.1 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAO90351.1 - 5.9e-05 23.8 0.0 0.26 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAO90351.1 - 8.9e-05 22.5 0.0 0.4 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 GAO90351.1 - 0.00033 19.7 0.0 0.057 12.4 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 GAO90351.1 - 0.00034 19.4 0.0 0.0014 17.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 GAO90351.1 - 0.00036 20.2 0.3 0.8 9.4 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 GAO90351.1 - 0.00059 19.5 4.2 0.36 10.4 0.2 3.7 2 2 2 4 4 4 2 NACHT domain AAA_2 PF07724.9 GAO90351.1 - 0.00077 19.4 0.0 0.0046 16.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 GAO90351.1 - 0.0011 18.3 5.8 1.9 7.8 0.1 4.2 2 2 1 3 3 3 1 AAA domain DAP3 PF10236.4 GAO90351.1 - 0.0091 14.9 0.0 0.045 12.6 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Sigma54_activ_2 PF14532.1 GAO90351.1 - 0.01 15.9 0.0 0.56 10.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 GAO90351.1 - 0.019 14.0 0.1 3.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.16 GAO90351.1 - 0.02 14.0 0.4 3 6.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 GAO90351.1 - 0.037 14.3 0.1 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 GAO90351.1 - 0.062 12.8 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 GAO90351.1 - 0.07 12.7 1.0 4.6 6.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAO90351.1 - 0.1 12.4 0.0 13 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAO90351.1 - 0.16 12.2 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NCA2 PF08637.5 GAO90352.1 - 1e-69 234.6 0.0 1.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 GAO90352.1 - 1.4e-64 216.3 0.0 2e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO90352.1 - 3.8e-18 66.1 0.0 6.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO90352.1 - 8.2e-14 51.2 0.1 1.4e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAO90352.1 - 5.3e-06 25.9 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAO90352.1 - 1.3e-05 24.4 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAO90352.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 GAO90352.1 - 0.14 11.4 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 GAO90352.1 - 0.14 11.3 0.1 0.56 9.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FA_hydroxylase PF04116.8 GAO90353.1 - 3.9e-16 59.4 18.6 3.9e-16 59.4 12.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PSDC PF12588.3 GAO90355.1 - 4.2e-33 113.9 0.0 6e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 GAO90355.1 - 5.2e-31 107.5 0.0 7.6e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTS_EIIA_1 PF00358.15 GAO90355.1 - 0.04 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ILVD_EDD PF00920.16 GAO90356.1 - 1e-13 50.5 0.0 1.2e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family VitD-bind_III PF09164.5 GAO90357.1 - 0.099 12.2 1.1 0.74 9.4 0.0 2.9 3 0 0 3 3 3 0 Vitamin D binding protein, domain III Gly-zipper_OmpA PF13436.1 GAO90357.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Endotoxin_C PF03944.9 GAO90359.1 - 0.061 13.4 0.5 0.74 9.9 0.0 2.6 3 0 0 3 3 3 0 delta endotoxin Ank_2 PF12796.2 GAO90360.1 - 3e-54 181.3 1.1 3.6e-15 56.0 0.0 4.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO90360.1 - 7e-49 163.3 7.8 6.6e-14 51.9 0.0 6.8 3 3 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAO90360.1 - 1.4e-48 160.3 9.4 2.3e-07 30.2 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 GAO90360.1 - 4.9e-39 131.4 19.5 7e-09 35.6 0.3 8.6 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO90360.1 - 1.9e-36 120.4 2.4 2.5e-05 24.0 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Glyco_hydro_35 PF01301.14 GAO90362.1 - 4.2e-92 308.9 0.6 5.2e-92 308.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAO90362.1 - 4.6e-63 211.8 4.7 7e-63 211.2 3.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAO90362.1 - 1.8e-56 189.1 12.2 1.4e-29 102.6 1.9 3.6 3 0 0 3 3 3 3 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAO90362.1 - 6.5e-24 83.1 0.0 2.7e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Oxidored_FMN PF00724.15 GAO90363.1 - 7.9e-09 34.9 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HMGL-like PF00682.14 GAO90365.1 - 4.2e-41 141.1 0.0 6.4e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 GAO90365.1 - 1.1e-39 136.1 0.0 1.9e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 GAO90366.1 - 3.2e-89 299.2 0.0 3.8e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAO90366.1 - 6.3e-13 49.4 0.0 2.6e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L7Ae PF01248.21 GAO90366.1 - 0.15 11.5 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Carboxyl_trans PF01039.17 GAO90367.1 - 1.3e-122 409.6 0.0 1.5e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAO90368.1 - 3.7e-70 235.5 0.4 7.5e-70 234.4 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAO90368.1 - 5.2e-37 126.3 0.9 1.2e-36 125.1 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAO90368.1 - 1.1e-33 115.4 0.0 2.2e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAO90368.1 - 3.6e-15 56.1 0.1 6.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAO90368.1 - 8.6e-12 44.5 1.4 2e-11 43.3 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAO90368.1 - 1.1e-11 44.0 0.0 2.1e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAO90368.1 - 2.6e-09 36.6 0.2 6.7e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAO90368.1 - 4.4e-09 36.0 0.0 9.1e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAO90368.1 - 9.7e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAO90368.1 - 2e-05 24.1 0.0 0.0001 21.8 0.0 2.1 2 1 0 2 2 2 1 RimK-like ATP-grasp domain SUI1 PF01253.17 GAO90368.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor SUI1 HlyD_3 PF13437.1 GAO90368.1 - 0.043 14.1 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 GAO90368.1 - 0.17 10.9 0.1 0.54 9.3 0.0 1.6 1 1 1 2 2 2 0 HlyD family secretion protein Mito_carr PF00153.22 GAO90369.1 - 5e-32 109.4 0.1 5.2e-11 42.1 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 GAO90369.1 - 8.7e-28 97.3 2.0 1.7e-27 96.3 1.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 GAO90369.1 - 1.8e-20 72.9 0.0 3.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_N PF02771.11 GAO90369.1 - 1.4e-19 70.6 0.0 5.9e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAO90369.1 - 1.7e-19 69.0 0.8 3.5e-19 68.0 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Zn_clus PF00172.13 GAO90369.1 - 5.2e-08 32.6 11.5 1.4e-07 31.3 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1996 PF09362.5 GAO90370.1 - 1.5e-65 221.1 0.0 2.2e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 GAO90370.1 - 2e-17 62.8 9.9 5.7e-17 61.4 6.9 1.8 1 0 0 1 1 1 1 WSC domain KR PF08659.5 GAO90371.1 - 5.9e-58 195.4 1.1 1.6e-57 194.0 0.8 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO90371.1 - 9.5e-44 149.2 2.1 1.4e-43 148.7 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 GAO90371.1 - 8.9e-16 57.6 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO90371.1 - 1.6e-10 41.9 0.0 4.4e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAO90371.1 - 1.1e-06 28.7 0.1 4.3e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAO90371.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 GAO90372.1 - 5.1e-47 160.4 0.0 6.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 GAO90373.1 - 2.7e-67 226.9 0.2 8.7e-67 225.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO90373.1 - 2.3e-52 178.2 0.0 4.2e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAO90373.1 - 9.3e-49 166.1 0.7 1.5e-48 165.4 0.5 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAO90373.1 - 8.2e-45 152.6 0.0 2.8e-44 150.9 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAO90373.1 - 1.3e-34 119.4 0.0 4.2e-34 117.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO90373.1 - 1.9e-32 111.6 0.1 4.5e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAO90373.1 - 6.7e-05 23.0 0.5 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAO90373.1 - 0.00095 18.2 0.0 0.0024 16.9 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 GAO90373.1 - 0.0046 17.4 0.0 0.016 15.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90373.1 - 0.0072 16.0 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 GAO90374.1 - 1.8e-22 80.3 1.7 2.7e-22 79.7 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO90374.1 - 5.3e-08 32.7 0.1 9.6e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO90374.1 - 2.2e-06 27.4 0.1 5.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.13 GAO90375.1 - 2.6e-28 98.8 0.0 3.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO90375.1 - 0.0017 18.9 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90375.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90375.1 - 0.043 14.2 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 GAO90377.1 - 2.4e-45 154.9 0.0 3e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 GAO90378.1 - 1.7e-15 57.1 0.1 8.9e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAO90378.1 - 1.4e-12 46.9 0.0 2.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAO90378.1 - 3.1e-11 43.6 0.0 5.3e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAO90378.1 - 0.00012 21.0 0.0 0.069 12.0 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 GAO90378.1 - 0.00077 18.7 0.0 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAO90378.1 - 0.0042 16.0 0.0 0.0073 15.2 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAO90378.1 - 0.011 15.7 0.0 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Aminotran_4 PF01063.14 GAO90380.1 - 1e-21 77.5 0.0 1.4e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ATP_bind_3 PF01171.15 GAO90380.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 PP-loop family Pyr_redox_3 PF13738.1 GAO90381.1 - 1.1e-26 94.1 0.1 2.6e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO90381.1 - 4.2e-11 43.0 0.0 8.6e-10 38.8 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAO90381.1 - 7.8e-11 40.8 0.0 6.7e-10 37.7 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAO90381.1 - 8e-10 38.1 0.2 1.5e-07 30.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAO90381.1 - 1.1e-05 24.7 0.1 0.035 13.1 0.6 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAO90381.1 - 6.7e-05 22.8 0.0 0.00024 21.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAO90381.1 - 0.0016 18.7 0.2 0.38 11.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO90381.1 - 0.002 17.0 0.3 0.58 9.0 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAO90381.1 - 0.0056 16.7 0.2 2.5 8.2 0.0 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 GAO90381.1 - 0.011 14.2 0.1 0.66 8.3 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 GAO90381.1 - 0.018 14.2 0.1 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAO90381.1 - 0.018 14.8 1.5 5 6.8 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAO90381.1 - 0.018 13.9 0.2 0.063 12.1 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 GAO90381.1 - 0.036 14.0 0.2 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 GAO90381.1 - 0.25 10.1 0.1 3.7 6.3 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 GAO90382.1 - 2.9e-40 137.3 0.3 4.1e-26 91.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 GAO90382.1 - 0.035 12.9 0.1 0.044 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.1 GAO90382.1 - 0.039 14.2 0.0 0.098 12.9 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 GAO90382.1 - 0.049 13.2 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 GAO90382.1 - 0.1 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_zinc_N PF00107.21 GAO90383.1 - 4e-12 45.8 0.0 1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90383.1 - 5.9e-06 26.0 0.0 0.00017 21.3 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO90383.1 - 0.001 19.9 0.0 0.0024 18.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_N PF02776.13 GAO90384.1 - 2e-34 118.5 0.2 3.9e-34 117.6 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAO90384.1 - 3.6e-17 62.4 0.0 7.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAO90384.1 - 7.4e-13 48.3 0.0 2.2e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Methyltransf_2 PF00891.13 GAO90385.1 - 1.5e-26 93.0 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAO90385.1 - 9.1e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 GAO90385.1 - 0.0029 17.0 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 GAO90385.1 - 0.0058 16.0 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MTS PF05175.9 GAO90385.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain CheR PF01739.13 GAO90385.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 GAO90386.1 - 3.4e-05 24.1 0.0 8.3e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain EB PF01683.13 GAO90387.1 - 6.4 6.9 83.4 0.11 12.5 2.6 12.8 2 2 3 5 5 5 0 EB module UMPH-1 PF05822.7 GAO90388.1 - 1.2 8.3 4.2 0.57 9.4 1.0 1.7 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) GMC_oxred_C PF05199.8 GAO90389.1 - 1.3e-20 74.1 0.5 2.4e-14 53.8 0.2 2.1 1 1 1 2 2 2 2 GMC oxidoreductase K_trans PF02705.11 GAO90390.1 - 5.5e-177 589.3 16.2 6.5e-177 589.1 11.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF3508 PF12018.3 GAO90390.1 - 0.24 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Hemopexin PF00045.14 GAO90391.1 - 0.00072 19.2 0.4 0.0013 18.4 0.3 1.5 1 1 0 1 1 1 1 Hemopexin DUF3662 PF12401.3 GAO90392.1 - 0.078 13.1 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) ILVD_EDD PF00920.16 GAO90394.1 - 6.9e-158 526.3 0.1 7.8e-158 526.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.13 GAO90395.1 - 1.1e-20 73.6 1.2 1.8e-20 72.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.9 GAO90396.1 - 1.3e-100 336.3 0.0 1.6e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase adh_short_C2 PF13561.1 GAO90397.1 - 2.1e-33 116.0 0.1 2.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO90397.1 - 8.1e-25 87.6 0.1 1.2e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90397.1 - 5e-07 29.5 0.1 7.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NusB PF01029.13 GAO90397.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 NusB family ECH PF00378.15 GAO90398.1 - 3.2e-40 137.8 0.0 2.9e-38 131.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Velvet PF11754.3 GAO90399.1 - 0.042 13.4 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Velvet factor Glyco_hydro_43 PF04616.9 GAO90400.1 - 7.8e-33 113.7 4.1 2.1e-32 112.3 2.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Pec_lyase_C PF00544.14 GAO90400.1 - 3.4e-19 69.1 7.3 7.6e-19 67.9 5.1 1.6 1 0 0 1 1 1 1 Pectate lyase Fungal_trans_2 PF11951.3 GAO90400.1 - 0.0019 16.9 0.0 0.0041 15.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SPRY PF00622.23 GAO90400.1 - 0.017 15.2 0.3 0.052 13.6 0.2 1.8 1 0 0 1 1 1 0 SPRY domain Gemini_AL2 PF01440.11 GAO90400.1 - 0.11 12.6 0.2 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein PD40 PF07676.7 GAO90401.1 - 0.00013 21.5 0.2 0.017 14.8 0.1 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Lipase_3 PF01764.20 GAO90402.1 - 2.5e-36 124.4 0.0 3.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 GAO90402.1 - 4.8e-17 61.5 0.2 1.1e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.2 GAO90402.1 - 4.2e-05 23.5 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 GAO90402.1 - 4.4e-05 23.0 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_5 PF12695.2 GAO90402.1 - 4.7e-05 23.1 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAO90402.1 - 0.00093 18.6 0.4 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 GAO90402.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAO90402.1 - 0.0037 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 GAO90402.1 - 0.0048 16.4 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 GAO90402.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.15 GAO90402.1 - 0.032 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase VirJ PF06057.6 GAO90402.1 - 0.037 13.8 0.1 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DLH PF01738.13 GAO90402.1 - 0.061 12.6 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.15 GAO90402.1 - 0.09 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 GAO90402.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 GAO90403.1 - 4e-22 79.1 0.0 4.9e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAO90403.1 - 1.3e-12 47.9 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90403.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAO90403.1 - 0.0023 17.9 0.1 0.0071 16.3 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO90403.1 - 0.036 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAO90403.1 - 0.084 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 GAO90404.1 - 1.7e-12 47.0 1.0 2.9e-12 46.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90404.1 - 1.2e-11 44.3 0.0 3.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 GAO90405.1 - 3.4e-16 59.2 0.0 5.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90405.1 - 6.2e-11 42.6 0.0 3.2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding GST_C PF00043.20 GAO90405.1 - 1.6e-09 37.6 0.0 3.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO90405.1 - 1.7e-09 37.6 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO90405.1 - 2.2e-07 30.9 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO90405.1 - 1.2e-06 28.2 0.2 3.1e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAO90405.1 - 0.00061 20.2 0.1 0.0013 19.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAO90405.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 3Beta_HSD PF01073.14 GAO90405.1 - 0.032 12.9 0.0 0.086 11.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3425 PF11905.3 GAO90406.1 - 9.9e-33 112.9 0.6 1.2e-32 112.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MFS_1 PF07690.11 GAO90407.1 - 1.5e-33 116.0 36.2 1.5e-33 116.0 25.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Trypsin PF00089.21 GAO90408.1 - 2.5e-36 125.3 0.0 3.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 GAO90408.1 - 1.6e-05 24.8 0.1 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain FAD_binding_3 PF01494.14 GAO90409.1 - 9.2e-18 64.4 3.7 9.5e-17 61.0 2.5 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90409.1 - 2e-09 36.8 5.0 0.00014 20.8 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO90409.1 - 4.7e-07 29.0 1.6 1.6e-06 27.2 0.3 2.2 1 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAO90409.1 - 7.1e-07 28.0 0.3 0.0015 17.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 GAO90409.1 - 0.00013 21.9 0.8 0.00081 19.3 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO90409.1 - 0.00061 20.1 0.7 0.24 11.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO90409.1 - 0.0012 17.7 0.7 0.0017 17.2 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAO90409.1 - 0.0027 17.7 0.1 0.008 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAO90409.1 - 0.0052 15.9 0.3 0.0071 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO90409.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 GAO90409.1 - 0.065 12.6 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 GAO90410.1 - 3.5e-12 46.0 4.3 2.6e-09 36.6 3.0 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90410.1 - 1.6e-06 27.2 2.2 0.017 14.0 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO90410.1 - 0.00017 20.6 0.2 0.00036 19.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAO90410.1 - 0.0092 14.4 0.1 0.016 13.6 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAO90410.1 - 0.014 15.3 0.5 0.036 13.9 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO90410.1 - 0.02 13.7 2.2 0.092 11.5 1.5 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAO90410.1 - 0.089 12.8 0.2 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.23 GAO90411.1 - 1e-75 254.7 0.0 1.5e-75 254.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAO90411.1 - 2.3e-24 85.7 0.2 7.6e-23 80.8 0.0 2.4 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 GAO90411.1 - 6.9e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO90411.1 - 0.032 15.1 0.1 0.16 12.9 0.1 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 GAO90412.1 - 4.3e-248 822.5 0.0 2.3e-86 289.8 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAO90412.1 - 3.6e-141 469.3 0.1 4.8e-38 130.7 2.4 4.7 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAO90412.1 - 2.6e-34 117.3 0.3 6.9e-13 48.6 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO90412.1 - 7.8e-15 55.5 0.4 0.00047 21.0 0.0 4.4 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.18 GAO90413.1 - 1.3e-22 79.7 0.5 6.1e-22 77.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAO90413.1 - 1.1e-07 31.5 0.1 3.4e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Aldolase_II PF00596.16 GAO90414.1 - 1.1e-42 145.7 0.1 1.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2OG-Fe_Oxy_2 PF10014.4 GAO90415.1 - 4.1e-42 143.7 0.2 5.2e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase DUF1446 PF07287.6 GAO90416.1 - 1.8e-28 99.0 0.0 2.1e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Peptidase_M35 PF02102.10 GAO90417.1 - 3.7e-171 568.6 13.9 5e-171 568.2 9.6 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAO90417.1 - 2e-09 38.1 0.5 4.7e-09 36.9 0.3 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 GAO90417.1 - 1.4e-06 27.9 1.9 4.3e-06 26.3 1.1 2.0 1 1 1 2 2 2 1 Putative peptidase family Abhydrolase_1 PF00561.15 GAO90418.1 - 3e-13 49.8 0.1 1.1e-11 44.6 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAO90418.1 - 2.7e-08 33.9 0.0 8.8e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 GAO90418.1 - 2.1e-07 30.7 0.0 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein ADH_N PF08240.7 GAO90419.1 - 6.1e-30 103.1 2.0 1.2e-29 102.2 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.3 GAO90419.1 - 7.1e-05 21.5 3.0 0.00016 20.4 2.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N_assoc PF13823.1 GAO90419.1 - 0.00011 21.7 0.1 0.00029 20.4 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 GAO90419.1 - 0.001 18.6 0.0 0.0053 16.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 GAO90420.1 - 5.3e-08 32.2 0.0 8.4e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Aa_trans PF01490.13 GAO90421.1 - 8.7e-38 129.8 31.5 1e-37 129.6 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WHIM1 PF15612.1 GAO90423.1 - 0.099 12.6 0.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 1 Peptidase_M28 PF04389.12 GAO90424.1 - 1.2e-32 113.0 0.0 3.2e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 GAO90424.1 - 6.7e-14 51.4 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Pyr_redox_2 PF07992.9 GAO90425.1 - 3.2e-15 56.5 0.0 7.4e-05 22.7 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO90425.1 - 1.3e-14 54.2 0.2 4e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO90425.1 - 4.7e-10 38.8 0.2 0.013 14.4 0.0 3.5 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAO90425.1 - 6.2e-10 39.4 0.0 0.00066 19.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAO90425.1 - 1.9e-07 30.3 0.0 6.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAO90425.1 - 1.9e-05 24.8 0.0 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 GAO90425.1 - 4.9e-05 22.1 0.1 0.22 10.0 0.0 2.6 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 GAO90425.1 - 8.2e-05 22.5 0.0 0.46 10.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 GAO90425.1 - 0.00035 20.5 0.1 0.27 11.2 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 GAO90425.1 - 0.00048 19.1 0.0 0.18 10.6 0.0 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAO90425.1 - 0.01 15.6 0.2 9.6 5.9 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAO90425.1 - 0.063 11.7 0.0 4.5 5.6 0.0 2.4 1 1 1 2 2 2 0 HI0933-like protein ApbA PF02558.11 GAO90425.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 GAO90425.1 - 0.11 11.5 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DUF2236 PF09995.4 GAO90427.1 - 4.7e-52 176.6 5.4 6.2e-52 176.3 3.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Dehydratase_hem PF13816.1 GAO90428.1 - 3.2e-110 367.9 0.9 3.7e-110 367.8 0.7 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 GAO90428.1 - 8.9e-08 32.2 0.1 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Na_Ca_ex PF01699.19 GAO90429.1 - 5.5e-20 71.3 31.7 4.3e-14 52.3 10.9 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Aa_trans PF01490.13 GAO90431.1 - 1.1e-79 267.8 21.9 1.5e-79 267.4 15.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_M20 PF01546.23 GAO90432.1 - 1.9e-26 92.7 0.1 3.1e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 FA_hydroxylase PF04116.8 GAO90432.1 - 3e-12 46.9 14.8 3e-12 46.9 10.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily M20_dimer PF07687.9 GAO90432.1 - 5.7e-06 26.0 0.1 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO90432.1 - 2.9e-05 23.8 0.0 5.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PALP PF00291.20 GAO90433.1 - 2.1e-55 188.1 1.9 2.1e-55 188.1 1.3 1.9 2 1 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 GAO90433.1 - 1.6e-34 119.0 0.2 4.1e-34 117.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAO90433.1 - 3.7e-18 65.2 0.0 1.7e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO90433.1 - 0.0025 17.5 0.1 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CoA_transf_3 PF02515.12 GAO90433.1 - 0.0095 15.1 0.3 0.02 14.1 0.2 1.4 1 0 0 1 1 1 1 CoA-transferase family III DUF3674 PF12426.3 GAO90433.1 - 0.2 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase Homeobox_KN PF05920.6 GAO90434.1 - 1.1e-13 50.6 3.0 1.2e-13 50.4 0.4 2.5 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2_4 PF13894.1 GAO90434.1 - 5.5e-07 29.4 29.0 0.11 12.9 2.5 5.9 4 1 0 4 4 4 3 C2H2-type zinc finger Homeobox PF00046.24 GAO90434.1 - 3e-05 23.5 1.0 7.2e-05 22.3 0.7 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 GAO90434.1 - 0.17 12.2 30.4 0.042 14.1 2.8 5.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type Zn_clus PF00172.13 GAO90434.1 - 1.7 8.6 11.5 0.13 12.2 3.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PTR2 PF00854.16 GAO90437.1 - 7.7e-29 100.6 8.2 1.7e-28 99.4 5.7 1.6 1 1 0 1 1 1 1 POT family Acetyltransf_7 PF13508.1 GAO90438.1 - 5.3e-09 36.1 0.0 2.3e-08 34.0 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO90438.1 - 1e-07 31.8 0.0 7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAO90438.1 - 1.8e-06 28.0 0.0 5.4e-05 23.2 0.0 2.4 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAO90438.1 - 2.8e-06 27.2 0.0 0.00011 22.1 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO90438.1 - 0.00027 20.6 0.0 0.017 14.8 0.0 2.5 2 2 0 2 2 2 1 FR47-like protein MOZ_SAS PF01853.13 GAO90438.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family GNAT_acetyltr_2 PF13718.1 GAO90438.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_7 PF13508.1 GAO90439.1 - 3.4e-07 30.3 0.0 1.3e-06 28.4 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO90439.1 - 1.4e-06 28.2 0.1 4.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAO90439.1 - 5.1e-06 26.3 0.0 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO90439.1 - 0.00061 19.4 0.0 0.0044 16.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 GAO90439.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DBP10CT PF08147.7 GAO90439.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Acetyltransf_10 PF13673.1 GAO90439.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 GAO90440.1 - 4.5e-34 116.6 0.0 2.1e-08 34.3 0.0 6.7 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAO90440.1 - 4.1e-26 89.4 3.9 1.3e-05 24.7 0.0 8.3 8 1 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 GAO90440.1 - 6.5e-23 80.6 0.3 0.00059 20.2 0.1 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO90440.1 - 3.1e-21 74.9 5.9 2.8e-05 24.1 0.0 7.5 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO90440.1 - 8e-18 62.7 5.1 0.00047 20.1 0.0 9.0 11 0 0 11 11 11 4 Ankyrin repeat Zn_clus PF00172.13 GAO90441.1 - 1.2e-07 31.5 13.0 1.7e-07 31.0 9.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAO90442.1 - 1.6e-19 70.4 0.4 2.2e-19 70.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90442.1 - 2.3e-09 37.2 0.0 4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAO90442.1 - 7.6e-06 25.8 0.0 9.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAO90442.1 - 0.00023 20.1 0.0 0.0021 16.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAO90442.1 - 0.00047 19.8 0.1 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAO90442.1 - 0.0085 15.5 0.4 0.054 12.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAO90442.1 - 0.078 12.3 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PAN_4 PF14295.1 GAO90443.1 - 0.0001 21.9 0.8 0.00026 20.6 0.6 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 GAO90443.1 - 0.0019 17.8 1.2 0.0029 17.3 0.3 1.7 1 1 0 1 1 1 1 PAN domain PAN_3 PF08277.7 GAO90443.1 - 0.015 14.9 0.2 0.015 14.9 0.1 1.6 2 0 0 2 2 2 0 PAN-like domain cEGF PF12662.2 GAO90444.1 - 0.1 12.2 0.2 0.1 12.2 0.2 17.0 17 4 2 19 19 19 0 Complement Clr-like EGF-like Amidase PF01425.16 GAO90445.1 - 9e-34 117.0 0.5 2.9e-33 115.3 0.4 1.6 2 0 0 2 2 2 1 Amidase DAO PF01266.19 GAO90446.1 - 5e-17 61.8 0.7 8.7e-16 57.7 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase DUF3632 PF12311.3 GAO90447.1 - 3.7e-41 140.9 0.0 4.8e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_transf_90 PF05686.7 GAO90448.1 - 9.1e-29 100.3 0.0 1.2e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 MU117 PF15474.1 GAO90448.1 - 6.3e-11 42.6 5.7 1.7e-10 41.2 4.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene family DUF1564 PF07600.6 GAO90448.1 - 0.0032 16.8 0.4 0.0082 15.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Glyco_trans_1_2 PF13524.1 GAO90448.1 - 0.008 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Aminotran_4 PF01063.14 GAO90449.1 - 5.4e-31 107.8 0.0 6.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV adh_short_C2 PF13561.1 GAO90450.1 - 3.5e-24 85.8 0.0 7.2e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 GAO90450.1 - 3.1e-22 79.2 0.2 9.2e-22 77.7 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAO90450.1 - 7e-12 45.2 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAO90450.1 - 4.9e-06 26.5 0.0 1.3e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90450.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 KR domain Thiolase_N PF00108.18 GAO90450.1 - 0.09 11.7 0.2 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain 2-Hacid_dh_C PF02826.14 GAO90450.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAO90450.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Acyl_transf_1 PF00698.16 GAO90451.1 - 1.1e-51 176.0 0.0 2.6e-50 171.5 0.0 2.9 3 0 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 GAO90451.1 - 1.6e-29 101.4 0.2 1.1e-28 98.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 GAO90451.1 - 1.9e-25 88.6 0.0 5.6e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAO90451.1 - 1.9e-19 69.7 0.0 6e-18 64.9 0.0 3.2 4 0 0 4 4 4 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAO90451.1 - 0.044 12.9 2.0 0.09 11.9 0.1 2.2 2 1 0 2 2 2 0 Nitronate monooxygenase p450 PF00067.17 GAO90452.1 - 4e-62 210.2 0.0 5.3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 GAO90453.1 - 0 1388.7 0.0 7.8e-89 297.9 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 GAO90453.1 - 1.4e-278 920.5 5.0 7.8e-53 179.2 0.0 7.4 7 0 0 7 7 7 7 Condensation domain PP-binding PF00550.20 GAO90453.1 - 1.6e-57 191.6 8.6 1.3e-09 38.1 0.0 7.7 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAO90453.1 - 1.8e-39 134.5 10.6 2.1e-08 35.0 0.0 6.8 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain AATase PF07247.7 GAO90453.1 - 1.1e-08 34.1 0.0 0.8 8.1 0.0 6.8 7 1 0 7 7 7 3 Alcohol acetyltransferase HxxPF_rpt PF13745.1 GAO90453.1 - 9.3e-08 32.2 0.9 0.00029 21.0 0.0 4.7 4 0 0 4 4 4 1 HxxPF-repeated domain Transferase PF02458.10 GAO90453.1 - 6.3e-06 24.9 0.0 0.15 10.5 0.0 3.9 4 0 0 4 4 4 3 Transferase family GH3 PF03321.8 GAO90453.1 - 0.025 13.1 1.2 0.59 8.5 0.0 3.3 4 0 0 4 4 4 0 GH3 auxin-responsive promoter DUF4295 PF14128.1 GAO90453.1 - 3.7 7.2 0.0 9.2 5.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) FA_desaturase PF00487.19 GAO90454.1 - 2.4e-12 46.8 29.0 2.4e-12 46.8 20.1 2.0 1 1 1 2 2 2 1 Fatty acid desaturase ABC_tran PF00005.22 GAO90455.1 - 5.8e-41 139.9 0.1 1.5e-28 99.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO90455.1 - 5.7e-34 117.7 23.2 2e-22 79.8 9.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO90455.1 - 9.4e-10 38.0 1.1 4.6e-05 22.7 0.0 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO90455.1 - 5.2e-09 36.4 0.0 0.83 9.5 0.0 4.3 3 1 0 4 4 4 3 AAA domain Miro PF08477.8 GAO90455.1 - 3.3e-05 24.3 0.0 0.27 11.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAO90455.1 - 4.2e-05 22.9 0.5 0.014 14.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO90455.1 - 5.2e-05 22.4 0.2 0.013 14.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAO90455.1 - 0.00011 22.2 0.2 0.32 10.9 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAO90455.1 - 0.00052 20.1 0.5 1.1 9.4 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA PF00004.24 GAO90455.1 - 0.0011 19.1 1.5 1.7 8.8 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAO90455.1 - 0.002 18.5 0.1 0.093 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAO90455.1 - 0.0025 17.6 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAO90455.1 - 0.003 17.4 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAO90455.1 - 0.0097 15.7 0.0 5.7 6.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 GAO90455.1 - 0.015 14.8 0.2 0.48 9.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 GAO90455.1 - 0.017 15.0 0.1 0.79 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAO90455.1 - 0.018 14.7 0.1 0.07 12.8 0.0 2.1 3 0 0 3 3 2 0 Archaeal ATPase Zeta_toxin PF06414.7 GAO90455.1 - 0.036 13.1 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 GAO90455.1 - 0.055 14.2 0.1 12 6.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAO90455.1 - 0.097 11.5 2.7 8.7 5.1 0.1 3.5 3 1 0 3 3 3 0 NB-ARC domain MobB PF03205.9 GAO90455.1 - 0.23 11.1 0.8 12 5.5 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RTA1 PF04479.8 GAO90456.1 - 1.5e-36 125.9 6.9 2.4e-36 125.3 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DEC-1_N PF04625.8 GAO90456.1 - 0.38 9.3 3.7 0.56 8.8 2.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pectate_lyase_3 PF12708.2 GAO90457.1 - 5.3e-50 170.6 22.0 7.6e-39 134.1 8.3 4.0 3 1 1 4 4 4 2 Pectate lyase superfamily protein 4HBT_2 PF13279.1 GAO90457.1 - 1.2e-05 25.6 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily SLT PF01464.15 GAO90457.1 - 3.3e-05 23.3 1.2 8.3e-05 22.0 0.3 2.1 2 0 0 2 2 2 1 Transglycosylase SLT domain End_N_terminal PF12218.3 GAO90457.1 - 0.04 13.3 1.8 0.12 11.9 0.1 2.6 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Abhydrolase_6 PF12697.2 GAO90458.1 - 2.2e-27 96.4 0.1 2.6e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO90458.1 - 1.3e-12 47.7 0.0 3.2e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO90458.1 - 1.1e-11 44.6 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAO90458.1 - 4e-06 26.5 0.1 5.5e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 GAO90458.1 - 1e-05 25.2 0.2 2.4e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAO90458.1 - 0.00011 22.5 0.0 0.00017 21.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 GAO90458.1 - 0.00033 20.1 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 GAO90458.1 - 0.0021 17.8 0.0 0.0071 16.1 0.0 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 GAO90458.1 - 0.0023 17.5 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 GAO90458.1 - 0.0046 16.4 0.2 0.27 10.6 0.1 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF900 PF05990.7 GAO90458.1 - 0.012 15.0 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 GAO90458.1 - 0.093 12.3 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.15 GAO90458.1 - 0.14 11.5 3.8 0.64 9.3 0.3 2.6 1 1 1 2 2 2 0 Putative esterase Chlorophyllase PF07224.6 GAO90458.1 - 0.2 10.4 0.4 1.2 7.8 0.1 2.0 1 1 1 2 2 2 0 Chlorophyllase Hexokinase_2 PF03727.11 GAO90459.1 - 6.2e-80 267.9 0.0 8.2e-80 267.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAO90459.1 - 1.4e-67 227.0 0.0 1.9e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glyco_hydro_31 PF01055.21 GAO90460.1 - 2.3e-95 320.0 10.0 3.3e-95 319.5 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO90460.1 - 8.2e-05 22.3 0.8 0.00024 20.9 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF937 PF06078.6 GAO90462.1 - 0.12 12.6 1.1 0.41 10.8 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) KR PF08659.5 GAO90464.1 - 1.9e-54 184.1 0.0 6.9e-54 182.2 0.0 2.1 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 GAO90464.1 - 1.5e-39 135.6 0.3 1.1e-38 132.7 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 GAO90464.1 - 5.1e-19 68.0 0.0 1.3e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO90464.1 - 6.4e-12 46.4 0.0 1.7e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90464.1 - 2e-05 24.2 1.0 5.6e-05 22.8 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 GAO90464.1 - 0.045 12.9 0.1 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PP-binding PF00550.20 GAO90464.1 - 0.066 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site CBM_1 PF00734.13 GAO90466.1 - 1.4e-12 47.0 10.8 1.4e-12 47.0 7.5 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 GAO90466.1 - 7.5e-11 42.2 1.8 1.1e-10 41.7 1.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SSP160 PF06933.6 GAO90466.1 - 6.1 4.7 31.4 0.015 13.3 10.4 2.6 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 DUF3902 PF13042.1 GAO90467.1 - 0.023 13.9 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Serpulina_VSP PF05540.6 GAO90467.1 - 0.029 13.1 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein CNTF PF01110.12 GAO90467.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor DUF1275 PF06912.6 GAO90468.1 - 5.5e-47 159.6 5.2 6.6e-47 159.3 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 GAO90468.1 - 0.11 11.8 4.8 3.5 7.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GPI2 PF06432.6 GAO90468.1 - 0.32 10.3 2.4 0.69 9.1 0.3 2.0 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase PEP_mutase PF13714.1 GAO90469.1 - 2.8e-46 157.6 0.0 3.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAO90469.1 - 1.2e-22 79.9 0.1 1.7e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.11 GAO90470.1 - 1.7e-33 115.8 52.6 2.6e-33 115.2 33.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 GAO90471.1 - 1.4e-07 31.3 10.1 1.4e-07 31.3 7.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 GAO90473.1 - 2.1e-52 177.7 0.2 3.7e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Transferase PF02458.10 GAO90473.1 - 9.8e-20 70.3 0.0 4.3e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Transferase family DIOX_N PF14226.1 GAO90474.1 - 3.2e-27 95.3 0.0 5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO90474.1 - 8.3e-22 77.3 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FSH1 PF03959.8 GAO90475.1 - 5.9e-31 107.5 0.0 7.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 GAO90475.1 - 1.5e-07 31.0 0.0 6.1e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAO90475.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO90475.1 - 0.00035 20.5 4.1 0.0026 17.6 2.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 GAO90475.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.8 GAO90475.1 - 0.1 12.1 0.5 0.8 9.2 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.21 GAO90476.1 - 6.5e-69 232.2 0.1 1.2e-68 231.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAO90476.1 - 2.1e-30 105.0 0.0 4.2e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAO90476.1 - 4.7e-28 98.4 0.3 1.4e-26 93.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 GAO90476.1 - 5.8e-25 87.6 0.0 9.4e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 GAO90476.1 - 7.7e-15 55.1 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAO90476.1 - 1.6e-14 53.9 0.2 5e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 GAO90476.1 - 7.2e-09 35.4 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90476.1 - 3.3e-08 33.4 0.0 2.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 GAO90476.1 - 7e-08 32.1 0.0 2.9e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 GAO90476.1 - 5.2e-06 26.8 0.0 1.5e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO90476.1 - 1.7e-05 24.0 0.0 3.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAO90476.1 - 3.6e-05 24.3 0.0 0.00015 22.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO90476.1 - 4.2e-05 22.6 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.20 GAO90476.1 - 0.00067 19.6 1.2 0.0019 18.1 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO90476.1 - 0.0067 16.0 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 KR domain NodS PF05401.6 GAO90476.1 - 0.012 14.9 0.1 0.48 9.7 0.0 2.4 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 GAO90476.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Collagen PF01391.13 GAO90476.1 - 0.03 13.8 6.0 0.059 12.9 4.2 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Methyltransf_28 PF02636.12 GAO90476.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polysacc_synt_2 PF02719.10 GAO90476.1 - 0.059 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Parvo_NS1 PF01057.12 GAO90476.1 - 0.49 9.2 0.0 0.91 8.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Focal_AT PF03623.8 GAO90478.1 - 0.036 13.5 1.0 0.074 12.5 0.1 1.9 2 0 0 2 2 2 0 Focal adhesion targeting region DUF948 PF06103.6 GAO90478.1 - 0.078 12.8 2.5 4 7.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DB PF01682.14 GAO90478.1 - 0.13 12.3 0.7 17 5.5 0.0 2.6 3 0 0 3 3 3 0 DB module NPV_P10 PF05531.7 GAO90478.1 - 2.5 8.4 6.7 0.75 10.0 0.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MARVEL PF01284.18 GAO90479.1 - 0.00017 21.4 6.3 0.00023 20.9 4.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Methyltransf_31 PF13847.1 GAO90480.1 - 1.3e-16 60.5 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90480.1 - 1.5e-16 60.6 0.0 1.5e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90480.1 - 1.9e-16 60.2 0.0 3.7e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90480.1 - 7.3e-13 49.0 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90480.1 - 2e-11 44.2 0.0 6e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90480.1 - 1.6e-09 38.0 0.0 3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90480.1 - 5.1e-07 29.7 0.0 2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO90480.1 - 8.9e-07 28.2 0.0 2.5e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAO90480.1 - 3.3e-05 23.3 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 GAO90480.1 - 0.00058 19.0 0.0 0.00077 18.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 GAO90480.1 - 0.00094 17.9 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 GAO90480.1 - 0.0036 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 GAO90480.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 GAO90480.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 GAO90480.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 GAO90480.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Acetyltransf_3 PF13302.1 GAO90481.1 - 6.6e-12 45.7 0.0 8.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO90481.1 - 1.5e-05 24.9 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAO90481.1 - 0.049 13.5 0.0 0.19 11.6 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain GST_N_3 PF13417.1 GAO90483.1 - 5.1e-18 65.0 0.0 8.8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO90483.1 - 8.9e-15 54.4 0.0 1.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO90483.1 - 4e-11 42.9 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 GAO90483.1 - 2.2e-05 24.3 0.0 5.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin SAICAR_synt PF01259.13 GAO90483.1 - 0.081 12.0 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 SAICAR synthetase Lipase_GDSL_2 PF13472.1 GAO90485.1 - 1e-09 38.7 0.6 1.8e-09 38.0 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO90485.1 - 2e-06 27.7 9.3 1.6e-05 24.8 6.5 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAO90485.1 - 0.02 14.6 0.6 0.067 12.9 0.4 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.2 GAO90486.1 - 1.6e-150 489.9 44.2 1.7e-18 66.7 0.1 15.1 5 3 11 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.25 GAO90486.1 - 3.5e-133 427.3 18.0 6.3e-08 32.0 0.0 26.6 24 4 2 26 26 26 23 Ankyrin repeat Ank_4 PF13637.1 GAO90486.1 - 5.5e-113 367.5 18.1 9.2e-12 45.1 0.0 19.0 9 5 14 23 23 23 21 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO90486.1 - 2.4e-99 323.1 25.3 2.6e-09 37.0 0.0 19.4 10 5 9 20 20 20 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO90486.1 - 1.2e-92 294.4 22.0 7.3e-05 22.6 0.0 26.4 26 1 1 27 27 27 20 Ankyrin repeat HET PF06985.6 GAO90486.1 - 7.3e-10 39.1 1.1 6e-08 32.9 0.7 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3447 PF11929.3 GAO90486.1 - 0.0014 18.4 0.0 54 3.6 0.0 5.9 7 1 0 7 7 7 0 Domain of unknown function (DUF3447) Acetyltransf_3 PF13302.1 GAO90487.1 - 5.1e-32 110.9 0.0 6.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAO90487.1 - 0.0035 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Tub_2 PF04525.7 GAO90488.1 - 0.0033 16.8 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Tubby C 2 Lipase_GDSL PF00657.17 GAO90489.1 - 1.2e-18 67.8 0.5 1.6e-18 67.4 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_20 PF00728.17 GAO90490.1 - 1.5e-37 129.5 0.6 9.3e-37 126.9 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 GAO90490.1 - 5.6e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF1680 PF07944.7 GAO90491.1 - 1.7e-23 82.7 0.0 8.1e-23 80.4 0.0 1.8 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 GAO90491.1 - 0.017 15.1 0.0 0.078 13.0 0.0 2.1 3 0 0 3 3 3 0 Prenyltransferase-like Aminotran_1_2 PF00155.16 GAO90493.1 - 2.9e-35 121.9 0.0 3.4e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAO90493.1 - 7.9e-06 25.1 0.1 4.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAO90493.1 - 1.7e-05 24.0 0.0 3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAO90493.1 - 4.9e-05 21.7 0.0 6.8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 GAO90493.1 - 9e-05 21.4 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-III Aminotran_5 PF00266.14 GAO90493.1 - 0.00041 19.1 0.0 0.0016 17.2 0.0 1.9 2 1 1 3 3 3 1 Aminotransferase class-V OKR_DC_1 PF01276.15 GAO90493.1 - 0.013 14.1 0.1 0.29 9.6 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain SHMT PF00464.14 GAO90493.1 - 0.017 13.5 0.0 0.028 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Acyl_transf_1 PF00698.16 GAO90494.1 - 1.5e-70 238.0 0.9 2.5e-70 237.3 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 GAO90494.1 - 8.5e-68 228.5 0.8 9.5e-67 225.1 0.2 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAO90494.1 - 7.7e-60 202.5 0.0 1.3e-59 201.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAO90494.1 - 4.3e-57 192.6 1.5 1.5e-56 190.9 1.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAO90494.1 - 4e-42 143.9 0.4 4e-42 143.9 0.3 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAO90494.1 - 4.3e-33 113.6 0.2 1.6e-32 111.8 0.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PhyH PF05721.8 GAO90494.1 - 3.2e-26 92.6 0.0 1.9e-25 90.1 0.0 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.21 GAO90494.1 - 7.3e-15 54.6 0.0 2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAO90494.1 - 2.1e-07 30.6 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAO90494.1 - 9.5e-07 28.5 0.1 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 GAO90494.1 - 1.1e-06 28.4 0.0 4.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAO90494.1 - 1.9e-06 28.7 0.0 1.1e-05 26.2 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAO90494.1 - 8.3e-06 26.2 0.0 3.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAO90494.1 - 1.7e-05 24.9 0.1 6e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 GAO90494.1 - 0.00063 20.3 0.0 0.002 18.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAO90494.1 - 0.0012 17.9 0.4 0.0032 16.4 0.3 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 GAO90495.1 - 6e-33 114.0 53.7 1.9e-32 112.3 36.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAO90495.1 - 1.1e-22 80.0 18.3 1.4e-22 79.6 12.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAO90495.1 - 1.9e-11 43.2 10.2 1.9e-11 43.2 7.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Transferase PF02458.10 GAO90496.1 - 6e-07 28.2 0.0 9.8e-06 24.2 0.0 2.1 1 1 0 1 1 1 1 Transferase family adh_short PF00106.20 GAO90497.1 - 1.9e-20 73.4 0.2 4e-20 72.3 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAO90497.1 - 1.8e-09 37.5 0.1 3.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 GAO90497.1 - 7.3e-06 26.1 0.4 1.8e-05 24.7 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAO90497.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAO90497.1 - 0.0019 17.6 0.1 0.0025 17.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAO90497.1 - 0.0031 16.6 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAO90497.1 - 0.019 15.3 0.2 0.055 13.9 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAO90497.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.14 GAO90497.1 - 0.035 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.18 GAO90497.1 - 0.043 13.5 0.1 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAO90497.1 - 0.044 13.4 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO90497.1 - 0.066 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 GAO90497.1 - 0.12 12.8 0.1 0.62 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAO90498.1 - 4e-13 48.8 0.4 6.7e-13 48.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 GAO90499.1 - 1.5e-73 247.9 0.0 1.8e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 GAO90500.1 - 2.6e-16 59.7 0.0 4e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAO90500.1 - 3.2e-10 40.2 0.0 5.9e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAO90500.1 - 6.7e-08 31.5 0.0 3.7e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAO90500.1 - 7.2e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 GAO90500.1 - 8.3e-06 25.2 0.0 0.00012 21.4 0.0 2.3 2 1 1 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.7 GAO90500.1 - 0.00079 18.4 0.0 0.86 8.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RPAP1_N PF08621.5 GAO90501.1 - 0.24 10.9 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal Glyco_hydro_76 PF03663.9 GAO90504.1 - 8.8e-53 179.9 13.6 2.6e-52 178.4 9.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 HATPase_c PF02518.21 GAO90504.1 - 4.2e-29 100.4 0.0 2.7e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO90504.1 - 5.8e-25 87.4 0.3 1.2e-24 86.4 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAO90504.1 - 2.5e-13 49.7 0.0 6.4e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 GAO90504.1 - 0.22 11.7 11.3 0.29 11.3 0.0 3.3 3 0 0 3 3 3 0 HAMP domain Glyco_hydro_15 PF00723.16 GAO90505.1 - 2.7e-106 355.8 0.8 3.6e-106 355.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAO90505.1 - 2.8e-36 123.0 0.7 9e-36 121.3 0.5 1.9 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 GAO90506.1 - 4.1e-72 243.2 1.8 6.7e-72 242.5 1.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO90506.1 - 5e-35 119.4 0.1 1.8e-34 117.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 GAO90506.1 - 5.8e-34 115.5 0.2 1.4e-33 114.3 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain CBM_25 PF03423.8 GAO90506.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Aldedh PF00171.17 GAO90508.1 - 1.7e-164 547.5 0.2 1.9e-164 547.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAO90508.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FAD_binding_4 PF01565.18 GAO90509.1 - 1.2e-33 115.5 8.2 2.2e-33 114.6 5.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO90509.1 - 4.1e-10 39.4 0.1 8.3e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SKG6 PF08693.5 GAO90510.1 - 0.00043 19.5 1.2 0.0012 18.1 0.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 GAO90510.1 - 0.0023 17.5 0.4 0.0036 16.8 0.3 1.3 1 0 0 1 1 1 1 Podoplanin DUF3681 PF12442.3 GAO90510.1 - 0.018 15.1 1.7 0.052 13.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DUF4536 PF15055.1 GAO90510.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DIOX_N PF14226.1 GAO90511.1 - 2.2e-27 95.9 0.0 4e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAO90511.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 GAO90512.1 - 4.5e-30 103.8 9.5 3.1e-09 37.0 0.6 9.5 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAO90512.1 - 1.4e-19 68.8 14.7 0.0001 21.9 0.0 15.0 18 3 0 18 18 17 2 Ankyrin repeat PNP_UDP_1 PF01048.15 GAO90512.1 - 9.8e-13 47.6 0.0 2.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_5 PF13857.1 GAO90512.1 - 2.4e-12 46.6 0.1 2.1e-05 24.5 0.1 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAO90512.1 - 3.5e-12 46.5 0.0 5.5e-07 29.9 0.0 5.8 4 1 2 6 6 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAO90512.1 - 4.4e-11 41.9 0.1 0.007 16.5 0.0 7.4 8 0 0 8 8 6 2 Ankyrin repeat AAA_22 PF13401.1 GAO90512.1 - 1.5e-07 31.6 2.6 6.4e-05 23.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAO90512.1 - 4.2e-07 30.1 0.1 0.00021 21.3 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAO90512.1 - 4.7e-07 29.5 0.1 5e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 GAO90512.1 - 8e-06 25.9 0.0 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 GAO90512.1 - 0.0049 17.0 0.8 0.087 13.0 0.0 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 GAO90512.1 - 0.032 13.0 1.7 0.75 8.6 0.0 2.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 GAO90512.1 - 0.085 13.6 0.1 0.64 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain Pec_lyase_C PF00544.14 GAO90513.1 - 3.2e-46 157.3 9.3 4.8e-46 156.7 6.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 GAO90513.1 - 0.00035 20.3 14.9 0.0044 16.7 10.2 2.3 1 1 1 2 2 2 2 Right handed beta helix region FAD_binding_3 PF01494.14 GAO90514.1 - 6.1e-10 38.6 0.3 1.6e-09 37.3 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90514.1 - 3.4e-06 26.2 0.7 2.4e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO90514.1 - 2.8e-05 24.0 0.6 0.00012 22.0 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAO90514.1 - 0.0071 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAO90514.1 - 0.0074 16.0 0.1 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAO90514.1 - 0.012 14.2 0.4 0.039 12.5 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 GAO90514.1 - 1.3 7.8 3.9 1.3 7.7 2.3 1.5 1 1 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 GAO90515.1 - 2.9e-42 144.6 20.3 5.1e-36 124.1 11.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAO90515.1 - 0.00014 20.4 15.5 0.00014 20.4 10.7 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.8 GAO90515.1 - 0.00068 17.8 13.0 0.0013 16.9 5.7 2.4 3 0 0 3 3 3 2 Transmembrane secretion effector LacY_symp PF01306.14 GAO90515.1 - 0.0023 16.5 14.1 0.0035 15.9 3.6 2.8 3 0 0 3 3 3 2 LacY proton/sugar symporter DUF4440 PF14534.1 GAO90516.1 - 2.2e-10 40.6 0.0 2.8e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF2914 PF11141.3 GAO90516.1 - 0.014 14.8 0.3 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Pec_lyase_C PF00544.14 GAO90517.1 - 6.8e-23 81.1 5.3 1.4e-22 80.1 3.7 1.5 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_18 PF00704.23 GAO90518.1 - 3.9e-64 217.2 1.3 5.9e-64 216.6 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NUP PF06516.6 GAO90519.1 - 1.2e-131 438.2 0.0 1.7e-131 437.7 0.0 1.2 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) LysM PF01476.15 GAO90519.1 - 2.4e-22 78.5 4.3 1.6e-06 27.8 0.0 7.2 7 0 0 7 7 7 5 LysM domain HTH_28 PF13518.1 GAO90519.1 - 0.11 12.5 0.0 30 4.7 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain COesterase PF00135.23 GAO90520.1 - 1.3e-96 324.4 0.1 2.5e-87 293.8 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90520.1 - 3.8e-08 33.1 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 GAO90520.1 - 0.00083 18.6 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 GAO90520.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_GDSL_2 PF13472.1 GAO90521.1 - 5.6e-17 62.4 0.6 9.6e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAO90521.1 - 1.3e-10 41.4 0.2 7.3e-10 39.0 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase adh_short PF00106.20 GAO90522.1 - 1.6e-18 67.1 0.1 1.3e-15 57.6 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90522.1 - 1.1e-07 31.8 0.0 4.4e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO90522.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO90522.1 - 0.00032 20.1 0.0 0.006 16.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 GAO90522.1 - 0.0076 16.0 0.1 0.073 12.8 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAO90522.1 - 0.021 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAO90522.1 - 0.11 12.4 1.0 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding DUF1776 PF08643.5 GAO90522.1 - 0.14 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 GAO90523.1 - 3.3e-15 56.4 0.3 7.7e-15 55.2 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAO90523.1 - 7e-07 29.4 0.1 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO90523.1 - 1.1e-05 25.2 0.1 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO90523.1 - 0.0002 20.8 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAO90523.1 - 0.0071 16.1 0.1 0.98 9.1 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAO90523.1 - 0.021 14.1 0.1 0.048 12.9 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 GAO90523.1 - 0.059 13.3 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Porphobil_deam PF01379.15 GAO90524.1 - 1.7e-51 174.2 0.0 9.2e-50 168.5 0.0 2.1 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAO90524.1 - 0.00057 19.9 0.1 0.085 12.9 0.1 2.5 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MFS_1 PF07690.11 GAO90525.1 - 1.6e-34 119.2 23.4 1.6e-34 119.2 16.2 1.8 1 1 2 3 3 3 2 Major Facilitator Superfamily SieB PF14163.1 GAO90526.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Superinfection exclusion protein B Coiled-coil_56 PF09813.4 GAO90526.1 - 1 9.4 5.6 0.23 11.4 0.6 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Sigma_reg_N PF13800.1 GAO90527.1 - 0.53 10.3 2.5 0.52 10.3 0.2 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2278 PF10042.4 GAO90528.1 - 9.4e-70 234.5 0.0 1.1e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) COesterase PF00135.23 GAO90529.1 - 2.5e-97 326.8 0.0 6.7e-97 325.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAO90529.1 - 0.00018 21.1 0.9 0.00086 18.9 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1491 PF07372.7 GAO90529.1 - 0.19 11.6 0.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) Methyltransf_25 PF13649.1 GAO90532.1 - 4e-16 59.2 0.0 7.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90532.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90532.1 - 8.6e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90532.1 - 1.4e-13 51.3 0.1 3.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90532.1 - 3.9e-12 46.1 0.0 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90532.1 - 8e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90532.1 - 3.3e-10 40.0 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO90532.1 - 5.9e-10 38.7 0.0 9.2e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 GAO90532.1 - 2e-06 27.1 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 GAO90532.1 - 2.4e-05 23.5 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 GAO90532.1 - 8.6e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_20 PF12147.3 GAO90532.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 GAO90532.1 - 0.00048 19.2 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 GAO90532.1 - 0.0008 18.8 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 GAO90532.1 - 0.0013 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 GAO90532.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase DUF938 PF06080.7 GAO90532.1 - 0.005 16.4 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GidB PF02527.10 GAO90532.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF43 PF01861.11 GAO90532.1 - 0.094 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_15 PF09445.5 GAO90532.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.6 GAO90532.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Glyco_hydro_62 PF03664.8 GAO90533.1 - 2.2e-79 266.3 10.7 3e-79 265.9 7.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 GAO90533.1 - 8e-12 44.6 13.8 2.3e-11 43.1 9.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4376 PF14301.1 GAO90533.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DUF3439 PF11921.3 GAO90533.1 - 5.9 6.6 15.6 19 4.9 10.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_43 PF04616.9 GAO90534.1 - 9.7e-31 106.9 2.0 9.7e-31 106.9 1.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_1 PF00734.13 GAO90534.1 - 3e-13 49.1 13.0 7.6e-13 47.8 9.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain HI0933_like PF03486.9 GAO90535.1 - 1.2e-06 27.2 0.6 1.7e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAO90535.1 - 8.1e-06 25.7 0.1 1.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAO90535.1 - 1.7e-05 24.1 0.8 2.7e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO90535.1 - 7.9e-05 21.6 1.2 0.00011 21.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90535.1 - 0.00066 18.6 0.1 0.00098 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90535.1 - 0.00085 19.2 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO90535.1 - 0.0016 17.4 0.4 0.0047 15.8 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAO90535.1 - 0.0058 17.0 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAO90535.1 - 0.0076 15.3 0.3 0.013 14.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAO90535.1 - 0.022 13.6 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 GAO90535.1 - 0.024 14.1 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAO90535.1 - 0.037 14.0 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAO90535.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 GAO90535.1 - 0.18 10.8 0.3 0.28 10.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_10 PF13460.1 GAO90536.1 - 1.5e-12 47.9 0.1 2e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAO90536.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAO90536.1 - 0.0014 17.9 2.1 0.0039 16.4 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 GAO90536.1 - 0.064 13.5 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAO90536.1 - 0.067 12.0 0.0 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Cupin_2 PF07883.6 GAO90537.1 - 1.5e-08 34.0 0.0 3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAO90537.1 - 0.0094 15.3 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ADH_zinc_N PF00107.21 GAO90538.1 - 1.3e-27 95.8 0.0 2.2e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO90538.1 - 2.7e-19 70.3 0.0 8e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90538.1 - 4.8e-10 39.1 0.6 9.2e-10 38.2 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAO90538.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDPD PF03009.12 GAO90539.1 - 9.9e-38 130.0 0.0 2.2e-37 128.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 GAO90539.1 - 1.8e-09 37.5 0.1 2.8e-06 27.3 0.1 2.7 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family HipA_N PF07805.7 GAO90539.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain LIM PF00412.17 GAO90540.1 - 4.6e-19 68.2 18.6 1.4e-10 41.0 5.0 2.8 3 1 0 3 3 3 2 LIM domain Endonuclease_7 PF02945.10 GAO90540.1 - 2.1 8.0 9.0 0.35 10.6 3.4 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII NAD_binding_5 PF07994.7 GAO90541.1 - 1.2e-113 379.5 0.1 1.4e-113 379.3 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 GAO90541.1 - 6.1e-46 154.8 0.4 1.3e-45 153.8 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PALP PF00291.20 GAO90542.1 - 7e-34 117.4 0.7 8.1e-34 117.2 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.7 GAO90543.1 - 9.8e-28 96.0 1.0 2.5e-27 94.8 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO90543.1 - 3.4e-18 65.4 0.3 6.6e-18 64.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 GAO90543.1 - 0.024 13.6 0.2 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase zf-Tim10_DDP PF02953.10 GAO90544.1 - 7.7e-21 73.1 4.2 9.9e-21 72.8 2.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 GAO90544.1 - 0.0067 15.8 2.4 0.012 15.0 1.7 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) CotJB PF12652.2 GAO90544.1 - 0.14 12.2 0.1 2.8 8.0 0.0 2.0 2 0 0 2 2 2 0 CotJB protein CDC37_N PF03234.9 GAO90544.1 - 0.17 12.2 0.3 0.19 12.0 0.2 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RhoGAP PF00620.22 GAO90545.1 - 5.7e-39 133.1 0.0 8.8e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PIG-F PF06699.6 GAO90546.1 - 7.4e-56 189.1 3.2 1e-55 188.6 2.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4310 PF14187.1 GAO90546.1 - 0.0017 17.8 0.3 0.0041 16.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4310) Gly-zipper_YMGG PF13441.1 GAO90546.1 - 0.026 14.0 3.2 0.094 12.2 2.2 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 GAO90546.1 - 0.071 12.7 4.0 1.2 8.8 1.3 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAO90546.1 - 0.096 12.3 4.0 2 8.1 0.7 2.3 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.4 GAO90546.1 - 1.1 9.4 5.8 10 6.3 2.1 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide AAA_11 PF13086.1 GAO90548.1 - 1.1e-64 218.2 0.6 2.1e-64 217.3 0.2 1.6 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.1 GAO90548.1 - 3.1e-58 196.4 0.0 7.7e-58 195.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO90548.1 - 1.8e-12 46.8 0.1 7e-12 44.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 GAO90548.1 - 1.8e-12 47.2 0.0 2.1e-10 40.5 0.0 2.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAO90548.1 - 3.9e-08 33.0 0.0 0.079 12.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAO90548.1 - 1.8e-06 27.2 1.2 2e-05 23.7 0.8 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 GAO90548.1 - 2.2e-06 27.0 0.0 0.044 13.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 GAO90548.1 - 3e-06 27.1 0.0 7.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAO90548.1 - 1.2e-05 24.8 0.1 0.00015 21.3 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 GAO90548.1 - 1.4e-05 24.5 0.9 5.2e-05 22.7 0.3 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 GAO90548.1 - 2.7e-05 23.7 0.1 0.14 11.5 0.0 3.1 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 GAO90548.1 - 8.9e-05 22.6 0.2 0.005 16.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 GAO90548.1 - 0.00048 19.7 0.0 0.06 12.9 0.0 2.4 1 1 0 1 1 1 1 Helicase Flavi_DEAD PF07652.9 GAO90548.1 - 0.0015 18.2 0.3 0.006 16.3 0.1 2.0 1 1 1 2 2 2 1 Flavivirus DEAD domain IstB_IS21 PF01695.12 GAO90548.1 - 0.005 16.2 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAO90548.1 - 0.0056 16.6 0.1 0.016 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 GAO90548.1 - 0.0059 16.0 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) T2SE PF00437.15 GAO90548.1 - 0.006 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 GAO90548.1 - 0.0065 15.8 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAO90548.1 - 0.0086 16.2 0.2 0.038 14.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 GAO90548.1 - 0.0088 16.1 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 GAO90548.1 - 0.012 15.3 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) 4HB_MCP_1 PF12729.2 GAO90548.1 - 0.015 14.6 0.1 0.034 13.4 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TrwB_AAD_bind PF10412.4 GAO90548.1 - 0.018 13.6 0.0 0.035 12.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 GAO90548.1 - 0.036 13.0 0.0 3.3 6.5 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase cobW PF02492.14 GAO90548.1 - 0.037 13.4 0.3 0.42 10.0 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 GAO90548.1 - 0.046 13.5 0.3 0.26 11.1 0.1 2.2 1 1 1 2 2 2 0 Shikimate kinase FtsK_SpoIIIE PF01580.13 GAO90548.1 - 0.05 13.0 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family CbiA PF01656.18 GAO90548.1 - 0.054 12.8 0.3 0.2 11.0 0.2 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNF2_N PF00176.18 GAO90548.1 - 0.15 10.8 0.2 0.38 9.5 0.2 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain NTPase_1 PF03266.10 GAO90548.1 - 0.32 10.7 3.0 3.6 7.2 0.0 2.9 3 0 0 3 3 3 0 NTPase Pirin PF02678.11 GAO90549.1 - 3.8e-23 81.3 0.2 1.2e-22 79.7 0.2 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 GAO90549.1 - 1.1e-07 31.2 0.7 2.4e-05 23.7 0.1 3.2 3 1 0 3 3 3 2 Cupin domain HhH-GPD PF00730.20 GAO90550.1 - 3.9e-21 75.3 0.0 1.3e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAO90550.1 - 1.4e-07 30.8 0.0 3.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_8 PF14716.1 GAO90550.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain UQ_con PF00179.21 GAO90551.1 - 3.2e-41 140.0 0.0 3.6e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAO90551.1 - 0.00027 20.6 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAO90551.1 - 0.11 12.3 1.1 0.15 11.9 0.7 1.5 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.6 GAO90551.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 DUF572 PF04502.8 GAO90552.1 - 3 6.9 9.4 3.8 6.6 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PBP PF01161.15 GAO90553.1 - 1.8e-19 70.0 0.0 2.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FA_hydroxylase PF04116.8 GAO90554.1 - 2.3e-16 60.1 13.8 2.3e-16 60.1 9.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Hemocyanin_C PF03723.9 GAO90554.1 - 0.14 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Hemocyanin, ig-like domain Glyco_hydro_72 PF03198.9 GAO90555.1 - 1.7e-138 460.9 4.4 2e-138 460.6 3.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 GAO90555.1 - 1.1e-06 28.1 0.1 3.7e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GMC_oxred_N PF00732.14 GAO90556.1 - 6e-32 110.9 0.0 1.8e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO90556.1 - 5.6e-19 68.8 0.1 1.7e-18 67.2 0.1 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAO90556.1 - 7.9e-09 34.8 5.3 1.2e-07 30.9 3.7 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90556.1 - 1.3e-08 34.1 1.3 0.00026 20.0 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90556.1 - 4.8e-07 29.8 0.2 0.00013 21.9 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO90556.1 - 1.6e-06 26.9 1.5 8.2e-06 24.5 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 GAO90556.1 - 9.6e-06 25.5 1.6 2.2e-05 24.3 0.2 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO90556.1 - 0.0001 22.4 0.0 0.19 11.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAO90556.1 - 0.00014 21.0 0.2 0.00035 19.7 0.2 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAO90556.1 - 0.00015 20.9 1.1 0.0033 16.5 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAO90556.1 - 0.0014 17.5 2.1 0.0016 17.4 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAO90556.1 - 0.0046 15.6 0.2 0.0098 14.5 0.2 1.5 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 GAO90556.1 - 0.011 14.7 0.2 0.022 13.6 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 GAO90556.1 - 0.012 15.9 1.7 0.035 14.4 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SH3_9 PF14604.1 GAO90557.1 - 4.9e-23 80.4 0.5 3.6e-11 42.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 GAO90557.1 - 9.1e-22 77.0 1.4 1.5e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAO90557.1 - 7.1e-17 60.5 0.2 1.3e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 GAO90557.1 - 1.3e-14 53.6 6.1 2.5e-14 52.7 4.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 GAO90557.1 - 3.7e-06 26.3 0.1 0.00056 19.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 GAO90557.1 - 0.011 15.8 0.2 0.084 13.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain DUF342 PF03961.8 GAO90557.1 - 0.03 12.7 0.8 0.052 11.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 GAO90557.1 - 0.054 13.3 9.9 0.022 14.5 3.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain C1_2 PF03107.11 GAO90557.1 - 0.2 11.8 7.2 0.32 11.1 5.0 1.4 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 GAO90558.1 - 1.4e-32 112.4 0.2 3.7e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO90558.1 - 1.5e-22 79.1 0.1 2.7e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 GAO90558.1 - 0.0077 15.8 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO90558.1 - 0.0085 15.8 1.2 0.37 10.5 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain GTP_CH_N PF12471.3 GAO90559.1 - 6.6e-89 296.7 0.0 9.7e-89 296.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DHDPS PF00701.17 GAO90559.1 - 1.8e-40 138.3 0.1 3e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GTP_cyclohydro2 PF00925.15 GAO90559.1 - 4.7e-17 61.7 0.0 7.7e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Glyco_hydro_32N PF00251.15 GAO90560.1 - 1.4e-80 270.9 8.6 2e-80 270.4 6.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Peptidase_S28 PF05577.7 GAO90561.1 - 1.3e-43 149.1 6.8 7.6e-32 110.4 0.0 3.0 2 1 1 3 3 3 3 Serine carboxypeptidase S28 DUF2014 PF09427.5 GAO90562.1 - 8.3e-113 375.8 0.1 1.3e-112 375.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 GAO90562.1 - 2.4e-18 65.5 0.3 9.1e-18 63.7 0.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 GAO90562.1 - 0.011 15.6 0.8 0.011 15.6 0.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor Leu_zip PF15294.1 GAO90562.1 - 0.065 12.3 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 Leucine zipper bZIP_2 PF07716.10 GAO90562.1 - 1.1 9.1 6.1 0.59 10.0 1.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Ferric_reduct PF01794.14 GAO90563.1 - 2.1e-18 66.6 7.3 2.1e-18 66.6 5.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAO90563.1 - 3.8e-18 65.8 0.0 1.9e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAO90563.1 - 1.7e-14 53.5 0.0 2.2e-13 50.0 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain FLILHELTA PF10306.4 GAO90563.1 - 0.08 12.9 0.5 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA DUF1673 PF07895.6 GAO90563.1 - 0.14 11.6 6.0 0.37 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) E1-E2_ATPase PF00122.15 GAO90563.1 - 0.33 9.9 1.8 0.71 8.8 1.0 1.7 2 0 0 2 2 2 0 E1-E2 ATPase 2-Hacid_dh_C PF02826.14 GAO90564.1 - 7.4e-41 139.2 0.0 1e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO90564.1 - 1.2e-12 47.3 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 GAO90564.1 - 0.017 15.5 0.2 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ketoacyl-synt PF00109.21 GAO90565.1 - 1.2e-69 234.6 0.0 2.1e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAO90565.1 - 5.1e-56 190.3 0.0 1.8e-55 188.5 0.0 1.9 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAO90565.1 - 5.5e-56 189.0 0.1 1.5e-55 187.6 0.0 1.9 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 GAO90565.1 - 5.4e-46 156.5 0.0 2e-45 154.6 0.0 2.1 2 0 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 GAO90565.1 - 3.3e-45 154.5 0.0 2.1e-44 151.8 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAO90565.1 - 5.7e-38 129.4 0.0 2.8e-37 127.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAO90565.1 - 1.1e-16 61.0 0.0 3.6e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAO90565.1 - 1.1e-15 57.3 0.0 1.3e-14 53.8 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAO90565.1 - 3.5e-12 46.3 0.0 9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAO90565.1 - 8.2e-11 42.9 0.0 5.4e-10 40.2 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAO90565.1 - 3.9e-09 36.2 0.0 1.7e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90565.1 - 5.7e-08 33.3 0.0 5e-07 30.3 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90565.1 - 6.7e-07 29.7 0.0 3.1e-06 27.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAO90565.1 - 7e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 GAO90565.1 - 2.6e-05 23.4 0.0 0.00013 21.1 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 GAO90565.1 - 2.6e-05 24.4 0.0 7.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 GAO90565.1 - 4.6e-05 23.7 0.0 0.00022 21.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain DUF2493 PF10686.4 GAO90565.1 - 0.02 14.4 0.5 0.72 9.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) Thiolase_N PF00108.18 GAO90565.1 - 0.059 12.3 0.2 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain YjeF_N PF03853.10 GAO90565.1 - 0.066 12.8 0.0 1.5 8.4 0.1 2.8 3 0 0 3 3 3 0 YjeF-related protein N-terminus PCMT PF01135.14 GAO90565.1 - 0.13 11.7 0.1 0.44 10.0 0.0 1.9 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FSH1 PF03959.8 GAO90566.1 - 2.9e-21 75.8 0.0 3.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FSH1 PF03959.8 GAO90567.1 - 4.2e-29 101.5 0.0 9.7e-29 100.3 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) E1-E2_ATPase PF00122.15 GAO90568.1 - 3e-61 206.4 9.1 3e-61 206.4 6.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO90568.1 - 7.3e-33 113.6 1.2 7.3e-33 113.6 0.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO90568.1 - 6.7e-29 101.8 1.0 2.8e-24 86.7 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO90568.1 - 4.1e-19 67.7 0.1 1.2e-18 66.2 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAO90568.1 - 1.3e-15 57.1 0.0 2.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAO90568.1 - 1.9e-12 47.7 0.0 4.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAO90568.1 - 8.3e-07 28.8 2.2 1.1e-05 25.1 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 GAO90568.1 - 0.014 14.9 0.8 0.043 13.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) RNase_PH PF01138.16 GAO90569.1 - 0.0065 16.7 0.1 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 GAO90570.1 - 4.9e-69 232.2 0.0 6.7e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase GAF_2 PF13185.1 GAO90571.1 - 7.6e-10 39.4 0.0 1.3e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 GAO90571.1 - 5.7e-07 29.7 0.0 8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 GAO90571.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 GAF domain DUF2930 PF11152.3 GAO90571.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) AA_permease_2 PF13520.1 GAO90572.1 - 3.3e-60 203.8 45.2 4.1e-60 203.5 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAO90572.1 - 3.6e-21 75.0 41.9 5.1e-21 74.5 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_11 PF08241.7 GAO90573.1 - 1.1e-15 57.8 0.0 2.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.19 GAO90573.1 - 6.9e-12 45.2 0.0 2.9e-11 43.2 0.0 2.1 2 0 0 2 2 1 1 Acetyltransferase (GNAT) family Methyltransf_18 PF12847.2 GAO90573.1 - 3.7e-10 40.3 0.0 7.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90573.1 - 1e-09 38.3 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90573.1 - 1.7e-09 37.9 0.0 4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90573.1 - 1.8e-08 34.1 0.0 4.6e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90573.1 - 2.8e-08 34.1 0.0 6.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_10 PF13673.1 GAO90573.1 - 3.9e-06 26.9 0.0 9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAO90573.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO90573.1 - 9.6e-05 22.0 0.0 0.00035 20.2 0.0 2.0 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 GAO90573.1 - 0.00014 21.7 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ubie_methyltran PF01209.13 GAO90573.1 - 0.00057 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 GAO90573.1 - 0.0026 16.6 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Acetyltransf_CG PF14542.1 GAO90573.1 - 0.009 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Methyltransf_26 PF13659.1 GAO90573.1 - 0.048 13.7 0.1 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_9 PF13527.1 GAO90573.1 - 0.052 13.4 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Endonuc-BglII PF09195.6 GAO90573.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII NodS PF05401.6 GAO90573.1 - 0.12 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 GAO90573.1 - 0.17 10.8 0.0 8.4 5.3 0.0 2.3 2 1 0 2 2 2 0 Ribosomal RNA adenine dimethylase adh_short PF00106.20 GAO90574.1 - 8.1e-37 126.7 3.0 1e-36 126.3 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90574.1 - 9.5e-21 74.6 0.2 1.1e-20 74.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO90574.1 - 3.5e-14 52.8 1.5 4.8e-14 52.4 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO90574.1 - 3.1e-06 26.7 0.1 4.6e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAO90574.1 - 1.3e-05 24.9 0.2 2.3e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAO90574.1 - 0.00023 19.9 0.1 0.0003 19.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAO90574.1 - 0.00038 20.4 0.1 0.0007 19.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 GAO90574.1 - 0.00046 20.5 0.2 0.00096 19.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 GAO90574.1 - 0.0028 16.7 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 GAO90574.1 - 0.0037 17.1 0.1 0.0074 16.1 0.1 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.10 GAO90574.1 - 0.0043 15.9 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAO90574.1 - 0.0062 16.2 0.7 0.022 14.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAO90574.1 - 0.0087 16.0 0.3 0.0087 16.0 0.2 1.8 2 1 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAO90574.1 - 0.009 15.5 0.2 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Urocanase PF01175.13 GAO90574.1 - 0.009 14.1 0.1 0.013 13.6 0.1 1.2 1 0 0 1 1 1 1 Urocanase 2-Hacid_dh_C PF02826.14 GAO90574.1 - 0.01 15.0 0.1 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAO90574.1 - 0.013 14.3 0.1 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 GAO90574.1 - 0.027 14.5 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAO90574.1 - 0.033 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CVNH PF08881.5 GAO90575.1 - 2.5e-31 107.9 0.2 2.8e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 CVNH domain Aldo_ket_red PF00248.16 GAO90576.1 - 8.3e-72 241.3 0.0 9.4e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Anp1 PF03452.9 GAO90578.1 - 1.6e-109 365.2 0.0 2.3e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Mito_carr PF00153.22 GAO90578.1 - 6.9e-57 189.1 0.5 2.6e-19 68.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_2 PF00535.21 GAO90578.1 - 0.24 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Zip PF02535.17 GAO90579.1 - 2.3e-61 207.5 9.6 4.9e-60 203.1 6.6 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.5 GAO90580.1 - 6.2e-61 205.2 11.8 7.5e-61 205.0 8.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran PF00005.22 GAO90582.1 - 3.9e-47 160.0 0.0 1.2e-28 100.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAO90582.1 - 5.8e-28 98.0 19.7 9.7e-16 57.9 7.3 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAO90582.1 - 2.3e-12 46.6 3.8 7.2e-06 25.3 0.5 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAO90582.1 - 9.7e-08 32.2 4.3 0.0019 18.2 0.1 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 GAO90582.1 - 6.1e-07 29.6 0.4 0.011 15.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAO90582.1 - 8.1e-07 29.2 1.7 3.2 7.6 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 GAO90582.1 - 1.5e-06 27.6 2.7 0.00057 19.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAO90582.1 - 1.9e-06 27.4 0.1 0.0061 15.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 GAO90582.1 - 2.9e-06 26.4 1.8 0.029 13.2 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.1 GAO90582.1 - 4.2e-06 27.2 0.5 0.042 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAO90582.1 - 0.00016 21.3 0.1 0.37 10.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 GAO90582.1 - 0.00017 22.0 0.1 0.21 12.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 GAO90582.1 - 0.00023 20.4 0.1 0.69 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 GAO90582.1 - 0.0022 17.6 3.2 0.11 12.2 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 GAO90582.1 - 0.0025 17.2 1.2 0.3 10.5 0.2 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 GAO90582.1 - 0.003 17.0 1.9 1.5 8.2 0.0 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 GAO90582.1 - 0.0033 17.7 0.1 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAO90582.1 - 0.0043 17.0 0.0 0.69 9.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 GAO90582.1 - 0.0043 15.7 1.1 0.34 9.4 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 GAO90582.1 - 0.0057 16.5 0.1 4.5 7.2 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 GAO90582.1 - 0.0063 16.3 3.4 0.0069 16.2 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_30 PF13604.1 GAO90582.1 - 0.01 15.4 2.5 5.1 6.6 0.2 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAO90582.1 - 0.01 16.0 0.0 3.3 7.9 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 GAO90582.1 - 0.012 14.0 0.2 1.2 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 GAO90582.1 - 0.014 16.2 0.1 0.98 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAO90582.1 - 0.019 14.3 1.0 0.57 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 GAO90582.1 - 0.021 14.5 1.7 0.42 10.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAO90582.1 - 0.033 13.6 2.0 0.76 9.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF2075 PF09848.4 GAO90582.1 - 0.04 12.8 1.5 1.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 GAO90582.1 - 0.052 13.0 0.3 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 GAO90582.1 - 0.053 13.3 0.0 13 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAO90582.1 - 0.069 12.8 0.1 3.6 7.2 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase Imm25 PF15571.1 GAO90582.1 - 0.088 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 25 RNA_helicase PF00910.17 GAO90582.1 - 0.094 12.8 0.0 26 5.0 0.0 3.2 3 0 0 3 3 3 0 RNA helicase CbiA PF01656.18 GAO90582.1 - 0.14 11.5 1.3 4.9 6.4 0.0 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.1 GAO90582.1 - 0.15 11.5 0.1 3.3 7.2 0.0 2.6 2 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 GAO90582.1 - 0.16 11.0 0.8 0.66 9.1 0.0 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 GAO90582.1 - 0.23 11.1 2.1 6.4 6.4 0.1 2.6 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.4 GAO90582.1 - 3.1 6.2 5.3 8 4.9 0.4 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Pex24p PF06398.6 GAO90583.1 - 1.2e-91 307.1 0.0 1.5e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 GAO90583.1 - 0.032 12.1 1.4 0.052 11.4 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) DUF639 PF04842.7 GAO90583.1 - 0.069 11.3 0.3 0.11 10.6 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Pkinase PF00069.20 GAO90584.1 - 1.6e-58 197.8 0.0 2.5e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90584.1 - 6.5e-21 74.5 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAO90584.1 - 0.061 13.0 0.0 0.46 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAO90584.1 - 0.07 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAO90584.1 - 0.19 10.4 0.2 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase COPIIcoated_ERV PF07970.7 GAO90585.1 - 1.2e-32 113.3 0.6 6.8e-32 110.8 0.4 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAO90585.1 - 1.5e-17 63.3 0.0 3.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Filament PF00038.16 GAO90586.1 - 3.2e-06 26.8 23.4 3.2e-06 26.8 16.2 4.1 4 1 1 5 5 5 2 Intermediate filament protein TPR_MLP1_2 PF07926.7 GAO90586.1 - 0.0029 17.3 69.5 0.0081 15.9 10.2 4.6 4 0 0 4 4 4 3 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 GAO90586.1 - 0.013 15.4 21.1 0.013 15.4 14.6 6.4 6 2 1 7 7 7 0 Domain of unknown function (DUF4200) Maf1 PF09174.5 GAO90587.1 - 8.7e-65 217.9 0.0 1.4e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 GAO90587.1 - 3.6e-52 175.8 1.7 5.2e-52 175.3 1.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3969 PF13108.1 GAO90587.1 - 0.073 12.7 2.0 0.96 9.1 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3969) FAD_binding_3 PF01494.14 GAO90588.1 - 7.1e-93 311.4 0.0 8.8e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAO90588.1 - 5.5e-63 211.5 0.0 1.1e-62 210.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 GAO90588.1 - 0.00096 17.7 0.0 0.0015 17.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 GAO90588.1 - 0.0015 17.5 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAO90588.1 - 0.0015 17.6 0.0 0.0097 15.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAO90588.1 - 0.0028 16.5 0.0 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO90588.1 - 0.0034 17.3 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO90588.1 - 0.0035 16.2 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90588.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO90588.1 - 0.0048 17.2 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAO90588.1 - 0.0056 15.5 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase XdhC_C PF13478.1 GAO90588.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_oxidored PF12831.2 GAO90588.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MARVEL PF01284.18 GAO90589.1 - 1.6e-28 99.3 11.3 1.8e-28 99.1 7.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain Terpene_synth_C PF03936.11 GAO90590.1 - 3.1e-14 52.8 0.0 4.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Transglut_core PF01841.14 GAO90590.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF2236 PF09995.4 GAO90591.1 - 5.7e-32 110.9 0.1 8.2e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Metallophos PF00149.23 GAO90592.1 - 3.3e-05 23.3 5.6 0.0016 17.9 4.2 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase PA_decarbox PF05870.6 GAO90593.1 - 4.2e-08 32.8 0.1 5e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) PRELI PF04707.9 GAO90596.1 - 1.4e-23 83.2 0.0 4.3e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.20 GAO90597.1 - 1.5e-12 47.2 0.1 2.5e-09 36.6 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.14 GAO90598.1 - 9.2e-50 169.2 0.0 1.2e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 GAO90599.1 - 2e-49 165.0 25.2 7.6e-12 44.7 0.3 7.9 3 2 5 9 9 9 9 TPR repeat TPR_1 PF00515.23 GAO90599.1 - 3.7e-41 137.0 23.7 5.2e-07 29.0 0.0 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAO90599.1 - 6.5e-39 128.7 25.7 4.9e-06 26.0 0.1 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAO90599.1 - 3e-23 81.5 28.1 1.5e-07 31.2 0.6 7.6 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAO90599.1 - 9.5e-23 80.3 24.8 5.9e-07 29.9 0.6 7.3 5 2 4 9 9 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAO90599.1 - 6.4e-17 60.2 11.7 0.038 14.1 0.0 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO90599.1 - 1.5e-16 58.8 21.7 0.0034 17.0 0.1 9.6 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAO90599.1 - 2.3e-15 56.1 9.3 9e-07 28.6 0.1 6.5 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAO90599.1 - 1.1e-14 53.5 17.8 0.04 14.5 0.1 9.9 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAO90599.1 - 2.1e-13 48.9 16.1 0.025 14.3 0.1 8.9 7 1 1 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 GAO90599.1 - 4.9e-12 45.8 16.5 0.0044 17.1 0.2 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAO90599.1 - 4.5e-10 39.7 22.1 2.3e-05 24.6 0.4 7.1 6 1 3 9 9 9 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAO90599.1 - 6.4e-06 25.3 8.6 0.46 9.7 0.0 6.2 6 0 0 6 6 6 2 SHNi-TPR MAS20 PF02064.10 GAO90599.1 - 0.00066 19.5 4.9 1 9.2 0.2 4.4 4 1 1 5 5 5 1 MAS20 protein import receptor TPR_6 PF13174.1 GAO90599.1 - 0.0037 17.6 26.2 3.3 8.3 0.5 8.9 11 0 0 11 11 7 1 Tetratricopeptide repeat Ycf1 PF05758.7 GAO90599.1 - 0.011 13.5 0.6 0.014 13.1 0.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 GAO90599.1 - 0.027 13.8 6.7 0.048 13.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2561 PF10812.3 GAO90599.1 - 0.066 12.8 1.9 0.12 11.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TPR_10 PF13374.1 GAO90599.1 - 0.072 13.0 11.1 2.5 8.1 0.3 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RR_TM4-6 PF06459.7 GAO90599.1 - 0.19 11.5 7.4 0.36 10.6 5.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sel1 PF08238.7 GAO90599.1 - 0.29 11.8 7.1 0.86 10.3 0.1 4.5 5 0 0 5 5 3 0 Sel1 repeat PcfK PF14058.1 GAO90599.1 - 0.6 10.2 10.9 0.26 11.4 5.3 2.0 2 0 0 2 2 2 0 PcfK-like protein NARP1 PF12569.3 GAO90599.1 - 0.69 8.5 29.2 0.73 8.5 1.3 4.7 2 1 1 4 4 4 0 NMDA receptor-regulated protein 1 FHA PF00498.21 GAO90600.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Fungal_trans PF04082.13 GAO90602.1 - 8.7e-09 34.6 1.8 2.6e-08 33.0 1.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAO90602.1 - 8.5e-05 22.6 2.4 8.5e-05 22.6 1.6 3.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAO90602.1 - 0.00077 19.2 0.8 0.00077 19.2 0.5 2.5 3 0 0 3 3 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAO90602.1 - 0.00081 19.5 14.3 0.11 12.8 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAO90602.1 - 0.0015 18.7 11.1 0.012 15.8 2.6 4.8 5 1 0 5 5 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 GAO90602.1 - 0.049 13.8 0.2 0.049 13.8 0.2 3.2 4 0 0 4 4 2 0 C2H2-type zinc-finger domain Zn_clus PF00172.13 GAO90602.1 - 0.06 13.2 1.2 0.06 13.2 0.8 3.1 4 0 0 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 GAO90602.1 - 0.21 11.8 0.3 0.21 11.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO90602.1 - 0.29 11.4 4.2 0.38 11.0 0.1 2.9 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAO90602.1 - 1.1 9.4 5.8 0.21 11.7 0.2 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RseC_MucC PF04246.7 GAO90602.1 - 1.5 8.4 8.4 4.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ADH_zinc_N PF00107.21 GAO90603.1 - 6.9e-32 109.7 0.3 1e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAO90603.1 - 5.8e-23 82.1 0.1 1.1e-22 81.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90603.1 - 1e-12 47.7 0.0 2.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAO90603.1 - 0.00055 19.5 0.1 0.0012 18.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 GAO90603.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAO90603.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CMAS PF02353.15 GAO90603.1 - 0.095 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FAD_binding_3 PF01494.14 GAO90604.1 - 5e-21 75.1 0.0 8.5e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAO90604.1 - 2e-09 36.8 0.4 4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAO90604.1 - 0.00043 20.2 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAO90604.1 - 0.00048 18.7 2.3 0.16 10.4 1.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 GAO90604.1 - 0.00075 18.4 6.6 0.001 18.0 3.7 1.8 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 GAO90604.1 - 0.00086 18.2 0.0 0.0031 16.3 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 GAO90604.1 - 0.0012 18.8 0.4 0.0031 17.5 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO90604.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO90604.1 - 0.0017 18.6 2.0 1 9.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAO90604.1 - 0.0019 17.3 0.0 0.0052 15.9 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 GAO90604.1 - 0.043 12.4 0.2 0.11 11.0 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 GAO90604.1 - 0.072 12.1 4.3 0.13 11.3 3.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAO90604.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAO90604.1 - 0.39 9.5 2.3 0.64 8.8 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3500 PF12006.3 GAO90605.1 - 3e-108 361.4 0.0 3.6e-108 361.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Pkinase PF00069.20 GAO90606.1 - 9.2e-74 247.8 0.0 1.4e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90606.1 - 1.1e-36 126.2 0.0 1.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 GAO90606.1 - 4.5e-09 36.3 0.0 8.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 GAO90606.1 - 3.9e-06 26.0 0.1 1.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAO90606.1 - 2.9e-05 23.4 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 GAO90606.1 - 0.004 15.7 0.1 0.0061 15.1 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 GAO90606.1 - 0.017 14.1 0.7 0.072 12.1 0.1 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAO90606.1 - 0.034 13.8 3.1 0.053 13.2 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAO90606.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 GAO90606.1 - 0.15 11.6 0.1 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 GAO90606.1 - 0.2 10.4 0.3 0.31 9.8 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sulfate_transp PF00916.15 GAO90610.1 - 0.00011 21.3 4.5 0.00011 21.3 3.1 3.3 2 1 1 3 3 3 1 Sulfate transporter family Peptidase_M24 PF00557.19 GAO90611.1 - 1.9e-44 151.7 0.1 2.5e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT6_acidic PF14632.1 GAO90611.1 - 0.012 15.7 4.6 0.033 14.3 3.2 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 ERF PF04404.7 GAO90611.1 - 3.3 7.2 8.0 2.6 7.5 3.4 2.2 2 0 0 2 2 2 0 ERF superfamily AAA_16 PF13191.1 GAO90612.1 - 9e-11 42.0 0.2 3.2e-08 33.7 0.1 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAO90612.1 - 3.5e-05 23.9 0.1 0.00037 20.6 0.0 2.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAO90612.1 - 0.0015 18.2 0.1 0.01 15.4 0.0 2.7 2 1 0 2 2 2 1 NACHT domain TPR_12 PF13424.1 GAO90612.1 - 0.0038 17.1 27.5 0.62 10.0 0.0 9.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAO90612.1 - 0.017 15.0 9.4 4.2 7.5 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_19 PF13245.1 GAO90612.1 - 0.092 12.5 1.5 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain F-box PF00646.28 GAO90613.1 - 0.0017 17.9 0.3 0.013 15.1 0.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 GAO90613.1 - 0.0074 15.9 2.6 0.034 13.8 0.4 2.9 3 0 0 3 3 3 1 F-box-like p450 PF00067.17 GAO90614.1 - 1e-06 27.5 0.0 1.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAO90615.1 - 2.4e-07 30.5 13.6 2.4e-07 30.5 9.5 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.6 GAO90615.1 - 0.57 9.8 0.0 0.57 9.8 0.0 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain WI12 PF07107.6 GAO90616.1 - 0.073 12.9 2.2 0.11 12.4 1.5 1.4 1 1 0 1 1 1 0 Wound-induced protein WI12 DUF126 PF01989.11 GAO90616.1 - 0.22 11.2 2.0 0.34 10.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF126 PTP_N PF12453.3 GAO90616.1 - 8.8 6.0 19.6 1.6 8.3 0.7 3.8 3 1 0 3 3 3 0 Protein tyrosine phosphatase N terminal MBOAT_2 PF13813.1 GAO90617.1 - 3.6e-20 71.8 3.0 4.4e-19 68.3 2.3 2.7 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 GAO90618.1 - 3.2e-33 114.9 60.1 6.1e-23 81.1 14.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90618.1 - 4.1e-10 38.8 10.4 4.1e-10 38.8 7.2 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 GAO90619.1 - 1e-13 50.6 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 GAO90620.1 - 2.1e-58 197.8 0.0 2.7e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO90620.1 - 2.3e-35 121.9 0.0 4.3e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAO90620.1 - 0.00086 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAO90620.1 - 0.0097 14.8 0.0 0.024 13.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO90620.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAO90620.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UTP15_C PF09384.5 GAO90621.1 - 2.1e-55 186.5 1.0 2.1e-55 186.5 0.7 1.9 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 GAO90621.1 - 1.4e-26 91.3 1.0 5.4e-07 29.2 0.3 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 GAO90621.1 - 0.026 13.5 1.4 0.84 8.5 0.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.1 GAO90621.1 - 2.3 8.6 9.2 18 5.7 0.7 4.4 5 0 0 5 5 5 0 PQQ-like domain L31 PF09784.4 GAO90621.1 - 2.7 8.1 6.0 2.4 8.2 2.3 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Prenyltransf PF01255.14 GAO90623.1 - 1.4e-68 230.3 0.0 1.7e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase C2 PF00168.25 GAO90624.1 - 5.7e-11 42.1 0.0 9.6e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ribosomal_S18 PF01084.15 GAO90624.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 L_HGMIC_fpl PF10242.4 GAO90626.1 - 0.00015 21.7 5.8 0.00032 20.7 4.0 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 GAO90626.1 - 0.0011 18.5 8.0 0.0018 17.9 5.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ABC2_membrane PF01061.19 GAO90626.1 - 0.03 13.4 3.0 0.16 11.1 0.6 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Claudin_2 PF13903.1 GAO90626.1 - 0.038 13.6 9.6 0.05 13.3 5.7 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 GAO90626.1 - 0.078 12.6 11.5 0.35 10.5 8.0 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4405 PF14358.1 GAO90626.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) Clc-like PF07062.7 GAO90626.1 - 0.85 8.8 9.7 1.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Clc-like RRM_1 PF00076.17 GAO90627.1 - 2.9e-51 170.9 0.0 1.9e-16 59.4 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90627.1 - 8.4e-44 147.4 0.0 3.7e-14 52.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO90627.1 - 5.7e-27 93.3 0.0 2.2e-09 37.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAO90627.1 - 5.6e-10 38.8 0.1 0.00015 21.4 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 GAO90627.1 - 0.0054 16.1 0.2 0.016 14.5 0.1 1.8 1 0 0 1 1 1 1 Lsm interaction motif Ribosomal_L22 PF00237.14 GAO90628.1 - 9.4e-16 57.6 0.1 3.8e-14 52.5 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.17 GAO90629.1 - 1.5e-17 64.0 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PhyH PF05721.8 GAO90630.1 - 1e-42 146.5 0.0 1.4e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UPF0546 PF10639.4 GAO90631.1 - 2.1e-36 124.1 0.6 4.5e-29 100.5 0.3 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 DUF1510 PF07423.6 GAO90631.1 - 0.0026 17.1 0.7 0.0032 16.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ctr PF04145.10 GAO90631.1 - 0.036 14.0 0.1 0.23 11.4 0.1 2.0 1 1 0 1 1 1 0 Ctr copper transporter family EamA PF00892.15 GAO90631.1 - 0.13 12.2 4.6 0.11 12.5 1.2 2.1 2 1 0 2 2 2 0 EamA-like transporter family DUF3449 PF11931.3 GAO90631.1 - 0.3 10.5 4.0 0.42 10.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Hid1 PF12722.2 GAO90631.1 - 0.88 7.1 4.1 1.1 6.8 2.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EmrE PF13536.1 GAO90631.1 - 1.5 9.0 6.2 0.1 12.7 0.5 1.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF751 PF05421.6 GAO90631.1 - 1.7 9.0 5.2 2 8.7 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF751) CobT PF06213.7 GAO90631.1 - 1.8 7.6 8.8 2.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MCPVI PF02993.9 GAO90631.1 - 9.3 6.3 9.6 13 5.8 6.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Chitin_synth_1 PF01644.12 GAO90632.1 - 9.6e-81 269.3 0.1 1.5e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAO90632.1 - 1.4e-30 104.7 0.0 2.6e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAO90632.1 - 7e-22 77.5 1.6 3.9e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 GAO90632.1 - 1e-07 32.0 0.0 4.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAO90632.1 - 3e-07 30.3 8.5 3e-07 30.3 5.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 LMWPc PF01451.16 GAO90633.1 - 5.1e-30 104.5 0.0 4.7e-28 98.2 0.0 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 GAO90634.1 - 7.3e-63 211.1 0.2 8.8e-63 210.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 GAO90634.1 - 3.3e-06 27.4 0.2 8.4e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Rubrerythrin SPT2 PF08243.6 GAO90634.1 - 0.11 12.8 4.1 0.21 11.9 2.9 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.13 GAO90635.1 - 4.7e-34 116.6 0.0 7.7e-33 112.7 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.5 GAO90636.1 - 1.5e-42 145.3 16.9 1.5e-42 145.3 11.7 7.4 6 1 1 7 7 7 1 MRC1-like domain KR PF08659.5 GAO90636.1 - 0.29 10.7 4.0 0.27 10.8 1.1 2.2 2 0 0 2 2 2 0 KR domain tRNA-synt_1c PF00749.16 GAO90637.1 - 3.4e-95 318.3 0.0 4.2e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAO90637.1 - 3.2e-31 108.3 0.0 9.7e-31 106.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain HAD_2 PF13419.1 GAO90638.1 - 2.7e-08 34.2 0.0 0.0015 18.7 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO90638.1 - 4.5e-07 29.4 0.3 2.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like FAD_binding_3 PF01494.14 GAO90640.1 - 4.4e-17 62.1 0.1 2.7e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO90640.1 - 1.4e-07 31.4 0.3 3.3e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAO90640.1 - 5.6e-05 22.1 3.2 0.0026 16.6 1.1 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 GAO90640.1 - 0.00073 19.8 0.2 0.0018 18.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO90640.1 - 0.0011 18.8 0.2 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAO90640.1 - 0.0023 16.8 3.1 0.0038 16.1 0.6 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO90640.1 - 0.0061 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 GAO90640.1 - 0.0098 15.7 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.9 GAO90640.1 - 0.038 12.6 0.4 0.058 12.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAO90640.1 - 0.061 13.0 0.4 0.18 11.5 0.3 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 GAO90640.1 - 0.092 11.5 0.4 0.14 10.9 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAO90640.1 - 0.1 11.0 0.3 0.16 10.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAO90640.1 - 0.11 12.5 0.3 0.19 11.7 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAO90640.1 - 0.14 11.5 0.5 0.4 10.0 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UbiA PF01040.13 GAO90641.1 - 1.7e-23 83.1 12.0 2.4e-23 82.6 8.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family YlaC PF10777.4 GAO90641.1 - 0.41 10.1 2.9 4.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Inner membrane protein YlaC MIF4G PF02854.14 GAO90643.1 - 1.9e-22 79.7 1.4 2e-22 79.6 0.1 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 GAO90643.1 - 2.7e-15 56.0 0.0 1.1e-14 54.0 0.0 2.2 1 0 0 1 1 1 1 MA3 domain SRP14 PF02290.10 GAO90644.1 - 4.9e-29 100.0 0.1 6.5e-29 99.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein CABIT PF12736.2 GAO90644.1 - 0.08 11.9 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, Inp1 PF12634.2 GAO90645.1 - 3e-37 127.5 0.0 5.8e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Ribophorin_II PF05817.9 GAO90645.1 - 0.1 10.8 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II EI24 PF07264.6 GAO90646.1 - 0.00081 18.8 14.0 0.0051 16.2 9.7 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.10 GAO90647.1 - 7.1e-156 518.5 0.0 8.1e-156 518.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DAO PF01266.19 GAO90648.1 - 7.8e-54 182.9 0.0 9.6e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAO90648.1 - 6.4e-08 31.8 0.0 1.3e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO90648.1 - 3.6e-06 26.8 0.2 0.00011 22.1 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 GAO90648.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family GIDA PF01134.17 GAO90648.1 - 0.0009 18.1 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 GAO90648.1 - 0.0019 18.5 0.0 0.0061 16.9 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO90648.1 - 0.003 17.4 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO90648.1 - 0.0035 17.1 0.0 0.058 13.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAO90648.1 - 0.0046 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 GAO90648.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAO90648.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAO90648.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAO90648.1 - 0.041 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAO90648.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 GAO90648.1 - 0.078 12.4 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 GAO90649.1 - 5.5e-22 77.9 23.9 5.5e-22 77.9 16.6 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily HEAT_PBS PF03130.11 GAO90649.1 - 0.13 12.8 1.7 0.21 12.1 0.3 2.0 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Pro_isomerase PF00160.16 GAO90650.1 - 1.7e-49 168.0 0.5 2.7e-49 167.3 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 GAO90650.1 - 6e-14 51.4 6.1 1.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 GAO90650.1 - 1.5e-07 31.2 2.3 1.1e-05 25.2 2.8 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAO90650.1 - 3.1e-07 29.7 6.1 1.7e-06 27.3 0.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAO90650.1 - 3.4e-07 29.6 5.7 2.2e-05 24.0 0.7 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAO90650.1 - 0.00038 20.0 10.7 0.00047 19.7 0.8 4.0 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAO90650.1 - 0.0082 16.7 4.6 0.028 15.0 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAO90650.1 - 0.15 12.7 10.2 0.43 11.3 5.4 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAO90650.1 - 0.27 11.5 5.1 3 8.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAO90650.1 - 0.53 10.8 4.9 0.47 11.0 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 GAO90651.1 - 1.9e-47 160.8 0.0 2.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 GAO90652.1 - 1.5e-97 325.4 16.0 2.3e-97 324.8 11.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 GAO90652.1 - 2.7e-44 150.2 9.6 5.8e-44 149.2 6.7 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 GAO90652.1 - 0.006 16.1 4.1 0.014 14.9 2.8 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 GAO90652.1 - 0.039 13.8 0.1 0.039 13.8 0.1 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 GAO90652.1 - 0.066 13.5 7.2 0.2 12.0 0.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Poty_PP PF08440.5 GAO90652.1 - 0.078 12.0 0.6 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 GAO90652.1 - 2.4 8.2 8.9 0.26 11.3 1.7 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Syntaxin PF00804.20 GAO90652.1 - 5.5 7.2 9.7 0.86 9.8 2.3 2.5 1 1 1 2 2 2 0 Syntaxin zf-C2H2_4 PF13894.1 GAO90653.1 - 4.5e-09 36.0 7.0 1.2e-05 25.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO90653.1 - 9.9e-09 35.0 8.8 5.8e-07 29.4 0.1 2.9 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 GAO90653.1 - 0.074 13.2 2.1 0.85 9.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAO90653.1 - 0.1 12.7 0.2 0.1 12.7 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 GAO90653.1 - 0.26 11.6 0.3 0.26 11.6 0.2 3.4 3 1 0 3 3 3 0 Zinc-finger double domain DNA_binding_1 PF01035.15 GAO90654.1 - 2.8e-26 91.0 0.0 3.6e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pyr_redox_2 PF07992.9 GAO90655.1 - 7.6e-41 140.1 13.2 2.6e-38 131.9 9.2 4.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAO90655.1 - 9.8e-40 135.0 1.5 1.8e-39 134.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 GAO90655.1 - 7e-24 84.0 12.3 6.9e-22 77.6 0.9 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAO90655.1 - 2.7e-10 39.9 0.4 2.7e-10 39.9 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAO90655.1 - 3.9e-10 39.5 4.2 2.5e-05 24.2 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAO90655.1 - 5.3e-10 39.7 1.1 8e-06 26.0 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAO90655.1 - 9.1e-09 34.6 12.5 2.2e-07 30.1 2.7 2.8 2 2 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAO90655.1 - 7.3e-08 31.6 3.4 7.3e-08 31.6 2.4 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAO90655.1 - 3.6e-07 29.4 22.9 0.00039 19.4 1.8 4.0 2 2 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAO90655.1 - 4.4e-07 29.1 1.4 0.007 15.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 GAO90655.1 - 9.7e-07 27.5 15.3 0.00012 20.6 1.3 4.1 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.12 GAO90655.1 - 2.9e-06 26.5 9.0 5.7e-05 22.3 1.0 2.5 1 1 1 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 GAO90655.1 - 2.9e-06 26.9 3.4 0.0018 17.8 0.1 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.14 GAO90655.1 - 0.00084 17.6 0.6 0.28 9.3 0.1 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 GAO90655.1 - 0.00089 18.4 13.9 0.039 13.0 0.9 3.3 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 GAO90655.1 - 0.0021 17.0 1.7 0.068 12.0 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.13 GAO90655.1 - 0.0029 17.3 4.8 0.0081 15.8 1.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAO90655.1 - 0.0069 16.6 1.6 0.18 12.1 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 GAO90655.1 - 0.011 14.8 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF711 PF05167.7 GAO90655.1 - 0.036 12.7 0.0 0.074 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) THF_DHG_CYH_C PF02882.14 GAO90655.1 - 0.055 12.5 1.1 4.4 6.3 0.0 3.5 2 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Trp_halogenase PF04820.9 GAO90655.1 - 0.16 10.5 5.9 0.35 9.4 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 GAO90656.1 - 9.2e-80 268.4 23.9 1.1e-79 268.1 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90656.1 - 7.6e-21 74.2 47.3 7.6e-16 57.7 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAO90656.1 - 3.2 7.8 8.6 4.2 7.4 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) PGM_PMM_I PF02878.11 GAO90657.1 - 5.9e-36 123.0 0.1 1e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAO90657.1 - 4e-23 81.7 0.0 1.3e-22 80.0 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 GAO90657.1 - 1.2e-14 54.3 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 GAO90657.1 - 8.8e-08 32.0 0.0 4.7e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.19 GAO90658.1 - 1.1e-34 120.0 31.6 1.5e-34 119.5 21.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAO90658.1 - 1.2e-10 40.9 0.0 2.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 GAO90659.1 - 4.1e-09 35.7 0.0 1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 GAO90660.1 - 3.7e-28 97.2 0.5 4.5e-28 96.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Tom5 PF10642.4 GAO90661.1 - 0.017 14.7 1.0 0.096 12.3 0.7 2.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase ELYS PF13934.1 GAO90662.1 - 8.3e-79 264.4 0.7 1e-78 264.2 0.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 GAO90663.1 - 1.1e-76 256.9 9.9 3.6e-76 255.2 6.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAO90663.1 - 5.3e-28 97.4 0.1 2.1e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAO90663.1 - 3.6e-12 46.8 6.6 4.3e-05 23.6 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAO90663.1 - 0.0003 20.2 0.0 0.00071 19.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 GAO90663.1 - 0.006 16.4 16.2 0.006 16.4 11.2 7.3 2 2 4 7 7 7 2 Tropomyosin like Reo_sigmaC PF04582.7 GAO90663.1 - 0.29 10.2 33.4 0.021 14.0 1.3 5.2 2 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 GAO90663.1 - 4.3 5.6 111.0 0.73 8.2 4.6 6.5 3 2 4 7 7 7 0 AAA domain Folliculin PF11704.3 GAO90664.1 - 1e-47 161.8 0.0 1.5e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Clp1 PF06807.9 GAO90665.1 - 7.9e-09 35.5 0.0 0.00081 19.2 0.0 2.4 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAO90665.1 - 0.00075 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAO90665.1 - 0.00086 19.2 0.6 0.01 15.7 0.0 3.0 4 1 1 5 5 5 1 AAA domain AAA_17 PF13207.1 GAO90665.1 - 0.0015 19.3 0.0 0.0044 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAO90665.1 - 0.029 13.8 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family adh_short PF00106.20 GAO90665.1 - 0.064 13.1 0.2 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase AAA_22 PF13401.1 GAO90665.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAO90665.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAO90665.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 GAO90665.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 GAO90665.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.6 GAO90666.1 - 1.8e-52 177.9 12.7 1.8e-52 177.9 8.8 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 GRAM PF02893.15 GAO90667.1 - 1.3e-28 98.3 1.4 2.4e-17 62.2 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 GAO90667.1 - 2.1e-24 85.8 0.0 9.2e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 GAO90667.1 - 9.1e-17 61.1 0.1 2.4e-15 56.6 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 GAO90667.1 - 1.4e-07 31.7 0.4 7.5e-07 29.3 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAO90667.1 - 9.5e-05 22.3 0.0 0.00034 20.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 GAO90667.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 GAO90667.1 - 0.00029 19.5 0.0 0.0006 18.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.12 GAO90668.1 - 1.4e-27 95.7 0.1 2.1e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 GAO90668.1 - 0.0005 19.7 0.1 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 GAO90668.1 - 0.015 15.0 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Hr1 repeat DUF4201 PF13870.1 GAO90668.1 - 0.02 14.3 0.6 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Vma12 PF11712.3 GAO90669.1 - 2e-42 144.2 0.0 2.8e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PsbN PF02468.10 GAO90669.1 - 3.8 7.2 5.5 0.66 9.6 0.5 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Amidohydro_1 PF01979.15 GAO90670.1 - 3.3e-21 76.2 0.2 1.6e-18 67.4 0.1 3.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAO90670.1 - 2.3e-18 67.2 0.5 1.6e-08 34.9 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAO90670.1 - 2.4e-09 36.8 0.1 6.9e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAO90670.1 - 4.9e-07 29.3 0.0 0.00075 18.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Arb2 PF09757.4 GAO90671.1 - 7e-33 113.5 0.0 9.4e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 GAO90672.1 - 5.2e-19 67.3 0.3 6.5e-18 63.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DASH_Spc19 PF08287.6 GAO90673.1 - 1.5e-54 183.7 8.5 2.1e-54 183.2 5.9 1.2 1 0 0 1 1 1 1 Spc19 Occludin_ELL PF07303.8 GAO90673.1 - 0.02 15.5 0.6 1.5 9.5 0.0 2.5 2 1 0 2 2 2 0 Occludin homology domain Mur_ligase_M PF08245.7 GAO90673.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Mur ligase middle domain HALZ PF02183.13 GAO90673.1 - 0.071 12.8 7.3 0.68 9.7 1.0 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 GAO90673.1 - 0.078 12.1 2.5 0.11 11.7 1.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 GAO90673.1 - 0.53 10.2 8.8 3.3 7.6 0.2 3.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 IFP_35_N PF07334.8 GAO90673.1 - 0.83 9.6 6.2 2.1 8.3 1.4 2.7 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4407 PF14362.1 GAO90673.1 - 1.3 7.9 5.7 1.8 7.4 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.1 GAO90673.1 - 5.5 7.0 12.4 7.1 6.6 7.1 2.0 2 1 0 2 2 2 0 Up-regulated During Septation Rogdi_lz PF10259.4 GAO90674.1 - 4.2e-81 272.0 0.0 5.6e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 GAO90674.1 - 1.4e-28 99.7 0.1 2.1e-27 95.8 0.1 2.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF1978 PF09321.5 GAO90674.1 - 0.34 10.3 2.3 0.4 10.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) SUR7 PF06687.7 GAO90675.1 - 4.9e-41 140.6 7.6 5.7e-41 140.4 5.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.6 GAO90675.1 - 0.77 9.3 15.2 0.067 12.8 6.8 1.9 2 1 0 2 2 2 0 Amastin surface glycoprotein Claudin_2 PF13903.1 GAO90675.1 - 1.1 8.9 18.5 0.14 11.8 6.8 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 GAO90675.1 - 4 6.6 9.3 0.8 8.9 3.9 1.7 1 1 1 2 2 2 0 Clc-like HSP70 PF00012.15 GAO90676.1 - 1.3e-83 280.9 0.4 2.1e-83 280.2 0.3 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO90676.1 - 1.5e-08 33.6 0.3 2.6e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FAM176 PF14851.1 GAO90676.1 - 0.12 12.1 1.1 0.22 11.1 0.7 1.4 1 0 0 1 1 1 0 FAM176 family EBV-NA3 PF05009.7 GAO90676.1 - 9.4 5.4 6.2 17 4.5 4.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) EXOSC1 PF10447.4 GAO90677.1 - 0.066 13.1 0.0 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Myb_DNA-bind_6 PF13921.1 GAO90678.1 - 3e-16 59.2 1.5 6.6e-12 45.3 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO90678.1 - 5.6e-11 42.3 1.9 5.7e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAO90678.1 - 7.5e-05 22.7 0.8 0.0015 18.6 0.3 3.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain UDP-g_GGTase PF06427.6 GAO90679.1 - 4.5e-66 222.1 0.0 8.2e-66 221.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 GAO90679.1 - 0.00015 21.1 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 HNH_2 PF13391.1 GAO90680.1 - 7.9e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Spore_II_R PF09551.5 GAO90682.1 - 0.14 12.1 0.5 0.23 11.4 0.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) FemAB PF02388.11 GAO90682.1 - 0.73 8.4 4.1 1.6 7.3 2.8 1.5 1 1 0 1 1 1 0 FemAB family Rpp20 PF12328.3 GAO90683.1 - 1.7e-55 186.6 12.9 4.5e-55 185.2 8.9 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 GAO90683.1 - 3.6e-26 90.5 1.1 3.6e-26 90.5 0.8 1.6 2 0 0 2 2 2 1 Alba BNIP3 PF06553.7 GAO90683.1 - 3.2 7.0 9.2 1.7 7.9 2.7 2.1 1 1 1 2 2 2 0 BNIP3 FYDLN_acid PF09538.5 GAO90683.1 - 5.2 7.6 11.7 5.4 7.6 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) FHA PF00498.21 GAO90684.1 - 6.4e-18 64.6 0.0 1.9e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 GAO90684.1 - 0.0041 16.6 11.4 0.0041 16.6 7.9 3.1 3 0 0 3 3 3 2 Ezrin/radixin/moesin family Gas_vesicle_C PF01304.12 GAO90684.1 - 0.024 14.2 1.9 0.072 12.7 1.3 1.9 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain DUF1664 PF07889.7 GAO90684.1 - 0.72 9.6 7.0 1.3 8.8 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Romo1 PF10247.4 GAO90685.1 - 1e-23 83.2 13.8 4.1e-20 71.7 6.4 2.1 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 NfeD PF01957.13 GAO90685.1 - 0.12 12.5 0.8 0.16 12.1 0.6 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3281 PF11685.3 GAO90686.1 - 0.0038 16.4 1.2 0.0043 16.2 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3281) Atrophin-1 PF03154.10 GAO90686.1 - 1.8 6.5 12.8 1.9 6.5 8.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Herpes_capsid PF06112.6 GAO90686.1 - 4.1 7.4 15.4 5 7.1 10.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BASP1 PF05466.7 GAO90686.1 - 8.9 6.0 10.3 10 5.8 7.2 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) LRR_4 PF12799.2 GAO90687.1 - 1.1e-12 47.2 2.7 3.6e-07 29.6 0.3 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO90687.1 - 5.4e-10 38.8 2.1 5.8e-09 35.5 0.2 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 GAO90687.1 - 3.2e-05 23.3 3.4 0.0097 15.8 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 GAO90687.1 - 0.009 16.0 2.5 0.11 12.8 0.1 3.6 3 0 0 3 3 3 1 Leucine rich repeat AAA_19 PF13245.1 GAO90689.1 - 8.2e-08 31.8 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 GAO90689.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 GAO90689.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF390 PF04094.9 GAO90691.1 - 0.31 9.0 3.1 0.3 9.0 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-RING_2 PF13639.1 GAO90692.1 - 4.8e-14 51.9 5.8 7.6e-14 51.2 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 GAO90692.1 - 1e-12 47.6 0.0 2.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 GAO90692.1 - 1.5e-09 37.7 5.4 2.3e-09 37.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAO90692.1 - 2.8e-09 36.9 1.3 5e-09 36.1 0.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAO90692.1 - 1.6e-08 34.0 3.9 2.6e-08 33.3 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAO90692.1 - 2.7e-08 33.3 3.2 4.1e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAO90692.1 - 1.2e-07 31.3 2.9 1.9e-07 30.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAO90692.1 - 0.00048 19.9 0.5 0.00087 19.0 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAO90692.1 - 0.019 14.6 3.2 0.045 13.4 2.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 GAO90692.1 - 0.05 13.5 2.9 0.13 12.1 2.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 GAO90692.1 - 0.067 13.0 3.6 0.2 11.5 2.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 GAO90692.1 - 0.073 13.1 4.4 0.14 12.2 3.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 GAO90692.1 - 0.46 10.0 3.1 0.79 9.3 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 GAO90692.1 - 1.3 8.8 3.0 2.2 8.0 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 GAO90692.1 - 1.9 8.5 3.9 3.6 7.6 2.7 1.5 1 0 0 1 1 1 0 RING-like domain adh_short PF00106.20 GAO90693.1 - 2.3e-10 40.6 0.6 5.2e-10 39.4 0.4 1.6 1 0 0 1 1 1 1 short chain dehydrogenase EI24 PF07264.6 GAO90693.1 - 4e-07 29.6 3.8 7.3e-07 28.8 2.7 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) NmrA PF05368.8 GAO90693.1 - 1.2e-06 27.9 1.1 2.2e-06 27.1 0.8 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90693.1 - 2.9e-06 27.4 0.6 6.5e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAO90693.1 - 2.5e-05 23.9 0.3 2.5e-05 23.9 0.2 1.9 3 0 0 3 3 3 1 KR domain Epimerase PF01370.16 GAO90693.1 - 0.0012 18.3 0.2 0.002 17.6 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO90693.1 - 0.0075 16.0 0.3 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DapB_N PF01113.15 GAO90693.1 - 0.011 15.6 0.5 0.023 14.5 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GST_N_2 PF13409.1 GAO90694.1 - 2.5e-09 37.0 0.1 6.8e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAO90694.1 - 3.4e-09 36.8 0.0 9e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAO90694.1 - 1.1e-08 34.8 1.2 2.2e-08 33.8 0.6 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAO90694.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAO90694.1 - 0.07 13.6 0.1 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 GAO90694.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2263 PF10021.4 GAO90695.1 - 4e-25 88.5 0.0 6.6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 GAO90695.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Macro domain Raptor_N PF14538.1 GAO90696.1 - 1.4e-64 216.6 0.0 2.4e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 GAO90696.1 - 4e-07 29.6 5.4 0.21 11.5 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Peptidase_C14 PF00656.17 GAO90696.1 - 0.00053 19.7 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain BBS2_Mid PF14783.1 GAO90696.1 - 0.0025 17.5 2.0 0.79 9.5 0.1 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF1546 PF07571.8 GAO90696.1 - 0.038 14.1 0.0 0.72 10.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) Atx10homo_assoc PF09759.4 GAO90696.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 GAO90696.1 - 0.11 12.6 0.2 24 5.3 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Kelch_3 PF13415.1 GAO90697.1 - 2.5e-34 116.6 11.8 1.2e-07 31.6 0.1 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAO90697.1 - 3.4e-33 113.1 8.7 4.8e-08 32.6 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAO90697.1 - 1.8e-30 104.3 3.1 2.4e-06 27.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAO90697.1 - 8.6e-30 102.0 0.1 5.5e-10 38.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAO90697.1 - 1.3e-26 91.5 8.0 4.1e-10 39.3 0.2 6.4 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAO90697.1 - 2.7e-20 71.2 2.3 6.8e-07 28.8 0.1 6.4 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 GAO90697.1 - 0.041 12.5 0.1 1 7.9 0.0 3.1 3 1 1 4 4 4 0 Recombination activating protein 2 Pkinase PF00069.20 GAO90698.1 - 7.6e-38 130.1 0.0 1.2e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90698.1 - 3.1e-13 49.3 0.0 4.6e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase bZIP_1 PF00170.16 GAO90698.1 - 4.8e-06 26.4 7.9 4.8e-06 26.4 5.5 2.4 2 0 0 2 2 2 1 bZIP transcription factor APH PF01636.18 GAO90698.1 - 6.3e-05 22.8 0.0 0.0031 17.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF972 PF06156.8 GAO90698.1 - 0.014 15.6 0.1 0.041 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 GAO90698.1 - 0.035 13.8 1.8 0.075 12.7 1.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 GAO90698.1 - 0.036 14.3 1.9 0.092 13.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 GAO90698.1 - 0.047 13.1 0.4 0.13 11.7 0.3 1.8 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.1 GAO90698.1 - 0.073 12.2 2.7 0.14 11.2 1.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.13 GAO90698.1 - 0.11 12.5 2.1 7.5 6.5 1.2 3.1 2 1 0 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 GAO90698.1 - 0.31 8.8 0.3 0.41 8.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 GAO90698.1 - 1.8 8.4 11.7 0.72 9.7 4.4 2.8 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 GAO90698.1 - 4.5 7.1 12.6 0.044 13.6 3.2 1.7 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Phosducin PF02114.11 GAO90699.1 - 1.7e-13 49.9 0.1 2.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin EF-1_beta_acid PF10587.4 GAO90699.1 - 0.066 13.3 2.7 0.066 13.3 1.9 2.4 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Adaptin_N PF01602.15 GAO90700.1 - 6.7e-112 374.4 0.1 9.6e-112 373.9 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 GAO90700.1 - 4.7e-61 205.0 3.5 9.8e-61 203.9 2.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 GAO90700.1 - 2.2e-15 56.6 1.8 1.5e-05 25.2 0.0 6.5 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 GAO90700.1 - 0.00098 19.0 9.8 0.14 12.3 0.2 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.11 GAO90700.1 - 0.0053 17.1 2.0 12 6.6 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.11 GAO90700.1 - 0.021 14.7 0.2 0.085 12.8 0.0 2.2 3 0 0 3 3 3 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 GAO90700.1 - 0.033 14.6 3.0 0.11 13.0 0.4 3.2 3 0 0 3 3 3 0 HEAT-like repeat F-box-like PF12937.2 GAO90701.1 - 7.2e-09 35.2 0.3 1.5e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 GAO90701.1 - 0.00088 18.9 4.3 0.34 10.6 0.1 3.7 1 1 2 3 3 3 3 Leucine rich repeat F-box PF00646.28 GAO90701.1 - 0.0063 16.1 0.0 0.033 13.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 GAO90701.1 - 0.014 15.0 6.0 0.061 12.9 0.0 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 GAO90701.1 - 9.7 6.9 9.5 1.7e+02 3.1 0.1 5.7 7 0 0 7 7 7 0 Leucine rich repeat Hydrolase_6 PF13344.1 GAO90702.1 - 2.5e-24 85.1 0.0 4.2e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAO90702.1 - 6.5e-18 64.2 0.0 1.5e-16 59.8 0.0 3.0 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAO90702.1 - 6.8e-06 26.4 0.0 0.015 15.5 0.0 3.5 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAO90702.1 - 0.0014 19.0 0.0 0.41 11.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 GAO90703.1 - 1.3e-72 244.4 0.1 1.7e-72 244.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAO90703.1 - 4.7e-07 29.5 0.1 8.2e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peripla_BP_3 PF13377.1 GAO90703.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF1570 PF07607.6 GAO90703.1 - 0.095 12.7 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) Neisseria_TspB PF05616.8 GAO90703.1 - 0.37 9.1 4.2 0.6 8.4 2.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SIP1 PF04938.7 GAO90704.1 - 1.3e-06 27.9 0.1 0.0028 17.0 0.0 2.5 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PX PF00787.19 GAO90705.1 - 6.7e-16 58.0 0.0 3.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 GAO90705.1 - 3.9e-06 26.4 5.1 3.9e-06 26.4 3.5 2.1 2 0 0 2 2 2 1 SNARE domain DGF-1_C PF11040.3 GAO90705.1 - 0.074 12.9 0.4 0.4 10.5 0.0 2.5 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ku PF02735.11 GAO90706.1 - 2.8e-26 92.1 0.0 4.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAO90706.1 - 3.6e-21 75.6 0.0 1.2e-20 73.9 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 GAO90706.1 - 1e-18 67.3 0.2 2.6e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Dak1 PF02733.12 GAO90706.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain DUF4149 PF13664.1 GAO90707.1 - 2e-25 88.7 1.7 2e-25 88.7 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2545 PF10810.3 GAO90707.1 - 0.0053 17.1 0.1 1.7 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2545) BBP1_C PF15272.1 GAO90708.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Topoisom_bac PF01131.15 GAO90709.1 - 1.8e-92 310.2 0.0 2.1e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 GAO90709.1 - 2e-20 72.5 0.0 8.2e-20 70.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF1295 PF06966.7 GAO90710.1 - 8.1e-40 136.5 7.0 1.1e-39 136.1 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 GAO90710.1 - 1 9.6 4.6 6.7 6.9 0.0 3.3 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_M41 PF01434.13 GAO90711.1 - 2.2e-73 246.2 1.5 9.5e-73 244.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 GAO90711.1 - 3.1e-43 147.1 0.0 7.4e-43 145.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 GAO90711.1 - 1.1e-09 38.4 0.1 9.1e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 GAO90711.1 - 8.1e-05 22.3 0.0 0.00043 20.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAO90711.1 - 0.00079 19.5 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAO90711.1 - 0.0048 17.7 0.0 0.014 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAO90711.1 - 0.0074 15.0 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 GAO90711.1 - 0.012 14.6 0.0 0.036 13.0 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAO90711.1 - 0.019 14.7 0.5 0.019 14.7 0.4 2.4 3 0 0 3 3 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAO90711.1 - 0.026 13.9 0.1 0.074 12.4 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 GAO90711.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Serinc PF03348.10 GAO90711.1 - 0.05 12.3 0.9 0.075 11.7 0.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_25 PF13481.1 GAO90711.1 - 0.052 12.9 1.6 0.14 11.5 0.2 2.3 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 GAO90711.1 - 0.065 13.2 3.1 0.15 12.0 0.1 2.8 2 1 0 3 3 3 0 AAA ATPase domain AAA_2 PF07724.9 GAO90711.1 - 0.07 13.0 1.9 0.17 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 GAO90711.1 - 0.11 12.7 2.0 0.64 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 GAO90711.1 - 0.13 12.1 0.7 0.42 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 GAO90711.1 - 0.52 9.8 4.9 13 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4175 PF13779.1 GAO90711.1 - 7.9 4.0 24.5 12 3.4 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Fungal_trans PF04082.13 GAO90712.1 - 1.4e-31 109.3 0.1 5.9e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90712.1 - 1.1e-09 37.9 13.9 1.9e-09 37.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 GAO90713.1 - 9.6e-08 31.6 0.1 1.3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 GAO90713.1 - 1.4e-07 31.3 0.0 1.7e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 GAO90714.1 - 4.1e-27 93.8 2.7 9.6e-27 92.6 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-C2H2_4 PF13894.1 GAO90716.1 - 0.025 14.9 1.8 0.074 13.4 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAO90716.1 - 0.28 11.6 3.0 0.72 10.3 2.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_18 PF12847.2 GAO90717.1 - 2.4e-17 63.5 0.0 6.9e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90717.1 - 1e-13 51.1 0.0 1.8e-09 37.3 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90717.1 - 1.5e-05 24.8 0.0 5.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90717.1 - 0.00011 22.6 0.3 0.0036 17.7 0.0 2.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90717.1 - 0.00019 21.4 0.0 0.00082 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90717.1 - 0.00023 21.5 0.0 0.0023 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90717.1 - 0.0014 18.9 0.0 0.0037 17.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAO90717.1 - 0.0038 16.6 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 GAO90717.1 - 0.0092 15.3 0.0 0.04 13.2 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PrmA PF06325.8 GAO90717.1 - 0.04 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAO90717.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CENP-B_dimeris PF09026.5 GAO90717.1 - 8.3 6.7 12.5 3 8.1 2.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DSPc PF00782.15 GAO90718.1 - 1.7e-22 79.4 0.0 7.4e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAO90718.1 - 0.22 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KH_1 PF00013.24 GAO90720.1 - 1.6e-40 136.5 7.7 5.8e-16 57.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAO90720.1 - 4.1e-30 102.8 11.4 1.5e-11 43.6 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAO90720.1 - 2.3e-10 39.9 8.0 0.002 17.6 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAO90720.1 - 6.3e-08 32.1 6.5 0.032 13.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAO90720.1 - 0.00026 20.7 3.9 0.44 10.3 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 GAO90720.1 - 0.0062 15.9 0.1 0.92 8.9 0.0 3.1 3 0 0 3 3 3 1 dUTPase ADH_N PF08240.7 GAO90721.1 - 4.2e-30 103.7 1.3 7.3e-30 102.9 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAO90721.1 - 2.4e-17 62.7 0.0 4.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAO90721.1 - 0.00074 19.1 0.1 0.0021 17.6 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RabGAP-TBC PF00566.13 GAO90723.1 - 3.5e-36 124.6 0.9 3.5e-36 124.6 0.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4515 PF14988.1 GAO90723.1 - 0.082 12.5 5.4 0.087 12.4 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Pkinase PF00069.20 GAO90724.1 - 8.5e-60 202.0 0.0 1.3e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90724.1 - 1.9e-21 76.2 0.0 3.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAO90724.1 - 5.2e-06 25.6 0.0 8.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAO90724.1 - 3.5e-05 23.6 1.1 0.00084 19.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAO90724.1 - 0.0013 18.1 0.4 0.0033 16.8 0.3 1.6 1 1 0 1 1 1 1 RIO1 family F-box-like PF12937.2 GAO90725.1 - 3.3e-13 49.1 0.0 8.2e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 GAO90725.1 - 1.6e-11 42.9 8.8 0.93 9.7 0.0 8.6 11 0 0 11 11 11 4 Leucine Rich repeat F-box PF00646.28 GAO90725.1 - 4.9e-10 38.7 0.0 2e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 GAO90725.1 - 2.6e-06 26.8 4.3 0.011 15.3 0.0 5.5 3 1 4 7 7 7 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAO90725.1 - 3.2e-06 26.7 6.4 0.042 13.6 0.0 4.3 4 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 GAO90725.1 - 0.00071 19.2 11.1 8.9 6.7 0.1 7.6 7 3 0 7 7 7 1 Leucine Rich Repeat PRANC PF09372.5 GAO90725.1 - 0.0057 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 PRANC domain LRR_7 PF13504.1 GAO90725.1 - 0.96 9.9 12.3 14 6.4 0.0 6.7 8 0 0 8 8 8 0 Leucine rich repeat DUF2361 PF10153.4 GAO90726.1 - 1.6e-35 121.7 6.2 1.6e-35 121.7 4.3 2.4 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 GAO90727.1 - 0.00081 19.1 0.2 7 6.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat FUSC PF04632.7 GAO90727.1 - 0.75 8.1 4.4 1.1 7.6 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PTS_2-RNA PF01885.11 GAO90728.1 - 1.7e-74 249.1 0.0 3.1e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Dioxygenase_C PF00775.16 GAO90728.1 - 2.9e-51 173.3 0.0 5.6e-51 172.3 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAO90728.1 - 1.9e-12 46.9 0.1 4.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAO90728.1 - 2.7e-05 24.1 0.0 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 GAO90728.1 - 0.094 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Abhydrolase_6 PF12697.2 GAO90729.1 - 4.3e-33 115.1 0.0 7.1e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAO90729.1 - 3.4e-19 69.0 0.0 6.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO90729.1 - 7.5e-19 68.2 0.0 9.4e-17 61.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 GAO90729.1 - 8.3e-06 25.6 1.7 1.1e-05 25.2 0.0 2.0 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 GAO90729.1 - 0.00023 20.6 0.1 0.096 12.1 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ndr PF03096.9 GAO90729.1 - 0.00091 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 GAO90729.1 - 0.005 16.0 0.0 0.21 10.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF915 PF06028.6 GAO90729.1 - 0.0078 15.3 0.0 0.091 11.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 GAO90729.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 GAO90729.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 GAO90729.1 - 0.03 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAO90729.1 - 0.031 13.8 0.5 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.7 GAO90729.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.2 GAO90729.1 - 0.48 9.2 1.4 1.7 7.4 1.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme YqfQ PF14181.1 GAO90729.1 - 7.2 6.6 8.2 31 4.5 5.5 2.0 2 0 0 2 2 2 0 YqfQ-like protein Aldo_ket_red PF00248.16 GAO90730.1 - 6.2e-43 146.6 0.0 8.4e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF718 PF05336.8 GAO90730.1 - 0.11 12.3 0.1 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF718) eRF1_1 PF03463.10 GAO90731.1 - 2.1e-44 150.3 0.0 3.2e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 GAO90731.1 - 2.9e-17 63.2 0.0 5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAO90731.1 - 5e-17 62.1 0.0 9.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Myb_DNA-bind_3 PF12776.2 GAO90732.1 - 0.16 12.6 8.7 0.83 10.3 1.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ER_lumen_recept PF00810.13 GAO90733.1 - 2.7e-41 141.5 9.1 4e-41 140.9 6.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAO90733.1 - 0.029 13.8 0.0 0.029 13.8 0.0 3.6 3 1 0 3 3 3 0 PQ loop repeat WBP-1 PF11669.3 GAO90733.1 - 1.4 9.0 4.2 4.1 7.5 0.2 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Cation_ATPase_C PF00689.16 GAO90733.1 - 3.1 7.2 10.4 0.24 10.9 3.8 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Transp_cyt_pur PF02133.10 GAO90734.1 - 9.1e-18 64.0 39.8 1.7e-17 63.1 27.6 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Myb_DNA-bind_6 PF13921.1 GAO90734.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain COX5B PF01215.14 GAO90735.1 - 3e-37 127.3 0.0 5.6e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-bind_6 PF13921.1 GAO90735.1 - 4.3e-09 36.3 0.1 8.4e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAO90735.1 - 3e-05 23.9 0.0 7.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PROCN PF08083.6 GAO90736.1 - 7.3e-224 742.7 8.8 1.1e-223 742.0 6.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 GAO90736.1 - 1.3e-125 417.2 1.7 2.3e-125 416.5 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 GAO90736.1 - 1.2e-94 313.9 1.2 2.8e-94 312.8 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 GAO90736.1 - 8.1e-78 259.3 2.8 1.4e-77 258.5 1.2 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 GAO90736.1 - 2.5e-67 224.6 0.1 5.6e-67 223.5 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 GAO90736.1 - 1e-45 154.4 0.0 2.7e-45 153.0 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 GAO90736.1 - 9.3e-45 150.4 0.2 2.9e-44 148.8 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 GAO90736.1 - 0.083 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 GAO90737.1 - 5.3e-38 129.1 3.2 6.9e-38 128.7 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cactin_mid PF10312.4 GAO90738.1 - 2e-64 216.3 5.7 3.3e-64 215.6 4.0 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 GAO90738.1 - 3.9e-50 168.6 2.2 7.7e-50 167.6 1.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 GAO90738.1 - 2.6e-16 59.4 0.3 1.3e-15 57.2 0.2 2.1 2 0 0 2 2 2 1 Fork head domain XLF PF09302.6 GAO90739.1 - 3.6e-35 121.2 0.7 4.6e-35 120.9 0.0 1.5 2 0 0 2 2 2 1 XLF (XRCC4-like factor) BNIP2 PF12496.3 GAO90739.1 - 1.1 9.3 8.2 0.68 10.1 3.8 2.2 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 WD40 PF00400.27 GAO90740.1 - 1.5e-27 94.4 14.8 6.4e-10 38.5 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAO90740.1 - 1.8e-05 24.5 0.0 0.004 16.8 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 GAO90740.1 - 1.3 9.2 6.6 0.78 9.8 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger ABC_tran PF00005.22 GAO90741.1 - 5.7e-33 114.1 0.0 1.4e-32 112.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAO90741.1 - 1e-31 110.3 8.6 1e-31 110.3 6.0 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 GAO90741.1 - 1.2e-08 34.4 1.0 1.1e-05 24.7 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAO90741.1 - 7.3e-05 22.8 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 GAO90741.1 - 0.0024 17.8 0.2 0.0089 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAO90741.1 - 0.0037 17.4 0.1 0.027 14.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAO90741.1 - 0.0043 16.9 0.2 0.056 13.3 0.1 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAO90741.1 - 0.0074 15.7 0.2 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAO90741.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAO90741.1 - 0.05 13.0 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Alk_phosphatase PF00245.15 GAO90742.1 - 5.3e-114 381.1 0.0 6.5e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF498 PF04430.9 GAO90742.1 - 2.2e-27 94.7 0.0 5e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Metalloenzyme PF01676.13 GAO90742.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Ribosomal_S2 PF00318.15 GAO90742.1 - 0.056 12.6 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 Glyco_hydro_16 PF00722.16 GAO90743.1 - 1.1e-42 145.4 3.6 1.8e-42 144.7 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WAP PF00095.16 GAO90743.1 - 0.0048 16.8 4.2 0.0098 15.8 2.9 1.5 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chitin_bind_1 PF00187.14 GAO90743.1 - 0.1 12.5 14.0 0.27 11.2 9.7 1.7 1 0 0 1 1 1 0 Chitin recognition protein PMSR PF01625.16 GAO90744.1 - 2.4e-60 202.9 1.0 3.2e-60 202.5 0.1 1.7 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 GAO90744.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiA domain Kinesin PF00225.18 GAO90745.1 - 4.4e-115 383.9 0.0 7.2e-115 383.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 GAO90745.1 - 0.0095 15.8 0.2 0.082 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sox_N PF12444.3 GAO90745.1 - 0.17 13.0 0.0 0.17 13.0 0.0 3.2 3 1 0 3 3 3 0 Sox developmental protein N terminal UCR_Fe-S_N PF10399.4 GAO90747.1 - 0.15 11.2 0.1 0.32 10.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal cNMP_binding PF00027.24 GAO90748.1 - 2.7e-36 123.2 0.0 3e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 GAO90748.1 - 2e-14 51.9 6.5 0.45 10.7 0.1 9.2 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.2 GAO90748.1 - 1.3e-06 27.9 2.8 1.9e-06 27.5 0.4 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 GAO90748.1 - 1.9e-06 27.5 0.4 0.02 14.6 0.2 4.5 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 GAO90748.1 - 7.3e-05 22.2 12.1 13 6.3 0.1 8.8 7 3 2 9 9 9 1 Leucine Rich Repeat F-box PF00646.28 GAO90748.1 - 8.1e-05 22.1 0.2 8.1e-05 22.1 0.1 3.1 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 GAO90748.1 - 0.015 15.3 13.5 51 4.7 0.0 7.3 8 0 0 8 8 8 0 Leucine rich repeat Ste50p-SAM PF09235.5 GAO90748.1 - 0.065 13.2 0.8 6 6.9 0.0 3.3 3 1 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.13 GAO90749.1 - 0.00081 19.2 7.6 0.0021 17.9 5.3 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 GAO90749.1 - 0.82 7.8 8.1 1.4 7.1 5.6 1.3 1 0 0 1 1 1 0 Transmembrane protein bZIP_2 PF07716.10 GAO90749.1 - 7.9 6.3 10.0 3.8 7.4 1.3 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Slx4 PF09494.5 GAO90750.1 - 3.3e-28 97.2 0.0 6.1e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 GAO90751.1 - 2.3e-57 193.1 0.0 2.6e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 GAO90752.1 - 5.7e-28 97.9 12.0 9.1e-28 97.2 8.3 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.19 GAO90753.1 - 8.6e-60 202.7 0.3 1.1e-59 202.3 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAO90753.1 - 3.4e-29 100.7 0.2 8.7e-29 99.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) RRM_1 PF00076.17 GAO90755.1 - 1.2e-14 53.7 0.0 1.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90755.1 - 3.7e-12 46.0 0.0 5.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO90755.1 - 4.3e-11 42.5 0.0 5.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 GAO90756.1 - 3.7e-20 72.6 0.0 5.3e-14 52.3 0.0 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Mur_ligase_C PF02875.16 GAO90756.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF2205 PF10224.4 GAO90757.1 - 2.1e-31 107.3 3.1 2.1e-31 107.3 2.2 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Spectrin PF00435.16 GAO90757.1 - 0.0051 17.0 1.1 0.0077 16.5 0.7 1.3 1 0 0 1 1 1 1 Spectrin repeat LCD1 PF09798.4 GAO90757.1 - 0.0082 14.1 3.7 0.009 14.0 2.6 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein IncA PF04156.9 GAO90757.1 - 0.015 14.8 2.0 0.014 14.9 1.4 1.2 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 GAO90757.1 - 0.016 13.5 5.5 0.017 13.4 3.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 GAO90757.1 - 0.018 15.3 3.2 0.028 14.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 GAO90757.1 - 0.019 15.3 1.2 0.034 14.5 0.9 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 GAO90757.1 - 0.026 14.4 2.7 0.036 13.9 1.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.4 GAO90757.1 - 0.028 14.2 3.3 0.055 13.3 2.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 GAO90757.1 - 0.038 13.4 1.7 0.062 12.7 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.5 GAO90757.1 - 0.044 13.5 0.1 0.081 12.7 0.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Dam1 HALZ PF02183.13 GAO90757.1 - 0.064 12.9 4.1 0.55 9.9 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 GAO90757.1 - 0.086 12.6 0.4 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 GAO90757.1 - 0.088 11.4 3.4 0.1 11.2 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 GAO90757.1 - 0.09 12.6 5.1 0.12 12.2 3.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ApoO PF09769.4 GAO90757.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3782 PF12644.2 GAO90757.1 - 0.18 11.6 0.9 0.33 10.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Sas10_Utp3 PF04000.10 GAO90757.1 - 0.27 11.4 1.8 0.52 10.5 1.2 1.6 1 1 0 1 1 1 0 Sas10/Utp3/C1D family DUF904 PF06005.7 GAO90757.1 - 0.35 11.1 3.8 1.2 9.4 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) YtxH PF12732.2 GAO90757.1 - 0.82 10.0 3.2 1.3 9.4 2.2 1.4 1 1 0 1 1 1 0 YtxH-like protein 14-3-3 PF00244.15 GAO90758.1 - 1.1e-115 384.7 4.9 1.2e-115 384.5 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.7 GAO90759.1 - 8.9e-25 86.6 0.3 1e-24 86.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 GAO90759.1 - 0.0041 16.1 0.2 0.0045 15.9 0.2 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 GAO90759.1 - 0.036 13.6 0.2 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 GAO90759.1 - 0.066 12.5 1.0 0.074 12.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FtsQ PF03799.10 GAO90759.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Cell division protein FtsQ Nsp1_C PF05064.8 GAO90760.1 - 1.5e-41 140.7 1.3 3.8e-41 139.4 0.9 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 GAO90760.1 - 8.9e-09 35.5 207.6 8.2e-07 29.2 26.8 6.6 1 1 4 5 5 2 2 Nucleoporin FG repeat region APG17 PF04108.7 GAO90760.1 - 0.18 10.5 4.4 0.25 10.1 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 WXG100 PF06013.7 GAO90760.1 - 0.19 11.7 4.4 0.084 12.8 0.3 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Myosin_tail_1 PF01576.14 GAO90760.1 - 0.2 9.3 10.2 0.3 8.7 7.1 1.2 1 0 0 1 1 1 0 Myosin tail ParB PF08775.5 GAO90760.1 - 0.46 10.8 4.1 0.17 12.2 0.3 1.9 2 0 0 2 2 2 0 ParB family APG6 PF04111.7 GAO90760.1 - 0.58 9.1 8.4 0.91 8.5 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 GAO90760.1 - 0.79 8.1 8.2 0.39 9.1 1.8 1.9 1 1 1 2 2 2 0 AAA domain DUF4200 PF13863.1 GAO90760.1 - 0.94 9.4 12.6 0.14 12.1 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 GAO90760.1 - 1.5 8.6 4.8 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 GAO90760.1 - 2.2 8.0 8.9 5.7 6.6 0.6 2.3 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 GAO90760.1 - 2.5 6.7 11.9 2 7.0 0.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin PF00804.20 GAO90760.1 - 3.4 7.8 5.8 29 4.8 3.5 2.3 1 1 0 1 1 1 0 Syntaxin ERM PF00769.14 GAO90760.1 - 6.8 6.1 11.7 21 4.5 8.1 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fcf1 PF04900.7 GAO90761.1 - 1.7e-35 121.1 0.0 3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Fcf1 PhyH PF05721.8 GAO90761.1 - 1.8e-07 31.4 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-MIZ PF02891.15 GAO90762.1 - 3.5e-11 42.4 0.0 6.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rubredoxin PF00301.15 GAO90762.1 - 0.065 13.1 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Rubredoxin SH3_9 PF14604.1 GAO90763.1 - 1.1e-11 44.0 0.1 2.4e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 GAO90763.1 - 1.2e-10 41.4 0.0 4.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 GAO90763.1 - 1.8e-10 40.0 0.1 3.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 GAO90763.1 - 4.3e-10 39.3 0.0 7.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 GAO90763.1 - 1.4e-06 28.4 0.0 4.1e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 GAO90763.1 - 1.5e-05 24.4 0.1 3.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 GAO90763.1 - 0.022 14.8 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.25 GAO90763.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Metallophos PF00149.23 GAO90764.1 - 1.3e-08 34.5 2.1 2.9e-08 33.3 1.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hist_deacetyl PF00850.14 GAO90765.1 - 3.7e-78 262.9 0.0 5.9e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L14 PF00238.14 GAO90765.1 - 8.7e-32 109.4 0.0 1.4e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e JAB PF01398.16 GAO90766.1 - 7e-36 122.4 0.1 1.4e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAO90766.1 - 1.2e-28 99.4 2.8 2.2e-28 98.6 1.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 GAO90766.1 - 6e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 GAO90766.1 - 0.041 13.6 0.2 0.081 12.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit NIF PF03031.13 GAO90768.1 - 1.3e-39 135.4 0.1 1.9e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 GAO90768.1 - 0.077 13.2 0.8 0.2 11.8 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 GAO90769.1 - 8.1e-19 67.5 0.0 3e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90769.1 - 5.1e-07 29.4 5.7 1.2e-06 28.3 4.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAO90769.1 - 4.3 7.5 10.0 23 5.2 3.3 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region F-box-like PF12937.2 GAO90770.1 - 0.0013 18.4 0.2 0.0033 17.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO90770.1 - 0.0093 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 GAO90770.1 - 2.3 8.2 10.5 21 5.1 0.1 4.9 4 1 0 4 4 4 0 WD domain, G-beta repeat DUF1399 PF07173.7 GAO90771.1 - 3.1e-19 69.6 2.5 1.1e-16 61.3 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 GAO90772.1 - 8.7e-13 47.7 1.4 1.4e-12 47.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90772.1 - 3.3e-06 26.9 10.9 7.3e-06 25.7 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_G PF02306.10 GAO90773.1 - 0.029 13.9 2.1 0.048 13.2 1.5 1.3 1 0 0 1 1 1 0 Major spike protein (G protein) PhnG PF06754.7 GAO90773.1 - 0.94 9.0 5.7 0.13 11.8 1.3 1.6 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Pkinase PF00069.20 GAO90775.1 - 1.6e-67 227.3 0.0 4.4e-61 206.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90775.1 - 3.6e-33 114.7 0.0 3.1e-28 98.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAO90775.1 - 0.0017 17.3 0.2 0.78 8.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like MFS_1 PF07690.11 GAO90776.1 - 3.2e-29 101.7 33.9 4.3e-19 68.4 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90776.1 - 2.8e-22 78.9 18.0 5.7e-22 77.9 12.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_S10 PF00450.17 GAO90777.1 - 2.1e-95 320.3 0.2 2.8e-95 319.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 GAO90778.1 - 2.9e-31 108.4 39.2 2.9e-31 108.4 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90778.1 - 3.3e-10 39.1 40.5 1.9e-09 36.6 11.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAO90778.1 - 2.8e-06 25.9 27.5 3.4e-06 25.7 17.9 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein DUF969 PF06149.7 GAO90778.1 - 0.93 8.7 7.5 0.16 11.1 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF969) HAMP PF00672.20 GAO90780.1 - 1.2e-49 166.3 16.6 8e-10 38.7 0.4 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 GAO90780.1 - 1.8e-31 108.1 0.1 6.7e-31 106.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAO90780.1 - 6.1e-29 100.2 2.0 3.8e-26 91.2 0.2 3.8 2 1 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 GAO90780.1 - 1e-16 60.6 4.5 4.5e-16 58.6 0.1 4.3 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 GAO90780.1 - 0.0007 19.4 15.8 1.6 8.6 0.1 7.0 6 1 0 7 7 7 2 Uncharacterized conserved protein (DUF2365) NOD PF06816.8 GAO90780.1 - 0.04 13.0 0.1 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein PilJ PF13675.1 GAO90780.1 - 0.067 13.5 8.3 10 6.4 0.1 6.0 4 2 3 7 7 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_13 PF13166.1 GAO90780.1 - 0.07 11.5 29.5 0.053 11.9 1.8 4.1 1 1 2 4 4 4 0 AAA domain Scaffolding_pro PF11418.3 GAO90780.1 - 0.12 12.6 9.0 39 4.6 0.0 5.7 5 0 0 5 5 5 0 Phi29 scaffolding protein DUF948 PF06103.6 GAO90780.1 - 0.39 10.5 37.5 2.6 7.9 0.5 8.3 3 1 4 8 8 7 0 Bacterial protein of unknown function (DUF948) NAAA-beta PF15508.1 GAO90780.1 - 1.9 8.8 6.6 18 5.7 0.1 5.1 6 2 0 6 6 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IncA PF04156.9 GAO90780.1 - 6.1 6.3 16.1 11 5.5 5.0 4.2 4 0 0 4 4 4 0 IncA protein tRNA-synt_2d PF01409.15 GAO90781.1 - 1.5e-88 296.1 0.0 2.2e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 GAO90781.1 - 5.3e-06 25.4 0.9 0.00025 19.9 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 GAO90781.1 - 0.00096 18.7 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 GAO90781.1 - 0.028 13.5 0.5 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.13 GAO90782.1 - 2.5e-41 139.5 0.1 2.7e-41 139.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 GAO90783.1 - 4.5e-13 49.0 0.1 4.7e-11 42.4 0.0 2.8 1 1 0 1 1 1 1 NUDIX domain Ins145_P3_rec PF08709.6 GAO90783.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor 2OG-FeII_Oxy_5 PF13759.1 GAO90783.1 - 0.15 12.3 0.0 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase IMPDH PF00478.20 GAO90784.1 - 9.7e-133 442.3 2.6 1.2e-132 442.1 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 GAO90784.1 - 8.5e-19 67.0 0.0 6.3e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 GAO90784.1 - 8.2e-07 28.1 0.7 2.1e-06 26.8 0.5 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 GAO90784.1 - 3.6e-06 26.3 9.8 0.045 12.9 6.0 2.9 2 1 1 3 3 3 3 Nitronate monooxygenase His_biosynth PF00977.16 GAO90784.1 - 0.00068 18.9 2.2 0.0025 17.0 1.5 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 GAO90784.1 - 0.0067 15.6 1.0 0.045 12.9 0.1 2.3 2 0 0 2 2 2 1 KDPG and KHG aldolase DUF1273 PF06908.6 GAO90784.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) adh_short PF00106.20 GAO90785.1 - 3.8e-25 88.7 0.4 3.4e-24 85.6 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAO90785.1 - 8.3e-22 78.1 0.1 9e-20 71.4 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAO90785.1 - 2.7e-09 36.9 0.5 6.7e-08 32.4 0.4 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAO90785.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAO90785.1 - 0.00024 20.8 0.1 0.0012 18.6 0.0 2.1 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAO90785.1 - 0.0059 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 GAO90785.1 - 0.013 15.7 0.0 0.094 12.9 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF952 PF06108.7 GAO90786.1 - 2.7e-26 91.2 0.0 3.2e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.10 GAO90787.1 - 9.3e-48 161.5 3.9 9.3e-48 161.5 2.7 2.2 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 GAO90787.1 - 7.3e-44 149.7 0.0 2e-43 148.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 GAO90787.1 - 4.7e-11 42.6 0.0 1.6e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 GAO90787.1 - 2.3e-10 39.1 49.5 0.085 12.5 0.4 14.5 15 0 0 15 15 15 7 IQ calmodulin-binding motif ENTH PF01417.15 GAO90788.1 - 7.2e-44 148.6 0.1 1.3e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAO90788.1 - 0.00099 17.8 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Podoplanin PF05808.6 GAO90789.1 - 0.00013 21.5 0.9 0.00027 20.5 0.6 1.5 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.13 GAO90789.1 - 0.00078 19.2 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Glycophorin A Herpes_gE PF02480.11 GAO90789.1 - 0.0066 14.7 0.0 0.0083 14.4 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 GAO90789.1 - 0.0067 16.1 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 TMEM154 protein family DUF4328 PF14219.1 GAO90789.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) VSP PF03302.8 GAO90789.1 - 0.022 13.4 0.1 0.037 12.6 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1517 PF07466.6 GAO90789.1 - 0.024 13.6 1.1 0.035 13.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) CcmD PF04995.9 GAO90789.1 - 0.029 14.1 2.3 0.043 13.5 1.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MGC-24 PF05283.6 GAO90789.1 - 0.093 12.5 9.7 0.15 11.8 6.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1049 PF06305.6 GAO90789.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CD99L2 PF12301.3 GAO90789.1 - 0.19 11.4 6.3 0.28 10.8 0.2 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 Alpha_GJ PF03229.8 GAO90789.1 - 0.91 9.8 8.2 0.91 9.8 3.8 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J SH3_1 PF00018.23 GAO90790.1 - 7.2e-11 41.2 0.0 1.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAO90790.1 - 5.4e-10 38.6 0.0 1.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO90790.1 - 2e-06 27.1 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Blt1 PF12754.2 GAO90791.1 - 0.0063 16.1 0.6 0.01 15.4 0.4 1.2 1 0 0 1 1 1 1 Cell-cycle control medial ring component HMG-CoA_red PF00368.13 GAO90792.1 - 8.7e-156 518.2 5.6 1.1e-155 517.8 3.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 GAO90792.1 - 1.5e-53 180.6 0.2 3.1e-53 179.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 GAO90792.1 - 3.1e-11 42.9 7.0 2.9e-10 39.7 4.8 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAO90792.1 - 4e-06 25.0 4.7 4e-06 25.0 3.3 1.5 2 0 0 2 2 2 1 Patched family GIT_SHD PF08518.6 GAO90793.1 - 1.2e-24 85.2 10.5 3e-15 55.2 1.8 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 GAO90793.1 - 0.0025 16.9 19.0 0.0025 16.9 13.2 2.8 2 1 1 3 3 3 1 Autophagy protein Apg6 Fumble PF03630.9 GAO90793.1 - 0.083 11.7 4.4 0.19 10.5 3.1 1.5 1 0 0 1 1 1 0 Fumble PspB PF06667.7 GAO90793.1 - 0.11 12.5 4.8 0.064 13.1 0.7 2.7 2 1 0 2 2 2 0 Phage shock protein B Pro_isomerase PF00160.16 GAO90794.1 - 3.9e-41 140.8 0.1 4.7e-41 140.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ctr PF04145.10 GAO90795.1 - 3.4e-48 163.3 1.2 4.3e-48 163.0 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 GAO90795.1 - 0.035 13.6 0.9 0.58 9.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Sensor PF13796.1 GAO90795.1 - 0.39 10.2 3.5 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Putative sensor DUF4407 PF14362.1 GAO90795.1 - 0.69 8.8 3.0 1.3 7.9 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nepo_coat_C PF03688.9 GAO90795.1 - 1.1 8.8 5.8 12 5.5 0.0 2.6 2 1 0 2 2 2 0 Nepovirus coat protein, C-terminal domain RNase_PH PF01138.16 GAO90796.1 - 1.2e-33 116.2 0.4 2.4e-33 115.2 0.2 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 GAO90796.1 - 0.032 14.7 3.1 0.032 14.7 2.1 1.7 2 0 0 2 2 2 0 Coiled coil SNF2_N PF00176.18 GAO90797.1 - 4.4e-54 183.2 0.0 6.7e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 GAO90797.1 - 2.7e-28 97.6 0.6 6.5e-28 96.4 0.4 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 GAO90797.1 - 1e-15 57.3 0.0 2.9e-14 52.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAO90797.1 - 0.0015 17.4 0.0 0.004 16.0 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 GAO90797.1 - 0.0058 16.4 0.1 0.12 12.2 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Ssu72 PF04722.8 GAO90798.1 - 2.4e-84 281.5 0.0 2.8e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein CAP_N PF01213.14 GAO90798.1 - 6 6.0 12.1 10 5.2 8.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Isochorismatase PF00857.15 GAO90799.1 - 2.7e-24 86.0 0.0 6.9e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.3 GAO90800.1 - 3.9e-67 225.0 0.9 4.9e-67 224.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF4116 PF13475.1 GAO90800.1 - 0.011 15.2 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Oxysterol_BP PF01237.13 GAO90801.1 - 5e-89 298.2 0.0 6.7e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.14 GAO90802.1 - 1.8e-77 260.7 0.1 2.3e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PEP_mutase PF13714.1 GAO90803.1 - 1.9e-49 168.0 1.8 2.4e-49 167.7 1.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAO90803.1 - 5.8e-22 77.5 0.6 7.5e-22 77.2 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 GAO90803.1 - 0.077 12.0 0.4 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase AF-4 PF05110.8 GAO90804.1 - 1.9 6.2 8.4 2.5 5.8 5.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tom37_C PF11801.3 GAO90805.1 - 2.2e-46 157.7 0.0 4.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 GAO90805.1 - 2.7e-27 94.8 0.5 3.5e-26 91.2 0.1 2.7 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 GAO90805.1 - 4e-05 23.4 0.0 0.00014 21.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAO90805.1 - 0.0046 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zip PF02535.17 GAO90807.1 - 6e-56 189.7 7.5 6.8e-56 189.5 5.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 GAO90807.1 - 0.11 12.3 0.6 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FKBP_C PF00254.23 GAO90808.1 - 5e-35 119.4 0.0 5.9e-35 119.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 GAO90809.1 - 4.4e-14 52.0 0.0 6.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PP2C PF00481.16 GAO90810.1 - 6.8e-41 140.3 0.1 8.2e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAO90810.1 - 1.1e-06 28.2 0.0 1.4e-05 24.5 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAO90810.1 - 0.0013 18.5 0.6 0.25 11.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) TPM PF04536.9 GAO90810.1 - 0.11 12.3 0.6 5.7 6.8 0.1 2.6 3 0 0 3 3 3 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase UvrD_C PF13361.1 GAO90811.1 - 5.1e-75 253.1 0.0 2.8e-74 250.6 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 GAO90811.1 - 7.8e-62 209.3 0.3 7.7e-60 202.8 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain FmdA_AmdA PF03069.10 GAO90811.1 - 8.8e-52 176.0 0.0 1.3e-25 89.8 0.0 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family UvrD_C_2 PF13538.1 GAO90811.1 - 5.4e-14 52.1 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAO90811.1 - 1.1e-12 47.5 0.3 4.1e-11 42.4 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 GAO90811.1 - 5.1e-05 22.9 0.1 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 GAO90811.1 - 0.00038 19.8 0.0 0.0051 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAO90811.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAO90811.1 - 0.0057 16.8 0.4 3.5 7.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF4158 PF13700.1 GAO90811.1 - 0.017 14.5 0.2 0.11 11.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) AAA_16 PF13191.1 GAO90811.1 - 0.11 12.4 1.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 GAO90811.1 - 0.16 11.1 0.2 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Cyclin_N PF00134.18 GAO90812.1 - 1.4e-34 118.3 0.2 3.2e-34 117.2 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAO90812.1 - 1.4e-13 50.8 0.4 2.6e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain WD40 PF00400.27 GAO90813.1 - 6.9e-14 51.1 10.3 0.12 12.3 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Jacalin PF01419.12 GAO90814.1 - 0.0052 16.6 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 Jacalin-like lectin domain F-box-like PF12937.2 GAO90814.1 - 0.0065 16.1 0.2 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAO90814.1 - 0.033 13.8 0.1 0.084 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain Metallophos PF00149.23 GAO90815.1 - 2.4e-41 141.3 0.2 3.1e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Memo PF01875.12 GAO90816.1 - 1e-65 221.4 0.0 1.4e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Metallophos PF00149.23 GAO90816.1 - 9.8e-21 74.0 3.9 1.8e-20 73.1 2.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAO90816.1 - 1.3e-13 50.8 0.2 3e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAO90816.1 - 8.4e-06 24.6 0.0 1.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAO90816.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_71 PF03659.9 GAO90817.1 - 6.3e-146 485.7 4.7 7.2e-146 485.5 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Rad4 PF03835.10 GAO90819.1 - 4.4e-14 52.0 5.6 9.7e-14 50.9 3.9 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 GAO90819.1 - 1.7e-11 44.3 1.6 4.3e-11 43.0 1.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1180 PF06679.7 GAO90819.1 - 0.43 10.4 3.6 1.2 9.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_transf_20 PF00982.16 GAO90820.1 - 7.9e-198 657.7 0.0 9e-198 657.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 GAO90820.1 - 0.0048 16.3 0.3 4.1 6.7 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferases group 1 Nepo_coat_N PF03689.10 GAO90820.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Glyco_transf_20 PF00982.16 GAO90821.1 - 8.6e-154 512.5 0.0 1.3e-153 511.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAO90821.1 - 1.6e-28 99.1 0.0 3.1e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase MBA1 PF07961.6 GAO90821.1 - 0.048 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 MBA1-like protein WD40 PF00400.27 GAO90822.1 - 2.5e-30 103.2 8.7 1.8e-07 30.7 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat HIRA_B PF09453.5 GAO90822.1 - 9.4e-08 31.4 0.7 4e-07 29.4 0.5 2.2 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 GAO90822.1 - 8.8e-06 25.5 0.6 0.022 14.4 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 GAO90822.1 - 0.0012 17.7 0.0 0.071 11.8 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 GAO90822.1 - 0.018 14.6 2.3 6.5 6.5 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Oxidored_FMN PF00724.15 GAO90825.1 - 3.8e-96 322.0 0.0 4.3e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 GAO90825.1 - 0.0047 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Tautomerase enzyme Grp1_Fun34_YaaH PF01184.14 GAO90826.1 - 1.2e-87 292.6 16.7 1.5e-87 292.3 11.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.4 GAO90826.1 - 2.7 7.3 5.1 9.8 5.5 3.6 1.9 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Fungal_trans_2 PF11951.3 GAO90827.1 - 5.4e-10 38.4 0.7 3e-09 35.9 0.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain ANTH PF07651.11 GAO90828.1 - 1.8e-62 210.5 0.8 2.2e-62 210.2 0.6 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 GAO90828.1 - 3.3e-07 30.2 0.1 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.6 GAO90828.1 - 1 9.4 137.1 0.047 13.7 26.9 5.1 2 1 3 5 5 5 0 Domain of unknown function (DUF1720) Nucleoplasmin PF03066.10 GAO90829.1 - 0.077 12.5 3.5 0.14 11.6 2.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_S17 PF00366.15 GAO90830.1 - 9.3e-31 105.6 0.9 1.5e-30 105.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 GAO90831.1 - 0 1250.2 66.5 0 1250.2 46.1 2.4 3 0 0 3 3 3 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 GAO90831.1 - 2.8e-131 437.0 4.3 4.9e-131 436.2 3.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 GAO90831.1 - 0.16 11.5 15.3 0.69 9.4 10.6 2.0 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 GAO90831.1 - 3.2 6.7 3.4 6.3 5.7 2.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Fungal_trans PF04082.13 GAO90832.1 - 8.8e-30 103.4 0.5 1.8e-29 102.4 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90832.1 - 0.029 14.2 12.1 0.053 13.4 8.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 GAO90833.1 - 3.2e-13 49.0 1.6 3.2e-13 49.0 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) DUF3295 PF11702.3 GAO90834.1 - 2e-217 723.1 27.0 2.3e-217 722.9 18.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 GAO90834.1 - 5.8e-12 44.9 2.4 1.2e-11 43.9 1.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-CHY PF05495.7 GAO90835.1 - 2.4e-13 50.0 10.7 2.4e-13 50.0 7.4 3.4 3 0 0 3 3 3 2 CHY zinc finger zf-DNA_Pol PF08996.5 GAO90835.1 - 0.0048 16.2 3.9 0.38 10.0 0.5 2.5 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger Cir_N PF10197.4 GAO90835.1 - 0.1 12.6 0.2 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR SIR2 PF02146.12 GAO90835.1 - 0.14 11.8 0.5 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Sir2 family Glyoxalase PF00903.20 GAO90836.1 - 2.9e-20 72.5 0.5 7.7e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAO90836.1 - 2.7e-14 53.0 0.1 5.1e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAO90836.1 - 1.1e-08 35.6 0.1 0.0015 19.0 0.0 2.8 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 GAO90836.1 - 6e-06 26.2 0.0 0.098 12.5 0.0 3.5 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAO90836.1 - 0.00013 21.8 0.0 0.0042 17.0 0.0 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 GAO90837.1 - 0.028 14.0 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 TPR repeat HgmA PF04209.8 GAO90838.1 - 7.8e-195 647.1 0.1 8.9e-195 647.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 GAO90839.1 - 2e-48 164.7 0.0 2.6e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAO90839.1 - 2e-25 88.8 0.0 5.4e-25 87.4 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.1 GAO90840.1 - 3.6e-12 46.3 0.1 6.1e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAO90840.1 - 8.7e-10 38.4 0.1 2e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAO90840.1 - 1.8e-07 31.1 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAO90840.1 - 2.6e-05 24.1 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAO90840.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 GAO90841.1 - 1.2e-06 28.3 7.0 2.1e-06 27.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 GAO90842.1 - 2.5e-34 118.0 6.9 3.1e-34 117.7 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 GAO90842.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal UPF0126 PF03458.8 GAO90842.1 - 4.2 7.0 8.0 19 4.9 0.0 3.1 1 1 3 4 4 4 0 UPF0126 domain Asparaginase_2 PF01112.13 GAO90843.1 - 1.1e-40 139.3 0.0 1.1e-17 63.7 0.0 3.4 3 0 0 3 3 3 3 Asparaginase p450 PF00067.17 GAO90844.1 - 3.5e-76 256.6 0.0 4.1e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAO90845.1 - 3.8e-24 85.0 41.9 3.5e-23 81.8 29.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAO90845.1 - 4.4e-08 32.1 15.5 4.4e-08 32.1 10.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAO90845.1 - 1.3e-07 30.2 16.9 1.6e-07 29.9 11.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RTA1 PF04479.8 GAO90846.1 - 4.1e-40 137.6 4.8 4.1e-40 137.6 3.3 1.6 2 0 0 2 2 2 1 RTA1 like protein Abhydrolase_3 PF07859.8 GAO90847.1 - 1.5e-28 99.7 0.6 2.2e-28 99.2 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAO90847.1 - 1.2e-14 53.7 0.0 4.2e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAO90847.1 - 2.3e-05 24.2 0.1 3.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAO90847.1 - 0.00093 19.1 3.2 0.0029 17.5 0.8 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAO90847.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 GAO90847.1 - 0.019 15.1 0.5 0.034 14.3 0.3 1.4 1 0 0 1 1 1 0 Thioesterase domain PAE PF03283.8 GAO90847.1 - 0.089 11.4 0.0 9.6 4.7 0.0 2.2 2 0 0 2 2 2 0 Pectinacetylesterase Lipase_3 PF01764.20 GAO90847.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 GAO90847.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Arginosuc_synth PF00764.14 GAO90848.1 - 3.8e-156 520.0 0.0 4.4e-156 519.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 GAO90848.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 GAO90848.1 - 9.7e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 GAO90848.1 - 0.0037 15.8 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Oxidored_FMN PF00724.15 GAO90849.1 - 3.6e-67 226.7 0.0 4.3e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 GAO90849.1 - 0.0037 16.1 0.0 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) PT PF04886.7 GAO90850.1 - 0.095 12.0 4.8 0.082 12.2 1.8 2.1 2 0 0 2 2 2 0 PT repeat Peptidase_M20 PF01546.23 GAO90851.1 - 2.4e-24 85.9 0.0 6.1e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 GAO90851.1 - 9.2e-12 44.3 10.1 0.016 15.0 0.0 6.3 5 1 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 GAO90851.1 - 6.2e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAO90851.1 - 0.0046 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PQQ_3 PF13570.1 GAO90851.1 - 1.4 9.2 6.7 23 5.4 0.0 4.9 4 1 1 5 5 5 0 PQQ-like domain Methyltransf_23 PF13489.1 GAO90852.1 - 9.6e-11 41.6 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90852.1 - 7e-09 36.2 0.0 1.6e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90852.1 - 4.7e-08 32.7 0.0 1.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90852.1 - 5.7e-08 33.1 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90852.1 - 8.1e-07 29.0 0.0 2.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90852.1 - 4.4e-06 27.0 0.0 9.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90852.1 - 0.00034 20.9 0.0 0.00076 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAO90852.1 - 0.12 13.1 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF747 PF05346.6 GAO90853.1 - 1.1e-131 438.8 6.4 1.3e-131 438.5 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Cas_TM1802 PF09484.5 GAO90854.1 - 0.37 9.2 0.0 0.51 8.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) DUF2199 PF09965.4 GAO90855.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) DUF21 PF01595.15 GAO90856.1 - 4.8e-32 110.7 0.2 7.7e-32 110.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAO90856.1 - 5.6e-07 29.2 0.5 0.014 15.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain zf-C2H2_2 PF12756.2 GAO90857.1 - 3.1e-38 129.9 17.9 4.6e-32 110.1 3.1 3.4 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 GAO90857.1 - 8e-09 35.4 12.9 1.4e-06 28.2 3.6 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAO90857.1 - 3.3e-06 27.0 12.9 4.1e-06 26.8 3.4 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAO90857.1 - 0.0001 22.0 1.8 0.17 11.8 0.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.6 GAO90857.1 - 0.026 14.2 0.6 0.026 14.2 0.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF2024 PF09630.5 GAO90857.1 - 0.034 13.8 2.5 0.25 11.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2 PF00096.21 GAO90857.1 - 0.053 13.8 23.6 0.23 11.9 0.2 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF629 PF04780.7 GAO90857.1 - 0.71 8.3 7.3 0.35 9.3 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF629) HECT PF00632.20 GAO90858.1 - 7.6e-78 261.8 0.0 1.2e-77 261.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) His_Phos_1 PF00300.17 GAO90859.1 - 1.2e-13 51.3 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Borrelia_P83 PF05262.6 GAO90860.1 - 8.5 4.5 8.3 13 3.9 5.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 GAO90860.1 - 8.7 4.2 6.9 12 3.7 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_43 PF04616.9 GAO90861.1 - 3.8e-44 150.9 1.8 6.9e-44 150.0 1.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 2-Hacid_dh_C PF02826.14 GAO90862.1 - 8e-55 184.7 0.0 1.3e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAO90862.1 - 9.3e-36 122.2 0.2 1.5e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 GAO90862.1 - 0.00039 20.0 0.8 0.032 13.8 0.2 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 GAO90862.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 GAO90862.1 - 0.0084 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DAO PF01266.19 GAO90862.1 - 0.01 14.7 1.8 1.2 7.9 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.7 GAO90862.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 GAO90862.1 - 0.016 14.6 2.3 0.052 13.0 0.0 3.0 4 0 0 4 4 4 0 ACT domain NAD_binding_2 PF03446.10 GAO90862.1 - 0.035 13.9 0.1 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 GAO90863.1 - 9.1e-08 31.8 10.6 1.7e-07 31.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRIC_ras_sig PF10534.4 GAO90863.1 - 0.0021 18.0 0.3 0.72 9.9 0.0 2.7 2 0 0 2 2 2 2 Connector enhancer of kinase suppressor of ras PT-VENN PF04829.8 GAO90863.1 - 0.032 13.7 0.7 0.099 12.2 0.5 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Fe-ADH PF00465.14 GAO90864.1 - 6.8e-105 350.6 0.0 9e-105 350.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAO90864.1 - 1.8e-15 56.9 0.0 8.1e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 GAO90864.1 - 0.00018 20.9 0.1 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 GAO90864.1 - 0.076 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Arylsulfotran_2 PF14269.1 GAO90865.1 - 1.7e-106 355.7 5.2 3.1e-106 354.8 3.6 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAO90865.1 - 4.4e-14 51.8 0.8 1.9e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Sugar_tr PF00083.19 GAO90866.1 - 5.1e-104 348.3 30.9 6.3e-104 348.0 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90866.1 - 1.9e-21 76.1 33.5 3e-21 75.5 19.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 GAO90866.1 - 8e-15 55.1 2.2 1e-14 54.7 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAO90866.1 - 8.6e-07 28.7 0.1 3.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAO90866.1 - 0.0013 18.8 0.1 0.0045 17.0 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase BNR_2 PF13088.1 GAO90867.1 - 3.6e-06 26.4 0.0 3.5e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 BNR repeat-like domain BNR PF02012.15 GAO90867.1 - 0.0003 20.1 4.9 0.11 12.4 0.1 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat ADH_zinc_N PF00107.21 GAO90868.1 - 6.8e-25 87.1 1.2 9.9e-25 86.5 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAO90868.1 - 3.1e-21 75.1 0.6 7.1e-21 74.0 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAO90868.1 - 5.3e-07 30.5 0.0 9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 GAO90869.1 - 3.6e-07 29.9 8.9 7.7e-07 28.9 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO90869.1 - 0.00028 19.8 0.0 0.00054 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF336 PF03928.9 GAO90870.1 - 2e-14 53.5 0.7 1.5e-13 50.6 0.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF336) HSP70 PF00012.15 GAO90871.1 - 1e-266 885.7 13.4 1.1e-266 885.5 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAO90871.1 - 3.3e-18 65.3 1.6 4.7e-17 61.5 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 GAO90871.1 - 0.007 15.2 1.0 0.034 12.9 0.7 2.0 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 GAO90871.1 - 0.11 11.5 6.6 0.43 9.6 0.1 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 GAO90871.1 - 2.8 7.7 6.5 3.1 7.6 0.2 3.4 2 1 0 2 2 2 0 Cell division protein FtsA GTP_EFTU PF00009.22 GAO90872.1 - 8.4e-50 168.8 0.0 1.3e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 GAO90872.1 - 3.7e-15 55.8 1.8 7.4e-15 54.8 1.3 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 GAO90872.1 - 7.3e-09 35.6 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO90872.1 - 8.7e-08 32.1 0.0 2.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 GAO90872.1 - 1.9e-07 31.1 0.0 8.4e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Gtr1_RagA PF04670.7 GAO90872.1 - 7.7e-05 21.9 0.0 0.0002 20.5 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAO90872.1 - 0.0055 17.1 0.1 0.027 14.9 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 GAO90872.1 - 0.0084 15.3 0.0 0.57 9.3 0.0 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAO90872.1 - 0.017 14.4 0.2 1.2 8.3 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.9 GAO90872.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Siah-Interact_N PF09032.6 GAO90872.1 - 0.083 12.9 0.7 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal UCH_1 PF13423.1 GAO90873.1 - 1.9e-69 234.3 0.8 2.5e-69 233.9 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 GAO90873.1 - 1.4e-21 77.4 0.0 3.1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 GAO90873.1 - 5.6e-07 28.9 0.0 4e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 GAO90874.1 - 3e-70 236.3 0.0 5.3e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAO90874.1 - 5.8e-45 153.3 0.0 1.2e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase VHS PF00790.14 GAO90874.1 - 4.4e-35 120.3 0.6 8.3e-35 119.4 0.4 1.4 1 0 0 1 1 1 1 VHS domain PBD PF00786.23 GAO90874.1 - 3e-20 72.3 1.0 1.5e-19 70.1 0.0 2.9 2 0 0 2 2 2 1 P21-Rho-binding domain SH3_1 PF00018.23 GAO90874.1 - 6.8e-16 57.3 0.1 1.6e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAO90874.1 - 2.9e-15 55.5 0.1 5.5e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAO90874.1 - 1.5e-14 53.1 0.0 3.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 GAO90874.1 - 2.1e-06 26.9 0.0 4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Transp_cyt_pur PF02133.10 GAO90875.1 - 1e-18 67.1 31.8 1.9e-18 66.2 22.0 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin KH_1 PF00013.24 GAO90876.1 - 7.2e-93 304.2 22.3 3.5e-12 45.7 0.4 13.9 14 1 0 14 14 14 9 KH domain KH_3 PF13014.1 GAO90876.1 - 1.7e-66 218.9 23.1 3.7e-09 36.0 0.6 13.3 13 1 0 13 13 13 10 KH domain SLS PF14611.1 GAO90876.1 - 3.7e-16 59.1 0.2 0.023 14.1 0.0 7.8 6 3 2 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 GAO90876.1 - 3.7e-12 45.6 22.0 0.042 13.4 0.0 7.9 6 1 1 7 7 7 6 KH domain KH_4 PF13083.1 GAO90876.1 - 0.00015 21.3 6.2 1.5 8.5 0.0 5.1 5 0 0 5 5 5 2 KH domain KH_5 PF13184.1 GAO90876.1 - 0.0071 16.1 6.4 38 4.1 0.1 6.1 6 0 0 6 6 6 0 NusA-like KH domain Cyt-b5 PF00173.23 GAO90877.1 - 8.6e-26 89.5 0.0 1.1e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 GAO90877.1 - 0.043 13.7 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 YqzH-like protein UCH PF00443.24 GAO90878.1 - 1e-55 188.7 0.0 1.5e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAO90878.1 - 1.8e-30 106.4 0.0 2.7e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 GAO90878.1 - 1.2e-06 28.4 0.2 3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 GAO90878.1 - 0.002 18.4 0.0 0.0053 17.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain RNA_pol_Rpb1_4 PF05000.12 GAO90878.1 - 0.088 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 VHS PF00790.14 GAO90879.1 - 2.7e-42 143.7 1.1 2.5e-41 140.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 GAO90879.1 - 1.1e-16 60.4 0.9 1.8e-16 59.7 0.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 GAO90879.1 - 0.00023 20.4 11.2 0.0034 16.8 1.2 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 GAO90879.1 - 0.0059 16.0 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase FYVE_2 PF02318.11 GAO90879.1 - 0.021 14.7 0.2 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 GAO90879.1 - 0.085 12.6 2.5 0.16 11.6 1.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TCO89 PF10452.4 GAO90880.1 - 0.68 8.7 0.0 0.68 8.7 0.0 4.1 2 2 1 3 3 3 0 TORC1 subunit TCO89 RCC1 PF00415.13 GAO90881.1 - 7.2e-24 83.7 1.5 8.5e-08 32.2 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAO90881.1 - 4.9e-15 55.4 0.0 3.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 GAO90881.1 - 1.4e-09 37.2 11.4 2.5e-09 36.5 0.3 4.4 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 GAO90881.1 - 1.9e-07 31.3 0.0 0.0011 19.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAO90881.1 - 0.0035 17.6 0.1 0.078 13.3 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAO90881.1 - 0.0036 17.3 0.0 0.74 10.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 GAO90881.1 - 0.012 15.3 0.0 0.26 11.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 GAO90881.1 - 0.016 15.4 0.0 0.85 9.9 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATG13 PF10033.4 GAO90882.1 - 4.3e-77 258.6 0.0 6.8e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 NUC153 PF08159.7 GAO90883.1 - 3.1e-14 52.2 1.6 7.9e-14 50.9 1.1 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 GAO90883.1 - 2.4e-07 30.3 0.0 0.015 15.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Med13_C PF06333.7 GAO90884.1 - 1.7e-122 409.0 0.0 3.8e-122 407.8 0.0 1.5 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 GAO90884.1 - 2.8e-97 325.9 0.0 4.2e-97 325.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal WGG PF10273.4 GAO90885.1 - 6.1e-31 106.3 0.1 6.1e-31 106.3 0.0 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 SBP_bac_11 PF13531.1 GAO90885.1 - 0.039 13.5 0.1 0.059 12.9 0.1 1.3 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein NOA36 PF06524.7 GAO90885.1 - 0.059 12.6 1.1 0.074 12.3 0.7 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 GAO90885.1 - 0.096 11.8 1.5 0.12 11.4 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 GAO90885.1 - 0.099 12.4 1.6 0.15 11.8 1.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 GAO90885.1 - 0.13 10.4 3.5 0.16 10.1 2.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Vfa1 PF08432.5 GAO90885.1 - 0.25 11.3 2.3 0.33 10.9 1.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ANAPC15 PF15243.1 GAO90885.1 - 0.27 11.3 8.8 0.58 10.2 6.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 FAM176 PF14851.1 GAO90885.1 - 0.36 10.5 2.8 0.63 9.7 1.9 1.4 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.1 GAO90885.1 - 0.38 10.9 5.9 0.8 9.8 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ribosomal_60s PF00428.14 GAO90885.1 - 0.47 10.8 10.1 1 9.8 7.0 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 GAO90885.1 - 1.6 9.1 11.4 0.39 11.0 5.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 GAO90885.1 - 8.2 6.7 13.6 1.4 9.1 6.1 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GTP_EFTU PF00009.22 GAO90886.1 - 2e-43 148.0 0.0 3.2e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAO90886.1 - 9.8e-21 73.7 0.0 2.3e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAO90886.1 - 3.5e-07 30.2 0.3 9.5e-07 28.8 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAO90886.1 - 0.0013 18.6 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAO90886.1 - 0.012 14.2 0.2 0.022 13.4 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit PAT1 PF09770.4 GAO90886.1 - 7.3 4.6 24.1 10 4.2 16.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ran-binding PF05508.6 GAO90887.1 - 3.6e-118 393.8 0.5 4.8e-118 393.4 0.4 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.12 GAO90888.1 - 9.1e-18 63.7 1.3 2.4e-17 62.4 0.9 1.8 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 GAO90888.1 - 1 9.0 8.3 0.21 11.2 3.3 1.7 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Rad4 PF03835.10 GAO90889.1 - 2.2e-36 124.4 1.3 5.5e-36 123.1 0.0 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAO90889.1 - 5.8e-29 99.6 0.0 1.8e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAO90889.1 - 2.2e-20 71.9 0.1 4.8e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAO90889.1 - 4.4e-17 62.1 0.0 1.8e-16 60.2 0.0 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAO90889.1 - 0.0085 16.2 0.3 0.044 13.9 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily E1_dh PF00676.15 GAO90890.1 - 1.6e-108 361.9 0.1 2.1e-108 361.6 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF77 PF01910.12 GAO90890.1 - 1.9e-23 81.9 0.0 3.4e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF77 Methyltransf_23 PF13489.1 GAO90890.1 - 1.3e-21 77.0 0.0 3.1e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90890.1 - 4.8e-10 39.2 0.0 1.9e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO90890.1 - 1.4e-09 38.5 0.0 2e-08 34.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90890.1 - 1.4e-08 35.0 0.0 1.3e-07 31.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90890.1 - 6.3e-07 29.8 0.0 3.2e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90890.1 - 1.8e-05 24.9 0.0 0.00016 21.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAO90890.1 - 7.3e-05 21.9 0.0 0.00021 20.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAO90890.1 - 0.0013 18.7 0.0 0.0052 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DXP_synthase_N PF13292.1 GAO90890.1 - 0.0019 17.1 0.0 0.0041 16.1 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Methyltransf_16 PF10294.4 GAO90890.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 GAO90890.1 - 0.031 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 GAO90890.1 - 0.033 13.2 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DUF2680 PF10925.3 GAO90890.1 - 0.046 13.6 4.9 0.39 10.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Proteasome PF00227.21 GAO90892.1 - 4.2e-46 156.6 0.0 5.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 GAO90892.1 - 1.9e-15 55.8 0.7 4.4e-15 54.6 0.5 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Nucleoporin_FG PF13634.1 GAO90893.1 - 0.06 13.5 0.1 0.06 13.5 0.1 6.1 3 1 1 4 4 4 0 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 GAO90893.1 - 0.69 9.7 3.4 1.7 8.4 2.3 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MEKHLA PF08670.6 GAO90894.1 - 0.00051 19.5 0.1 0.0041 16.6 0.0 2.3 2 1 1 3 3 3 1 MEKHLA domain ABM PF03992.11 GAO90894.1 - 0.0013 18.7 0.5 1.5 8.8 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF3416 PF11896.3 GAO90894.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) KH_1 PF00013.24 GAO90895.1 - 2.9e-44 148.5 2.1 3.1e-16 58.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAO90895.1 - 5.4e-31 105.7 10.8 4.9e-11 42.0 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAO90895.1 - 1.1e-12 47.2 2.6 0.0038 16.7 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAO90895.1 - 5.5e-05 22.7 0.2 1.2 8.8 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 GAO90895.1 - 0.0029 17.3 7.0 0.97 9.2 0.1 3.2 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 GAO90896.1 - 0.00091 18.5 1.9 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Centromere-associated protein K Sec2p PF06428.6 GAO90896.1 - 1.4 8.8 10.8 8.2 6.3 1.6 3.4 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Spc42p PF11544.3 GAO90896.1 - 1.7 8.6 7.8 0.41 10.6 0.1 3.1 3 1 1 4 4 4 0 Spindle pole body component Spc42p Viral_P18 PF04521.8 GAO90896.1 - 8.5 5.8 9.9 1.8 8.0 0.5 3.2 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DEAD PF00270.24 GAO90897.1 - 4.6e-23 81.5 0.1 4e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO90897.1 - 1e-22 79.7 0.1 6.5e-19 67.5 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 GAO90897.1 - 6.9e-17 61.0 0.0 1.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 GAO90897.1 - 9e-09 34.9 0.0 2.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Kelch_3 PF13415.1 GAO90898.1 - 9.5e-31 105.2 15.7 6.9e-11 41.9 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain DUF4110 PF13422.1 GAO90898.1 - 6e-30 102.9 0.4 6e-30 102.9 0.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 GAO90898.1 - 4.6e-24 83.9 19.0 4.8e-07 29.4 0.0 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 GAO90898.1 - 3.8e-18 64.8 5.4 0.0013 18.8 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 GAO90898.1 - 8.6e-17 60.6 3.5 4.1e-05 23.4 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAO90898.1 - 1.7e-15 56.0 7.2 0.0013 18.4 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAO90898.1 - 1.9e-14 52.9 0.0 4.7e-05 22.8 0.0 5.5 5 0 0 5 5 5 3 Kelch motif CENP-B_dimeris PF09026.5 GAO90898.1 - 1.5 9.1 16.7 2.9 8.1 9.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pyridoxal_deC PF00282.14 GAO90899.1 - 1.8e-27 95.7 0.0 3.4e-27 94.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAO90899.1 - 2.4e-05 23.6 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 GAO90899.1 - 0.013 14.0 0.0 0.028 12.9 0.0 1.5 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 GAO90899.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RWP-RK PF02042.10 GAO90899.1 - 0.085 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RWP-RK domain Aminotran_5 PF00266.14 GAO90899.1 - 0.13 11.0 0.0 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Abhydrolase_6 PF12697.2 GAO90900.1 - 3.7e-09 36.7 0.0 1.1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAO90900.1 - 2e-08 34.0 0.0 2.5e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAO90900.1 - 9.8e-08 31.8 0.0 3.4e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAO90900.1 - 0.014 14.6 0.0 0.12 11.6 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 GAO90900.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 GAO90900.1 - 0.06 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Mon1 PF03164.9 GAO90901.1 - 1e-96 324.1 0.0 3.1e-91 306.0 0.0 2.1 1 1 1 2 2 2 2 Trafficking protein Mon1 Dopey_N PF04118.9 GAO90902.1 - 1.4e-122 408.3 0.0 3.6e-122 406.9 0.0 1.7 1 0 0 1 1 1 1 Dopey, N-terminal zf-HIT PF04438.11 GAO90903.1 - 1.3e-09 37.5 12.5 2.1e-09 36.8 8.7 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2360 PF10152.4 GAO90903.1 - 0.65 10.2 4.9 0.98 9.6 3.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2413 PF10310.4 GAO90903.1 - 2.9 6.6 8.3 3.6 6.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MBOAT PF03062.14 GAO90904.1 - 5e-44 150.7 19.5 5.4e-43 147.3 13.5 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family AOX PF01786.12 GAO90905.1 - 1.9e-94 314.8 0.0 2.3e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase KAR9 PF08580.5 GAO90907.1 - 5.7e-164 547.0 0.3 5.7e-164 547.0 0.2 2.0 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Acetyltransf_1 PF00583.19 GAO90908.1 - 0.00019 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAO90908.1 - 0.00098 19.2 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAO90908.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAO90908.1 - 0.03 14.4 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAO90908.1 - 0.052 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Complex1_LYR PF05347.10 GAO90909.1 - 7.9e-09 35.1 0.1 1.4e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAO90909.1 - 7.2e-08 32.5 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAO90909.1 - 7.4e-06 26.3 0.0 9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 GAO90910.1 - 6.3e-18 64.9 0.2 8.8e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO90910.1 - 0.00024 20.5 0.1 0.00061 19.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAO90910.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 GAO90911.1 - 9.5e-17 60.3 0.0 1.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAO90911.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 GAO90911.1 - 0.1 12.9 6.6 0.17 12.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 GAO90911.1 - 2.3 6.5 13.4 2.8 6.3 9.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) F-box-like PF12937.2 GAO90912.1 - 0.00024 20.7 0.3 0.00089 18.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 GAO90912.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain HNH_2 PF13391.1 GAO90913.1 - 3.9e-11 42.5 0.1 8.2e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease GTP_EFTU PF00009.22 GAO90914.1 - 7e-11 41.9 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 GAO90914.1 - 0.0064 16.4 0.2 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 GAO90914.1 - 0.03 13.8 0.1 0.69 9.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ank_2 PF12796.2 GAO90916.1 - 7e-17 61.5 0.0 1.3e-05 25.4 0.0 4.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAO90916.1 - 7.1e-12 45.5 3.1 0.0022 18.4 0.0 6.3 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAO90916.1 - 7.4e-10 38.7 3.9 0.0027 17.8 0.1 5.7 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.25 GAO90916.1 - 2e-07 30.4 7.3 0.085 12.7 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 GAO90916.1 - 6.6e-05 22.7 6.7 0.016 15.4 0.1 5.8 7 0 0 7 7 7 1 Ankyrin repeat Orthopox_F14 PF06076.7 GAO90916.1 - 0.0084 16.1 1.5 0.18 11.8 0.1 3.3 4 0 0 4 4 4 1 Orthopoxvirus F14 protein Prominin PF05478.6 GAO90916.1 - 0.12 9.9 0.7 0.17 9.3 0.5 1.2 1 0 0 1 1 1 0 Prominin ING PF12998.2 GAO90916.1 - 0.42 10.8 5.1 0.61 10.3 0.8 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding HsbA PF12296.3 GAO90917.1 - 2.4e-32 111.4 10.3 2.4e-32 111.4 7.1 3.5 2 1 2 4 4 4 1 Hydrophobic surface binding protein A LPP PF04728.8 GAO90917.1 - 5.2 6.9 7.8 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper GMC_oxred_N PF00732.14 GAO90918.1 - 3.6e-61 206.9 0.0 4.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAO90918.1 - 4.6e-34 117.7 0.0 8.9e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAO90918.1 - 6.3e-05 22.9 0.0 0.00022 21.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO90918.1 - 0.00018 20.5 0.3 0.0042 16.0 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAO90918.1 - 0.0029 16.7 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAO90918.1 - 0.0031 16.4 0.0 0.0082 15.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAO90918.1 - 0.017 14.0 0.1 0.043 12.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 GAO90918.1 - 0.023 13.1 0.0 0.044 12.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 GAO90918.1 - 0.068 13.0 0.0 1.4 8.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAO90918.1 - 0.13 12.0 0.1 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding SKG6 PF08693.5 GAO90919.1 - 0.0029 16.8 1.0 0.0065 15.7 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 GAO90919.1 - 0.024 14.1 0.3 0.045 13.3 0.2 1.5 1 0 0 1 1 1 0 Podoplanin Herpes_gE PF02480.11 GAO90919.1 - 0.069 11.4 0.0 0.13 10.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AAA_12 PF13087.1 GAO90920.1 - 1.3e-40 138.9 0.0 3.5e-40 137.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAO90920.1 - 4.1e-28 98.5 0.2 1.2e-27 97.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAO90920.1 - 5.6e-09 35.6 0.1 4.4e-08 32.7 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 GAO90920.1 - 9e-05 21.6 0.2 0.18 10.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 GAO90920.1 - 0.00032 20.3 1.3 0.0099 15.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain zf-CCCH PF00642.19 GAO90920.1 - 0.0004 19.9 2.9 0.0004 19.9 2.0 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.10 GAO90920.1 - 0.0036 17.1 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 GAO90920.1 - 0.012 14.9 0.0 0.035 13.4 0.0 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 GAO90920.1 - 0.02 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Zn-ribbon_8 PF09723.5 GAO90920.1 - 8 6.5 7.1 18 5.4 0.5 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Sugar_tr PF00083.19 GAO90921.1 - 9.3e-119 396.9 19.9 1.2e-118 396.5 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAO90921.1 - 2.4e-25 88.9 36.3 3.1e-22 78.7 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAO90921.1 - 0.0025 16.0 2.8 0.0025 16.0 1.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkr1 PF08636.5 GAO90922.1 - 1.1e-35 121.4 6.6 1.5e-35 121.0 4.5 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.8 GAO90922.1 - 0.22 11.9 1.2 1.2 9.5 0.8 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cullin PF00888.17 GAO90923.1 - 1.3e-48 165.9 0.0 5.2e-48 163.9 0.0 1.8 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 GAO90923.1 - 1.9e-23 82.4 0.0 9.1e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TauD PF02668.11 GAO90924.1 - 1.2e-25 90.7 0.3 1.5e-25 90.3 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATase PF00117.23 GAO90925.1 - 0.029 13.8 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Glutamine amidotransferase class-I AAA_12 PF13087.1 GAO90926.1 - 3.4e-05 23.2 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Lactonase PF10282.4 GAO90927.1 - 3.1e-95 319.1 0.1 4e-95 318.8 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 GAO90927.1 - 0.18 11.8 5.7 0.26 11.3 2.0 2.7 2 1 0 2 2 2 0 Putative Ig domain FAD_binding_3 PF01494.14 GAO90929.1 - 6.2e-17 61.6 0.5 2.2e-16 59.8 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAO90929.1 - 3.7e-05 23.6 0.2 0.0003 20.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAO90929.1 - 4.3e-05 22.5 0.2 7.1e-05 21.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAO90929.1 - 0.0024 17.6 0.0 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAO90929.1 - 0.0028 18.0 0.6 0.01 16.2 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAO90929.1 - 0.0029 17.5 0.0 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAO90929.1 - 0.0032 16.3 0.9 0.0059 15.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 GAO90929.1 - 0.0048 15.7 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 GAO90929.1 - 0.0094 14.4 0.1 0.016 13.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 GAO90929.1 - 0.019 14.5 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAO90929.1 - 0.037 14.0 0.3 0.075 13.0 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAO90929.1 - 0.072 11.7 0.6 0.12 11.0 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 GAO90929.1 - 0.083 11.7 0.9 0.13 11.1 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 GAO90929.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 GAO90929.1 - 0.22 10.4 0.6 2.1 7.1 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein F-box-like PF12937.2 GAO90930.1 - 0.0038 16.9 0.9 0.011 15.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAO90930.1 - 0.0058 16.2 0.0 0.021 14.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain NmrA PF05368.8 GAO90931.1 - 2.7e-19 69.3 0.0 3.8e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAO90931.1 - 0.021 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding FAD_binding_4 PF01565.18 GAO90932.1 - 2.9e-25 88.3 0.8 4.4e-25 87.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAO90932.1 - 4.9e-05 23.1 0.1 9.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.13 GAO90933.1 - 1.3e-21 76.6 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90933.1 - 4.9e-05 23.1 7.6 9.1e-05 22.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.19 GAO90934.1 - 4.8e-44 149.3 34.9 2e-22 79.2 9.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro_72 PF03198.9 GAO90935.1 - 3.6e-133 443.3 7.8 4.7e-133 443.0 5.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAO90935.1 - 1.4e-27 96.0 6.7 4.9e-27 94.2 4.6 2.1 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 GAO90935.1 - 2.6e-07 29.8 0.2 4.1e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 GAO90935.1 - 0.0057 15.8 0.9 0.014 14.5 0.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 GAO90936.1 - 2.1e-38 131.9 32.1 2.1e-38 131.9 22.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 GAO90936.1 - 0.079 12.2 0.1 0.079 12.2 0.0 2.6 3 1 0 3 3 3 0 ABC-2 family transporter protein Fungal_trans PF04082.13 GAO90937.1 - 1.8e-24 86.0 0.9 3.1e-24 85.2 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90937.1 - 1.3e-06 28.2 11.9 2.4e-06 27.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAO90938.1 - 6.8e-25 87.4 0.0 1.2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAO90938.1 - 9.4e-08 31.8 15.0 1.9e-07 30.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 GAO90938.1 - 0.32 9.7 4.2 0.33 9.7 1.4 1.9 2 0 0 2 2 2 0 Clusterin DUF3608 PF12257.3 GAO90939.1 - 8.8e-75 251.1 0.0 1.4e-74 250.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 GAO90939.1 - 1.4e-30 104.7 1.3 3.2e-30 103.6 0.9 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UPF0561 PF10573.4 GAO90939.1 - 0.026 14.3 4.2 0.021 14.6 1.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Glyco_hydro_31 PF01055.21 GAO90940.1 - 3.6e-117 391.8 0.3 4.9e-117 391.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAO90940.1 - 4.4e-23 80.9 0.1 2.1e-21 75.5 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like FNIP_N PF14636.1 GAO90941.1 - 5.7e-22 78.5 0.0 5.7e-22 78.5 0.0 4.0 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 GAO90941.1 - 0.0058 16.2 0.0 0.016 14.7 0.0 1.7 1 1 1 2 2 2 1 Folliculin-interacting protein middle domain NUC153 PF08159.7 GAO90942.1 - 6.7e-12 44.7 8.5 2e-11 43.2 0.2 3.7 3 0 0 3 3 3 1 NUC153 domain PRK PF00485.13 GAO90943.1 - 3.7e-54 183.2 0.2 3.2e-34 118.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 GAO90943.1 - 3e-41 140.9 0.0 5.4e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 GAO90943.1 - 2.4e-07 31.6 0.0 8.6e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAO90943.1 - 1.4e-05 25.4 0.0 4.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 GAO90943.1 - 4.1e-05 23.2 0.0 8.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 GAO90943.1 - 0.011 14.7 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 GAO90943.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAO90943.1 - 0.053 13.2 0.3 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 GAO90943.1 - 0.063 13.0 0.2 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 GAO90943.1 - 0.072 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 GAO90943.1 - 0.086 11.5 0.1 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 GAO90943.1 - 0.1 12.3 0.0 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAO90943.1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 GAO90943.1 - 0.11 12.7 0.9 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.4 GAO90944.1 - 3e-34 117.7 0.1 3.8e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAO90944.1 - 1.5e-09 37.3 0.0 2.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 LisH ATP-cone PF03477.11 GAO90944.1 - 0.087 13.2 0.4 2.7 8.4 0.0 2.7 1 1 1 2 2 2 0 ATP cone domain Pyr_redox_2 PF07992.9 GAO90945.1 - 1.3e-19 70.8 0.0 2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAO90945.1 - 2.4e-12 47.0 0.0 1e-10 41.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 GAO90945.1 - 7e-06 24.9 0.1 1.9e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAO90945.1 - 4.5e-05 23.4 0.1 0.00014 21.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAO90945.1 - 5.4e-05 22.7 0.3 0.00017 21.2 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAO90945.1 - 0.00022 20.4 0.3 0.00075 18.7 0.1 2.0 2 0 0 2 2 2 1 EF hand Myc_N PF01056.13 GAO90945.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pyr_redox_3 PF13738.1 GAO90945.1 - 0.045 13.8 0.2 5.6 6.9 0.0 3.2 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cna_B PF05738.8 GAO90945.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Cna protein B-type domain Nipped-B_C PF12830.2 GAO90946.1 - 4.5e-51 173.1 3.3 8.2e-51 172.3 0.3 2.9 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 GAO90946.1 - 1e-11 44.5 2.2 3.7e-11 42.7 1.1 2.4 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 GAO90946.1 - 0.00014 21.7 4.2 0.0024 17.7 0.1 3.7 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAO90946.1 - 0.0015 18.4 3.2 1.4 9.2 0.3 5.2 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.15 GAO90946.1 - 0.031 12.6 8.4 0.034 12.4 2.9 3.1 3 1 1 4 4 4 0 Adaptin N terminal region TFIIS_C PF01096.13 GAO90947.1 - 7.7e-15 54.2 9.8 1.9e-14 53.0 2.0 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAO90947.1 - 7.4e-06 25.5 0.3 7.4e-06 25.5 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 GAO90947.1 - 0.0068 16.2 6.8 0.11 12.3 3.2 2.4 1 1 1 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAO90947.1 - 0.013 14.9 7.8 0.71 9.4 0.0 3.5 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 GAO90947.1 - 0.05 13.2 6.6 0.58 9.8 0.2 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 GAO90947.1 - 0.073 12.4 8.2 0.6 9.4 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding FpoO PF10621.4 GAO90947.1 - 0.088 12.8 0.6 0.22 11.5 0.4 1.7 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO zf-trcl PF13451.1 GAO90947.1 - 0.21 11.2 5.6 7.3 6.3 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-binding domain GFA PF04828.9 GAO90947.1 - 0.23 11.4 5.7 10 6.1 1.8 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 GAO90947.1 - 0.55 10.5 7.8 14 6.0 0.7 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar YhfH PF14149.1 GAO90947.1 - 0.56 10.0 3.0 20 5.0 0.1 2.9 3 0 0 3 3 3 0 YhfH-like protein Ribosomal_S27e PF01667.12 GAO90947.1 - 1.1 8.8 5.5 0.8 9.3 0.2 2.7 2 2 1 3 3 3 0 Ribosomal protein S27 Zn_ribbon_recom PF13408.1 GAO90947.1 - 1.6 9.0 11.7 11 6.4 0.1 3.1 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.9 GAO90947.1 - 1.9 8.2 7.1 2.4 7.9 2.0 2.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.1 GAO90947.1 - 2.6 7.7 7.5 12 5.6 2.4 3.1 2 1 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 GAO90947.1 - 4.2 6.7 12.8 5.6 6.3 2.3 3.3 3 1 1 4 4 4 0 zinc-ribbon domain Rubredoxin PF00301.15 GAO90947.1 - 8.1 6.4 8.8 6.8 6.6 0.6 3.6 3 1 1 4 4 4 0 Rubredoxin NOB1_Zn_bind PF08772.6 GAO90947.1 - 9.3 6.1 9.1 9.8 6.0 0.4 2.9 1 1 2 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like HEAT_2 PF13646.1 GAO90948.1 - 1.1e-34 118.5 1.4 6e-16 58.5 0.0 3.8 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 GAO90948.1 - 1.1e-22 78.1 0.6 0.0041 17.4 0.1 6.2 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 GAO90948.1 - 4e-11 43.0 3.5 0.017 15.6 0.0 5.4 5 2 1 6 6 6 3 HEAT-like repeat HEAT PF02985.17 GAO90948.1 - 2.7e-09 36.3 3.7 1.5 9.0 0.0 6.2 7 0 0 7 7 7 4 HEAT repeat RuvA_C PF07499.8 GAO90948.1 - 0.0029 17.7 0.2 1.5 9.0 0.0 3.6 3 0 0 3 3 3 1 RuvA, C-terminal domain Cohesin_HEAT PF12765.2 GAO90948.1 - 0.014 15.3 1.2 1.9 8.5 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion ETC_C1_NDUFA4 PF04800.7 GAO90949.1 - 1.2e-37 127.8 0.9 1.8e-37 127.2 0.6 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 GAO90950.1 - 1.8e-41 140.2 0.3 2e-41 140.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 GAO90950.1 - 0.065 13.2 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MOZ_SAS PF01853.13 GAO90952.1 - 1.1e-85 285.5 0.1 1.7e-85 285.0 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 GAO90952.1 - 1e-23 82.7 0.0 1.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Myb_Cef PF11831.3 GAO90952.1 - 0.0075 15.5 2.0 0.3 10.2 1.4 2.2 1 1 0 1 1 1 1 pre-mRNA splicing factor component DUF2314 PF10077.4 GAO90952.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) HTH_9 PF08221.6 GAO90952.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Acetyltransf_1 PF00583.19 GAO90952.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Myb_Cef PF11831.3 GAO90953.1 - 1.7e-64 217.2 0.2 1.7e-64 217.2 0.2 3.5 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 GAO90953.1 - 3.6e-20 71.7 4.0 2.6e-09 36.9 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAO90953.1 - 1.2e-19 70.1 4.4 4.3e-13 49.1 0.6 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF3006 PF11213.3 GAO90953.1 - 0.054 13.2 4.3 0.53 10.0 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Vps51 PF08700.6 GAO90953.1 - 2.3 8.1 8.1 3.9 7.3 0.4 3.3 3 0 0 3 3 3 0 Vps51/Vps67 Nop53 PF07767.6 GAO90954.1 - 1.2e-130 436.0 37.1 1.6e-130 435.5 25.7 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FLO_LFY PF01698.11 GAO90954.1 - 0.0093 14.8 17.0 0.021 13.6 11.8 1.5 1 0 0 1 1 1 1 Floricaula / Leafy protein Neur_chan_memb PF02932.11 GAO90954.1 - 0.52 10.1 5.6 1.1 9.0 3.6 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RNase_H2_suC PF08615.6 GAO90955.1 - 5.8e-32 110.3 0.0 5.8e-32 110.3 0.0 2.8 2 1 1 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.19 GAO90955.1 - 4e-27 95.5 0.0 8e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DcpS_C PF11969.3 GAO90956.1 - 2.2e-30 105.2 0.0 3.7e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 GAO90956.1 - 5.5e-27 94.3 0.0 9.5e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Peptidase_C12 PF01088.16 GAO90957.1 - 9.3e-61 204.7 0.0 1.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MT-A70 PF05063.9 GAO90958.1 - 1.2e-22 80.3 0.0 2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Pox_A_type_inc PF04508.7 GAO90958.1 - 0.3 10.9 2.1 0.58 10.0 1.5 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PUF PF00806.14 GAO90959.1 - 1.8e-28 96.3 0.0 1.8e-05 23.9 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 GAO90959.1 - 2.6e-10 39.7 0.0 5.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO90959.1 - 2.5e-07 30.4 0.0 5.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90959.1 - 1.3e-05 25.1 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 GAO90960.1 - 9.2e-63 212.0 23.8 9.2e-63 212.0 16.5 3.1 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 GAO90960.1 - 1.8e-11 43.3 0.2 4.6e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Bin3 PF06859.7 GAO90961.1 - 1.2e-26 92.7 0.0 1.8e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 GAO90961.1 - 1.7e-12 47.9 0.0 3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAO90961.1 - 7.2e-12 45.3 0.0 9.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAO90961.1 - 3.3e-10 39.7 0.0 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAO90961.1 - 2.8e-08 34.1 0.0 4.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAO90961.1 - 1.7e-07 31.5 0.0 3.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAO90961.1 - 2.2e-06 27.6 0.2 6.1e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAO90961.1 - 1.1e-05 25.6 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAO90961.1 - 3e-05 23.4 0.0 7e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 GAO90961.1 - 0.001 18.2 0.2 0.0016 17.6 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 GAO90961.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Glyco_hydro_16 PF00722.16 GAO90962.1 - 1.5e-11 43.9 0.3 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PhrC_PhrF PF11131.3 GAO90964.1 - 0.018 14.5 0.7 0.027 14.0 0.5 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling YopD PF05844.7 GAO90965.1 - 0.0044 16.1 0.1 0.006 15.6 0.1 1.2 1 0 0 1 1 1 1 YopD protein MMS22L_C PF14911.1 GAO90965.1 - 0.032 13.2 0.1 0.038 13.0 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal CCDC32 PF14989.1 GAO90965.1 - 0.11 12.3 0.2 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 tRNA-synt_2 PF00152.15 GAO90966.1 - 9.1e-73 244.9 0.0 1.4e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAO90966.1 - 2.9e-07 30.2 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BcsB PF03170.8 GAO90966.1 - 0.033 12.2 0.0 0.054 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Trypan_glycop PF00913.14 GAO90966.1 - 0.034 13.0 4.9 0.054 12.3 3.4 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) KfrA_N PF11740.3 GAO90966.1 - 0.087 13.2 4.6 0.18 12.2 3.2 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RRM_1 PF00076.17 GAO90967.1 - 1.6e-38 130.1 0.1 6.4e-12 44.9 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90967.1 - 5.2e-38 128.8 0.1 3.5e-09 36.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO90967.1 - 7.3e-18 64.1 0.1 0.00035 20.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 GAO90967.1 - 1.1e-16 60.0 5.4 7.2e-16 57.5 3.8 2.5 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 GAO90967.1 - 1.8e-05 24.4 0.0 0.071 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 GAO90967.1 - 0.023 14.6 0.0 0.59 10.1 0.0 3.1 3 1 0 3 3 3 0 RNA binding domain NID PF07292.8 GAO90967.1 - 0.028 14.4 0.0 0.15 12.1 0.0 2.3 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Spo7_2_N PF15407.1 GAO90967.1 - 0.07 12.6 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 DUF1762 PF08574.5 GAO90968.1 - 4.7e-26 91.0 10.0 4.7e-26 91.0 6.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) DUF3763 PF12592.3 GAO90969.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) RRM_6 PF14259.1 GAO90970.1 - 0.00056 19.8 0.0 0.0049 16.8 0.0 2.5 2 1 1 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pentapeptide_4 PF13599.1 GAO90970.1 - 0.0028 17.4 0.1 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) FTH PF01827.22 GAO90970.1 - 0.13 11.8 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 FTH domain RRM_5 PF13893.1 GAO90970.1 - 0.15 11.9 0.1 0.92 9.4 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP59_mtransfer PF11735.3 GAO90971.1 - 1.5e-83 279.7 0.0 2.2e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SCRG1 PF15224.1 GAO90971.1 - 0.072 12.9 0.4 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 DUF1349 PF07081.6 GAO90972.1 - 4.1e-26 91.4 0.0 5.4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 GAO90973.1 - 6.6e-20 71.1 43.4 1.1e-18 67.0 29.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1435 PF07256.7 GAO90973.1 - 3 7.8 9.0 0.24 11.4 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) Ras PF00071.17 GAO90974.1 - 1.7e-52 177.0 0.0 2e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAO90974.1 - 7.6e-16 58.6 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAO90974.1 - 2.7e-06 26.7 0.0 3.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 GAO90975.1 - 3.7e-91 305.2 0.0 4.5e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAO90975.1 - 0.0055 16.9 0.1 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain ketoacyl-synt PF00109.21 GAO90976.1 - 1.1e-58 198.7 1.8 1.1e-58 198.7 1.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SCA7 PF08313.7 GAO90976.1 - 4.5e-34 115.8 2.0 1.5e-33 114.1 0.4 2.6 3 0 0 3 3 3 1 SCA7, zinc-binding domain Ketoacyl-synt_C PF02801.17 GAO90976.1 - 4.7e-33 113.5 1.7 2.1e-32 111.4 0.7 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAO90976.1 - 2e-06 26.9 0.2 1.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF3505 PF12013.3 GAO90976.1 - 0.066 13.4 0.2 0.24 11.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) CDC45 PF02724.9 GAO90976.1 - 0.24 9.4 6.3 0.35 8.8 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Thiolase_C PF02803.13 GAO90976.1 - 1.1 8.6 5.7 0.55 9.6 0.3 2.9 3 1 0 3 3 3 0 Thiolase, C-terminal domain mRNA_cap_enzyme PF01331.14 GAO90977.1 - 5.3e-51 173.0 0.6 7.9e-51 172.4 0.4 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 GAO90977.1 - 1.4e-22 80.0 0.0 2.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 GAO90977.1 - 5.4e-08 32.4 1.1 1.6e-06 27.6 0.8 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Ribophorin_I PF04597.9 GAO90978.1 - 3e-158 526.8 0.1 3.4e-158 526.7 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I DUF1775 PF07987.6 GAO90978.1 - 0.023 14.5 0.5 5.9 6.7 0.0 3.6 4 0 0 4 4 4 0 Domain of unkown function (DUF1775) Indigoidine_A PF04227.7 GAO90979.1 - 5.5e-114 380.3 0.2 8e-114 379.8 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 GAO90979.1 - 2.5e-22 79.3 0.1 8.4e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MFS_1 PF07690.11 GAO90980.1 - 1.8e-41 142.0 31.5 1.8e-41 142.0 21.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Flavokinase PF01687.12 GAO90980.1 - 2e-35 121.4 0.0 3.1e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Sugar_tr PF00083.19 GAO90980.1 - 4.3e-07 28.8 17.6 7.7e-07 28.0 12.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAO90980.1 - 0.00013 20.3 2.8 0.00022 19.6 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAO90980.1 - 0.032 12.3 0.8 0.21 9.6 1.2 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3918 PF13056.1 GAO90980.1 - 3.4 7.0 4.8 1.3 8.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Rad21_Rec8_N PF04825.8 GAO90981.1 - 7.9e-39 132.0 0.0 1.3e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAO90981.1 - 1.8e-07 30.2 0.1 4.4e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 GAO90981.1 - 0.012 15.1 2.5 0.045 13.3 0.0 2.5 3 0 0 3 3 3 0 ScpA/B protein Spore_coat_CotO PF14153.1 GAO90981.1 - 0.085 12.2 3.1 0.15 11.4 2.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO E1-E2_ATPase PF00122.15 GAO90982.1 - 2.8e-83 278.4 0.4 4.8e-83 277.7 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAO90982.1 - 2e-46 157.8 3.1 2.5e-46 157.5 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAO90982.1 - 4.8e-30 105.5 0.0 9.6e-29 101.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAO90982.1 - 4e-22 77.4 0.1 8.6e-22 76.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAO90982.1 - 1e-14 55.1 0.0 2.7e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAO90982.1 - 3.3e-14 52.6 0.0 6.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAO90982.1 - 6.8e-06 25.8 1.0 6.6e-05 22.6 0.6 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF1192 PF06698.6 GAO90982.1 - 0.18 11.6 3.4 1.9 8.3 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Ammonium_transp PF00909.16 GAO90983.1 - 1.6e-115 385.7 30.5 1.9e-115 385.5 21.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.7 GAO90984.1 - 1.2e-109 366.1 0.0 1.6e-109 365.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein PEP_mutase PF13714.1 GAO90984.1 - 0.025 13.8 0.2 0.052 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase SIR2 PF02146.12 GAO90985.1 - 8.1e-57 191.8 0.0 1.2e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 GAO90985.1 - 0.028 14.1 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF164 PF02591.10 GAO90985.1 - 0.044 13.6 0.5 0.094 12.5 0.3 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Hexokinase_2 PF03727.11 GAO90986.1 - 4.1e-88 294.6 0.0 5.3e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAO90986.1 - 1e-69 234.0 0.2 2.1e-63 213.3 0.0 2.2 1 1 1 2 2 2 2 Hexokinase WD40 PF00400.27 GAO90988.1 - 1.8e-07 30.7 0.4 0.46 10.4 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3661 PF12400.3 GAO90989.1 - 4.4e-43 146.4 3.7 6.7e-43 145.8 2.5 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein Ribosomal_L7Ae PF01248.21 GAO90990.1 - 1e-26 92.2 0.0 1.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 GAO90990.1 - 9.6e-05 22.2 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 GAO90990.1 - 0.057 13.1 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain RRM_1 PF00076.17 GAO90991.1 - 2.5e-19 68.6 0.6 4.5e-19 67.8 0.3 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO90991.1 - 7.9e-14 51.3 0.1 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO90991.1 - 1.6e-10 40.6 0.1 2.6e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAO90991.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif JmjC PF02373.17 GAO90992.1 - 4.4e-09 36.5 0.1 4.7e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 GAO90992.1 - 1.1e-08 34.6 4.8 1.1e-08 34.6 3.3 2.6 3 0 0 3 3 3 1 PHD-finger Cupin_8 PF13621.1 GAO90992.1 - 1.7e-08 34.2 0.0 4.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.1 GAO90992.1 - 0.0007 18.8 2.9 0.0007 18.8 2.0 2.4 3 0 0 3 3 3 1 PHD-finger DUF1423 PF07227.6 GAO90992.1 - 0.29 9.7 1.5 0.52 8.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF946 PF06101.6 GAO90993.1 - 4.8e-14 51.2 0.4 1.3e-13 49.8 0.2 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) TFIIIC_sub6 PF10419.4 GAO90994.1 - 1.1e-15 56.7 0.5 2.1e-15 55.8 0.3 1.5 1 0 0 1 1 1 1 TFIIIC subunit ELFV_dehydrog PF00208.16 GAO90996.1 - 2.1e-60 204.3 0.0 3.9e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Lipase_3 PF01764.20 GAO90996.1 - 1.6e-23 82.8 0.0 4.1e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Bac_GDH PF05088.7 GAO90996.1 - 2.5e-17 61.7 0.0 1.1e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAO90996.1 - 0.0041 16.6 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PPR_3 PF13812.1 GAO90997.1 - 6.4e-09 35.4 1.1 0.22 11.8 0.0 5.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 GAO90997.1 - 0.0026 17.6 1.6 1.1 9.3 0.1 4.5 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 GAO90997.1 - 0.0059 16.5 0.4 35 4.4 0.0 4.4 3 1 2 5 5 5 2 PPR repeat family SAGA-Tad1 PF12767.2 GAO90998.1 - 1.4e-62 211.6 0.0 2.6e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 GAO90998.1 - 4.6e-48 159.4 19.7 9.4e-09 34.8 0.3 11.3 10 1 0 10 10 10 8 WD domain, G-beta repeat FUSC_2 PF13515.1 GAO90998.1 - 1.6e-30 105.6 5.8 1.6e-30 105.6 4.0 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAO90998.1 - 0.0015 18.1 1.4 0.0028 17.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 GAO90998.1 - 0.0021 16.7 22.1 0.016 13.9 0.0 4.0 4 1 0 4 4 4 2 Aluminium activated malate transporter FUSC PF04632.7 GAO90998.1 - 0.029 12.8 17.9 0.039 12.4 0.7 3.2 2 1 0 3 3 3 0 Fusaric acid resistance protein family ATP_bind_1 PF03029.12 GAO90998.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein IKI3 PF04762.7 GAO90998.1 - 0.18 9.5 0.1 2.4 5.8 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PRP1_N PF06424.7 GAO90999.1 - 2.4e-48 163.8 9.0 1.1e-29 103.4 1.5 2.9 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 GAO90999.1 - 1.3e-29 99.9 35.4 7.7e-05 22.9 0.6 14.5 5 3 10 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 GAO90999.1 - 4.5e-25 87.7 19.8 3.3e-06 27.3 0.8 9.8 6 3 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAO90999.1 - 4.2e-23 81.4 23.7 7e-05 23.3 2.7 8.7 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAO90999.1 - 1.2e-14 53.7 13.4 7.9e-06 25.4 0.1 8.0 5 3 4 9 9 9 5 TPR repeat TPR_2 PF07719.12 GAO90999.1 - 3.5e-12 45.2 16.9 0.0057 16.4 0.0 9.2 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAO90999.1 - 5.6e-08 32.0 3.7 0.0085 15.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAO90999.1 - 3.3e-06 26.3 24.8 0.00031 19.8 5.5 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAO90999.1 - 3.6e-06 26.3 1.1 0.97 9.3 0.2 6.7 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAO90999.1 - 2e-05 24.4 8.9 4.9 7.5 0.0 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAO90999.1 - 4.4e-05 23.3 7.5 0.079 12.9 0.0 6.2 6 1 1 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAO90999.1 - 9.9e-05 22.3 1.2 2.6 8.2 0.0 4.6 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.18 GAO90999.1 - 0.007 15.3 6.2 0.7 8.8 0.5 3.4 2 1 1 3 3 3 2 FAT domain Suf PF05843.9 GAO90999.1 - 0.009 15.7 1.4 0.9 9.2 0.0 3.5 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_7 PF13176.1 GAO90999.1 - 0.027 14.2 6.1 49 4.0 0.0 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAO90999.1 - 0.12 12.3 15.6 2.1 8.2 3.9 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.4 GAO90999.1 - 0.15 10.6 1.8 5.5 5.4 0.0 3.8 5 1 1 6 6 6 0 Protein of unknown function (DUF3808) DUF501 PF04417.7 GAO90999.1 - 1.3 8.8 5.7 1.9 8.3 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF501) TPR_6 PF13174.1 GAO90999.1 - 4.6 7.9 17.1 41 4.9 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 GAO91000.1 - 1.3e-48 165.3 0.1 6.4e-48 163.0 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 GAO91001.1 - 6.3e-38 128.2 0.6 7.2e-18 63.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAO91001.1 - 1.1e-29 102.2 0.1 3.6e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAO91001.1 - 7.4e-15 54.5 1.0 1.2e-06 28.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAO91001.1 - 0.00087 19.1 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif MCRS_N PF13325.1 GAO91001.1 - 7.7 5.9 7.4 18 4.7 4.0 2.1 1 1 1 2 2 2 0 N-terminal region of micro-spherule protein TRP PF06011.7 GAO91002.1 - 7.5e-144 479.5 6.6 9.4e-144 479.2 4.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAO91002.1 - 3.6e-42 143.7 1.3 5.7e-42 143.1 0.9 1.3 1 0 0 1 1 1 1 ML-like domain Hep_59 PF07052.6 GAO91003.1 - 9.7e-11 41.9 0.7 9.7e-11 41.9 0.5 3.7 3 2 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 PhaP_Bmeg PF09602.5 GAO91003.1 - 0.099 12.4 0.5 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RNA_polI_A14 PF08203.6 GAO91003.1 - 0.56 10.4 5.0 0.58 10.4 0.1 2.8 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Actin PF00022.14 GAO91004.1 - 3.4e-145 483.4 0.0 3.8e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Actin Fungal_trans PF04082.13 GAO91006.1 - 5.1e-18 64.8 0.1 8.5e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.14 GAO91007.1 - 2.3e-26 92.0 0.1 3.4e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.3 GAO91007.1 - 0.092 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF4228 PF14009.1 GAO91007.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Thioredoxin PF00085.15 GAO91008.1 - 1.2e-65 217.7 5.8 2e-32 110.9 0.0 4.5 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 GAO91008.1 - 9.2e-58 195.0 2.3 8.1e-42 143.1 1.0 3.6 2 2 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.12 GAO91008.1 - 3.1e-14 52.5 3.3 1.7e-13 50.1 2.3 2.0 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 GAO91008.1 - 2e-11 44.1 2.2 0.0017 18.5 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAO91008.1 - 1.8e-10 40.7 0.0 0.0015 18.6 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAO91008.1 - 1.8e-09 37.4 0.0 0.0041 17.1 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 GAO91008.1 - 1.6e-07 30.9 1.5 0.0058 16.3 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 GAO91008.1 - 6.2e-07 29.0 2.4 0.071 12.6 0.0 3.4 3 0 0 3 3 3 3 Redoxin ERp29_N PF07912.8 GAO91008.1 - 0.0022 17.9 0.7 2.8 7.8 0.0 4.3 4 1 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 GAO91008.1 - 0.027 14.2 0.2 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 GAO91008.1 - 0.041 13.8 7.6 2.7 7.9 0.0 4.6 3 1 2 5 5 5 0 Thioredoxin ATG22 PF11700.3 GAO91009.1 - 6.8e-213 707.4 19.5 7.8e-213 707.2 13.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAO91009.1 - 6.6e-08 31.6 52.7 8.2e-08 31.3 12.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Med14 PF08638.6 GAO91010.1 - 3e-74 248.4 0.0 5e-74 247.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Herpes_UL36 PF03586.8 GAO91010.1 - 0.018 14.1 0.2 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DNA_pol_E_B PF04042.11 GAO91011.1 - 1.4e-49 168.1 0.0 2e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 GAO91012.1 - 5.5e-14 51.1 0.2 5.5e-14 51.1 0.2 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 GAO91012.1 - 0.00035 20.4 12.2 0.0097 15.8 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAO91012.1 - 0.00046 19.7 11.2 0.045 13.3 0.0 3.6 4 0 0 4 4 4 2 TPR repeat CCDC-167 PF15188.1 GAO91012.1 - 0.034 14.1 5.3 0.087 12.7 3.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_16 PF13432.1 GAO91012.1 - 1.9 9.2 14.5 3.4 8.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAO91012.1 - 3 7.5 8.0 15 5.3 0.7 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DWNN PF08783.6 GAO91013.1 - 1.4e-32 111.4 0.7 3.3e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 DWNN domain Yippee-Mis18 PF03226.9 GAO91013.1 - 1.2e-16 60.4 0.0 3.3e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CCHC_2 PF13696.1 GAO91013.1 - 1.2e-05 24.7 7.3 2.7e-05 23.5 5.1 1.6 1 0 0 1 1 1 1 Zinc knuckle ODC_AZ PF02100.12 GAO91013.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme zf-CCHC PF00098.18 GAO91013.1 - 0.027 14.3 1.2 0.027 14.3 0.8 1.8 2 0 0 2 2 2 0 Zinc knuckle His_biosynth PF00977.16 GAO91014.1 - 6.4e-47 159.7 0.3 2.1e-46 158.0 0.2 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 GAO91014.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 GAO91014.1 - 1.8e-08 34.2 0.0 1.4e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAO91014.1 - 1.5e-07 31.1 0.0 3.9e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 GAO91014.1 - 0.0026 17.2 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Dus PF01207.12 GAO91014.1 - 0.0083 14.9 0.0 0.022 13.5 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Peptidase_S51 PF03575.12 GAO91014.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ThiF PF00899.16 GAO91015.1 - 1.1e-27 96.5 0.0 1.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 GAO91015.1 - 0.0033 17.5 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAO91015.1 - 0.085 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAO91015.1 - 0.21 10.7 0.0 0.49 9.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.14 GAO91016.1 - 1.5e-60 204.2 0.0 1.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 GAO91016.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAO91016.1 - 0.015 15.8 0.0 0.045 14.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAO91016.1 - 0.061 12.9 0.0 0.24 10.9 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain FUSC PF04632.7 GAO91017.1 - 2.4 6.4 16.2 3.5 5.9 11.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.1 GAO91017.1 - 7.4 5.7 37.8 0.72 9.0 9.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 GAO91017.1 - 9.8 4.1 44.5 0.71 7.8 23.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein OST3_OST6 PF04756.8 GAO91018.1 - 1.7e-20 73.1 5.8 1.8e-20 73.1 3.3 1.5 2 0 0 2 2 2 1 OST3 / OST6 family Activator-TraM PF11657.3 GAO91018.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM VIT1 PF01988.14 GAO91018.1 - 1.7 8.0 10.6 0.73 9.2 0.9 2.2 1 1 1 2 2 2 0 VIT family DUF4149 PF13664.1 GAO91018.1 - 2.2 8.3 6.2 7.5 6.6 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Rft-1 PF04506.8 GAO91019.1 - 3.2e-87 293.1 21.1 4e-87 292.8 14.6 1.0 1 0 0 1 1 1 1 Rft protein DEAD PF00270.24 GAO91020.1 - 5.7e-48 162.5 0.0 2.1e-47 160.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO91020.1 - 1.6e-27 95.1 0.0 9.6e-26 89.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO91020.1 - 1.5e-05 24.9 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 GAO91020.1 - 0.0026 16.2 0.0 0.039 12.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 GAO91020.1 - 0.0069 15.4 0.6 0.031 13.3 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Rep_fac-A_C PF08646.5 GAO91021.1 - 1.8e-58 196.3 1.3 1.4e-55 187.0 0.2 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 GAO91021.1 - 1e-13 50.9 0.3 4.9e-10 39.1 0.0 3.6 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 GAO91021.1 - 2.3e-09 36.9 0.0 5.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 GAO91021.1 - 0.068 13.2 0.1 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF223 UCH PF00443.24 GAO91022.1 - 1.1e-47 162.3 0.0 2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAO91022.1 - 1.6e-23 82.5 12.3 1.3e-19 70.0 1.4 3.0 2 1 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 GAO91022.1 - 5.8e-22 76.9 0.1 6.2e-10 38.6 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 GAO91022.1 - 1.5e-19 70.5 0.0 1.8e-09 37.4 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 GAO91022.1 - 0.014 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF2180 PF09947.4 GAO91022.1 - 1.3 8.8 9.9 20 5.0 0.3 4.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Mitofilin PF09731.4 GAO91023.1 - 1.4 7.4 15.5 1.7 7.2 10.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RNase_H2-Ydr279 PF09468.5 GAO91023.1 - 2.2 7.3 6.0 3.2 6.8 4.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DNA_pol3_a_NII PF11490.3 GAO91023.1 - 6.4 6.4 13.3 0.48 10.0 4.6 1.9 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II CFEM PF05730.6 GAO91024.1 - 5.2e-05 22.9 5.6 5.2e-05 22.9 3.9 1.9 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.5 GAO91024.1 - 0.067 12.8 1.9 0.19 11.3 1.3 1.7 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like MTBP_C PF14920.1 GAO91024.1 - 6.7 6.1 6.9 7.5 5.9 4.8 1.2 1 0 0 1 1 1 0 MDM2-binding DEAD PF00270.24 GAO91025.1 - 5.9e-15 55.1 0.0 1.5e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAO91025.1 - 1.4e-10 40.8 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAO91025.1 - 0.00018 21.3 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ECH PF00378.15 GAO91025.1 - 0.1 11.7 0.1 4.3 6.3 0.1 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Helicase_C PF00271.26 GAO91027.1 - 7.9e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAO91027.1 - 0.00013 21.4 0.1 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 2 DEAD/DEAH box helicase Collagen PF01391.13 GAO91030.1 - 0.0012 18.2 8.5 0.0021 17.5 5.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glutenin_hmw PF03157.8 GAO91030.1 - 0.014 13.6 11.6 0.017 13.4 8.0 1.0 1 0 0 1 1 1 0 High molecular weight glutenin subunit LEA_3 PF03242.8 GAO91030.1 - 0.13 12.5 0.8 0.23 11.7 0.5 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein CIAPIN1 PF05093.8 GAO91031.1 - 1e-33 115.3 2.6 1.6e-33 114.7 1.8 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DDE_1 PF03184.14 GAO91032.1 - 2e-58 197.0 0.0 7e-58 195.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAO91032.1 - 2.9e-15 55.7 0.1 7.6e-15 54.4 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF1087 PF06465.8 GAO91032.1 - 1e-09 38.1 0.8 2.3e-09 37.0 0.5 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) HTH_psq PF05225.11 GAO91032.1 - 2.1e-08 33.5 0.0 5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain zf-CCHC_4 PF14392.1 GAO91032.1 - 0.031 13.9 1.0 0.083 12.5 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Acyl-ACP_TE PF01643.12 GAO91033.1 - 0.006 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF3395 PF11875.3 GAO91034.1 - 1e-47 161.5 3.0 1.3e-47 161.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DDE_1 PF03184.14 GAO91036.1 - 0.0089 15.1 0.3 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAO91036.1 - 0.019 14.7 0.1 0.085 12.6 0.0 2.0 1 1 1 2 2 2 0 Tc5 transposase DNA-binding domain